>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.9 bits (69), Expect = 0.036 Identities = 36/173 (20%), Positives = 71/173 (41%), Gaps = 19/173 (10%) Query: 121 QEESQLKERILKRKNEKIILNVNFIGEEVLGEEEANARFEKY---SQALKSNYIQYISIK 177 Q+ S+ ++ + + EK+ F+ E+ + + Y S+ K Y + Sbjct: 118 QDLSEEEKNSMNSRGEKVPFASRFVFEKKRETPKLIINIKDYAINSEQSKEVYYEIGKGI 177 Query: 178 ITTIFSQINILDFEY-----SKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLE 232 I S+ LD E+ S + D L++ +E K + K I+++ ++ Sbjct: 178 SLDIISKDKSLDPEFLNLIKSLSDDSDSSDLLFSQKFKE-KLELNNKSIDINF-----IK 231 Query: 233 LTVESFMESIAK-----FDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLK 280 + F + + F + VL+ Y PD +EY+ KL E++ + LK Sbjct: 232 ENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFEYMNKLEKGGFEKISESLK 284
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.8 bits (82), Expect = 1e-04 Identities = 37/206 (17%), Positives = 75/206 (36%), Gaps = 2/206 (0%) Query: 17 ELEARIGELEDENTELFTTKDKLTKENTELASQNTALTEKNKTLTTENDKLNHQVIALTN 76 + E L+ +N++L L N EL + + EK + + ++ L Sbjct: 61 KFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEA 120 Query: 77 EQNSLEQERAELQDEHGFLEKSCANLEKENQRLTDKLKQLESAQKNLENSNTQLRQALEN 136 + LE+ + LE E L + LE A + N +T ++ Sbjct: 121 RKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKT 180 Query: 137 SNAQLAQAEEKIAEEKTELEREIARLKSLEGMEAKSDLDLANRRLASANQDLKRQKRKLE 196 A+ A E + AE + LE + + L+ LA+ DL++ Sbjct: 181 LEAEKAALEARQAELEKALEGAMNFSTADS--AKIKTLEAEKAALAARKADLEKALEGAM 238 Query: 197 EENIALKERVDSLKEQLFTLQPQKPQ 222 + A ++ +L+ + L+ ++ + Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAE 264 Score = 35.0 bits (80), Expect = 2e-04 Identities = 43/207 (20%), Positives = 78/207 (37%), Gaps = 2/207 (0%) Query: 16 EELEARIGELEDENTELFTTKDKLTKENTELASQNTALTEKNKTLTTENDKLNHQVIALT 75 + L+ EL +E + K K +E AS+ L + L + + A + Sbjct: 81 KALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADS 140 Query: 76 NEQNSLEQERAELQDEHGFLEKSCANLEKENQRLTDKLKQLESAQKNLENSNTQLRQALE 135 + +LE E+A L LEK+ + + K+K LE+ + LE +L +ALE Sbjct: 141 AKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALE 200 Query: 136 NSNAQLAQAEEKIAEEKTELEREIARLKSLEGMEAKSDLDLANRRLASANQDLKRQKRKL 195 + KI + E AR LE +A + ++ + L+ +K L Sbjct: 201 GAMNFSTADSAKIKTLEAEKAALAARKADLE--KALEGAMNFSTADSAKIKTLEAEKAAL 258 Query: 196 EEENIALKERVDSLKEQLFTLQPQKPQ 222 E L++ ++ + Sbjct: 259 EARQAELEKALEGAMNFSTADSAKIKT 285 Score = 34.7 bits (79), Expect = 3e-04 Identities = 41/219 (18%), Positives = 72/219 (32%), Gaps = 9/219 (4%) Query: 4 LIEKWFGFSQIREELEARIGELEDENTELFTTKDKLTKENTELASQNTALTEKNKTLTTE 63 L + + E + L K L EL + + + Sbjct: 153 LAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK 212 Query: 64 NDKLNHQVIALTNEQNSLEQERAELQDEHGFLEKSCANLEKENQRLTDKLKQLESAQKNL 123 L + AL + LE+ + LE E L + +LE A + Sbjct: 213 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 272 Query: 124 ENSNTQLRQALENSNAQLAQAEEKIAEEKTELEREIARLKSLEGMEAKSDLDLANRRLAS 183 N +T ++ A+ A E + A+ + + + A +SL S Sbjct: 273 MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDAS---------RE 323 Query: 184 ANQDLKRQKRKLEEENIALKERVDSLKEQLFTLQPQKPQ 222 A + L+ + +KLEE+N + SL+ L + K Q Sbjct: 324 AKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ 362
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.6 bits (64), Expect = 0.023 Identities = 17/58 (29%), Positives = 24/58 (41%), Gaps = 9/58 (15%) Query: 39 RHVFDDEKTAKTFKVELRASEPCAYAISALKSYGFFKSEKLDKPVYYGVFDFGGGTTD 96 R + + + A +V L EP A AI A + + V D GGGTT+ Sbjct: 124 RAIRESAQGAGAREVFL-IEEPMAAAIGA--------GLPVSEATGSMVVDIGGGTTE 172
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1044 bits (2701), Expect = 0.0 Identities = 353/569 (62%), Positives = 442/569 (77%), Gaps = 4/569 (0%) Query: 3 KISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSN-NP 61 ++SR Y +M+GPT GDKVRL DT+L EVE D+T +GEE+KFGGGK +R+GM QS Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 62 SKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEAL 121 +D +ITNALI+D+ GI KADIG+KDG+IA IGK GN DMQ GV + VGP TE + Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGV--TIIVGPGTEVI 121 Query: 122 AGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKW 181 AGEG IVTAGG+D+HIHFI PQQI A SG+T M+GGGTGPA GT ATT TPG ++ Sbjct: 122 AGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIAR 181 Query: 182 MLRAAEEYSMNLGFLAKGNTSNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKY 241 M+ AA+ + MNL F KGN S +L + + GA K+HEDWGTTP+AI+ L VAD+Y Sbjct: 182 MIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEY 241 Query: 242 DVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTN 301 DVQV IHTDTLNE+G VEDT+AAI GRT+H +HTEGAGGGHAPDII++ G+ N++P+STN Sbjct: 242 DVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTN 301 Query: 302 PTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSS 361 PT P+TVNT AEH+DMLMVCHHL +I ED+ FA+SRIR +TIAAED LHD+G FSI SS Sbjct: 302 PTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISS 361 Query: 362 DSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISE 421 DSQAMGRVGEV RTWQTADK K++ GRLKEE GDNDNFR+KRY++KYTINPAIAHG+S Sbjct: 362 DSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSH 421 Query: 422 YVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAH 481 +GS+EVGK ADLVLW+PAFFGVKP+M++ GG IA + MGD NASIPTPQPV+YR MF Sbjct: 422 EIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGA 481 Query: 482 HGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCR-NITKKDMQFNDTTAHIEVNP 540 +G+++ ++++TFVSQA+ D G+ LG+ ++++ V+N R I K M N T HIEV+P Sbjct: 482 YGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDP 541 Query: 541 ETYHVFVDGKEVTSKPANKVSLAQLFSIF 569 ETY V DG+ +T +PA + +AQ + +F Sbjct: 542 ETYEVRADGELLTCEPATVLPMAQRYFLF 570
>FLAGELLIN#Flagellin signature. Length = 507 Score = 33.5 bits (76), Expect = 0.002 Identities = 32/285 (11%), Positives = 80/285 (28%), Gaps = 6/285 (2%) Query: 17 SVLLGSMNATDLETYAALQKPSHVFSNYAKKSNKGSELSSDSLTQQQAQNTAQSDTTQAT 76 ++ L ++ L + KS+ + D+ + ++ Sbjct: 156 TIDLQKIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVV 215 Query: 77 TLENTASSGTP----DSSTLPTKETPPATSGGTGGDKHTASSGTPPASSTPPAKKDETSG 132 T + ++ T + + +++GT A + A K G Sbjct: 216 TDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEG 275 Query: 133 SGDKDQHTASGTGGTPSSSGGTGGDKHTASSGTPPASSTPPTPTPPTSGGNTITSQLTKD 192 D + T T + + G G T + + T T+ S Sbjct: 276 D-TFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVY 334 Query: 193 TTTVNNLKSVSVSAMNTTLSGVTQLSQQTATISTLLNGSPNLGSVISNAQGLSSAFSALE 252 T+ VN + N + + + + + + + ++ A + Sbjct: 335 TSVVNGQFTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMF 394 Query: 253 SAQNTLKGYLDSSSATIGQLTNGSNAVVGALDKAINQVDMALADL 297 + + + + ++D A+++VD + L Sbjct: 395 IDKTASGVSTLINEDAAAAKK-STANPLASIDSALSKVDAVRSSL 438 Score = 31.2 bits (70), Expect = 0.013 Identities = 38/306 (12%), Positives = 85/306 (27%), Gaps = 10/306 (3%) Query: 55 SSDSLTQQQAQNTAQSDTTQATTLENTASSGTPDSSTLPTKETPPATSGGTGGDKHTASS 114 SL + T + + D+ + + + G TA + Sbjct: 163 DVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPT 222 Query: 115 GTPPASSTPPAKKDETSGSGDKDQHTASGTGGTPSSSGGTGGDKHTASSGTPPASSTPPT 174 A T+ + + ++ A G + Sbjct: 223 VPDKVYVNA-ANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYK 281 Query: 175 PTPPTSGGNTITSQLTKDTTTVNNLKSVSVSAMNTTLSGVTQLSQQTA---TISTLLNGS 231 T T K +TT+N K A T + + + ++++NG Sbjct: 282 GVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQ 341 Query: 232 PNLGSVISNAQGLSSAFSALESAQNTLKGYLDSSSATIGQLTNGSNAVVGALDKAINQVD 291 N S A + + K ++ + T + + Sbjct: 342 FTFDDKTKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASG 401 Query: 292 MALADLATADTQKTQAVALVAASNSATTTTDAINFLNALKANLTAQKDAFMSVHKNIQTA 351 ++ A A + +N + A++ ++A++++L A ++ F S N+ Sbjct: 402 VSTLINEDAAA------AKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNT 455 Query: 352 VAQAQA 357 V + Sbjct: 456 VTNLNS 461
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 225 bits (575), Expect = 6e-79 Identities = 57/145 (39%), Positives = 91/145 (62%), Gaps = 7/145 (4%) Query: 5 VESFNLDHTKVKAPYVRVADRKKGVNGDLIVKYDVRFKQPNQDHMDMPSLHSLEHLVAEI 64 ++SF +DHT++ AP VRVA + GD I +D+RF PN+D + +H+LEHL A Sbjct: 3 LDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYAGF 62 Query: 65 IRNHA----SYVVDWSPMGCQTGFYLTVLNHDNYTEILEVLEKTMQDVLKAK---EVPAS 117 +RNH ++D SPMGC+TGFY++++ + ++ + M+DVLK + ++P Sbjct: 63 MRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIPEL 122 Query: 118 NEKQCGWAANHTLEGAQNLARAFLD 142 NE QCG AA H+L+ A+ +A+ L+ Sbjct: 123 NEYQCGTAAMHSLDEAKQIAKNILE 147
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 28.5 bits (63), Expect = 0.029 Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 2/103 (1%) Query: 7 EDNKKLYDIIDGQQRTTTIFMLLHVLASKQNEKDKQETRKYLYQKGELKLEVAPQNQSFF 66 DN+ + + +G+ + +T F+L A + ++ + Y++ ++ E+A + F Sbjct: 93 LDNENVR-LFNGRDKDSTSFILGDEFAVLRFYRNGESISYIAYKEAQMMNEIAEFYAAPF 151 Query: 67 KTLLEAAEKENISHCEKDADTEGKQNLFEVLKAILDKVSKLSG 109 K EKE C D+ T +K +DK K+ Sbjct: 152 KKTRAINEKE-AFECIYDSRTRSAGKDIVSVKINIDKAKKILN 193
