>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 58.3 bits (141), Expect = 9e-16 Identities = 18/46 (39%), Positives = 28/46 (60%) Query: 23 HKVMIVALIVXCITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 68 ++ +++ C+T ++ +TRK LCE+ R G EVA F AYES Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 656 bits (1695), Expect = 0.0 Identities = 243/833 (29%), Positives = 397/833 (47%), Gaps = 38/833 (4%) Query: 7 WVAAIIFLYSFPGYAEETFDTHFMIGGMKGEKVSEYHFDNKQP-LPGNYELDFYVNNQWR 65 +VA + AE F+ F+ F+N Q PG Y +D Y+NN + Sbjct: 31 FVACAFAAQAPLSSAELYFNPRFLADD-PQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 66 GKQDITI----PESPVKPCLPKVLLTKLGVKTGNLNT-----EDNCILLDKAVHGGQYQW 116 +D+T E + PCL + L +G+ T +++ +D C+ L +H Q Sbjct: 90 ATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQL 149 Query: 117 DISEHRLNLTVPQAYINELERGYVPPESWDRGIDAFYTSYNLSQYRSYDSNNNSNTASYG 176 D+ + RLNLT+PQA+++ RGY+PPE WD GI+A +YN S + ++ +Y Sbjct: 150 DVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYL 209 Query: 177 RFNSGLNLFSWQLHSDASYSKPD-----DMKGTWQSNTLYLEHGWSQILSTVQIGENYTS 231 SGLN+ +W+L + ++S K WQ +LE + S + +G+ YT Sbjct: 210 NLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQ 269 Query: 232 SLIFDSLRFSGIRLFRDMQMLPDSMQSFTPLVQGVAQSNALITVSQNGYIIYQKEVPPGP 291 IFD + F G +L D MLPDS + F P++ G+A+ A +T+ QNGY IY VPPGP Sbjct: 270 GDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGP 329 Query: 292 FTIADLQLSGSGSDLDVSIKEADGSVRSFLVPYSSVPNMLQPGISNFDFIAGRSKIYGVK 351 FTI D+ +G+ DL V+IKEADGS + F VPYSSVP + + G + + AG + + Sbjct: 330 FTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQ 389 Query: 352 NQED-FLEANYIYGLNNLLTLYGGTILSDNYNAITLGNGWNT-PLGAISFDATRSSSKLN 409 ++ F ++ ++GL T+YGGT L+D Y A G G N LGA+S D T+++S L Sbjct: 390 QEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLP 449 Query: 410 NDITHEGTSYQVAYNKYLVQTATRFSVAAWRYASQDYRTFSDHLYENDKINHQSDYDDFY 469 +D H+G S + YNK L ++ T + +RY++ Y F+D Y + D Sbjct: 450 DDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVI 509 Query: 470 DIG------------RKNSLSANIMQPLSNNLGNVSLSALWRNYWGRSGNAKDYQFSYSN 517 + ++ L + Q L + LS + YWG S + +Q + Sbjct: 510 QVKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYWGTSNVDEQFQAGLNT 568 Query: 518 SWQRISYTFSASQSYDENDKEEER-FNLFISIPF--YWGDDIAKTRHQINLSNSTSFSKD 574 +++ I++T S S + + K ++ L ++IPF + D + S S S + Sbjct: 569 AFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLN 628 Query: 575 GYSSNNTGITGIAGEHDQLNYGI---YVNQQQQNNDTSLGTNLSWRTPIATIDGSYSHSK 631 G +N G+ G E + L+Y + Y N+ ++ L++R + YSHS Sbjct: 629 GRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSD 688 Query: 632 NAWQSGGSISSGLVVWPGGINITNQLSDTFAILDAPGLEGAHINGQKYNRTNSKGQVVYD 691 + Q +S G++ G+ + L+DT ++ APG + A + Q RT+ +G V Sbjct: 689 DIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLP 748 Query: 692 LMIPHRENHLVLDTANSESETELQGNRQIIAPYRGAVSYVQFTTDQRKPWYIQALRPDGS 751 +REN + LDT +L + P RGA+ +F + L + Sbjct: 749 YATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMT-LTHNNK 807 Query: 752 PLTFGYDVLDLQENNIGVVGQGSRLFIRVDEIPTGIKVALNDEQNLFCTITFQ 804 PL FG V + G+V ++++ + ++V +E+N C +Q Sbjct: 808 PLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQ 860
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 30.7 bits (69), Expect = 0.002 Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 8 NSAVLVHFTLKLDDGTTAESTRNNGKPALFRL 39 + V V +T L DGT +ST GKPA F++ Sbjct: 144 SDTVTVEYTGTLIDGTVFDSTEKAGKPATFQV 175
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.022 Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 21/118 (17%) Query: 82 YGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQ-IINA 140 Y R PE +E + R YW + N P ++ +F+ + +F G ++ Sbjct: 158 YSRFPEVKELMESQMERLARPYWEKLRNRPDMY----YFKNYNFKRCYFGLNGGDCLVAK 213 Query: 141 G-----------QGEGRYSELLAINLLEQLLLRRMEA-----INESLHPPMDNRVREA 182 G QG +Y E + LE++L +++A I + +P +V A Sbjct: 214 GDDGRTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVA 271
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.005 Identities = 17/80 (21%), Positives = 29/80 (36%), Gaps = 5/80 (6%) Query: 4 RRQPLIPGWLIPGVSAATLVVAVALAAFLALWWNAPQGDWSAVWQDS-YLWHVVRFSFWQ 62 R GWL + L V A +W+ A +++W+ ++ Sbjct: 60 RSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVAN----TSIWRLLAFINTKPVAFTLP 115 Query: 63 AFLSALLSVVPAIFLARALY 82 LS + +VV F+ LY Sbjct: 116 LALSIIFNVVVVTFMWSLLY 135
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 740 bits (1912), Expect = 0.0 Identities = 262/889 (29%), Positives = 425/889 (47%), Gaps = 45/889 (5%) Query: 1 MYQFTHQKSRIPKKTLLA-----ACCALFYSSNGAAADTVEYDSSFLMGTGASTIDVKRY 55 +YQ Q I K L F + ++ + ++ FL + D+ R+ Sbjct: 8 LYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRF 67 Query: 56 AQGNPTPPGLYNVRVFVNGQATSSLEIPFV-DIGENSAAACLTHKNLAQLHIKQPEQPVT 114 G PPG Y V +++N ++ ++ F E CLT LA + + Sbjct: 68 ENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGM 127 Query: 115 LLAREGEEEDCLDLAKSYEKADVCFDGSDQFLDLTIPQAYVLKSYGGYVDPSLWESGINA 174 L ++ C+ L A D Q L+LTIPQA++ GY+ P LW+ GINA Sbjct: 128 NLL---ADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINA 184 Query: 175 ATLAYTLNAYHTSSDND-NSDSVYGAFNSGINLGAWHFRARGNYNWTTDNGS-----DFD 228 L Y + + NS Y SG+N+GAW R +++ + + S + Sbjct: 185 GLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQ 244 Query: 229 FQDRYLQRDIPAIRSQIIMGDAYTTGETFDSVNVRGVRLYSDSRMLPSALASYAPTIRGV 288 + +L+RDI +RS++ +GD YT G+ FD +N RG +L SD MLP + +AP I G+ Sbjct: 245 HINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGI 304 Query: 289 ANSNAKVTVTQSGYKIYETTVPPGEFVIDDISPSGFGSELVVTIEEADGSKRTFTHPFSS 348 A A+VT+ Q+GY IY +TVPPG F I+DI +G +L VTI+EADGS + FT P+SS Sbjct: 305 ARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSS 364 Query: 349 VVQMQRPGVGRWDFSAGKV-IDDSLRSEPNMGQASYYYGLNNLFTGYTGIQFTDNNYLAG 407 V +QR G R+ +AG+ ++ + +P Q++ +GL +T Y G Q D Y A Sbjct: 365 VPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAF 423 Query: 408 LLGVGINT-SIGAFAVDVTHSRAEIPDDKTYQGQSYRVTWNKLFQDTGTSFNLAAYRYST 466 G+G N ++GA +VD+T + + +PDD + GQS R +NK ++GT+ L YRYST Sbjct: 424 NFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYST 483 Query: 467 QDYLGLHDALVLIDDAKHL--------SADEDKNTMQTYSRMKNQFTVSINQPLNIAYED 518 Y D + ++ + + + + +++ Q L Sbjct: 484 SGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLG----R 539 Query: 519 YGSLFISGSWTYYWAANNSRTEYNVGYSKSVSWGSFSVNLQRSWNE-DGEKDDAMYVSVS 577 +L++SGS YW +N ++ G + + +++++ + N +D + ++V+ Sbjct: 540 TSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVN 599 Query: 578 VPIENILGGKRKSS-GFRNLNTQLNTDFDGSHQLNVNSSGNT-ENNLVNYSVNAGYSLDK 635 +P + L KS + + ++ D +G G E+N ++YSV GY+ Sbjct: 600 IPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGG 659 Query: 636 NAGDLASVGGYLNYESGLGGISASASATSDNSQQYSISTDGGFVLHSGGLTFTNNSFSSN 695 + ++ LNY G G + S SD+ +Q GG + H+ G+T N Sbjct: 660 DGNSGSTGYATLNYRGGYGNANIGYSH-SDDIKQLYYGVSGGVLAHANGVTLGQP---LN 715 Query: 696 DTLVLINALGAKGARINNSNN-EIDRWGYAVTSSVSPYRENRVGLNIETLENDVELKSTS 754 DT+VL+ A GAK A++ N D GYAV + YRENRV L+ TL ++V+L + Sbjct: 716 DTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAV 775 Query: 755 ATTVPRSGSVVLTRFETDEGRSAVLNITAANGKSIPFAAEVYQGE-VMIGSMGQGGQAFV 813 A VP G++V F+ G ++ +T N K +PF A V G + GQ ++ Sbjct: 776 ANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYL 834 Query: 814 RGINDSGELIVRWYENNQTIDCKLHYQFPAQPQTQGSTNTLLLNNLTCQ 862 G+ +G++ V+W E C +YQ P + Q Q L + C+ Sbjct: 835 SGMPLAGKVQVKWGEEENAH-CVANYQLPPESQQQL----LTQLSAECR 878
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 511 bits (1316), Expect = 0.0 Identities = 294/296 (99%), Positives = 295/296 (99%) Query: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DTINYRLWVSEPPLPESVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 DTINYRLWVSEPPLP+SVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMNPRFVKRGARPLLLT 180 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSM PRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 34.3 bits (78), Expect = 4e-04 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236 + ++ EL A N T+ +K ++N+ +R D + I V +E+++++ Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643
>OUTRSURFACE#Outer surface protein signature. Length = 273 Score = 38.7 bits (90), Expect = 1e-04 Identities = 42/199 (21%), Positives = 75/199 (37%), Gaps = 38/199 (19%) Query: 395 RVTITDSLNRR--EVLYTEGEGGLKRVVKKEHADGSITRSEYDEAGRL--KAQTDAAGRR 450 ++TI D L++ E+ +G+ + R V + D + T ++E G L K T G + Sbjct: 87 KLTIADDLSKTTFELFKEDGKTLVSRKVSSK--DKTSTDEMFNEKGELSAKTMTRENGTK 144 Query: 451 TEYSLHMASGAVTAVTGPDGRTVRYGYNSQRQVTSVTYPDGLRSSREYDEKGRLAAETSR 510 EY+ + G A T+ + + ++ +G + L+ E ++ Sbjct: 145 LEYTEMKSDGTGKAKEVLKNFTLEGKVANDK--VTLEVKEGTVT---------LSKEIAK 193 Query: 511 SGETTRYSYDDPASELPTGIQDATGSTKQMA-WSRYGQLLTFTDCSGYTTRYEYDRYGQQ 569 SGE T D + T +TK+ W LT + S TT+ Sbjct: 194 SGEVTVALND----------TNTTQATKKTGAWDSKTSTLTISVNSKKTTQL-------- 235 Query: 570 IAVHREEGISTYSSYNPRG 588 V ++ T Y+ G Sbjct: 236 --VFTKQDTITVQKYDSAG 252 Score = 33.0 bits (75), Expect = 0.007 Identities = 30/139 (21%), Positives = 52/139 (37%), Gaps = 39/139 (28%) Query: 549 LTFTDCSGYTTRYEYDRYGQQIA---VHREEGISTYSSYNPRGQLVSQKDAQGRETRYEY 605 LT D TT + G+ + V ++ ST +N +G+L ++ + T+ EY Sbjct: 88 LTIADDLSKTTFELFKEDGKTLVSRKVSSKDKTSTDEMFNEKGELSAKTMTRENGTKLEY 147 Query: 606 SAAGDLTAIVAPDGSRSEIQYDAWGKAVST-------------------TQGGLTRSMGY 646 +E++ D GKA +G +T S Sbjct: 148 ----------------TEMKSDGTGKAKEVLKNFTLEGKVANDKVTLEVKEGTVTLSKEI 191 Query: 647 DAAGRITV-LTNENGSQST 664 +G +TV L + N +Q+T Sbjct: 192 AKSGEVTVALNDTNTTQAT 210
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 26.1 bits (57), Expect = 0.008 Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 20 AVYKDHPLQGSWKGYRDAHVEPD 42 +VYK + + G+ A V Sbjct: 153 SVYKAFSDRVTLPGFNSAKVTSL 175
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 39.1 bits (91), Expect = 9e-06 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 22/118 (18%) Query: 121 FERGSAQIMPFFKTLLVELAPVFDSL---DNKIIITGHTDAM---AYKNNIYNNWNLSGD 174 F A + P + L +L +L D +++ G+TD + AY N LS Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAY------NQGLSER 276 Query: 175 RALSARRVLEEAGMPEDKVMQVS-----AMADQMLLDAKNPQS-----AGNRRIEIMV 222 RA S L G+P DK+ + + K + A +RR+EI V Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.4 bits (203), Expect = 6e-21 Identities = 56/190 (29%), Positives = 88/190 (46%), Gaps = 2/190 (1%) Query: 3 KVILITGASSGIGEGIARELGMTGAKVLLGARRVERIEAIATEICRAGGIAKARELDVTD 62 K+ ITGA+ GIGE +AR L GA + E++E + + + A+A DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 RQSMADFVQAALDSWGRVDVLINNAGVMPLSPLAAGKQDEWALTIDVNIKGVLWGIGAVL 122 ++ + G +D+L+N AGV+ + + +EW T VN GV +V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 123 PVMEAQGSGQIINLGSIGALSVVPTGAVYCASKFAVR--AISDGLRQESSKIRVTCVNPG 180 M + SG I+ +GS A + A Y +SK A GL IR V+PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 181 VVESELASTI 190 E+++ ++ Sbjct: 189 STETDMQWSL 198
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 36/194 (18%), Positives = 73/194 (37%), Gaps = 8/194 (4%) Query: 2 STLSQTPSPHHQHAYWGGIFAMTLCVFVLIASEFMPVSLLTPIARDLGVTEGLAGRGIAI 61 ++ SQ+ H+Q W I L F ++ + VSL IA D Sbjct: 3 TSYSQSNLRHNQILIWLCI----LSFFSVLNEMVLNVSLPD-IANDFNKPPASTNWVNTA 57 Query: 62 SGALAVLTSLTLSTLAGKMNRKFLLLGMTVLMAVSGLIIALATSYLMYMV-GRAMIGVAI 120 + + L+ ++ K LLL ++ +I + S+ ++ R + G Sbjct: 58 FMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGA 117 Query: 121 GGFWSMSAATAIRLVPQHQVTRALAIFNAGNALATVVAAPLGSYLGATVGWRGAFLCLVP 180 F ++ R +P+ +A + + A+ V +G + + W ++L L+P Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIP 175 Query: 181 MAVVAFIWQCISLP 194 M + + + L Sbjct: 176 MITIITVPFLMKLL 189
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 62.9 bits (153), Expect = 4e-12 Identities = 30/247 (12%), Positives = 72/247 (29%), Gaps = 23/247 (9%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSN 546 L + + T +S + Y + +Q + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFNTGLED---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G +D + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLD 718 + + + Sbjct: 762 TNTLADN 768
>INTIMIN#Intimin signature. Length = 939 Score = 549 bits (1415), Expect = e-178 Identities = 226/818 (27%), Positives = 357/818 (43%), Gaps = 49/818 (5%) Query: 41 PVMAARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDS-----DATRNF 95 P++AA +L+ + VT N + ++AA L SQ S D ++ Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190 Query: 96 ITGMATAKANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155 G+A +A+ ++Q WL YGTA V L +F SSL+ L P YD+ + F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 156 HRTDDRTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215 D R +N+G G R F M G N FID D S +TR+G+G EYWRDY K S NGY Sbjct: 249 RYIDSRFTANLGAGQRFFLPE-NMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307 Query: 216 IRASGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275 R SGW +S + +DY ERPANG+DIR GYLP++P LGA LMYEQYYGD V LF DK Q Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367 Query: 276 KDPHAISAEVTYTPVPLLTLSAGHKQGKSGENDTRFGLEVNYRIGEPLAKQLDTDSIRER 335 +P A + V YTP+PL+T+ ++ G END + ++ Y+ +P ++Q++ + E Sbjct: 368 SNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNEL 427 Query: 336 RVLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLKNVQ 395 R L+GSRYDLV+RNNNI+LEY+K +++ + +P I G T + L+V K+ +GL + Sbjct: 428 RTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIV-KSKYGLDRIV 486 Query: 396 WEAPSLLAEGGKITGQGSQ----WQVTLPAYRPGKDNYYAISAVAYDNKGNTSKRVQTEV 451 W+ +L ++GG+I GSQ +Q LPAY G N Y ++A AYD GN+S V + Sbjct: 487 WDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTI 546 Query: 452 VITGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKDQIKTELTFK 511 + G D+ +T + A+G E +++ Q ++F Sbjct: 547 TVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNG-------VAQANVPVSFN 599 Query: 512 PAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMSKTVTA 571 S + + G + G+ ++ M+ + A Sbjct: 600 IVSGTAVLSANSANTNGS-----------GKATVTLKSDK-PGQVVVSAKTAEMTSALNA 647 Query: 572 ELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLRFVPQDTN 631 + S VA+GQ A T T+ V PV+ + T Sbjct: 648 NAVIFVDQTKASITEIKADKTTAVANGQDAITYTVK-VMKGDKPVSNQEVTF-----TTT 701 Query: 632 GVTVGAIS--EIKPGVYSAAVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP-LDAAHS 688 + + G ++ST G +V A + ++F +D + Sbjct: 702 LGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNI 761 Query: 689 SITLNPDKPVVGGTVTAIWTVKDAYDNPVTSLTPE---APSLAGAAAEGSTASGWTNNGD 745 I V G + +W + + + + A+ +++ T Sbjct: 762 EIVGTG----VKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEK 817 Query: 746 GTWTAQITLGSTAGELEVMPKLNGQNAAANAAKVTVVADALSSNQSKVSVAEDHVKAGES 805 GT T + + N N +K DA+++ ++ E+ Sbjct: 818 GTTTISVISSDNQTATYTIATPNSL-IVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELEN 876 Query: 806 TTVTLVAKDAHGNAISGLALSASLTGTASEGATVSSWT 843 A + + S + + + TA + + + T Sbjct: 877 VFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVAST 914 Score = 74.0 bits (181), Expect = 4e-15 Identities = 76/421 (18%), Positives = 140/421 (33%), Gaps = 45/421 (10%) Query: 976 NGQNAVAQPLVLNVAGDAS-KAEIRDMTVKVNNQLANGQSANQITLTVVDTYGNPLQGQE 1034 N N V + + G + + D T + A+G A T TV G Sbjct: 537 NSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKN-GVAQANVP 595 Query: 1035 VTLTLPQGVTSKTGNTVTTNAAGKADIELMSTVAGEHNISASVNGAQKTV---TVKFNAD 1091 V+ + G + N+ TN +GKA + L S G+ +SA + V F Sbjct: 596 VSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQ 655 Query: 1092 ASTGQANLQVDAAAQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNLPRGVKPLTGDNVW 1151 ++ D VANG+DA T T V K PV VTF G + + Sbjct: 656 TKASITEIKADKTTA-VANGQDAITYTVKV-MKGDKPVSNQEVTFTTTLGKLSNSTE--- 710 Query: 1152 VKANDEGKAELQVVSVTAGTYEITASAGNSQPSNTQTITFVADKATATVSGIEVIGNYAL 1211 K + G A++ + S T G ++A + T IE++G Sbjct: 711 -KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGT--- 766 Query: 1212 ADGNAKQTYKVTVTDANNNLLK---DSEVTLTASPANLVLTPNGTAKTNEQGQAIFTATT 1268 G + V + NL + + T ++ + + + + + T + Sbjct: 767 --GVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISV 824 Query: 1269 TVAAKYTLTAKVSQADGQESTKTAESKFVADDTNAVLTASSDVTSLVADGISTAKLEVTL 1328 + T T + N+++ + D ++T K Sbjct: 825 ISSDNQTAT------------------YTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGK 866 Query: 1329 MSANNPVGGNMWVDIKTPEGVTEKDYQFLPSKNDHFVSGKITRTFSTSKPGVYTFTFNAL 1388 + ++ N++ Y++ S + + +T +K GV + T++ + Sbjct: 867 LPSSQNELENVFKAWGAANK-----YEYYKSSQT--IISWVQQTAQDAKSGVAS-TYDLV 918 Query: 1389 T 1389 Sbjct: 919 K 919 Score = 74.0 bits (181), Expect = 4e-15 Identities = 72/347 (20%), Positives = 114/347 (32%), Gaps = 46/347 (13%) Query: 905 KTTTELTFTVK----DAYGNPVTGLKPDAPVFSGAASTGSERPSAGNWTEKGNGVYVSTL 960 T TVK PV+ + SG A SA + G+G TL Sbjct: 575 TEAITYTATVKKNGVAQANVPVSFN-----IVSGTAV-----LSANSANTNGSGKATVTL 624 Query: 961 TLGSAAGQLSVMPRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVNNQLANGQSANQITL 1020 + +A+ V+ V D +KA I ++ +ANGQ A IT Sbjct: 625 KSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASITEIKADKTTAVANGQDA--ITY 680 Query: 1021 TVVDTY-GNPLQGQEVTLTLPQGVTSKTGNTVTTNAAGKADIELMSTVAGEHNISASVNG 1079 TV P+ QEVT T G S + T T+ G A + L ST G+ +SA V+ Sbjct: 681 TVKVMKGDKPVSNQEVTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSARVSD 738 Query: 1080 AQ---KTVTVKFNADASTGQANLQVDAAAQKVANGKDAFTLTANVEDKNGN-PVPGSLVT 1135 K V+F + N+++ V G T ++ N G Sbjct: 739 VAVDVKAPEVEFFTTLTIDDGNIEI------VGTGVKGKLPTVWLQYGQVNLKASGGNGK 792 Query: 1136 FNLPRGVKPLTGDNVWVKANDEGKAELQVVSVTAGTYEITASAGNSQPSNTQTITFVADK 1195 + N + + D QV GT I+ + ++Q T+ Sbjct: 793 YT-------WRSANPAIASVDASSG--QVTLKEKGTTTISVISSDNQT-----ATYTIAT 838 Query: 1196 ATATVSGIEVIGNYALADGNAKQTYKVTVTDANNNLLKDSEVTLTAS 1242 + + + D ++ N L++ A+ Sbjct: 839 PNSLIV-PNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAA 884 Score = 51.2 bits (122), Expect = 3e-08 Identities = 71/405 (17%), Positives = 126/405 (31%), Gaps = 56/405 (13%) Query: 768 NGQNAAANAAKVTVVADALSSNQSKV---SVAEDHVKAGESTTVTLVA------KDAHGN 818 NG ++ +TV+++ +Q V + + KA + +T A Sbjct: 535 NGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANV 594 Query: 819 AISGLALSASLTGTASEGATVSSWTEKGNGSYVATLTTGGKTGELRVMPLFNGQPAATEA 878 +S +S GTA A +S G+G TL + + A Sbjct: 595 PVSFNIVS----GTAVLSA--NSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALN-- 646 Query: 879 AQLTVIAGEMSSANSTLVADNKAPTVKTTTELTFTVKDAY-GNPVTGLKPDAPVFSGAAS 937 A + + ++ + + AD +T+TVK PV+ + + Sbjct: 647 ANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEV-------TFT 699 Query: 938 TGSERPSAGNWTEKGNGVYVSTLTLGSAAGQLSVMPRVNGQN-AVAQPLVLNVAG---DA 993 T + S NG TLT + G+ V RV+ V P V D Sbjct: 700 TTLGKLSNSTEKTDTNGYAKVTLT-STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDD 758 Query: 994 SKAEIRDMTVK---VNNQLANGQSANQI-------TLTVVDTYGNPLQGQEVTLTLPQGV 1043 EI VK L GQ + T + + +TL Sbjct: 759 GNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTL---- 814 Query: 1044 TSKTGNTVT---------TNAAGKADIELMSTVAGEHNISASVNGAQKTVTVKFNADAST 1094 K T++ T + ++ ++ + +VN + + Sbjct: 815 KEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKL--PSSQN 872 Query: 1095 GQANLQVD-AAAQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNL 1138 N+ AA K K + T+ + V+ + G T++L Sbjct: 873 ELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVASTYDL 917 Score = 44.3 bits (104), Expect = 4e-06 Identities = 53/303 (17%), Positives = 91/303 (30%), Gaps = 63/303 (20%) Query: 1035 VTLTLPQGVTSKTGNTVTTNAAGKADIELMSTVAGEHNISASVNGAQKTVTVKFNADAST 1094 ++L +P + +T K+ L V + + + G Q ++ + S Sbjct: 454 LSLNIPHDINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQ--GGQ----IQHSGSQSA 507 Query: 1095 GQANLQVDAAAQKVANGKDAFTLTANVEDKNGNPVPGSLVTFNLPRGVKPLTGDNVWVKA 1154 + A Q +N + +TA D+NG Sbjct: 508 QDYQAILPAYVQGGSN---VYKVTARAYDRNG---------------------------- 536 Query: 1155 NDEGKAELQVVSVTAGTYEITASAGNSQPSNTQTITFVADKATATVSGIEVIGNYALADG 1214 N L + ++ G + F ADK + A ADG Sbjct: 537 NSSNNVLLTITVLSNGQVVDQVGVTD----------FTADKTS------------AKADG 574 Query: 1215 NAKQTYKVTVTDANNNLLKDSEVTLTASPANLVLTPNGTAKTNEQGQAIFTATTTVAAKY 1274 TY TV S + +A TN G+A T + + Sbjct: 575 TEAITYTATVKKNGVAQANVPVSFNIVS--GTAVLSANSANTNGSGKATVTLKSDKPGQV 632 Query: 1275 TLTAKVSQADGQESTKTAESKFVADDTNAVLTASSDVTSLVADGISTAKLEVTLMSANNP 1334 ++AK A+ + FV ++ +D T+ VA+G V +M + P Sbjct: 633 VVSAK--TAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKP 690 Query: 1335 VGG 1337 V Sbjct: 691 VSN 693
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.029 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 14 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 55 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.002 Identities = 13/48 (27%), Positives = 22/48 (45%) Query: 33 IDGAAFRVGAGVQADITKNMGAYASLDYTKGDDIENPLQGVVGINVTW 80 + G +G G+ A + + YAS +Y+KG + P G +W Sbjct: 863 LRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.012 Identities = 20/109 (18%), Positives = 42/109 (38%), Gaps = 4/109 (3%) Query: 257 ASAQGTGSATQNLNLSVADSTIYSDVLALSESENSAATTTNVNMNVARSYWEGNAYTFNS 316 A+ +A+ + + T + + + TT ++ S+ N Sbjct: 761 ANITSNITASNKAQVHIGYKTGDTVCVRSDYTGYVTCTTDKLSDKALNSF---NPTNLRG 817 Query: 317 GDKAGSNLDINLSDSSVWKGKVSGAGNASVSLQNESVWNVTGSSTVDAL 365 + + L ++++ G + GN+ V L S W++TG+S V L Sbjct: 818 NVNLTESANFVLGKANLF-GTIQSRGNSQVRLTENSHWHLTGNSDVHQL 865
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.0 bits (158), Expect = 3e-15 Identities = 32/172 (18%), Positives = 59/172 (34%), Gaps = 15/172 (8%) Query: 10 RRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLR 69 R+ ++D L ++ G+ ++ +IA+ AGV+ G I +F+DK+ L S + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 DAVLNRLHALPQGSAEQRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQP-------ML 122 + L P G L+ I+ + T V+ + + Sbjct: 72 ELELEYQAKFP-GDPLSVLREILIHVLEST-VTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 123 YRLQQVSSRRLLSNLVSEFRRE---LPRHQAQEAGYGLAALIDGL---WLRA 168 R + S + + + A + I GL WL A Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 132 bits (333), Expect = 2e-33 Identities = 146/614 (23%), Positives = 232/614 (37%), Gaps = 97/614 (15%) Query: 758 GTLNGSADSLLSLNGGSLTVTNG------GTSTGSLTGSGELNIQGGTL----------- 800 G + LS G++ T G + S+T + QG L Sbjct: 326 GARVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKL 385 Query: 801 ----------DIAGDNSNLTANVNIANSANVLVSHAQGLGSANVENNGTLALNNSAEKRA 850 DI +I L S A+ G+ + +L+++N+ Sbjct: 386 TLTGGADAQGDIVATELPSIPGTSIGPLDVALASQARWTGATRAVD--SLSIDNATWVMT 443 Query: 851 AASVNYALGGNLTNNGTLMTGMSGQQAGNVLVVKGNYHGNNGQLVMNTVLNGDDSVTDKL 910 S AL L ++G++ + AG V+ N +G MN D ++DKL Sbjct: 444 DNSNVGAL--RLASDGSVDFQQPAE-AGRFKVLTVNTLAGSGLFRMNV--FADLGLSDKL 498 Query: 911 VVEGDTSGTTAVTVNNAGGTGAKTLNGIELIHVDGKSEGEFVQA---GRIVAGAYDYTLA 967 VV D SG + V N+G + N + L+ S F A G++ G Y Y LA Sbjct: 499 VVMQDASGQHRLWVRNSGS-EPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRLA 557 Query: 968 RGQGANSGNWYLTSGSDSPELQPEPDPMPNPEPNPNPEPN-PNPTPTPGPDLNVDNDLRP 1026 +G W L P +P P P P P P P+P P P P G +L+ Sbjct: 558 ---ANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELS------- 607 Query: 1027 EAGSYIANLAAANTMFTTRLHERLGNTYYTDMVTGEQKQTTMWMRHEGGHNKWRDGSGQL 1086 AAAN T +Y + ++ + + + G W G Q Sbjct: 608 ---------AAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAG-GAWGRGFAQR 657 Query: 1087 KTQSNRYV---------LQLGGDVAQWSQNGSDRWHVGVMAGYGNSDSKTISSRTGYRAK 1137 + NR +LG D A G RWH+G +AGY D G+ Sbjct: 658 QQLDNRAGRRFDQKVAGFELGADHAVAVAGG--RWHLGGLAGYTRGDRGFTGDGGGH--- 712 Query: 1138 ASVNGYSTGLYATWYADDESRNGAYLDSWAQYSWFDN--TVKGDDLQS--ESYKSKGFTA 1193 + G YAT+ AD +G YLD+ + S +N V G D + Y++ G A Sbjct: 713 --TDSVHVGGYATYIAD----SGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGA 766 Query: 1194 SLEAGYKHKLAEFNGSQGTRNEWYVQPQAQVTWMGVKADKHRESNGTLVHSNGDGNVQTR 1253 SLEAG + A + W+++PQA++ +R +NG V G +V R Sbjct: 767 SLEAGRRFTHA---------DGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGR 817 Query: 1254 LGVKTWLKSHHKMDDGKSREFQPFVEVNWLHNSKDFST-SMDGVSVTQDGARNIAEIKTG 1312 LG L+ +++ R+ QP+++ + L T +G++ + AE+ G Sbjct: 818 LG----LEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLG 873 Query: 1313 VEGQLNANLNVWGN 1326 + L +++ + Sbjct: 874 MAAALGRGHSLYAS 887
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.004 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 6 TEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRMETGLDVVLFTRS 55 E L+ A G+ KAA+ LGL + + I+ + G+ V +RS Sbjct: 436 MEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL--GVSVYRSSRS 483
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 338 bits (868), Expect = e-113 Identities = 122/401 (30%), Positives = 200/401 (49%), Gaps = 54/401 (13%) Query: 164 DLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSP 223 A +A G + Y ++ + + +L ++ ++G+S Sbjct: 88 MTAIKASEKGAYDYLPKPFDL--TELIGIIGRALAEPKRRPSK-LEDDSQDGMPLVGRSA 144 Query: 224 QMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNC 283 M+++ + + ++ ++I GE+GTGKEL A+A+H + R+ PFVA+N Sbjct: 145 AMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD-----YGKRRNG---PFVAINM 196 Query: 284 GAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVL 343 AI L+E+ELFG+E+GAFTG++ G FE A GGTLFLDEIG+MP+ QTRLLRVL Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 344 EEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGQFRRDLFYRLSILRLQLPPLRERVA 403 ++ E T VGG P+ DVR+++AT+ +L++ + QG FR DL+YRL+++ L+LPPLR+R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 404 DILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRELRNMMERLALFLS 463 DI L F++ ++ L+ + + WPGN+REL N++ RL Sbjct: 316 DIPDLVRHFVQ-QAEKEGLDVKRFDQEALEL----MKAHPWPGNVRELENLVRRLTALYP 370 Query: 464 VEP-TPDLTPQFLQLLLPELARESAKIPAPRLLTP------------------------- 497 + T ++ L+ +P+ E A + L Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYD 430 Query: 498 -----------QQALEKFNGDKTAAANYLGISRTTFWRRLK 527 AL G++ AA+ LG++R T ++++ Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.023 Identities = 11/33 (33%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 65 LIHGKLPTRDE-LAAYKTKLKALRGLPANVRTV 96 + +LPT +E AYK ++ + G P +RT+ Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTL 335
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 28.3 bits (63), Expect = 0.023 Identities = 24/125 (19%), Positives = 53/125 (42%), Gaps = 22/125 (17%) Query: 82 FYANFN----LTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNN 137 F A+F ++ + + V+I P+V ++T +++ + Y F +++ + Sbjct: 30 FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTIT--VRSYDMLNEEQYYQFFLSV-LD 86 Query: 138 VWIGSHVVINPGVTI---------------GDNSVIGAGSIVTKDIPPNVVAAGVPCRVI 182 V+ + + +N GV D + +VT+ +P VAA ++ Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 183 REIND 187 R++ND Sbjct: 147 RQLND 151
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 2e-04 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 22/192 (11%) Query: 4 LKNTNFWMFGLFFFFYFFI-MGAYFPFFPIWLHDINHISK--SDTGIIFAAISLFSLLFQ 60 +K + L + +G P P L D+ H + + GI+ A +L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 61 PLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNA 120 P+ G LSD+ G R LL + + I P L + + +G IV GI A Sbjct: 61 PVLGALSDRFGRRPVLL---VSLAGAAVDYAIMATAPFL-WVLYIGRIVAGIT-----GA 111 Query: 121 GAPAVEAFIEKVSRRSNFEFGRARMFG----CVGWALCAS--IVGIMFTINNQFVFWLGS 174 A+I ++ RAR FG C G+ + A + G+M + F+ + Sbjct: 112 TGAVAGAYIADITDGDE----RARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAA 167 Query: 175 GCALILAILLFF 186 + + F Sbjct: 168 ALNGLNFLTGCF 179
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 2e-05 Identities = 62/399 (15%), Positives = 122/399 (30%), Gaps = 31/399 (7%) Query: 38 VNYVLPALQTDLGLD---KGDIGLLGSLFYLSYGLSKFTAGLWHDSHGQRGFMGVGLFAT 94 + VLP L DL G+L +L+ L G D G+R + V L Sbjct: 24 IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGA 83 Query: 95 GLLNVVFAFGESLTLLLVVWTLNGFFQGWGWPPCARLLTHWYSRNERGFWWGCWNMSINI 154 + + A L +L + + G G + +ER +G + Sbjct: 84 AVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 155 GGAIIPLISAFAAHWWGWQAAMLTPGIISMALGIWLTLQLKGTPQEEGLPTVGHWRHDPL 214 G P++ + A ++ + L + + E P Sbjct: 143 GMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP---------- 191 Query: 215 ELRQEQQSPPMGLWQMLRTTMLQNPLIWLLGVSYVLVYVIRIALNDWGNIWLTESHGVNL 274 LR+E +P R + L+ V +++ V ++ W + + Sbjct: 192 -LRREALNPLAS----FRWARGMTVVAALMAVFFIMQLVGQVPAALWV---IFGEDRFHW 243 Query: 275 LSANATVMLFEVGGLLGALFAGWGSDLLFSGQRAPMILLFTLGLMVSVAALWLAPVHHYA 334 + + L G+L +L + + + L+ + + L + Sbjct: 244 DATTIGISL-AAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 335 LLAVCFFTVGFFVFGPQMLIGLAAVECGHK--AAAGSITGFLGLFAYLGAALAGWPLSLV 392 + + P + L+ + GS+ L + +G L + Sbjct: 303 AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 393 IERYGWPGMFSLLSVAAVLMGLLLMPLLMAGITTTHARR 431 I W G +A + LL +P L G+ + +R Sbjct: 363 ITT--WNG---WAWIAGAALYLLCLPALRRGLWSGAGQR 396
>PF06580#Sensor histidine kinase Length = 349 Score = 49.5 bits (118), Expect = 1e-08 Identities = 42/205 (20%), Positives = 79/205 (38%), Gaps = 43/205 (20%) Query: 337 QSQLVKRARDPAQIQSAASQIN-------------------ELARRIHLSTRQLLR-QLR 376 Q ++ A++ AQ+ + +QIN AR + S +L+R LR Sbjct: 151 QWKMASMAQE-AQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209 Query: 377 PPALDELTFREALLHL-----INEFAFSERGIHCQFAYQLNSTPENETVRFTLYRLLQEL 431 +++ + L + + F +R ++ P V+ L+Q L Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDR-----LQFENQINPAIMDVQVPPM-LVQTL 263 Query: 432 LNNICKHA-----EASEVTIILRQQGEVLHLEVSDNGVGIA--SGKMAGFGIQGMRERVS 484 + N KH + ++ + + + LEV + G + + G G+Q +RER+ Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQ 323 Query: 485 ALGGD---LTLE-KQHGTRVIVNLP 505 L G + L KQ +V +P Sbjct: 324 MLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 3e-17 Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 4/116 (3%) Query: 2 IRVVLVDDHVVVRSGFAQLLSLED-DLEVIGQYSSAAQAWSALIRDDVNVAVIDIAMPDE 60 +++ DD +R+ Q LS D+ + +AA W + D ++ V D+ MPDE Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITS---NAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLSLLKRLRAQKPQFRAIILSIYDAPTFVQSALDAGASGYLTKRCGPEELVQAVR 116 N LL R++ +P +++S + A + GA YL K EL+ + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 78.6 bits (193), Expect = 8e-17 Identities = 75/318 (23%), Positives = 115/318 (36%), Gaps = 56/318 (17%) Query: 584 TINGNGDNDNTASIEAGQNEVDNNGDHVAAATGNYKVRIDNATGAGSIADYNGNELIYVN 643 T+ G+G + G ++ A+G +++ + N+ GS L+ Sbjct: 477 TLAGSGLFRMNVFADLGLSDKLVVMQD---ASGQHRLWVRNS---GSEPASANTLLLVQT 530 Query: 644 DKNSNATFSAAN---KADLGAYTYQAEQRGNTV--------------------------- 673 S ATF+ AN K D+G Y Y+ GN Sbjct: 531 PLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQ 590 Query: 674 ---------VLQQMELTDYANMALSIP--SANTNIWNLEQDTVGTRLTNSRHGLADNGGA 722 EL+ AN A++ + +W E + + RL R D GGA Sbjct: 591 PQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRL-NPDAGGA 649 Query: 723 WVSYFGGNFNGDNGTIN-YDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMN---DR 778 W F DN +DQ V G +G D + +W +G AG+ +GD D Sbjct: 650 WGRGFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDG 709 Query: 779 SGQVDQDSQTAYIYSSAHFANNVF-VDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGF 837 G D Y + + A++ F +D +L S ND S+G V G + G Sbjct: 710 GGHTDSVHVGGY---ATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGA 766 Query: 838 GLKAGYDFKLGDAGYVTP 855 L+AG F D ++ P Sbjct: 767 SLEAGRRFTHADGWFLEP 784
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 68.7 bits (168), Expect = 1e-14 Identities = 38/183 (20%), Positives = 88/183 (48%), Gaps = 5/183 (2%) Query: 433 IQIVEERTIGPTLGMQNIEQGLEACLAGLLVSILFMII-FYKKFGLIATSALIANLILIV 491 ++I ++GP + + + + + LA +V + ++ + F +F L A AL+ +++L V Sbjct: 135 LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTV 194 Query: 492 GIMSLLPGATLSMPGIAGIVLTLAVAVDANVLINERIKEEL--SNGRTVQQAIDEGYRGA 549 G+ ++L + +A ++ +++ V++ +R++E L ++ ++ Sbjct: 195 GLFAVL-QLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 550 FSSIFDANITTLIKVIILYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKR 609 S +TTL+ ++ + G I+GF GV T ++++ + IV L G R Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV-LFIGLDR 312 Query: 610 VKK 612 K+ Sbjct: 313 NKE 315
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 350 bits (899), Expect = e-123 Identities = 104/309 (33%), Positives = 179/309 (57%), Gaps = 12/309 (3%) Query: 17 YDFMRWDYWAFGISGLLLIAAIVIMGVRGFNWGLDFTGGTVIEITLEKPAEIDVMRDALQ 76 +DF RW + FG + +++IA++++ V G N+G+DF GGT I ++ V R AL+ Sbjct: 14 FDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAALE 73 Query: 77 KAGFEEPMLQNFGS------SHDIMVRMPPAEGETGGQVLGSQVLKVINE------STNQ 124 + ++ H M+R+ E G + G+Q +++N+ + + Sbjct: 74 PLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDP 133 Query: 125 NAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVYVGFRFEWRLAAGVVIALAHDVIIT 184 + E VGP V +L T +L+AA + I+ Y+ RFEW+ A G V+AL HDV++T Sbjct: 134 ALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLT 193 Query: 185 LGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVSDRIRENFRKIRRGTPYEIFNVSLTQT 244 +G+ ++ ++ DLT VA+L+++ GYS+ND++VV DR+REN K + ++ N+S+ +T Sbjct: 194 VGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNET 253 Query: 245 LHRTLITSGTTLMVILMLYLFGGPVLEGFSLTMLIGVSIGTASSIYVASALALKLGMKRE 304 L RT++T TTL+ ++ + ++GG V+ GF M+ GV GT SS+YVA + L +G+ R Sbjct: 254 LSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRN 313 Query: 305 HMLQQKVEK 313 + +K Sbjct: 314 KEKKDPSDK 322
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 403 bits (1036), Expect = e-146 Identities = 200/218 (91%), Positives = 207/218 (94%) Query: 1 MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLE 60 MKKTLLAAGAV+ALS++F AAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLE Sbjct: 1 MKKTLLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLE 60 Query: 61 YEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEIEPRFSIDKLTNTDLSFGP 120 YEAFAKKDWFDFYGY DAPVFFGGNS AKGIWN GSPLFMEIEPRFSIDKLTNTDLSFGP Sbjct: 61 YEAFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGP 120 Query: 121 FKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMSLSMNVYAKYQWQNYGAANEN 180 FKEWYFANNYIYDMGRN QSTWYMGLGTDIDTGLPMSLS+NVYAKYQWQNYGA+NEN Sbjct: 121 FKEWYFANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYGASNEN 180 Query: 181 EWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG 218 EWDGYRFK+KYFVP+TDLWGG LSYIGFTNFDWGSDLG Sbjct: 181 EWDGYRFKVKYFVPLTDLWGGSLSYIGFTNFDWGSDLG 218
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 2e-05 Identities = 40/251 (15%), Positives = 77/251 (30%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDAWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALS-MLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 29.0 bits (65), Expect = 0.021 Identities = 11/43 (25%), Positives = 19/43 (44%) Query: 38 GQLAAVAIVTSDGNVYSAGDSDYRFALESISKVCTLALALEDV 80 G++ + + + G +A +D RF + S KV L V Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.006 Identities = 22/165 (13%), Positives = 57/165 (34%), Gaps = 20/165 (12%) Query: 199 DELQAQTRIAGMRSTLEQYQAQMASAKAQLAVLTGVQPEAIAAP----PAELAEQPVSLK 254 L A+ +S+L Q + + + + + + P ++E+ V Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL-- 185 Query: 255 NIDYQSIPLVLAAENLRQSAQYGVEKTKAQYWPTLSIQGGKTRYQTSDRSYWDDQLQLNV 314 + L+ + Q+ +Y E + R + ++ +L+ Sbjct: 186 ----RLTSLIKEQFSTWQNQKYQKELNLDKK--RAERLTVLARINRYENLSRVEKSRLDD 239 Query: 315 NAPLYQGGAVS--------AQVQQAEGQQKISASQVEQAKLDVLQ 351 + L A++ + +A + ++ SQ+EQ + ++L Sbjct: 240 FSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILS 284
>INTIMIN#Intimin signature. Length = 939 Score = 37.4 bits (86), Expect = 5e-04 Identities = 63/372 (16%), Positives = 115/372 (30%), Gaps = 44/372 (11%) Query: 649 QTVTVTLNGQTYQGVVQPDGTWSVTVPAANVGALADGNA--TVTASVNDVAGNPSSVSRV 706 T+TV NGQ V D T A A ADG T TA+V ++V Sbjct: 544 LTITVLSNGQVVDQVGVTDFT------ADKTSAKADGTEAITYTATVKKNGVAQANVPVS 597 Query: 707 ALVDATPPVVTINPVATDNVINTPEHAQAQIISGTVTGAQAGDIVTVTLNNVDYTTVVDG 766 + + V++ N T+ ++ V A+ ++ + N + VD Sbjct: 598 FNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSAL--NANAVIFVDQ 655 Query: 767 SGNWSLGVPASVVSGLADGSYPVSVSVTDKAGNTGSQSLTVTVNTAAPLIGINSIAGDDV 826 + + A + +A+G ++ +V G+ + VT T + Sbjct: 656 TKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSN-------- 707 Query: 827 INASEKGADLQITGTSDQPVNTAITVTLNGQNYTTTTDASGNWSVTVPASAVTALGQANY 886 T +D +T+T + + + +V V A V Sbjct: 708 -----------STEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFF--TTL 754 Query: 887 TVTAAVTSDIGNSATASHNVLVDSALPGVTINPVATDDIINAAEAGVAQTISGQVTGAED 946 T+ +G V LP V + + + + + D Sbjct: 755 TIDDGNIEIVGTG--------VKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVD 806 Query: 947 GDTVTITL---GGNTYTATVGSN--LTWSVDVPAADIQALGNGDLTVNASVTNQNGNTGS 1001 + +TL G T + N T+++ P + I + +T N +V G Sbjct: 807 ASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGK 866 Query: 1002 GTRDITIDANLP 1013 N+ Sbjct: 867 LPSSQNELENVF 878 Score = 35.0 bits (80), Expect = 0.002 Identities = 81/416 (19%), Positives = 139/416 (33%), Gaps = 61/416 (14%) Query: 783 ADGSYPVSVSVTDKAGN-TGSQSLTVTVNTAAPLIGINSIAGDDVINASEKGADLQITGT 841 Y V+ D+ GN + + LT+TV + + D + + AD GT Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITV-LSNGQVVDQVGVTDFTADKTSAKAD----GT 575 Query: 842 SDQPVNTAITVTLNGQNYTTTTDASGNWSVTVPASAVTALGQANYTVTAAVTSDIGNSAT 901 AIT YT T +G VP S G A + +A T + + Sbjct: 576 ------EAIT-------YTATVKKNGVAQANVPVSFNIVSGTAVLSANSANT-----NGS 617 Query: 902 ASHNVLVDSALPGVTINPVATDDIINAAEAGVAQTISGQVTGAEDGDTVTITLGGNTYTA 961 V + S PG + T ++ +A A A Q I T A Sbjct: 618 GKATVTLKSDKPGQVVVSAKTAEMTSALNAN-AVIFVDQTK----ASITEIKADKTTAVA 672 Query: 962 TVGSNLTWSVDVPAADIQALGNGDLTVNASVTNQNG----NTGSGTRDITIDANLPG--- 1014 +T++V V D + + N ++T ++ + +G +T+ + PG Sbjct: 673 NGQDAITYTVKVMKGD-KPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSL 731 Query: 1015 --LRVDTVAGDDVVNIIEHGQALVVTGSS-----SGLAESTP----------LTVTINNV 1057 RV VA D +E L + + +G+ P L + N Sbjct: 732 VSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNG 791 Query: 1058 EYTTAVQADGSWSVGVTAAQVSAWPAGTVNIAVSGESSAGNSVSITHPVTVDLTPAAITI 1117 +YT SV ++ QV+ GT I+V + + +I TP ++ + Sbjct: 792 KYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIA-------TPNSLIV 844 Query: 1118 NTIATDDVINAAEKGADLTLSGTTTNVEPGQTVTVTFGGKNYTASVASDGSWTATV 1173 ++ N A ++ + V +G N S + + V Sbjct: 845 PNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWV 900
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 44.6 bits (105), Expect = 9e-06 Identities = 43/221 (19%), Positives = 68/221 (30%), Gaps = 12/221 (5%) Query: 4539 GTASNNGKFVGTGYNDTFFATAGTDTYDGSGGWVYSSGTGTWLANGGMDVVDFRLSTVGV 4598 T + F D + AT + S + T + ++ + Sbjct: 265 RTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSD 324 Query: 4599 TANLSSTAAQATGFNTSTFTNIEGISGSNFNDILTGSSGDNQLEGRGGNDTLNIGNGGHD 4658 L + A G IE G + NDIL G+S DN L+G GND L G G Sbjct: 325 VGGLKGNVSIAHG------VTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAG--A 376 Query: 4659 TLLYKLLNASDATGGNGSDVVNGFTVGTWEGTADTDRIDIRELLQGSGYTG-NGKASYVN 4717 LY G+G D + D+ID+ + + + Sbjct: 377 DTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLSAFRNEGQLSFVQDQFTGKG 436 Query: 4718 GVATLDAQAGNIGDFVKVTQS---GSDTIVQIDRDGTGGTF 4755 L A N + + ++ D +V+I Sbjct: 437 QEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQAAQSDI 477
