>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.3 bits (65), Expect = 0.021 Identities = 26/139 (18%), Positives = 48/139 (34%), Gaps = 10/139 (7%) Query: 167 ESNIERLSNTLANLEQTTGAFASQKGGIADAIEQLAQVGKQANATLAETQALMRNANGLL 226 E+ L+ A+LE+ + + I+ L A AE + + A Sbjct: 217 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFS 276 Query: 227 GT------QGKQAIGSAEQAMQSLAESTATINSLLQDNRQSLDDSAQGLNQIAPAIRELR 280 + + E L + +N+ Q R+ LD S + Q+ ++L Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE 336 Query: 281 ETLN----SLKGISRRLEA 295 E S + + R L+A Sbjct: 337 EQNKISEASRQSLRRDLDA 355
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 29.8 bits (67), Expect = 0.017 Identities = 15/78 (19%), Positives = 28/78 (35%), Gaps = 10/78 (12%) Query: 78 QPLLRFATQMIHQESLFF-VLPFFFITTTWNSGQLI-FTGLL------GAAGLISIVDPL 129 P++ + Q++ L FF + +N I T L G L + + + Sbjct: 330 NPIITLLPNLKEQKASLVKALMFFSKSFLFNLQHFIPETNLFVSPYYKGNQKLYTSLKLI 389 Query: 130 YHKWLA--PRRWLFLALH 145 +W+A P + H Sbjct: 390 VEEWMAKLPGKRYLNHKH 407
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.7 bits (69), Expect = 0.013 Identities = 30/102 (29%), Positives = 38/102 (37%), Gaps = 13/102 (12%) Query: 297 SALGIASGVVAGLVAITPAAGTVGPMGALVIGLVS--GVVCYF-CATSLK------RKLG 347 S IA GL AAG + L I +S + F A ++ +KLG Sbjct: 288 SQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLG 347 Query: 348 YD-DSLDAFGVHGIGGIIGALLTGVFAAPALGGFGAVTDIAA 388 YD DSL A G I A LT + L + AA Sbjct: 348 YDGDSLLAAFHKE-TGAIDASLTTIST--VLASVSSGISAAA 386
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 5e-18 Identities = 26/137 (18%), Positives = 51/137 (37%), Gaps = 9/137 (6%) Query: 3 VLIVDDEPQARERLSRLLGELEGYTVMEPSATNGEEALTLIESLKPDVVLLDIGMPGLDG 62 +L+ DD+ R L++ L GY V +N I + D+V+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQAL-SRAGYDVR--ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 LQVAARLCERESPPAVVFCTDEYGS-----EAFRDSTLSHVDKPIQPQALRDALRRAEKP 117 + R+ + V+ + + +A ++ KP L + RA Sbjct: 63 FDLLPRIKKARPDLPVLVMSA-QNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 118 NRAQLAALTRAASDAGG 134 + + + L + D Sbjct: 122 PKRRPSKLEDDSQDGMP 138
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.024 Identities = 10/91 (10%), Positives = 29/91 (31%), Gaps = 2/91 (2%) Query: 56 RQLQGSEQGQGEHLQALNQRADALQQREQQLSAQLASLPAASELEDRRRLVAQLQGDQQR 115 L E+ + + +L + + + + A +EL + + Q++ + Sbjct: 227 ENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVE--AVNELRVYKSQLEQIESEILS 284 Query: 116 LSQRLETVLGESRKEWRLAEAEHLLRLATLR 146 + + V + E + + L Sbjct: 285 AKEEYQLVTQLFKNEILDKLRQTTDNIGLLT 315
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 122 bits (307), Expect = 1e-36 Identities = 70/221 (31%), Positives = 115/221 (52%), Gaps = 8/221 (3%) Query: 6 ILGLCLVMPLALANAETAPANDSDLAYSLGASLGERLRQEVPGLQLDALVEGLRQAYQGQ 65 I+GL + +A +A + + L+YS+GA LG+ + + + D L +G++ G Sbjct: 10 IMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGIDINPDVLAKGMQDGMSGA 69 Query: 66 PPRIAKSRMQAILEQHETQANAAAEQAQVDKLVEAEKR----FIAGERAKTGVRELPEGI 121 + + +M+ +L + + A A+ +K E K F++ ++K G+ LP G+ Sbjct: 70 QLILTEEQMKDVLSKFQKDL-MAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPSGL 128 Query: 122 LYSELASGSGAQPKASGRVQVRYVGKLPDGTVFD---QNLQPQWFKLDSVIEGWQLALPR 178 Y + +G+GA+P S V V Y G L DGTVFD + +P F++ VI GW AL Sbjct: 129 QYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQL 188 Query: 179 MKAGAKWRLVIPSAQAYGADGAGDLIAPYTPLVFEIELLDV 219 M AG+ W + +P+ AYG G I P L+F+I L+ V Sbjct: 189 MPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.8 bits (147), Expect = 4e-12 Identities = 40/226 (17%), Positives = 63/226 (27%), Gaps = 14/226 (6%) Query: 133 RTAAPKAAAKAAAKPAAKPAAAKAPARTAAAKPAAKPAAKPAAAKAPARTAAAKPAAKPA 192 +T A P+ A+ P PA A T +K Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSN--NEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 193 AKPTAAKAPAKTAAAKPAAKPAAKPAAAKAPAKTAAAKPAAKPAAKPAAAKAPAKTAAAK 252 +K T K + AK A + A T + A+ + +T K Sbjct: 1048 SK-TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE-----VAQSGSETKETQTTETK 1101 Query: 253 PAAKPAAKPAAAKAPAKTAAAKPAAKSAAKPAAAKAPAKPAAAKPAAKPAAKPAAKPAAA 312 A K AK + P S P ++ A+PA + Sbjct: 1102 ETAT-VEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPT-----VNI 1155 Query: 313 KAPAKPVASKPAESQPATPTASTTPAPANSAATPAATATPAQSSTS 358 K P + QPA T+S P + T + ++ + Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Score = 46.2 bits (109), Expect = 1e-07 Identities = 27/183 (14%), Positives = 45/183 (24%), Gaps = 7/183 (3%) Query: 181 RTAAAKPAAKPAAKPTAAKAPAKTAAAKPAAKPAAKPAAAKAPA---KTAAAKPAAKPAA 237 +T P + A+ P APA +T Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEI--ARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 238 KPAAAKAPAKTAAAKPAAKPAAKPAAAKAPAKTAAAKPAAKSAAKPAAAKAPAKPAAAKP 297 K + AK A + A T + A+S ++ + A Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE-VAQSGSETKETQTTETKETATV 1106 Query: 298 AAKPAAKPAAKPAAAKAPAKPVASKPAESQPATPTASTTPAPANSAATPAATATPAQSST 357 + AK + P P + Q T PA N ++T Sbjct: 1107 EKEEKAK-VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT 1165 Query: 358 SAS 360 + + Sbjct: 1166 ADT 1168 Score = 41.2 bits (96), Expect = 6e-06 Identities = 28/245 (11%), Positives = 66/245 (26%), Gaps = 11/245 (4%) Query: 21 SLLEHLEDACSQALADAEKLLAK-LEKQRGKAQEKLHNARLKLQDAAKAGKAKAQ----- 74 ++ +A+ K +K +EK A E R ++A KA Q Sbjct: 1027 PPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA 1086 Query: 75 --GKAQKVAGELEDLLDSLKDRQAQTRTYIQQLKRDAQESLKLAQGVGKVREAAAKALDS 132 G K E + +++ + + ++ + + + +++ + +A + Sbjct: 1087 QSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 133 RTAAPKAAAKAAAKPAAKPAAAKAPARTAAAKPAAKPAAKPAAAKAPARTAAAKPAAKPA 192 R P K A + PA+ ++ + + Sbjct: 1147 RENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206 Query: 193 AKPTAAKAPAKTAAAKPAAKPAAKPAAAKAPAKTAAAKPAAKPAAKPAAAKAPAKTAAAK 252 +PT + + + P + + A + Sbjct: 1207 TQPTVNSESSNKPKNRHRRSVRSVPHNVEPA---TTSSNDRSTVALCDLTSTNTNAVLSD 1263 Query: 253 PAAKP 257 AK Sbjct: 1264 ARAKA 1268
>cloacin#Cloacin signature. Length = 551 Score = 27.4 bits (60), Expect = 0.019 Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 7/65 (10%) Query: 40 AYNKQTAERELKAAYDDLMQRIRDQYADESDKAAALSGKMEAAEKLWAQLRDADCKVETW 99 A QT +AA+D + ++SD AALS ME+ +K + R A+ + Sbjct: 397 AQRAQTDVNNKQAAFDAAAK-------EKSDADAALSSAMESRKKKEDKKRSAENNLNDE 449 Query: 100 AEKPG 104 KP Sbjct: 450 KNKPR 454
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 9e-04 Identities = 47/204 (23%), Positives = 73/204 (35%), Gaps = 27/204 (13%) Query: 5 LLPILLFAALGLAVLGALRRVRMWRRGRPSKVDLIGGL----LAMPRRYLVDLHHVVERD 60 LL L AA+ A++ + + GR ++ G+ A+ Y+ D+ ER Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGR-----IVAGITGATGAVAGAYIADITDGDERA 130 Query: 61 RYMSRTHVATAGGFVLSAVLAILVHGFGLHSKILGYALLVATVIMFTGALFVF----KRR 116 R+ G V VL L+ GF H+ A L + F F+ K Sbjct: 131 RHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAAL--NGLNFLTGCFLLPESHKGE 188 Query: 117 LDPPSRLSKGP-----WMRLPKSLLMFAASFFIATLPVAGILPEGTGGWVLVALLGIGVL 171 P R + P W R + A FFI L G +P WV+ Sbjct: 189 RRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLV--GQVPAAL--WVIFGEDRFH-- 242 Query: 172 WGVSELFFGMTWGGPMKHAFAGAL 195 W + + + G + H+ A A+ Sbjct: 243 WDATTIGISLAAFGIL-HSLAQAM 265
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.6 bits (63), Expect = 0.023 Identities = 16/66 (24%), Positives = 30/66 (45%), Gaps = 8/66 (12%) Query: 190 DNLKGAAAVLSLGATGIEI--------LIASVDIYQAVQKNRRVDVRHEADMLRQAQEND 241 DNL A + L A IEI L + ++ A+Q+ R+ ++ ++ ++ Sbjct: 248 DNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEFQEETRKA 307 Query: 242 ELLNRL 247 E NR+ Sbjct: 308 EETNRI 313
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 30.6 bits (69), Expect = 0.013 Identities = 26/127 (20%), Positives = 41/127 (32%), Gaps = 23/127 (18%) Query: 10 LALTIALVIGAPLAVAAEPAKPAAKPAAVPATEVTAKAPLPLEELRTFAEVMDRIKAAYV 69 L L ++ +I A + K V T + + D K Sbjct: 8 LVLFLSAIILVACASGKKDTTSGQKLKVVA----------------TNSIIADITKNI-- 49 Query: 70 EPVDDKTLLENAIKGMLSNLDPHSAYLGPEDFQELQESTSGEFGGLGIEVGMEDGFVKVV 129 DK L + + DPH PED ++ E+ + G+ +E G F K+V Sbjct: 50 --AGDKIDLHSIVP---IGQDPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLV 104 Query: 130 SPIDDTP 136 T Sbjct: 105 ENAKKTE 111
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.4 bits (112), Expect = 7e-08 Identities = 45/276 (16%), Positives = 96/276 (34%), Gaps = 11/276 (3%) Query: 19 ADERAQTQQQLDATRQDIAELKKMLGKLQEEKAGVQKDLKSTETDIGNLEKQVEALQQEL 78 + + D ++++ K+ L K + + ++ E +LEK +E Sbjct: 77 SFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALEGAMNFS 136 Query: 79 KKTEGELERLDHEKKKLQSARVEQQRLI-----AIQARSAYQNNGREEYLKLLLNQQNPE 133 +++ L+ EK L + + + ++ + A SA E L Q E Sbjct: 137 TADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELE 196 Query: 134 KFARTLTYYDYLSKARMEQLRAFNETLRQLANVEQDIARQQEQLLTQRADLDGRRQALVA 193 K L S A +++ LA + D+ + E + + + L A Sbjct: 197 K---ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 253 Query: 194 ERDKRQQVLAKLNSDMKERDQKLQSREQDQADLGKVLKTIEETLARQAREAE-EARQRAL 252 E+ + A+L ++ + L +E A +++ R Sbjct: 254 EKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQS 313 Query: 253 LARQEEEKRRKEQALAA--ARTQEPEEAPKKARTTL 286 L R + R ++ L A + +E + + +R +L Sbjct: 314 LRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSL 349 Score = 44.3 bits (104), Expect = 6e-07 Identities = 53/263 (20%), Positives = 91/263 (34%), Gaps = 16/263 (6%) Query: 19 ADERAQTQQQLDATRQDIAELKKMLGKLQEEKAGVQKDLKSTETDIGNLEKQVEALQQEL 78 A +A ++ L+ + L+ EKA ++ E + A ++ Sbjct: 154 AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213 Query: 79 KKTEGELERLDHEKKKLQSARVEQQRLIAIQARSAYQNNGREEYLKLLLNQQNPEKFART 138 K E E L K L+ A A SA E L Q EK Sbjct: 214 KTLEAEKAALAARKADLEKALEGAMNFS--TADSAKIKTLEAEKAALEARQAELEKALEG 271 Query: 139 LTYYDYLSKARMEQLRAFNETLRQLANVEQDIARQQEQLLTQRADLDGRRQALVAERDKR 198 + A+++ L A L E + A + Q A+ R+ L A R+ + Sbjct: 272 AMNFSTADSAKIKTLEAEKAAL------EAEKADLEHQSQVLNANRQSLRRDLDASREAK 325 Query: 199 QQVLAKLNSDMKERDQKLQSREQDQADLGKVLKTIEETLA--------RQAREAEEARQR 250 +Q+ A+ ++ SR+ + DL + ++ A + EA R Sbjct: 326 KQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 385 Query: 251 ALLARQEEEKRRKEQALAAARTQ 273 L E K++ E+AL A ++ Sbjct: 386 RDLDASREAKKQVEKALEEANSK 408 Score = 39.3 bits (91), Expect = 3e-05 Identities = 49/286 (17%), Positives = 104/286 (36%), Gaps = 32/286 (11%) Query: 17 AFADERAQTQQQLDATRQDIAELKKMLGKLQEEKAGVQKDLKSTETDIGNLEKQVEALQQ 76 + ++ + A L+ +L++ G + I LE + AL+ Sbjct: 236 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEA 295 Query: 77 ELKKTEGELERLDHEKKKLQSARVEQQRLIAIQARSAYQNNGREEYLKLLLNQQNPEKFA 136 E E + + L+ ++ L+ + E+ KL + E Sbjct: 296 EKADLEHQSQVLNANRQSLRRDLDASREAKK---------QLEAEHQKLEEQNKISEASR 346 Query: 137 RTLTYYDYLSKARMEQLR-AFNETLRQLANVEQDIARQQEQLLTQRADLDGRRQAL---- 191 ++L + ++ R A + + +E+ + + R DLD R+A Sbjct: 347 QSL-------RRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVE 399 Query: 192 --VAERDKRQQVLAKLNSDMKERDQ-KLQSREQDQADLGKVLKTIEETLARQAREAEEAR 248 + E + + L KLN +++E + + + + QA L K ++E LA+QA E + R Sbjct: 400 KALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLR 459 Query: 249 QRALLARQEEEKRRKEQAL--------AAARTQEPEEAPKKARTTL 286 Q + + +A+ A + + + K+ + L Sbjct: 460 AGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQL 505
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 213 bits (543), Expect = 5e-74 Identities = 82/160 (51%), Positives = 111/160 (69%), Gaps = 5/160 (3%) Query: 1 MTEQQTNGATDANA---PQFSLQRIYVRDLSFEAPKSPQIFRQQWEPSVSLDLNTRQKAL 57 M+E+ A D A P +QRIYV+D+SFEAP P IF+Q WEP +S DL+T K + Sbjct: 1 MSEENQVNAADTQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQV 60 Query: 58 EGDFHEVVLTLSV--TVKNGDEVAFIAEVQQAGIFLIANLDAASMSHTLGAFCPNILFPY 115 D +EV L +SV T+++ +VAFI EV+QAG+F I+ L+ M+H L + CPN+LFPY Sbjct: 61 GDDLYEVCLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPY 120 Query: 116 ARETLDSLVTRGSFPALMLSPVNFDALYAQEMQRMQEAGE 155 ARE + SLV RG+FPAL LSPVNFDAL+ +QR ++A + Sbjct: 121 ARELVSSLVNRGTFPALNLSPVNFDALFMDYLQRQEQAEQ 160
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 556 bits (1434), Expect = 0.0 Identities = 201/480 (41%), Positives = 299/480 (62%), Gaps = 16/480 (3%) Query: 1 MSRSETVWIVDDDRSIRWVLEKALQQEGMTTQSFDSADGVMGRLARQQPDVIISDIRMPG 60 M+ + T+ + DDD +IR VL +AL + G + +A + +A D++++D+ MP Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 ASGLDLLAQIREQHPGLPVIIMTAHSDLDSAVASYQGGAFEYLPKPFDVDEAVSLVKRAN 120 + DLL +I++ P LPV++M+A + +A+ + + GA++YLPKPFD+ E + ++ RA Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 QHAQEQQALEVPQALARTPEIIGEAPAMQEVFRAIGRLSHSNITVLINGESGTGKELVAH 180 + + + ++ ++G + AMQE++R + RL +++T++I GESGTGKELVA Sbjct: 120 AEPKRRPS-KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 181 ALHRHSPRAASPFIALNMAAIPKDLMESELFGHEKGAFTGAANLRRGRFEQADGGTLFLD 240 ALH + R PF+A+NMAAIP+DL+ESELFGHEKGAFTGA GRFEQA+GGTLFLD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 241 EIGDMPADTQTRLLRVLADGEFYRVGGHVPVKVDVRIIAATHQNLESLVQAGKFREDLFH 300 EIGDMP D QTRLLRVL GE+ VGG P++ DVRI+AAT+++L+ + G FREDL++ Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 301 RLNVIRIHIPRLADRREDIPALARHFLGRAAQELAVEPKLLKPETEEFIRNLPWPGNVRQ 360 RLNV+ + +P L DR EDIP L RHF+ +A +E ++ K E E ++ PWPGNVR+ Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 361 LENTCRWITVMASSREVLVGDLPP----ELLNLPQDAAPVTNWEQALRQWADQALAR--- 413 LEN R +T + + + E+ + P + A + ++ Q ++ + + Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 414 ------GQSSLLDSAVPSFERIMIETALKHTAGRRRDAALLLGWGRNTLTRKIKELGMKV 467 S L D + E +I AL T G + AA LLG RNTL +KI+ELG+ V Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 6e-16 Identities = 34/144 (23%), Positives = 53/144 (36%), Gaps = 8/144 (5%) Query: 641 ARVLVVDDNDTCRKVLVQQCSAWGMNVSAVPSGKEALALLRTKAHLRDYFDAVLLDQNMP 700 A +LV DD+ R VL Q S G +V + + D V+ D MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-----AGDGDLVVTDVVMP 58 Query: 701 GMTGMQLAAKIKEDPSLNHDILVVMLTGISNAPSKIIARNAGVKRILAKPVAGYTLKTTL 760 L +IK+ D+ V++++ + + I A G L KP L + Sbjct: 59 DENAFDLLPRIKK---ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115 Query: 761 AEELALRGREQAAPPLPAGSPVPL 784 LA R + + +PL Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMPL 139 Score = 64.1 bits (156), Expect = 1e-12 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 5/117 (4%) Query: 791 RILVAEDNSISTKVIRGMLGKLNLEPDTASNGEEALQAMKARHYDLVLMDCEMPVLDGFS 850 ILVA+D++ V+ L + + SN + + A DLV+ D MP + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 851 ATEQLRAWETANQRPRTPVVALTAHILNEHKERARLAGMDGHMAKPVELSQLRELIQ 907 +++ RP PV+ ++A +A G ++ KP +L++L +I Sbjct: 65 LLPRIKKA-----RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 108 bits (272), Expect = 7e-28 Identities = 78/365 (21%), Positives = 134/365 (36%), Gaps = 60/365 (16%) Query: 22 VGIDLGTTNSLVAAVRSGRSEPLPDAQGSVILPSAVRYLDNAVEVGLAAREAAPSDPLNS 81 + IDLGT N+L+ G + PS V A R+ P S Sbjct: 13 LSIDLGTANTLIYVKGQGI---------VLNEPSVV-----------AIRQDRAGSP-KS 51 Query: 82 ILSV----KRLMGRGLADVKQLGEQLPYRFVGGESHMPFIDTVQGPKSPVEVSADILK-V 136 + +V K+++GR ++ + P D V V+ +L+ Sbjct: 52 VAAVGHDAKQMLGRTPGNIAAI--------------RPMKDGVIA---DFFVTEKMLQHF 94 Query: 137 LRQRAEETLGGELVGAVITVPAYFDDAQRQATKDAAKLAGLNVLRLLNEPTAAAVAYGLD 196 ++Q + ++ VP +R+A +++A+ AG + L+ EP AAA+ GL Sbjct: 95 IKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLP 154 Query: 197 QDAEGVVAIFDLGGGTFDISILRLTAGVFEVLATGGDTALGGDDFDHAIAGWIIEQAGLS 256 + D+GGGT +++++ L V +GGD FD AI ++ G Sbjct: 155 VSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSL 209 Query: 257 ADLDPATQRLLLQTACAAKEALTDSDAVS----VQHGAWQGELT-RAAFEAMIEPMIARS 311 + +R+ + A V + L EA+ EP + Sbjct: 210 IG-EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEP-LTGI 267 Query: 312 LKACRRAVRDSGIELE----EVGAVVMVGGSTRVPRVREAVGALFGRTPLTSIDPDQVVA 367 + A A+ EL E G +V+ GG + + + G + + DP VA Sbjct: 268 VSAVMVALEQCPPELASDISERG-MVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVA 326 Query: 368 IGAAI 372 G Sbjct: 327 RGGGK 331
