PredictBias

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 42.8 bits (101), Expect = 2e-06

		 Identities = 22/52 (42%), Positives = 29/52 (55%), Gaps = 8/52 (15%)

		

		Query: 352 TLNAAKALGIEDNVGSLVVGKQADFCLWDIATPAQLAYSYGVNPCKDVVKNG 403

		           T+N A A G+   +GSL VGK+AD  LW+   PA     +GV P   V+  G

		Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVLWN---PAF----FGVKP-DMVLLGG 453

		

		

		

		 Score = 32.8 bits (75), Expect = 0.002

		 Identities = 19/61 (31%), Positives = 29/61 (47%), Gaps = 6/61 (9%)

		

		Query: 23  YGAITNAAIAVKDGKIAWLGPRSE---LPAFDVL---SIPVYRGKGGWITPGLIDAHTHL 76

		           +  I  A I +KDG+IA +G        P   ++      V  G+G  +T G +D+H H 

		Sbjct: 80  HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHF 139

		

		Query: 77  I 77

		           I

		Sbjct: 140 I 140

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 44.2 bits (104), Expect = 4e-08

		 Identities = 20/94 (21%), Positives = 43/94 (45%), Gaps = 6/94 (6%)

		

		Query: 71  YILFYHQQAVGKVMLDISEYRIHLVDFIII-PSMRGRGFGSAILAAIKQEAMKRHLP-VG 128

		           ++ +     +G++ +  +     L++ I +    R +G G+A+L    + A + H   + 

		Sbjct: 68  FLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLM 127

		

		Query: 129 LSVESENTQAKKLYLQHGFKLESYSGAYESMLWR 162

		           L  +  N  A   Y +H F +    GA ++ML+ 

		Sbjct: 128 LETQDINISACHFYAKHHFII----GAVDTMLYS 157

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score = 48.4 bits (115), Expect = 4e-07

		 Identities = 39/180 (21%), Positives = 57/180 (31%), Gaps = 26/180 (14%)

		

		Query: 3505 AVLLAGTVSQANAA---DNWYVEGFVGQAQVDSSRRDLQPQTAAGVVTSVDDKDTAFGLS 3561

		            AV LAG  + A AA   + WY    +G +Q   +                 +     G  

		Sbjct: 9    AVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTG-------FINNNGPTHENQLGAGAF 61

		

		Query: 3562 VGYQWTPMVAIELGYADFGNGSARIEGASLTPAQYHEQVKAVTPVLADGVMLGLRFTLLQ 3621

		             GYQ  P V  E+GY   G    R+          ++         A GV L  +     

		Sbjct: 62   GGYQVNPYVGFEMGYDWLG----RMPYKGSVENGAYK---------AQGVQLTAKLGYPI 108

		

		Query: 3622 HDAWRFEVPIGLFRWQADISSTMGNNRLTTELDGTDWYAGVRFSYQVSDAWSVGLGYQYV 3681

		             D       +G   W+AD  S +      T   G          Y ++   +  L YQ+ 

		Sbjct: 109  TDDLDIYTRLGGMVWRADTKSNVYGKNHDT---GVSPVFAGGVEYAITPEIATRLEYQWT 165

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 36.8 bits (85), Expect = 1e-05

		 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 3/84 (3%)

		

		Query: 55  NNLAGCGALKWLDAEHAEIKSMRTAAPYKQQGIASKILQHLINDAKSAGVKRLSLETGSM 114

		           NN  G   ++     +A I+ +  A  Y+++G+ + +L   I  AK      L LET  +

		Sbjct: 74  NNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDI 133

		

		Query: 115 DFFNPARLLYCKFGFEICGPFDTY 138

		           +    A   Y K  F I    DT 

		Sbjct: 134 NI--SACHFYAKHHFIIGA-VDTM 154

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  104 bits (260), Expect = 3e-29

		 Identities = 67/248 (27%), Positives = 113/248 (45%), Gaps = 15/248 (6%)

		

		Query: 5   VLVTGSSRGIGKAIALKLAQAGFDIALHYHSNQTAADDTATQIRALGVNVSLLKFDVAER 64

		             +TG+++GIG+A+A  LA  G  IA     N    +   + ++A   +      DV + 

		Sbjct: 11  AFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69

		

		Query: 65  ATVKAAIEADIETNGAYYGVILNAGINRDTAFPAMTESEWDSVIHTNLDGFYNVIHPCVM 124

		           A +           G    ++  AG+ R     ++++ EW++    N  G +N     V 

		Sbjct: 70  AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS-VS 128

		

		Query: 125 PMVQGRKGGRIITLASVSGIAGNRGQVNYSASKAGIIGATKALSLELAKRKITVNCIAPG 184

		             +  R+ G I+T+ S            Y++SKA  +  TK L LELA+  I  N ++PG

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188

		

		Query: 185 LIETDM----------VADIPKDMVEQL---VPMRRMGKPNEIAALAAFLMSDDAAYITR 231

		             ETDM             + K  +E     +P++++ KP++IA    FL+S  A +IT 

		Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248

		

		Query: 232 QVISVNGG 239

		             + V+GG

		Sbjct: 249 HNLCVDGG 256

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 35.2 bits (81), Expect = 0.001

		 Identities = 20/122 (16%), Positives = 46/122 (37%), Gaps = 17/122 (13%)

		

		Query: 686 RLLTLKLLALALGIALLLFSLNFGFKKAAVVVAVPALAALLTLATLGLTGSPLSLFHALA 745

		           +   L  ++  + + L L +L   +     V+ V  L  +  L    L      ++  + 

		Sbjct: 871 QAPALVAISFVV-VFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVG 929

		

		Query: 746 LILVFGIG-------IDYSLFFASAQNHG--KAVMMA-------VFMSACSTLLAFGLLA 789

		           L+   G+        ++++      +  G  +A +MA       + M++ + +L    LA

		Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989

		

		Query: 790 FS 791

		            S

		Sbjct: 990 IS 991

		

		

		

		 Score = 34.8 bits (80), Expect = 0.001

		 Identities = 26/153 (16%), Positives = 50/153 (32%), Gaps = 23/153 (15%)

		

		Query: 692 LLALALGIALLLFSLNFGFKKAAVVVAVPALAALLTLATLGLTGSPLSLFHALALILVFG 751

		             A+ L   ++   L          +AVP +  L T A L   G  ++      ++L  G

		Sbjct: 345 FEAIMLVFLVMYLFLQNMRATLIPTIAVP-VVLLGTFAILAAFGYSINTLTMFGMVLAIG 403

		

		Query: 752 IGIDYSL----------------FFASAQNHGKAVMMAVFMSACSTLLAFGLLAFSQTQA 795

		           + +D ++                   + +     +  A+   A      F  +AF     

		Sbjct: 404 LLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGST 463

		

		Query: 796 ---IHYFGLTLSLGIGFTFLLSPLILTTTQALT 825

		                 F +T+   +  + L++   L  T AL 

		Sbjct: 464 GAIYRQFSITIVSAMALSVLVA---LILTPALC 493

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 40.6 bits (95), Expect = 2e-05

		 Identities = 30/84 (35%), Positives = 39/84 (46%), Gaps = 8/84 (9%)

		

		Query: 294 MRLVQGDV-----GSGKTLVAAMAA-LQAIENGYQVAMMAPTELLAEQHATNFAAWFEPL 347

		           M L +  +     G GKTL A + A L A+  G  V ++   + LA++ A N    FE L

		Sbjct: 92  MVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFEFL 150

		

		Query: 348 GLKVGW-LAGKLKGKARTQSLADI 370

		           GL VG  L G      R    ADI

		Sbjct: 151 GLTVGINLPGMPAPAKREAYAADI 174

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 76.4 bits (188), Expect = 1e-18

		 Identities = 29/117 (24%), Positives = 51/117 (43%), Gaps = 1/117 (0%)

		

		Query: 2   KILLAEDQAMVRGALAALLTLAGGFNITQASDGDEALSLLKQQSFDLLLTDIEMPGRTGL 61

		            IL+A+D A +R  L   L+ AG +++   S+       +     DL++TD+ MP     

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAG-YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63

		

		Query: 62  ELAAWLKDQHSQTKVVVITTFGRAGYIKRAIEAGVGGFLLKDAPSETLVNAIQQVMA 118

		           +L   +K       V+V++         +A E G   +L K      L+  I + +A

		Sbjct: 64  DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 34.8 bits (80), Expect = 4e-04

		 Identities = 67/376 (17%), Positives = 125/376 (33%), Gaps = 51/376 (13%)

		

		Query: 1   MTSTHLQLERKLAWVYLINLVFYLIPLAINAYPAWKIALSFAVLVPFIASYFWAYK-CNQ 59

		           M STH Q  +   +   I    Y +     A       L   +    I+          +

		Sbjct: 1   MASTHRQANKYYWYCQGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYR 60

		

		Query: 60  NSAYRPILMMVAIATAITPINPGSISLFTFAAFFIGF-FYPLRTCLLAIAALIGLLFALN 118

		           +   R   + + +   I  + P  +         IG  ++   T +  + A I       

		Sbjct: 61  SFIKRQGWLKLNMGQIILRVLPACV--------VIGMVWFVANTSIWRLLAFINTKPVAF 112

		

		Query: 119 EIYDFNSYYFPLYGSGLVLGVGMFG------VAERRRHQHKLKEQQSTQEISTLAAMVER 172

		            +    S  F +     +  +  FG        +    Q K+       ++  L A +  

		Sbjct: 113 TLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINP 172

		

		Query: 173 ERIARDLHDIMGHSLSSIALKAELAEKLLAKQEYQLATIQLNELGQIARESLSQIR-HTV 231

		             +   L++I     + I      A ++L              L ++ R SL       V

		Sbjct: 173 HFMFNALNNIR----ALILEDPTKAREMLTS------------LSELMRYSLRYSNARQV 216

		

		Query: 232 SDYKHKGLADSVTQLCKLLREKGVSVELTGNIPKLPARMESQLGLIVTELVNNILRHSGA 291

		           S      + DS  QL  +  E  +  E   N   +  ++     ++V  LV N ++H G 

		Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPP---MLVQTLVENGIKH-GI 272

		

		Query: 292 SQC------IIDFIQQPNRLVVEVKDNGP----SKPIAEGNGLTGIRERLDSLGG---SL 338

		           +Q       ++   +    + +EV++ G     +   + G GL  +RERL  L G    +

		Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQI 332

		

		Query: 339 SYNLEQG-YAFTVSLP 353

		             + +QG     V +P

		Sbjct: 333 KLSEKQGKVNAMVLIP 348

		

		

		>PF07328#T-DNA border endonuclease VirD1

		          Length = 144

		

		 Score = 31.9 bits (72), Expect = 0.003

		 Identities = 17/68 (25%), Positives = 32/68 (47%), Gaps = 4/68 (5%)

		

		Query: 506 PEQIEKVI----RDTKHTTLDSLLADIGLGNAMSIVIAQRLIGDNLENQESRDGHMMPIR 561

		           P +++KVI     + +    D+ +A++GL    ++ IA R IG  +EN       +  + 

		Sbjct: 16  PARVDKVISVKMTEAELAEFDAQIAELGLNRNRALRIAARRIGGFVENDAKTVELLRDMS 75

		

		Query: 562 GAEGMLVT 569

		            A   + T

		Sbjct: 76  RAIAGVAT 83

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score = 68.2 bits (167), Expect = 8e-15

		 Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 20/221 (9%)

		

		Query: 150 SGMRMEAKVHIVTC----ANDMAKNITK-SVERCGLKVDDLVFSGIASADAVLTFDEKDL 204

		           S   M     ++ C    A  + +   + S +  G +   L+   +A+A        +  

		Sbjct: 100 SNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEAT 159

		

		Query: 205 GVCIVDIGGGTTDIAVYTNGALRHCAVVPVAGNQVTNDIAKIFR------TPSSHAEQIK 258

		           G  +VDIGGGTT++AV +   + + + V + G++    I    R         + AE+IK

		Sbjct: 160 GSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIK 219

		

		Query: 259 VQFACARSSMVSREDSIEVPS---VGGRPSR-SMSRHTLAEVVEPRYQELFELVLKELKD 314

		            +   A          IEV       G P   +++ + + E ++     +   V+  L+ 

		Sbjct: 220 HEIGSAYPG--DEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQ 277

		

		Query: 315 SGLE---DQIAAGIVLTGGTASIQGVVDIAEATFGMPVRVA 352

		              E   D    G+VLTGG A ++ +  +     G+PV VA

		Sbjct: 278 CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318

		

		

		>TONBPROTEIN#Gram-negative bacterial tonB protein signature.