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 60.1 bits (145), Expect = 8e-13 Identities = 61/263 (23%), Positives = 108/263 (41%), Gaps = 29/263 (11%) Query: 4 LKGKKGLIVGVANNKSIAYGIAQSCFNQGATL-AFTYLNESLEKRVRPIAQELNSPYVYE 62 ++GK I G A + I +A++ +QGA + A Y E LEK V + E + Sbjct: 6 IEGKIAFITGAA--QGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 LDVSKEEHFKSLYNNIKKDLGSLDFIVHSVAF--------APKEALEGSLLETSKSAFNT 114 DV + I++++G +D +V+ E E + S FN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 115 AMEISVYSLIELTNTLKPLLNNGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAV 174 + +S Y + + ++ + +N A V S MA Y +KAA + L + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTS-------MAAY---ASSKAAAVMFTKCLGL 173 Query: 175 DLGRHHIRVNALSAGPIRT-----LASSGIADFRMILKWNE---INAPLRKNVSLEEVGN 226 +L ++IR N +S G T L + ++I E PL+K ++ + Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 227 AGMYLLSSLSNGVSGEVHFVDAG 249 A ++L+S + ++ VD G Sbjct: 234 AVLFLVSGQAGHITMHNLCVDGG 256
>PF01540#Adhesin lipoprotein Length = 475 Score = 33.9 bits (77), Expect = 0.003 Identities = 32/127 (25%), Positives = 60/127 (47%), Gaps = 10/127 (7%) Query: 209 IGKGKQKQLSKIYSHF-KKLSEGEIKPQNEGILKKLKSLDEIFKTTDFTRFTPKTEIKDI 267 + K K+L++I + KKL+E K +N G+ + K +E F+ + + Sbjct: 340 VKKAWSKELAEIKAEDDKKLAEENQKIKN-GVEELKKINNEAFELSK--------TVNKT 390 Query: 268 IKEIDEKYPINENFKRQFRTFRSSIGNLKKKINSLKYLEKTREDFERKKESWIKEIGNDC 327 I E+++K+ I+ +FK Q + F + + ++I+ + T+E F + KEI Sbjct: 391 IAELEKKFKIDVSFKEQLKNFADDLLDKSRQIDEFTTVTSTQEGFTLAELESFKEITTTW 450 Query: 328 KNECNSE 334 N SE Sbjct: 451 FNGMKSE 457 Score = 33.6 bits (76), Expect = 0.004 Identities = 26/124 (20%), Positives = 50/124 (40%), Gaps = 8/124 (6%) Query: 211 KGKQKQLSKIYSHFKKLSEGEIKPQNEGILKKLKSLDEIFKTTDFTRFTPKTEIKDIIKE 270 K K+L++I + K E + EG + LK ++I D I I + Sbjct: 221 KAWSKELAEIKAEDDKKLAEENQKIKEGAKELLKLSEKIQSFAD--------TIALTITK 272 Query: 271 IDEKYPINENFKRQFRTFRSSIGNLKKKINSLKYLEKTREDFERKKESWIKEIGNDCKNE 330 ++ K+ I+E FK+Q + + ++ + + ++DF + KE + Sbjct: 273 LERKFQIDEKFKKQLISTIELLNKKSVEVKTFATVNTIKKDFLLSELESFKEFNTSWLEK 332 Query: 331 CNSE 334 SE Sbjct: 333 IVSE 336
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.4 bits (71), Expect = 0.006 Identities = 36/193 (18%), Positives = 77/193 (39%), Gaps = 1/193 (0%) Query: 23 VLIPLLILSGSLTPHQSFQLGIAVLMGYVFGSFLIQFLSPLMSLESIAKISFGLIALSFL 82 V +P + + P + + A ++ + G+ + LS + ++ + + + Sbjct: 35 VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94 Query: 83 VCYFDSIPFFWLWIWRFIAGVASSALMILVAPLSLPYVKEHKKALVGGLIFSAVGIGSVF 142 + + F L + RFI G ++A LV + Y+ + + GLI S V +G Sbjct: 95 IGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154 Query: 143 SGFVLPWISSYNIKWAWIFLGGSCLIAFILSLVGLKTRSLRKKSVKKEESAFKIPFHLWL 202 + I+ Y I W+++ L I + L+ L + +R K + + + Sbjct: 155 GPAIGGMIAHY-IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213 Query: 203 LLISCALNAIGFL 215 ++ +I FL Sbjct: 214 FMLFTTSYSISFL 226
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.011 Identities = 9/18 (50%), Positives = 11/18 (61%) Query: 8 LILSGPSGAGKSTLTKYL 25 ++L G G GKSTL L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.5 bits (128), Expect = 5e-10 Identities = 34/154 (22%), Positives = 63/154 (40%), Gaps = 4/154 (2%) Query: 148 EALAKEEPNNEEQLLPTLNEQEGETPKEEAQEEVKKEEVKEMQ-EEVKEMQEEVKEKQKQ 206 E +A+ + P + ET E +++E K E E E EV ++ K Sbjct: 1015 EEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKS 1074 Query: 207 EVAENPQDEEKPKDDETQGSVEPPKDEEVSKELETQEQEPIKEETQEIKEEKQEKTQDSP 266 V N Q E ++ + + E + +++E K ET++ +E + +Q SP Sbjct: 1075 NVKANTQTNEV---AQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSP 1131 Query: 267 NVQELEAMQELVKEIQENSNDQENKKPKKPKKTQ 300 ++ E +Q + +EN K+P+ T Sbjct: 1132 KQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT 1165 Score = 45.4 bits (107), Expect = 2e-07 Identities = 30/128 (23%), Positives = 46/128 (35%), Gaps = 4/128 (3%) Query: 167 EQEGETPKEEAQEEVKKEEVKEMQEEVKEMQEEVKEKQKQEVAENPQDEEKPKDDETQGS 226 E + +EE K E ++ QE K + +V KQ+Q PQ E ++D T Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 227 VEPPKDEEVSKELETQEQEPIKEETQEIKEEKQEKTQDSPNVQELEAMQELVKEIQENSN 286 EP + + E +E Q + E T +S Q N Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE---NTTPATTQPTVN 1212 Query: 287 DQENKKPK 294 + + KPK Sbjct: 1213 SESSNKPK 1220 Score = 44.3 bits (104), Expect = 5e-07 Identities = 21/147 (14%), Positives = 54/147 (36%), Gaps = 4/147 (2%) Query: 151 AKEEPNNEEQ-LLPTLNEQEGETPKEEAQEEVKKEEVKEMQEEVKEMQEE---VKEKQKQ 206 KE E++ E+ E PK +Q K+E+ + +Q + + +E V K+ Q Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 207 EVAENPQDEEKPKDDETQGSVEPPKDEEVSKELETQEQEPIKEETQEIKEEKQEKTQDSP 266 D E+P + + +P + + + P + ++ + P Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKP 1219 Query: 267 NVQELEAMQELVKEIQENSNDQENKKP 293 + +++ + ++ + ++ Sbjct: 1220 KNRHRRSVRSVPHNVEPATTSSNDRST 1246 Score = 31.2 bits (70), Expect = 0.005 Identities = 25/122 (20%), Positives = 41/122 (33%), Gaps = 3/122 (2%) Query: 111 QKKLGSNMSELEPSQNSDPTQEILETNWDELENLGDLEALAKEEPNNEEQLLPTLNEQEG 170 Q++ + + EP++ +DPT I E + D E AKE +N EQ + Sbjct: 1133 QEQSETVQPQAEPARENDPTVNIKEPQ-SQTNTTADTEQPAKETSSNVEQPVTESTTVNT 1191 Query: 171 ETPKEEAQEEVKKEEVKEMQEEVKEMQEEVKEKQKQEVAENPQDEEKPKDDETQGSVEPP 230 E E + E + K + ++ V P + E S Sbjct: 1192 GNSVVENPENTTPATTQP--TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVAL 1249 Query: 231 KD 232 D Sbjct: 1250 CD 1251
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 194 bits (495), Expect = 1e-64 Identities = 52/172 (30%), Positives = 84/172 (48%), Gaps = 18/172 (10%) Query: 56 GERPLFADRRAMKPNDLITIIVSEKASANYSSS----KDYKSASGGNSTPPRLTYNGLDE 111 G +PLF DRR D +TI++ E SA+ SSS +D K+ G ++ P L GL Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYL--QGLFG 118 Query: 112 RKKKEAEYLDDKNNYNFTKSSNNTNFKGGGSQKKSEDLEIVLSARIIKVLENGNYFIYGN 171 + + E S F G G S L+ + +VL NGN + G Sbjct: 119 NARADVEA------------SGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGE 166 Query: 172 KEVLVDGEKQILKVSGVIRPYDIERNNTIQSKFLADAKIEYTNLGHLSDSNK 223 K++ ++ + ++ SGV+ P I +NT+ S +ADA+IEY G+++++ Sbjct: 167 KQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN 218
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.9 bits (67), Expect = 0.001 Identities = 12/37 (32%), Positives = 20/37 (54%) Query: 22 GVASQTPKELYDLGVESYKAKDYIKAKKYFEKACGLN 58 ++S T ++LY L Y++ Y A K F+ C L+ Sbjct: 30 EISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLD 66
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.009 Identities = 12/32 (37%), Positives = 17/32 (53%) Query: 30 VVALLGESGAGKSTILRILAGLEAVSSGYIEA 61 V L G G GKST++ L GL+ S + + Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 198 bits (505), Expect = 1e-57 Identities = 116/461 (25%), Positives = 190/461 (41%), Gaps = 67/461 (14%) Query: 3 NIRNIAVIAHVDHGKTTLVDGLLSQSGTFSEREKVDE--RVMDSNDLERERGITILSKNT 60 I NI V+AHVD GKTTL + LL SG +E VD+ D+ LER+RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 61 AIYYKDTKINIIDTPGHADFGGEVERVLKMVDGVLLLVDAQEGVMPQTKFVVKKALSFGI 120 + +++TK+NIIDTPGH DF EV R L ++DG +LL+ A++GV QT+ + GI Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 121 CPIVVVNKIDKPAAEPDRVVDEVFDLF---------VAMGASDKQLDFPV-----VYAAA 166 I +NKID+ + V ++ + V + + +F Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 167 RDGYAMKSLDDE----------------------------KKNL--EPLFETILEHVPSP 196 D K + + K N+ + L E I S Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSS 241 Query: 197 SGSVDEPLQMQIFTLDYDNYVGKIGIARVFNGSVKKNESVLLMKSDGSKENGRITKLIGF 256 + L ++F ++Y ++ R+++G + +SV + KE +IT++ Sbjct: 242 THRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRI----SEKEKIKITEMYTS 297 Query: 257 LGLARTEIENAYAGDIVALAG--FNAMDV-GDSVVDPTNPMPLDPMHLEEPTMSVYFAVN 313 + +I+ AY+G+IV L V GD+ + P +P P + + Sbjct: 298 INGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENP----LPLLQTTVEPS 353 Query: 314 DSPLAGLEGKHVTANKLKDRLLKEMQTNIAMKCEEMGEGKFKVSGRGELQITILAENLRR 373 + + D LL+ + + +S G++Q+ + L+ Sbjct: 354 KPQQREMLLDALLEISDSDPLLRYYVDSAT--------HEIILSFLGKVQMEVTCALLQE 405 Query: 374 E-RFEFSISRPEVIIKEENGVKCEPFEHLVIDTPQDFSGAI 413 + E I P VI E K E H+ + P F +I Sbjct: 406 KYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445 Score = 41.8 bits (98), Expect = 8e-06 Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 396 EPFEHLVIDTPQDFSGAIIERLGKRKAEMKAMNPMSDGYTRLEFEIPARGLIGYRSEFLT 455 EP+ I PQ++ K A + + + L EIPAR + YRS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595 Query: 456 DTKGEGVMNHSFLEFRPFSG 475 T G V + +G Sbjct: 596 FTNGRSVCLTELKGYHVTTG 615
>PF03944#delta endotoxin Length = 633 Score = 31.2 bits (70), Expect = 0.005 Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 68 LHHQEKLLNQCMLSQALKAMGDAELRVFLASVHDDLKGYEEFLSLCQKPHILALSKIDTA 127 L E+ LNQ + + + A +AEL A+V + + + FL+ + L+++ Sbjct: 94 LRETERFLNQRLNTDTV-ARVNAELTGLQANVEEFNRQVDNFLNPNRNAVPLSITSSVNT 152 Query: 128 THKQVLQKLQEYQKYASQFLDLVPLSAKKSQNLN 161 + L +L ++Q Q L L+PL A+ + NL+ Sbjct: 153 MQQLFLNRLPQFQMQGYQLL-LLPLFAQAA-NLH 184