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.008 Identities = 20/128 (15%), Positives = 24/128 (18%), Gaps = 1/128 (0%) Query: 174 VSEGQQPEGQALPLEPNATEQAPVAEAQSPVAAVTPAAPATSAAPTAVAPVAPVAAPVAA 233 S Q E A + T AP P P P APV Sbjct: 35 TSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVI 94 Query: 234 APAAPV-APLAAAAPVDAAPAGSAKVHIQFTADCWTQVTDGNGKVLFSAIKRKGDSLELT 292 P P P K A + + + Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA 154 Query: 293 GKPPFAVR 300 P R Sbjct: 155 SGPRALSR 162
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 106 bits (267), Expect = 1e-28 Identities = 82/363 (22%), Positives = 126/363 (34%), Gaps = 74/363 (20%) Query: 1 MRILVTGASGFIGGRFARFALEQGLEVR----------VNGRRAEGVEHLVKRGAQFIPG 50 M+ LVTGA+GFIG ++ LE G +V V+ ++A +E L + G QF Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQAR-LELLAQPGFQFHKI 59 Query: 51 DLGDAELARRLCQ--GVDAVVHCAGAVGTWGRY-----QDFHQGNVVLTENVVEGCIKEH 103 DL D E L + V + RY + N+ N++EGC Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAV--RYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 104 VRRLVHLSSPSVYFTGRSRLDIREDQVPRRFHDHYALTKHLAEQKVFGAQE-FGLEVLAL 162 ++ L++ SS SVY R + D YA TK E +GL L Sbjct: 118 IQHLLYASSSSVYGLNRK-MPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 163 RPRFVT-----GAGDASIFPRLMRMQAKGRVAIIGNGLNKVDFTSVHNLNEALLSAL--- 214 RF T G D ++F M + + G K DFT + ++ EA++ Sbjct: 177 --RFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 215 -------------FAEEQALGQVYNISNGHPLPLWDVVNYVMRRMQLPQVTRYRSPSLAY 261 A A +VYNI N P+ L D + + + + Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ--- 291 Query: 262 GLAALNEAACMLWPGRPQPTLSRTAVRVMSTDFTLDIGRARQYLDYRPQPDVWSALDEFC 321 PG T + D + + + P+ V + F Sbjct: 292 -------------PGDVLETSA-------------DTKALYEVIGFTPETTVKDGVKNFV 325 Query: 322 AWW 324 W+ Sbjct: 326 NWY 328
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.5 bits (74), Expect = 0.002 Identities = 48/269 (17%), Positives = 91/269 (33%), Gaps = 38/269 (14%) Query: 19 TPDDDELLPAHVA-RSRQKAARPRSNGPLWALLGASFIALGGLGWWSFQQITLMEQQLVA 77 D++E LPAH+ + RPR + ++G IA + + +L Sbjct: 35 EKDENEFLPAHLELIETPVSRRPRLVA--YFIMGFLVIAFILSVLGQVEIVATANGKLTH 92 Query: 78 TQESFARISEEAAGRLQAI---------SGKVDASESSSSTGSEALKLQIRQLQASLAEQ 128 + S I ++ I G V ++ ++ LK Q LQA L + Sbjct: 93 SGRS-KEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQT 151 Query: 129 GKQQQGVA---GQAGDLGKRLEQVLADTREQQKAVTELQGQLQAQLKAVNAELAAIKSGQ 185 Q + + +L E + E++ V L ++ Q + + Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEE--VLRLTSLIKEQFSTWQNQKYQKEL-- 207 Query: 186 VDGGKLDGQLKSLSNEVAALKKQGNPSAAIESLEQDVLVLKSQVDNRSATSAGGA----S 241 L E + A I E V KS++D+ S+ A + Sbjct: 208 --------NLDKKRAERLTVL------ARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA 253 Query: 242 VQEFDAFRGQVTRNINTLQSQIQNLQQQI 270 V E + + + +SQ++ ++ +I Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEI 282
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 306 bits (784), Expect = 4e-94 Identities = 204/714 (28%), Positives = 317/714 (44%), Gaps = 57/714 (7%) Query: 66 SGSTVTVNGGQVTASGAQTGISMREGTQASLDGATVTAGASGYGVGAINASTIVAKGSTI 125 V V ASGA +S+ ++ +LDG +T G + GV A+ + + + +TI Sbjct: 202 VLRDTNVTA--VPASGAPAAVSVLGASELTLDGGHITGGRAA-GVAAMQGAVVHLQRATI 258 Query: 126 SGG---SGAALSHGSVLELIGGTLTGTRRMGAYLNGSTLIA-SGGTVISGKTNGLNVTQD 181 G +G A+ G+V G G L+G + SG +V ++ Sbjct: 259 RRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELG 318 Query: 182 LAADGGGGSQVRLEGSTVMSETGSAILVRKATDGTTGTATIEVNNGSQLIGGNGTILEVT 241 A G G++V + G ++ + G+ I A A + + + +L Sbjct: 319 AAIRVGRGARVTVSGGSLSAPHGNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRV 378 Query: 242 GGMTADFA-ADNSQLSGDVVVDASSSA--------NLVLRNNASLRGNLVNVQSLALQSG 292 + GD+V S ++ L + A G V SL++ Sbjct: 379 LPEPVKLTLTGGADAQGDIVATELPSIPGTSIGPLDVALASQARWTGATRAVDSLSID-N 437 Query: 293 GRWTLTQDAQVGDLSLD-DGTVDFTHRDTTPGFKTLTLDSLVGSGVFVMGIDLASGTGDL 351 W +T ++ VG L L DG+VDF FK LT+++L GSG+F M + G D Sbjct: 438 ATWVMTDNSNVGALRLASDGSVDFQQPAEAGRFKVLTVNTLAGSGLFRMNVFADLGLSDK 497 Query: 352 LKITGTAEGNHQLSIASTGVDPVEGQAPHRIVETGGGDATFGLLH---DIDFGTFLYTLE 408 L + A G H+L + ++G +P + G ATF L + +D GT+ Y L Sbjct: 498 LVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVDIGTYRYRL- 556 Query: 409 KGDGEDNWYL--------------------------------KQKPGNVLTPSARAVL-- 434 +G W L + G L+ +A A + Sbjct: 557 AANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNT 616 Query: 435 GMFSAAPTVWYGELSSLRSRMGELRL-GQGQGLWMRGYGNRYNLSAGSAVAYQQDQNGVN 493 G A T+WY E ++L R+GELRL G W RG+ R L + + Q G Sbjct: 617 GGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFE 676 Query: 494 FGADGALPDYDGRWLLGVMGGYSESDLDYSLGSSGKIKSYYVGAYSTWMAESGYYIDAVL 553 GAD A+ GRW LG + GY+ D ++ G S +VG Y+T++A+SG+Y+DA L Sbjct: 677 LGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVHVGGYATYIADSGFYLDATL 736 Query: 554 KYNRFRNRNDVVMSDGRKTKGEYHNDGLGASVEIGRHIKLDDGWYVEPFTQLSTLWVDGD 613 + +R N V SDG KG+Y G+GAS+E GR DGW++EP +L+ G Sbjct: 737 RASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGG 796 Query: 614 SYTLDNGLRAESNGANSVLGKVGAQVGRNLALDGGTLLQPYLKVAAAHEFINDNRVKVND 673 +Y NGLR G +SVLG++G +VG+ + L GG +QPY+K + EF V N Sbjct: 797 AYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNG 856 Query: 674 NRFTNDLSGTRGEVAVGVVAQVSDVLQLHGEFQYSNGEHIEQPYGVNLGLRYNF 727 +L GTR E+ +G+ A + L+ ++YS G + P+ + G RY++ Sbjct: 857 IAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 3e-20 Identities = 34/127 (26%), Positives = 60/127 (47%) Query: 2 RVLLVEDHLQLAESVAQALKSQGLTVDVLHDGVAADLALASEDYAVAVLDVGLPRLDGFE 61 +L+ +D + + QAL G V + + +A+ D + V DV +P + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLARLRGRGKTLPVLMLTARSDVKDRVHGLNLGADDYLAKPFELTELEARVKALLRRSVL 121 +L R++ LPVL+++A++ + GA DYL KPF+LTEL + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 GGERQQR 128 + + Sbjct: 125 RPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.012 Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 26/95 (27%) Query: 365 LLSNLVDNALAH----TPPGGDVVLRVLAP---AVLEVEDDGPGIPEDERERVFERFYRR 417 L+ LV+N + H P GG ++L+ LEVE+ G ++ +E Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------- 309 Query: 418 SAQGSGLGLAIVGEICRAHLAQISLHDGERGGLKV 452 +G GL V E ++ + G +K+ Sbjct: 310 ---STGTGLQNVRE-------RLQMLYGTEAQIKL 334
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 26.1 bits (57), Expect = 0.014 Identities = 9/40 (22%), Positives = 16/40 (40%), Gaps = 1/40 (2%) Query: 38 EADRELYRRLLTCEDQDMFGWFMERSES-EDPELQRMVRI 76 E DRE Y + W + R+ + E L + + + Sbjct: 115 ELDRENYSYAFVSGPNTEYLWLLSRTPTVERGILDKFIEM 154
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 117 bits (296), Expect = 3e-31 Identities = 96/357 (26%), Positives = 151/357 (42%), Gaps = 61/357 (17%) Query: 17 LGIDLGTTNSLIAVWQDGEARLIPNAVGEVLT-PSVVSVDDDGS------ILVGQAARSR 69 L IDLGT N+LI V G VL PSVV++ D + VG A+ Sbjct: 13 LSIDLGTANTLIYV----------KGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQM 62 Query: 70 LTTHPERTAAAFKRFMGSDKRYTLGEHRFTPEELSALVLGALKQDAEAYLGCAVSEAVIS 129 L P AA G + F E++ + + ++ ++ Sbjct: 63 LGRTPGNIAAIRPMKDGVIADF------FVTEKMLQHFIKQVHSNS---FMRPSPRVLVC 113 Query: 130 VPAYFSDEQRKRTVFAAELAGLKVQRLINEPTAAAMAYGLHEQKFERTLVFDLGGGTFDV 189 VP + +R+ +A+ AG + LI EP AAA+ GL + ++V D+GGGT +V Sbjct: 114 VPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEV 173 Query: 190 TVLEYALPLIEVHASTGDNYLGGEDFTEALLQACLRDWNLKAEDLAPQALASLHDAIEQL 249 V+ L + +S +GG+ F EA++ R++ L +A A E++ Sbjct: 174 AVIS--LNGVVYSSSV---RIGGDRFDEAIINYVRRNYGS----LIGEATA------ERI 218 Query: 250 KRE-----PGEGSRVLDWH--DGAQ--PREWRLD-DLKLQAIWAPLLTRVRAPIEQALRD 299 K E PG+ R ++ + A+ PR + L+ + L+A+ PL V A + AL Sbjct: 219 KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSA-VMVALEQ 277 Query: 300 ARLSPRELDS------LVLVGGATRMPQVQQLVAKLFGRLPYRHLDPDTIVALGAAS 350 P EL S +VL GG + + +L+ + G DP T VA G Sbjct: 278 ---CPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 477 bits (1229), Expect = e-169 Identities = 160/478 (33%), Positives = 236/478 (49%), Gaps = 50/478 (10%) Query: 7 TVLIVEDDPHVLLGCQQALALEDIACEGVGSAEQALERIGDDFAGIVVSDIRLPGIDGLE 66 T+L+ +DD + QAL+ +A I +VV+D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 LLNRLKARDRSLPVVLITGHGDIDMAVGAMRNGAYDFMEKPFSPERLVEVVRRALEQRGL 126 LL R+K LPV++++ A+ A GAYD++ KPF L+ ++ RAL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 127 SREVFALRRQLAEQSSLEGRIIGRSPAMEQLRELIANVADTSANVLIEGETGTGKELVAR 186 + + Q + ++GRS AM+++ ++A + T ++I GE+GTGKELVAR Sbjct: 125 RPS----KLEDDSQDGMP--LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 187 CLHDFSRRQGQPFVALNCGGLPENLFESEIFGHEANAFTGAGKRRIGKIEHANGGTLFLD 246 LHD+ +R+ PFVA+N +P +L ESE+FGHE AFTGA R G+ E A GGTLFLD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 247 EVESMPINLQIKLLRVLQERTLERLGSNQSIPVDCRVIAATKSDLAVLGQSGQFRSDLYY 306 E+ MP++ Q +LLRVLQ+ +G I D R++AAT DL G FR DLYY Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 307 RLNVVTLELPPLRERREDILQLFEHFLQQSALRFDREAPTLDSQTLSQLMAHDWPGNVRE 366 RLNVV L LPPLR+R EDI L HF+QQ+ + + D + L + AH WPGNVRE Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 367 LRNVAERHAL-------------------------------------------GLPAFKK 383 L N+ R + + Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 384 GTSAGASQGLGFAEAVEAFERNLLSDALQRSGGNLSQASQELGMAKTTLFDKVKKYGL 441 + + E L+ AL + GN +A+ LG+ + TL K+++ G+ Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.3 bits (115), Expect = 3e-08 Identities = 34/133 (25%), Positives = 68/133 (51%), Gaps = 3/133 (2%) Query: 56 LIWGLAQPFTGALADRLGAAKVVVIGGILYTAGLVMMGMADSAWSLSLSAGLLIGIGLSG 115 L + + G L+D+LG ++++ G I+ G V+ + S +SL + A + G G + Sbjct: 60 LTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AA 118 Query: 116 TSFSVILGVVGRAVPPEKRSMAMGIASAAGSFGQFAMLPGTLGLI-QWLGWSAALLVLGL 174 ++++ VV R +P E R A G+ + + G+ + P G+I ++ WS LL+ + Sbjct: 119 AFPALVMVVVARYIPKENRGKAFGLIGSIVAMGE-GVGPAIGGMIAHYIHWSYLLLIPMI 177 Query: 175 MVALIVPFVGLLR 187 + + + LL+ Sbjct: 178 TIITVPFLMKLLK 190 Score = 31.0 bits (70), Expect = 0.008 Identities = 20/138 (14%), Positives = 45/138 (32%), Gaps = 12/138 (8%) Query: 12 LVGAALILALSLGVRHGFGLFLAPMSAEFGWGREVFAFAIALQNLIWGLAQPFTGALADR 71 + G ++ + H V F + +I+G G L DR Sbjct: 272 VAGFVSMVPYMMKDVHQLSTAEIG---------SVIIFPGTMSVIIFG---YIGGILVDR 319 Query: 72 LGAAKVVVIGGILYTAGLVMMGMADSAWSLSLSAGLLIGIGLSGTSFSVILGVVGRAVPP 131 G V+ IG + + S ++ ++ +G + +VI +V ++ Sbjct: 320 RGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQ 379 Query: 132 EKRSMAMGIASAAGSFGQ 149 ++ M + + + Sbjct: 380 QEAGAGMSLLNFTSFLSE 397
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 118 bits (298), Expect = 9e-39 Identities = 34/89 (38%), Positives = 53/89 (59%), Gaps = 1/89 (1%) Query: 2 TKSELIERIVTHQGLLSSKDVELAIKTMLEQMSQCLATGDRIEIRGFGSFSLHYRAPRVG 61 K +LI + V L+ KD A+ + +S LA G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAK-VAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGQSVSLEGKYVPHFKPGKELRDRV 90 RNP+TG+ + ++ VP FK GK L+D V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 64.4 bits (157), Expect = 1e-13 Identities = 42/234 (17%), Positives = 83/234 (35%), Gaps = 28/234 (11%) Query: 6 TLMITGGTGSFGNAVLKGFLDT--DIAEIRIFSR--DEKKQDDMRKRYASPKLKFYIGDV 61 ++TG G G V K L+ + I + D + + A P +F+ D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 62 RDFQSV--LNATRGVDYIFHAAALKQVPSCEFHPMEAVKTNVVGTDNVLEAAIQNEVKRV 119 D + + L A+ + +F + V +P +N+ G N+LE N+++ + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 120 VCLST---------------DKAVYPINAMGISKAMMEKVMVAKSRNVDPLKTVICGTRY 164 + S+ D +P++ +K E + S L G R+ Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG-LPAT--GLRF 178 Query: 165 GNVMASRGS---VIPLFVDQVRAGKPLSI-TDPNMTRFMMTLADAVDLVLYAFE 214 V G + F + GK + + M R + D + ++ + Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQD 232
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 62.1 bits (151), Expect = 5e-13 Identities = 52/261 (19%), Positives = 88/261 (33%), Gaps = 55/261 (21%) Query: 1 MNVLITGADGFIGKNLLVHLQE------------------LKDIAVATFTRDN------D 36 M L+TGA GFIG ++ L E LK + + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 37 IAALPA-----KVADADFIFHL---AGINR-PQDPKEFTSGNVDLTRALAEAVRATGRSV 87 +A + +F + ++P + N+ + E R Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ- 119 Query: 88 PLLYTSSTQAALDN----------------VYGASKRGAEKVLQDLHAQTGSPVHLFRLP 131 LLY SS+ N +Y A+K+ E + G P R Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 132 NVFGKWARPNYNSAVATFCHNIARDLPIQI-NDPQARVSLVYIDDVVRCFLQVMRGEHID 190 V+G W RP+ A+ F + I + N + + YIDD+ +++ + I Sbjct: 180 TVYGPWGRPDM--ALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ--DVIP 235 Query: 191 QVEPQYDVSVGEIASYLQAFR 211 + Q+ V G A+ + +R Sbjct: 236 HADTQWTVETGTPAASIAPYR 256