		          Length = 239

		

		 Score = 29.2 bits (65), Expect = 0.022

		 Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 5/96 (5%)

		

		Query: 292 TVVVGAVIDPEMSDELRVTVVATGIGAEKRPDIQLVSKPAPRPEPVVVEPKVEAYVEEAV 351

		           T V   +  P  +  + VT+V      E    +Q   +P   PEP   EP+      +  

		Sbjct: 30  TSVHQVIELPAPAQPISVTMVTP-ADLEPPQAVQPPPEPVVEPEP---EPEPIPEPPKEA 85

		

		Query: 352 HVNYAAPKGNVLPAAPQPAPQPAPSTKHELDYLDIP 387

		            V    PK    P  P+P  +     K ++  ++  

		Sbjct: 86  PVVIEKPKPKPKP-KPKPVKKVQEQPKRDVKPVESR 120

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 70.2 bits (172), Expect = 7e-16

		 Identities = 44/182 (24%), Positives = 68/182 (37%), Gaps = 24/182 (13%)

		

		Query: 3   KIMVTGATGLLGRAVVKQLELTGHEVV-----------------ATGFSRASERVHKLDL 45

		           K +VTGA G +G  V K+L   GH+VV                     ++   + HK+DL

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61

		

		Query: 46  TAPLAVEAFIAREQPQVIVHCAAERRPDVSEQNPQAALALNLTAS-QALAMAVKANNAWL 104

		                +    A    + +           S +NP A    NLT     L          L

		Sbjct: 62  ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121

		

		Query: 105 IYISTDYVFDGTQ--PKYAEDAATHPVNFYGESKLKGEEIVLNTSADFAV----LRLPIL 158

		           +Y S+  V+   +  P   +D+  HPV+ Y  +K   E +    S  + +    LR   +

		Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181

		

		Query: 159 YG 160

		           YG

		Sbjct: 182 YG 183

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 92.2 bits (229), Expect = 2e-24

		 Identities = 26/129 (20%), Positives = 64/129 (49%)

		

		Query: 3   RLLIVEDDLSLASILGRRLTRHGFECRLTHDASDALLVAREFRPSHILLDMKLAEANGLG 62

		            +L+ +DD ++ ++L + L+R G++ R+T +A+             ++ D+ + + N   

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 63  LIVPLRNLLPKVTMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLAALEMEGHSHTL 122

		           L+  ++   P + +++++   +  TA++A   GA +YL KP D   L+  +         

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124

		

		Query: 123 QEDEVDDSP 131

		           +  +++D  

		Sbjct: 125 RPSKLEDDS 133

		

		

		

		 Score = 47.1 bits (112), Expect = 1e-08

		 Identities = 13/39 (33%), Positives = 22/39 (56%)

		

		Query: 135 KRLEWEHIQQVLNANQGNVSATARQLGMHRRTLQRKLLK 173

		             +E+  I   L A +GN    A  LG++R TL++K+ +

		Sbjct: 434 AEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472

		

		

		>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature.

		          Length = 544

		

		 Score =  360 bits (926), Expect = e-118

		 Identities = 133/490 (27%), Positives = 191/490 (38%), Gaps = 51/490 (10%)

		

		Query: 44  SQFNL--DAGSQLKVEKKLDLGQGKQKQRLQQYFHDVPVYGFSVATSQSSMGFYSDMSGR 101

		           + F L   A  +L +        G    R +Q        G  +    +     S +SG 

		Sbjct: 64  NTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVNDGELSS-LSGT 122

		

		Query: 102 VLKNIEKSADFVKPTLTANKALDIAIRGKSEK-AVAGLKAENKQAKLWLYLDDAAKTRLV 160

		           ++ N++K     +  ++  +A  IA +  +++       AE  +    +   D    RL 

		Sbjct: 123 LIPNLDKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLA 182

		

		Query: 161 YVTSFVVYGDEPSRPFTMIDAHSGEVLKRWEGINHA-ASGTGPGGNIKTGQYEYGTDFSY 219

		           Y  +       P     MIDA  G+VL +W  ++ A   G  P     T     G     

		Sbjct: 183 YEVNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRG----- 237

		

		Query: 220 LDVEVSGDT---CTMNSPNVKTVNLNGATSGATAFSYTCPRNTV-----------KEING 265

		               V GD     T  S       L   T G+  F+Y     TV           +    

		Sbjct: 238 ----VLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFAS 293

		

		Query: 266 AYSPLNDAHYFGNVIYNMYSEWYN---TAPLTFQLTMRVHYSSNYENAFWDGSAMTFGDG 322

		             +   DAHY+  V+Y+ Y   +           +   VHY   Y NAFW+GS M +GDG

		Sbjct: 294 YDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQMVYGDG 353

		

		Query: 323 -ATTFYPLV-SLDVSAHEVSHGFTEQNSGLIYDAQSGGMNEAFSDMAGEAAEFYMHGTND 380

		              TF P    +DV  HE++H  T+  +GL+Y  +SG +NEA SD+ G   EFY +   D

		Sbjct: 354 DGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPD 413

		

		Query: 381 WLVGADIFK---GNGALRYMADPTLDGISIGHIDDYYDGID---VHHSSGVFNKAFYTLA 434

		           W +G DI+       ALR M+DP   G    +   Y    D   VH +SG+ NKA Y L+

		Sbjct: 414 WEIGEDIYTPGVAGDALRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLS 473

		

		Query: 435 N--------LPGWDTRTAFQTFVVANQLYWTADSLFWQGACGVKSAATDLG----LSADD 482

		                    + G       + F  A   Y T  S F Q       AA DL        + 

		Sbjct: 474 QGGVHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNS 533

		

		Query: 483 VVTAFAAVGI 492

		           V  AF AVG+

		Sbjct: 534 VKQAFNAVGV 543

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 58.9 bits (142), Expect = 2e-12

		 Identities = 47/241 (19%), Positives = 88/241 (36%), Gaps = 47/241 (19%)

		

		Query: 3   VLIVGGSGGIGQAMVKQVQETYPDATVHATYRHHLPQDRQNNIQWHA----------LDV 52

		             I G + GIG+A    V  T      H     + P+  +  +               DV

		Sbjct: 11  AFITGAAQGIGEA----VARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66

		

		Query: 53  TNEAEIKQLSEQLTE----LDWLINCVGILHTQDKGPEKSLQSLDIAFFQHNLTLNTLPS 108

		            + A I +++ ++      +D L+N  G+L     G   SL   +   ++   ++N+   

		Sbjct: 67  RDSAAIDEITARIEREMGPIDILVNVAGVLRP---GLIHSLSDEE---WEATFSVNSTGV 120

		

		Query: 109 VMLAKHFCHALKQSDSARFAVISAKVGSITDNRLGGWYSYRASKAALNMFLKTLSIEWQR 168

		              ++     +    S     + +    +    +    +Y +SKAA  MF K L +E   

		Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMA---AYASSKAAAVMFTKCLGLELAE 177

		

		Query: 169 TMKHCVVLSLHPGTTDTPLSQP------------------FQQSVPKGKLFTPEYVANCL 210

		               C ++S  PG+T+T +                     F+  +P  KL  P  +A+ +

		Sbjct: 178 YNIRCNIVS--PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235

		

		Query: 211 L 211

		           L

		Sbjct: 236 L 236

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score = 70.3 bits (172), Expect = 1e-16

		 Identities = 51/206 (24%), Positives = 76/206 (36%), Gaps = 29/206 (14%)

		

		Query: 1   MKNTILTLAAIISLASVSVYSHAENMKNNDVAENGIYVGANYGY------LKVDGKDDFD 54

		           MK T + +A +      +V   A         +N  Y GA  G+        ++      

		Sbjct: 1   MKKTAIAIA-VALAGFATVAQAAPK-------DNTWYTGAKLGWSQYHDTGFINNNGPTH 52

		

		Query: 55  DNSDVIQGLVGYRFNQYLAIEGGYVNFGDY---GNSLSNA-ETDGYTAALKVSYPIVDRV 110

		           +N        GY+ N Y+  E GY   G     G+  + A +  G     K+ YPI D +

		Sbjct: 53  ENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDL 112

		

		Query: 111 ELYAKGGQLWYSTDYDVLGFSGNKDDEGV--FAGAGVAFKVTDRFLINAEYTWYDAGITV 168

		           ++Y + G + +  D       G   D GV      GV + +T       EY W       

		Sbjct: 113 DIYTRLGGMVWRADTKSNV-YGKNHDTGVSPVFAGGVEYAITPEIATRLEYQW------T 165

		

		Query: 169 ENVSNGA--DTDTDFKQASLGVEYRF 192

		            N+ +     T  D    SLGV YRF

		Sbjct: 166 NNIGDAHTIGTRPDNGMLSLGVSYRF 191

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 86.1 bits (213), Expect = 3e-20

		 Identities = 73/358 (20%), Positives = 139/358 (38%), Gaps = 48/358 (13%)

		

		Query: 48  LWVGIAIGAYGLTQAVLQIPMGILSDKYGRKPIILIGLVLFAIGSLIAANADSIYGV-VF 106

		            WV     A+ LT ++     G LSD+ G K ++L G+++   GS+I     S + + + 

		Sbjct: 52  NWV---NTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIM 108

		

		Query: 107 GRAVQGMGAIA--AAVLALAADLTRDEQRTKVMAIIGMCIGGSFALSLLVGPIVAQHVGL 164

		            R +QG GA A  A V+ + A     E R K   +IG  +     +   +G ++A ++  

		Sbjct: 109 ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW 168

		

		Query: 165 SGLFFLTAILAVTGMLIVQFLVPNPISHAP---KGDTLATPARLKRML-------TDPQL 214

		           S L  +  I  +T   +++ L            KG  L +   +  ML       +   +

		Sbjct: 169 SYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIV 228

		

		Query: 215 FRLDAGIFILHL-----------------VLTAVFVALPLDLVDAGLVKEKHWMLYF--- 254

		             L   IF+ H+                  +  V     +    AG V    +M+     

		Sbjct: 229 SVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288

		

		Query: 255 --PAFVGAFFL---MVPLIIIG------VKRKNTKAMFQIALVIMIVALLAMALFSN-NL 302

		              A +G+  +    + +II G      V R+    +  I +  + V+ L  +       

		Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTS 348

		

		Query: 303 WVLSFAVVLFFTGFNYLEASLPSLIAKFCPVGEKGSAMGVYSTSQFLGAFCGGMLGGG 360

		           W ++  +V    G ++ +  + ++++      E G+ M + + + FL    G  + GG

		Sbjct: 349 WFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406

		

		

		

		 Score = 31.0 bits (70), Expect = 0.010

		 Identities = 18/111 (16%), Positives = 43/111 (38%)

		

		Query: 274 RKNTKAMFQIALVIMIVALLAMALFSNNLWVLSFAVVLFFTGFNYLEASLPSLIAKFCPV 333

		           +   K +    ++I     +   +  +   +L  A  +   G     A +  ++A++ P 

		Sbjct: 75  QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134

		

		Query: 334 GEKGSAMGVYSTSQFLGAFCGGMLGGGAFQLVGAVGVFIVAVILMSIWLFL 384

		             +G A G+  +   +G   G  +GG     +    + ++ +I +    FL

		Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFL 185

		

		

		>PF03544#Gram-negative bacterial tonB protein

		          Length = 243

		

		 Score = 29.2 bits (65), Expect = 0.013

		 Identities = 18/98 (18%), Positives = 33/98 (33%), Gaps = 4/98 (4%)

		

		Query: 125 PMGGGMPQNAGYQSAPQQAAPAQNQYAPAPQAAPAYQAPAQQQYAAPAPAQQQYGQQQAQ 184

		           P+   M   A  +       P +    P P+  P  + P +       P      + + +

		Sbjct: 49  PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKP----KPKPK 104

		

		Query: 185 PQQGGYAPKPQAAPAPAYQAPAAPAQRPAPQPQQNFTP 222

		           P+      +P+    P    PA+P +  AP    + T 

		Sbjct: 105 PKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTA 142

		

		

		>TYPE3OMGPROT#Type III secretion system outer membrane G protein

		           family signature.

