PredictBias

		>DPTHRIATOXIN#Diphtheria toxin signature.

		          Length = 567

		

		 Score = 28.6 bits (63), Expect = 0.050

		 Identities = 20/73 (27%), Positives = 35/73 (47%), Gaps = 5/73 (6%)

		

		Query: 104 SSRGATESFEKFYQTFLETG-----KTPTLTSPLTTLGNISTWVLQDLGITGPDFSHSIT 158

		           S   A +  E+F+QT LE       KT T T+P+    N + W +    +   + + ++ 

		Sbjct: 271 SEEKAKQYLEEFHQTALEHPELSELKTVTGTNPVFAGANYAAWAVNVAQVIDSETADNLE 330

		

		Query: 159 CSTALHSVVNGIA 171

		            +TA  S++ GI 

		Sbjct: 331 KTTAALSILPGIG 343

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 59.1 bits (143), Expect = 2e-12

		 Identities = 28/140 (20%), Positives = 61/140 (43%), Gaps = 9/140 (6%)

		

		Query: 4   KISCLVLDDEPLGRTIIENFVKQVPFLELSASFDDALEAITFLQKNQVEIIFSDIEMPRI 63

		             + LV DD+   RT++   + +  +     S  +A     ++     +++ +D+ MP  

		Sbjct: 3   GATILVADDDAAIRTVLNQALSRAGYDVRITS--NAATLWRWIAAGDGDLVVTDVVMPDE 60

		

		Query: 64  NGIELINLL----DNPPIIIFITAHRDF--ALEGFNTGAVDYLVKPVRFERFLKAVTRAR 117

		           N  +L+  +     + P+++ ++A   F  A++    GA DYL KP      +  + RA 

		Sbjct: 61  NAFDLLPRIKKARPDLPVLV-MSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119

		

		Query: 118 NYITKKHLKEEEPKEKQDRI 137

		               ++  K E+  +    +

		Sbjct: 120 AEPKRRPSKLEDDSQDGMPL 139

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score =  143 bits (362), Expect = 3e-42

		 Identities = 59/236 (25%), Positives = 116/236 (49%), Gaps = 6/236 (2%)

		

		Query: 89  NINTVIFSFIPPFFVK-ILFDTIKLYRESLSFQKQKLDLEIQNINIEKEFLKAQLNPHFL 147

		              ++IF+ +   F+  +L+     ++     +  +  +       +   LKAQ+NPHF+

		Sbjct: 116 LALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFM 175

		

		Query: 148 FNTLNNLYGLVVKQDSRASEVVLNLSDIMAYTLYECGSEKVMLDKELEFIENYFNLEKLR 207

		           FN LNN+  L+++  ++A E++ +LS++M Y+L    + +V L  EL  +++Y  L  ++

		Sbjct: 176 FNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQ 235

		

		Query: 208 HPTDREITLEIYRKEDISGLYIAPLITFTFIENAFKYGLKSRKKS-FLKINIKIDNKKFL 266

		              DR +  E      I  + + P++  T +EN  K+G+    +   + +    DN    

		Sbjct: 236 FE-DR-LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVT 293

		

		Query: 267 FSLKNDKSGNNNDKKYTNIGGIGLENVKKRLQLLYPDSHLLEIEETYESFNVYLEI 322

		             ++N  S    + K +   G GL+NV++RLQ+LY     +++ E     N  + I

		Sbjct: 294 LEVENTGSLALKNTKEST--GTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347

		

		

		>ANTHRAXTOXNA#Anthrax toxin LF subunit signature.

		          Length = 800

		

		 Score = 30.1 bits (67), Expect = 0.037

		 Identities = 27/127 (21%), Positives = 50/127 (39%), Gaps = 21/127 (16%)

		

		Query: 668 KSESPNFLIEKPSFVFQTEHEISLPKGYKMSMNAFYTPQMVSGNALTGAIGSIDLGIQKK 727

		           K E+P  +I    +   +E           S   +Y      G  ++  I S D  +  +

		Sbjct: 146 KRETPKLIINIKDYAINSEQ----------SKEVYYE----IGKGISLDIISKDKSLDPE 191

		

		Query: 728 FLE--NKLVARVAISDIFYTNNFRAKSYFNNTIINLNHKEQS-----RVLSLSLNYSFSG 780

		           FL     L      SD+ ++  F+ K   NN  I++N  +++        SL+ +Y F+ 

		Sbjct: 192 FLNLIKSLSDDSDSSDLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAP 251

		

		Query: 781 GDKPKLQ 787

		             +  L+

		Sbjct: 252 DHRTVLE 258

		

		

		>OMADHESIN#Yersinia outer membrane adhesin signature.

		          Length = 455

		

		 Score = 34.9 bits (79), Expect = 6e-04

		 Identities = 34/108 (31%), Positives = 59/108 (54%), Gaps = 6/108 (5%)

		

		Query: 193 GIYARSWGYASIAMGSSAQASNDYRTAIGPNAEASGESSMALGTNAKASGGKSLAIGGFA 252

		           G+ A + G  SIA+G++A+A+     A+G  + A+G +S+A+G  +KA G  ++  G  +

		Sbjct: 62  GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121

		

		Query: 253 SGDYS-LAISGNSEDYPSVRSV-MNSIATGKYSIAISNAPGYSKSVAS 298

		           +     +AI   +    +  +V  NS A  K S+AI    G+S  VA+

		Sbjct: 122 TAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAI----GHSSHVAA 165

		

		

		

		 Score = 29.1 bits (64), Expect = 0.048

		 Identities = 29/86 (33%), Positives = 50/86 (58%), Gaps = 9/86 (10%)

		

		Query: 184 ALGYMSFAQGIYARSWGYAS------IAMGSSAQASNDYRTAIGPNAEASGESSMALG-- 235

		           A+G +S A G  A ++G AS      +A+G+ A  S D   A+G N++A  ++S+A+G  

		Sbjct: 102 AIGPLSKALGDSAVTYGAASTAQKDGVAIGARASTS-DTGVAVGFNSKADAKNSVAIGHS 160

		

		Query: 236 TNAKASGGKSLAIGGFASGDYSLAIS 261

		           ++  A+ G S+AIG  +  D   ++S

		Sbjct: 161 SHVAANHGYSIAIGDRSKTDRENSVS 186

		

		

		>cdtoxina#Cytolethal distending toxin A signature.

		          Length = 258

		

		 Score = 29.7 bits (66), Expect = 0.005

		 Identities = 11/27 (40%), Positives = 15/27 (55%)

		

		Query: 5  IILTGLLSLGLLTGCNSQKQNDMNEPK 31

		          I + G+L   LL GC+S K     +PK

		Sbjct: 8  IFIAGILIPILLNGCSSGKNKAYLDPK 34

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 80.6 bits (199), Expect = 3e-18

		 Identities = 24/136 (17%), Positives = 51/136 (37%), Gaps = 1/136 (0%)

		

		Query: 4   KILWIDDEVDLLKPHIVFLENKGYQVTPINNVNEALEILDEESFSLVLLDENMPGISGLD 63

		            IL  DD+  +       L   GY V   +N       +      LV+ D  MP  +  D

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 64  AIPLLKEKNSAMKIVMVTKSEEEHIMEQAIGSQIADYILKPVNPNQVLLSLKKNLQSDDL 123

		            +P +K+    + +++++         +A      DY+ KP +  +++  + + L     

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124

		

		Query: 124 VEQQTKQEYQQEFRNI 139

		                 ++  Q+   +

		Sbjct: 125 -RPSKLEDDSQDGMPL 139

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 39.7 bits (92), Expect = 4e-05

		 Identities = 35/249 (14%), Positives = 71/249 (28%), Gaps = 23/249 (9%)

		

		Query: 201  TELTASQNIKANLVRREEEKTIKKQDVE-AREAILELEKQLAEKEETQ-KREVENIKARE 258

		                + Q  K      ++      Q+ E A+EA   ++      E  Q   E +  +  E

		Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099

		

		Query: 259  NAEILKVAEEERLKYESVRIATEEALQIAEENKQRQVVIAAKNKERADLVETERVQKDKM 318

		              E   V +EE+ K E+ +      +      KQ Q              ET + Q +  

		Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ-------------SETVQPQAEP- 1145