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 2e-07 Identities = 36/206 (17%), Positives = 71/206 (34%), Gaps = 15/206 (7%) Query: 317 VDALQGEALAHHLRLQLQETLNSLRHAEVRYQNSELALHDQLARAAKAEGLQAKSQASAE 376 + AL EA L+ Q +L R + RYQ ++ K S E Sbjct: 127 LTALGAEAD----TLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEE 182 Query: 377 VYQVQLQQVTAELLTAFKEQQRLQLDVEALRHQQVSSTQMLELERARGDTLLQRVSEQES 436 + + T ++ + +L+++ R ++++ + R+ + S Sbjct: 183 EVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS 242 Query: 437 LAEALAGERDALM---RERESLEAELQGALDGVAQAERAELQRQAEILRFQ--------D 485 L A + A++ + EL+ + Q E L + E D Sbjct: 243 LLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD 302 Query: 486 ELHQCNLHVADLESRLAGGEQRTEMT 511 +L Q ++ L LA E+R + + Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQAS 328 Score = 31.3 bits (71), Expect = 0.016 Identities = 17/108 (15%), Positives = 32/108 (29%), Gaps = 3/108 (2%) Query: 456 EAELQGALDGVAQAERAELQRQAEILRFQDELHQCNLHVADLESRLAGGEQRTEMTA--- 512 EA+ + QA + + Q + + + E+ +T+ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 513 SQLKELVQHSAQLESELRRSQASLLTSLAAAEHLSLQANAHQERIQAL 560 Q Q E L + +A LT LA + + R+ Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 111 bits (278), Expect = 4e-30 Identities = 78/333 (23%), Positives = 128/333 (38%), Gaps = 25/333 (7%) Query: 3 KAIVTGVTGQDGAYLAQLLLDKGYCVYG-----TYRRTSSVNFWRIEELGIAQHPNLHLV 57 K +VTG G G ++++ LL+ G+ V G Y S + R+E L P Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVS-LKQARLELLA---QPGFQFH 57 Query: 58 EYDLTDLSASIRLLQTTEATEVYNLAAQSFVGVSFEQPVTTAEITGVGAVNLLEAIRIVN 117 + DL D L + V+ + V S E P A+ G +N+LE R Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 118 PKVRFYQASTSEMFGKVQAIPQVETTPF-YPRSPYGVAKLYAHWMTINYRESYGIFGTSG 176 + AS+S ++G + +P +P S Y K M Y YG+ T Sbjct: 118 IQ-HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 177 ILFNHESPLRGR-EFVTRKITDSVAKIQMGK-LDVLELGNLDAKRDWGFAKEYVEGMWRM 234 F P GR + K T ++ + GK +DV G + KRD+ + + E + R+ Sbjct: 177 RFFTVYGP-WGRPDMALFKFTKAMLE---GKSIDVYNYGKM--KRDFTYIDDIAEAIIRL 230 Query: 235 LQVDEPDTFVLATNRTETVRDFVSLAFKAVDVNLEWTGSGEQEQGVDAVSGNVVVSINPK 294 V ET S+A V N+ + E + A+ + + Sbjct: 231 QDVIPHAD---TQWTVETGTPAASIAPYRV-YNIGNSSPVELMDYIQALEDALGIEAKKN 286 Query: 295 F--YRPAEVELLIGDPAKAKAKLGWEPKTTLEE 325 +P +V D +G+ P+TT+++ Sbjct: 287 MLPLQPGDVLETSADTKALYEVIGFTPETTVKD 319
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 146 bits (369), Expect = 2e-43 Identities = 79/331 (23%), Positives = 131/331 (39%), Gaps = 43/331 (12%) Query: 3 KVLLTGANGFVGRVLRTYLDSAGWSVIGTSS----------SHSAPAHAED----ILLDI 48 K L+TGA GF+G + L AG V+G + A+ +D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 49 TDADALASVVKRVQPDAVVHLAAVTHVPTSLREPQLTWRTNVLGTVNLLEAVKHHAPQAF 108 D + + + + V V SL P +N+ G +N+LE +H+ Q Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 109 VLFVSSSEVYGEAFKAGVALDEQARCLPMNPYAASKLAAEL-ACQQHWRQGFPGAIARPF 167 + + SSS VYG K + D+ P++ YAA+K A EL A G P R F Sbjct: 122 L-YASSSSVYGLNRKMPFSTDDSVD-HPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 168 NHIGPGQSPDFVTASFARQVANIEAGLQPPVMRVGNLEACRDFLDVRDVCKAYVQLL--- 224 GP PD F + + G V G ++ RDF + D+ +A ++L Sbjct: 180 TVYGPWGRPDMALFKFTK---AMLEGKSIDVYNYGKMK--RDFTYIDDIAEAIIRLQDVI 234 Query: 225 --------------ALSDFPVQNRVFNIASGHATKIRDVLDVMLQQSVVDIDIQLDPERL 270 A S P RV+NI + ++ D + + ++ + P L Sbjct: 235 PHADTQWTVETGTPAASIAPY--RVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP--L 290 Query: 271 RPSDIPFAVGDSRHVLDATGWRPGYALSDTL 301 +P D+ D++ + + G+ P + D + Sbjct: 291 QPGDVLETSADTKALYEVIGFTPETTVKDGV 321
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.4 bits (214), Expect = 4e-21 Identities = 59/348 (16%), Positives = 118/348 (33%), Gaps = 43/348 (12%) Query: 14 KVFLTGHTGFKGSWLSLWLQGMGAEVKGF-ALAPPTTPSLFE--QAQVERGMQASQIGDI 70 K +TG GF G +S L G +V G L SL + + + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 71 RDLQAITESMVAFAPDILIHMAAQPLVRLSYREPVETYATNVMGTVHVLEAARQCPSLRA 130 D + +T+ + + + + VR S P +N+ G +++LE R ++ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN-KIQH 120 Query: 131 IVNVTTDKCYENQEWEWGYRENEPMGGHD-------PYSNSKGCVELITSAYRNSFFNSP 183 ++ ++ Y G P D Y+ +K EL+ Y + + P Sbjct: 121 LLYASSSSVY-------GLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTY-SHLYGLP 172 Query: 184 GAAALASARAGNVIGGGDWAE-DRLIPDILRAVEQGQAVVVRNP-KATRPWQHVLEPLSG 241 R V G W D + +A+ +G+++ V N K R + ++ + Sbjct: 173 ----ATGLRFFTVY--GPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEA 226 Query: 242 YLVLAQHLWEQGPAFAEG-------------WNFGPRDEDARPVEWILDHMVQVWGEGAS 288 + L + + +N G + + + + G A Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIG--NSSPVELMDYIQALEDALGIEAK 284 Query: 289 WRLDEAPQPHEARYLKLDISKARTHLKWEPTWSLDTTLTRIVDWHRAW 336 + QP + D + + P ++ + V+W+R + Sbjct: 285 KNMLP-LQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 36.3 bits (84), Expect = 1e-04 Identities = 42/222 (18%), Positives = 69/222 (31%), Gaps = 41/222 (18%) Query: 109 RYIYLSSGAAYGSHFAAPVTETSLASFPIKALQPQDWYGAAKFQAE---CRHRALPEASI 165 +Y SS + YG + P + P Y A K E + L Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVD------HPVSLYAATKKANELMAHTYSHLYGLPA 173 Query: 166 VDVRVFSYFSHRQAPKARFFLSDILRALHSGEVLQVAAD-DMFRDYLTPADFLQLIERIL 224 +R F+ + P F +A+ G+ + V M RD+ D + I R+ Sbjct: 174 TGLRFFTVYGPWGRPDMALFK--FTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 225 KAPPCNDA-------VDCYSLA-----------PVGKFDLLAALAEQFGLRFAVTGDQAR 266 P D S+A PV D + AL + G+ A+ Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE-------AK 284 Query: 267 VN----ATGPKAHYYSRNRKAEQLFGYVPGDSSLSGVLREIR 304 N G + + ++ G+ P + GV + Sbjct: 285 KNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVN 326
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 29.8 bits (67), Expect = 0.013 Identities = 22/90 (24%), Positives = 35/90 (38%), Gaps = 11/90 (12%) Query: 163 AGQIA-KLKGCRVVGIAGGAQKCQY-LLDELGFDGVIDYKTEDVLAGLKRECPNGVDVYF 220 AG IA VVG+A A +L++ G + ++ G+ VD+ Sbjct: 91 AGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQ-----YDWIIQGIYYAIEQKVDIIS 145 Query: 221 DNVGGDILDAVLSRLNFKAR----VVICGA 246 ++GG L KA +V+C A Sbjct: 146 MSLGGPEDVPELHEAVKKAVASQILVMCAA 175
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 121 bits (305), Expect = 1e-35 Identities = 72/251 (28%), Positives = 114/251 (45%), Gaps = 8/251 (3%) Query: 7 GQVALVTGGAAGIGRATAQAFAAEGLKVVVADRDATGGETTVALIRQAGGEALFVACDVT 66 G++A +TG A GIG A A+ A++G + D + E V+ ++ A DV Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 67 RDDDVRQLHEQVITAYGRLDYAFNNAGIEIEKGRLAEGSEAEFDAIMGVNVKGVWLCMKY 126 + ++ ++ G +D N AG+ + G + S+ E++A VN GV+ + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 127 QLPLLLAQGGGAIVNTASVAGLSAAPKMSIYAASKHAVIGLTKSAAIEYAKKGIRVNAVC 186 ++ + G+IV S M+ YA+SK A + TK +E A+ IR N V Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 187 PAVIDTDMFRR----AYEADPRKAEFAAAMH---PVGRIGKVEEIASAVLYLCSDGAAFT 239 P +TDM A+ P+ ++ K +IA AVL+L S A Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 240 TGHSLTVDGGA 250 T H+L VDGGA Sbjct: 247 TMHNLCVDGGA 257
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 59.5 bits (144), Expect = 6e-12 Identities = 66/271 (24%), Positives = 106/271 (39%), Gaps = 28/271 (10%) Query: 34 LSGQGAAATAVAFSGYVLGVLPVLLALGGLADRVGRRPLILVALALSMVATLLMLLAPSL 93 S A + + Y L LG L+DR GRRP++LV+LA + V +M AP L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 94 QMLGLARLFLGLGTGLASATATAYMSELMAPDADSHAATWVTASTSLGFGLGAALTSLFL 153 +L + R+ G+ TG A A AY++++ D + +++A G G L L Sbjct: 97 WVLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 154 LRGPTLTPGSFHLQLALAALALLLV-WRLPDPRPAQCSAMLRLPCYPAGSLAYGLAI-LL 211 P F AL L L + LP+ + + R P S + + ++ Sbjct: 156 GFSPHA---PFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 212 AWACVGLVIALLPGILRQHGLSAW-------------------SGFSTFCVISCGLLFQP 252 A I L G Q + W + F ++ ++ P Sbjct: 213 AALMAVFFIMQLVG---QVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 253 LARRLASAQATLLGLLILPCSYALLAWGADS 283 +A RL +A +LG++ Y LLA+ Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRG 300
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 414 bits (1066), Expect = e-144 Identities = 92/429 (21%), Positives = 173/429 (40%), Gaps = 4/429 (0%) Query: 5 TRDARFHVRLGWLLTLVGFGGFMAWASLAPLDQGVPVQGTVVVSGKRKAVQSMAAGVVSR 64 T +R + + + F + L ++ G + SG+ K ++ + +V Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAF-ILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKE 109 Query: 65 ILVSEGQLVRQGEPLFRLDRTQVQADVDALQAQYRMTRAALARWQSERDNLGQVQFPAEL 124 I+V EG+ VR+G+ L +L +AD Q+ R R+Q ++ + P Sbjct: 110 IIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELK 169 Query: 125 LEDSDARLALI---VEGQRQLFDSRRQAQAREQGALAASIDGSQAQLTGMRRARSDLQAQ 181 L D + V L + ++ ++D +A+ + + + Sbjct: 170 LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENL 229 Query: 182 ADSLREQLDSLRPLAGDGYIPRNRVLEYQRQLSQVQRDLAQNAGESARLEQVIVEARLNL 241 + + +LD L I ++ VLE + + + +L + ++E I+ A+ Sbjct: 230 SRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEY 289 Query: 242 QQRREEYQKEVRTQLAEAQVKAATLEQQLNSAHFELQHSEILAPADGVAVNLGVHTEGAV 301 Q + ++ E+ +L + L +L Q S I AP L VHTEG V Sbjct: 290 QLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 302 VRAGDTLLEIVPQGTALEVEGRLPVNLVDKVAPQLPVDILFTAFNQNRTPRVTGEVALVS 361 V +TL+ IVP+ LEV + + + I AF R + G+V ++ Sbjct: 350 VTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409 Query: 362 ADQLIDERSGQPYYVLRSTVSEEALARLQGLAIRPGMPAELFVRTGERSLLNYLFKPLLD 421 D + D+R G + V+ S + + + GM ++TG RS+++YL PL + Sbjct: 410 LDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEE 469 Query: 422 RAGTALTEQ 430 +L E+ Sbjct: 470 SVTESLRER 478
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.1 bits (130), Expect = 4e-10 Identities = 74/370 (20%), Positives = 134/370 (36%), Gaps = 16/370 (4%) Query: 30 PLLHSIAQQFGLSTASAGTIVIAAQLSYGAGLLLLAPLG----DLFEQRRLIVTMVLIAT 85 P+L + + S I L Y AP+ D F +R +++ + A Sbjct: 26 PVLPGLLRDLVHSNDVTAHYGILLAL-YALMQFACAPVLGALSDRFGRRPVLLVSLAGAA 84 Query: 86 AGLVISACAPSLPWLLLGTALTGLSSVVAQVLVPMAAALSAPEQRGRAVGTLMSGLLLGI 145 I A AP L L +G + G++ V A ++ ++R R G + + G+ Sbjct: 85 VDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGM 144 Query: 146 LLARTAAGFMAELGGWRSIYVLAAVLMAISALALYRSLPQHHSHAGLKYPALIGSVFRLF 205 + G M + + AA L ++ L LP+ H + F Sbjct: 145 VAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASF 203 Query: 206 VEEPVLRLRSLLGLLAFSLFALFWTPLAF--LLSNAPYHYSDAVIGL-FGLAGAIGALA- 261 + + + L + F + + P A + +H+ IG+ G + +LA Sbjct: 204 RWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQ 263 Query: 262 ANWAGRLADRGKGPLGTTVGLVALLLSWVPLGFAQQSLVALLVGVLLLDLAVQLVHVSNQ 321 A G +A R +G++A ++ L FA + +A + VLL + + + Sbjct: 264 AMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAM 323 Query: 322 NAVIVLRPEARTRLNAGYITCYFIGGALGSLLGTQLFEVH-----GWDGIVVAGLVIGAL 376 + V E + +L + +G LL T ++ GW I A L + L Sbjct: 324 LSRQV-DEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCL 382 Query: 377 ALVVWGLAER 386 + GL Sbjct: 383 PALRRGLWSG 392
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 111 bits (279), Expect = 8e-32 Identities = 80/256 (31%), Positives = 120/256 (46%), Gaps = 21/256 (8%) Query: 7 LTGKVALVQGGSRGIGAAIVRRLARDGAKVAFTYVSSNASAEALAGEINNAGGQALALRA 66 + GK+A + G ++GIG A+ R LA GA +A + E + + A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 67 DSADIQAVQQAVADTAKAFGGLDILVNNAGVLAVAPVAEFDLADFDRLLAINVRSVFVAT 126 D D A+ + A + G +DILVN AGVL + +++ ++N VF A+ Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 127 QAAVKHM--GKGGRIINIGSTNAERMPFAGGAPYAMSKSALVGLTKGLARDLGPQGITVN 184 ++ K+M + G I+ +GS N +P A YA SK+A V TK L +L I N Sbjct: 125 RSVSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 185 NVQPGPVDTDMN--------------PASGEFAESLIPLMAIGRYGQADEIASFVAYLAG 230 V PG +TDM S E ++ IPL + + +IA V +L Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAK---PSDIADAVLFLVS 240 Query: 231 PEAGYITGASLLADGG 246 +AG+IT +L DGG Sbjct: 241 GQAGHITMHNLCVDGG 256
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 78.4 bits (193), Expect = 2e-19 Identities = 55/250 (22%), Positives = 114/250 (45%), Gaps = 9/250 (3%) Query: 8 NWVALNTIVYREVRRFLRIWPQTLLPPAITMVLYFVIFGNLIGRQIGDMGGFTYMEYIVP 67 NW+A + R + + +LL ++Y G +G +G +GG +Y ++ Sbjct: 15 NWIA---VWRRNYIAWKKAALASLLGHLAEPLIYLFGLGAGLGVMVGRVGGVSYTAFLAA 71 Query: 68 GLIMMSVITNS-YGNVVSSFFGSKFQRSIEELMVSPVSPHTILVGYVLGGVLRGLAVGVI 126 G++ S +T + + + ++F + QR+ E ++ + + I++G + + G Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 127 VTILSLFFTHLQVHHLGVTLVVVLLTATIFSLLGFVNAVFARNFDDISIIPTFVLTPLTY 186 + +++ + Q L L V+ LT F+ LG V A ++D T V+TP+ + Sbjct: 132 IGVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILF 191 Query: 187 LGGVFYSINLLPPFWQTVSLANPVLHMVNSFRYGILGVSDISIGTAISFMLVATALLY-- 244 L G + ++ LP +QT + P+ H ++ R +LG + + + + + + + Sbjct: 192 LSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFL 251 Query: 245 ---LLCVRLL 251 LL RLL Sbjct: 252 STALLRRRLL 261
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.9 bits (75), Expect = 0.005 Identities = 29/133 (21%), Positives = 45/133 (33%), Gaps = 26/133 (19%) Query: 306 PLLMALSGVLLVEPLASLLPGFWLSFAAVAVLVLCFAARLGAWRPW--------QAWTRA 357 P L +G+ +E PG A + L G W + +A Sbjct: 813 PRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQA 872 Query: 358 QWVIAVGLLPVLLALGLPV-SLSAPLANLLAVPWLSWGVLPLALLGTALLPVPGLGEVML 416 ++A+ + V L L S S P++ +L V+PL ++G LL Sbjct: 873 PALVAISFVVVFLCLAALYESWSIPVSVML--------VVPLGIVG-VLL--------AA 915 Query: 417 WLAGLSLDGLFAV 429 L D F V Sbjct: 916 TLFNQKNDVYFMV 928
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 63.2 bits (153), Expect = 5e-12 Identities = 57/420 (13%), Positives = 111/420 (26%), Gaps = 54/420 (12%) Query: 494 NNQSSYEIASAETEEAPQPTATRTLVRQEAAVKTAPARANAPVPATAEEQPAPAAPVAAP 553 N Y++ + E E+ Q + T P A VP+ A AP Sbjct: 973 NVNGRYDLYNPEVEKRNQTV--------DTTNITTPNNIQADVPSVPSNNEEIARVDEAP 1024 Query: 554 AAEPSLFKGLVKSLVSLFAGKEEPAAAPAAATEKPATERSPRNEERRNGRQQSRNRNGRR 613 P+ A P+ TE A ++ Q + + Sbjct: 1025 VPPPA-------------------PATPSETTETVAENSKQESKTVEKNEQDATETTAQN 1065 Query: 614 EEDRKPREERAPREERQPREERAPREERAPREERQPRQPREDRRGNREERVRELREPLDA 673 E K + + ++ E +E Q + +E +EE+ + E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSET----KETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 674 ATTAREERAPREERAPREERVAREERAPREERAPREERAPREERAPREERAPREERAARE 733 + +P++E+ + E + +E + E+ +E Sbjct: 1122 VPKVTSQVSPKQEQ-SETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS---- 1176 Query: 734 ERAPREERAPREERAPREERAPREERAPREERAPRDERQLRPEVQAAEQAVELAEEQLPN 793 + + P + V P Sbjct: 1177 -SNVEQP----VTESTTVNTGNSVVENPENT-----------TPATTQPTVNSESSNKPK 1220 Query: 794 EELLQDEQEGADGERPRRRSRGQRRRSNRRER-QRNANGELIDGGDEDAGEERPQQHQAT 852 + + P S R + N N L D + + Sbjct: 1221 NRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVS 1280 Query: 853 ELGAELAAGTAVIAAVATSNISADAEAQANQQAERASAAVAETQVQITEVVAEQVAIAPV 912 + ++L V SN S + ++ Q R S+ +TQ+ + ++ V + V Sbjct: 1281 QHISQLEMNNEGQYNVWVSNTS-MNKNYSSSQYRRFSSKSTQTQLGWDQTISNNVQLGGV 1339 Score = 50.4 bits (120), Expect = 4e-08 Identities = 53/303 (17%), Positives = 86/303 (28%), Gaps = 40/303 (13%) Query: 775 PEVQAAEQAVELAEEQLPNEELLQDEQEGADGERPRRRSRGQRRRSNRRERQRNANGELI 834 PEV+ Q V+ PN + Q + R + A Sbjct: 983 PEVEKRNQTVDTTNITTPN-----NIQADVPSVPSNNE---EIARVDEAPVPPPAPATPS 1034 Query: 835 DGGDEDAGEERPQQHQATELGAELAAGTAVIAAVATSNISADAEAQANQQAERASAAVAE 894 + E E Q+ + E + A T N EA++N +A + VA+ Sbjct: 1035 ETT-ETVAENSKQESKTVEKNEQDATETT------AQNREVAKEAKSNVKANTQTNEVAQ 1087 Query: 895 TQVQITEVVAEQVAIAPVVEQPVSEPVVAAEPSIEPVVEVAPQPVVEEAAAEQPAAVVEA 954 + + E + VE+ V + P V P E++ QP A E Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQA--EP 1145 Query: 955 AVEPAAVVEAPVVEAGEIEKAPVAEAVEAQAPVAEQP------APVVEAVEAQPEAVEAP 1008 A E V ++ A + + + EQP +V PE Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205 Query: 1009 VAEPAPAVVAEEAPVEPSTIMLPNGRAPNDPREVRRRKREAEAAAAALAAAQATPAEALE 1068 +P N + N P+ RR + A + + Sbjct: 1206 TTQPT-----------------VNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Query: 1069 TAD 1071 D Sbjct: 1249 LCD 1251