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 789 bits (2038), Expect = 0.0 Identities = 479/482 (99%), Positives = 482/482 (100%) Query: 1 MVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWNIVPNSNHIFIQPK 60 +VNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGW+IVPNSNHIFIQPK Sbjct: 41 VVNKKIAYLGDEKPITIWTSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPK 100 Query: 61 SVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK 120 SVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK Sbjct: 101 SVKSNLMFEKEAVNFALMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQK 160 Query: 121 AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDM 180 AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDM Sbjct: 161 AQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLEDM 220 Query: 181 QEQAQANALKQIEELNKKQAEEAVKQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTN 240 QEQAQANALKQIEELNKKQAEEAV+QRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTN Sbjct: 221 QEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSAWRTN 280 Query: 241 LVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELI 300 LVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELI Sbjct: 281 LVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEELKKREEAKRQRELI 340 Query: 301 KQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN 360 KQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN Sbjct: 341 KQENLNTTAYINRVMMASNEQIINKEKIREEKQKIILDQAKALETQYVHNALKRNPVPRN 400 Query: 361 YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMT 420 YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMT Sbjct: 401 YNYYQAPEKRSKHIMPSEIFDDGTFTYFGFKNITLQPAIFVVQPDGKLSMTDAAIDPNMT 460 Query: 421 NSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVR 480 NSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVR Sbjct: 461 NSGLRWYRVNEIAEKFKLIKDKALVTVINKGYGKNPLTKNYNIKNYGELERVIKKLPLVR 520 Query: 481 DK 482 DK Sbjct: 521 DK 522
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 119 bits (299), Expect = 5e-35 Identities = 44/205 (21%), Positives = 74/205 (36%), Gaps = 10/205 (4%) Query: 27 KLNKANRTFKRAFYL---SMALNVAAVTSIVMMMPLKKTDIFVYGIDRYTGEFKIVKRSD 83 KL A R+ K A+ + + AL A V ++ + PLK + +V +DR TGE I + Sbjct: 24 KLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLH 83 Query: 84 A-RQIVNSEAVVDSATSKFVSLLFGYSKNSLRDRKDQLMQYCDVSFQTQAMRMFNENIRQ 142 I EAV + +V G+ + + D +M Q + R + + Q Sbjct: 84 GDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDNPQ 143 Query: 143 FVDKVRA-EAIISSNIQREKVKNSPLTRLTFFITIKITPDTMENYEYITKKQVTIYYDFA 201 + A + I + +F +T T TI Y Sbjct: 144 SPQNILANRTDVFVEI-KRVSFLGGNVAQVYFTKESVTGSNS----TKTDAVATIKYKVD 198 Query: 202 RGNSSQENLIINPFGFKVFDIQITD 226 S + + NP G++V + Sbjct: 199 GTPSKEVDRFKNPLGYQVESYRADV 223
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 29.8 bits (66), Expect = 0.015 Identities = 29/119 (24%), Positives = 54/119 (45%), Gaps = 16/119 (13%) Query: 24 AINTALLPSEYKELVALGFKKIKTFYQRHDDKEITKEEKEFATNALREKLRNDRARAEQI 83 A+N AL+ +Y+E + K K D KE+ +++K EK + + +A++ Sbjct: 112 AVNFALMTRDYQEFL----KTKKLIVDAPDPKELEEQKKAL------EKEKEAKEQAQKA 161 Query: 84 QKNIEAFEKKNNSSVQKKAAKHRGLQELNETNANPLNDNPNGNSPTETKSNKDDNFDEM 142 QK+ K +++A L+ L +NP N + N N K +++ D+M Sbjct: 162 QKD------KREKRKEERAKNRANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQM 214
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.1 bits (73), Expect = 0.015 Identities = 20/88 (22%), Positives = 32/88 (36%), Gaps = 18/88 (20%) Query: 19 EVQKRQFQKIEELKADMQKGINPFFKVLFDGGNRLFGFPETFIYSSI-------FILFVT 71 + K K+ EL+ +G+ +D F+ SI F + Sbjct: 301 DTAKAIKAKLAELQPFFPQGMK--VLYPYD--------TTPFVQLSIHEVVKTLFEAIML 350 Query: 72 IVLSVILF-QAYEPVLIVAIVIVLVALG 98 + L + LF Q LI I + +V LG Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLG 378
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 1868 bits (4841), Expect = 0.0 Identities = 1041/1187 (87%), Positives = 1084/1187 (91%), Gaps = 43/1187 (3%) Query: 1 MTNETIDQQPQTEAAFNPQQFINNLQVAFLKVDNAIASFDPDQKPIVDKNDRDNRQAFDG 60 MTNETIDQQPQTEAAFNPQQFINNLQVAFLKVDNA+AS+DPDQKPIVDKNDRDNRQAF+G Sbjct: 1 MTNETIDQQPQTEAAFNPQQFINNLQVAFLKVDNAVASYDPDQKPIVDKNDRDNRQAFEG 60 Query: 61 ISQLREEYSNKAIKNPTKKNQYFSDFINKSSDLINKDNLIDVESSTKSFQKFGDQRYRIF 120 ISQLREEYSNKAIKNPTKKNQYFSDFINKS+DLINKDNLIDVESSTKSFQKFGDQRYRIF Sbjct: 61 ISQLREEYSNKAIKNPTKKNQYFSDFINKSNDLINKDNLIDVESSTKSFQKFGDQRYRIF 120 Query: 121 TSWVSHQNDPSKINTRSIRNFMEHAIQPPIPDDKEKAEFLKSAKQSFAGIIIGNQIRTDQ 180 TSWVSHQNDPSKINTRSIRNFME+ IQPPI DDKEKAEFLKSAKQSFAGIIIGNQIRTDQ Sbjct: 121 TSWVSHQNDPSKINTRSIRNFMENIIQPPILDDKEKAEFLKSAKQSFAGIIIGNQIRTDQ 180 Query: 181 KFMGVFDESLKERQEAEKNGGSTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPHVQPDI 240 KFMGVFDESLKERQEAEKNG TGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPHVQPDI Sbjct: 181 KFMGVFDESLKERQEAEKNGEPTGGDWLDIFLSFIFDKKQSSDVKEAINQEPVPHVQPDI 240 Query: 241 ATSTTHIQGLPPESRDLLDERGNFSKFTLGDMEMLDVEGVADMDPNYKFNQLLIHNNALS 300 AT+TT IQGLPPE+RDLLDERGNFSKFTLGDMEMLDVEGVAD+DPNYKFNQLLIHNNALS Sbjct: 241 ATTTTDIQGLPPEARDLLDERGNFSKFTLGDMEMLDVEGVADIDPNYKFNQLLIHNNALS 300 Query: 301 SVLMGSHDGIEPEKVSLLYAGNGGFGDKHDWNATVGYKDQQGNNVATIINVHMKNGSGLI 360 SVLMGSH+GIEPEKVSLLY GNGG G +HDWNATVGYKDQQGNNVATIINVHMKNGSGL+ Sbjct: 301 SVLMGSHNGIEPEKVSLLYGGNGGPGARHDWNATVGYKDQQGNNVATIINVHMKNGSGLV 360 Query: 361 IAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFMEFLAQNNAKLDSLSEKEKEK 420 IAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFMEFLAQNNAKLD+LSEKEKEK Sbjct: 361 IAGGEKGINNPSFYLYKEDQLTGSQRALSQEEIQNKIDFMEFLAQNNAKLDNLSEKEKEK 420 Query: 421 FKNEIKDFQKDSKPYLDALGNDRIAFVSKKDPKHSALITEFNKGDLSYTLKDYGKKADKA 480 F+ EIKDFQKDSK YLDALGNDRIAFVSKKD KHSALITEF GDLSYTLKDYGKKADKA Sbjct: 421 FRTEIKDFQKDSKAYLDALGNDRIAFVSKKDTKHSALITEFGNGDLSYTLKDYGKKADKA 480 Query: 481 LDREKNVTLQGNLKHDGVMFVNYSNFKYTNASKSPNKGVGVTNGVSHLEAGFSKVAVFNL 540 LDREKNVTLQG+LKHDGVMFV+YSNFKYTNASK+PNKGVGVTNGVSHLE GF+KVA+FNL Sbjct: 481 LDREKNVTLQGSLKHDGVMFVDYSNFKYTNASKNPNKGVGVTNGVSHLEVGFNKVAIFNL 540 Query: 541 PNLNNLAITSVVRRDLEDKLIAKGLSPQEANKLVKDFLSSNKELVGKALNFNKAVAEAKN 600 P+LNNLAITS VRR+LEDKL KGLSPQEANKL+KDFLSSNKELVGK LNFNKAVA+AKN Sbjct: 541 PDLNNLAITSFVRRNLEDKLTTKGLSPQEANKLIKDFLSSNKELVGKTLNFNKAVADAKN 600 Query: 601 TGNYDEVKRAQKDLEKSLKKREHLEKDVAKNLESKSGNKNKMEVKSQANSQKDEIFALIN 660 TGNYDEVK+AQKDLEKSL+KREHLEK+V K LESKSGNKNKME K+QANSQKDEIFALIN Sbjct: 601 TGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEIFALIN 660 Query: 661 KEANRDARAIAYAQNLKDIKRELSDKLENISKDLKDFSKSFDEFKNGKSKDFSKVEETLK 720 KEANRDARAIAYAQNLK IKRELSDKLEN++K+LKDF KSFDEFKNGK+KDFSK EETLK Sbjct: 661 KEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDFDKSFDEFKNGKNKDFSKAEETLK 720 Query: 721 ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSIKDVIINQKI 780 ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENS+KDVIINQK+ Sbjct: 721 ALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDVIINQKV 780 Query: 781 TDKVDNLNQAVSMAKIAGNFSGVEQALADLKNFSKEQLAQQAQKNESFNVGK-SEIYQSV 839 TDKVDNLNQAVS+AK G+FS VEQALADLKNFSKEQLAQQAQKNES N K SEIYQSV Sbjct: 781 TDKVDNLNQAVSVAKATGDFSRVEQALADLKNFSKEQLAQQAQKNESLNARKKSEIYQSV 840 Query: 840 KNGVNGTLVGNGLSGIEATALAKNFSDIKKELNEKFKNFNNNNNGLKNGKDKGPEEPIYA 899 KNGVNGTLVGNGLS EAT L+KNFSDIKKELN K NFNNNNN EPIYA Sbjct: 841 KNGVNGTLVGNGLSQAEATTLSKNFSDIKKELNAKLGNFNNNNNNGLKN------EPIYA 894 Query: 900 QVNKKKTGQVASPEEPIYAQVAKKVTQKIDQLNQAASGFGGVGQ-AGFPLKRHDKVEDLS 958 +VNKKK GQ AS EEPIYAQVAKKV KID+LNQ ASG G VGQ AGFPLKRHDK Sbjct: 895 KVNKKKAGQAASLEEPIYAQVAKKVNAKIDRLNQIASGLGVVGQAAGFPLKRHDK----- 949 Query: 959 KVGRSVSPEPIYATIDDLGGSFPLRRSAAVDDLSKVGRSREQELTQKIDNLSQAVSEAKA 1018 VDDLSKVG SR QEL QKIDNL+QAVSEAKA Sbjct: 950 -----------------------------VDDLSKVGLSRNQELAQKIDNLNQAVSEAKA 980 Query: 1019 GFFGNLERTIDKLKDSTKNNPVNLWAENAKKVPASLSAKLDNYATNSHTRINSNIQNGAI 1078 GFFGNLE+TIDKLKDSTK+NP+NLW E+AKKVPASLSAKLDNYATNSH RINSNI+NGAI Sbjct: 981 GFFGNLEQTIDKLKDSTKHNPMNLWVESAKKVPASLSAKLDNYATNSHIRINSNIKNGAI 1040 Query: 1079 NEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTKLN 1138 NEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTKLN Sbjct: 1041 NEKATGMLTQKNPEWLKLVNDKIVAHNVGSVPLSEYDKIGFNQKNMKDYSDSFKFSTKLN 1100 Query: 1139 NAVKDVKSGFTQFLANAFSTG-YYSLARENAEHGIKNANTKGGFQKS 1184 NAVKD SGFTQFL NAFST YY LARENAEHGIKN NTKGGFQKS Sbjct: 1101 NAVKDTNSGFTQFLTNAFSTASYYCLARENAEHGIKNVNTKGGFQKS 1147
>SECA#SecA protein signature. Length = 901 Score = 27.9 bits (62), Expect = 0.014 Identities = 12/43 (27%), Positives = 23/43 (53%), Gaps = 2/43 (4%) Query: 71 RIARKNLSKMSEEDFKKMREEVRK--ELEEKTKGLSDEEIKAK 111 ++ K ++ ++MR+ V +E + + LSDEE+K K Sbjct: 4 KLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGK 46
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 39.4 bits (92), Expect = 2e-05 Identities = 38/176 (21%), Positives = 66/176 (37%), Gaps = 12/176 (6%) Query: 211 AASIATLSNDERELGVACVDMGGETCNLTIYSGNSIRYNKYLPVGSHHLTTDL------S 264 AA+I G VD+GG T + + S N + Y+ + +G + + Sbjct: 146 AAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRN 205 Query: 265 HMLNTPFPYAEEVKIKYGDLSFESGTETPSQSVQIPTTGSDGNESHIVPLSEIQTIMRER 324 + AE +K + G S G E V+ + +EI ++E Sbjct: 206 YGSLIGEATAERIKHEIG--SAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEP 263 Query: 325 ALETFKIIHRSIQDSGLE---EHLGGGVVLTGGMALMKGIKELARTHFTNYPVRLA 377 + +++ E + G+VLTGG AL++ + L T PV +A Sbjct: 264 LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLM-EETGIPVVVA 318
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.022 Identities = 28/150 (18%), Positives = 51/150 (34%), Gaps = 26/150 (17%) Query: 52 SQVEANTQAQEGLRSVYEGQANKIKDLNNAILSQEESLRALKASQEVQANTLKQQSQTLE 111 + + Q + SV + + + + + E A KQ+S+T+E Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS--ETTETVAENSKQESKTVE 1052 Query: 112 DLRNEIRANQQAIQQLDKQNKEMSELLTKLSQDLVSQIALIQKALKEQEEKAEKPLKSSA 171 +NE A + Q + + S + + V+Q E +E Sbjct: 1053 --KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGS------ETKETQTT------ 1098 Query: 172 PANKNPPLKAETTKNQEKKTQEKAKVEFDK 201 ET + + +EKAKVE +K Sbjct: 1099 ----------ETKETATVEKEEKAKVETEK 1118