		

		Query: 319  LEATERERIVALADIEKDKAVELEKKNIQDVIRE--RLAKEKTVVEEQQNIYDVEALKSA 376

		              A E +  V + + +       + +               ++      N        + 

		Sbjct: 1146 --ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203

		

		Query: 377  ERDKQVQLIIAAREAEERLIAETKAAEARKLAAEKDAQKYVIEAQAKRDAAEKEAEARKI 436

		                Q  +   +    +     +  +    +     +        A  D       A  +

		Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR-STVALCDLTSTNTNA--V 1260

		

		Query: 437  IADALAKEE 445

		            ++DA AK +

		Sbjct: 1261 LSDARAKAQ 1269

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 29.4 bits (66), Expect = 0.016

		 Identities = 9/57 (15%), Positives = 22/57 (38%), Gaps = 11/57 (19%)

		

		Query: 188 DIKSAAAGTILFAGEKSGYGKCVIISHGNGLATLYGHLSQVLVKANDKIKAGETIAK 244

		           +I + A G +  +G          I            + +++VK  + ++ G+ + K

		Sbjct: 81  EIVATANGKLTHSGRS------KEIKPIEN-----SIVKEIIVKEGESVRKGDVLLK 126

		

		

		>BINARYTOXINB#Binary toxin B family signature.

		          Length = 764

		

		 Score = 28.5 bits (63), Expect = 0.027

		 Identities = 12/38 (31%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

		

		Query: 163 ESGKTILIETDAVYGTNDAFYEAKGSYSFMHTCNTWAN 200

		           E  K + ++TD VYG N A Y  +     + T + W+ 

		Sbjct: 472 EKTKQLRLDTDQVYG-NIATYNFENGRVRVDTGSNWSE 508

		

		

		>cloacin#Cloacin signature.

		          Length = 551

		

		 Score = 35.1 bits (80), Expect = 6e-04

		 Identities = 19/39 (48%), Positives = 23/39 (58%)

		

		Query: 92  GDGSGSGGDSSGGSGNGDGSGGDSSGGSGSSYPNDSGYA 130

		           G GSGSG    GGSG+G+G G  +SGG   +  N S  A

		Sbjct: 47  GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85

		

		

		

		 Score = 31.2 bits (70), Expect = 0.011

		 Identities = 14/43 (32%), Positives = 19/43 (44%)

		

		Query: 92  GDGSGSGGDSSGGSGNGDGSGGDSSGGSGSSYPNDSGYAVMDT 134

		             G GSG  + GG+GN  G  G     S  + P   G+  + T

		Sbjct: 55  HWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALST 97

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 50.4 bits (120), Expect = 1e-08

		 Identities = 31/232 (13%), Positives = 60/232 (25%), Gaps = 22/232 (9%)

		

		Query: 202  LLEDFKKNEAALTAELKQKQAQAKKIEGEIRKIINEEIAAAKAKEEAERKARLERERLAR 261

		                        T    Q    +     E    ++E      A            E   +

		Sbjct: 987  KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046

		

		Query: 262  EAAAREKARIDAENKARAEALERERKKAEAEAARLAEIERKKQDDARKQAELAKAEENAR 321

		            E+   EK   DA      E   + R+ A+   + +            +  E+A++    +

		Sbjct: 1047 ESKTVEKNEQDAT-----ETTAQNREVAKEAKSNV--------KANTQTNEVAQSGSETK 1093

		

		Query: 322  NEARRIAAEKDAREAAARAKA-AEEKAKAARDAEAELAKRK--EEEKKKAEEKTKTAFGV 378

		                    E    E   +AK   E+  +  +       K++  E  + +AE   +     

		Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN---- 1149

		

		Query: 379  GAATGSNFAENRGRIGFPVERGQVTHRFGRQPHPVFKNIVEENNGIRIAVSP 430

		                  N  E + +     +  Q                   N G  +  +P

		Sbjct: 1150 --DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199

		

		

		

		 Score = 47.8 bits (113), Expect = 1e-07

		 Identities = 34/226 (15%), Positives = 68/226 (30%), Gaps = 22/226 (9%)

		

		Query: 162  AEIQQALKLKQKSVKEKENILTQQQKDLLVIQNDRKQRELLLEDFKKNEAAL-TAELKQK 220

		            +E  + +    K   +      Q   +        + RE+  E     +A   T E+ Q 

		Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETT-----AQNREVAKEAKSNVKANTQTNEVAQS 1088

		

		Query: 221  QAQAKKIEGEIRKIINEEIAAAKAKEEAERKARLERERLAREAAAREKARIDAENKARAE 280

		             ++ K+ +    K          A  E E KA++E E+        E  ++ ++   + E

		Sbjct: 1089 GSETKETQTTETKE--------TATVEKEEKAKVETEKTQ------EVPKVTSQVSPKQE 1134

		

		Query: 281  ALERERKKAEAEAARLA--EIERKKQDDARKQAELAKAEENARNEARRIAAEKDAREAAA 338

		              E  + +AE          I+  +            A+E + N  + +          +

		Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194

		

		Query: 339  RAKAAEEKAKAARDAEAELAKRKEEEKKKAEEKTKTAFGVGAATGS 384

		              +  E    A            + + +           V  AT S

		Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTS 1240

		

		

		

		 Score = 42.7 bits (100), Expect = 3e-06

		 Identities = 24/150 (16%), Positives = 42/150 (28%), Gaps = 6/150 (4%)

		

		Query: 226  KIEGEIRKIINEEIAAAKAKEEAERKARLERERLAREAAAREKARIDAENKARAEALERE 285

		            ++E   + +    I      +          E +AR   A       A      E +   

		Sbjct: 984  EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043

		

		Query: 286  RKKAEAEAARLAEIERKKQDDARKQAELAKAEENARNEARRIAAEKDAREAAARAKAAEE 345

		             K+         E   +   +   Q      E  +  +A     E  A+  +   +    

		Sbjct: 1044 SKQESKTV----EKNEQDATETTAQNREVAKEAKSNVKANTQTNEV-AQSGSETKETQTT 1098

		

		Query: 346  KAKAARDAEAELAKRKEEEKKKAEEKTKTA 375

		            + K     E E  K K E +K  E    T+

		Sbjct: 1099 ETKETATVEKE-EKAKVETEKTQEVPKVTS 1127

		

		

		

		 Score = 34.7 bits (79), Expect = 0.001

		 Identities = 24/127 (18%), Positives = 46/127 (36%), Gaps = 6/127 (4%)

		

		Query: 253  RLERERLAREAAAREKARIDAENKARAEALERERKKAEAEAARLAEIERKKQDDARKQAE 312

		             L    + +     +   I   N  +A+         E      A +         +  E

		Sbjct: 979  DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038

		

		Query: 313  LAKAEENARNEARRIA-AEKDAREAAARAKAAEEKAKAARDAE---AELAKRKEEEKKKA 368

		                 EN++ E++ +   E+DA E  A+ +   ++AK+   A     E+A+   E K+  

		Sbjct: 1039 T--VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096

		

		Query: 369  EEKTKTA 375

		              +TK  

		Sbjct: 1097 TTETKET 1103

		

		

		>PF01540#Adhesin lipoprotein

		          Length = 475

		

		 Score = 28.5 bits (63), Expect = 0.040

		 Identities = 23/108 (21%), Positives = 48/108 (44%), Gaps = 12/108 (11%)

		

		Query: 209 KEYWLEVWKDAKGKVDEKQQLRNAATYYNGHKNNPNFIARLSKEAMKTTFQSSATNSYHE 268

		           K+ W +   + K + D+K    N        KN    + +++ EA + +   + T +  E

		Sbjct: 341 KKAWSKELAEIKAEDDKKLAEENQKI-----KNGVEELKKINNEAFELSKTVNKTIAELE 395

		

		Query: 269 YGFKVD-------INYINYLLNEAWYNDRLESMQNYPNDFSVEYLETF 309

		             FK+D        N+ + LL+++   D   ++ +    F++  LE+F

		Sbjct: 396 KKFKIDVSFKEQLKNFADDLLDKSRQIDEFTTVTSTQEGFTLAELESF 443

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 35.5 bits (82), Expect = 1e-04