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 5e-19 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%) Query: 16 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFT--GVLIDLDS 69 K ITG + GIG A L QG H+ A P+ +E++ S D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRRSGIKVSLIEP 189 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 54.7 bits (132), Expect = 1e-10 Identities = 39/163 (23%), Positives = 59/163 (36%), Gaps = 32/163 (19%) Query: 4 DLIIKNGTVILENEARVVDIAVKGGKIAAIG-------QD-----LGDAKEVMDASGLVV 51 D +I N ++ DI +K G+IAAIG Q +G EV+ G +V Sbjct: 69 DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 52 SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104 + G +D+H H P + A G+T M+ PA A+ Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177 Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146 I +AA ++ A G + L E+ G K Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 381 bits (980), Expect = e-136 Identities = 125/310 (40%), Positives = 174/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PPVTTVRTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T+ T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTDDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGMPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285 +G +++ +R +EL + + GSMGPKV A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 744 bits (1923), Expect = 0.0 Identities = 372/876 (42%), Positives = 535/876 (61%), Gaps = 88/876 (10%) Query: 11 QRYTWCL------AGICYSSLAILPSFLSY-----AESYFNPAFLLENGTFVADLSRFER 59 QR T CL + L + +F + AE YFNP FL ++ VADLSRFE Sbjct: 10 QRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFEN 69 Query: 60 GNHQPAGVYRVDLWRNDEFIGSQDIVFESTTENTGDKSGGLMPCFNQVLLERIGLNSSAF 119 G P G YRVD++ N+ ++ ++D+ F NTGD G++PC + L +GLN+++ Sbjct: 70 GQELPPGTYRVDIYLNNGYMATRDVTF-----NTGDSEQGIVPCLTRAQLASMGLNTASV 124 Query: 120 PELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIALLSSAHGYIPPEEWDEGIPA 179 + ++ C+ L + DAT D RLN+TIPQ + + A GYIPPE WD GI A Sbjct: 125 SGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINA 184 Query: 180 LLLNYNFTGN----RGNGNDSYFFSEL-SGINIGPWRLRNNGSWNYFRGNG--YHSEQWN 232 LLNYNF+GN R GN Y + L SG+NIG WRLR+N +W+Y + +W Sbjct: 185 GLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQ 244 Query: 233 NIGTWVQRAIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDNMYPDSQQGFAPTVRGI 292 +I TW++R IIPL+S L +GDG T DIFDG+ FRG +L S DNM PDSQ+GFAP + GI Sbjct: 245 HINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGI 304 Query: 293 ARTAAQLTIRQNGFIIYQSYVSPGAFEITDLHPTSSNGDLDVTIDERDGNQQNYTIPYST 352 AR AQ+TI+QNG+ IY S V PG F I D++ ++GDL VTI E DG+ Q +T+PYS+ Sbjct: 305 ARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSS 364 Query: 353 VPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGLPQEFTAYGGTQLSANYTAFL 412 VP+LQREG ++ +TAG++RSGN+QQ P FFQ T L GLP +T YGGTQL+ Y AF Sbjct: 365 VPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFN 424 Query: 413 LGLGRNLGNWGAVSLDVTHARSQLADDSRHEGDSIRFLYAKSMNTFGTNFQLMGYRYSTQ 472 G+G+N+G GA+S+D+T A S L DDS+H+G S+RFLY KS+N GTN QL+GYRYST Sbjct: 425 FGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTS 484 Query: 473 GFYTLDDVAYRRMEGYEYDYDYDGEHRDEPIIVNYHNLRFSRKDRLQLNISQSLNDFGSL 532 G++ D Y RM GY DG + +P +Y+NL ++++ +LQL ++Q L +L Sbjct: 485 GYFNFADTTYSRMNGY-NIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTL 543 Query: 533 YISGTHQKYWNTSDSDTWYQVGYTSSWVGISYSLSFSWNESVGIPDNERIVGLNVSVPFN 592 Y+SG+HQ YW TS+ D +Q G +++ I+++LS+S ++ ++++ LNV++PF+ Sbjct: 544 YLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFS 603 Query: 593 VLTKRRYTRENALDRAYASFNANRNSNGQN----------------SWQLSGGVVGHENG 636 R ++ A AS++ + + NG+ S+ + G G +G Sbjct: 604 HWL--RSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDG 661 Query: 637 ---------ITLSQPLGDTN-------------------------------------VLI 650 + G+ N VL+ Sbjct: 662 NSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLV 721 Query: 651 KAPGAGGVRIENQTGILTDWRGYAVMPYATVYRYNRIALDTNTMGNSIDVEKNISSVVPT 710 KAPGA ++ENQTG+ TDWRGYAV+PYAT YR NR+ALDTNT+ +++D++ +++VVPT Sbjct: 722 KAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPT 781 Query: 711 QGALVRANFDTRIGVRALITVTQGGKPVPFGSLVRENSTGITSMVGDDGQVYLSGAPLSG 770 +GA+VRA F R+G++ L+T+T KP+PFG++V S+ + +V D+GQVYLSG PL+G Sbjct: 782 RGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAG 841 Query: 771 ELLVQWGDGANSRCIAHYVLPKQSLQQAVTVISAVC 806 ++ V+WG+ N+ C+A+Y LP +S QQ +T +SA C Sbjct: 842 KVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 7e-13 Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Query: 22 MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLP 81 M ++++ D IR + L + V T + ++ DL++ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 82 GTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMI 141 + F L RIK+ + + VL +S+++ A +A + GA ++ K D ++ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 142 LS 143 L+ Sbjct: 119 LA 120
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 64.5 bits (157), Expect = 5e-18 Identities = 18/52 (34%), Positives = 28/52 (53%) Query: 32 INMLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVLAYEPKK 83 + + + V+++CLT+L FT L SLCE ++ E A +AYE K Sbjct: 1 MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 275 bits (705), Expect = 7e-97 Identities = 105/183 (57%), Positives = 130/183 (71%), Gaps = 1/183 (0%) Query: 4 MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYA 63 M T+H LPFAGH LH V+FD ++F E DLLWLPH+ +L+ AGRKRK EHLAGRIAAV+A Sbjct: 1 MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA 60 Query: 64 LREYGYKCVPAIGELRQPVWPAEVYGSISHCGATALAVVSRQPIGVDIEEIFSAQTATEL 123 LRE G + VP +G+ RQP+WP ++GSISHC TALAV+SRQ IG+DIE+I S TATEL Sbjct: 61 LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL 120 Query: 124 TDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKA-SEIQTDAGFLDYQIISWNKQQV 182 +II E + L L F LALTLAFSAKES +KA S+ T GF ++ S + Sbjct: 121 APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI 180 Query: 183 IIH 185 +H Sbjct: 181 SLH 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 2e-04 Identities = 82/394 (20%), Positives = 145/394 (36%), Gaps = 38/394 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMP 309 A IG AA L + A+ +G +A ++L + ++ + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403 + A + + +G+ + L LL L LRR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 63.8 bits (155), Expect = 1e-13 Identities = 61/285 (21%), Positives = 101/285 (35%), Gaps = 35/285 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSTEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQA 154 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 155 L-----LTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERL 314 KD DA+ A PL +P V+ + + F SAM + L Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVL 288
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 444 bits (1142), Expect = e-161 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 362 bits (930), Expect = e-130 Identities = 110/258 (42%), Positives = 150/258 (58%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------------QAFAQEQYPFATE 49 GK ++TGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+A + ++ R+ E +D+LVN AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.8 bits (228), Expect = 1e-23 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVYEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATAAP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.012 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 785 LLENAVKYAGAQAE----IGIDAHVEGENLQLDVWDNGPGLPPGQEQT 828 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.4 bits (71), Expect = 0.003 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%) Query: 48 EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106 E+ + I+ ++ EG +V +L +L + +S +A R Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158 + L P + + T ++ E +L K A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 APAAAAPAAQPALAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215 A + + + L + A +LE +N V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 216 LRKQYGEAFEKRHGIR 231 + + A E+ + Sbjct: 278 IESEILSAKEEYQLVT 293
>PF03309#Bvg accessory factor Length = 271 Score = 33.6 bits (77), Expect = 0.001 Identities = 10/55 (18%), Positives = 23/55 (41%) Query: 3 IVSVDIGSTWTKAALFTREGDALTLVNHVLTPTTTHHLAKGFFSSLNQVLNVDNA 57 ++++D+ +T T L + GD +V T A +++ ++ D Sbjct: 2 LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDAE 56
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 54.3 bits (130), Expect = 6e-10 Identities = 33/215 (15%), Positives = 69/215 (32%), Gaps = 1/215 (0%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADDKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKK 185 +++ KQ + + A+ + + +E + A + A+ + E Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDP-TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184 Query: 186 AEAAAAALKKKAEAAEAAAAEARKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAAD 245 E E + +++ K + + + + A + Sbjct: 1185 ESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244 Query: 246 KKAAAAKAAAEKAAAAKAAAEADDIFGELSSGKNA 280 A + A + A A F L+ GK Sbjct: 1245 STVALCDLTSTNTNAVLSDARAKAQFVALNVGKAV 1279 Score = 53.9 bits (129), Expect = 7e-10 Identities = 26/169 (15%), Positives = 57/169 (33%), Gaps = 2/169 (1%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADDKAAEE 158 E E+ Q QA+ + + ++ + A +E + AE Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 159 AAKKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAAAEKAAA 218 + +++ +K E +A + A+ ++ A+ A + +K + E A + + K Sbjct: 1044 SKQESK--TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 219 DKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEA 267 + EK K +K K + ++ + A A Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Score = 52.0 bits (124), Expect = 3e-09 Identities = 23/162 (14%), Positives = 58/162 (35%), Gaps = 8/162 (4%) Query: 86 QQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADA 145 + AE +++ + K + + ++ A+EA + + E A + + Sbjct: 1038 ETVAENSKQESKTVE---KNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 146 KAKAEADDKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAA 205 E + A E +KA + +K E K ++ K E + + A E Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKT--QEVPKVTSQVSPKQEQSETVQPQAEPARENDPT 1152 Query: 206 EARKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 247 K+ ++ + A + A++ +++ + ++ Sbjct: 1153 VNIKEPQSQT---NTTADTEQPAKETSSNVEQPVTESTTVNT 1191 Score = 52.0 bits (124), Expect = 3e-09 Identities = 24/192 (12%), Positives = 66/192 (34%), Gaps = 5/192 (2%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAADAKAKAEADDKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKA 186 + ++ A+EA + A+ + E +E + + + KA E +K Sbjct: 1062 TAQNREVAKEAKSNVKANTQT-NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ 1120 Query: 187 EAAAAALKKKAEAAEAAAAEARKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADK 246 E + + ++ + + + A E E + AD + A++ +++ Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPT-VNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 247 KAAAAKAAAEKA 258 + ++ Sbjct: 1180 EQPVTESTTVNT 1191 Score = 51.6 bits (123), Expect = 4e-09 Identities = 31/187 (16%), Positives = 58/187 (31%), Gaps = 8/187 (4%) Query: 87 QAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAK 146 QA E R+ + A + E A+ KQ + K DA Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN----SKQESKTVEKNEQDAT 1059 Query: 147 AKAEADDKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKA--EAAAAALKKKAEAAEAAA 204 + + A+EA A+ + A++ E Q E A ++KA+ Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119 Query: 205 AEARKKAAAEKAAADKKAAEKAAAEKAAADKKA--AAEKAAADKKAAAAKAAAEKAAAAK 262 E K + ++ + AE A + E + A + A++ ++ Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 263 AAAEADD 269 + Sbjct: 1180 EQPVTES 1186 Score = 50.1 bits (119), Expect = 1e-08 Identities = 29/251 (11%), Positives = 84/251 (33%), Gaps = 19/251 (7%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAE--------EAAAKAAADAKAK---AEAD 152 + E + ++ ++ Q K+ +K+ + + K + K +E Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 153 DKAAEEAAKKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAA 212 AE A + K+ +++ A Q E ++ + E+ + + Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199 Query: 213 AEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADDIFG 272 A + + + ++ + ++ A ++ +++ A + + Sbjct: 1200 ENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNA 1259 Query: 273 ELSSGKNAPKT 283 LS + + Sbjct: 1260 VLSDARAKAQF 1270
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 29.0 bits (64), Expect = 0.012 Identities = 14/41 (34%), Positives = 30/41 (73%), Gaps = 2/41 (4%) Query: 36 KIALERRSKEREKAEKAEKAAEKKRRREEQKQKDKLKIQKL 76 K ALE+ + +E+A+KA+K +K+ +R+E++ K++ ++ L Sbjct: 145 KKALEKEKEAKEQAQKAQK--DKREKRKEERAKNRANLENL 183
>cloacin#Cloacin signature. Length = 551 Score = 43.9 bits (103), Expect = 3e-06 Identities = 34/142 (23%), Positives = 62/142 (43%), Gaps = 4/142 (2%) Query: 519 DQQRLNDLQEKKRQKDLQDAK--EQAERNYQEQQKRRNAENAALNRMNETEAARHQREIA 576 DQ + +E +RQ++ E AERNY+ + N N + R E +A Q + Sbjct: 294 DQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNS 353 Query: 577 RINAMQYADQAVRDA-AIQRENERYEKALASGKKKTRETRNDEATRLLLQYSQQQAQVEG 635 R + + A++ + DA A ++ R+ +G + + +A R + +QA + Sbjct: 354 RKSELDAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMAGLKAQRAQTDVNNKQAAFDA 413 Query: 636 QIAAARQSAGIATERMTEARKQ 657 A + A A E+RK+ Sbjct: 414 -AAKEKSDADAALSSAMESRKK 434
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 33.5 bits (76), Expect = 0.005 Identities = 34/143 (23%), Positives = 45/143 (31%), Gaps = 30/143 (20%) Query: 966 SVNANSGTLNNVTVNENCTIKGMLEATQV----RGDF---------VKAVSKSFPKQAGT 1012 + + L NVT + +K L+A ++ G F VKA S K A Sbjct: 235 AAQYDKKQLTNVTFDTETAVKDALKAQKIEVSSVGYFKAPHTFTVNVKATSNKNGKSATL 294 Query: 1013 WGNTETPNGTVTVTISDDHNFDRQIIIPPIIFNGIAYSDPGSGNNPGGTRYTGYGFEVRK 1072 PN V S I+ N Y + G R Sbjct: 295 PVTVTVPNVADPVVPSQSKT---------IMHNAYFYDKDA--------KRVGTDKVTRY 337 Query: 1073 NGVLIASRETKGAIPGSYSAVID 1095 N V +A TK A SY VI+ Sbjct: 338 NTVTVAMNTTKLANGISYYEVIE 360
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 87.3 bits (216), Expect = 2e-24 Identities = 45/140 (32%), Positives = 72/140 (51%), Gaps = 15/140 (10%) Query: 1 MRKVCAAILSAAICLAVSGVPAWASEHQSTLSAGYLHASTDAPG-SDDLNGINVKYRYEF 59 M+K+ AA+ +G A ST++ GY A +DA G + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAA---TSTVTGGY--AQSDAQGQMNKMGGFNLKYRYEE 55 Query: 60 TDT-LGLITSFSYANAEDEQKTHYSDTRWHEDYVRNRWFSVMAGPSVRVNEWFSAYAMAG 118 ++ LG+I SF+Y T S T DY +N+++ + AGP+ R+N+W S Y + G Sbjct: 56 DNSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVG 107 Query: 119 VAYSRVSTFSGDYFRVTDNK 138 V Y + T ++ + Sbjct: 108 VGYGKFQTTEYPTYKHDTSD 127
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.1 bits (75), Expect = 0.002 Identities = 36/130 (27%), Positives = 55/130 (42%), Gaps = 15/130 (11%) Query: 133 SARNAGISASKAEASAANADTSAEDASESARQAAESAASAKKSEEASSSSAS-------- 184 S G SK+E+SAA T+ ++ + AE AA AK + EA + + + Sbjct: 34 SGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQR 93 Query: 185 ------EAAQKASESLQSATDAELSKKTAESAAGNAARDATTSTEKARESAESAQSAEQS 238 EA + + SAT+ + A A R A + EKAR+ AE+A+ A Q Sbjct: 94 LKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLA-KAEEKARKEAEAAEKAFQE 152 Query: 239 RIAAEDAVNR 248 + R Sbjct: 153 AEQRRKEIER 162
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 28.9 bits (64), Expect = 0.027 Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 3/66 (4%) Query: 200 RMDKINGESLLNISSLPAQAEHAIYDMFDRLEQKGILFVDTTETNVLYDRAKNEFNPIDI 259 + KIN E+ A H + D+ + L + G++ D NV++DRA E ID+ Sbjct: 234 KQGKINSEAYWGTIKFIA---HRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDL 290 Query: 260 SSYNVS 265 ++ S Sbjct: 291 GLHSRS 296
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 31.8 bits (72), Expect = 0.003 Identities = 15/51 (29%), Positives = 26/51 (50%) Query: 232 VFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLKDASLDI 282 + + P + LSG V PV+ +P+ Q P+ H D+ + I L +D+ Sbjct: 184 LVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.008 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 240 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 299 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 300 KRGEIFG----LLGPNGAGKSTTFKMMCGL 325 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.7 bits (66), Expect = 0.037 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 39 YVTGLVGPDGAGKTTLMRMLAGL 61 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.9 bits (127), Expect = 4e-10 Identities = 36/203 (17%), Positives = 78/203 (38%), Gaps = 24/203 (11%) Query: 80 YEIALMQAKAGVSVAQAQYD-LMLTLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQA 135 E ++A + V ++Q + + + SA+++ + + + + Q ++ Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 136 QLAQAELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERN 193 +LA+ E Q S + AP + V G V+ T+ + + V A V ++ Sbjct: 317 ELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKD 376 Query: 194 LDQAQPGRKVLLYTDGRPDKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVV 250 + G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 377 IGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISI 428 Query: 251 T-------DADDALRQGMPVTVQ 266 + + L GM VT + Sbjct: 429 EENCLSTGNKNIPLSSGMAVTAE 451 Score = 48.3 bits (115), Expect = 1e-08 Identities = 24/157 (15%), Positives = 52/157 (33%), Gaps = 15/157 (9%) Query: 4 KPVVIGLAVVVLAAVVAGXYWWYQSRQDNGLTLYGNV--DIRTVNLSFRVGGRVESLAVD 61 +A ++ +V + + T G + R+ + V+ + V Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 62 EGDAIKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLTLKSAQDK----------- 110 EG++++ G VL +L E ++ ++ + A+ + L + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 111 --LRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQ 145 + + + K Q Q Q ELNL Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLD 210
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.1 bits (179), Expect = 6e-18 Identities = 33/214 (15%), Positives = 77/214 (35%), Gaps = 17/214 (7%) Query: 13 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 71 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 72 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQL 131 IGE E + P + +RE+++ + + + + + F E + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120 Query: 132 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 191 A + + + + + +A L T + + G Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173 Query: 192 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 225 L W + + + ++ ++L+ Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.025 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 31 LVLLGPSGAGKSSLLRVL 48 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 28.7 bits (64), Expect = 0.025 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 2 RRVFWLIAVALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADD 55 R+V L+ ALL AG A I K+G +LD Y ++ L HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 72.9 bits (179), Expect = 1e-16 Identities = 69/363 (19%), Positives = 122/363 (33%), Gaps = 65/363 (17%) Query: 13 MKVLVTGATSGLGRNAVEFLCQKXISVRA---------TGRNEAMGKLLEKMGAEFVPAD 63 MK LVTGA +G + + L + V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 64 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 116 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 117 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 176 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 177 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 234 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 235 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 280 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 281 MIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAW 340 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 341 LRD 343 RD Sbjct: 328 YRD 330
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.0 bits (83), Expect = 5e-04 Identities = 31/114 (27%), Positives = 46/114 (40%), Gaps = 4/114 (3%) Query: 177 NQLARVGGIDPLIGREKELERAIQVLCR--RRKNNPLLVGESGVGKTAIAEGLAWRIVQG 234 PL+GR ++ +VL R + ++ GESG GK +A L + Sbjct: 128 KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRR 187 Query: 235 DVPEVMADCTIYSLD-IGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEI 287 + P V + D I S L G + +G F + EQ LF+DEI Sbjct: 188 NGPFVAINMAAIPRDLIESELFGHE-KGAFTGAQTRSTGRFEQAEGGTLFLDEI 240
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.6 bits (56), Expect = 0.043 Identities = 6/15 (40%), Positives = 13/15 (86%) Query: 21 SQLLGISRSTIYEKM 35 + LLG++R+T+ +K+ Sbjct: 456 ADLLGLNRNTLRKKI 470
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1081 bits (2797), Expect = 0.0 Identities = 397/570 (69%), Positives = 462/570 (81%), Gaps = 2/570 (0%) Query: 1 MMSNISRQAYADMFGPTTGDKIRLADTELWIEVEDDLTTYGEEVKFGGGKVIRDGMGQGQ 60 M +SR AYA+MFGPT GDK+RLADTEL+IEVE D TT+GEEVKFGGGKVIRDGMGQ Q Sbjct: 1 MSYRMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQ 60 Query: 61 ML-SAGCADLVLTNALIIDYWGIVKADIGVKDGRIFAIGKAGNPDIQPNVTIPIGVSTEI 119 + G D V+TNALI+D+WGIVKADIG+KDGRI AIGKAGNPD+QP VTI +G TE+ Sbjct: 61 VTREGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEV 120 Query: 120 IAAEGRIVTAGGVDTHIHWICPQQAEEALTSGITTMIGGGTGPTAGSNATTCTPGPWYIY 179 IA EG+IVTAGG+D+HIH+ICPQQ EEAL SG+T M+GGGTGP G+ ATTCTPGPW+I Sbjct: 121 IAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIA 180 Query: 180 QMLQAADSLPVNIGLLGKGNCSNPDALREQVAAGVIGLKIHEDWGATPAVINCALTVADE 239 +M++AAD+ P+N+ GKGN S P AL E V G LK+HEDWG TPA I+C L+VADE Sbjct: 181 RMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADE 240 Query: 240 MDVQVALHSDTLNESGFVEDTLTAIGGRTIHTFHTEGAGGGHAPDIITACAHPNILPSST 299 DVQV +H+DTLNESGFVEDT+ AI GRTIH +HTEGAGGGHAPDII C PN++PSST Sbjct: 241 YDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSST 300 Query: 300 NPTLPYTVNTIDEHLDMLMVCHHLDPDIAEDVAFAESRIRQETIAAEDVLHDLGAFSLTS 359 NPT PYTVNT+ EHLDMLMVCHHL P I ED+AFAESRIR+ETIAAED+LHD+GAFS+ S Sbjct: 301 NPTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIIS 360 Query: 360 SDSQAMGRVGEVVLRTWQVAHRMKVQRGPLPEESGDNDNVRVKRYIAKYTINPALTHGIA 419 SDSQAMGRVGEV +RTWQ A +MK QRG L EE+GDNDN RVKRYIAKYTINPA+ HG++ Sbjct: 361 SDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLS 420 Query: 420 HEVGSIEVGKLADLVLWSPAFFGVKPATIVKGGMIAMAPMGDINGSIPTPQPVHYRPMFA 479 HE+GS+EVGK ADLVLW+PAFFGVKP ++ GG IA APMGD N SIPTPQPVHYRPMF Sbjct: 421 HEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFG 480 Query: 480 ALGSARHRCRVTFLSQAAAANGVAEQLNLHSTTAVVKGCR-TVQKADMRHNSLLPDITVD 538 A G +R VTF+SQA+ G+A +L + V+ R + KA M HNSL P I VD Sbjct: 481 AYGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVD 540 Query: 539 SQTYEVRINGELITSEPADILPMAQRYFLF 568 +TYEVR +GEL+T EPA +LPMAQRYFLF Sbjct: 541 PETYEVRADGELLTCEPATVLPMAQRYFLF 570
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 33.6 bits (77), Expect = 2e-06 Identities = 14/48 (29%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 1 MPQKTIIVGML--CLTMLLTVWVLHASPCEFRVSFMWSEIAAFLQCKP 46 +P+ +++ +L CLT+L+ ++ S CE R + E+AAF+ + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>PF02370#M protein repeat Length = 168 Score = 35.9 bits (82), Expect = 1e-04 Identities = 20/103 (19%), Positives = 47/103 (45%), Gaps = 3/103 (2%) Query: 18 EQAEALRQKDQQLSLVEETEAFLRSALARAEEKIEEEEREIEHLRAQIEKLRRMLFGTRS 77 + +++ R+ D Q + LR + ++KIEE E+E + + + E+ + + Sbjct: 38 DSSDSKRENDPQYRALMGENQDLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQD 97 Query: 78 EKLQREVEQAEAQLKQREQESDRYSGREDDPQVPRQLRQSRHR 120 + Q + ++ + + +Q E E + + Q+ RQ +R Sbjct: 98 KHYQEQQKKHQQEQQQLEAEKQKL---AKEKQISDASRQGLNR 137
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 29.7 bits (66), Expect = 0.028 Identities = 21/54 (38%), Positives = 29/54 (53%), Gaps = 4/54 (7%) Query: 314 KTDGVVTIHVPDQPPIETRLTEGENRRTLCAIARLVNE--NGAIK-VERINQYF 364 K D V + PDQ PI + + +NR+ I++L E N AIK + NQYF Sbjct: 31 KVDNAVASYDPDQKPIVDK-NDRDNRQAFEGISQLREEYSNKAIKNPTKKNQYF 83
>PF07824#Type III secretion chaperone Length = 120 Score = 28.0 bits (62), Expect = 0.014 Identities = 10/36 (27%), Positives = 15/36 (41%) Query: 132 VNDDNQTEVARYDLTEDASTETAMLFGELYRHNGEW 167 +D+ + +AR DLT E + E Y W Sbjct: 73 TDDEGGSLIARLDLTGINEFEDIYVNTEYYISRVRW 108
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 27.7 bits (61), Expect = 0.013 Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 5/61 (8%) Query: 74 VELLPVEITPDEQKEPVAAIAPSLSTSTQTSVSAGSCKVEFRHGNMTLENPSPELLTLLI 133 VE P +PDE P+ P+L T+ + ++L N +LT+ Sbjct: 40 VEGGPTVPSPDEPGLPLPGPGPALPTNGAIPIPEPGTAPA-----VSLMNMDGSVLTMWS 94 Query: 134 R 134 R Sbjct: 95 R 95
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 33.1 bits (75), Expect = 0.006 Identities = 100/488 (20%), Positives = 153/488 (31%), Gaps = 74/488 (15%) Query: 423 GTLAVSAGGKATSVT---ITSGGALI---ADSGATV---EGTNASGKFSIDGTSGQASGL 473 G +GG ++ I +GGA + ++ G +A GK + + L Sbjct: 326 GARVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKL 385 Query: 474 LLENG----GSFTVNAGGQAGNTTVGHRGTLTLAAGGSLSGRTQLSKGASMVLNGDVVST 529 L G G T++G + LA+ +G T+ S+ N V T Sbjct: 386 TLTGGADAQGDIVATELPSIPGTSIG-PLDVALASQARWTGATRAVDSLSID-NATWVMT 443 Query: 530 GDIVNAGEIRFDNQTTPNAALSRAVAKSNSPVTFHKLTTTNLTGQGGTINMRVRLDGSNA 589 + N G +R + S + F LT L G G M V D Sbjct: 444 DN-SNVGALRLASDG------SVDFQQPAEAGRFKVLTVNTLAGSG-LFRMNVFAD-LGL 494 Query: 590 SDQLVINGGQATGKTWLAFTNVGNSNLGVATTGQGIRVVDAQNGATTEEGAFALSRPLQA 649 SD+LV+ A+G+ L N G+ T + +V G+ + Sbjct: 495 SDKLVVMQD-ASGQHRLWVRNSGSEPASANT----LLLVQTPLGSAATFTLANKDGKVDI 549 Query: 650 GAFNYTLNRDSDEDWYLRSENAYRAEVPLY-----------------------TSMLTQA 686 G + Y L + + W L A A P L+ A Sbjct: 550 GTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAA 609 Query: 687 MDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEG 746 + G T E+N++ + L D G RG R Sbjct: 610 ANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGR--- 666 Query: 747 DLLRTEVAGMSL--------TTGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLV 798 +VAG L G + G + D + G D+ +GGY + Sbjct: 667 -RFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYI 725 Query: 799 HTSSGLWADIVAQGTRHSMKASSDNND-------FRARGWGWLGSLETGLPFSITDNLML 851 SG + D + +R +D +R G G SLE G F+ D L Sbjct: 726 -ADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGA--SLEAGRRFTHADGWFL 782 Query: 852 EPQLQYTW 859 EPQ + Sbjct: 783 EPQAELAV 790
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 66.4 bits (162), Expect = 6e-19 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 23 QKAMLIALIVICLTVIVTALVTRKDLCEVRVRTGQTEVAVFTAYEP 68 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 138 bits (350), Expect = 4e-44 Identities = 61/200 (30%), Positives = 98/200 (49%), Gaps = 30/200 (15%) Query: 1 MRKLYAAILSAAICLAVSGAPAWASEQQATLSAGYLHARTSAPGSDNLNGINVKYRYEFT 60 M+K+ AA+ +G + +T++ GY + + + G N+KYRYE Sbjct: 1 MKKIACLSALAAVLAFTAGT---SVAATSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGLVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGV 119 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.4 bits (94), Expect = 8e-06 Identities = 47/289 (16%), Positives = 91/289 (31%), Gaps = 30/289 (10%) Query: 11 LKDGTGKPVENCTIQLKARRNSATVVVNTVASENPDE-AGRYSMDVEYGQYSVILLVEGF 69 + D TG+P N A + + ++ D A +Y + G+Y + + Sbjct: 928 VADKTGEPNHNELTLFDASKAQRDHLNVSLVGNTVDLGAWKYKLRNVNGRYDL------Y 981 Query: 70 PPSHAGTITVYEDSQPGTLNDFLGAMSEDDVRPEALRRFELMVEEAARHAEEAKKNAGEA 129 P + + T N+ + E + R + A ++ Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSE----TT 1037 Query: 130 ETSARNAGISASQAEESAANADTSAGDASESARQAA-ESAAAAKQSEEASSSSASAAAQK 188 ET A N+ + E++ +A + E A++A A + +E A S S + Q Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 189 ASESSQSAAEA------------ELSKKTAESAAGNAARDAT-TATEKARE-----SAES 230 + E E+ K T++ + + E ARE + + Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 231 AQSAEQSRIAAEEAVNRIPTVVGPPGPKGEPGPAGPQGPKGDKGERGDT 279 QS + E+ + V P + G + + T Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 27.4 bits (61), Expect = 0.014 Identities = 18/66 (27%), Positives = 26/66 (39%), Gaps = 7/66 (10%) Query: 57 IMLAQHALLIAISSDLNAYGVVCEFDWN----DGNGQEGWPSMDGSEGIRITD---IDTS 109 + LA L I + D +G +F DG GQ G+ IT+ +D Sbjct: 22 VRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTREGGAVDTVITNALILDHW 81 Query: 110 GIFDSD 115 GI +D Sbjct: 82 GIVKAD 87
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 31.2 bits (70), Expect = 0.007 Identities = 19/54 (35%), Positives = 27/54 (50%), Gaps = 7/54 (12%) Query: 122 HIHSKGLMHFDIKPNNIMISNRN-EAMLSDFGLSQLVNE------ESRAAPEFG 168 H+ G++H DIKP N++ + E ++ D GL E ES APE G Sbjct: 260 HLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKAPELG 313
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.0 bits (67), Expect = 5e-04 Identities = 9/24 (37%), Positives = 14/24 (58%) Query: 10 GVGIPEVAKACGVSERAVYKWLKN 33 + E+AKA GV+ A+Y K+ Sbjct: 31 STSLGEIAKAAGVTRGAIYWHFKD 54
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 144 bits (364), Expect = 4e-43 Identities = 53/277 (19%), Positives = 115/277 (41%), Gaps = 35/277 (12%) Query: 4 ILFKWVLCLLLGFSSVSYSREFTIDFSTQQSYVSSLNSIRTEISTPLEHISQGTTSVSVI 63 + +L L L +V F + +T SY ++++R + + + ++ Sbjct: 6 VFSLLILTLFLTAPAVEGDVSFRLSGATSSSYGVFISNLRKALPYERK-----LYDIPLL 60 Query: 64 NHTPPGSYFAVDIRGLDVYQARFDHLRLIIEQNNLYVAGFVNTATNTFYRFSDFT----- 118 T PGS I L Y + + + I+ N+YV G+ A +T Y F++ + Sbjct: 61 RSTLPGSQRYALIH-LTNYAD--ETISVAIDVTNVYVMGY--RAGDTSYFFNEASATEAA 115 Query: 119 HISVPGVT-TVSMTTDSSYTTLQRVAALERSGMQISRHSLVSSYLALMEFSGNTMTRDAS 177 V++ +Y LQ A R + + +L S+ L ++ N+ A+ Sbjct: 116 KYVFKDAKRKVTLPYSGNYERLQIAAGKIRENIPLGLPALDSAITTLFYYNANS----AA 171 Query: 178 RAVLRFVTVTAEALRFRQIQREFRQALSETAPVYTMTPGDVDLTLNWGRISNVLPEYRGE 237 A++ + T+EA R++ I+++ + + +T + + + L +W +S + Sbjct: 172 SALMVLIQSTSEAARYKFIEQQIGKRVDKT---FLPSLAIISLENSWSALSKQIQIASTN 228 Query: 238 DGV----------RVGRISFNNISA--ILGTVAVILN 262 +G + R++ N+ A + +A++LN Sbjct: 229 NGQFETPVVLINAQNQRVTITNVDAGVVTSNIALLLN 265
>PF06291#Lambda prophage Bor protein Length = 102 Score = 163 bits (413), Expect = 3e-56 Identities = 89/97 (91%), Positives = 91/97 (93%) Query: 1 MKKMLLATALALLITGCAQQTFTVQNKQTAVAPKETITHHFFVSGIGQKKTVDAAKICGG 60 MKKML + ALA+LITGCAQQTFTV NK TAV PKETITHHFFVSGIGQKKTVDAAKICGG Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65 Query: 61 TENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 97 ENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ Sbjct: 66 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.008 Identities = 17/91 (18%), Positives = 29/91 (31%), Gaps = 25/91 (27%) Query: 179 KILKAEQALDRNIARIESIERSLL----------------TLDVLAETAPKLRADRERIN 222 K ++A L +++E IE +L LD L +T + + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319 Query: 223 AARDKLRAETDILTNQRRGVVTPVSDIVSSL 253 ++ Q + PVS V L Sbjct: 320 KNEERQ---------QASVIRAPVSVKVQQL 341
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 33.1 bits (75), Expect = 0.004 Identities = 21/101 (20%), Positives = 46/101 (45%), Gaps = 10/101 (9%) Query: 613 QEVAAQQQALQQQQAELQMREMAGRVAKLEADAARAHAAAQRDNASAQREVALTQGQRYV 672 +E A ++A Q+ AE + +E+ + +A+ R A+ + +R AL++ + V Sbjct: 141 KEAEAAEKAFQE--AEQRRKEIE----REKAETERQLKLAEAEE---KRLAALSEEAKAV 191 Query: 673 DALNQAHTAEIITGVQNMEQEQDVLQQQMLYTLQQRMNEMS 713 + + + + V M+ E L ++ ++ R EM Sbjct: 192 EIAQKK-LSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMK 231
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 34.7 bits (79), Expect = 0.001 Identities = 30/111 (27%), Positives = 48/111 (43%), Gaps = 4/111 (3%) Query: 130 KNTQATQSKESAAASAKSASDSAK--TATSRAAEAGQKATDATEAATRAVTAAGNAEESS 187 K TQA Q+ + AA+ A A T R + +A + T + T +A ++ Sbjct: 63 KKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAA 122 Query: 188 TRAGESEKAAGADAEKARQHAEKARLAQESAGEILKRAEAATVSAEEARRM 238 +A + EKAR+ AE A A + A + +R E AE R++ Sbjct: 123 MQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQ--RRKEIEREKAETERQL 171
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 113 bits (283), Expect = 2e-33 Identities = 46/167 (27%), Positives = 73/167 (43%), Gaps = 31/167 (18%) Query: 79 SGYEGKDKNPQGINIRYRYEITDD-FGVITSFTWTRSLTNSQTFIDVQSADHTRKIKNPA 137 S +G+ G N++YRYE + GVI SFT+T K+ Sbjct: 35 SDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTE--------------------KSRT 74 Query: 138 ASARTDIRANYWSLLAGPSWRVNQYMSLYAMAGMGVAKVSADLKIKDNINSSGGFSESNS 197 AS+ + Y+ + AGP++R+N + S+Y + G+G K + + + Sbjct: 75 ASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQT----------TEYPTYKHD 124 Query: 198 TKKTSLAWAAGAQFNLNESVTLDVAYEGSGSGDWRTSGVTAGIGLKF 244 T ++ AG QFN E+V LD +YE S AG+G +F Sbjct: 125 TSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVGYRF 171
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 72.7 bits (178), Expect = 3e-17 Identities = 43/176 (24%), Positives = 70/176 (39%), Gaps = 23/176 (13%) Query: 26 TFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQ 85 DP ++ L++ DMQN + +D S + ANI+ G+ +++ Sbjct: 25 VPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQLGIPVVY-- 76 Query: 86 NGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVL 145 PGS N L G L G ++ +++ EL P+ D+VL Sbjct: 77 ---------TAQPGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELAPEDDDLVL 121 Query: 146 PKPRYSGFFNTPLDSILRSRGIRHLVFTSIATNVCVESTLRDGFFLEYFGVVLEDA 201 K RYS F T L ++R G L+ T I ++ T + F + + DA Sbjct: 122 TKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDA 177
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 29.6 bits (66), Expect = 0.025 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 335 DQVIKTVVNIIGKSIRPDDLLA--RVGGEEFGVLLTDIDTERAKALAERIRENVERLTGD 392 D + + N + + P +L+ R G +EFG+ LT + + K E I E+ G Sbjct: 313 DSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNK--IENIDAFKEKWEGK 370 Query: 393 NPEYAIPQKVTISIGAV 409 Y P ++ SIG+V Sbjct: 371 VITY--PNFISTSIGSV 385
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 30.1 bits (67), Expect = 0.004 Identities = 13/40 (32%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 5 YFLFAGIILCAFIAAILSHIAFHHANEPAEQNISCNAHVI 44 Y L + +I+ I A ++ A H N+PAEQ + H + Sbjct: 366 YGLSSALIVAGGIGAGVT-TALHRRNQPAEQTTTTTTHTV 404
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (260), Expect = 6e-29 Identities = 70/255 (27%), Positives = 118/255 (46%), Gaps = 11/255 (4%) Query: 18 LHNKVAIVTGAAGELGRGLCSALAKAGANLLLVDIK-EPDNRYLKHLTHEGVEVEFMTID 76 + K+A +TGAA +G + LA GA++ VD E + + L E E D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 77 ITKPDASCTIINRCLERFGQLDILVNNAGVCNINRPIDFNRNDWDPMINLNLNAAFDMSQ 136 + A I R G +DILVN AGV + +W+ ++N F+ S+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 137 AALNIFVPQRKGKIINMCSVLSFHGGRWSPG-YAATKHALAGLTKAYADDFAEYNIQING 195 + + +R G I+ + S + R S YA++K A TK + AEYNI+ N Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 196 IAPGYYVSEMTAIIYNNPKIKE-LIKGR-------IPAQRWGRAQDLMGAMVFLASAASD 247 ++PG ++M ++ + E +IKG IP ++ + D+ A++FL S + Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 248 YVNGQLLVIDGGYSI 262 ++ L +DGG ++ Sbjct: 245 HITMHNLCVDGGATL 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 677 bits (1748), Expect = 0.0 Identities = 237/805 (29%), Positives = 386/805 (47%), Gaps = 44/805 (5%) Query: 28 ATPSDEDNYTFDPQLFRGSRFSQSSLAKLTTRESVAPGNYKMDIYTNNKLSGSWNVTFKE 87 P F+P+ + + L++ + + PG Y++DIY NN + +VTF Sbjct: 39 QAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNT 98 Query: 88 AADG-RVLPCLTPEVADAIGLKTGEDKGEK---DPVCTFAKELAPGITSQTQLSQLRLDL 143 ++PCLT ++GL T G D C + T+Q + Q RL+L Sbjct: 99 GDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNL 158 Query: 144 SVPQSQLISRPRGYVPPSELDTGASLAFMNYIANYYNVAYSGQNAHSQRSLWASFNGGIN 203 ++PQ+ + +R RGY+PP D G + +NY + + + + + + G+N Sbjct: 159 TIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNS--VQNRIGGNSHYAYLNLQSGLN 216 Query: 204 LGAWQYRQLSNMTW-----DNDKGNQWNNIRSYLQRPLPAINSQLMMGQLITSGRFFSGL 258 +GAW+ R + ++ + N+W +I ++L+R + + S+L +G T G F G+ Sbjct: 217 IGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGI 276 Query: 259 SYHGVSLATDERMLPDSMRGYAPTIRGVAATNARVSVMQNGHEIYQTTVAPGPFEINDLY 318 ++ G LA+D+ MLPDS RG+AP I G+A A+V++ QNG++IY +TV PGPF IND+Y Sbjct: 277 NFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIY 336 Query: 319 PTSYSGDLDVTVTEANGAVSRFSVPFSAVPESMRPGTSRYNVEVGKTQDSG---DDSMFG 375 SGDL VT+ EA+G+ F+VP+S+VP R G +RY++ G+ + + F Sbjct: 337 AAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFF 396 Query: 376 DLTWQHGMTNTLTFNSGSRIADGYQALMLGGVYGS-SLGAFGANLTWSHARVPESEAQSG 434 T HG+ T G+++AD Y+A G +LGA ++T +++ +P+ G Sbjct: 397 QSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDG 456 Query: 435 WMSQLTWSKTFQPTSTTVSLAGYRYSTSGYRDLADVLGERHAASNKQSWD---------- 484 + ++K+ + T + L GYRYSTSGY + AD R N ++ D Sbjct: 457 QSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFT 516 Query: 485 ---SSQWRQQSRFDLTLSQSLANYGNLFVSGSTQNYRGGKSRDTQLQLGYSNSFSHGISM 541 + + ++ + LT++Q L L++SGS Q Y G + D Q Q G + +F I+ Sbjct: 517 DYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF-EDINW 575 Query: 542 NLSVGRQRMGGYKDNSDDMQTVTSLSFSFPLGG-------NGPRVPSLSNSWTHSTDGSS 594 LS + D +L+ + P + R S S S +H +G Sbjct: 576 TLSYSLTKNAW--QKGRDQM--LALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRM 631 Query: 595 QLQSSLTGMLDEAQTTNYSLNV---MRDQQYKQTTLSGNMQKRFSQTTVGLNASKGQDYW 651 + + G L E +YS+ +T + R + S D Sbjct: 632 TNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIK 691 Query: 652 QASGNVQGAMAVHGGGITFGPYLGETFALVEAKGAEGAKVYNSSQLEINDSGYALVPAVT 711 Q V G + H G+T G L +T LV+A GA+ AKV N + + + GYA++P T Sbjct: 692 QLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYAT 751 Query: 712 PYRYNRISLDPQGMDGDAELVDSERQVAPVAGAAVKVIFRTRPGKALLIKSRMADGSELP 771 YR NR++LD + + +L ++ V P GA V+ F+ R G LL+ + LP Sbjct: 752 EYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLP 810 Query: 772 MGADVLDENNTVVGIAGQGGQIYLR 796 GA V E++ GI GQ+YL Sbjct: 811 FGAMVTSESSQSSGIVADNGQVYLS 835
>SECA#SecA protein signature. Length = 901 Score = 28.7 bits (64), Expect = 0.022 Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 14/66 (21%) Query: 170 VTNPTGYYVTIRAAELLNNGKKVPLANSVMIAPQSTTEW-----TLPSGISVAPGAQIHL 224 V + V + +LN IA T E TLP+ ++ G +H+ Sbjct: 78 VFGMRHFDVQLLGGMVLNERC---------IAEMRTGEGKTLTATLPAYLNALTGKGVHV 128 Query: 225 VTVNDY 230 VTVNDY Sbjct: 129 VTVNDY 134
>PF05860#haemagglutination activity domain. Length = 117 Score = 64.8 bits (158), Expect = 2e-14 Identities = 23/126 (18%), Positives = 48/126 (38%), Gaps = 21/126 (16%) Query: 39 KNGTVYNANGVPVVDINKPNGSGLSHNIWDNLNVDKNGVVFNNSANESSTSLAGNIQGNS 98 N + +++ GS L H+ + +V +G F N+ Sbjct: 11 INSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNP--------------- 54 Query: 99 NLTSGSAKVILNEVTSKNPSTINGMMEVAGDKADLIIANPNGITVNGGGSINTGKLTLTT 158 + + I++ VT + S I+G++ A+L + NPNGI ++ G + + Sbjct: 55 ----TNIQNIISRVTGGSVSNIDGLIRANA-TANLFLINPNGIIFGQNARLDIGGSFVGS 109 Query: 159 GTPDIQ 164 ++ Sbjct: 110 TANRLK 115
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 28.1 bits (62), Expect = 0.010 Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 5/61 (8%) Query: 74 VELLPVEITPDEQKEPVAAIAPSLSTSTQTSVSAGSCKVEFRHGNMTLENPSPELLTLLI 133 VE P +PDE P+ P+L T+ + ++L N +LT+ Sbjct: 40 VEGGPTVPSPDEPGLPLPGPGPALPTNGAIPIPEPGTAPA-----VSLMNMDGSVLTMWS 94 Query: 134 R 134 R Sbjct: 95 R 95
>SYCECHAPRONE#Gram-negative bacterial type III secretion SycE chaperone signature. Length = 130 Score = 26.6 bits (58), Expect = 0.033 Identities = 14/34 (41%), Positives = 21/34 (61%), Gaps = 2/34 (5%) Query: 43 LKNQDPTNPMENNELTSQLAQISTVSGIEKLNTT 76 L N+ P N ++NN L +QL + V G E+L T+ Sbjct: 89 LWNRQPLNSLDNNSLYTQLEML--VQGAERLQTS 120
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 4e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 353 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 401 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 37.2 bits (86), Expect = 1e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 349 bits (897), Expect = e-126 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 427 bits (1098), Expect = e-152 Identities = 156/363 (42%), Positives = 213/363 (58%), Gaps = 9/363 (2%) Query: 4 FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63 F + L A RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 64 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAIAQGNLSVTVNRQANVSQPDTPFGG 299 +N+ V T AKVVIN RTG++V+ +V + A++ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 360 AKL 362 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 508 bits (1308), Expect = 0.0 Identities = 311/313 (99%), Positives = 311/313 (99%) Query: 1 MISDSKLLASAAWDAQSLNELKAKASEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKA EDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSEHTRLYTSMYDQQIAQQMTTGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 LFSSEHTRLYTSMYDQQIAQQMT GKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 677 bits (1747), Expect = 0.0 Identities = 541/546 (99%), Positives = 543/546 (99%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNSQHKAGFDANGDEGEDFFAIGKPAVLQNTKNNGNVAIGATVTDASAVLATD 361 ALAFAEAFN+QHKAGFDANGD GEDFFAIGKPAVLQNTKN G+VAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSTTQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSS TQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.8 bits (108), Expect = 1e-07 Identities = 41/226 (18%), Positives = 81/226 (35%), Gaps = 9/226 (3%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDNDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD+D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAGYKTETAPFSEVNGDYVGGTESIKQQVDASRSMVIGHTGDKIFDSITSN 186 T NG + + +G E+I + +G G + + Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232 + T A + + TA DK Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 64.3 bits (156), Expect = 3e-12 Identities = 47/288 (16%), Positives = 84/288 (29%), Gaps = 36/288 (12%) Query: 513 PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAAPVVAPAPKAAPATPATPAQPGLL 571 P E+ + DVP P+ E A AP P APATP+ Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETT----- 1037 Query: 572 SRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSER-- 629 ET + Q QN + + + ++ Sbjct: 1038 ---------------ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 630 TEGSDNREENRRNRRQAQQQTAETREGRQQAEVTEKARTADEQQAPRRERSRRRNDDKRQ 689 E + + E + + ++TA + + TEK + + + + + + Q Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 690 AQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEETVVAPV 744 A+ + +N++E Q + +P + + Q V +V V P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 745 AEETVAAEPIVQEAPA------PRTELVKVPLPVVAQTAPEQQEENNA 786 +P V + R + VP V T A Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 63.5 bits (154), Expect = 4e-12 Identities = 46/261 (17%), Positives = 81/261 (31%), Gaps = 26/261 (9%) Query: 551 VAPAPKAAPATPATPAQPGLLSRFFGALKALFSGGEETKPTEQP-APKAEAKPERQQDRR 609 P + S E + E P P A A P Sbjct: 991 TVDTTNITTPNNIQADVPSVPSN----------NEEIARVDEAPVPPPAPATPSETT--- 1037 Query: 610 KPRQNNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETREGRQQAEV------T 663 N ++++++ D E +NR A++ + + Q EV T Sbjct: 1038 -----ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 664 EKARTADEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQR 723 ++ +T + ++ E+ + + + Q+ K + + QE + + + R Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 724 QLNQKVRYEQSVAEETVVAPVAEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEE 783 +N K Q+ P E + E V E+ T V P A Q Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 784 NNADNRDNGGMPRRSRRSPRH 804 N+ + RRS RS H Sbjct: 1212 NSESSNKPKNRHRRSVRSVPH 1232
