>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.2 bits (68), Expect = 0.006 Identities = 9/51 (17%), Positives = 24/51 (47%) Query: 138 LHAVDARVNELEELLPLLMKDKLLAKGVSHLLSSQLTRILRTHAAMSVLGH 188 + V+ +VN+ +P L + + +++ +S L +S + + A + Sbjct: 80 VSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSE 130
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 142 bits (361), Expect = 7e-40 Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 84/387 (21%) Query: 5 IGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58 + IDLGT N+ + + + E PS++A QD VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAE 118 P N + AI+ + +D I F + + Sbjct: 64 GRTPGN-IAAIRPM-----------KDGVIADFFVTEK------------------MLQH 93 Query: 119 VLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALA 178 +K++ + P ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 94 FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 179 YGL--DKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236 GL + TG+ V D+GGGT ++++I ++ V + +GG+ FD + Sbjct: 151 AGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAI 198 Query: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADATG 292 INY+ + G + AE+ K E+ SA + ++ + Sbjct: 199 INYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245 Query: 293 PKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIDD--VILVGGQTRMPMV 349 P+ + + LE+L E + + + VAL+ SDI + ++L GG + + Sbjct: 246 PRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303 Query: 350 QKKVAEFFGKEPRKDVNPDEAVAIGAA 376 + + E G +P VA G Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGG 330
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 26.6 bits (59), Expect = 0.042 Identities = 13/29 (44%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 2 SKYIYILLSF-LVLFFIFFYAYISLMSKE 29 IYI+ F L++FF FFY IS +E Sbjct: 314 DHPIYIVTYFLLIVFFAFFYVAISFNPEE 342
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.014 Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 5/80 (6%) Query: 4 RRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWVAVWQDS-YLWHVVRFSFWQ 62 R GWL + L V A +W+ A ++W+ ++ Sbjct: 60 RSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVAN----TSIWRLLAFINTKPVAFTLP 115 Query: 63 AFLSAQLSVVPAIFLARALY 82 LS +VV F+ LY Sbjct: 116 LALSIIFNVVVVTFMWSLLY 135
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 26.0 bits (57), Expect = 0.019 Identities = 13/34 (38%), Positives = 20/34 (58%) Query: 1 MYNFKDKIEDYTEREFIELLGEFTNPTGDNAQLK 34 Y+ K+ I+D ++F + L EFT T N +LK Sbjct: 88 QYSLKETIQDLCAKDFHQKLKEFTEKTPKNQKLK 121
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.018 Identities = 27/100 (27%), Positives = 40/100 (40%), Gaps = 22/100 (22%) Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDRLL- 164 V +E G L + V L AV GL P +V + D++G LL Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSG-HLLT 220 Query: 165 -SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203 S+ + AQL V + +RI L+ P++G G Sbjct: 221 QSNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 807 bits (2085), Expect = 0.0 Identities = 263/869 (30%), Positives = 429/869 (49%), Gaps = 40/869 (4%) Query: 12 IATFCALLYSNSALCAELVEYDHTFLMGKDASNIDLSRYTEGNPTLPGIYDVSVYVNDQP 71 + CA AE + ++ FL + DLSR+ G PG Y V +Y+N+ Sbjct: 30 LFVACAFAAQAPLSSAE-LYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88 Query: 72 IMSQSIAFAVIEGKKNAQACITQKNLLQFHISSPDKNSEKAILLKRDDDLGDCLNLAEMI 131 + ++ + F + ++ C+T+ L +++ + + C+ L MI Sbjct: 89 MATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLL------ADDACVPLTSMI 142 Query: 132 PQSSIRYDVNDQRLDIDVPQAWIMKNYQNYVDPSLWENGINAAMLSYNLNGYHSESP-GR 190 ++ + DV QRL++ +PQA++ + Y+ P LW+ GINA +L+YN +G ++ G Sbjct: 143 HDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGG 202 Query: 191 TNDSIYAAFNGGINLGAWRLRASGNYNWMTNVHS-----DYDFQNRYLQRDLASLRSQLV 245 + Y G+N+GAWRLR + +++ ++ S + N +L+RD+ LRS+L Sbjct: 203 NSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLT 262 Query: 246 IGESYTTGETFDSVSIRGIRLYSDSRMLPPVLASFAPIIHGVANTNAKVTVMQNGYKIYE 305 +G+ YT G+ FD ++ RG +L SD MLP FAP+IHG+A A+VT+ QNGY IY Sbjct: 263 LGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYN 322 Query: 306 TTVPPGAFAIDDLSPSGYGSDLIVTIEEADGTKRTFSQPFSSVVQMLRPGVGRWDISAGQ 365 +TVPPG F I+D+ +G DL VTI+EADG+ + F+ P+SSV + R G R+ I+AG+ Sbjct: 323 STVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGE 382 Query: 366 VLKD-SIQDEPNLFQASYYYGLNNYLTGYTGIQLTDNNYTAGLLGLGMNT-PVGAFSVDV 423 + Q++P FQ++ +GL T Y G QL D Y A G+G N +GA SVD+ Sbjct: 383 YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVDM 441 Query: 424 THSNVSIPDDKTYQGQSYRISWNKLFENTSTSLNIAAYRYSTQHYLGLNDALTLIDEVEH 483 T +N ++PDD + GQS R +NK + T++ + YRYST Y D + Sbjct: 442 TQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYN 501 Query: 484 PE-----QDLEPKSMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASGQ 535 E ++PK Y+ + ++ +++ Q L + YLSGS YW + Sbjct: 502 IETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTSN 557 Query: 536 NSTNYSIGYSNSASWGSYSISAQRSLNE-DGQTDDSIYLSFTIPIENLLGTEHRSS-GFQ 593 + G + + ++++S + N D + L+ IP + L ++ +S Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 594 SIDTQLNSDFKGNNQLNISSSGYSDT-NRISYSVNTGYMMNKSSDDLSYIGGYASYESPW 652 S ++ D G G N +SYSV TGY + S +Y + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 653 GTLSGSASASSDNSRQFSLNTDGGFVLHSGGLTFSNDSFSDSDTLAVIQAPGAKGARINY 712 G + S S D +Q GG + H+ G+T +DT+ +++APGAK A++ Sbjct: 678 GNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVEN 733 Query: 713 GNST-VDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSTVAVPRQGAVVFADFETV 771 D GY V + Y ENR+ALD N L ++V+L + VP +GA+V A+F+ Sbjct: 734 QTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKAR 793 Query: 772 QGQSAIMNIVRSDGKNIPFAADIYDEQNNIIGNVGQGGQAFVRGIEQEGNIRITWIEEGK 831 G +M + + K +PF A + E + G V GQ ++ G+ G +++ W EE Sbjct: 794 VGIKLLMT-LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 832 PVSCFAHYQQNTTSEKIAQSIILNGLRCQ 860 C A+YQ S++ Q + C+ Sbjct: 853 A-HCVANYQLPPESQQ--QLLTQLSAECR 878
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 509 bits (1312), Expect = 0.0 Identities = 293/296 (98%), Positives = 294/296 (99%) Query: 2 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAVIDPNRIVALEWLPVELLLALGIVPYGVA 61 MSGLPLISRRRLLTAMALSPLLWQMNTAHAA IDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 62 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 121 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 122 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYEDFIRSMKPRFVKRGARPLLLT 181 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLA YEDFIRSMKPRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 182 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 241 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 242 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRILDNAIGGKA 297 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVR+LDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 34.3 bits (78), Expect = 5e-04 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236 + ++ EL A N T+ +K ++N+ +R D + I V +E+++++ Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 6e-04 Identities = 9/74 (12%), Positives = 29/74 (39%), Gaps = 8/74 (10%) Query: 16 LRQKDQQLSLVEETKTFLRSALARAEEKIEEDEREIEHLRA--QIEKLRRMLFGTCSEKL 73 L + ++ +R +L + + E+ + + Q+ ++ F ++L Sbjct: 187 LEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQ---FE---DRL 240 Query: 74 RREVEQAEALLKQR 87 + E + A++ + Sbjct: 241 QFENQINPAIMDVQ 254
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.034 Identities = 8/39 (20%), Positives = 18/39 (46%), Gaps = 1/39 (2%) Query: 84 NGAQFRQLCETTDWVDAGE-NVLLFGASGLGKSHLAAAI 121 A +++ + + +++ G SG GK +A A+ Sbjct: 142 RSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.002 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 VTVLLGPNGCGKSTLLRALAGL 53 VL G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (333), Expect = 1e-39 Identities = 77/262 (29%), Positives = 131/262 (50%), Gaps = 14/262 (5%) Query: 4 INMFSLKGKNALVTGASYGIGFEIAKALSNAGATIIFNDVIEENIKKGLAAYKENNINAH 63 +N ++GK A +TGA+ GIG +A+ L++ GA I D E ++K +++ K +A Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 64 GYLFDITDEQSVKENIKKIESDVGIIDILVNNAGIIQRKPMLETTAADYRKIIDIDLTGQ 123 + D+ D ++ E +IE ++G IDILVN AG+++ + + ++ ++ TG Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 124 FIMAKAVLPSMIKKGHGKIINICSMMSELGRETVVGYASAKGGLKMLTKNICSEFGEKNI 183 F +++V M+ + G I+ + S + + R ++ YAS+K M TK + E E NI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 184 QCNGIGPGYIAT--------PQTAPLREIQPDGSRHPFDQFIISKTPAGRWGKPDDLAGA 235 +CN + PG T + + I+ + F P + KP D+A A Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSL-----ETFKTG-IPLKKLAKPSDIADA 234 Query: 236 AIFLASDASNFINGHILYVDGG 257 +FL S + I H L VDGG Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256
>PF05860#haemagglutination activity domain. Length = 117 Score = 74.1 bits (182), Expect = 2e-17 Identities = 25/139 (17%), Positives = 44/139 (31%), Gaps = 26/139 (18%) Query: 32 AVITPQNGA---GMDKAANGVPVVNIATPNGAGISHNRFTDYNVGKEGLILNNATGKLNP 88 A ITP ++ T G+ + H+ F +++V G N Sbjct: 1 AQITPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPT---- 55 Query: 89 TQLGGLIQNNPNLKAGGEAKGIINEVTGGKRSLLQGYTEVAGKAANVMVANPYGITCDGC 148 + II+ VTGG S + G A N+ + NP GI Sbjct: 56 -----------------NIQNIISRVTGGSVSNIDGLIRANATA-NLFLINPNGIIFGQN 97 Query: 149 GFINTPHATLTTGKPVMNA 167 ++ + + + + Sbjct: 98 ARLDIGGSFVGSTANRLKF 116
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 738 bits (1906), Expect = 0.0 Identities = 260/862 (30%), Positives = 401/862 (46%), Gaps = 116/862 (13%) Query: 53 SQAGIVRSDIAYQIYRDFAENKGLFVPGATDIPVYDKDGKLVGRL--DKAPMADFSSVSS 110 ++A +VR D+ YQI+RDFAENKG F GAT++ V DK+ K +G + PM DFS V Sbjct: 23 TEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNGIPMIDFSVVDV 82 Query: 111 N-GVATLVSPQYIVSVKH-NGGYQSVSFGN------------------GKNTYSLVDRNN 150 + +ATL++PQY+V VKH + G + FGN +N Y V++N Sbjct: 83 DKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVSSEENRYFSVEKNE 142 Query: 151 HSSV-----------------DFHAPRLNKLVTEVIPSAITSEGTKANAYKDTERYTAFY 193 + + D++ PRL+K VTEV P ++ + A Y D +Y AF Sbjct: 143 YPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDAGTYNDQNKYPAFV 202 Query: 194 RVGSGTQYTKDKDGNLVKVAGGYAFKTGGTTGVPLISDATIVSNPGQTYNPVNG------ 247 R+GSG+Q+ K N + + V I P + + NG Sbjct: 203 RLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYKVNHENNGLIGFGN 262 Query: 248 ---------------PLPDYGAPGDSGSPLFAYDEQQKKWVIVAVLRAYAGINGAT-NWW 291 PL +Y GDSGSPLF YD ++ KW+ + +AG N + W Sbjct: 263 SKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYDFWAGYNKKSWQEW 322 Query: 292 NVIPTDYLNQVMQDDFDAPVDFVSGLPPLNWTYDKTSGTGTLSQGSKNWTMHGQKDNDLN 351 N+ + + V+ D + + +W+ + + T T + S N + KD N Sbjct: 323 NIYKSQFTKDVLNKD--SAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKDKP-N 379 Query: 352 AGKNLVFSGQNGAIVLKDSVTQGAGYLEFKDSYTVSAES-GKTWTGAGIITDKGTNVTWK 410 GK++ F G +G + L +++ QGAG L F+ Y V S TW GAG+ +G VTWK Sbjct: 380 HGKSVTFEG-SGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWKGAGVSVAEGKTVTWK 438 Query: 411 VNGVAGDNLHKLGEGTLTINGTGVNPGGLKTGDGTVVLNQQADTAGNVQAFSSVNLASGR 470 V+ D L K+G+GTL + GTG N G LK GDGTV+L QQ + +G AF+SV + SGR Sbjct: 439 VHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQ-HAFASVGIVSGR 497 Query: 471 PTVVLGDARQVNPDNISWGYRGGKLDLNGNAVTFTRLQAADYGAVITN-NAQQKSRLLLD 529 T+VL D +QV+P++I +G+RGG+LDLNGN++TF ++ D GA + N N S + + Sbjct: 498 STLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGARLVNHNMTNASNITIT 557 Query: 530 LKAQDT--------NVSVP-IGSISPFGGTGTPGNLYSMILNGQTRFYILKSASYGNTLW 580 ++ T N+ P + F G LY + L T + + K AS + L Sbjct: 558 GESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLY-LNLENYTYYALRKGASTRSELP 616 Query: 581 GNSLNDPAQWEFVGTDKNKAVQTVKDRILAGRAKQPVIF----HGQLTGNMDVTIPQLPG 636 NS W ++G ++A + V + I R + G+ GN++VT Sbjct: 617 KNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSE 676 Query: 637 GRKVILDGSVNLPEGTLSEDSGTLIFQGHPVIHA-SVSGSAPVSLN-----------QKD 684 + +L G NL G L+ + GTL G P HA ++G + + + D Sbjct: 677 QNRFLLTGGTNL-NGDLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDD 735 Query: 685 WENRQFIMKTLSLK-DADFHLSRN-ASLNSDIKSDNS---HITLGSDRVFVDKNDGTGNY 739 W NR F T+++ +A + RN A++ S+I + N HI + ++D TG Sbjct: 736 WINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGY- 794 Query: 740 VILEEGTSVPDTVNDR-------SQYEGNITLDHNSTLDIGSR--FTGGIEAYDSAVSIT 790 T D ++D+ + GN+ L ++ +G F +S V +T Sbjct: 795 -----VTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLT 849 Query: 791 SPDVLLTAPGAFAGSSLTVHDG 812 + G L + +G Sbjct: 850 E-NSHWHLTGNSDVHQLDLANG 870 Score = 80.1 bits (197), Expect = 4e-17 Identities = 41/154 (26%), Positives = 65/154 (42%), Gaps = 18/154 (11%) Query: 864 DNATLEITRGAHASGDIHASAASTVTIGSDTPAELASAETTASAFAG--------SLLEG 915 + A + I + + + VT +D ++ A + G + + G Sbjct: 771 NKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGNVNLTESANFVLG 830 Query: 916 YNAAFNGAITGGRADVSM-HNALWTLGGDSAIHTLTVRNSRI------SSEGDRTFRTLT 968 F + G + V + N+ W L G+S +H L + N I +S + TLT Sbjct: 831 KANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLT 890 Query: 969 VNKLDATGSDFVLRTDLKN--ADKINVTEKATGS 1000 VN L GS + L TDL N DK+ VT+ ATG+ Sbjct: 891 VNSLSGNGSFYYL-TDLSNKQGDKVVVTKSATGN 923
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 234 bits (598), Expect = 2e-74 Identities = 88/430 (20%), Positives = 179/430 (41%), Gaps = 64/430 (14%) Query: 45 LMVIFLLVLVVTFVIWAWNSPLDEVTRGQGSIIPGSREQVIQTLDPGILKTLEVREGDIV 104 L+ F++ +V I + ++ V G + R + I+ ++ I+K + V+EG+ V Sbjct: 59 LVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESV 118 Query: 105 EKGQVLLTLDDTRSSAMLRESEARVNNLEAVRARLRAEAYS------ESLTFPDD-VPAD 157 KG VLL L + A ++++ + + R + + S L PD+ + Sbjct: 119 RKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 158 LRERESTVYR--------LRKTELAQS-----------------IAGLKQSKALLDKEIA 192 + E E + + Q I + + + Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Query: 193 MTRPIVREGAMSEVELLRMQRQSAEL---------------------QLQMDEKQNKYLT 231 ++ + A+++ +L + + E + + + Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 232 EAGAELVKTEAELAQAKENMAGRADPVERSRIRAPLRGIVKNIRVNTLGGVVSAGQDIME 291 E +L +T + +A + + S IRAP+ V+ ++V+T GGVV+ + +M Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Query: 292 IIPLEDQLLIEAYINPRDVAYVRTGMPALVKLTAYDYAIYGGLDGVVTLVSPDTLRDQKR 351 I+P +D L + A + +D+ ++ G A++K+ A+ Y YG L G V ++ D + DQ+ Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQR- 417 Query: 352 PGDLKLDPNEAYYRVLVTTSNNYLTDRNGKILPVIPGMIASVDIKTGQKSVFQYLIKPIT 411 + V+++ N L+ K +P+ GM + +IKTG +SV YL+ P+ Sbjct: 418 --------LGLVFNVIISIEENCLS-TGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLE 468 Query: 412 -RMKQALQER 420 + ++L+ER Sbjct: 469 ESVTESLRER 478
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 47.7 bits (113), Expect = 3e-07 Identities = 32/192 (16%), Positives = 58/192 (30%), Gaps = 25/192 (13%) Query: 1327 NNIDTATDVNTVTIYGSVSGEILGGYGSDNITVTKNLTGNISVGDNADTLTAGWIYGGST 1386 N+ T T + + + S + ++ DT Sbjct: 260 ANMTTRTGDSVYGFNSNTDRDFYTATDSSKALI-----FSVWDAGGTDTFDFSGYSNNQR 314 Query: 1387 VSMGDGNDT--------VTITDGAYNTTISLGAGDDVFDATSGVMGDSAYATVVNGEDGN 1438 +++ +G+ + V+I G G+G+D+ S ++ G GN Sbjct: 315 INLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSA-------DNILQGGAGN 367 Query: 1439 DTFKLGTIAKNLTIDAGAGDDIVVLTKDYDSTSSGN---QGYINGGEGSDTLVLTGTISV 1495 D G A T+ GAG D V DST + + G + D + Sbjct: 368 DVLYGG--AGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQL 425 Query: 1496 NLAAGKNEGIAG 1507 + + G Sbjct: 426 SFVQDQFTGKGQ 437
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 614 bits (1585), Expect = 0.0 Identities = 267/886 (30%), Positives = 407/886 (45%), Gaps = 123/886 (13%) Query: 42 SLALSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAGATNIPIFNNKGELVGHL--DK 99 +L ++ L A+ V + YQ +RDFAENKG+F GATN+ + + + +G + Sbjct: 12 ALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNKDLGTALPNG 71 Query: 100 APMVDFSSVNVSSNPGVATLINPQYIASVKH-NKGYQSVSFG------------------ 140 PM+DFS V + +ATLINPQY+ VKH + G + FG Sbjct: 72 IPMIDFSVV--DVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNAKAHRDVS 129 Query: 141 DGQNSYHIVDRNEHSSS-----------------DLHTPRLDKLVTEVAPATVTSSST-- 181 +N Y V++NE+ + D + PRLDK VTEVAP +++S+ Sbjct: 130 SEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEASTASSDA 189 Query: 182 ADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYGYLTGGILPTSFFYH--------- 232 + +KY AF R GSGSQ+I + + + Y Sbjct: 190 GTYNDQNKYPAFVRLGSGSQFIYKKGDNYSLILNNHEVGGNNLKLVGDAYTYGIAGTPYK 249 Query: 233 --GSDGIQLYMGGNIHDHSI---------LPSFGEAGDSGSPLFGWNTAKGQWELVGVYS 281 + + G + +HS L ++ GDSGSPLF ++ KG+W +G Y Sbjct: 250 VNHENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSPLFVYDREKGKWLFLGSYD 309 Query: 282 ---GVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAPLQWKFDSSTGTGSLKQGS 338 G + +++ F + ++D+ + + + + S+ T ++ G Sbjct: 310 FWAGYNKKSWQEWNIYKSQFTKDVLNKDSAGSLIGSK-----TDYSWSSNGKTSTITGGE 364 Query: 339 DEYAMHGQKGSDL-NAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVT-TSNGSTWT 396 + G D N GK++TF G +G + L N++ QGAG L F DY V TS+ +TW Sbjct: 365 KSLNVDLADGKDKPNHGKSVTFEG-SGTLTLNNNIDQGAGGLFFEGDYEVKGTSDNTTWK 423 Query: 397 GAGIIVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSS 456 GAG+ V + +V W+V+ + D L KIG+GTL+V+GTG N+G LKVGDGTV+L QQ + S Sbjct: 424 GAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGS 483 Query: 457 GHVQAFSSVNIASGRPTVVLADNQQVNPDNISWGYRGGVLDVNGNDLTFHKLNAADYGAT 516 G AF+SV I SGR T+VL D++QV+P++I +G+RGG LD+NGN LTF + D GA Sbjct: 484 GQ-HAFASVGIVSGRSTLVLNDDKQVDPNSIYFGFRGGRLDLNGNSLTFDHIRNIDDGAR 542 Query: 517 LGNS-SDKTANITLD---YQTRPADVKV---------NEWSSSNRGTVGSLYIYNNPYTH 563 L N +NIT+ T P + N ++ G LY+ YT Sbjct: 543 LVNHNMTNASNITITGESLITDPNTITPYNIDAPDEDNPYAFRRIKDGGQLYLNLENYT- 601 Query: 564 TVDYFILK--TSSYGWFP-TGQVSNEHWEYVGHDQNSAQALLANRINNK------GYLY- 613 Y+ L+ S+ P SNE+W Y+G + A+ + N INN+ GY Sbjct: 602 ---YYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNVMNHINNERMNGFNGYFGE 658 Query: 614 -HGKLLGNINFSNKATPGTTGALVMDGSANMSGTFTQENGRLTIQGHPVIHASTSQSIAN 672 GK GN+N + K ++ G N++G T E G L + G P HA + IA Sbjct: 659 EEGKNNGNLNVTFKGKSE-QNRFLLTGGTNLNGDLTVEKGTLFLSGRPTPHA---RDIAG 714 Query: 673 TVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLK-DTDFGLGRN-ATLNTTIQADNSS- 729 S+ D +DDW NR F ++ + + GRN A + + I A N + Sbjct: 715 ISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTGNASLYSGRNVANITSNITASNKAQ 774 Query: 730 ----VTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQS--VLNINE 783 GD+ G T T ++ + A + + G VNL + VL Sbjct: 775 VHIGYKTGDTVCVRSDYTGYVTC-TTDKLSDKALNSFNPTNLRGNVNLTESANFVLGKAN 833 Query: 784 IFNGGIQANNSTVNISSDS-------AVLENSTLTSTALNLNKGAN 822 +F NS V ++ +S + + L + ++LN N Sbjct: 834 LFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADN 879 Score = 53.9 bits (129), Expect = 5e-09 Identities = 65/329 (19%), Positives = 121/329 (36%), Gaps = 54/329 (16%) Query: 760 KDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNISSDSAVLENSTLTSTALNLNK 819 K +D++ N +++N+ + N F NN +N++ +N L + NLN Sbjct: 631 KTSDEAKRNVMNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNG 690 Query: 820 GANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSW----------NLKG 869 V F+S P + ++S + W N+ G Sbjct: 691 DLTVEKGTLFLSGRPTPHARDIAGISSTKKDPHFAENNEVVVEDDWINRNFKATTMNVTG 750 Query: 870 DDARLNVGPYSMLSGNINVQDKGTVTLG--------------GEGELSPDLTLQNQMLYS 915 + + + + ++ NI +K V +G G + D L ++ L S Sbjct: 751 NASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTD-KLSDKALNS 809 Query: 916 LFN-----------------GYRNTWSGSLNAPDATVSMT-DTQWSMNGNSTAGNMKLNR 957 G N + + ++ V +T ++ W + GNS + L Sbjct: 810 FNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLAN 869 Query: 958 TIVGFNGGTSS-----FTTLTTDNLDAVQSAFVMRTDL--NKADKLVINKSATGHDNSIW 1010 + N +S + TLT ++L +F TDL + DK+V+ KSATG+ Sbjct: 870 GHIHLNSADNSNNVTKYNTLTVNSLSG-NGSFYYLTDLSNKQGDKVVVTKSATGNFTLQV 928 Query: 1011 VNFLKKPSDKDTLDIPLVSAPEATADNLF 1039 + +P+ ++ L A +A D+L Sbjct: 929 ADKTGEPNHN---ELTLFDASKAQRDHLN 954
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 62.6 bits (152), Expect = 5e-12 Identities = 29/247 (11%), Positives = 73/247 (29%), Gaps = 23/247 (9%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSS 546 L + + T +S + Y + +Q+ + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYINTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFDTGLEN---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G ++ + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLD 718 + + + Sbjct: 762 TNTLADN 768
>INTIMIN#Intimin signature. Length = 939 Score = 548 bits (1413), Expect = e-178 Identities = 233/832 (28%), Positives = 355/832 (42%), Gaps = 78/832 (9%) Query: 41 PVMAARAQHAVQPRLSMENTTVTADNNVEKNVASLAANAGTFLSSQPDS-----DATRNF 95 P++AA +L+ + VT N + + AA L SQ S D ++ Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190 Query: 96 ITGMATAKANQEIQEWLGKYGTARVKLNVDKKFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155 G+A +A+ ++Q WL YGTA V L F SSL+ L P YD+ + F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 156 HRTDDRTQSNIGFGWRHFSENDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215 D R +N+G G R F + M G N FID D S +TR+G+G EYWRDY K S NGY Sbjct: 249 RYIDSRFTANLGAGQRFF-LPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307 Query: 216 IRASGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275 R SGW +S + +DY ERPANG+DIR GYLP++P LGA LMYEQYYGD V LF DK Q Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367 Query: 276 KDPHAITAEVNYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRER 335 +P A T VNYTP+PL+T+ ++ G END + ++ Y+ +P +Q++ + E Sbjct: 368 SNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNEL 427 Query: 336 RMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTVSLGLVVSKATHGLKNVQ 395 R L+GSRYDLV+RNNNI+LEY+K +++ + +P I G T + L+V K+ +GL + Sbjct: 428 RTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIV-KSKYGLDRIV 486 Query: 396 WEAPSLLAAGGKITGQG----NQWQVTLPAYQAGKDNYYAISAIAYDNKGNASKRVQTEV 451 W+ +L + GG+I G +Q LPAY G N Y ++A AYD GN+S V + Sbjct: 487 WDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTI 546 Query: 452 VISGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLR----DAEGQPVTGMKDQIKTE 507 + G D+ +T + A+G E +++ PV+ Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVS--------- 597 Query: 508 LTFKPAGNIVTRTLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDDMSK 567 NIV+ T + + A +G + G+ ++ +M+ Sbjct: 598 ------FNIVSGTAVLSANSAN-------TNGSGKATVTLKSDK-PGQVVVSAKTAEMTS 643 Query: 568 TVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLRLVP 627 + A + S VA+GQ A T T+ V PV+ + Sbjct: 644 ALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVK-VMKGDKPVSNQEVTF---- 698 Query: 628 QDTNGVTVGAIS--EIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP--- 682 T + + G T++ST G +V A + ++F Sbjct: 699 -TTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTID 757 Query: 683 ----------LDAAHSSITLNPDK---PVVGGTVTAIWTAKDANDNPVTGLNPDAPSLSG 729 + ++ L + GG W + + V + +L Sbjct: 758 DGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDA-SSGQVTLKE 816 Query: 730 AAAAGSTASGWTDNGDGTWTAQISLGTTAGELDVMPKLNGQDAAANAAKVTVVADALSSN 789 + +DN T+T T L V L S+ Sbjct: 817 KGTTTISVIS-SDNQTATYTIA-----TPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSS 870 Query: 790 QSKV-------SVAEDHVKAGESTTVTLVAKDAHGNAISGLSLSASLTGTAS 834 Q+++ A + S T+ + +A SG++ + L Sbjct: 871 QNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVASTYDLVKQNP 922 Score = 74.0 bits (181), Expect = 4e-15 Identities = 74/345 (21%), Positives = 113/345 (32%), Gaps = 42/345 (12%) Query: 905 KTTTELTFTVK----DAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTL 960 T TVK PV+ + SG A SA + G+G TL Sbjct: 575 TEAITYTATVKKNGVAQANVPVSFN-----IVSGTAV-----LSANSANTNGSGKATVTL 624 Query: 961 TLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITL 1020 + +A+ V+ V D +KA I ++ +ANGQ A IT Sbjct: 625 KSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASITEIKADKTTAVANGQDA--ITY 680 Query: 1021 TV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVDIELMSTVAGELEIEASVKN 1079 TV V P+ QEVT T G S + T T+ G + L ST G+ + A V + Sbjct: 681 TVKVMKGDKPVSNQEVTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSD 738 Query: 1080 SQKTVKVKFKADFSTGQASLEVDAA-AQKVANGKDAFTLTATVK-DQYGNLLPGAVVVFN 1137 VK F +L +D + V G T ++ Q G + Sbjct: 739 VAVDVKAPEVEFF----TTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYT 794 Query: 1138 LPRGVKPLADGNIMVNADKEGKAELKVVSVTAGTYEITASAGNDQPSNAQSVTFVADKTT 1197 A+ I G+ LK GT I+ + ++Q T+ Sbjct: 795 W-----RSANPAIASVDASSGQVTLK----EKGTTTISVISSDNQT-----ATYTIATPN 840 Query: 1198 ATISSIEVIGNRAVADGKTKQTYKVTVTDANNNLLKDSEVTLTAS 1242 + I + D ++ N L++ A+ Sbjct: 841 SLI-VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAA 884 Score = 54.7 bits (131), Expect = 2e-09 Identities = 46/249 (18%), Positives = 82/249 (32%), Gaps = 24/249 (9%) Query: 1168 TAGTYEITASA----GNDQPSNAQSVTFVADKTTAT---ISSIEVIGNRAVADGKTKQTY 1220 + Y++TA A GN + ++T +++ ++ A ADG TY Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580 Query: 1221 KVTVTDANNNLLKDSEVTLTASPENLVLTPNGTATTNEQGQAIFTATTTVAATYTLTAKV 1280 TV S + +A TN G+A T + ++AK Sbjct: 581 TATVKKNGVAQANVPVSFNIVS--GTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK- 637 Query: 1281 EQADGQESTKTAESKFVADDKNAVLAASPERVDSLVADGKTTATLTVTLMSGVNPVGGTM 1340 A+ + FV K ++ ++ + VA+G+ T TV +M G PV Sbjct: 638 -TAEMTSALNANAVIFVDQTKASITEIKADK-TTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 1341 WVDIEA--PEGVTEADYQFLPSKNDHFASGKITRTFSTNKPGTYTFTFNSLTYGGYEMKP 1398 + K D +G T ++ PG + ++ ++K Sbjct: 696 VTFTTTLGKLSNSTE-------KTD--TNGYAKVTLTSTTPGKSLVS-ARVSDVAVDVKA 745 Query: 1399 VTVTINAVP 1407 V Sbjct: 746 PEVEFFTTL 754 Score = 47.0 bits (111), Expect = 5e-07 Identities = 56/368 (15%), Positives = 104/368 (28%), Gaps = 56/368 (15%) Query: 779 VTVVADALSSNQSKV---SVAEDHVKAGESTTVTLVA------KDAHGNAISGLSLSASL 829 +TV+++ +Q V + + KA + +T A +S +S Sbjct: 546 ITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSG-- 603 Query: 830 TGTASEGATVSSWTEKGDGSYVAT--LTTGGKTGELRVMPLFNGQPAATEAAQLTVIAGE 887 A +S+ + +GS AT L + + A A + + Sbjct: 604 ------TAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN--ANAVIFVDQ 655 Query: 888 MSSANSTLVADNKTPTVKTTTELTFTVKDAY-GNPVTGLKPDAPVFSGAASTGSERPSAG 946 ++ + + AD T +T+TVK PV+ + +T + S Sbjct: 656 TKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEV-------TFTTTLGKLSNS 708 Query: 947 NWTEKGNGVYVSTLTLGSAAGQLSVMPRVNGQN-AVAQPLVLNVAG---DASKAEIRDMT 1002 NG TLT + G+ V RV+ V P V D EI Sbjct: 709 TEKTDTNGYAKVTLT-STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEI---- 763 Query: 1003 VKVNNQLANGQSANQITLTV-VDSYGNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKVDI 1061 + G T+ + G T ++ ++G+V + Sbjct: 764 ------VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTW---RSANPAIASVDASSGQVTL 814 Query: 1062 ELMSTVAGELEIEASVKNSQKTVKVKFKADFSTGQASLEVDAAAQKVANGKDAFTLTATV 1121 + G I ++Q + + + + Sbjct: 815 K----EKGTTTISVISSDNQ---TATYTIATPNSLIVPNMSKRVT-YNDAVNTCKNFGGK 866 Query: 1122 KDQYGNLL 1129 N L Sbjct: 867 LPSSQNEL 874
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.027 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 14 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 55 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 122 bits (307), Expect = 1e-30 Identities = 112/509 (22%), Positives = 187/509 (36%), Gaps = 73/509 (14%) Query: 330 LDINLSDSSVWKGKVSGAGDASVSLQNGSVWNVTGSSTVDALAVKDSTVNITKATVNTGT 389 LD+ L+ + W G S+S+ N W +T +S V AL + + G Sbjct: 413 LDVALASQARWTGATRAVD--SLSIDNA-TWVMTDNSNVGALRLASDGSVDFQQPAEAGR 469 Query: 390 FA-------SQNGTLI----VDASSENTLDISGKASGDLRVY---------SAGSLDLIN 429 F + +G D + L + ASG R++ SA +L L+ Sbjct: 470 FKVLTVNTLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQ 529 Query: 430 EQ----TAFISTGKDSTLKATGTTEGGLYQYDLTQGADGNFYFVKNTHK----------- 474 F KD G + G Y+Y L +G + V Sbjct: 530 TPLGSAATFTLANKD------GKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGP 583 Query: 475 -----------------------ASNASSVIQAMA-AAPANVANLQADTLSARQDAVRLS 510 ++ A++ + + + +++ LS R +RL+ Sbjct: 584 QPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLN 643 Query: 511 ENDKGGVWIQYFGGKQKHTTAGNASYDLDVNGVMLGGDTRFMTEDGSWLAGVAMSSAKGD 570 D GG W + F +Q+ +D V G LG D G W G +GD Sbjct: 644 P-DAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGD 702 Query: 571 MT-TMQSKGDTEGYSFHAYLSRQYNNGIFIDTAAQFGHYSNTADVRLMNGGGTIKADFNT 629 T G T+ Y + ++G ++D + N V +G +K + T Sbjct: 703 RGFTGDGGGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGY-AVKGKYRT 761 Query: 630 NGFGAMVKGGYTWKDGNGLFIQPYAKLSALTLEGVDYQL-NGVDVHSDSYNSVLGEAGTR 688 +G GA ++ G + +G F++P A+L+ G Y+ NG+ V + +SVLG G Sbjct: 762 HGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLE 821 Query: 689 VGYDFAVGNA-TVKPYLNLAALNEFSDGNKVRLGDESVNASIDGAAFRVGAGVQADITKN 747 VG + V+PY+ + L EF V + + G +G G+ A + + Sbjct: 822 VGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRG 881 Query: 748 MGAYASLDYTKGDDIENPLQGVVGINVTW 776 YAS +Y+KG + P G +W Sbjct: 882 HSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.7 bits (152), Expect = 2e-14 Identities = 31/172 (18%), Positives = 58/172 (33%), Gaps = 15/172 (8%) Query: 16 RRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLR 75 R+ ++D L ++ G+ ++ +IA+ AGV+ G I +F+DK+ L S + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 76 DAVLNRLHALPQGSAERRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQP-------ML 128 + L P L+ I+ + T V+ + + Sbjct: 72 ELELEYQAKFPGDPLS-VLREILIHVLEST-VTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 129 YRLQQVSSRRLLSNLVSEFRRE---LPRQQAQEAGYGLAALIDGL---WLRA 174 R + S + + + A + I GL WL A Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.4 bits (66), Expect = 0.020 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 233 FISGTGFATDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 291 +G ++D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 292 DVIVLGGGM 300 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.4 bits (123), Expect = 3e-09 Identities = 73/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%) Query: 33 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 89 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 90 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 149 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 150 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 209 G A G +S ++ P+ L FS F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 210 RDEAKGKLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 257 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 258 SGFSETAMTFIMMLVGLGM---VLGNVLSGRISGRYSPLRIAAVTDFIIVLALLMLFFFG 314 F A T + L G+ + +++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 315 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 368 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.4 bits (94), Expect = 4e-05 Identities = 40/264 (15%), Positives = 81/264 (30%), Gaps = 11/264 (4%) Query: 162 LNAKPKERAELLEELTGTEIYGKISAMVFEQHKSARTELEKLQAQASGVALLTPEQVQSL 221 A P E E + E + E S V + + A + + A Q+ Sbjct: 1029 APATPSETTETVAENSKQE-----SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN 1083 Query: 222 TASLQVLTDEEKQLLTAQQQEQQSLNWLTRLD-ELQQEASRRQQALQQALAEEEKAQPQL 280 + +E Q ++ +++ E QE + + + E QPQ Sbjct: 1084 EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA 1143 Query: 281 AALSLAQPARNLRPHWE---RIAEHSAALAHTRQQIEEVNTRLQSTMALRASIRHHAAKQ 337 P N++ A+ T +E+ T + + + + Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 338 SAELQQQQQSLNAWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHAEQKLN 397 A Q S ++ ++ R + + ++DR + T+ L+ Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPA-TTSSNDRSTVALCDLTSTNTNAVLS 1262 Query: 398 ALAAITLTLTADEVASALAQHAEQ 421 A + + V A++QH Q Sbjct: 1263 DARAKAQFVALN-VGKAVSQHISQ 1285 Score = 33.5 bits (76), Expect = 0.005 Identities = 27/139 (19%), Positives = 54/139 (38%), Gaps = 13/139 (9%) Query: 738 QQDVLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQ 797 Q DV + S + A+ D A A E T T E KQ + + Q Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPP-------APATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 798 TLVTQTAETLTQHQQHRPGGLSLTVTVEQIQQELAQTHQKLRENTTSQGEIRQQLKQDAD 857 TA+ ++ + V E+AQ+ + +E T++ + ++++ Sbjct: 1057 DATETTAQNREVAKEAKS-----NVKANTQTNEVAQSGSETKETQTTETKETATVEKEEK 1111 Query: 858 NRQQQQTLMQQIAQMTQQV 876 + + + Q++ ++T QV Sbjct: 1112 AKVETEK-TQEVPKVTSQV 1129
>PF06291#Lambda prophage Bor protein Length = 102 Score = 28.9 bits (64), Expect = 0.006 Identities = 12/37 (32%), Positives = 19/37 (51%) Query: 34 NMFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 70 N KK+LF ++ GCA+ T+ PT P++ Sbjct: 4 NKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.4 bits (66), Expect = 0.034 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 24/137 (17%) Query: 247 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 306 W+ L L+ G +A +LR R+ + + P++ G+I Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272 Query: 307 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSVFEDMGDWLRQHPQQHISINLE 365 AR+ +T + S +PL Q +S + ++ R D +R+ H + LE Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328 Query: 366 STVLTSEKIPQLLREMI 382 T L P ++R MI Sbjct: 329 QTAL----FPPMMRHMI 341
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1368 bits (3543), Expect = 0.0 Identities = 802/1033 (77%), Positives = 916/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTNYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT+YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.4 bits (105), Expect = 6e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 112 TYQAAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 171 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 172 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 230 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 231 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 280 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 281 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 312 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 7e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 61 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQAAYDS 119 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 120 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 179 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 180 RINLA 184 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 222 bits (567), Expect = 5e-76 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 38.5 bits (89), Expect = 9e-05 Identities = 40/251 (15%), Positives = 78/251 (31%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALST-LKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S+ ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 29.0 bits (65), Expect = 0.020 Identities = 11/43 (25%), Positives = 19/43 (44%) Query: 38 GQLAAVAIVTSDGNVYSAGDSDYRFALESISKVCTLALALEDV 80 G++ + + + G +A +D RF + S KV L V Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 5e-19 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%) Query: 16 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFT--GVLIDLDS 69 K ITG + GIG A L QG H+ A P+ +E++ S D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 189 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.013 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>PF09025#YopR Core Length = 143 Score = 28.1 bits (62), Expect = 0.020 Identities = 17/61 (27%), Positives = 25/61 (40%), Gaps = 8/61 (13%) Query: 126 EAVLIGQLECKSMVRMCAPLGSR--------LPLHASGAGKALLYPLAEEELMSIILQTG 177 + + +LE K+M+R PLG + L G L LA EL +I G Sbjct: 68 QGLEADRLELKAMLRAELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQVLIPLNG 127 Query: 178 L 178 + Sbjct: 128 M 128
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 56.3 bits (136), Expect = 1e-10 Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 32/163 (19%) Query: 4 DLIIKNGTVILENEARVVDIAVKDGKIAAIG-------QD-----LGDAKDVMDASGLVV 51 D +I N ++ DI +KDG+IAAIG Q +G +V+ G +V Sbjct: 69 DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 52 SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104 + G +D+H H P + A G+T M+ PA A+ Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177 Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146 I +AA ++ A G + L E+ G K Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 386 bits (994), Expect = e-138 Identities = 126/310 (40%), Positives = 176/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PHVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEATYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTEDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285 +GT +++ +R +EL + + GSMGPKV A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.030 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353 + ++ +L QAR R R + P E F +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 267 bits (684), Expect = 7e-93 Identities = 108/183 (59%), Positives = 132/183 (72%), Gaps = 1/183 (0%) Query: 51 MKTTHTSLPFAGHTLHFVEFDPASFREQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAIYA 110 M T+H LPFAGH LH V+FD +SFRE DLLWLPH+ +L+ AGRKRK EHLAGRIAA++A Sbjct: 1 MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA 60 Query: 111 LREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQPIGIDIEEIFSAQTAREL 170 LRE G + VP +G+ RQP+WP G++GSISHC TTALAV+SRQ IGIDIE+I S TA EL Sbjct: 61 LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL 120 Query: 171 TDNIITPAEHKRLADCGLAFPLALTLAFSAKESAFKA-SEIQTDADFLDYQIISRNKQQV 229 +II E + L L FPLALTLAFSAKES +KA S+ T F ++ S + Sbjct: 121 APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI 180 Query: 230 IIH 232 +H Sbjct: 181 SLH 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.3 bits (84), Expect = 2e-04 Identities = 82/394 (20%), Positives = 146/394 (37%), Gaps = 38/394 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSVRPGLLMLLSTLG---AFLAIGLFGLMP 309 A IG AA L + A+ +G +A + ++L + ++ + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403 + A + + +G+ + L LL L LRR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 62.7 bits (152), Expect = 2e-13 Identities = 60/280 (21%), Positives = 100/280 (35%), Gaps = 35/280 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQ 309 KD DA+ A PL +P V+ + + F SAM Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMH 283