		 Identities = 43/226 (19%), Positives = 78/226 (34%), Gaps = 45/226 (19%)

		

		Query: 7   LIASLFKEVDLDDVVFFA--SGVSNSLATDKAQFQREE----NLLRKNIKETPNRLFLYF 60

		            +  LF     + V        V  SL    A          N+L          L LY 

		Sbjct: 66  GMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL-LYA 124

		

		Query: 61  STCSIYDSSKA------------ESPYVLHKLKMEQVVAETCSR-YLV----LRLSNVVG 103

		           S+ S+Y  ++              S Y   K   E ++A T S  Y +    LR   V G

		Sbjct: 125 SSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE-LMAHTYSHLYGLPATGLRFFTVYG 183

		

		Query: 104 KGGNPNLLMNYLVNSVKRGEVINV--HTKATRNLIDAED-VKAVVFNLLKQKQLN----- 155

		             G P++ +     ++  G+ I+V  + K  R+    +D  +A++         +     

		Sbjct: 184 PWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQWTV 243

		

		Query: 156 ------------RVVNLAYIDNYTIIEILEILESAIKLKPNLNLIK 189

		                       RV N+       +++ ++ LE A+ ++   N++ 

		Sbjct: 244 ETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP 289

		

		

		>PF05704#Capsular polysaccharide synthesis protein

		          Length = 307

		

		 Score = 49.1 bits (117), Expect = 4e-09

		 Identities = 22/100 (22%), Positives = 48/100 (48%), Gaps = 5/100 (5%)

		

		Query: 1   MIPKKIHYFWF-GKNPKPSITEYCIQSWRKYLPDYEIIEWNEDNFD--ITQNNFVKTAYE 57

		           M  K I   W  G    P I + C+ S +K   D+++I  + +N+   +   +F+   ++

		Sbjct: 66  MRQKYIFICWLQGIEKAPYIVQQCVASVKKNSGDFKVIIIDGNNYKEWVDIPDFLIKRWQ 125

		

		Query: 58  N--RKWAFVSDFARAQILYEHGGFYLDTDMEVKNSFNDFL 95

		                 A+ SD  R  +L ++GG ++D  + + +   +++

		Sbjct: 126 EGKMLDAWFSDILRLFLLCKYGGLWIDATVYMFDKVPNYI 165

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score =  545 bits (1407), Expect = 0.0

		 Identities = 166/684 (24%), Positives = 288/684 (42%), Gaps = 73/684 (10%)

		

		Query: 8   TRNIGIAAHIDAGKTTTTERILFYTGKTHKIGEVHDGASTMDWMEQEAERGITITSAATT 67

		             NIG+ AH+DAGKTT TE +L+ +G   ++G V  G +  D    E +RGITI +  T+

		Sbjct: 3   IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62

		

		Query: 68  CNWVFPRHEGKPTADAKDYHFNIIDTPGHVDFTVEVNRSLRVLDGLVFLFSAVDGVEPQS 127

		             W             ++   NIIDTPGH+DF  EV RSL VLDG + L SA DGV+ Q+

		Sbjct: 63  FQW-------------ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQT 109

		

		Query: 128 ETNWRLADNYKVARMGFVNKMDRQGADFLNVVNQVKEMLGSNAVPIVLPIGAEEDFKGVV 187

		              +       +  + F+NK+D+ G D   V   +KE L +  V            K  V

		Sbjct: 110 RILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVI-----------KQKV 158

		

		Query: 188 DLIKNRAIIWHEETQGATFDVVPIPDDMKDDVLAYRQNLVEAVAEYDESLLEKFFEDPDS 247

		           +L  N  +                  +  +          + V E ++ LLEK+     S

		Sbjct: 159 ELYPNMCVT-----------------NFTESEQ------WDTVIEGNDDLLEKYMSGK-S 194

		

		Query: 248 ITEEEINDALRKATIDLSIIPMTCGSSFKNKGVQFMLDAVCRYLPSPLDKDDINGTDPNT 307

		           +   E+         + S+ P+  GS+  N G+  +++ +     S              

		Sbjct: 195 LEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------- 243

		

		Query: 308 DAEISRKPDVNEPFSALAFKIATDPFVGRLAFFRAYSGRLDAGSYVLNTRSGNKERISRI 367

		                             FKI       RLA+ R YSG L     V  +    K +I+ +

		Sbjct: 244 --------RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKE-KIKITEM 294

		

		Query: 368 YQMHANKQNPVEYIEAGDIGAAVGFKDIKTGDTLSDEKNPIVLESMIFPDPVIGIAVEPK 427

		           Y     +   ++   +G+I      + +K    L D K     E +  P P++   VEP 

		Sbjct: 295 YTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTTVEPS 353

		

		Query: 428 TKADQDKLGNALAKLAEEDPTFQVKTDEASGQTIISGMGELHLDIIVDRLKREFKVEVNQ 487

		               ++ L +AL ++++ DP  +   D A+ + I+S +G++ +++    L+ ++ VE+  

		Sbjct: 354 KPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEI 413

		

		Query: 488 GQPQVEYKEALTATANHREVYKKQSGGRGKFADIVFEIGPADEGKTGLEFINEIKGGNIP 547

		            +P V Y E     A +      +      +A I   + P   G +G+++ + +  G + 

		Sbjct: 414 KEPTVIYMERPLKKAEY--TIHIEVPPNPFWASIGLSVSPLPLG-SGMQYESSVSLGYLN 470

		

		Query: 548 KEFIPSVEKGFKEAMKNGPLAGFEVEAMKITLKDGSFHAVDSDQLSFELAAKLGFKAAGK 607

		           + F  +V +G +   + G L G+ V   KI  K G +++  S    F + A +  +   K

		Sbjct: 471 QSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLK 529

		

		Query: 608 AAKAVIMEPIMKLEVVTPEEYMGDIVGDLNRRRGTINGMDDRNNAKVIKAFVPLSEMFGY 667

		            A   ++EP +  ++  P+EY+     D  +    I     +NN  ++   +P   +  Y

		Sbjct: 530 KAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEY 589

		

		Query: 668 VTSLRTLSSGRATSSMEFEKYEPA 691

		            + L   ++GR+    E + Y   

		Sbjct: 590 RSDLTFFTNGRSVCLTELKGYHVT 613

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 28.0 bits (62), Expect = 0.005

		 Identities = 9/33 (27%), Positives = 20/33 (60%)

		

		Query: 37  LIISFVNIFPKFEGRGLGKALIKEAISFAREHQ 69

		            +I  + +   +  +G+G AL+ +AI +A+E+ 

		Sbjct: 90  ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 38.2 bits (88), Expect = 6e-06

		 Identities = 31/141 (21%), Positives = 57/141 (40%), Gaps = 24/141 (17%)

		

		Query: 29  SHQYIKSNKNLATELSKKYEIPASVIMAIAFVETGGGSCK----NSKQLNNHFGIVGKNH 84

		           S  ++      A   S++  +P  +I+A A +E+G G  +    N +   N FG+    +

		Sbjct: 149 SKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGN 208

		

		Query: 85  QKA-------------------TKYKQFSSKEESFDAFCKMLTRKKYYAELKGNNDFALW 125

		            K                     K++ +SS  E+   +  +LTR   YA +         

		Sbjct: 209 WKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQG 268

		

		Query: 126 IKTIANNGYSTQPKEWIRRLT 146

		            + + + GY+T P  + R+LT

		Sbjct: 269 AQALQDAGYATDP-HYARKLT 288

		

		

		>V8PROTEASE#V8 serine protease family signature.