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 28.4 bits (63), Expect = 0.045 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 137 GVNGDAVDPKSVTSWADL------WKPEYKGSLLLTDDAREVFQMALRKLGYSGNTTDPK 190 G GD DP T+W D + ++ +L D + FQM + +GN T P Sbjct: 42 GFGGDPCDP--CTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPT 99 Query: 191 EIEAAYN 197 + A N Sbjct: 100 TLTAREN 106
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 25.8 bits (56), Expect = 0.043 Identities = 14/52 (26%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 1 MTDEIPLDDALLQLREF--IDENSGEFFVQVWGNGA-NFDNTILRRSYERQG 49 + I D+ LQL E NS + G + DN + S E +G Sbjct: 171 KKEVISSDN--LQLPELKQKSSNSRKKRSTSAGPTVPDRDNDGIPDSLEVEG 220
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.1 bits (62), Expect = 0.032 Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 13/79 (16%) Query: 42 AELTAAMTAIRETAQIAKL-----------MNEAKTQAEVNAAIGELNSKLASIQRECVS 90 +L A + E +I++ EAK Q V A+ E NSKLA++++ Sbjct: 361 KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQ--VEKALEEANSKLAALEKLNKE 418 Query: 91 LVELVGTYQEINASLKAKI 109 L E ++ A L+AK+ Sbjct: 419 LEESKKLTEKEKAELQAKL 437
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 32.2 bits (73), Expect = 0.001 Identities = 15/58 (25%), Positives = 27/58 (46%), Gaps = 6/58 (10%) Query: 22 GSNVVLPAEEAEELARIALASLAAVSDERAAYELFMEKRFG-----ESVDRRRAKNGD 74 + +PA++ E R+ LA +EL +++FG E V+ +RA G+ Sbjct: 82 SGAIEVPADKVHE-LRLRLAQQGLPKGGAVGFELLDQEKFGISQFSEQVNYQRALEGE 138
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 64.8 bits (158), Expect = 2e-18 Identities = 18/46 (39%), Positives = 32/46 (69%) Query: 23 QKAMLIALIVICITVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 68 + +++ ++++C+T+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 70.8 bits (173), Expect = 2e-18 Identities = 31/78 (39%), Positives = 49/78 (62%) Query: 28 PRQLVKALPQYPAYAAANYIKGRVDVKFDIGADGTVTRIEFIRSEPHHLFDEQVVKAMAK 87 PR L + PQYPA A A I+G+V VKFD+ DG V ++ + ++P ++F+ +V AM + Sbjct: 153 PRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRR 212 Query: 88 WRFEKDRPRKGVKKTFIF 105 WR+E +P G+ +F Sbjct: 213 WRYEPGKPGSGIVVNILF 230
>PF06291#Lambda prophage Bor protein Length = 102 Score = 170 bits (432), Expect = 4e-59 Identities = 91/97 (93%), Positives = 93/97 (95%) Query: 1 MKKMLLATALALLITGCAQQTFTVQNKPAAVTPKETITHHFFVSGIGQKKTVDAAKICGG 60 MKKML + ALA+LITGCAQQTFTV NKP AVTPKETITHHFFVSGIGQKKTVDAAKICGG Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65 Query: 61 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 97 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ Sbjct: 66 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>INTIMIN#Intimin signature. Length = 939 Score = 29.3 bits (65), Expect = 0.019 Identities = 32/202 (15%), Positives = 61/202 (30%), Gaps = 29/202 (14%) Query: 76 DWAATGQGQKSAGDTSFT----LAWMPGEQGQQALLAWFNEGDTRAYKIRFPNGTVDVFR 131 G G+ + S + + AL + A I + Sbjct: 611 SANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSAL-------NANAV-IFVDQTKASITE 662 Query: 132 GWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTAATGMTVTPASTSVVKGQSTTL 191 ++ IT TVKV +P ++ + T ++ + T TL Sbjct: 663 IKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTL 722 Query: 192 T---------------VAFQPEGATDKSFRAVSADKTKATVSVSGMTITVKG--VAAGKV 234 T VA + + F ++ D + +G+ + + G+V Sbjct: 723 TSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQV 782 Query: 235 NIPVVSGNGEFAAVAEINVTAS 256 N+ GNG++ + AS Sbjct: 783 NLKASGGNGKYTWRSANPAIAS 804
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 24.9 bits (54), Expect = 0.037 Identities = 10/39 (25%), Positives = 20/39 (51%) Query: 11 ARLSGFRHKTVKVPEWRNVSVVLREPSAEAWYLWQEVLN 49 ++ S F RN+ ++ RE + AW W++V++ Sbjct: 508 SKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVID 546
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 32.0 bits (72), Expect = 0.015 Identities = 45/240 (18%), Positives = 93/240 (38%), Gaps = 24/240 (10%) Query: 356 RAQQAVAAARGTEMQIAAEARLAATQERLN-------RNIAARSAAQNALNSTTAVGSRL 408 +A+QA A E Q A+A A +RL R+ A+R+ + L + Sbjct: 66 QAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQA 125 Query: 409 MSGALGLVGGVPGLVMLGAAAWYTLYQNQEQARESARQYALTIDEIAHKTPSMSLPEASD 468 L L AA + +++ +E R+ A T ++ + ++ Sbjct: 126 EDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQL----------KLAE 175 Query: 469 NEGRTRAALTEQNRLID-------EQASRVKSLQEKAQSIQDVLAGLEDRRVALIRQQAA 521 E + AAL+E+ + ++ S V + + +++ L+ R A ++ A Sbjct: 176 AEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAG 235 Query: 522 EQNKVYQSMLVMNGQHTEFNRLLGLGNELLQQRQGLVNVPLRLPQATLDDKQQSALTKTE 581 ++N++ Q+ +L N+ LQ R R+ + +++Q +T +E Sbjct: 236 KRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASE 295
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 82.6 bits (204), Expect = 1e-22 Identities = 39/134 (29%), Positives = 67/134 (50%), Gaps = 12/134 (8%) Query: 7 VILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG-SDDLNGINVKYRYEFMDA-LG 64 + + + V A T ++ ST++ GY A ++ G + + G N+KYRYE ++ LG Sbjct: 4 IACLSALAAVLAFTAGTSVAATSTVTGGY--AQSDAQGQMNKMGGFNLKYRYEEDNSPLG 61 Query: 65 LITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRV 124 +I SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Y + Sbjct: 62 VIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKF 113 Query: 125 STFSGDYLRVTDNK 138 T + + Sbjct: 114 QTTEYPTYKHDTSD 127
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 44.7 bits (105), Expect = 2e-06 Identities = 54/319 (16%), Positives = 118/319 (36%) Query: 154 ARAASTSAGQAASSAQSASSSAGTASTKATEASKSAAAAESSKSAAATSAGAAKTSETNA 213 + S S AA A + S+A T+A +A+++ AAAE+ A A + + Sbjct: 39 GKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIV 98 Query: 214 AVSQQSAATSASTATTKASEAASSARDASASKEAAKSSETSAASSASSAASSATAAGNSA 273 + + A+ +AT A ++ + AK+ E + + ++ + A Sbjct: 99 NEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRK 158 Query: 274 KAAKTSETNAKSSETAAEQSASAAAGSKTAAALSASAASTSAGQASASATAAGKSAESAA 333 + + + + A + AA S+ A A+ + SA Q+ ++ Sbjct: 159 EIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSR 218 Query: 334 SSASTATTKAGEATEQASAAASSASAAKTSETNAKASETSAESSKTAAASSASSAASSAS 393 S+S A T + ++AK E + + S ++ A Sbjct: 219 LSSSIHARDAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRV 278 Query: 394 SASASKDEATRQASAAKSSATTASTKATEAAGSATAAAQSKSTAESAATRAETAAKRAED 453 A ++E +Q +A+++ + T+ + + + +++ + AE K+A++ Sbjct: 279 GAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQN 338 Query: 454 IASAVALEDASTTKKGIVQ 472 ++DA Q Sbjct: 339 NLLNSQIKDAVDATVSFYQ 357 Score = 31.6 bits (71), Expect = 0.019 Identities = 58/332 (17%), Positives = 111/332 (33%), Gaps = 22/332 (6%) Query: 315 AGQASASATAAGKSAESAASSA----STATTKAGEATEQASAAASSASAAKTSETNAKAS 370 +G KS SAA A STA K +A + A A A++ + AK + Sbjct: 32 SGSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALT 91 Query: 371 E---------TSAESSKTAAASSASSAASSASSASASKDEATRQASAAKSSATTASTKAT 421 + +S+T +A+ + A ++A A + + A+ A A Sbjct: 92 QRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQ 151 Query: 422 EAAGSATAAAQSKSTAESAATRAETAAKRAEDIASA-----VALEDASTTKKGIVQLSSA 476 EA + K+ E AE KR ++ +A + S + +V++ Sbjct: 152 EAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGE 211 Query: 477 TNSTSESLAATPKAVKAAYELANGKYTAQDATTAQKGIVQLSNATNSTSEMLAATPKSVK 536 + + L+++ A A + GK +A+ + + A P + Sbjct: 212 IKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAK---YKELDELVKKLSPRANDPLQNR 268 Query: 537 AAYDLANGKYTAQDAT-TAQKGIVQLSSATNSASETLAATPKAVKAANDNANGRVPSARK 595 ++ + A QK + + N + + KA+ ++N N + + Sbjct: 269 PFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHE 328 Query: 596 VNGKALSSDITLTPKDIGTLNSTTMSFSGGAG 627 + L I T+SF Sbjct: 329 AEENLKKAQNNLLNSQIKDAVDATVSFYQTLT 360
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 31.4 bits (71), Expect = 0.002 Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 7/66 (10%) Query: 41 TKEHLLPHFL-EHLGNNHLDI------GVGTGFYLTHVPESSLISLMDLNEASLNAASTR 93 T EHL F+ HL + ++I G TGFY++ + S + D A++ Sbjct: 54 TLEHLYAGFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKV 113 Query: 94 AGESKI 99 ++KI Sbjct: 114 ENQNKI 119
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 527 bits (1358), Expect = 0.0 Identities = 313/317 (98%), Positives = 316/317 (99%) Query: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS Sbjct: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 Query: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR Sbjct: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 Query: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI Sbjct: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 Query: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVEASDNDEHYDPGKRIT 240 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVE+SDNDEHYDPGKRIT Sbjct: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT 240 Query: 241 YRSKVKDQNYYSVSVNAGYYVTPNAKVYVEGTWNRVTNKKGNTSLYDHNDNTSDYSKNGA 300 YRSKVKDQNYYSV+VNAGYYVTPNAKVYVEG WNRVTNKKGNTSLYDHN+NTSDYSKNGA Sbjct: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGA 300 Query: 301 GIENYNFITTAGLKYTF 317 GIENYNFITTAGLKYTF Sbjct: 301 GIENYNFITTAGLKYTF 317
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.7 bits (61), Expect = 0.009 Identities = 9/49 (18%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 1 MKEGRRMDKRAKNQIVDSDIARLLLKLRKSRNLTVTELAQRSGVSQAMI 49 ++ ++ + + I+D A L + + ++ E+A+ +GV++ I Sbjct: 2 ARKTKQEAQETRQHILDV--ALRLFSQQGVSSTSLGEIAKAAGVTRGAI 48
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 156 bits (395), Expect = 3e-50 Identities = 157/161 (97%), Positives = 157/161 (97%) Query: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQA 60 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMV PADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQQKRDVKPVESR 120 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQ KRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 121 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQK 161 PASPFENTAPAR TSSTATAATSKPVTSVASGPRALSRNQ Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQP 161
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 29.3 bits (65), Expect = 0.002 Identities = 12/36 (33%), Positives = 21/36 (58%) Query: 17 TSPGGTRHRITKFIVEDAIMETLLPNVNTSEGCFEI 52 T G H++ K + AI E L+ NV++++ FE+ Sbjct: 91 TDSGAMSHKLEKADLLKAIQEQLIANVHSNDDYFEV 126
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 59.5 bits (144), Expect = 3e-16 Identities = 18/46 (39%), Positives = 31/46 (67%) Query: 23 QKAMLIALIVICLIVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 68 + +++ ++++CL +++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>PF07675#Cleaved Adhesin Length = 1358 Score = 28.1 bits (62), Expect = 0.033 Identities = 17/73 (23%), Positives = 30/73 (41%), Gaps = 4/73 (5%) Query: 116 IPANTFAVVLESDSMSTSGGGVSIPNGSTVFVDPDRIVQPGNIVLALPKGTTTPVIRKLE 175 I A+ + V S G GV+ +G +I + GN + + + PVI++++ Sbjct: 267 IQASAGSYVAISKDGVLYGTGVANASGVATVNMTKQITENGNYDVVITRSNYLPVIKQIQ 326 Query: 176 IEGPDILLVPTNP 188 P P P Sbjct: 327 AGEPS----PYQP 335
>INTIMIN#Intimin signature. Length = 939 Score = 32.7 bits (74), Expect = 0.001 Identities = 23/119 (19%), Positives = 45/119 (37%), Gaps = 17/119 (14%) Query: 93 KEVITRTVKVTNVGKPSVAEERSKITPVSAIKVTP-------------TSGTVAKGKTTT 139 ++ IT TVKV KP +E + T + + + TS T K + Sbjct: 675 QDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734 Query: 140 LT--VSFEPESATDKTFRAVSADPSKATI--SVKDMTITVNGVATGKVQIPVVSGNGQF 194 V+ + ++ + F ++ D I + + + G+V + GNG++ Sbjct: 735 RVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKY 793
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.0 bits (67), Expect = 0.043 Identities = 55/235 (23%), Positives = 90/235 (38%), Gaps = 23/235 (9%) Query: 362 AWNDRENARLGLAAATLQSDMEKAGELAARDR--AERDASQLKYTGEAQKAYERLLTPLE 419 ++ ++A++ A + + EL + + L Sbjct: 239 NFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKA 298 Query: 420 KYTARQEELNKALKDGKILRADYNTLMAAAKKDYESTLKKPKSSGVKVSAGERQE----- 474 + + LN + LR D + AKK E+ +K + K+S RQ Sbjct: 299 DLEHQSQVLNANRQS---LRRDLDA-SREAKKQLEAEHQKLEE-QNKISEASRQSLRRDL 353 Query: 475 DQAHAALLALETELRTLEKHSGANEKISQQ-RRDLWKA-ENQYAVLKE-AATKRQLSEQE 531 D + A LE E + LE+ + +E Q RRDL + E + V K +L+ E Sbjct: 354 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALE 413 Query: 532 KF---LLAHKDETLEYKRQLAELGDKVEHQ-KRLNE-LAQQAVRFEEQQSAKQAA 581 K L K T + K AEL K+E + K L E LA+QA + ++ K + Sbjct: 414 KLNKELEESKKLTEKEK---AELQAKLEAEAKALKEKLAKQAEELAKLRAGKASD 465
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 136 bits (344), Expect = 4e-43 Identities = 64/200 (32%), Positives = 101/200 (50%), Gaps = 30/200 (15%) Query: 1 MRKLYAAILSAAICLAVSGAPAWASEHQSTLSAGYLHVSTNVPGSDELNGINVKYRYEFT 60 M+K+ A + + A LA + + A+ ST++ GY + + G N+KYRYE Sbjct: 1 MKKI-ACLSALAAVLAFTAGTSVAA--TSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEED 56 Query: 61 DT-LGMVTSFSYAGDKNRQLTRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGV 119 ++ LG++ SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Sbjct: 57 NSPLGVIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 AYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYE 179 Y + T T+ HD S+ ++GAG+QFNP E+VA+D +YE Sbjct: 109 GYGKFQT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYE 151 Query: 180 GSGSGDWRTDGFIVGVGYKF 199 S +I GVGY+F Sbjct: 152 QSRIRSVDVGTWIAGVGYRF 171
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 114 bits (286), Expect = 4e-29 Identities = 118/467 (25%), Positives = 176/467 (37%), Gaps = 59/467 (12%) Query: 22 NGLMTFNATLGGDNSPTDKMNVKGDTQGNTRVRVDNIGGVGAQTVNGIELIEVGGNSAGN 81 +GL N D +DK+ V D G R+ V N G + N + L++ SA Sbjct: 481 SGLFRMNVFA--DLGLSDKLVVMQDASGQHRLWVRNSGS-EPASANTLLLVQTPLGSAAT 537 Query: 82 FALTT--GTVEAGAYVYTLAKGKGNDEKNWYLTSKWDGVTPADTPDPINNPPVVDPEGPS 139 F L G V+ G Y Y LA N W L P P P PP P Sbjct: 538 FTLANKDGKVDIGTYRYRLAA---NGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPE 594 Query: 140 --VYRPEAGSYIS----------NIAAANSLF---SHRLHDRLGEPQYTDSLHSQDSASS 184 +P AG +S + A++L+ S+ L RLGE L A Sbjct: 595 APAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGE------LRLNPDAGG 648 Query: 185 MWMRHVGGHERSSAGDGQLNTQANRYVLQLGGDLAQWSSNAQDRWHLGVMAGYANQHSNT 244 W R ++ G+ Q +LG D A + A RWHLG +AGY Sbjct: 649 AWGRGFAQRQQLDNRAGRRFDQ-KVAGFELGADHA--VAVAGGRWHLGGLAGYTR----- 700 Query: 245 QSNRVGYKSDGRISGYSAGLYATWYQNDANKTGAYVDSWALYNWFDNSV---SSDNRSAD 301 G+ DG G++ ++ Y +G Y+D+ + +N SD + Sbjct: 701 --GDRGFTGDG--GGHTDSVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVK 756 Query: 302 -DYDSRGVTASVEGGYTFEAGTCSGSEGTLNTWYVQPQAQITWMGVKDSDHARKDGTRIE 360 Y + GV AS+E G F + W+++PQA++ + +G R+ Sbjct: 757 GKYRTHGVGASLEAGRRFTHA---------DGWFLEPQAELAVFRAGGGAYRAANGLRVR 807 Query: 361 TEGDGNVQTRLGVKTYLNSHHQRDDGKQREFQPYIEANWINNSK-VYAVKMNGQTVSRDG 419 EG +V RLG L + + R+ QPYI+A+ + V NG + Sbjct: 808 DEGGSSVLGRLG----LEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIAHRTEL 863 Query: 420 ARNLGEVRTGVEAKVNNNLSLWGNVGVQLGDKGYSDTQGMLGVKYSW 466 E+ G+ A + SL+ + G K G +YSW Sbjct: 864 RGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 939 bits (2429), Expect = 0.0 Identities = 501/869 (57%), Positives = 653/869 (75%), Gaps = 10/869 (1%) Query: 15 QVLLLPRFARLTIALSLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYR 74 + L F RL +A + A AE YFNPRFL++D DLS F G+E PPGTYR Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 75 VDIYLNDEFMTSRDITFITDDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSAEKHVPDN 134 VDIYLN+ +M +RD+TF T D+ ++PCL+ L S+G+ +++ + ++ + Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV-------SGMNLLAD 132 Query: 135 SACTPLQDRLVDASTEFDVGQQHLSLSVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFN 194 AC PL + DA+ + DVGQQ L+L++PQ ++ ARGY+ P+LW+ GINAGLLNY+F+ Sbjct: 133 DACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFS 192 Query: 195 GNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTS 254 GNS N G S+YAYLNLQSG+NIG+WRLRDN+TWSYNS S+S NKWQHINT Sbjct: 193 GNS---VQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTW 249 Query: 255 AERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTA 314 ERDIIPLRSRLT+GD YT GDIFD +NFRG ++ S + MLPDSQ GFAPVIHGIARGTA Sbjct: 250 LERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTA 309 Query: 315 QVSVKQNGYDVYQTTVPPGPFTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQ 374 QV++KQNGYD+Y +TVPPGPFTI+DI +A N GDLQVTIKEADGS Q VPYSSVP+LQ Sbjct: 310 QVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQ 369 Query: 375 RAGYTRYALAMGEYRSGNNLQSSPRFIQGSLMHGLEGNWTPYGGMQIAEDYQAFNLGIGK 434 R G+TRY++ GEYRSGN Q PRF Q +L+HGL WT YGG Q+A+ Y+AFN GIGK Sbjct: 370 REGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGK 429 Query: 435 DLGLFGAFSFDITQANTTLADGTRHSGQSVKSVYSKSFYQTGTNIQVAGYRYSTQGFYNL 494 ++G GA S D+TQAN+TL D ++H GQSV+ +Y+KS ++GTNIQ+ GYRYST G++N Sbjct: 430 NMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNF 489 Query: 495 SDSAYSRMSGYTVKPPTGDSNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGATFFSASR 554 +D+ YSRM+GY ++ G + +F DY+NL Y+KRG+ Q++++QQLG + S S Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 555 QSYWNTSRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTD 614 Q+YW TS D+Q GLN F DI +L+YS + N WQ RD +LA +N+PFSHW+R+D Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSD 609 Query: 615 SQSAFRNSNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYS 674 S+S +R+++ASYSMS+DL G MTNL+GVYGTLL DNNL+YSVQ G GG+ +SG++GY+ Sbjct: 610 SKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYA 669 Query: 675 TLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNV 734 TLNYRG YGN N+GYS S D Q+YYG+SGG++AHA+G+T GQPL DT+VLVKAPGA + Sbjct: 670 TLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDA 729 Query: 735 KIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARAT 794 K+ENQTG+ TDWRGYA+LP+ATEYRENRVAL+ N+LADNV+LD V V+PT GAI RA Sbjct: 730 KVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAE 789 Query: 795 FNAQIGGKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGN 854 F A++G K+LMTL + NK +PFGA+VT +++ IVA+NGQVYL+G+P +GK+QV WG Sbjct: 790 FKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGE 849 Query: 855 DKNSNCIVDYKLPEVSPGTLLNQQTAICR 883 ++N++C+ +Y+LP S LL Q +A CR Sbjct: 850 EENAHCVANYQLPPESQQQLLTQLSAECR 878
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 33.1 bits (75), Expect = 2e-04 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%) Query: 16 LLTATLQAADVTITVNGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 LLT+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPAETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.024 Identities = 7/29 (24%), Positives = 13/29 (44%) Query: 119 WQFDDDKLNTLHHLGAGTFVTSGKRVTAG 147 W+ + + + L +G GT + G G Sbjct: 437 WKVHNPQYDRLAKIGKGTLIVEGTGDNKG 465
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.9 bits (62), Expect = 0.031 Identities = 11/37 (29%), Positives = 18/37 (48%) Query: 29 RRGAIHVISAFSTMHSLVIGQIKTDEKSNEITAIPEL 65 R + ++ SL+IG I DE S ++ +P L Sbjct: 442 SRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLL 478
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 206 bits (525), Expect = 5e-69 Identities = 100/117 (85%), Positives = 107/117 (91%) Query: 1 MKSKVLALLIPALLGAGAAHAAEVYNKDGNKLDLYGKVDGLHYFSDNSAKDGDQSYARLG 60 MK KVLAL+IPALL AGAAHAAE+YNKDGNKLDLYGKVDGLHYFSD+S+KDGDQ+Y R+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGLKFSDYGSFDYGRNYG 117 FKGETQINDQLTGYGQWEYN+QAN TE SWTRLAFAGLKF DYGSFDYGRNYG Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYG 117
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 117 bits (295), Expect = 1e-34 Identities = 81/154 (52%), Positives = 86/154 (55%), Gaps = 59/154 (38%) Query: 45 NDQVNH--TAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDS----DYAVANKT 98 N+QVN T AGGDKADAWTAGLKYDANNIYLATMYSETRNMTP+G + D VANKT Sbjct: 230 NEQVNAGGTIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKT 289 Query: 99 QNFE-----------------------------------------------------STY 105 QNFE STY Sbjct: 290 QNFEVTAQYQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTY 349 Query: 106 VDYKINLLDEDDSFYAANGISTDDIVALGLVYQF 139 VDYKINLLD+DD FY GISTDDIVALG+VYQF Sbjct: 350 VDYKINLLDDDDPFYKDAGISTDDIVALGMVYQF 383 Score = 83.4 bits (206), Expect = 5e-22 Identities = 43/70 (61%), Positives = 50/70 (71%) Query: 2 GWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFFGLVNGLNDQVNHTAAGGDKADAW 61 GWTDMLPEFGGDSYT ADN+MTGRANGVATYRNTDFFGLV+GLN + + ++ Sbjct: 124 GWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQSADD 183 Query: 62 TAGLKYDANN 71 + NN Sbjct: 184 VNIGTNNRNN 193
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 44.9 bits (106), Expect = 7e-10 Identities = 13/35 (37%), Positives = 23/35 (65%) Query: 1 VRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVST 35 +N+++ + AGP+ R+N+W S Y + GV Y + T Sbjct: 81 NKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQT 115
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.045 Identities = 15/103 (14%), Positives = 34/103 (33%), Gaps = 2/103 (1%) Query: 548 YVRSVNLVGKSAFVEASGRASNDAEGYLGLFREKIGKLH--LAQGLWELIDNSQLADEMA 605 Y + +NL K A N E + + ++ L + + ++ Sbjct: 203 YQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYV 262 Query: 606 EMKTSITETRNEITQTVSKTLEDQSAIIQQIQRVQKDTNDDLA 648 E + ++++ Q S+ L + Q + + D L Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR 305
>INTIMIN#Intimin signature. Length = 939 Score = 32.7 bits (74), Expect = 0.001 Identities = 23/119 (19%), Positives = 45/119 (37%), Gaps = 17/119 (14%) Query: 104 KEVITRTVKVTNVGKPSVAEERSKITPVSAIKVTP-------------TSGTVAKGKTTT 150 ++ IT TVKV KP +E + T + + + TS T K + Sbjct: 675 QDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734 Query: 151 LT--VSFEPESATDKTFRAVSADPSKATI--SVKDMTITVNGVATGKVQIPVVSGNGQF 205 V+ + ++ + F ++ D I + + + G+V + GNG++ Sbjct: 735 RVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKY 793
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.030 Identities = 7/43 (16%), Positives = 17/43 (39%) Query: 30 SGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A A++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 342 bits (880), Expect = e-118 Identities = 126/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 6 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 65 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 66 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 125 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 126 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 185 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 186 IMLMAEHFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 245 I + HF Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 246 PLDDIIID---PFKRRPPEDAIAVSETTSLPTLPLD------------------LREFQM 284 + I + P E A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 285 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 325 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 31.6 bits (71), Expect = 0.007 Identities = 33/170 (19%), Positives = 63/170 (37%), Gaps = 34/170 (20%) Query: 101 EALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEENAANADTSAGDASESAR 160 EA + + E A+ E A+K A+ + + E N+ S+ S AR Sbjct: 175 EAEEKRLAALSEEAKAVEIAQKKLSAAQ-----SEVVKMDGEIKTLNSRLSS---SIHAR 226 Query: 161 QAAESAAAAKQSEEASSSSA--------SAAAQKASESLQS----------------ATD 196 A A K++E A +S+ + +A++ LQ+ + Sbjct: 227 DAEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREE 286 Query: 197 AELSKKTAESAAGNAARDATTAAEKARESAESAQSAEQSRIA-AEEAVNR 245 + +E+ N T +KA + ++A +R+ AEE + + Sbjct: 287 KQKQVTASETRI-NRINADITQIQKAISQVSNNRNAGIARVHEAEENLKK 335 Score = 30.8 bits (69), Expect = 0.012 Identities = 35/149 (23%), Positives = 52/149 (34%), Gaps = 10/149 (6%) Query: 101 EALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEENAANADTSAGDASESAR 160 E R+ E+A + AE+ +K E + + ++AEE A + A E Sbjct: 137 EKARKEAEAAEKAFQEAEQRRKEIER-EKAETERQLKLAEAEEKRLAALSEEAKAVE--- 192 Query: 161 QAAESAAAAKQSEEASSSSASAAAQKASESLQSATDAE---LSKKTAESAAGNAARDATT 217 A+ +A QSE S A DAE L+ K E A +A Sbjct: 193 -IAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELD 251 Query: 218 AAEKARESAESAQSAEQSRIAAEEAVNRI 246 K + A Q+R E R+ Sbjct: 252 ELVKK--LSPRANDPLQNRPFFEATRRRV 278
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 137 bits (347), Expect = 1e-43 Identities = 62/195 (31%), Positives = 98/195 (50%), Gaps = 29/195 (14%) Query: 7 VILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG-SDDLNGINVKYRYEFMDA-LG 64 + + + V A T ++ ST++ GY A ++ G + + G N+KYRYE ++ LG Sbjct: 4 IACLSALAAVLAFTAGTSVAATSTVTGGY--AQSDAQGQMNKMGGFNLKYRYEEDNSPLG 61 Query: 65 LITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRV 124 +I SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Y + Sbjct: 62 VIGSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKF 113 Query: 125 STFYGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVTIDLAYEGSGSG 184 T T+ HD S+ ++GAG+QFNP E+V +D +YE S Sbjct: 114 QT--------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYEQSRIR 156 Query: 185 DWRSDAFIVGIGYRF 199 +I G+GYRF Sbjct: 157 SVDVGTWIAGVGYRF 171
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (301), Expect = 3e-39 Identities = 34/89 (38%), Positives = 55/89 (61%) Query: 4 TKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGR 63 K ++ + + L+K+D+ V+ F + L GE+V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPKTGEDIPITARRVVTFRPGQKLKSRVE 92 NP+TGE+I I A +V F+ G+ LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.5 bits (92), Expect = 2e-05 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 1/129 (0%) Query: 29 ALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAATGAAFVPDMY-WLIFFRFLMGTG 87 A M + IG+ G + D G +R ++I + + LI RF+ G G Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 88 MGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPMLSAAIGVVVIAFFSWRIMFLLGG 147 A + +IP RGK + + + AIG ++ + W + L+ Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 148 IGILLAWFL 156 I I+ FL Sbjct: 177 ITIITVPFL 185
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 28.9 bits (64), Expect = 0.024 Identities = 18/81 (22%), Positives = 34/81 (41%), Gaps = 13/81 (16%) Query: 165 ETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKED-----------VLTDGIQTFPDR 213 E ++AL + N D K S S L + F ++V + + V ++ F + Sbjct: 57 EMSAALAQFRNRRDYEKKS-SNLSNSF-ERVLEDEALPKAKQILKLISVHGGALEDFLRQ 114 Query: 214 TDRVYLNPQDCSVINDEALNR 234 ++ +P D ++ E L R Sbjct: 115 ARSLFPDPSDLVLVLRELLRR 135
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.021 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>SECA#SecA protein signature. Length = 901 Score = 60.3 bits (146), Expect = 8e-13 Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 155 RVEKMSPEAFEESVDAIRLAALDLH---AYWMAHPQEKAVQQPI--KAEEKPGRNDPCPC 209 +V+ PE EE R+ A L A E K GRNDPCPC Sbjct: 828 KVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPC 887 Query: 210 GSGKKFKQCC 219 GSGKK+KQC Sbjct: 888 GSGKKYKQCH 897
>PF03944#delta endotoxin Length = 633 Score = 28.1 bits (62), Expect = 0.016 Identities = 11/31 (35%), Positives = 18/31 (58%) Query: 74 TQAYTGRPWPLIDGVGQIYGMYVLTGTNTTR 104 TQ++T + WP + + Q+ YVL G + R Sbjct: 285 TQSFTSQDWPFLYSLFQVNSNYVLNGFSGAR 315
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.018 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 164 RFTLLPIFRIPVKMQKVAAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 218 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 4e-04 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 80 APNYLRRGVASLILRHILQVAHDRCLHRLSLETGTQAGFTACHQLYLKHGFVDC 133 A +Y ++GV + +L ++ A + L LET +ACH Y KH F+ Sbjct: 98 AKDYRKKGVGTALLHKAIEWAKENHFCGLMLET-QDINISACH-FYAKHHFIIG 149
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 27.5 bits (61), Expect = 0.044 Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 5/78 (6%) Query: 1 MFPLNDLSLKTQSVQLNKITSNTESTIKQHELVSDDAIINELSSEKSQGEGTLPIRHKLE 60 M+ + + +S Q N I S H +D +I L S + I H E Sbjct: 1 MYGVIKMEAFIRSDQYNFIKSQAYILANGHATANDRGVIQALKSLAIE-----KIIHVFE 55 Query: 61 FISTNIAELLDKLTKITD 78 ++ EL+D + + + Sbjct: 56 NLTDEQKELIDTVLTVQN 73
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 1e-04 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 20 APNYLRRGVASLILRHILQVAHDRCLHRLSLETGTQAGFTACHQLYLKHGFVDC 73 A +Y ++GV + +L ++ A + L LET +ACH Y KH F+ Sbjct: 98 AKDYRKKGVGTALLHKAIEWAKENHFCGLMLET-QDINISACH-FYAKHHFIIG 149
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 117 bits (294), Expect = 5e-38 Identities = 103/103 (100%), Positives = 103/103 (100%) Query: 2 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 61 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 752 bits (1943), Expect = 0.0 Identities = 478/555 (86%), Positives = 515/555 (92%), Gaps = 5/555 (0%) Query: 3 ATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGA 62 +TA Q K LEWLNRLRANP+IPLIVAGSAAVA++VA++LWAK PDYRTLFSNLSDQDGGA Sbjct: 5 STATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGA 64 Query: 63 IVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 122 IV+QLTQMNIPYRF+ SGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ Sbjct: 65 IVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 124 Query: 123 FSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRA 182 FSEQVNYQRALEGEL+RTIET+GPVK ARVHLAMPKPSLFVREQKSPSASVTV L PGRA Sbjct: 125 FSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRA 184 Query: 183 LDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSWRDLNDAQLKYASDVEGRI 242 LDEGQISA+VHLVSSAVAGLPPGNVTLVDQ GHLLTQSNTS RDLNDAQLK+A+DVE RI Sbjct: 185 LDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRI 244 Query: 243 QRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESQAALRSRQLNESEQSG 302 QRRIEAILSPIVGNGN+HAQVTAQLDFA+KEQTEE Y PNGD S+A LRSRQLN SEQ G Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 303 SGYPGGVPGALSNQPAPANNAPISTPPANQNNRQQ--QASTTSNS---GPRSTQRNETSN 357 +GYPGGVPGALSNQPAP N API+TPP NQ N Q Q ST++NS GPRSTQRNETSN Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSN 364 Query: 358 YEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQMKQIEDLTREAMGFSEK 417 YEVDRTIRHTKMNVGD++RLSVAVVVNYKTL DGKPLPL+ +QMKQIEDLTREAMGFS+K Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK 424 Query: 418 RGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLT 477 RGD+LNVVNSPF++ D +GGELPFWQQQ+FIDQLLAAGRWLLVL+VAW+LWRKAVRPQLT Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 478 RRAEAMKAVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 537 RR E KA Q+QAQ R+E E+AVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR Sbjct: 485 RRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 544 Query: 538 VVALVIRQWINNDHE 552 VVALVIRQW++NDHE Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 262 bits (672), Expect = 3e-89 Identities = 105/328 (32%), Positives = 168/328 (51%), Gaps = 58/328 (17%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTASGIETLN------- 53 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + E + Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 54 -----------------------FMEPQSAADLI-------------------------- 64 + Q A D+I Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNF 131 Query: 65 -RDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLNG 123 + EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 132 IQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEK 191 Query: 124 LLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENLV 182 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++V Sbjct: 192 KLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIV 251 Query: 183 DVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLSQ 242 +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 252 LLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKD 311 Query: 243 VENEQKAILLIVRRLAETGEMVIGSGED 270 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 312 VEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 374 bits (961), Expect = e-135 Identities = 226/228 (99%), Positives = 227/228 (99%) Query: 1 MSDNLPWKTWTPDDLAPPQAEFVPMVESEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 MSDNLPWKTWTPDDLAPPQAEFVP+VE EETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 202 bits (515), Expect = 2e-70 Identities = 146/147 (99%), Positives = 147/147 (100%) Query: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 MTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 +TSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147 AALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 409 bits (1051), Expect = e-145 Identities = 329/334 (98%), Positives = 329/334 (98%) Query: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDVPSTVLPAEKPTLFTKLTSAQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTD PSTVLP EKPTLFTKLTS QLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPQVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTP VAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSSHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVS HQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ 334 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ 334
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 253 bits (648), Expect = 1e-85 Identities = 68/324 (20%), Positives = 119/324 (36%), Gaps = 68/324 (20%) Query: 5 ILSQAEIDALLNGDS--EVKDEPTASVSGES----------------------------- 33 +LSQ EID LL S + E +S Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 34 ----------------------DIRPYD------PN-TQRNLIHLKPLRGTGLVVFSPSL 64 D Y+ P + +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 65 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 124 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 125 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 182 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 183 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLKPGDVLPIEKP---DRIIAHVD 239 + + L ++ +++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 240 GVPVLTSQYGTLNGQYALRIEHLI 263 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 212 bits (542), Expect = 1e-74 Identities = 125/137 (91%), Positives = 134/137 (97%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGGGDVSGTLQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T++KSAADAVFQQ GGGDVSG +QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 334 bits (858), Expect = e-119 Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 203 bits (518), Expect = 3e-67 Identities = 260/261 (99%), Positives = 261/261 (100%) Query: 1 MLQVTSEQWLSWLSLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 MLQVTSEQWLSWL+LYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEIFNLLADIISELPLI 261 EHLFSEIFNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.045 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 15/62 (24%) Query: 320 AKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRG 379 A+Y + PVLW Y+ R+ K + G+ VY +R +DG+E RG Sbjct: 166 ARYQVGPVLWGYVVRFIK---SDGDKLTLPYVY------------SRSQRDGSEAWKWRG 210 Query: 380 WD 381 WD Sbjct: 211 WD 212
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.8 bits (80), Expect = 2e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 37 AQKLAADDDVDMLVILTACYFHDIVSLAKNHPQRQSSSILAAEETRRLLREEFVQFPA-- 94 +KLA + + D+ +ILT + +L + Q + EE R+ E F A Sbjct: 219 GEKLAEEVNADIFMILTDV---NGAALYYGTEKEQWLREVKVEELRKYYEEG--HFKAGS 273 Query: 95 --EKIEAVCHAIAAHSFSAQIAPLTTEAKIVQ 124 K+ A I A IA L + ++ Sbjct: 274 MGPKVLAAIRFIEWGGERAIIAHLEKAVEALE 305
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 307 bits (789), Expect = e-107 Identities = 143/204 (70%), Positives = 160/204 (78%), Gaps = 2/204 (0%) Query: 11 MKRKVLAMLVPALLVAGAANAAEIYNKDGNKLDLYGKVAGLHYFSDDASSDGDMSYARIG 70 MKRKVLA+++PALL AGAA+AAEIYNKDGNKLDLYGKV GLHYFSDD+S DGD +Y R+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 71 FKGETQIADQFTGYGQWEFNIGANGPESDKGNTATRLAFAGFGFGQNGTFDYGRNYGVVY 130 FKGETQI DQ TGYGQWE+N+ AN E + N+ TRLAFAG FG G+FDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 131 DVEAWTDMLPEFGGDTYAGADNFMNGRANSVATYRNNGFFGQVDGLNFALQYQGNNEKSG 190 DVE WTDMLPEFGGD+Y ADN+M GRAN VATYRN FFG VDGLNFALQYQG NE Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 191 LFDQEGSGNG--NGRKLAKENGDG 212 D N NG + +NGDG Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDG 204
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 143 bits (363), Expect = 8e-45 Identities = 85/187 (45%), Positives = 100/187 (53%), Gaps = 64/187 (34%) Query: 1 MSTSYDFDFGLSLGAAYSNSDRTDNQVHKGTHNTRYGDRFDATAGGETAEAWTVGAKYDA 60 +ST+YD G S GAAY+ SDRT+ QV+ G AGG+ A+AWT G KYDA Sbjct: 207 ISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTI----------AGGDKADAWTAGLKYDA 256 Query: 61 NNVYLAAMYAEPRNMTGYGDADA-----IANKTQNFEVVAQYQFDFG------------- 102 NN+YLA MY+E RNMT YG D +ANKTQNFEV AQYQFDFG Sbjct: 257 NNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQFDFGLRPAVSFLMSKGK 316 Query: 103 ------------------------------------KINLLDNDDDFYKENGIATDDIVA 126 KINLLD+DD FYK+ GI+TDDIVA Sbjct: 317 DLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDDDPFYKDAGISTDDIVA 376 Query: 127 VGLVYQF 133 +G+VYQF Sbjct: 377 LGMVYQF 383
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.005 Identities = 35/181 (19%), Positives = 61/181 (33%), Gaps = 37/181 (20%) Query: 290 ENILFLARADKNNVLVKLDSLS----------------LNKEVENLLDYL--EYLSDEKE 331 NI L D L SLS L E+ + YL + E Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239 Query: 332 ICFKVECNQQIFADKI---LLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNSYLNIDIAS 388 + F+ + N I ++ L+Q ++ N I + I P+ +I + D N + +++ + Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD-NGTVTLEVEN 298 Query: 389 PGAKINEPEKLFRRFWRGDNSRHSVGQGLGLSLVKA-IAELHGGSATYHYLNKHNVFRIT 447 G+ + K G GL V+ + L+G A K Sbjct: 299 TGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344 Query: 448 L 448 + Sbjct: 345 V 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 2e-20 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 2 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 61 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 117 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.014 Identities = 31/118 (26%), Positives = 50/118 (42%), Gaps = 10/118 (8%) Query: 132 SARNAGISASQAEESAANADTSAGDASESARQAAESAAAAKQSEEASSSSASAAAQKASE 191 S G S++E SAA T+ ++ + AE AA AK A+A AQ ++ Sbjct: 34 SGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAK---------AAAEAQAKAK 84 Query: 192 SSQSAADAELSKKTAESAAGNAARDATTATEKARESAESAQSAEQSRIA-AEEAVNRI 248 +++ A L E+ NA+R + +A E+ R+A AEE + Sbjct: 85 ANRDALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKE 142 Score = 30.0 bits (67), Expect = 0.020 Identities = 31/147 (21%), Positives = 51/147 (34%), Gaps = 6/147 (4%) Query: 103 EALRRFELMVEEAARHAEEAKKNAGEAETSARNAGISASQAEESAANADTSAGDASESAR 162 E R+ E+A + AE+ +K E + + ++AEE A + A E Sbjct: 137 EKARKEAEAAEKAFQEAEQRRKEIER-EKAETERQLKLAEAEEKRLAALSEEAKAVE--- 192 Query: 163 QAAESAAAAKQSEEASSSSASAAAQKASESSQSAADAELSKKTAESAAGNAARDATTATE 222 A+ +A QSE SS A DAE+ + A + Sbjct: 193 -IAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYKELD 251 Query: 223 KARES-AESAQSAEQSRIAAEEAVNRI 248 + + + A Q+R E R+ Sbjct: 252 ELVKKLSPRANDPLQNRPFFEATRRRV 278 Score = 29.3 bits (65), Expect = 0.039 Identities = 28/162 (17%), Positives = 58/162 (35%), Gaps = 18/162 (11%) Query: 103 EALRRFELMVEEAARHAEEAKKNAGEA---------ETSARNAGISAS----QAEESA-A 148 EA + + E A+ E A+K A E N+ +S+S AE A Sbjct: 175 EAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLA 234 Query: 149 NADTSAGDASESARQ--AAESAAAAKQSEEASSSSASAAAQKASESSQSAADAELSKKTA 206 AS ++ + + ++ + A ++ + + + + + Sbjct: 235 GKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTAS 294 Query: 207 ESAAGNAARDATTATEKARESAESAQSAEQSRIA-AEEAVNR 247 E+ N T +KA + ++A +R+ AEE + + Sbjct: 295 ETRI-NRINADITQIQKAISQVSNNRNAGIARVHEAEENLKK 335
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 34.3 bits (78), Expect = 0.002 Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 4/101 (3%) Query: 532 DLWKAESQYAVL-KEAATKRQLSEQEKSLLAHKDETLEYKRQLAELG---DKVEYQKRLN 587 +++KA ++Y +L K T Q+ EK +++ KD ++ LG + Y K N Sbjct: 205 EIFKASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSENKRTGALGNLKNSYSYNKDNN 264 Query: 588 ELAQQAVRFEEQQSAKQAAISAKARGLTDRQAQRESEAQRL 628 EL+ A ++ +S K L+D ++ S + L Sbjct: 265 ELSHFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEAL 305
>INTIMIN#Intimin signature. Length = 939 Score = 30.8 bits (69), Expect = 0.006 Identities = 23/119 (19%), Positives = 44/119 (36%), Gaps = 17/119 (14%) Query: 134 KEVITRTVKVTNVGKPSVAEERSEITPATAIKVTP-------------TSGTVAKGKTTT 180 ++ IT TVKV KP +E + T + + TS T K + Sbjct: 675 QDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSA 734 Query: 181 LT--VSFEPESATDKTFRAVSADPSKATI--SVKDMTITVNGVATGKVQIPVVSGNGQF 235 V+ + ++ + F ++ D I + + + G+V + GNG++ Sbjct: 735 RVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKY 793
