Basic Information
Gene ID GSOIDP00017450001
Gene Name Nr1h3
Full Name Oxysterols receptor LXR-alpha
Organism Oikopleura dioica [34765]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
GSOIDP00017450001 Gene3D G3DSA:3.30.50.10 IPR013088 58 136 4.50e-17 Zinc finger, NHR/GATA-type
GSOIDP00017450001 Gene3D G3DSA:1.10.565.10 IPR000536 137 157 9.20e-11 Nuclear hormone receptor, ligand-binding domain
GSOIDP00017450001 Gene3D G3DSA:1.10.565.10 IPR000536 203 344 9.20e-11 Nuclear hormone receptor, ligand-binding domain
GSOIDP00017450001 Pfam PF00105 IPR001628 62 138 1.20e-10 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 PRINTS PR00047 IPR001628 79 94 1.00e-08 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 PRINTS PR00047 IPR001628 130 138 1.00e-08 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 PRINTS PR00047 IPR001628 122 130 1.00e-08 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 PRINTS PR00047 IPR001628 63 79 1.00e-08 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 ProSiteProfiles PS51030 IPR001628 60 145 1.44e+01 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 SMART SM00399 IPR001628 60 141 4.00e-11 Zinc finger, nuclear hormone receptor-type
GSOIDP00017450001 SUPERFAMILY SSF48508 IPR000536 228 345 2.87e-05 Nuclear hormone receptor, ligand-binding domain

Pfam Annotation
Protein Pfam ID E.value Name Description
GSOIDP00017450001 PF00105 1e-11 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
GSOIDP00017450001 GO:0090188 biological_process negative regulation of pancreatic juice secretion
GSOIDP00017450001 GO:0090341 biological_process negative regulation of secretion of lysosomal enzymes
GSOIDP00017450001 GO:0010887 biological_process negative regulation of cholesterol storage
GSOIDP00017450001 GO:0010875 biological_process positive regulation of cholesterol efflux
GSOIDP00017450001 GO:0030522 biological_process intracellular receptor signaling pathway
GSOIDP00017450001 GO:0000122 biological_process negative regulation of transcription from RNA polymerase II promoter
GSOIDP00017450001 GO:0050728 biological_process negative regulation of inflammatory response
GSOIDP00017450001 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
GSOIDP00017450001 GO:0043031 biological_process negative regulation of macrophage activation
GSOIDP00017450001 GO:2000188 biological_process regulation of cholesterol homeostasis
GSOIDP00017450001 GO:0043401 biological_process steroid hormone mediated signaling pathway
GSOIDP00017450001 GO:0042632 biological_process cholesterol homeostasis
GSOIDP00017450001 GO:0045893 biological_process positive regulation of transcription, DNA-templated
GSOIDP00017450001 GO:0071222 biological_process cellular response to lipopolysaccharide
GSOIDP00017450001 GO:0070328 biological_process triglyceride homeostasis
GSOIDP00017450001 GO:0090575 cellular_component RNA polymerase II transcription factor complex
GSOIDP00017450001 GO:0005634 cellular_component nucleus
GSOIDP00017450001 GO:0003707 molecular_function steroid hormone receptor activity
GSOIDP00017450001 GO:0004879 molecular_function RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
GSOIDP00017450001 GO:0008270 molecular_function zinc ion binding
GSOIDP00017450001 GO:0043565 molecular_function sequence-specific DNA binding