		          Length = 336

		

		 Score = 48.8 bits (116), Expect = 4e-08

		 Identities = 16/55 (29%), Positives = 26/55 (47%), Gaps = 1/55 (1%)

		

		Query: 629 YMPVNFLS-DNDITGGNSGSPVIDANGHLIGIAFDGNSEALSGDIVFEPKLQKTI 682

		           Y+    +  D   TGGNSGSPV +    +IGI + G     +G +     ++  +

		Sbjct: 220 YLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNEFNGAVFINENVRNFL 274

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 38.9 bits (90), Expect = 2e-04

		 Identities = 23/76 (30%), Positives = 41/76 (53%), Gaps = 4/76 (5%)

		

		Query: 888 IESPKKTTVVKDFTFEVSNISLYYGKTIVSRQWEFPGAAQVNNAETDKPSVVYNKYGKFG 947

		           I+S     V ++  F+ +      G+ I + +W+F G  + +N    K +  YNK G++ 

		Sbjct: 779 IKSDSSVIVEEEINFDGTESKDEDGE-IKAYEWDF-GDGEKSNEA--KATHKYNKTGEYE 834

		

		Query: 948 VKLTLTDSEGQNYTQT 963

		           VKLT+TD+ G   T++

		Sbjct: 835 VKLTVTDNNGGINTES 850

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 31.2 bits (70), Expect = 0.024

		 Identities = 27/112 (24%), Positives = 43/112 (38%), Gaps = 20/112 (17%)

		

		Query: 854 LYRNKFKPIAQPLATNISKAQLANANMT----------VQFESYSIVNQDN--VQWEWSF 901

		           +Y   F  +     T++   +   A +           + F+     ++D     +EW F

		Sbjct: 753 VYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGTESKDEDGEIKAYEWDF 812

		

		Query: 902 NPKPYSIDNPKARNPKVVFKYN--GEYDVTLKVTTPQGTDSKTIKKMIVVNN 951

		                  D  K+   K   KYN  GEY+V L VT   G  +   KK+ VV +

		Sbjct: 813 G------DGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIKVVED 858

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 80.1 bits (197), Expect = 7e-20

		 Identities = 49/188 (26%), Positives = 87/188 (46%), Gaps = 3/188 (1%)

		

		Query: 7   KNVLITGGASGIGKIMARLSLEKGARVIIWDIDHAKIDETILQFSSLG-SIFGYKVDVSN 65

		           K   ITG A GIG+ +AR    +GA +   D +  K+++ +    +       +  DV +

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 66  YDEVQHFATKTKQKIGNIDILINNAGIVVGKYFHEHSQKDILKTIEINTNAPMVITNLFL 125

		              +     + ++++G IDIL+N AG++     H  S ++   T  +N+      +    

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 126 QDMLTQNSGHICNIASSAGLVSNPKMSVYAGSKWAVVGWSDSLRLEMELLKKNIKVTTIM 185

		           + M+ + SG I  + S+   V    M+ YA SK A V ++    L +EL + NI+   + 

		Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKC--LGLELAEYNIRCNIVS 186

		

		Query: 186 PYYINTGM 193

		           P    T M

		Sbjct: 187 PGSTETDM 194

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score = 79.6 bits (196), Expect = 2e-18

		 Identities = 38/124 (30%), Positives = 67/124 (54%), Gaps = 7/124 (5%)

		

		Query: 341 PKPQEAYAVEA-TGALKG-IFFNFNKASIRSESNTKLDQAAEVIKSSN--GGTFLVVGHT 396

		           P P  A  V+     LK  + FNFNKA+++ E    LDQ    + + +   G+ +V+G+T

		Sbjct: 202 PAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYT 261

		

		Query: 397 DVKGNANYNLKLSRERAASVVAALEARGVNPSQLKSKGVGSAEATVPASASNEERMKDRK 456

		           D  G+  YN  LS  RA SVV  L ++G+   ++ ++G+G +    P + +  + +K R 

		Sbjct: 262 DRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESN---PVTGNTCDNVKQRA 318

		

		Query: 457 VVVE 460

		            +++

		Sbjct: 319 ALID 322

		

		

		>V8PROTEASE#V8 serine protease family signature.

		          Length = 336

		

		 Score = 68.9 bits (168), Expect = 7e-15

		 Identities = 32/167 (19%), Positives = 57/167 (34%), Gaps = 32/167 (19%)

		

		Query: 120 PTGLGSGVIISPDGYIISNNHVVAGASKLEVTLS------------NKKTYVAKLIGSDP 167

		            T + SGV++  D  +++N HVV         L             N      ++     

		Sbjct: 100 GTFIASGVVVGKD-TLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158

		

		Query: 168 STDIALLKIED--------SGLPYLNFANSDLLEVGQWVVAVGNPLGLNSTVTAGIVSAK 219

		             D+A++K             +     +N+   +V Q +   G P        A +  +K

		Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPV---ATMWESK 215

		

		Query: 220 GRSIDLLRQQSKTPIESFIQTDAVINRGNSGGALVNLNGDLVGINSA 266

		           G+   L            +Q D     GNSG  + N   +++GI+  

		Sbjct: 216 GKITYL--------KGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG 254

		

		

		>PF03544#Gram-negative bacterial tonB protein

		          Length = 243

		

		 Score = 40.7 bits (95), Expect = 2e-06

		 Identities = 38/190 (20%), Positives = 62/190 (32%), Gaps = 11/190 (5%)

		

		Query: 86  ILEQPKEETPPPPPPPKVEEEKIEIIQNVVPEPVKAPKVETPPPPISKQLETTTGLVNQE 145

		           ++     E P    PP     + E     +PEP K   V    P    +       V + 

		Sbjct: 54  MVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK--PKPKPVKKV 111

		

		Query: 146 GVKKPSYAPPPPPPSTGKGTTVEVKPQVSTTEVYTTVDQEAEFSGGGINGFRSAFQESFD 205

		              K    P    P++    T   +P  ST        +       G         +   

		Sbjct: 112 EQPKRDVKPVESRPASPFENTAPARPTSSTAT--AATSKPVTSVASGPRALSRNQPQYPA 169

		

		Query: 206 TSVMEGDEGTLKAEVTFVVERDGSLSQVKVTGS--NSTFNREAERAVKSIKKKWTPGKVN 263

		            +     EG +K  V F V  DG +  V++  +   + F RE + A++    ++ PGK  

		Sbjct: 170 RAQALRIEGQVK--VKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRR--WRYEPGKPG 225

		

		Query: 264 GE-PVRSRFR 272

		               V   F+

		Sbjct: 226 SGIVVNILFK 235

		

		

		>SUBTILISIN#Subtilisin serine protease family (S8) signature.

		          Length = 326

		

		 Score = 81.0 bits (200), Expect = 2e-18

		 Identities = 62/325 (19%), Positives = 98/325 (30%), Gaps = 77/325 (23%)

		

		Query: 119 GQGMTAYVWDAGSVRPSHREFGNRVTVGDGASHNGDN----------HATHVGGTIAATG 168

		           G+G+   V D G     H +   R+  G   + + +           H THV GTIAAT 

		Sbjct: 40  GRGVKVAVLDTG-CDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATE 98

		

		Query: 169 VTAAAKGMASKALIRSYD--WSSDYSEASTAARAGMLLSNHSYGYNSLSLPDWYFGAYIG 226

		                 G+A +A +            +     +             S+SL         G

		Sbjct: 99  NENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSL---------G 149

		

		Query: 227 ESADWDRLMYSAPY-----YLMCVAAGNDGSNYGYNQRTGKYELLNASPLGGATNDYDKL 281

		              D   L  +         L+  AAGN+G                         D    

		Sbjct: 150 GPEDVPELHEAVKKAVASQILVMCAAGNEGDG-------------------DDRTDELGY 190

		

		Query: 282 TGHSTSKNALVVANANDANVDAQGNLLSVTIASSSSQGPTDDLRVKPDIAGNGVQVYSPV 341

		            G       + V   N               +  S+         + D+   G  + S  

		Sbjct: 191 PG--CYNEVISVGAINFDR----------HASEFSNSNN------EVDLVAPGEDILS-- 230

		

		Query: 342 AYTSTSTGKTYGNAYYDSYTGTSMASPNVTGSLLLVQQHYNNKEGQFMLGAQLKGLALHT 401

		                    T     Y +++GTSMA+P+V G+L L++Q  N    + +   +L    +  

		Sbjct: 231 ---------TVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKR 281

		

		Query: 402 ADDAGMEGPDANFGWGLLNVKKMVE 426

		               G        G GLL +  + E

		Sbjct: 282 TIPLG--NSPKMEGNGLLYLTAVEE 304

		

		

		>adhesinb#Adhesin B signature.