>INTIMIN#Intimin signature. Length = 939 Score = 702 bits (1813), Expect = 0.0 Identities = 221/790 (27%), Positives = 353/790 (44%), Gaps = 70/790 (8%) Query: 139 QQIASTSQQIGSLLAEDMNSEQAANMARGWASSQASGAMTDWLSRFGTARITLGVDEDFS 198 QQ AS Q+ S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224 Query: 199 LKNSQFDFLHPWYETPDNLFFSQHTLHRTDERTQINNGLGWRHFTPTWMSGINFFFDHDL 258 S DFL P+Y++ L F Q D R N G G R F P M G N F D D Sbjct: 225 --GSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDF 282 Query: 259 SRYHSRAGIGAEYWRDYLKLSSNGYLRLTNWRSAPELDNDYEARPANGWDVRAEGWLPAW 318 S ++R GIG EYWRDY K S NGY R++ W + DY+ RPANG+D+R G+LP++ Sbjct: 283 SGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRFNGYLPSY 341 Query: 319 PHLGGKLVYEQYYGDEVALFDKDDRQSNPHAITAGLNYTPFPLMTFSAEQRQGKQGENDT 378 P LG KL+YEQYYGD VALF+ D QSNP A T G+NYTP PL+T + R G END Sbjct: 342 PALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDL 401 Query: 379 RFAVDFTWQPGSAMQKQLDPNEVDARRSLAGSRFDLVDRNNNIVLEYRKKELVRLTLTDP 438 +++ F +Q +Q++P V+ R+L+GSR+DLV RNNNI+LEY+K++++ L + Sbjct: 402 LYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHD 461 Query: 439 VTGKSGEVKSLVSSLQTKYALKGYNVEATALEAAGGKVVTTG----KDILVTLPAYRFTS 494 + G + + +++KY L + +AL + GG++ +G +D LPAY Sbjct: 462 INGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAY---- 517 Query: 495 TPETDNTWPIEVTAEDVKGNFSNREQ-SMVVVQAPTLSQKDSSVSLSSQTLSADSHSTAT 553 N + + A D GN SN ++ V+ + + ++ SA + T Sbjct: 518 VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 554 LTFIAH------DAAGNPVIGLVLSTRHEGVQDITLSDWKDNGDGSYTQILTTGAMSGTL 607 +T+ A A PV ++S G ++ + NG G T L + + Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSANTNGSGKATVTLKSDKPGQVV 633 Query: 608 TLMPQLNGVDAAKAPAVVNIISVSSSRTHSSIKIDKDRYLSGNPIEVTVELR-DENDKPV 666 A A AV I + + + IK DK ++ +T ++ + DKPV Sbjct: 634 VSAKTAEMTSALNANAV--IFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPV 691 Query: 667 KEQKQQLNTAVSIDNVKPGVTTDWKETADGVYKATYTAYTKGSGL-TAKLLMQNWNEDLH 725 Q+ T + K +T+ K +G K T T+ T G L +A++ + Sbjct: 692 SNQEVTFTTTLG----KLSNSTE-KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAP 746 Query: 726 TAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNPINDHTVTFAVLSGS 785 F I + G L + + ++ Sbjct: 747 EVEFFTTLTIDDGNIEIVGTGVKGKLPTV---------------------WLQYGQVNLK 785 Query: 786 ATSFNNQNTAKTDVNGLATFDLKSSK---QEDNTVEVTLENGVKQTLIVSFVGDSSTAQV 842 A+ N + T ++ +A+ D S + +E T +++ + QT ++ + + + Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQT--ATYTIATPNSLI 843 Query: 843 DLQKSKNEVVADGNDSATMTATVRDAKGNLLNDVKVTF----------NVNSAAAKLSQT 892 SK D ++ + N L +V + + + + + QT Sbjct: 844 VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQT 903 Query: 893 EVNSHDGIAT 902 ++ G+A+ Sbjct: 904 AQDAKSGVAS 913 Score = 155 bits (393), Expect = 5e-40 Identities = 96/389 (24%), Positives = 157/389 (40%), Gaps = 44/389 (11%) Query: 1117 TAEAILLNGNRD-----TKIVNIAPDASNAQVTLNIPAQQV--VTNNSDSVQLTATVK-- 1167 TA A NGN T V + + A + + ++++ TATVK Sbjct: 528 TARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKN 587 Query: 1168 --DPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQANGEAHVTLKGKKAGTHTVTA-T 1224 +N PV+ V+ T ++AN A T +G+A VTLK K G V+A T Sbjct: 588 GVAQANVPVSFNIVSGT--AVLSAN-------SANTNGSGKATVTLKSDKPGQVVVSAKT 638 Query: 1225 LGNNNASDAQPVTFVADKDSAVVVLQTSKAEIIGNGVDETTLTATVKDPFDNAVKDLQVT 1284 +A +A V FV +++ ++ K + NG D T T V D V + +VT Sbjct: 639 AEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVT 697 Query: 1285 FSTNPADTQLSQSKSNTNDSGVAEVTFKGTVLGVHTAEATLPNGNNDTKIVNIAPDASNA 1344 F+T +LS S T+ +G A+VT T G A + + D K + Sbjct: 698 FTTTLG--KLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVE---FFT 752 Query: 1345 QVTLNIPAQQVVTNNSDSVQLTATVK-DPSNHPVAGITVNFTMPQDVAANFTLENNGIAI 1403 +T++ ++V T ++ N +G +T + N IA Sbjct: 753 TLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYT--------WRSANPAIAS 804 Query: 1404 TQANGEAHVTLKGKKAGTHTVTATLSNNNTSDSQPVTFVADKTSALVVLQISKNEITGNG 1463 A+ VTLK K GT T++ +SD+Q T+ ++L+V +SK + Sbjct: 805 VDAS-SGQVTLKEK--GTTTISVI-----SSDNQTATYTIATPNSLIVPNMSKRVTYNDA 856 Query: 1464 VDSATLTATVKDQFDNEVNNLPVTFSTAS 1492 V++ NE+ N+ + A+ Sbjct: 857 VNTCKNFGGKLPSSQNELENVFKAWGAAN 885 Score = 129 bits (325), Expect = 7e-32 Identities = 83/397 (20%), Positives = 151/397 (38%), Gaps = 36/397 (9%) Query: 914 TVTASVSSGSQANQQVIFIGDQSTAALTLSVPSGDITVT-------NTAPLHMTATLQDK 966 T A +G+ +N ++ I S + V D T T + TAT++ K Sbjct: 528 TARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVK-K 586 Query: 967 NGNPLKDKEITFSVPNDVASRFSISNSGKGMTDSNGTAIASLTGTLAGTHMITARLANSN 1026 NG + ++F++ + A + S + T+ +G A +L G +++A+ A Sbjct: 587 NGVAQANVPVSFNIVSGTAVLSANSAN----TNGSGKATVTLKSDKPGQVVVSAKTAEMT 642 Query: 1027 VS-DTQPMTFVADKDRAVVVLQTSKAEIIGNGVDETTLTATVKDPFDNVVKNLSVVFRTS 1085 + + + FV ++ ++ K + NG D T T V D V N V F T+ Sbjct: 643 SALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVTFTTT 701 Query: 1086 PADTQLSLNARNTNENGIAEVTLKGTVLGVHTAEAILLNGNRDTKIVNIAPDASNAQVTL 1145 +LS + T+ NG A+VTL T G A + + D K + +T+ Sbjct: 702 LG--KLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVE---FFTTLTI 756 Query: 1146 NIPAQQVVTNNSDSVQLTATVK-DPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQAN 1204 + ++V T ++ N +G +T + N IA A+ Sbjct: 757 DDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYT--------WRSANPAIASVDAS 808 Query: 1205 GEAHVTLKGKKAGTHTVTATLGNNNASDAQPVTFVADKDSAVVVLQTSKAEIIGNGVDET 1264 VTLK K GT T++ +SD Q T+ ++++V SK + V+ Sbjct: 809 -SGQVTLKEK--GTTTISVI-----SSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTC 860 Query: 1265 TLTATVKDPFDNAVKDLQVTFSTNPADTQLSQSKSNT 1301 N ++++ + S++ Sbjct: 861 KNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTII 897 Score = 120 bits (301), Expect = 5e-29 Identities = 80/367 (21%), Positives = 145/367 (39%), Gaps = 29/367 (7%) Query: 821 LENGVKQTLIVSFVGDSSTAQ--VDLQKSKNEVVADGNDSATMTATVRDAKGNLLNDVKV 878 N V T+ V G D K ADG ++ T TATV+ N V V Sbjct: 538 SSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQAN-VPV 596 Query: 879 TFNVNSAAAKLSQTEVNSH-DGIATATLTSLKNGDYTVTASVSSGSQA-NQQVIFIGDQS 936 +FN+ S A LS N++ G AT TL S K G V+A + + A N + DQ+ Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQT 656 Query: 937 TAALTLSVPSGDITVTNTAPLHMTATLQ-DKNGNPLKDKEITFSVPNDVASRFSISNSGK 995 A++T + + T +T T++ K P+ ++E+TF+ + ++ Sbjct: 657 KASIT-EIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFT------TTLGKLSNST 709 Query: 996 GMTDSNGTAIASLTGTLAGTHMITARLANSNVSDTQPMTFVADKDRAVVVLQTSKAEIIG 1055 TD+NG A +LT T G +++AR+++ V P + + + EI+G Sbjct: 710 EKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV----EFFTTLTIDDGNIEIVG 765 Query: 1056 NGVDETTLTATVK-DPFDNVVKNLSVVFRTSPADTQLSLNARNTNENGIAEVTLKGTVLG 1114 GV T ++ + + + A+ ++ ++ +VTLK G Sbjct: 766 TGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASS-----GQVTLKEK--G 818 Query: 1115 VHTAEAILLNGNRDTKIVNIAPDASNAQVTLNIPAQQVVTNNSDSVQLTATVKDPSNHPV 1174 T I + D + N+ + N+ + + ++ + S + + Sbjct: 819 TTTISVI----SSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNEL 874 Query: 1175 AGITVNF 1181 + + Sbjct: 875 ENVFKAW 881 Score = 85.1 bits (210), Expect = 2e-18 Identities = 80/380 (21%), Positives = 130/380 (34%), Gaps = 41/380 (10%) Query: 1415 KGKKAGTHTVTAT-LSNNNTSDSQPVT-FVADKTSALVVLQISKNEITGNGVDSATLTAT 1472 G + +T T LSN D VT F ADKTSA +G ++ T TAT Sbjct: 535 NGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAK-----------ADGTEAITYTAT 583 Query: 1473 VKDQFDNEVNNLPVTFSTASSGLTLTPGESNTNESGIAQATLAGVAFGEQTVTASLANNG 1532 VK + N PV+F+ S L+ +NTN SG A TL G+ V+A A Sbjct: 584 VKKNGVAQANV-PVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMT 642 Query: 1533 ASDNKTVHFIGDTAAAKIIELTPVPDSIIAGTPQNSSGSVITATV-VDNNGFPVKGVTVN 1591 ++ N D A I E+ + +A IT TV V PV V Sbjct: 643 SALNANAVIFVDQTKASITEIKADKTTAVANGQ-----DAITYTVKVMKGDKPVSNQEVT 697 Query: 1592 FTSNAAT---AEMTNGGQAVTNDTVSAGDTTNLYIEVK-DNYGNGVPQQEVTLSVSPSEG 1647 FT+ + T+++ + + + V EV + + Sbjct: 698 FTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLT-- 755 Query: 1648 VTPSNNAIYTTNHDGNF-YASFADTEGNAIANSEVTFTLPEDVRANFTLGDGGKVVTDTE 1706 + N I T G + N A+ + + + + D Sbjct: 756 IDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASG-------GNGKYTWRSANPAIASVDAS 808 Query: 1707 GKAKVTLKGTKAGAHTVTASMAGGKSEQLVVNFIADTLTAQVNLNVTEDNFIANNVGMTR 1766 +VTLK G T++ + ++ + T + + N+++ + V + Sbjct: 809 -SGQVTLKEK--GTTTISVISSDNQT----ATYTIATPNSLIVPNMSKRVTYNDAVNTCK 861 Query: 1767 LQATVTDGNGNPLANEAVTF 1786 + N L N + Sbjct: 862 NFGGKLPSSQNELENVFKAW 881 Score = 76.3 bits (187), Expect = 1e-15 Identities = 91/469 (19%), Positives = 174/469 (37%), Gaps = 44/469 (9%) Query: 2094 SGGKVRTNSSGQA--------PVVLTSNKVGTYTVTASFHNGVT----IQTQTIVKVTGN 2141 GG+++ + S A V + V T A NG + + T T++ Sbjct: 495 QGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQV 554 Query: 2142 SSTAHVASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGLTVYFALKSGSATLTSLTAV 2201 V F AD ++ A ++ T ATV+ +G + V F + SG+A L++ +A Sbjct: 555 VDQVGVTDFTADKTSAKADGTEAITYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 2202 TDQNGIATTSVRGAITGSVTVSAVTTAGGMQTVDITLVAGPAD--ASQSVLKNNRSSLKG 2259 T+ +G AT +++ G V VSA TA ++ V AS + +K ++++ Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSA-KTAEMTSALNANAVIFVDQTKASITEIKADKTTAVA 672 Query: 2260 DFTDSAELHLVLHDISGNPIKVSEGLEFVQSGTNAPYVQVSAIDYSKNFSGEYKATVTGG 2319 + D + + + G+ ++ + F + +S + +G K T+T Sbjct: 673 NGQD--AITYTVKVMKGDKPVSNQEVTFTTTLGK-----LSNSTEKTDTNGYAKVTLTST 725 Query: 2320 GEGIATLIPVLNGVHQAGLSTTIQFTRAEDKIMSGTVLVNGANLPTTTFPSQGFTGAYYQ 2379 G + + ++ V + ++F I G + + G + P+ Sbjct: 726 TPGKSLVSARVSDVAVDVKAPEVEF-FTTLTIDDGNIEIVGTGV-KGKLPTVWLQYGQVN 783 Query: 2380 LNNDNFAPGKTAADYEFSSSASWVDVDATGKVTFKNVGSKWERITATPKTGGPSYIYEIR 2439 L + G + ++ A ++G+VT K G+ I+ + Y I Sbjct: 784 L---KASGGNGKYTWRSANPAIASVDASSGQVTLKEKGT--TTISVISSDNQTA-TYTIA 837 Query: 2440 VKSWWVNAG-DAFMIYSLAENFCSSNGYTLPLGDHLNHSRSRGIGSLYSEWGDMGHYTTE 2498 + + + Y+ A N C + G LP + + +++ WG Y Sbjct: 838 TPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNE-------LENVFKAWGAANKYEYY 890 Query: 2499 AGFHSNMYW---SSSPANSNEQYVVSLATGDQSVFEKLGF--AYATCYK 2542 + + W ++ A S L + K AYATC K Sbjct: 891 KSSQTIISWVQQTAQDAKSGVASTYDLVKQNPLNNIKASESNAYATCVK 939 Score = 59.7 bits (144), Expect = 2e-10 Identities = 49/199 (24%), Positives = 82/199 (41%), Gaps = 5/199 (2%) Query: 1748 VNLNVTEDNFIANNVGMTRLQATVTDGNGNPLANEAVTFTLPADVSASFTLGQGGSAITD 1807 + + + A+ ATV NG AN V+F + VS + L SA T+ Sbjct: 561 TDFTADKTSAKADGTEAITYTATVKK-NGVAQANVPVSFNI---VSGTAVLSAN-SANTN 615 Query: 1808 INGKAEVTLSGTKSGTYPVTVSVNNYGVSDTKQVTLIADAGTAKLASLTSVYSFVVSTTE 1867 +GKA VTL K G V+ + + D A + + + + V+ + Sbjct: 616 GSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQ 675 Query: 1868 GATMTASVTDANGNPVEGIKVNFRGTSVTLSSTSVETDDRGFAEILVTSTEVGLKTVSAS 1927 A PV +V F T LS+++ +TD G+A++ +TST G VSA Sbjct: 676 DAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSAR 735 Query: 1928 LADKPTEVISRLLNAKADI 1946 ++D +V + + + Sbjct: 736 VSDVAVDVKAPEVEFFTTL 754 Score = 57.8 bits (139), Expect = 6e-10 Identities = 51/197 (25%), Positives = 76/197 (38%), Gaps = 12/197 (6%) Query: 2029 LANGSSYEKDLVVIDQKLTLSASSPLIGVNSPTGATLTATLTSANGTPVEGQVINFSVTP 2088 L+NG ++ V SA + + T TAT+ NG ++F++ Sbjct: 549 LSNGQVVDQVGVTDFTADKTSAKA-----DGTEAITYTATVKK-NGVAQANVPVSFNIVS 602 Query: 2089 EGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTASFHNGV-TIQTQTIVKVTGNSSTAHV 2147 A LS TN SG+A V L S+K G V+A + ++ V + + A + Sbjct: 603 GTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV--DQTKASI 660 Query: 2148 ASFIADPSTIAATNSDLSTLKATVEDGSGNLIEGLTVYFALKSGSATLTSLTAVTDQNGI 2207 AD +T A D T V G + V F G + + T TD NG Sbjct: 661 TEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQEVTFTTTLGKLSNS--TEKTDTNGY 717 Query: 2208 ATTSVRGAITGSVTVSA 2224 A ++ G VSA Sbjct: 718 AKVTLTSTTPGKSLVSA 734 Score = 46.2 bits (109), Expect = 2e-06 Identities = 53/287 (18%), Positives = 90/287 (31%), Gaps = 36/287 (12%) Query: 1563 GTPQNSSGSVITATVVDNNGFPVKGVTVNFTSNAATA------EMTNGG----QAVTNDT 1612 + + ++ V NG V V+F + TA TNG + +D Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDK 628 Query: 1613 ----VSAGDTTNLYIEVKDNYGNGVPQQEVTLS-VSPSEGVTPSNNAIYTTNHDGNFYAS 1667 V + T + + N V Q + +++ + + +N T Y Sbjct: 629 PGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAIT------YTV 682 Query: 1668 FADTEGNAIANSEVTFTLPEDVRANFTLGDGGKVVTDTEGKAKVTLKGTKAGAHTVTASM 1727 ++N EVTFT TDT G AKVTL T G V+A + Sbjct: 683 KVMKGDKPVSNQEVTFT------TTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARV 736 Query: 1728 AGGKSE--QLVVNFIADTLTAQVNLNVTEDNFIANNVGMTRLQATVTDGNGN-PLANEAV 1784 + + V F N+ + + V + G N + Sbjct: 737 SDVAVDVKAPEVEFFTTLTIDDGNIEI-----VGTGVKGKLPTVWLQYGQVNLKASGGNG 791 Query: 1785 TFTLPADVSASFTLGQGGSAITDINGKAEVTLSGTKSGTYPVTVSVN 1831 +T + A ++ S + K T+S S T ++ Sbjct: 792 KYTWRSANPAIASV-DASSGQVTLKEKGTTTISVISSDNQTATYTIA 837
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.1 bits (65), Expect = 0.026 Identities = 22/150 (14%), Positives = 53/150 (35%), Gaps = 17/150 (11%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ I+ ++ A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL----LIMARFIQGAGAAA 119 Query: 139 VGGEWGGAALLSVESAPKNKK-AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWG 197 + + K S V +G GVG + + I Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------------H 167 Query: 198 WRIPFLFSIVLVLGALWVRNGMEESAEFEQ 227 W L ++ ++ ++ +++ + Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKG 197
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 93.7 bits (233), Expect = 5e-24 Identities = 64/347 (18%), Positives = 129/347 (37%), Gaps = 53/347 (15%) Query: 5 RIFIAGHQGMVGSAITRRLKQRD-------------DVEL------VLRTRD----ELNL 41 + + G G +G +++RL + DV L +L +++L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 42 LDSSAVLDFFSSQKIDQVYLAAAKVGGILANSSYPADFIYENIMIEANVIHAAHKNNVNK 101 D + D F+S ++V+++ + + + P + N+ N++ N + Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 102 LLFLGSSCIYPKLAHQPIMEDELLQGKLEPTNEP---YAIAKIAGIKLCESYNRQFGRDY 158 LL+ SS +Y P D + + P YA K A + +Y+ +G Sbjct: 121 LLYASSSSVYGLNRKMPFSTD-------DSVDHPVSLYAATKKANELMAHTYSHLYGLPA 173 Query: 159 RSVMPTNLYGPNDNFHPSNSHVIPALLRRFHDAVENNSPNVVVWGSGTPKREFLHVDDMA 218 + +YGP P L +F A+ + V+ G KR+F ++DD+A Sbjct: 174 TGLRFFTVYGPWGR--PD------MALFKFTKAMLEGKS-IDVYNYGKMKRDFTYIDDIA 224 Query: 219 SASIYVMEMPYDIWQKNTK---------VMLSHINIGTGIDCTICELAETIAKVVGYKGH 269 A I + ++ + T NIG + + + + +G + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 270 ITFDTTKPDGAPRKLLDVTLLHQ-LGWNHKITLHKGLENTYNWFLEN 315 +P D L++ +G+ + T+ G++N NW+ + Sbjct: 285 KNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 105 bits (263), Expect = 8e-28 Identities = 73/353 (20%), Positives = 121/353 (34%), Gaps = 42/353 (11%) Query: 6 LITGVTGQDGSYLAEFLLDKGYEVHGIKRRASSFNTERIDHIYQDPH--------GSNPN 57 L+TG G G ++++ LL+ G++V GI + N Y D + P Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLND------YYDVSLKQARLELLAQPG 53 Query: 58 FHLHYGDLTDSSNLTRILKEVQPDEVYNLAAMSHVAVSFESPEYTADVDAIGTLRLLEAI 117 F H DL D +T + + V+ V S E+P AD + G L +LE Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 118 RFLGLENKTRFYQASTSELYGLVQEIPQKESTPF-YPRSPYAVAKLYAYWITVNYRESYG 176 R ++ AS+S +YGL +++P +P S YA K + Y YG Sbjct: 114 RHNKIQ---HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 177 IYACNGILFNHESPRRGETFVTRKITRGLANIAQGLESCLYLGNMDSLRDWGHAKDYVRM 236 + A F P K T+ + +G +Y RD+ + D Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTK---AMLEGKSIDVY-NYGKMKRDFTYIDDIAEA 226 Query: 237 QWLMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKMSFVGKGIEEKGIVDSVEGQDAP 296 + D +G +E + ++E DA Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIG-----NSSPVELMDYIQALE--DAL 279 Query: 297 GVKPGDVIVAVDPRY--FRPAEVDTLLGDPSKANLKLGWRPEITLAEMISEMV 347 G++ +P +V D +G+ PE T+ + + V Sbjct: 280 GIE-------AKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 93.7 bits (233), Expect = 5e-24 Identities = 70/334 (20%), Positives = 126/334 (37%), Gaps = 62/334 (18%) Query: 4 NVLLIGASGFVGT----RLLE----------------TAIADFNIKNLDKQQSHFYPEIT 43 L+ GA+GF+G RLLE ++ ++ L + F+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK--- 58 Query: 44 QIGDVRDQQALDQALA--GFDTVVLLAAEH--RDDVSPTSLYYDVNVQGTRNVLAAMEKN 99 D+ D++ + A F+ V + R + Y D N+ G N+L N Sbjct: 59 --IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 100 GVKNIIFTSSVAVYGLNKHNP-DENHPHD-PFNHYGKSKWQAEEVLREWYNKA---PTER 154 ++++++ SS +VYGLN+ P + D P + Y +K +A E++ Y+ P Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATK-KANELMAHTYSHLYGLPA-- 173 Query: 155 SLTIIRPTVIFGERNRGN--VYNLLKQIAGGKFMMV-GAGTNYKSMAYVGNIVEFIKYKL 211 T +R ++G R + ++ K + GK + V G + Y+ +I E I Sbjct: 174 --TGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 212 KNVA-----------------AGYEVYNYVDKPDLNMNQLVAEVEQSLNKKIPSMHLPYP 254 + A Y VYN + + + + +E +L + LP Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ 291 Query: 255 LGMLGGYCFDI--LSKITGKKYAVS-SVRVKKFC 285 G + D L ++ G + VK F Sbjct: 292 PGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.002 Identities = 25/108 (23%), Positives = 47/108 (43%), Gaps = 5/108 (4%) Query: 125 EASVASAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSGDTTGIVVITQTHPIDLLFTLP 183 +A + + S I APV +V LK G +++ +T +V++ + +++ + Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQ 373 Query: 184 ESDIATVVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSLDNQIDATTG 230 DI + Q A + VEA+ T L + ++LD D G Sbjct: 374 NKDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Score = 28.6 bits (64), Expect = 0.038 Identities = 8/53 (15%), Positives = 16/53 (30%), Gaps = 5/53 (9%) Query: 4 SYKSRWVIVIVVVIAAIAAFWFWQGRNDSQSAAPG-----ATKQAQQSPAGGR 51 S + R V ++ IA G+ + + A G + + Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSI 106
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 917 bits (2372), Expect = 0.0 Identities = 298/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLP-QISDVSS 709 D F+ P I + T + F L DAL+ QL+ Q P + V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALMIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPRDAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G +A A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 777 bits (2009), Expect = 0.0 Identities = 243/877 (27%), Positives = 429/877 (48%), Gaps = 32/877 (3%) Query: 45 QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG-- 102 + T+S+++GVGDV + G+ A+R+ L+ L ++ DV + N + G Sbjct: 161 NVKDTLSRLNGVGDVQLFGAQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQL 219 Query: 103 ----ALEDGTHRWQIQTNDELKTAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAG 157 AL I K E+ + + N +G VRL DVA V ++ Sbjct: 220 GGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIA 279 Query: 158 MTNAKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEE 217 N KPA L I+ AN + T +I+AKL ELQ P + + D +P ++ S+ E Sbjct: 280 RINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHE 339 Query: 218 VEQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALT 277 V +TL ++ LV LV++LFL++ RAT+IP +AVPV L+GTFA + G+S+N L++ + Sbjct: 340 VVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMV 399 Query: 278 IATGFVVDDAIVVLENIARHL-EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLM 336 +A G +VDDAIVV+EN+ R + E + P +A + ++ ++ +++ L AVF+P+ Sbjct: 400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFF 459 Query: 337 GGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RML 392 GG G + R+F++T+ A+ +S+LV+L LTP +C +LK + GF Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTF 519 Query: 393 VALQQGYGKSLKWVLNHTRLVGMVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQ 452 Y S+ +L T ++ +A + L++ +P +F PE+D GV + IQ Sbjct: 520 DHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPA 579 Query: 453 SISFQ----AMRGKLQDFMKIIRD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRDERS-- 504 + + + ++K + +V V GF+ G N+GM F++LKP +ER+ Sbjct: 580 GATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGD 639 Query: 505 -ETAQQIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPK 563 +A+ +I R +++L K + + I G + ++ L D + + Sbjct: 640 ENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQ 696 Query: 564 IRKKLATL-----PELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQR 618 R +L + L V + ++ A+ L D++ LG+ + N ++ A G Sbjct: 697 ARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGT 756 Query: 619 QISTIYQPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVN 678 ++ K+ ++ D ++ ++K++V + G+ +P S F + Sbjct: 757 YVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLE 816 Query: 679 HQGLSAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVI 738 + I G S DA A ++ ++L P+ + + G + + + N Sbjct: 817 RYNGLPSMEIQGEAAPGTSSGDAMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPA 874 Query: 739 LIIAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI 798 L+ + V++ L LYES+ P++++ +P VG LLA LFN + ++G++ I Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 799 GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGD 858 G+ KNAI++V+FA + EA A +R RPI+MT+LA + G LPL +S G Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994 Query: 859 GSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRL 895 GS + +GI ++GG+V + LL ++ PV ++ R Sbjct: 995 GSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 49.1 bits (117), Expect = 7e-08 Identities = 13/39 (33%), Positives = 20/39 (51%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV 44 FI RP+ +L++ + + G L LPVA P + P Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPA 42
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 126 bits (317), Expect = 8e-34 Identities = 97/429 (22%), Positives = 188/429 (43%), Gaps = 23/429 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLM-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + LM L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGLSPLAITGLVAVGVVALVLYLLHARNNNRALFSLKL 257 G +L++VG+ L + + V V++ ++++ H R L Sbjct: 202 KGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSSTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYTWLSMAF 441 +Y+ L + F Sbjct: 428 LYSNLLLLF 436
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.3 bits (71), Expect = 0.009 Identities = 27/93 (29%), Positives = 34/93 (36%), Gaps = 27/93 (29%) Query: 173 LATLLAALATFLLA-------------RGLLAPVKRLVDGTHKLAAGDFTTRVTPTSEDE 219 LATL+AA A L+A V+ V H LA + P S + Sbjct: 77 LATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSFER 133 Query: 220 L-----------GKLAQDFNQLASTLEKNQQMR 241 L G L N+LA E+ QQMR Sbjct: 134 LYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.3 bits (141), Expect = 1e-12 Identities = 17/80 (21%), Positives = 40/80 (50%), Gaps = 1/80 (1%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLSYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTA 89 L I+ D+P+++++A Sbjct: 64 DLLPRIKKARPDLPVLVMSA 83
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.9 bits (77), Expect = 7e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 A S + ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.9 bits (62), Expect = 0.020 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 66 KMLLGALLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 106 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 714 bits (1844), Expect = 0.0 Identities = 241/843 (28%), Positives = 395/843 (46%), Gaps = 35/843 (4%) Query: 2 LRMTPLASAI---VALLLGIEAHAAEETFDTHFMMGGMKGEQVTNLRL--DDNQPLPGQY 56 R+ + A +AE F+ F+ + V +L + + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78 Query: 57 DIDIYVNKQWRGKYEIIVKDNPHET----CLTREIVKRLGIN-----SDNFARENQCLTF 107 +DIY+N + ++ E CLTR + +G+N N ++ C+ Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 108 EQLVQGGSYSWDIGIFRLDLAVPQAWVEELENGYVPPENWERGINAFYTSYYVSQYYSDY 167 ++ + D+G RL+L +PQA++ GY+PPE W+ GINA +Y S Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 168 KASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTDNNP-----GEWKSNTLYLEHGFSQIL 222 + GNS Y+ SGLN+ W+L + ++S ++ +W+ +LE + Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 223 GTLRIGDMYTSADIFDSVRFTGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 282 L +GD YT DIFD + F G +L D MLP+S++ F P + GIA+ A VTI+QNG+ Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 283 VVYQKEVPPGPFSISDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDF 342 +Y VPPGPF+I+D+ AG DL V++KEADGS + VPY++VP + + G ++Y Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 343 AAGRSHIEGASKQSD-FVQAGYQYGFNNLLTLYGGTMVANNYYAFTLGTGWNT-RIGAIS 400 AG A ++ F Q+ +G T+YGGT +A+ Y AF G G N +GA+S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 401 VDATKSHSKQDNGDVFDGQSYQIAYNKFLSQTSTRFGLAAWRYSSRDYRTFNDYVWANNK 460 VD T+++S + DGQS + YNK L+++ T L +RYS+ Y F D ++ Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 461 DNYRRDKNDVYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSG 516 ++ V + DYY + ++ ++Q L ++ LS + YWG S Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 517 SSKDYQLSYSNNWRRISYTLAASQAYDENHAE-EKRFNIFISIPFD--WGDDVTTPRRQI 573 + +Q + + I++TL+ S + ++ + ++IPF D + R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 574 YMSNSTTFDDQGFASNNTGLSGTVGNRDQFNYGINLSHQHQGN---ETTAGANLTWTAPA 630 S S + D G +N G+ GT+ + +Y + + G+ +T A L + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 631 ATVNGSYSQSSTYRQVGASVSGGLVAWSGGVNLANRLSETFAVMHAPGIKDAYVNGQKYR 690 N YS S +Q+ VSGG++A + GV L L++T ++ APG KDA V Q Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 691 TTNCNGVVVYDGLTPYRENHLMMDVSQSDSETELRGNRKMTAPYRGAVVLVDFDTDQRKP 750 T+ G V T YREN + +D + +L P RGA+V +F + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796 Query: 751 WFIKALRSDGQPLTFGYEVNDMHGHNIGVVGQGSQIFIRTNEIPPAVNVAIDKQQGLSCT 810 + L + +PL FG V + G+V Q+++ + V V +++ C Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 811 ITF 813 + Sbjct: 857 ANY 859
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 136 bits (344), Expect = 3e-43 Identities = 57/193 (29%), Positives = 93/193 (48%), Gaps = 27/193 (13%) Query: 8 ILSAAICLTVSGAPAWASEQQATLSAGYLHVSTNAPGSDNLNGINVKYRYEFTDT-LGLV 66 +A+ ++ + +T++ GY + + G N+KYRYE ++ LG++ Sbjct: 5 ACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNK-MGGFNLKYRYEEDNSPLGVI 63 Query: 67 TSFSYAGDRNRQITRYSDTRWHEDSVRNRWFSVMAGPSVRVNEWFSAYAMAGVAYSRVST 126 SF+Y T S T D +N+++ + AGP+ R+N+W S Y + GV Y + T Sbjct: 64 GSFTY--------TEKSRTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQT 115 Query: 127 FSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAWGAGVQFNPTESVAIDIAYEGSGSGDW 186 T+ HD S+ ++GAG+QFNP E+VA+D +YE S Sbjct: 116 --------TEYPTYKHD---------TSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSV 158 Query: 187 RTDGFIVGVGYKF 199 +I GVGY+F Sbjct: 159 DVGTWIAGVGYRF 171
>PF07675#Cleaved Adhesin Length = 1358 Score = 32.4 bits (73), Expect = 0.006 Identities = 21/102 (20%), Positives = 42/102 (41%) Query: 164 SGVIEIPGSITEENAKKLKSNWDSGYTGENAGKTAILSNGAKYNPTTFSPVDAQTALETG 223 +GV G T K++ N + + ++ P+ + PV TA G Sbjct: 286 TGVANASGVATVNMTKQITENGNYDVVITRSNYLPVIKQIQAGEPSPYQPVSNLTATAQG 345 Query: 224 ENESTEFDVTTLLRMDSERRMKTLGDAVKNTLLTPNEARKRE 265 + + ++D + + + R +K +GD + T+ N+ R E Sbjct: 346 QKVTLKWDAPSAKKAEGSREVKRIGDGLFVTIEPANDVRANE 387
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.5 bits (63), Expect = 0.008 Identities = 20/65 (30%), Positives = 34/65 (52%), Gaps = 3/65 (4%) Query: 69 EAVKEVLRSEEVRSALKQKLRHNLEARLDAEVDAILDELLGAPAAPEPEGIAGEGSASDS 128 A++++ + E L +K + L+A+L+AE A+ ++L A A E + G ASDS Sbjct: 410 AALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKL--AKQAEELAKL-RAGKASDS 466 Query: 129 GDPTP 133 P Sbjct: 467 QTPDA 471
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 26.0 bits (57), Expect = 0.024 Identities = 7/36 (19%), Positives = 17/36 (47%) Query: 38 DTFTVKVGDKELFTNRWNLQSLLLSAQITGMTVTIK 73 D F + +G+++ F + + ++AQI + Sbjct: 293 DPFVLSIGNRKKFLCQPGVVGKKIAAQILERIESTS 328
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 120 bits (303), Expect = 3e-34 Identities = 49/283 (17%), Positives = 112/283 (39%), Gaps = 40/283 (14%) Query: 3 IIIFRVLTFFFVIFSVNVVAKE----FTLDFSTAKTYVDSLNVIRSAIGTPLQTISSGGT 58 +I F V + + + A E F L +T+ +Y ++ +R A+ + Sbjct: 1 MIRFLVFSLLILTLFLTAPAVEGDVSFRLSGATSSSYGVFISNLRKALPYERKL-----Y 55 Query: 59 SLLMIDSGTGDNLFAVDVRGIDPEEGRFNNLRLIVERNNLYVTGFVNRTNNVFYRFADF- 117 + ++ S + + + + + + ++ N+YV G+ + Y F + Sbjct: 56 DIPLLRSTLPGSQRYALIHLTNYADE---TISVAIDVTNVYVMGYRA--GDTSYFFNEAS 110 Query: 118 ----SHVTFPGTTA-VTLSGDSSYTTLQRVAGISRTGMQINRHSLTTSYLDLMSHSGTSL 172 + F VTL +Y LQ AG R + + +L ++ L ++ Sbjct: 111 ATEAAKYVFKDAKRKVTLPYSGNYERLQIAAGKIRENIPLGLPALDSAITTLFYYNA--- 167 Query: 173 TQSVARAMLRFVTVTAEALRFRQIQRGFRTTLDDLSGRSYVMTAEDVDLTLNWGRLSSVL 232 S A A++ + T+EA R++ I++ +D +++ + + L +W LS + Sbjct: 168 -NSAASALMVLIQSTSEAARYKFIEQQIGKRVDK----TFLPSLAIISLENSWSALSKQI 222 Query: 233 PDYHGQDSV----------RVGRISFGSINA--ILGSVALILN 263 + + R++ +++A + ++AL+LN Sbjct: 223 QIASTNNGQFETPVVLINAQNQRVTITNVDAGVVTSNIALLLN 265
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 28.0 bits (62), Expect = 0.014 Identities = 9/37 (24%), Positives = 16/37 (43%) Query: 88 MTYMKAYQKAWKEHRDRYQQDMEKLESENMELRRKLG 124 M M+ Q + R+R D +++ E M L + Sbjct: 380 MAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEK 416
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 28.9 bits (64), Expect = 0.033 Identities = 13/80 (16%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 79 NVALALLDERERNQQYIKRRDQENEEIALTVGKLRVELEAAKSKLNEQREYYEGVIADGS 138 N + A + + + + E ++ L ++ + L+ RE + + A+ Sbjct: 274 NFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQ 333 Query: 139 KRIAELEKQCAEWERKALSN 158 K E + + +E R++L Sbjct: 334 K--LEEQNKISEASRQSLRR 351
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.6 bits (64), Expect = 0.019 Identities = 5/33 (15%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 164 WLHNLDQHLKHW-VWLILVVVL-VVGVRWWLKR 194 L + ++ + W++L ++ + R L++ Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQ 247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (283), Expect = 2e-32 Identities = 70/253 (27%), Positives = 115/253 (45%), Gaps = 12/253 (4%) Query: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWXSDEEGAKDTAREVVSHGVRAEIVQLDLG 62 ++A IT + GIG+ A LA QG I + E + + + AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 63 NLPEGAQALEKLIQRLGRIDVLVNNAGAMTKVPFLDMAFDEWRKIFTVDVDGAFLCSQIA 122 + + ++ + +G ID+LVN AG + ++ +EW F+V+ G F S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 ARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNAVA 182 ++ M+ + + G I+ + S P +AY ++K A TK + LEL + I N V+ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGAIATPM-------NGMDDSDVKPDAEP---SIPLRRFGATHEIASLVAWLCSEGANYT 232 PG+ T M + +K E IPL++ +IA V +L S A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGQSLIVDGGFML 245 T +L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.6 bits (64), Expect = 0.029 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 5/127 (3%) Query: 122 GAKAMREAVPAHLPVSVKVRLGWDSGEK-KFEIADAVQQAGATELVVHGRTKEQGY-RAE 179 G EA+ ++ + +G + E+ K EI A E+ V GR +G R Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 180 HIDWQAIGE-IRQRLNIPVIANGEIWDWQSAQECMAISGCDSVMIGRGALNIPNLSRVVK 238 ++ I E +++ L V A + + IS V+ G GAL + NL R++ Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL-LRNLDRLL- 307 Query: 239 YNEPRMP 245 E +P Sbjct: 308 MEETGIP 314
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 43.3 bits (102), Expect = 1e-06 Identities = 42/200 (21%), Positives = 79/200 (39%), Gaps = 5/200 (2%) Query: 193 RQLPITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQHASWVTAAFQIGGTLGALALG 252 R I + L ++ F S+L +L+ +P + N +WV AF + ++G G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 253 VLMDKFNPFRVLTLSYAIGAICIVMIGLSQDGLWLMALAIFGTGIGISGSQVGLNALTAT 312 L D+ R+L I V+ + L+ +A F G G + + + A Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 313 LYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNFSFDTLFFIIAVPAAISAVMLTLL 372 P ++R +I G VG GG M+A + L I I+ + + L Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGG-MIAHYIHWSYLLLI----PMITIITVPFL 185 Query: 373 ITVVRQSTSVPDSLPRAGVV 392 + ++++ + G++ Sbjct: 186 MKLLKKEVRIKGHFDIKGII 205 Score = 31.0 bits (70), Expect = 0.009 Identities = 54/355 (15%), Positives = 125/355 (35%), Gaps = 22/355 (6%) Query: 11 IDAAPVGKMQWRVIICCFLVVMLDGFDTAA-IGFIASAFSPDLQTLVFLRFLTGLGLGGA 69 I A GK+ ++ I L+ + + IGF+ +F L+ RF+ G G A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFS---LLIMARFIQGAG-AAA 119 Query: 70 MPNTIT-MTSEYLPARRRGALVTLMFCGFTLGSAFGGIVSAQLVPVIGWHGILVLGGVLP 128 P + + + Y+P RG L+ +G G + + I W +L++ + Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITI 179 Query: 129 LMLFVALLVVLPESPRWQVRRQLPQAVI-----------AKTVSAITRERYVDTHFYLIE 177 + + L+ +L + R + + ++ + S V + ++ Sbjct: 180 ITVPF-LMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVK 238 Query: 178 SASVTKGSIRQLFMGRQLPITLMLWVVF--FMSLLIIYLLSSWMPTLLNHRGIDLQHASW 235 +G+ +P + + F ++ + +M ++ + Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 236 VTAAFQIGGTLGALALGVLMDKFNPFRVLTLSYAIGAICIVMIGLSQDG-LWLMALAIFG 294 + G + G+L+D+ P VL + ++ + + W M + I Sbjct: 299 IFPGTMSVIIFGYIG-GILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVF 357 Query: 295 TGIGISGSQVGLNALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGVMMAMNF 349 G+S ++ ++ + ++ Q G+S N G G ++++ Sbjct: 358 VLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 2e-14 Identities = 22/113 (19%), Positives = 47/113 (41%), Gaps = 2/113 (1%) Query: 9 VMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGL 68 +++ DD +R + Q L G++V + A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIR 121 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.0 bits (62), Expect = 0.008 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 34 KHIVLWLGLALACLGLAMVLWLLVL-QNVPV 63 + I+ +L + L C LAM+ W + L N PV Sbjct: 15 RRILFYLLMLLFCQQLAMIFWRIGLPDNAPV 45
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.2 bits (68), Expect = 0.016 Identities = 19/124 (15%), Positives = 47/124 (37%), Gaps = 20/124 (16%) Query: 339 EMHNGKLTIVG-----RLDNLFFSGGEGIQTEEVERVIAAHPAVLQVFIVPVADKEF--- 390 E +G + G +++ + + ++++ + H +++ + + + ++ Sbjct: 19 ESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDAIKLVLDALVNSDYGVI 78 Query: 391 ---------GHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQ 441 GHR V EY SV +++ V + + L P + GIK Q Sbjct: 79 KDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDC-IELAPLHNPANI--EGIKACTQ 135 Query: 442 ALKE 445 + + Sbjct: 136 IMPD 139
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.8 bits (80), Expect = 6e-05 Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 12/79 (15%) Query: 1 MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTGDNRHIL 52 M+E D++H+ LS ++ L LR F + D + + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56 Query: 53 GWKNDELVAYARILKSDDD 71 G K++ ++ R +++ Sbjct: 57 GIKDNTVICSLRFIETKYP 75
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 250/251 (99%), Positives = 250/251 (99%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGLYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.9 bits (80), Expect = 4e-04 Identities = 26/120 (21%), Positives = 55/120 (45%), Gaps = 7/120 (5%) Query: 229 LSFAEISSVV------FILMSVYMVAKSQNSNGLQYDA-LFIPSMAFSILVFSFNGGIIS 281 LS AEI SV+ +++ Y+ + G Y + + ++ S L SF S Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTS 348 Query: 282 KIISNKVMILLGDASFSFYLVHTIVISTLSKFFNVSGLGAISVIKFIVMALFASLFISIM 341 ++ ++ +LG SF+ ++ TIV S+L + +G+ ++ F+ ++ ++ Sbjct: 349 WFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.0 bits (62), Expect = 0.037 Identities = 26/129 (20%), Positives = 55/129 (42%), Gaps = 4/129 (3%) Query: 93 GQARYQSLAAAEATGGLGSTATGNQLAAIAPTLGQNWLS--GQMNNYNNLANIGLGALTG 150 G+ Q + A A GL ++A L A A TL + LS + + I + Sbjct: 284 GKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRF 343 Query: 151 QANAGQNYANNVSQLYQQQAAASAANANKPSGLQSFATGAIGGAASGAMIGSAVPVIGTG 210 + G + + ++ +++ A A+ + L S + I AA+ +++G+ V + Sbjct: 344 KK-LGYDGDSLLAAFHKETGAIDASLTTISTVLASVS-SGISAAATTSLVGAPVSALVGA 401 Query: 211 IGALAGGVI 219 + + G++ Sbjct: 402 VTGIISGIL 410
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.0 bits (127), Expect = 9e-10 Identities = 60/268 (22%), Positives = 105/268 (39%), Gaps = 24/268 (8%) Query: 39 VAIPTILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLV 98 + +GG I W +L+ +PM I+ L L +E ++ G+ L+ Sbjct: 152 EGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKG-HFDIKGIILMS 208 Query: 99 LGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVIFLISLVIWESTSENPILDLSLFKSRNF 158 +G+ + ML F +S I +VSV+ + V +P +D L K+ F Sbjct: 209 VGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPF 258 Query: 159 TIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIG----- 213 IG++ + +G + ++P ++++ + G G M ++I IG Sbjct: 259 MIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVD 318 Query: 214 RYGNKIDMRVLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTI 273 R G + + VTF +V + S T F II+ G + ++TI Sbjct: 319 RRGPLYVLNIGVTFL----SVSFLTASFLLETTSWFMTIIIVFVLGGLSFTK--TVISTI 372 Query: 274 SFSGLPDNKFANASSMSNFFRTLSGSVG 301 S L + S+ NF LS G Sbjct: 373 VSSSLKQQEAGAGMSLLNFTSFLSEGTG 400
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.7 bits (194), Expect = 4e-18 Identities = 63/412 (15%), Positives = 122/412 (29%), Gaps = 96/412 (23%) Query: 13 RRKYFSLLVIVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVTVVNHK 71 RR I+ F+ + + ++E + + + G + I + V + K Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 72 DTNYVRQGDILVSLDKTDATIALNKA---------------------------------- 97 + VR+GD+L+ L A K Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 98 ------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDY 136 K + Q + L + AE + + Y+ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 137 NRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKANKALVM 182 R+ L + I+K + S + + I + K LV Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 183 N-------TPLNR-QPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPG 233 L + + + + + I++PV+ + Q V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 QSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNA 292 ++LM +VP + V A + + + +GQ+ I + F G +G Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK--- 404 Query: 293 FSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 340 + + +V V +S++ L PL G+++TA I T Sbjct: 405 VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.3 bits (115), Expect = 5e-09 Identities = 22/147 (14%), Positives = 52/147 (35%), Gaps = 31/147 (21%) Query: 5 IIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQVL 64 + DD + L + ++ + + + + D+V+ DV +P N +L Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDLL 66 Query: 65 ETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF- 123 ++K + ++++SA+N + AI+A++ G + Sbjct: 67 PRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDYL 102 Query: 124 --PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 103 PKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 2e-16 Identities = 30/105 (28%), Positives = 51/105 (48%) Query: 960 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNVDGFE 1019 +IL+ADD R +L + L+ GYDV ++ ++ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1020 LTRKLREQNSSLPIWGLTANAQANEREKGLNCGMNLCLFKPLTLD 1064 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>PF06580#Sensor histidine kinase Length = 349 Score = 223 bits (570), Expect = 3e-70 Identities = 60/207 (28%), Positives = 102/207 (49%), Gaps = 11/207 (5%) Query: 348 RAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTARQLIFNLSRYLRYNIE 407 ++ MA +A+L AL+++INPHF+FNALN I + I +P AR+++ +LS +RY++ Sbjct: 150 DQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209 Query: 408 LKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEV-NCCIPSLLIQPLVENAIV 466 + Q+ + EL + Y+ + +F D+L I+ + + +P +L+Q LVEN I Sbjct: 210 YSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIK 269 Query: 467 HGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERVEANEMPGNKIGLLNVHHR 526 HGI G + + + V + V +TG E GL NV R Sbjct: 270 HGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------STGTGLQNVRER 321 Query: 527 VKLLYGE--GLHIRRLEPGTEIAFYIP 551 +++LYG + + + IP Sbjct: 322 LQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 5e-11 Identities = 21/132 (15%), Positives = 57/132 (43%), Gaps = 6/132 (4%) Query: 2 KVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQHNRVDAIFLDINIPSLDG 61 +++ +D+ + L+ + V + + +++ D + D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALS--RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 V-LLAQNISQFAHKPFIVFITAWK--EHAVEAFELEAFDYILKPYQESRITGMLQKLEAA 118 LL + P +V ++A A++A E A+DY+ KP+ + + G++ + A Sbjct: 63 FDLLPRIKKARPDLPVLV-MSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 119 WQQQQTSSTPAA 130 +++ + + Sbjct: 122 PKRRPSKLEDDS 133
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 614 bits (1585), Expect = 0.0 Identities = 202/567 (35%), Positives = 331/567 (58%), Gaps = 8/567 (1%) Query: 117 LYGNVLASGVGVGTLTLLQSDSLDSYRAIPA-SAQDSTRLEHSLATLAEQLNQQLRERDG 175 + G +SGV + + ++D + + + +L +L E+L + + Sbjct: 5 ITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEA 64 Query: 176 ----ESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIIRNMEQVCAKLSASASDYL 231 + I +AHL ++ D E I+ + + A+ + + + ++Y+ Sbjct: 65 SMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYM 124 Query: 232 RERVSDIRDISEQLL-HITWPELKPRNNLVLEKPTILVAEDLTPSQFLSLDLKNLAGMIL 290 +ER +DIRD+S+++L H+ E + + T+++AEDLTPS L+ + + G Sbjct: 125 KERAADIRDVSKRVLGHLIGVETGSLATIA--EETVIIAEDLTPSDTAQLNKQFVKGFAT 182 Query: 291 EKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCGVLAINPNDAVSGYYQV 350 + GRTSH+ I++R+ IP + G G ++D G++ +NP + Y+ Sbjct: 183 DIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEE 242 Query: 351 AQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPGAFANGAEGVGLFRTEMLY 410 + +K++++ A+ + + ++D +++AANIGT + G ANG EG+GL+RTE LY Sbjct: 243 KRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY 302 Query: 411 MDRDSEPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKSIPYLNIPQEENPFLGYRAVR 470 MDRD P E+EQFEAY++V+ KP++ RT+DIGGDK + YL +P+E NPFLG+RA+R Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIR 362 Query: 471 IYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHGLDQILWVKGEIQKAIVELKRDGLRHA 530 + E +FRTQLRA+LRA+++GN ++M PM+ L+++ K +Q+ +L +G+ + Sbjct: 363 LCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVS 422 Query: 531 ETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMTQYLYAVDRNNPRVSPLYNPITPSF 590 ++I +GIMVE+PS + F EVDFFSIG+ND+ QY A DR N RVS LY P P+ Sbjct: 423 DSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAI 482 Query: 591 LRMLQQIVTTAHQRGKWVGICGELGGESRYLPLLLGLGLDELSMSSPRIPAVKSQLRQLD 650 LR++ ++ AH GKWVG+CGE+ G+ +PLLLGLGLDE SMS+ I +SQL +L Sbjct: 483 LRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLS 542 Query: 651 SEACRELARQACECRSAQEIEALLTAF 677 E + A++A +A+E+E L+ Sbjct: 543 KEELKPFAQKALMLDTAEEVEQLVKKT 569