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 38.4 bits (89), Expect = 1e-05 Identities = 22/121 (18%), Positives = 30/121 (24%), Gaps = 10/121 (8%) Query: 174 PKPKKPEKTEPAAEPK---VEKPAADLGLPEPAPAALAPAPQSAAPVAESVAETPVPTPV 230 +P PA V+ P + PEP P + P+ A V E P P P Sbjct: 47 AQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 106 Query: 231 AAAAAPAPVAAPAAPVPASEAPAAPVVDDSKGSQPIAPPVEPTPIQVQQEAPAAEQVPAP 290 P +P P P + + P Sbjct: 107 PVKKVEQPKRDVKPVESRPASPFENT-------APARPTSSTATAATSKPVTSVASGPRA 159 Query: 291 L 291 L Sbjct: 160 L 160 Score = 33.0 bits (75), Expect = 0.001 Identities = 21/89 (23%), Positives = 28/89 (31%), Gaps = 2/89 (2%) Query: 188 PKVEKPAADLGLPEPAPAALAPAPQSAAPVAESVAETPVPTPVAAAAAPAPVAAPAAPVP 247 ++ PA + + APA L P P V P P P+ APV Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 100 Query: 248 ASEAPAAPVVDDSKGSQPIAPPVEPTPIQ 276 P V + + PVE P Sbjct: 101 --PKPKPKPVKKVEQPKRDVKPVESRPAS 127 Score = 32.3 bits (73), Expect = 0.002 Identities = 19/97 (19%), Positives = 31/97 (31%) Query: 183 EPAAEPKVEKPAADLGLPEPAPAALAPAPQSAAPVAESVAETPVPTPVAAAAAPAPVAAP 242 EP EP E P + E P P+ V + + A+ A Sbjct: 77 EPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPAR 136 Query: 243 AAPVPASEAPAAPVVDDSKGSQPIAPPVEPTPIQVQQ 279 A+ A + PV + G + ++ P + Q Sbjct: 137 PTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQA 173
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 137 bits (346), Expect = 1e-41 Identities = 81/258 (31%), Positives = 124/258 (48%), Gaps = 9/258 (3%) Query: 2 KRFANKTVLVTGGSKGIGRAICCAFASQGASVIFTYAHDSVSAEALCEEIRERGGEASAI 61 K K +TG ++GIG A+ ASQGA + ++ E + ++ A A Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 62 RIDHTSPDSARYIFDRAVWVDNKIDVLVNNVGIFHRASFMSITAAQYDSVLEANLKVPFF 121 D + I R ID+LVN G+ S++ ++++ N F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 122 LCQLVARLMVDQKNSGCIVNVSSLSAVLSRSCMTHYQCSKAALTALSRSLAMELGEYGIR 181 + V++ M+D++ SG IV V S A + R+ M Y SKAA ++ L +EL EY IR Sbjct: 123 ASRSVSKYMMDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 VNTISPGLTATDANRTQWEGDNSAWQ-------SRSAGIPLRRAGVPDDHAGAVVFLASD 234 N +SPG T TD + W +N A Q + GIPL++ P D A AV+FL S Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 235 EARWITGADIVIDGGMSV 252 +A IT ++ +DGG ++ Sbjct: 242 QAGHITMHNLCVDGGATL 259
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.7 bits (67), Expect = 0.021 Identities = 24/97 (24%), Positives = 35/97 (36%), Gaps = 23/97 (23%) Query: 316 EVGKDTWQTA---------LNEALALGFNQYVIQRYVS------AVTSGFSVATPSGEQA 360 EV TWQTA L E N + ++RY++ A+ G S S E Sbjct: 371 EVAIRTWQTADKMKRQRGRLKEETGDNDN-FRVKRYIAKYTINPAIAHGLSHEIGSLEVG 429 Query: 361 HQCGRVVWGPYVFGQHYLGTLIRAQPIEQSAVINYAQ 397 + V+W P FG ++ + I A Sbjct: 430 KRADLVLWNPAFFG-------VKPDMVLLGGTIAAAP 459
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 2e-04 Identities = 13/55 (23%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 78 IGAIFVHPAYMQQGIGKRLLNYLECLARAFSLEQVRLDATLNAAP---FYRRYGF 129 I I V Y ++G+G LL+ A+ + L+ FY ++ F Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>SSBTLNINHBTR#Streptomyces subtilisin inhibitor signature. Length = 144 Score = 27.9 bits (61), Expect = 0.042 Identities = 26/97 (26%), Positives = 32/97 (32%), Gaps = 8/97 (8%) Query: 79 GGAGAAAPAAAAAPAAAPAAAAADAGEDDPVAAPAARKLAEENGIDLATVAGTGKGGRIT 138 GA A+PA A A AP+A G + A A + T A T G Sbjct: 23 AGASLASPATAPASLYAPSALVLTVGHGESAATAAPLRAV------TLTCAPTASGTHPA 76 Query: 139 KEDVVAAVANKKSAPAAAPAAKPAAAAA--APVVVAA 173 A + P+A A APVVV Sbjct: 77 AAAACAELRAAHGDPSALAAEDSVMCTREYAPVVVTV 113
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 4e-04 Identities = 18/79 (22%), Positives = 29/79 (36%), Gaps = 11/79 (13%) Query: 22 KASEDKAQDAQQHAEQAQEKMGEAQDKMNEAAKENAEAAKDQ---------AEAQQKAAE 72 A+E AQ+ + E +A + NE A+ +E + Q E ++KA Sbjct: 1057 DATETTAQNREVAKEAKSNV--KANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 73 EAAPSTPAPTTAPAEPAKQ 91 E + P KQ Sbjct: 1115 ETEKTQEVPKVTSQVSPKQ 1133 Score = 27.7 bits (61), Expect = 0.007 Identities = 15/54 (27%), Positives = 19/54 (35%), Gaps = 3/54 (5%) Query: 39 QEKMGEAQDKMNEAAKENAEAAKDQAEAQQKAAEEAAPST-PAPTTAPAEPAKQ 91 EK + D N N +A D E A P P APA P++ Sbjct: 985 VEKRNQTVDTTNITTPNNIQA--DVPSVPSNNEEIARVDEAPVPPPAPATPSET 1036
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.3 bits (237), Expect = 6e-25 Identities = 42/159 (26%), Positives = 73/159 (45%), Gaps = 4/159 (2%) Query: 3 QAATLLVIDDEPQIRKFLRISLASQGYKVLEAATGGEGLAQAALNKPDLVVLDLGLPDMD 62 AT+LV DD+ IR L +L+ GY V + A DLVV D+ +PD + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GQQVLRELREWSA-VPVMVLSVRASEVQKVDALDGGANDYVTKPFGIQEFLARV-RALLR 120 +L +++ +PV+V+S + + + + A + GA DY+ KPF + E + + RAL Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 121 QAPQVGNGPSAASFGALVV--DFAFRKVTLDGVEVALTR 157 + + G +V A +++ + T Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTD 160
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.6 bits (95), Expect = 9e-06 Identities = 59/334 (17%), Positives = 107/334 (32%), Gaps = 24/334 (7%) Query: 50 GIIGTAFTLVYAIAGLPLARIADTGSRSRLMGWGLLVWSGLTAVNGMVGSFWSFLLVRMG 109 GI+ + L+ L ++D R ++ L + A+ W + R+ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 110 VGIGEASYAPAANSLIGDLFPAGRRARAMG----IFMLGLPLGLLLAFFTIGAMVQAFDS 165 GI A+ A A + I D+ RAR G F G+ G + +G ++ F S Sbjct: 106 AGITGATGAVAG-AYIADITDGDERARHFGFMSACFGFGMVAGPV-----LGGLMGGF-S 158 Query: 166 WRAPFFIAAVPGVLLALF-IFMIREPARGAAETVATAQAPLDRPLRRVLSVPTFAWLVLA 224 APFF AA L L F++ E +G + R + A L Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAAL--- 215 Query: 225 GLTFNFASYACNSFMVPMLQRYFALPLHDAAVATGMIVGLSGLVGLTLGGWMADKVHQRF 284 + F + + H A G+ + G++ + V R Sbjct: 216 -MAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARL 274 Query: 285 ANGRLVFAALSM-LVATLCTAWALHAGRIELGVFVAVFGVGWLFSYNFYTCVYTAIQDVV 343 R + + + A+A + + G + + + Sbjct: 275 GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVD--EER 332 Query: 344 QPRLRATAMALFFAGLYLLGGGLGPVVVGGLSDH 377 Q +L+ + A L L +GP++ + Sbjct: 333 QGQLQGS-----LAALTSLTSIVGPLLFTAIYAA 361
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 27.5 bits (60), Expect = 0.029 Identities = 22/76 (28%), Positives = 30/76 (39%), Gaps = 3/76 (3%) Query: 28 QVRVQRGCMLVNQQRDAGSQALGRIDLGSAARLDGPAAPVSGVLLAQRPPRLECNPDTPY 87 Q+ +Q +L+ S A G + S + L P PV L + PR P P Sbjct: 107 QMTLQDAKVLLEAALRQESGARGHVSSHSHSALHAPGTPVREGLRSHLDPR---TPPLPP 163 Query: 88 QVRVDGGQHGGVGEVR 103 + R H G GE R Sbjct: 164 RERPHTSGHHGAGEAR 179
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 513 bits (1323), Expect = e-172 Identities = 156/811 (19%), Positives = 275/811 (33%), Gaps = 81/811 (9%) Query: 42 TLYLDLLVNQV----AKAELVPVQQRAG-RLYLASEVLREAGIRLPGEPQGEVALDE--- 93 T +D+ +N G L L G+ + D+ Sbjct: 77 TYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACV 136 Query: 94 -----IPGLHSDYDSQNQRLLLQVPPAWLPDQQVGEHNLYPASDARSSFGALLNYDAYLN 148 I + D QRL L +P A++ ++ G + P LLNY+ N Sbjct: 137 PLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGY--IPPELWDPGINAGLLNYNFSGN 194 Query: 149 DTD--EGGSYLAAWNELRLFDDWGTFSSTGQWRQLFN-GAQAQGRQGFLRYDTTFRYTDE 205 GG+ A+ L+ + G + +N + G + ++ T+ D Sbjct: 195 SVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDI 254 Query: 206 QRLL-TYEAGDLVTGALPWTTSVRVGGLQLSRDFGARPDLITYPLPAFAGEAAVPTSLDL 264 L GD T + + G QL+ D PD P G A + + Sbjct: 255 IPLRSRLTLGDGYTQGDIFD-GINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTI 313 Query: 265 FINGYKSSSTELQPGPYTLTNVPFINGAGEAVVVTTDALGRQVSTTLPFYVTSSLLAKGL 324 NGY ++ + PGP+T+ ++ +G+ V +A G T+P+ L +G Sbjct: 314 KQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGH 373 Query: 325 SDFSVAAGSLRRDYAVRDFAYGPGVASATLRHGVSDYFTLETHAESAESMMLGGLGGNLR 384 + +S+ AG R A ++ P +TL HG+ +T+ + A+ G Sbjct: 374 TRYSITAGEYRSGNAQQE---KPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKN 430 Query: 385 LGTFGVLNAALTQSRFEGD--------------------TGQQVAL-GYQYNSRR-IGFN 422 +G G L+ +TQ+ +G + L GY+Y++ F Sbjct: 431 MGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFA 490 Query: 423 YQRVQRHGDYADLS----------LVDSPFTRLSQRSE-QATLSLNLDRYGSLGMGYFDV 471 R Y + D ++R + Q T++ L R +L + Sbjct: 491 DTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQ 550 Query: 472 R-AGDGTRTRLINLSWSKPLWRNS-SLYLSTNREVGDSQWAVQAQLVIPFELR------- 522 G + + +L S + L + Sbjct: 551 TYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDS 610 Query: 523 ------GTLAFSAERSKDGQDLQRVNYSQAVPVGGGVGYNL--GYATGGN--RDDYRQAD 572 + ++S +G+ + + Y++ GYA GG+ A Sbjct: 611 KSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYAT 670 Query: 573 LTWRLQSVQLQVGAYGSSGEMTRWADASGSLVLMDAGLFAANRIDDAFVVVSTSGYADVP 632 L +R +G S + SG ++ G+ ++D V+V G D Sbjct: 671 LNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAK 730 Query: 633 VRYENQQIGRTDRNGHLLVPYSSGYYRGKYEIDPMDLPADVLAPQVEQRVAVRRGSGYLL 692 V ENQ RTD G+ ++PY++ Y + +D L +V V RG+ Sbjct: 731 V--ENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRA 788 Query: 693 EFPLKRVLAASLVLVDADQQELKLGSRVRHQESGGEAVVGWDGLVYLENLAPHNRLQV-- 750 EF RV L+ + + + L G+ V + S +V +G VYL + ++QV Sbjct: 789 EFKA-RVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKW 847 Query: 751 DKADGGQCQVAFDLPEGQGPIPLIG-PLVCQ 780 + + C + LP L C+ Sbjct: 848 GEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 554 bits (1430), Expect = 0.0 Identities = 302/505 (59%), Positives = 383/505 (75%), Gaps = 6/505 (1%) Query: 5 RSLAAGLALLATLVAHGEPLDWSDEPFHYVAQGESLRDVLANFAANYQGSVVVSDKVRDQ 64 R L L LL++ + + LDW P+ YVA+GESLRD+L +F ANY +VVVSDK+ D+ Sbjct: 11 RVLTGTLLLLSS-YSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDK 69 Query: 65 VSATFEQPDPQAFLEQVAVLYNLAWYYDGAVLHVDKSSEVQTRLIHLDKVREPQLRAALQ 124 VS FE +PQ FL+ +A LYNL WYYDG VL++ K+SEV +RLI L + +L+ ALQ Sbjct: 70 VSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQ 129 Query: 125 EGGGWTSRFAWRAAAGGRLVYASGPPRYLDRVEQTVKALEQQASLHDELGGSLSVEVIPL 184 G W RF WR A RLVY SGPPRYL+ VEQT ALEQQ + E G+L++E+ PL Sbjct: 130 RSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPL 189 Query: 185 RHAVAEDREIDYRDQKVAVPGVATILSRVLADANV--VTVDGQSVGEGASVRPGRAVVQA 242 ++A A DR I YRD +VA PGVATIL RVL+DA + VTVD Q + + A+ +A V+A Sbjct: 190 KYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQARVEA 249 Query: 243 EPSLNAIIVRDHAERLPMYRRLVMALDRPAARIEVGLTILDINAEHLSELGVQWQVGIGT 302 +PSLNAIIVRD ER+PMY+RL+ ALD+P+ARIEV L+I+DINA+ L+ELGV W+VGI T Sbjct: 250 DPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRT 309 Query: 303 GKHQLIDIRTSAGQAEGSLAG---SLVDSRGVDRLLAKVTLMQGEGHAQVVSRPTLLTQE 359 G + + I+T+ Q+ + G SLVD+RG+D LLA+V L++ EG AQVVSRPTLLTQE Sbjct: 310 GNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQE 369 Query: 360 NTLAVIDHSETYYVRVMGERVAELKAITYGTLLKMTPRLIRNADRPEISLSLHIEDGNQK 419 N AVIDHSETYYV+V G+ VAELK ITYGT+L+MTPR++ D+ EISL+LHIEDGNQK Sbjct: 370 NAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQK 429 Query: 420 PNSTGPDGIPTISRTVIDTLARVDLGQSLMIGGIHRDESSESIRKVPLLGDIPFLGALFR 479 PNS+G +GIPTISRTV+DT+ARV GQSL+IGGI+RDE S ++ KVPLLGDIP++GALFR Sbjct: 430 PNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFR 489 Query: 480 YHSNNTRRSVRLFLIEPRLIDPGLG 504 S TRR+VRLF+IEPR+ID G+ Sbjct: 490 RKSELTRRTVRLFIIEPRIIDEGIA 514
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 76.9 bits (189), Expect = 3e-18 Identities = 40/167 (23%), Positives = 74/167 (44%), Gaps = 10/167 (5%) Query: 19 LYLGLGQREANEMLAVLDAEGIGAVKAQDKDGKVKILIDEADIGRAVAALKRQGYPREMF 78 L+ L ++ ++A L I + +G I + + L +QG P+ Sbjct: 53 LFSNLSDQDGGAIVAQLTQMNI---PYRFANGSGAIEVPADKVHELRLRLAQQGLPKGG- 108 Query: 79 STVNDVFPRDSLISSPLEEQARLTYVKSQELSRTLSEIDGVLVARVHVVLPEPHDGLRRQ 138 + ++ ++ S EQ EL+RT+ + V ARVH+ +P+P +R Q Sbjct: 109 AVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQ 168 Query: 139 VGAASASIFIKHAADAALDLYTGQ---MKQLLSNSIEGLDYERISVV 182 + SAS+ + ALD GQ + L+S+++ GL +++V Sbjct: 169 K-SPSASVTVTLEPGRALD--EGQISAVVHLVSSAVAGLPPGNVTLV 212
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 32.8 bits (74), Expect = 6e-04 Identities = 49/207 (23%), Positives = 89/207 (42%), Gaps = 24/207 (11%) Query: 12 PMIDPNQTVLRGADYQQYLDTRALTENARQRAREI---DSRADAVLEEHQR---LGREIG 65 P+++P +T++ A+ L A ++ + + R + +Q G E G Sbjct: 24 PIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQGLEQG 83 Query: 66 LEMAAVEQAALLHGTRLRCAEFYRRAD-------RAMSEVVQQAVCKVLGEYPDIVLTLA 118 L A +QA + + +EF D + ++ +A +V+G+ P + + Sbjct: 84 LAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTV--DNS 141 Query: 119 ATRQALAQVSPREPLV-----LHVRPDQLDEVRQRLDEVLVQFPEAGPVELSADARLALG 173 A + + Q+ +EPL L V PD L QR+D++L L D L G Sbjct: 142 ALIKQIQQLLQQEPLFSGKPQLRVHPDDL----QRVDDMLGATLSLHGWRLRGDPTLHPG 197 Query: 174 GCRLEAEDCVIDASIEGQLAALQRALA 200 GC++ A++ +DAS+ + L R A Sbjct: 198 GCKVSADEGDLDASVATRWQELCRLAA 224