		          Length = 310

		

		 Score = 31.7 bits (72), Expect = 0.003

		 Identities = 7/47 (14%), Positives = 25/47 (53%), Gaps = 3/47 (6%)

		

		Query: 208 EAKGKWELNPKQ---IEALKENLDYIKKRNIPYILVQAPITKKLYES 251

		            +   WE+N ++    + +K  ++ ++K  +P + V++ +  +  ++

		Sbjct: 219 PSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKT 265

		

		

		>DNABINDINGHU#Prokaryotic integration host factor signature.

		          Length = 91

		

		 Score = 33.5 bits (77), Expect = 4e-05

		 Identities = 14/49 (28%), Positives = 24/49 (48%)

		

		Query: 31 NQKSLAKEISGRSSLTAGDVNNVIQNLLDILPSKLVEGNSVQLGDFGTF 79

		          N++ L  +++  + LT  D    +  +   + S L +G  VQL  FG F

		Sbjct: 3  NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNF 51

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 28.3 bits (63), Expect = 0.039

		 Identities = 19/72 (26%), Positives = 31/72 (43%), Gaps = 6/72 (8%)

		

		Query: 113 VLGKIVTNGKTLEELKIELT---QKLKRYVINPTVAIKYSNYKVTILGEVNRPGQ---YI 166

		           +L K+      +  L +EL    ++ +  VI   V++K    KV   G V    +    I

		Sbjct: 300 ILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVI 359

		

		Query: 167 IPDGKTRIVDAL 178

		           +P+  T  V AL

		Sbjct: 360 VPEDDTLEVTAL 371

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  250 bits (640), Expect = 9e-84

		 Identities = 93/337 (27%), Positives = 153/337 (45%), Gaps = 32/337 (9%)

		

		Query: 5   KILITGGAGFIGSNLTEHFLSKNYQVRVLDNFSTGHKYNIEP----FFKNEKFELIEGDI 60

		           K L+TG AGFIG ++++  L   +QV  +DN +  +  +++           F+  + D+

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61

		

		Query: 61  RNLEICNE--ACEGVDYVLHQAALGSVPRSIENPITSNEVNVSGFLNMLVAARDAKVKRF 118

		            + E   +  A    + V       +V  S+ENP    + N++GFLN+L   R  K++  

		Sbjct: 62  ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121

		

		Query: 119 VYAASSSTYGDSQSLP-KVEEVIGKPLSPYAITKYVNELYADVFSRTYGMECIGLRYFNV 177

		           +YA+SSS YG ++ +P   ++ +  P+S YA TK  NEL A  +S  YG+   GLR+F V

		Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181

		

		Query: 178 FGRRQDPKGAYAAVIPKFVIQLMNYQSPTINGDGSYSRDFTYIDNVIQMNELAM---LTD 234

		           +G    P  A      KF   ++  +S  +   G   RDFTYID++ +            

		Sbjct: 182 YGPWGRPDMAL----FKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237

		

		Query: 235 NPE------------AVNTVYNTAVGDRTTIKQMAQLLKEYLSKYDEKIGEVEILHGPNR 282

		           + +            A   VYN        +    Q L++ L        E +    P +

		Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI------EAKKNMLPLQ 291

		

		Query: 283 VGDIPHSLASIDKAKENLGYMPSHIFKEGLKEAVDWY 319

		            GD+  + A      E +G+ P    K+G+K  V+WY

		Sbjct: 292 PGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 32.4 bits (73), Expect = 0.014

		 Identities = 20/65 (30%), Positives = 35/65 (53%), Gaps = 2/65 (3%)

		

		Query: 33  GAHYWCLSPFKEEKTPSCQIKANTQRYIDYSSGISG-DAVSLLMEVKRMTYPEAIEELAK 91

		           G  Y C S     K  SC++   T ++ D+S+G SG D + L  E+  +   +A  ++A+

		Sbjct: 37  GHEYECGS-LAGGKGDSCKVNVTTGKWCDFSTGESGRDLLDLYAEIHGLKVSKAAAQVAR 95

		

		Query: 92  MQGLQ 96

		            +GL+

		Sbjct: 96  EEGLE 100

		

		

		>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein

		           signature.

		          Length = 533

		

		 Score = 28.4 bits (63), Expect = 0.038

		 Identities = 17/57 (29%), Positives = 33/57 (57%), Gaps = 3/57 (5%)

		

		Query: 215 IEKEIKEMTAEELAKAKNNLKANISKKKKALKETDDEERKSKLSE-DLAMLEKKQKL 270

		           I K ++++ A++   AKN  K +  +++ A +    +E K K +E DL+M+  + KL

		Sbjct: 390 IRKAMEKLAAQQEEDAKNQGKGDCKQQQGASE--KSKEGKVKETEFDLSMVVGQVKL 444

		

		

		>PF07675#Cleaved Adhesin

		          Length = 1358

		

		 Score = 29.7 bits (66), Expect = 0.011

		 Identities = 10/16 (62%), Positives = 10/16 (62%)

		

		Query: 83  PTPNPEPNPNPRPNEG 98

		           P   P PNPNP PN G

		Sbjct: 614 PNGTPNPNPNPNPNPG 629

		

		

		>OMADHESIN#Yersinia outer membrane adhesin signature.

		          Length = 455

		

		 Score = 32.2 bits (72), Expect = 0.002

		 Identities = 16/42 (38%), Positives = 20/42 (47%)

		

		Query: 57  HANSPLGVQLDSLADMISFGLIPGLAMYKLLEPYGVNIGNFT 98

		           H    L  +LD L   +  GL    A+  L +PYGV   NFT

		Sbjct: 366 HKFRQLDNRLDKLDTRVDKGLASSAALNSLFQPYGVGKVNFT 407

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 34.4 bits (79), Expect = 0.004

		 Identities = 23/130 (17%), Positives = 51/130 (39%), Gaps = 20/130 (15%)

		

		Query: 222 KTDLPVNKKNVLVLKGEKGVGKSAILKDLYEKLDKENYTVLGIKADKFYCKSISE--LES 279

		           +TDL +      ++ GE G GK  + + L++   + N   +          +I    +ES

		Sbjct: 158 QTDLTL------MITGESGTGKELVARALHDYGKRRNGPFV-----AINMAAIPRDLIES 206

		

		Query: 280 KLFDNQIT-F---DKVIKSLQEKEDKIVVLIDQIDAMSLSLSSS--REFIETYIRLISSL 333

		           +LF ++   F           E+ +   + +D+I  M +   +   R   +     +   

		Sbjct: 207 ELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGR 266

		

		Query: 334 QDNK-NIRII 342

		              + ++RI+

		Sbjct: 267 TPIRSDVRIV 276

		

		

		>DNABINDINGHU#Prokaryotic integration host factor signature.