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 2e-09 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + F R P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.024 Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 6/124 (4%) Query: 34 QQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATA 93 Q + ++ + + + E+ Q Q K AT +KA+ + + Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-EKTQEV 1122 Query: 94 DKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANR 153 K Q + +S +Q Q + + V I + D Q + + Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVN-----IKEPQSQTNTTADTEQPAKETSS 1177 Query: 154 NMTE 157 N+ + Sbjct: 1178 NVEQ 1181
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 233 bits (596), Expect = 2e-65 Identities = 201/789 (25%), Positives = 317/789 (40%), Gaps = 52/789 (6%) Query: 697 TAEGSIINGGSQIVNEGGLAENSVLNDGGTLDVREKGSATGIQQSSQGALVATTRATRVT 756 A G I G+ + + S + DGG G+ +Q R T VT Sbjct: 159 GAGGVQIERGANVT-----VQRSAIVDGGL----HIGALQSLQPEDLPPSRVVLRDTNVT 209 Query: 757 GTRADGVAFSIEQGAANNILLANGGVLTVESDTSSDKTQVNTGGREIVKTKATAT-GTTL 815 A G ++ A+ + L G + + + + + A G + Sbjct: 210 AVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAV 269 Query: 816 TGGEQIVEGVANETTINDGGIQTVSANGEAIKTTINE----GGTLTVNDNGKATDIVQN- 870 GG V G A GG V + + + + + G A + + Sbjct: 270 PGGA--VPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGA 327 Query: 871 ----SGAALQTSTANGIEISGT--HQYGTFSISGNLATNMLLENGGNLLVAIVYAGTLAD 924 SG +L N IE G +S L + L + L Sbjct: 328 RVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTL 387 Query: 925 ASVSGATGSLSLMTPRDNVTPVKLEGAIRITDSATLTIGNGVDTTLADLTAASRGSVWLN 984 + A G + + + A T T A + + + W+ Sbjct: 388 TGGADAQGDIVATELPSIPGTSIGPLDVALASQARWT-----GATRAVDSLSIDNATWVM 442 Query: 985 SNNSCAGTSNCEYRVNSLLLNDGNVYLSAQTAAPATTNGIYNTLTTNELSGSGNFYLHTN 1044 ++NS V +L L + + Q A A G + LT N L+GSG F ++ Sbjct: 443 TDNS---------NVGALRL-ASDGSVDFQQPAEA---GRFKVLTVNTLAGSGLFRMNVF 489 Query: 1045 VAGSRGDQLVVNNNATGNFKIFVQDTGVSPQSDDAMTLVKT-GGGDASFSLGNTGGFVDL 1103 D+LVV +A+G +++V+++G P S + + LV+T G A+F+L N G VD+ Sbjct: 490 ADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVDI 549 Query: 1104 GTYEYVLKSDGNSNWNLTNDVKPNPDPNPNPNPNPKPDPKPDPKPDPKPDPTPEPTPTPV 1163 GTY Y L ++GN W+L P P P P P P P P P+P P+ P P+P Sbjct: 550 GTYRYRLAANGNGQWSLVGAKAP---PAPKPAPQPGPQPPQPPQPQPEA-PAPQPPAG-- 603 Query: 1164 PEKRITPSTAAVLNMAATLP-LVFDAELNSIRERLNIMKASPHNNNVWGATYNTRNNVTT 1222 + + AAV L ++ AE N++ +RL ++ +P WG + R + Sbjct: 604 -RELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDN 662 Query: 1223 DAGAGFEQTLTGMTVGIDSPNDIPEGIATLGAFMGYSHSHIGFDRGGHGSVGSYSLGGYA 1282 AG F+Q + G +G D + G LG GY+ GF G G S +GGYA Sbjct: 663 RAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYA 722 Query: 1283 SWEHESGFYLDGVVKLNRFESNVAGKMSSGGAANGSYHSNGLGGHIETGMRFT-DGNWNL 1341 ++ +SGFYLD ++ +R E++ S G A G Y ++G+G +E G RFT W L Sbjct: 723 TYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFL 782 Query: 1342 TPYASLTGFTADNPEYHLSNGMESKSVDTRSIYRELGATLSYNMRLGNGMEIEPWLKAAV 1401 P A L F A Y +NG+ + S+ LG + + L G +++P++KA+V Sbjct: 783 EPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASV 842 Query: 1402 RKEFVDDNRVKVNNDGNFVNDLSGRRGIYQAGIKASFSSTLSGHLGVGYSHGAGVESPWN 1461 +EF V N + +L G R G+ A+ S + YS G + PW Sbjct: 843 LQEFDGAGTVHTNGIAH-RTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWT 901 Query: 1462 AVAGVNWSF 1470 AG +S+ Sbjct: 902 FHAGYRYSW 910
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.0 bits (202), Expect = 1e-20 Identities = 66/257 (25%), Positives = 119/257 (46%), Gaps = 7/257 (2%) Query: 3 QVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQEINAEYGEGTAYGFGADA 62 ++A + G Q +G + LA++G +A VD +K V + AE A F AD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAEAFPADV 66 Query: 63 TSEQSVLALSRGVDEIFVRVDLLVYSAGIAKAAFISDFQLGDFDRSLQVNLVGYFLCARE 122 ++ ++ ++ +D+LV AG+ + I +++ + VN G F +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 FSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSL 182 S+ M D G I+ + S V + Y+++K V T+ L L+LAEY I + + Sbjct: 127 VSKYM-MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 183 MLGNLLKSPMFQSL-LPQYATKLGIKPDQVEQYYIDKVPLKRGCDYQDVLNMLLFYASPK 241 G+ ++ M SL + + IK +E + +PLK+ D+ + +LF S + Sbjct: 186 SPGS-TETDMQWSLWADENGAEQVIKGS-LETFKTG-IPLKKLAKPSDIADAVLFLVSGQ 242 Query: 242 ASYCTGQSINVTGGQVM 258 A + T ++ V GG + Sbjct: 243 AGHITMHNLCVDGGATL 259
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 27.5 bits (61), Expect = 0.039 Identities = 14/56 (25%), Positives = 22/56 (39%), Gaps = 5/56 (8%) Query: 86 NNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFH---GQLAENAFEHFTF 138 +N++ LH N E+ + Q + G FR +S Q + E TF Sbjct: 5 HNLSYGNTPLH--NERPEIASSQIVNQTLGQFRGESVQIVSGTLQSIADMAEEVTF 58
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 373 bits (960), Expect = e-127 Identities = 125/388 (32%), Positives = 195/388 (50%), Gaps = 33/388 (8%) Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLK 198 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLR 318 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 379 RQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 433 ++GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 434 FAFPEVTLPPPEVAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 476 + ++ V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 477 HNWAACARMLETDVANLHRLAKRLGLKD 504 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.035 Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 7/93 (7%) Query: 3 TTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYRPNLLARNLSA 57 T++ E+AK AGV++ + + + +E P L Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 58 KSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 90 L VT + E++FH E Sbjct: 92 ILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.0 bits (59), Expect = 0.012 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Query: 12 IDGNQAKVD--VCGIQRDVDLTLVGSCDENGQPRVGQWVLVHVGFAMSVINEAEARDTLD 69 I GNQ + D G+ D L ++NG+P G W+ + + F + ++ ++ D + Sbjct: 171 IIGNQIRTDQKFMGV-FDESLKERQEAEKNGEPTGGDWLDIFLSF---IFDKKQSSDVKE 226 Query: 70 ALQN--MFDVEPDVG 82 A+ + V+PD+ Sbjct: 227 AINQEPVPHVQPDIA 241
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 389 bits (1000), Expect = e-131 Identities = 140/373 (37%), Positives = 203/373 (54%), Gaps = 39/373 (10%) Query: 350 YQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVLKQVEMVAQSDSTVLILG 409 E+ + R + E +L + + ++GRS AM + + + + Q+D T++I G Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 410 ETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRF 469 E+GTGKEL+ARA+H+ R N V +N AA+P L+ES+LFGHE+GAFTGA + GRF Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRF 227 Query: 470 ELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKIIQTDVRLIAATNRDLKKMV 529 E A+ +LFLDE+GDMP++ Q +LLRVLQ+ E+ +G I++DVR++AATN+DLK+ + Sbjct: 228 EQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSI 287 Query: 530 ADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAFTFKIARRLGRNIDSIPAETLRTL 589 FR DLYYRLNV P+ LPPLR+R EDIP L + F + A + G ++ E L + Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLDVKRFDQEALELM 346 Query: 590 SNMEWPGNVRELENVIERAVLLTRGNVLQLSL---------------------PDIALPE 628 WPGNVRELEN++ R L +V+ + +++ + Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQ 406 Query: 629 PETPPAATVVAQEG--------------EDEYQLIVRVLKETNGVVAGPKGAAQRLGLKR 674 A G E EY LI+ L T G AA LGL R Sbjct: 407 AVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQI---KAADLLGLNR 463 Query: 675 TTLLSRMKRLGID 687 TL +++ LG+ Sbjct: 464 NTLRKKIRELGVS 476
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 53.7 bits (129), Expect = 3e-14 Identities = 17/50 (34%), Positives = 28/50 (56%) Query: 1 MLTKYALVAIIVLCCTVLGFTLMVGDSLCELSIRERGMEFKAVLAYESKK 50 + + ++++C T+L FT + SLCE+ R+ E A +AYES K Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.021 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.8 bits (85), Expect = 2e-04 Identities = 45/314 (14%), Positives = 112/314 (35%), Gaps = 36/314 (11%) Query: 93 LGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 151 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 152 GHTLLAEFSPRRHRGVLLGAFSVVWT----VGYVLASIAGHHFISENPEAWRWLLASAAL 207 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 208 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVATATHKHIKTLF-- 265 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 266 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 312 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 313 LNALLIVGALLGLV-------LTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLF 365 + ++ G + ++ L L L+ + + + L +S + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTII 354 Query: 366 VLFSTTISAVSNLV 379 ++F + + V Sbjct: 355 IVFVLGGLSFTKTV 368
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (264), Expect = 2e-29 Identities = 72/257 (28%), Positives = 116/257 (45%), Gaps = 11/257 (4%) Query: 36 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANVFIPSFVKDNGETKEMIEN-QGVEVD 94 M+ ++GK A +TG G+G+A A LA GA++ + + E + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 95 FMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 154 D+ A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 155 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 214 F S +K M+ ++SG I+ + S + + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 215 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGAAVFLA 265 + N ++PG TD+ +L N Q + IP + D+ A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 266 SQASNYVNGHLLVVDGG 282 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.029 Identities = 21/103 (20%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQVA 107 G++++ + + G ++D+F R ++ ++ + +MAT P LWV+ ++ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 68.5 bits (167), Expect = 3e-16 Identities = 39/163 (23%), Positives = 82/163 (50%), Gaps = 9/163 (5%) Query: 37 IVGINIVEEFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIR 96 ++ ++ S+++W+ ++N VF S++ +K+ + + G I+ + S + Sbjct: 95 VLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMMDR-RSGSIVTVGSNPAGVPRTS 153 Query: 97 VPSYTASKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILD--- 153 + +Y +SK+ + T+ + E A++NI N ++PG T+ L ADE + +++ Sbjct: 154 MAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSL 213 Query: 154 -----RIPAGRWGLPSDLMGPVVFLASSASDYVNGYTIAVDGG 191 IP + PSD+ V+FL S + ++ + + VDGG Sbjct: 214 ETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGG 256 Score = 34.6 bits (79), Expect = 1e-04 Identities = 17/47 (36%), Positives = 27/47 (57%) Query: 3 LSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVEEFSEK 49 ++A +EGK+A +TG G+G+ +A LA G I ++ E EK Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEK 47
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 75.0 bits (184), Expect = 1e-19 Identities = 25/143 (17%), Positives = 58/143 (40%), Gaps = 5/143 (3%) Query: 22 ALSKGENLALLHGLTPDILDRIYAYAFDYHEKGNVTDAEIYYKLLCIYAFENHEYLKGFA 81 L G +A+L+ ++ D L+++Y+ AF+ ++ G DA ++ LC+ + + G Sbjct: 18 FLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLG 77 Query: 82 SVCQSKKKYQQAYDLYKLSYNYSPYDDYSVIYRMGQCQIGAKNIDNAMQCFYH----IIN 137 + Q+ +Y A Y + + +C + + A + I + Sbjct: 78 ACRQAMGQYDLAIHSYSYGAIMDI-KEPRFPFHAAECLLQKGELAEAESGLFLAQELIAD 136 Query: 138 NCEDASVKSKAQAYIELLTDNSE 160 E + ++ + +E + E Sbjct: 137 KTEFKELSTRVSSMLEAIKLKKE 159
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 34.6 bits (79), Expect = 3e-04 Identities = 22/126 (17%), Positives = 49/126 (38%), Gaps = 5/126 (3%) Query: 4 ISLLLFILLLCGCKQQE-LLNHLDQQQANDVLAVLQRHNINAEKKDQGKTGFSIYVEPTD 62 +++++ ++L L ++L Q ++A L + NI + I V Sbjct: 35 VAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPYRFANGSGA---IEVPADK 91 Query: 63 FASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKARLYSAIEQRLEQSLKIMDGIV 122 L LP + + + S +E+ A+E L ++++ + + Sbjct: 92 VHELRLRLAQQGLPKGGAVGFE-LLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVK 150 Query: 123 SSRVHV 128 S+RVH+ Sbjct: 151 SARVHL 156
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 310 bits (796), Expect = e-106 Identities = 112/340 (32%), Positives = 185/340 (54%), Gaps = 5/340 (1%) Query: 2 ANKTEKPTQKKLQDASKKGQILKSRDLTVSVIMLVG--TLYLGYVFDVHHIMSILEYILD 59 KTE+PT KK++DA KKGQ+ KS+++ + +++ L + H ++ + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 60 HNAKPDIWD---YFKAMGIGWLKTIIPFLLVCMFTTILVSWFQSKMQLATEAVKLKFDSL 116 + P + + + P L V I Q ++ EA+K + Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKKI 122 Query: 117 NPVNGLKRIFGLKTVKEFVKAILYIIFFALEIKVFWSNHKSLLFKTLDGDIISLLSDWGE 176 NP+ G KRIF +K++ EF+K+IL ++ ++ I + + L + I + G+ Sbjct: 123 NPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQ 182 Query: 177 MLFLLILYCLGSMIIVLIFDFIAEYFLFMKDMKMDKQEVKREYKEQEGNPEIKSKRRERH 236 +L L++ C +++ I D+ EY+ ++K++KM K E+KREYKE EG+PEIKSKRR+ H Sbjct: 183 ILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQFH 242 Query: 237 QEILSEQLKSDVSNSRLMIANPTHIAIGIYFKPHLSPIPLISVRETNEVALAVRKYAKEI 296 QEI S ++ +V S +++ANPTHIAIGI +K +P+PL++ + T+ VRK A+E Sbjct: 243 QEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEE 302 Query: 297 GIPIITDKKLARKIYATHRRYDYVSFENIDEILRLLLWLE 336 G+PI+ LAR +Y Y+ E I+ +L WLE Sbjct: 303 GVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLE 342
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 44.4 bits (105), Expect = 4e-09 Identities = 14/54 (25%), Positives = 25/54 (46%) Query: 1 MTHTIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTVKSALAFLILIIYF 54 + ++ A P+I ++L LGLL R A QL+ F I + + ++ Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALM 233
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 87.5 bits (217), Expect = 6e-24 Identities = 30/150 (20%), Positives = 65/150 (43%) Query: 1 MGEVILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRHPIIIVVSCALVQHYHY 60 M +V Q S L R+ P + ++P V+ + ++++ A+ Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 ELSTLNEIDIALLAAREIIIGLFIACLLASPFWIFLAIGSFIDNQRGATLSSTLDPATGV 120 + LA ++I+IG+ + + F G I Q G + ++ +DPA+ + Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 DTSELARLFNLFSAAVYLTNGGLNFILETL 150 + LAR+ ++ + ++LT G +++ L Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLL 150
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 78.7 bits (194), Expect = 4e-23 Identities = 59/86 (68%), Positives = 73/86 (84%) Query: 1 MDDIVFAGNRALYLILVMSAGPIAVATFVGLLVGLFQTVTQLQEQTLPFGVKLLCVSICF 60 MDD+VFAGN+ALYL+L++S P VAT +GLLVGLFQTVTQLQEQTLPFG+KLL V +C Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL 60 Query: 61 FLMSGWYGEKLYSFGIEMLNLAFARG 86 FL+SGWYGE L S+G +++ LA A+G Sbjct: 61 FLLSGWYGEVLLSYGRQVIFLALAKG 86
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 226 bits (577), Expect = 2e-77 Identities = 151/223 (67%), Positives = 181/223 (81%), Gaps = 5/223 (2%) Query: 1 MSNSISLIAILSLFTLLPFIIASGTCFIKFSIVFVIVRNALGLQQVPSNMTLNGVALLLS 60 M N ISLIA+L+ TLLPFIIASGTCF+KFSIVFV+VRNALGLQQ+PSNMTLNGVALLLS Sbjct: 1 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60 Query: 61 MFVMMPVGKEIYYNSQNENLSFNNVASVVNFVETGMSGYKSYLIKYSEPELVSFFEKIQK 120 MFVM P+ + Y ++E+++FN+++S+ V+ G+ GY+ YLIKYS+ ELV FFE Q Sbjct: 61 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120 Query: 121 VNSSEDNEEIIDDD-----NISIFSLLPAYALSEIKSAFIIGFYIYLPFVVVDLVISSVL 175 + E + D SIF+LLPAYALSEIKSAF IGFY+YLPFVVVDLV+SSVL Sbjct: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180 Query: 176 LTLGMMMMSPVTISTPIKLILFVAMDGWTMLSKGLILQYFDLS 218 L LGMMMMSPVTISTPIKL+LFVA+DGWT+LSKGLILQY D++ Sbjct: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIA 223
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 156 bits (395), Expect = 1e-47 Identities = 91/292 (31%), Positives = 136/292 (46%), Gaps = 13/292 (4%) Query: 35 KENGEDVALLMPEFSAKWLPIAEESGSWSGWVLLREIFPLISAELAGMALMPETERLIGE 94 + +G + L P W+ +++ WS W+ + +S LAG A+ E L+ Sbjct: 23 QRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWLEHVSPALAGAAVSAGAEHLVVP 82 Query: 95 WLSLSSSPLNLKYPELKYNRLCVGKVFDGVLSPAQPLIRIWTGELNLWLDKVTVCQYENA 154 WL+ + P L P L RLCV G P L+ I + LW + + Sbjct: 83 WLAATERPFELPVPHLSCRRLCVENPVPGSALPEGKLLHIMSDRGGLWFEHLPELPAVGG 142 Query: 155 PTLDKKSLYWPIHFVIGFSKTCYRTIVDIEVGDVLLISNNMAYAVIYNTKICDLIYPEEL 214 K L WP+ FVIG S T + I +GDVLLI + A +Y Sbjct: 143 GRP--KMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTSRA-----------EVYCYAK 189 Query: 215 KMADHFQYEEDFETDDFDIKKSESEIYDENDEQMINSFEELPVKIEFVLGKKIMNLYEID 274 K+ + E + DI+ E E + + +LPVK+EFVL +K + L E++ Sbjct: 190 KLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLAELE 249 Query: 275 ELCAKRIISLLPESEKNIEIRVNGALTGYGELVEVDDKLGVEIHSWLSGHNN 326 + ++++SL +E N+EI NG L G GELV+++D LGVEIH WLS N Sbjct: 250 AMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESGN 301
>SSPANPROTEIN#Salmonella invasion protein InvJ signature. Length = 336 Score = 49.4 bits (117), Expect = 2e-09 Identities = 31/75 (41%), Positives = 44/75 (58%), Gaps = 3/75 (4%) Query: 105 ENELTYQFQRWGQNHTVRILESSEG-IRLKPSDTLVSDRLHEAQHNDVTAQRWVLTEQDE 163 ++ LTY+FQRWG +++V I G L PS+T V RLH+ N QRW LT +D+ Sbjct: 260 DSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLHDQWQNG-NPQRWHLT-RDD 317 Query: 164 RQGQRHQPHEEQENE 178 +Q + Q H +Q E Sbjct: 318 QQNPQQQQHRQQSGE 332
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 34.7 bits (79), Expect = 2e-05 Identities = 31/101 (30%), Positives = 56/101 (55%) Query: 2 QLKNLQSLLDMKELLGEVVFRQDIFYSLRKVTVIQQQIAEINLEKQKIAERRKILNKEIV 61 Q+ L+ LLD + R++I+ LRK +++++QI ++ L+ +I E+R L K+ Sbjct: 45 QIAGLKLLLDTLRAENRQLSREEIYALLRKQSIVRRQIKDLELQIIQIQEKRSELEKKRE 104 Query: 62 QQQAQRKHWWLKGEKYDRLKKRIKKQLLNQMLYQDELEQEE 102 + Q + K+W K Y R R K+ + + + Q+E E EE Sbjct: 105 EFQEKSKYWLRKEGNYQRWIIRQKRLYIQREIQQEEAESEE 145
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 31.2 bits (70), Expect = 0.019 Identities = 18/60 (30%), Positives = 31/60 (51%), Gaps = 3/60 (5%) Query: 597 EIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLAL---SGINIPIKDIILLGSVDIRR 653 EI +R+ G A T L L ASE +N +++L + +N+ + L+G+V + R Sbjct: 202 EINNRVGSGAGRKASSTVLTLQASEGITSRENAEISLYDGATLNLASNSVKLMGNVWMGR 261
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 240 bits (613), Expect = 2e-78 Identities = 128/321 (39%), Positives = 195/321 (60%) Query: 14 AREVSRLEDIITEDNEDIEAEMPKMRDDPAGKEARFLQATDEMSAALTQFMKKKIYEEQL 73 +R+ S + D + E + P + +F+Q+TDEMSAAL QF ++ YE++ Sbjct: 16 SRQASHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSAALAQFRNRRDYEKKS 75 Query: 74 ANFLDGEEYVLEDQPIEKTDKVMEALKAATTHDYEVYSFAKKLFPDESDLVVVLRAILRK 133 +N + E VLED+ + K ++++ + + A+ LFPD SDLV+VLR +LR+ Sbjct: 76 SNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFPDPSDLVLVLRELLRR 135 Query: 134 KQISENVRLNAEALLRKVNQETTKKFINSGINSALKAKLFGQALSLNPKLLRASYRQFLM 193 K + E VR E+LL+ V ++T K + +GIN ALKA+LFG+ LSL P LLRASYRQF+ Sbjct: 136 KDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLSLKPGLLRASYRQFIQ 195 Query: 194 AEDDAVDTYVEWIGSYGYQNRMLVTKFIKETLFSDINALDASCSSLEFGMFLNKLSQLLS 253 +E V+ Y +WI SYGYQ R++V FI+ +L +DI+A DASCS LEFG L +L+QL Sbjct: 196 SESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSRLEFGQLLRRLTQLKM 255 Query: 254 LQSAEALFLKTLMNNPIIKKFISAEDYWIFFLISLIKFPETAEELLNNALVTLPADANYK 313 L+SA+ LF+ TL++ K F + E W+ ++SL++ P + LL + + ++K Sbjct: 256 LRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSLLADIIGLNALLLSHK 315 Query: 314 DKTLLLKAIYSGCTNLPFSLF 334 + L+ Y C +P SLF Sbjct: 316 EHASFLQIFYQVCKAIPSSLF 336
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 448 bits (1155), Expect = e-154 Identities = 158/536 (29%), Positives = 271/536 (50%), Gaps = 54/536 (10%) Query: 34 YVANKENLRSFFETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALIERLSAQMGLIWYD 93 YVA E+LR + +VS K +SG F+ P ++ +++ L+WY Sbjct: 38 YVAKGESLRDLLTDFGANYDATVVVSDKINDK-VSGQFEHDNPQDFLQHIASLYNLVWYY 96 Query: 94 DGKAIYIYDSSEMRNALINLRKVSTNEFNNFLKKSGLYNSRYEIKGD-GNGTFYVSGPPV 152 DG +YI+ +SE+ + LI L++ E L++SG++ R+ + D N YVSGPP Sbjct: 97 DGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWEPRFGWRPDASNRLVYVSGPPR 156 Query: 153 YVDLVVNAAKLMEQNSD--GIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLS 210 Y++LV A +EQ + + G + I L +DRT R +++ PG+A +L Sbjct: 157 YLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASASDRTIHYRDDEVAAPGVATILQ 216 Query: 211 TLLNNNIKQSTGVNVLSEISSRQQLKNVSRMPPFPGAEEDDDLQVEKIISTAGAPETDDI 270 +L++ ++ QQ+ ++ P A + Sbjct: 217 RVLSD--------------ATIQQVTVDNQRIPQ-----------------AATRASAQA 245 Query: 271 QIIAYPDTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTDLEQLGADWSG 330 ++ A P N+++V+ + ++ ++L+ LD P IE++L I+DI+ L +LG DW Sbjct: 246 RVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRV 305 Query: 331 TIKIGSSLSASFNNSG----------SISTLDG---TQFIATIQALAQKRRAAVVARPVV 377 I+ G++ +G S +D +A + L + A VV+RP + Sbjct: 306 GIRTGNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTL 365 Query: 378 LTQENIPAIFDNNRTFYTKLVGERTAELDEVTYGTMISVLPRFAARN---QIELLLNIED 434 LTQEN A+ D++ T+Y K+ G+ AEL +TYGTM+ + PR + +I L L+IED Sbjct: 366 LTQENAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIED 425 Query: 435 GNEINSDKTNVDDLPQVGRTLISTIARVPQGKSLLIGGYTRDTNTYESRKIPILGSIPFI 494 GN+ + + ++ +P + RT++ T+ARV G+SL+IGG RD + K+P+LG IP+I Sbjct: 426 GNQ-KPNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYI 484 Query: 495 GKLFGYEGTNANNIVRVFLIEPREIDERMMNNANEAAVDARAITQQMAKNKEINDE 550 G LF + VR+F+IEPR IDE + ++ A + + + + EI+++ Sbjct: 485 GALFRRKSELTRRTVRLFIIEPRIIDEGIAHHL--ALGNGQDLRTGILTVDEISNQ 538
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.7 bits (61), Expect = 0.037 Identities = 12/50 (24%), Positives = 23/50 (46%), Gaps = 9/50 (18%) Query: 3 SQTKKDIPCFRSYLPDALRLRFE---DKLTIRAIAQRLGLSHSTIHTLFQ 49 +T++ I L ALRL + ++ IA+ G++ I+ F+ Sbjct: 10 QETRQHI------LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFK 53
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 121 bits (305), Expect = 1e-37 Identities = 61/178 (34%), Positives = 89/178 (50%), Gaps = 26/178 (14%) Query: 2 SGSRLADNHTLSAGYAQSKVQDFKN-IKGVNLQYRYEWD-SPVSVVGSFSYMKGDWADSH 59 +G+ +A T++ GYAQS Q N + G NL+YRYE D SP+ V+GSF+Y + Sbjct: 18 AGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPLGVIGSFTYTEKS----- 72 Query: 60 RDEADDFYRHQADIKYYSFLAGPAYRLNDYISFYGLVGISHTKAKGDYEWRNSVGADESD 119 R + Y +YY AGPAYR+ND+ S YG+VG+ + K + E Sbjct: 73 RTASSGDY---NKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQ----------TTEYP 119 Query: 120 GYLSESVSKKSTDFAYAAGVIINPWGNMSVNVGYEGTKADIYGKHSVNGFTVGVGYRF 177 Y F+Y AG+ NP N++++ YE ++ V + GVGYRF Sbjct: 120 TY---KHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRI---RSVDVGTWIAGVGYRF 171
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 27.3 bits (60), Expect = 0.043 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 56 LRSLLPAVTFFFFTGTFFSLVLNTVGVRGTTPALLFDKIDWQGAVG 101 ++ LL +V F + SL VG P+L+ D I W+G G Sbjct: 1 MKKLLKSVLVFAALSSASSLQALPVG-NPAEPSLMIDGILWEGFGG 45
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 37.8 bits (88), Expect = 7e-05 Identities = 26/194 (13%), Positives = 58/194 (29%), Gaps = 40/194 (20%) Query: 12 TGLLLLLALAFVLFYEAINGFHDTANAVATVIY------TRAMQPQLAVVMAAFFNFFGV 65 L++AL+ +L + F + + ++A+ + V+ FF Sbjct: 30 VSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYLCFP 89 Query: 66 LLGGLSVAYAIVHML-------------------PTDLLLNMGSTHGLAMVFSMLLAAII 106 LL ++ H++ P + + S L +L ++ Sbjct: 90 LLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVL 149 Query: 107 WNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLIVSPIVG 166 ++ W + ++ L + L + +I L+V VG Sbjct: 150 LSILIWIIIKG------NLVTLLQ-------LPTCGIECITPL--LGQILRQLMVICTVG 194 Query: 167 LVIAGGLIFLLRRY 180 V+ + Y Sbjct: 195 FVVISIADYAFEYY 208
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 27.8 bits (61), Expect = 0.020 Identities = 15/48 (31%), Positives = 24/48 (50%), Gaps = 1/48 (2%) Query: 92 MTFTVGELDGVSQYLSCSLMSPLSHSMSIEEG-QRLTDDCARMILSLP 138 + V + + + L SL PL + EE +R D +R++LSLP Sbjct: 124 LALKVDNAETIKKELGLSLTEPLMEQVGTEEFIKRFGDGASRVVLSLP 171
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 533 bits (1375), Expect = 0.0 Identities = 172/397 (43%), Positives = 253/397 (63%), Gaps = 11/397 (2%) Query: 11 VLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVN-GGEPAP--LAHHSYEGA 67 +LVINCGSSS+K+ ++++ D VL G+A+ I ++ L+ N GE ++ A Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDA 62 Query: 68 LKAIAFELEKRNLN-----DSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLH 122 +K + L + + +GHR+ HGG FT S +ITD+V+ I LAPLH Sbjct: 63 IKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLH 122 Query: 123 NYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTS 182 N AN+ GI++ Q+ P V VAVFDT+FHQTM AYLY +P++YY + +R+YGFHGTS Sbjct: 123 NPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGTS 182 Query: 183 HRYVSLRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSG 242 H+YVS RA +LN + ++ HLGNG+SI AV+NG+S+DTSMG TPLEGL MGTRSG Sbjct: 183 HKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSG 242 Query: 243 DVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLR-VLEKAWHEGHERAQLAI 301 +D +S++ + N S ++ ++NK+SG+ GISG+SSD R + + A+ G +RAQLA+ Sbjct: 243 SIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLAL 302 Query: 302 KTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGVEIDTEMNNRS 361 F +R+ + I +AA++ +D I+FT GIGEN IR +++ L LG ++D E N Sbjct: 303 NVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKVR 362 Query: 362 NSFGERIVSSENARVICAVIPTNEEKMIALDAIHLGK 398 E I+S+ +++V V+PTNEE MIA D + + Sbjct: 363 GE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 778 bits (2011), Expect = 0.0 Identities = 321/849 (37%), Positives = 470/849 (55%), Gaps = 48/849 (5%) Query: 31 SGMLCTTANAEEYYFDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQK 90 + ++ E YF+P L DLSRF PGTY+VDI+LN ++ + Sbjct: 35 AFAAQAPLSSAELYFNPRFLAD--DPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATR 92 Query: 91 KITFTAN-AEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDF 149 +TF +EQ + P T QL +G+ + + DD+ + L +I A+ D Sbjct: 93 DVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVP-LTSMIHDATAQLDV 151 Query: 150 NHQRLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNM 209 QRLNL+IPQ + ARGY+ P WD GI NY+F+G+ + R G S YLN+ Sbjct: 152 GQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNL 211 Query: 210 QNGANFGPWRLRNYSTWTRNDQASS------WNTISSYLQRDIKALKSQLLLGESATSGS 263 Q+G N G WRLR+ +TW+ N SS W I+++L+RDI L+S+L LG+ T G Sbjct: 212 QSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGD 271 Query: 264 IFSSYNFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVPAGAFE 323 IF NF G QLASDDNMLP+SQRGFAP + GIA +A VTI+QNGY IY S VP G F Sbjct: 272 IFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFT 331 Query: 324 INDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDS 383 IND+Y + NSGDL+VTI+E+DG+ + F PYSS+P++QR GH +YS TAG YR+ Sbjct: 332 INDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQE 391 Query: 384 KEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDN 443 K P F ++T ++GL +T+YGG ++ Y A GIG +GALGALS+D+ +A++ + Sbjct: 392 K-PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD 450 Query: 444 QHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFDEA------------------ 485 G R Y K + E+ TNI + YRY+ GYF+F + Sbjct: 451 DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQ 510 Query: 486 ----NTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNEKNRNISVGVSGQQ 541 T ++ ++ ++Q ++Q + +LY SGS Q YWG + + G++ Sbjct: 511 VKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF 570 Query: 542 WGIGYSLNYQYSRYTDQN-NDRALSLNLSIPLERWLPRSR--------VSYQMTSQKDRP 592 I ++L+Y ++ Q D+ L+LN++IP WL SY M+ + Sbjct: 571 EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGR 630 Query: 593 TQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNS----SVNASYRSPYGTFSAGYSYGNDS 648 + + G+LL+D LSYS++ + NS +YR YG + GYS+ +D Sbjct: 631 MTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDI 690 Query: 649 SQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYL 708 Q YGV+GGV+ H +GVTL Q L + L+ A GA +++N G+ TD GYAV+PY Sbjct: 691 KQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYA 750 Query: 709 TTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPL 768 T Y+ENR+++DT L DNVDL+ VVP RGA+V A F A +G ++L+T+ N KPL Sbjct: 751 TEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL-THNNKPL 809 Query: 769 PFGALASNDDTGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTT 828 PFGA+ +++ + IV + G +YLSG+ + V+WG + + C + P Sbjct: 810 PFGAMVTSESSQSSGIVADNGQVYLSGMPLAGK-VQVKWGEEENAHCVANYQLPPESQQQ 868 Query: 829 SVLQGTAQC 837 + Q +A+C Sbjct: 869 LLTQLSAEC 877
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 29.7 bits (66), Expect = 0.043 Identities = 11/72 (15%), Positives = 24/72 (33%), Gaps = 4/72 (5%) Query: 487 AGVNGGSGIALTGTPITPRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGE 546 + V+G + + + I + + ++ T D + G R A + + Sbjct: 330 SEVHGNAEVHASFFDIGGSVSAGFSNSNSS----TVAIDHSLSLAGERTWAETMGLNTAD 385 Query: 547 IAFIKPMIAMRN 558 A + I N Sbjct: 386 TARLNANIRYVN 397
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.6 bits (61), Expect = 0.036 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 22/111 (19%) Query: 42 NKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIA-------NDRL 94 K+L GN + A T + IA + V AI+ D+ Sbjct: 277 TKVL--GNVGKGISQYIIAQRAAQGLSTSAAAAGLIA----SAVTLAISPLSFLSIADKF 330 Query: 95 HD----EVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVA 141 E Y+++ + LG+ GD LLA + A++A++T T++A Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETG-----AIDASLTTISTVLA 376
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.014 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 19 VLITGATGLVGGHLLRMLINEP 40 L+TGA G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 6e-13 Identities = 26/115 (22%), Positives = 45/115 (39%), Gaps = 4/115 (3%) Query: 528 VLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFKPGEYDLVLLDIQLPDMTGLDI 587 +L+ +D V L + G V + G+ DLV+ D+ +PD D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 588 SRELTKRYPREDLPPLVALTA-NVLKDKQEYLNAGMDDVLSKPLSVPALTAMIKK 641 + K P P++ ++A N + G D L KP + L +I + Sbjct: 66 LPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.5 bits (102), Expect = 1e-06 Identities = 41/203 (20%), Positives = 67/203 (33%), Gaps = 10/203 (4%) Query: 126 APSTTSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISST-PTQGQ 184 P+ +D + + ++A D+A PAP T S + S T Q Sbjct: 999 TPNNIQADVPSVPSNNEEIA--RVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 185 TPAATDGQQRVEVQGDLNNALTQPQN----QQQLNNVAVNSTLPTEPATVAPVRNGNASR 240 T Q R + +N Q Q +T E ATV + A Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE--KEEKAKV 1114 Query: 241 DTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAA 300 +T KTQ + + +Q+ E +PQA E P + A T+ PA Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQS-ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 301 TSTPAPKETATTAPVQTASPAQT 323 ++ ++ T + + Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVV 1196 Score = 42.4 bits (99), Expect = 4e-06 Identities = 38/199 (19%), Positives = 68/199 (34%), Gaps = 19/199 (9%) Query: 143 DLAGNATDQANGVQPAPGTTSAENTQQDVSL-----------------PPISSTPTQGQT 185 DL ++ N T+ N Q DV PP +TP++ Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 186 PAATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKT 245 A + +Q + T+ Q + S + T ++G+ +++T T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 246 QTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPA 305 +T E + + + E + V ++ P + + +P A A P Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 306 PKETATTAPVQTASPAQTT 324 +T TTA T PA+ T Sbjct: 1159 QSQTNTTA--DTEQPAKET 1175
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 32.1 bits (73), Expect = 8e-04 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%) Query: 32 FYDSDQEIEKRTGADVGWVFDLEGEEGFRD----------REEKVINELTEKQGIVLATG 81 FYD + KR + GW+ + G+R E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 82 GGSVKSRETRNRLSARGVVVYLETTIEKQLA 112 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 286 bits (734), Expect = 2e-93 Identities = 80/301 (26%), Positives = 131/301 (43%), Gaps = 18/301 (5%) Query: 117 LENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDL 176 L + I D + +A SA+ + D N +++RD+ + ++ + +D Sbjct: 219 LSDATIQQVTVDNQRIPQAAT-RASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDK 277 Query: 177 PVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNI 236 P ++E++ IV IN L ELGV W + + T G ++A+ G Sbjct: 278 PSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASN----GALG 333 Query: 237 GRINGRLLDL---ELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGAT 293 ++ R LD ++ LE + +++ P LL A I SE Y +G+ A Sbjct: 334 SLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDH-SETYYVKVTGKEVA- 391 Query: 294 SVEFKEAVLG--MEVTPTVLQKG---RIRLKLHISQNVPGQVLQQADGEVLAIDKQEIET 348 E K G + +TP VL +G I L LHI +G + I + ++T Sbjct: 392 --ELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEG-IPTISRTVVDT 448 Query: 349 QVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRL 408 V G++L +GGI+ + VPLLGDIP+ G LFR + R + I PR+ Sbjct: 449 VARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRI 508 Query: 409 V 409 + Sbjct: 509 I 509 Score = 36.8 bits (85), Expect = 2e-04 Identities = 18/95 (18%), Positives = 33/95 (34%), Gaps = 4/95 (4%) Query: 1 MKQWIAALLLMLIPGVQAA----KPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSG 56 K+ + LL+L A P + + +L +VVS ++ Sbjct: 9 FKRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIND 68 Query: 57 TVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSV 91 VS + LQ + L+ +GN+L + Sbjct: 69 KVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYI 103
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 21/92 (22%), Positives = 33/92 (35%), Gaps = 16/92 (17%) Query: 51 VACIDGDVVGHLTIDVQQRPRRSHVADFGICVDARWKNRGVASALMREMIE------MCD 104 + ++ + +G + I + + D + D R K GV +AL+ + IE C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 105 NWLRVDRIELTVFVDNAPAIKVYKKFGFEIEG 136 L I N A Y K F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 31.6 bits (71), Expect = 0.007 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 276 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 332 R P+ G+ R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 333 YAYADRSEYLGDPDFVKVPWQA 354 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 30.3 bits (68), Expect = 0.004 Identities = 13/63 (20%), Positives = 23/63 (36%), Gaps = 4/63 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129 Query: 85 YGK 87 G Sbjct: 130 GGI 132
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.010 Identities = 11/35 (31%), Positives = 19/35 (54%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTEGDICINDQR 67 +V+ G G GKSTL+ + GL+ ++ I + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.3 bits (91), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 52.8 bits (126), Expect = 3e-09 Identities = 36/183 (19%), Positives = 61/183 (33%), Gaps = 12/183 (6%) Query: 19 EQTPEKETEVQNEQTVVEEIVQAQEPVKASEQAVEE----QPQAHTEAEAET-FAADVVE 73 P T + +TV E Q + V+ +EQ E + EA++ E Sbjct: 1025 VPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE 1084 Query: 74 VTEQVAENEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAE 133 V + +E ++ Q + V +E V E+ + +VSP++ Q+E Sbjct: 1085 VAQSGSETKETQTTE--TKETATVEKEEKAKVETEKTQ---EVPKVTSQVSPKQEQSETV 1139 Query: 134 TVEIVEAAEEEAAK--EEITDEELEAQALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKP 191 + A E + +E + A E + V P E V E P Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199 Query: 192 TKE 194 Sbjct: 1200 ENT 1202 Score = 46.6 bits (110), Expect = 2e-07 Identities = 39/178 (21%), Positives = 65/178 (36%), Gaps = 20/178 (11%) Query: 22 PEKETEVQNEQTVVEEIVQAQEPVKASEQAV----EEQPQAHTEAEAETFAADVVEVTEQ 77 PE E + QTV + ++A +V EE + A E TE Sbjct: 983 PEVE---KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 78 VAENEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEI 137 VAEN K + + + + + + + + EV+ Q+ +ET E Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA----QSGSETKET 1095 Query: 138 VEAAEEEAAKEEITDEELEAQALAAEAAEEAVMV--VPP----AEEEQPVEEIAQEQE 189 +E A E +E +A+ + E + V P +E QP E A+E + Sbjct: 1096 QTTETKETATVE---KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Score = 43.5 bits (102), Expect = 2e-06 Identities = 27/157 (17%), Positives = 49/157 (31%), Gaps = 6/157 (3%) Query: 17 QKEQTPEKETE----VQNEQTVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVV 72 + ++T E E V+ E+T V +Q K EQ+ QPQA E + Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPK-QEQSETVQPQAEPARENDPTVNIKE 1157 Query: 73 EVTEQVAENEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEA 132 ++ + QP E + E V E+ V + PE+ P + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTES-TTVNTGNSVVENPENTTPATTQPTVNSESS 1216 Query: 133 ETVEIVEAAEEEAAKEEITDEELEAQALAAEAAEEAV 169 + + + + + A + Sbjct: 1217 NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLT 1253 Score = 43.1 bits (101), Expect = 2e-06 Identities = 25/176 (14%), Positives = 49/176 (27%), Gaps = 2/176 (1%) Query: 17 QKEQTPEKETEVQNEQTVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVTE 76 +E E ++ V+ E E + +E E +A+ EV Sbjct: 1065 NREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP- 1123 Query: 77 QVAENEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETVE 136 +V + E QP+ +P + +E + A+ P + + Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPT-VNIKEPQSQTNTTADTEQPAKETSSNVEQP 1182 Query: 137 IVEAAEEEAAKEEITDEELEAQALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPT 192 + E+ + + E A P + V + E T Sbjct: 1183 VTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238 Score = 30.8 bits (69), Expect = 0.016 Identities = 34/152 (22%), Positives = 52/152 (34%), Gaps = 21/152 (13%) Query: 52 VEEQPQAHTEAEAETFAADVVEVTEQVAEN-EKAQPEAEVVAQPEPVVE-ETPEPVAIER 109 VE++ Q T +V + N E A+ + V P P ET E VA Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 110 EELPLPEDVNAEEVSPEEWQAEAETVEIVEAAEEEAAKE--------EITDEELEAQALA 161 ++ ++ V E A T + E A+E A E+ E + Sbjct: 1045 KQ-------ESKTVEKNEQDATETTAQNREVAKE-AKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 162 AEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTK 193 +E V +EE+ E + QE P Sbjct: 1097 TTETKETATV---EKEEKAKVETEKTQEVPKV 1125
>PF01206#SirA family protein Length = 76 Score = 105 bits (265), Expect = 3e-34 Identities = 24/72 (33%), Positives = 41/72 (56%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRKG 80 + Y + +++ Sbjct: 65 EDGTYHFRLKRA 76
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.6 bits (121), Expect = 6e-09 Identities = 79/398 (19%), Positives = 146/398 (36%), Gaps = 32/398 (8%) Query: 13 LRLNLRILSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 70 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 71 PHAGRYADLLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 129 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 130 FAGTGSTLWGVGVVGSL--HIGRVISWNDIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 187 A G+ + + H G + + +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 188 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 240 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 241 ITLFYDVK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 296 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 297 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 355 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 356 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 389 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 31.0 bits (70), Expect = 0.015 Identities = 21/111 (18%), Positives = 42/111 (37%), Gaps = 22/111 (19%) Query: 568 VNLFSLLALVLVLGIGINYTLF--------FSNPRGTPLTSLLAIAL---------AMLT 610 +L ++ AL+ + G IN T+ + PL ++ +++ +T Sbjct: 204 FDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTGMT 263 Query: 611 TLLTLGMLVFSATQAISSFGIVLVSGIFTA-----FLLSPLAMPDKKRTKK 656 TLL L ++ I F +V G+FT ++ + + K Sbjct: 264 TLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNK 314
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.2 bits (231), Expect = 5e-25 Identities = 63/251 (25%), Positives = 119/251 (47%), Gaps = 15/251 (5%) Query: 3 RSVLVTGASKGIGRAIACQLAADGFNI-GVHYHRDATGAQETLNAIVANGGNGRLLSFDV 61 + +TGA++GIG A+A LA+ G +I V Y+ + + ++ A + DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVS--SLKAEARHAEAFPADV 66 Query: 62 ANREQCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSDDDWDAVIHTNLDSFYNVIQP 121 + E+ + G +V+ AG+ R +LSD++W+A N +N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 122 CIMPMIGARQGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCI 181 + + R+ G I+T+ S + Y+++KA + TK L +ELA+ I N + Sbjct: 127 -VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 182 APGLIDTGMIEM-------EESALKEAMSM----IPMKRMGQAEEVAGLASYLMSDIAGY 230 +PG +T M E +K ++ IP+K++ + ++A +L+S AG+ Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 231 VTRQVISINGG 241 +T + ++GG Sbjct: 246 ITMHNLCVDGG 256