		          Length = 607

		

		 Score = 31.8 bits (72), Expect = 0.002

		 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 4/76 (5%)

		

		Query: 37  QGEISHTKRKIKILSKINITLSLLKSNEQYG--IKRLFIKIKNTVIDEVKHHILQLNNLL 94

		           + E+S    K+ +L  I    +L +   +      RLFI I+  +IDE   H L L N  

		Sbjct: 465 RDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFI-IEPRIIDEGIAHHLALGNGQ 523

		

		Query: 95  K-KKGIQLIVEVEDQA 109

		             + GI  + E+ +Q+

		Sbjct: 524 DLRTGILTVDEISNQS 539

		

		

		>ANTHRAXTOXNA#Anthrax toxin LF subunit signature.

		          Length = 800

		

		 Score = 25.5 bits (55), Expect = 0.035

		 Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 5/67 (7%)

		

		Query: 27  VGYFPKSTTGDLYLKKVA----ALYLNDYWDILNSLSDCDIKYALNKYKNFQRYNKLIES 82

		           VG +  S   D + KK +    A YL+DY++  N +   + K  ++ ++  Q YN+ IE+

		Sbjct: 676 VGVYKDSGDKDEFAKKESVKKIAGYLSDYYNSANHIFSQEKKRKISIFRGIQAYNE-IEN 734

		

		Query: 83  TLASSLI 89

		            L S  I

		Sbjct: 735 VLKSKQI 741

		

		

		>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature.

		          Length = 591

		

		 Score =  327 bits (839), Expect = e-100

		 Identities = 173/409 (42%), Positives = 235/409 (57%), Gaps = 46/409 (11%)

		

		Query: 16  IVPLSLPKGGGAVTSMGMAPGNVGADGTASFSIPLPISAGRSGSTLTPPVAISYNSGAGN 75

		           I P  LPKGG A++         G DG AS ++PLPISA R      P +A+ Y+SG GN

		Sbjct: 15  ITPPFLPKGGKALSQ-------SGPDGLASITLPLPISAERG---FAPALALHYSSGGGN 64

		

		Query: 76  GIFGLGWQLPVMRISRRTRYGVPSFDESSDDQTDQYLGPDGEVLLPLLNEEGLVIIETRT 135

		           G FG+GW    M I+R T +GVP +++S     D++LGPDGEVL+  L+        T  

		Sbjct: 65  GPFGVGWSCATMSIARSTSHGVPQYNDS-----DEFLGPDGEVLVQTLSTGDAPNPVTCF 119

		

		Query: 136 TFRELEFEQAYQVCRYQPRVEGSFSRIERWWRDGEPASTFWLIHDATGHLHCLGKTIAGR 195

		            + ++ F Q+Y V RYQPR E SF R+E +W        FWL+HD+ G LH LGKT A R

		Sbjct: 120 AYGDVSFPQSYTVTRYQPRTESSFYRLE-YWVGNSNGDDFWLLHDSNGILHLLGKTAAAR 178

		

		Query: 196 VASPQLLTDSYNPRIGEWLLEESVSPTGEHMIYCYQDENNVGVSPDKQYS---LGTLPHL 252

		           ++ PQ    S+     +WL+EESV+P GEH+ Y Y  EN   V  +   +      + +L

		Sbjct: 179 LSDPQ--AASH---TAQWLVEESVTPAGEHIYYSYLAENGDNVDLNGNEAGRDRSAMRYL 233

		

		Query: 253 MEIRYGNLHPAANLYLWSSDNVNSATSGVEWLFKLIFDYGARGLDPHSQPQDKIEPDQHW 312

		            +++YGN  PAA+LYLW+S     AT  V+WLF L+FDYG RG+DP   P         W

		Sbjct: 234 SKVQYGNATPAADLYLWTS-----ATPAVQWLFTLVFDYGERGVDPQVPP--AFTAQNSW 286

		

		Query: 313 TARHDPFSRFDYGYEVRCHRLCRQIIMFHQNFTELNQGCPTVVGRLILDYDENAVLSRLI 372

		            AR DPFS ++YG+E+R HRLCRQ++MFH    EL +   T+V RL+L+YDEN +L++L 

		Sbjct: 287 LARQDPFSLYNYGFEIRLHRLCRQVLMFHHFPDELGEA-DTLVSRLLLEYDENPILTQLC 345

		

		Query: 373 GARLWAYDTDG---------KPQSQPPLFLNYTSFDTSSRPDA-WHVFQ 411

		            AR  AY+ DG          P   PP  +       SSRP + W + +

		Sbjct: 346 AARTLAYEGDGYRRAPVNNMMPPPPPPPMMG----GNSSRPKSKWAIVE 390

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 42.0 bits (98), Expect = 1e-05

		 Identities = 24/120 (20%), Positives = 42/120 (35%)

		

		Query: 745 NALANNTETNQVSVTVRDARNALVSGEEVSFSASNGATVETPTVLTNSNGVAIASIKSTQ 804

		           +A A+ TE    + TV+    A  +        S  A +   +  TN +G A  ++KS +

		Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628

		

		Query: 805 SGISTITASFNGTTKTVYVTFILVNCQSLGQSLEGACIDIFDADNNGKLFTSSPSVAYLD 864

		            G   ++A     T  +    ++   Q+     E          N     T +  V   D

		Sbjct: 629 PGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGD 688

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 41.2 bits (96), Expect = 2e-05

		 Identities = 35/164 (21%), Positives = 55/164 (33%), Gaps = 10/164 (6%)

		

		Query: 738 VERVNLNVSVDNVTSNGAEKNTVEATLYHSNNQPATGVDVSFKVNNGALFSNGTDSIIVR 797

		           V   +      +  ++G E  T  AT+   N      V VSF + +G    +   +    

		Sbjct: 558 VGVTDFTADKTSAKADGTEAITYTATV-KKNGVAQANVPVSFNIVSGTAVLSANSA---N 613

		

		Query: 798 TGRDGKASVEVASTTEGVVTVTAIYRDSTN-LNPDYTGITKVVNINFSTYLPDNIVYEG- 855

		           T   GKA+V + S   G V V+A   + T+ LN +          + +    D       

		Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVAN 673

		

		Query: 856 ----ISLTPLVSYNQAVAAGLEIDSTLELGYTIAVVNHIDATKY 895

		               I+ T  V       +  E+  T  LG         D   Y

		Sbjct: 674 GQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGY 717

		

		

		

		 Score = 37.7 bits (87), Expect = 3e-04

		 Identities = 21/101 (20%), Positives = 39/101 (38%), Gaps = 9/101 (8%)

		

		Query: 721 VSTTNTPLLVFCIAPLDVERVNLNVSVDNVTSNGAEKNTVEATLYHSNN-QPATGVDVSF 779

		            S  N   ++F       +     +  D  T+    ++ +  T+      +P +  +V+F

		Sbjct: 642 TSALNANAVIF---VDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTF 698

		

		Query: 780 KVNNGALFSNGTDSIIVRTGRDGKASVEVASTTEGVVTVTA 820

		               G L      +   +T  +G A V + STT G   V+A

		Sbjct: 699 TTTLGKL-----SNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 36.0 bits (83), Expect = 7e-04

		 Identities = 31/224 (13%), Positives = 68/224 (30%), Gaps = 23/224 (10%)

		

		Query: 411 QIGARYIYEDLFSADYFLG-YFSTGDIYQSANIKFGRLSLSAKAFDLDYNTRNFTLSNQL 469

		              +R    ++ + D  +       D Y  A  K G+L L+        +T   + S+Q 

		Sbjct: 492 TTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQT 551

		

		Query: 470 YGTNPY--KNFSISYSKPFFGGNGYLNYNNYSSKNYYGINNDNSIVIEKPIDYIYNINAL 527

		           Y       + F    +  F   N  L+Y+   +KN +    D  + +   I         

		Sbjct: 552 YWGTSNVDEQFQAGLNTAFEDINWTLSYS--LTKNAWQKGRDQMLALNVNI--------- 600

		

		Query: 528 NNVLNNALNNGSYSTISNENYNIGWSTNIYSGTLTLNSNYNSNSAYDEVKFGIYWSQRFG 587

		                   ++   S   ++  +   S ++        +N             + +S + G

		Sbjct: 601 ------PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTG 654

		

		Query: 588 KSVAGGLSVMTNNKGSSQYNNS---LSLNASNDNWYANHTVMAS 628

		            +  G  +  +    +  Y       ++  S+ +         S

		Sbjct: 655 YAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVS 698

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 43.1 bits (101), Expect = 6e-06

		 Identities = 17/81 (20%), Positives = 32/81 (39%)

		

		Query: 743 NALANNTVTNQVSVTVRDANNAPVAGQEVIFNASNNATVVTQTVLTDGNGVAIASIRSPQ 802

		           +A A+ T     + TV+    A           S  A +   +  T+G+G A  +++S +

		Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628

		

		Query: 803 SGISTVTASFNGTTKTVDVTF 823

		            G   V+A     T  ++   

		Sbjct: 629 PGQVVVSAKTAEMTSALNANA 649

		

		

		

		 Score = 42.4 bits (99), Expect = 1e-05

		 Identities = 40/148 (27%), Positives = 59/148 (39%), Gaps = 10/148 (6%)

		

		Query: 730 VDNDKSTIAVIFNNALANNTVTNQVSVTVRDANN-APVAGQEVIFNASNNATVVTQTVLT 788

		                + I      A+AN      ++ TV+      PV+ QEV F  +      + T  T

		Sbjct: 656 TKASITEIKADKTTAVANGQDA--ITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS-TEKT 712

		

		Query: 789 DGNGVAIASIRSPQSGISTVTASFNGTT---KTVDVTFNCQ-SLAGACIDIFDTG-SGKL 843

		           D NG A  ++ S   G S V+A  +      K  +V F    ++    I+I  TG  GKL

		Sbjct: 713 DTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKL 772

		

		Query: 844 FTNSPSVAYLNSIGGSAADGTYTETGTN 871

		            T       +N +  S  +G YT    N

		Sbjct: 773 PTVWLQYGQVN-LKASGGNGKYTWRSAN 799

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score = 59.6 bits (144), Expect = 5e-13