		          Length = 91

		

		 Score = 25.8 bits (57), Expect = 0.025

		 Identities = 18/73 (24%), Positives = 32/73 (43%), Gaps = 6/73 (8%)

		

		Query: 48  VSGADICAVLYALVDVMQTSLAEGQVVRLGEMGSMRVSISSEGKAKE----EEVTPAAIR 103

		           ++  D  A + A+   + + LA+G+ V+L   G+  V   +  K +     EE+   A +

		Sbjct: 17  LTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGRNPQTGEEIKIKASK 76

		

		Query: 104 NAKVVFTPGSDLK 116

		                F  G  LK

		Sbjct: 77  --VPAFKAGKALK 87

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  156 bits (395), Expect = 1e-44

		 Identities = 79/387 (20%), Positives = 137/387 (35%), Gaps = 77/387 (19%)

		

		Query: 2   SKIIGIDLGTTNSCVAVMEGKDPVVIPNAEGKRT-----TPSIVAFTEDGERKVGDPAKR 56

		           S  + IDLGT N+ + V      +  P+    R        S+ A        VG  AK+

		Sbjct: 10  SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAA--------VGHDAKQ 61

		

		Query: 57  QAVTNPKNTVYSIKRFIGANFKTDANEVSRVPYQVVEGSNDTVKVKIGDREYTPQEISAM 116

		                P N                           +    D V   I D  +  +++   

		Sbjct: 62  MLGRTPGNIA------------------------AIRPMKDGV---IAD-FFVTEKMLQH 93

		

		Query: 117 ILQKMKKTAEDYLGQEVSRAVITVPAYFNDAQRQATKEAGEIAGLKVERIINEPTAAALA 176

		            ++++     +   +   R ++ VP      +R+A +E+ + AG +   +I EP AAA+ 

		Sbjct: 94  FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150

		

		Query: 177 YGLDKVGKKDMNVVVFDCGGGTHDVSVLEMYEVDGNASFEVKATDGDTHLGGDDFDNVII 236

		            GL     +    +V D GGGT +V+V+ +  V                +GGD FD  II

		Sbjct: 151 AGLPV--SEATGSMVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAII 199

		

		Query: 237 DWMAAEFQAEEGVDLKSDAIALQRLKEAAEKAKVELSSSTQ----TEINLPYITATASGP 292

		           +++   + +  G             +  AE+ K E+ S+       EI +         P

		Sbjct: 200 NYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVP 246

		

		Query: 293 KHLVKTLTRAKFEQLAGDLIQRTIEPCKSAL-KNAGMSVSDIDE--IILVGGSTRIPAIQ 349

		           +      +    E L  + +   +     AL +      SDI E  ++L GG   +  + 

		Sbjct: 247 RGFTLN-SNEILEALQ-EPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLD 304

		

		Query: 350 EAVEKFFGKAPSKGVNPDEVVAIGAAI 376

		             + +  G       +P   VA G   

		Sbjct: 305 RLLMEETGIPVVVAEDPLTCVARGGGK 331

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 31.6 bits (71), Expect = 0.019

		 Identities = 59/389 (15%), Positives = 123/389 (31%), Gaps = 17/389 (4%)

		

		Query: 616 PDDKLKEAKKDLEDSQKAHSDAYNKLLEMDSDYYLERQKLAEKSLEAELAILDAE-RSKE 674

		            ++ LK    DL  + KA  D  ++L E  S+   + +K  +   E    I + E R  +

		Sbjct: 65  ENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKAD 124

		

		Query: 675 LNSQRKYQDDILKTIEDLEEKKKNAKSPEAAKNYEKALEKERSLLALHDKIVETSEEAHG 734

		           L    +   +         +  +  K+  AA+  +     E ++        +       

		Sbjct: 125 LEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAE 184

		

		Query: 735 HKVSEIKEKWITKRLSDFFESERLRIDKERASDDEAIQKISTMEEAKLALSKMTHLKLTQ 794

		               E ++  + K L            K +  + E     +   + + AL    +     

		Sbjct: 185 KAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTAD 244

		

		Query: 795 QELLQIKTLEDAKKALREDADRKMLESQLASLELQKEALEESLKGLTGEAAEKLKKDLDE 854

		              ++    E A       A+ +       +      A  ++L+        +      +

		Sbjct: 245 SAKIKTLEAEKAAL-EARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ 303

		

		Query: 855 LNIRITQVKGAIQGNKENDEHRASQERRQQLSQVDLLGFSADQWSEMFDNLNTTEGKIKA 914

		             +     +   +    + E +   E   Q  +      S      +  +L+ +    K 

		Sbjct: 304 SQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN-KISEASRQSLRRDLDASREAKKQ 362

		

		Query: 915 VTMATQALGNAFNRFAQLQQNLNEREMQRFTKNQDKKRKAL------LVQLNQGLISQEE 968

		           +    Q L          Q  ++E   Q   ++ D  R+A       L + N  L + E+

		Sbjct: 363 LEAEHQKLEE--------QNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEK 414

		

		Query: 969 YHKGIEALDTETAKKKSEIAHKQAVAEKA 997

		            +K +E     T K+K+E+  K     KA

		Sbjct: 415 LNKELEESKKLTEKEKAELQAKLEAEAKA 443

		

		

		

		 Score = 31.6 bits (71), Expect = 0.022

		 Identities = 42/244 (17%), Positives = 79/244 (32%), Gaps = 10/244 (4%)

		

		Query: 610 KSSSNKPDDKLKEAKKDLEDSQKAHSDAYNKLLEMDSDYYLERQKLAEKSLEAELAILDA 669

		                + +DK    K       +A      K LE   ++        +  LEAE A L A

		Sbjct: 97  AKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKT-LEAEKAALAA 155

		

		Query: 670 ERSKELNSQRKYQDDILKTIEDLEE--KKKNAKSPEAAKNYEKALEKERSLLALHDKIVE 727

		            ++    +     +        ++    +K A     A+  +          A   KI  

		Sbjct: 156 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKT 215

		

		Query: 728 TSEEAHGHKVSEIKEKWITKRLSDFFESERLRIDKERASDDEAIQKISTMEEAKLALSKM 787

		              E       +   +   +   +F  ++  +I    A       + + +E+A       

		Sbjct: 216 LEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN- 274

		

		Query: 788 THLKLTQQELLQIKTLEDAKKALREDADRKMLESQL--ASLELQKEALEESLKGLTGEAA 845

		                +  +  +IKTLE  K AL  +      +SQ+  A+ +  +  L+ S +      A

		Sbjct: 275 ----FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEA 330

		

		Query: 846 EKLK 849

		           E  K

		Sbjct: 331 EHQK 334

		

		

		

		 Score = 30.8 bits (69), Expect = 0.035

		 Identities = 53/341 (15%), Positives = 104/341 (30%), Gaps = 36/341 (10%)

		

		Query: 538 DLKRALDGLNDAIKNKNQAYSELNKEIAFKQKQVERLGLKDVKLDDSPVIEQNTTTYGAT 597

		           + K  L   + ++  K     EL    A  +K +E                +      A 

		Sbjct: 96  NAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAA 155

		

		Query: 598 RDANLAAKSTPTKSSSNKPDDKLKEAKKDLEDSQKAHSDAYNKLLEMDSDYYLERQKLAE 657

		           R A+L        + S     K+K  + +    +   ++    L    +    +  K   

		Sbjct: 156 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK--I 213

		

		Query: 658 KSLEAELAILDAERSKELNSQRKYQDDILKTIEDLEEKKKNAKSPEAAKNYEKALEKERS 717

		           K+LEAE A L A ++    +     +        ++  +    + E      +  +    

		Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALE--ARQAELEKALEG 271

		

		Query: 718 LLALHDKIVETSEEAHGHKVSEIKEKWITKRLSDFFESERLRIDKERASDDEAIQKIS-- 775

		            +          +     K +   EK   +  S    + R  + ++  +  EA +++   

		Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331

		

		Query: 776 --TMEEAKLALSK------------MTHLKLTQQELLQIKTLEDAKKALREDADRKM--- 818

		              +EE                       K  + E  +++      +A R+   R +   

		Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391

		

		Query: 819 -------------LESQLASLELQKEALEESLKGLTGEAAE 846

		                          S+LA+LE   + LEES K    E AE

		Sbjct: 392 REAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAE 432

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 33.1 bits (75), Expect = 7e-04

		 Identities = 19/163 (11%), Positives = 45/163 (27%)

		

		Query: 24  KQLQEITKVKTQNDSVFNSTNSKLFEVLNENKSLKAENISFKNEIEGYQSKIKELQEKSL 83

		           K L+      T + +   +  ++   +      L+       N      +KIK L+ +  

		Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKA 186

		

		Query: 84  SESSEDLVIENAKGVVKLTDKNGNSYEIGADNGTRILRTTATKLQNELSKKTNEVNNLKT 143

		           +  +    +E A           ++     +     L      L+  L    N       

		Sbjct: 187 ALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSA 246

		

		Query: 144 LTEKQKQTIEQLEEKNKNILKRTKTFRKEIKSIEDLLTKLQES 186

		             +  +     LE +   + K  +       +    +  L+  

		Sbjct: 247 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 289

		

		

		