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 51.1 bits (122), Expect = 2e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 201 REREHGTVEHLLVMPITPFEIMMAKI-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 259 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 260 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 318 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 319 IMLIMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 368 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.043 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 20 ARCMVGLIGPDGVGKSSLLSLISGAR 45 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 81.8 bits (202), Expect = 3e-19 Identities = 72/408 (17%), Positives = 137/408 (33%), Gaps = 81/408 (19%) Query: 6 RHLAWWGVGLLAVAAIVXWWLLRPAGVP-EGFAVSNGRIEATEVDIASKIAGRIDTILVK 64 R +A++ +G L +A I+ G +GR + I + I+VK Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVK 113 Query: 65 EGQFVREGEVLAKMDTRV----------------LQEQRLEAI----------------- 91 EG+ VR+G+VL K+ L++ R + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 -------------------AQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDSV 132 Q Q+ + L+++++E + +N+ + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 133 AKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ-- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 191 -----------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAAG 236 QT T + S ++AP +V Q +V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 237 GRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTP 295 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNINL 410 Query: 296 KTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 411 DAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.033 Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 226 ENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFL--NEQRNAHPNQSLKNTL 283 E + RG GP +L + ++ + + + L T + N Q A N LK L Sbjct: 63 EAITLRERGWKGP-ILMLEGFFHAQD---LEIYDQHRLTTCVHSNWQLKALQNARLKAPL 118 Query: 284 AVHL------------PKRLVERLQQLGQIPDVSLKQL 309 ++L P R++ QQL + +V L Sbjct: 119 DIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTL 156
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 102 bits (256), Expect = 3e-27 Identities = 76/348 (21%), Positives = 127/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLNI 47 +VTG AGFIG ++ K L + G ++ +DNL D +++ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.6 bits (74), Expect = 0.003 Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 10/117 (8%) Query: 60 HVFTDYISDKDKLYFSDL-------AKQYNSRINIYVINCDKLKSLPSTKNWTYATYFRF 112 H+ D +DKL +D+ ++ N I + S+ T+ +F Sbjct: 860 HIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKGEG--NVLSIGHKNGITFRNWFEK 917 Query: 113 IIADYFYHKHEKILYLDADIACKGSIKELLDYQFSTNEIAAVVAERDVEWWQNRASV 169 D H+ E+I I S+K+ L+YQ N A+ V D + ++ + Sbjct: 918 ESGDISNHEIEQIFDKSGRIITPDSLKKALEYQ-QRNNKASYVYGNDALAYGSQGDL 973
>SECA#SecA protein signature. Length = 901 Score = 42.2 bits (99), Expect = 7e-06 Identities = 39/129 (30%), Positives = 57/129 (44%), Gaps = 18/129 (13%) Query: 233 NLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARVVAEIERDM-ALDVPMM 291 LS L+ F A+ L + L+N + A A R ++ M DV ++ Sbjct: 37 KLSDEELKGKTAEFRAR-LEKGEVLENLIPEAF------AVVREASKRVFGMRHFDVQLL 89 Query: 292 ---RLVQGDV-----GSGKTLVAALAA-LRAIAHGKQVALMAPTELLAEQHANNFRNWFE 342 L + + G GKTL A L A L A+ GK V ++ + LA++ A N R FE Sbjct: 90 GGMVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFE 148 Query: 343 PLGIEVGWL 351 LG+ VG Sbjct: 149 FLGLTVGIN 157
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 29.7 bits (66), Expect = 0.020 Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 9/102 (8%) Query: 112 MMMVTLLSLDTSAQKVSSLKNSNEIY---MDGQTKALENKTQEYKKQLEEQQKAEEKSQK 168 M+M + + SL+N ++ +G+ +E K+ E++ EE +KAEE ++ Sbjct: 258 MLMAMFIEI-VGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQ---EETRKAEETNRI 313 Query: 169 SKIVGQVFGWLGVALTAVAAVFNPALWAVVAIGATAMALQTA 210 +G+V G L ++ VAAVF A +A+ A +A+ A Sbjct: 314 MGCIGKVLGALLTIVSVVAAVFTGG--ASLALAAVGLAVMVA 353
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 28.3 bits (63), Expect = 0.047 Identities = 43/225 (19%), Positives = 73/225 (32%), Gaps = 23/225 (10%) Query: 39 SPLINLQNELAMITSSSLSETIEGLSLGYRK---GSARKEEEGSTIEKLLNDMQELLTLT 95 + ++ E+ SE E LSL RK AR + + + L+ + EL Sbjct: 47 QSIADMAEEVTF----VFSERKE-LSLDKRKLSDSQARVSDVEEQVNQYLSKVPEL---E 98 Query: 96 DSDKIKELS--LKNSGL--LEQHDPTLAMFGNMPKGEIVALISSLLQSK--FVKIELKKK 149 + EL L NS L Q L P + L K L Sbjct: 99 QKQNVSELLSLLSNSPNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHL 158 Query: 150 YARLLLDLLGEDDWELAL-----LSWLGVGELNQEGIQKIKKLYEKAKDEDSENGASLLD 204 + L+ + E + L + +Q ++ Y A + ++ Sbjct: 159 VEQALVSMAEEQGETIVLGARITPEAYRESQSGVNPLQPLRDTYRDAV-MGYQGIYAIWS 217 Query: 205 WFMEIKDLPEREKHLKVIIRALSFDLSYMSSFEDKVKTSSIISDL 249 + + + + + +ALS DL S + K +ISDL Sbjct: 218 DLQKRFPNGDIDSVILFLQKALSADLQSQQSGSGREKLGIVISDL 262
>INTIMIN#Intimin signature. Length = 939 Score = 1459 bits (3777), Expect = 0.0 Identities = 780/942 (82%), Positives = 837/942 (88%), Gaps = 11/942 (1%) Query: 1 MITHGCYTRTRHKHKLKKTLIMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTHDSYQ 60 MITHG Y RTRHKHKLKKT IMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTH+SYQ Sbjct: 1 MITHGFYARTRHKHKLKKTFIMLSAGLGLFFYVNQNSFANGENYFKLGSDSKLLTHNSYQ 60 Query: 61 NRLFYTLKTGETVADLSKSQDINLSTIWSLNKHLYSSESEMMKAAPGQQIILPLKKLPFE 120 NRLFYTLKTGETVADLSKSQDINLSTIWSLNKHLYSSESEMMKA PGQQIILPLKKLPFE Sbjct: 61 NRLFYTLKTGETVADLSKSQDINLSTIWSLNKHLYSSESEMMKAEPGQQIILPLKKLPFE 120 Query: 121 YSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSR 180 YSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSR Sbjct: 121 YSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSR 180 Query: 181 SLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM 240 SLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM Sbjct: 181 SLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFDGSSLDFLLPFYDSEKM 240 Query: 241 LAFGQVGARYIDSRFTANLGAGQRFFLPANMLGYNVFIDQDFSGDNTRLGIGGEYWRDYF 300 LAFGQVGARYIDSRFTANLGAGQRFFLP NMLGYNVFIDQDFSGDNTRLGIGGEYWRDYF Sbjct: 241 LAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYF 300 Query: 301 KSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLIYEQYYGDNVAL 360 KSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKL+YEQYYGDNVAL Sbjct: 301 KSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVAL 360 Query: 361 FNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKSWSQQIE 420 FNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDK WSQQIE Sbjct: 361 FNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIE 420 Query: 421 PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTEHSTQKIQLIVKSKY 480 PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTE STQKIQLIVKSKY Sbjct: 421 PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHDINGTERSTQKIQLIVKSKY 480 Query: 481 GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNIYKVTARAYDRNGNSSN 540 GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSN+YKVTARAYDRNGNSSN Sbjct: 481 GLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSSN 540 Query: 541 NVQLTITVLSNGQVVDQVGVTDFTADKTSAKADNADTITYTATVKKNGVAQANVPVSFNI 600 NV LTITVLSNGQVVDQVGVTDFTADKTSAKAD + ITYTATVKKNGVAQANVPVSFNI Sbjct: 541 NVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNI 600 Query: 601 VSGTATLGANSAKTDANGKATVTLKSSTPGQVVVSAKTAEMTSALNASAVIFFDQTKASI 660 VSGTA L ANSA T+ +GKATVTLKS PGQVVVSAKTAEMTSALNA+AVIF DQTKASI Sbjct: 601 VSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASI 660 Query: 661 TEIKADKTTAVANGKDAIKYTVKVMKNGQPVNNQSVTFSTNFGMFNGKSQTQATTGNDGR 720 TEIKADKTTAVANG+DAI YTVKVMK +PV+NQ VTF+T G + + T +G Sbjct: 661 TEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLS---NSTEKTDTNGY 717 Query: 721 ATITLTSSSAGKATVSATVSDGA-EVKATEVTFFDELKID-NKVDIIGNNVRGELPNIWL 778 A +TLTS++ GK+ VSA VSD A +VKA EV FF L ID ++I+G V+G+LP +WL Sbjct: 718 AKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWL 777 Query: 779 QYGQFKLKASGGDGTYSWYSENTSIATVDA-SGKVTLNGKGSVVIKATSGDKQTVSYTIK 837 QYGQ LKASGG+G Y+W S N +IA+VDA SG+VTL KG+ I S D QT +YTI Sbjct: 778 QYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIA 837 Query: 838 APSYMI--KVDKQAYYADAMSICKNL---LPSTQTVLSDIYDSWGAANKYSHYSSMNSIT 892 P+ +I + K+ Y DA++ CKN LPS+Q L +++ +WGAANKY +Y S +I Sbjct: 838 TPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTII 897 Query: 893 AWIKQTSSEQRSGVSSTYNLITQNPLPGVNVNTPNVYAVCVE 934 +W++QT+ + +SGV+STY+L+ QNPL + + N YA CV+ Sbjct: 898 SWVQQTAQDAKSGVASTYDLVKQNPLNNIKASESNAYATCVK 939
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 122 bits (309), Expect = 4e-39 Identities = 24/125 (19%), Positives = 52/125 (41%), Gaps = 5/125 (4%) Query: 1 MSSRS-ELLLEKFAEKIGIGSISFNENRLCSFAIDEIYYISLS-DANDEYMMIYGVCGKF 58 MS+ + LL+ F+ + + + F+++ C+ ID + ++LS D E +++ G+ Sbjct: 1 MSNLFYKTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGLLEPH 60 Query: 59 PTDNSNFALEILNANLWFAENGGPYLCYEAGAQSLLLALRFPLDDATPEKLENEIEVVVK 118 +L L N GP L + + P + + L+ E+ +++ Sbjct: 61 KD---IPQQCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLE 117 Query: 119 SMENL 123 M Sbjct: 118 WMRGW 122
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 731 bits (1887), Expect = 0.0 Identities = 328/566 (57%), Positives = 390/566 (68%), Gaps = 25/566 (4%) Query: 1 MPIGNLGHNPNVNNSIPPAPPLPSQTDGA--GGRGQLINSTGPLGSRALFTPVRNSMADS 58 MPIGNLG+N N N+ IPPAPPLPSQTDGA GG G LI+STG LGSR+LF+P+RNSMADS Sbjct: 1 MPIGNLGNNVNGNHLIPPAPPLPSQTDGAARGGTGHLISSTGALGSRSLFSPLRNSMADS 60 Query: 59 GDNRASDVPGLPVNPMRLAA--SEITLNDGFEVLHDHGPLDTLNRQIGSSVFRVETQEDG 116 D+R D+PGLP NP RLAA SE L GFEVLHD GPLD LN QIG S FRVE Q DG Sbjct: 61 VDSR--DIPGLPTNPSRLAAATSETCLLGGFEVLHDKGPLDILNTQIGPSAFRVEVQADG 118 Query: 117 KHIAVGQRNGVETSVVLSDQEYARLQSIDPEGKDKFVFTGGRGGAGHAMVTVASDITEAR 176 H A+G++NG+E SV LS QE++ LQSID EGK++FVFTGGRGG+GH MVTVASDI EAR Sbjct: 119 THAAIGEKNGLEVSVTLSPQEWSSLQSIDTEGKNRFVFTGGRGGSGHPMVTVASDIAEAR 178 Query: 177 QRILELLEPKGTGESK-GAGESKGVGELRESNSGAENTTETQTSTSTSSLRSDPKLWLAL 235 +IL L+P G + +++ VG S +ET TST+ SS+RSDPK W+++ Sbjct: 179 TKILAKLDPDNHGGRQPKDVDTRSVGVGSASGIDDGVVSETHTSTTNSSVRSDPKFWVSV 238 Query: 236 GTVATGLIGLAATGIVQALALTPEPDSPTTTDPDAAASATETATRDQLTKEAFQNPDNQK 295 G +A GL GLAATGI QALALTPEPD PTTTDPD AA+A E+AT+DQLT+EAF+NP+NQK Sbjct: 239 GAIAAGLAGLAATGIAQALALTPEPDDPTTTDPDQAANAAESATKDQLTQEAFKNPENQK 298 Query: 296 VNIDELGNAIPSGVLKDDVVANIEEQAKAAGEEAKQQAIENNAQAQKKYDEQQAKRQEEL 355 VNID GNAIPSG LKDD+V I +QAK AGE A+QQA+E+NAQAQ++Y++Q A+RQEEL Sbjct: 299 VNIDANGNAIPSGELKDDIVEQIAQQAKEAGEVARQQAVESNAQAQQRYEDQHARRQEEL 358 Query: 356 KVSSGAGYGLSGALILGGGIGVAVTAALHRKNQPVEQTTTTTTTTTTTSARTVENKPANN 415 ++SSG GYGLS ALI+ GGIG VT ALHR+NQP EQTTTTTT TV + Sbjct: 359 QLSSGIGYGLSSALIVAGGIGAGVTTALHRRNQPAEQTTTTTT-------HTVVQQQTGG 411 Query: 416 TPAQGNVDTPGSEDTMESRRSSMASTSSTFFDTSSIGTVQNPYADV---KTSLHDSQVPT 472 P P RR S S +ST + SS V NPYA+V + SL Q Sbjct: 412 IPQHKVALMPQERRRFSDRRDSQGSVASTHWSDSS-SEVVNPYAEVGGARNSLSAHQPEE 470 Query: 473 SNSNTSVQNMGNTDSVVYSTIQHPPRDTTDNGARLLGNPSAGIQSTYARLALSGGLRHDM 532 + + G YS IQ+ G RL+G P GIQSTYA LA SGGLR M Sbjct: 471 HIYDEVAADPG------YSVIQNFSGSGPVTG-RLIGTPGQGIQSTYALLANSGGLRLGM 523 Query: 533 GGLTGGSNSAVNTSNNPPAPGSHRFV 558 GGLT G +AV++ N P PG RFV Sbjct: 524 GGLTSGGETAVSSVNAAPTPGPVRFV 549
>PF06704#DspF/AvrF protein Length = 129 Score = 36.4 bits (84), Expect = 6e-06 Identities = 21/119 (17%), Positives = 51/119 (42%), Gaps = 4/119 (3%) Query: 3 EKFRTDLAHTFGIALEEQTDVLSFHDNDGHEW-ILECASQSEILFFYCYLLNSESIQINS 61 + L G +L Q V + +D+ +E ++E SE++ F+C + S + Sbjct: 9 SRLIKSLGAQLGTSLTAQNGVCALYDSQDNEAAVIEMPDHSEMVIFHCRVGRSPDRAADL 68 Query: 62 ILEMNSNRELLGMF--FLSLKDDNILLNIAFPADKIDITEFANLMENGYLLKNEIIRSL 118 ++ N ++ M + ++ ++ L +D +F + G++++ R+L Sbjct: 69 QKLLSLNFDVARMHGSWFAVDQGDVRLCAQRELAVLDEAQFCDTA-RGFIVQAREARAL 126
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 55.7 bits (134), Expect = 1e-11 Identities = 32/166 (19%), Positives = 58/166 (34%), Gaps = 10/166 (6%) Query: 22 EQLYTGLTEKEANQMQALLLSNDVNVSKEMDKSGNMTLSVEKEDFVRAITILNNNGFPKK 81 L++ L++++ + A L N+ + V + L G PK Sbjct: 51 RTLFSNLSDQDGGAIVAQLTQM--NIPYRFANGSG-AIEVPADKVHELRLRLAQQGLPKG 107 Query: 82 KFADIEVIFPPSQLVASPSQENAKINYLKEQDIERLLSKIPGVIDCSVSLNVNNN----- 136 E + + S E E ++ R + + V V L + Sbjct: 108 GAVGFE-LLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVR 166 Query: 137 ESQPSSAAVLVISSPEVNLAPSVIQ-IKNLVKNSVDDLKLENISVV 181 E + SA+V V P L I + +LV ++V L N+++V Sbjct: 167 EQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLV 212
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 559 bits (1441), Expect = 0.0 Identities = 153/494 (30%), Positives = 262/494 (53%), Gaps = 24/494 (4%) Query: 30 KSEYFIITKSSPVRAILNDFAANYSIPVFISSSVNDDFSGEIKNEKPVKVLEKLSKLYHL 89 Y + K +R +L DF ANY V +S +ND SG+ +++ P L+ ++ LY+L Sbjct: 33 PIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKVSGQFEHDNPQDFLQHIASLYNL 92 Query: 90 TWYYDENILYIYKTNEISRSIITPTYLDIDSLLKYLSDTISVNKNSCNVRKITTFNSIEV 149 WYYD N+LYI+K +E++ +I + L + L + + R + + V Sbjct: 93 VWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQR-SGIWEPRFGWRPDASNRLVYV 151 Query: 150 RGVPECIKYITSLSESLDKEAQSKAKNKD--VVKVFKLNYASATDITYKYRDQNVVVPGV 207 G P ++ + + +L+++ Q +++ +++F L YASA+D T YRD V PGV Sbjct: 152 SGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASASDRTIHYRDDEVAAPGV 211 Query: 208 VSILKTMASNGSLP--STGKGAVERSGNLFDNSVTISADPRLNAVVVKDREITMDIYQQL 265 +IL+ + S+ ++ + + ++ + ADP LNA++V+D M +YQ+L Sbjct: 212 ATILQRVLSDATIQQVTVDNQRIPQAATRASAQARVEADPSLNAIIVRDSPERMPMYQRL 271 Query: 266 ISELDIEQRQIEISVSIIDVDANDLQQLGVNWSGTLNAGQGTIA--------FNSSTAQA 317 I LD +IE+++SI+D++A+ L +LGV+W + G N ++ A Sbjct: 272 IHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGA 331 Query: 318 NISSSVISNASNFMIRVNALQQNSKAKILSQPSIITLNNMQAILDKNVTFYTKVSGEKVA 377 S + RVN L+ A+++S+P+++T N QA++D + T+Y KV+G++VA Sbjct: 332 LGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSETYYVKVTGKEVA 391 Query: 378 SLESITSGTLLRVTPRILDDSSNSLTGKRRERVRLLLDIQDGNQSTNQSNAQDASSTLPE 437 L+ IT GT+LR+TPR+L S + L L I+DGNQ N S + +P Sbjct: 392 ELKGITYGTMLRMTPRVLTQGDKS-------EISLNLHIEDGNQKPNSSGIE----GIPT 440 Query: 438 VQNSEMTTEATLSAGESLLLGGFIQDKESSSKDGIPLLSDIPVIGSLFSSTVKQKHSVVR 497 + + + T A + G+SL++GG +D+ S + +PLL DIP IG+LF + VR Sbjct: 441 ISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVR 500 Query: 498 LFLIKATPIKSASS 511 LF+I+ I + Sbjct: 501 LFIIEPRIIDEGIA 514
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 139 bits (352), Expect = 4e-45 Identities = 33/142 (23%), Positives = 63/142 (44%) Query: 6 SSLEDIYDFYQDGGTLASLTNLTQQDLNDLHSYAYTAYQSGDVITARNLFHLLTYLEHWN 65 + F + GGT+A L ++ L L+S A+ YQSG A +F L L+H++ Sbjct: 10 EYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYD 69 Query: 66 YDYTLSLGLCHQRLSNHEDAQLCFARCATLVMQDPRASYYSGISYLLVGNKKMAKKAFKA 125 + L LG C Q + ++ A ++ A + +++PR +++ L G A+ Sbjct: 70 SRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFL 129 Query: 126 CLMWCNEKEKYTTYKENIKKLL 147 +K ++ + +L Sbjct: 130 AQELIADKTEFKELSTRVSSML 151
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 26.5 bits (58), Expect = 0.048 Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 4/38 (10%) Query: 115 AYNAGYFNTPNAVELRRQYAMKIYKTYNKLKNNEQIID 152 A NAGY+ TPNA + Y + K N + D Sbjct: 254 AVNAGYYVTPNA----KVYVEGAWNRVTNKKGNTSLYD 287
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 376 bits (967), Expect = e-132 Identities = 123/339 (36%), Positives = 195/339 (57%), Gaps = 4/339 (1%) Query: 2 SEKTEKPTPKKLRDLKKKGDVTKSEEVMAAVQSLILFSFFSLYGMS--FFVDIVGLVNTT 59 EKTE+PTPKK+RD +KKG V KS+EV++ LI+ L G+S +F L+ Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTA--LIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 60 IDSLNRPFLYAIREILGAVLNIFLLYILPISLIVFVGTVTTGVSQIGFIFAVEKIKPSAQ 119 + PF A+ ++ VL F P+ + + + + V Q GF+ + E IKP + Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 120 KISVKNNLKNIFSVKSIFELLKSVFKLVIIVLIFYFMGHSYANEFANFTGLNAYQALVVV 179 KI+ K IFS+KS+ E LKS+ K+V++ ++ + + ++ Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 180 AFFVFLLWKGVLFGYLLFSVFDFWFQKHEGLKKMKMSKDEVKREAKDTDGNPEIKGERRR 239 + L G+++ S+ D+ F+ ++ +K++KMSKDE+KRE K+ +G+PEIK +RR+ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 240 LHSEIQSGSLANNIKKSTVIVKNPTHIAICLYYKLGETPLPLVIETGKDAKALQIIKLAE 299 H EIQS ++ N+K+S+V+V NPTHIAI + YK GETPLPLV DA+ + K+AE Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 300 LYDIPVIEDIPLARTLYKNIHKGQYITEDFFEPVAQLIR 338 +P+++ IPLAR LY + YI + E A+++R Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLR 339
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 155 bits (394), Expect = 1e-48 Identities = 46/230 (20%), Positives = 102/230 (44%), Gaps = 4/230 (1%) Query: 11 SFYCILRPLGMFIILPIFSTGVLLSNFIRNSIMIAFTLPIIVENYTFSEKLPSGIFQLTG 70 F+ +LR L + PI S + R + +A + + + +P F Sbjct: 16 YFWPLLRVLALISTAPILSERSVPK---RVKLGLAMMITFAIAPSLPANDVPVFSFFALW 72 Query: 71 IALKEISIGFFIGLSFTILFWAIDAAGQIIDTLRGSTISSIFNPSISDSSSITGVILYQF 130 +A+++I IG +G + F A+ AG+II G + ++ +P+ + + I+ Sbjct: 73 LAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDML 132 Query: 131 ISVIFVIHGGIQSILDKLYLSYEILPLQADIAFNRALIDFLFSLWDSFIKLMLSFSVPMI 190 ++F+ G ++ L ++ LP+ + + A + + F+ L ++P+I Sbjct: 133 ALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFL-NGLMLALPLI 191 Query: 191 IGIFLCDMGFGFLNKTAPQLNVFTLSLPVKSLIAIFILLLVIHVFPDFIT 240 + ++ G LN+ APQL++F + P+ + I ++ ++ + F Sbjct: 192 TLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCE 241
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 69.0 bits (169), Expect = 2e-19 Identities = 25/78 (32%), Positives = 45/78 (57%) Query: 7 VQLCVQTFWIIFILSLPTVIAASVIGIIISLVQAITQLQDQTLPFLLKIIAVFATLALTY 66 V + +++ ILS I A++IG+++ L Q +TQLQ+QTLPF +K++ V L L Sbjct: 5 VFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLS 64 Query: 67 HWMGTTIINFSSIIFEMI 84 W G ++++ + + Sbjct: 65 GWYGEVLLSYGRQVIFLA 82
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 223 bits (570), Expect = 2e-76 Identities = 89/212 (41%), Positives = 136/212 (64%), Gaps = 9/212 (4%) Query: 12 IFLIIVFFLLSLLPIFVVIGTSFLKISIVLGILKNALGIQQVPPNMALTSVSLILTMFIM 71 I LI + +LLP + GT F+K SIV +++NALG+QQ+P NM L V+L+L+MF+M Sbjct: 5 ISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVM 64 Query: 72 SPIILQINDNISQEPINYTDSDFFQKVDEKILSPYRGFLEKNTEKDNVEFFERAAQKKLG 131 PI+ E + + D K ++ L YR +L K ++++ V+FFE A K+ Sbjct: 65 WPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQY 124 Query: 132 NETI---------LKKDSLFILLPAFTMGQLEAAFKIGFLLYLPFIAIDLIISNILLALG 182 E ++K S+F LLPA+ + ++++AFKIGF LYLPF+ +DL++S++LLALG Sbjct: 125 GEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLALG 184 Query: 183 MMMVSPVTISIPFKILLFILVGGWQKLFEFLL 214 MMM+SPVTIS P K++LF+ + GW L + L+ Sbjct: 185 MMMMSPVTISTPIKLVLFVALDGWTLLSKGLI 216
>PF06872#EspG protein Length = 398 Score = 724 bits (1871), Expect = 0.0 Identities = 293/397 (73%), Positives = 338/397 (85%) Query: 1 MILVAKLFITNQIGESLMINGLNNDSASLVLDAAMKVNSGFKKSWDEMSCAEKLFKVLSF 60 MILV K+F+ ++ + M+NGLNN+SASLVLDA +K+NS +KK W+EM+CAEKL K+L+ Sbjct: 1 MILVIKIFVIDETERAFMLNGLNNNSASLVLDATIKINSDYKKPWNEMTCAEKLLKILTL 60 Query: 61 GLWNPTYSRSERQSFQELLTVLEPVYPLPNELGRVSARFSDGSSLRISVTNSELVEAEIR 120 GLWNP YS+ ERQ FQ LLTVLEPV P NELGRV A+FSDGSSLRISVTNSEL+EAEI Sbjct: 61 GLWNPKYSQDERQQFQGLLTVLEPVSPAHNELGRVYAKFSDGSSLRISVTNSELIEAEIH 120 Query: 121 TANNEKITVLLESNEQNRLLQSLPIDRHMPYIQVHRALSEMDLTDTTSMRNLLGFTSKLS 180 T NNEK VLLE+NEQNRLLQSLPI+RHMPYIQVH L + +LTD SM LL FTSKLS Sbjct: 121 TPNNEKFLVLLEANEQNRLLQSLPINRHMPYIQVHHTLPQEELTDLLSMHKLLSFTSKLS 180 Query: 181 TTLIPHNAQTDPLSGPTPFSSIFMDTCRGLGNAKLSLNGVDIPANAQKLLRDALGLKDTH 240 TLIPHN QTDPLSG TPFS++FMDT RGLGN+KLSLNGVDIPA+AQKLLR+ LGLKDT+ Sbjct: 181 ATLIPHNNQTDPLSGLTPFSTVFMDTSRGLGNSKLSLNGVDIPADAQKLLRNTLGLKDTN 240 Query: 241 SSPTRNVIDHGISRHDAEQIARESSGSDKQKAEVVEFLCHPEAATAICSAFYQSFNVPAL 300 SSP NVI +GI RH AEQI +ESS +++QKA VV+FLC PEA TAICSAFYQSFNVPAL Sbjct: 241 SSPDLNVIRNGIPRHYAEQIVKESSSTNEQKAAVVDFLCQPEAPTAICSAFYQSFNVPAL 300 Query: 301 TLTHERISKASEYNAERSLDTPNACINISISQSSDGNIYVTSHTGVLIMAPEDRPNEMGM 360 LTH RIS+AS YNA+RSLD PNACINISI+QSS+G+I+VTSHTGVLIMAPEDRPN++GM Sbjct: 301 MLTHVRISQASAYNAQRSLDMPNACINISITQSSEGSIHVTSHTGVLIMAPEDRPNQLGM 360 Query: 361 LTNRTSYEVPQGVKCIIDEMVSALQPRYAASETYLQN 397 LTNRTSYEVP GVKC +EM L+ +YA+SETYL N Sbjct: 361 LTNRTSYEVPPGVKCEPNEMARMLKAKYASSETYLNN 397
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 28/142 (19%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 308 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIEESALSENQRVTLFRVCQEGLNN 367 LR ++L + + ++L L++ + + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 368 IVKHA-----DASAVTLQGWLQDERLMLVIEDDGSGLPPGSGQ-QGFGLTGMRERVTALG 421 +KH + L+G + + L +E+ GS + + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 422 G---TLTISCLHG-TRVSVSLP 439 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 874 bits (2260), Expect = 0.0 Identities = 547/548 (99%), Positives = 548/548 (100%) Query: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKL 60 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKL Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKL 60 Query: 61 ISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGP 120 ISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGP Sbjct: 61 ISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQAQSGLTGRDGP 120 Query: 121 DNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNV 180 DNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNV Sbjct: 121 DNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNTFTKTFVLKRGDYAVNVNYNV 180 Query: 181 QNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD 240 QNAGEKPLEIS+FGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD Sbjct: 181 QNAGEKPLEISSFGQLKQSITLPPHLDTGSSNFALHTFRGAAYSTPDEKYEKYKFDTIAD 240 Query: 241 NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQT 300 NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQT Sbjct: 241 NENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYTANLGNGIAAIGYKSQPVLVQPGQT 300 Query: 301 GAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIII 360 GAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIII Sbjct: 301 GAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIII 360 Query: 361 ITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPL 420 ITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPL Sbjct: 361 ITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPL 420 Query: 421 GGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK 480 GGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK Sbjct: 421 GGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYILPILMGVTMFFIQK 480 Query: 481 MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGL 540 MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGL Sbjct: 481 MSPTTVTDPMQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGL 540 Query: 541 HSREKKKS 548 HSREKKKS Sbjct: 541 HSREKKKS 548
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 25.4 bits (55), Expect = 0.018 Identities = 9/44 (20%), Positives = 16/44 (36%) Query: 19 LKDVMMQLEAKNNEGKYVISKANGNPVFKELFWKAIDEFNFPQE 62 ++ V+ QL+A + S F A+D + Q Sbjct: 6 IEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQT 49
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.4 bits (131), Expect = 3e-10 Identities = 61/257 (23%), Positives = 97/257 (37%), Gaps = 10/257 (3%) Query: 2 SRFLICSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAFSVYLAGMAAAML----F 57 +R LI + V L GI + + LP + DL S + + + LA A Sbjct: 4 NRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSN-DVTAHYGILLALYALMQFACAPV 62 Query: 58 AGKVADRSGRKPVAIPGAALFIITSVFCSLAETSTLFLAGRFLQGLGAGCCYVVAFAILR 117 G ++DR GR+PV + A + + A + GR + G+ G VA A + Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIA 121 Query: 118 DTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLFWTMAIMGIAVLMLSLFI 177 D D RA+ ++ V PVLG L M F + F+ A + + F+ Sbjct: 122 DITDGDERARHFGFMSACFGFGMVAGPVLGGL-MGGFSPHAPFFAAAALNGLNFLTGCFL 180 Query: 178 LKETRPAAPAASDKSRENSESLLNRFFLSRVVITTLSVSVILTFVNTSPVLLMEIMGFER 237 L E+ + N + VV ++V I+ V P L I G +R Sbjct: 181 LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDR 240 Query: 238 GEYATIMALTAGVSMTV 254 + G+S+ Sbjct: 241 FHWDATT---IGISLAA 254
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 32.0 bits (72), Expect = 0.002 Identities = 38/169 (22%), Positives = 67/169 (39%), Gaps = 11/169 (6%) Query: 189 LYANISSTTTRGEAIAKVRISGSLTAPQSCQINAGQVIYFDFDTIPASEFSSTAGQAITS 248 L+ ++ T+ A ++ I G++ P C IN GQ I DF I ++ G+ Sbjct: 6 LFISLLLTSVAVLADVQINIRGNVYIP-PCTINNGQNIVVDFGNINPEHVDNSRGE---- 60 Query: 249 RKITKTVSIECTGMGYERTQKVDASFTGTNRSSDDTMVATDNADVGIKIYNKSNAEVSVN 308 +TK +SI C KV + G + + ++AT+ GI +Y + Sbjct: 61 --VTKNISISCPYKSGSLWIKVTGNTMGVGQ---NNVLATNITHFGIALYQGKGMSTPLT 115 Query: 309 NGKLPADMGNTTI-FGRKNGSVTFSAAPASFTGARPQPGVFNATATLTI 356 G + T + TF++ P G F TA++++ Sbjct: 116 LGNGSGNGYRVTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSM 164
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 769 bits (1986), Expect = 0.0 Identities = 329/875 (37%), Positives = 481/875 (54%), Gaps = 58/875 (6%) Query: 6 LFITLASGICLLCSISAFARDSLFNPRLLELDHPADNIDIHQFNRSNTLPAGTYKVDVMI 65 F+ L + + FNPR L D P D+ +F LP GTY+VD+ + Sbjct: 26 FFVRLFVACAFAAQAPLSSAELYFNPRFLADD-PQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 66 NGMLFERQEVKFAQDNPDAELHPCYVAIKNVLATYGIKVDAIKSLANVDDKTCVNPVPLI 125 N ++V F + + + PC LA+ G+ ++ + + D CV +I Sbjct: 85 NNGYMATRDVTFNTGDSEQGIVPCLTR--AQLASMGLNTASVSGMNLLADDACVPLTSMI 142 Query: 126 DGATWLLDASKLALNITIPQIYLNNAVNGYISPSRWDQGINAMMMNYDFSASHTIRSNYD 185 AT LD + LN+TIPQ +++N GYI P WD GINA ++NY+FS + ++ Sbjct: 143 HDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV-QNRIG 201 Query: 186 DDDDSYYLNLRNGINLGAWRFRNYSTLN------SYDGNVDYHSVSNYIQRDIMALRSQI 239 + YLNL++G+N+GAWR R+ +T + S + ++ +++RDI+ LRS++ Sbjct: 202 GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRL 261 Query: 240 MIGDTWTASDVFDSTQVRGVRLYTDDDMLPSSQNGFAPVVHGIAKTNATVIIKQNGYVIY 299 +GD +T D+FD RG +L +DD+MLP SQ GFAPV+HGIA+ A V IKQNGY IY Sbjct: 262 TLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIY 321 Query: 300 QSAVPQGAFALTDLNTTSSGGDLDVTIKEEDGSEQHFIQPFTSLAILKREGQTDVDLSIG 359 S VP G F + D+ + GDL VTIKE DGS Q F P++S+ +L+REG T ++ G Sbjct: 322 NSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAG 381 Query: 360 EVR--DESGFTPEVLQLQAMHGFPLGITLYGGTQLANDYASAALGIGKDMGALGAISFDV 417 E R + P Q +HG P G T+YGGTQLA+ Y + GIGK+MGALGA+S D+ Sbjct: 382 EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDM 441 Query: 418 THARSQFDYDDNESGQSYRFLYSKRFEDTNTTFRLVGYRYSMEGFYTLNEWVSRQDNDSD 477 T A S D GQS RFLY+K ++ T +LVGYRYS G++ + + N + Sbjct: 442 TQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYN 501 Query: 478 -----------------FWVTGNRRSRFEGTWTQSFTPGWGNIYLTFSRQEYWQTDEVER 520 + + N+R + + T TQ +YL+ S Q YW T V+ Sbjct: 502 IETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYWGTSNVDE 560 Query: 521 LLQFGYNNNWRNISWNVSWNYTDSIKRSLGNHHDDNNDDFGKEQIFMFSMSIPLSCWMED 580 Q G N + +I+W +S++ T ++ G++Q+ +++IP S W+ Sbjct: 561 QFQAGLNTAFEDINWTLSYSLT----KNAWQK--------GRDQMLALNVNIPFSHWLRS 608 Query: 581 --------SYVNYSLTQNNHHESTMQVGLNGTMLEGRNLSYNVQESWMHSPDDSYSGNAG 632 + +YS++ + + T G+ GT+LE NLSY+VQ + D SG+ G Sbjct: 609 DSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGY-AGGGDGNSGSTG 667 Query: 633 ---MTYDGTYGSVNGSYSWSRDSQHFDYGARGGVLVHSDGVTFSQELGETVALVKAPGAE 689 + Y G YG+ N YS S D + YG GGVL H++GVT Q L +TV LVKAPGA+ Sbjct: 668 YATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAK 727 Query: 690 GLSIENATGISTDWRGYTVKTQLSPYDENRVALNSDYFSKANIELENTVINLVPTRGAVV 749 +EN TG+ TDWRGY V + Y ENRVAL+++ + N++L+N V N+VPTRGA+V Sbjct: 728 DAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLA-DNVDLDNAVANVVPTRGAIV 786 Query: 750 KAEFVTHVGYRVLFNVRQVNGKPIMFGAMATASLETGTVTGIVGDNGELYLSGMPEKGEF 809 +AEF VG ++L + N KP+ FGAM T E+ +GIV DNG++YLSGMP G+ Sbjct: 787 RAEFKARVGIKLLMTLTH-NNKPLPFGAMVT--SESSQSSGIVADNGQVYLSGMPLAGKV 843 Query: 810 LLSWGQAADEKCKAAYHITHKPDDTSLVQMDAICR 844 + WG+ + C A Y + + L Q+ A CR Sbjct: 844 QVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.004 Identities = 11/71 (15%), Positives = 29/71 (40%) Query: 13 AKARRKTREELNQEARDRKRQKKRRGHAPGSRAAGGNNTSGSKGQNAPKDPRIGSKTPIP 72 +K + + EE+ + + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 73 LGVTEKVTKQH 83 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 601 bits (1552), Expect = 0.0 Identities = 205/478 (42%), Positives = 299/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGXEVLEALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL + S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 28.3 bits (63), Expect = 0.042 Identities = 34/190 (17%), Positives = 72/190 (37%), Gaps = 41/190 (21%) Query: 171 IIEQADRLRNLVDRL---LGPQLPGTRVTE-SIHKVAERV---VTLVSMELPDNVRLIRD 223 I+E + R ++ L + L + + S+ V + L S++ D ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 224 YDPSLPELAHDPDQIEQVLLN-IVRNALQ---ALGPEGGEIILRTRTAFQLTLHGERYRL 279 +P++ ++ Q+ +L+ +V N ++ A P+GG+I+L+ Sbjct: 246 INPAIMDV-----QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGT------KDNGTVT- 293 Query: 280 AARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGK---IEFTSWP 336 ++VE+ G + ++ TG GL R + G I+ + Sbjct: 294 ---LEVENTGSLALKNTKE------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 337 GHTEFSVYLP 346 G V +P Sbjct: 339 GKVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.017 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 81 T +++ G +G GK +AR K N PF+ + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 41.2 bits (96), Expect = 4e-06 Identities = 32/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTTAQSKPQQAAPVTRA 232 T E++ Q T T+Q V + + + A+TQ + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.020 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 17 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 48 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.9 bits (67), Expect = 0.006 Identities = 6/21 (28%), Positives = 11/21 (52%) Query: 179 FGNLDDPNSEISQLLRQKPTY 199 GNL++P ++ L+ P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 80.3 bits (198), Expect = 9e-19 Identities = 53/363 (14%), Positives = 118/363 (32%), Gaps = 78/363 (21%) Query: 8 APRSKFPALLVVALALVALVFVIW-RVDS-APSTNDAYVSADTIDVVPEVSGRIVELAVT 65 + R + A ++ ++A + + +V+ A + S + ++ P + + E+ V Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 66 DNQAVKQGDLLFRIDPRPYEANLAKSEAS-----LAALDKQIM----------------- 103 + ++V++GD+L ++ EA+ K+++S L QI+ Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 104 -----------LTQRSVDAQQFGA-------------------DSVNATVEKARAAAKQA 133 L S+ +QF +V A + + ++ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 134 TDTLRRTEPLLKEGFVSAEDVDRARTAQRAAEADLNAVLLQAQSAASAVSGVDALVAQR- 192 L LL + ++ V A +L Q + S + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 193 ------------------AAVEADIALTKLHLEMATVRAPFDGRVISLKT-SVGQFASAM 233 + ++A + + + +RAP +V LK + G + Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 RPIFTLIDTRHWYVI-ANFRETDLKNIRSGTPATIRLMSDSGKTF---EGKVDSIGYGVL 289 + ++ + A + D+ I G A I++ + + GKV +I + Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413 Query: 290 PDD 292 D Sbjct: 414 EDQ 416
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 5e-20 Identities = 33/112 (29%), Positives = 52/112 (46%), Gaps = 1/112 (0%) Query: 16 DDTAICALLQDVLSEHVFTVSVCHTGQEAILRIEGDPDIALVVLDMMLPDTNGLRVLQQI 75 DD AI +L LS + V + I LVV D+++PD N +L +I Sbjct: 11 DDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDENAFDLLPRI 69 Query: 76 QKLRPTLPVVMLTGMGSESDVVVGLEMGADDYICKPFTPRVVVARLKAVLRR 127 +K RP LPV++++ + + E GA DY+ KPF ++ + L Sbjct: 70 KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 28.7 bits (64), Expect = 0.027 Identities = 15/65 (23%), Positives = 24/65 (36%), Gaps = 5/65 (7%) Query: 55 KLAGDNVKVTLVSSGYDLGQQVSQIDNFIAANVDMIIL---NAADSKGIGPAVKRAKDAG 111 L +KV + I I VD+I + D + AVK+A + Sbjct: 111 DLLI--IKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEAVKKAVASQ 168 Query: 112 IVVVA 116 I+V+ Sbjct: 169 ILVMC 173
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 28.3 bits (63), Expect = 0.047 Identities = 16/73 (21%), Positives = 27/73 (36%), Gaps = 1/73 (1%) Query: 219 FVYGMSGLLSGLGGIMSASRLYSANGNLGMG-YELDAIAAVILGGTSFVGGIGTITGTLV 277 ++G+ + GG A R + N +G L A++ + S + G V Sbjct: 400 LLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSV 459 Query: 278 GALIIATLNNGMT 290 L +LN T Sbjct: 460 RFLYNKSLNESGT 472
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.3 bits (141), Expect = 6e-11 Identities = 21/81 (25%), Positives = 44/81 (54%), Gaps = 2/81 (2%) Query: 643 VLVLEDEAAVRQTICEQLHLLGYLTLEASSGEQALDLLAASAEIDIFISDLMLPGGMSGA 702 +LV +D+AA+R + + L GY S+ +AA + D+ ++D+++P + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMP-DENAF 63 Query: 703 EVVNAARKLYPHLTLLLISGQ 723 +++ +K P L +L++S Q Sbjct: 64 DLLPRIKKARPDLPVLVMSAQ 84
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 25.9 bits (57), Expect = 0.034 Identities = 17/107 (15%), Positives = 41/107 (38%), Gaps = 8/107 (7%) Query: 11 TLLTLTTVPAQADIIDDTIGNIQ--------QAINDASNPDRGRDYEDSRDDGWQREVSD 62 LL LT + A+AD + +Q Q ++ + ++ + + + +Q + Sbjct: 123 VLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEE 182 Query: 63 DRRRQYDDRRRQFEDRRRQLDDRQHQLNQERRQLEDEERRMEDEYGQ 109 + R + QF + Q ++ L+++R + R+ Sbjct: 183 EVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENL 229
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 2e-04 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 15 HLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAG 74 L L+ +G I + + N I+++ V R VG+ LL A E A++ Sbjct: 68 FLYYLENNCIGRIKIRSNW-----NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 75 AEMTELSTNVKRHDAHRFYLREGY 98 L T A FY + + Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.015 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 89 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 90 TTVGWVSQFL 99 V F Sbjct: 656 ADAEAVKAFF 665
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 4e-16 Identities = 31/109 (28%), Positives = 50/109 (45%), Gaps = 4/109 (3%) Query: 4 VLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIFNSDTPIDLILLDIYMQKEN 63 +L+ DDDA + + + +++ G+ S I + DL++ D+ M EN Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 64 GLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVDYLIKPFQASR 112 DLLP + AR V+V+S+ T + G DYL KPF + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTE 110
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 7e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.4 bits (58), Expect = 0.012 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 32 LAIIEHTDVDESLKGQGIGKQLVAKVVE 59 A+IE V + + +G+G L+ K +E Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIE 116
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.8 bits (121), Expect = 2e-08 Identities = 50/312 (16%), Positives = 105/312 (33%), Gaps = 18/312 (5%) Query: 121 SRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDS 180 + ++ QERA + N L + +D ++ LT L+ + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTE---ELSNAKEKLRKND 105 Query: 181 ARLKALVDEL-ELAQLSANNRQELARLRSELAEKES--QQLDAYLQALRNQLNSQRQLEA 237 L ++ EL A+ + L + + + L+A AL + + + Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKAL 164 Query: 238 ERALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVR 297 E A+ + + L + A EL AL +++ + ++ + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 298 QALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQ 357 L + L + A A++ L + L+ A+L + Sbjct: 225 ARKADLEKA---LEGAMNFSTADSAKIKTLEA--EKAALEARQAELEKALEGAMNFSTAD 279 Query: 358 PLLRQIHQADGQPLTAE------QNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSN 411 + +A+ L AE Q+++L A ++ R L++ + L E KL+ N Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Query: 412 GQLEDALKEVNE 423 E + + + Sbjct: 340 KISEASRQSLRR 351 Score = 42.7 bits (100), Expect = 6e-06 Identities = 48/239 (20%), Positives = 92/239 (38%), Gaps = 23/239 (9%) Query: 20 ATAPDSKQITQELEQAKAAKPAQPEVVEALQSALNALEERKGSLER-IKQYQEVIDNYPK 78 A A + + LE A A ++ L++ ALE R+ LE+ ++ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 79 LSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSL 138 TL A+ + E + + Q + LD SR+A+++ E + + Sbjct: 282 KIKTLEAEKAALEAEKADL---EHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Query: 139 NQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDSARLKAL--VDELELAQLS 196 N++ ++A RQ + R L L+++ +L+ + E L Sbjct: 339 NKI----SEASRQ--SLRRDLDASR-------EAKKQLEAEHQKLEEQNKISEASRQSLR 385 Query: 197 AN---NRQELARLRSELAEKESQQLDAYLQALRNQLNSQRQLEAERALESTELLAENSA 252 + +R+ ++ L E S +L A + + S++ E E+A +L AE A Sbjct: 386 RDLDASREAKKQVEKALEEANS-KLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443
>SECA#SecA protein signature. Length = 901 Score = 32.2 bits (73), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.028 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 165 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 218 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.034 Identities = 6/19 (31%), Positives = 7/19 (36%), Gaps = 2/19 (10%) Query: 105 FNGDVQI--ELTGYWTWEQ 121 F G + L W EQ Sbjct: 62 FKGQEDLGNGLKAIWQVEQ 80
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 25.4 bits (55), Expect = 0.026 Identities = 8/23 (34%), Positives = 16/23 (69%) Query: 18 VQEIDYEDIATLKNYITESGKIV 40 +Q + Y D+AT N +++ GK++ Sbjct: 48 LQSVSYTDLATQLNDVSDFGKMI 70
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.6 bits (214), Expect = 1e-22 Identities = 67/250 (26%), Positives = 114/250 (45%), Gaps = 24/250 (9%) Query: 6 GKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAAERLAQETGATAVFT-----DS 60 GK I G ++GIG A+ R + GA++ + + E++ A A D Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 61 ADRDAVIDVV----RKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVE 116 D A+ ++ R+ G +DILV AG+ G L+ ++ + F +N ++AS Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 117 AARQMP--EGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVV 174 ++ M G I+ +GS N +P MAAYA+SK+A + L + I N+V Sbjct: 127 VSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 175 QPGPIDTDA--------NPANGPMRDMLHSF---MAIKRHGQPEEVAGMVAWLAGPEASF 223 PG +TD N A ++ L +F + +K+ +P ++A V +L +A Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 224 VTGAMHTIDG 233 +T +DG Sbjct: 246 ITMHNLCVDG 255
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 33.2 bits (75), Expect = 0.003 Identities = 30/125 (24%), Positives = 56/125 (44%), Gaps = 2/125 (1%) Query: 138 IIFPQPDGSTNRYERKSFERKDESSLHLITNKVLACYQR--EANKEIARLLNNHQKLNNL 195 +I PD ++K+ E++ E+ + +R E K A L N ++N Sbjct: 131 LIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNP 190 Query: 196 QKLNNLQKLNNLQKLNNLQKLNNIQKLNNIQELNNSQELNNSQELNNSQELNNSQDLKNS 255 Q L+N + L+ L K +L+ +++L ++QE + L +ELN Q + Sbjct: 191 QNLSNNKNLSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKD 250 Query: 256 QVSCK 260 ++S K Sbjct: 251 KISIK 255
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 1e-04 Identities = 16/48 (33%), Positives = 19/48 (39%) Query: 27 PAIRGKGLAKKLALKAMEEAREMGFKRCYLETTAFLKEAIGLYEHLGF 74 R KG+ L KA+E A+E F LET A Y F Sbjct: 99 KDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 28.1 bits (62), Expect = 0.007 Identities = 15/39 (38%), Positives = 20/39 (51%), Gaps = 4/39 (10%) Query: 41 AGKDSAAIDKINAHYFDKKAEDYFFNKF-LLSFDPSTQQ 78 A D+AA+D AHY+ DY+ N LS+D S Sbjct: 292 ASYDAAAVD---AHYYAGVVYDYYKNVHGRLSYDGSNAA 327
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 58.0 bits (140), Expect = 4e-12 Identities = 36/136 (26%), Positives = 53/136 (38%), Gaps = 28/136 (20%) Query: 95 SPDVLFGLGSTELKPKFKLILDDFFPRYLKVLDNYQEHITEVRIEGHTSTDWTGTTNPDI 154 DVLF LKP+ + LD + L N V + G+ TD G+ Sbjct: 218 KSDVLFNFNKATLKPEGQAALD----QLYSQLSNLDPKDGSVVVLGY--TDRIGSD---- 267 Query: 155 AYFNNMALSQGRTRAVLQYVYDIKNIATHQQWVKSKFAAVGYSSAHPILDKTGKEDPNRS 214 AY N LS+ R ++V+ Y+ K I K +A G ++P+ T R+ Sbjct: 268 AY--NQGLSERRAQSVVDYLI-SKGIP------ADKISARGMGESNPVTGNTCDNVKQRA 318 Query: 215 ---------RRVTFKV 221 RRV +V Sbjct: 319 ALIDCLAPDRRVEIEV 334
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.008 Identities = 18/134 (13%), Positives = 50/134 (37%), Gaps = 13/134 (9%) Query: 161 AQIKLLRTEISDSSQAQLANHTHFSNKLWEQLEQFADLMAKGATEQI-IDALRQVIIDFN 219 + R E + A++ + + S +L+ F+ L+ K A + + ++ Sbjct: 207 LNLDKKRAER-LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAV 265 Query: 220 QNLTEQFGENFKALDASVKKLVEWQGNYKTQIEQMSEQYQQSV-ESLVETKTAVAGIWEE 278 L + L+ +++ K + + +++ ++ + + L +T + + E Sbjct: 266 NELRVYKSQ----LEQIESEILS----AKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 279 CK--EIPLAMSELR 290 E S +R Sbjct: 318 LAKNEERQQASVIR 331