		 Identities = 40/203 (19%), Positives = 67/203 (33%), Gaps = 25/203 (12%)

		

		Query: 1   MRKFNLAVVIPLSIMSCSAVASYSDSSLELGVSAGQFNLKDS-----TGSYSGPSVGFNF 55

		           M+K  +A+ + L+  +  A A+  D++   G   G     D+      G      +G   

		Sbjct: 1   MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA 60

		

		Query: 56  I--RNFNDWFSFEGNYL------SSFNMDNANYDIQASTFSLAPVFTYHINDTFSIYGKG 107

		                 N +  FE  Y          +++N  Y  Q    +      Y I D   IY + 

		Sbjct: 61  FGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKL--GYPITDDLDIYTRL 118

		

		Query: 108 GASSMRITSSERNGLDFSYNTIGWFYGFGLNTSINNRINVRLGYETVTGDTGIEILGVTA 167

		           G    R  +            +   +  G+  +I   I  RL Y+          +G   

		Sbjct: 119 GGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTRP 178

		

		Query: 168 DGFSIQSSHTKISVISLGATYRF 190

		           D            ++SLG +YRF

		Sbjct: 179 D----------NGMLSLGVSYRF 191

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 90.3 bits (224), Expect = 3e-23

		 Identities = 32/171 (18%), Positives = 79/171 (46%), Gaps = 8/171 (4%)

		

		Query: 3   VLLVEDEQKIADFICEGLRAKHFNVTHCADGNQGYQAASNNTHDVIILDIMLPGRDGLDI 62

		           +L+ +D+  I   + + L    ++V   ++    ++  +    D+++ D+++P  +  D+

		Sbjct: 6   ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65

		

		Query: 63  LRSLRQQGVDTPIILLTARNELGDRVQGLDMGADDYLAKPFYVEELHARIQALLRRHGGT 122

		           L  +++   D P+++++A+N     ++  + GA DYL KPF + EL   I   L      

		Sbjct: 66  LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125

		

		Query: 123 QQHVVEVGALQLDCINRSINCQGQSVELTSREFSLLEHLMRSPNQVLTRGQ 173

		              + +     +  +       G+S  +    + +L  LM++   ++  G+

		Sbjct: 126 PSKLEDDSQDGMPLV-------GRSAAMQ-EIYRVLARLMQTDLTLMITGE 168

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 50.6 bits (121), Expect = 7e-09

		 Identities = 38/192 (19%), Positives = 70/192 (36%), Gaps = 29/192 (15%)

		

		Query: 118 AEQDNTKAKADLDKAKSTLALAKTKLERIEDLL---IKEPFALAKQDVDELRENVNLADA 174

		           A  +    K+ L++ +S +  AK + + +  L    I +       ++  L     LA  

		Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE--LAKN 321

		

		Query: 175 DFRQKQATMNDYLIKAPFDG---QLTSFSQSIGSQIGAGTALVTLYSLN-PVEVRYAISQ 230

		           + RQ+ +      I+AP      QL   ++  G  +     L+ +   +  +EV   +  

		Sbjct: 322 EERQQASV-----IRAPVSVKVQQLKVHTE--GGVVTTAETLMVIVPEDDTLEVTALVQN 374

		

		Query: 231 NDFGKAQKGQKVNVTVEAYGNKVFKGL---VNYVAP--AVDESSG-------RVEVHAAL 278

		            D G    GQ   + VEA+    +  L   V  +      D+  G        +E +   

		Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLS 434

		

		Query: 279 -DNPEFKLAPGM 289

		             N    L+ GM

		Sbjct: 435 TGNKNIPLSSGM 446

		

		

		

		 Score = 46.7 bits (111), Expect = 1e-07

		 Identities = 23/108 (21%), Positives = 44/108 (40%), Gaps = 7/108 (6%)

		

		Query: 100 ISAIHFSNGDKVTKGQVIAEQDNTKAKADLDKAKSTLALAKTKLERIEDLLIKEPFALAK 159

		           +  I    G+ V KG V+ +     A+AD  K +S+L  A+ +  R + L      ++  

		Sbjct: 107 VKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS----RSIEL 162

		

		Query: 160 QDVDELRENVNLADADFRQKQATMNDYLIKAPFDGQLTSFSQSIGSQI 207

		             + EL+        +  +++      LIK  F    T  +Q    ++

		Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS---TWQNQKYQKEL 207

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score =  651 bits (1680), Expect = 0.0

		 Identities = 301/1032 (29%), Positives = 509/1032 (49%), Gaps = 44/1032 (4%)

		

		Query: 8    IRHPIFASVLSIMAVLLGLIAFQKLDIQYFPEHTTHSASVNASIAGASADFMSSNVADKL 67

		            IR PIFA VL+I+ ++ G +A  +L +  +P     + SV+A+  GA A  +   V   +

		Sbjct: 6    IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65

		

		Query: 68   IAAASGIDKVDTM-STDCSEGRCSLTIKFNDDTS-DIEYTNLMNKLRSSVEGINDFPQSM 125

		                +GID +  M ST  S G  ++T+ F   T  DI    + NKL+ +       PQ  

		Sbjct: 66   EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLAT---PLLPQE- 121

		

		Query: 126  IDKPTVTDDTSATDSASNIITFVNAGGMEKQAMYDYISQQLVPQLKQVQGVGAVWGPYGG 185

		            + +  ++ + S++          +  G  +  + DY++  +   L ++ GVG V     G

		Sbjct: 122  VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV--QLFG 179

		

		Query: 186  SQKAVRVWLNPEQMKALNIKAADVVGTLGSYNASFTSG------AIKGKSRDFSINPLNQ 239

		            +Q A+R+WL+ + +    +   DV+  L   N    +G      A+ G+  + SI    +

		Sbjct: 180  AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239

		

		Query: 240  VETLEDVKDLVIKVS-EGKIIRVADVADVVMGEESLSPSILSIGGHSAMSLQILPLSNAN 298

		             +  E+   + ++V+ +G ++R+ DVA V +G E+ +  I  I G  A  L I   + AN

		Sbjct: 240  FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN-VIARINGKPAAGLGIKLATGAN 298

		

		Query: 299  PVTVASNIKAEIARMQQHLPQGLEMTLAYNQADFIEASIDEGFSALIEAVILVSLIVVLF 358

		             +  A  IKA++A +Q   PQG+++   Y+   F++ SI E    L EA++LV L++ LF

		Sbjct: 299  ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358

		

		Query: 359  LGSLRAASIPIITIPVCVIGVFAVMSALGFSINVLTILAIILAIGLVVDDAIVVVENCYR 418

		            L ++RA  IP I +PV ++G FA+++A G+SIN LT+  ++LAIGL+VDDAIVVVEN  R

		Sbjct: 359  LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418

		

		Query: 419  HI-ENGETPFNAAIKGCQEIIFPIIAMTLTLAAVYLPIGLMSGLTADLFRQFSFTLAAAV 477

		             + E+   P  A  K   +I   ++ + + L+AV++P+    G T  ++RQFS T+ +A+

		Sbjct: 419  VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478

		

		Query: 478  MISGVVALTLSPMMSAYLINTTEQQPK-----WFSRVEHVLQQLNDLYIKELDKWFTRKR 532

		             +S +VAL L+P + A L+     +       +F           + Y   + K      

		Sbjct: 479  ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538

		

		Query: 533  LMLGAAVVLIGLAGIAYWQLPKILLPAEDSGFIDVASNGPTGVGRQYHLNHNAELNGVMD 592

		              L    +++    + + +LP   LP ED G        P G  ++       ++     

		Sbjct: 539  RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598

		

		Query: 593  EHPAVGANLSY------IEGEPVN----HVLLKPWGERS---EGIDDVISDLMTKSKESV 639

		            ++        +        G+  N     V LKPW ER+      + VI     +  +  

		Sbjct: 599  KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658

		

		Query: 640  SAYNMSFSIRSANNLSIANNLRLELTTLDRNK---DELNDTAAKVQKLLEDYPG-LNNVG 695

		              + + F++ +   L  A     EL  +D+     D L     ++  +   +P  L +V 

		Sbjct: 659  DGFVIPFNMPAIVELGTATGFDFEL--IDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716

		

		Query: 696  NSVLRDQLRYDLSIDRNAIILSGVSYGDVTNALSTFLGSVKAADLHATDGFTYPIQVQVN 755

		             + L D  ++ L +D+      GVS  D+   +ST LG     D     G    + VQ +

		Sbjct: 717  PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF-IDRGRVKKLYVQAD 775

		

		Query: 756  LDKLSDFKVLNKLYVTSESGQALPLSQFVSIKQTTAESNIKTFMGLDSAELTADVMPGYS 815

		                   + ++KLYV S +G+ +P S F +         ++ + GL S E+  +  PG S

		Sbjct: 776  AKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTS 835

		

		Query: 816  TDEIKAYLDEQLPTLLNDAQGFKYNGVVKDLMDSQAGTQSLFLLALVFIYLILAAQFESF 875

		            + +  A + E L + L    G+ + G+      S     +L  ++ V ++L LAA +ES+

		Sbjct: 836  SGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESW 894

		

		Query: 876  VDPLIILLTVPLCIVGALLTLTLFGQSVNIYSQIGLLTLVGLVTKHGILLVEFANK-QQD 934

		              P+ ++L VPL IVG LL  TLF Q  ++Y  +GLLT +GL  K+ IL+VEFA    + 

		Sbjct: 895  SIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEK 954

		

		Query: 935  QGLSAIEAARSSAKSRLRPILMTSLTMILSAIPLALASGPGSLGLANIGLVLVGGLLAGT 994

		            +G   +EA   + + RLRPILMTSL  IL  +PLA+++G GS     +G+ ++GG+++ T

		Sbjct: 955  EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSAT 1014

		

		Query: 995  FFSLFVVPVAYV 1006

		              ++F VPV +V

		Sbjct: 1015 LLAIFFVPVFFV 1026

		

		

		

		 Score = 93.7 bits (233), Expect = 2e-21

		 Identities = 63/375 (16%), Positives = 126/375 (33%), Gaps = 22/375 (5%)

		

		Query: 662  LELTTLDRNKDELNDTAAK-VQKLLEDYPGLNNVGNSVLRDQLRYDLSIDRNAIILSGVS 720

		                     +D+++D  A  V+  L    G+ +V     +  +R  + +D + +    ++

		Sbjct: 142  FVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMR--IWLDADLLNKYKLT 199

		

		Query: 721  YGDVTNALS-----TFLGSVKAADLHATDGFTYPIQVQVNLDKLSDFKVLNKLYVTSESG 775

		              DV N L         G +              I  Q       +F         +  G

		Sbjct: 200  PVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFG--KVTLRVNSDG 257

		

		Query: 776  QALPLSQFVSIKQTTAESNIK-TFMGLDSAELTADVMPGYST----DEIKAYLDEQLPTL 830

		              + L     ++      N+     G  +A L   +  G +       IKA L E  P  

		Sbjct: 258  SVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFF 317

		

		Query: 831  LNDAQGFKYNGVVKDLMDSQAGTQSLF---LLALVFIYLILAAQFESFVDPLIILLTVPL 887

		                QG K           Q     +      A++ ++L++    ++    LI  + VP+

		Sbjct: 318  ---PQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPV 374

		

		Query: 888  CIVGALLTLTLFGQSVNIYSQIGLLTLVGLVTKHGILLVEFANK-QQDQGLSAIEAARSS 946

		             ++G    L  FG S+N  +  G++  +GL+    I++VE   +   +  L   EA   S

		Sbjct: 375  VLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKS 434

		