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 136 bits (345), Expect = 4e-42 Identities = 46/162 (28%), Positives = 71/162 (43%), Gaps = 24/162 (14%) Query: 2 AGDVSAKTVQTAPV-TTEPAPEKEEPKQEPAPVVEEKPAIESGTIIASIYFDFDKYEIKE 60 + VS + Q PAP PAP V+ K T+ + + F+F+K +K Sbjct: 184 SLGVSYRFGQGEAAPVVAPAPA-------PAPEVQTK----HFTLKSDVLFNFNKATLKP 232 Query: 61 SDQETLDEIVQKAKE---NHMQVLLEGNTDEFGSSEYNQALGVKRTLSVKNALVIKGVEK 117 Q LD++ + V++ G TD GS YNQ L +R SV + L+ KG+ Sbjct: 233 EGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPA 292 Query: 118 DMIKTISFGETKPKCVQ-----KTR----ECYRENRRVDVKL 150 D I GE+ P K R +C +RRV++++ Sbjct: 293 DKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 32.4 bits (73), Expect = 0.002 Identities = 36/139 (25%), Positives = 64/139 (46%), Gaps = 12/139 (8%) Query: 32 KEAEKILLDLNKKDEQAID--LNLEDLPSEKKNE-KIEKVTEKQGDF---LEPKEEPKEE 85 +EA K++ D +++ + LN ++ KN ++V + Q D L +E ++E Sbjct: 568 QEANKLIKDFLSSNKELVGKTLNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKE 627 Query: 86 PEESLEDIFSSLNDFQEKTDKNAQKDE-----QKNEQEEQRRLREQQRLKQ-NQENQEML 139 E+ LE + N + K N+QKDE K + R + Q LK +E + L Sbjct: 628 VEKKLESKSGNKNKMEAKAQANSQKDEIFALINKEANRDARAIAYAQNLKGIKRELSDKL 687 Query: 140 KGLQQNLNQFTQKLESVKN 158 + + +NL F + + KN Sbjct: 688 ENVNKNLKDFDKSFDEFKN 706
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 33.0 bits (75), Expect = 0.001 Identities = 12/33 (36%), Positives = 20/33 (60%) Query: 72 EPEVQILKDLKPDFIVVVAYGKILPKEVLAIAP 104 EP +++L ++KP F+V A P+ + IAP Sbjct: 86 EPNLELLTEMKPSFMVWSAGYGPSPEMLARIAP 118
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 23.6 bits (51), Expect = 0.032 Identities = 7/13 (53%), Positives = 10/13 (76%) Query: 5 FYKELKMDKQKVK 17 + KELKM K ++K Sbjct: 210 YIKELKMSKDEIK 222
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.4 bits (68), Expect = 0.002 Identities = 17/50 (34%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 32 MEEIENSDPNQNNPFITA--AMGIGGAAISIFFPNTKPIVDGIKPLAEKG 79 ME I NPFI+A A+GIG + K + I PL +G Sbjct: 225 MEFINGVAAGALNPFISAGEALGIGDILYGTRYAIDKAAMRNIAPLPAEG 274
>PF05844#YopD protein Length = 295 Score = 24.6 bits (53), Expect = 0.039 Identities = 12/65 (18%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 10 SVLKANNPHFDKIFEKHNQLDDDIKTAEQQNASDAEVSHMKKQKLKLKDEIHSMIIEYRE 69 L+A F+ + I++ Q + +V + Q ++E+++ I + + Sbjct: 197 VALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQASAREEEVNATIGQ-SQ 255 Query: 70 KQKSD 74 KQK + Sbjct: 256 KQKVE 260
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 48.8 bits (116), Expect = 4e-10 Identities = 25/84 (29%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Query: 1 MTSALLGLQIVLAVLIVVVVLLQ--KSSSIGLGAYSGSNDSLFGAKGPASFMAKLTMFLG 58 M ALL + +++A+ +V +++LQ K + +G +G++ +LFG+ G +FM ++T L Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 59 LLFVINTIALGYFYNKEYGKSVLD 82 LF I ++ LG N + Sbjct: 61 TLFFIISLVLGNI-NSNKTNKGSE 83
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 28.6 bits (64), Expect = 0.024 Identities = 11/74 (14%), Positives = 19/74 (25%), Gaps = 5/74 (6%) Query: 83 TPIKKSTTIIDLGGAKAQILHNIPKSIRKNFIAAHPMCGTEFYGPKASVKGLYENALVIL 142 P + L GA + ++RK + Y L Sbjct: 18 APAVEGDVSFRLSGATSSSYGVFISNLRKALPYERKLYDIPLLRSTLPGSQRY-----AL 72 Query: 143 CDLEDSGTEQVEIA 156 L + E + +A Sbjct: 73 IHLTNYADETISVA 86
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 225 bits (574), Expect = 9e-79 Identities = 63/147 (42%), Positives = 93/147 (63%) Query: 4 IGIYPGTFDPVTNGHIDIIHRSSELFEELIVAVAHSSAKNPMFSLDERLKMMQLATKSFK 63 IYPG+FDP+T GH+DII R LF+++ VAV + K PMFS+ ERL+ + A Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61 Query: 64 NVECVAFEGLLANLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQ 123 N + +FEGL N A++ ++RGLRV+SDFE ELQM NK+L +LET++ + + Sbjct: 62 NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTE 121 Query: 124 NAFISSSIVRSIIAHKGDASHLVPEEI 150 +F+SSS+V+ + G+ H VP + Sbjct: 122 YSFLSSSLVKEVARFGGNVEHFVPSHV 148
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 5e-04 Identities = 9/51 (17%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 127 TVYEIAKKVAQSDTPPYNPVLFYGGTGLGKTHILNAIGNHALEKHKKVVLV 177 +Y + ++ Q+D ++ G +G GK + A+ ++ ++ V + Sbjct: 148 EIYRVLARLMQTDLT----LMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 112 bits (282), Expect = 6e-29 Identities = 72/358 (20%), Positives = 141/358 (39%), Gaps = 25/358 (6%) Query: 97 AKDLAYKSETFILRLEMIPKKANLMILDQEKCVIEA--FRFNDRVAKNDILGALPPNIYE 154 + ++ ++ + + L + K + + I++ F FN N +G N+ Sbjct: 209 SSEICFRLKNNSIDLSLSNLKEIVEVCKDLFKEIQSNKFEFNCYTKNNSFVGFYCLNLMS 268 Query: 155 HQEEDLDFKDLLDILEKDFLSYQ--HKELEHKKNQIIKRLNAQKERLKEKLEKLEDPKNL 212 ++ D L ++F + L+ K + + K + R +K + L + Sbjct: 269 KEDYKKIQYDSSSKLLENFYYAKDKSDRLKSKSSDLQKIVMNNINRCTKKDKILNNTLKK 328 Query: 213 QLEAKELQTQASLLLTYQHLIHKHESCVILKDFED---KECMIEIDKSMPLNAFINKKFT 269 + + LL + + K S + L ++ I +D++ + + + Sbjct: 329 CEDKDIFKLYGELLTANIYALKKGLSHIELANYYSENYDTVKITLDENKTPSQNVQSYYK 388 Query: 270 LSKKKKQKSQFLYLEEENLKEKIAFKENQINYVRDAAEESVLE------------MFMPV 317 K K+ + + +E++ + + + + +A +E F + Sbjct: 389 KYNKLKKSEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKKELIETGYIKFKKI 448 Query: 318 KNSKIKRPMNGYEVLYYKDFKIGLGKNQKENIKL-LQDARANDLWMHVRNIPGSHLIVFC 376 SK + + I +GKN +N L L+ A +D+W H +NIPGSH+IV Sbjct: 449 YKSKKSKTSKPMHFISKDGIDIYVGKNNIQNDYLTLKFANKHDIWFHTKNIPGSHVIVKN 508 Query: 377 QKNTPKDEIILELAKMLIKMQKDAFNS-YEIDYTQRKFVKIIKGAN---VIYSKYRTI 430 + P + +LE A + K +S +DYT+ K VK GA VIYS +TI Sbjct: 509 IMDIP-ESTLLEAANLAAYYSKSQNSSNVPVDYTEVKNVKKPNGAKPGMVIYSTNQTI 565 Score = 35.2 bits (81), Expect = 5e-04 Identities = 19/92 (20%), Positives = 48/92 (52%), Gaps = 5/92 (5%) Query: 46 SAPYIGLSKKPPESVLKNTLALDFCLNKFTKNAKILQANVIDNDRI--LEIKGAKDLAYK 103 + P I L+ + +K + L K+ NAKI+ + I+ DRI ++ + +L + Sbjct: 55 NYPRIHLTDLTKPNPIKAPMFCMV-LRKYISNAKIVDIHQINQDRIVVIDFESTDELGFN 113 Query: 104 SETFILRLEMIPKKANLMILD-QEKCVIEAFR 134 S L +E++ + +N+ ++ ++ ++++ + Sbjct: 114 SIY-SLIIEIMGRHSNMTLIRKRDNIIMDSIK 144
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 133 bits (335), Expect = 2e-40 Identities = 36/202 (17%), Positives = 72/202 (35%), Gaps = 4/202 (1%) Query: 40 QSVFRLERNRLKIAYRLLGLMSFIALVLAIVLISILPLQKTEHHF--VDFLNQDKHYAII 97 + K+A+ + G+ +A + + ++ PL+ E + VD + A Sbjct: 22 RDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAK 81 Query: 98 QRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKAQN 157 D +I+ +EA+ + + YV RE + ++ V + S+ R+ K N Sbjct: 82 LHGDATITYDEAVRKYFLATYVRYREGWIAAAREEYFDAVMVMSARPEQDRWSRFYKTDN 141 Query: 158 SIYAQSHLEREVHI-VNIAIYQQDNNPIASVSIAAKLLNENKLVYEKRYKIVLSYLFDTP 216 Q+ L + V I +A V + + + + + Y D Sbjct: 142 PQSPQNILANRTDVFVEIKRVSFLGGNVAQVYFTKESVTGSNST-KTDAVATIKYKVDGT 200 Query: 217 DFDYASMPKNPTGFKITRYSIT 238 KNP G+++ Y Sbjct: 201 PSKEVDRFKNPLGYQVESYRAD 222
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 32.1 bits (72), Expect = 0.003 Identities = 27/70 (38%), Positives = 37/70 (52%), Gaps = 8/70 (11%) Query: 200 KEKEEETIIIGDNTNAMKIIKKDIQKGYKALKSSQ--RKWYCLWACSKKSKLSLMPKEIF 257 K +EE+ II D A+ + Q + ALK + R + A K+SK +MP EIF Sbjct: 367 KIREEKQKIILDQAKAL-----ETQYVHNALKRNPVPRNYNYYQAPEKRSK-HIMPSEIF 420 Query: 258 NDKQFTYFKF 267 +D FTYF F Sbjct: 421 DDGTFTYFGF 430
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.8 bits (215), Expect = 1e-22 Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 19/180 (10%) Query: 7 LITGVTGQDGSYLAEYLLNLGYEVHGLKRRSSSINTSRIDHLYEDLHSEHKRRFFLHYGD 66 L+TG G G ++++ LL G++V G+ + + S E L F H D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP---GFQFHKID 60 Query: 67 MTDSSNLIHLIATTKPTEIYNLAAQSHVKVSFETPEYTANADGIGTLRILEAMRILGLEK 126 + D + L A+ ++ + V+ S E P A+++ G L ILE R ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 127 KTRFYQASTSELYGEVLETPQNENTPF-------NPRSPYAVAKMYAFYITKNYREAYNL 179 AS+S +YG N PF +P S YA K + Y Y L Sbjct: 120 --HLLYASSSSVYGL------NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGL 171
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.1 bits (112), Expect = 4e-08 Identities = 52/353 (14%), Positives = 107/353 (30%), Gaps = 68/353 (19%) Query: 5 ILITGAYGMVGQNTALYFKKNKPDV-----------TLLTPKKSELY-----------LL 42 L+TGA G +G + + + V L + EL L Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 43 DKDNVQAYLKEYKPTGIIHCAGRVGGIVANMNDLSTYMVENLLMGLYLFSSALDLGVKKA 102 D++ + + R + ++ + Y NL L + ++ Sbjct: 63 DREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 103 INLASSCAYPKYAPNPLKESDLLNGSLEPTNEGYALAKLSVMKYCEYMSTEKGVFYKTLV 162 + +SS Y P D ++ + YA K + S G+ L Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLPATGLR 177 Query: 163 PCNLYGE-------FDKFEEKIAHMIPGLIARMHTAKLKGEKNFAMWGDGTARREYLNAK 215 +YG KF + + L+G+ ++ G +R++ Sbjct: 178 FFTVYGPWGRPDMALFKFTKAM---------------LEGKS-IDVYNYGKMKRDFTYID 221 Query: 216 DLARFIALAYENIAQIPS-----------------VMNVGSGVDYSIEEYYEKVAQVLDY 258 D+A I + I + V N+G+ + +Y + + L Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI 281 Query: 259 KGVFVKDLSKPVGMQQKLMDISK-QKALKWELEIPLEQGIKEAYEYYLKLLEV 310 + +P + + D + + + E ++ G+K +Y +V Sbjct: 282 EAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYKV 334
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 149 bits (377), Expect = 3e-49 Identities = 38/140 (27%), Positives = 75/140 (53%), Gaps = 1/140 (0%) Query: 5 EILKHLQADAIVLFMKVHNFHWNVKGTDFFNVHKATEEIYEEFADMFDDLAERIVQLGHH 64 L ++ +L+ K+H FHW VKG FF +H+ EE+Y+ A+ D +AER++ +G Sbjct: 15 NSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERLLAIGGQ 74 Query: 65 PLVTLSEALKLTRVKEETKTSFHSKDIFKEILGDYKYLEKEFEELSNTAEKEGDKVTVTY 124 P+ T+ E + + + + + ++ + ++ DYK + E + + AE+ D T Sbjct: 75 PVATVKEYTEHASITDGGNET-SASEMVQALVNDYKQISSESKFVIGLAEENQDNATADL 133 Query: 125 ADDQLAKLQKSIWMLEAHLA 144 + +++K +WML ++L Sbjct: 134 FVGLIEEVEKQVWMLSSYLG 153