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 385 bits (990), Expect = e-136 Identities = 188/345 (54%), Positives = 262/345 (75%) Query: 1 MSAEKTEQPTRAKLRDARRNGQVARSKELVSTVLILSLVALPMGFPDYFLGHLGELMLLP 60 MS EKTEQPT K+RDAR+ GQVA+SKE+VST LI++L A+ MG DY+ H +LML+P Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 61 APLLHLPFHQALEVMLGQLLQELLWLTLPFLLTTVLAGIAGNLLQTGFVFSGQSLAPDLK 120 A +LPF QAL ++ +L E +L P L L IA +++Q GF+ SG+++ PD+K Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 121 KVSLLEGVKRIFSIRNLLDFFKSSLKVMLLGALVLGLLSDHLRTLLRVSSCGIECILPLL 180 K++ +EG KRIFSI++L++F KS LKV+LL L+ ++ +L TLL++ +CGIECI PLL Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 181 GSLIGKLIGVCAVGFLAISAVDYGLERWQHHKQLRMSKEEVKREHKEMEGAPELKRERRK 240 G ++ +L+ +C VGF+ IS DY E +Q+ K+L+MSK+E+KRE+KEMEG+PE+K +RR+ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 241 RHREMQNGTLRADVRRSSVIIANPTHIAIGLRYKPGETPLPLVTLKYTDQQALLVRRLAE 300 H+E+Q+ +R +V+RSSV++ANPTHIAIG+ YK GETPLPLVT KYTD Q VR++AE Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 301 EEGIPVLERIPLARALFADSRVEQYIPGELIQPVAEVIRWLRMQE 345 EEG+P+L+RIPLARAL+ D+ V+ YIP E I+ AEV+RWL Q Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 141 bits (358), Expect = 3e-43 Identities = 53/259 (20%), Positives = 103/259 (39%), Gaps = 8/259 (3%) Query: 4 QTLEQVLLSFSLILPRLFGCFLLLPILGKQVLGGALARNGVACSLALFIYPCVANTLPAE 63 Q L + L F L R+ PIL ++ + + G+A + I P + Sbjct: 8 QWLSWLNLYF-WPLLRVLALISTAPILSERSVPK-RVKLGLAMMITFAIAPSLPANDVPV 65 Query: 64 LDGLQLGLLIGKEVLLGLLLGFVVVIPFWALEACGFLIDNQRGATLASTLNPLLGSQTSP 123 L +++L+G+ LGF + F A+ G +I Q G + A+ ++P Sbjct: 66 FS-FFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPV 124 Query: 124 TGALLVQTLVTLFFTGGAFLGLLGALLGSYASWPVASFYPHVGDQWSTFFLAQFDYLLAL 183 ++ + LF T L L+ L+ ++ + P+ + + Sbjct: 125 LARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLN--SNAFLALTKAGSLIFLN 182 Query: 184 CVLFAAPLLIAMFLAEFGLALVSRFAPSLNVFILSMPIKSLVCSALLV---PYLFLLMTQ 240 ++ A PL+ + L L++R AP L++F++ P+ V +L+ P + Sbjct: 183 GLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEH 242 Query: 241 AEDQVFIALAKVHLLGPLL 259 ++F LA + PL+ Sbjct: 243 LFSEIFNLLADIISELPLI 261
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 65.6 bits (160), Expect = 4e-18 Identities = 30/77 (38%), Positives = 49/77 (63%) Query: 5 EVLHFASQSLWLVLVLSLPTVLMAALVGTLVSLVQALTQVQEQTLGFVAKLVAVIVTLFV 64 +++ +++L+LVL+LS ++A ++G LV L Q +TQ+QEQTL F KL+ V + LF+ Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFL 62 Query: 65 TADWMGSELYRYTDLVL 81 + W G L Y V+ Sbjct: 63 LSGWYGEVLLSYGRQVI 79
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 246 bits (629), Expect = 3e-85 Identities = 93/217 (42%), Positives = 140/217 (64%), Gaps = 7/217 (3%) Query: 6 DELGLILGLALLSLVPFIAVMATSFLKMAVVFSLLRNALGVQQIPPNMALYGLAIILSIY 65 +++ LI LA +L+PFI T F+K ++VF ++RNALG+QQIP NM L G+A++LS++ Sbjct: 3 NDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMF 62 Query: 66 VMAPVGMATYDYLNAHETTLGDARSVERFLEEGMAPFRAFLDRQVNERERAFFLDSARQL 125 VM P+ Y Y + T D S+ + ++EG+ +R +L + + FF ++ + Sbjct: 63 VMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKR 122 Query: 126 WPSQYAERVD-------GNSLLVLLPAFTISELSRAFEIGFLIYLPFIAIDLIISNILLA 178 + E V S+ LLPA+ +SE+ AF+IGF +YLPF+ +DL++S++LLA Sbjct: 123 QYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLA 182 Query: 179 MGMMMVSPVTISLPFKLLLFVLLDGWGRLSHGLVLSY 215 +GMMM+SPVTIS P KL+LFV LDGW LS GL+L Y Sbjct: 183 LGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 82.0 bits (202), Expect = 5e-20 Identities = 41/172 (23%), Positives = 71/172 (41%), Gaps = 14/172 (8%) Query: 139 EHLLTALPRRPLRERLNILLNLSLQWRPLELTLHELRDLGTGDILLLPAGTPSSPQLLGV 198 L RP R + + L L +G GD+LL+ +S + Sbjct: 135 PELPAVGGGRPKMLRWPLRFVIGSSDTQRSL----LGRIGIGDVLLIR----TSRAEVYC 186 Query: 199 LDGQPW----AELQLDDTHLELVRMHDTPPVTDTA--LEALEQLPIPVSFEVGRQTLDLH 252 + E + L++ + + T+TA L L QLP+ + F + R+ + L Sbjct: 187 YAKKLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLA 246 Query: 253 TLSTLQPGALIELHSPLDPQVRILANQRCIGTGVLVQIDGRLGVRVNRLLEQ 304 L + L+ L + + V I+AN +G G LVQ++ LGV ++ L + Sbjct: 247 ELEAMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHEWLSE 298
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 136 bits (343), Expect = 2e-40 Identities = 72/264 (27%), Positives = 131/264 (49%), Gaps = 3/264 (1%) Query: 29 GGGWEATIQARQVTPMGLQAEMAEEVSMAFSSLANARLSARSRVTDARQHGLQAGQAAEE 88 G + + A+MAEEV+ FS L R +++D++ + + Sbjct: 31 LGQFRGESVQIVSGTLQSIADMAEEVTFVFSERKELSLDKR-KLSDSQARVSDVEEQVNQ 89 Query: 89 MLAKVPDVQRRA-LDELVAWLRQHPHLTPGELEARLDGFSGEACQRFLALAYARDALGKV 147 L+KVP+++++ + EL++ L P+++ +L+A L+G S E ++F L RDAL Sbjct: 90 YLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGR 149 Query: 148 ADAGDVPGKLDQAMASMAQTQGQAIELGIEIGPLAQAAQEQGVAEVAALREVYCDFLCGY 207 + + ++QA+ SMA+ QG+ I LG I P A + GV + LR+ Y D + GY Sbjct: 150 PELAHLSHLVEQALVSMAEEQGETIVLGARITPEAYRESQSGVNPLQPLRDTYRDAVMGY 209 Query: 208 RGLRHAWDDLRSRFGDAAISDIAQFMLNGLASHISGPSPHLDSNQLQQVISDMKLVQALK 267 +G+ W DL+ RF + I + F+ L++ + +L VISD++ ++ Sbjct: 210 QGIYAIWSDLQKRFPNGDIDSVILFLQKALSADLQSQQSGSGREKLGIVISDLQKLKEFG 269 Query: 268 KLESDTAALFRQLA-GEPSGVRAF 290 + ++ + G+ +GVR F Sbjct: 270 SVSDQVKGFWQFFSEGKTNGVRPF 293
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 145 bits (367), Expect = 3e-43 Identities = 62/206 (30%), Positives = 122/206 (59%), Gaps = 16/206 (7%) Query: 122 RMDELVMAAMGLRMRKQKTERTELSEQLKCLTAELKIFSMIQSKVNVVMADKGTFMLEDP 181 R+D+ ++ + M R++L E+L LTAELKI+S+IQ+++N ++ GT + D Sbjct: 130 RIDDDILKVIVDSMNHHGDARSKLREELAELTAELKIYSVIQAEINKHLSSSGTINIHDK 189 Query: 182 GFNLFDRTLYDL-DADSWEKSSEYRLLSSLDTFQPAFNGT--AVVTVRHFLAGTQSVTAS 238 NL D+ LY D + ++ S+EY++L + +G+ +V+++ FL Sbjct: 190 SINLMDKNLYGYTDEEIFKASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSEN----- 244 Query: 239 SESSGRLQKVSGPMTDLKAQYAWDKDNNPLANFSQALSDRTRIVNDKVTEQTTLLNDVGS 298 K +G + +LK Y+++KDNN L++F+ SD++R +ND V+++TT L+D+ S Sbjct: 245 --------KRTGALGNLKNSYSYNKDNNELSHFATTCSDKSRPLNDLVSQKTTQLSDITS 296 Query: 299 RYTTSTEVMMKFVETWFSMLSKILQN 324 R+ ++ E + +F++ + S++ ++L + Sbjct: 297 RFNSAIEALNRFIQKYDSVMQRLLDD 322
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 131 bits (330), Expect = 2e-39 Identities = 86/253 (33%), Positives = 131/253 (51%), Gaps = 11/253 (4%) Query: 9 LDGKIAFVSGASRGIGEAIAHLLAQQGAHVIVSSRKLDGCQQVAEAIVAAGGKATAVACH 68 ++GKIAF++GA++GIGEA+A LA QGAH+ + ++V ++ A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 IGEMEQIQQVFAGIREQFGRLDILVNNAAT-NPQFCNVLDTDLGAFQKTVDVNIRGYFFM 127 + + I ++ A I + G +DILVN A P + L + ++ T VN G F Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDE--EWEATFSVNSTGVFNA 123 Query: 128 SVEAGKLMREHGGGSIINVASINGVSPGLFQGIYSVTKAAVINMTKVFAKECAQFGIRCN 187 S K M + GSI+ V S P Y+ +KAA + TK E A++ IRCN Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 188 ALLPGLTDTKFASALVKNDS-----IRNAALQ---QIPLKRVADPSEMAGAVLYLASDAS 239 + PG T+T +L +++ I+ + IPLK++A PS++A AVL+L S + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 240 SYTTGTALNVDGG 252 + T L VDGG Sbjct: 244 GHITMHNLCVDGG 256
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 26.8 bits (59), Expect = 0.005 Identities = 7/22 (31%), Positives = 15/22 (68%) Query: 40 FDRAFMAWIKSAAPATMGDVAD 61 + R ++AW K+A + +G +A+ Sbjct: 20 WRRNYIAWKKAALASLLGHLAE 41
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.009 Identities = 16/88 (18%), Positives = 33/88 (37%), Gaps = 7/88 (7%) Query: 74 SERYRDHVLADRLQAFDSGPSTLALSAVNLTAPEREFEALKAIQAARYVDGLDVTRVETL 133 +++R + A+ L + +G S PE E + Q R V+ R+ L Sbjct: 722 LQKFRGQLFAEALHLYLAG-ERYFPS------PEDEEIYFRPEQELRLVETGVQGRLWAL 774 Query: 134 TAVLANLGLDTAAERLTRPDSALLQVND 161 + AA++ ++ + + D Sbjct: 775 LTREGAPAAEGAAQKGYSVNTTFVTIAD 802
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.5 bits (63), Expect = 0.031 Identities = 24/99 (24%), Positives = 40/99 (40%), Gaps = 13/99 (13%) Query: 1 MKQNILLVAVCAALLQACAPASTSHEGTPSMPATAASPATQPKLSAYYWNLVAANDASGK 60 MK+N+ +V+ AA L A AP + + + A A +A Y V + ++ Sbjct: 1 MKKNLRIVSAAAAALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSISAIA 60 Query: 61 AIAAMA--PGIEGKLRLNFAERNLNINGGCNNQFGGYSY 97 A+A P I G ++ G + + G SY Sbjct: 61 AVAKSDTMPAIPG-----------SLTGSISASYNGKSY 88
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 81.5 bits (201), Expect = 8e-19 Identities = 85/408 (20%), Positives = 162/408 (39%), Gaps = 25/408 (6%) Query: 16 FIDCINLFMPTVALPRITDQFAIGNASSAWVGNAYMLGLTLAVPVSTWLANHWGARRLLC 75 F +N + V+LP I + F AS+ WV A+ML ++ V L++ G +RLL Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL- 82 Query: 76 AAMLGFSVAVWGCGEAA----SFAALIAWRLLQGMAGGLLIPVGQALTFERFQGPE-RAR 130 + G + +G F+ LI R +QG AG P + R+ E R + Sbjct: 83 --LFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVARYIPKENRGK 139 Query: 131 VSTLVMAVALLAPALSPPLGGMIVDHGRWPWVFHCNIPLALLTAALAWAWIDQTPGPTAS 190 L+ ++ + + P +GGMI + W ++ IP+ + + + Sbjct: 140 AFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVRIKG 197 Query: 191 RPDFKGLLLVSATLACLLLGLSLYGAGHGLALTIACLLASVSCALLYRAHYRRSAGGIVE 250 D KG++L+S + +L + Y L+ SV L++ H R+ V+ Sbjct: 198 HFDIKGIILMSVGIVFFMLFTTSYSISF--------LIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 251 LKLLGSPRLRVSMQVYHAIPGVFTGVNLLNIFYLQDVLELSAQATG-LFMLVYATGALAA 309 L + + + I G G + + ++DV +LS G + + + Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 310 MLVAGRLYNRVGAVRLLVLGLLLHSLGISLLIWVATPTDSAALVAAYGLMGIGGGVGAN- 368 + G L +R G + +L +G+ L +S L ++ + ++ + GG+ Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTF--LSVSFLTASFLL-ETTSWFMTIIIVFVLGGLSFTK 366 Query: 369 -TAQTTALLDFSGERMQQASVLWNLNRQMAFSVGAALLLMILNLLLVD 415 T + L N ++ G A++ +L++ L+D Sbjct: 367 TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLD 414
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.6 bits (63), Expect = 0.041 Identities = 15/55 (27%), Positives = 24/55 (43%) Query: 211 TRSGSASVVGKAVYQSNASHAIRAMACAALGVAVLPAWLVEEDLDAGRLQRVLPD 265 T + SA V + V+ NAS A+ A + + WL + G Q+V + Sbjct: 514 TAAQSAGGVAEGVFIKNASEALADFMLARFAMDQIQQWLKQSVEIFGENQKVTAE 568
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.4 bits (159), Expect = 3e-15 Identities = 26/170 (15%), Positives = 65/170 (38%), Gaps = 8/170 (4%) Query: 1 MANHKIEIRRRNVEKILQAAEQVFADKGYGATSMGDIAELAQLPRSNLHYYFSTKDELYR 60 MA + + + IL A ++F+ +G +TS+G+IA+ A + R ++++F K +L+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 AVLQDLLDVWKQ--DALCFERFDDPRVVLTSYIRAK---MGHSRSRPLGSKIW--AEEML 113 + + + + DP VL + R L +I E + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 114 HGAPLLGASLDEILVPWAQLKQAKIRSWVEERRILP-VEPSALLYMIWAA 162 ++ + + + + ++ +E + + + ++ Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY 170
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.6 bits (149), Expect = 5e-14 Identities = 40/204 (19%), Positives = 77/204 (37%), Gaps = 15/204 (7%) Query: 8 APRKRLSREERRRQLLDVAWRLVREEGTDALSLGRLAEQAGVTKPVVYDHFETRNGLLLA 67 A + + +E R+ +LDVA RL ++G + SLG +A+ AGVT+ +Y HF+ ++ L Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 68 LYQEYDARQTAMLDKALAGCPAGLPERAWVIAEAYVDCVATQG-----REIPGVSAALAG 122 +++ ++ + + A P I ++ T+ EI G Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 123 S-PELEALKRGYDGPFMDKCREALLP------FAPGGDIGVAGLWGLMGAADAL--SLAA 173 ++ +R D+ + L A + G L + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA-IIMRGYISGLMENWLF 180 Query: 174 AAEELTAEAAKRELQATIVAMVLR 197 A + + R+ A ++ M L Sbjct: 181 APQSFDLKKEARDYVAILLEMYLL 204
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.8 bits (64), Expect = 0.019 Identities = 8/37 (21%), Positives = 15/37 (40%) Query: 197 IGSALAYLREHYAEPLGVDELASRANMSVSTFHEHFK 233 + AL + + E+A A ++ + HFK Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFK 53
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 100 bits (250), Expect = 1e-26 Identities = 40/141 (28%), Positives = 70/141 (49%), Gaps = 2/141 (1%) Query: 1 MTVSRLLIVDDDVEILALLKQFFVQHGYEVDLAAEGQAMWAAIARQRPDAIILDLMLPGE 60 MT + +L+ DDD I +L Q + GY+V + + +W IA D ++ D+++P E Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 GGLDLCQKLRA-QLGVPVIMLTAMAELSDRIIGLELGADDYLTKPFDPRELLARL-RAVQ 118 DL +++ + +PV++++A I E GA DYL KPFD EL+ + RA+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 119 RRVGEQLPRGEAARPVIGFAG 139 + ++ + G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVG 141
>PF06580#Sensor histidine kinase Length = 349 Score = 31.0 bits (70), Expect = 0.008 Identities = 8/44 (18%), Positives = 16/44 (36%), Gaps = 7/44 (15%) Query: 347 LVENAMKYARDPQ-------ITLRRAAHLIVIEVRDSGPGIPDE 383 LVEN +K+ + + + +EV ++G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN 306
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 50.3 bits (120), Expect = 7e-09 Identities = 34/145 (23%), Positives = 55/145 (37%), Gaps = 13/145 (8%) Query: 302 QIKPQQVAAQTDMPPRYRALAGEAQRLSVNFRFQEGSAGLDNKALRDVQRVGDYLRQAGK 361 Q + V A P + + L + F A L + + ++ L Sbjct: 193 QGEAAPVVAPAPAPAP--EVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDP 250 Query: 362 LQGKVVLVGFGDPKETPGRAALLSRLRAMAVRRELARTGVQVRDVA--GMGDELPVAGND 419 G VV++G+ D + LS RA +V L G+ ++ GMG+ PV GN Sbjct: 251 KDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNT 310 Query: 420 LEQGRLR---------NRRVEVWVY 435 + + R +RRVE+ V Sbjct: 311 CDNVKQRAALIDCLAPDRRVEIEVK 335
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 30.1 bits (68), Expect = 0.006 Identities = 19/94 (20%), Positives = 39/94 (41%), Gaps = 10/94 (10%) Query: 125 VDLH--RHDFKDLQHWMEKQVYLALGTALLGAAAHGLD--ATPIEGFDAKA---LDAELG 177 +DL + + ++ ++ A A HG++ + I D A L+ + Sbjct: 9 LDLQALKQNLSIVRQAATHARVWSVVKA--NAYGHGIERIWSAIGATDGFALLNLEEAIT 66 Query: 178 LREQGFTSVVLLSLGYRSEEDFNAGLSKSRLSAA 211 LRE+G+ +L+ G+ +D + RL+ Sbjct: 67 LRERGWKGPILMLEGFFHAQDLEI-YDQHRLTTC 99
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 63.4 bits (154), Expect = 7e-13 Identities = 62/401 (15%), Positives = 143/401 (35%), Gaps = 20/401 (4%) Query: 31 VALHAINVYIVTTLLPTVIEEIGGL-AFYAWNTTLFVVASIIGSTLSTRLLARGGPRLAY 89 +N ++ LP + + A W T F++ IG+ + +L + G + Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 90 LLALLVFTLGSMLCAQAGSM-PVLLLGRSVQGLGGGILFALSYALIHLVFDSRLWPRAMA 148 L +++ GS++ S +L++ R +QG G AL ++ +A Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 149 LVSAMWGVATLCGPAVGGLFAEGGHWRWAFWSLLPVAGALALIVCLRLPARQALDDNGAR 208 L+ ++ + GPA+GG+ A + W++ L+P+ + + ++L ++ + G Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPMITIITVPFLMKLL-KKEVRIKGHF 199 Query: 209 PAYGLIACLVASVLAICAASLADSLWINLAGIVAGLAIAALIARLDPRARHHLLPTGAYS 268 G+I V V + + ++ ++ + + + + DP + G Sbjct: 200 DIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP-----FVDPGLGK 254 Query: 269 LRQPMGALFAMMCLLVAAITTEIYVPYFLQRIHGFGPLAAG--YLTAVMAAGWTVGALAS 326 M + + VPY ++ +H G + + G + Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 327 AGRDREGGAWQIRSGPLVVAVALLALALLTPAPAWIASAPGLALFALALAGVGLGIGLGW 386 DR G + + G ++V+ L + L +W + + + + Sbjct: 315 ILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTV------ 368 Query: 387 PHLLTRVLQAARPGEENLASASITTVQLYATALAAALAGLV 427 + T V + + E + + + A+ G + Sbjct: 369 --ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.1 bits (65), Expect = 0.003 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 1 MRTT--EDGFTLIEVLVALTIVAVAMAAAVRATGLMTQGNGLLRDKGLA-LLAAQGRLAE 57 MR T + GFTL+E++V + I+ V A++ LM + K ++ ++A + L Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGV--LASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58 Query: 58 LRLEGGAKPGVRQ 70 +L+ P Q Sbjct: 59 YKLDNHHYPTTNQ 71