		Query: 947  AKSRLRPILMTSLTMILSAIPLALASGPGSLGLANIGLVLVGGLLAGTFFSLFVVPVAYV 1006

		                   ++  ++ +    IP+A   G          + +V  +      +L + P    

		Sbjct: 435  MSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCA 494

		

		Query: 1007 AMAELKAKDVLTRLR 1021

		             + +  + +      

		Sbjct: 495  TLLKPVSAEHHENKG 509

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score =  299 bits (766), Expect = 1e-87

		 Identities = 109/557 (19%), Positives = 219/557 (39%), Gaps = 47/557 (8%)

		

		Query: 143 SDFVGKSGQA-LVDQLSQSTPECVGKLYSLKGSSATALFSEANVISVANAIATKAKDYTG 201

		            D + +   + LV+ +   + E V  L++    S T   +   V ++   +    + YT 

		Sbjct: 95  FDELNRMNYSDLVELIKTISYENVPDLFNFNDGSYTFFSNRDRVQAIIYGLEDSGRTYTA 154

		

		Query: 202 VDVQHLESHIYFVRAALYVQFYSPNDVPAYSSAAKASLKSALNALFANAAIWTVSDDNAG 261

		            D + + + + F+RA  Y+ FY+       +   K     A+ A+  N+     +    G

		Sbjct: 155 DDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNECLPAMKAIQYNSNFRLGTKAQDG 214

		

		Query: 262 VLKEALILIDSAELGADFNHVTIKVLTDYDANWQASFAMNAAANSVFTTLFRAQWNDDMQ 321

		           V++    LI +A    +  +  I VL+D+  N     +  +  N+VF  +    +  +  

		Sbjct: 215 VVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGSNYSKGNAVFNLMKGIDYYTNSV 274

		

		Query: 322 -----ALFARDQGILDALNNFQLE------HRDLLGTNAEYLLVNSVKELSRLYYIDAMR 370

		                   A++    + ++ +           D L  +  +L+ N++    R+      R

		Sbjct: 275 IYNTKGYDAKNTEFYNRIDPYMERLESLCTIGDKLNNDNAWLVNNALYYTGRM---GKFR 331

		

		Query: 371 PRVTQLVKNILSSTSKTEP----SKVLWYAAAEMADYYDRSHCNDYNICGFKAQLEADTL 426

		                + +  L    K  P      +      ++      S  ND +    KA      L

		Sbjct: 332 ED-PSISQRALERAMKEYPYLSYQYIEAANDLDLNFGGKNSSGNDIDFNKIKADAREKYL 390

		

		Query: 427 PFNWKCSDSLKI-RAQD-LYQDQAKWACDVLTSQESYFHSKLETGMQPVGQDNNDDLELV 484

		           P  +   D   + +A D + +++ K         ++ F   ++        + +D L +V

		Sbjct: 391 PKTYTFDDGKFVVKAGDKVTEEKIKRLYWASKEVKAQFMRVVQNDKALEEGNPDDILTVV 450

		

		Query: 485 IFGSSSEYKSLANSIFGINTDNGGMYLEGSPAGLKNQARFIAYEAEWRTPDFHVWNL-QH 543

		           I+ S  EYK L   I G +TDNGG+Y+E       N   F  YE       + +  L +H

		Sbjct: 451 IYNSPEEYK-LNRIINGFSTDNGGIYIE-------NIGTFFTYERTPEESIYTLEELFRH 502

		

		Query: 544 EYVHYLDGRYNLFGDFSRGTS---ANTIWWIEGLAEYIS---------YRDANTAAIAMG 591

		           E+ HYL GRY + G + +G         W+ EG AE+ +          R + T  +A  

		Sbjct: 503 EFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYD 562

		

		Query: 592 ETGEFMLSTIFKNNYESGQDRIYRWGYLAVRFMFEHHRDDVRQILAYLRNDQYAEYQTFM 651

		                 L  +    Y S     Y +G+    +M+ ++     ++  Y++N+  + Y+ ++

		Sbjct: 563 RNNRMSLYGVLHAKYGS--WDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYI 620

		

		Query: 652 DGIGTRY--DNEWQGWL 666

		             + + Y  ++++Q ++

		Sbjct: 621 ASMSSDYGLNDKYQDYM 637

		

		

		

		 Score = 75.1 bits (184), Expect = 1e-15

		 Identities = 36/184 (19%), Positives = 63/184 (34%), Gaps = 26/184 (14%)

		

		Query: 539 WNLQHEYVHYLDGRYNLFGDFSRGTSANTIWWIEGLAEYISYRDANTAAIA-MGETGEFM 597

		           + L  +Y  Y+D   N   +      ++  +     A+ I+    +   ++ + +    +

		Sbjct: 627 YGLNDKYQDYMDSLLNNIDNLDVPLVSD-EYVNGHEAKDINEITNDIKEVSNIKDLSSNV 685

		

		Query: 598 LSTIFKNNYESGQDRIYRWGYLAVRFMFEHH-----RDDVRQILAYLRNDQYAEYQTF-- 650

		             + F   Y+       R  Y+  R   E +        +  IL  L    +  Y+T   

		Sbjct: 686 EKSQFFTTYD------MRGTYVGGRSQGEENDWKDMNSKLNDILKELSKKSWNGYKTVTA 739

		

		Query: 651 ------MDGIGTR-YDNEWQGWLASGLSTADDGIVDKGPSDV-DAEPSGREGNWTGPAGT 702

		                 +DG G   YD  + G       T  D  V+K P  V  ++ S          GT

		Sbjct: 740 YFVNHKVDGNGNYVYDVVFHGMNT---DTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGT 796

		

		Query: 703 ISKD 706

		            SKD

		Sbjct: 797 ESKD 800

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 37.6 bits (87), Expect = 4e-06

		 Identities = 20/105 (19%), Positives = 44/105 (41%), Gaps = 6/105 (5%)

		

		Query: 37  DKEHEIR-LDDKYHCSYLVHYKNTLVGTLKYESTELE-VEIMQVQIHPDHQNKGYGRGII 94

		           D + ++  ++++   ++L + +N  +G +K  S       I  + +  D++ KG G  ++

		Sbjct: 52  DDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALL 111

		

		Query: 95  QQVLNSAQSKI---VSLTVLKDN-PALKLYLRLGFKIVGEDMYEY 135

		            + +  A+      + L     N  A   Y +  F I   D   Y

		Sbjct: 112 HKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLY 156

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 49.1 bits (117), Expect = 2e-10

		 Identities = 17/22 (77%), Positives = 18/22 (81%)

		

		Query: 2   SNKVGRNDLCPCGSGKKYKKCC 23

		             KVGRND CPCGSGKKYK+C 

		Sbjct: 876 ERKVGRNDPCPCGSGKKYKQCH 897

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 39.4 bits (92), Expect = 9e-05

		 Identities = 29/204 (14%), Positives = 69/204 (33%), Gaps = 6/204 (2%)

		

		Query: 42  QLDELKQQQEAIKAIDSLSAAIKKGERNYVDNAQALDKLKQEQKQATAEAKKLEQAQKEA 101

		           +L  L  + + +K   SL  A  +  R  +  +++++  K  + +   E      +++E 

		Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQIL-SRSIELNKLPELKLPDEPYFQNVSEEEV 184

		

		Query: 102 ATSTSKLETQYSQTVAELSQYDAQLATARAEVERLTATQDKGAQASKEQAQALSKAKNDL 161

		              TS ++ Q+S    +  Q +  L   RAE   + A         +  ++      +D 

		Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR----INRYENLSRVEKSRLDDF 240

		

		Query: 162 QQLETAQINTANSASKLATELDQERIGLDKLGDEVEKASRSKAEYALKVKGARTEL-NQL 220

		             L   Q    ++  +   +  +    L     ++E+          + +       N++

		Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300

		

		Query: 221 GSSLGRNKAELDKQQTVLNKAGID 244

		              L +    +      L K    

		Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEER 324

		

		

		

		 Score = 33.3 bits (76), Expect = 0.008

		 Identities = 28/163 (17%), Positives = 52/163 (31%), Gaps = 10/163 (6%)

		

		Query: 18  FSSEAKKSEQALQELGRESEKLNEQLDELKQQQEAIK-AIDSLSAAIKKGERNYVDNAQA 76

		              E      + +E+ R +  + EQ    + Q+   +  +D   A               

		Sbjct: 170 LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR----INR 225

		

		Query: 77  LDKLKQEQKQATAEAKKLEQAQKEAATSTSKLETQYSQTVAELSQYDAQLATARAEV--- 133

		            + L + +K    +   L   Q  A  +  + E +Y + V EL  Y +QL    +E+   

		Sbjct: 226 YENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285

		

		Query: 134 --ERLTATQDKGAQASKEQAQALSKAKNDLQQLETAQINTANS 174

		             E    TQ    +   +  Q          +L   +     S

		Sbjct: 286 KEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQAS 328

		

		

		>BCTERIALGSPD#Bacterial general secretion pathway protein D

		           signature.

		          Length = 660

		

		 Score = 31.8 bits (72), Expect = 0.021

		 Identities = 13/67 (19%), Positives = 30/67 (44%), Gaps = 5/67 (7%)

		

		Query: 354 AGLEPLTIDAQSLFVNVGERTN---VTGSAKFLKLIKEGKFEQALDVAREQVESGAQIID 410

		              +P+    +++ +    +TN   VT +   +  ++  +    LD+ R QV   A I +

		Sbjct: 298 QAAKPVAALDKNIIIKAHGQTNALIVTAAPDVMNDLE--RVIAQLDIRRPQVLVEAIIAE 355

		

		Query: 411 INMDEGM 417

		           +   +G+

		Sbjct: 356 VQDADGL 362

		

		

		>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature.

		          Length = 296

		

		 Score = 39.5 bits (92), Expect = 7e-06

		 Identities = 43/180 (23%), Positives = 66/180 (36%), Gaps = 16/180 (8%)

		

		Query: 18  PHGVLADPAKRIIALSPHAVEMLYAIGAGDAIVAATDYADY------PEAAKKIPRIGGY 71

		            H    DP  RI+AL    VE+L A+G     VA  D  +Y      P     +  +G  

		Sbjct: 28  AHAAAIDP-NRIVALEWLPVELLLALGIVPYGVA--DTINYRLWVSEPPLPDSVIDVGLR 84

		

		Query: 72  YGIQMERVMELNPDLIVVWDTGNKA--EDINQL-RTLGFNLYGSDPKTLEGVANELEELG 128

		               +E + E+ P  + VW  G     E + ++    GFN +    + L      L E+ 

		Sbjct: 85  TEPNLELLTEMKPSFM-VWSAGYGPSPEMLARIAPGRGFN-FSDGKQPLAMARKSLTEMA 142

		

		Query: 129 KLTGHVEEASKAAAAYRAELIRLRTDNASKSE-PKVFYQLWSTPLMTV-SKNSWIQQIIS 186

		            L      A    A Y   +  ++     +   P +   L     M V   NS  Q+I+ 

		Sbjct: 143 DLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILD 202

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 31.8 bits (72), Expect = 7e-04

		 Identities = 10/24 (41%), Positives = 18/24 (75%), Gaps = 2/24 (8%)

		

		Query: 13 QRGFSLIEVLVALVIL--VIGLIG 34

		          QRGF+L+E++V +VI+  +  L+ 

		Sbjct: 7  QRGFTLLEIMVVIVIIGVLASLVV 30

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 52.2 bits (125), Expect = 1e-11

		 Identities = 25/79 (31%), Positives = 44/79 (55%), Gaps = 4/79 (5%)

		