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.030 Identities = 26/163 (15%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 334 RLASGAEEEAYRRLVESQFRDDDDEQAQSN---KGRLFKITLEKALFSSPMACASVVANR 390 + S E L++ QF +++ Q + + A + + V +R Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236 Query: 391 LKRLESRKDHN--SQSQINELESLLLALNNIDASQFSKYQLLLDTIRKDLAWKANNTEDR 448 L S ++ + E E+ + N S+ L+ I ++ + ++ Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQ----LEQIESEIL----SAKEE 288 Query: 449 LVIFTESIKTLEFLEQ--QLRADLKLKDDQIATLRGDQGDTVL 489 + T+ K E L++ Q ++ L ++A Q +V+ Sbjct: 289 YQLVTQLFKN-EILDKLRQTTDNIGLLTLELAKNEERQQASVI 330
>INTIMIN#Intimin signature. Length = 939 Score = 521 bits (1343), Expect = e-166 Identities = 157/528 (29%), Positives = 241/528 (45%), Gaps = 28/528 (5%) Query: 96 ENQIASTQFDFLHPWYDTPDYLLFSQHTLHRTDDRTQINTGLGWRHFTSSWMSGINLFFD 155 N + DFL P+YD+ L F Q D R N G G R F M G N+F D Sbjct: 220 GNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFID 279 Query: 156 HDLSRYHSRAGLGAEYWRDYLKLSSNAYIGLTGWRSAPELDNDFEARPANGWDLRAEGWL 215 D S ++R G+G EYWRDY K S N Y ++GW + D++ RPANG+D+R G+L Sbjct: 280 QDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRFNGYL 338 Query: 216 PAWPQLGGKLVYEQYYGDEVALFDKNDRQSNPHAITAGLNYTPFPLLTLSAEQRQGKQGE 275 P++P LG KL+YEQYYGD VALF+ + QSNP A T G+NYTP PL+T+ + R G E Sbjct: 339 PSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNE 398 Query: 276 NDTRFAVDLTWQPSSSMQKQLNPDEVAGRRSLAGSRYDLIDRNNNIVLEYRKKELIRLSL 335 ND +++ +Q +Q+ P V R+L+GSRYDL+ RNNNI+LEY+K++++ L++ Sbjct: 399 NDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI 458 Query: 336 LDPVKGKSGEIKPLVSSLQTKYALKGYNIEAAALEAAGGKVSTSG----KDITVTLPGYR 391 + G + + +++KY L + +AL + GG++ SG +D LP Y Sbjct: 459 PHDINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAY- 517 Query: 392 FTNTPETDNTWSIDVTAEDVKGNLSRHEQ-SMVVIQAPTLSQKDSLLSVNPLTVAADKKS 450 N + + A D GN S + ++ V+ + + + +A Sbjct: 518 ---VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADG 574 Query: 451 TTTLTVTAHDSD------GTPVPGLALQTRSEGVQDITLSDWTDNGDGSYTQILTAGTTS 504 T +T TA PV + G ++ + NG G T L + Sbjct: 575 TEAITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSANTNGSGKATVTLKSDKPG 630 Query: 505 GSVTLTPQINGESAVKESIVVNIVPVVSSRDHSSITIDNVSYYAGDDIKVRVELKDDSN- 563 V SA+ + V I + + I D + A + +K Sbjct: 631 QVVVSAKTAEMTSALNANAV--IFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGD 688 Query: 564 QPVAYQKEELVKAVTVENSKPGATIVWHEEQPGVYAANYPAYKQGTAL 611 +PV+ Q+ + K + + G + G +L Sbjct: 689 KPVSNQEVTFTTTL----GKLSNSTE-KTDTNGYAKVTLTSTTPGKSL 731 Score = 72.8 bits (178), Expect = 8e-15 Identities = 83/423 (19%), Positives = 137/423 (32%), Gaps = 41/423 (9%) Query: 868 VYGHPLPDEDVKFTLPASMTGNFTLSSETARTDANGDAVVTLRGTKAGEFTVTATLTRNN 927 + +D + LPA + G + TAR G + +T T+ N Sbjct: 500 QHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDR-------NGNSSNNVLLTITVLSNG 552 Query: 928 TVAYQQVTFIGDTNSAQLQPLTASLNSIVAGNSTGSTLTATILDAYQNPLKDQLV-TFQS 986 V Q + D TA S A + T TAT+ + S Sbjct: 553 QVVDQVG--VTD--------FTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVS 602 Query: 987 NDVTLSETEVTTNTLGQATVTMTSNIAGQHNVVVSRKAQASDNKTFSLSVLPDESSAKVI 1046 LS TN G+ATVT+ S+ GQ VV ++ A+ + + + D++ A + Sbjct: 603 GTAVLSANSANTNGSGKATVTLKSDKPGQ-VVVSAKTAEMTSALNANAVIFVDQTKASIT 661 Query: 1047 SITGAEKTITVGENITLRILVQDAFN-NVIAGQRVRLS-AQPTTNITIGDTAYTDNNGYA 1104 I + T + V+ ++ Q V + + + T TD NGYA Sbjct: 662 EIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNS---TEKTDTNGYA 718 Query: 1105 YVNLLSTQPGVYQVTATLDNNSSSKVDVNVAN-GKLELTSSKPETTVHNSEGITLTATAR 1163 V L ST PG V+A + + + V L + E +G T + Sbjct: 719 KVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQ 778 Query: 1164 NARGEL-MPGQIITFSVTPEGATLSNTGEVLTDQSGQAKVTLTSDKVNVYTVTAIMGKDV 1222 + L G ++ +N D S +VTL +V + Sbjct: 779 YGQVNLKASGGNGKYTW-----RSANPAIASVDAS-SGQVTLKEKGTTTISVIS------ 826 Query: 1223 PVQSQVTVAVKADAKTAHVVSVVASPDTITADGIDSSTITSRVEDDYGFPVEGVDISHGL 1282 T + +V + S D +++ +E V + G Sbjct: 827 --SDNQTATYTIATPNSLIVPNM-SKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGA 883 Query: 1283 DTK 1285 K Sbjct: 884 ANK 886 Score = 67.4 bits (164), Expect = 3e-13 Identities = 65/278 (23%), Positives = 105/278 (37%), Gaps = 21/278 (7%) Query: 1064 RILVQDAFNNVIAGQRVRLSAQPTTNITIGDTAYTDNNGYAYVNLLSTQPGVYQVTATLD 1123 RI+ D+ GQ +Q + AY N+ Y Sbjct: 484 RIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQ----GGSNVYKVTARAYDRNGNSS 539 Query: 1124 NNSSSKVDVNVANGKL-------ELTSSKPETTVHNSEGITLTATARNARGELMPGQIIT 1176 NN + V ++NG++ + T+ K +E IT TAT + G ++ Sbjct: 540 NNVLLTITV-LSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKK-NGVAQANVPVS 597 Query: 1177 FSVTPEGATLSNTGEVLTDQSGQAKVTLTSDKVNVYTVTA-IMGKDVPVQSQVTVAVKAD 1235 F++ A LS T+ SG+A VTL SDK V+A + + + V D Sbjct: 598 FNIVSGTAVLSANSAN-TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV--D 654 Query: 1236 AKTAHVVSVVASPDTITADGIDSSTITSRVEDDYGFPVEGVDISHGLDTKGSPVVNIPTT 1295 A + + A T A+G D+ T T +V PV +++ T + + T Sbjct: 655 QTKASITEIKADKTTAVANGQDAITYTVKV-MKGDKPVSNQEVT--FTTTLGKL-SNSTE 710 Query: 1296 RTDQSGQVTATITSTLAETLTVNVQVPGTANQSATITL 1333 +TD +G T+TST V+ +V A + Sbjct: 711 KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV 748 Score = 62.4 bits (151), Expect = 1e-11 Identities = 65/344 (18%), Positives = 112/344 (32%), Gaps = 26/344 (7%) Query: 744 LVADPDTIIAGNSQGSTLTAIITDFHNNPLKDMKVNFVAPGGSQLDNTTATTDQSGIVRV 803 AD + A ++ T TA + + G + L +A T+ SG V Sbjct: 563 FTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATV 622 Query: 804 HLTSSKAGSYSVDASLEVDKNIHQSVTITVVPNREQSVMTLNAGSGSAIANNTNIVTLTA 863 L S K G V A + + + V + S+ + A +A+AN + +T T Sbjct: 623 TLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTV 682 Query: 864 SVKDVYGHPLPDEDVKFTLPASMTGNFTLSSETARTDANGDAVVTLRGTKAGEFTVTATL 923 V P+ +++V FT N T +TD NG A VTL T G+ V+A + Sbjct: 683 KVMK-GDKPVSNQEVTFTTTLGKLSN-----STEKTDTNGYAKVTLTSTTPGKSLVSARV 736 Query: 924 TRNNT-VAYQQVTFIGDTNSAQLQPLTASLNSIVAGNSTGSTLTATI-LDAYQNPLKDQL 981 + V +V F + IV G T + Sbjct: 737 SDVAVDVKAPEVEFFTTLT------IDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGN 790 Query: 982 VTFQSNDVTLSETEVTTNTLGQATVTMTSNIAGQHNVVVSRKAQASDNKTFSLSVLPDES 1041 + + + + VT+ G + V +SDN+T + ++ Sbjct: 791 GKY---TWRSANPAIASVDASSGQVTL--KEKGTTTISVI----SSDNQTATYTI--ATP 839 Query: 1042 SAKVISITGAEKTITVGENI-TLRILVQDAFNNVIAGQRVRLSA 1084 ++ ++ T N + N + A Sbjct: 840 NSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGA 883 Score = 33.5 bits (76), Expect = 0.008 Identities = 44/314 (14%), Positives = 91/314 (28%), Gaps = 38/314 (12%) Query: 367 AALEAAGGKVSTSGKDITVTLPGYRFTNTPETDNTWSIDVTAEDVKGNLSRHEQSMVVIQ 426 A L A + SGK TVTL + V + S + V+ Sbjct: 605 AVLSANSANTNGSGK-ATVTL----------KSDKPGQVVVSAKTAEMTSALNANAVIF- 652 Query: 427 APTLSQKDSLLSVNPLTVAADKKSTTTLTVTAHDSDGTPVPGLALQTRSEGVQDITLSDW 486 + + + T A+ + T TV PV T + + ++ S Sbjct: 653 VDQTKASITEIKADKTTAVANGQDAITYTVKV-MKGDKPVSN-QEVTFTTTLGKLSNSTE 710 Query: 487 TDNGDGSYTQILTAGTTSGSVTLTPQINGESAVKESIVVNIVPVVSSRDHSSITIDNVSY 546 + +G LT TT G ++ +++ + ++ V ++ Sbjct: 711 KTDTNGYAKVTLT-STTPGKSLVSARVSDVAVDVKAPEVEFFTTLTI------------- 756 Query: 547 YAGDDIKVRVELKD-DSNQPVAYQKEELVKAVTVENSKPGATIVWHEEQPGVYAANYPAY 605 DD + + P + + V + W P + + + + Sbjct: 757 ---DDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGN---GKYTWRSANPAIASVDASSG 810 Query: 606 KQGTALRAQLSLHNWNAPLQSHIYNIEANQNKARVATLSATNNDVYADKKTFNTLTINVT 665 + + ++ ++ Q+ Y I + + + + Y D Sbjct: 811 QVTLKEKGTTTISVISSDNQTATYTIATPNS---LIVPNMSKRVTYNDAVNTCKNFGGKL 867 Query: 666 DESDNPLTNHQVTF 679 S N L N + Sbjct: 868 PSSQNELENVFKAW 881
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 28.6 bits (64), Expect = 0.040 Identities = 64/316 (20%), Positives = 113/316 (35%), Gaps = 24/316 (7%) Query: 82 RPFLLASALATGLLILAMAWLPPFLLVFIIRFLAGV-----ASAGMLIFGSTLIMQHTRH 136 RP LL S + MA P +++I R +AG+ A AG I T + RH Sbjct: 73 RPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARH 132 Query: 137 PFVLAALFSGVGVGIALGNEYVLAGLHFALSSQTLWQGAGALSAIILLALALLIP-SNKH 195 ++A F G G+ G VL GL S + A AL+ + L L+P S+K Sbjct: 133 FGFMSACF---GFGMVAGP--VLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 196 VIPPAPLAKIAQQPMSWW---------LLAILYGLAGFGYIIVATYLPLMAKDAGQPVLT 246 P + W L+A+ + + G + A ++ + +D T Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV-IFGEDRFHWDAT 246 Query: 247 AHLWTLVGLSIVPGCFGWLWA---AKRWGALPCLTANLLVQAICVLLTLASSSPLLLIIS 303 +L I+ + A R G L ++ +L ++ + Sbjct: 247 TIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPI 306 Query: 304 SIGFGGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLGNGTSALA 363 + +G +L ++RQ+ L G + + + I+GP L + + + Sbjct: 307 MVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTW 366 Query: 364 SATLCGAAALFIAALI 379 + A A + Sbjct: 367 NGWAWIAGAALYLLCL 382
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 51.8 bits (124), Expect = 3e-09 Identities = 47/189 (24%), Positives = 76/189 (40%), Gaps = 5/189 (2%) Query: 7 RHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGMALQW 66 RH L + L + + ++ P I N A + A L + G A+ Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV-- 68 Query: 67 LLGPLSDRIGRKPVLITGALIFTLACAATMFTTSMTQFLI-ARAIQGTSICFIATVGYVT 125 G LSD++G K +L+ G +I S LI AR IQG + V Sbjct: 69 -YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 126 VQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFVHWKVLFAIIAVMGFISFVGLL 185 V + K +I SIV + +GP G + H++HW L +I ++ I+ L+ Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL-LIPMITIITVPFLM 186 Query: 186 LAMPETVKR 194 + + V+ Sbjct: 187 KLLKKEVRI 195
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.004 Identities = 20/91 (21%), Positives = 29/91 (31%), Gaps = 15/91 (16%) Query: 34 MVTLLGPSGCGKTTILRLVAGLEKPSEGQIFIDGEDVTHRSI-QQRDICMVFQSYALFPH 92 V L G G GK+T++ + GL F D TH I +D Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL------DFFSD----THFDIGTGKDSYEQIAGIVA--- 644 Query: 93 MSLGENVGYGDEPLSNLDANLRRSMRDKIRE 123 L E + + A +D+ R Sbjct: 645 YELSEMTAFRRADAEAVKAFFSSR-KDRYRG 674
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.8 bits (67), Expect = 0.015 Identities = 17/69 (24%), Positives = 29/69 (42%), Gaps = 10/69 (14%) Query: 187 FISGTGFATDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 245 +G ++D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 246 DVIVLGGGM 254 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.4 bits (123), Expect = 3e-09 Identities = 74/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%) Query: 5 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 61 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 62 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 121 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 122 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 181 G A G +S ++ P+ L FS F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 182 RDEAKGKLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 229 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 230 SGFSETAMTFIMMLVGLGM---VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCG 286 F A T + L G+ + M++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 287 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 340 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.4 bits (92), Expect = 7e-05 Identities = 34/199 (17%), Positives = 71/199 (35%), Gaps = 14/199 (7%) Query: 671 QQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDDLPHSEETVALDNWRQVHEQCLALH 730 + + Q + Q R Q L+ +E + E + +V + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTAL--------QASVFDDQQAFLAALMDEQTLTQL 782 Q T Q Q +L K +A+ T L + V + ++L+ +Q + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA-- 250 Query: 783 EQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDGLALTVTVEQIQQEL-AQTHQKLREN 841 K + Q + V + +Q +Q + L+ + + Q + KLR+ Sbjct: 251 ---KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQT 307 Query: 842 TTSQGEIRQQLKQDADNRQ 860 T + G + +L ++ + +Q Sbjct: 308 TDNIGLLTLELAKNEERQQ 326 Score = 39.4 bits (92), Expect = 7e-05 Identities = 25/204 (12%), Positives = 59/204 (28%), Gaps = 18/204 (8%) Query: 487 EARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 EA ++ Q + Q ++E + E + +E + L Sbjct: 133 EADTLKTQSSLLQARLEQ---TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT- 188 Query: 547 AALRGQLDALTKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQD 606 + ++ Q Q + E R + + + + DD L Q Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 607 -------EHERQL-RLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLP 658 E E + +++ + Q+ +I+ +++ + Q L Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF------KNEILD 302 Query: 659 QEDEEESWLATRQQEAQSWQQRQN 682 + + + E ++RQ Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQ 326 Score = 33.3 bits (76), Expect = 0.006 Identities = 16/150 (10%), Positives = 42/150 (28%), Gaps = 5/150 (3%) Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTA----LQASVFDDQQAFLAALMDEQTLTQLEQLK 786 + Q + A + Q + L D+ F +E+ L +K Sbjct: 134 ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVS-EEEVLRLTSLIK 192 Query: 787 QNLENQRRQAQTLVTQTAETLAQHQQHRPDGLALTVTVEQIQQELAQTHQKLRENTTSQG 846 + + Q + A+ + L L + ++ Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 847 EIRQQLKQDADNRQQQQTLLQQIAQMTQQV 876 + +Q + + + + Q+ Q+ ++ Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEI 282
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.022 Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%) Query: 62 KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 +F +P++ + F RR LL + V A M W+ + ++A + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181 + V A+ D+ +ER + GM+ L + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 AL + + L PE + P+ + + + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 A +L F +DA +G+ G+L ++ A+ G + RL RAL+ G++ Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285 Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358 A GY LL+ + + V GG+G A A+L ++ L+ Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLVCR 403 AL+++ + VGP+ + A +T+ + + AA+ L L + R Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.029 Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 3 KKILFPLVALFMLAGCARPPTTIEVSPTITLPQQ 36 KK+LF ++ GCA+ T+ PT P++ Sbjct: 7 KKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.043 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%) Query: 60 ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119 E P+ E + ++G+ A + +Y RL D +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.5 bits (76), Expect = 0.003 Identities = 23/101 (22%), Positives = 48/101 (47%), Gaps = 7/101 (6%) Query: 195 KQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQK 254 ++ + L A QV R +++ ++ S+ +Q++A + Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAK---KQLEAEHQ 333 Query: 255 ELGEMDDAPD-ENEALKRKIDAAKMPKEAKEKAEAELQKLK 294 +L E + + ++L+R +DA++ EAK++ EAE QKL+ Sbjct: 334 KLEEQNKISEASRQSLRRDLDASR---EAKKQLEAEHQKLE 371
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 3e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 27.5 bits (61), Expect = 0.018 Identities = 24/138 (17%), Positives = 41/138 (29%), Gaps = 20/138 (14%) Query: 1 MQTQIKVRGYHLDVYQHVNNARYL-------EFLEEARWDGLENSDSFHWMTAH------ 47 +Q I + Y N Y E++ + N FH + Sbjct: 361 LQHFIPETNLFVSPYYKGNQKLYTSLKLIVEEWMAKLPGKRYLNHKHFHLFCHYVEQILR 420 Query: 48 ------NIAFVVVN-ININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVA 100 + FV N IN + + + + Q+ L+P+ + Sbjct: 421 NIQPPLVVVFVASNFINAHLLTDSFPRYFSDKSIDFHSYYLLQDNVYQIPDLKPDLVITH 480 Query: 101 DALITFVCIDLKTQKALA 118 LI FV +L A+A Sbjct: 481 SQLIPFVHHELTKGIAVA 498
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 12/64 (18%), Positives = 24/64 (37%), Gaps = 10/64 (15%) Query: 197 LTVLTQHLGLSLRDCMAFGDAMNDREMLGSVGSGFIMGN----------AMPQLRAELPH 246 TVL Q L + D +A + + ++ + +P+++ P Sbjct: 16 RTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPD 75 Query: 247 LPVI 250 LPV+ Sbjct: 76 LPVL 79
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.8 bits (67), Expect = 0.028 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 24/137 (17%) Query: 247 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 306 W+ L L+ G +A +LR R+ + + P++ G+I Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272 Query: 307 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSVFEDMGDWLRQHPQQHISINLE 365 AR+ +T + S +PL Q +S + ++ R D +R+ H + LE Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328 Query: 366 STVLTSEKIPQLLREMI 382 T L P ++R MI Sbjct: 329 QTAL----FPPMMRHMI 341
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3545), Expect = 0.0 Identities = 801/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSIEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+S+EKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 6e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 100 TYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 159 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 8e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 49 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDS 107 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 167 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 168 RINLA 172 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 221 bits (564), Expect = 1e-75 Identities = 214/215 (99%), Positives = 214/215 (99%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPSDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFP DPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 257 bits (657), Expect = 1e-83 Identities = 103/434 (23%), Positives = 168/434 (38%), Gaps = 56/434 (12%) Query: 11 LTEPRLPRSALAV-RVTAVMLLCFLGWAWYFQLDEVTTGSGTVEPSGREQVVQSLEGGIL 69 L E + R V L+ + Q++ V T +G + SGR + ++ +E I+ Sbjct: 48 LIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIV 107 Query: 70 YHLDVKVGDIVEQGQPLAQLNRTKTESDVQEAMSRLYAALATSARLRAEVSNK------P 123 + VK G+ V +G L +L E+D + S L A R + + Sbjct: 108 KEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPE 167 Query: 124 LVFPDEL----------------------NKFPELIESETALYNTR--RDGLNKATTGLT 159 L PDE + + E L R R + Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 160 QGISLVNRELAMTQPLVKQGAASSVEVLRLQRQANELEN--------------------- 198 + L L+ + A + VL + + E N Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287 Query: 199 KLSDVRTQYYVQAREELAKANAEVETQRSVIRGREDSLTRLNFTAPVRGIVQDIDVTTVG 258 + V + + ++L + + + E+ APV VQ + V T G Sbjct: 288 EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEG 347 Query: 259 GVIAPGGKLMTIVPLDEQLLIEAKISPRDVAFIHPGQKSLVKITAYDYSIYGGLPGEVAV 318 GV+ LM IVP D+ L + A + +D+ FI+ GQ +++K+ A+ Y+ YG L G+V Sbjct: 348 GVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKN 407 Query: 319 ISPDTVQDEVRRDVYYYRVYIRTFSNHLENKSKQQFPIFPGMVATVDIRTGKKSVLDYLL 378 I+ D ++D+ R + V I N L +K P+ GM T +I+TG +SV+ YLL Sbjct: 408 INLDAIEDQ--RLGLVFNVIISIEENCLSTGNK-NIPLSSGMAVTAEIKTGMRSVISYLL 464 Query: 379 KPF-NKAQEALRER 391 P E+LRER Sbjct: 465 SPLEESVTESLRER 478
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 55.2 bits (133), Expect = 3e-12 Identities = 21/78 (26%), Positives = 34/78 (43%), Gaps = 1/78 (1%) Query: 262 RKEANAGTASAIAIASQPQVKTGDVMMVSAGAGTFNGESAVSVGTSFNAGTHTVLKAGIS 321 KE G A+ A++ Q VSA G + ++A+++G KAG++ Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 322 ADTQS-DFGAGVGVGYSF 338 +T + G VGY F Sbjct: 62 FNTYNGGMSYGASVGYEF 79
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.018 Identities = 30/183 (16%), Positives = 67/183 (36%), Gaps = 34/183 (18%) Query: 306 EELTRMAKMVSDML-FLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDR-GVELQFV 363 + M +S+++ + + N + + LADE+ V + + LA + LQF Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVS------LADELTVVDSYLQ-LASIQFEDRLQFE 243 Query: 364 GDECQVAGDPLMLRRALSNLLSNALRY----TPPGEAIVVRCQTVDHLVQVIVENPGTPI 419 D + + L+ N +++ P G I+++ + V + VEN G+ Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 420 APEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVK---SIVVAHKGTVAVTSNARGTRFVI 476 E +G GL V+ ++ + + ++ ++ Sbjct: 304 LKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 477 VLP 479 ++P Sbjct: 346 LIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 9e-05 Identities = 24/182 (13%), Positives = 59/182 (32%), Gaps = 13/182 (7%) Query: 254 QAQTVNSDSLQSVKLPA-GLSSQILLQRPDIMEAEHALM-----AANANIGAARAAFFPS 307 + +S + +K + +I+++ + + L+ A A+ ++ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS----- 141 Query: 308 ISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYE 367 SL + + + + P F + L + + ++Q Sbjct: 142 -SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 368 QKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAER 427 QK Q + A R ++ +I+ + + L +L A++ VL+ E Sbjct: 201 QKYQ-KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 428 SL 429 Sbjct: 260 KY 261
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 694 bits (1793), Expect = 0.0 Identities = 213/1058 (20%), Positives = 439/1058 (41%), Gaps = 54/1058 (5%) Query: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V + +YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAELGP-DATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVA 178 LP V + + + ++ V + D+ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELA------EAEYMVR 232 G ++ +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFNHIVLKASENGVPVYLRDVAKIQVGPEMRRGIAELNG-EVVGGVVILRS 291 A + ++F + L+ + +G V L+DVA++++G E IA +NG G + L + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLAT 295 Query: 292 GKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVVC 351 G NA + A+K KL L+ P+G++++ YD + + +I + L E ++V +V Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 352 ALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIEN 411 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++EN Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 412 AHKRLEEWQHQHPDATLDNKTRWQVITNASVEVGPALFISLLIITLSFIPIFTLEGQEGR 471 + + E D + + ++ AL ++++ FIP+ G G Sbjct: 416 VERVMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGA 465 Query: 472 LFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRF----------LIR 521 ++ + T AMA + L+A+++ P L ++ + E F + Sbjct: 466 IYRQFSITIVSAMALSVLVALILTPALCATLLKP-VSAEHHENKGGFFGWFNTTFDHSVN 524 Query: 522 VYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISAA 581 Y + K+L LL+ AL V ++ ++ FLP+ ++G L M G + Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584 Query: 582 EAASMLQKTDKLIM--SVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQW-RPGM 638 +L + + V VF G + + + LKP E+ Sbjct: 585 RTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDEN 641 Query: 639 TMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADI-DAMAEQ 697 + + +I + + + +++ + I +G + A + Sbjct: 642 SAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 698 IEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGET 757 + A+ + S LE +E+++EKA G++++D+ +++A+GG V + Sbjct: 702 LGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF 761 Query: 758 VEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADVKVSTGPSMLKTENAR 817 ++ + ++ +R P+ + +L + + + + + G L+ N Sbjct: 762 IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGL 821 Query: 818 PTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPMT 877 P+ I +A L + +A K L G ++G + ++ +V ++ Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAIS 879 Query: 878 LMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAAE 937 +++F+ L + + ++ VP +VG + V G + G++A+ Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 938 FGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEALHHGAVLRVRPKAMTVAVIIAGLLPIL 997 ++++ + + +E E + + EA +R+RP MT I G+LP+ Sbjct: 940 NAILIVEFAKDLMEKE----------GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 998 WGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1035 GAGS + + ++GGM++A LL++F +P + + Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 45.6 bits (108), Expect = 5e-10 Identities = 14/53 (26%), Positives = 23/53 (43%), Gaps = 5/53 (9%) Query: 1 MVGENGHAWLSGVDENQQFTVHWG--DQKTCAIH--LPEHLEDVT-KRLILPC 48 +V +NG +LSG+ + V WG + C + LP + +L C Sbjct: 825 IVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAEC 877
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 548 bits (1414), Expect = 0.0 Identities = 208/760 (27%), Positives = 338/760 (44%), Gaps = 57/760 (7%) Query: 5 RLSVLSCLAMVTPPALTA-EFNLNVLDKSIRDSVDISLLNQKGVVAPGDYFVSVTVNNNK 63 RL V A P + FN L + D+S + PG Y V + +NN Sbjct: 29 RLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88 Query: 64 ISNGQQIRWQKSGDK--IIPCINESLIELFGLKSDFRKKLPAIKE--CVDF-SVFPEIIF 118 ++ + + + + I+PC+ + + GL + + + + CV S+ + Sbjct: 89 MAT-RDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATA 147 Query: 119 TFDQANQQLNITIPQAWLAWHSENWTPPSTWNNGIPGFLMDYNLFASTYRPQSGSSSNNL 178 D Q+LN+TIPQA+++ + + PP W+ GI L++YN ++ + + G +S+ Sbjct: 148 QLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYA 207 Query: 179 NAYGTTGLNAGAWRLRSDYQLSQSDSGDNREQSGAI--SRTYLFRPLPQIGSRLTLGETD 236 +GLN GAWRLR + S + S + T+L R + + SRLTLG+ Sbjct: 208 YLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGY 267 Query: 237 FSSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGIAQTNATVTISHSGRVIYQKKVPP 296 +IFDG ++ GA LASDD MLP RG+AP I GIA+ A VTI +G IY VPP Sbjct: 268 TQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPP 327 Query: 297 GPFIIDDLNQ-SVQGTLDVKVSEEDGRVNNFQVSAASTPFLTRQGQVRYKLAAGRPRSSM 355 GPF I+D+ G L V + E DG F V +S P L R+G RY + AG RS Sbjct: 328 GPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSG- 386 Query: 356 SHHTEDETFISHEVSWGMLSNTSLYGGMLLAGDDYRSGALGIGQNMLWMGALSFDVTWAD 415 + E F + G+ + ++YGG LA D YR+ GIG+NM +GALS D+T A+ Sbjct: 387 NAQQEKPRFFQSTLLHGLPAGWTIYGGTQLA-DRYRAFNFGIGKNMGALGALSVDMTQAN 445 Query: 416 SHFDTQQDEQGYSYRFNYSKQVDATNSTISLAAYRFSDRHFHSYANYIDHKYNDADAQDE 475 S G S RF Y+K ++ + + I L YR+S + ++A+ + N + + + Sbjct: 446 STLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQ 505 Query: 476 --------------------KQTISLSFGQPITLLNLNLYANILHQSWWNADTSTTANIT 515 + + L+ Q + + LY + HQ++W Sbjct: 506 DGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS-TLYLSGSHQTYWGTSNVDE-QFQ 563 Query: 516 VGFNVDIGDWKDISVSTSFNTTHYE-DKDRDNQIYFSISLPIG-----------ESGRLG 563 G N ++DI+ + S++ T K RD + ++++P Sbjct: 564 AGLNT---AFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASAS 620 Query: 564 YDMQNNSN-TTTHRMSWNDTLDERN--SWGMSAG-IQSDRPDNGAQVSGNYQHLSSAGEW 619 Y M ++ N T+ TL E N S+ + G ++G+ + G Sbjct: 621 YSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNA 680 Query: 620 DLTGTYAANDYTSASASWSGSFTATQHGAAFHRRSSTNEPRLMVSTDGVGDIPIQGN-ID 678 ++ G ++D SG A +G + N+ ++V G D ++ Sbjct: 681 NI-GYSHSDDIKQLYYGVSGGVLAHANGVTLGQP--LNDTVVLVKAPGAKDAKVENQTGV 737 Query: 679 YTNRFGIAVVPFVSSYQPTTVAVNMNDLPDGVTVSENVVK 718 T+ G AV+P+ + Y+ VA++ N L D V + V Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVAN 777
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 33.5 bits (76), Expect = 2e-04 Identities = 41/179 (22%), Positives = 79/179 (44%), Gaps = 26/179 (14%) Query: 14 SLLFASPVFAADEGSGEIHFKGEVIEAPCEIHPDDLDMNIDLGEVTTSHINREHHSEKK- 72 ++L + V AAD + FKG++I C + + ++ G++ ++ + ++K Sbjct: 15 AVLMSQHVHAADN----LTFKGKLIIPACTVQ----NAEVNWGDIEIQNLVQSGGNQKDF 66 Query: 73 PVNIRLINCDIAGWDDGKGGVVSKVGVTFDSTAKTTGATPLLSNISAGEATGVGVRLMNK 132 V++ NC + + + VT S TG + L+ N S G+ + L N Sbjct: 67 TVDM---NCPYS---------LGTMKVTITSNG-QTGNSILVPNTSTASGDGLLIYLYNS 113 Query: 133 DES----FVTLGTEAPTIDLLASSTEQTLNFFAWMEQMDNAVSVTAGAVTANATYVLDY 187 + S VTLG++ + ++ + + +A + N S+ AG +A AT V Y Sbjct: 114 NNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASY 172
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 29.7 bits (66), Expect = 0.010 Identities = 19/63 (30%), Positives = 28/63 (44%), Gaps = 7/63 (11%) Query: 193 LMSTHHPLHANAIADSIIQVEPDGRVTQGLPTEQLTTNKLAAL------YRVSADQIHHH 246 + H L A+ I D I++V D G +L +LA L Y V +I+ H Sbjct: 119 MAVMHFSLTADRIDDDILKVIVDSMNHHGDARSKL-REELAELTAELKIYSVIQAEINKH 177 Query: 247 LSA 249 LS+ Sbjct: 178 LSS 180
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.6 bits (63), Expect = 0.044 Identities = 21/51 (41%), Positives = 29/51 (56%), Gaps = 2/51 (3%) Query: 55 LLLAVAPEKMVGFSSFDFARQALIPLSEHIRQLPRLGRLAGRASTLSLEGL 105 L + VA E + + F +QAL P+ EH+ L L L G+A T +LEGL Sbjct: 348 LAVMVADEIVKAATGVSFIQQALNPIMEHV--LKPLMELIGKAITKALEGL 396
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 141 bits (357), Expect = 1e-38 Identities = 63/206 (30%), Positives = 102/206 (49%), Gaps = 1/206 (0%) Query: 259 GKAFYYQPVLCTVQAKSPLTVEEEQERLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSG 318 KAF + ++ S V E E+L A++ + +L + + EAS D A IF+ Sbjct: 17 AKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAA 76 Query: 319 HHTLLDDPELLAAASELLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLH 378 H +LDDPEL+ +++E AEYA ++V ++ +D+EY++ R D+ D+ Sbjct: 77 HLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMKERAADIRDVSK 136 Query: 379 RTLVHLT-QTKEELPQFNSPTILLAENIYPSPVLQLDPAVVKGICLSAGSPVSHSALIAR 437 R L HL L T+++AE++ PS QL+ VKG G SHSA+++R Sbjct: 137 RVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSR 196 Query: 438 ELGIGWICQQGEKLYAIQPEEKLTLD 463 L I + E IQ + + +D Sbjct: 197 SLEIPAVVGTKEVTEKIQHGDMVIVD 222
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.6 bits (71), Expect = 0.002 Identities = 10/47 (21%), Positives = 25/47 (53%) Query: 138 VESLRQSSEQNLSVPAALEAASSIAEFAAQSTITMQARKGRASYLGE 184 E++ + ++N + +EA ++A A + + A+ G+A+ G+ Sbjct: 293 REAVDRWIQENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGD 339
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 43.5 bits (102), Expect = 2e-06 Identities = 117/548 (21%), Positives = 198/548 (36%), Gaps = 92/548 (16%) Query: 14 RLAELKIRSPSIQLIKFGAIGLNAILFSPLLIAADTGSQYGTNITINDGDRI---TGDTA 70 + A L+ + ++ L GA ++ I Q+G +I +D + +G T Sbjct: 10 KAAPLRRTTLAMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTI 69 Query: 71 DPSGN-LYGVMTPAGNTPGNINLGNDVTVN---VNDASGYAKGIIIQGKNSSLTANRLTV 126 SG G++ N + N + ++D + K L A+ T+ Sbjct: 70 KVSGRQAQGILLE--NPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATL 127 Query: 127 DVVGQT---SAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIG 183 VG T I + + G+ A + ST++ G+ I + +T + I + G+ Sbjct: 128 ANVGDTWDDDGIALYVAGEQAQASIAD-STLQGAG-GVQIERGANVTVQRSAIVD-GGLH 184 Query: 184 LTINDYGTSVDLGSGSKIKTDGS-TGVYIGGLNGNNANGAARFTATDLTID---VQGYSA 239 + DL + D + T V G + A++LT+D + G A Sbjct: 185 IGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPA----AVSVLGASELTLDGGHITGGRA 240 Query: 240 MGINVQKNSVVDLGTNSSIKTSGDNAHGLWSFGQVSANAL-------TVDVTGAAANGVE 292 G+ + +VV L ++I+ A G G V A+ GV+ Sbjct: 241 AGVAAMQGAVVHL-QRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVD 299 Query: 293 VRGGTTTIGADSHISSAQGGGLVTSGSDATINFSG---TAAQRNSIFSGGSYGASAQTAT 349 V G + + A S + + + G + G A + SG +A N I +GG+ + Q A Sbjct: 300 VSGSSVEL-AQSIVEAPELGAAIRVGRGARVTVSGGSLSAPHGNVIETGGARRFAPQAAP 358 Query: 350 AVINMQNTDITVDRNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDL 409 I +Q G+ A G L L +TG A A+G T + + Sbjct: 359 LSITLQA--------GAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTSI 410 Query: 410 VIDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLS 469 P +A+A+ + WTG++ Sbjct: 411 -----GPLDVALAS------------------------------------QARWTGAT-- 427 Query: 470 DNVNGGKLDVAMNNSVWNVTSNSNLDTLAL-SHSTVDFASHGSTAGTFTTLNVENLSGNS 528 V+ +D N+ W +T NSN+ L L S +VDF + AG F L V L+G+ Sbjct: 428 RAVDSLSID----NATWVMTDNSNVGALRLASDGSVDFQQ-PAEAGRFKVLTVNTLAGSG 482 Query: 529 TFIMRADV 536 F M Sbjct: 483 LFRMNVFA 490
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 33.0 bits (75), Expect = 0.003 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 16/81 (19%) Query: 279 LGAIESLLCAV----VL---DGMTGTKHKANSELVGQGLGNI---IAPFF------GGIT 322 L + +L A+ +L D T TK A EL + LGN+ I+ + G++ Sbjct: 242 LDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLS 301 Query: 323 ATAAIARSAANVRAGATSPIS 343 +AA A A+ A SP+S Sbjct: 302 TSAAAAGLIASAVTLAISPLS 322
>INTIMIN#Intimin signature. Length = 939 Score = 258 bits (660), Expect = 8e-80 Identities = 120/378 (31%), Positives = 196/378 (51%), Gaps = 21/378 (5%) Query: 32 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 91 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 92 DRYLTWSQLGLTQQDDGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWG 151 ++ L + Q+G D +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 152 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDR 209 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 210 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 269 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 270 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 329 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 330 RSRYGIRQLIWQGDTQILS-----LTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVV 384 +S+YG+ +++W D+ + S G+Q SA+ + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 385 EDNQGQRVSSNEITLTLV 402 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.2 bits (68), Expect = 0.015 Identities = 17/58 (29%), Positives = 29/58 (50%), Gaps = 1/58 (1%) Query: 128 TPYSVFIIISLLCGFAGANF-ASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLV 184 + +S+ I+ + G A F A M ++ + PK+ +G A GL G + MG V + Sbjct: 101 SFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI 158
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.007 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGKSLIAKAI 53 + GESG+GK L+A+A+ Sbjct: 165 ITGESGTGKELVARAL 180
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 62.2 bits (151), Expect = 2e-13 Identities = 41/192 (21%), Positives = 82/192 (42%), Gaps = 19/192 (9%) Query: 6 LSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTITQLTLTASLIGLGVGQLLFGPL 65 L W IL + + +LP+++ T TA ++ +G ++G L Sbjct: 16 LIWLCILSFF---SVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKL 72 Query: 66 SDKIGRKRPLILSLLLFIVSSILCATTNNIY-WLVVWRFIQGIAGAG-----GSVLSRSI 119 SD++G KR L+ +++ S++ ++ + L++ RFIQG A V++R I Sbjct: 73 SDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYI 132 Query: 120 ARDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDWRTLFWVMAEISTVLLLGCV 179 ++ F L+ ++ + + P +GG I W L + ++ + V Sbjct: 133 PKENRGKA-----FGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP-----MITIITV 182 Query: 180 LFINETLPENKR 191 F+ + L + R Sbjct: 183 PFLMKLLKKEVR 194
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.5 bits (74), Expect = 0.002 Identities = 26/166 (15%), Positives = 49/166 (29%), Gaps = 11/166 (6%) Query: 70 DVQKAIADIDSARALYGQTNASLFPTVNAALSSTRSRSLANGTETTAEADGTVSSFTLDL 129 A AD ++ Q +RS L E + + + + Sbjct: 128 TALGAEADTLKTQSSLLQARL----EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEE 183 Query: 130 FGRNQSLSRAARETWLASEFTAQNTRLTLIAEISTAWLTLAADNSNLALAKETMTSAENS 189 R SL + TW ++ + AE T + + + K Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS-------R 236 Query: 190 LKIIQRQQQVGTAAATDVSEAMSVYQQARASVASYQTQVMQDKNAL 235 L A V E + Y +A + Y++Q+ Q ++ + Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 62.2 bits (151), Expect = 1e-15 Identities = 27/49 (55%), Positives = 42/49 (85%) Query: 1 MPLAIATGSGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAG 49 +PLAI+ G+G+ ++ A+G G++GG ++ATLLAIFFVP+FFV+++R F G Sbjct: 986 LPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFKG 1034
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1105 bits (2860), Expect = 0.0 Identities = 550/983 (55%), Positives = 713/983 (72%), Gaps = 8/983 (0%) Query: 3 SRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISATYTGASAETLENSV 62 + FF+RRP+FAWV+AI++M+AG LAI LPVAQYP +APP + +SA Y GA A+T++++V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 63 TQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPDTAQ--VQNKIQQAESRLPSE 120 TQVIEQ + G+DNL+Y SSTS S GSV+I +TF+ GTDPD AQ VQNK+Q A LP E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 121 VQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGSLQVFGAE 180 VQQ G++VEKS S++L++A + DI+D++ SNV+D L+R+ GVG +Q+FGA+ Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ 181 Query: 181 YAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQLTATVRAQSRLQ 240 YAMRIWLD L Y L P DV + ++ QN Q+ AG++G P+ QQL A++ AQ+R + Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 241 TVDQFKNIIVKSQSDSAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVAVMLSPGANALN 300 ++F + ++ SD +VVR+KDVARVE+G E+Y I ++NG P+AG+ + L+ GANAL+ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 301 TATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVLVVCVMYLFLQN 360 TA +K K+AE Q PQG + YP D+T F+++S+ +V++TLFEAI+LV VMYLFLQN Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 361 LRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAIVVVENVERIMR 420 +RATLIP +AVPVVLLGTF +LA FGYSINTLT+F MVLAIGLLVDDAIVVVENVER+M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 421 DKGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQFSITIISAMLLS 480 + LP +EATEKSM +I GALV IA+VLSAVF+PMAFFGGSTG IYRQFSITI+SAM LS Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 481 VVVALTLTPALCGSVL----QHVPPHKKGFFGAFDRFYRRTEDKYQRGVIYVLRRAARTM 536 V+VAL LTPALC ++L +K GFFG F+ + + + Y V +L R + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 537 GLYLVLGGGMALMMWKLPGSFLPTEDQGEIMVQYTLPAGATAARTAEVNRQIVDWFLINE 596 +Y ++ GM ++ +LP SFLP EDQG + LPAGAT RT +V Q+ D++L NE Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 597 KANTDVIFTVDGFSFSGSGQNTGMAFVSLKNWSQRKGAENTAQAIALRATKELGTIRDAT 656 KAN + +FTV+GFSFSG QN GMAFVSLK W +R G EN+A+A+ RA ELG IRD Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 657 VFAMTPPAVDGLGQSNGFTFELLANGGTDRETLLQMRNQLIEKANQSP-ELHSVRANDLP 715 V PA+ LG + GF FEL+ G + L Q RNQL+ A Q P L SVR N L Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 716 QMPQLQVDIDSNKAVSLGLSLNDVTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSA 775 Q ++++D KA +LG+SL+D+ T+S+A GGTYVNDFIDRGRVKK+Y+Q D++FR Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 776 PSDLGKWFVRGSDNAMTPFSAFATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMT 835 P D+ K +VR ++ M PFSAF T+ W+YG RL RYNG + EIQGE A G SSGDAM Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 836 KMEELANSLPAGTTWAWSGLSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVI 895 ME LA+ LPAG + W+G+S QE+L+ QA +L A+S +VVFLCLAALYESWS+P SV+ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 896 LVIPLGLLGAALAAWMRDLNNDVYFQVALLTTIGLSSKNAILIVEFA-EAAVAEGYSLSR 954 LV+PLG++G LAA + + NDVYF V LLTTIGLS+KNAILIVEFA + EG + Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 955 AALRAAQTRLRPIIMTSLAFIAG 977 A L A + RLRPI+MTSLAFI G Sbjct: 962 ATLMAVRMRLRPILMTSLAFILG 984 Score = 89.9 bits (223), Expect = 3e-20 Identities = 76/502 (15%), Positives = 164/502 (32%), Gaps = 26/502 (5%) Query: 6 FVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTIKISA-TYTGASAETLENSVTQ 64 + +I LI+ ++ LP + P+ GA+ E + + Q Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 65 VIEQQLTGLDNLLY-------FSSTSSSDGSVSINVTFEQGTDPDTAQ--VQNKIQQAES 115 V + L + FS + + + V+ + + + + + I +A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 116 RLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLVSNVQDPLARVEGVGS-- 173 L + L A +D + D L L + Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 174 ----LQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAGKIGALPSPNTQQL 229 ++ +D K + + SD+ I + ++L Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF--IDRGRVKKL 770 Query: 230 TATVRAQSRLQTVDQFKNIIVKSQSDSAVVRIKDVARVEMGSEDYTAIGKLNGHPSAGVA 289 A+ R + + V+S ++ +V + + NG PS + Sbjct: 771 YVQADAKFR-MLPEDVDKLYVRS-ANGEMVPFSAFTTSHWV-YGSPRLERYNGLPSMEIQ 827 Query: 290 VMLSPGANALNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFIKISVEDVIQTLFEAIVL 349 +PG + A + + +A +P G + S + S + + V+ Sbjct: 828 GEAAPGTS-SGDAMALMENLAS---KLPAGIGYDWTGMSYQERL-SGNQAPALVAISFVV 882 Query: 350 VVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSINTLTLFAMVLAIGLLVDDAI 409 V + ++ + L VP+ ++G LF + + ++ IGL +AI Sbjct: 883 VFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAI 942 Query: 410 VVVENVERIMRDKGLPAREATEKSMGEISGALVAIALVLSAVFLPMAFFGGSTGVIYRQF 469 ++VE + +M +G EAT ++ ++ +L LP+A G+ Sbjct: 943 LIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAV 1002 Query: 470 SITIISAMLLSVVVALTLTPAL 491 I ++ M+ + ++A+ P Sbjct: 1003 GIGVMGGMVSATLLAIFFVPVF 1024
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.9 bits (114), Expect = 3e-08 Identities = 28/133 (21%), Positives = 56/133 (42%), Gaps = 10/133 (7%) Query: 41 PVSVVSELTGR-TSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNE 99 V +V+ G+ T + S E++P I+++ + KEG+ V+ G L ++ A +A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 100 ARAALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQSTCAQDKASV--------AA 151 +++L QA+ Q R L K + D Q+ ++ + + Sbjct: 139 TQSSLLQARLEQ-TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 152 KKAALETARINLD 164 + +NLD Sbjct: 198 WQNQKYQKELNLD 210 Score = 32.1 bits (73), Expect = 0.004 Identities = 17/114 (14%), Positives = 37/114 (32%), Gaps = 5/114 (4%) Query: 83 QPLYQIDAASYQAAWN--EARAALQQAQALVKADCQKAQRYARLVKEN--GVSQQDADDA 138 L A + A + K+ ++ + KE V+Q ++ Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 139 QSTCAQDKASVAAKKAALETARINLDWTTVTAPISGRI-GISSVTPGALVTASQ 191 Q ++ L + + AP+S ++ + T G +VT ++ Sbjct: 301 LDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 8e-12 Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 1 MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLSVGQIYRYFANKDAIIE 60 M K + ++ + I++ A R F + G + S+ +IA A ++ G IY +F +K + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMVRR 65 E+ Sbjct: 61 EIWEL 65