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 163 bits (413), Expect = 8e-55 Identities = 61/138 (44%), Positives = 85/138 (61%), Gaps = 6/138 (4%) Query: 14 RQQGFTLIEIMVVVVILGILAAMVVPKVLDRPDQARATAARQDIGGLMQALKLYRLDNGA 73 +Q+GFTL+EIMVV+VI+G+LA++VVP ++ ++A A DI L AL +Y+LDN Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHH 65 Query: 74 YPNQNQGLKVLVEKP-AQAKDGQWRA--YLDRLPNDPWGRPYQYLNPGANGEIDVFSLGA 130 YP NQGL+ LVE P + Y+ RLP DPWG Y +NPG +G D+ S G Sbjct: 66 YPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSAGP 125 Query: 131 DGQAGGDGVNADLGSWQL 148 DG+ G + D+ +W L Sbjct: 126 DGEMGTED---DITNWGL 140
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 375 bits (965), Expect = e-122 Identities = 189/669 (28%), Positives = 306/669 (45%), Gaps = 81/669 (12%) Query: 81 VAAPVPANPLGDQPVQLNFVDADIQAVVRGLSRATGRQFLVDPRVKGQLTLVSEGEVPAS 140 + A + P + +F DIQ + +S+ + ++DP V+G +T+ S + Sbjct: 16 IFAALLFRPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEE 75 Query: 141 KAYGMLLSALRMQGFSVVDVG-GVAQVVPQADAKLLAGALVMGDR-DAGNGMVTRTFRLQ 198 + Y LS L + GF+V+++ GV +VV DAK A + G+ +VTR L Sbjct: 76 QYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLT 135 Query: 199 YENAVNLIPVLRPIVSPDNPINA--YPGNNTLVVTDYAENLERVAQILDRVDIPTAIDTD 256 A +L P+LR + + Y +N L++T A ++R+ I++RVD Sbjct: 136 NVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVV 195 Query: 257 VVAINNGIASDIAGMVNEL---LDSQGNDPTQKISVLGDPRSNSVVIRSGSPERTQLARD 313 V ++ A+D+ +V EL + +V+ D R+N+V++ SG P Q Sbjct: 196 TVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLV-SGEPNSRQRIIA 254 Query: 314 LIYKLDNAQNSAGNLHVVYLRNAQADKLAQSLRGLLTGESDTAGNDATRALLSGGGMLTG 373 +I +LD Q + GN V+YL+ A+A L + L G+ M + Sbjct: 255 MIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGI------------------SSTMQSE 296 Query: 374 GSGNGTSGNGGSAQGNSANNNANASRSSNQSAGTTPNGYGSSTQQNDQGLAFSAGGATIQ 433 I+ Sbjct: 297 KQAAKPVAALDK-------------------------------------------NIIIK 313 Query: 434 ADKTTNTLLISAPEPLYRSLREVIDQLDQRRAQVVVESLIVEVGEDDANEFGIQWQAGNL 493 A TN L+++A + L VI QLD RR QV+VE++I EV + D GIQW N Sbjct: 314 AHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNA 373 Query: 494 GKNGVFGGANLGGSGLVKGPSSIDVLPKGLSVGVVDGTVKIPGIG---EVLDLKVLARAL 550 G F + L S + G + + +S + GI + +L AL Sbjct: 374 GMTQ-FTNSGLPISTAIAGANQYNKDGT-VSSSLASALSSFNGIAAGFYQGNWAMLLTAL 431 Query: 551 KSKGGSNVLSTPNLLTLDNEAASIFVGQTIPFVSGQYVTDGGGNSNNPFQTIQREEVGLR 610 S +++L+TP+++TLDN A+ VGQ +P ++G T G N F T++R+ VG++ Sbjct: 432 SSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGD----NIFNTVERKTVGIK 487 Query: 611 LNVRPQISEGGTVKLDVYQEVSSVDQRASSAAGTV---TNKRAIDTSILLDDGQIMVLGG 667 L V+PQI+EG +V L++ QEVSSV ASS + + N R ++ ++L+ G+ +V+GG Sbjct: 488 LKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGG 547 Query: 668 LLQDGYTQTNEGIPWLSGLPGVGALFRSERRASSKTNLMVFLRPYIVRDAAVGRSITLNR 727 LL + T + +P L +P +GALFRS + SK NLM+F+RP ++RD R + + Sbjct: 548 LLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQ 607 Query: 728 YDFIRRAQG 736 Y AQ Sbjct: 608 YTAFNDAQS 616
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 364 bits (936), Expect = e-126 Identities = 178/406 (43%), Positives = 245/406 (60%), Gaps = 6/406 (1%) Query: 1 MNRYRYEAADAQGRVVKGLLEADSPGAAMAQLRALGLTTLEVEVQVVAGQGSG------L 54 M +Y Y+A DAQG+ +G EADS A LR GL L V+ Q SG Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 55 FGAKLSDGDLAWATRQLASLLAAGLPLEAALGATLEQAERKHVAQLLGAVRGDVRSGMRL 114 +LS DLA TRQLA+L+AA +PLE AL A +Q+E+ H++QL+ AVR V G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 115 ADALAERPRDFPEIYRALVAAGEESGDLAQVMERLADYIEDRNTLRGKILTAFIYPGVVG 174 ADA+ P F +Y A+VAAGE SG L V+ RLADY E R +R +I A IYP V+ Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 175 LVSVGIVIFLLSYVVPQVVSAFTQARQDLPGLTLAMLAASDFVREWGGLCFALMAGAFWG 234 +V++ +V LLS VVP+VV F +Q LP T ++ SD VR +G + F Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 235 WRVYLRAPEARLAWHGCVLRLPLFGRFVLGLNTARFASTLAILGSAGVPLLRALEAARQT 294 +RV LR + R+++H +L LPL GR GLNTAR+A TL+IL ++ VPLL+A+ + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 295 LGNDRLDQCVNEATARVREGAGLASALAVEKVFPPLLIHLIASGEKTGNLPPMLDRAADS 354 + ND ++ AT VREG L AL +FPP++ H+IASGE++G L ML+RAAD+ Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 355 LAKDIERRAMGMTALLEPLMIVIMGAVVLLIVMAVLMPIIEINQLV 400 ++ + L EPL++V M AVVL IV+A+L PI+++N L+ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 30.1 bits (67), Expect = 0.038 Identities = 40/160 (25%), Positives = 61/160 (38%), Gaps = 11/160 (6%) Query: 566 AGHNISVPFHPGRVDASQEQTDVESFAVLEPLA--DGFRNFSKARYSVKAEKLLLDKAQL 623 +GH P+ + + DVE PL D FR +K KLL A Sbjct: 164 SGHVRVRPYKEKPIQNQAKSVDVEYTVQFTPLNPDDDFRP------GLKDTKLLKTLAIG 217 Query: 624 LTLTAPELTVLIGGLRVLGANHGGSKDGVFTDRVGVLSNDFFRNLLDMGVEWKPTSADNE 683 T+T+ EL L +L NH G + ND FR +L M E+ + E Sbjct: 218 DTITSQEL--LAQAQSILNKNHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYRVKNRE 275 Query: 684 AFEGRDRKTGQVKWTASRVDLVFGSHAQLRALSEVYGSSD 723 ++K+G + + DL+ + L+ + Y D Sbjct: 276 QAYRINKKSG-LNEEINNTDLISEKYYVLKKGEKPYDPFD 314
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 63/315 (20%), Positives = 113/315 (35%), Gaps = 46/315 (14%) Query: 52 VALLKTFAVFAVAFALRPLGGIVFGALGDRLGRKRILSLTILLMAGSTTLIGLLPTYASI 111 LL +A+ A A P+ G AL DR GR+ +L +++ A ++ P Sbjct: 46 GILLALYALMQFACA--PVLG----ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW-- 97 Query: 112 GVLAPVLLTLARCLQGFSAGGEYAGACAYLMEHAPRGKRAFYGSFVPVSTFSAFACAAVI 171 +L + R + G + G A A AY+ + +RA + F+ V+ Sbjct: 98 ------VLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 172 AYGLEASLTPEAMNAWGWRVPFLVAAPLGLVGLYLR--WRMEETPAFRQALAEGKAHAHS 229 GL +P PF AA L + E R+ L + + Sbjct: 151 G-GLMGGFSP--------HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLA 201 Query: 230 PLGDTLRHHGRTIRNLGAFISLTALSFYM------FTTYFATYLQTVGHLSRAQ-ALLVS 282 R R + +L A+ F M + + + H + ++ Sbjct: 202 SF--------RWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLA 253 Query: 283 TVALLFAAAGCPLAGAFSDRVGRRRTIGF-----TCLWVMLAVFPAYWLASSGSLSGALL 337 +L + A + G + R+G RR + +++LA W+A + A Sbjct: 254 AFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG 313 Query: 338 GVILLAIGALMSGVV 352 G+ + A+ A++S V Sbjct: 314 GIGMPALQAMLSRQV 328
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.1 bits (62), Expect = 0.038 Identities = 10/22 (45%), Positives = 13/22 (59%) Query: 40 LGVVGPNGSGKSTLLKLLAGLR 61 + + G G GKSTL+ L GL Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD 620
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 32.6 bits (74), Expect = 0.002 Identities = 52/278 (18%), Positives = 88/278 (31%), Gaps = 47/278 (16%) Query: 35 PQTFAQAPQRAVTIGQAGTELLYALGLG----ERLAGTSLWFNN-VLPEFKAQNDKVERL 89 A P R V + ELL ALG+ LW + LP+ ++ Sbjct: 28 AHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPD-----SVIDVG 82 Query: 90 ADNEPGFEAVVGKRPQLVTAQFEWMVGPQGAVGTREQFAELGIPTYLLPSDCEGKDNLVG 149 EP E + +P MV G + E A + P +GK L Sbjct: 83 LRTEPNLELLTEMKPSF-------MVWSAGYGPSPEMLARI-APGRGFNFS-DGKQPL-- 131 Query: 150 ADGTRLQPFRIDTIYKSVSQLAEIFDVQDRGERLNAELKGQLDQARQRLAGQDLSHTSAL 209 KS++++A++ ++Q E A+ + + + R + L Sbjct: 132 -----------AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPL-LL 179 Query: 210 FWFSSADLKVDPYVAGRQGVADFMLQTLGVRNVVE-SSEEW--PAVGWETLARANPTWLI 266 V G + +L G+ N + + W AV + LA ++ Sbjct: 180 TTLIDPR---HMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVL 236 Query: 267 VARMDRRRYPADDYRKKLEFLRSDPVTRNMDAVRQGRI 304 + L + P+ + M VR GR Sbjct: 237 CF-----DHDNSKDMDALM---ATPLWQAMPFVRAGRF 266
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 3e-23 Identities = 64/239 (26%), Positives = 107/239 (44%), Gaps = 19/239 (7%) Query: 7 VVILTGASGGIGLELAEQLCAAGAQVLAVSRHMGKLAGLMNRYPDRLRWQEA---DLRSQ 63 + +TGA+ GIG +A L + GA + AV + KL +++ R EA D+R Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 64 AGREQVVSR-AREMGTVNVLINAAGVNRFALLDQLDEHALDELLDINLKAPLQLTRACLP 122 A +++ +R REMG +++L+N AGV R L+ L + + +N +R+ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 123 LLRAQPKALVVNVGSTYGSIGYPGYATYCASKFALRGFSEALRRELADTTVNVLYAAPRA 182 + + +V VGS + A Y +SK A F++ L ELA+ + +P + Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 183 TRTGMNSSAATALNQALKV---------------GMDDPADVARAVLAAVQSERSELYL 226 T T M S N A +V + P+D+A AVL V + + + Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 3e-25 Identities = 39/145 (26%), Positives = 68/145 (46%), Gaps = 5/145 (3%) Query: 2 RLLLVEDDIALGEGICDGLRQEGYTLDWLRDGVSALHALQHEAFDLVILDLGLPRMDGLE 61 +L+ +DD A+ + L + GY + + + + DLV+ D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLRRVRAGGDSLPVLILTARDALDDRITGLDAGADDYLVKPFDLNE-LKARLRALLRRSA 120 LL R++ LPVL+++A++ I + GA DYL KPFDL E + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GRAKVVVE----HAGVSLDPATQQV 141 +K+ + V A Q++ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEI 149
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 1e-06 Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 21/105 (20%) Query: 355 IALQNLVSNAVEH----SPPAGRITVSLRRLDGALELVVEDEGPGIDEASLSRVFERFYS 410 + +Q LV N ++H P G+I + + +G + L VE+ G + Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------------ 305 Query: 411 RNSPNGAGLGLSIVATIIDRLGG---QVRLENRAGGGLAATLLLP 452 N+ G GL V + L G Q++L + G A +L+P Sbjct: 306 -NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (280), Expect = 1e-31 Identities = 76/253 (30%), Positives = 117/253 (46%), Gaps = 13/253 (5%) Query: 40 LEGKIALITGADSGIGRAVAIAYAREGADVAIAYLNEHEDAQETARWVEAAGRQCLLLPG 99 +EGKIA ITGA GIG AVA A +GA +A N E ++ ++A R P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPA 64 Query: 100 DLAQKQHCYDIVEKTVRQFGRIDILVNNAAFQMSHETLEEIDDDEWVKTFDTNITAIFRI 159 D+ +I + R+ G IDILVN A + + + D+EW TF N T +F Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 160 CQAALPSMP--KGSSIINTSSVNSDDPSPSLLAYATTKGAIANFTAGLAQLLGKKGIRVN 217 ++ M + SI+ S + P S+ AYA++K A FT L L + IR N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 218 SVAPGPI-----WTPLIPATMPDEAVKNFGSSY----PMGRPGQPVEVAPIYVLLGSDEA 268 V+PG W+ ++ +K ++ P+ + +P ++A + L S +A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 269 SYISGSRYAVTGG 281 +I+ V GG Sbjct: 244 GHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 3e-16 Identities = 21/144 (14%), Positives = 48/144 (33%), Gaps = 1/144 (0%) Query: 1 MEILTEQGFAATGIEAVLKRVQVPKGSFYHYFDSKEAFGQAVLQRYADYFAQKLERNFGD 60 + + ++QG ++T + + K V +G+ Y +F K + + + Sbjct: 21 LRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAK 80 Query: 61 LSVSPLRRLSNFVEEAKAGMARYQFRRGCLVGNLGQEVLVLPDSFREQLELTL-QDWEQR 119 PL L + + RR + + V + +Q + L + R Sbjct: 81 FPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDR 140 Query: 120 LAACLEEAVNLGEVPCGHDCKALA 143 + L+ + +P + A Sbjct: 141 IEQTLKHCIEAKMLPADLMTRRAA 164
>PF05043#Transcriptional activator Length = 493 Score = 28.4 bits (63), Expect = 0.036 Identities = 17/65 (26%), Positives = 35/65 (53%), Gaps = 6/65 (9%) Query: 1 MNRNDLRRVDLNLLIVFETLMHERSVTRA--AEKLFLGQPAISAALSRLRNLFDDPLFVR 58 +++ R+++L L ++FE H+R R+ AE L + A+ LS +++ F D +F Sbjct: 5 LSKKSHRQLEL-LELLFE---HKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHS 60 Query: 59 TGRSM 63 + + Sbjct: 61 STNGI 65
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.6 bits (66), Expect = 0.011 Identities = 17/82 (20%), Positives = 40/82 (48%), Gaps = 4/82 (4%) Query: 92 LTSDLQAVPGQSERLPQLDAQVAELSGQLKTIDDSWKNRVQGMQETLDSRKALIDELESR 151 T+D + L+A+ A+L Q + ++ + Q ++ LD+ + +LE+ Sbjct: 276 STADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN----RQSLRRDLDASREAKKQLEAE 331 Query: 152 NKALNEQLEQSQSTLRDTQARL 173 ++ L EQ + S+++ + + L Sbjct: 332 HQKLEEQNKISEASRQSLRRDL 353
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 96.4 bits (240), Expect = 4e-24 Identities = 83/334 (24%), Positives = 128/334 (38%), Gaps = 31/334 (9%) Query: 54 GAAVTVAGVVWVLLARPWGRLADRYGRRRVLLLGSGGFTLAYWVLCLFIDGALRWLPGAS 113 G + + ++ A G L+DR+GRR VLL+ G + Y ++ + Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIM------------ATA 93 Query: 114 VAFFGLMLARGLIGAFYAALPVGGNALIADHVEPQRRARAMASLGAANAVGLVVGPALAA 173 + L + R + G A V G A IAD + RAR + A G+V GP L Sbjct: 94 PFLWVLYIGRIVAGITGATGAVAG-AYIADITDGDERARHFGFMSACFGFGMVAGPVLGG 152 Query: 174 LLSRYSLSLPFYAMSLLPATAFVVLLFKLKP------QPLAQSHAPNPVRLSDPRLRRP- 226 L+ +S PF+A + L F+ F L +PL + R Sbjct: 153 LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 227 ---LLVAFSAMLSITVSQIAVGFFALDRLRLEAGDAAQAAGIALTCVGVALMLAQVFLRR 283 + V F L V F DR +A GI+L G+ LAQ + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT----IGISLAAFGILHSLAQAMITG 268 Query: 284 L---EWPPAKMIRIGASISGLGFAAAALATQAPWLWGAFFVAAFGMGFVFPAFSALAANA 340 + + +G G G+ A AT+ + + A G G PA A+ + Sbjct: 269 PVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQ 327 Query: 341 MQAGEQGATAGSIGAAQGMGAVIGPLAGTLVYAL 374 + QG GS+ A + +++GPL T +YA Sbjct: 328 VDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361 Score = 36.0 bits (83), Expect = 2e-04 Identities = 36/136 (26%), Positives = 51/136 (37%), Gaps = 3/136 (2%) Query: 256 AGDAAQAAGIALTCVGVALMLAQVFLRRLEWPPAKMIRIGASISGLGFAAAALATQAPWL 315 + D GI L + L L + + S++G A +AT AP+L Sbjct: 38 SNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMAT-APFL 96 Query: 316 WGAFF--VAAFGMGFVFPAFSALAANAMQAGEQGATAGSIGAAQGMGAVIGPLAGTLVYA 373 W + + A G A A+ E+ G + A G G V GP+ G L+ Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG 156 Query: 374 LDPRLPFLAVGALLLL 389 P PF A AL L Sbjct: 157 FSPHAPFFAAAALNGL 172
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.1 bits (70), Expect = 0.002 Identities = 10/30 (33%), Positives = 18/30 (60%), Gaps = 4/30 (13%) Query: 103 LAVSPDHRRQGIARGLLSA----ARERYAC 128 +AV+ D+R++G+ LL A+E + C Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFC 124