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 443 bits (1141), Expect = e-161 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKAE-----------LREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 362 bits (930), Expect = e-130 Identities = 110/258 (42%), Positives = 150/258 (58%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATAMAFVEAGAKVTGFD---------------QAFTQEQYPFATE 49 GK ++TGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+A + ++ R+ E +D+LVN AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRHQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 28.8 bits (64), Expect = 0.017 Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 50 QGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISG--YMYNEKGENLSNTLIEK 107 + + + F+ YLGK+ ++ + G ++ + N+ G ++ N Sbjct: 21 ESVKPVSDFEL----NNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLN----- 71 Query: 108 EIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFADPF 145 Y+ + W+ E + ++G D + V F PF Sbjct: 72 RGYSEE-KGEWKEAEGKAYFVNGSTDGYLKVSFFG-PF 107
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 8e-24 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATTTP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.007 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 786 LLENAVKYAGAQAE----IGINAHVEGENLQLDVWDNGPGLPPGQEQT 829 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.4 bits (71), Expect = 0.003 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%) Query: 48 EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106 E+ + I+ ++ EG +V +L +L + +S +A R Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158 + L P + + T ++ E +L K A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 APAAAAPAAQPTLAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215 A + + + L + A +LE +N V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 216 LRKQYGEAFEKRHGIR 231 + + A E+ + Sbjct: 278 IESEILSAKEEYQLVT 293
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 28.4 bits (63), Expect = 0.025 Identities = 18/65 (27%), Positives = 26/65 (40%) Query: 255 AMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGN 314 AM N + + Y++G+ E A ++FQ LD + F LG Q G Sbjct: 26 AMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQ 85 Query: 315 IAEAI 319 AI Sbjct: 86 YDLAI 90
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 58.9 bits (142), Expect = 2e-11 Identities = 33/199 (16%), Positives = 68/199 (34%), Gaps = 8/199 (4%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158 E E+ Q QA+ + E A A ++ E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 159 AAK--KAAADAKKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAA--AAEARKKAATE 214 A+ K + +K E +A + + ++ A+ A + +K + E A +E ++ TE Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 215 AAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 274 E A E E+KA E + + K+ + +A ++ + + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 275 AAAAKAAAEKAAAAKAAAE 293 + A + A + ++ Sbjct: 1160 SQTNTTADTEQPAKETSSN 1178 Score = 56.6 bits (136), Expect = 1e-10 Identities = 30/236 (12%), Positives = 85/236 (36%), Gaps = 11/236 (4%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAV 180 + ++ A+EA + A+ A++ +E E + A + ++KA+ E K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 181 EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240 + ++ + ++++E + A AR+ T ++ +++ A E+ A + + Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 241 EKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADD 296 E+ + + + A ++ K + ++ + Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Score = 56.2 bits (135), Expect = 2e-10 Identities = 30/229 (13%), Positives = 72/229 (31%), Gaps = 4/229 (1%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAVEAQKK 185 +++ KQ + + A+ + + +E + A + A+ + VE Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDP-TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184 Query: 186 AEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA---EK 242 E E + + +++ + A ++ Sbjct: 1185 ESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244 Query: 243 AAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 291 + +D +A A+ A + A ++ ++ + Sbjct: 1245 STVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 55.8 bits (134), Expect = 2e-10 Identities = 32/265 (12%), Positives = 86/265 (32%), Gaps = 14/265 (5%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163 + E + ++ ++ Q K+ +K+ KA + + E ++ + K+ Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----EKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 164 AADA-KKKAEAEAAKAAVEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAE 222 ++ + +AE K+ ++ + A+ ++ + Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 223 AEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAA 282 + A + +++ K + + + + A + A + Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254 Query: 283 EKAAAAKAAAEADDIFGELSSGKNA 307 A + A A F L+ GK Sbjct: 1255 TNTNAVLSDARAKAQFVALNVGKAV 1279
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 46.1 bits (109), Expect = 9e-08 Identities = 35/146 (23%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVV--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPMWLQN 314 Y V+ GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 298 TPRFEDAFIDLLGGAGTSESPLGAILHTVGGTPGETVIEAKELTKKFGDFAATDHVNFAV 357 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 358 KRGEIFG----LLGPNGAGKSTTFKMMCGL 383 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.3 bits (65), Expect = 0.047 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 39 YVTGLVGPDGAGKTTLMRMLAGL 61 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.2 bits (151), Expect = 6e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 83 ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 142 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 143 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 197 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 198 AELNLQDSTLVAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 255 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 256 QPGRKVLLYTDGRPNKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 309 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 310 ----DADDALRQGMPVTVQ 324 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.7 bits (178), Expect = 7e-18 Identities = 33/214 (15%), Positives = 78/214 (36%), Gaps = 17/214 (7%) Query: 13 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 71 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 72 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACKNMIKLLTQDDTVNLSKFISREQL 131 IGE E + P + +RE+++ ++ + + + + F E + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120 Query: 132 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 191 A + + + + + +A L T + + G Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173 Query: 192 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 225 L W + + + ++ ++L+ Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.026 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 239 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFIGGWFI 296 +IGV+ + F + + P +M D H S GS+I T+ + + +IGG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 297 DHYSRVAVVR-ASALM--GALGIGLIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 352 D + V+ + L ++ S ++ + VL GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 353 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 382 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.3 bits (125), Expect = 1e-10 Identities = 14/81 (17%), Positives = 31/81 (38%) Query: 12 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIAALAGVPLGSMTYYFSGIDELLLEAFS 71 + + R+ I+ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 72 RFTEIMSRQYQAFFSDVSDAP 92 + + + P Sbjct: 65 LSESNIGELELEYQAKFPGDP 85
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 29.6 bits (66), Expect = 0.012 Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 9/72 (12%) Query: 100 QQRFNPDMVILADVNAQPSHISKPLMQRIE-----YFSSL-GRP--KAYSRYLRETIKPC 151 +QR N D++ ++ VN+Q KPL ++ YF+ L G+ Y L E +P Sbjct: 3 EQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPL 62 Query: 152 LER-LEHIRDSQ 162 L+ +++ R +Q Sbjct: 63 LDMVMQYTRGNQ 74
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 26.8 bits (59), Expect = 0.033 Identities = 21/80 (26%), Positives = 32/80 (40%), Gaps = 14/80 (17%) Query: 3 RLLLVVLALLLAALGWQTWR-------LADASQTISTQSDELQSKSQALAKSNSQLIS-- 53 R LLV+ L ++ + WQ W A + +T + + A +LIS Sbjct: 5 RNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVK 64 Query: 54 -----LSILTETNNREQARL 68 L+I T + EQA L Sbjct: 65 TDVLDLTINTRGGDVEQALL 84
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.7 bits (64), Expect = 0.049 Identities = 20/114 (17%), Positives = 34/114 (29%), Gaps = 11/114 (9%) Query: 50 PFAQTAVMGVQHAVAMFGATVLMPILMGLDPNLSIFMSGIGTLL--------FFFITGGR 101 PF + G + G ++P +M LS G + F +I G Sbjct: 257 PFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGIL 316 Query: 102 VPSYLGSSAAFVGVVIAATGFNGQGINPNISIALGGIIACGLVYTVIGLVVMKI 155 V +GV + F + + +V+ + GL K Sbjct: 317 VDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW---FMTIIIVFVLGGLSFTKT 367
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 30.6 bits (69), Expect = 0.030 Identities = 26/181 (14%), Positives = 59/181 (32%), Gaps = 22/181 (12%) Query: 451 HRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQA--AVLTHDVVEREPQDPGVV-R 507 A + A +++ + +E + + L ++ ++E E + + Sbjct: 49 EVARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINL 108 Query: 508 LK---RAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYS---PPLKDNWRGFAGF 561 LK ++ + N+ I+G E + DL P+ + F Sbjct: 109 LKDYFSSLTIDNMISKMISGVVT--EELKNYTSSLDDLVNGANLFIIDPMPNVL--FT-- 162 Query: 562 GYADGQFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWR 621 D S G G+ + + + R E +AE +F + + W + + Sbjct: 163 --RDPFASIGNGVT---INKMFTKVRQ--RETIFAEYIFKYHPVYKENVPIWLNRWEEAS 215 Query: 622 I 622 + Sbjct: 216 L 216
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.6 bits (56), Expect = 0.025 Identities = 6/15 (40%), Positives = 13/15 (86%) Query: 5 SQLLGISRSTIYEKM 19 + LLG++R+T+ +K+ Sbjct: 456 ADLLGLNRNTLRKKI 470
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 91.7 bits (227), Expect = 2e-24 Identities = 62/251 (24%), Positives = 119/251 (47%), Gaps = 15/251 (5%) Query: 3 RSVLVTGASKGIGRAIACQLAADGFNI-GVHYHRDAAGAQETLNAIVANGGNGRLLSFDV 61 + +TGA++GIG A+A LA+ G +I V Y+ + + ++ A + DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVS--SLKAEARHAEAFPADV 66 Query: 62 ANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSNDDWDAVIHTNLDSFYNVIQP 121 + E+ + G +V+ AG+ R +LS+++W+A N +N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 122 CIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCI 181 + + R+ G I+T+ S + Y+++KA + TK L +ELA+ I N + Sbjct: 127 -VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 182 APGLIDTGMIEM-------EESALKEAMSM----IPMKRMGQAEEVAGLASYLMSDIAGY 230 +PG +T M E +K ++ IP+K++ + ++A +L+S AG+ Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 231 VTRQVISINGG 241 +T + ++GG Sbjct: 246 ITMHNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 49.1 bits (117), Expect = 6e-08 Identities = 37/167 (22%), Positives = 77/167 (46%), Gaps = 12/167 (7%) Query: 246 YSDYASQQAKQDISTLGVATLLGVILLIVAVFRSLRPLLLCVISIGIGALAGTVATLLIF 305 + + + + TL A +L V L++ +++R L+ I++ + L GT A L F Sbjct: 329 TTPFVQLSIHEVVKTLFEAIML-VFLVMYLFLQNMRATLIPTIAVPV-VLLGTFAILAAF 386 Query: 306 G-ELHLMTLVMSMSVIGISADYTLYYL--TERMVHGNDVSPWQ----SLAKVRNALLLAL 358 G ++ +T+ + IG+ D + + ER++ + + P + S+++++ AL+ Sbjct: 387 GYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIA 446 Query: 359 LTTVAAYL-IMMLAPFPGI--RQMAIFAAIGLSASCLTVLFWHPWLC 402 + A ++ + G RQ +I ++ S L L P LC Sbjct: 447 MVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALC 493 Score = 37.9 bits (88), Expect = 2e-04 Identities = 34/199 (17%), Positives = 69/199 (34%), Gaps = 31/199 (15%) Query: 592 LVPVEGVKNSAALQEISSYYPCGIAWV---DRKNTFDELFALYRYVLTGLLLVALAVIAC 648 L + +K A L E+ ++P G+ + D +++ V T + L + Sbjct: 300 LDTAKAIK--AKLAELQPFFPQGMKVLYPYDTTPFVQL--SIHEVVKTLFEAIMLVFLVM 355 Query: 649 GAVARLGWRKGFISLVPSVLSLGCGLAVLAISGQAVNLFSLLALVLVLGIGI-------- 700 + R I + + L A+LA G ++N ++ +VL +G+ + Sbjct: 356 YLFLQ-NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 701 NYTLFFSNPRGTPLT-----------SLLAITLAMLTTLLTLGMLVFSATQAISSFGIVL 749 N + P +L+ I + + + + S F I + Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 750 VSGI----FTAFLLSPLAM 764 VS + A +L+P Sbjct: 475 VSAMALSVLVALILTPALC 493
>FLAGELLIN#Flagellin signature. Length = 507 Score = 31.2 bits (70), Expect = 0.008 Identities = 30/281 (10%), Positives = 68/281 (24%), Gaps = 1/281 (0%) Query: 38 LTGTGGIGFTIGSSKTSHDRREAGTTQSQSASTIGSTAGNVSITAGKQAHISGSDVIANR 97 L+ + +G++ + +S G S +V Sbjct: 137 LSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYD 196 Query: 98 DISITGDSVVVDPGHDRRTVDEKFEQKKSGLTVALSGTVGSAINNAVTSAQETKESSDSR 157 ++ + VD D + V + + + +A + +++ S Sbjct: 197 TYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKST 256 Query: 158 LKALQATKTALSGVQAGQAATMASATGDPNATGVSLSLTTQKSKSQQHSESDTVSGSTLN 217 +A A + ++ G+ G S + Sbjct: 257 AGTAEAKAIAGA-IKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADI 315 Query: 218 AGNNLSVVATGKNRGDNRGDIVIAGSQLKAGGNTSLDAANDILLSGAANTQKTTGRNSSS 277 +V A N V+ G + A L + A ++ + + Sbjct: 316 TAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGA 375 Query: 278 GGGVGVSIGAGKGAGISAFASVNAAKGREKGNGTEWTETTT 318 + AG + F A+ N + Sbjct: 376 EYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKS 416
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 132 bits (334), Expect = 1e-40 Identities = 67/72 (93%), Positives = 67/72 (93%) Query: 1 METAVAYYKDGVPYDDKGQVIITLLNDNPDGSGSGSGGGTGGSNSESSAAIHATAKWSTA 60 METAVAYYKDGVPYDDKGQVIITLLN PDGSGSG GGG GGS SESSAAIHATAKWSTA Sbjct: 1 METAVAYYKDGVPYDDKGQVIITLLNGTPDGSGSGGGGGKGGSKSESSAAIHATAKWSTA 60 Query: 61 QLKKTQAEQAAR 72 QLKKTQAEQAAR Sbjct: 61 QLKKTQAEQAAR 72
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 51.8 bits (124), Expect = 4e-11 Identities = 23/77 (29%), Positives = 34/77 (44%), Gaps = 2/77 (2%) Query: 48 AIQHNQIKFLFDSRGFPLAYITWAYLEADTEARLLRDPEFRLHPSEWNEDGRIWILDFCC 107 AIQ NQ L +P+AY +WA L + E + L D L +W R W +D+ Sbjct: 38 AIQANQYVLLTRD-DYPVAYCSWANLSLENEIKYLNDVT-SLVAEDWTSGDRKWFIDWIA 95 Query: 108 KPGFGRKVIDYLIQLQP 124 G + Y+ + P Sbjct: 96 PFGDNGALYKYMRKKFP 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 128 bits (324), Expect = 6e-35 Identities = 85/432 (19%), Positives = 163/432 (37%), Gaps = 59/432 (13%) Query: 27 WLIMLGSIVFITAFLMFIIVGTYSRRVNVSGEVTTWPRAVNIYSGVQGFVVRQFVHEGQL 86 + IM F+ + ++G +G++T R+ I V V EG+ Sbjct: 62 YFIMG----FLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGES 117 Query: 87 IKKGDPVYLIDISKST------------------RSGIVTDNHRRDIENQLVRVDKIISR 128 ++KGD + + + R I++ + + +L D+ + Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQ 177 Query: 129 LEESKKIT---------LDTLEKQRLQYTDAFRRSS-------DIIQRAEEGIKIMKNNM 172 +++ T + Q+ Q + I R E ++ K+ + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 173 ENYRNYQTKGLINKDQLTNQVALYYQQQNNLLSLSGQNEQNALQITTLESQIQTQAADFD 232 +++ + K I K + Q Y + N L Q EQ +I + + + Q F Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 233 NRIY----QMELQRYELQKELV-NTDVEGEIIIRALTDGKVDSLSV-TVGQMVNPGDNLL 286 N I Q L EL N + + +IRA KV L V T G +V + L+ Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLM 357 Query: 287 QVIPENIENYYLILWVPNDAVPYISAGDKVNIRYEAFPAEKFGQFSATVKTISRTPASTQ 346 ++PE+ + + V N + +I+ G I+ EAFP ++G VK I+ + + Sbjct: 358 VIVPED-DTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN--LDAIE 414 Query: 347 EMLTYKGAPQNTPGASVPWYKVIAMPEKQIIRYDEKNLPLENGMKAESTLFLEKRRIYQW 406 + G + + +I++ E + KN+PL +GM + + R + + Sbjct: 415 D---------QRLG--LVFNVIISIEENCLST-GNKNIPLSSGMAVTAEIKTGMRSVISY 462 Query: 407 MLSPFYDMKHSA 418 +LSP + + Sbjct: 463 LLSPLEESVTES 474
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 146 bits (370), Expect = 2e-49 Identities = 84/102 (82%), Positives = 88/102 (86%) Query: 1 MAQHEVITRGGDAFLLKLRESALSSGSMSEEQFFLLIGISSIHSDRVILAMKDYLVSGHS 60 MA HEVI+R G+AFLL +RES L GSMSE FFLLIGISSIHSDRVILAMKDYLV GHS Sbjct: 1 MAHHEVISRSGNAFLLNIRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHS 60 Query: 61 RKDVCEKYQMNNGYFSTTLGRLTRLNVLVARLAPYYTDSVSA 102 RK+VCEKYQMNNGYFSTTLGRL RLN L ARLAPYYTD SA Sbjct: 61 RKEVCEKYQMNNGYFSTTLGRLIRLNALAARLAPYYTDESSA 102
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 30.4 bits (68), Expect = 0.003 Identities = 39/160 (24%), Positives = 65/160 (40%), Gaps = 23/160 (14%) Query: 11 AALAGNHWHVMLPGGNMRFQGKIIAEACSLALSDRQMTVDMGQLSSNRFHAAGEYGDSVG 70 A L H H N+ F+GK+I AC++ + V+ G + +G G+ Sbjct: 15 AVLMSQHVHA---ADNLTFKGKLIIPACTV----QNAEVNWGDIEIQNLVQSG--GNQKD 65 Query: 71 FDIHLQGCSTVVSQRVGISFYGVSDIHEPELLSVDEENDASDGIAIALFNES----GELV 126 F + + ++ + +V I+ G + +L + + DG+ I L+N + G V Sbjct: 66 FTVDMNCPYSLGTMKVTITSNGQTG---NSILVPNTSTASGDGLLIYLYNSNNSGIGNAV 122 Query: 127 KLNQPPENWVHLTRGDMKLHMQARYKATHYPVTGGKANGQ 166 L +T G + AR K T Y G K N Q Sbjct: 123 TLGSQ------VTPGKITGTAPAR-KITLYAKLGYKGNMQ 155
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 963 bits (2490), Expect = 0.0 Identities = 546/861 (63%), Positives = 689/861 (80%), Gaps = 9/861 (1%) Query: 41 RMKFNILPLAFFIGIIVSPAR------AELYFNPRFLSDDPDAVADLSAFTQGQELPPGV 94 K + + + + A AELYFNPRFL+DDP AVADLS F GQELPPG Sbjct: 18 IRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGT 77 Query: 95 YRVDIYLNDTYISTRDVQFQMSQDGKQLAPCLSPEHMSAMGVNRYAVPGMERLPADTCTS 154 YRVDIYLN+ Y++TRDV F + + PCL+ +++MG+N +V GM L D C Sbjct: 78 YRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVP 137 Query: 155 LNSMIQGATFRFDVGQQRLYLTVPQLYMSNQARGYIAPEYWDNGITAALLNYDFSGNRVR 214 L SMI AT + DVGQQRL LT+PQ +MSN+ARGYI PE WD GI A LLNY+FSGN V+ Sbjct: 138 LTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQ 197 Query: 215 DSYGGTSDYAYLNLKTGLNIGSWRLRDNTSWSYSAGKGYS--QNNWQHINTWLERDIVSL 272 + GG S YAYLNL++GLNIG+WRLRDNT+WSY++ S +N WQHINTWLERDI+ L Sbjct: 198 NRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPL 257 Query: 273 RSRLTMGDSYTRGDIFDGVNFRGIQLASDDNMVPDSQRGYAPTIHGISRGTSRISIRQNG 332 RSRLT+GD YT+GDIFDG+NFRG QLASDDNM+PDSQRG+AP IHGI+RGT++++I+QNG Sbjct: 258 RSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNG 317 Query: 333 YEIYQSTLPPGPFEINDIYPAGSGGDLQVTLQEADGSVQRFNVPWSSVPVLQREGHLKYA 392 Y+IY ST+PPGPF INDIY AG+ GDLQVT++EADGS Q F VP+SSVP+LQREGH +Y+ Sbjct: 318 YDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYS 377 Query: 393 LSAGEFRSGGHQQDNPRFAEGTLKYGLPAGWTVYGGAWIAERYRAFNLGVGKNMGWLGAV 452 ++AGE+RSG QQ+ PRF + TL +GLPAGWT+YGG +A+RYRAFN G+GKNMG LGA+ Sbjct: 378 ITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 453 SLDATRANARLPDESRHDGQSYRFLYNKSLTETGTNIQLIGYRYSTRGYFSFADTAWKKM 512 S+D T+AN+ LPD+S+HDGQS RFLYNKSL E+GTNIQL+GYRYST GYF+FADT + +M Sbjct: 438 SVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRM 497 Query: 513 SGYSVLTQDGVIQIQPKYTDYYNLAYNKRGRVQVSISQQTGESSTLYLSGSHQSYWGTDR 572 +GY++ TQDGVIQ++PK+TDYYNLAYNKRG++Q++++QQ G +STLYLSGSHQ+YWGT Sbjct: 498 NGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSN 557 Query: 573 TDRQLNAGFNSSVNDISWSLNYSLSRNAWQHETDRILSFDVSIPFSHWMRSDSTSAWRNA 632 D Q AG N++ DI+W+L+YSL++NAWQ D++L+ +V+IPFSHW+RSDS S WR+A Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 633 SARYSQTLEAHGQAASTAGLYGTLLGDNNLGYSIQSGYTRGGYEGSSKTGYASLNYRGGY 692 SA YS + + +G+ + AG+YGTLL DNNL YS+Q+GY GG S TGYA+LNYRGGY Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 693 GNASAGYSHSGGYRQLYYGLSGGILAHANGLTLSQPLGDTLILVRAPGASDTRIENQTGV 752 GNA+ GYSHS +QLYYG+SGG+LAHANG+TL QPL DT++LV+APGA D ++ENQTGV Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 753 STDWRGYAVLPYATDYRENRVALDTNTLADNVDIENTVVSVVPTHGAVVRADYKTRVGVK 812 TDWRGYAVLPYAT+YRENRVALDTNTLADNVD++N V +VVPT GA+VRA++K RVG+K Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIK 797 Query: 813 VLMTLMRNGKAVPFGSVVTARNGGS-SIAGENGQVYLSGMPLSGQVSVKWGSQTTDQCTA 871 +LMTL N K +PFG++VT+ + S I +NGQVYLSGMPL+G+V VKWG + C A Sbjct: 798 LLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVA 857 Query: 872 DYKLPKESAGQILSHVTASCR 892 +Y+LP ES Q+L+ ++A CR Sbjct: 858 NYQLPPESQQQLLTQLSAECR 878
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 44.3 bits (104), Expect = 3e-06 Identities = 54/248 (21%), Positives = 93/248 (37%), Gaps = 25/248 (10%) Query: 501 AGTTTLNNGATFTLAGKTVNNDTLTIREGD-ALLQGGALTGNGRVEKS-GSGTLTVSNTT 558 A T + A+ G+ V N T I + A + G TG+ +S +G +T + Sbjct: 743 ATTMNVTGNASLYS-GRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDK 801 Query: 559 LTQKAVNLNEGTLTLNDSTVTTDIIAHRGTALKLTGSTVLNGAIDPTN--VTLTSGATWN 616 L+ KA+N + N + + ++ L + + N V LT + W+ Sbjct: 802 LSDKALN------SFNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWH 855 Query: 617 IPDNATVQSVVDDLSHAGQIHFTSARTGKFVPT--TLQVKNLNGQNGTISLRVRPDMAQN 674 + N+ V + H IH SA V TL V +L+G S D++ Sbjct: 856 LTGNSDVHQLDLANGH---IHLNSADNSNNVTKYNTLTVNSLSGNG---SFYYLTDLSNK 909 Query: 675 NADRLVIDGGRATGKTILNLVNAGNSGTGLATTGKGIQVVEAINGATTEEGAFVQGNMLQ 734 D++V+ ATG L + + + + +A + GN + Sbjct: 910 QGDKVVVT-KSATGNFTLQVAD-----KTGEPNHNELTLFDASKAQRDHLNVSLVGNTVD 963 Query: 735 AGAFNYTL 742 GA+ Y L Sbjct: 964 LGAWKYKL 971
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 28.4 bits (63), Expect = 0.043 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 137 GVNGDAVDPKSVTSWADL------WKPEYKGSLLLTDDAREVFQMALRKLGYSGNTTDPK 190 G GD DP T+W D + ++ +L D + FQM + +GN T P Sbjct: 42 GFGGDPCDP--CTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPT 99 Query: 191 EIEAAYN 197 + A N Sbjct: 100 TLTAREN 106
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 28.5 bits (63), Expect = 0.004 Identities = 11/36 (30%), Positives = 21/36 (58%) Query: 17 TSPGGTRHRITKLIVEGAIMKTLLPNVNTSEGCFEI 52 T G H++ K + AI + L+ NV++++ FE+ Sbjct: 91 TDSGAMSHKLEKADLLKAIQEQLIANVHSNDDYFEV 126
>INTIMIN#Intimin signature. Length = 939 Score = 30.8 bits (69), Expect = 0.006 Identities = 26/120 (21%), Positives = 44/120 (36%), Gaps = 20/120 (16%) Query: 134 KEVITRTVKVTNVGKPSVAEERSKITPVTAIKVTPTGTVEKGKTT-----------TLTV 182 ++ IT TVKV KP +E + T + + + T G ++ Sbjct: 675 QDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734 Query: 183 TVEPENATDK----TFRA-ISADPSKATI---SVKDMTITVTGVKDGKVSIPVISGNGQF 234 V K F ++ D I VK TV ++ G+V++ GNG++ Sbjct: 735 RVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVW-LQYGQVNLKASGGNGKY 793
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 42.7 bits (100), Expect = 6e-06 Identities = 55/377 (14%), Positives = 123/377 (32%), Gaps = 36/377 (9%) Query: 236 SGLIAMAKQFHNVTAEQIAYVAQLQRSGDETGALQAANEAATKGFDDQTRRLKENMGTLE 295 S ++ +E+ + + +L+ + + + + L+ L Sbjct: 95 SNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALA 154 Query: 296 TWADRTARAFKSMWDAVLDI-GRPDTAQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARA 354 +A + + + T + EA + + + + Sbjct: 155 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 214 Query: 355 RYWDDREKARLALEAARK-KAEQQTQQDKNAQQQSDTEASRLKYTEEAQRAYERLQTPLE 413 ++ K ++ + EA + + L+ + Sbjct: 215 TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 414 KYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHA 473 TA ++ + L+A+ L + A + + R D++ Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQ-SQVLNANRQSLR----------RDLDASRE 323 Query: 474 ALLTLQAELRTLEKHAGANEKISQQ-RRDL-------WKAESQFAVLEEAAQRRQLSAQE 525 A L+AE + LE+ +E Q RRDL + E++ LEE + + S Q Sbjct: 324 AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 383 Query: 526 KS--LLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAAIDAKSRGL 583 L A ++ + ++ L K+ E+LN +++ K ++++A Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKA------------ 431 Query: 584 TDRQAEREATEQRLKEQ 600 + QA+ EA + LKE+ Sbjct: 432 -ELQAKLEAEAKALKEK 447
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 148 bits (375), Expect = 8e-48 Identities = 66/200 (33%), Positives = 100/200 (50%), Gaps = 30/200 (15%) Query: 1 MRKLCAVILSAVVWLVAAGTPASAAEHQSTLSAGYLQTHTDMPGSDNLNGINVKYRYEFT 60 M+K+ + A V AGT +A ST++ GY Q+ + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DA-LGLITSFSYANAEDEQKTHYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGV 119 ++ LG+I SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDDRHSNTSLAWGAGVQFNPTESVTIDIAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+V +D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDAFIVGIGYRF 199 S +I G+GYRF Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 31.4 bits (71), Expect = 0.002 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 40 TKEHLLPHFL-EHLGNNHLDI------GVGTGFYLTHVPESSLISLMDLNEASLNAASTR 92 T EHL F+ HL + ++I G TGFY++ + S + D A++ Sbjct: 54 TLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKV 113 Query: 93 AGESKI 98 ++KI Sbjct: 114 ENQNKI 119
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.017 Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 46 LTLLGPSGCGKTTVLRLIAGLE-TVDSGRIMLDNED 80 + L G G GK+T++ + GL+ D+ + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 27.3 bits (60), Expect = 0.001 Identities = 10/24 (41%), Positives = 15/24 (62%) Query: 17 HGIFRDYELPHYSLITRIFHDGKQ 40 H + +Y HYS++ R FH+G Q Sbjct: 240 HILALNYAHWHYSIVARYFHNGGQ 263
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 28.6 bits (64), Expect = 0.007 Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 7/66 (10%) Query: 57 IMLAQHALLIAISSDLNAYGVVCEFDWN----DGNGQEGWPPMDGSEGIRITD---IDTS 109 + LA L I + D +G +F DG GQ G+ IT+ +D Sbjct: 22 VRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALILDHW 81 Query: 110 GIFDSD 115 GI +D Sbjct: 82 GIVKAD 87
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 26.6 bits (58), Expect = 0.030 Identities = 11/42 (26%), Positives = 22/42 (52%) Query: 13 VQAGMFSPELRTFTKGDAERLVSTTKKASDSAFWLEVEGNSM 54 V G +PE ++G+ + +S + + W++V GN+M Sbjct: 44 VDFGNINPEHVDNSRGEVTKNISISCPYKSGSLWIKVTGNTM 85
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 27.5 bits (61), Expect = 0.043 Identities = 17/77 (22%), Positives = 27/77 (35%), Gaps = 11/77 (14%) Query: 2 KNIAAQMVNFDREQM-----------RRIANNMPEQYDEKPQVQQVAQIINGVFSQLLAT 50 N+A ++ DR +++A+ E Y V V +IIN + Sbjct: 165 TNVARRIALMDRTSPEVVREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224 Query: 51 FPASLANRDQNELNEIR 67 SL D EI+ Sbjct: 225 IIESLEEEDPELAEEIK 241
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 509 bits (1312), Expect = 0.0 Identities = 241/388 (62%), Positives = 280/388 (72%), Gaps = 33/388 (8%) Query: 21 MKKLTVAISAVAASVLMAMSAQAAEIYNKDSNKLDLYGKVNAKHYFSSNDADDGDTTYAR 80 MK+ +A+ V ++L A +A AAEIYNKD NKLDLYGKV+ HYFS + + DGD TY R Sbjct: 1 MKRKVLAL--VIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMR 58 Query: 81 LGFKGETQINDQLTGFGQWEYEFKGNRAESQGSSKDKTRLAFAGLKFGDYGSIDYGRNYG 140 +GFKGETQINDQLTG+GQWEY + N E +G++ TRLAFAGLKFGDYGS DYGRNYG Sbjct: 59 VGFKGETQINDQLTGYGQWEYNVQANTTEGEGANS-WTRLAFAGLKFGDYGSFDYGRNYG 117 Query: 141 VAYDIGAWTDVLPEFGGDTWTQTDVFMTGRTTGVATYRNNDFFGLVDGLNFAAQYQGKND 200 V YD+ WTD+LPEFGGD++T D +MTGR GVATYRN DFFGLVDGLNFA QYQGKN+ Sbjct: 118 VLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177 Query: 201 R----------------TDVTEANGDGFGFSTTYEY-EGFGVGATYAKSDRTDGQVAYGK 243 D+ NGDGFG STTY+ GF GA Y SDRT+ QV G Sbjct: 178 SQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGG 237 Query: 244 SKFNASGKNAEVWAAGLKYDANNIYLATTYSETQNMTVFG------NNHIANKAQNFEAV 297 + A G A+ W AGLKYDANNIYLAT YSET+NMT +G + +ANK QNFE Sbjct: 238 T--IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVT 295 Query: 298 AQYQFDFGLRPSVAYLQSKGKDLGVH----GDRDLVKYVDVGATYYFNKNMSTFVDYKIN 353 AQYQFDFGLRP+V++L SKGKDL + D+DLVKY DVGATYYFNKN ST+VDYKIN Sbjct: 296 AQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 354 LID-DSKFTKTAGIDTDDIVAVGLVYQF 380 L+D D F K AGI TDDIVA+G+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>PF06291#Lambda prophage Bor protein Length = 102 Score = 189 bits (482), Expect = 2e-66 Identities = 102/102 (100%), Positives = 102/102 (100%) Query: 12 MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAA 71 MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAA Sbjct: 1 MQDNKMKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAA 60 Query: 72 KICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 113 KICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ Sbjct: 61 KICGGAENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 68.9 bits (168), Expect = 2e-17 Identities = 33/82 (40%), Positives = 46/82 (56%) Query: 41 ADEPRQLVTVYPRYPEYAAANYIKGLVEVKFDIGADGTVTRIVFLRSEPHNLFRDEVVKA 100 A PR L P+YP A A I+G V+VKFD+ DG V + L ++P N+F EV A Sbjct: 150 ASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNA 209 Query: 101 MAKWRFEKNRPCQGVKRQFIFT 122 M +WR+E +P G+ +F Sbjct: 210 MRRWRYEPGKPGSGIVVNILFK 231
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 31.2 bits (70), Expect = 0.010 Identities = 10/41 (24%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 310 TRDGLMFFSARGDEIPPPRSITFHIWTAYSPFTTWVQIVYD 350 R+ L+ F R DE P ++T W++ + ++ + + D Sbjct: 36 HREHLLEF-IRLDEPAPLNAMTLAQWSSPNVLSSLLAVYSD 75
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 30.7 bits (69), Expect = 0.002 Identities = 12/52 (23%), Positives = 24/52 (46%), Gaps = 1/52 (1%) Query: 2 TVISATAASSP-LPDTTGMLTLPAATPFTVMVIPLTDTVAFVLSADTARKLL 52 TVI+ +S+P + L A P T + L + +V+ D+ + ++ Sbjct: 250 TVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQYVIGVDSDQGMI 301
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.2 bits (96), Expect = 2e-05 Identities = 56/377 (14%), Positives = 125/377 (33%), Gaps = 36/377 (9%) Query: 236 SGLTAMARQFHNVTAEQIAYVAQLQRSGDESGALQAANEAATKGFDDQTRRLKENMGTLE 295 S R+ +E+ + + +L+ + + + + L+ L Sbjct: 95 SNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALA 154 Query: 296 TWADRTARAFKSMWDAVLDI-GRPDTAQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARA 354 +A + + + T + EA + + + + Sbjct: 155 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 214 Query: 355 RYWDDREKARLALEAARK-KAEQQSQQDKNAQQQSDTEASRLKYTEEAQKAYERLQTPLE 413 ++ K + ++ + EA + + + L+ + Sbjct: 215 TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 414 KYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHA 473 TA ++ + L+A+ L + A + + R D++ Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQ-SQVLNANRQSLR----------RDLDASRE 323 Query: 474 ALLTLQAELRTLEKHAGANEKISQQ-RRDL-------WKAESQFAVLEEAAQRRQLSAQE 525 A L+AE + LE+ +E Q RRDL + E++ LEE + + S Q Sbjct: 324 AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 383 Query: 526 KS--LLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAAIDAKSRGL 583 L A ++ + ++ L K+ E+LN +++ K ++++A Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKA------------ 431 Query: 584 TDRQAEREATEQRLKEQ 600 + QA+ EA + LKE+ Sbjct: 432 -ELQAKLEAEAKALKEK 447
>PF06291#Lambda prophage Bor protein Length = 102 Score = 27.7 bits (61), Expect = 0.012 Identities = 13/40 (32%), Positives = 19/40 (47%), Gaps = 5/40 (12%) Query: 122 MTGILFSLGASMVLGGVAQML-----APKARTPRTQTTDN 156 M +LFS +M++ G AQ P A TP+ T + Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHH 45
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 1e-05 Identities = 27/132 (20%), Positives = 56/132 (42%), Gaps = 15/132 (11%) Query: 123 SQSAAAAKKSETAAASSRNA--AKTSETNAGNSAKAAASSKTAAQNAATAAERSETNARA 180 S + A+ E A ++T+ET A NS + + + + Q+A + N Sbjct: 1012 SNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQ---NREV 1068 Query: 181 SEEASADSEEASRRN--AESAAENAGVATTKAREAAADATKAGQKKDEALSAATRAEKAA 238 ++EA ++ + ++ N A+S +E +E TK ++ A EK Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSE--------TKETQTTETKETATVEKEEKAKVETEKTQ 1120 Query: 239 DRAEVAAEVTAE 250 + +V ++V+ + Sbjct: 1121 EVPKVTSQVSPK 1132
>adhesinb#Adhesin B signature. Length = 310 Score = 297 bits (762), Expect = e-103 Identities = 85/262 (32%), Positives = 147/262 (56%), Gaps = 7/262 (2%) Query: 9 MLLGGLALTCSIAFQASATEKFKVITTFTIIADMAKNVAGDAAEVSSITKPGAEIHEYQP 68 +G A + + + + K V+ T +IIAD+ KN+AGD + SI G + HEY+P Sbjct: 13 AFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSIVPVGQDPHEYEP 72 Query: 69 TPGDIKRAQGAQLILANGMNLEL----WFQRFYQHLNGVPE---VIVSSGVTPVGITEGP 121 P D+K+ A LI NG+NLE WF + ++ VS GV + + Sbjct: 73 LPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVSEGVDVIYLEGQS 132 Query: 122 YEGKPNPHAWMSPDNALIYVDNIRDALIKYDPANAQTYQRNADTYKAKITQTLAPLRKQI 181 +GK +PHAW++ +N +IY NI L + DPAN +TY++N Y K++ +++ Sbjct: 133 EKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKF 192 Query: 182 TELPENQRWMVTSEGAFSYLARDLGLKELYLWPINADQQGTPQQVRKVVDIVKKNHIPAV 241 +P ++ +VTSEG F Y ++ + Y+W IN +++GTP Q++ +V+ ++K +P++ Sbjct: 193 NNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSL 252 Query: 242 FSESTISDKPARQVARETGAHY 263 F ES++ D+P + V+++T Sbjct: 253 FVESSVDDRPMKTVSKDTNIPI 274
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 42.7 bits (100), Expect = 5e-08 Identities = 26/101 (25%), Positives = 45/101 (44%), Gaps = 1/101 (0%) Query: 8 TRSIYRELGATLSYNMRLGNGMEIEPWLKAAVRKEFVDDNRVKVNSDGNFVNDLSGRRGI 67 S+ LG + + L G +++P++KA+V +EF V N + +L G R Sbjct: 811 GSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAH-RTELRGTRAE 869 Query: 68 YQAGIKASFSSTLSGHLGVGYSRGAGVESPWNAVVGVNWSF 108 G+ A+ S + YS+G + PW G +S+ Sbjct: 870 LGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 32.0 bits (72), Expect = 5e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 73 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 129 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 259 bits (663), Expect = 1e-89 Identities = 234/239 (97%), Positives = 236/239 (98%), Gaps = 1/239 (0%) Query: 18 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQA 77 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMV PADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 78 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQ-PKRDVKPVESR 136 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKV++ PKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 137 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 196 PASPFENTAPAR TSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 197 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 255 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 342 bits (880), Expect = e-118 Identities = 125/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 11 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 70 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 71 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFFDELATAPMMVQEKLLRVIE 130 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLF DE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 131 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 190 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 191 IMLMAEHFAIQMCREIKLPLFPGFTEHARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 250 I + HF Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 251 PLDDIIID---PFKRRPSEEAIAVSENTSLPTLPLD------------------LREFQM 289 + I + P E+A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 290 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 330 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.030 Identities = 7/43 (16%), Positives = 17/43 (39%) Query: 30 SGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A A++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.2 bits (133), Expect = 2e-12 Identities = 18/89 (20%), Positives = 37/89 (41%), Gaps = 16/89 (17%) Query: 12 VVAIGILLAGVVFFIW-WVSK--------GRFIQTTDDAYIGGNITTVASKVSGYISAIE 62 +VA I+ V+ FI + + G+ G + + + I Sbjct: 59 LVAYFIMGFLVIAFILSVLGQVEIVATANGKLT-------HSGRSKEIKPIENSIVKEII 111 Query: 63 VRDNQSVKKGDIILRLDDRDYRANVARLE 91 V++ +SV+KGD++L+L A+ + + Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQ 140
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 28.3 bits (63), Expect = 0.010 Identities = 16/51 (31%), Positives = 23/51 (45%), Gaps = 13/51 (25%) Query: 61 LNDMYAFIPGDNYYFIKS------SGYKFVND-------KWFTLKSINNIF 98 + M AFI D Y FIKS +G+ ND K ++ I ++F Sbjct: 4 VIKMEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVF 54