		 Score = 28.9 bits (64), Expect = 0.017

		 Identities = 24/160 (15%), Positives = 51/160 (31%), Gaps = 4/160 (2%)

		

		Query: 37  DSVFNSTNSKLFEVLNENKSLKAENISFKNEIEGYQSKIKELQE--KSLSESSEDLVIEN 94

		                S    L +V       + EN + K +        K L++    L+E   +   + 

		Sbjct: 42  AVATRSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKL 101

		

		Query: 95  AKGVVKLTDKNGNSYEIGADNGTRILRTTATKLQNELSKKTNEVNNLKTLTEKQKQTIEQ 154

		            K    L++K     E+  +     L        N  +  + ++  L+            

		Sbjct: 102 RKNDKSLSEKASKIQEL--EARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 159

		

		Query: 155 LEEKNKNILKRTKTFRKEIKSIEDLLTKLQESSKTARKTI 194

		           LE+  +  +  +     +IK++E     L+       K +

		Sbjct: 160 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL 199

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 29.4 bits (66), Expect = 0.007

		 Identities = 11/77 (14%), Positives = 26/77 (33%), Gaps = 3/77 (3%)

		

		Query: 18  LIENKEDLTSIKNDLEAREANVTARENAIAERENKVSTRENDL--EAREANVTARENAIA 75

		           ++E +       N+L   ++ +   E+ I   + +          E  +      +N I 

		Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN-IG 312

		

		Query: 76  ERENEVSTRENDLEARE 92

		               E++  E   +A  

		Sbjct: 313 LLTLELAKNEERQQASV 329

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 81.0 bits (200), Expect = 2e-19

		 Identities = 68/339 (20%), Positives = 117/339 (34%), Gaps = 63/339 (18%)

		

		Query: 7   KILITGALGQIGTELTTKLVEIYGKENVIASGID------------KWREGITTAG-HYE 53

		           K L+TGA G IG  ++ +L+E      V+  GID               E +   G  + 

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLE--AGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQFH 57

		

		Query: 54  RIDVTNFKLLEDFIKENKITTVYHLASLLSGT--SEKQPLFAWKLNLEPLLHLCELAKEG 111

		           +ID+ + + + D         V+           S + P      NL   L++ E  +  

		Sbjct: 58  KIDLADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHN 116

		

		Query: 112 YLKKIFWPSSIAVFGKGIPKHNVGQDVVLNPTTVYGISKMAGEKWCEYYHDKYGVDVRSI 171

		            ++ + + SS +V+G          D V +P ++Y  +K A E     Y   YG+    +

		Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176

		

		Query: 172 RY-----PGLISWKAPAGGGTTDYAVEIFYEAVEKGE-YQCFISENTAMPMLYMDDAINA 225

		           R+     P    W  P      D A+  F +A+ +G+    +          Y+DD   A

		Sbjct: 177 RFFTVYGP----WGRP------DMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEA 226

		

		Query: 226 TIKLMQEPAENISVWGS--------------YNLGGMSFTP-AELTNEI-----KKVMPN 265

		            I+L        + W                YN+G  S     +    +      +   N

		Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKN 286

		

		Query: 266 FKISYQPDFRQSIADSWPASIDDSKAKEDWGLSYEFDIK 304

		                  D  ++ AD+           E  G + E  +K

		Sbjct: 287 MLPLQPGDVLETSADT-------KALYEVIGFTPETTVK 318

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 31.0 bits (70), Expect = 0.007

		 Identities = 13/72 (18%), Positives = 23/72 (31%), Gaps = 10/72 (13%)

		

		Query: 163 VYLRF----GRPAVPVFMPEDMPFEIGKGILLQEGKDVTIVATGHLVW-ESLVAAEQL-- 215

		           V   F    G   +      + P   G  +  +  +   IVA    V+   +  A ++  

		Sbjct: 786 VRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQV 845

		

		Query: 216 ---EKEGISCEV 224

		              E+E   C  

		Sbjct: 846 KWGEEENAHCVA 857

		

		

		>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature.

		          Length = 393

		

		 Score = 26.5 bits (58), Expect = 0.019

		 Identities = 9/26 (34%), Positives = 18/26 (69%)

		

		Query: 55  FNFLLVFGTAEDRTNFITNELPNITM 80

		           FN + +FG  E+++   TN +PN+++

		Sbjct: 153 FNLVGLFGDNENQSTVKTNSVPNMSL 178

		

		

		>PF02370#M protein repeat

		          Length = 168

		

		 Score = 28.9 bits (64), Expect = 0.026

		 Identities = 27/142 (19%), Positives = 53/142 (37%), Gaps = 26/142 (18%)

		

		Query: 298 KLHDYYFELKNEHNLYFSKSLKDTLKIETIDHS--------EANQRLKYEENRLKIQQQI 349

		           KL   Y +L  E++    +  +     ++   +          NQ L+  E + + + + 

		Sbjct: 14  KLITEYNKLVEENSKLQKQLEEYLDSSDSKRENDPQYRALMGENQDLRKREGQYQDKIEE 73

		

		Query: 350 LEKQTQIAQEEANIKAINE------PYYKALEEIKTAKQKLATE----TDSYQINELKNQ 399

		           LEK+ +  QE    +   E       Y +  ++ +  +Q+L  E        QI++   Q

		Sbjct: 74  LEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQEQQQLEAEKQKLAKEKQISDASRQ 133

		

		Query: 400 IIT--------LQKYLENNHPK 413

		            +          +K LE  H K

		Sbjct: 134 GLNRDLEASRAAKKELEPKHQK 155

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score =  129 bits (324), Expect = 7e-33

		 Identities = 58/393 (14%), Positives = 122/393 (31%), Gaps = 54/393 (13%)

		

		Query: 344 KFRYNTIALDIEYCK-----KTTHEWKSLNENSLYLELQKK---GIKISINNLIAILKSE 395

		              ++ +       +     K     +  +   L   ++     G   +     AI  + 

		Sbjct: 468 CVAFDELREQPVAVRAFPWRKAPGPLEDADVLRLADYVETTYGTGEASAQTTEQAINVAA 527

		

		Query: 396 FVPHYNPIQEYFENLPKWDGK-------TDYISNLANYVYPLDREKFNHHFKKWAVRTVK 448

		            +   +P +++ +   +WD            +    +   P          K   +  V 

		Sbjct: 528 DMNRVHPFRDWVKAQ-QWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVA 586

		

		Query: 449 CALLERYFNKQAFVLV-HKAQNSGKSSFCRFLCPPELSQYLAEDISNDKDARILLCKNFL 507

		             ++E    K  + +V       GKS+    L   +       DI   KD+   +     

		Sbjct: 587 -RVMEPGC-KFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVA 644

		

		Query: 508 INLDELSSLAKKEINTLKSYFSKDQINERLPYDRKNSILPRICSFIGSTNRDTFLDDETG 567

		             L E+++  + +   +K++FS  +   R  Y R     PR      +TN+  +L D TG

		Sbjct: 645 YELSEMTAFRRADAEAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIWCTTNKRQYLFDITG 704

		

		Query: 568 SVRWLCFQITG---INW--NYRQECNIDLFWSQAYALAFD------------NNFNSEMT 610

		           + R+    + G   + W   +R +      +++A  L                 F  E  

		Sbjct: 705 NRRFWPVLVPGRANLVWLQKFRGQ-----LFAEALHLYLAGERYFPSPEDEEIYFRPEQE 759

		

		Query: 611 LEEIQD-NEDRNKKYQI-------LSTEQELIASNYKPAQENEGVFVTSTDVLIRLSELG 662

		           L  ++   + R                 Q+  + N       + V     D   + S + 

		Sbjct: 760 LRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTIADLVQALGADP-GKSSPML 818

		

		Query: 663 VRLSSVQIGKAFNALGFERKKHKTKQTYGYWVK 695

		                 Q+    N  G+E  +  + Q    +++

		Sbjct: 819 EG----QVRDWLNENGWEYLRETSGQRRRGYMR 847

		

		

		>ALARACEMASE#Alanine racemase signature.