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1058 bits (2738), Expect = 0.0 Identities = 407/567 (71%), Positives = 471/567 (83%), Gaps = 2/567 (0%) Query: 3 RISRRAYADMFGPTVGDRVRLADTALWVEVEKDFTIYGEEVKFGGGKVIRDGMGQGQML- 61 R+SR AYA+MFGPTVGD+VRLADT L++EVEKDFT +GEEVKFGGGKVIRDGMGQ Q+ Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 62 AAEAMDLVLTNALIIDHWGIVKADIGVKHGRIAAIGKAGNPDVQPGVTVPVGPGTEVIAA 121 A+D V+TNALI+DHWGIVKADIG+K GRIAAIGKAGNPD+QPGVT+ VGPGTEVIA Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAG 123 Query: 122 EGKIVTAGGIDSHIHFICPQQVDEALTSGVTTFIGGGTGPATGTNATTCTPGPWYLARML 181 EGKIVTAGG+DSHIHFICPQQ++EAL SG+T +GGGTGPA GT ATTCTPGPW++ARM+ Sbjct: 124 EGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMI 183 Query: 182 QAADCLPINIGLLGKGNASRPEALREQIAAGAVGLKLHEDWGSTPAAIDCCLGVAEEMDI 241 +AAD P+N+ GKGNAS P AL E + GA LKLHEDWG+TPAAIDCCL VA+E D+ Sbjct: 184 EAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDV 243 Query: 242 QVAIHTDTLNESGCIEDTLAAIGERTIHTFHTEGAGGGHAPDIIRAAGQANVLPSSTNPT 301 QV IHTDTLNESG +EDT+AAI RTIH +HTEGAGGGHAPDIIR GQ NV+PSSTNPT Sbjct: 244 QVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPT 303 Query: 302 LPYTVNTVDEHLDMLMVCHHLDPSIAEDVAFAESRIRRETIAAEDILHDMGAFAMTSSDS 361 PYTVNT+ EHLDMLMVCHHL P+I ED+AFAESRIR+ETIAAEDILHD+GAF++ SSDS Sbjct: 304 RPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDS 363 Query: 362 QAMGRVGEVVLRTWQVAHQMKLRRGPLAPDGAYSDNFRVKRYIAKYTLNPALTHGIAHEV 421 QAMGRVGEV +RTWQ A +MK +RG L + +DNFRVKRYIAKYT+NPA+ HG++HE+ Sbjct: 364 QAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEI 423 Query: 422 GSVEVGKLADLVLWAPAFFAVKPALVLKGGMIATAPMGDINGSIPTPQPVHYRPMFGALG 481 GS+EVGK ADLVLW PAFF VKP +VL GG IA APMGD N SIPTPQPVHYRPMFGA G Sbjct: 424 GSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYG 483 Query: 482 AARHATRMTFLPQAALDRGLPHELKLQSLIGVAHGCR-RVRKADMVHNTLQPLIEVDAQT 540 +R + +TF+ QA+LD GL L + + R + KA M+HN+L P IEVD +T Sbjct: 484 RSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPET 543 Query: 541 YQVRADGELLVCEPAHELPLAQRYFLF 567 Y+VRADGELL CEPA LP+AQRYFLF Sbjct: 544 YEVRADGELLTCEPATVLPMAQRYFLF 570
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.0 bits (65), Expect = 0.043 Identities = 4/29 (13%), Positives = 9/29 (31%) Query: 180 SWLCGIALVLVLGLWWLRRQHPLTLRWDH 208 W+ L + + RQ + + Sbjct: 228 PWMLLALLAGFMAFRVMLRQEKRRVSFHR 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 61/311 (19%), Positives = 114/311 (36%), Gaps = 24/311 (7%) Query: 13 LLGLFIIALGNG-VLSSLTTL--RLGAAGESATTIGVVSSAYFIGLTLGAIFNNRLILRI 69 L + + A+G G ++ L L L + + G++ + Y + A L R Sbjct: 11 LSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF 70 Query: 70 GHIRAYSSFAALIGATILLQGLFYDTTWW--FALRLINGWAAVGVFLVIESWLLLAGDAK 127 G R +L GA + + W + R++ G V +++ D Sbjct: 71 G--RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITG-ATGAVAGAYIADITDGD 127 Query: 128 IRGRLLALYMIAFYGAGVIAQAGLGEVTG-WGETAPFMVAGMLATLS-VLPIVILP---- 181 R R +M A +G G++A LG + G + APF A L L+ + +LP Sbjct: 128 ERARHFG-FMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186 Query: 182 -RVSPLLDQVEPLKPRQLLGVAPTGLVGCFGSGVAIAGI----YALLPLYLQ-RIGLDVG 235 PL + T + + + AL ++ + R D Sbjct: 187 GERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDAT 246 Query: 236 KVGDMMAWV-ILGAMLLQYPVGRWSDR-KDRQDVLIALAALCTVLSVLIVLLPADTVLLP 293 +G +A IL ++ G + R +R+ +++ + A T +L+ + P Sbjct: 247 TIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY-ILLAFATRGWMAFP 305 Query: 294 ALLFLLGGGVF 304 ++ L GG+ Sbjct: 306 IMVLLASGGIG 316 Score = 29.4 bits (66), Expect = 0.028 Identities = 40/182 (21%), Positives = 62/182 (34%), Gaps = 8/182 (4%) Query: 204 TGLVGCFGSGVAIAGIYALLPLYLQRIGLD---VGKVGDMMAWVILGAMLLQYPVGRWSD 260 L V I I +LP L+ + G ++A L +G SD Sbjct: 9 VILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 261 RKDRQDVLIALAALCTVLSVLIVLLPADTVLLPALLFLLGGGVFALYPVAVSSAADRAPA 320 R R+ VL+ A V ++ P VL + ++ G A VA + AD Sbjct: 69 RFGRRPVLLVSLAGAAVDYAIMATAPFLWVLY--IGRIVAGITGATGAVAGAYIADITDG 126 Query: 321 DALVPMIQGLLLINSLGSAMAPLAISPMMTAYGEAGLFWAFAAINL--AMVGFFLWRRGK 378 D + G P + +M + F+A AA+N + G FL Sbjct: 127 DERARHFGFMSACFGFGMVAGP-VLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESH 185 Query: 379 RP 380 + Sbjct: 186 KG 187
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 1e-04 Identities = 17/138 (12%), Positives = 43/138 (31%), Gaps = 16/138 (11%) Query: 20 SLAASASAETLEERLRTQLRTT-TQQLQALQSEQAQASAARQAAEQQRDAAQGQVRELTA 78 L + + E +L + +Q Q+++ Q +R ++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYEN 228 Query: 79 QLAKARGQSEQLAGQQQAVHSQAQALVASSNEQLHKYKQAYDELLAMARAKESERATLQA 138 + +L +H Q A + + + + Y E +E ++ Sbjct: 229 LSRVEK---SRLDDFSSLLHKQ-----AIAKHAVLEQENKYVEA-------VNELRVYKS 273 Query: 139 QLGERDGQVQQCQARNQQ 156 QL + + ++ + Q Sbjct: 274 QLEQIESEILSAKEEYQL 291 Score = 29.4 bits (66), Expect = 0.011 Identities = 19/127 (14%), Positives = 39/127 (30%), Gaps = 14/127 (11%) Query: 5 AYRHRCAWLMLALGASLAASASAETLEERLRTQLRTTTQQLQALQSEQAQASAARQA--- 61 ++++ L L A + R R +L S + + A+ A Sbjct: 197 TWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLE 256 Query: 62 AEQQRDAAQGQVRELTAQLAKARGQSEQLAGQQQAVHS-----------QAQALVASSNE 110 E + A ++R +QL + + + Q V Q + Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 111 QLHKYKQ 117 +L K ++ Sbjct: 317 ELAKNEE 323
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.5 bits (63), Expect = 0.001 Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 17 PEPEPEPEPEPEPEPEPEPRPKKKRTAAPGEHQHRGPR 54 P P+P P+P P+P P+P P+ + P + R P Sbjct: 569 PAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPE 606 Score = 27.0 bits (59), Expect = 0.004 Identities = 14/42 (33%), Positives = 23/42 (54%), Gaps = 1/42 (2%) Query: 17 PEPEPEPEPEPEPEP-EPEPRPKKKRTAAPGEHQHRGPRGKP 57 P+P P+P P+P P+P +P P+ + P + Q P +P Sbjct: 571 PKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP 612
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 310 bits (795), Expect = e-101 Identities = 133/369 (36%), Positives = 190/369 (51%), Gaps = 52/369 (14%) Query: 307 RALQLPRHGRFSGPTPTTRSTEPAKIQALEALAGGDARLARALRMARQGLANGLPVLLLG 366 RAL P+ S Q L G A + R+ + + L +++ G Sbjct: 117 RALAEPKR---------RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 367 ETGTGKEVAARALHQAGMRADKPFVAVNCAAIPEGLIESELFGYREGAFTGSRRGGMVGR 426 E+GTGKE+ ARALH G R + PFVA+N AAIP LIESELFG+ +GAFTG++ GR Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRST-GR 226 Query: 427 LMQAHGGTLFLDEIGDMPLALQARLLRVLQERRVAPLGAGDEQDIDVALICATHRDLKRL 486 QA GGTLFLDEIGDMP+ Q RLLRVLQ+ +G DV ++ AT++DLK+ Sbjct: 227 FEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQS 286 Query: 487 VADQQFREDLYYRVNGVSLRLPALRER-DDLATLIQGLLDKS---GARGVSLDAPLVALL 542 + FREDLYYR+N V LRLP LR+R +D+ L++ + ++ G D + L+ Sbjct: 287 INQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELM 346 Query: 543 ENFDWPGNIRQLEMVVRTALAMREEGEQVLTLDHLTDCLLDELASGAAPSG--------- 593 + WPGN+R+LE +VR A+ + V+T + + + L E+ Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQD--VITREIIENELRSEIPDSPIEKAAARSGSLSI 404 Query: 594 ---------------------------SLRDNELELVRAALARHQGNVSAAAEALGISRA 626 L + E L+ AAL +GN AA+ LG++R Sbjct: 405 SQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRN 464 Query: 627 TLYRKLKQL 635 TL +K+++L Sbjct: 465 TLRKKIREL 473
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 60.2 bits (146), Expect = 6e-13 Identities = 40/157 (25%), Positives = 70/157 (44%), Gaps = 19/157 (12%) Query: 7 IGVIDSGCSPEQA--AGLLDARRFWLEEGRLREGDSLPDALGHGSAV---LARLRAESGA 61 + V+D+GC + + R + + + + D GHG+ V +A E+G Sbjct: 45 VAVLDTGCDADHPDLKARIIGGRNF-TDDDEGDPEIFKDYNGHGTHVAGTIAATENENGV 103 Query: 62 QPV------LLAQVFAGQGSTSALQVAAGLLWLVEAGASVVNLSLGLRQDRPVLRQACAE 115 V L+ +V QGS + G+ + +E ++++SLG +D P L +A + Sbjct: 104 VGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDVPELHEAVKK 163 Query: 116 AVAAGVLLCASSPARG-------EPVYPASYPGVIRV 145 AVA+ +L+ ++ G E YP Y VI V Sbjct: 164 AVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISV 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.009 Identities = 20/141 (14%), Positives = 38/141 (26%), Gaps = 19/141 (13%) Query: 211 EPRLFERLQRHGWD---------VERLALGSPAQSLE----QLRRGYRRVRDLLAYGREV 257 + E ++ H W V RL P + + + Sbjct: 339 DQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAAR 398 Query: 258 LPDEHLLSLARYRLPALLWRHRNDDALDELLEPLQRIRAKDASGQLLLTLRAWCAHDGQS 317 + + + L + + L L A A G Sbjct: 399 SGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYP------LILAALTATRGNQ 452 Query: 318 QACAEALGIHRNSLRYRLERI 338 A+ LG++RN+LR ++ + Sbjct: 453 IKAADLLGLNRNTLRKKIREL 473
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.8 bits (85), Expect = 2e-05 Identities = 14/41 (34%), Positives = 27/41 (65%), Gaps = 1/41 (2%) Query: 1 MNRQAGFTLVEVMIAILLMAVV-SLVAWRGLDSVSRADRHV 40 ++Q GFTL+E+M+ I+++ V+ SLV + + +AD+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQK 44
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 54.2 bits (130), Expect = 4e-12 Identities = 27/122 (22%), Positives = 44/122 (36%), Gaps = 2/122 (1%) Query: 4 QRGFTLIELMVVLVIVGIASATISLNIRPDPGKHLRADAERLARLLELAQSEVQADGQPL 63 QRGFTL+E+M++L+++G+++ + L R L Q GQ Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFF 62 Query: 64 RWHSDRGGYRFIRADGQVLADGPLKPRSWQAEAVKVQSEPRGAVWLDGEWIGTPLTLRLR 123 ++F+ + + AD W + G V G G L L Sbjct: 63 GVSVHPDRWQFLVLEARDGADPAPADDGWSGY--RWLPLRAGRVATSGSIAGGKLNLAFA 120 Query: 124 SG 125 G Sbjct: 121 QG 122
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 145 bits (367), Expect = 1e-44 Identities = 79/263 (30%), Positives = 122/263 (46%), Gaps = 19/263 (7%) Query: 1 MNARYDFQGRTVLVTGAAGGIGQAIVEGFARGGARVLAVDLDPQALQRLVEDQLALGHQV 60 MNA+ +G+ +TGAA GIG+A+ A GA + AVD +P+ L+++V A Sbjct: 1 MNAK-GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA 59 Query: 61 RGEMLDLADPGAIRA----LLAGLERLDVLVHNAAYFPLTPFPEIDPALLQRTLAVNLEA 116 D+ D AI + + +D+LV+ A + + T +VN Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 117 LFWLTQGALPLFRRQGGGCV--LATSSVTGPRVAYPGLSHYAASKAGVNGFIRNAALELA 174 +F ++ + G + + ++ PR ++ YA+SKA F + LELA Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRT---SMAAYASSKAAAVMFTKCLGLELA 176 Query: 175 PFNVRVNGVEPGMVRTPAMDNL--GDTALNTRIAA-------GVPLGRLGEPADIAAAML 225 +N+R N V PG T +L + I G+PL +L +P+DIA A+L Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 226 FLSCDAARYITGQTLVVDGGATL 248 FL A +IT L VDGGATL Sbjct: 237 FLVSGQAGHITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.4 bits (247), Expect = 4e-27 Identities = 68/249 (27%), Positives = 107/249 (42%), Gaps = 7/249 (2%) Query: 2 LITGAGSGIGEACALRLARQGWRVALVGRRREALERVAQRCDGLV-----LAGDAADSTS 56 ITGA GIGEA A LA QG +A V E LE+V D DS + Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAA 71 Query: 57 WAGFIEQVRARFGGLDAVIACAGGHGLGRAEQTSDDAWREALRSNLDSAFHTARACLPLL 116 ++ G +D ++ AG G SD+ W N F+ +R+ + Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYM 131 Query: 117 RERR-GSLVLLGSIASLAAGPEVCGYTTAKHALVGLTRSLARDYGPFGVRVNCVCPGWVR 175 +RR GS+V +GS + + Y ++K A V T+ L + + +R N V PG Sbjct: 132 MDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTE 191 Query: 176 TPMADQEMQPLMDHYQEDLDAAYRRVTADVPLRRPAGSDEIAAVCQFLVGVEASIVTGAV 235 T M + + ++ + + +PL++ A +IA FLV +A +T Sbjct: 192 TDM-QWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHN 250 Query: 236 ITADGGSTV 244 + DGG+T+ Sbjct: 251 LCVDGGATL 259
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.5 bits (68), Expect = 0.008 Identities = 23/121 (19%), Positives = 39/121 (32%), Gaps = 11/121 (9%) Query: 77 GIYLVD---FIKHEAGQAWSVSLVLDTLEHAFTAVLGRLPDQAR-TQRGLYA--LALAGE 130 GIY+ + F +E S+ + + H FT L Q R G++ Sbjct: 473 GIYIENIGTFFTYERTPEESIYTLEELFRHEFTHYL-----QGRYVVPGMWGQGEFYQEG 527 Query: 131 ALTGVEASFLHGSLDRPWQAGACPHAPTTELVGLRNHYRYSPTEEYEHIYLNANYYSWQC 190 LT E G P T+ + + R S Y + ++Y++ Sbjct: 528 VLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYGSWDFYNYGF 587 Query: 191 L 191 Sbjct: 588 A 588
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 32.0 bits (72), Expect = 0.005 Identities = 25/100 (25%), Positives = 40/100 (40%), Gaps = 4/100 (4%) Query: 1 MSDIALLPSVSAFLARDHGLYIHGTSVASQSTARITVHNPANSEAIAQVADAN-LADVER 59 ++ AL P +SA A G ++GT A A + N A A + A L V Sbjct: 231 VAAGALNPFISAGEALGIGDILYGTRYAIDKAA---MRNIAPLPAEGKFAVIGGLGSVAG 287 Query: 60 AVESSRQGFANWSRTSPAARAAVLFRLADLLEANREELAQ 99 +++R+ W + +P A V A +LA+ Sbjct: 288 FEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKVAKLAK 327
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.015 Identities = 9/21 (42%), Positives = 12/21 (57%) Query: 47 LVGESGCGKSTLARAILQLTP 67 + GESG GK +ARA+ Sbjct: 165 ITGESGTGKELVARALHDYGK 185
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.0 bits (65), Expect = 0.027 Identities = 21/72 (29%), Positives = 28/72 (38%), Gaps = 17/72 (23%) Query: 66 VEGQAVRLAGHDLLRLDEAGMRRLRGRELGMIFQNPSSHLDPLMRIGEQIAEGIRLHQGS 125 V +VR+ G DEA + +R R G + IGE AE I+ GS Sbjct: 182 VYSSSVRIGGDRF---DEAIINYVR-RNYGSL-------------IGEATAERIKHEIGS 224 Query: 126 SRREARAEAIEV 137 + IEV Sbjct: 225 AYPGDEVREIEV 236
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 50.4 bits (120), Expect = 1e-09 Identities = 49/246 (19%), Positives = 92/246 (37%), Gaps = 38/246 (15%) Query: 12 NVLVCGASQGIGLALCSQLLARDDVGLLLAVSRQATSSPELDVLAQTHGRRLLRLDCDAR 71 + GA+QGIG A+ L ++ + AV ++ + R D R Sbjct: 10 IAFITGAAQGIGEAVARTLASQG--AHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 72 DEQALQVLADQIRGCCDQLNLVISTLGVLQAPPARAEKSLAQLDLAGLQASFATNCFAPV 131 D A+ + +I ++++++ GVL+ + L +A+F+ N Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGL------IHSLSDEEWEATFSVNSTGVF 121 Query: 132 LLLKHLLPLLRRQP----VTFAALSARVGSIGDNHLGGWYSYRASKAALNQLLRTASIEL 187 + + + + VT + A V +Y +SKAA + +EL Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMA------AYASSKAAAVMFTKCLGLEL 175 Query: 188 KRLNPASTVLALHPGTTDTLLSRP------------------FQGNVPLEKLFAPAFAAS 229 N +++ PG+T+T + F+ +PL+KL P+ A Sbjct: 176 AEYNIRCNIVS--PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIAD 233 Query: 230 CILELV 235 +L LV Sbjct: 234 AVLFLV 239