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.015 Identities = 10/71 (14%), Positives = 25/71 (35%), Gaps = 13/71 (18%) Query: 281 IVLQNFLYNAIDAIEALEESEQ-GQVKIEAFIQNEFIVFTIIDNGKEVENKSALFEPFET 339 +++Q + N I + + Q G++ ++ N + + + G + Sbjct: 258 MLVQTLVENGI--KHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK------- 308 Query: 340 TKLKGNGLGLA 350 + G GL Sbjct: 309 ---ESTGTGLQ 316
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 363 bits (934), Expect = e-127 Identities = 118/345 (34%), Positives = 192/345 (55%), Gaps = 26/345 (7%) Query: 19 AEKIGDIASVVGVRDNQLIGYGLVIGLNGTGDK-SGSKFTMQSISNMLESVNVKISADDI 77 +I DIAS+ RDNQLIGYGLV+GL GTGD S FT QS+ ML+++ + Sbjct: 28 TSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRAMLQNLGITTQGGQS 87 Query: 78 KSKNVAAVMITASLPPFARQGDKIDIHISSIGDAKSIQGGTLVMTPLNAVDGNIYALAQG 137 +KN+AAVM+TA+LPPFA G ++D+ +SS+GDA S++GG L+MT L+ DG IYA+AQG Sbjct: 88 NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMTSLSGADGQIYAVAQG 147 Query: 138 AIVSGNSS-----------NLLSANIINGATIEREVSYDLFHKNAMTLSLKNPNFKNAIQ 186 A++ S SA + NGA IERE+ + L L+NP+F A++ Sbjct: 148 ALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVNLVLQLRNPDFSTAVR 207 Query: 187 VQNTLNKV----FGNKVAIALDPKTIQITRPERLSMVEFLALVQEIPINYSAKNKIIVDE 242 V + +N +G+ +A D + I + +P + +A ++ + + K++++E Sbjct: 208 VADVVNAFARARYGDPIAEPRDSQEIAVQKPRVADLTRLMAEIENLTVETDTPAKVVINE 267 Query: 243 KSGTIVSGVDIIVHPIVVTSQDITLKITKEP--------LNDSKNTQDLDNNMSLDTAHN 294 ++GTIV G D+ + + V+ +T+++T+ P Q + M++ Sbjct: 268 RTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFSRGQTAVQPQTDIMAMQEGSK 327 Query: 295 TLSSNGKNITIAGVVKALQKIGVSAKGMVSILQALKKSGAISAEM 339 G ++ +V L IG+ A G+++ILQ +K +GA+ AE+ Sbjct: 328 VAIVEGPDLR--TLVAGLNSIGLKADGIIAILQGIKSAGALQAEL 370
>SECA#SecA protein signature. Length = 901 Score = 29.1 bits (65), Expect = 0.050 Identities = 16/63 (25%), Positives = 31/63 (49%), Gaps = 2/63 (3%) Query: 261 IVFTRTKKEADELHQFLASKNYKSTALHGDMDQRDRRSSIMAFKKNDADVLVATDVASRG 320 +V T + ++++ + L K L+ + ++I+A A V +AT++A RG Sbjct: 453 LVGTISIEKSELVSNELTKAGIKHNVLNAKFHANE--AAIVAQAGYPAAVTIATNMAGRG 510 Query: 321 LDI 323 DI Sbjct: 511 TDI 513
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.1 bits (73), Expect = 0.006 Identities = 16/50 (32%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 30 VAIVGESGSGKSSIANLIMRLNPR----FKPHNGEILFETTNLLKESEAF 75 + I GESG+GK +A + R F N + L ESE F Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD---LIESELF 209
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.0 bits (65), Expect = 0.047 Identities = 14/38 (36%), Positives = 18/38 (47%), Gaps = 5/38 (13%) Query: 301 LEGVDAILVPGGFGERGIEGKICAIQRARLEKLPFLGI 338 + GVD I+ G GE G I+ L+ L FLG Sbjct: 320 MGGVDVIVFTAGIGENG-----PEIREFILDGLEFLGF 352
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 548 bits (1413), Expect = 0.0 Identities = 176/582 (30%), Positives = 289/582 (49%), Gaps = 66/582 (11%) Query: 11 VDFFIKLNKKQKIALIAAEVLITALLVFLLLYPFKEKDYAQGGYGVLFERLDSSDNALIL 70 +++ +L +I LI A A++V ++L+ K DY LF L D I+ Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWA-KTPDYR-----TLFSNLSDQDGGAIV 66 Query: 71 QHLQQNQIPYKVLKDD-TILVPKDKVYEERITLASQGIPKTSKVGFEIFDTKDFGATDFD 129 L Q IPY+ I VP DKV+E R+ LA QG+PK VGFE+ D + FG + F Sbjct: 67 AQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQFS 126 Query: 130 QNIKLIRAIEGELSRTIESLNPILKANVHIAIPKDSVFVAKEVPPSASVMLKLKPDMKLS 189 + + RA+EGEL+RTIE+L P+ A VH+A+PK S+FV ++ PSASV + L+P L Sbjct: 127 EQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALD 186 Query: 190 PTQILGIKNLIAAAVPKLTIENVKIVNENGESIGEGDILENSKELALEQLRYKQNFENIL 249 QI + +L+++AV L NV +V+++G + + + + ++L QL++ + E+ + Sbjct: 187 EGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNT--SGRDLNDAQLKFANDVESRI 244 Query: 250 ENKIVNILAPIVGGKNKVVARVNAEFDFSQKKSTKETFDPNN-----VVRSEQNLEEKKE 304 + +I IL+PIVG N V A+V A+ DF+ K+ T+E + PN +RS Q ++ Sbjct: 245 QRRIEAILSPIVGNGN-VHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQV 303 Query: 305 GAPKKQVGGVPGVVSN-IGPVQGLKDNKEPEKYEKSQN---------------------- 341 GA GGVPG +SN P P + +QN Sbjct: 304 GAGYP--GGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNE 361 Query: 342 TTNYEVGKTISEIKGEFGTLVRLNAAVVVDGKYKIAFKDGANALEYEPLSDESLKKINAL 401 T+NYEV +TI K G + RL+ AVVV+ K K PL+ + +K+I L Sbjct: 362 TSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKP-------LPLTADQMKQIEDL 414 Query: 402 VKQAIGYNQNRGDDVAVSNFEFNPMAPMIDNATFSEKIMHKTQKILGSFTPLIKYILVFI 461 ++A+G++ RGD + V N F+ + E + Q + +++LV + Sbjct: 415 TREAMGFSDKRGDTLNVVNSPFSAVDNTGG-----ELPFWQQQSFIDQLLAAGRWLLVLV 469 Query: 462 VLFIFYKKVIVPFSERMLEVVPDEDKEVKSMFEEMDEEEDELNKLGDLRKKVEDQLGLNA 521 V +I ++K + P R +E ++ + E + E L+K L+++ +Q Sbjct: 470 VAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQ----- 524 Query: 522 SFSEEEVRYEIILEKIRGTLKERPDEIATLFKLLIKDEISSD 563 + E++ ++IR E D + L+I+ +S+D Sbjct: 525 -----RLGAEVMSQRIR----EMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 348 bits (895), Expect = e-122 Identities = 121/338 (35%), Positives = 208/338 (61%), Gaps = 4/338 (1%) Query: 8 KQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQIGAAV 67 K+ + L+ +K AILL+ +G + + ++ ++L + I ++ +I +L ++ V Sbjct: 7 KEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNV 66 Query: 68 LEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEARKVMDKLTKSLQTQKNFAYLGKIKP 127 L EF + + ++I GG++YARELL ++LG+++A +++ L +LQ+ + F ++ + P Sbjct: 67 LLEFKELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQS-RPFEFVRRADP 125 Query: 128 QQLADFIINEHPQTIALILAHMEAPNAAETLSYFPDEMKAEISIRMANLGEISPQVVKRV 187 + +FI EHPQTIALIL++++ A+ LS P E++ ++ R+A + SP+VV+ V Sbjct: 126 ANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREV 185 Query: 188 STVLENKLESLTSYK-IEVGGLRAVAEIFNRLGQKSAKTTLARIESVDNKLAGAIKEMMF 246 VLE KL SL+S GG+ V EI N +K+ K + +E D +LA IK+ MF Sbjct: 186 ERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMF 245 Query: 247 TFEDIAKLDNFAIREILKVADKKDLSLALKTSTQDLTDKFLNNMSSRAAEQFVEEMQYLG 306 FEDI LD+ +I+ +L+ D ++L+ ALK+ + +K NMS RAA E+M++LG Sbjct: 246 VFEDIVLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLG 305 Query: 307 AVKIKDVDVAQRKIIEIVQSLQEKG--VIQTGEEEDVI 342 + KDV+ +Q+KI+ +++ L+E+G VI G EEDV+ Sbjct: 306 PTRRKDVEESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343 Score = 31.3 bits (71), Expect = 0.006 Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 3/103 (2%) Query: 4 KLTPKQKAQLDELSMSEKIAILLIQVGEDTTGEILRHLDIDSITEISKQIVQLNGTDKQI 63 + P + + IA++L + IL L + T ++++I ++ T ++ Sbjct: 122 RADPANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEV 181 Query: 64 GAA---VLEEFFAIFQSNQYINTGGLEYARELLTRTLGSEEAR 103 VLE+ A S Y + GG++ E++ E Sbjct: 182 VREVERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKF 224
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 113 bits (284), Expect = 2e-28 Identities = 53/162 (32%), Positives = 87/162 (53%), Gaps = 7/162 (4%) Query: 3 NIRNFSIIAHIDHGKSTLADCLIAECNAIS---NREMTSQVMDTMDIEKERGITIKAQSV 59 I N ++AH+D GK+TL + L+ AI+ + + + D +E++RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 60 RLNYTLKGEDYVLNLIDTPGHVDFSYEVSRSLCSCEGALLVVDATQGVEAQTIANTYIAL 119 + E+ +N+IDTPGH+DF EV RSL +GA+L++ A GV+AQT + Sbjct: 62 SFQW----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 120 DNNLEILPVINKIDLPNANVLEVKQDIEDTIGIDCSSANEVS 161 + + INKID ++ V QDI++ + + +V Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVE 159 Score = 83.8 bits (207), Expect = 5e-19 Identities = 50/215 (23%), Positives = 90/215 (41%), Gaps = 17/215 (7%) Query: 161 SAKAKLGIKDLLEKIITTIPAPSGDPNAPLKALIYDSWFDNYLGALALVRIMDGSINTEQ 220 SAK +GI +L+E I + + + L ++ + LA +R+ G ++ Sbjct: 220 SAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRD 279 Query: 221 EILVMGTGKKHGVLGLYYPNPLKKIPTKSLECGEIGIV---SLGLKSVTDIAVGDTLTDA 277 + + K + +Y + GEI I+ L L SV +GDT Sbjct: 280 SVRISEKEKI-KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV----LGDTKLL- 333 Query: 278 KNPTSKPIEGFMPAKPFVFAGLYPIETDRFEDLREALLKLQLNDCALNFEPESSVALGFG 337 P + IE P + + P + + E L +ALL++ +D L + +S+ Sbjct: 334 --PQRERIEN---PLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATH---E 385 Query: 338 FRVGFLGLLHMEVIKERLEREFGLNLIATAPTVVY 372 + FLG + MEV L+ ++ + + PTV+Y Sbjct: 386 IILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIY 420 Score = 31.0 bits (70), Expect = 0.015 Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 2/75 (2%) Query: 399 IKEPFVRATIITPSEFLGNLMQLLNNKRGIQEKMEYLNQSRVMLTYSLPSNEIVMDFYDK 458 + EP++ I P E+L + L + V+L+ +P+ I ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCI-QEYRSD 592 Query: 459 LKSCTKGYASFDYEP 473 L T G + E Sbjct: 593 LTFFTNGRSVCLTEL 607
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.9 bits (67), Expect = 0.010 Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 3 NGYYAATGAMATQFNRLDLTSNNLANLNTNGFKRDDAITG 42 + A + L+ SNN+++ N G+ R I Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA 41