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 23.0 bits (49), Expect = 0.050 Identities = 13/39 (33%), Positives = 21/39 (53%), Gaps = 3/39 (7%) Query: 8 SLELYISGYLLWKFNLSAGIIFSPDFIRIILLILVLFLT 46 S+EL + + LW +LSA P +I IL+ + +F Sbjct: 443 SVELRQAPFALWIHDLSAQ---DPYYILPILMGVTMFFI 478
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 31.6 bits (71), Expect = 7e-04 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 16 LFTATLQAADVTITVNGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 L T+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPIETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 945 bits (2443), Expect = 0.0 Identities = 498/869 (57%), Positives = 652/869 (75%), Gaps = 10/869 (1%) Query: 15 QVLILPRFARLTFALGLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYR 74 + + F RL A A AE YFNPRFL++D DLS F G+E PPGTYR Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 75 VDIYLNDEFMASRDITFIADDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSADKHVPDN 134 VDIYLN+ +MA+RD+TF D+ ++PCL+ L S+G+ +++ + ++ + Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV-------SGMNLLAD 132 Query: 135 SACTPLQDRLADASSEFDVGQQHLSLSVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFN 194 AC PL + DA+++ DVGQQ L+L++PQ ++ ARGY+ P+LW+ GINAGLLNY+F+ Sbjct: 133 DACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFS 192 Query: 195 GNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTS 254 GNS N G S+YAYLNLQSG+NIG+WRLRDN+TWSYNS S+S NKWQHINT Sbjct: 193 GNS---VQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249 Query: 255 AERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTA 314 ERDIIPLRSRLT+GD YT GDIFD +NFRG ++ S + MLPDSQ GFAPVIHGIARGTA Sbjct: 250 LERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 315 QVSVKQNGYDVYQTTVPPGPFTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQ 374 QV++KQNGYD+Y +TVPPGPFTI+DI +A N GDLQVTIKEADGS Q VPYSSVP+LQ Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 375 RAGYTRYALAMGEYRSGNNLQSTPKFVQASLMHGLKGNWTPYGGMQIAEDYQAFNLGIGK 434 R G+TRY++ GEYRSGN Q P+F Q++L+HGL WT YGG Q+A+ Y+AFN GIGK Sbjct: 370 REGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGK 429 Query: 435 DLGLFGAFSFDITQANTTLADDTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNL 494 ++G GA S D+TQAN+TL DD++H GQSV+ +Y+KS ++GTNIQ+ GYRYST G++N Sbjct: 430 NMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNF 489 Query: 495 SDSAYSRMSGYTVKPPTGDTSEQTLFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASR 554 +D+ YSRM+GY ++ G + F DY+NL Y+KRG+ Q++++QQLG T + S S Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 555 QSYWNTSRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTD 614 Q+YW TS D+Q GLN F DI +L+YS + N WQ RD +LA +N+PFSHW+R+D Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSD 609 Query: 615 SQSAFHNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYS 674 S+S + +++ASYSMS+DL G MTNL+GVYGTLL DNNL+YSVQ G GG+ +SG++GY+ Sbjct: 610 SKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYA 669 Query: 675 SLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNV 734 +LNYRG YGN N+GYS S D Q+YYG+SGG++AHA+G+T GQPL DT+VLVKAPGA + Sbjct: 670 TLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDA 729 Query: 735 KIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARAT 794 K+ENQTG+ TDWRGYA+LP+ATEYRENRVAL+ N+LADNV+LD V V+PT GAI RA Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAE 789 Query: 795 FNVQIGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGK 854 F ++G K+LMTL + NK +PFGA+VT +++ IVA+NGQVYL+G+P +GK+QV WG+ Sbjct: 790 FKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGE 849 Query: 855 DKNSNCIVEYKLPEVSPGTLLNQQTAICR 883 ++N++C+ Y+LP S LL Q +A CR Sbjct: 850 EENAHCVANYQLPPESQQQLLTQLSAECR 878
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 54.5 bits (131), Expect = 3e-10 Identities = 41/192 (21%), Positives = 84/192 (43%), Gaps = 8/192 (4%) Query: 36 LSDIAHSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLS 95 L DIA+ F+ A + T + ++ + + ++ Q+ ++LL+ ++ V+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 96 FLSWS-FTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGL 154 F+ S F++L+++R A F ++ + R P R +A LI + A+ +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 155 PLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSI 214 +G ++ Y W I + +IT+ L+KLL + LMS+ Sbjct: 157 AIGGMIAHYIHWSY-LLLIPMITIITVPFLMKLLK------KEVRIKGHFDIKGIILMSV 209 Query: 215 YLLTVVVVTAHY 226 ++ ++ T Y Sbjct: 210 GIVFFMLFTTSY 221
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.7 bits (98), Expect = 3e-06 Identities = 42/239 (17%), Positives = 82/239 (34%), Gaps = 18/239 (7%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLI---GYAMTIALTIGVVFSLGF 63 R +L++ L +G G +P + L R S D+ G + + + + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADKFDKKRYMLMAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFAD 123 G L+D+F ++ +L+++ A + + + ++ + + + A A+ AD Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 124 NLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSINLPFWLAAICSAFPMLFIQIWVK 183 + + F G GP LG L+ S + PF+ AA + L + Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 184 RSEK---------IIATETGSVWSPKVLLQDKALLWFTCSGFLASFVSGAFASCISQYV 233 S K + W + A L F+ V A+ + Sbjct: 183 ESHKGERRPLRREALNPLASFRW--ARGMTVVAALMAV--FFIMQLVGQVPAALWVIFG 237 Score = 32.5 bits (74), Expect = 0.002 Identities = 21/155 (13%), Positives = 60/155 (38%), Gaps = 2/155 (1%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLIGYAMTIALTIGVVF-SLGFGI 65 +AL+A ++ + I+ ++ IG ++ + + ++ G Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 66 LADKFDKKRYMLMAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFADNL 125 +A + ++R +++ + A +G+I + + L+ + L+A + + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQV 328 Query: 126 SSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI 160 + ++ + ++ +GP L T + SI Sbjct: 329 DEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (251), Expect = 9e-28 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%) Query: 7 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 63 I +TGA G GE + R QG + A E+L+++ L A+ DVR+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 64 AAIEEMLASLPAEWSNIDILVNNAGLALGMEPAHKASIEDWETMIDTNNKGLVYMTRAVL 123 AAI+E+ A + E IDILVN AG+ L H S E+WE N+ G+ +R+V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 124 PGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 183 M++R G I+ +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 184 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 232 T+ + ++G + +T++ + L P D+++AV + VS H+ Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 233 INTL 236 ++ L Sbjct: 248 MHNL 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.7 bits (116), Expect = 3e-08 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 16/118 (13%) Query: 72 VGAFIFGKMGDRIGRKKVLFITITMMGICTTLIGVLPTYAQIGVFAPILLVTLRIIQGLG 131 +G ++GK+ D++G K++L I + + + V ++ + + A R IQG G Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMA-------RFIQGAG 116 Query: 132 AGAEISGAGTMLAEYAPKGKR----GIISSFVAMGTNCGTLSATAI-----WAFMFFI 180 A A + ++A Y PK R G+I S VAMG G I W+++ I Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.027 Identities = 54/312 (17%), Positives = 105/312 (33%), Gaps = 18/312 (5%) Query: 61 FAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYVFGFLAGMANSFLDAGTYPSL 120 G LSDRFGRRP +++ + + + + + Y+ +AG+ + A + Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYI 120 Query: 121 MEAFPRSPGTANI-LIKAFVSSGQFLLPLIISLLVWAELWFGWSFMIAAGIMFINALFLY 179 + + + A G P++ L+ F AA + +N L Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGC 178 Query: 180 RCTFPPHPGRHLPV---IKKTTSSTEHRCSIIDLASYSLYGYISMATFYLVSQWLAQYGQ 236 H G P+ +S + +A+ +I + + +G+ Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 237 FVAGMSYTM-SIKLLSIYTVGSLLCVFITAPLIRNTVRPTTLL--MLYTFISFIALLTVC 293 T I L + + SL IT P+ L+ M+ +I L Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 294 LHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERF--PYAKGKATGIYYSAGSIATFTIP 351 + +++ ++GG+ L M R +G+ G + S+ + P Sbjct: 299 RGWMAFPIMV------LLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGP 352 Query: 352 LITAHLSQRSIA 363 L+ + SI Sbjct: 353 LLFTAIYAASIT 364
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.008 Identities = 38/177 (21%), Positives = 75/177 (42%), Gaps = 9/177 (5%) Query: 14 ILAVLCIYFSYFLHGISVITLAQNMTSLAEKFSTDNAGIAYLISGIGLGRLISILFFGVI 73 IL LCI F ++ + L ++ +A F+ A ++ + L I +G + Sbjct: 15 ILIWLCIL--SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKL 72 Query: 74 SDKFGRRAVILMAVIMY----LLFFFGIPACPNLTLAYCLAVCVGIANSALDTGGYPALM 129 SD+ G + ++L +I+ ++ F G L +A + A AL Sbjct: 73 SDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY- 131 Query: 130 ECFPKASGSAVILVKAMVSFGQMFYPMLVSYMLLNNIWYGYGLIIPGILFVLITLML 186 + G A L+ ++V+ G+ P + M+ + I + Y L+IP I + + ++ Sbjct: 132 -IPKENRGKAFGLIGSIVAMGEGVGP-AIGGMIAHYIHWSYLLLIPMITIITVPFLM 186
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (301), Expect = 3e-39 Identities = 34/89 (38%), Positives = 55/89 (61%) Query: 4 TKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGR 63 K ++ + + L+K+D+ V+ F + L GE+V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPKTGEDIPITARRVVTFRPGQKLKSRVE 92 NP+TGE+I I A +V F+ G+ LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 104 bits (261), Expect = 1e-26 Identities = 80/373 (21%), Positives = 138/373 (36%), Gaps = 89/373 (23%) Query: 3 IGIDLGTTNSLAAVWRNGQSELIPNALGKFLTPSVVCVDEDG------MVLTGEAARDLQ 56 + IDLGT N+L V G ++ N PSVV + +D + G A Sbjct: 13 LSIDLGTANTLIYVKGQG---IVLN------EPSVVAIRQDRAGSPKSVAAVGHDA---- 59 Query: 57 LIKPQNCASNFKRMMGTS-------KTLKLG--GREFRAEELSSLILRQLKEDAENYLGE 107 K+M+G + + +K G F E++ ++Q+ ++ Sbjct: 60 -----------KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS---FMR 105 Query: 108 EVTEAVISVPAYFGDMQRKATKAAATMAGLNVERLINEPTAAALAYGLHNKDDEHQFLVF 167 ++ VP ++R+A + +A AG LI EP AAA+ GL + +V Sbjct: 106 PSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGS-MVV 164 Query: 168 DLGGGTFDVSILELFDNIMEVRAS-AGDNFLGGEDIVDILIDAYCSRRDLPENIEWREPT 226 D+GGGT +V+++ L + GD F E I++ + Y E T Sbjct: 165 DIGGGTTEVAVISLNGVVYSSSVRIGGDRF--DEAIINYVRRNY--------GSLIGEAT 214 Query: 227 LQRHLRIEAERVKRVLS--VRDEATFSVEIEGRRYYWHL-------TTEKFEFL---LQT 274 AER+K + + +E+ GR + + E E L L Sbjct: 215 --------AERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTG 266 Query: 275 FFERIHMPLER-------AIRDAKINFSQLDQVVLVGGTTRMPLIRKLVTRLFGRIPAMH 327 + + LE+ I + + VL GG + + +L+ G + Sbjct: 267 IVSAVMVALEQCPPELASDISERGM--------VLTGGGALLRNLDRLLMEETGIPVVVA 318 Query: 328 LNPDEVIAQGAAI 340 +P +A+G Sbjct: 319 EDPLTCVARGGGK 331
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 36.9 bits (85), Expect = 3e-05 Identities = 35/192 (18%), Positives = 55/192 (28%), Gaps = 58/192 (30%) Query: 8 PPRALLLV-DLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVI-----ASQD--- 58 P RA+LL+ D+QN F +L + C G V+ SQ+ Sbjct: 28 PNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 59 -------WHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLKQKAI 111 W P + + + P D + T W Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDDDLV-LTKW---------------------- 124 Query: 112 AAVFHKGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFTVLDAL 171 YSAF +T L + +R ++LI+ G+ T +A Sbjct: 125 -------------RYSAFK------RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAF 165 Query: 172 QLGYKVNVITDG 183 K + D Sbjct: 166 MEDIKAFFVGDA 177
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.7 bits (90), Expect = 4e-05 Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 3/130 (2%) Query: 88 ALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAATGAAFVPDMH--WLIFFRFLMGT 145 A M + IG+ G + D G +R ++I + FV LI RF+ G Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV-IGFVGHSFFSLLIMARFIQGA 115 Query: 146 GMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPMLSAAIGVVVIAFFSWRIMFLLG 205 G A + +IP RGK + + + AIG ++ + W + L+ Sbjct: 116 GAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP 175 Query: 206 GIGILLAWFL 215 I I+ FL Sbjct: 176 MITIITVPFL 185
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 28.9 bits (64), Expect = 0.021 Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 13/81 (16%) Query: 165 ETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKED-----------VLTDGIQTFPDR 213 E ++AL + N D K S S L + F ++V + + V ++ F + Sbjct: 57 EMSAALAQFRNRRDYEKKS-SNLSNSF-ERVLEDEALPKAKQILKLISVHGGALEDFLRQ 114 Query: 214 TDRVYLNPQDCSVINDEALNR 234 ++ +P D ++ E L R Sbjct: 115 ARSLFPDPSDLVLVLRELLRR 135
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.022 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.0 bits (67), Expect = 6e-04 Identities = 9/37 (24%), Positives = 17/37 (45%), Gaps = 5/37 (13%) Query: 4 LSWIIFGLIAGILAKWIMPG-----KDGGGFFMTILL 35 + I+ G I+G++ W+ K ++ ILL Sbjct: 163 AAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILL 199
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.018 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 175 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 229 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 495 bits (1277), Expect = e-179 Identities = 234/370 (63%), Positives = 271/370 (73%), Gaps = 31/370 (8%) Query: 1 MSAQAAEIYNKDSNKLDLYGKVNAKHYFSSNDADDGDTTYVRLGFKGETQINDQLTGFGQ 60 +A AAEIYNKD NKLDLYGKV+ HYFS + + DGD TY+R+GFKGETQINDQLTG+GQ Sbjct: 17 GAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVGFKGETQINDQLTGYGQ 76 Query: 61 WEYEFKGNRAESQGSSKDKTRLAFAGLKFGDYGSIDYGRNYGVAYDIGAWTDVLPEFGGD 120 WEY + N E +G++ TRLAFAGLKFGDYGS DYGRNYGV YD+ WTD+LPEFGGD Sbjct: 77 WEYNVQANTTEGEGANS-WTRLAFAGLKFGDYGSFDYGRNYGVLYDVEGWTDMLPEFGGD 135 Query: 121 TWTQTDVFMTGRTTGVATYRNNDFFGLVDGLNFAAQYQGKNDR----------------T 164 ++T D +MTGR GVATYRN DFFGLVDGLNFA QYQGKN+ Sbjct: 136 SYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQSADDVNIGTNNRNNGD 195 Query: 165 DVTEANGDGFGFSTTYEY-EGFGVGATYAKSDRTNDQVIYGNNSLNASGQNAEVWAAGLK 223 D+ NGDGFG STTY+ GF GA Y SDRTN+QV G A G A+ W AGLK Sbjct: 196 DIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGT--IAGGDKADAWTAGLK 253 Query: 224 YDANNIYLATTYSETQNMTVFG------NNHIANKAQNFEVVAQYQFDFGLRPSVAYLQS 277 YDANNIYLAT YSET+NMT +G + +ANK QNFEV AQYQFDFGLRP+V++L S Sbjct: 254 YDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSFLMS 313 Query: 278 KGKDLG----AWGDQDLVEYIDVGATYYFNKNMSTFVDYKINLIDKSD-FTKASGVATDD 332 KGKDL D+DLV+Y DVGATYYFNKN ST+VDYKINL+D D F K +G++TDD Sbjct: 314 KGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDDDPFYKDAGISTDD 373 Query: 333 IVAVGLVYQF 342 IVA+G+VYQF Sbjct: 374 IVALGMVYQF 383
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 120 bits (301), Expect = 6e-39 Identities = 102/103 (99%), Positives = 102/103 (99%) Query: 12 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTVARTQAEKFTL 71 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQT ARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 72 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 114 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 751 bits (1940), Expect = 0.0 Identities = 476/555 (85%), Positives = 512/555 (92%), Gaps = 5/555 (0%) Query: 3 ATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGA 62 +TA Q K LEWLNRLRANP+IPLIVAGSAAVA++VA++LWAK PDYRTLFSNLSDQDGGA Sbjct: 5 STATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGA 64 Query: 63 IVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 122 IV+QLTQMNIPYRF+ SGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ Sbjct: 65 IVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 124 Query: 123 FSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRA 182 FSEQVNYQRALEGEL+RTIET+GPVK ARVHLAMPKPSLFVREQKSPSASVTV L PGRA Sbjct: 125 FSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRA 184 Query: 183 LDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSGRDLNDAQLKYASDVEGRI 242 LDEGQISA+VHLVSSAVAGLPPGNVTLVDQ GHLLTQSNTSGRDLNDAQLK+A+DVE RI Sbjct: 185 LDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRI 244 Query: 243 QRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESHAALRSRQLNESEQSG 302 QRRIEAILSPIVGNGN+HAQVTAQLDFA+KEQTEE Y PNGD S A LRSRQLN SEQ G Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 303 SGYPGGVPGALSNQPAPANNAPISTPPANQNNRQQ--QASTTSNS---GPRSTQRNETSN 357 +GYPGGVPGALSNQPAP N API+TPP NQ N Q Q ST++NS GPRSTQRNETSN Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSN 364 Query: 358 YEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQMKQIEALTREAMGFSEK 417 YEVDRTIRHTKMNVGD++RLSVAVVVNYKTL DGKPLPL+ +QMKQIE LTREAMGFS+K Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK 424 Query: 418 RGDSLNVVNSPFNSSDESGGALPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLT 477 RGD+LNVVNSPF++ D +GG LPFWQQQ+FIDQLLAAGRWLLVL+VAW+LWRKAVRPQLT Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 478 RRAEAVKTVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 537 RR E K Q+QAQ R+E E+AVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR Sbjct: 485 RRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 544 Query: 538 VVALVIRQWINNDHE 552 VVALVIRQW++NDHE Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 341 bits (876), Expect = e-119 Identities = 117/329 (35%), Positives = 197/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE 60 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD 120 + + DY R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 371 bits (954), Expect = e-134 Identities = 221/228 (96%), Positives = 224/228 (98%) Query: 8 MSDNLPWKTWTPDDLAPPPAEFVPMAESEETIIEEVEPSLEQQLAQLQMQAHEQGYQAGI 67 MSDNLPWKTWTPDDLAPP AEFVP+ E EETIIEE EPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 68 AEGRQQGHEQGYQEGLAQGLEQGLAEAKAQQAPIHARMQQLVSEFQTTLDALDSVIASRL 127 AEGRQQGH+QGYQEGLAQGLEQGLAEAK+QQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 128 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 187 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 188 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 235 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 202 bits (515), Expect = 2e-70 Identities = 146/147 (99%), Positives = 147/147 (100%) Query: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 +TSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147 AALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 469 bits (1207), Expect = e-168 Identities = 365/375 (97%), Positives = 369/375 (98%) Query: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTAK 60 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPT K Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLVSDILSDAQQADLLIPVDETPPVINDEQSTLTPLTTAQTMTLAAVADKNTTKDEKA 120 GEPL+SDI+SDAQQA+LLIPVDETPPVINDEQST TPLTTAQTM LAAVADKNTTKDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPAEKPTLFTKLTSAQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLP EKPTLFTKLTS QLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTADASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTPLVAEAQSKAEVISTPSPVTA ASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMISPHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQM+SPHQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 Query: 361 LQGRVTGNSGVDIFA 375 LQGRVTGNSGVDIFA Sbjct: 361 LQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 385 bits (989), Expect = e-136 Identities = 85/324 (26%), Positives = 148/324 (45%), Gaps = 10/324 (3%) Query: 20 ILSQAEIDALLNGDS--EVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINERFA 77 +LSQ EID LL S + E +S I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 78 RHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 137 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 138 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 197 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 198 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 255 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 256 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKP---DRIIAHVD 312 + + L ++ +++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 313 GVPVLTSQYGTLNGQYALRIEHLI 336 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 209 bits (534), Expect = 2e-73 Identities = 124/137 (90%), Positives = 132/137 (96%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTSGKSATDAVFQQFGGGDVSGTLQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T+ KSA DAVFQQ GGGDVSG +QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 333 bits (856), Expect = e-119 Identities = 244/245 (99%), Positives = 244/245 (99%) Query: 1 MRRLFSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 MRRL SVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 202 bits (516), Expect = 6e-67 Identities = 256/261 (98%), Positives = 259/261 (99%) Query: 1 MMQVTSDQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 M+QVTS+QWLSWL+LYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPGSHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDP SHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGSEPLNSNAFLALTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG EPLNSNAFLALTKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEIFNLLADIISELPLI 261 EHLFSEIFNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.045 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 15/62 (24%) Query: 320 AKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRG 379 A+Y + PVLW Y+ R+ K + G+ VY +R +DG+E RG Sbjct: 166 ARYQVGPVLWGYVVRFIK---SDGDKLTLPYVY------------SRSQRDGSEAWKWRG 210 Query: 380 WD 381 WD Sbjct: 211 WD 212
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.8 bits (80), Expect = 2e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 46 AQKLAADDDVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFVQFPA-- 103 +KLA + + D+ +ILT + +L + Q + EE R+ E F A Sbjct: 219 GEKLAEEVNADIFMILTDV---NGAALYYGTEKEQWLREVKVEELRKYYEEG--HFKAGS 273 Query: 104 --EKIEAVCHAIAAHSFSAQIAPLTTEAKIVQ 133 K+ A I A IA L + ++ Sbjct: 274 MGPKVLAAIRFIEWGGERAIIAHLEKAVEALE 305
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 418 bits (1075), Expect = e-148 Identities = 199/388 (51%), Positives = 249/388 (64%), Gaps = 41/388 (10%) Query: 24 MKRKVLAMLVPALLVAGAANAAEIYNKNGNKVELYGKMVGERILTDRENGEKGDNSQDTS 83 MKRKVLA+++PALL AGAA+AAEIYNK+GNK++LYGK+ G +D ++ + GD + Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSD-DSSKDGD----QT 55 Query: 84 YARVGVKGETQINPELTGYGQFELDLEASNRHNPDQ---TRLAYAGLSYKDFGSFDYGRN 140 Y RVG KGETQIN +LTGYGQ+E +++A+ TRLA+AGL + D+GSFDYGRN Sbjct: 56 YMRVGFKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRN 115 Query: 141 VGVAYDAEAFTDMFVEWGGDSWAGTDLFMTNRTNGVATYRNTDFFGMVEGLNFALQYQGK 200 GV YD E +TDM E+GGDS+ D +MT R NGVATYRNTDFFG+V+GLNFALQYQGK Sbjct: 116 YGVLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGK 175 Query: 201 NEGTGNY----------------KANGDGHGLSATYTID-GFSFAGAYANSDRTDWQSGD 243 NE NGDG G+S TY I GFS AY SDRT+ Q Sbjct: 176 NESQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNA 235 Query: 244 GK----GERAEVWALSTKYDANNVYAAVMYGESHNM-------NSDDGDVVNKTQNFEAV 292 G G++A+ W KYDANN+Y A MY E+ NM DG V NKTQNFE Sbjct: 236 GGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVT 295 Query: 293 LQYQFDFGLRPSIGYSYSKALDVA----GYKDSDRLNYIEIGTWYYFNKNMNVYTAYQIN 348 QYQFDFGLRP++ + SK D+ D D + Y ++G YYFNKN + Y Y+IN Sbjct: 296 AQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 349 LLDKSD-YVLAHGLNTDDQLAVGIVYQF 375 LLD D + G++TDD +A+G+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 4e-05 Identities = 38/195 (19%), Positives = 74/195 (37%), Gaps = 34/195 (17%) Query: 261 TLSQIRSIAEYQKTIAGN-IEELENISRLTENILFLARADKNNVLVKLDALSLNKEVENL 319 L+ IR++ T A + L + R + L ++ V SL E+ + Sbjct: 178 ALNNIRALILEDPTKAREMLTSLSELMRYS-----LRYSNARQV-------SLADELTVV 225 Query: 320 LDYL--EYLSDEKEIRFKVECNQQIFADKI---LLQRMLSNLIVNAIRYSPEKSRIHITS 374 YL + E ++F+ + N I ++ L+Q ++ N I + I P+ +I + Sbjct: 226 DSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKG 285 Query: 375 FLDANGSLNIDIASPGTKINEPEKLFRRFWRGDNSRHSVGQGLGLSLVKA-IAELHGGSA 433 D NG++ +++ + G+ + K G GL V+ + L+G A Sbjct: 286 TKD-NGTVTLEVENTGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEA 330 Query: 434 TYHYLSKHNVFRITL 448 K + Sbjct: 331 QIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 9e-21 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 39 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 98 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 99 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 154 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 32.6 bits (74), Expect = 0.002 Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 8/86 (9%) Query: 2 IKKKGFTLLEVTIVL---GIGTLIAFMKFQDMRNDQEAVLADNVGTQIKQLGE--AVNRY 56 ++++GFTLLE+ ++L G+ + + F R+D A Q++ + + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 57 ---ISIRYDKISTLSSSNNQSSDPGP 79 +S+ D+ L +DP P Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAP 86
>PilS_PF08805#PilS N terminal Length = 185 Score = 73.4 bits (180), Expect = 8e-19 Identities = 47/179 (26%), Positives = 84/179 (46%), Gaps = 17/179 (9%) Query: 7 KRKSKKGFSLLELLLVLGIIAALVVAAFIVYPKVQASQRAQAESNNIATIQAGVKALYTS 66 K++ KG +L+E+LLV+G+I L +A+ +Y VQ++ ++ E NN+ T+ A +K+L Sbjct: 21 KKEQDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNEQNNVLTVIANMKSLKFQ 80 Query: 67 AS-SFTGLTNTVAVQAKIFPDNMLSGSGTAAKPINAFKGNVTLAATATGPSSATGSSFTI 125 + + T+ + P +M+ T A N + G+VT+ S+ SF + Sbjct: 81 GRYTDSNYIKTL-YAQGLLPSDMI-ADTTGASAKNPWGGSVTITT------SSDKYSFNV 132 Query: 126 TYDNVPAAECVKIATAAAGNFYITTVGTKVVKAAGGTLDVAATAAACTNATSNTLVFTS 184 NVP C+ + A + + T +AA + SNTL F++ Sbjct: 133 VEANVPQKNCMAMVNA--------LRSSSAISKINNTSTSTVSAATVCASDSNTLTFST 183
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.9 bits (59), Expect = 0.025 Identities = 9/23 (39%), Positives = 15/23 (65%) Query: 13 DKQMKKILLVAGAALALAGCGEK 35 D +MKK+L A A+ + GC ++ Sbjct: 3 DNKMKKMLFSAALAMLITGCAQQ 25
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 30.3 bits (68), Expect = 0.002 Identities = 13/53 (24%), Positives = 22/53 (41%), Gaps = 12/53 (22%) Query: 77 WFFTWKD------TGIQ-PGTAFVSSVVAGICFGVLMAAYHWWRKVVN--NLP 120 W W T I + ++A C G+ A+ WWRKV++ ++ Sbjct: 502 WDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGL---AWEWWRKVIDERDVK 551
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 25.1 bits (55), Expect = 0.034 Identities = 8/25 (32%), Positives = 14/25 (56%) Query: 35 SVVNERREEYYQEIGEKKAHKLKMK 59 +++N R Y IGE A ++K + Sbjct: 197 AIINYVRRNYGSLIGEATAERIKHE 221
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 51.6 bits (123), Expect = 1e-08 Identities = 22/70 (31%), Positives = 44/70 (62%) Query: 28 QQLRERLIQELNLTPQQLHEESNLIQAGLDSIRLMRWLHWFRKNGYRLTLRELYAAPTLA 87 + +R+++ + L TP+ + ++ +L+ GLDS+R+M + +R+ G +T EL PT+ Sbjct: 233 ENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIE 292 Query: 88 AWNQLMLSRS 97 W +L+ +RS Sbjct: 293 EWQKLLTTRS 302
>INTIMIN#Intimin signature. Length = 939 Score = 75.5 bits (185), Expect = 2e-17 Identities = 20/60 (33%), Positives = 29/60 (48%), Gaps = 3/60 (5%) Query: 181 QQIASTSQLIGSLLAEDMNSEQAANIARGWASSQASGVMTDWLSRFGTARITLGVDEDFS 240 QQ AS + S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224
>INTIMIN#Intimin signature. Length = 939 Score = 55.5 bits (133), Expect = 3e-10 Identities = 62/263 (23%), Positives = 91/263 (34%), Gaps = 20/263 (7%) Query: 175 IAVKAHVNDQFGNPVTHQPATFSAAPSSQMIISQNTVSTNTQGVAEVTMTPERNGSYTVK 234 I A V G + P +F+ S ++S N+ +TN G A VT+ ++ G V Sbjct: 578 ITYTATVKKN-GVAQANVPVSFNIV-SGTAVLSANSANTNGSGKATVTLKSDKPGQVVVS 635 Query: 235 ASLANGASLEKQLEAI---DEKLTLTSSPLIGVNAPKGATLTATLT---SANGTPVEGQV 288 A A S I K ++T A T T PV Q Sbjct: 636 AKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 289 INFSVTLEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTASFHNGVTIQTQTTVKVTGN 348 + F+ TL LS +T+++G A V LTS G V+A + V+ Sbjct: 696 VTFTTTL--GKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTT 753 Query: 349 PSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNL-IEGPTVYFALKSGSTTLTSLTA 407 + I T ++ G NL G + +S + + S Sbjct: 754 LTID------DGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIAS--- 804 Query: 408 VTDQNGIATTSVKGEITGSVTVS 430 V +G T KG T SV S Sbjct: 805 VDASSGQVTLKEKGTTTISVISS 827 Score = 52.8 bits (126), Expect = 2e-09 Identities = 46/170 (27%), Positives = 65/170 (38%), Gaps = 7/170 (4%) Query: 271 TLTATLTSANGTPVEGQVINFSVTLEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTAS 330 T TAT+ NG ++F++ A LS TN SG+A V L S+K G V+A Sbjct: 579 TYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK 637 Query: 331 FHNGV-TIQTQTTVKVTGNPSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGP 389 + + V + A + AD +T A D T V G + Sbjct: 638 TAEMTSALNANAVIFVDQ--TKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQ 694 Query: 390 TVYFALKSGSTTLTSLTAVTDQNGIATTSVKGEITGSVTVSAVTSAGGMQ 439 V F G + + T TD NG A ++ G VSA S + Sbjct: 695 EVTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVD 742 Score = 51.2 bits (122), Expect = 7e-09 Identities = 51/233 (21%), Positives = 89/233 (38%), Gaps = 16/233 (6%) Query: 13 AVTDADGKAKVTLKGTKAGAHTVTASMVGGKS--EQLVVNFTADTLTAQVNLNVTEDNFI 70 A T+ GKA VTLK K G V+A S V F T + + + + Sbjct: 612 ANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAV 671 Query: 71 ANNIGMTRLQATVTDGNGNPVEGIKVNFRGTSVTLSSTSVETDDQVFAEILVTSTEVGLK 130 AN V PV +V F T LS+++ +TD +A++ +TST G Sbjct: 672 ANGQDAITYTVKVMK-GDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730 Query: 131 TVSASLADKPTEVISRLLN----AKVDVNSATI----TSQEIPEGQVMVAQDIAVKAHVN 182 VSA ++D +V + + +D + I ++P + Q + N Sbjct: 731 LVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGN 790 Query: 183 DQFGNPVTHQPATFSAAPSSQMIISQNTVSTNTQGVAEVTMTPERNGSYTVKA 235 ++ + A S Q+ + + +T + V + + +YT+ Sbjct: 791 GKYTWRSANPAIASVDASSGQVTLKEKGTTTIS-----VISSDNQTATYTIAT 838 Score = 40.1 bits (93), Expect = 2e-05 Identities = 35/213 (16%), Positives = 63/213 (29%), Gaps = 18/213 (8%) Query: 4 NFTLSDGDKAVTDADGKAKVTLKGTKAGAHTVTASMVGGKSE--QLVVNFTADTLTAQVN 61 TD +G AKVTL T G V+A + + V F N Sbjct: 701 TLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGN 760 Query: 62 LNVTEDNFIANNIGMTRLQATVTDGNGN-PVEGIKVNFRGTSVTLSSTSVETDDQVFAEI 120 + + + + + G N G + S + SV+ Sbjct: 761 IEI-----VGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQ---- 811 Query: 121 LVTSTEVGLKTVSASLADKPTEVISRLLNAKVDVNSATITSQEIPEGQVMVAQDIAVKAH 180 VT E G T+S +D T + + + ++ + V ++ Sbjct: 812 -VTLKEKGTTTISVISSDNQT--ATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGG--- 865 Query: 181 VNDQFGNPVTHQPATFSAAPSSQMIISQNTVST 213 N + + + AA + S T+ + Sbjct: 866 KLPSSQNELENVFKAWGAANKYEYYKSSQTIIS 898
>INTIMIN#Intimin signature. Length = 939 Score = 27.7 bits (61), Expect = 0.022 Identities = 22/129 (17%), Positives = 46/129 (35%), Gaps = 6/129 (4%) Query: 11 KISAIDYSQNINGDYKATVTGGGEGIATLIPVLNGVHQAGLSTTIEFISAETRPMTGTVS 70 K+S + NG K T+T G + + ++ V + +EF G + Sbjct: 704 KLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFF-TTLTIDDGNIE 762 Query: 71 VNSANLPTASFPSQGFTGAYYQLNNDNFAPGKTAADYSFSSSASWVGVDATGKVTFKNDG 130 + + P+ L + G + ++ A ++G+VT K G Sbjct: 763 IVGTGV-KGKLPTVWLQYGQVNL---KASGGNGKYTWRSANPAIASVDASSGQVTLKEKG 818 Query: 131 DSNTVIITA 139 + T+ + + Sbjct: 819 -TTTISVIS 826
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 39/259 (15%), Positives = 96/259 (37%), Gaps = 18/259 (6%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ I+ ++ A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL----LIMARFIQGAGAAA 119 Query: 139 VGGEWGGAALLSVESAPKNKK-AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWG 197 + + K S V +G GVG + + I Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------------H 167 Query: 198 WRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHNQAAAKKRIPVIEALLRHPGAFLKIIA 257 W L ++ ++ ++ +++ + + + ++ +L + + Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 258 LRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRR 317 + + L +++ + + GL + + IG+L GG+ T+ F + + Sbjct: 228 VSVLSFL-IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV 286 Query: 318 VYITGALIGTLSAFPFFMA 336 ++ A IG++ FP M+ Sbjct: 287 HQLSTAEIGSVIIFPGTMS 305
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 33.3 bits (76), Expect = 0.002 Identities = 6/41 (14%), Positives = 16/41 (39%) Query: 303 LAADNRILYASGWFIDQNQGPYISHGGQNPNFSSCIALRPD 343 + +F+ ++ P + G NP+F + ++ Sbjct: 210 VGYKPHSKDPRDYFVPDSELPPLVQSGFNPSFIATVSHEKG 250
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 42.3 bits (99), Expect = 6e-06 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 956 DVRQMVATVRNTAPASGSER-LGDAAIRHSVRVCVEGALEQTEFDDNENLYVLGLDSIKS 1014 ++ A V+ T+ +G + IR + ++ E + D E+L GLDS++ Sbjct: 209 QLQNAPADVQKTSANTGKKNVFTCENIRKQIAELLQETPE--DITDQEDLLDRGLDSVRI 266 Query: 1015 IQIAAQLRHHGWTMSAVQVMECGTVNA 1041 + + Q R G ++ V++ E T+ Sbjct: 267 MTLVEQWRREGAEVTFVELAERPTIEE 293
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 51.2 bits (122), Expect = 1e-08 Identities = 32/167 (19%), Positives = 58/167 (34%), Gaps = 7/167 (4%) Query: 334 IPGNVLWIIGGEKGIGRMIGEALAQREGVRVVLSSRTGYHHEAVQQDAL------DVIHC 387 I G + +I G +GIG + LA +G + E V + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLAS-QGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 388 DVTQAEAVRACLATLLERYGRLDGVIFAADATTTLTLHQLSESALRDTLTVKERGTANVL 447 DV + A+ A + G +D ++ A +H LS+ T +V G N Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 448 HALAQRNLLDERLLLLFCNSLAAVNAEIGQTGYATASAYLDALAQQL 494 ++++ + ++ S A YA++ A + L Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 26.8 bits (59), Expect = 0.043 Identities = 12/30 (40%), Positives = 19/30 (63%) Query: 1 MIIDESAGEVVIGANTRICHGAVIQGPVVI 30 ++I+E G +VIGA+ RI AV G + + Sbjct: 263 VVINERTGTIVIGADVRISRVAVSYGTLTV 292
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 174 bits (444), Expect = 3e-54 Identities = 74/351 (21%), Positives = 143/351 (40%), Gaps = 40/351 (11%) Query: 1 MNILVTGGAGYIGSHTAIELLNAGHEIIVLDNFSNASYKCIEK---IKEITRRDFITITG 57 M LVTG AG+IG H + LL AGH+++ +DN N Y K ++ + + F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNL-NDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DAGCRKTLSAIFEKHAIDIVIHFAGFKSVSESKSEPLKYYQNNVGVTITLLQVMEEYRIK 117 D R+ ++ +F + V +V S P Y +N+ + +L+ +I+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 KFIFSSSATVYGEPEIIPIPETAKIGGTTNPYGTSKYFVEKILEDVSSTGKLDIICLRYF 177 +++SS++VYG +P + + Y +K E + S L LR+F Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 178 NPVGAHSSGKIGEAPSGIPNNLVPYLL--DVASGKRDKLFIYGNDYPTNDGTGVRDFIHV 235 G P G P ++ + + GK ++ N G RDF ++ Sbjct: 180 TVYG----------PWGRP-DMALFKFTKAMLEGKSIDVY--------NYGKMKRDFTYI 220 Query: 236 VDLAKGHLAAMNYL---------------SINSGYNIFNLGTGKGYSVLELITTFEKLTN 280 D+A+ + + + + + Y ++N+G +++ I E Sbjct: 221 DDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG 280 Query: 281 IKVNKSFIERRAGDVASCWADADKANSLLDWQAEQTLEQMLLDSWRWKKNY 331 I+ K+ + + GDV AD ++ + E T++ + + W +++ Sbjct: 281 IEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.8 bits (124), Expect = 4e-09 Identities = 48/369 (13%), Positives = 106/369 (28%), Gaps = 87/369 (23%) Query: 53 SYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPG-----ATKQAQQSPAGG-------R 100 S + R V ++ IA G+ + + A G + + + Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 101 RGMRA---DPLA---PVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDG--QLMALHF 152 G D L + A + L T ++ ++ +L Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 153 QEGQQVKAGDLLAEI------------DPSQFKVALAQAQGQLA-------KDKATLANA 193 Q V ++L Q ++ L + + + + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 194 RRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVA----------------- 236 + L + L +++ + Q+ E ++ ++ + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 237 --------------------------SAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSG 269 + + S I APV +V LK G +++ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 270 DTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSL 328 +T +V++ + +++ + DI + Q A + VEA+ T L + ++L Sbjct: 354 ETL-MVIVPEDDTLEVTALVQNKDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINL 410 Query: 329 DNQIDATTG 337 D D G Sbjct: 411 DAIEDQRLG 419
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 920 bits (2379), Expect = 0.0 Identities = 300/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLP-QLSDVSS 709 D F+ P I + T + F L DAL+ QL+ Q P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 915 bits (2367), Expect = 0.0 Identities = 288/1035 (27%), Positives = 503/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG------ALEDGTHRWQIQTNDELK 236 A+R+ L+ L ++ DV + N + G AL I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRARLPELQSTIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+A+L ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP +AVPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 AVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 + +A + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRGERS---ETAQQIIDRLRKKLAKEPGAN 641 + +V V GF+ G N+GM F++LKP ER+ +A+ +I R + +L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQANASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 696 + + I G ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QEDNGAEMNLIYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 816 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGN 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 80.7 bits (199), Expect = 2e-17 Identities = 76/448 (16%), Positives = 161/448 (35%), Gaps = 26/448 (5%) Query: 592 VDNVTGFTGGS-RVNSGMMFITLKPRGERSETAQQIIDRLRKKLAKEPGANLFLMAVQDI 650 +DN+ + S S + +T + + Q+ ++L+ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 651 RVGGRQANASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQEDNGAE-- 703 V ++ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 704 MNLIYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 759 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 760 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 817 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 818 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 874 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 875 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRH 934 L +P +G L F + + + G++L IG++ +AI++V+ Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 935 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQ 994 L P+EA ++ ++ + +P+ GG + + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 995 LLTLYTTPVVYLFFDRLRLRFSRKPKQA 1022 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKGG 510