		Query: 6  KGFTLIEVMITVVIIGILAAIAYPSYTQYIALSARSEGLAALMRIANLQEQYYLDNRVYA 65

		          +GFTL+E+M+ +VIIG+LA++  P+       + + + ++ ++ + N  + Y LDN  Y 

		Sbjct: 8  RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHYP 67

		

		Query: 66 TD---LSKLVGANPYVTEH 81

		          T    L  LV A P +   

		Sbjct: 68 TTNQGLESLVEA-PTLPPL 85

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 35.2 bits (81), Expect = 3e-05

		 Identities = 12/28 (42%), Positives = 20/28 (71%)

		

		Query: 6  KGFTLVELMVTIAVAAILLAIGVPSLTS 33

		          +GFTL+E+MV I +  +L ++ VP+L  

		Sbjct: 8  RGFTLLEIMVVIVIIGVLASLVVPNLMG 35

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 30.6 bits (69), Expect = 0.002

		 Identities = 13/50 (26%), Positives = 30/50 (60%), Gaps = 3/50 (6%)

		

		Query: 5  QKGFSLIELITTLSISTILFTVGTPSFT---DLSDQIRADSNIRTIQQTL 51

		          Q+GF+L+E++  + I  +L ++  P+     + +D+ +A S+I  ++  L

		Sbjct: 7  QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENAL 56

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 34.8 bits (80), Expect = 0.002

		 Identities = 21/89 (23%), Positives = 29/89 (32%), Gaps = 10/89 (11%)

		

		Query: 80  STVDAITAEDIGKFPDKNVAESLQRIPGVTIQRQFGEGAGVSI-----RGAGQDLTLTT- 133

		           S     T +DI  +   NV ++L R+ GV   + FG    + I           LT    

		Sbjct: 144 SDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDV 203

		

		Query: 134 ---LNGQNV-ASTGWFVLEPAKRSFNYEL 158

		              L  QN   + G     PA        

		Sbjct: 204 INQLKVQNDQIAAGQLGGTPALPGQQLNA 232

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 75.0 bits (184), Expect = 1e-18

		 Identities = 29/162 (17%), Positives = 59/162 (36%), Gaps = 6/162 (3%)

		

		Query: 31  SDARQRLITAALSLFSHRSYPTVSTREIAREAEVDAALIRYYFGSKAGLFEQMVRETLEP 90

		            + RQ ++  AL LFS +   + S  EIA+ A V    I ++F  K+ LF ++   +   

		Sbjct: 10  QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69

		

		Query: 91  VLTRLREISAAEAPNN---VGEIMQTYYRVMAPNPGLPRLIIRVLQEGDGSEPYRIILSV 147

		           +     E  A    +    + EI+               L+  +  + +      ++   

		Sbjct: 70  IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129

		

		Query: 148 FEQVLTLSRQWLESTL---VNSGLLKEGVDPDLARLSFVSLM 186

		              +   S   +E TL   + + +L   +    A +     +

		Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 55.6 bits (134), Expect = 1e-10

		 Identities = 32/176 (18%), Positives = 62/176 (35%), Gaps = 17/176 (9%)

		

		Query: 86  TVERDRLTLIAPVGELITQVNVVEGQQVKAGEVLLTLDSTSANARLALRQAELEQAKAKL 145

		           T       +      ++ ++ V EG+ V+ G+VLL L +  A A     Q+ L Q  A+L

		Sbjct: 91  THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ--ARL 148

		

		Query: 146 SEAVTGARLEDIERAKAVLDGANASVKEAQRAFERTNRLYATKVLSQADLDTARAARDTS 205

		            +         IE      +         +  F+  +     +VL    L   +    T 

		Sbjct: 149 EQTRYQILSRSIEL-----NKLPELKLPDEPYFQNVS---EEEVLRLTSL--IKEQFSTW 198

		

		Query: 206 LAKQAEAEQSLRLLENGTRSEQLEQAKAAVAAASASVAIEQKALADLSLVAARDAV 261

		             ++ + E +L       +  +     A +        +E+  L D S +  + A+

		Sbjct: 199 QNQKYQKELNLD-----KKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAI 249

		

		

		

		 Score = 51.0 bits (122), Expect = 3e-09

		 Identities = 34/258 (13%), Positives = 87/258 (33%), Gaps = 17/258 (6%)

		

		Query: 82  SVLGTVERDRLTLIAPVGELITQVNVVEGQQVKAGEVLLTLDSTSANARLALRQAELEQA 141

		            +  ++E ++L  +    E   Q   V  ++V     L+    ++   +   ++  L++ 

		Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQN--VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212

		

		Query: 142 KAKLSEAVTGARLEDIERAKAVLDGANASVKE-AQRAFERTNRLYATK---VLSQADLDT 197

		           +A+    +  AR+   E    V             +     + +   +   V +  +L  

		Sbjct: 213 RAERLTVL--ARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRV 270

		

		Query: 198 ARAARDTSLAKQAEAEQSLRLLENGTRSEQLEQAKAAVAAASASVAIEQKALADLS---L 254

		            ++  +   ++   A++  +L+    ++E L++ +              K         +

		Sbjct: 271 YKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVI 330

		

		Query: 255 VAARDAVVDTLP-WRVGDRIAAGTQLIGLLASEDPY-VRVYLPATWLDRVKAGDKVNIRV 312

		            A     V  L     G  +     L+ ++  +D   V   +    +  +  G    I+V

		Sbjct: 331 RAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKV 390

		

		Query: 313 D---GREIP-IAGTVRNI 326

		           +         + G V+NI

		Sbjct: 391 EAFPYTRYGYLVGKVKNI 408

		

		

		>adhesinb#Adhesin B signature.

		          Length = 310

		

		 Score = 29.4 bits (66), Expect = 0.018

		 Identities = 15/87 (17%), Positives = 26/87 (29%), Gaps = 12/87 (13%)

		

		Query: 220 SPQQLMAAMGARVVEISGDDL------------RNLKQSLISESAVLSAAQIGSRLRVLV 267

		            P+ +     A ++  +G +L             N K+    +   +S       L    

		Sbjct: 73  LPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQS 132

		

		Query: 268 RSDIEDPLAWLKPRVASRTMEEVRASL 294

		               EDP AWL         + +   L

		Sbjct: 133 EKGKEDPHAWLNLENGIIYAQNIAKRL 159

		

		

		>ABC2TRNSPORT#ABC-2 type transport system membrane protein

		           signature.

		          Length = 262

		

		 Score = 39.9 bits (93), Expect = 7e-06

		 Identities = 48/200 (24%), Positives = 91/200 (45%), Gaps = 24/200 (12%)

		

		Query: 186 GVILTMTMVMFT----SAAIVREREQGNMEFLITTPVRPLELMLGKI--------VPYVI 233

		           G++ T  M   T     AA  R   Q   E ++ T +R  +++LG++        +    

		Sbjct: 72  GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131

		

		Query: 234 VGFVQVTIILSAG-HLLFDVPIRGGIDSIALAAMLFICASLTLGLVISTIAKTQLQSMQM 292

		           +G V   +  +    LL+ +P+      IAL  + F     +LG+V++ +A +    +  

		Sbjct: 132 IGVVAAALGYTQWLSLLYALPV------IALTGLAFA----SLGMVVTALAPSYDYFIFY 181

		

		Query: 293 TVFILLPSILLSGFMFPYEAMPIAAQWIAEALPATHFMRMSRAIVLRDAQVMDLQFDALW 352

		              ++ P + LSG +FP + +PI  Q  A  LP +H + + R I+L    V+D+      

		Sbjct: 182 QTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIML-GHPVVDVCQHVGA 240

		

		Query: 353 MIGFTCIGLFIASMRFSKRL 372

		           +  +  I  F+++    +RL

		Sbjct: 241 LCIYIVIPFFLSTALLRRRL 260

		

		

		>BLACTAMASEA#Beta-lactamase class A signature.

		          Length = 286

		

		 Score = 28.6 bits (64), Expect = 0.046

		 Identities = 9/27 (33%), Positives = 12/27 (44%)

		

		Query: 114 FQAASISKSLTAMAALQLVEQGKLQLD 140

		           F   S  K +   A L  V+ G  QL+

		Sbjct: 62  FPMMSTFKVVLCGAVLARVDAGDEQLE 88

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 28.6 bits (64), Expect = 0.050

		 Identities = 11/32 (34%), Positives = 20/32 (62%)

		

		Query: 352 LAAYITHFGDAQQCANALFIHRNTLRYRLDKI 383

		           LAA     G+  + A+ L ++RNTLR ++ ++

		Sbjct: 442 LAALTATRGNQIKAADLLGLNRNTLRKKIREL 473

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 30.2 bits (68), Expect = 0.017

		 Identities = 15/70 (21%), Positives = 29/70 (41%), Gaps = 13/70 (18%)

		

		Query: 64  KLPTPHELRAHLDDYVIGQDRAKKVLSVAVYNHYKRLKNASPKDGIELGKSNILLIGPTG 123

		           + P+  E  +     ++G+       S A+   Y+ L      D        +++ G +G

		Sbjct: 124 RRPSKLEDDSQDGMPLVGR-------SAAMQEIYRVLARLMQTD------LTLMITGESG 170

		

		Query: 124 SGKTLLAETL 133

		           +GK L+A  L

		Sbjct: 171 TGKELVARAL 180

		

		

		>ECOLIPORIN#E.coli/Salmonella-type porin signature.

		          Length = 383

		

		 Score = 70.7 bits (173), Expect = 2e-15

		 Identities = 99/417 (23%), Positives = 165/417 (39%), Gaps = 52/417 (12%)

		

		Query: 1   MNKTLVATALAAIFLVPSVSAIEIYKDNKNAVEIGGFIDARVINTQGETEVVNG-ASRIN 59

		           M + ++A  + A+    +  A EIY  + N +++ G +D     +   ++  +G  + + 

		Sbjct: 1   MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSK--DGDQTYMR 58

		

		Query: 60  FGFNRE--LTDGWKAFAKLEWGVNPVGSSDIVYNNRFESVQEEFFYNRLGYAGLSHDTYG 117

		            GF  E  + D    + + E+ V           N  E      +  RL +AGL    YG

		Sbjct: 59  VGFKGETQINDQLTGYGQWEYNVQ---------ANTTEGEGANSW-TRLAFAGLKFGDYG 108

		

		Query: 118 TLTIGKQWGAWYDVVYNTNYGFVWDGNTAGVYTYNKDDGAVNGVGRGDKTVQYRNA--FG 175

		           +   G+ +G  YDV   T+    + G++   Y  N   G  NGV        YRN   FG

		Sbjct: 109 SFDYGRNYGVLYDVEGWTDMLPEFGGDSYT-YADNYMTGRANGV------ATYRNTDFFG 161

		

		Query: 176 DV---SFAVQAQLKNS--SFYTCDTTDDITQAQCQANWESGDKAAQQVEYNYTYGGALTY 230

		            V   +FA+Q Q KN   S    +   +         +++GD       Y+   G +   

		Sbjct: 162 LVDGLNFALQYQGKNESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGA 221

		

		Query: 231 KVTDMLTLTAGVNRGEFDVSFGNGEQTTAVDLIYGAGITWGNFDNDGLYAAA------NV 284

		             T        VN G    +   G++  A    + AG+    +D + +Y A       N+

		Sbjct: 222 AYTTSDRTNEQVNAG---GTIAGGDKADA----WTAGL---KYDANNIYLATMYSETRNM 271

		

		Query: 285 NRQENHDTDNIGRLIKDAYGIESLVSYKFDNGLRPFISYNVLDAGKDYVIQPNFNADPND 344

		                 D    G +       E    Y+FD GLRP +S+ ++  GKD +   N N D  D

		Sbjct: 272 TPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSF-LMSKGKD-LTYNNVNGDDKD 329

		

		Query: 345 EFKRQFLVVGLHFVWDPNTVLYIEARKDYSDFTSADKDQEARMALSESDGVAIGIRY 401

		             K  +  VG  + ++ N   Y++ + +  D    D        +S  D VA+G+ Y

		Sbjct: 330 LVK--YADVGATYYFNKNFSTYVDYKINLLD---DDDPFYKDAGISTDDIVALGMVY 381

		

		

		>PF03544#Gram-negative bacterial tonB protein

		          Length = 243

		

		 Score =  101 bits (254), Expect = 7e-29

		 Identities = 35/169 (20%), Positives = 64/169 (37%), Gaps = 11/169 (6%)

		

		Query: 39  TPVIEITMDRQDSKAQNKPRVVPKPPPPPEQPQKPDTTPPDSSSNID----TSMSFNMGG 94

		            P  E     +  K        PKP P P+         P            S   N   

		Sbjct: 75  EPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAP 134

		

		Query: 95  VEAGGASTG-FKLGNMMTRDGDATPIVRIEPQYPIAAARDGKEGWVQLRFTINELGGIDD 153

		                ++        + +       + R +PQYP  A     EG V+++F +   G +D+

		Sbjct: 135 ARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDN 194

		

		Query: 154 VEVIQAEPKRLFDKEAIRALKKWKYKPKIVDGKPLKQPGQTVQLDFTLD 202

		           V+++ A+P  +F++E   A+++W+Y+P           G  V + F ++

		Sbjct: 195 VQILSAKPANMFEREVKNAMRRWRYEP------GKPGSGIVVNILFKIN 237

		

		

		>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD

		           chaperone signature.