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.5 bits (92), Expect = 2e-05 Identities = 42/182 (23%), Positives = 71/182 (39%), Gaps = 33/182 (18%) Query: 37 APYFAKEFTHTNDPTLALISAFLVFMLGFFMRPLGSLFFGKLGDKKGRKTSMVYSIILMA 96 P A +F T + +AF++ G+ +GKL D+ G K +++ II+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSI------GTAVYGKLSDQLGIKRLLLFGIIINC 90 Query: 97 LGSFMLALLPTKEIVGEWAFLFLLLARLLQGFSVGGE------YGVVATYLSELGKNGKK 150 GS + VG F L++AR +QG G VVA Y+ + + Sbjct: 91 FGSVIGF-------VGHSFFSLLIMARFIQG--AGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 151 GFYGSFQYVTLVGGQLLAIFSLFIVENIYTHEQISAFAWRYLFALGGILALLSLFLRNIM 210 G GS + +G + I I+ W YL + I + FL ++ Sbjct: 142 GLIGS---IVAMGEGVGPAIGGMIAHYIH---------WSYLLLIPMITIITVPFLMKLL 189 Query: 211 EE 212 ++ Sbjct: 190 KK 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.0 bits (80), Expect = 0.001 Identities = 31/172 (18%), Positives = 59/172 (34%), Gaps = 4/172 (2%) Query: 198 KENPIDESHKPPNEESFLAIPTPYNTTLNDSEPQEGLVQISPHPPTHYTIYPKKNRFNDL 257 N + + P E+ + T TT N+ + V + P Sbjct: 973 NVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPAT 1032 Query: 258 TNPTNPT--LEPQQETKEREPTLKKETPTTL--KPIMPISAPNTENDNKTENHKTPNHPI 313 + T T +QE+K E + T TT + + + N + + +T Sbjct: 1033 PSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 314 KKDDLQENAQEENIEEKENLKEEKRETQNAPNFSPLTPTSAKKPVMVKELSE 365 K+ E + +E++E K E +TQ P + ++ V+ +E Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144
>OMS28PORIN#OMS28 porin signature. Length = 257 Score = 30.1 bits (67), Expect = 0.014 Identities = 26/102 (25%), Positives = 49/102 (48%), Gaps = 2/102 (1%) Query: 143 NAAKNGEEHSNEGLITVNKTGQDIESLYEKMQNATSLADSLNQRS--NEITQVISLIDDI 200 N + ++ N+ L T+NK +D+ S E ++ ++ N + +SL+ D+ Sbjct: 47 NKKLDQKDQVNQALDTINKVTEDVSSKLEGVRESSLELVESNDAGVVKKFVGSMSLMSDV 106 Query: 201 AEQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAEKTQKA 242 A+ T + + A I A +G G V + +K ++TQKA Sbjct: 107 AKGTVVASQEATIVAKCSGMVAEGANKVVEMSKKAVQETQKA 148
>FLAGELLIN#Flagellin signature. Length = 507 Score = 245 bits (627), Expect = 2e-77 Identities = 126/518 (24%), Positives = 210/518 (40%), Gaps = 22/518 (4%) Query: 2 AFQVNTNINAMNAHVQSALTQNALKTSLERLSSGLRINKAADDASGMTVADSLRSQVSSL 61 A +NTN ++ +Q++L +++ERLSSGLRIN A DDA+G +A+ S + L Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAIANTNDGMGIIQVADKAMDEQLKILDTVKVKATQAAQDGQTTESRKAIQSDIVRLIQ 121 QA N NDG+ I Q + A++E L V+ + QA + K+IQ +I + ++ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 GLDNIGNTTTYNGQALLSGQFTNKEFQVGAYSNQSIKASIGSTTSDKIGQVRI-ATGALI 180 +D + N T +NG +LS + QVGA ++I + +G G Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 181 TASGDISLTFKQVDGVNDVTLESVKVSSSAGTGIGVLAEVINKNSNRTGVKAYASVITTS 240 GD+ +FK V G + + + K +G V ++ V A +TT Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 241 DVAVQSGSLSNLTLNGIHLGNIADIKKNDSDGRLVAAINAVTSETGVEAYTDQKGRLNLR 300 D N + K A A+ + + + + Sbjct: 240 DAE-----------NNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTID 288 Query: 301 SIDGRGIEIKTDSVSNGPSALTMVNGGQDLTKGSTNYGRLSLTRLDAKSINV------VS 354 + G K + NG V S + +N + Sbjct: 289 TKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKT 348 Query: 355 ASDSQHLGFTAIGFGESQVAETTVNLRDVTGNFNANVKSASGANYNAVIASGNQSL---G 411 ++S L ++ TVN + T N + + +G + S Sbjct: 349 KNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINE 408 Query: 412 SGVTTLRGAMVVIDIAESAMKMLDKVRSDLGSVQNQMISTVNNISITQVNVKAAESQIRD 471 + + +SA+ +D VRS LG++QN+ S + N+ T N+ +A S+I D Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIED 468 Query: 472 VDFAEESANFNKNNILAQSGSYAMSQANTVQQNILRLL 509 D+A E +N +K IL Q+G+ ++QAN V QN+L LL Sbjct: 469 ADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLL 506
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.020 Identities = 22/167 (13%), Positives = 61/167 (36%), Gaps = 18/167 (10%) Query: 151 AQVKLNVFNGFSDVNNVKEKSAT--YRSNVATLEYSRQSIFLQVVQQYYEYFNNLARMIA 208 ++KL F +V+ + T + +T + + L + ++ E LAR+ Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINR 225 Query: 209 LQKKLEQIQTDIKRVTKLYDKGLTTIDDL-----QSLKAQGNLSEY--DILDMQFALEQN 261 + ++ + + L K + + ++A L Y + ++ + Sbjct: 226 YENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285 Query: 262 RLTLEYLTNLNVKNLKKTTIDVPNLQLRE-RKDLVSLREQISALKYQ 307 + + +T K +D +LR+ ++ L +++ + + Sbjct: 286 KEEYQLVTQ----LFKNEILD----KLRQTTDNIGLLTLELAKNEER 324
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.4 bits (118), Expect = 4e-09 Identities = 22/69 (31%), Positives = 34/69 (49%) Query: 40 STGIVDSIKVTEGSVVKKGDVLLLLYNQDKQAQSDSTEQQLIFAKKQYQRYNKIGGAVDK 99 IV I V EG V+KGDVLL L +A + T+ L+ A+ + RY + +++ Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 100 NTLEGYEFT 108 N L + Sbjct: 163 NKLPELKLP 171 Score = 30.2 bits (68), Expect = 0.008 Identities = 21/150 (14%), Positives = 51/150 (34%), Gaps = 21/150 (14%) Query: 70 QAQSDSTEQQLIFAKKQYQRYNKIGGAVDKNTLEGYEFTYRRLESDYAYSIAVLNKTILR 129 +++ S +++ + ++ +I + + T T +++ +++R Sbjct: 279 ESEILSAKEEYQLVTQLFKN--EILDKLRQTTDNIGLLTLELAKNE-----ERQQASVIR 331 Query: 130 APFDGVIASKNIQVGEGVSANNTVLLRLVSHARKLVIE--FDSKYINAVKVG-------D 180 AP + + GV L+ +V L + +K I + VG + Sbjct: 332 APVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE 391 Query: 181 TYTYSIDGDSNQHEAKITKIYP--TVDENT 208 + Y+ G K+ I D+ Sbjct: 392 AFPYTRYGYL---VGKVKNINLDAIEDQRL 418
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 898 bits (2323), Expect = 0.0 Identities = 286/1040 (27%), Positives = 518/1040 (49%), Gaps = 42/1040 (4%) Query: 1 MYKTAINRPITTLMFALAIVFFGVMGFKKLSVALFPKIDLPTVVVTTTYPGASAEIIESK 60 M I RPI + A+ ++ G + +L VA +P I P V V+ YPGA A+ ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTDKIEEAVMGIDGIKKVTSTSSKNVSIVV-IEFELEKPNEEALNDVMNKISSVR-FDDS 118 VT IE+ + GID + ++STS S+ + + F+ + A V NK+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 119 NIKKPSINKFDTDSQPIISLFVSSSSVPAT--TLNDYAKNTIKPMLQKINGVGGVQLNGF 176 +++ I+ + S ++ S + T ++DY + +K L ++NGVG VQL G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179 Query: 177 RERQIRIYADPTLMNKYNLTYADLFSTLKAENVEIDGGRIVNS------QRELSILINAN 230 + +RI+ D L+NKY LT D+ + LK +N +I G++ + Q SI+ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 231 SYSVADVEKIQV-----GNHVRLGDIAKIEIGLEEDNTFASFKDKPGVILEIQKIAGANE 285 + + K+ + G+ VRL D+A++E+G E N A KP L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 286 IEIVDRVYEALKRIQAISP-NYEIRPFLDTTSYIRTSIEDVKFDLILGAILAVLVVFAFL 344 ++ + L +Q P ++ DTT +++ SI +V L +L LV++ FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 345 RNGTITLVSAISIPISIMGTFALIQWMGFSLNMLTMVALTLAIGIIIDDAIVVIENIHK- 403 +N TL+ I++P+ ++GTFA++ G+S+N LTM + LAIG+++DDAIVV+EN+ + Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 404 KLEMGMSKRKASYEGVREIGFALVAISAMLLSVFVPIGNMKGIIGRFFQSFGITVALAIA 463 +E + ++A+ + + +I ALV I+ +L +VF+P+ G G ++ F IT+ A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 464 LSYVVVVTIIPMVSSVVVNPRHS-------RFYVWSEPFFKALESRYTRLLQWVLNHKLI 516 LS +V + + P + + ++ P + F+ W F + YT + +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 517 IFITVVLVFVGSLFVASKLGMDFMLKEDRGRFLVWLKAKPGVSIDY----MTQKSKIFQK 572 + L+ G + + +L F+ +ED+G FL ++ G + + + Q + + K Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 573 AIEKHDEVEFTTLQVGY-GTSQNPFKAKIFVQLKPLKERKKEHELGQFELMSALRKELRS 631 + + E FT + G +QN FV LKP +ER E ++ + EL Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNA--GMAFVSLKPWEERNG-DENSAEAVIHRAKMELGK 656 Query: 632 LPEAKDLENINLSEVSLIGGGGDSSPFQTFVFSHSQEAVDKSVENLRKFLLESPELKGKV 691 + + + N+ + G ++ F + + D + + L + + + Sbjct: 657 IRDGF-VIPFNMPAIV---ELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 692 EGYHTSTSESQPQLQLKILRQNANKYGVSAQTIGSVVSSAFSGTSQASVFKEDGKEYDMI 751 + E Q +L++ ++ A GVS I +S+A G + + F + G+ + Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGG-TYVNDFIDRGRVKKLY 771 Query: 752 IRVPDDKRVSVEDIKRLQVRNKYDKLMFLDALVEITETKSPSSISRYNRQRSVTVLAQPN 811 ++ R+ ED+ +L VR+ +++ A + RYN S+ + + Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA- 830 Query: 812 RNAGVSLGEILTQVSKNTKEWLVEGANYRFTGEADNAKESNGEFLVALATAFVLIYMILA 871 G S G+ + + +N L G Y +TG + + S + +A +FV++++ LA Sbjct: 831 -APGTSSGDAMALM-ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLA 888 Query: 872 ALYESILEPFIIMVTMPLSFSGAFFALGLVHQPLSMFSMIGLILLIGMVGKNATLLIDVA 931 ALYES P +M+ +PL G A L +Q ++ M+GL+ IG+ KNA L+++ A Sbjct: 889 ALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFA 948 Query: 932 NE-ERKKGLNIQEAILFAGKTRLRPILMTTIAMVCGMLPLALASGDGAAMKSPIGIAMSG 990 + K+G + EA L A + RLRPILMT++A + G+LPLA+++G G+ ++ +GI + G Sbjct: 949 KDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMG 1008 Query: 991 GLMISMVLSLLIVPVFYRLL 1010 G++ + +L++ VPVF+ ++ Sbjct: 1009 GMVSATLLAIFFVPVFFVVI 1028