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 126 bits (317), Expect = 9e-34 Identities = 98/435 (22%), Positives = 191/435 (43%), Gaps = 25/435 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQIGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAITTLM-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + LM L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGFSPLAIAGLVAVGVVALVLYLLHAQNNNRALFSLKL 257 G +L++VG+ L F+ + V V++ ++++ H + L Sbjct: 202 KGIILMSVGIVFFML---------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGFGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYT--WLSMASIIAL 445 +Y+ L + II + Sbjct: 428 LYSNLLLLFSGIIVI 442
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 34.0 bits (78), Expect = 0.001 Identities = 28/95 (29%), Positives = 36/95 (37%), Gaps = 20/95 (21%) Query: 164 RQTSWLIVALSTLLAALATF------PLARGLLAPVKRLVDGTHKLAAGDFTTRVAPTSE 217 RQ + L+ A L AL P L+A V+ V H LA + P S Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSF 131 Query: 218 DEL-----------GRLAEDFNQLASTLEKNQQMR 241 + L G L N+LA E+ QQMR Sbjct: 132 ERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 25.5 bits (55), Expect = 0.046 Identities = 13/38 (34%), Positives = 24/38 (63%), Gaps = 1/38 (2%) Query: 3 EGKVKKIAAISLISVFLMSGCAVHNDETSIGKFGLAYK 40 + +VKKI +S+++ ++ GC+ H ++ I K AYK Sbjct: 2 KNQVKKILGMSVVAAMVIVGCS-HAPKSGISKSNKAYK 38
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.5 bits (76), Expect = 0.001 Identities = 22/92 (23%), Positives = 35/92 (38%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSRE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQIQGVLRDLRFNQLILETAGVPQTVELA 246 A D ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 53/268 (19%), Positives = 89/268 (33%), Gaps = 17/268 (6%) Query: 29 LSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGAVLMYFAAQQ 88 L S G A A+ ++G+++DRF ++ + ++ AGA + Y Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAI--- 89 Query: 89 TTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIG-WIASGLACGF 147 A F +L + T A T ++A A + D+ R R G + G+ G Sbjct: 90 MATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG- 147 Query: 148 LPQMLGY-ADISPTNIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILL 206 P + G SP + P A + L + FL K + + L A Sbjct: 148 -PVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRW 205 Query: 207 RDKD------FLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFML 260 VFF + +P A + IF G + + Sbjct: 206 ARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM 265 Query: 261 ALPFFTKRFGIKKVLLLGLVTAAIRYGF 288 R G ++ L+LG++ Y Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYIL 293 Score = 34.0 bits (78), Expect = 0.001 Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 20/153 (13%) Query: 253 FSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGV 312 + L + RFG + VLL+ L AA+ Y +L++G ++ G+ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGI 108 Query: 313 SYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVN 372 + V D R G ++ C GFG + G LGG+M F+ P Sbjct: 109 TGATGAVAGAYIAD-ITDGDERARHFGFMS-ACFGFGMVAGPVLGGLMGG--FSPHAP-- 162 Query: 373 GLTFNWAGMWTFGAVMIAIIAVLFMIFFRESDN 405 + A + + + ES Sbjct: 163 ---------FFAAAALNGLNFLTGCFLLPESHK 186 Score = 28.6 bits (64), Expect = 0.048 Identities = 22/114 (19%), Positives = 43/114 (37%), Gaps = 4/114 (3%) Query: 7 LSFMMFVEWFIWGAWFVPLWLWL----SKSGFSAGEIGWSYACTAIAAILSPILVGSITD 62 ++ +M V + + VP LW+ + + A IG S A I L+ ++ Sbjct: 212 VAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 63 RFFSAQKVLAVLMFAGAVLMYFAAQQTTFAGFFPLLLAYSLTYMPTIALTNSIA 116 ++ L + M A A T FP+++ + + AL ++ Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLS 325
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.9 bits (62), Expect = 0.024 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 66 KMLLGALLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 106 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 28.9 bits (64), Expect = 0.037 Identities = 18/79 (22%), Positives = 34/79 (43%), Gaps = 8/79 (10%) Query: 93 NITLSNNQ---TSFTSGYSVTVTPAASNAKVNVSAGGGGSVMINGVATLSSA-----SSS 144 NI LS N+ T T + T++ S ++ + S G + + + + S+S Sbjct: 297 NIILSKNEDQSTQNTDSQTRTISKNTSTSRTHTSEVHGNAEVHASFFDIGGSVSAGFSNS 356 Query: 145 TRGSAAVQFLLCLLGGKSW 163 + A+ L L G ++W Sbjct: 357 NSSTVAIDHSLSLAGERTW 375
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 601 bits (1551), Expect = 0.0 Identities = 222/843 (26%), Positives = 361/843 (42%), Gaps = 93/843 (11%) Query: 7 LRMTPLASAI---VALLIGIEAYAAEETFDTHFMIGGMKDQQVSNIRL--EDNQPLPGPY 61 R+ + A +AE F+ F+ Q V+++ + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78 Query: 62 DIDIYVNKQWRGKYEIIVKDNPQET----CLSREMIKRLGINTDS-----FASGKQCLTF 112 +DIY+N + ++ E CL+R + +G+NT S + C+ Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 113 KQLIQGGSYTWDIGVFRLDFSVPQAWVEDLESGYVPPENWERGINAFYTSYYVSQYYSDY 172 +I + D+G RL+ ++PQA++ + GY+PPE W+ GINA +Y S Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 173 KASGNSKSTYVRFNSGLNLQGWQLHSDASFSKTNNNPGV-----WKSNTLYLERGFAQLL 227 + GNS Y+ SGLN+ W+L + ++S +++ W+ +LER L Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 228 GTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 287 L +GD YT DIFD + F G +L D MLP+S++ F P + GIA+ A VTI+QNG+ Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 288 VVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDF 347 +Y VPPGPF I D+ AG DL V++KEADGS + VPY++VP + + G ++Y Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 348 AAGRSHIEGASKQSD-FVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGWNT-RIGAIS 405 AG A ++ F Q+ +G T+YGG+ +A+ Y AF G G N +GA+S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 406 VDATKSHSIQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNK 465 VD T+++S + DGQS + YNK ++++ T L +RYS+ Y F D ++ Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 466 DNYRRDENDIYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVS--------WGDDV 513 ++ + + DYY + ++ ++Q L ++ WG Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 514 TTPRRQIYMSNSTT----------FDDQGVASNNTGLS-------GTVGSRDQFNYGVNL 556 + Q ++ + + + L+ D + + Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 557 SYQYQGNETTAGA---------------NLTWNAPVATVNG------------------- 582 S Y + G NL+++ G Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 583 -----SYSQSSAYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYR 637 YS S +Q VSGG++A + GV L L++T ++ APG KDA V Q Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 638 TTNRNGVVVYDGMTPYRENYLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKP 697 T+ G V T YREN + LD + +L P RGA+V F + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796 Query: 698 WFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVNVAIDKQQGLSCT 757 + L + +PL FG V + G+V Q+++ + V V +++ C Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 758 ITF 760 + Sbjct: 857 ANY 859
>PERTACTIN#Pertactin signature. Length = 922 Score = 27.0 bits (59), Expect = 0.024 Identities = 15/43 (34%), Positives = 26/43 (60%), Gaps = 2/43 (4%) Query: 40 VFAVIEKGGLLEV--KATGDFKIFVTDTGARPAAGDNLTLVTT 80 VFA + L V A+G +++V ++G+ PA+G+ + LV T Sbjct: 484 VFADLGLSDKLVVMRDASGQHRLWVRNSGSEPASGNTMLLVQT 526
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 2e-14 Identities = 22/113 (19%), Positives = 48/113 (42%), Gaps = 2/113 (1%) Query: 19 VMIVDDHPLMRRGVRQLLELDSGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGL 78 +++ DD +R + Q L +G++V + A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 79 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIR 131 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.0 bits (62), Expect = 0.007 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 34 KHIVLWLGLALACLGLAMVLWLLVL-QNVPV 63 + I+ +L + L C LAM+ W + L N PV Sbjct: 15 RRILFYLLMLLFCQQLAMIFWRIGLPDNAPV 45
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 30.5 bits (69), Expect = 0.013 Identities = 32/193 (16%), Positives = 59/193 (30%), Gaps = 37/193 (19%) Query: 268 GYGLTEFASTVCAKEADGLADVGSPL----PGREVKIVNDEVWLRAASMAEGYWRNGQRV 323 G+G+ S + A + L ++ + G + I+ E + A + + R+ Sbjct: 40 GHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIY---DQHRL 96 Query: 324 PLVNDEGWYATRDRGEMYNGKLTI-------VGRLDNLFFSGGEGIQPEEVERVIAAHPA 376 W + L I + RL G QP+ V V A Sbjct: 97 TTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRL---------GFQPDRVLTVWQQLRA 147 Query: 377 VLQVFIVPVADKEFGHRPVAVVEYDQQSVDLDEWVKDKLARFQQPVRWLTLPPELKNGGI 436 + V + + H A + + + +AR +Q L L N Sbjct: 148 MANVGEMTL----MSHFAEA---------EHPDGISGAMARIEQAAEGLECRRSLSNSAA 194 Query: 437 KISRQALK-EWVK 448 + +WV+ Sbjct: 195 TLWHPEAHFDWVR 207
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 32.1 bits (73), Expect = 5e-04 Identities = 13/74 (17%), Positives = 29/74 (39%), Gaps = 12/74 (16%) Query: 1 MIDWQDLHHSDLSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLEGENRHIL 52 M++ D++H+ LS ++ L LR F + D ++ ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNNN----TTYLF 56 Query: 53 GWHNGTLVAYARIL 66 G + T++ R + Sbjct: 57 GIKDNTVICSLRFI 70
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 250/251 (99%), Positives = 251/251 (100%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADSLYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD+LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 53.5 bits (128), Expect = 4e-10 Identities = 49/235 (20%), Positives = 86/235 (36%), Gaps = 27/235 (11%) Query: 47 WTDGQDRLQQGIMAGYGNEKSSTTSSLSGYKSKGAINGYSTGLYGTWQQNDGNDNGAYVD 106 R G +AGY T G+ + GY+T + D+G Y+D Sbjct: 683 VAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYI---------ADSGFYLD 733 Query: 107 TWIQYGWFNN--TVNGEKLAAESWKSR--GFTGSVEAGYTFKAGEFTGSQGSHYDWYIQP 162 ++ N V G A K R G S+EAG F W+++P Sbjct: 734 ATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTH---------ADGWFLEP 784 Query: 163 QSQITWMNVRASEHTEKNGTKVQLSGDGNIQSRLGVRTYLKGKSASDDNKAHQFEPFVEV 222 Q+++ + NG +V+ G ++ RLG+ GK + Q +P+++ Sbjct: 785 QAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEV---GKRI-ELAGGRQVQPYIKA 840 Query: 223 NWIHNTRSWG-VKMDNTALSQDGATNIAEVKTGVQGKLSDNLNVWGNVGVQAGDK 276 + + G V + A + AE+ G+ L +++ + G K Sbjct: 841 SVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPK 895
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 54.7 bits (131), Expect = 5e-09 Identities = 44/129 (34%), Positives = 59/129 (45%), Gaps = 12/129 (9%) Query: 2182 TLTVNGDYTGGGTLIINTVLGDDTSTTDKLIVTGNTSGDTGVVVNNVRGQGAQTADGIEI 2241 LTVN G G +N D +DKL+V + SG + V N G +A+ + + Sbjct: 472 VLTVN-TLAGSGLFRMNVFA--DLGLSDKLVVMQDASGQHRLWVRNS-GSEPASANTLLL 527 Query: 2242 VHVGGQSDGNFRLQN---RAVAGAWEYFLHKGNAGGTDGNWYLR-SELPPEPQPQPQPQP 2297 V S F L N + G + Y L A +G W L ++ PP P+P PQP P Sbjct: 528 VQTPLGSAATFTLANKDGKVDIGTYRYRL----AANGNGQWSLVGAKAPPAPKPAPQPGP 583 Query: 2298 QPQPQPQPQ 2306 QP PQPQ Sbjct: 584 QPPQPPQPQ 592
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 122 bits (308), Expect = 2e-32 Identities = 92/404 (22%), Positives = 167/404 (41%), Gaps = 17/404 (4%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197 E R A L V + GP +GG I W +L+ +PM I+ L L +E Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIILLTVVSVISLISLVIWES 257 ++ G+ L+ +G+ + ML F +S I +VSV+S + V Sbjct: 193 VRIKG-HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P ++++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLIS-PLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQG 376 G M ++I + G ++ ++ +V + S T F II+ G Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 377 FAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 + ++TI S L + S+ NF LS G ++ Sbjct: 362 LSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 6e-18 Identities = 62/413 (15%), Positives = 123/413 (29%), Gaps = 98/413 (23%) Query: 13 RRKYFALLAVVLFIAFSGAYAYWSMELKDMISTDDAYVTGNADPISAQVSGSVTVVNHKD 72 RR ++ F+ + + + +G + I + V + K+ Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 73 TNYVRQGDILVSLDKTDATIALNKA----------------------------------- 97 VR+GD+L+ L A K Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 98 -----------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDYN 137 K + Q + L + AE + + Y+ Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Query: 138 RRV----PLAKQGVISKEALEHTKDTLI----------SSKAALNAAIQAYKANKALVMN 183 R+ L + I+K A+ ++ + S + + I + K + Sbjct: 235 SRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE--YQLV 292 Query: 184 TPLNRQPQVIEAADATKE----------AWLALKRTDIKSPVTGYIAQRSVQ-VGETVSP 232 T L + + + T + + I++PV+ + Q V G V+ Sbjct: 293 TQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT 352 Query: 233 GQSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGN 291 ++LM +VP + V A + + + +GQ+ I + F G +G Sbjct: 353 AETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK-- 404 Query: 292 AFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 340 + + +V V +S++ L PL G+++TA I T Sbjct: 405 -VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 2e-17 Identities = 30/105 (28%), Positives = 51/105 (48%) Query: 960 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFE 1019 +IL+ADD R +L + L+ GYDV ++ ++ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1020 LTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLD 1064 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.3 bits (78), Expect = 8e-04 Identities = 11/33 (33%), Positives = 16/33 (48%) Query: 30 MVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFH 62 V L G G GK+TL+ + GL+ + H Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 156 bits (395), Expect = 4e-48 Identities = 95/255 (37%), Positives = 137/255 (53%), Gaps = 4/255 (1%) Query: 56 LTGKTALITGALQGIGEGIARTFARHGANLILLDISPE-IEKLADELCGRGHRCTAVVAD 114 + GK A ITGA QGIGE +ART A GA++ +D +PE +EK+ L A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 115 VRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMSDEDRDFHIDINIKGVWNVTK 174 VRD A++ R + + G IDILVN AGV R G +SDE+ + +N GV+N ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 175 AVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKAAIVGLTKSLAVEYAQSGIRVNA 234 +V M+ R+ G IV + S V AYA +KAA V TK L +E A+ IR N Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAG-VPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 235 ICPGYVRTPMAESIARQSNPEDP--ESVLTEMAKAIPMRRLADPLEVGELAAFLASDESS 292 + PG T M S+ N + + L IP+++LA P ++ + FL S ++ Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 293 YLTGTQNVIDGGSTL 307 ++T +DGG+TL Sbjct: 245 HITMHNLCVDGGATL 259
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 2e-09 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + F R P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 28.9 bits (64), Expect = 0.022 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 21/120 (17%) Query: 130 GNSLSSQEVLEGGESLILSE-----VAEPPVQMIDSLTTLFKTIKPVKRAFICLIKESEE 184 G++++SQE+L +S++ + E ++ +F+TI P+ + F +K E+ Sbjct: 217 GDTITSQELLAQAQSILNKNHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNREQ 276 Query: 185 A-QPNLLIGIEADGDIEEIIQAAGSVATDTLPGDEPIDICQVKKGEKGISHFITEHIAPF 243 A + N G+ + + ++I V +KKGEK F H+ F Sbjct: 277 AYRINKKSGLNEEINNTDLISEKYYV---------------LKKGEKPYDPFDRSHLKLF 321
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 115 bits (289), Expect = 3e-30 Identities = 81/371 (21%), Positives = 144/371 (38%), Gaps = 74/371 (19%) Query: 41 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 93 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 94 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 153 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 154 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 212 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 213 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG 272 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 273 --IPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 322 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 323 APLVKRTLLACRRALKDAGVE-ADEVLE--VVVVGGSTRVPLVRERVGEFFGRPPLTSID 379 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 380 PDKVVAIGAAI 390 P VA G Sbjct: 321 PLTCVARGGGK 331
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.032 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.2 bits (109), Expect = 5e-07 Identities = 33/165 (20%), Positives = 54/165 (32%), Gaps = 15/165 (9%) Query: 219 ETAAKNSQVAAAQSESAAAGSA--TSATGSATAAANSQKAAKTSETNAKSSQTAAKTSET 276 E +N V + A S + A +A A S+T +E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 277 NAKASETAAKNSQDA------------AAQSESAAAGSASAAASSASASANSQKAAKTSE 324 + + S+T KN QDA A+S A + A S S + +Q Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 325 TNAKASETAAANSAKASAASQTAAKASEDAAREYASQ-AAEPYKQ 368 + E A + K + ++ S + Q AEP ++ Sbjct: 1104 ATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE 1148 Score = 44.7 bits (105), Expect = 2e-06 Identities = 32/194 (16%), Positives = 65/194 (33%), Gaps = 11/194 (5%) Query: 111 PEALRRFEEMVEEAARNAEAASQSAAAAKKSETAAASSKNAAKTSETNAANSAQAAATSQ 170 + + E+ E + E ++ + K E + A E + + + + Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQT 1162 Query: 171 TASENSATAAKKSETNAKNSETAAKTSETNAK-----SSQTAAKTSETNAKASETAAKNS 225 + ++ AK++ +N + T + T T + T A T T S KN Sbjct: 1163 NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR 1222 Query: 226 QVAAAQSESAAAGSATSATGSATAAANSQKAAKTSETNAKSSQTAAKTS----ETNAKAS 281 + +S AT+++ + A ++ TNA S AK S Sbjct: 1223 HRRSVRSVPHNVEPATTSSNDRSTVA--LCDLTSTNTNAVLSDARAKAQFVALNVGKAVS 1280 Query: 282 ETAAKNSQDAAAQS 295 + ++ + Q Sbjct: 1281 QHISQLEMNNEGQY 1294
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 147 bits (372), Expect = 2e-47 Identities = 65/200 (32%), Positives = 101/200 (50%), Gaps = 30/200 (15%) Query: 1 MRKLCAVILSAVVWLVAAGTPASAAEHQSTLSAGYLQTHTDMPGSDDLKGINVKYRYEFT 60 M+K+ + A V AGT +A ST++ GY Q+ + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGLVTSFSYANAKDEQKTHYSDTRWHEDSVRNRWFSMMAGPSVRVNEWFSAYAMAGM 119 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + G+ Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDLAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>PF06291#Lambda prophage Bor protein Length = 102 Score = 28.1 bits (62), Expect = 0.012 Identities = 13/40 (32%), Positives = 19/40 (47%), Gaps = 5/40 (12%) Query: 122 MTGILFSLGASMVLGGVAQML-----APKARTPRTQTTDN 156 M +LFS +M++ G AQ P A TP+ T + Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHH 45
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 40.8 bits (95), Expect = 2e-05 Identities = 57/377 (15%), Positives = 125/377 (33%), Gaps = 36/377 (9%) Query: 236 SGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAATKGFDDQTRRLKENMGTLE 295 S R+ +E+ + + +L+ + + + + L+ L Sbjct: 95 SNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALA 154 Query: 296 TWADRTARAFKSMWDAVLDI-GRPDTAQEMLIKAEAAFKKADDIWNLRKDDYFVNDEARA 354 +A + + + T + EA + + + + Sbjct: 155 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIK 214 Query: 355 RYWDDREKARLALKAARK-KAEQQSQQDKNAQQQSDTEASRLKYTEEAQKAYKRLQTPLE 413 ++ K + ++ + EA + + K L+ + Sbjct: 215 TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 414 KYTARQEELNKALKDGKILQADYNTLMAAAKKDYEATLKKPKQSGVKVSAGDRQEDSAHA 473 TA ++ + L+A+ L + A + + R D++ Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQ-SQVLNANRQSLR----------RDLDASRE 323 Query: 474 ALLTLQAELRTLEKHAGANEKISQQ-RRDL-------WKAESQFAVLEEAAQRRQLSAQE 525 A L+AE + LE+ +E Q RRDL + E++ LEE + + S Q Sbjct: 324 AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQS 383 Query: 526 KS--LLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFAQQQRAKRAAIEAKSRGL 583 L A ++ + ++ L K+ E+LN +++ K ++++A Sbjct: 384 LRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKA------------ 431 Query: 584 TDRQAEREATEQRLKEQ 600 + QA+ EA + LKE+ Sbjct: 432 -ELQAKLEAEAKALKEK 447
>INTIMIN#Intimin signature. Length = 939 Score = 30.0 bits (67), Expect = 0.011 Identities = 32/202 (15%), Positives = 61/202 (30%), Gaps = 29/202 (14%) Query: 76 DWTATGQGQKSAGDTSFT----LAWMPGEQGQQALLAWFNEGDTRAYKIRFPNGTVDVFR 131 G G+ + S + + AL + A I + Sbjct: 611 SANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSAL-------NANAV-IFVDQTKASITE 662 Query: 132 GWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTAATGMTVTPASTSVVKGQSTTL 191 ++ IT TVKV +P ++ + T ++ + T TL Sbjct: 663 IKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTL 722 Query: 192 T---------------VAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKG--VAAGKV 234 T VA + + F ++ D + +G+ + + G+V Sbjct: 723 TSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQV 782 Query: 235 NIPVVSGNGEFAAVAEINVTAS 256 N+ GNG++ + AS Sbjct: 783 NLKASGGNGKYTWRSANPAIAS 804
>PF04183#IucA / IucC family Length = 580 Score = 29.5 bits (66), Expect = 0.007 Identities = 15/91 (16%), Positives = 33/91 (36%), Gaps = 17/91 (18%) Query: 76 DLHPGTLEFERHRLTRAQATAQELKN--AKESAEVVETAFCTFVLSRIAREISSILD--G 131 D G + + + QE+++ ++ SA+ + T + R IS ++ G Sbjct: 442 DFQ-GDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLG 500 Query: 132 IP------------LSVQRRFPELDNRHIDF 150 +P ++ P++ R F Sbjct: 501 VPERRFYQLLAAVLSDYMKKHPQMSERFALF 531
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 27.9 bits (62), Expect = 0.024 Identities = 10/45 (22%), Positives = 18/45 (40%), Gaps = 5/45 (11%) Query: 1 MKPRQRQAAILEYLQKQGKCSVEEL-----AQYFDTTGTTIRKDL 40 M QR I E + + +EL ++ T T+ +D+ Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDI 45
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 377 bits (969), Expect = e-128 Identities = 125/388 (32%), Positives = 194/388 (50%), Gaps = 33/388 (8%) Query: 174 IAALAAGALS----------NALLIEQLESQNMLPGEAAPFEAVKQTQMIGLSPGMTQLK 223 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 224 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 283 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 284 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLR 343 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 344 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 403 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 404 RLGLSRVVLSAGARNLLQHYNFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 458 + GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 459 FAFPEVTLPPPEVAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 501 + ++ V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 502 HNWAACARMLETDVANLHRLAKRLGLKD 529 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.019 Identities = 16/84 (19%), Positives = 36/84 (42%), Gaps = 12/84 (14%) Query: 292 IIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLVREQQEVKAGQKIATMGS 351 I+ATA+G++ ++G + IK ++ ++V+E + V+ G + + + Sbjct: 82 IVATANGKLTHSGRSK-------EIKP---IENSIV--KEIIVKEGESVRKGDVLLKLTA 129 Query: 352 TGTSSTRLHFEIRYKGKSVNPLRY 375 G + L + + RY Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRY 153
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.021 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.0 bits (83), Expect = 3e-04 Identities = 53/338 (15%), Positives = 123/338 (36%), Gaps = 34/338 (10%) Query: 93 LGSLVLGWISDHIGRQKIFTFSFMLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 151 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 152 GHTLLAEFSPRRHRGILLGAFSVVWT----VGYVLASIAGHHFISESPEAWRWLLASAAL 207 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 208 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLF-- 265 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 266 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 312 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 313 LNALLIVGALLGLVLTHLLAHRRFLLGSFLLLTATLVVMACLPSGSSLTLLLFVLFSTTI 372 + ++ G + ++ ++ G +L + ++ S F+L +T+ Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS-----VSFLTASFLLETTSW 349 Query: 373 SAVSNLVGILPAESFPTDIRSLGVGFATAMSRLGAAVS 410 +V +L SF + S V + GA +S Sbjct: 350 FMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMS 387
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (267), Expect = 1e-29 Identities = 73/257 (28%), Positives = 117/257 (45%), Gaps = 11/257 (4%) Query: 36 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEK-QGVEVD 94 M+ ++GK A +TG G+G+A A LA GA++ + + E K + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 95 FMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 154 D+ A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 155 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 214 F S +K M+ ++SG I+ + S + + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 215 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGAAVFLA 265 + N ++PG TD+ +L N Q + IP + D+ A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 266 SPASNYVNGHLLVVDGG 282 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.036 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLIMATYPPLWVMLCIQVA 107 G++++ + + G ++D+F R ++ ++ + IMAT P LWV+ ++ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 27.6 bits (61), Expect = 0.041 Identities = 17/74 (22%), Positives = 29/74 (39%), Gaps = 12/74 (16%) Query: 30 NASWSEVLNQYQRRTDLIPNLVASIKGYSSHEQEVLEAVTLARSQANRASSDLQKTPGDE 89 +AS ++ ++ Q D + L S GY + + N+ + P + Sbjct: 294 SASIEQIQSKIQELGDTLEELRDSFDGY------------INNAFVNQIHLNFVMPPQAQ 341 Query: 90 QKLQAWQQAQAQVT 103 Q+ QQ QAQ T Sbjct: 342 QQQGQGQQQQAQAT 355
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 80.7 bits (199), Expect = 1e-18 Identities = 44/142 (30%), Positives = 63/142 (44%), Gaps = 14/142 (9%) Query: 415 PEQKMEVTASLQVQTVRLDSMSLFDVGQARLKDGSTKVL---VDALVNIRAKPGWLILVA 471 +Q + L S LF+ +A LK L L N+ K G ++V Sbjct: 200 VAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDG-SVVVL 258 Query: 472 GYTDATGDEKSNQQLSLRRAEAVRNWMLQTSDIPATCFAVQGLGESQPAATNDTPQGR-- 529 GYTD G + NQ LS RRA++V ++ L + IPA + +G+GES P N + Sbjct: 259 GYTDRIGSDAYNQGLSERRAQSVVDY-LISKGIPADKISARGMGESNPVTGNTCDNVKQR 317 Query: 530 -------AVNRRVEISLVPRSD 544 A +RRVEI + D Sbjct: 318 AALIDCLAPDRRVEIEVKGIKD 339
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.0 bits (83), Expect = 7e-04 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 36/190 (18%) Query: 512 IMTLRQEGTDSTELQQQLRTHQGFAPLLALDVDARAVATVVADWTGIPLSSLLK------ 565 + + ++ +L +++ + P+L + + + A G L K Sbjct: 52 VTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGA-YDYLPKPFDLTE 110 Query: 566 --DEQSDLLSMEQSLENR----------VVGQSPALCAIAQRL-RAAKTGLTPENGPQGV 612 L+ + ++ +VG+S A+ I + L R +T LT Sbjct: 111 LIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT-------- 162 Query: 613 FLLTGPSGTGKTETALTLADTLFGGEKSLITINLSEYQEPHTVSQLKGSPPGYVGYGQGG 672 ++TG SGTGK A L D + IN++ S+L G + G Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKG 214 Query: 673 VLTEAVRKRP 682 T A + Sbjct: 215 AFTGAQTRST 224
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.010 Identities = 13/83 (15%), Positives = 35/83 (42%), Gaps = 9/83 (10%) Query: 33 ESKSVASAVFYKQIKILHLDFFSR---------SALNTDAEDTPLSTMVHVWQLKTREDF 83 + + V+Y+ K + LD S+ + + + ++D+ S ++ + K + + Sbjct: 161 INSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLEL 220 Query: 84 DKADYDTLFMQEEKTLEKDVLAK 106 + D F++E T + + Sbjct: 221 NNKSIDINFIKENLTEFQHAFSL 243
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 3e-06 Identities = 24/137 (17%), Positives = 54/137 (39%), Gaps = 24/137 (17%) Query: 360 LSIETRRLQLRIMMSHSLPLIRADISMIERVITNLLDNAVRH----TPPEGSIRLKVWQE 415 L + + + + R+ + + D+ + ++ L++N ++H P G I LK ++ Sbjct: 229 LQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD 288 Query: 416 DNRLHVEVADSGPGLTEDMRTHLFRRASVLCHEPSEEPRGGLGLLIVRRMLVLHGGD--- 472 + + +EV ++G + + + G GL VR L + G Sbjct: 289 NGTVTLEVENTGSLALK-----------------NTKESTGTGLQNVRERLQMLYGTEAQ 331 Query: 473 IRLTDSTTGACFRFFLP 489 I+L++ +P Sbjct: 332 IKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 1e-22 Identities = 35/129 (27%), Positives = 60/129 (46%) Query: 7 KILLMEDDYDIAALLRLNLQDEGYQIVHEADGARARLLLDKQTWDAVILDLMLPNVNGLE 66 IL+ +DD I +L L GY + ++ A + D V+ D+++P+ N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 ICRYIRQMTRYLPVIIISARTSETHRVLGLEMGADDYLPKPFSIPELIARIKALFRRQEA 126 + I++ LPV+++SA+ + + E GA DYLPKPF + ELI I + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 127 MGQNILLAG 135 + Sbjct: 125 RPSKLEDDS 133
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 317 bits (815), Expect = e-114 Identities = 161/170 (94%), Positives = 167/170 (98%) Query: 55 MNMNNPLEVLGHVSWLWASSPLHRNWPVSLFAINVLPAIRANQYALLTRDNYPVAYCSWA 114 MN+N PLE+LGHVSWLWASSPLHRNWPVSLFAINVLPAI+ANQY LLTRD+YPVAYCSWA Sbjct: 1 MNINKPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDDYPVAYCSWA 60 Query: 115 NLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIR 174 NLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIR Sbjct: 61 NLSLENEIKYLNDVTSLVAEDWTSGDRKWFIDWIAPFGDNGALYKYMRKKFPDELFRAIR 120 Query: 175 VDPKTHVGKVSEFHGGKIDKQLANKIFKQYYHELITEVKNKTDFNFSLTG 224 VDPKTHVGKVSEFHGGKIDKQLANKIFKQY+HELITEVK K+DFNFSLTG Sbjct: 121 VDPKTHVGKVSEFHGGKIDKQLANKIFKQYHHELITEVKRKSDFNFSLTG 170
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 1484 bits (3843), Expect = 0.0 Identities = 988/1024 (96%), Positives = 1001/1024 (97%) Query: 1 MPTITTAQIKSTLQSAKQSSANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQ 60 M TITTAQIKSTLQSAKQS+ANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQ Sbjct: 1 MTTITTAQIKSTLQSAKQSAANKLHSAGQSTKDALKKAAEQTRNAGNRLILLIPKDYKGQ 60 Query: 61 GSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQK 120 GSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQK Sbjct: 61 GSSLNDLVRTADELGIEVQYDEKNGTAITKQVFGTAEKLIGLTERGVTIFAPQLDKLLQK 120 Query: 121 YQKAGNKLGGSAENIGDNLGKAGSVLSTFQNFLGTALSSMKIDELIKRQKSGSNVSSSEL 180 YQKAGN LGG AENIGDNLGKAG +LSTFQNFLGTALSSMKIDELIK+QKSG NVSSSEL Sbjct: 121 YQKAGNILGGGAENIGDNLGKAGGILSTFQNFLGTALSSMKIDELIKKQKSGGNVSSSEL 180 Query: 181 AKASIELINQLVDTAASINNNVNSFSQQLNKLGSVLSNTKHLTGVGNKLQNLPNLDNIGA 240 AKASIELINQLVDT AS+NNNVNSFSQQLN LGSVLSNTKHL GVGNKLQNLPNLDNIGA Sbjct: 181 AKASIELINQLVDTVASLNNNVNSFSQQLNTLGSVLSNTKHLNGVGNKLQNLPNLDNIGA 240 Query: 241 GLDTVSGILSAISASFILSNADADTGTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGL 300 GLDTVSGILSAISASFILSNADADT TKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGL Sbjct: 241 GLDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGL 300 Query: 301 STSAAAAGLIASVVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKE 360 STSAAAAGLIAS VTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKE Sbjct: 301 STSAAAAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLGYDGDSLLAAFHKE 360 Query: 361 TGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEH 420 TGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEH Sbjct: 361 TGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILEASKQAMFEH 420 Query: 421 VASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHW 480 VASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHW Sbjct: 421 VASKMADVIAEWEKKHGKNYFENGYDARHAAFLEDNFKILSQYNKEYSVERSVLITQQHW 480 Query: 481 DTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKPDEFQKQVFDPLKGNIDLSDSKSS 540 DTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKK DEFQKQVFDPLKGNIDLSDSKSS Sbjct: 481 DTLIGELAGVTRNGDKTLSGKSYIDYYEEGKRLEKKXDEFQKQVFDPLKGNIDLSDSKSS 540 Query: 541 TLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGSVYDYSNLIQHA 600 TLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKG+VYDYSNLIQHA Sbjct: 541 TLLKFVTPLLTPGEEIRERRQSGKYEYITELLVKGVDKWTVKGVQDKGAVYDYSNLIQHA 600 Query: 601 SVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATE 660 SVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATE Sbjct: 601 SVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATE 660 Query: 661 AGNYTVTRVLGGDVKILQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVE 720 AGNYTVTRVLGGDVK+LQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVE Sbjct: 661 AGNYTVTRVLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVE 720 Query: 721 ELIGTTRADKFFGSKFTDIFHGADGDDHIEGNDGNDRLYGDKGNDTLRGGNGDDQLYGGD 780 ELIGTTRADKFFGSKFTDIFHGADGDD IEGNDGNDRLYGDKGNDTL GGNGDDQLYGGD Sbjct: 721 ELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGD 780 Query: 781 GNDKLIGGTGNNYLNGGDGDDELQVQGNSLAKNVLSGGKGNDKLYGSEGADLLDGGEGND 840 GNDKLIG GNNYLNGGDGDDE QVQGNSLAKNVL GGKGNDKLYGSEGADLLDGGEG+D Sbjct: 781 GNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDD 840 Query: 841 LLKGGYGNDIYRYLSGYGHHIIDDDGGKDDKLSLADIDFRDVAFRREGNDLIMYKAEGNV 900 LLKGGYGNDIYRYLSGYGHHIIDDDGGK+DKLSLADIDFRDVAF+REGNDLIMYK EGNV Sbjct: 841 LLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKGEGNV 900 Query: 901 LSIGHKNGITFRNWFEKESGDISNHQIEQIFDKDGRVITPDSLKKALEYQQSNNKASYVY 960 LSIGHKNGITFRNWFEKESGDISNH+IEQIFDK GR+ITPDSLKKALEYQQ NNKASYVY Sbjct: 901 LSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKKALEYQQRNNKASYVY 960 Query: 961 GNDALAYGSQDNLNPLINEISKIISAAGNFDVKEERAAASLLQLSGNASDFSYGRNSITL 1020 GNDALAYGSQ +LNPLINEISKIISAAG+FDVKEER AASLLQLSGNASDFSYGRNSITL Sbjct: 961 GNDALAYGSQGDLNPLINEISKIISAAGSFDVKEERTAASLLQLSGNASDFSYGRNSITL 1020 Query: 1021 TASA 1024 T SA Sbjct: 1021 TTSA 1024
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 599 bits (1547), Expect = 0.0 Identities = 463/478 (96%), Positives = 468/478 (97%) Query: 1 MKTWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLV 60 MKTWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLV Sbjct: 1 MKTWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLV 60 Query: 61 AYFIMGFLVIAVILSVLGQVEIVATANGKLTLSGRSKEIKPIENSIVKEIIVKEGESVRK 120 AYFIMGFLVIA ILSVLGQVEIVATANGKLT SGRSKEIKPIENSIVKEIIVKEGESVRK Sbjct: 61 AYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRK 120 Query: 121 GDVLLKLTALGAEADTLKTQSSLLQTRLEQTRYQILSRSIELNKLPELKLPDEPYFQNVS 180 GDVLLKLTALGAEADTLKTQSSLLQ RLEQTRYQILSRSIELNKLPELKLPDEPYFQNVS Sbjct: 121 GDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVS 180 Query: 181 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTILARINRYENLSRVEKSRLDDF 240 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT+LARINRYENLSRVEKSRLDDF Sbjct: 181 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Query: 241 RSLLHKQAIAKHAVLEQENKYVEAANELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 SLLHKQAIAKHAVLEQENKYVEA NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 301 LDKLRQTTDNIELLTLELEKNEERQQASVIRAPVSGKVQQLKVHTEGGVVTTAETLMVIV 360 LDKLRQTTDNI LLTLEL KNEERQQASVIRAPVS KVQQLKVHTEGGVVTTAETLMVIV Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV 360 Query: 361 PEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQKLGL 420 PEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQ+LGL Sbjct: 361 PEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGL 420 Query: 421 VFNVIVSVEENDLSTGNKHIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLHER 478 VFNVI+S+EEN LSTGNK+IPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESL ER Sbjct: 421 VFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478
>PF03627#PapG Length = 336 Score = 603 bits (1555), Expect = 0.0 Identities = 333/336 (99%), Positives = 335/336 (99%) Query: 1 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT 60 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT Sbjct: 1 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT 60 Query: 61 WNQCNGPEFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF 120 WNQCNGP FADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF Sbjct: 61 WNQCNGPGFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF 120 Query: 121 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFNDIIFKVALPADLPLGDYSVTIPYTSGIQ 180 FLKGYKWDERAFDAGNLCQKPGETTRLTEKF+DIIFKVALPADLPLGDYSVTIPYTSG+Q Sbjct: 121 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSVTIPYTSGMQ 180 Query: 181 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY 240 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY Sbjct: 181 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY 240 Query: 241 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY 300 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY Sbjct: 241 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY 300 Query: 301 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP 336 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP Sbjct: 301 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP 336