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.4 bits (120), Expect = 1e-09 Identities = 51/260 (19%), Positives = 98/260 (37%), Gaps = 22/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSDIVLQ 62 + GK +TG A I +A+ + +GA + A Y +KL+ V A+ Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 CDVAEDASIDTMFAELGKVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDI 119 DV + A+ID + A + + D V+ G L + A F + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVN--- 116 Query: 120 SSYSFVAMAKACRSMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 S+ F A + M++ +++T+ A + +KA+ + + + Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 PEGVRVNAISAGPIRTLAASGI--------KDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 +R N +S G T + + + L + P+++ D+ ++ Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 231 FLCSDLSAGISGEVVHVDGG 250 FL S + I+ + VDGG Sbjct: 237 FLVSGQAGHITMHNLCVDGG 256
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 31.0 bits (70), Expect = 0.018 Identities = 21/105 (20%), Positives = 36/105 (34%), Gaps = 2/105 (1%) Query: 526 PIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTAYSSLSQLARFPIDAIKLDQV 585 P+ V S I L S + FS + + ++ Q+ D + Sbjct: 425 PLVVVFVASNFINAHLLTDSFPRYFSDKS--IDFHSYYLLQDNVYQIPDLKPDLVITHSQ 482 Query: 586 FVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESAKEDAFLTK 630 + +H + V I L++Q + V+ K A LTK Sbjct: 483 LIPFVHHELTKGIAVAEISFDESILSIQELMYQVKEEKFQADLTK 527
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 4e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.9 bits (153), Expect = 5e-13 Identities = 34/188 (18%), Positives = 71/188 (37%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMXQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A + ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 4e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 361 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 418 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 419 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 478 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 479 KRNIQEMGG---HVEIQSKQGTGTTIRILLP 506 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.010 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>FLAGELLIN#Flagellin signature. Length = 507 Score = 237 bits (605), Expect = 6e-74 Identities = 252/525 (48%), Positives = 308/525 (58%), Gaps = 18/525 (3%) Query: 2 AQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 61 AQVINTNSLSL+TQNN+NK+QS+LSS+IERLSSGLRINSAKDDAAGQAIANRFTSNIKGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQAARNANDGISVAQTTEGALSEINNNLQRIRELTVQATTGTNSDSDLDSIQDEIKSRLD 121 TQA+RNANDGIS+AQTTEGAL+EINNNLQR+REL+VQAT GTNSDSDL SIQDEI+ RL+ Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVSGQTQFNGVNVLAKDGSMKIQVGANDGETITIDLKKIDSDTLGLNGFNVNGKGTI 181 EIDRVS QTQFNGV VL++D MKIQVGANDGETITIDL+KID +LGL+GFNVNG Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNG---- 176 Query: 182 TNKAATVSDLTSAGAKLNTTTGLYDLKTENTLLTTDAAFDKLGNGDKVTVGGVDYTYNAK 241 + + + TG D + NA Sbjct: 177 ----PKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAA 232 Query: 242 SGDFTTTKSTAGTGVDAAAQAADSASKRDALAATLHADVGKSVNGSYTTKDGTVSFETDS 301 +G TT + T VD +A +A A GK + Sbjct: 233 NGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTK-- 290 Query: 302 AGNITIGGSQAYVDDAGNLTTNNAGSAAKADMKKAAAATSSITFNSGVLSKTIGFTAGES 361 GN G ++ T +A A++ A +S + S V + ++ Sbjct: 291 TGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKN 350 Query: 362 SDAAKSYVDDKGGITNVADYTVSYSVNKDNGSVTVAGYASATDTNKDYAPAIGTAVNVNS 421 A S ++ + + TV A+ Sbjct: 351 ESAKLSDLEANNAVKGESKITV--------NGAEYTANAAGDKVTLAGKTMFIDKTASGV 402 Query: 422 AGKITTETTSAGSATTNPLAALDDAISSIDKFRSSLGAIQNRLDSAVTNLNNTTTNLSEA 481 + I + +A +T NPLA++D A+S +D RSSLGAIQNR DSA+TNL NT TNL+ A Sbjct: 403 STLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSA 462 Query: 482 QSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQ 526 +SRI+DADYATEVSNMSKAQI+QQAG SVLA+ANQVPQ VLSLL+ Sbjct: 463 RSRIEDADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 32.7 bits (74), Expect = 0.003 Identities = 24/72 (33%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 211 NGMEVSVAAQNAQLTVNNVAIENSSNTISDALENITLNLNDVTTGNQTLTITQDTSKAQT 270 N E +VAA+N + + A+ + +S AL T++L V+T LT T T ++ Sbjct: 236 NSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTS--LLTPTSLTGGEES 293 Query: 271 AIKDWVNAYNSL 282 +KD VNA L Sbjct: 294 MLKDQVNALKGL 305
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.9 bits (122), Expect = 4e-09 Identities = 33/129 (25%), Positives = 57/129 (44%), Gaps = 20/129 (15%) Query: 132 AMMLH-IRQQAQAQLPEAITQAVIGRPINFQGLGGDEANAQAQGILERAAKRAGFRDVVF 190 M+ H I+Q + ++ P+ + E A + +A+ AG R+V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV---ERRA-----IRESAQGAGAREVFL 140 Query: 191 QYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREASLLGHSGCRI 250 EP+AA + + E +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 251 GGNDLDIAL 259 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 33.2 bits (76), Expect = 0.002 Identities = 32/137 (23%), Positives = 55/137 (40%), Gaps = 23/137 (16%) Query: 332 RLSYRLV---RSAEECKIALSSV--AETRASLPFISDELAT------LISQQGLESALSQ 380 R +Y + +AE K + S + + LA ++ + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 381 PLARIQEQVQLALDNAQEKPDV--------IYLTGGSARSPLIKKALAEQLPGIPIAGGD 432 PL I V +AL+ Q P++ + LTGG A + + L E+ GIP+ + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 433 D-FGSVTAGLARWAEVV 448 D V G + E++ Sbjct: 320 DPLTCVARGGGKALEMI 336
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 44.0 bits (104), Expect = 3e-07 Identities = 43/195 (22%), Positives = 77/195 (39%), Gaps = 18/195 (9%) Query: 4 MPKFRVSLFSLALMLAVPLAPQAVAKTAAATTASQPEIASGSAMI-VDLNTNKVIYSNHP 62 M R+ + SL + +PLA A + S+ +++ MI +DL + + + + Sbjct: 1 MRYIRLCIISL--LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 63 DLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRV---RLNSEISRKDM 119 D P+ S K++ VL DE+L+ I + YS V L ++ ++ Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 120 LLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFV--EPTGLS-----V 172 A+ S+N +AA+L GG + A + +G N TR E Sbjct: 119 CAAAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETELNEALPGDA 173 Query: 173 HNVSTARDLTKLLIA 187 + +T + L Sbjct: 174 RDTTTPASMAATLRK 188
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.5 bits (105), Expect = 3e-07 Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 2/165 (1%) Query: 34 LDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLIT 93 L IA +F+ +S ++ TA L ++ G L D +RL++ ++ G +I Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 ASSQSLA-MMILGTALTGLFSVVAQILVPLA-ATLASPDKRGKVVGTIMSGLLLGILLAR 151 S ++I+ + G + LV + A + RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLANLGGWRTVFWVASVLMALMALALWRGLPQMKSETHLNY 196 + G++A+ W + + + + + + +++ + H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.017 Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 23 PYQEILLXRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALG 82 P QE+ L + + L R A+G + + T + ++L ALG Sbjct: 756 PEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTI-------ADLVQALG 808 Query: 83 -----SSRTNATRIADELEKRGWIERRESDNDRR 111 SS ++ D L + GW RE+ RR Sbjct: 809 ADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRR 842
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 74.1 bits (182), Expect = 2e-16 Identities = 64/412 (15%), Positives = 117/412 (28%), Gaps = 97/412 (23%) Query: 25 LLLTLLFIIIAVAIGIYWFLVLRHFEETDDA----YVAGNQIQIMSQVSGSVTKVWADNT 80 L FI+ + I VL E A +G +I + V ++ Sbjct: 57 PRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 81 DFVKEGDVLVTLDPTD-------------------------------------------- 96 + V++GDVL+ L Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 97 ---ARQAFEKAKTALASSVRQTHQQMINSKQ------------LQANIEVQKIALAKAQS 141 + T+L T Q K+ + A I + +S Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 142 DYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQ 201 + L + I + + + A +L V Q ++ IL K E Q Q Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 202 AATEVRN------------------AWLALERTRIVSPMTGYVSRRAVQ-PGAQISPTTP 242 E+ + + + I +P++ V + V G ++ Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 243 LMAVVPA-TNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKY---TGKVVGLDMGTGS 298 LM +VP + V A + I + +GQ I + + +Y GKV + + Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNI-----N 409 Query: 299 AFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLRIGLSTLVSVNTTNR 350 ++ G V+ + + PL G++ + T R Sbjct: 410 LDAIE--DQRLGLVFNVIISIEENCLST--GNKNIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 92.3 bits (229), Expect = 1e-22 Identities = 54/198 (27%), Positives = 89/198 (44%), Gaps = 4/198 (2%) Query: 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 76 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVKLFLWSTIAFAIASWACGVS-SSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAK 135 G +L L+ I S V S ++LI R IQG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETR 195 R A L V + GP +GG I+ HW + + +P+ + + L L +E R Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVR 194 Query: 196 TERRRIDAVGLALLVIGI 213 + D G+ L+ +GI Sbjct: 195 I-KGHFDIKGIILMSVGI 211
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 292 bits (748), Expect = e-105 Identities = 130/170 (76%), Positives = 147/170 (86%) Query: 2 PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFA 61 PLLDSFTVDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ E+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADVWKAAMEDVLKVQDQNQIP 121 GFMRNHLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VAD W AAMEDVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA++ILE V +N N+ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 66.6 bits (162), Expect = 2e-14 Identities = 28/170 (16%), Positives = 56/170 (32%), Gaps = 36/170 (21%) Query: 46 VLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQSDIALLQIQN---- 89 +LTN HV++ L +G ++ + D+A+++ Sbjct: 114 LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQN 173 Query: 90 ---PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLEN-FI 145 + ++++ + +V G P V+ + S + L+ + Sbjct: 174 KHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMWESKGKITYLKGEAM 226 Query: 146 QTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMART 195 Q D S GNSG + N E+IGI+ G+ + Sbjct: 227 QYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGAVFIN 267
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.045 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 169 bits (430), Expect = 4e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKDLYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 99 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 149 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 150 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 207 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 208 YRAEIT----PLGSNKVLKGTVDSVAA 230 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410 Score = 47.9 bits (114), Expect = 3e-08 Identities = 29/163 (17%), Positives = 58/163 (35%), Gaps = 17/163 (10%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVH-NQLVKKGQVLFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 113 V + V+KG VL + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 114 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 153 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 127 bits (321), Expect = 6e-39 Identities = 78/209 (37%), Positives = 122/209 (58%), Gaps = 3/209 (1%) Query: 1 MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFN 60 MA++TK EA +TRQ +++ A+ F+Q GVS T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-LQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEF 119 E+W L + ++ EL E A DP LRE LI L+ R++ L++I++HKCEF Sbjct: 61 EIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 NDEM-LAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLDVVMIIIDGAFSGIVQNWL 178 EM + + R + + + L+ C + + +L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNMAGYDLYKQAPALVDNVLRMFMPDENI 207 +DL K+A V +L M++ + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTL 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 38/217 (17%), Positives = 70/217 (32%), Gaps = 38/217 (17%) Query: 98 ATYQANYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 215 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 270 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 271 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEG 299 G + + ++ N L GM V A I G Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 7e-04 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 46 TAPLEVKTELPGR-TNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQANY 104 +E+ G+ T++ R E++P + IV EG V+ G L ++ +A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVE 164 + K++++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191 Score = 29.0 bits (65), Expect = 0.031 Identities = 11/34 (32%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 65 AEVRPQVSGIVLNRN-FTEGSDVQAGQSLYQIDP 97 + +R VS V TEG V ++L I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 848 bits (2193), Expect = 0.0 Identities = 616/627 (98%), Positives = 616/627 (98%) Query: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPDTTQDDISDYVASNVKDTLSRLNSVGDVQLFGA 180 EVQQQGISVEKSSSSYLMVAGFVSDNP TTQDDISDYVASNVKDTLSRLN VGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNAQIAAGQLGGTPALPGQQLNASIIAQTRL 240 QYAMRIWLDADLLNKYKLTPVDVINQLKVQN QIAAGQLGGTPALPGQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPTSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 SVLVALILTPALCATLLKP SAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQAPPQPHVF 627 EKANVESVFTVNGFSFSGQA F Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAF 627 Score = 96.8 bits (241), Expect = 7e-23 Identities = 77/511 (15%), Positives = 180/511 (35%), Gaps = 42/511 (8%) Query: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQ 63 + ++ +++ + L+LP + P P GA + Q + Q Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 64 VIEQNMNGIDNLMY---------MSSTSDSAGSVTITL-TFQSGTDPDIAQVQVQNKLQL 113 V + + + S + +AG ++L ++ + + V ++ ++ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 114 ATPLLP----QEVQQQGISVEKSSSSYLMVAGFVSDNPDTTQDDISDYVASNVKDTLSRL 169 + I +++ + + D D ++ + Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDF---ELIDQAGLGHDALTQARNQLLGMAAQHP 709 Query: 170 NSVGDVQLFGA--QYAMRIWLDADLLNKYKLTPVDVINQLKVQNAQIAAGQLGGTPALPG 227 S+ V+ G ++ +D + ++ D+ + G Sbjct: 710 ASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF----IDRG 765 Query: 228 QQLNASIIA-QTRLKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPA 286 + + A PE+ K+ +R +++G +V + R NG P+ Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVR-SANGEMVPFSAFTTSHWV-YGSPRLERYNGLPS 823 Query: 287 AGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFV---QLSIHEVVKT 343 + + A G ++ D ++ ++L P G YD T +LS ++ Sbjct: 824 MEIQGEAAPGTSSGDAMALMENLASKL----PAG----IGYDWTGMSYQERLSGNQAPAL 875 Query: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIG 403 + + ++VFL + ++ + + VP+ ++G F + M G++ IG Sbjct: 876 VAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIG 935 Query: 404 LLVDDAIVVVENVERVMMEDKLPPKEAT-EKSMSQIQGALV-GIAMVLSAVFIPMAFFGG 461 L +AI++VE + +M ++ EAT +++ L+ +A +L +P+A G Sbjct: 936 LSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG--VLPLAISNG 993 Query: 462 STGAIYRQFSITIVSAMALSVLVALILTPAL 492 + I ++ M + L+A+ P Sbjct: 994 AGSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 526 bits (1357), Expect = 0.0 Identities = 389/392 (99%), Positives = 391/392 (99%) Query: 1 MAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELI 60 MAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELI Sbjct: 625 MAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELI 684 Query: 61 DKAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSD 120 D+AGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSD Sbjct: 685 DQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSD 744 Query: 121 INQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSTNGEMVPFSAFT 180 INQTISTALGGTYVNDFIDRGRVKK+YVQADAKFRMLPEDVDKLYVRS NGEMVPFSAFT Sbjct: 745 INQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFT 804 Query: 181 TSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQ 240 TSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQ Sbjct: 805 TSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQ 864 Query: 241 ERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDV 300 ERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDV Sbjct: 865 ERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDV 924 Query: 301 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 360 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG Sbjct: 925 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 984 Query: 361 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 392 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLL Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Score = 68.3 bits (167), Expect = 2e-14 Identities = 54/316 (17%), Positives = 122/316 (38%), Gaps = 18/316 (5%) Query: 90 SVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTAL----GGTYVNDFIDRGRVKK 145 V+ G + ++ +D + ++ D+ + G G+ Sbjct: 174 DVQLFGAQ--YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLN 231 Query: 146 VYVQADAKFRMLPEDVDKLYVR-STNGEMVPFSAFTTSHWVYGSPRLE---RYNGLPSME 201 + A +F+ PE+ K+ +R +++G +V G R NG P+ Sbjct: 232 ASIIAQTRFKN-PEEFGKVTLRVNSDGSVVRLKDVARV--ELGGENYNVIARINGKPAAG 288 Query: 202 IQGEAAPGTSSGDA----MALMENLASKLPAGIGYDWT-GMSYQERLSGNQAPALVAISF 256 + + A G ++ D A + L P G+ + + +LS ++ + + Sbjct: 289 LGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAI 348 Query: 257 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 316 ++VFL + ++ + + VP+ ++G F + M G++ IGL + Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDD 408 Query: 317 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 376 AI++VE + +M ++ EAT ++ ++ ++ +P+A G+ Sbjct: 409 AIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 377 AVGIGVMGGMVSATLL 392 I ++ M + L+ Sbjct: 469 QFSITIVSAMALSVLV 484
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.004 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 1 MKR---LIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGG 57 MK+ L+ + L LA C+ + +V TN+ + T++ IAG Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN-------IAGD 53 Query: 58 AAAVAGLT 65 + + Sbjct: 54 KINLHSIV 61
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 141 bits (358), Expect = 1e-44 Identities = 65/142 (45%), Positives = 84/142 (59%), Gaps = 2/142 (1%) Query: 4 TLPFLILYACLSALLFFWDAKHGLLPDRFTCPLLWSGLLFYQVCHPDGLADALWGAIIGY 63 TL L+L L AL F D LLPD+ T PLLW GLLF + L DA+ GA+ GY Sbjct: 134 TLAALLLTWVLVALTFI-DLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGY 192 Query: 64 GTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHSWAFLPRLVFLAASFACGAVVIGLLM 123 +YW +++L KEG+GYGD K LAALGAW W LP +V L +S + IGL++ Sbjct: 193 LVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALP-IVLLLSSLVGAFMGIGLIL 251 Query: 124 RGKESLKNPLPFGPFLAAAGFV 145 P+PFGP+LA AG++ Sbjct: 252 LRNHHQSKPIPFGPYLAIAGWI 273
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 38.3 bits (89), Expect = 3e-06 Identities = 19/103 (18%), Positives = 43/103 (41%), Gaps = 10/103 (9%) Query: 44 EYHESIDEMKHADKYIERILFLEGIPN--LQDLGKL------GIGEDVEEMLQSDLRLEL 95 E ++ E D ER+L + G P +++ + G EM+Q+ + Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 96 EGAKDLREAIAYADSVHDYVSRDMMIEILADEEGHIDWLETEL 138 + + + + I A+ D + D+ + ++ + E + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 186 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 187 AKILELAGFLDSYIPEPE 204 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.7 bits (64), Expect = 0.024 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 164 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 222 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 223 SK 224 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 107 bits (269), Expect = 6e-31 Identities = 62/186 (33%), Positives = 100/186 (53%), Gaps = 8/186 (4%) Query: 28 AAKPATTADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKG 212 + + G Sbjct: 187 QLMPAG 192
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 7e-04 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 12 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 69 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 70 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 119 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 120 RYDALNRYPMSDVLR 134 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.033 Identities = 14/52 (26%), Positives = 20/52 (38%), Gaps = 5/52 (9%) Query: 1 MIVFSSLQIRRGVRVLLDNATATI-NPGQKVG----LVGKNGCGKSTLLALL 47 ++ + +L A + PG K L G G GKSTL+ L Sbjct: 565 YKPRRLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTL 616
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 676 bits (1745), Expect = 0.0 Identities = 352/896 (39%), Positives = 490/896 (54%), Gaps = 135/896 (15%) Query: 3 RKTVSRTFSSFSISVVAVAVASTFSAHAGKFNPKFLEDVQGVGQHVDLTMFEKGQEQQLP 62 RK F A A + S+ FNP+FL D DL+ FE GQ + P Sbjct: 19 RKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLAD--DPQAVADLSRFENGQ-ELPP 75 Query: 63 GIYRVSVYVNEQRMETRTLEFKEATEAQRKAMGESLVPCLSRTQLAEMGVRVESFPALNL 122 G YRV +Y+N M TR + F + +VPCL+R QLA MG+ S +NL Sbjct: 76 GTYRVDIYLNNGYMATRDVTFNTGDS------EQGIVPCLTRAQLASMGLNTASVSGMNL 129 Query: 123 VSAEACVPFDEIIPLASSHFDFSEQKLVLSFPQAAMHQVARGTVPESLWDEGIPALLLDY 182 ++ +ACVP +I A++ D +Q+L L+ PQA M ARG +P LWD GI A LL+Y Sbjct: 130 LADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNY 189 Query: 183 SFSGSNSEYDSTGSSSSYVDDNGTVHHDDGKDTLKSDSYYLNLRSGLNLGAWRLRNYSTW 242 +FSG++ + G+S YLNL+SGLN+GAWRLR+ +TW Sbjct: 190 NFSGNSVQNRIGGNS---------------------HYAYLNLQSGLNIGAWRLRDNTTW 228 Query: 243 S------HSGGKAQWDNIGTSLSRAIIPFKAQLTMGDTATAGDIFDSVQMRGAMLASDEE 296 S SG K +W +I T L R IIP +++LT+GD T GDIFD + RGA LASD+ Sbjct: 229 SYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDN 288 Query: 297 MLPDSQRGFAPIVRGIAKSN-----------------------------------AEVSI 321 MLPDSQRGFAP++ GIA+ +V+I Sbjct: 289 MLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTI 348 Query: 322 -EQNGYVIYRTYVQ-------------------AGNYDSA-----SPRFGQLDLIYGLPW 356 E +G + + AG Y S PRF Q L++GLP Sbjct: 349 KEADGST--QIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPA 406 Query: 357 GMTAYGGVLISNNYNAFTLGIGKNFGYIGAISIDVTQAKSELNNDRDSQGQSYRFLYSKS 416 G T YGG +++ Y AF GIGKN G +GA+S+D+TQA S L +D GQS RFLY+KS Sbjct: 407 GWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKS 466 Query: 417 F-ESGTDFRLAGYRYSTSGFYTFQEATDVRSDA-----------------DSDYNRYHKR 458 ESGT+ +L GYRYSTSG++ F + T R + D Y+KR Sbjct: 467 LNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKR 526 Query: 459 SEIQGNLTQQLGAYGSVYLNLTQQDYWNDAGKQNTVSAGYNGRIGKVSYSIAYSWNKSPE 518 ++Q +TQQLG ++YL+ + Q YW + AG N ++++++YS K+ Sbjct: 527 GKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAW 586 Query: 519 WDESDRLWSFNISVPLGR------------AWSNYRVTTDQDGRTNQQVGVSGTLLEDRN 566 D++ + N+++P A ++Y ++ D +GR GV GTLLED N Sbjct: 587 QKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNN 646 Query: 567 LSYSVQEGYASNG---VGNSGNANVGYQGGSGNVNVGYSYGKDYRQLNYSVRGGVIVHSE 623 LSYSVQ GYA G G++G A + Y+GG GN N+GYS+ D +QL Y V GGV+ H+ Sbjct: 647 LSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHAN 706 Query: 624 GVTLSQPLGETMTLISVPGARNARVVNNGGVQVDWMGNAIVPYAMPYRENEISLRSDSLG 683 GVTL QPL +T+ L+ PGA++A+V N GV+ DW G A++PYA YREN ++L +++L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLA 766 Query: 684 DDVDVENAFQKVVPTRGAIVRARFDTRVGYRVLMTLLRSAGSPVPFGATATLITDKQNEV 743 D+VD++NA VVPTRGAIVRA F RVG ++LMT L P+PFGA +T + ++ Sbjct: 767 DNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMT-LTHNNKPLPFGAM---VTSESSQS 822 Query: 744 SSIVGEEGQLYISGMPEEGRVLIKWGNDASQQCVAPYKLSLELKQGGIIPVSANCQ 799 S IV + GQ+Y+SGMP G+V +KWG + + CVA Y+L E +Q + +SA C+ Sbjct: 823 SGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.5 bits (100), Expect = 2e-06 Identities = 47/275 (17%), Positives = 94/275 (34%), Gaps = 32/275 (11%) Query: 44 PVSQVAFSFGLLSLGLAIS----SSVAGKLQERFGVKRVTIASGILLGLGFFLTAHSDNL 99 + V +G+L A+ + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFAIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDTQLLETVGLEKTFVIWGAIALVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMR 212 L+ F A+ + + G L+ ++ K E + R Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207 Query: 213 --KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQSLAHLDVVSAANAVTVISIAN-LS 265 ++AV F+ + L+VI + H D + ++ I + L+ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 266 GRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 ++ G ++ ++ R + +G + G L FA Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 36.7 bits (85), Expect = 1e-04 Identities = 37/155 (23%), Positives = 63/155 (40%), Gaps = 9/155 (5%) Query: 241 AQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 AH ++ A A+ + A + G L SD+ R V+ + + V A + A Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGAL-----SDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 301 PLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSICGSIIA 360 P V + I VA G T V + +++ + A+++G + FG G + G ++ Sbjct: 94 PFLWVLYIGRI--VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG 151 Query: 361 SLFGGFYVK--FYVIFALLILSLALSTTIRQPEQK 393 L GGF F+ AL L+ + K Sbjct: 152 GLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.8 bits (62), Expect = 0.040 Identities = 22/117 (18%), Positives = 47/117 (40%), Gaps = 16/117 (13%) Query: 121 SMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLS 180 S+ + D+ + H S + + + R G++ P ++SY F + Sbjct: 228 SVAVQQQDAKLV-EENYSHNSQTEVAATLAYRFGNVTP--RVSYAHGFKGSF-------- 276 Query: 181 RMTATNQNGNWLDVTVGADMLLNQNIAAYAA---LSQAENTTNNSDYLYTMGVSARF 234 ATN N ++ V VGA+ ++ +A + L + + + +G+ +F Sbjct: 277 --DATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 2e-04 Identities = 16/52 (30%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 76 VAPKAVRRGIGKALMQYV-----QQRYPHLMLEVYQKNQPAIDFYQAQGFHI 122 VA ++G+G AL+ + + LMLE N A FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 113 bits (285), Expect = 2e-32 Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 11/122 (9%) Query: 108 LNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEY--PKTAVNVIGYTDSTGGHDLNMRLS 165 + ++V F+ + ATLKP G L + L +V V+GYTD G N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A +I +G+G +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SP 218 Sbjct: 335 KG 336
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 9e-05 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG----------AEYTDAPA 71 V+R D +I N ILD + G + I +K IA +G P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDAHGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 1e-05 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 30 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 87 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 88 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 144 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 145 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLC 203 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 204 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 263 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 264 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 307 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 308 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 366 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 367 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 396 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.024 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 15/161 (9%) Query: 227 NVFFVYAVYCGLTFFIPFLKNIYLLP----------VALVGAYGIINQYCLKMIGGPIGG 276 N+ F+ V CG F + ++P A +G+ I +I G IGG Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 277 MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAVFF 336 ++ D+ + P L + + + L E+ ++ + G + FT+ Sbjct: 315 ILVDR--RGPLYVLNIGVTFLSVSFLTASFLL-ETTSWFMTIIIVFVLGGLSFTK--TVI 369 Query: 337 APIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDL 377 + I + + + + GA M+L +F + ++ G +L + Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.007 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 20 AAGTVKVFSNGSSEAKTLTGAEHLIDLVGQPRLANSWWPGAVISEELATAAALRQQQALL 79 A + + + LT + L D+V + N+ + A AA++ + L Sbjct: 73 AKAAAEAQAKAKANRDALT--QRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERL 130 Query: 80 TRLAEQGADSSADDAAAINALRQQIQALKVTGRQK 114 RLA+ + + AA A ++ Q K R+K Sbjct: 131 -RLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREK 164
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 4e-04 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 279 VIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMT--- 335 +I ++ ++ VGI +++ P + + L S D+ I++ + L A + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 336 VDKFGRKPLQIIGALGMAIGMFSLGTA 362 D+FGR+P+ ++ G A+ + TA Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATA 93
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 756 bits (1953), Expect = 0.0 Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK Sbjct: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 Query: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 Query: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 Query: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 Query: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP Sbjct: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 Query: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK Sbjct: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 32 VVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKR 66 VV G G GKSTL+ + GL+ + IG + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.020 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.3 bits (102), Expect = 2e-06 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 55/290 (18%) Query: 85 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGE 144 G L D++GR+ +L +++ ++ + P +W +L I ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 145 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGW 200 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 201 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRS 260 PFF A L + L K E+ P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 261 LLTCIGLVIATNVTYYML----LTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVM 315 +T + ++A ++ + H+ G+ + ++ L + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 316 GLLSDRFGRRPFVLLG----SVALFVLA--------IPAFILINSNVIGL 353 G ++ R G R ++LG +LA P +L+ S IG+ Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Score = 39.0 bits (91), Expect = 4e-05 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 286 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFI 344 L H+ + +G+L+ + A+M PV+G LSDRFGRRP +L+ L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLVS---LAGAAVDYAI 89 Query: 345 LINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIR---YSALAAAFNISVLVAG 401 + + + +++ G ++A I V + + + R + ++A F +VAG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 402 LTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITG-VTMKETANR 444 P L + S + P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFSPH--APFFAAAALNGLNFLTGCFLLPESHKG 187
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 34/182 (18%) Query: 181 ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDV-ILPSYDELSTML--DQRQQTLL 237 + +M+ S+S+L++ S N + V L +++ ++ SY +L+++ D+ Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 238 LPESAADITVQGDATLLRMLLRNLVENAHRY----SPQGSNIMIKLQEDGGAV-MAVEDE 292 + + D+ V ML++ LVEN ++ PQG I++K +D G V + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 293 GPGIDESKCGELSKAFVRMDSRYGGIGLGLSIV-SRITQLHHGQFFLQNRQETSGTRAWV 351 G + + G GL V R+ L+ + ++ ++ A V Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 352 RL 353 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-23 Identities = 41/121 (33%), Positives = 60/121 (49%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLH 61 IL+ +DD + L A GY + A + + AG LVV D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNN 121 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 Q 122 + Sbjct: 125 R 125
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.020 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWSWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 996 bits (2576), Expect = 0.0 Identities = 797/878 (90%), Positives = 802/878 (91%), Gaps = 58/878 (6%) Query: 1 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAVQAPLSSAELYFNPRFLADDPQA 60 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFA QAPLSSAELYFNPRFLADDPQA Sbjct: 1 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQA 60 Query: 61 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN Sbjct: 61 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120 Query: 121 TASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTIPQAFMSNRARGYIPPELWDP 180 TASV+GMNLLADDACVPLT+M+ DATA LDVGQQRLNLTIPQAFMSNRARGYIPPELWDP Sbjct: 121 TASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDP 180 Query: 181 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDRSSGSK 240 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSD SSGSK Sbjct: 181 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSK 240 Query: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV Sbjct: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 Query: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV Sbjct: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 Query: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY Sbjct: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 Query: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR Sbjct: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480 Query: 481 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRS 540 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR+ Sbjct: 481 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT 540 Query: 541 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLARNVNI 600 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLA NVNI Sbjct: 541 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600 Query: 601 PFSHWLRSDSKSQWRHASASYSMSGYSHSDDIKQ------------LYYGVSGG------ 642 PFSHWLRSDSKSQWRHASASYSMS + L Y V G Sbjct: 601 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD 660 Query: 643 ----------------------------------------VLAHANGVTLGQPLNDTVVL 662 VLAHANGVTLGQPLNDTVVL Sbjct: 661 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL 720 Query: 663 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP 722 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP Sbjct: 721 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP 780 Query: 723 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA 782 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA Sbjct: 781 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA 840 Query: 783 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 820 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR Sbjct: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.4 bits (68), Expect = 0.003 Identities = 30/158 (18%), Positives = 49/158 (31%), Gaps = 9/158 (5%) Query: 3 WRKRGYLLAAILALASATIQAADVTITVNGKVVAKPCTVSTTNATVDLGDLYSFSLMSAG 62 W R + A LA + +TI + VT VN + + + + G Sbjct: 258 WMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTH------IG 311 Query: 63 AASAWHDVALELTNCPVG--TSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLN 120 W L + P G + S + Q ++QN + N+ Sbjct: 312 TLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQ 371 Query: 121 TGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQA 158 + QV D + V +N A GTI+ Sbjct: 372 KTEIQPTQVIDGPFAGGKNTVVNINRINTNA-DGTIRV 408
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.1 bits (62), Expect = 0.044 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 211 SQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVS 270 S+N G ++ +A+ N FT PA V V L ++G ++ + + + Sbjct: 133 SENAGKEITIGSAN-PNVTFTEKTGDQPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYN 191 Query: 271 LGLTANYARTGGQVTAGNV 289 + TG VT G V Sbjct: 192 SNVNFYDVTTGATVTTGAV 210
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 10/49 (20%), Positives = 25/49 (51%) Query: 230 LVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFV 278 + +I ++ I +W V +T W ++ FI + P+A + + ++ + Sbjct: 73 MGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSII 121
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 490 bits (1262), Expect = e-180 Identities = 253/262 (96%), Positives = 255/262 (97%) Query: 1 MAYRSAPLYEDIIWRTHLQPQDARLAQAVRATIAEHREHLLEFIRLDEPAPLNAMTLAQW 60 MAYRSAPLYED+IWRTHLQPQD LAQAVRATIA+HREHLLEFIRLDEPAPLNAMTLAQW Sbjct: 1 MAYRSAPLYEDVIWRTHLQPQDPTLAQAVRATIAKHREHLLEFIRLDEPAPLNAMTLAQW 60 Query: 61 SSPNALSSLLAVYSDHIYRNQPTMIREYKPLISLWAQWYIGLMVPPLMLALLTQEKALDV 120 SSPN LSSLLAVYSDHIYRNQP MIRE KPLISLWAQWYIGLMVPPLMLALLTQEKALDV Sbjct: 61 SSPNVLSSLLAVYSDHIYRNQPMMIRENKPLISLWAQWYIGLMVPPLMLALLTQEKALDV 120 Query: 121 SPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQQRMETLISQALVPVVQALEATGEING 180 SPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQ RMETLISQALVPVVQALEATGEING Sbjct: 121 SPEHFHAEFHETGRVACFWVDVCEDKNATPHSPQHRMETLISQALVPVVQALEATGEING 180 Query: 181 KLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLTTGEDNPLWRTVVLRDGLLV 240 KLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLT GEDNPLWRTVVLRDGLLV Sbjct: 181 KLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEKTLTNGEDNPLWRTVVLRDGLLV 240 Query: 241 RRTCCQRYRLPDVQQCGDCTLK 262 RRTCCQRYRLPDVQQCGDCTLK Sbjct: 241 RRTCCQRYRLPDVQQCGDCTLK 262
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 54.6 bits (131), Expect = 4e-12 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 62 DEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFN 121 A + +IAV DY+++G+G ALL I+ ++ L LE + N +A Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 122 EATIRRNYYPTTDG-REDAI 140 + Y E AI Sbjct: 148 IGAVDTMLYSNFPTANEIAI 167
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 216 bits (551), Expect = 8e-65 Identities = 107/460 (23%), Positives = 208/460 (45%), Gaps = 44/460 (9%) Query: 12 KRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISIT 71 K +++H DAGKTT+TE +L AI G+V ++D +E+QRGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSV----DKGTTRTDNTLLERQRGITIQ 57 Query: 72 TSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTR 131 T + F + + VN++DTPGH DF + YR+L+ +D +++I A GV+ +TR L R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 132 LRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETY 191 P + F+NK+D++ D + +++ +L K + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVI------------------KQKVE 159 Query: 192 LYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEI 251 LY + E + + +DL ++ L + + F + Sbjct: 160 LYPNMCVTNFTESEQWDTVIEGN------DDLLEKYMSGKSLEALELEQEESIRFHNCSL 213 Query: 252 TPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKH 311 PV+ G+A N G+D++++ + + + + G VFKI+ K Sbjct: 214 FPVYHGSAKNNIGIDNLIEVITNKFYSS---------THRGQSELCGKVFKIE--YSEK- 261 Query: 312 RDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHG 371 R R+A++R+ SG +R K + I++ T + G+ +++AY G+I+ L N Sbjct: 262 RQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNEF 320 Query: 372 TIQIGDTFTQGEMMKFTGIPNFA-PELFRRIRLKDPLKQKQLLKGLVQLSEEG-AVQVFR 429 +++ +++ P L + P +++ LL L+++S+ ++ + Sbjct: 321 -LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379 Query: 430 PISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVA 469 + +++I+ +G +Q +V A L+ +Y+VE + V Sbjct: 380 DSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVI 419
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 26.6 bits (58), Expect = 0.006 Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 8/49 (16%) Query: 10 WGIIFLVIALIA--------AALGFGGLAGTAAGAAKIVFVVGIILFLV 50 W +FL + A AL F LAGT G I V GI+ + Sbjct: 460 WKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYI 508
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.013 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 6e-22 Identities = 33/139 (23%), Positives = 60/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQQVPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+ V + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSTPSPVIRIGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.006 Identities = 45/207 (21%), Positives = 80/207 (38%), Gaps = 51/207 (24%) Query: 240 LTQNARMQAL---------VETL--LRQARLENRQEVVLTAVDVAALFR---RVSEARTV 285 + Q A++ AL L +R LE+ + ++ L R R S AR V Sbjct: 157 MAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQV 216 Query: 286 QLAE--KNITLHVM--------PTEVNVAAEPALLEQALGNLL-----DNA----IDFTP 326 LA+ + ++ + PA+++ + +L +N I P Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLP 276 Query: 327 KSGRITLSAEVDQEHVALKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE 386 + G+I L D V L+V +TGS N ++S+G GL V E Sbjct: 277 QGGKILLKGTKDNGTVTLEVENTGSLALK----------------NTKESTGTGLQNVRE 320 Query: 387 -VARLFNGEVTLR-NVQEGGVLASLRL 411 + L+ E ++ + ++G V A + + Sbjct: 321 RLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122