		          Length = 168

		

		 Score = 29.9 bits (67), Expect = 0.011

		 Identities = 11/52 (21%), Positives = 21/52 (40%)

		

		Query: 197 AYFNQKKYKKAVGVLEVMVPLFPEDGRLWVQLAQFYLMVEDYDKSLATYDLA 248

		             +   KY+ A  V + +  L   D R ++ L      +  YD ++ +Y   

		Sbjct: 45  NQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYG 96

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 49.3 bits (117), Expect = 8e-08

		 Identities = 48/306 (15%), Positives = 104/306 (33%), Gaps = 14/306 (4%)

		

		Query: 198  AADISALVKDQRSRRDGILQSAGLASDDELSNELAKLTPELALA--QSAKEQALQQQQLI 255

		              +I A V    S  + I +              ++ T  +A    Q +K     +Q   

		Sbjct: 1000 PNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDAT 1059

		

		Query: 256  IKASDAAQHLLAEFAQFDTLTQTAAALEAQQESIVAQTHKLNLAEQAQRLAPMIEVFLAR 315

		               +   +      +     TQT    ++  E+   QT +    ++   +    +  +  

		Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE---TKETATVEKEEKAKVET 1116

		

		Query: 316  EQEAKAANLAFSHAQTALTQAKQAFDDAELKAQDLPVLEASLLEQEQAKQQLNALGPQL- 374

		            E+  +   +  S       Q++     AE   ++ P +     ++ Q++    A   Q  

		Sbjct: 1117 EKTQEVPKVT-SQVSPKQEQSETVQPQAEPARENDPTVNI---KEPQSQTNTTADTEQPA 1172

		

		Query: 375  RELDRLNKTLEQEQAQLVKAKTQLQISKNELTAASQKRRELESALPQLQANSDTRLTLQQ 434

		            +E     +    E   +    + ++  +N   A +Q     ES+      N   R     

		Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESS--NKPKNRHRRSVRSV 1230

		

		Query: 435  AHQQQQQLLSTYQQWQQVAARVSS--TKAKLANAKAQGQQLNAEHQQAQVAHKALLITWH 492

		             H  +    S+  +       ++S  T A L++A+A+ Q +     +A   H + L   +

		Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNN 1290

		

		Query: 493  QGQAAI 498

		            +GQ  +

		Sbjct: 1291 EGQYNV 1296

		

		

		

		 Score = 43.9 bits (103), Expect = 4e-06

		 Identities = 49/325 (15%), Positives = 95/325 (29%), Gaps = 32/325 (9%)

		

		Query: 277  QTAAALEAQQESIVAQTHKLNLAEQAQRLAPMIEVFLAREQEAKAANLAFSHAQTALTQA 336

		                 +    E+ V        +E  + +A         +QE+K        A     Q 

		Sbjct: 1012 SNNEEIARVDEAPVPPPAPATPSETTETVA------ENSKQESKTVEKNEQDATETTAQN 1065

		

		Query: 337  KQAFDDAELKAQDLPVLEASLLEQEQAKQQLNALGPQLRELDRLNKTLEQEQAQLVKAKT 396

		            ++   +A+        ++A+    E A+        Q  E        ++E+A++   KT

		Sbjct: 1066 REVAKEAK------SNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119

		

		Query: 397  QLQISKNELTAASQKRRELESALPQLQANSDTRLTLQQAHQQQQQLLSTYQQWQQVAARV 456

		            Q         +  Q++ E      +    +D  + +++   Q      T    +Q A   

		Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT----EQPAKET 1175

		

		Query: 457  SSTKAKLANAKAQGQQLNAEHQQAQVAHKALLITWHQGQAAILARQLQQDEPCPVCGSQI 516

		            SS   +           N+  +  +    A                   ++P       +

		Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPA--------TTQPTVNSESSNKPKNRHRRSV 1227

		

		Query: 517  HPQPAQSQEPL---PSDEALQLAQDAETTAQEVLSKARA--EYRGLQTQLETLQQQAQ-- 569

		               P   +           + L     T    VLS ARA  ++  L       Q  +Q  

		Sbjct: 1228 RSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLE 1287

		

		Query: 570  -DLAAQLGTAVDISQDQHAHTLSQY 593

		             +   Q    V  +     ++ SQY

		Sbjct: 1288 MNNEGQYNVWVSNTSMNKNYSSSQY 1312

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 54.7 bits (131), Expect = 2e-09

		 Identities = 58/393 (14%), Positives = 103/393 (26%), Gaps = 63/393 (16%)

		

		Query: 516  YK-RIEQPEAKLYEPR--KLERTAAPIPALKGFAAPQKVEQAPSPTVKVEAPQPGFFSKL 572

		            YK R       LY P   K  +T                 QA  P+V     +     + 

		Sbjct: 969  YKLRNVNGRYDLYNPEVEKRNQTVDTTNI-----TTPNNIQADVPSVPSNNEEIARVDEA 1023

		

		Query: 573  VSAISAMFAPSEKAEPV--------KVVETKTTDTSAANANRRNRR-------------- 610

		                 A   PSE  E V        K VE    D  A     +NR               

		Sbjct: 1024 PVPPPAPATPSETTETVAENSKQESKTVEKNEQD--ATETTAQNREVAKEAKSNVKANTQ 1081

		

		Query: 611  -----------NDTRRPRNAQDADKAKEGTREPRSRNSKKPADAAVNTSAQERPVREKEE 659

		                        +T+     + A   KE   +  +  +++         +Q  P +E+ E

		Sbjct: 1082 TNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVT----SQVSPKQEQSE 1137

		

		Query: 660  TKRPARSEPKPRVQAPKDVVADVEADAPKQEVARERRQRRNMRRKVRIDNGHNTPDNAIP 719

		            T +P  +EP          V   E  +     A   +  +     V      +T  N   

		Sbjct: 1138 TVQPQ-AEPARE---NDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGN 1193

		

		Query: 720  IAPEDAAEVLAEIAAVNAAAASTISVDTKTEV-VQAPTETKAPRTRRQPRKEAAPAQEAA 778

		               E+              + S+     +    V++      P T     +      +  

		Sbjct: 1194 SVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLT 1253

		

		Query: 779  ENVAVEEKAVSSAVTETPAVDAVKTEEQAEVVTADVTAPMDAISQDNDAIDTESETADDQ 838

		                    + + A  +  A++          V   V+  +  +  +N+        ++  

		Sbjct: 1254 STNTNAVLSDARAKAQFVALN----------VGKAVSQHISQLEMNNEG-QYNVWVSNTS 1302

		

		Query: 839  AKREQRDGQRRSRRSPRHLRAAGQRRRRDEDDQ 871

		              +     Q R   S       G  +    + Q

		Sbjct: 1303 MNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQ 1335

		

		

		

		 Score = 48.5 bits (115), Expect = 1e-07

		 Identities = 61/338 (18%), Positives = 107/338 (31%), Gaps = 42/338 (12%)

		

		Query: 761  PRTRRQPRKEAAPAQEAAENVAVEEKAVSSAVTETPAVDAVKTEEQAEVVTADVTAPMDA 820

		            P   ++ +           N+  +  +V S             EE A V  A V  P  A

		Sbjct: 983  PEVEKRNQTVDTTNITTPNNIQADVPSVPS-----------NNEEIARVDEAPVPPPAPA 1031

		

		Query: 821  ISQDNDAIDTESETADDQAKREQRDGQRRSRRSPRHLRAAGQRRRRDEDDQGTSTPAQFI 880

		               +    +T +E +  ++K  +++ Q  +  + ++   A + +   + +  T+      

		Sbjct: 1032 TPSETT--ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN------ 1083

		

		Query: 881  PNDELGANQEYPSEVASVRVEAPVVATKTDAVTETQVTAKSVEVDMAQASEAPVVEAPAV 940

		                         EVA    E     T     T T    +  +V+  +  E P V +   

		Sbjct: 1084 -------------EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVS 1130

		

		Query: 941  VKAETKVETSANDVTAVETQEVETKPVETKATEADAPKTVEVKIDVAPVVEAPVASVAVE 1000

		             K E + ET           +      E ++       T +   + +  VE PV      

		Sbjct: 1131 PKQE-QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTT- 1188

		

		Query: 1001 TEVGNAPVVESPAVTPAA--PKVEAAKVEVAKTETAVE-PSVAPSVEVKEAIKAAASAPM 1057

		               GN+ V      TPA   P V +      K        SV  +VE      A  S+  

		Sbjct: 1189 VNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE-----PATTSSND 1243

		

		Query: 1058 AKPAAIAKPQATVQVAPTTVNPQITDALVVNKPKAASR 1095

		                A+    +T   A  +        + +N  KA S+

		Sbjct: 1244 RSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQ 1281

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 40.7 bits (95), Expect = 5e-07

		 Identities = 20/57 (35%), Positives = 30/57 (52%)

		

		Query: 80  LILNDVYVTQHARCVGIGRALVQQAASYAKAHNMSYLMLETQQKNQRAQGLYEGLGF 136

		            ++ D+ V +  R  G+G AL+ +A  +AK ++   LMLETQ  N  A   Y    F

		Sbjct: 90  ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 76.3 bits (187), Expect = 4e-16

		 Identities = 34/128 (26%), Positives = 60/128 (46%), Gaps = 9/128 (7%)

		

		Query: 784 APVASFTQVVNGAAVQLTST-STDSDGQIVSAEWSFGDNTVAVGEVVTHSYSQSGEYLVT 842

		           A + S + V+    +    T S D DG+I + EW FGD   +     TH Y+++GEY V 

		Sbjct: 777 AVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVK 836

		

		Query: 843 LTVTDNDGLTHSTSQTVSVVVGEVKQP------PVAQIQRINLLF-VDMFISTSYDTDGV 895

		           LTVTDN+G  ++ S+ +  VV +          P    ++ N +   +M +  +   +  

		Sbjct: 837 LTVTDNNGGINTESKKI-KVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDY 895

		

		Query: 896 IKQHKWTF 903

		             ++ +  

		Sbjct: 896 SDKYYFDV 903

		

		

		

		 Score = 40.5 bits (94), Expect = 4e-05

		 Identities = 18/55 (32%), Positives = 32/55 (58%), Gaps = 1/55 (1%)

		

		Query: 889 SYDTDGVIKQHKWTFDNGTRAN-GQVVLRLARRGQHTVELTVKDNDKLTDTTTLT 942

		           S D DG IK ++W F +G ++N  +   +  + G++ V+LTV DN+   +T +  

		Sbjct: 798 SKDEDGEIKAYEWDFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKK 852

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score = 31.3 bits (71), Expect = 0.010

		 Identities = 16/36 (44%), Positives = 23/36 (63%)

		

		Query: 158 NLVIDIGGGSTEVVIGKKNTPTQLSSLRCGCVSFNE 193

		           ++V+DIGGG+TEV +   N     SS+R G   F+E

		Sbjct: 161 SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDE 196

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score = 41.3 bits (97), Expect = 7e-06

		 Identities = 24/81 (29%), Positives = 42/81 (51%), Gaps = 11/81 (13%)

		

		Query: 192 AAKRAGFVDVDFLFEPLAAGMDYEATLTDNKTVLVVDVGGGTTDCSVVKMGPAHKQKADR 251

		           +A+ AG  +V  + EP+AA +     +++    +VVD+GGGTT+ +V+ +          

		Sbjct: 129 SAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN--------- 179

		

		Query: 252 SEDFLGHSGQRIGGNDLDIAL 272

		               +  S  RIGG+  D A+

		Sbjct: 180 --GVVYSSSVRIGGDRFDEAI 198

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		           signature.