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 267 bits (683), Expect = 5e-95 Identities = 155/167 (92%), Positives = 156/167 (93%), Gaps = 1/167 (0%) Query: 11 MARLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGE 70 M RLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGE Sbjct: 1 MIRLSLFISLLLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNINPEHVDNSRGE 60 Query: 71 VTKTISISCTYKSGSPWIKVTGNAMA-GQTNVLATNIANFGIALYQGKGMSTPLTLGNGS 129 VTK ISISC YKSGS WIKVTGN M GQ NVLATNI +FGIALYQGKGMSTPLTLGNGS Sbjct: 61 VTKNISISCPYKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGNGS 120 Query: 130 GNGYRVTAGLDTARSTFTFTSVPFRNGSRTLNGGDFRTTASMSMIYN 176 GNGYRVTAGLDTARSTFTFTSVPFRNGS LNGGDFRTTASMSMIYN Sbjct: 121 GNGYRVTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMIYN 167
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 306 bits (784), Expect = e-110 Identities = 128/173 (73%), Positives = 145/173 (83%) Query: 7 MKKIRGLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTVTKAEVDWGNVEIQTLSQNG 66 MKKIRGLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTV AEV+WG++EIQ L Q+G Sbjct: 1 MKKIRGLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTVQNAEVNWGDIEIQNLVQSG 60 Query: 67 NHEKEFTVNMQCPYHLGTMKVTITATNTYNNAILVQNTSNTSSDGVLVYLYNSNAGNIGT 126 ++K+FTV+M CPY LGTMKVTIT+ N+ILV NTS S DG+L+YLYNSN IG Sbjct: 61 GNQKDFTVDMNCPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGN 120 Query: 127 AITLGTPFTPGKITGNNADRTISLHAKLGYKGNMQSLKAGDFSATATLVASYS 179 A+TLG+ TPGKITG R I+L+AKLGYKGNMQSL+AG FSATATLVASYS Sbjct: 121 AVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASYS 173
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 742 bits (1917), Expect = 0.0 Identities = 243/882 (27%), Positives = 362/882 (41%), Gaps = 67/882 (7%) Query: 2 MRGMKDRI-PFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLP 60 + K R+ F V + +++ + FN L + D +RF + P Sbjct: 16 LHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPP 75 Query: 61 GQYLLDVIVNGQSISPASLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESLDKV 120 G Y +D+ +N + A+ ++F S CLT + MGL S+ + Sbjct: 76 GTYRVDIYLNNGYM--ATRDVTFNTGDSEQGI------VPCLTRAQLASMGLNTASVSGM 127 Query: 121 VYWHDGQCADF-HGLPGVDIRPDTGAGVLRINMPQAWLEYSDATWLPPSRWDDGIPGLML 179 D C + + D G L + +PQA++ ++PP WD GI +L Sbjct: 128 NLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLL 187 Query: 180 DYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNFTW 239 +YN +G +N GG+SH N G N+G WRLR + S S + + + Sbjct: 188 NYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSS--DSSSGSKNKWQH 245 Query: 240 SRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIA 299 +L R I R+ LTLG+ DIF ++ GA L SDD MLP RG+AP I GIA Sbjct: 246 INTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIA 305 Query: 300 ETNARVVVSQQGRVLYDSMVPAGPFSIQDLD-SSVRGRLDVEVIEQNGRKKTFQVDTASV 358 A+V + Q G +Y+S VP GPF+I D+ + G L V + E +G + F V +SV Sbjct: 306 RGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSV 365 Query: 359 PYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGLSNQWSLYGGAVLAGDYNALAA 418 P L R G RY + +G R + E P F GL W++YGG LA Y A Sbjct: 366 PLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNF 425 Query: 419 GAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSERN 478 G G ++G G LS D+TQ+ + + + G+S R Y+K + + +I GYR+S Sbjct: 426 GIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 479 YMTMEQYLNARYR--------------------NDYSSREKEMYTVTLNKNVADWNTSFN 518 Y +R + + ++ +T+ + + + + Sbjct: 486 YFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS-TLY 544 Query: 519 LQYSRQTYWDIRKTD-YYTVSVNRYFNVFGLQGVAVGLSASRSKYLGRD--NDSAYLRIS 575 L S QTYW D + +N F + LS S +K + + L ++ Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFE-----DINWTLSYSLTKNAWQKGRDQMLALNVN 599 Query: 576 VPLGT------------GTASYSGSMSND-RYVNMAGYTDM-FNDGLDSYSLNAGLNSGG 621 +P +ASYS S + R N+AG D SYS+ G GG Sbjct: 600 IPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGG 659 Query: 622 GLTSQRQINAYYSHRSPLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGG 681 S A ++R N + S SGG G L G Sbjct: 660 DGNSGSTGYATLNYRGGYGNANIG-YSHSDDIKQLYYGVSGGVLAHANGVTL--GQPLND 716 Query: 682 TRLLVDTDGVGGVPVDGGQVV-TNRWGTGVVTDISSYYRNTTSVDLKRLPDDVEATRSVV 740 T +LV G V+ V T+ G V+ + Y N ++D L D+V+ +V Sbjct: 717 TVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVA 776 Query: 741 ESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLAWLS 800 T GAI +F G +L L + PFGA VTSE + G+VAD G +LS Sbjct: 777 NVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLS 835 Query: 801 GVTPGETLSVNW--DGKIQCQVNVPETAISDQQLL----LPC 836 G+ + V W + C N S QQLL C Sbjct: 836 GMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 31.5 bits (71), Expect = 0.001 Identities = 41/173 (23%), Positives = 75/173 (43%), Gaps = 29/173 (16%) Query: 29 GMSLPEYWG----EEHVWWDGRAAFHGEVVRPACTLAMEDAWQIIDMGETPVRDL-QNGF 83 G+ LP G +HV F G+++ PACT+ + ++ G+ +++L Q+G Sbjct: 6 GLCLPVMLGAVLMSQHVHAADNLTFKGKLIIPACTVQNAE----VNWGDIEIQNLVQSG- 60 Query: 84 SGPERKFSLRLRNCEFNSQGGNLFSDSRIRVTFDGVRGET---PDKFNLSGQAKGINLQI 140 G ++ F++ + NC ++ ++ +T +G G + P+ SG I L Sbjct: 61 -GNQKDFTVDM-NCPYS------LGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYN 112 Query: 141 ADARGNIARAGKV-MPAIP--LTGNEEALDYTLRIVR----NGKKLEAGNYFA 186 ++ I A + P +TG A TL N + L+AG + A Sbjct: 113 SNN-SGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSA 164
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.0 bits (158), Expect = 2e-15 Identities = 34/197 (17%), Positives = 66/197 (33%), Gaps = 13/197 (6%) Query: 1 MSTYENILRITDTLIQQRGFLGFSYADLEKEIGIRKASIHHHFPRKTDLGIAYCQYKTEV 60 T ++IL + L Q+G S ++ K G+ + +I+ HF K+DL + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 FDRLNITLHN--VSSGVQRLRTYLDA-FAGCAERGEMCGIYAMLSDSHQFSPELQ--EAV 115 L + + LR L + ++ +F E+ + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 116 SQLAHQEI-QMIKDIITSGQNSGEFKTVLLPDELAVIVCSTLKGALMLNRLPPHDTYSGT 174 + E I+ + + L+ A+I+ + G LM N L ++ Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG-LMENWLFAPQSFDLK 188 Query: 175 ------VNALIKMLDTR 185 V L++M Sbjct: 189 KEARDYVAILLEMYLLC 205
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.7 bits (67), Expect = 0.003 Identities = 10/51 (19%), Positives = 20/51 (39%), Gaps = 2/51 (3%) Query: 34 TEDIAVTDAWLRAHPDDVEVIPLCRIQPRQYSHEQHIEELRAALARMLHMH 84 I + + + H D+E+ R+ +S+ Q A L L ++ Sbjct: 73 KGPILMLEGFF--HAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIY 121
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 10/78 (12%), Positives = 31/78 (39%), Gaps = 8/78 (10%) Query: 19 QAEALRQKDQQLSLVEETEAFLRSALARAEEKIEEDEREIEHLRA--QIEKLRRMLFGTR 76 +A L + ++ +R +L + + E+ + + Q+ ++ F Sbjct: 183 RALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQ---FE-- 237 Query: 77 SEKLRREVEQAEALLKQR 94 ++L+ E + A++ + Sbjct: 238 -DRLQFENQINPAIMDVQ 254
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 286 bits (733), Expect = 5e-81 Identities = 192/900 (21%), Positives = 322/900 (35%), Gaps = 215/900 (23%) Query: 35 NRKLVATMLSLAVAGTVNA---ANIDISNVWARDYLDLAQNKGIFQPGATDVTITLKNGD 91 N+K ++L VA + A + +V + + D A+NKG F GAT+V + KN Sbjct: 3 NKKFKLNFIALTVAYALTPYTEAALVRDDVDYQIFRDFAENKGKFSVGATNVLVKDKNNK 62 Query: 92 KF--SFHN-LSIPDFSGAAAS-GAATAIGGSYSVTVAH-----------------NKKNP 130 + N + + DFS AT I Y V V H N N Sbjct: 63 DLGTALPNGIPMIDFSVVDVDKRIATLINPQYVVGVKHVSNGVSELHFGNLNGNMNNGNA 122 Query: 131 QAAETQVYAQSSYRVVDRRNSN-------------------DFEIQRLNKFVVETVGATP 171 +A ++ Y V++ D+ + RL+KFV E Sbjct: 123 KAHRDVSSEENRYFSVEKNEYPTKLNGKTVTTEDQTQKRREDYYMPRLDKFVTEVAPIEA 182 Query: 172 AETNPTTYSDALERYGIVTSDGSKKIIGFRAGSGGTSFI----NGESKISTNSAYS---- 223 + + +D +K R GSG + FI + S I N Sbjct: 183 STAS---------SDAGTYNDQNKYPAFVRLGSG-SQFIYKKGDNYSLILNNHEVGGNNL 232 Query: 224 -------HDLLSASLFEVTQWDSYGMMIYKNDKT-------------FRNLEIFGDSGSG 263 ++ + ++V ++ G++ + N K N + GDSGS Sbjct: 233 KLVGDAYTYGIAGTPYKVN-HENNGLIGFGNSKEEHSDPKGILSQDPLTNYAVLGDSGSP 291 Query: 264 AYLYDNKLEKWVLVGTTHGIASVNGDQLTWITKYNDKLVSELKDTYS----------HKI 313 ++YD + KW+ +G+ A N Y + ++ + S + Sbjct: 292 LFVYDREKGKWLFLGSYDFWAGYNKKSWQEWNIYKSQFTKDVLNKDSAGSLIGSKTDYSW 351 Query: 314 NLNGNNVTIKNTDITLHQNNADTTGTQEKITKDKDIVFTNGGDVLFKDNLDFGSGGIIFD 373 + NG TI + +L N D ++K K + F G + +N+D G+GG+ F+ Sbjct: 352 SSNGKTSTITGGEKSL---NVDLADGKDKPNHGKSVTFEGSGTLTLNNNIDQGAGGLFFE 408 Query: 374 EGHEYNINGQGFTFKGAGIDIGKESIVNWNALYSSDDVLHKIGPGTLNVQKKQG--ANIK 431 +E T+KGAG+ + + V W D L KIG GTL V+ ++K Sbjct: 409 GDYEVKGTSDNTTWKGAGVSVAEGKTVTWKVHNPQYDRLAKIGKGTLIVEGTGDNKGSLK 468 Query: 432 IGEGNVILNEEG------TFNNIYLASGNGKVILNKDNSLGNDQYAGIFFTKRGGTLDLN 485 +G+G VIL ++ F ++ + SG ++LN D + + I+F RGG LDLN Sbjct: 469 VGDGTVILKQQTNGSGQHAFASVGIVSGRSTLVLNDDKQVDPN---SIYFGFRGGRLDLN 525 Query: 486 GHNQTFTRIAATDDGTTITNSDTTKEAVLAINNEDSYIYHGNINGNIKLTHNINSQD--- 542 G++ TF I DDG + N + T + + I E + N +NI++ D Sbjct: 526 GNSLTFDHIRNIDDGARLVNHNMTNASNITITGESLI-----TDPNTITPYNIDAPDEDN 580 Query: 543 ------KKTNAKL----------ILDGSVNTKNDVEV----SNASLTMQGHATEHAI--- 579 K +L L +T++++ SN + G ++ A Sbjct: 581 PYAFRRIKDGGQLYLNLENYTYYALRKGASTRSELPKNSGESNENWLYMGKTSDEAKRNV 640 Query: 580 ------------------------------FRSSANHCSLVFLCGTD------------- 596 F+ + + GT+ Sbjct: 641 MNHINNERMNGFNGYFGEEEGKNNGNLNVTFKGKSEQNRFLLTGGTNLNGDLTVEKGTLF 700 Query: 597 ----WVTVLKETESSYNKKFNSDYKSNNQQTSFDQPDWKTGVFKFDTLHLN-NADFSISR 651 ++ + K + + NN + DW FK T+++ NA R Sbjct: 701 LSGRPTPHARDIAGISSTKKDPHFAENN--EVVVEDDWINRNFKATTMNVTGNASLYSGR 758 Query: 652 N-ANVEGNISA-NKSAITIGDKN-------------VYIDNLAGKNITNNGFDFKQ---- 692 N AN+ NI+A NK+ + IG K V + N F+ Sbjct: 759 NVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSFNPTNLRGN 818 Query: 693 ---TISTNLSIGETKFTGGI-TAHNSQIAIGDQAVVTLNGATF-----LDNTPISIDKGA 743 T S N +G+ G I + NSQ+ + + + L G + L N I ++ Sbjct: 819 VNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSAD 878 Score = 40.0 bits (93), Expect = 6e-05 Identities = 52/204 (25%), Positives = 89/204 (43%), Gaps = 42/204 (20%) Query: 792 GNANFI-ARNMASVTGNIYADDAATITLGQPETETPTISSAYQAW--------AETLLYG 842 GNA+ RN+A++T NI A + A + +G +T + S Y + ++ L Sbjct: 750 GNASLYSGRNVANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNS 809 Query: 843 FD-TAYRGAITAPK--------------------ATVSMN-NAIWHLNSQSSINRLETKD 880 F+ T RG + + + V + N+ WHL S +++L+ + Sbjct: 810 FNPTNLRGNVNLTESANFVLGKANLFGTIQSRGNSQVRLTENSHWHLTGNSDVHQLDLAN 869 Query: 881 SMVRFTGDNG-----KFTTLTVNNLTIDDSAFVLRANLA--QADQLVVNKSLSGKNNLLL 933 + + K+ TLTVN+L+ + S + L +L+ Q D++VV KS +G L + Sbjct: 870 GHIHLNSADNSNNVTKYNTLTVNSLSGNGSFYYL-TDLSNKQGDKVVVTKSATGNFTLQV 928 Query: 934 VDFIEKNGNSNGLNIDLVSAPKGT 957 D K G N + L A K Sbjct: 929 AD---KTGEPNHNELTLFDASKAQ 949
>PF04183#IucA / IucC family Length = 580 Score = 816 bits (2109), Expect = 0.0 Identities = 566/580 (97%), Positives = 571/580 (98%) Query: 1 MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGAQWRFIAERGIWGWLWI 60 MNHKDWD VNRRLVAKMLSE+EYEQVFHAESQGDD YCINLPGAQWRFIAERGIWGWLWI Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGAQWRFIAERGIWGWLWI 60 Query: 61 DAQTLRCTDEPVLAQTLLMQLKPVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD 120 DAQTLRC DEPVLAQTLLMQLK VLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD Sbjct: 61 DAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASD 120 Query: 121 LINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC 180 LINL+ADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC Sbjct: 121 LINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRC 180 Query: 181 DNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG 240 DN++DI QLLTAAMDPQEF RFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG Sbjct: 181 DNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG 240 Query: 241 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR 300 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR Sbjct: 241 RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASR 300 Query: 301 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK 360 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK Sbjct: 301 WLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLK 360 Query: 361 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI 420 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI Sbjct: 361 PDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALI 420 Query: 421 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEAFPEMDSLPQEVRDVTSRLSADYLIHDL 480 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKE FPEMDSLPQEVRDVTSRLSADYLIHDL Sbjct: 421 AHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDL 480 Query: 481 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMNKHPQMSERFALFSLFRPQIIR 540 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYM KHPQMSERFALFSLFRPQIIR Sbjct: 481 QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIR 540 Query: 541 VVLNPVKLTWPDQDGGSRMLPNYLENLQNPLWLVTQEYES 580 VVLNPVKLTWPD DGGSRMLPNYLE+LQNPLWLVTQEYES Sbjct: 541 VVLNPVKLTWPDLDGGSRMLPNYLEDLQNPLWLVTQEYES 580
>PF04183#IucA / IucC family Length = 580 Score = 340 bits (874), Expect = e-112 Identities = 104/480 (21%), Positives = 177/480 (36%), Gaps = 46/480 (9%) Query: 58 ELIIPLDEQKSLHFRVAYFSPTQHHRF-----AFPARLVTASGSYPVDFTTLSRLIIDKL 112 E + + Q + + P RF + + A D L++ ++ +L Sbjct: 24 EQVFHAESQGDDRYCIN--LPGAQWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQL 81 Query: 113 RHQLFLPVPLCETFHQRVLESHAHTQQAIDARHDWTALREKALNFGEAEQALLTGHAFHP 172 + L + Q + + Q + AR +A LN + Q LL+GH Sbjct: 82 KQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNA-DRLQCLLSGHPKFV 140 Query: 173 APKSHEPFNRREAERYLPDMAPHFPLRWFSVDKTQIAGES-LHLNLQQRLTRFAAENAPQ 231 K + + ERY P+ A F L W +V + + +++ Q LT A PQ Sbjct: 141 FNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLT---AAMDPQ 197 Query: 232 LLNELS--------DNQWLF-PLHPWQGEYLLQQGWCQALVAKGLIKDLGEAGTSWLPTT 282 S D+ WL P+HPWQ + + + A+G + LGE G WL Sbjct: 198 EFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADF-AEGRMVSLGEFGDQWLAQQ 256 Query: 283 SSRSLYCATSRD--MIKFSLSVRLTNSIRTLSVKEVKRGMRLARLAQ----TDGWQMLQ- 335 S R+L A+ R IK L++ T+ R + + + G +R Q TD + Sbjct: 257 SLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSG 316 Query: 336 ---VRFPTFRVMQEDGWAGLLDLNGNIMQESLFALRENLLVDQPKSQTNVLVSLTQAAPD 392 + P + +G+A L + REN ++ VL++ + Sbjct: 317 AVILGEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDE 376 Query: 393 GGDSLLVSAVKRLSDRLGITVQQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILV 452 L + + DR G+ A W+ + V+ PL+ YG+ L+AH QNI + Sbjct: 377 NNQPLAGAYI----DRSGLD----AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITL 428 Query: 453 QMLGDLPVGFIYRDCQGSAFMPHATDWLDSIGEAQAENIFTHEQLLRYFPYYLLVNSTFA 512 M +P + +D QG M + + E + L++ Sbjct: 429 AMKEGVPQRVLLKDFQGD--MRLVKEEFPEMDSLPQE----VRDVTSRLSADYLIHDLQT 482
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.5 bits (113), Expect = 5e-08 Identities = 81/375 (21%), Positives = 135/375 (36%), Gaps = 41/375 (10%) Query: 20 FSAGLLGIGQNGLLVVLPVLVIQTNLSLSV---WAALLMLGSMLFLPSSPWWGKQISRTG 76 + L +G ++ VLP L+ S V + LL L +++ +P G R G Sbjct: 12 STVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFG 71 Query: 77 SKPVVLWALGGYGISFTLLGLGSVLMATSAITTAVGLGILIIARIAYGLTVSAMVPACQV 136 +PV+L +L G + + ++ L +L I RI G+T + A Sbjct: 72 RRPVLLVSLAGAAVDYAIMATAPFLW------------VLYIGRIVAGITGATGAVAGAY 119 Query: 137 WALQRAGEGNRMAALATISSGLSCGRLFGPLCAAAMLAIHPLAPLGLLMAAPVLALLMLL 196 A R +S+ G + GP+ M P AP A L L Sbjct: 120 IA-DITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 197 RL------PGTPPQPTPEYKSVSLKRDCLPYLLCAILLAAAVSMMQLGLSPAL------T 244 L P ++ R + A L+A M +G PA Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 245 RQFATDTTAISQQVAWLLGLSAVAALIAQFGVLRPQRLTPVALLLSAGVLMSGGLAIMLS 304 +F D T I +A L ++A + G + + AL+L +G + + + Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMI-TGPVAARLGERRALMLGMIADGTGYILLAFA 297 Query: 305 EQLWLFYPGCAVLSFGAALATPAYQLLLNDKLADGAGAGWLATSHTLGYGLCALLVPLVS 364 + W+ +P +L+ G + PA Q +L+ + D G L L L S Sbjct: 298 TRGWMAFPIMVLLASG-GIGMPALQAMLS-RQVDEERQGQLQ----------GSLAALTS 345 Query: 365 KTGVAIALIMAALFA 379 T + L+ A++A Sbjct: 346 LTSIVGPLLFTAIYA 360
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 29.5 bits (66), Expect = 0.012 Identities = 24/135 (17%), Positives = 46/135 (34%), Gaps = 24/135 (17%) Query: 125 YQATPDLNLALRYRYDWKAFRQTDLDGNRARNDQHQFDGYVTYKINDSWLFAWQTTVYTK 184 YQ P + + Y + + + ++ + Q + Y I D +YT+ Sbjct: 64 YQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDL------DIYTR 117 Query: 185 V---------NNFKYGNHKKTATENAFVL--QYKMSPVFTPYIEYDYLDKQGVYKGKDNK 233 + + YG + T F +Y ++P +EY + + G + Sbjct: 118 LGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIGTR 177 Query: 234 HEN-------SYRVG 241 +N SYR G Sbjct: 178 PDNGMLSLGVSYRFG 192
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 63.7 bits (155), Expect = 5e-13 Identities = 64/401 (15%), Positives = 145/401 (36%), Gaps = 34/401 (8%) Query: 43 LLDGFDFVLISLVLTEVQHEFGLTTIEAASLISAAFISRWFGGLAIGALSDKMGRRMAMV 102 + +++++ L ++ ++F + +A ++ G G LSD++G + ++ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 103 LSIVLFSLGTLACGLAPGYAVMFI-ARIVIGLGMAGEYGSSVTYVIESWPVHLRNKASGF 161 I++ G++ + + + I AR + G G A + V P R KA G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 162 LISGFSIGGGLAAQVYSIVVPLWGWRSLFFVGMLPILFAFYLRKNLPESDDWQKRQQENK 221 + S ++G G+ + ++ W L + M+ I+ +L K L + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKE----------- 192 Query: 222 PVRTMVDILYREKNKYINILLSCIAFACLYVCFSGVTANAALITVMALCCAAVFIS---- 277 VR + I+L + + T+ + ++++ +F+ Sbjct: 193 -VRI------KGHFDIKGIILMSVGIVFFML---FTTSYSISFLIVSVLSFLIFVKHIRK 242 Query: 278 ----FIYQGMGKRWPTGIMLMLVVMFCFLYGWPLQAFLPTWLKVDMQYSPETVALIFMLA 333 F+ G+GK P ++ +L F + +P +K Q S + + + Sbjct: 243 VTDPFVDPGLGKNIPF-MIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 334 G-FGSAAGSCIGGFMGDWLGTRK-AYVISLLIGQLVIIPVFLVDRDYVWLLGLLIFTQQV 391 G IGG + D G + + + FL++ ++ +++F Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG- 360 Query: 392 FGQGIGALVPKIISGYFNVEQRAAGLGFIYNVGSLGGACAP 432 ++ I+S ++ AG+ + L Sbjct: 361 GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGI 401
>PF03309#Bvg accessory factor Length = 271 Score = 32.0 bits (73), Expect = 0.002 Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 4/67 (5%) Query: 1 MITLAVDIGGTKISAALISDD---GSFLLKKQISTPHERCPDEMTGALRLLVSEMKGTAE 57 M+ LA+D+ T LIS + + +I T E DE+ + L+ + Sbjct: 1 ML-LAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAERLT 59 Query: 58 RFAVAST 64 + ST Sbjct: 60 GASGLST 66
>PF02370#M protein repeat Length = 168 Score = 31.6 bits (71), Expect = 0.002 Identities = 20/103 (19%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 18 EQAEALRQRDLQLSLVEETEAFLRSALARAEEKIEEEEREIEYLRAQIEKLRRMLFGTRS 77 + +++ R+ D Q + LR + ++KIEE E+E + + + E+ + + Sbjct: 38 DSSDSKRENDPQYRALMGENQDLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQD 97 Query: 78 EKLQREVEQAEAQLKQREQESDRYSGREDDPQVPRQLRQSRHR 120 + Q + ++ + + +Q E E + + Q+ RQ +R Sbjct: 98 KHYQEQQKKHQQEQQQLEAEKQKL---AKEKQISDASRQGLNR 137
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 41.6 bits (97), Expect = 2e-05 Identities = 87/417 (20%), Positives = 139/417 (33%), Gaps = 46/417 (11%) Query: 311 QNTGGALVTSTAATVTGTNRLGAFSVVAGKADNVVLENGGRLDVLSGHTATNTRVDDGGT 370 ++ + V VT GA + V+ + + +GG + G A + Sbjct: 194 EDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGGH--ITGGRAAGVAAMQGAVV 251 Query: 371 ----LDIRNGGAATTVSMGNGGVLLADSGAAVSGTRSDGKAFSIGGGQA----DALMLEK 422 IR G A ++ G V G AV G G + G +E Sbjct: 252 HLQRATIRRGDAPAGGAVPGGAVP----GGAVPGGFGPGGFGPVLDGWYGVDVSGSSVEL 307 Query: 423 GSSFTLNAGDTATDTTVNGGLFTARGGTLAGTTTLNNGAILTLSGKTV---NNDTLTIR- 478 S A G T GG+L+ G ++ G L+I Sbjct: 308 AQSIVEAPELGAAIRVGRGARVTVSGGSLSAPH----GNVIETGGARRFAPQAAPLSITL 363 Query: 479 EGDALLQGGSLTGNGSVEKSGSGTLTVSNTTLTQKAVNLNEGTLTLNDSTVTTDVIAQRG 538 + A QG +L E LT++ Q + E S DV Sbjct: 364 QAGAHAQGKALLYRVLPEPV---KLTLTGGADAQGDIVATELPSIPGTSIGPLDVALASQ 420 Query: 539 TALKLTGSTVLNGAIDPTNVTLASDATWNIPDNATVQSVVDDLSHAGQIHF-TSSRTGTF 597 GA + +ATW + DN+ V ++ L+ G + F + G F Sbjct: 421 ARWT--------GATRAVDSLSIDNATWVMTDNSNVGAL--RLASDGSVDFQQPAEAGRF 470 Query: 598 VPATLKVKNLNGQNGTISLRVRPDMAQNNADRLVIDGGRATGKTILNLVNAGNSASGLAT 657 L V L G +G + V D+ + D+LV+ A+G+ L + N+G+ + T Sbjct: 471 --KVLTVNTLAG-SGLFRMNVFADLGLS--DKLVVMQD-ASGQHRLWVRNSGSEPASANT 524 Query: 658 SGKGIQVVEAINGATTEEGAFVQGNRLQAGAFNYSLNRDSDESWYLRSENAYRAEVP 714 + V + A T A ++ G + Y L + + W L A A P Sbjct: 525 L---LLVQTPLGSAATFTLANK-DGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKP 577
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 32.0 bits (72), Expect = 0.004 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 5/91 (5%) Query: 4 SLAHENARLRALLQTQQDTIRQMAEYNRLLSQRVAAYASEINRLKALVAKLQRMQFGKSS 63 + A A AL Q +D + + +N + A N A+ A+ +R++ K+ Sbjct: 79 AQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANN--AAMQAEDERLRLAKAE 136 Query: 64 EKLR---AKTERQIQEAQERISALQEEMAET 91 EK R E+ QEA++R ++ E AET Sbjct: 137 EKARKEAEAAEKAFQEAEQRRKEIEREKAET 167
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 44.5 bits (105), Expect = 5e-07 Identities = 17/90 (18%), Positives = 33/90 (36%), Gaps = 7/90 (7%) Query: 238 AFHQY-KGRWAKAIDAYEKHTSINPLCAELYYRLGLSYDRCYQWDKAAENYRKALSLDEN 296 AF+QY G++ A ++ ++ + + LG Q+D A +Y +D Sbjct: 43 AFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102 Query: 297 HPYWHYRLGFVL------ERSQKYLDAAVA 320 P + + L ++ L A Sbjct: 103 EPRFPFHAAECLLQKGELAEAESGLFLAQE 132 Score = 33.0 bits (75), Expect = 0.004 Identities = 14/83 (16%), Positives = 32/83 (38%), Gaps = 1/83 (1%) Query: 265 ELYYRLGLSYDRCYQWDKAAENYRKALSLDENHPYWHYRLGFVLERSQKYLDAAVAYQFA 324 E Y L + + +++ A + ++ LD + LG + +Y A +Y + Sbjct: 37 EQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYG 96 Query: 325 AQSNIKHISIWYYRSGYAYAKAN 347 A +IK + + + + Sbjct: 97 AIMDIK-EPRFPFHAAECLLQKG 118 Score = 29.9 bits (67), Expect = 0.044 Identities = 16/84 (19%), Positives = 31/84 (36%), Gaps = 2/84 (2%) Query: 15 EYINGIS--LYKKKEWEKALLFFEKSIIKKTKHAESYFKAGICNLKLHRYEEAFKYISKA 72 + G+ +++ A+ + I K F A C L+ EA + A Sbjct: 71 RFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLA 130 Query: 73 LELEPSNIQWKEQLEQCARHLDKL 96 EL ++KE + + L+ + Sbjct: 131 QELIADKTEFKELSTRVSSMLEAI 154
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 45.6 bits (108), Expect = 6e-09 Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 7/92 (7%) Query: 7 KVITFGTFDVLHIGHINILKRAKKMGDYLIVGVSSDYLNFSKKQRYPVYPETERLEIIR- 65 I G+FD + GH++I++R ++ D + V V N +K+ P++ ERLE I Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLR---NPNKQ---PMFSVQERLEQIAK 55 Query: 66 SLKFVDEVFIEESLELKGEYIKKFKADILVMG 97 ++ + ++ L Y ++ +A ++ G Sbjct: 56 AIAHLPNAQVDSFEGLTVNYARQRQAGAILRG 87
>PF07675#Cleaved Adhesin Length = 1358 Score = 29.7 bits (66), Expect = 0.043 Identities = 24/112 (21%), Positives = 47/112 (41%), Gaps = 16/112 (14%) Query: 35 SAAPLYAADVPANTPLAPQQVFRYNNHSDPGTLDPQKVEENTAAQIVL------------ 82 + PL+ +N A + + ++DP + Q + ++V+ Sbjct: 421 ATGPLFTGTASSNLYSANFE-YLTPANADP-VVTTQNIIVTGQGEVVIPGGVYDYCITNP 478 Query: 83 DLFEGLVWMDGEGQVQPAQAERWEILDGGKRYIFHLRSGLQWSDGQPLTAED 134 + G +W+ G+G QPA+ + + + GK+Y F +R DG + ED Sbjct: 479 EPASGKMWIAGDGGNQPARYDDF-AFEAGKKYTFTMRR-AGMGDGTDMEVED 528
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 5e-23 Identities = 30/129 (23%), Positives = 56/129 (43%) Query: 2 RILLIEDDMLIGDGIKTGLSKMGFRVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRD 61 IL+ +DD I + LS+ G+ V + + + D V+ D+ +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNG 121 +L ++ PVL+++A++ ++ GA DYL KPF L E+ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 QASNELRHG 130 + S Sbjct: 125 RPSKLEDDS 133
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 1e-05 Identities = 38/176 (21%), Positives = 62/176 (35%), Gaps = 29/176 (16%) Query: 284 DRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKIDVRLTLKANG 343 +A ++ L L R SL ++ L D L +V+D Y + + RL + Sbjct: 191 TKAREMLTSLSELMRY-SLRYSNA-RQVSLADEL--TVVDSYLQLASIQFEDRLQFENQI 246 Query: 344 IKRTGQ----PLLLSLLVRNLLDNAVRYSPQGSVVDVTLNADN----FIVRDNGPGVTPE 395 P+L+ LV N + + + PQG + + DN V + G Sbjct: 247 NPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN 306 Query: 396 ALARIGERFYRPPGQTATGSGLGLSIV-QRIAKLHGMNVDFG-NAEQGGFEAKVSW 449 T +G GL V +R+ L+G + +QG A V Sbjct: 307 ---------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 689 bits (1780), Expect = 0.0 Identities = 234/878 (26%), Positives = 401/878 (45%), Gaps = 70/878 (7%) Query: 14 HAIKNALSG------VVCSLLFVLPVH--AVEFNVDMIDAEDRENIDISRFEKKGYIPPG 65 H K+ L+G V C+ P+ + FN + + + D+SRFE +PPG Sbjct: 17 HIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPG 76 Query: 66 RYLVRVQINKNMLPQTLILEWVKADNESGSLLCLTKENLTNFGLNTEFIESLQNIAGSEC 125 Y V + +N + + + D+E G + CLT+ L + GLNT + + +A C Sbjct: 77 TYRVDIYLNNGYMATRDV-TFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDAC 135 Query: 126 LDLSQR-QELTTRLDKATMILSLSVPQAWLKYQATNWTPPEFWDTGITGFILDYNVYASQ 184 + L+ + T +LD L+L++PQA++ +A + PPE WD GI +L+YN + Sbjct: 136 VPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNS 195 Query: 185 YAPHHGDSTQNVSSYGTLGFNLGAWRLRSDYQYNQNFADGRSVNRDS-EFARTYLFRPIP 243 G ++ G N+GAWRLR + ++ N +D S +++ + T+L R I Sbjct: 196 VQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDII 255 Query: 244 SWSSKFTMGQYDLSSNLYDTFHFTGASLESDESMLPPDLQGYAPQITGIAQTNAKVTVAQ 303 S+ T+G +++D +F GA L SD++MLP +G+AP I GIA+ A+VT+ Q Sbjct: 256 PLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQ 315 Query: 304 NGRVLYQTTVAPGPFTISDL-GQSFQGQLDVTVEEEDGRTSTFQVGSASIPYLTRKGQVR 362 NG +Y +TV PGPFTI+D+ G L VT++E DG T F V +S+P L R+G R Sbjct: 316 NGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTR 375 Query: 363 YKTSLGKPTSVGHNDINNPFFWTAEASWGWLNNVSLYGGGMFTADDYQAITTGIGFNLNQ 422 Y + G+ S P F+ + G ++YGG AD Y+A GIG N+ Sbjct: 376 YSITAGEYRSGNAQQE-KPRFFQSTLLHGLPAGWTIYGGTQL-ADRYRAFNFGIGKNMGA 433 Query: 423 FGSLSFDVTGADASLQQQNSGNLRGYSYRFNYAKHFESTGSQITFAGYRFSDKDYVSMSE 482 G+LS D+T A+++L G S RF Y K +G+ I GYR+S Y + ++ Sbjct: 434 LGALSVDMTQANSTLPDD--SQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFAD 491 Query: 483 YLSSRNGDESID--------------------NEKESYVISLNQYFETLELNSYLNVTRN 522 SR +I+ N++ +++ Q YL+ + Sbjct: 492 TTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT-STLYLSGSHQ 550 Query: 523 TYWDS-ASNTNYSVSVSKNFDIGDFKGISASLAVSRIR--WDDDEENQYYFSFSLPL--- 576 TYW + + + ++ F+ I+ +L+ S + W + + ++P Sbjct: 551 TYWGTSNVDEQFQAGLNTA-----FEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHW 605 Query: 577 --------QQNRNISYSMQRTGSSNTSQMISWYDS--SDRNNIWNISASATDDNIRDGEP 626 ++ + SYSM + + + Y + D N +++ + Sbjct: 606 LRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGS 665 Query: 627 TLRGSYQHYSPWGRLNINGSVQPNQYNSVTAGWYGSLTATRHGVALHDYSYGDNARMMVD 686 T + + +G NI S + + G G + A +GV L ++ ++V Sbjct: 666 TGYATLNYRGGYGNANIGYSHS-DDIKQLYYGVSGGVLAHANGVTLGQPL--NDTVVLVK 722 Query: 687 TDGISGIEINSNRTV-TNGLGIAVIPSLSNYTTSMLRVNNNDLPEGVDVENSVIRTTLTQ 745 G ++ + V T+ G AV+P + Y + + ++ N L + VD++N+V T+ Sbjct: 723 APGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTR 782 Query: 746 GAIGYAKLNATTGYQIVGVIRQENGRFPPLGVNVTDKATGKDVGLVAEDGFVYLSGIQEN 805 GAI A+ A G +++ + N + P G VT + + G+VA++G VYLSG+ Sbjct: 783 GAIVRAEFKARVGIKLLMTLTH-NNKPLPFGAMVTS-ESSQSSGIVADNGQVYLSGMPLA 840 Query: 806 SILHLTWGD---NTCEVT---PPNQSNISESAIILPCK 837 + + WG+ C PP + + C+ Sbjct: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 49.0 bits (117), Expect = 3e-11 Identities = 15/42 (35%), Positives = 23/42 (54%), Gaps = 2/42 (4%) Query: 1 MNNRSNSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGK 42 N E I+S+ +++V V+PTNEE MIA D + + Sbjct: 358 KNKVRGE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.014 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 4 VLITGATGLVGGHLLRMLINEP 25 L+TGA G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 73.4 bits (180), Expect = 2e-15 Identities = 70/313 (22%), Positives = 110/313 (35%), Gaps = 77/313 (24%) Query: 396 IMGHVDHGKTSLLDYI-----RSTKVASGEAG-------------GITQHIGAYHVETEN 437 ++ HVD GKT+L + + T++ S + G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 438 GMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAGVPVVVAV 497 + +DTPGH F + R D +L+++A DGV QT + G+P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 498 NKIDKPEADPDRV----KNELSQYGI-----------------LPEEWG----------- 525 NKID+ D V K +LS + E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 526 ---------------GESQFV---------HVSAKAGTGIDELLDAILLQAEVLELKAVR 561 ES H SAK GID L++ I + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 562 KGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVL-CGFEYGRVRAMRNELGQEVLEA 620 + G V + + R +A + + G LH D V E ++ M + E+ + Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 621 GPSIPVEILGLSG 633 + EI+ L Sbjct: 306 DKAYSGEIVILQN 318
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 7e-13 Identities = 26/115 (22%), Positives = 45/115 (39%), Gaps = 4/115 (3%) Query: 528 VLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDI 587 +L+ +D V L + G V + G+ DLV+ D+ +PD D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 588 SRALTKRYPREDLPPLVALTA-NVLKDKQEYLNAGMDDVLSKPLSVPALTAMIKK 641 + K P P++ ++A N + G D L KP + L +I + Sbjct: 66 LPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 56.8 bits (137), Expect = 1e-10 Identities = 65/408 (15%), Positives = 139/408 (34%), Gaps = 33/408 (8%) Query: 40 LLDGFDFVLIALVLTEVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMV 99 + +++ + L ++ +F + +A ++ G + G + D+ G + ++ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 100 TSIVLFSAGTLACGFAPGYITMFI-ARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGF 158 I++ G++ + ++ I AR + G G A V PK R KA G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 159 LISGFSVGAVVAAQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKA 218 + S ++G V + ++ W L I ++ II +L K + + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR--------- 194 Query: 219 PVRTMVDILYRGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQ 278 +G I I++ + IV+VL L IF+ + + Sbjct: 195 ---------IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL---IFVKHIRK 242 Query: 279 STGK----RWPTGVMLMVVVLFAFLYSWPIQA---LLPTYLKTDLAYDPHTVANVLFFSG 331 T + M+ VL + + ++P +K + +V+ F G Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 332 -FGAAVGCCVGGFLGEWLGTRK-AYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQML 389 + +GG L + G + S + F + W + +++ F Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLET-TSWFMTIIIVFVLGG 361 Query: 390 GQGISGILPKLIGGYFDTDQRAAGLGFTYNVGALGGALAP-ILGALIA 436 ++ ++ + AG+ L I+G L++ Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.5 bits (61), Expect = 0.026 Identities = 8/27 (29%), Positives = 16/27 (59%) Query: 127 IEADKSGTVKAILVESGQPVEFDEPLV 153 I+ ++ VK I+V+ G+ V + L+ Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLL 125
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 141 bits (356), Expect = 2e-45 Identities = 49/153 (32%), Positives = 76/153 (49%), Gaps = 18/153 (11%) Query: 3 QQRGFTLLEMMLVLALVAITASVVLFTYGREDAANTRARETAARFTAALELAIDRATLSG 62 +QRGFTLLEMML+L L+ ++A +VL + + + A +T ARF A L R +G Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFP--ASRDDSAAQTLARFEAQLRFVQQRGLQTG 59 Query: 63 QPVGIHFSDSAWRIMV----PGKTP-------SAWRWVPLQEDAADESKNDWGEELSIQL 111 Q G+ W+ +V G P S +RW+PL+ S + G +L++ Sbjct: 60 QFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNLAF 119 Query: 112 ---QPFKPDDSNQPQVVILADGQITPFSLLMAN 141 + + P D P V+I G++TPF L + Sbjct: 120 AQGEAWTPGD--NPDVLIFPGGEMTPFRLTLGE 150
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.9 bits (67), Expect = 0.002 Identities = 17/90 (18%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 14 MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQ--RNAIERMRNETLALWIADNQLQSQD 71 +KQ G TLLE+++ + I +A ++ ++ G + ++ ++ +AL A + + D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK-LD 62 Query: 72 SFGEENTSSSGKELING-----EEWNWRSD 96 + T+ + L+ N+ + Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKE 92
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.1 bits (78), Expect = 1e-04 Identities = 14/45 (31%), Positives = 27/45 (60%), Gaps = 5/45 (11%) Query: 3 NRQQGFTLLEVMAALAIFSMLSVLAFMIFSQVSELHQRSQKEIQK 47 ++Q+GFTLLE+M + I + VLA ++ + + + + + QK Sbjct: 5 DKQRGFTLLEIMVVIVI---IGVLASLVVPNL--MGNKEKADKQK 44
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 151 bits (383), Expect = 4e-47 Identities = 88/262 (33%), Positives = 118/262 (45%), Gaps = 47/262 (17%) Query: 5 LPLFILVGFIAGYFVNVMAYHL---------------SPLEDKTALTFRQVLVH------ 43 L L + G F+NV+ + L +D+ L+ Sbjct: 16 FSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVPRSCCP 75 Query: 44 FWQKKYAWHDTVPLI-------------------------LCVAAAIACALAPFTPIVTG 78 + +PL+ L ++A A+ T Sbjct: 76 HCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAPGWGTL 135 Query: 79 ALFLYFCFALTLSVIDFRTQLLPDKLTLPLLWLGLVFNAQSGLIDLHDAVYGAVAGYGVL 138 A L + L+ ID LLPD+LTLPLLW GL+FN G + L DAV GA+AGY VL Sbjct: 136 AALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGYLVL 195 Query: 139 WCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQTLPMILLIASLGGIGYAIVSQLLQRR 198 W +YW L+ KEG+GYGDFKLLAA GAW GWQ LP++LL++SL G I LL+ Sbjct: 196 WSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLRNH 255 Query: 199 TIPT-IAFGPWLALGSMINLGY 219 I FGP+LA+ I L + Sbjct: 256 HQSKPIPFGPYLAIAGWIALLW 277
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 35.2 bits (81), Expect = 3e-05 Identities = 28/150 (18%), Positives = 59/150 (39%), Gaps = 24/150 (16%) Query: 5 TKVINYLNKLLGNE---LVAINQYFLHARMFKNWGLKRLNDVEYHESIDEM-----KHAD 56 T V N LN L N ++++ +W +K + HE +E+ + D Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRF--------HWYVKGPHFFTLHEKFEELYDHAAETVD 62 Query: 57 RYIERILFLEGLPN--LQDLGKL------NIGEDVEEMLRSDLALELDGAKNLREAIGYA 108 ER+L + G P +++ + EM+++ + + + IG A Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLA 122 Query: 109 DSVHDYVSRDMMIEILRDEEGHIDWLETEL 138 + D + D+ + ++ + E + L + L Sbjct: 123 EENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 4e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 28 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 81 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 82 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 141 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 142 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 201 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 202 AKILELAGFLDSYIPEPE 219 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.7 bits (64), Expect = 0.023 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 164 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 222 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 223 SK 224 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 132 bits (334), Expect = 5e-40 Identities = 79/226 (34%), Positives = 124/226 (54%), Gaps = 9/226 (3%) Query: 28 AAKPATTADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 884 bits (2287), Expect = 0.0 Identities = 398/866 (45%), Positives = 568/866 (65%), Gaps = 28/866 (3%) Query: 19 KRVVPLLLVIMPACSIA--------GMRFNPAFLSGDTEAVADLSRFEKGMTYLPGSYEV 70 R+ + + AC+ A + FNP FL+ D +AVADLSRFE G PG+Y V Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRV 80 Query: 71 EVWVNDSPLLSRTVTFKADD-ENQLIPCLSLADLLSLGINKNALPEQALASSENSCLDLR 129 ++++N+ + +R VTF D E ++PCL+ A L S+G+N ++ L + +++C+ L Sbjct: 81 DIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLA-DDACVPLT 139 Query: 130 IWFPDVHYMPELDAQRLKLTFPQAIIKRDARGYIPPEQWDNGITAFLLNYDFSGN--NDR 187 D ++ QRL LT PQA + ARGYIPPE WD GI A LLNY+FSGN +R Sbjct: 140 SMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNR 199 Query: 188 GDYSSNNYYLNLRAGINIGAWRFRDYSTWSR-----GSNSAGKLEHISSTLQRVIIPFRS 242 +S+ YLNL++G+NIGAWR RD +TWS S S K +HI++ L+R IIP RS Sbjct: 200 IGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRS 259 Query: 243 ELTLGDTWSSSDVFDSVSIRGIKLESDENMLPDSQSGFAPTVRGIAKSRAQVTIKQNGYV 302 LTLGD ++ D+FD ++ RG +L SD+NMLPDSQ GFAP + GIA+ AQVTIKQNGY Sbjct: 260 RLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYD 319 Query: 303 IYQTYMPPGPFEISDLNPTSSAGDLEVTIKESDNSETVYTVPYAAVPILQREGHLKYSTT 362 IY + +PPGPF I+D+ ++GDL+VTIKE+D S ++TVPY++VP+LQREGH +YS T Sbjct: 320 IYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSIT 379 Query: 363 VGQYRSNSYNQKSPYVFQGELIWGLPWDITAYGGAQFSEDYRALALGLGLNLGVFGATSF 422 G+YRS + Q+ P FQ L+ GLP T YGG Q ++ YRA G+G N+G GA S Sbjct: 380 AGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSV 439 Query: 423 DVTQANSSLVDGSKHQGQSYRFLYSKSLVQTGTAFHIIGYRYSTQGFYTLSDTTYQQMSG 482 D+TQANS+L D S+H GQS RFLY+KSL ++GT ++GYRYST G++ +DTTY +M+G Sbjct: 440 DMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNG 499 Query: 483 TVVDPKTLDDKDYVYNWNDFYNLRYSKRGKFQASVSQPFGNYGSMYLSASQQTYWNTDKK 542 ++ + + + D+YNL Y+KRGK Q +V+Q G ++YLS S QTYW T Sbjct: 500 YNIETQDGVIQVKPK-FTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNV 558 Query: 543 DSLYQVGYNTSIKGIYLNVAWNYSKSPGTN-ADKIVSLNVSLPISNWLSSTNDGRSSSNA 601 D +Q G NT+ + I ++++ +K+ D++++LNV++P S+WL S D +S Sbjct: 559 DEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRS--DSKSQWRH 616 Query: 602 MTATYGYSQDNHGQVNQYTGVSGSLLEQHNLSYNIQHGFANQDNSSSGSVG---VNYRGA 658 +A+Y S D +G++ GV G+LLE +NLSY++Q G+A + +SGS G +NYRG Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 659 YGSLNSAYSYDNEGNQQINYGISGALVVHENGLTLSQPLGETNVLIKAPGANNVDVQRGT 718 YG+ N YS+ + +Q+ YG+SG ++ H NG+TL QPL +T VL+KAPGA + V+ T Sbjct: 677 YGNANIGYSHSD-DIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQT 735 Query: 719 GISTDWRGYAVVPYATEYRRNNISLDPMSMNMHTELDITSTEVIPGKGALVRAEFAAHIG 778 G+ TDWRGYAV+PYATEYR N ++LD ++ + +LD V+P +GA+VRAEF A +G Sbjct: 736 GVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVG 795 Query: 779 IRGLFTVRYRNKSVPFGATASAQIKNSSQITGIVGDNGQLYLSGLPLEGVINIQWGDGVQ 838 I+ L T+ + NK +PFGA +++ SSQ +GIV DNGQ+YLSG+PL G + ++WG+ Sbjct: 796 IKLLMTLTHNNKPLPFGAMVTSE---SSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852 Query: 839 QKCQANYKLPETELDNPVSYATLECR 864 C ANY+LP ++ + ECR Sbjct: 853 AHCVANYQLPPESQQQLLTQLSAECR 878
