Basic Information
Gene ID GSOIDP00000593001
Gene Name NR1H3
Full Name Oxysterols receptor LXR-alpha
Organism Oikopleura dioica [34765]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
GSOIDP00000593001 Gene3D G3DSA:1.10.565.10 IPR000536 159 412 4.60e-29 Nuclear hormone receptor, ligand-binding domain
GSOIDP00000593001 Pfam PF00104 IPR000536 232 403 7.00e-09 Nuclear hormone receptor, ligand-binding domain
GSOIDP00000593001 PRINTS PR00398 IPR001723 384 401 4.90e-13 Nuclear hormone receptor
GSOIDP00000593001 PRINTS PR00398 IPR001723 259 275 4.90e-13 Nuclear hormone receptor
GSOIDP00000593001 PRINTS PR00398 IPR001723 326 341 4.90e-13 Nuclear hormone receptor
GSOIDP00000593001 PRINTS PR00398 IPR001723 238 259 4.90e-13 Nuclear hormone receptor
GSOIDP00000593001 PRINTS PR00546 IPR001728 326 348 3.20e-05 Thyroid hormone receptor
GSOIDP00000593001 PRINTS PR00546 IPR001728 235 256 3.20e-05 Thyroid hormone receptor
GSOIDP00000593001 PRINTS PR00546 IPR001728 261 280 3.20e-05 Thyroid hormone receptor
GSOIDP00000593001 SMART SM00430 IPR000536 237 396 3.10e-08 Nuclear hormone receptor, ligand-binding domain
GSOIDP00000593001 SUPERFAMILY SSF48508 IPR000536 214 408 4.20e-29 Nuclear hormone receptor, ligand-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
GSOIDP00000593001 PF00104 7.6e-10 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
GSOIDP00000593001 GO:0030522 biological_process intracellular receptor signaling pathway
GSOIDP00000593001 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
GSOIDP00000593001 GO:0050728 biological_process negative regulation of inflammatory response
GSOIDP00000593001 GO:0090341 biological_process negative regulation of secretion of lysosomal enzymes
GSOIDP00000593001 GO:0090188 biological_process negative regulation of pancreatic juice secretion
GSOIDP00000593001 GO:0010887 biological_process negative regulation of cholesterol storage
GSOIDP00000593001 GO:0010875 biological_process positive regulation of cholesterol efflux
GSOIDP00000593001 GO:0070328 biological_process triglyceride homeostasis
GSOIDP00000593001 GO:0071222 biological_process cellular response to lipopolysaccharide
GSOIDP00000593001 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
GSOIDP00000593001 GO:0043031 biological_process negative regulation of macrophage activation
GSOIDP00000593001 GO:0042632 biological_process cholesterol homeostasis
GSOIDP00000593001 GO:0043401 biological_process steroid hormone mediated signaling pathway
GSOIDP00000593001 GO:2000188 biological_process regulation of cholesterol homeostasis
GSOIDP00000593001 GO:0045893 biological_process positive regulation of transcription, DNA-templated
GSOIDP00000593001 GO:0005634 cellular_component nucleus
GSOIDP00000593001 GO:0090575 cellular_component RNA polymerase II transcription factor complex
GSOIDP00000593001 GO:0003707 molecular_function steroid hormone receptor activity
GSOIDP00000593001 GO:0004879 molecular_function RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GSOIDP00000593001 GO:0043565 molecular_function sequence-specific DNA binding
GSOIDP00000593001 GO:0008270 molecular_function zinc ion binding