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 269 bits (690), Expect = 4e-75 Identities = 105/397 (26%), Positives = 180/397 (45%), Gaps = 14/397 (3%) Query: 2804 AGNNSIMWLNELFAAKGGNPLFAPYYLQDNPTEHIVTLMKDIASALGMLSNSNLKNNSTD 2863 +G L L + +A + I + + L +++ K + Sbjct: 904 SGAQGRDLLQTLLI-DSHDAGYARTMIDATSANEITKQLNTATTTLNNIASLEHKTSGLQ 962 Query: 2864 VLQLNTYTQQMSRLAKLSNFASFDSTDFSERLSSLKNQRFADATPNAMDVILKYSQRDKL 2923 L L+ SRL LS + F++RL +LK+QRFA +A +V+ +++ + + Sbjct: 963 TLSLSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFAS-LESAAEVLYQFAPKYEK 1021 Query: 2924 KNNLWATGVGGVSFVENGTGTLYGVNVGYDRFVRG---VIVGGYAAYGYSGFYER--ITN 2978 N+WA +GG S G +LYG + G D ++ G IVGG+ +YGYS F + N Sbjct: 1022 PTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFGSYGYSSFSNQANSLN 1081 Query: 2979 SKSDNVDVGLYARAFIKKSELTFSVNETWGANKTQISSNDTLLSMINQSYKYSTWTTNAK 3038 S ++N + G+Y+R F + E F G++++ ++ LL +NQSY Y ++ + Sbjct: 1082 SGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRDLNQSYNYLAYSAATR 1141 Query: 3039 VNYGYDFMFKNKSIILKPQIGLRYYYIGMSGLEGVMNNALYNQFKANADPSKKSVLTIDF 3098 +YGYDF F +++LKP +G+ Y ++G + + + S + + Sbjct: 1142 ASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKS----NSNQKVALKNGASSQHLFNASA 1197 Query: 3099 ALENRHYFNTNSYFYAIGGVGRDLLVNSMGDKLVRFIGNNTLSYRKGDLYNTFANITTGG 3158 +E R+Y+ SYFY GV ++ N V + R NT A + GG Sbjct: 1198 NVEARYYYGDTSYFYMNAGVLQEFA-NFGSSNAVSLNTFKVNATRNP--LNTHARVMMGG 1254 Query: 3159 EVRLFKSFYANAGVGARFGLDYKMIDIIGNIGMRLAF 3195 E++L K + N G L + N+GMR +F Sbjct: 1255 ELKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291 Score = 40.0 bits (93), Expect = 2e-04 Identities = 44/224 (19%), Positives = 78/224 (34%), Gaps = 19/224 (8%) Query: 251 SSGATTISGV-TFNNNGALTYKGGNGIGGSITFTNSNINHYKLNLNANSVTFNNSTLGSM 309 + G T+ + N N T + G G S+T ++++ K +N ++ S L Sbjct: 386 AGGKNTVVNINRINTNADGTIRVG-GFKASLTTNAAHLHIGKGGINLSNQASGRSLLVEN 444 Query: 310 PNGNANTIGNAYILNANNITFNNLTFNGGWFVFDRTNANVNFQGTTTINNPTSPFVNMTG 369 GN G L NN G + ++AN F+ T N T+ F N Sbjct: 445 LTGNITVDGP---LRVNNQV--------GGYALAGSSANFEFKAGTDTKNGTATFNNDIS 493 Query: 370 KVNINANAIFNIQNYTPSIGSAYTLFSMKNGNITYNDVNNLWNIIRLKNTKATKDNSKNT 429 + I + F+ + ++ V N NI +L A+ + + Sbjct: 494 LGRFVNLKVDAHTANFKGIDTGNGGFNT----LDFSGVTNKVNINKL--ITASTNVAVKN 547 Query: 430 TSNNNTHTYYVTYNLGGMLYHFRQIFSPNSIVLQSVYYGANNIY 473 + N ++G + I S + I + G +IY Sbjct: 548 FNINELVVKTNGVSVGEYTHFSEDIGSQSRINTVRLETGTRSIY 591 Score = 33.9 bits (77), Expect = 0.016 Identities = 15/100 (15%), Positives = 31/100 (31%), Gaps = 5/100 (5%) Query: 702 SYTFDGINNTFNEDKFNGGSFNFNHAEQTNAFNNNSFNGGSFSFNAKQVNFNHNSFNGGV 761 SY+ + E FN + ++A Q +N + G+ + N + G Sbjct: 272 SYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTHIGTLDLW-QSAGLNIIAPPEGG 330 Query: 762 FNF---NNTPKASFTNDTFNVNNQFKING-TQTDFTFSKG 797 + + + N + + N TQ + Sbjct: 331 YKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSA 370
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 30.4 bits (68), Expect = 0.001 Identities = 15/33 (45%), Positives = 20/33 (60%) Query: 16 KRKRLLTELAELEAEIKVGSERRSSFNVSLSPS 48 R +L ELAEL AE+K+ S ++ N LS S Sbjct: 149 ARSKLREELAELTAELKIYSVIQAEINKHLSSS 181
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.6 bits (134), Expect = 6e-11 Identities = 24/110 (21%), Positives = 45/110 (40%), Gaps = 6/110 (5%) Query: 182 ILIAEDSLSALKTLEKIVQTLELRYLAFPNGRELLDYLYEKEHYQQVGVVITDLEMPNIS 241 IL+A+D + L + + N L ++ +V+TD+ MP+ + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA----GDGDLVVTDVVMPDEN 61 Query: 242 GFEVLKTIKADHRTEHLPVIINSSMSSDSNRQLAQSLEADGFVVKSNILE 291 F++L IK LPV++ S+ ++ A A ++ K L Sbjct: 62 AFDLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 30.5 bits (68), Expect = 0.015 Identities = 35/161 (21%), Positives = 72/161 (44%), Gaps = 12/161 (7%) Query: 316 KKRLDKIYRLK----QRVLGTLGGINPNFKKEILECMQDDLNISKALSVLESMLSSTNEK 371 + LD++ RL+ Q L I KK+ E ++ ++ +S S + Sbjct: 208 ENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDKSQKSPEDNS 267 Query: 372 LDQNPKNKALKGEIL--ANLKFIEELLGIGFKD--PSAYFQLGVSESEKQEIESKIEE-- 425 ++ +P + A + ++ N + +L I KD SAY + + ++ E+ S IEE Sbjct: 268 IELSPSDSAWRTNLVVRTNKALYQFILRIAQKDNFASAYLTVKLEYPQRHEVSSVIEEEL 327 Query: 426 --RKRAKEQKDFLKADSIREELLNHKIALMDTPQGTIWEKL 464 R+ AK Q++ +K +++ +++ + Q EK+ Sbjct: 328 KKREEAKRQRELIKQENLNTTAYINRVMMASNEQIINKEKI 368
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 771 bits (1993), Expect = 0.0 Identities = 431/482 (89%), Positives = 452/482 (93%), Gaps = 4/482 (0%) Query: 1 MELQQTHRKMNRPLVSLVLAGALVSAIPQESHAAFFTTVIIPAIVGGIATGTAVGTVSGL 60 ME+QQTHRK+NRPLVSL L GALVS PQ+SHAAFFTTVIIPAIVGGIATG AVGTVSGL Sbjct: 1 MEIQQTHRKINRPLVSLALVGALVSITPQQSHAAFFTTVIIPAIVGGIATGAAVGTVSGL 60 Query: 61 LSWGLKQAEEANKTPDKPDKVWRIQAGRGFNNFPNKEYDLYQSLLSSKIDGGWDWGNAAR 120 L WGLKQAEEANKTPDKPDKVWRIQAG+GFN FPNKEYDLY+SLLSSKIDGGWDWGNAAR Sbjct: 61 LGWGLKQAEEANKTPDKPDKVWRIQAGKGFNEFPNKEYDLYKSLLSSKIDGGWDWGNAAR 120 Query: 121 HYWVKGGQWNKLEVDMKDAVGTYKLSGLRNFTGGDLDVNMQKATLRLGQFNGNSFTSYKD 180 HYWVK GQWNKLEVDM++AVGTY LSGL NFTGGDLDVNMQKATLRLGQFNGNSFTSYKD Sbjct: 121 HYWVKDGQWNKLEVDMQNAVGTYNLSGLINFTGGDLDVNMQKATLRLGQFNGNSFTSYKD 180 Query: 181 SADRTTRVNFNAKNISIDNFVEINNRVGSGAGRKASSTVLTLQASEGITSSKNAEISLYD 240 SADRTTRV+FNAKNI IDNF+EINNRVGSGAGRKASSTVLTLQASEGITS +NAEISLYD Sbjct: 181 SADRTTRVDFNAKNILIDNFLEINNRVGSGAGRKASSTVLTLQASEGITSRENAEISLYD 240 Query: 241 GATLNLASNSVKLNGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVDFNHLTVGDQNAAQA 300 GATLNLASNSVKL GNVWMGRLQYVGAYLAPSYSTINTSKVTGEV+FNHLTVGD NAAQA Sbjct: 241 GATLNLASNSVKLMGNVWMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQA 300 Query: 301 GIIASNKTHIGTLDLCHSAGLNIIAPPEGGYKDKPNST---TSQSGTKNDKQEISQNNNS 357 GIIASNKTHIGTLDL SAGLNIIAPPEGGYKDKPN T+Q+ KNDKQE SQ NNS Sbjct: 301 GIIASNKTHIGTLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQ-NNS 359 Query: 358 NTEVINPPNNTQKTETEPTQVIDGPFAGGKDTVVNIDRINTKADGTIRVGGFKASLTTNA 417 NT+VINPPN+ QKTE +PTQVIDGPFAGGK+TVVNI+RINT ADGTIRVGGFKASLTTNA Sbjct: 360 NTQVINPPNSAQKTEIQPTQVIDGPFAGGKNTVVNINRINTNADGTIRVGGFKASLTTNA 419 Query: 418 AHLNIGKGGVNLSNQASGRTLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEFKAGV 477 AHL+IGKGG+NLSNQASGR+LLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEFKAG Sbjct: 420 AHLHIGKGGINLSNQASGRSLLVENLTGNITVDGPLRVNNQVGGYALAGSSANFEFKAGT 479 Query: 478 DA 479 D Sbjct: 480 DT 481
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 620 bits (1599), Expect = 0.0 Identities = 359/405 (88%), Positives = 379/405 (93%) Query: 1 MFELANRSKDIDTLYTHSGAKGRDLLQTLLIDSHDAGYARQMIDNTSTGEITKQLNAATD 60 +FELANRS DIDTLY +SGA+GRDLLQTLLIDSHDAGYAR MID TS EITKQLN AT Sbjct: 887 VFELANRSNDIDTLYANSGAQGRDLLQTLLIDSHDAGYARTMIDATSANEITKQLNTATT 946 Query: 61 ALNNVASLEHKTSGLQTLSLSNAMILNSRLVNLSRKHTNHINSFAQRLQALKGQRFASLE 120 LNN+ASLEHKTSGLQTLSLSNAMILNSRLVNLSR+HTNHI+SFA+RLQALK QRFASLE Sbjct: 947 TLNNIASLEHKTSGLQTLSLSNAMILNSRLVNLSRRHTNHIDSFAKRLQALKDQRFASLE 1006 Query: 121 SAAEVLYQFAPKYEKPTNVWANAIGGASLNSGSNASLYGTSAGADAYLNGEVEAIVGGFG 180 SAAEVLYQFAPKYEKPTNVWANAIGG SLNSG NASLYGTSAG DAYLNGEVEAIVGGFG Sbjct: 1007 SAAEVLYQFAPKYEKPTNVWANAIGGTSLNSGGNASLYGTSAGVDAYLNGEVEAIVGGFG 1066 Query: 181 SYGYSSFSNQANSLNSGANNANFGVYSRFFANQHEFDFEAQGALGSDQSSLNFKSALLQD 240 SYGYSSFSNQANSLNSGANN NFGVYSR FANQHEFDFEAQGALGSDQSSLNFKSALL+D Sbjct: 1067 SYGYSSFSNQANSLNSGANNTNFGVYSRIFANQHEFDFEAQGALGSDQSSLNFKSALLRD 1126 Query: 241 LNQSYNYLAYSATARASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNSQSQVALKNG 300 LNQSYNYLAYSA RASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNS +VALKNG Sbjct: 1127 LNQSYNYLAYSAATRASYGYDFAFFRNALVLKPSVGVSYNHLGSTNFKSNSNQKVALKNG 1186 Query: 301 ASSQHLFNANANVEARYYYGDTSYFYLHAGVLQEFAHFGSNDVASLNTFKINAARSPLST 360 ASSQHLFNA+ANVEARYYYGDTSYFY++AGVLQEFA+FGS++ SLNTFK+NA R+PL+T Sbjct: 1187 ASSQHLFNASANVEARYYYGDTSYFYMNAGVLQEFANFGSSNAVSLNTFKVNATRNPLNT 1246 Query: 361 YARAMMGGELRLAKEVFLNLGVVYLHNLISNASHFASNLGMRYSF 405 +AR MMGGEL+LAKEVFLNLG VYLHNLISN HFASNLGMRYSF Sbjct: 1247 HARVMMGGELKLAKEVFLNLGFVYLHNLISNIGHFASNLGMRYSF 1291
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.7 bits (222), Expect = 2e-23 Identities = 56/233 (24%), Positives = 102/233 (43%), Gaps = 10/233 (4%) Query: 11 KVAVITGASSGIGLECALMLLDQGYKVYALSRRATLCVALNHALC------ECVDIDVSD 64 K+A ITGA+ GIG A L QG + A+ + +L E DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 65 SNALKEVFLNISAKEDHCDVLINSAGYGVFGSVEDTPIEEVKKQFSVNFFALCEVVQLCL 124 S A+ E+ I + D+L+N AG G + EE + FSVN + + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 125 PLLKNKPHSKIFNLSSIAGRVSMLFLGHYSASKHALEAYSDALRLELKPFNVQVCLIEPG 184 + ++ I + S V + Y++SK A ++ L LEL +N++ ++ PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 185 PVKSNWEKTAFENDERKDSVYALEVNAAKNFYSGVYQNAL-NAKEVAQKIVFL 236 +++ + + + ++ + V + + F +G+ L ++A ++FL Sbjct: 189 STETDMQWSLWADENGAEQVIK---GSLETFKTGIPLKKLAKPSDIADAVLFL 238
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 25.2 bits (55), Expect = 0.035 Identities = 16/69 (23%), Positives = 27/69 (39%), Gaps = 12/69 (17%) Query: 12 LKDALIDYLFEKGFDDFFYV--ECYKYAASSLLLSQKEQVSGRKDYAKFKLFLSEEVALP 69 L+ A + + F Y + +SSL+ K+ A+F + V Sbjct: 98 LQMANTNKTLASDLETVFLTTSTEYSFLSSSLV----------KEVARFGGNVEHFVPSH 147 Query: 70 LAQALKNQF 78 +A AL +QF Sbjct: 148 VAAALYDQF 156
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 752 bits (1942), Expect = 0.0 Identities = 225/1044 (21%), Positives = 460/1044 (44%), Gaps = 42/1044 (4%) Query: 6 IIEFSLRQRVIVIVGAILILFFGTYSFIHTPVDAFPDISPTQVKIILKLPGSSPEEMENN 65 + F +R+ + V AI+++ G + + PV +P I+P V + PG+ + +++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 66 IVRPLELELLGLKGQKSLRSVSKYSIS-DITIDFDDSVDIYLARNIVNERLSSVMKDLPM 124 + + +E + G+ + S S + S IT+ F D +A+ V +L LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 125 GVEGGMAPIVTPLSDIFMF----TIDGNITEIEKRQLLDFVIRPQLRMISGVADVNSIGG 180 V+ + S M + + T+ + + ++ L ++GV DV G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 FSKAFVIVPDFNDMARLGVSISDLESAVRVNLRNSGAGRVDR----DGETFLVKI--QTA 234 A I D + + + ++ D+ + ++V AG++ G+ I QT Sbjct: 181 -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 235 SLSLEDIGKITV--STNLGHLHIKDFAKVISQSRTRLGFVTKDGVGETTEGLVLSLKEAN 292 + E+ GK+T+ +++ + +KD A+V +G + AN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGAN 298 Query: 293 TKKIITQVYQKLEELKPLLPSGVSLNVFYDRSEFTQKAIATVSKTLIEAVVLIIITLFLF 352 + KL EL+P P G+ + YD + F Q +I V KTL EA++L+ + ++LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 353 LGNLRASVAVGVILPLSLSVAFIFIKLNNLTLNLMSLGGLIIAIGMLIDSAVVVVENAFE 412 L N+RA++ + +P+ L F + ++N +++ G+++AIG+L+D A+VVVEN E Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV-E 417 Query: 413 KLSANTKTTKLHAIYRSCKEIAVSVVSGVVIIIVFFVPILTLQGLEGKMFRPLAQSIVYA 472 ++ K A +S +I ++V +++ F+P+ G G ++R + +IV A Sbjct: 418 RVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSA 477 Query: 473 LLGTLVLSITIIPVVSSLVLK--ATPHSET---FLTRFLNRIYGPLLEFFVRNPKKVI-- 