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 32.0 bits (72), Expect = 0.005 Identities = 27/80 (33%), Positives = 36/80 (45%), Gaps = 13/80 (16%) Query: 272 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNILENFDMQKYGF-GSADAMQIMAEAEKYA 330 R P+ G+ R + SMPPP G H +I N+ F Q G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNL--KFFKQFDGYVGGQTAWGILSELEKGR 133 Query: 331 YADRSEYLGDPDFVKVPWQA 350 Y P F WQ+ Sbjct: 134 Y---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 28.7 bits (64), Expect = 0.014 Identities = 12/60 (20%), Positives = 23/60 (38%), Gaps = 4/60 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGDLNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ + W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.046 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 46 IVMVGPSGCGKSTLLRMVAGLERVTTGDI 74 +V+ G G GKSTL+ + GL+ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHF 627
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.3 bits (91), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 50.4 bits (120), Expect = 1e-08 Identities = 44/208 (21%), Positives = 73/208 (35%), Gaps = 21/208 (10%) Query: 20 QTPEK-ETEVQNEQPVVEEIVQAQE----------PVKASEHAVEEQPQ-AHTEAKAETF 67 TP + +V + EEI + E P + +E E Q + T K E Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 68 AADVVEVTEQVAESEK----AQPEAEVVAQPEPVVEETPEPVAIEREELPLSEDVNAEAV 123 A + +VA+ K A + VAQ +ET E + E E Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET- 1116 Query: 124 SPEEWQAEAETVEIVEAAEEEAAKEEITDEEPEAQALAAEVAEEA-VMVVSPAEEDQPVE 182 E E V + ++E ++ EP + +E + A+ +QP + Sbjct: 1117 ---EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 183 EIAQEQEKPTKEGFFARLKRSLLKTKEN 210 E + E+P E S+++ EN Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Score = 50.1 bits (119), Expect = 2e-08 Identities = 38/180 (21%), Positives = 61/180 (33%), Gaps = 11/180 (6%) Query: 19 EQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAKAET-FAADVVEVTEQ 77 TP + TE E E + A+E + + EAK+ EV + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATE-TTAQNREVAKEAKSNVKANTQTNEVAQS 1088 Query: 78 VAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLSEDVNAEAVSPEEWQAEAETVEI 137 +E+++ Q E E E +E E+ V ++ VSP++ Q+E + Sbjct: 1089 GSETKETQTT----ETKETATVEKEEKAKVETEKTQEVPKVTSQ-VSPKQEQSETVQPQ- 1142 Query: 138 VEAAEEEAAKEEITDEEPEAQALAAEVA---EEAVMVVSPAEEDQPVEEIAQEQEKPTKE 194 E A E I + + + A E + V P E V E P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENT 1202 Score = 42.0 bits (98), Expect = 5e-06 Identities = 27/161 (16%), Positives = 56/161 (34%), Gaps = 14/161 (8%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQA-QEPVKASEHAVEEQPQAHTEAKAETFAADVVEVT 75 +E E ++ V+ E+ Q+ E + +E E KA+ EV Sbjct: 1065 NREVAKEAKSNVKAN-TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 76 EQVAE-------SEKAQPEAEVVAQPEPVV--EETPEPVAIEREELPLSEDVNAEAVSPE 126 + ++ SE QP+AE + +P V +E + +++ ++ P Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 127 EWQAEAETVEIVEAAEEEAAKEEITDEEPEAQALAAEVAEE 167 E+ TV + E +P + ++ + Sbjct: 1184 T---ESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Score = 30.4 bits (68), Expect = 0.019 Identities = 21/117 (17%), Positives = 38/117 (32%), Gaps = 3/117 (2%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEHAVEEQPQAHTEAKAETFAADVVEVTE 76 ++ +T + + E E I + Q + A EQP T + E + V Sbjct: 1134 EQSETVQPQAEPARENDPTVNIKEPQSQ--TNTTADTEQPAKETSSNVEQPVTESTTVNT 1191 Query: 77 QVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREEL-PLSEDVNAEAVSPEEWQAEA 132 + E + QP E + +P R + + +V S + A Sbjct: 1192 GNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248
>PF01206#SirA family protein Length = 76 Score = 105 bits (265), Expect = 3e-34 Identities = 24/72 (33%), Positives = 41/72 (56%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRKG 80 + Y + +++ Sbjct: 65 EDGTYHFRLKRA 76
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.8 bits (132), Expect = 3e-10 Identities = 80/398 (20%), Positives = 147/398 (36%), Gaps = 32/398 (8%) Query: 27 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 84 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 85 PHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 143 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 144 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 201 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 202 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 254 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 255 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 310 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 311 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 369 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 370 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 403 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>BORPETOXINB#Bordetella pertussis toxin B subunit signature. Length = 226 Score = 28.1 bits (62), Expect = 0.046 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 10/77 (12%) Query: 204 GQRHVTWARLRGLSDKQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVG- 262 R +T A LRG D Q RH+ R S+ + G ++G GG +I++ PG Sbjct: 53 KTRALTVAELRGSGDLQEYLRHVTRGWSIFALYD-GTYLGGEYGG--VIKD--GTPGGAF 107 Query: 263 ----RYAVSAIFNRDYP 275 + + N P Sbjct: 108 DLKTTFCIMTTRNTGQP 124
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.008 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLALKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 26.4 bits (58), Expect = 0.003 Identities = 10/31 (32%), Positives = 16/31 (51%), Gaps = 3/31 (9%) Query: 9 AMALIVLVGCSTPPPVQKAQRVKGDPLRSLN 39 A+ +LVGC++ Q+ + DPL N Sbjct: 9 ALGTTLLVGCASSGTDQQGRS---DPLEGFN 36
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 27.1 bits (60), Expect = 0.027 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 78 MTCLTVFIISVALLLVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKET 137 MT T II LL L + + GLA FL+ F V I P E Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAP-PNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 138 QVTQEE 143 +++ +E Sbjct: 120 KISMQE 125
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 58.3 bits (141), Expect = 5e-11 Identities = 44/147 (29%), Positives = 69/147 (46%), Gaps = 18/147 (12%) Query: 3 IATAGHVDHGKTTLLQAI---TGV------------NADRLPEEKKRGMTIDLGYAYWPQ 47 I HVD GKTTL +++ +G D E++RG+TI G + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 48 PDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLTGNPML 107 + +V ID PGH FL+ + + +D A+L+++ DGV AQTR L+ G P + Sbjct: 66 ENTKV-NIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTI 124 Query: 108 TVALTKADRVDEARVDEVERQVKEVLR 134 + K D+ + V + +KE L Sbjct: 125 -FFINKIDQNG-IDLSTVYQDIKEKLS 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 64.5 bits (157), Expect = 2e-13 Identities = 56/314 (17%), Positives = 103/314 (32%), Gaps = 82/314 (26%) Query: 66 ITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVR------------YQARVD--RLQA--- 108 I P IV E+ K + ++KG+VL KL + QAR++ R Q Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 109 ------------------------DLMTATHNIK----TLRAQLTEAQANTTQVSAERDR 140 +++ T IK T + Q + + N + AER Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 141 LFKNYQRY----------LKGSQAAVNPFS---------ERDIDDARQNF---LAQDALV 178 + RY L + ++ + E +A +Q + Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 179 KGSVAE----QAQIQSQLDSMVNGE----QSQIVSLRAQLTEAKYNLEQTVIRAPSNGYV 230 + + + + + + I L +L + + + +VIRAP + V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 231 TQVLIR-PGTYAAALPLRPVMVFIPEQKRQIV-AQFRQNSLLRLKPGDDAEVVFNALPGQ 288 Q+ + G +MV +PE V A + + + G +A + A P Sbjct: 339 QQLKVHTEGGVVT--TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 289 VFH---GKLTSILP 299 + GK+ +I Sbjct: 397 RYGYLVGKVKNINL 410
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 63.3 bits (154), Expect = 3e-14 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 1701 ESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGV-SMVSANGRWVYKLQ 1759 +L G+A+ A++ L Q G + S G Y ++A+A+GV S ++ + Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 1760 GSTNSQGEYSAALGAGIQW 1778 +T + G S G ++ Sbjct: 62 FNTYN-GGMSYGASVGYEF 79
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.020 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 13/87 (14%) Query: 8 MTVI---GAGSYGTALAITLARNGHEVVLWGHD---PEHIATLERDRCNAAFLPDVPFPD 61 M + AG G ++ L GH+VV G D + +L++ R P F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQF-- 56 Query: 62 TLHLESDLATALAASRNILVVVPSHVF 88 + DLA + VF Sbjct: 57 ---HKIDLADREGMTDLFASGHFERVF 80
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 240 bits (613), Expect = 2e-84 Identities = 87/153 (56%), Positives = 117/153 (76%), Gaps = 4/153 (2%) Query: 23 EQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRV 82 Q + QIQRIY KD+SFEAPN PH+FQ+DW+P++ DL T + Q+ DD+YEV L + Sbjct: 12 TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNI 71 Query: 83 TVTASLGEE--TAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSR 140 +V ++ AF+CEV+Q G+F+I+G+E QMAHCL + CPN+LFPYARE ++S+V+R Sbjct: 72 SVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNR 131 Query: 141 GTFPQLNLAPVNFDALFMNYL--QQQAGEGTEE 171 GTFP LNL+PVNFDALFM+YL Q+QA + TEE Sbjct: 132 GTFPALNLSPVNFDALFMDYLQRQEQAEQTTEE 164
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 36.2 bits (83), Expect = 2e-04 Identities = 51/223 (22%), Positives = 74/223 (33%), Gaps = 22/223 (9%) Query: 60 RAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNKQIDEMNASIAKLEQQKA 119 R + +++ R A K +EA RE T QL E A E+ KA Sbjct: 131 RLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKA 190 Query: 120 ---AQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLNQARQETIAQLKQ 176 AQ++ AAQ + GE + LS AR + L Sbjct: 191 VEIAQKKLSAAQSEVVKMDGEIKTLNSRLSS---------------SIHARDAEMKTLAG 235 Query: 177 TREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKKTLAGLESSIQQGQQQLSE 236 R E+A A+ +E + L + R++ AG +Q Q SE Sbjct: 236 KRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASE 295 Query: 237 LRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEATRK 279 R N R+ I + + A R A R + E K Sbjct: 296 TRIN--RINADITQIQKAIS--QVSNNRNAGIARVHEAEENLK 334
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (260), Expect = 7e-28 Identities = 77/348 (22%), Positives = 127/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLDI 47 +VTG AGFIG ++ K L + G ++ +DNL D +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>SECA#SecA protein signature. Length = 901 Score = 40.2 bits (94), Expect = 3e-05 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 18/129 (13%) Query: 244 NLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARVVAEIERDM-ALDVPMM 302 LS L+ F A+ L + L+N + A A R ++ M DV ++ Sbjct: 37 KLSDEELKGKTAEFRAR-LEKGEVLENLIPEAF------AVVREASKRVFGMRHFDVQLL 89 Query: 303 ---RLVQGDV-----GSGKTLVAALAA-LRAIAHGKQVALMAPTELLAEQHANNFRNWFA 353 L + + G GKTL A L A L A+ GK V ++ + LA++ A N R F Sbjct: 90 GGMVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFE 148 Query: 354 PLGIEVGWL 362 LG+ VG Sbjct: 149 FLGLTVGIN 157
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 32.9 bits (75), Expect = 0.004 Identities = 23/164 (14%), Positives = 58/164 (35%), Gaps = 20/164 (12%) Query: 22 RQNRLLRFLLPRREYTTIVTIAGYLNVSEKTIQRDLRLLEQWL-GQWRINVEKRAGAGVM 80 + +L+ + I +A ++ + L + + ++KR M Sbjct: 45 SKCQLVVLFF-KTSSLPITEVAEKTGLTFLQLNHYCEELNAFFPDSLSMTIQKR-----M 98 Query: 81 LSAENIADLLHLDHLLVAECEEIDCVMNNARRVKIASQLLSETPNETSISKLSERYFISG 140 + H ++ + + ++ +++ + L+ + ++ + +F+S Sbjct: 99 I-------SCQFTHP--SKETYLYQLYASSNVLQLLAFLIKNGSHSRPLTDFARSHFLSN 149 Query: 141 ASIVNDLRVIESWLAPLGLSLIRSPSGTHIEGSEGQVRQAMALL 184 +S + L L L S I G E ++R +ALL Sbjct: 150 SSAYRMREALIPLLRNFELKL----SKNKIVGEEYRIRYLIALL 189
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 45.6 bits (108), Expect = 3e-07 Identities = 37/176 (21%), Positives = 68/176 (38%), Gaps = 5/176 (2%) Query: 39 QLRWWMLILFLMGVTVNYITRNSLGILAPELKDSLGITTEQYSWIVGGFQLAYTLFQPLC 98 Q+ W+ IL V + L + P++ + +W+ F L +++ + Sbjct: 14 QILIWLCILSFFSV----LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 99 GWLIDVIGLKIGFMICASLWGIACLLHAGAGSWIQLALLRFFMGGAEASATPA-NAKIIG 157 G L D +G+K + + ++ S+ L ++ F+ GA A+A PA ++ Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 158 EWFPKSERPVAAGWAGVGFSIGAMLAPPIIYFAHASFGWQGAFMFTGALAILWVFL 213 + PK R A G G ++G + P I W + I FL Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFL 185
>PF06580#Sensor histidine kinase Length = 349 Score = 203 bits (519), Expect = 4e-64 Identities = 56/214 (26%), Positives = 101/214 (47%), Gaps = 14/214 (6%) Query: 203 RKRVEIERSLHEAEFKALSYQINPHFLFNVLNTIGRLAFLEDAQRTETMVHDFSDMMRYL 262 + ++ EA+ AL QINPHF+FN LN I L LED + M+ S++MRY Sbjct: 149 IDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALI-LEDPTKAREMLTSLSELMRYS 207 Query: 263 LRKNSHGLITLRNEINYVNNYMSIQKVRMRDRFDYLCDIPEKYLDVVCPFLILQPLVENF 322 LR ++ ++L +E+ V++Y+ + ++ DR + I +DV P +++Q LVEN Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENG 267 Query: 323 FNYVVEPRDSNSHLLIRATDDGLNVIIEVTDNGDGIAPDTINRILSGDQKLQKGSIGINN 382 + + +L++ T D V +EV + G +T + G+ N Sbjct: 268 IKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK----------ESTGTGLQN 317 Query: 383 IKNRLKLLFGESYGLEIMSPNKPRMGTTIKLRFP 416 ++ RL++L+G +++ + P Sbjct: 318 VRERLQMLYGTEAQIKLSEKQG---KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 6e-12 Identities = 29/139 (20%), Positives = 53/139 (38%), Gaps = 3/139 (2%) Query: 3 TIVIVEDEPIELESLRQIISQCVENAAIHEASTGKKAIHLIDQLSQIDMILVDINIPLPN 62 TI++ +D+ L Q +S+ + S I D+++ D+ +P N Sbjct: 5 TILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMPDEN 61 Query: 63 GKQVIEYLKKKNSDTKIIVITANDDFDIVRSMYNLKVDDYLLKPVKKCILTDTIKKTLAF 122 ++ +KK D ++V++A + F DYL KP L I + LA Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 123 DEGENEKSRALKQKVFAMI 141 + K Q ++ Sbjct: 122 PKRRPSKLEDDSQDGMPLV 140
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.4 bits (177), Expect = 4e-18 Identities = 33/63 (52%), Positives = 41/63 (65%) Query: 10 RHTKFAAEETRKQILDVAEFCFCETGFSKTTLEMIAARAGCTRGAIYWYFNEKKDLLRQV 69 R TK A+ETR+ ILDVA F + G S T+L IA AG TRGAIYW+F +K DL ++ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 IER 72 E Sbjct: 63 WEL 65
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 411 bits (1057), Expect = e-137 Identities = 202/339 (59%), Positives = 270/339 (79%), Gaps = 1/339 (0%) Query: 1 MIQARNQLLAEAAKSPA-LNMVRPNGMNDEPQFQILIDDEKVQAFKLSMSDVDNIMSAAW 59 + QARNQLL AA+ PA L VRPNG+ D QF++ +D EK QA +S+SD++ +S A Sbjct: 694 LTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTAL 753 Query: 60 GSMYVNDFNDRGRVKKVYIQGEPGSRISPQDFDKWYVRNSDGDMVSFASFATGKWIYGSP 119 G YVNDF DRGRVKK+Y+Q + R+ P+D DK YVR+++G+MV F++F T W+YGSP Sbjct: 754 GGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSP 813 Query: 120 KLEQYNGISAVEILGEPAPGYSSGDAMKAIEDIAARLPEGFHISWTGLSFEERLSGSQAP 179 +LE+YNG+ ++EI GE APG SSGDAM +E++A++LP G WTG+S++ERLSG+QAP Sbjct: 814 RLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAP 873 Query: 180 ALYALSLLIVFLCLAALYESWSIPFSVMLVVPLGVLGAVCATLLRGLGNDVFFQVGLLTT 239 AL A+S ++VFLCLAALYESWSIP SVMLVVPLG++G + A L NDV+F VGLLTT Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 240 IGLSAKNAILIVEFARELHEKEGLSIKEAAVEAARVRLRPIIMTSLAFVMGVIPLAVSTG 299 IGLSAKNAILIVEFA++L EKEG + EA + A R+RLRPI+MTSLAF++GV+PLA+S G Sbjct: 934 IGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNG 993 Query: 300 ASSGSKHAIGTGVVGGMITATILAIFYIPLFYMLIAGFF 338 A SG+++A+G GV+GGM++AT+LAIF++P+F+++I F Sbjct: 994 AGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCF 1032 Score = 77.2 bits (190), Expect = 1e-17 Identities = 64/322 (19%), Positives = 125/322 (38%), Gaps = 21/322 (6%) Query: 29 EPQFQILIDDEKVQAFKLSMSDVDNIMSAA----WGSMYVNDFNDRGRVKKVYIQGEPGS 84 + +I +D + + +KL+ DV N + G+ I + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQ-TR 239 Query: 85 RISPQDFDKWYVR-NSDGDMVSFASFAT---GKWIYGSPKLEQYNGISAVEILGEPAPGY 140 +P++F K +R NSDG +V A G Y + + NG A + + A G Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV--IARINGKPAAGLGIKLATGA 297 Query: 141 SSGDAMKAI----EDIAARLPEGFHISW---TGLSFEERLSGSQAPALYALSLLIVFLCL 193 ++ D KAI ++ P+G + + T + + A+ ++VFL + Sbjct: 298 NALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI--MLVFLVM 355 Query: 194 AALYESWSIPFSVMLVVPLGVLGAVCATLLRGLGNDVFFQVGLLTTIGLSAKNAILIVEF 253 ++ + VP+ +LG G + G++ IGL +AI++VE Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 254 ARELHEKEGLSIKEAAVEAARVRLRPIIMTSLAFVMGVIPLAVSTGASSGSKHAIGTGVV 313 + ++ L KEA ++ ++ ++ IP+A G++ +V Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 314 GGMITATILAIFYIP-LFYMLI 334 M + ++A+ P L L+ Sbjct: 476 SAMALSVLVALILTPALCATLL 497
>PF06704#DspF/AvrF protein Length = 129 Score = 25.2 bits (55), Expect = 0.047 Identities = 20/85 (23%), Positives = 39/85 (45%), Gaps = 6/85 (7%) Query: 28 RTTQEKIAIVQQSFEPGMTVSLVARQHGVAASQLFLWRKQYQEGSLTAVAA-GEQVVPAS 86 + + + +S + SL A Q+GV A L+ Q E ++ + E V+ Sbjct: 2 NNSPTDFSRLIKSLGAQLGTSLTA-QNGVCA----LYDSQDNEAAVIEMPDHSEMVIFHC 56 Query: 87 ELAAAMKQIKELQRLLNKTPDVSRL 111 + + + +LQ+LL+ DV+R+ Sbjct: 57 RVGRSPDRAADLQKLLSLNFDVARM 81
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.049 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.002 Identities = 11/71 (15%), Positives = 30/71 (42%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVAEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 601 bits (1550), Expect = 0.0 Identities = 206/478 (43%), Positives = 299/478 (62%), Gaps = 11/478 (2%) Query: 21 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 80 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 81 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 140 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 141 HYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 200 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 201 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 260 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 261 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVLEGKFREDLFHR 320 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 321 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 380 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 381 ENTCRWLTVMAAGQEVLIQDLPGELFESNVPESTSHMQPDSWATLLAQWADRALRS---- 436 EN R LT + + + + EL S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 437 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 489 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.018 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 81 T +++ G +G GK +AR K N PF+ + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 41.2 bits (96), Expect = 5e-06 Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLVQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVARV 232 T E++ Q T T+Q V + + + A+TQ + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 357 bits (916), Expect = e-127 Identities = 171/262 (65%), Positives = 204/262 (77%), Gaps = 6/262 (2%) Query: 30 WLHQSLNVIGRTDSRFGPRLTNDLYPEYTVAGRKDWFDFYGYVDLPKFFGVGSHYDVGIW 89 W HQS+NV+G +RFGP++ ND Y EY +KDWFDFYGY+D P FFG G+ GIW Sbjct: 34 WWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYIDAPVFFG-GNSTAKGIW 92 Query: 90 DEGSPLFTEIEPRFSIDKLTGLNLAFGPFKEWFIANNYVYDMGDNQSSRQSTWYMGLGTD 149 ++GSPLF EIEPRFSIDKLT +L+FGPFKEW+ ANNY+YDMG N S QSTWYMGLGTD Sbjct: 93 NKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNDSQEQSTWYMGLGTD 152 Query: 150 IDTGLPIKLSANIYAKYQWQNYGAANENEWDGYRFKIKYSIPLTNLFGGRLVYNSFTNFD 209 IDTGLP+ LS N+YAKYQWQNYGA+NENEWDGYRFK+KY +PLT+L+GG L Y FTNFD Sbjct: 153 IDTGLPMSLSLNVYAKYQWQNYGASNENEWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFD 212 Query: 210 FGSDLADKSHNN-----KRTSNAIASSHILSLLYEHWKFAFTLRYFHNGGQWNAGEKVNF 264 +GSDL D + + RTSN+IASSHIL+L Y HW ++ RYFHNGGQW K+NF Sbjct: 213 WGSDLGDDNFYDLNGKHARTSNSIASSHILALNYAHWHYSIVARYFHNGGQWADDAKLNF 272 Query: 265 GDGPFELKNTGWGTYTTIGYQF 286 GDGPF +++TGWG Y +GY F Sbjct: 273 GDGPFSVRSTGWGGYFVVGYNF 294
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 443 bits (1142), Expect = e-155 Identities = 158/485 (32%), Positives = 230/485 (47%), Gaps = 48/485 (9%) Query: 6 SEITIVYIEDSDDVRFACEQTLTLAGYRVISCCDAEHSIPLIQSQANIIILTDVRLPGIS 65 + TI+ +D +R Q L+ AGY V +A I + +++TDV +P + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GLELLSYINEMDSKIPVILITGHGDVEMAVDAMRNGAFDFIEKPSSSDKLLSIIARAVEK 125 +LL I + +PV++++ A+ A GA+D++ KP +L+ II RA+ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 126 RRLVLENQQLLANLQQENGPVLIGRSPQMQQLRKMILNVADTGADVLIYGETGCGKEVVA 185 + + + ++G L+GRS MQ++ +++ + T ++I GE+G GKE+VA Sbjct: 122 PKRRPSKLEDDS----QDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 186 RMLHHWSTRRQGQFVALNCAGLPETLFESEIFGHEAGAFTGAVKKRIGKIEHANGGTLFL 245 R LH + RR G FVA+N A +P L ESE+FGHE GAFTGA + G+ E A GGTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 246 DEIEGMPSGMQVKLLRVLQERTIERLGANQLIPVNCRVIAATKEDLLRRSEEHLFRLDLY 305 DEI MP Q +LLRVLQ+ +G I + R++AAT +DL + + LFR DLY Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 306 YRLNVVSLNIPPLRQRREDIPELFYWFASQAAQKYNRPLPDISPMLLAWLQSQSWPGNVR 365 YRLNVV L +PPLR R EDIP+L F QA K + L +++ WPGNVR Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 366 ELKHNAERFVL----------------GLLTHHQPVPMTQQEESGLTAC----------- 398 EL++ R P+ L+ Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 399 ----------------IDAFEKKLIEDMLRQTEGQVSLTARLLQLPRKTLYDKLNKHQIQ 442 + E LI L T G A LL L R TL K+ + + Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476 Query: 443 PQVYR 447 Sbjct: 477 VYRSS 481
>PERTACTIN#Pertactin signature. Length = 922 Score = 27.0 bits (59), Expect = 0.048 Identities = 15/50 (30%), Positives = 19/50 (38%), Gaps = 4/50 (8%) Query: 119 GGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSG----GAQSRPQQSAPAAP 164 G APAGG + GG GG + + G + QS AP Sbjct: 261 GDAPAGGAVPGGAVPGGAVPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAP 310
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.019 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 18 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 49 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.9 bits (67), Expect = 0.007 Identities = 6/21 (28%), Positives = 12/21 (57%) Query: 179 FGNLDDPSSEISQLLRQKPTY 199 GNL++P+ ++ L+ P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 50 HLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAG 109 L L+ +G I + + N I+++ V R VG+ LL A E A++ Sbjct: 68 FLYYLENNCIGRIKIRSNW-----NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 110 AEMTELSTNVKRHDAHRFYLREGY 133 L T A FY + + Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.013 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 89 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 90 TTVGWVSQFL 99 V F Sbjct: 656 ADAEAVKAFF 665
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 2e-15 Identities = 31/109 (28%), Positives = 51/109 (46%), Gaps = 4/109 (3%) Query: 4 VLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKEN 63 +L+ DDDA + + + +++ G+ S I + DL++ D+ M EN Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPVLHNARCKSDVIVISSAADAVTIKDSLHYGVVDYLIKPFQASR 112 DLLP + AR V+V+S+ +T + G DYL KPF + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 8e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.4 bits (58), Expect = 0.012 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 32 LAIIEHTDVDESLKGQGIGKQLVAKVVE 59 A+IE V + + +G+G L+ K +E Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIE 116
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.028 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWSWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 8e-05 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 391 PLDEKQLAALNTEIDNIVTLPELNNLS-----IIYQIKAVSALVKGKTDESYQAINTGID 445 ++ A+ + + T+ LN +S +Y + A + GK +++++ Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSL-AFNQYQSGKYEDAHKVFQALCV 64 Query: 446 LEMSWLNYVL-LGKVYEMKGMNREAADAYLTAFNLRP 481 L+ + L LG + G A +Y + Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101
>PF03627#PapG Length = 336 Score = 601 bits (1550), Expect = 0.0 Identities = 333/336 (99%), Positives = 334/336 (99%) Query: 1 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT 60 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT Sbjct: 1 MKKWFPALLFSLCVSGESSAWNNIVFYSLGNVNSYQGGNVVITQRPQFITSWRPGIATVT 60 Query: 61 WNQCNGPEFADGSWAYYREYIAWVVFPKKVMTQNGYPLFIEVHNKGSWSEENTGDNDSYF 120 WNQCNGP FADGSWAYYREYIAWVVFPKKVMT+NGYPLFIEVHNKGSWSEENTGDNDSYF Sbjct: 61 WNQCNGPGFADGSWAYYREYIAWVVFPKKVMTKNGYPLFIEVHNKGSWSEENTGDNDSYF 120 Query: 121 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSVKIPYTSGMQ 180 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSV IPYTSGMQ Sbjct: 121 FLKGYKWDERAFDAGNLCQKPGETTRLTEKFDDIIFKVALPADLPLGDYSVTIPYTSGMQ 180 Query: 181 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY 240 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY Sbjct: 181 RHFASYLGARFKIPYNVAKTLPRENEMLFLFKNIGGCRPSAQSLEIKHGDLSINSANNHY 240 Query: 241 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY 300 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY Sbjct: 241 AAQTLSVSCDVPANIRFMLLRNTTPTYSHGKKFSVGLGHGWDSIVSVNGVDTGETTMRWY 300 Query: 301 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP 336 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP Sbjct: 301 KAGTQNLTIGSRLYGESSKIQPGVLSGSATLLMILP 336
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 742 bits (1918), Expect = 0.0 Identities = 243/882 (27%), Positives = 362/882 (41%), Gaps = 67/882 (7%) Query: 5 MRGMKDRI-PFAVNNITCVILLSLFCNAASAVEFNTDVLDAADKKNIDFTRFSEAGYVLP 63 + K R+ F V + +++ + FN L + D +RF + P Sbjct: 16 LHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPP 75 Query: 64 GQYLLDVIVNGQSISPASLQISFVEPQSSGDKAEKKLPQACLTSDMVRLMGLTAESLDKV 123 G Y +D+ +N + A+ ++F S CLT + MGL S+ + Sbjct: 76 GTYRVDIYLNNGYM--ATRDVTFNTGDSEQGI------VPCLTRAQLASMGLNTASVSGM 127 Query: 124 VYWHDGQCADF-HGLPGVDIRPDTGAGVLRINMPQAWLEYSDATWLPPSRWDDGIPGLML 182 D C + + D G L + +PQA++ ++PP WD GI +L Sbjct: 128 NLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLL 187 Query: 183 DYNLNGTVSRNYQGGDSHQFSYNGTVGGNLGPWRLRADYQGSQEQSRYNGEKTTNRNFTW 242 +YN +G +N GG+SH N G N+G WRLR + S S + + + Sbjct: 188 NYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSS--DSSSGSKNKWQH 245 Query: 243 SRFYLFRAIPRWRANLTLGENNINSDIFRSWSYTGASLESDDRMLPPRLRGYAPQITGIA 302 +L R I R+ LTLG+ DIF ++ GA L SDD MLP RG+AP I GIA Sbjct: 246 INTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIA 305 Query: 303 ETNARVVVSQQGRVLYDSMVPAGPFSIQDLD-SSVRGRLDVEVIEQNGRKKTFQVDTASV 361 A+V + Q G +Y+S VP GPF+I D+ + G L V + E +G + F V +SV Sbjct: 306 RGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSV 365 Query: 362 PYLTRPGQVRYKLVSGRSRGYGHETEGPVFATGEASWGLSNQWSLYGGAVLAGDYNALAA 421 P L R G RY + +G R + E P F GL W++YGG LA Y A Sbjct: 366 PLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNF 425 Query: 422 GAGWDLGVPGTLSADITQSVARIEGERTFQGKSWRLSYSKRFDNADADITFAGYRFSERN 481 G G ++G G LS D+TQ+ + + + G+S R Y+K + + +I GYR+S Sbjct: 426 GIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 482 YMTMEQYLNARYR--------------------NDYSSREKEMYTVTLNKNVADWNTSFN 521 Y +R + + ++ +T+ + + + + Sbjct: 486 YFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS-TLY 544 Query: 522 LQYSRQTYWDIRKTD-YYTVSVNRYFNVFGLQGVAVGLSASRSKYLGRD--NDSAYLRIS 578 L S QTYW D + +N F + LS S +K + + L ++ Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFE-----DINWTLSYSLTKNAWQKGRDQMLALNVN 599 Query: 579 VPLGT------------GTASYSGSMSND-RYVNMAGYTDM-FNDGLDSYSLNAGLNSGG 624 +P +ASYS S + R N+AG D SYS+ G GG Sbjct: 600 IPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGG 659 Query: 625 GLTSQRQINAYYSHRSPLANLSANIASLQKGYTSFGVSASGGATITGKGAALHAGGMSGG 684 S A ++R N + S SGG G L G Sbjct: 660 DGNSGSTGYATLNYRGGYGNANIG-YSHSDDIKQLYYGVSGGVLAHANGVTL--GQPLND 716 Query: 685 TRLLVDTDGVGGVPVDGGQVV-TNRWGTGVVTDISSYYRNTTSVDLKRLPDDVEATRSVV 743 T +LV G V+ V T+ G V+ + Y N ++D L D+V+ +V Sbjct: 717 TVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVA 776 Query: 744 ESALTEGAIGYRKFSVLKGKRLFAILRLADGSQPPFGASVTSEKGRELGMVADEGLAWLS 803 T GAI +F G +L L + PFGA VTSE + G+VAD G +LS Sbjct: 777 NVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLS 835 Query: 804 GVTPGETLSVNW--DGKIQCQVNVPETAISDQQLL----LPC 839 G+ + V W + C N S QQLL C Sbjct: 836 GMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 66/387 (17%), Positives = 130/387 (33%), Gaps = 39/387 (10%) Query: 52 TPYLKEQLDLSATQI---GVLSSCMLIAYGISKGVMSSLADKASPKVFMACGLVLCAIVN 108 P L L S G+L + + V+ +L+D+ + + L A+ Sbjct: 28 LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDY 87 Query: 109 VGLGFSTAFWIFAALVILNGLFQGMGVGPSFITIANWFPRRERGRVGAFWNISHNIGGGI 168 + + W+ I+ G+ G IA+ ER R F +S G G+ Sbjct: 88 AIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIADITDGDERAR--HFGFMSACFGFGM 144 Query: 169 VA-PIVGAAFALLGSEHWQSASYIVPACVAIVFAVIVLILGKGSPHQEGLPSLEEMMPEE 227 VA P++G A + A + + + L +PE Sbjct: 145 VAGPVLGGLMGGFSPH----APFFAAAALNGLNFLTGCFL----------------LPE- 183 Query: 228 KVVLNTRQTVKAPENMSAFQIFCTYVLRNKNAWYVSLVDVFVYMVRFGMISWLPIYLLTV 287 + + + P A ++ +L+ VF M G + + Sbjct: 184 -----SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 288 KHFSKEQMSVAFLFFEWA---AIPSTLLAGWLSDKLFKGRRMPLAMICMALIFICLIGYW 344 F + ++ + ++ ++ G ++ +L + R + L MI +I L Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 345 KSESLFMVTIFAAIVGCLIYVPQFLASVQTMEIVPSFAVGSAVGLRGFMSYIFGASLGTS 404 + F + + A G + Q + S Q E GS L ++ I G L T+ Sbjct: 299 RGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTS-LTSIVGPLLFTA 357 Query: 405 LFGIMVDHIGWHGGFYLLGCGIICCII 431 ++ + W+G ++ G + + Sbjct: 358 IYAASITT--WNGWAWIAGAALYLLCL 382
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 240 bits (615), Expect = 7e-77 Identities = 113/479 (23%), Positives = 191/479 (39%), Gaps = 83/479 (17%) Query: 10 SILLIDDDADVLDAYTQLLEQSGYRVFACNNPFEAQAWIQPDWPGIVLSDVCMPGCSGID 69 +IL+ DDDA + Q L ++GY V +N WI +V++DV MP + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 70 LMMLFHQDDQQLPILLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLSLVEEALRQRQS 129 L+ + LP+L+++ A+ A +KGA+D+L KP D +L+ ++ AL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 130 IIARRQYCQQTLQVELIGRSEWINQYRRRLQQLSETDIAVWLYGAPGTGRMTGARYLHQF 189 ++ + Q L+GRS + + R L +L +TD+ + + G GTG+ AR LH + Sbjct: 125 RPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 190 GRNAQGEFVYRELTPDNAPQLND------------------------FIALAQGGTLVLS 225 G+ G FV N + A+GGTL L Sbjct: 184 GKRRNGPFV-----AINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 226 HPEHLTREQQYHLVQ-LQSQEHRP----------FRLIGIGDTSLVELAASNHIIAELYY 274 + + Q L++ LQ E+ R++ + L + +LYY Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 275 CFAMTQIACLPLTQRPDDIEPLFRHYLCKACQRLNHPVPEVGKEMLKEMMRRMWPNNVRE 334 + + PL R +DI L RH++ +A + V +E L+ M WP NVRE Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 335 LANAAE--------------------------------LFTVGVLPLAE---------TA 353 L N G L +++ A Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 354 NPLMHVGTPTPLDRRVEDAERQIITEALNIHQGRINEVAEYLQIPRKKLYLRMKKYGLS 412 + + DR + + E +I AL +G + A+ L + R L ++++ G+S Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.9 bits (111), Expect = 1e-08 Identities = 30/199 (15%), Positives = 57/199 (28%), Gaps = 14/199 (7%) Query: 1 MGKTEENSVQ-REDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYD 59 KT++ + + R+ +L AL+L QG+++T+L +A+ + + DK + + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 60 ALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIAACTFYPDPG 119 I + L + E + F+ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLEST--VTEERRRLLMEIIFHKCEF 119 Query: 120 H----PIHQLADQQKSAAYDFTHELLTT-------LEVDDPAMVAKQMELVLEGCLSRML 168 + Q +YD + L A M + G + L Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 169 VNRSQADVDTAHRLAEDIL 187 D+ R IL Sbjct: 180 FAPQSFDLKKEARDYVAIL 198
>SECA#SecA protein signature. Length = 901 Score = 31.8 bits (72), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLDDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.027 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 179 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 232 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 32.4 bits (74), Expect = 0.001 Identities = 22/122 (18%), Positives = 47/122 (38%), Gaps = 12/122 (9%) Query: 85 VNPSLINEVAEEIARLENLITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKA 144 + + I +V+ EI +L A E+ L +D E ++ A I F + V+ Sbjct: 29 IEKTSITDVSTEIEKLT---AALEKSKEELRAIKDQTEASMGADKAEI--FAAHLLVLDD 83 Query: 145 TEAMQRAQQAVTTSTVGASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDE 204 E + + + + A ++ ++ +D E+ AD RD+ + Sbjct: 84 PELVDGIKGKIENEQMNAEYALKEVSD-------MFVSMFESMDNEYMKERAADIRDVSK 136 Query: 205 KL 206 ++ Sbjct: 137 RV 138
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.032 Identities = 6/19 (31%), Positives = 7/19 (36%), Gaps = 2/19 (10%) Query: 118 FNGDVQI--ELTGYWTWEQ 134 F G + L W EQ Sbjct: 62 FKGQEDLGNGLKAIWQVEQ 80
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 1098 bits (2842), Expect = 0.0 Identities = 877/878 (99%), Positives = 877/878 (99%) Query: 1 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQA 60 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQA Sbjct: 1 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQA 60 Query: 61 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN Sbjct: 61 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120 Query: 121 TASVSGMNLLADDACVPLTSMIHDATAHLDVGQQRLNLTIPQAFMSNRARGYIPPELWDP 180 TASVSGMNLLADDACVPLTSMIHDATA LDVGQQRLNLTIPQAFMSNRARGYIPPELWDP Sbjct: 121 TASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDP 180 Query: 181 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSK 240 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSK Sbjct: 181 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSK 240 Query: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV Sbjct: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 Query: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV Sbjct: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 Query: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY Sbjct: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 Query: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR Sbjct: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480 Query: 481 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT 540 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT Sbjct: 481 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT 540 Query: 541 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI Sbjct: 541 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600 Query: 601 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD 660 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD Sbjct: 601 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD 660 Query: 661 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL 720 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL Sbjct: 661 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL 720 Query: 721 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP 780 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP Sbjct: 721 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP 780 Query: 781 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA 840 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA Sbjct: 781 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA 840 Query: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR Sbjct: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.5 bits (82), Expect = 4e-04 Identities = 30/129 (23%), Positives = 48/129 (37%), Gaps = 33/129 (25%) Query: 26 CDVLIANGKIIAVASNIPSDIVPDCT--------VVDLSGQILCPGFIDQHVHLIGG--- 74 D+ + +G+I A+ D+ P T V+ G+I+ G +D H+H I Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQI 145 Query: 75 ------------GGEAGP------TTRTP-EVALSRLTEA--GITSVVGLLGTDSISRHP 113 GG GP TT TP ++R+ EA + G + S P Sbjct: 146 EEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNAS-LP 204 Query: 114 ESLLAKTRA 122 +L+ Sbjct: 205 GALVEMVLG 213