		          Length = 356

		

		 Score = 31.3 bits (71), Expect = 0.009

		 Identities = 14/91 (15%), Positives = 36/91 (39%), Gaps = 19/91 (20%)

		

		Query: 275 GVAIGETALDTYKKAFECDPVSIFGGIVAMNYTVDKDTAEELNKTFLEIVMATDFDAEAL 334

		            +   E A+ T ++     P+ +  G             E  ++  L   + +++  +AL

		Sbjct: 57  ALLNLEEAI-TLRERGWKGPILMLEGFF------HAQDLEIYDQHRLTTCVHSNWQLKAL 109

		

		Query: 335 EVLSKKKNLRIIKIKNPVSDRQVWVKIDGGM 365

		           +           ++K P+    +++K++ GM

		Sbjct: 110 Q---------NARLKAPL---DIYLKVNSGM 128

		

		

		>DNABINDINGHU#Prokaryotic integration host factor signature.

		          Length = 91

		

		 Score = 31.6 bits (72), Expect = 2e-04

		 Identities = 22/86 (25%), Positives = 37/86 (43%), Gaps = 6/86 (6%)

		

		Query: 36  TDLTKDIEKISTVSGADIRAVLYALVDVMQSSLASGQIVRLGELGSLRVSFSSEGKA--- 92

		            DL   + + + ++  D  A + A+   + S LA G+ V+L   G+  V   +  K    

		Sbjct: 5   QDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGRNP 64

		

		Query: 93  -TEKEVTASAIKQAKVIFTPAKGIKD 117

		            T +E+   A K     F   K +KD

		Sbjct: 65  QTGEEIKIKASKVPA--FKAGKALKD 88

		

		

		>SUBTILISIN#Subtilisin serine protease family (S8) signature.

		          Length = 326

		

		 Score =  163 bits (414), Expect = 8e-48

		 Identities = 74/267 (27%), Positives = 114/267 (42%), Gaps = 25/267 (9%)

		

		Query: 277 DYSEKYYGNNHYEGPDAQHGTHVAGIIAGYPHGKEVQYGVASKVAKIMTVRAV-PDGDER 335

		           ++++   G+         HGTHVAG IA   +   V  GVA + A ++ ++ +   G  +

		Sbjct: 68  NFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGV-VGVAPE-ADLLIIKVLNKQGSGQ 125

		

		Query: 336 DKDVANAIRYAVDNGAKILNMSFGKPVSPGKKYVWDAFKYAQEKGVLLVKAAGNDNENIE 395

		              +   I YA++    I++MS G P       + +A K A    +L++ AAGN+ +  +

		Sbjct: 126 YDWIIQGIYYAIEQKVDIISMSLGGPEDV--PELHEAVKKAVASQILVMCAAGNEGDGDD 183

		

		Query: 396 E--NVYYPTNFYKPTDEKPFINNMIVVGASTNDNEFLRAGFSNYNGKMVDVFAPGDKIYS 453

		               + YP             N +I VGA   D     + FSN     VD+ APG+ I S

		Sbjct: 184 RTDELGYPGC----------YNEVISVGAINFDRH--ASEFSNS-NNEVDLVAPGEDILS 230

		

		Query: 454 TVPDGKYEYLQGTSMASPVVAGAAAVLLAYMPNLTPEQIIESLVKTANKSTVNAMTNSNT 513

		           TVP GKY    GTSMA+P VAGA A++           + E  +          + NS  

		Sbjct: 231 TVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPK 290

		

		Query: 514 NNRFDLI-----SRAGGVIDTYKAAEY 535

		                L+          + DT + A  

		Sbjct: 291 MEGNGLLYLTAVEELSRIFDTQRVAGI 317

		

		

		

		 Score = 39.4 bits (92), Expect = 2e-05

		 Identities = 19/88 (21%), Positives = 30/88 (34%), Gaps = 14/88 (15%)

		

		Query: 24  DKDAETWYHKDFSTTNVYGVNTNNAYKFLESKGLKPKTVVVGVLDSGVEVDHPGLAKNMW 83

		            +  +     +     V  +     +     +G     V V VLD+G + DHP L   + 

		Sbjct: 10  YQVIKQEQQVNEIPRGVEMIQAPAVWNQTRGRG-----VKVAVLDTGCDADHPDLKARII 64

		

		Query: 84  KNPNEVPNNGID----DDGNGYIDDIHG 107

		              N   ++  D     D NG     HG

		Sbjct: 65  GGRNFTDDDEGDPEIFKDYNG-----HG 87

		

		

		>PF07132#Harpin protein (HrpN)

		          Length = 356

		

		 Score = 35.4 bits (81), Expect = 0.002

		 Identities = 25/105 (23%), Positives = 37/105 (35%)

		

		Query: 949  QSKGITNVSDELKQLEEVNMKLKDILAKKFAKVSEVAGQLGGAFSELGGALKEYDEGLGD 1008

		            Q+ G  + S    Q   +  +L DI+       S + G LGG    LG +L     GL  

		Sbjct: 30   QNGGSPSQSAFGGQRSNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLG 89

		

		Query: 1009 TVESMGELLNVASDVAGALADFASGPQGIVGGIMKTIKAITSIFS 1053

		                 G   ++ S +  AL     G  G     M     + S+  

		Sbjct: 90   GGLGGGLGSSLGSGLGSALGGGLGGALGAGMNAMNPSAMMGSLLF 134

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 28.1 bits (62), Expect = 0.013

		 Identities = 16/81 (19%), Positives = 35/81 (43%), Gaps = 5/81 (6%)

		

		Query: 1  MAKKGRLSNKEREQK-KEYAKILFLQE--KNITIKDLAERVGVSVNTLTEWIKSGKWREL 57

		          MA+K +   +E  Q   + A  LF Q+   + ++ ++A+  GV+   +    K     +L

		Sbjct: 1  MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDK--SDL 58

		

		Query: 58 KRNILLTRQEQLVQMQDELVE 78

		             I    +  + +++ E   

		Sbjct: 59 FSEIWELSESNIGELELEYQA 79

		

		

		>TONBPROTEIN#Gram-negative bacterial tonB protein signature.

		          Length = 239

		

		 Score = 33.0 bits (75), Expect = 0.002

		 Identities = 9/44 (20%), Positives = 15/44 (34%)

		

		Query: 369 AQTENKEPETEEDEESKETEETKEETQAEKPKQKTPKKQKVQAK 412

		            Q     PE   + E +     +   +A    +K   K K + K

		Sbjct: 58  PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 101

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 29.0 bits (65), Expect = 0.006

		 Identities = 11/35 (31%), Positives = 18/35 (51%), Gaps = 1/35 (2%)

		

		Query: 60  KMEEKDPDFDYLEMPADLRFEVF-WNLYGYKKGKI 93

		            ++ KD  F  +   A ++ E F +  YGY  GK+

		Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKV 405

		

		

		>FbpA_PF05833#Fibronectin-binding protein

		          Length = 577

		

		 Score = 30.2 bits (68), Expect = 0.033

		 Identities = 15/92 (16%), Positives = 33/92 (35%), Gaps = 7/92 (7%)

		

		Query: 562 NQNGEKYFVAYAEPKRSFEVVPKLMPDGEKEQAQKDMRVAELEYQRDLQLLRDLEKKTGI 621

		           +QN + Y+  Y + K+S E   + +   E+E       +  +    +   + +++     

		Sbjct: 380 SQNVQSYYKKYNKLKKSEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIK----- 434

		

		Query: 622 STERLIAEQEMAVKTQNINSKKLNIKADRGES 653

		             + LI    +  K    + K    K     S

		Sbjct: 435 --KELIETGYIKFKKIYKSKKSKTSKPMHFIS 464

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 30.7 bits (69), Expect = 0.019

		 Identities = 16/52 (30%), Positives = 24/52 (46%), Gaps = 1/52 (1%)

		

		Query: 235 QVAITNEYVLLYSKSDELVLNEMPKEVDFKFYDSKGGYILRELRNRNPKFHS 286

		           Q+ I N+  L++   +   L       +F  +D KG  I R  +N  PKF S

		Sbjct: 306 QIEIENKDNLIWHLHNTAHLYRQELFTEFILFDQKGNTI-RNFQNIFPKFVS 356