525 + ++++++ + P + + +LK + H E F F N + + + + K++ Sbjct: 478 MALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWF-NTTFDHSVNHYTNSVGKILGS 536 Query: 526 ----LGAFVFLIA-SLSLFPFVGKNFMPTLDEGDVVLSVETTPSISLDQSKDLILNIESA 580 L + ++A + LF + +F+P D+G + ++ + ++++ ++ + Sbjct: 537 TGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596 Query: 581 IKKHVKEVKTIVARTGSDELGLDLGGLNQTDTFISFIPKKEWSVKTKDELL-EKIMDSLK 639 K+ K V G G Q + ++F+ K W + DE E ++ K Sbjct: 597 YLKNEKANVESVFTVN----GFSFSGQAQ-NAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 640 -DFKGINFSFTQPIEM-RISEMLTGVRGDLA-VKIFGDDISELNGLSFQIA-QALKGIKG 695 + I F P M I E+ T D + G L Q+ A + Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 696 SSEVLTTLNEGVNYLYVTPNKEAMANVGITSDEFSKFLKSALEGLIVDVIPTGISRTPVM 755 V E + ++E +G++ + ++ + +AL G V+ + Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 756 IRQEIDFASSITKIKSLALTSKYGVLVPITSIAKIEEVDGPVSIVREDSRRMSVVRSNVV 815 ++ + F + L + S G +VP ++ V G + R + ++ Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 816 GRDLNSFVEEAKKVIAQNVKLPPSYYITYGGQFENQQRANKRLSTVIPLSILAIFFILFF 875 + + +A KLP + G ++ + + ++ +S + +F L Sbjct: 832 PGTSSGDAMALMENLA--SKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 876 TFKSIPLALLILLNIPFAVTGGLIALFAVGEYISVPASVGFIALFGIAVLNGVVMIGYFK 935 ++S + + ++L +P + G L+A + V VG + G++ N ++++ + K Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 936 ELLL-QGKSVEECVLLGAKRRLRPVLMTACIAGLGLIPLLFSHSVGSEVQKPLAIVVLGG 994 +L+ +GK V E L+ + RLRP+LMT+ LG++PL S+ GS Q + I V+GG Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 995 LVTSSALTLLLLPPMFMLIAKKIK 1018 +V+++ L + +P F++I + K Sbjct: 1010 MVSATLLAIFFVPVFFVVIRRCFK 1033
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.026 Identities = 25/159 (15%), Positives = 59/159 (37%), Gaps = 31/159 (19%) Query: 7 WLMLMGVFLMGVFLGAKEYPEIVLEEKNLQPMGLKVIKLDKEIFSKGLPFNAYIDFDSKS 66 L+ F+MG + A +L + +++ N + +S Sbjct: 56 RPRLVAYFIMGFLVIA-----FIL---------SVLGQVEI-----VATANGKLTHSGRS 96 Query: 67 SVVQSLSFDASVVAVYKREGEQVKAGDAICEVSSID-------LSNLYFELQNNQNKLKI 119 ++ + ++ V + +EGE V+ GD + +++++ + + + Q + +I Sbjct: 97 KEIKPIE-NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 120 AKDITKKDLELYKAGVIPKREYQTSFLASEEMGLKVNQL 158 +EL K + + SEE L++ L Sbjct: 156 LSRS----IELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 25.1 bits (55), Expect = 0.042 Identities = 10/36 (27%), Positives = 16/36 (44%), Gaps = 10/36 (27%) Query: 5 DTLLQR---LEKLSM--LEIKDEHKES-----VKGH 30 D + +++L M EIK E+KE +K Sbjct: 202 DYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSK 237
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 32.3 bits (73), Expect = 8e-04 Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 47 TNEKSHEINLEENSPNNPNTPNDEKAPHNEEDHNN 81 N+ ++PNNP+ PN+ P+N ++ NN Sbjct: 284 ANDDQPNNPDNPDNPNNPDNPNNPDEPNNPDNPNN 318 Score = 31.1 bits (70), Expect = 0.002 Identities = 10/34 (29%), Positives = 20/34 (58%) Query: 48 NEKSHEINLEENSPNNPNTPNDEKAPHNEEDHNN 81 + + + N+P+NP+ PN+ P+N ++ NN Sbjct: 279 EDIHFANDDQPNNPDNPDNPNNPDNPNNPDEPNN 312 Score = 27.3 bits (60), Expect = 0.034 Identities = 14/49 (28%), Positives = 23/49 (46%), Gaps = 1/49 (2%) Query: 40 TNESPSQTNEKSHEINLEENSPNNPNTPNDEKAPHNEEDHNNTLFQNLD 88 N+ + N +N PNNP+ PN+ P+N ++ +N N D Sbjct: 284 ANDDQPNNPDNPDNPNNPDN-PNNPDEPNNPDNPNNPDNPDNGDNNNSD 331 Score = 26.9 bits (59), Expect = 0.048 Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 5/61 (8%) Query: 29 EMPTTSHAISQTNESPSQTNEKSHEINLEENSPNNPNTPNDEKAPHNEEDHNNTLFQNLD 88 ++ + ++P N + N+P+ PN P++ P N ++ +N N D Sbjct: 280 DIHFANDDQPNNPDNPDNPNNPDNP-----NNPDEPNNPDNPNNPDNPDNGDNNNSDNPD 334 Query: 89 A 89 A Sbjct: 335 A 335
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.2 bits (146), Expect = 2e-12 Identities = 29/129 (22%), Positives = 50/129 (38%), Gaps = 13/129 (10%) Query: 182 GEVLFLDDSKTARKTLKNHLSKLGFSITEAVDGEDGLNKLEMLFKKYGDDLRKHLKFIIS 241 +L DD R L LS+ G+ + + + +++ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA----------AGDGDLVVT 53 Query: 242 DVEMPKMDGYHFLFKLQKDPRFAYIPVIFNSSICDNYSAERAKEMGAVAYLVK-FDAEKF 300 DV MP + + L +++K +PV+ S+ +A +A E GA YL K FD + Sbjct: 54 DVVMPDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111 Query: 301 TEEISKILD 309 I + L Sbjct: 112 IGIIGRALA 120
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 2e-05 Identities = 29/168 (17%), Positives = 60/168 (35%), Gaps = 2/168 (1%) Query: 103 TIRDTGSDTNNGRENEIEEVVKKLQAITSQNLEGAKETSGTKEAPEKEVKKENKEKAKEE 162 T+ T T N + ++ V + I + + + E EN ++ + Sbjct: 991 TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT 1050 Query: 163 VKTNKTPTTENLTSDNPLADEPDLDY-ANMSAEEVEAEIERLLNKRQEADKERRAQKKQE 221 V+ N+ TE + +A E + AN EV + KE +K+E Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110 Query: 222 DQAKPKQEVAPAKETPKTETPKAPKTETKAKAKADTEENKAPSIGVEQ 269 ++ + +PK ++ET A+ P++ +++ Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ-AEPARENDPTVNIKE 1157
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.3 bits (141), Expect = 3e-12 Identities = 24/121 (19%), Positives = 55/121 (45%), Gaps = 4/121 (3%) Query: 86 VLAIDDSSTDRAIIRKCLKPLGITLLEATNGLEGLEMLKNGDKIPDAILVDIEMPKMDGY 145 +L DD + R ++ + L G + +N + GD D ++ D+ MP + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMPDENAF 63 Query: 146 TFASEVRKYNKFKNLPLIAVTSRVTKTDRMRGVESGMTEYITKPYSGEYLTTVVKRSIKL 205 ++K +LP++ ++++ T ++ E G +Y+ KP+ L ++ R++ Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 206 E 206 Sbjct: 122 P 122
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 422 bits (1086), Expect = e-145 Identities = 159/576 (27%), Positives = 276/576 (47%), Gaps = 71/576 (12%) Query: 10 RLILAIALSFLFIALYSYFFQKPNKP--TTETTKQETTNNHTTISPNAPNAQHFSVTQTI 67 R +L IAL F+ ++ + Q N +TT+ TT + P + Sbjct: 5 RNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASG-------- 56 Query: 68 PQESLLSTISFEHARIEIDSLGR--IKQVYLKDKKYLTPKEKGFLEHVGHLFSSKENSQP 125 + L ++ + + I++ G + + K L + L F + S Sbjct: 57 --QGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGL 114 Query: 126 SLKELPLLAADKLKPLEVRFLDPTLNNKAFNTPYSASKTTLGPNEQLV--LTQDLGVLSI 183 + ++ P A+ +PL +N A G NE V D + Sbjct: 115 TGRDGPDNPANGPRPL-------------YNVEKDAYVLAEGQNELQVPMTYTDAAGNTF 161 Query: 184 IKTLTFYDDLHYDLKIAFKSSNN------------------LIPSYVITNGYRPVADLDS 225 KT Y + + + N L P + + Sbjct: 162 TKTFVLKRG-DYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFAL----- 215 Query: 226 YTFSGVLLENNDKKIEKIE---DKDAKEIKRFSNTLFLSSVDRYFTTLLFTKDPQGFEAL 282 +TF G D+K EK + D + + S +++ + +YF T + G Sbjct: 216 HTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHN-DGTNNF 274 Query: 283 IDSEIGTKNPLGFISLKNEA-----------NLHGYIGPKDYRSLKAISPMLTDVIEYGL 331 + +G N + I K++ N ++GP+ + A++P L ++YG Sbjct: 275 YTANLG--NGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGW 332 Query: 332 ITFFAKGVFVLLDYLYQFVGNWGWAIIFLTIIVRIVLYPLSYKGMVSMQKLKELAPKMKE 391 + F ++ +F LL +++ FVGNWG++II +T IVR ++YPL+ SM K++ L PK++ Sbjct: 333 LWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA 392 Query: 392 LQEKYKGEPQKLQAHMMQLYKKHGANPLGGCLPLILQIPVFFAIYRVLYNAVELKSSEWV 451 ++E+ + Q++ MM LYK NPLGGC PL++Q+P+F A+Y +L +VEL+ + + Sbjct: 393 MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFA 452 Query: 452 LWIHDLSIMDPYFILPLLMGASMYWHQSVTPNTMTDPMQAKIFKLLPLLFTIFLITFPAG 511 LWIHDLS DPY+ILP+LMG +M++ Q ++P T+TDPMQ KI +P++FT+F + FP+G Sbjct: 453 LWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSG 512 Query: 512 LVLYWTTNNILSVLQQLIINKVLENKKRVHAQNIKE 547 LVLY+ +N+++++QQ +I + LE K+ +H++ K+ Sbjct: 513 LVLYYIVSNLVTIIQQQLIYRGLE-KRGLHSREKKK 547
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 34.1 bits (78), Expect = 0.001 Identities = 33/134 (24%), Positives = 53/134 (39%), Gaps = 25/134 (18%) Query: 216 LSIVGKPNAGKSSLLNAMLLEERA---LVSDIKGTTR-DTIEE-------------VIEL 258 + ++ +AGK++L ++L A L S KGTTR D + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 259 KGHKVRLIDTAGIRESADEIERLGIEKSLKSLENCDIILGVFDLSKPLEKEDFNLIDTLN 318 + KV +IDT G + E+ R SL L D + + ++ + L L Sbjct: 66 ENTKVNIIDTPGHMDFLAEVYR-----SLSVL---DGAILLISAKDGVQAQTRILFHALR 117 Query: 319 RAKKPCIVVLNKND 332 + P I +NK D Sbjct: 118 KMGIPTIFFINKID 131
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 28.9 bits (64), Expect = 0.027 Identities = 22/97 (22%), Positives = 36/97 (37%), Gaps = 6/97 (6%) Query: 155 SKSMGDLLAKAAPIERILKAYSVPVSPLENYEKIYYQNAFKPKVRITFDNNSDTEIKNAL 214 + + D L P + +A + E + YQ + FD + IKN L Sbjct: 536 AVNPSDPLETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQL 595 Query: 215 MSAYAR-VLTPSDEEKLYQ-----IKNEVFTENTNGI 245 A + T D+ KL I+++ F + N I Sbjct: 596 AELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNI 632
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 293 bits (752), Expect = e-105 Identities = 174/175 (99%), Positives = 175/175 (100%) Query: 1 MKNQVKKILGMSVIAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK 60 MKNQVKKILGMSV+AAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK Sbjct: 1 MKNQVKKILGMSVVAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEK 60 Query: 61 YSGVFLGRAEDLITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRS 120 YSGVFLGRAEDLITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRS Sbjct: 61 YSGVFLGRAEDLITNNDVDYSTNQATAKARANLAANLKSTLQKDLENEKTRTVDASGKRS 120 Query: 121 ISGTDTEKISQLVDKELIASKMLARYVGKDRVFVLVGLDKQIVDKVREELGMVKK 175 ISGTDTEKISQLVDKELIASKMLARYVGKDRVFVLVGLDKQIVDKVREELGMVKK Sbjct: 121 ISGTDTEKISQLVDKELIASKMLARYVGKDRVFVLVGLDKQIVDKVREELGMVKK 175