		          Length = 145

		

		 Score = 29.5 bits (66), Expect = 0.007

		 Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 8/78 (10%)

		

		Query: 142 IVIISVFIVIVTSFFYAKQDKVIAPESALAQQLMVVVNGIEKYRLENNKTP---EKLSDL 198

		           IVII V   +V       ++K    + A++  ++ + N ++ Y+L+N+  P   + L  L

		Sbjct: 19  IVIIGVLASLVVPNLMGNKEKADK-QKAVSD-IVALENALDMYKLDNHHYPTTNQGLESL 76

		

		Query: 199 LEFPR---EAVEWRIDQY 213

		           +E P     A  +  + Y

		Sbjct: 77  VEAPTLPPLAANYNKEGY 94

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		           signature.

		          Length = 145

		

		 Score = 45.3 bits (107), Expect = 5e-08

		 Identities = 28/98 (28%), Positives = 43/98 (43%), Gaps = 5/98 (5%)

		

		Query: 7   RKNNNRGFNLLEIMVVVAIIGILAVVAVPLYKDYIIRAQVTEAFVFADAERIKVIEKRIE 66

		             +  RGF LLEIMVV+ IIG+LA + VP       +A   +A        I  +E  ++

		Sbjct: 3   ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKA-----VSDIVALENALD 57

		

		Query: 67  STNVDIATFSEPKVHMTSLMWVPVINNQPVENSVIGYI 104

		              +D   +      + SL+  P +       +  GYI

		Sbjct: 58  MYKLDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYI 95

		

		

		>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature.

		          Length = 591

		

		 Score = 31.3 bits (70), Expect = 0.016

		 Identities = 24/89 (26%), Positives = 45/89 (50%), Gaps = 12/89 (13%)

		

		Query: 604 SEILKKDTSVIAILIDSALMQSTPAEWLGKLREQLAWSGTPVLFLIPPNQNETKILLNKF 663

		           S++LK+ T++  I+ID A M ++P +         AW    +L +     ++ +IL +  

		Sbjct: 481 SDVLKEYTTIGNIIIDKAFMSTSPDK---------AWINDTILNIYLEKGHKGRILGDV- 530

		

		Query: 664 HAHAMEYDENMTPPTEIVNKLQSILTKGT 692

		            AH     E + PP   + K++SI+  G+

		Sbjct: 531 -AHFKGEAEMLFPPNTKL-KIESIVNCGS 557

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score = 39.0 bits (91), Expect = 7e-05

		 Identities = 13/27 (48%), Positives = 21/27 (77%)

		

		Query: 654 TLHPAMQHNIGDKLGSLEKGKLADMVV 680

		           T++PA+ H +  ++GSLE GK AD+V+

		Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLVL 436

		

		

		>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature.

		          Length = 1291

		

		 Score = 27.7 bits (61), Expect = 0.008

		 Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 2/45 (4%)

		

		Query: 21  QEYLKERLGVDGYNNCNRWDTLKMQGGFTPKKCDCCVGEDGANKN 65

		            E  KERL +  YNN NR D   ++     K C   +G      N

		Sbjct: 755 IEQFKERLAL--YNNNNRMDICVVRNTDDIKACGTAIGNQSMVNN 797

		

		

		>PERTACTIN#Pertactin signature.

		          Length = 922

		

		 Score = 28.9 bits (64), Expect = 0.025

		 Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 3/60 (5%)

		

		Query: 173 NVIESAEGNWLAFKFDEPANALSLEGMHGSGDSGGASVIFEDSIPFLVGLSSWQLGHGDI 232

		           NVIE+  G   A +F  PA+ LS+    G+   G A +      P  + L+    G GDI

		Sbjct: 337 NVIETGGG---ARRFPPPASPLSITLQAGARAQGRALLYRVLPEPVKLTLAGGAQGQGDI 393

		

		

		>TYPE3OMBPROT#Type III secretion system outer membrane B protein

		           family signature.

		          Length = 538

		

		 Score = 26.6 bits (58), Expect = 0.018

		 Identities = 16/52 (30%), Positives = 24/52 (46%)

		

		Query: 12  RLVVLRLLTEAGAFALNESILQDGLNAYGLDISRDALLVQLAWLNEQGLIKT 63

		           ++V   LLT        ES+L+D +NA     S+     +L   N  GL+K 

		Sbjct: 275 KIVSTSLLTPTSLTGGEESMLKDQVNALKGLNSKRGEPTKLLIRNSDGLLKE 326

		

		

		>OMS28PORIN#OMS28 porin signature.

		          Length = 257

		

		 Score = 28.2 bits (62), Expect = 0.033

		 Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 9/65 (13%)

		

		Query: 97  SLSRKELALTRQELA---ETKEETALSRRAMEAQVEHLQKEAKLNEITRLINDLKIKINV 153

		           S + KEL LT++E A   + KE    S RA++  V+  QK      +  ++N L      

		Sbjct: 168 SPNNKELELTKEEFAKVEQVKETLMASERALDETVQEAQK------VLNMVNGLNPSNKD 221

		

		Query: 154 QLSAK 158

		           Q+ AK

		Sbjct: 222 QVLAK 226

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 46.6 bits (110), Expect = 6e-07

		 Identities = 48/383 (12%), Positives = 118/383 (30%), Gaps = 3/383 (0%)

		

		Query: 830  TGAAVPETLKAQAATLGLTKELSELTAKQYGYTDSVKELSPEQAKLSRAVAETEARLKQC 889

		             G  V     +  AT   T  L ++  +   +      L  + + LS      +    + 

		Sbjct: 31   AGLVVNTNEVSAVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDEL 90

		

		Query: 890  RDVMNSSTVSSKAKAKAQQDLISLQGKLSDQTKQLSEVQALEAANYEQIKSKYAAVSDEM 949

		             + ++++    +   K+  +  S   +L  +   L +             +K   +  E 

		Sbjct: 91   TEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEK 150

		

		Query: 950  LRLEQAYKDGGITAEEYLRQKERLVEVLRILQRLMGGLEDGEQETDEQVKKTTKTLIEQR 1009

		              L     D     E  +         ++ L+     LE  + E ++ ++          

		Sbjct: 151  AALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADS 210

		

		Query: 1010 EELEQLEETTGRATEYVNLFAGAYAHLNKQFNFNEDSTEKLNARVDELTKSIMNNMRVNT 1069

		             +++ LE               A          +    + L A    L        +   

		Sbjct: 211  AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALE 270

		

		Query: 1070 GFWGVLAQLSNQAFIREKQIINETLLTRKWTEELESSSISLDRVNQISREAKWNIRELGD 1129

		            G        S +    E +             + +  + +   + +    ++   ++L +

		Sbjct: 271  GAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQL-E 329

		

		Query: 1130 EELKPLQAAIDATRDRILGLRDDINATLDSLKDEMDQLNNNQAAIEKRRYEQQQAELKAQ 1189

		             E + L+     +      LR D++A+ ++ K    +    +   + +  E  +  L+  

		Sbjct: 330  AEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQ--KLEEQNKISEASRQSLRRD 387

		

		Query: 1190 LDAARTAQDKESIASAQEALQLS 1212

		            LDA+R A+ +   A  +   +L+

		Sbjct: 388  LDASREAKKQVEKALEEANSKLA 410

		

		

		

		 Score = 37.4 bits (86), Expect = 4e-04

		 Identities = 52/320 (16%), Positives = 106/320 (33%), Gaps = 7/320 (2%)

		

		Query: 740  DQYEGHVKLLTLLRAKFEEQQTYLDATAKGAEALEQAYKDLGLTSSHALEQVNTKAEAAF 799

		            D++E     L L  +        L              K+    +  +L +  +K +   

		Sbjct: 60   DKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELE 119

		

		Query: 800  NLIKNNREPIEQQKDAFLAWAKAALTAAEATGAAVPETLKAQAATLGLTKELSELTAKQY 859

		                +  + +E     F     A +   EA      E     A    L K L        

		Sbjct: 120  ARKADLEKALEGA-MNFSTADSAKIKTLEA------EKAALAARKADLEKALEGAMNFST 172

		

		Query: 860  GYTDSVKELSPEQAKLSRAVAETEARLKQCRDVMNSSTVSSKAKAKAQQDLISLQGKLSD 919

		              +  +K L  E+A L    AE E  L+   +   + +   K     +  L + +  L  

		Sbjct: 173  ADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEK 232

		

		Query: 920  QTKQLSEVQALEAANYEQIKSKYAAVSDEMLRLEQAYKDGGITAEEYLRQKERLVEVLRI 979

		              +        ++A  + ++++ AA+      LE+A +     +     + + L      

		Sbjct: 233  ALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAA 292

		

		Query: 980  LQRLMGGLEDGEQETDEQVKKTTKTLIEQREELEQLEETTGRATEYVNLFAGAYAHLNKQ 1039

		            L+     LE   Q  +   +   + L   RE  +QLE    +  E   +   +   L + 

		Sbjct: 293  LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352

		

		Query: 1040 FNFNEDSTEKLNARVDELTK 1059

		             + + ++ ++L A   +L +

		Sbjct: 353  LDASREAKKQLEAEHQKLEE 372

		

		

		>PF07472#Fucose-binding lectin II

		          Length = 245

		

		 Score = 28.5 bits (63), Expect = 0.006

		 Identities = 19/76 (25%), Positives = 26/76 (34%), Gaps = 8/76 (10%)

		

		Query: 6   TLQLPHFIWLNRFGYTPFVSSTEFALDGSQHVEVAAKQAGRPVVLFSDAETLAVFNALEA 65

		              LP  I    FG T  V+S        Q +EV      +P   F  A T       + 

		Sbjct: 135 IFNLPPNI---AFGVTALVNS-----SAQQTIEVYVDDNPKPAATFQGAGTQDANLNTQI 186

		

		Query: 66  HANSKGAISFNLDING 81

		             + KG +   +  NG

		Sbjct: 187 VNSGKGKVRVVVTANG 202