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.027 Identities = 58/312 (18%), Positives = 106/312 (33%), Gaps = 16/312 (5%) Query: 82 RPFLLASALASGLLILAMAWLPPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLA 141 RP LL S + + MA P ++ + R++AG+ A + G+ + Sbjct: 73 RPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARH 132 Query: 142 ALFSGVGIGIALSNEYVLAGLHFDLSSQTLWQGAGALSGMMLIALTLLMP-SKKHAIAPM 200 F G + VL GL S + A AL+G+ + L+P S K P+ Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPL 192 Query: 201 PLAKTEQQIMSWW---------LLAILYGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWT 251 W L+A+ + + G + A ++ T + + Sbjct: 193 RREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGI-S 251 Query: 252 LVGLSIVPGCFGWLWA---AKRWGALPCLTANLLVQAIS-VLLTLASDSPLLLIISSLGF 307 L I+ + A R G L ++ +LL A+ + I L Sbjct: 252 LAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVL-L 310 Query: 308 GGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLGNGTSALASATL 367 +G +L ++RQ+ L G + + + I+GP L + + + + Sbjct: 311 ASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWA 370 Query: 368 CGAAALFIAALI 379 A A + Sbjct: 371 WIAGAALYLLCL 382
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 29.1 bits (65), Expect = 0.026 Identities = 10/45 (22%), Positives = 17/45 (37%) Query: 54 LFVIVAVCTFFVQSCARKSNHAASFQNYHATIDGKEIAGITNNIS 98 +++ + + +CA S Q IA IT NI+ Sbjct: 6 TLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIA 50
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 482 bits (1243), Expect = e-177 Identities = 250/262 (95%), Positives = 253/262 (96%) Query: 1 MAYRSAPLYEDVIWRTHLQPQDAGLAQAVRATIAEHREHLLEFIRLDEPAPLNAMTLAQW 60 MAYRSAPLYEDVIWRTHLQPQD LAQAVRATIA+HREHLLEFIRLDEPAPLNAMTLAQW Sbjct: 1 MAYRSAPLYEDVIWRTHLQPQDPTLAQAVRATIAKHREHLLEFIRLDEPAPLNAMTLAQW 60 Query: 61 SSPNALSSLLAVYSDHIYRNQPLMIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDV 120 SSPN LSSLLAVYSDHIYRNQP+MIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDV Sbjct: 61 SSPNVLSSLLAVYSDHIYRNQPMMIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDV 120 Query: 121 SPEHVHVEFHETGRAACFWVDVCEDKNATLHSPQQRMETLISQALVPVVQALEATGEING 180 SPEH H EFHETGR ACFWVDVCEDKNAT HSPQ RMETLISQALVPVVQALEATGEING Sbjct: 121 SPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQHRMETLISQALVPVVQALEATGEING 180 Query: 181 KLIWSNTGYLINWYLTEMKQLLGEATVESLRYALFFEKTLTTGEDNPLWRTVVLRDGLLV 240 KLIWSNTGYLINWYLTEMKQLLGEATVESLR+ALFFEKTLT GEDNPLWRTVVLRDGLLV Sbjct: 181 KLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLTNGEDNPLWRTVVLRDGLLV 240 Query: 241 RRTCCQRYRLPDVQQCGDCTLK 262 RRTCCQRYRLPDVQQCGDCTLK Sbjct: 241 RRTCCQRYRLPDVQQCGDCTLK 262
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 54.6 bits (131), Expect = 4e-12 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 62 DEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFN 121 A + +IAV DY+++G+G ALL I+ ++ L LE + N +A Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 122 EATIRRNYYPTTDG-REDAI 140 + Y E AI Sbjct: 148 IGAVDTMLYSNFPTANEIAI 167
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.022 Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.5 bits (235), Expect = 1e-24 Identities = 32/149 (21%), Positives = 61/149 (40%), Gaps = 9/149 (6%) Query: 4 RILVVEDEVPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+ IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.043 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%) Query: 60 ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119 E P+ E + ++G+ A + +Y RL D +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.002 Identities = 33/144 (22%), Positives = 67/144 (46%), Gaps = 12/144 (8%) Query: 195 KQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQK 254 ++ + L A QV R +++ ++ S+ +Q++A + Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK---KQLEAEHQ 333 Query: 255 ELGEMDDAPD-ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDW 312 +L E + + ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D Sbjct: 334 KLEEQNKISEASRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390 Query: 313 MVQVPWNARSKVKKDLRQAQEILD 336 + A+ +V+K L +A L Sbjct: 391 SRE----AKKQVEKALEEANSKLA 410
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 3e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 27.1 bits (60), Expect = 0.021 Identities = 24/138 (17%), Positives = 41/138 (29%), Gaps = 20/138 (14%) Query: 1 MQTQIKVRGYHLDVYQHVNNARYL-------EFLEEARWHGLENSDSFHWMTAH------ 47 +Q I + Y N Y E++ + N FH + Sbjct: 361 LQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILR 420 Query: 48 ------NIAFVVVN-ININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVA 100 + FV N IN + + + + Q+ L+P+ + Sbjct: 421 NIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITH 480 Query: 101 DALITFVCIDLKTQKALA 118 LI FV +L A+A Sbjct: 481 SQLIPFVHHELTKGIAVA 498
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.019 Identities = 12/64 (18%), Positives = 24/64 (37%), Gaps = 10/64 (15%) Query: 197 LTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGN----------AMPQLRAELPH 246 TVL Q L + D +A + + ++ + +P+++ P Sbjct: 16 RTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPD 75 Query: 247 LPVI 250 LPV+ Sbjct: 76 LPVL 79
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 469 bits (1207), Expect = e-171 Identities = 272/276 (98%), Positives = 275/276 (99%) Query: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS Sbjct: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 Query: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDRDWMDSSNPGTWTDESR 120 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVD+DWMDSSNPGTWTDESR Sbjct: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 Query: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI Sbjct: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 Query: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEAFDNDEHYDPGKRIT 240 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVE+ DNDEHYDPGKRIT Sbjct: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT 240 Query: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYIEGAWNRV 276 YRSKVKDQNYYSVAVNAGYYVTPNAKVY+EGAWNRV Sbjct: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV 276
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 29/184 (15%), Positives = 67/184 (36%), Gaps = 34/184 (18%) Query: 306 EELTRMAKMVSDML-FLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDR-GVELRFV 363 + M +S+++ + + N + + LADE+ V + + LA + L+F Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVS------LADELTVVDSYLQ-LASIQFEDRLQFE 243 Query: 364 GDECQVAGDPLMLRRALSNLLSNALRY----TPTGETIVVRCQTVDHLVQVTVENPGTPI 419 D + + L+ N +++ P G I+++ + V + VEN G+ Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 420 APEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVK---SIVVAHKGTVAVTSDVRGTRFVI 476 E +G GL V+ ++ + + ++ ++ Sbjct: 304 LKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 477 ILPA 480 ++P Sbjct: 346 LIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.0 bits (91), Expect = 3e-05 Identities = 25/189 (13%), Positives = 60/189 (31%), Gaps = 13/189 (6%) Query: 254 QAQTVNSDSLQSVKLPA-GLPSQILLQRPDIMEAEHALM-----AANANIGAARAAFFPS 307 + +S + +K + +I+++ + + L+ A A+ ++ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS----- 141 Query: 308 ISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYE 367 SL + + + + P F + L + + ++Q Sbjct: 142 -SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 368 QKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARTLYQHGAVSYLEVLDAER 427 QK Q + A R ++ +I+ + + L +L A++ VL+ E Sbjct: 201 QKYQ-KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 428 SLFATRQTL 436 L Sbjct: 260 KYVEAVNEL 268
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 599 bits (1546), Expect = 0.0 Identities = 198/1048 (18%), Positives = 415/1048 (39%), Gaps = 90/1048 (8%) Query: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V + +YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAELGP-DATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVA 178 LP V + + + ++ V + D+ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELA------EAEYMVR 232 G ++ +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIAELNGEGEVAGGVVILR 292 A + ++F + L+ + +G V L+DVA+V++G E IA +NG+ AG + L Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLA 294 Query: 293 SGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVV 352 +G NA + A+K KL L+ P+G++++ YD + + +I + L E ++V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 CALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIE 412 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 NAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPALFISL------------------ 454 N + + E + +AT + ++ Q V A+FI + Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 455 -------LIITLSFIPI-----------------------------FTLEGQEGRLFGPL 478 +++ L P ++ + L Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKIL 534 Query: 479 AFTKTYAMAGA---ALLAIVVIPILMGYWIRGKEGDLLYMPSTLPGISAAEAASMLQKTD 535 T Y + A A + ++ + + + +G L M G + +L + Sbjct: 535 GSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVT 594 Query: 536 KLIM--SVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQDQW-RPGMTMDKIIEELD 592 + V VF G + + + LKP ++ + + +I Sbjct: 595 DYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 593 NTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADI-DTMAEQIEEVARTVPG 651 + + + +++ + I +G + + + A+ Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 652 VASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGETVEGIARYPIN 711 + S LE +E+++EKA G++++D+ +++A+GG V + ++ + Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 712 LRYPQSWRDSPQALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENARPTSWIYIDAR 771 ++ +R P+ + +L + + + + + G L+ N P+ I +A Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 772 DRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMTLMIIFVLLYL 831 L + +A K L G ++G + ++ +V ++ +++F+ L Sbjct: 832 PGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 832 AFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLR 891 + + ++ VP +VG + V G + G++A+ ++++ + + Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 892 HAIEAEPSLNNPQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVM 951 +E E + + EA +R+RP MT I G+LP+ GAGS Sbjct: 950 DLMEKE----------GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999 Query: 952 SRIAAPMIGGMITAPLLSLFIIPAAYKL 979 + + ++GGM++A LL++F +P + + Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.2 bits (102), Expect = 8e-07 Identities = 41/201 (20%), Positives = 64/201 (31%), Gaps = 34/201 (16%) Query: 23 AFLFLFAPTAFAAEQTVEAPSVDARAW----------ILMDYASGKVLAEGNADEKLDPA 72 + L A A P + I MD ASG+ L ADE+ Sbjct: 7 CIISLLATLPLAV-HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 73 SLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLN 132 S K++ V + A +L + + +P V D ++V +L Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGMTVGELC 119 Query: 133 KGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTT---FQTVHGLDAPGQF- 188 I S N A L V G + + +++G T ++T PG Sbjct: 120 AAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEALPGDAR 174 Query: 189 --STARDMA------LLGKAL 201 +T MA L + L Sbjct: 175 DTTTPASMAATLRKLLTSQRL 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.0 bits (96), Expect = 6e-06 Identities = 60/269 (22%), Positives = 109/269 (40%), Gaps = 23/269 (8%) Query: 81 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 140 +LG LSDR GRRPV+L + V + A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 141 QESFEEAVCIKITALMANVALIAPLLGPLVG---AAWIHVLPWEGMFVLFAALAAISFFG 197 + + + M+ + GP++G + P F AAL ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFLT 176 Query: 198 LQRAMPETATRIGEKLSLKELGRDYKLVLKNG-RFVAGALALGFVSLPLLAWIAQSP--I 254 +PE+ L + L G VA +A+ F ++ + Q P + Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAAL 232 Query: 255 IIITGEQLSSYEYGLLQVPI--FGAL--IAGNLLLARLTSRRTVRSLIIMGGWPIMIGLL 310 +I GE ++ + + + FG L +A ++ + +R R +++G G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 311 VAAAATVISSHAYLWMTAGLSIYAFGIGL 339 + A AT ++ + + + GIG+ Sbjct: 293 LLAFAT----RGWMAFPIMVLLASGGIGM 317
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.009 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 64 LVLLGPSGAGKSSLLRVL 81 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 28.7 bits (64), Expect = 0.023 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 9/54 (16%) Query: 2 RRVFWLVAAALLLAGCTGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADD 55 R+V LV ALL AG I K+G +LD Y ++ L HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.2 bits (185), Expect = 2e-17 Identities = 70/363 (19%), Positives = 123/363 (33%), Gaps = 65/363 (17%) Query: 22 MKVLVTGATSGLGRNAVEFLCQKGISVRA---------TGRNEAMGKLLEKMGAEFVPAD 72 MK LVTGA +G + + L + G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 73 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 125 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 126 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 185 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 186 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 243 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 244 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 289 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 290 MIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVLTLDEGIEKTAAW 349 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 350 LRD 352 RD Sbjct: 328 YRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.9 bits (135), Expect = 1e-10 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 29 RILVLGASGYIGQHLVRTLSQQGHQILA---------AARHVDRLAKLQLANVSCHKVDL 79 + LV GA+G+IG H+ + L + GHQ++ + RL L HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 80 SWPDNLPALLQD--IDTVYFLVH------SMGEGGDFIAQERQVALNVRDALREVPVKQL 131 + + + L + V+ H S+ + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 132 IFLSS 136 ++ SS Sbjct: 122 LYASS 126
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 4e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 353 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 401 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 37.2 bits (86), Expect = 1e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 350 bits (898), Expect = e-126 Identities = 231/232 (99%), Positives = 232/232 (100%) Query: 6 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 65 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 66 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGVFGNA 125 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQG+FGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 126 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 185 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 186 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 237 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 425 bits (1094), Expect = e-151 Identities = 156/363 (42%), Positives = 212/363 (58%), Gaps = 9/363 (2%) Query: 5 FLSALILLLVTTAVQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 64 F + L RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 65 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 124 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 125 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 184 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 185 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 240 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 241 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 300 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 301 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 360 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 361 AKL 363 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 510 bits (1315), Expect = 0.0 Identities = 311/313 (99%), Positives = 312/313 (99%) Query: 11 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 70 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 71 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEEPTPAAPMKFPLET 130 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEE TPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 131 VVRYQNQALSQLVQKAVPRNYDDSLPGNSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 190 VVRYQNQALSQLVQKAVPRNYDDSLPG+SKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 191 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 250 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 251 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 310 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 311 VSKTYSMNIDNLF 323 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 683 bits (1763), Expect = 0.0 Identities = 544/546 (99%), Positives = 546/546 (100%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSTADPSRTTVAYIDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPS+ADPSRTTVAY+DGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 361 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 46.2 bits (109), Expect = 8e-08 Identities = 42/226 (18%), Positives = 80/226 (35%), Gaps = 9/226 (3%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAGYKTETAPFSEADGDYVGGTESIKQQVDASRSMVIGHTGDKIFDSITSN 186 T NG + + DG E+I + +G G + + Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232 + T A + + TA DK Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 67.8 bits (165), Expect = 2e-13 Identities = 61/298 (20%), Positives = 93/298 (31%), Gaps = 54/298 (18%) Query: 513 PSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKSAPATPAAPAQPGLLS 572 P E+ + DVP P+ E A AP P APA P Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIA-----RVDEAPVPPPAPATP---- 1033 Query: 573 RFFGALKALFSGGEETKPSEQPTPKAEAKPERQQDRRKPRQNNRRDRNERRDPRSERTEG 632 SE AE + + K Q Sbjct: 1034 ------------------SETTETVAENSKQESKTVEKNEQ------------------- 1056 Query: 633 SDNREENRRNRRQAQQQTAETRESRQQAEV------TEKARTTDEQQTPRRERSRRRNDD 686 D E +NR A++ + + + Q EV T++ +TT+ ++T E+ + + Sbjct: 1057 -DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVE 1115 Query: 687 KRQAQQEVKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAVVAPVVE 746 + QEV + + QE + + + R +N K Q+ P E Sbjct: 1116 TEK-TQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 747 ETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQPEENNADNRDNGGMPRRSRRSPRH 804 + E V E+ T V P A QP N+ + RRS RS H Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232
>INTIMIN#Intimin signature. Length = 939 Score = 254 bits (650), Expect = 8e-78 Identities = 118/378 (31%), Positives = 194/378 (51%), Gaps = 21/378 (5%) Query: 79 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 138 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 139 DRYLTWSQLSLTQQDDGLVSNVGVGQRWARGSWLVGYNTFYDNLLDENLQRAGFGAEAWG 198 ++ L + Q+ D +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 199 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDR 256 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 257 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 316 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 317 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 376 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 377 RSRYGIRQLIWQGDTQILS-----LTPGAQANSEEGWTLIMPDWQNGEGASNHWRLSVVV 431 +S+YG+ +++W D+ + S G+Q S + + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 432 EDNQGQRVSSNEITLTLV 449 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.3 bits (185), Expect = 8e-18 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 29 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 88 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 89 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 145 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 52.9 bits (127), Expect = 2e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWVQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.012 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 260 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 316 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 317 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 372 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 373 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATDTAAALGFIS 413 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 29.8 bits (67), Expect = 0.043 Identities = 21/105 (20%), Positives = 36/105 (34%), Gaps = 2/105 (1%) Query: 526 PIDVELTESCLIENDELALSVIQQFSRLGAQVHLDDFGTGYSSLSQLARFPIDAIKLDQV 585 P+ V S I L S + FS + + ++ Q+ D + Sbjct: 425 PLVVVFVASNFINAHLLTDSFPRYFS--DKSIDFHSYYLLQDNVYQIPDLKPDLVITHSQ 482 Query: 586 FVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKEDAFLTK 630 + +H + V I L++Q + V+ K A LTK Sbjct: 483 LIPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTK 527
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 49.3 bits (117), Expect = 4e-09 Identities = 50/260 (19%), Positives = 97/260 (37%), Gaps = 22/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 + GK +TG A I +A+ + +GA + A Y +KL+ V A+ Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 CDVAEDTSIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDI 119 DV + +ID + A + + D V+ G L + A F + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVN--- 116 Query: 120 SSYSFVAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 S+ F A + M++ +++T+ A + +KA+ + + + Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 PEGVRVNAISAGPIRTLAASGI--------KDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 +R N +S G T + + + L + P+++ D+ ++ Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 231 FLCSDLSAGISGEVVHVDGG 250 FL S + I+ + VDGG Sbjct: 237 FLVSGQAGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 4e-12 Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 34 MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLSVGQIYRYFANKDAIIE 93 M K + ++ + I++ A R F + G + S+ +IA A ++ G IY +F +K + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 94 EMVRR 98 E+ Sbjct: 61 EIWEL 65
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.9 bits (114), Expect = 4e-08 Identities = 19/70 (27%), Positives = 39/70 (55%), Gaps = 1/70 (1%) Query: 52 PVSVVSELTGR-TSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNE 110 V +V+ G+ T + S E++P I+++ + KEG+ V+ G L ++ A +A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 111 ARAALQQAQA 120 +++L QA+ Sbjct: 139 TQSSLLQARL 148 Score = 30.6 bits (69), Expect = 0.010 Identities = 15/116 (12%), Positives = 32/116 (27%), Gaps = 9/116 (7%) Query: 94 QPLYQIDAASYQAAWN--EARAALQQAQALVKADCQKAQRYTRLVKENGVSQQDADDAQS 151 L A + A + K+ ++ + KE Q ++ Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE--YQLVTQLFKN 298 Query: 152 TCAQDKASVEAKKAALET----ARINLDWTTVTAPISGRI-GISSVTPGALVTASQ 202 L + + AP+S ++ + T G +VT ++ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1124 bits (2908), Expect = 0.0 Identities = 565/1005 (56%), Positives = 736/1005 (73%), Gaps = 6/1005 (0%) Query: 1 MPVAQYPDVAPPTIKISATYTGASAETLENSVTQVIEQQLTGLDNLLYFSSTSSSDGSVS 60 +PVAQYP +APP + +SA Y GA A+T++++VTQVIEQ + G+DNL+Y SSTS S GSV+ Sbjct: 30 LPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVT 89 Query: 61 INVTFEQGTDPDTAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKA 120 I +TF+ GTDPD AQVQVQNK+Q A LP EVQQ G++VEKS S++L++A Sbjct: 90 ITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGT 149 Query: 121 SSSDIADWLVSNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEA 180 + DI+D++ SNV+D L+R+ GVG +Q+FGA+YAMRIWLD L Y L P DV + ++ Sbjct: 150 TQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKV 209 Query: 181 QNVQVTAGKIGALPSPNTQQLTATVRAQSRLQTVDQFKNIIVKSQSDGAVVRIKDVARVE 240 QN Q+ AG++G P+ QQL A++ AQ+R + ++F + ++ SDG+VVR+KDVARVE Sbjct: 210 QNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVE 269 Query: 241 MGSEDYTAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQGYDIAYPKDS 300 +G E+Y I ++NG P+AG+ + L+ GANAL+TA +K K+AE Q PQG + YP D+ Sbjct: 270 LGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDT 329 Query: 301 TEFIKISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYS 360 T F+++S+ +V++TLFEAI+LV VMYLFLQN+RATLIP +AVPVVLLGTF +LA FGYS Sbjct: 330 TPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYS 389 Query: 361 INTLTLFAMVLAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVL 420 INTLT+F MVLAIGLLVDDAIVVVENVER+M ++ LP +EATEKSM +I GALV IA+VL Sbjct: 390 INTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVL 449 Query: 421 SAVFLPMAFFGGSTGVIYRQFSITIISAMLLSVVVALTLTPALCGSVL----QHVPPHKK 476 SAVF+PMAFFGGSTG IYRQFSITI+SAM LSV+VAL LTPALC ++L +K Sbjct: 450 SAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKG 509 Query: 477 GFFGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFLPTEDQG 536 GFFG FN + + + Y V +L R + +Y ++ GM ++ +LP SFLP EDQG Sbjct: 510 GFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQG 569 Query: 537 EIMVQYTLPAGATAARTAEVNRQIVDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAFVS 596 + LPAGAT RT +V Q+ D++L NEKAN + +FTV+GFSFSG QN GMAFVS Sbjct: 570 VFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629 Query: 597 LKNWSQRKGAENTAQAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLANGGT 656 LK W +R G EN+A+A+ RA ELG IRD V PA+ LG + GF FEL+ G Sbjct: 630 LKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGL 689 Query: 657 DRETLLQMRNQLIEKANQSP-ELHSVRANDLPQMPQLQVDIDSNKAVSLGLSLNDVTDTL 715 + L Q RNQL+ A Q P L SVR N L Q ++++D KA +LG+SL+D+ T+ Sbjct: 690 GHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTI 749 Query: 716 SSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSAFATTRWL 775 S+A GGTYVNDFIDRGRVKK+Y+Q D++FR P D+ K +VR ++ M PFSAF T+ W+ Sbjct: 750 STALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWV 809 Query: 776 YGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSGLSLQEKLAS 835 YG RL RYNG + EIQGE A G SSGDAM ME LA+ LPAG + W+G+S QE+L+ Sbjct: 810 YGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSG 869 Query: 836 GQALSLYAVSILVVFLCLAALYESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVA 895 QA +L A+S +VVFLCLAALYESWS+P SV+LV+PLG++G LAA + + NDVYF V Sbjct: 870 NQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVG 929 Query: 896 LLTTIGLSSKNAILIVEFA-EAAVAEGYSLSRAALRAAQTRLRPIIMTSLAFIAGVMPLA 954 LLTTIGLS+KNAILIVEFA + EG + A L A + RLRPI+MTSLAFI GV+PLA Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 955 IATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAG 999 I+ GAG+ ++ A+G G++GG ++ATLLAIFFVP+FFV+++R F G Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFKG 1034 Score = 75.6 bits (186), Expect = 6e-16 Identities = 53/330 (16%), Positives = 117/330 (35%), Gaps = 19/330 (5%) Query: 691 QLQVDIDSNKAVSLGLSLNDVTDTLSSA----WGGTYVNDFIDRGRVKKVYIQGDSEFRS 746 +++ +D++ L+ DV + L G G+ I + F++ Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 747 APSDLGKWFVRGSDN-AMTPFSAFATTRWLYGPER--LVRYNGSAA-----YEIQGENAT 798 P + GK +R + + ++ A L G + R NG A G NA Sbjct: 243 -PEEFGKVTLRVNSDGSVVRLKDVARVE-LGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 799 GFSSGDAMTKMEELANSLPAG--TTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAAL 856 + K+ EL P G + + + +L+ +LV + + Sbjct: 301 DTAKA-IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV-MYLF 358 Query: 857 YESWSVPFSVILVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFAEA 916 ++ + +P+ LLG + + ++ IGL +AI++VE E Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 917 AVAEGYSLSRAALRAAQTRLR-PIIMTSLAFIAGVMPLAIATGAGANSRIAIGTGIIGGT 975 + E + A + ++++ ++ ++ A +P+A G+ I+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 976 LTATLLAIFFVPLFFVLVKRLFAGKPRRQE 1005 + L+A+ P + + + + + Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENK 508
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.048 Identities = 24/166 (14%), Positives = 49/166 (29%), Gaps = 11/166 (6%) Query: 70 DVQKAIADIDSARALYGQTNASLFPTVNAALSSTRSRSLANGTGTTAEADGTVSSYTLDL 129 A AD ++ Q +RS L + + + + Sbjct: 128 TALGAEADTLKTQSSLLQARL----EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 130 FGRNQSLSRAARETWLASEFTAQNTRLTLIAEISTAWLTLAADNSNLALAKETMASAENS 189 R SL + TW ++ + AE T + + + ++ Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTV-------LARINRYENLSRVEKSR 236 Query: 190 LKIIQRQQQVGTAAATDVSEAMSVYQQARASVASYQTQVMQDKNAL 235 L A V E + Y +A + Y++Q+ Q ++ + Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 68.3 bits (167), Expect = 9e-15 Identities = 68/312 (21%), Positives = 114/312 (36%), Gaps = 18/312 (5%) Query: 5 SLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTITQLTLTASLIGLGVGQLLFGP 64 L L L +G L +P LP + L + +T L + Q P Sbjct: 6 PLIVILSTVALDAVG---IGLIMPVLPGLLRDLVHSNDVTA-HYGILLALYALMQFACAP 61 Query: 65 ----LSDKIGRKRPLILSLLLFIVSSILCATTNNIYWLVVWRFIQGIAGAGGSVLSRSIA 120 LSD+ GR+ L++SL V + AT ++ L + R + GI GA G+V IA Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA 121 Query: 121 RDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDWRTLFWVMAEISTVLLLGCLL 180 D G + F + G V PVLGG + F F+ A ++ + L Sbjct: 122 -DITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNFLTGCF 179 Query: 181 FINETLPENKRGSSL----LLTGRSVVQNRRFMRFCLIQSFMLAGLFAYIGSSSFVL--Q 234 + E+ +R L + + + F + L + ++ +V+ + Sbjct: 180 LLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF-IMQLVGQVPAALWVIFGE 238 Query: 235 KEFGFSPMQFSLVFGLNGI-GLIIASWIFSRLARRINAMTLLRGGLIAAILCALLTVLCA 293 F + + GI + + I +A R+ L G+IA +L Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 294 WIQLPIPALVAL 305 + P +V L Sbjct: 299 RGWMAFPIMVLL 310
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.007 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGKSLIAKAI 53 + GESG+GK L+A+A+ Sbjct: 165 ITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 9e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGLDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 9e-14 Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF06580#Sensor histidine kinase Length = 349 Score = 42.9 bits (101), Expect = 3e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 379 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 436 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 437 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 496 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 497 KRNIQEMGG---HVEIQSKQGTGTTIRILLP 524 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.009 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>FLAGELLIN#Flagellin signature. Length = 507 Score = 181 bits (460), Expect = 2e-52 Identities = 186/469 (39%), Positives = 243/469 (51%), Gaps = 11/469 (2%) Query: 2 AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 61 AQVINTNSLSL+TQNN+NK+QS+LSS+IERLSSGLRINSAKDDAAGQAIANRFTSNIKGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQASTGTNSDSDLDSIQDEIKSRLD 121 TQA+RNANDGIS+AQTTEGAL+EINNNLQR+REL+VQA+ GTNSDSDL SIQDEI+ RL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGQTITIDLKKIDSDTLGLNGFNVNGSGTI 181 EIDRVS QTQFNGV VL++D MKIQVGANDG+TITIDL+KID +LGL+GFNVNG Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 182 ANKAATISDLTAAKMDAATNTITTTNNALTASKALDQLKDGDTVTIKADAAQTATVYTYN 241 S D + + V A N Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRVDVNSG----------AVVTDTTAPTVPDKVYVN 230 Query: 242 ASAGNFSFSNVSNNTSAKAGDVAASLLPPAGQTASGVYKAASGEVNFDVDANGKITIGGQ 301 A+ G + + NNT+ S + + G+ D G Sbjct: 231 AANGQLTTDDAENNTAVDLFKTTKSTA-GTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDT 289 Query: 302 EAYLTSDGNLTTNDAGGATAATLDGLFKKAGDGQSIGFNKTASVTMGGTTYNFKTGADAG 361 + +G ++T G T+ + A + + + +V F Sbjct: 290 KTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTK 349 Query: 362 AATANAGVSFTDTASKETVLNKVATAKQGTAVAANGDTSATITYKSGVQTYQAVFAAGDG 421 +A + A K V A+ A + T A T + Sbjct: 350 NESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINED 409 Query: 422 TASAKYADNTDVSNATATYTDADGEMTTIGSYTTKYSIDANNGKVTVDS 470 A+AK + +++ + + D +++G+ ++ N TV + Sbjct: 410 AAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTN 458 Score = 95.1 bits (236), Expect = 8e-23 Identities = 95/371 (25%), Positives = 139/371 (37%), Gaps = 7/371 (1%) Query: 224 TVTIKADAAQTATVYTYNASAGNFSFSNVSNNTSAKAGDVAASLLPPAGQTASGVYKAAS 283 + + A+ +T T+ + + + L + + +G A Sbjct: 144 KIQVGANDGETITIDLQKIDVKS---LGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAV 200 Query: 284 GEVNFDVDANGKITIGGQEAYLTSDGNLTTNDAGGATAATLDGLFKKAGDGQSIGFNKTA 343 G + VD N + A D G T + + TA Sbjct: 201 GANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTA 260 Query: 344 SVTMGGTTYNFKTGADAGAATANAGVSFTDTASKETVLNKVATAKQGTAVAANGDTSATI 403 D T T + + + T+ Sbjct: 261 EAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAA 320 Query: 404 TYKSGVQTYQAVFAAGDGTASAKYADNTDVSNATATYTDADGEMTTIGSYTTKYSIDANN 463 + + T+ D + +D E +K +++ Sbjct: 321 NVDA----ATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAE 376 Query: 464 GKVTVDSGTGTGKYAPKVGAEVYVSANGTLTTDATSEGTVTKDPLKALDEAISSIDKFRS 523 T + + + DA + T +PL ++D A+S +D RS Sbjct: 377 YTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRS 436 Query: 524 SLGAIQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKAN 583 SLGAIQNR DSA+TNL NT TNL+ A+SRI+DADYATEVSNMSKAQI+QQAG SVLA+AN Sbjct: 437 SLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSKAQILQQAGTSVLAQAN 496 Query: 584 QVPQQVLSLLQ 594 QVPQ VLSLL+ Sbjct: 497 QVPQNVLSLLR 507
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 32.7 bits (74), Expect = 0.003 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 214 NGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQT 273 N E +VAA+N + + A+ + +S AL T++L V+T LT T T ++ Sbjct: 236 NSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTS--LLTPTSLTGGEES 293 Query: 274 AIKDWVNAYNSL 285 +KD VNA L Sbjct: 294 MLKDQVNALKGL 305
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.4 bits (118), Expect = 1e-08 Identities = 32/129 (24%), Positives = 58/129 (44%), Gaps = 20/129 (15%) Query: 153 AMMLH-IRQQAQAQLPEAITQAVIGRPINFQGLGGDEANTQAQGILERAAKRAGFKDVVF 211 M+ H I+Q + ++ P+ + + + I E +A+ AG ++V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV-------ERRAIRE-SAQGAGAREVFL 140 Query: 212 QYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREASLLGHSGCRI 271 EP+AA + + E +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 272 GGNDLDIAL 280 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 36.7 bits (85), Expect = 1e-04 Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 23/137 (16%) Query: 353 RLSYRLV---RSAEESKIALSSV--AETRASLPFISDELAT------LISQQGLESALSQ 401 R +Y + +AE K + S + + LA ++ + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 402 PLARILEQVQLALDNAQEKPDV--------IYLTGGSARSPLIKKALAEQLPGIPVAGGD 453 PL I+ V +AL+ Q P++ + LTGG A + + L E+ GIPV + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 454 D-FGSVTAGLARWAEVV 469 D V G + E++ Sbjct: 320 DPLTCVARGGGKALEMI 336
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.6 bits (103), Expect = 5e-07 Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 18/195 (9%) Query: 4 MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAMI-VDLNTNKVIYSNHP 62 M R+ + SL + +P A A + S+ +++ MI +DL + + + + Sbjct: 1 MRYIRLCIISL--LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 63 DLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRV---RLNSEISRKDM 119 D P+ S K++ VL DE+L+ I + YS V L ++ ++ Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 120 LLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFV--EPTGLS-----V 172 A+ S+N +AA+L GG + A + +G N TR E Sbjct: 119 CAAAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETELNEALPGDA 173 Query: 173 HNVSTARDLTKLLIA 187 + +T + L Sbjct: 174 RDTTTPASMAATLRK 188
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.6 bits (64), Expect = 0.015 Identities = 5/34 (14%), Positives = 16/34 (47%), Gaps = 2/34 (5%) Query: 164 WLHNLDQHLKHW-VWLILVVVL-VVGVRWWLKRS 195 L + ++ + W++L ++ + R L++ Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQE 248
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 63.9 bits (155), Expect = 2e-15 Identities = 39/128 (30%), Positives = 59/128 (46%), Gaps = 10/128 (7%) Query: 3 KQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNAVAPGAIA 62 + G I+ + S P +AY ++K A TK + LEL + I N V+PG+ Sbjct: 132 MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTE 191 Query: 63 TPMN-----GMDGGD--VKPDAEP---SIPLRRFGTTHEIASLVVWLCSEGANYTTGQSL 112 T M +G + +K E IPL++ +IA V++L S A + T +L Sbjct: 192 TDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNL 251 Query: 113 IVDGGFML 120 VDGG L Sbjct: 252 CVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 35.8 bits (82), Expect = 9e-06 Identities = 25/98 (25%), Positives = 44/98 (44%), Gaps = 1/98 (1%) Query: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLG 62 ++A IT + GIG+ A LA QG I ++ E+ K + AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKA-EARHAEAFPADVR 67 Query: 63 NLPEGAQALEKLIQRLGRIDVLVNNAGAMTKAPFLDMA 100 + + ++ + +G ID+LVN AG + ++ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLS 105
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.7 bits (67), Expect = 0.018 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 5/127 (3%) Query: 144 GAKAMREAVPAHLPVSVKVRLGWDSGEK-KFEIADAVQQAGATELVVHGRTKEQGY-RAE 201 G EA+ ++ + +G + E+ K EI A E+ V GR +G R Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 202 HIDWQAIGE-IRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVK 260 ++ I E +++ L V A + + IS V+ G GAL + NL R++ Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL-LRNLDRLL- 307 Query: 261 YNEPRMP 267 E +P Sbjct: 308 MEETGIP 314
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.4 bits (68), Expect = 0.027 Identities = 19/70 (27%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 503 LHVSTPASEYSQGQ-DLF---NPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNL 558 L V+ E + + LF QR H V+ +T+ + K L N NG+Y YN Sbjct: 926 LQVADKTGEPNHNELTLFDASKAQRDHLNVSLV-GNTVDLGAWKYKLR-NVNGRYDLYNP 983 Query: 559 RGERVKDEKP 568 E+ Sbjct: 984 EVEKRNQTVD 993
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 26.2 bits (57), Expect = 0.005 Identities = 10/35 (28%), Positives = 14/35 (40%) Query: 2 WSSAINSRNNVTTDAGAGFEQTLTGLTLGIDSRFS 36 W R + AG F+Q + G LG D + Sbjct: 650 WGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVA 684
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 539 bits (1390), Expect = 0.0 Identities = 258/386 (66%), Positives = 295/386 (76%), Gaps = 14/386 (3%) Query: 1 MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDDKSVDGDQTYMRLG 60 MK KVL+L++PALL AGAA+AAE+YNKDGNKLDLYGKVDGLHYFSDD S DGDQTYMR+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQVTDQLTGYGQWEYQIQGNAPESE-NNSWTRVAFAGLKFQDIGSFDYGRNYGVVY 119 FKGETQ+ DQLTGYGQWEY +Q N E E NSWTR+AFAGLKF D GSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVTSWTDVLPEFGGDTYG-SDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGQNGSVS 178 DV WTD+LPEFGGD+Y +DN+M R NG ATYRNTDFFGLVDGLNFA+QYQG+N S S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 GENDPDFTGHGITNNGRKALRQNGDGVGGSITYDY-EGFGVGAAVSSSKRTWDQNNT-GL 236 ++ G NNG NGDG G S TYD GF GAA ++S RT +Q N G Sbjct: 181 ADDVN--IGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGT 238 Query: 237 IGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL------GWANKAQNFEAVAQY 290 I GD+A+ +T GLKYDANNIYLA Y++T N T G G ANK QNFE AQY Sbjct: 239 IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQY 298 Query: 291 QFDFGLRPSVAYLQSKGKNLGVVAGRNYDDEDILKYVDVGATYYFNKNMSTYVDYKINLL 350 QFDFGLRP+V++L SKGK+L N DD+D++KY DVGATYYFNKN STYVDYKINLL Sbjct: 299 QFDFGLRPAVSFLMSKGKDLT-YNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLL 357 Query: 351 D-DNQFTRAAGINTDDIVALGLVYQF 375 D D+ F + AGI+TDDIVALG+VYQF Sbjct: 358 DDDDPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.7 bits (116), Expect = 7e-09 Identities = 26/145 (17%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 16 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP 75 M +++ADD + + ++L + + + ++ L + D +++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 76 GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGA------PT 129 + L+ IK+ P L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 130 DLPKALAALQKGKKFTPESVSRLLE 154 DL + + + + S+L + Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.0 bits (200), Expect = 6e-18 Identities = 29/106 (27%), Positives = 47/106 (44%) Query: 827 ILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLNKNHIDIVLSDVNMPNMDGYRL 886 ILV DD R +L L GY + ++ + D+V++DV MP+ + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 887 TQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVI 932 RI++ LPV+ ++A + E G L KP L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 562 bits (1449), Expect = 0.0 Identities = 181/484 (37%), Positives = 269/484 (55%), Gaps = 35/484 (7%) Query: 1 MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLFADIHPDVVLMDIRMPE 60 MT IL+ DD+ +R +L+ A + G++ +N T A D+V+ D+ MP+ Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 MDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRAL 120 + L ++ PV++M+A TA++A GA+DY+ KPFDL EL I+ RAL Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 QLQSMKKEIRHLHQALSTSWQWGH-ILTNSPAMMDICKDTAKIALSQASVLISGESGTGK 179 + L Q G ++ S AM +I + A++ + +++I+GESGTGK Sbjct: 120 AEP------KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK 173 Query: 180 ELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHEKGAFTGAQTLRQGLFERANEG 239 EL+ARA+H +R GPF+ +N AA+P L+ESELFGHEKGAFTGAQT G FE+A G Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 240 TLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFR 299 TL LDEIG+MP+ Q +LLR+LQ+ E+ +GG I+ D+RI+AATN+DL+ + +G FR Sbjct: 234 TLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFR 293 Query: 300 EDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWP 359 EDL+YRLNV+ L LPPLRDR EDI L HF+Q+ E + D A+ L+ A WP Sbjct: 294 EDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWP 352 Query: 360 GNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQPV---------CNAGEAKTAPVGERN- 409 GN+REL N++ R + +I E + ++R + +G + E N Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENM 412 Query: 410 ----------------LKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQE 453 + +E +I+ L GN+ + A +LG++R L K++E Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472 Query: 454 YGID 457 G+ Sbjct: 473 LGVS 476
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.1 bits (104), Expect = 7e-07 Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 2/165 (1%) Query: 34 LDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLIT 93 L IA +F+ +S ++ TA L ++ G L D +RL++ ++ G +I Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 ASSQSLA-MMILGTALTGLFSVVAQILVPLA-ATLASPDKRGKVVGTIMSGLLLGILLAR 151 S ++I+ + G + LV + A + RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLANLGGWRTVFWVASMLMALMALALWRGLPQMKSETHLNY 196 + G++A+ W + + + + + + +++ + H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.018 Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 23 PYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALG 82 P QE+ L + + L R A+G + + T + ++L ALG Sbjct: 756 PEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTI-------ADLVQALG 808 Query: 83 -----SSRTNATRIADELEKRGWIERRESDNDRR 111 SS ++ D L + GW RE+ RR Sbjct: 809 ADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRR 842
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 79.1 bits (195), Expect = 3e-18 Identities = 64/412 (15%), Positives = 120/412 (29%), Gaps = 97/412 (23%) Query: 29 LLLTLLFIIIAVAIGIYWFLVLRHFEETDDA----YVAGNQIQIMSQVSGSVTKVWADNT 84 L FI+ + I VL E A +G +I + V ++ Sbjct: 57 PRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 85 DFVKEGDVLVTLDPTDARQAFEKA------------------------------------ 108 + V++GDVL+ L A K Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 109 ----------------KTALASSVRQTHQLMINSKQLQANIEVQKIALAKA-------QS 145 K ++ Q +Q +N + +A + + +S Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 146 DYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQ 205 + L + I + + + A +L V Q ++ IL K E Q Q Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 206 AATEVRN------------------AWLALERTRIVSPMTGYVSRRAVQ-PGAQISPTTP 246 E+ + + + I +P++ V + V G ++ Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 247 LMAVVPA-TNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKY---TGKVVGLDMGTGS 302 LM +VP + V A + I + +GQ I + + +Y GKV + + Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNI-----N 409 Query: 303 AFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLRIGLSTLVSVNTTNR 354 ++ G V+ + + PL G++ + T R Sbjct: 410 LDAIE--DQRLGLVFNVIISIEENCLST--GNKNIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 132 bits (334), Expect = 8e-36 Identities = 97/405 (23%), Positives = 169/405 (41%), Gaps = 23/405 (5%) Query: 20 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 79 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 80 GEVKLFLWSTIAFAIASWACGVS-SSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAK 138 G +L L+ I S V S ++LI R IQG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 139 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETR 198 R A L V + GP +GG I+ HW + + +P+ + + L L +E R Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVR 194 Query: 199 TERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTD 258 + D G+ L+ +GI + ML F++ I +V+V++ + Sbjct: 195 I-KGHFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 259 DNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGI 318 +P VD L K+ F IG LC + + G + ++P ++++V+ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 319 IPVILS-PIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGF- 376 + VI+ I G + ++ +V F ++ S + I F Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFMTIIIVFV 358 Query: 377 --AVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSI 419 ++ ++TI S L + A SL NFT L+ G +I Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 293 bits (751), Expect = e-105 Identities = 132/170 (77%), Positives = 148/170 (87%) Query: 2 PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFA 61 PLLDSFTVDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ E+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIP 121 GFMRNHLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VADAW AAMEDVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLQEAQDIARNILERDVRINSNEELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA+NILE V +N N+ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 29.1 bits (65), Expect = 0.002 Identities = 27/114 (23%), Positives = 43/114 (37%), Gaps = 29/114 (25%) Query: 8 QQGFSLPEVMLAMVLMVMIVTA----------------LSGFQRTLMNSLASRNQYQQLW 51 Q+GF+L E+ML ++LM + L+ F+ L Q Q + Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFF 62 Query: 52 -----RHGWQ--QTQLRAISPPA----NWQVNRMQTSQAGCVSISVTLVSPGGR 94 WQ + R + PA W R +AG V+ S ++ GG+ Sbjct: 63 GVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSI--AGGK 114
>PilS_PF08805#PilS N terminal Length = 185 Score = 27.2 bits (60), Expect = 0.030 Identities = 12/50 (24%), Positives = 25/50 (50%) Query: 1 MSARRNRRMPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRESLTNT 50 S+ RR +++G +L+EVL+ + + VL A + +Q ++ Sbjct: 13 FSSLSARRKKEQDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSN 62
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.003 Identities = 9/24 (37%), Positives = 18/24 (75%) Query: 1 MKTQRGYTLIETLVAMLILVMLSA 24 QRG+TL+E +V ++I+ +L++ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLAS 27
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 611 bits (1577), Expect = 0.0 Identities = 189/571 (33%), Positives = 314/571 (54%), Gaps = 7/571 (1%) Query: 168 QTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEEAANEFRRYS 227 +I + A+ GVAIA+ + + + + S D + E E+LT ALE++ E R Sbjct: 2 HHKITGIAASSGVAIAKAFIHLEPNV--DIEKTSITDVSTEIEKLTAALEKSKEELRAIK 59 Query: 228 KRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSV-AEWAVKTVIEKFAEQFAAL 286 + A + A IF + +L D L + +++ + AE+A+K V + F F ++ Sbjct: 60 DQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESM 119 Query: 287 SDNYLKERAGDLRALGQRLLFHLDDANQGPNAW-PERFILVADELSATTLAELPQDRLVG 345 + Y+KERA D+R + +R+L HL G A E +++A++L+ + A+L + + G Sbjct: 120 DNEYMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKG 179 Query: 346 VVVRDGAANSHAAIMVRALGIPTVMGA-DIQPSVLHRRTLIVDGYRGELLVDPEPVLLQE 404 G SH+AIM R+L IP V+G ++ + H +IVDG G ++V+P ++ Sbjct: 180 FATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKA 239 Query: 405 YQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEKLGSRIDGIGLYRTE 464 Y+ + + + V P+ K G +++ N G + + L + +GIGLYRTE Sbjct: 240 YEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTE 299 Query: 465 IPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQLPYMPISEE-NPCLGWR 523 +M + P+EEEQ Y+ ++Q + KPV +RTLD+G DK+L Y+ + +E NP LG+R Sbjct: 300 FLYMDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFR 359 Query: 524 GIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVDEARRLIERAGREVEEMI 583 IR+ L++ +IF Q+RA+LRA + GNL ++ PM+ +L+E+ +A+ +++ ++ Sbjct: 360 AIRLCLEKQDIFRTQLRALLRA-STYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEG 418 Query: 584 GYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQYILAVDRNNTRVANIYDSL 643 +GIM+E+PS AK VDF S+GTNDL QY +A DR N RV+ +Y Sbjct: 419 VDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPY 478 Query: 644 HPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILIGLGYRHLSMNGRSVARVKYLL 703 HPA+LR + M+ + A G + +CGEMAGD + + +L+GLG SM+ S+ + L Sbjct: 479 HPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQL 538 Query: 704 RRIDFAEAENLAQRSLEAQLATEVRHQVAAF 734 ++ E + AQ++L A EV V Sbjct: 539 LKLSKEELKPFAQKALMLDTAEEVEQLVKKT 569
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 73.1 bits (179), Expect = 3e-16 Identities = 30/184 (16%), Positives = 63/184 (34%), Gaps = 38/184 (20%) Query: 104 GLGSGVIINANKGYVLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQ 151 + SGV++ + +LTN HV++ L +G ++ + Sbjct: 102 FIASGVVVGKDT--LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 152 SDIALLQIQN-------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIISALG 204 D+A+++ + ++++ + +V G P ++ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 205 RSGLNLEGLEN-FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 263 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 264 MART 267 + Sbjct: 264 VFIN 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 53.1 bits (127), Expect = 6e-10 Identities = 33/160 (20%), Positives = 61/160 (38%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKINATGGLPTIP--INPRRVPH-----IGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + I + P + + + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.5 bits (63), Expect = 0.036 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 25 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 84 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 85 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 126 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 127 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 168 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 168 bits (428), Expect = 9e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKELYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 2e-10 Identities = 29/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQVLFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG VL + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.4 bits (63), Expect = 0.043 Identities = 12/72 (16%), Positives = 20/72 (27%), Gaps = 3/72 (4%) Query: 296 MMPQVLPSPDAMGPKLPEPATGITQPTPQQPATGNAVTAPAAPTQPAANRSPQRATPPQS 355 P+ +P P P + E +P P+ V P +P +R Sbjct: 78 PEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK---KVEQPKRDVKPVESRPASPFENTAP 134 Query: 356 GAQPPARAPGGQ 367 + A Sbjct: 135 ARPTSSTATAAT 146
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 580 bits (1498), Expect = 0.0 Identities = 347/347 (100%), Positives = 347/347 (100%) Query: 26 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 85 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAK 60 Query: 86 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 145 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ Sbjct: 61 QMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQ 120 Query: 146 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 205 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG Sbjct: 121 VERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNG 180 Query: 206 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 265 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN Sbjct: 181 VVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRN 240 Query: 266 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 325 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL Sbjct: 241 LAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALL 300 Query: 326 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 372 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE Sbjct: 301 RNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.026 Identities = 11/28 (39%), Positives = 17/28 (60%) Query: 150 VVVTGASGGVGSTAVALLHKLGYQVVAV 177 +VTGA+G +G L + G+QVV + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 128 bits (323), Expect = 3e-39 Identities = 76/209 (36%), Positives = 122/209 (58%), Gaps = 3/209 (1%) Query: 1 MAKRTKAKALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFN 60 MA++TK +A +TRQ +++ A+ F+Q GVS T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-LQQPSLRELIQDHLTAGLEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEF 119 E+W L + ++ EL + A DP LRE LI L+ R++ L++I++HKCEF Sbjct: 61 EIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 NDEM-LAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLDVVMIIIDGAFSGIVQNWL 178 EM + + R + + + L+ C + + +L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNMAGYDLYKQAPALVDNVLRMFMPDENI 207 +DL K+A V +L M++ + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTL 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 38/217 (17%), Positives = 70/217 (32%), Gaps = 38/217 (17%) Query: 98 ATYQASYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 215 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 270 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 271 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEG 299 G + + ++ N L GM V A I G Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 7e-04 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 46 TAPLEVKTELPGR-TNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQASY 104 +E+ G+ T++ R E++P + IV EG V+ G L ++ +A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVE 164 + K++++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191 Score = 29.0 bits (65), Expect = 0.031 Identities = 11/34 (32%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 65 AEVRPQVSGIVLNRN-FTEGSDVQAGQSLYQIDP 97 + +R VS V TEG V ++L I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1404 bits (3636), Expect = 0.0 Identities = 1028/1034 (99%), Positives = 1032/1034 (99%) Query: 1 MANFFIRRPIFAWVLAIILMIAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILM+AGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIQEVVKTLFEAIMLVFLVMYLFLQ 360 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSI EVVKTLFEAIMLVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDKLPPREATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MEDKLPP+EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERSGDENSAEAVIHRAKMELGKIRDG 660 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEER+GDENSAEAVIHRAKMELGKIRDG Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRM 780 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK+YVQADAKFRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVIRRCFKG 1034 VPVFFVVIRRCFKG Sbjct: 1021 VPVFFVVIRRCFKG 1034
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 83.9 bits (207), Expect = 4e-21 Identities = 53/200 (26%), Positives = 94/200 (47%), Gaps = 15/200 (7%) Query: 59 EFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSNDETSFVLINEGNEQKRY 118 +F+L + +N AG DA N L+++L G++ +D S +I++ NEQ Sbjct: 64 DFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSR 122 Query: 119 SLNEALESAPGT--FIRKINKTSVVFETHGHYEKVTLH-------PGLP--DIIKQPDSE 167 +NE + PG I I VV + G YE + L+ G+P + +Q Sbjct: 123 GVNEEV---PGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGAQVNEQLQQR 179 Query: 168 NQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNLSLTHPDEVS 227 ++DY+ +PI + ++ G RLNP ++F LQ D+A+ +N L L ++ Sbjct: 180 ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAK 239 Query: 228 QALSLLLTQQSAQFTIRRNG 247 +A+ + + T+ R+G Sbjct: 240 KAMERMADVHNFTLTVERDG 259
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 716 bits (1850), Expect = 0.0 Identities = 344/629 (54%), Positives = 466/629 (74%), Gaps = 11/629 (1%) Query: 11 ITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRS 70 +T + AALL A E++ A+F DI++F+ V ++L KT++IDPSV+GTI+VRS Sbjct: 12 LTLLIFAALLF---RPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 71 NDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTSPGMIADSSRPGVGDELV 130 D ++++YYQFFLS+LD+YG++VI ++NG LKVVRS + KT+ +A + PG+GDE+V Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVV 128 Query: 131 TRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDV 190 TR+VPL NV ARDLAPLLRQ+ D VG+VVHYEPSNVL++TGRA+ I +L+ +++RVD Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 191 IGTEKQQIIHLEYASAEDLAEILNQLISESHGKSQMPALLSAKIVADKRTNSLIISGPEK 250 G + L +ASA D+ +++ +L ++ KS +P + A +VAD+RTN++++SG Sbjct: 189 AGDRSVVTVPLSWASAADVVKLVTEL-NKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 251 ARQRITSLLKSLDVEESEEGNTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNSRKPSSTS 310 +RQRI +++K LD +++ +GNT+V YLKYAKA++LVEVLTG+S ++ EK ++ + Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAK--PVAA 305 Query: 311 AMDNVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNLG 370 N+ I A QTN+L++TA V L VIA+LDIRR QVLVEAII EVQD +GLNLG Sbjct: 306 LDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLG 365 Query: 371 VQWANKNVGAQQFTNTGLPVFNAAQGVADYKKNGGITSANPAWDMFSAYNGMAAGFFNGD 430 +QWANKN G QFTN+GLP+ A G Y K+G ++S+ S++NG+AAGF+ G+ Sbjct: 366 IQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLA--SALSSFNGIAAGFYQGN 423 Query: 431 WGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERKT 490 W +LLTAL+S+ KNDILATPSIVTLDN A+FNVGQ+VPVL+GSQTTSGDN+FNTVERKT Sbjct: 424 WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKT 483 Query: 491 VGTKLKVTPQVNEGDAVLLEIEQEVSSVD---SSSNSTLGPTFNTRTIQNAVLVKTGETV 547 VG KLKV PQ+NEGD+VLLEIEQEVSSV SS++S LG TFNTRT+ NAVLV +GETV Sbjct: 484 VGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETV 543 Query: 548 VLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSL 607 V+GGLLD + KVPLLGDIP++G LFR TS + +KRNLM+FIRPT+IRD D YR Sbjct: 544 VVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQA 603 Query: 608 SKEKYTRYRQEQQLRIDGKSKALIGSEDL 636 S +YT + Q + ++ + ++DL Sbjct: 604 SSGQYTAFNDAQSKQRGKENNDAMLNQDL 632
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 512 bits (1321), Expect = 0.0 Identities = 195/405 (48%), Positives = 283/405 (69%), Gaps = 8/405 (1%) Query: 2 NYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQK-------SSGVKTRRP 54 Y Y+A+ G+K +G +A+ RQAR LRE GL L + + S+G+ RR Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 55 -RISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNNRLADVLNQVRSAILEGHPLSD 113 R+S S+L L TRQLATL AA++PLEE+L + +QS L+ ++ VRS ++EGH L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 114 ALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKLIQSLIYPCMLTTV 173 A++ FP F+ LY +V AGE SG L VL +LADY E RQ++RS++ Q++IYPC+LT V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 174 AIVVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTGPTLLATVFIVAVGFW 233 AI VV ILL+ VVPK+ EQF+HMKQ LPLSTR+L+G+SD ++ GP +L + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 234 LWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQSSGVPLLDGMNLSTESLN 293 + L++ R FH LL + LIG + +N+ARY RTLSIL +S VPLL M +S + ++ Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 294 NLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVASGEKSGQLGTLMVRAADNQE 353 N R RL+ A + VR+G S+H +LEQTA+FPPMM +M+ASGE+SG+L +++ RAADNQ+ Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 354 TLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQLNSMIN 398 +++ L L +FEP L+++MA +VLFIV+++LQP+LQLN++++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 249 bits (636), Expect = 1e-88 Identities = 144/145 (99%), Positives = 144/145 (99%) Query: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNHRYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 LDNH YPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145 LSAGPDGEMGTEDDITNWGLSKKKK Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 12 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 69 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 70 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 119 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 120 RYDALNRYPMSDVLR 134 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.005 Identities = 27/152 (17%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQNRKAELTAC 602 +LE++ + +L A+ + EE+ SE Q+ + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.7 bits (74), Expect = 0.005 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQNRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 50.3 bits (120), Expect = 3e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 228 REREHGTVEHLLVMPITPFEIMMAKV-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 286 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 287 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 345 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 346 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 395 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.047 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 84.5 bits (209), Expect = 4e-20 Identities = 71/408 (17%), Positives = 139/408 (34%), Gaps = 81/408 (19%) Query: 6 RHLAWWVVGALAVAAVVAWWLLRPAGVP-EGFAVSNGRIEATEVDIASKIAGRIDTILVK 64 R +A++++G L +A +++ G +GR + I + I+VK Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVK 113 Query: 65 EGQFVREGEVLAKMDTRV----------------LQEQRLEAI----------------- 91 EG+ VR+G+VL K+ L++ R + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 -------------------AQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDSV 132 Q Q+ + L+++++E + +N+ + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 133 AKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ-- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 191 -----------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAAG 236 QT T + S ++AP +V Q +V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 237 GRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTP 295 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNINL 410 Query: 296 KTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 411 DAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.033 Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 226 ENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFL--NEQRNAHPNQSLKNTL 283 E + RG GP +L + ++ + + + L T + N Q A N LK L Sbjct: 63 EAITLRERGWKGP-ILMLEGFFHAQD---LEIYDQHRLTTCVHSNWQLKALQNARLKAPL 118 Query: 284 AVHL------------PKRLVERLQQLGQIPDVSLKQL 309 ++L P R++ QQL + +V L Sbjct: 119 DIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTL 156
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.2 bits (94), Expect = 1e-05 Identities = 36/208 (17%), Positives = 72/208 (34%), Gaps = 13/208 (6%) Query: 88 IIVEFLPVSLLTP----MAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDR--RY 141 + ++ + + L+ P + +DL S V + A A+ +DR R Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 142 VVILFAVLL-TLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 200 V+L ++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 201 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAAMG----VLCIFWIIKSLPSLPGE 256 + +V LG +G F AAAA+ + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 257 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 284 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 37.8 bits (88), Expect = 1e-04 Identities = 30/105 (28%), Positives = 43/105 (40%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG-AEYAD---------APA 71 V+R D +I N ILD + G + I +K IA +G A D P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/168 (16%), Positives = 61/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.2 bits (94), Expect = 1e-05 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 30 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 87 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 88 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 144 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 145 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAASALHYGWRAGMMIAGCMAIVVGIFLC 203 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 204 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 263 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 264 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 307 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 308 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 366 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 367 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 396 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>PF06580#Sensor histidine kinase Length = 349 Score = 39.5 bits (92), Expect = 2e-05 Identities = 28/142 (19%), Positives = 57/142 (40%), Gaps = 11/142 (7%) Query: 367 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNN 426 LR ++L + + ++L L++ + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 427 IVKHA-----DASAVTLQGWQHDERLMLVIEDDGSGLPPDSGQ-HGFGLTGMRERVTALG 480 +KH + L+G + + + L +E+ GS ++ + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 481 G---TLTISCLHG-TRVSVSLP 498 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.5 bits (144), Expect = 7e-12 Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 1/184 (0%) Query: 7 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYG 66 R+ +L+ L +L + + + ++ D+A D N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 67 PISDRVGRRPVILVGMSIFMLATLVA-VTTSSLTVLIAASAMQGMGTGVGGVMARTLPRD 125 +SD++G + ++L G+ I +++ V S ++LI A +QG G + + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 126 LYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWM 185 + A L+ + + + P IGG++ +W L ++ V F M Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLK 190 Query: 186 PETR 189 E R Sbjct: 191 KEVR 194
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 3e-04 Identities = 19/96 (19%), Positives = 37/96 (38%), Gaps = 16/96 (16%) Query: 356 NLYLNAIQAIGQHGVISVTASESGAGVKISVTDSGKGIAADQLEAIFTPYFTTKAEGTGL 415 N + I + Q G I + ++ V + V ++G + E TG Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT------------KESTGT 313 Query: 416 GLAVVHNIVEQHGG---TIQVASQEGKGATFTLWLP 448 GL V ++ G I+++ ++GK + +P Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 527 bits (1359), Expect = 0.0 Identities = 184/468 (39%), Positives = 253/468 (54%), Gaps = 35/468 (7%) Query: 8 ILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIAT 67 ILV DDD + T+L L GY+V + ++ + DLV+ DV M + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEIKTLNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHSV 127 L IK P +PVL+M+A ++ TA++A + GA DYL KP D L + +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 128 DAETPAVSASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSA 187 ++ S +VG+S AMQ + +A + ++ T++I G+SGTGKELVARA+H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 188 RSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISP 247 R P V +N AA+ L+ESELFGHEKGAFTGA R GRF +A+GGTLFLDEIGD+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 248 MMQVRLLRAIQEREVQRVGSNQTISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAI 307 Q RLLR +Q+ E VG I DVR++AAT++DL +N G FR+DLYYRLNVV + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 308 EVPSLRQRREDIPLLANHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVER 367 +P LR R EDIP L HF+Q+ + VK F +A++L+ + WPGN+RELEN V R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 368 AVVLLTGEYISERELPLAIASTPIPLVQSQDIQP-------------------------- 401 L + I+ + + S + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 402 --------LVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR 441 L E+E +ILAAL T GN+ +AA LG+ R TL K+ Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.7 bits (72), Expect = 6e-04 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 49 IANFFVAEKVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVA 108 IA+FFV EK+LQ + Q+H S P+ R+ + V G +QVE R + E Sbjct: 81 IADFFVTEKMLQHFIKQVHSNSF---MRPSPRVLVCVPV------GATQVERRAIRESAQ 131 Query: 109 GA 110 GA Sbjct: 132 GA 133
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 4e-04 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 5/52 (9%) Query: 78 IDPDVRGCGVGRMLVKHALSMAPE-----LTTNVNEQNEQAVGFYKKVGFKV 124 + D R GVG L+ A+ A E L + N A FY K F + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.016 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.0 bits (104), Expect = 9e-07 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 55/290 (18%) Query: 96 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGE 155 G L D++GR+ +L +++ ++ + P +W +L I ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 156 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLDWGW 211 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 212 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRS 271 PFF A L + L K E+ P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 272 LLTCIGLVIATNVTYYML----LTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVM 326 +T + ++A ++ + H+ G+ + ++ L + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 327 GLLSDRFGRRPFVLLG----SVALFVLA--------IPAFILINSNVIGL 364 G ++ R G R ++LG +LA P +L+ S IG+ Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Score = 39.4 bits (92), Expect = 2e-05 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 297 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFI 355 L H+ + +G+L+ + A+M PV+G LSDRFGRRP +L+ L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLVS---LAGAAVDYAI 89 Query: 356 LINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIR---YSALAAAFNISVLVAG 412 + + + +++ G ++A I V + + + R + ++A F +VAG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 413 LTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITG-VTMKETANR 455 P L + S + P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFSPH--APFFAAAALNGLNFLTGCFLLPESHKG 187
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 7e-05 Identities = 39/182 (21%), Positives = 80/182 (43%), Gaps = 34/182 (18%) Query: 184 ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDV-ILPSYDELSTML--DQRQQTLL 240 + +M+ S+S+L++ S N + V L +++ ++ SY +L+++ D+ Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 241 LPESAADITVQGDATLLRMLLRNLVENAHRY----SPQGSNIMIKLQEDGGAV-MAVEDE 295 + + D+ V ML++ LVEN ++ PQG I++K +D G V + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 296 GPGIDESKCGELSKAFVRMDSRYGGIGLGLSIV-SRITQLHHGQFFLQNRQETSGTRAWI 354 G + + G GL V R+ L+ + ++ ++ A + Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 355 RL 356 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 1e-23 Identities = 42/121 (34%), Positives = 60/121 (49%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDGVSTARMAEQSLEAGHYSLVVLDLGLPDEDGLH 61 IL+ +DD + L A GY S A + + AG LVV D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNN 121 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 Q 122 + Sbjct: 125 R 125
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.4 bits (68), Expect = 0.004 Identities = 30/158 (18%), Positives = 49/158 (31%), Gaps = 9/158 (5%) Query: 3 WRKRGYLLAAMLAFASATIQAADVTITVNGKVVAKPCTVSTTNATVDLGDLYSFSLMSAG 62 W R + A LA + +TI + VT VN + + + + G Sbjct: 258 WMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTH------IG 311 Query: 63 AASAWHDVALELTNCPVG--TSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLN 120 W L + P G + S + Q ++QN + N+ Sbjct: 312 TLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQ 371 Query: 121 TGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQA 158 + QV D + V +N A GTI+ Sbjct: 372 KTEIQPTQVIDGPFAGGKNTVVNINRINTNA-DGTIRV 408
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.1 bits (62), Expect = 0.045 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 214 SQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVS 273 S+N G ++ +A+ N FT PA V V L ++G ++ + + + Sbjct: 133 SENAGKEITIGSAN-PNVTFTEKTGDQPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYN 191 Query: 274 LGLTANYARTGGQVTAGNV 292 + TG VT G V Sbjct: 192 SNVNFYDVTTGATVTTGAV 210
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 10/49 (20%), Positives = 25/49 (51%) Query: 230 LVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFV 278 + +I ++ I +W V +T W ++ FI + P+A + + ++ + Sbjct: 73 MGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSII 121
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 153 bits (389), Expect = 1e-47 Identities = 46/110 (41%), Positives = 66/110 (60%) Query: 1 MIEVPAAVMIADKLASEVDFFSIGTNDLTQYIMAADRGNSTVAKLVDYCNDAVINAIAMV 60 M+E+P+ + A+ A EVDFFSIGTNDL QY MAADR N V+ L + A++ + MV Sbjct: 430 MVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMV 489 Query: 61 CQAGRNNEIPVSMCGEMAGDIQQTARLLTMGIDKLSASPSRLPALKAAIR 110 +A + V MCGEMAGD LL +G+D+ S S + + ++ + Sbjct: 490 IKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLL 539
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 28.8 bits (64), Expect = 0.017 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 9e-23 Identities = 34/139 (24%), Positives = 61/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFDVEVFERGLPVLDKARQQVPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+DV + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSTPSPVIRIGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.006 Identities = 41/182 (22%), Positives = 72/182 (39%), Gaps = 40/182 (21%) Query: 312 LRQARLENRQEVVLTAVDVAALFR---RVSEARTVQLAE--KNITLHVM--------PTE 358 +R LE+ + ++ L R R S AR V LA+ + ++ + Sbjct: 182 IRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ 241 Query: 359 VNVASEPALLEQALGNLL-----DNA----IDFTPESGCITLSAEVDQEYVTLKVLDTGS 409 PA+++ + +L +N I P+ G I L D VTL+V +TGS Sbjct: 242 FENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 410 GIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE-VARLFNGEVTLR-NVQEGGVLASL 467 N ++S+G GL V E + L+ E ++ + ++G V A + Sbjct: 302 LALK----------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 468 RL 469 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122