>PF05043#Transcriptional activator Length = 493 Score = 36.8 bits (85), Expect = 2e-04 Identities = 11/40 (27%), Positives = 19/40 (47%) Query: 47 FLKEGASLEEIQEKYGMPRSTLYRVIDKCEALDKSGSPIG 86 F EG E I +++ + S+LYR+I + + K Sbjct: 96 FFNEGCQAESICKEFYISSSSLYRIISQINKVIKRQFQFE 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 339 bits (870), Expect = e-112 Identities = 138/412 (33%), Positives = 200/412 (48%), Gaps = 26/412 (6%) Query: 257 LDLEQAFAEGGEENRVIRLGSHAVVSNLLPILENGQRTGLVLTC--QDTTAVQRADQRIR 314 DL + + V+ + + + E G L + + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 315 STRRPGAFTARYRLEQLDGNSRANREMLQLARRFAASQSTILITGESGTGKELLAQGIHN 374 R L G S A +E+ ++ R + T++ITGESGTGKEL+A+ +H+ Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 375 ESPRRQGPFVAINCAAFPESLLESELFGYEEGAFSGSRKGGKPGLFEVAHRGTLFLDEIG 434 RR GPFVAIN AA P L+ESELFG+E+GAF+G+ + G FE A GTLFLDEIG Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGA-QTRSTGRFEQAEGGTLFLDEIG 241 Query: 435 DMPVSLQTRLLRVLQEREVLRLGGTEPIAIDVRIIAATHQDLSAAIQDGDFRTDLYYRLN 494 DMP+ QTRLLRVLQ+ E +GG PI DVRI+AAT++DL +I G FR DLYYRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 495 ILRLQTTPLRERPEDIALICRGISQRLLVQGQPPGAAEVPGALLPYLARYGWPGNVRELE 554 ++ L+ PLR+R EDI + R Q+ +G L + + WPGNVRELE Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDV--KRFDQEALELMKAHPWPGNVRELE 359 Query: 555 NVIERAM-LSARELLGEHGVDEQYLARVLPELCQSVAPTSR------------------- 594 N++ R L ++++ ++ + + + + A S Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 595 -ARPSRESDLHSIGKAAQLRHVQETLDNCQGNLDDAARQLGISRTTLWRRLR 645 + + + L +GN AA LG++R TL +++R Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.5 bits (110), Expect = 1e-08 Identities = 28/202 (13%), Positives = 66/202 (32%), Gaps = 22/202 (10%) Query: 6 AEERRQDFIEATVKVIAEHGVANATTRRIAAAADSPLASLHYVFHTKDELFYAV----YE 61 A+E RQ ++ +++ ++ GV++ + IA AA ++++ F K +LF + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 62 SLINLPQQSLQHVPAGATAAESVGEMLRQLVNWFTAHPEMATTQFELFCWNLRNNPEMAA 121 ++ L + P + E+L ++ + + Sbjct: 69 NIGELELEYQAKFP--GDPLSVLREILIHVLESTVTEERRRLL---MEIIFHKCEFVGEM 123 Query: 122 KIYAVSIDATQQA----IAKVTGSALDQAAVA------TVSRLLINLFDGLMLAWSAHGD 171 + + I + ++ + + ++ GLM W Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183 Query: 172 RARLETETETACQAVKLLVASY 193 L + A V +L+ Y Sbjct: 184 SFDL---KKEARDYVAILLEMY 202
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 75.6 bits (186), Expect = 4e-16 Identities = 35/209 (16%), Positives = 82/209 (39%), Gaps = 9/209 (4%) Query: 590 TTINRVVAAVKAFRSEYPQPGLSIRLASGNAGVLAAINEEVEKSETPMLLYVYAAIALLV 649 T + A + + +PQ G+ + + EV K+ L + L++ Sbjct: 301 DTAKAIKAKLAELQPFFPQ-GMKVLYPYDTTPFVQLSIHEVVKT----LFEAIMLVFLVM 355 Query: 650 FAVYRDLRAVLVCCLPLTIGTFIGYWFMKELQIGLTIATLPVMVLAVGIGVDYAFYIYNR 709 + +++RA L+ + + + + + + T+ MVLA+G+ VD A + Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 710 LQLHLAHGQSITK-AVEHALLEVGVATIFTAITLAVGVATWAF---SDLKFQADMGKLLA 765 ++ + + K A E ++ ++ A + A+ L+ AF S + Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 766 FMFIVNMVMAMTVLPAFAVWLERVFPRKR 794 +++++A+ + PA L + + Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEH 504 Score = 44.4 bits (105), Expect = 2e-06 Identities = 40/241 (16%), Positives = 83/241 (34%), Gaps = 14/241 (5%) Query: 208 KELRQQFEDGDFEVQIIGFAKQIGDIADGASAVLEFCLLALLLTAAAVYWYCHSLRFTLL 267 EL+ F G ++++ + V++ A++L +Y + ++R TL+ Sbjct: 311 AELQPFFPQG---MKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLI 367 Query: 268 ALVCSLASLVWQFGSLRLLGYGLDPLAVLVPFLVFAIGVSHGVQQINFIVREIAIGKSAE 327 + L+ F L GY ++ L + L + V + + + R + K Sbjct: 368 PTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPP 427 Query: 328 AAA----RSSFTGLLIPGTLALVTALVSFVTLLLIPIPMVRELAITASLGVAYKIITNLL 383 A S G L+ + L + + R+ +IT +A ++ L+ Sbjct: 428 KEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALI 487 Query: 384 MLPLLASMLRIDDKYAAAQEVSRQRR-SRWL-RGLARLAE--WRNAQWVLGVALVIFLVA 439 + P L + L K +A+ + W + +LG L+ Sbjct: 488 LTPALCATLL---KPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIY 544 Query: 440 I 440 Sbjct: 545 A 545
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.006 Identities = 19/113 (16%), Positives = 37/113 (32%), Gaps = 9/113 (7%) Query: 258 RAAIGSAGAGMNGFRRSHLEALTTQRLMGRLAGSPGVATIDQVRMVSLMTQDARAARQFV 317 R + R +E + + A + + + ++ R Sbjct: 364 RLTALYPQDVI---TREIIE-NELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 318 LNTLGRLATEPTVLQQS-----LHAFLANGCNITQTAEVLGTHRNTLLRRLER 365 + L VL + L A A N + A++LG +RNTL +++ Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>cloacin#Cloacin signature. Length = 551 Score = 37.8 bits (87), Expect = 5e-05 Identities = 34/167 (20%), Positives = 68/167 (40%), Gaps = 11/167 (6%) Query: 160 DELQAQRDEARTQLTEVD--HLLQESRKQAEQARSEQQRYTRDV------EDRAYREIDR 211 D+++ ++DE + E D H ++ + + E+AR+E + DV + +A + + Sbjct: 294 DQVKQRQDEENRRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNS 353 Query: 212 AREESKALGAQLKDAQGRLSIAQRGMEEHQLVLTDTRDQLQAARSQGQLLGAQLTQVQQR 271 + E A L DA + R + + Q A + Q + Q Sbjct: 354 RKSELDAANKTLADAIAEIKQFNRFAHDP---MAGGHRMWQMAGLKAQRAQTDVNNKQAA 410 Query: 272 ASEAGEYISRLEAALQAAREDLAEARERAVAAEARIEVLASRPRRST 318 A + S +AAL +A E + ++ +AE + ++PR+ Sbjct: 411 FDAAAKEKSDADAALSSAMESRKKKEDKKRSAENNLNDEKNKPRKGF 457
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 75.0 bits (184), Expect = 1e-17 Identities = 45/184 (24%), Positives = 75/184 (40%), Gaps = 18/184 (9%) Query: 53 PQRVVAFDMSELDTLDQLGAPVVGIAKDYVAGFLAKYR---DDP----KVADVGTTIQPN 105 P R+VA + ++ L LG G+A YR +P V DVG +PN Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVAD------TINYRLWVSEPPLPDSVIDVGLRTEPN 88 Query: 106 LERLHALKPDLILISPLQAQSYQELSQIAPTVHYDIDMDNRQGNVIDTAKQHLLTVGRIL 165 LE L +KP ++ S S + L++IAP ++ + + A++ L + +L Sbjct: 89 LELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQP---LAMARKSLTEMADLL 145 Query: 166 GKEDRARETAARIDA--KVAQVRQVTDGRPEKALVVLHNNGAFTAYGVRSRYGFIFDTLG 223 + A A+ + + + R V G L L + +G S + I D G Sbjct: 146 NLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYG 205 Query: 224 VKPA 227 + A Sbjct: 206 IPNA 209
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 332 bits (852), Expect = e-117 Identities = 144/302 (47%), Positives = 187/302 (61%), Gaps = 18/302 (5%) Query: 1 MTIPTIHDYAMPQRASYPANKTQWQPDPARAVLLIHDMQRYFLRFYQPDGALLTALVDNL 60 M IP I Y MP + P NK W PDP RAVLLIHDMQ YF+ + + +T L N+ Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 SRLIHWAREQGIPVVYTAQPHEQPPEDRALLNAMWGPGLPAASPEQQPIIDALAPQAGDT 120 +L + + GIPVVYTAQP Q P+DRALL WGPGL + P ++ II LAP+ D Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGL-NSGPYEEKIITELAPEDDDL 119 Query: 121 VLTKWRYSAFQRSDLLERMRTWQRDQLLIGGVYAHIGCMITAADAFMNDIQAFLVGDAVA 180 VLTKWRYSAF+R++LLE MR RDQL+I G+YAHIGC++TA +AFM DI+AF VGDAVA Sbjct: 120 VLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVA 179 Query: 181 DFSEEEHRLALKYVATRCGHVTDTTALLTQ----PAGETTRDWLHGR--------VRQMI 228 DFS E+H++AL+Y A RC T +LL Q PA G+ +R+ I Sbjct: 180 DFSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQI 239 Query: 229 -----EDDSDLDPQESLIFYGLDSLQVMKLAAELKQRGIAVSFEELANAPTLDGWWSLMQ 283 E D+ QE L+ GLDS+++M L + ++ G V+F ELA PT++ W L+ Sbjct: 240 AELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299 Query: 284 AR 285 R Sbjct: 300 TR 301
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 256 bits (655), Expect = 3e-88 Identities = 104/252 (41%), Positives = 143/252 (56%), Gaps = 12/252 (4%) Query: 8 GRRVLVTGAASGIGRCVAQQFLEEGAEVIGLDCEEADVPFAL------------LHVDLT 55 G+ +TGAA GIG VA+ +GA + +D + + D+ Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 56 DPADVQRVCDRLKEQAQYLDVLVNVAGVLRLGRSDEVSCEDWLRCLDVNVSAPFYLMRQW 115 D A + + R++ + +D+LVNVAGVLR G +S E+W VN + F R Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 116 TPVFRRQRRGAIVNVASNAAHVPRLNMAAYCTSKAALVSLSHCVGLELAPYGVRCNVVSP 175 + +R G+IV V SN A VPR +MAAY +SKAA V + C+GLELA Y +RCN+VSP Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 176 GSTRTPMLAGMLGDPAGERQLVDGLPGQYKLGVPLGKIATPDDIANVVLFLASEQAGHVT 235 GST T M + D G Q++ G +K G+PL K+A P DIA+ VLFL S QAGH+T Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 236 LQDIVVDGGATL 247 + ++ VDGGATL Sbjct: 248 MHNLCVDGGATL 259
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 29.4 bits (66), Expect = 0.041 Identities = 23/88 (26%), Positives = 37/88 (42%), Gaps = 17/88 (19%) Query: 235 AKGGVTVIDVPSRRMLKSFVTGSGHHEIAFSADSRFAFVSNRDV----GTLSVIDTAQMR 290 + G+ +D SG A+ AD RF +S V L+ +D + Sbjct: 38 GRVGMIEMD-----------LASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQ 86 Query: 291 LVKTLEVGPQPLSVAYSPLSQAVYVVDG 318 L + + Q L V YSP+S+ ++ DG Sbjct: 87 LERKIHYRQQDL-VDYSPVSEK-HLADG 112
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 33.4 bits (76), Expect = 0.012 Identities = 42/199 (21%), Positives = 70/199 (35%), Gaps = 25/199 (12%) Query: 1323 GVKWLQNGSGFGNSSNSGWKSSQMIGISEQLGFMAPVSMISSSAATNGDYLYSLDAALEG 1382 G++W +G +NSG S I + Q + ++ SS A+ + + G Sbjct: 365 GIQWANKNAGMTQFTNSGLPISTAIAGANQ--YNKDGTVSSSLASALSSF----NGIAAG 418 Query: 1383 YWNGIWGIMRNYTAQRADLFPLPNNPQPVAMRN---TVNFDGICP-----KTTANANGIG 1434 ++ G W ++ + L P V + N T N P +TT+ N Sbjct: 419 FYQGNWAMLLTALSSSTKNDIL-ATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFN 477 Query: 1435 T--RPTVKRSYEVVAALANDILENRSSVTISDPNGVGQHVGGPLKANGGTLVFNSRRTSI 1492 T R TV +V I E S + + ++ FN+R + Sbjct: 478 TVERKTVGIKLKVKPQ----INEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVN- 532 Query: 1493 PLVSGVDPEDGETFTIGGH 1511 + V GET +GG Sbjct: 533 ---NAVLVGSGETVVVGGL 548
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 1e-04 Identities = 13/51 (25%), Positives = 23/51 (45%), Gaps = 1/51 (1%) Query: 91 VAQAWQGRGVGSRLMAAILDIADNWMNLRRVQLTVYADNEPALALYRKFGF 141 VA+ ++ +GVG+ L+ ++ A + + L N A Y K F Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKE-NHFCGLMLETQDINISACHFYAKHHF 146
>LIPOLPP20#LPP20 lipoprotein precursor signature. Length = 175 Score = 29.0 bits (64), Expect = 0.002 Identities = 26/108 (24%), Positives = 52/108 (48%), Gaps = 6/108 (5%) Query: 1 MAVVASLLLAGCAHDPDIRAGRDN-TFGMTSKSPPEYL--NCIK-AELPDTATTYVVRNQ 56 M+VVA++++ GC+H P + N + +K P+++ + K A+ + ++ R + Sbjct: 11 MSVVAAMVIVGCSHAPKSGISKSNKAYKEATKGAPDWVVGDLEKVAKYEKYSGVFLGRAE 70 Query: 57 DALELFVASTDPNKAEGLVKVQGAAGRQQFSAYQRDAWYDKGRLLDAA 104 D + N+A + AA + S Q+D +K R +DA+ Sbjct: 71 DLITNNDVDYSTNQATAKARANLAANLK--STLQKDLENEKTRTVDAS 116
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.015 Identities = 21/79 (26%), Positives = 32/79 (40%), Gaps = 16/79 (20%) Query: 292 IQLAEVKPSSRVSPFIRFEQ--TKKLHRQAVTVEKMAKAFDDKVLFKDFSFTIEAGERVA 349 + + P +R+ Q K + V A+ + F D+S +E Sbjct: 555 VHVLGKTPDDYKPRRLRYLQLVGKYILMGHV-----ARVMEPGCKF-DYSVVLE------ 602 Query: 350 IIGPNGIGKTTLLRTLVGE 368 G GIGK+TL+ TLVG Sbjct: 603 --GTGGIGKSTLINTLVGL 619
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 91/397 (22%), Positives = 136/397 (34%), Gaps = 32/397 (8%) Query: 12 QILSIVLYTFIAFLCIGLPIAVLPGHVHDQLGFGAVIA--GLTIGLQYLATLLSRPFAGR 69 ++ I+ + + IGL + VLPG + D + V A G+ + L L P G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 70 VADTLGGKRAIRYGLYGIAGCGVLTLLSAWALALPWLSLALLLGGRLLLGIAQGLIGVAT 129 ++D G + + L +AG V + A A L L + GR++ GI VA Sbjct: 66 LSDRFGRRPVL---LVSLAGAAVDYAIMATAPFLWVLYI-----GRIVAGITGATGAVAG 117 Query: 130 LSWGIGQVGPEHT-ARVISWNGIASYGAIAIGAPAGVLLVDGLSFA--VLGPALLGLALL 186 I + AR + + G G L+ A AL GL L Sbjct: 118 AY--IADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFL 175 Query: 187 ALLVLRTRPDVVVVRGERLP--------FWSAFGRVAPCGVGVGLTLASIGYGTLTTFVT 238 L R R W+ V + V + +G +V Sbjct: 176 TGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 239 LYYLERGWVGA--AWCLSAFGLCFILSRLLFVNAVNRYGGYNVAIAC-MATEVLGLSLLW 295 W L+AFG+ L++ + V G A+ M + G LL Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA 295 Query: 296 LAPSPLWAMVGAGLTGFGLSLVYPALGVEAIRQVPSSSRGAGLGAYAVFFDLALAIAGPV 355 A A L G + PAL RQV +G G+ A L +I GP+ Sbjct: 296 FATRGWMAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLT-SIVGPL 353 Query: 356 MGAV--AVHLGYASIFCVAALLALSGVGLTLLLARRG 390 + A + + + A AL + L L RRG Sbjct: 354 LFTAIYAASITTWNGWAWIAGAALYLLCLPAL--RRG 388
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 29.4 bits (65), Expect = 0.046 Identities = 26/91 (28%), Positives = 39/91 (42%), Gaps = 9/91 (9%) Query: 20 PADLTPPAQ--LP------WLRRLAARLLGRGLSRLQAQ-HRDSWFLGHATGQRNGHADG 70 P DL PP +P + A L + L++LQ Q H + G A G++ GH G Sbjct: 12 PDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQG 71 Query: 71 LREGYERGRVDGYEAGRQVLVIRDTRPEQVV 101 +EG +G G + R +Q+V Sbjct: 72 YQEGLAQGLEQGLAEAKSQQAPIHARMQQLV 102
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 454 bits (1169), Expect = e-159 Identities = 169/491 (34%), Positives = 253/491 (51%), Gaps = 35/491 (7%) Query: 4 SILVVEDDEILADNIRTYLGLKGFEVTVCHSAELALEQIKRARPDAVLTDNSLPGMSGHD 63 +ILV +DD + + L G++V + +A I D V+TD +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LLRTLVAQAPELKVIMMTGYGNVEDAVLAMKEGAFHYLTKPVVLAELKLMLDKALAAERM 123 LL + P+L V++M+ A+ A ++GA+ YL KP L EL ++ +ALA + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 124 ERTLSFYQEREAQKSGLQALIGESPAMLELKHTLRQLLDAERRMASGDLPPVLVEGETGT 183 + E L+G S AM E+ L +L DL +++ GE+GT Sbjct: 125 RP-----SKLEDDSQDGMPLVGRSAAMQEIYRVLARL-------MQTDLT-LMITGESGT 171 Query: 184 GKELVARALHFDGSRAKGPFIEFNCASIPANLLEAELFGHEKGAFTDAKERRVGLVEAAD 243 GKELVARALH G R GPF+ N A+IP +L+E+ELFGHEKGAFT A+ R G E A+ Sbjct: 172 GKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAE 231 Query: 244 GGTLFLDEIGEMDLVLQAKLLKLLEDRTIRRIGAVKERKVDLRVISATNCNLEQMVQQGK 303 GGTLFLDEIG+M + Q +LL++L+ +G + D+R+++ATN +L+Q + QG Sbjct: 232 GGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGL 291 Query: 304 FRRDLFFRLRIIALKVPRLHARGQDILLLARHFLAHHGRRYGKPNLRFSAEAEALMLGYG 363 FR DL++RL ++ L++P L R +DI L RHF+ + G RF EA LM + Sbjct: 292 FREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQA-EKEGLDVKRFDQEALELMKAHP 350 Query: 364 WPGNVRELRNMLEQTVLLAPGEVIGAHQLNL-CLTLVDEPPAQPGQVLAFEAPRHEPPGT 422 WPGNVREL N++ + L P +VI + + + + P + + + Sbjct: 351 WPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEE 410 Query: 423 A--------------------SLPDMERDMVCRTLDRTDWNVTKSARLLGLSRDMLRYKI 462 L +ME ++ L T N K+A LLGL+R+ LR KI Sbjct: 411 NMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKI 470 Query: 463 EKLGLTRPDKR 473 +LG++ Sbjct: 471 RELGVSVYRSS 481
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 175 bits (445), Expect = 9e-60 Identities = 59/141 (41%), Positives = 88/141 (62%), Gaps = 7/141 (4%) Query: 3 RNIHSQRGFTLLELLVVLVVLGLLAGIVAPKYFSQLGRSEAKVARAQIEGLGKALDLYRL 62 R QRGFTLLE++VV+V++G+LA +V P +++ + A + I L ALD+Y+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 63 EVGHYPSSEQGLQALVAAPS---GEARWSGPYLQKAVPQDPWGRPYIYKQPGENGGEYDL 119 + HYP++ QGL++LV AP+ A ++ K +P DPWG Y+ PGE+G YDL Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGA-YDL 120 Query: 120 LSMGKDGQPGGDGENAEITSW 140 LS G DG+ G + +IT+W Sbjct: 121 LSAGPDGEMGTED---DITNW 138
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 243 bits (622), Expect = 4e-79 Identities = 130/403 (32%), Positives = 207/403 (51%), Gaps = 14/403 (3%) Query: 3 YQLKALGSQG-VVQMQVEAEDSDQARRQAEDQGLRVLSVR----------SRGLALRR-- 49 Y +AL +QG + EA+ + QAR+ ++GL LSV S GL+LRR Sbjct: 4 YHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKI 63 Query: 50 RPAAFDLMLFSQELATLLGAGLPLIDALESLAEKAPGGATRKTLAQLVGQLYEGRSLSQA 109 R + DL L +++LATL+ A +PL +AL+++A+++ + +A + ++ EG SL+ A Sbjct: 64 RLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADA 123 Query: 110 LAQQPRVFPALYVALVQSSERTGALGDALNRYIGYRQRLDLVRQKLVGASVYPLLLLLVG 169 + P F LY A+V + E +G L LNR Y ++ +R ++ A +YP +L +V Sbjct: 124 MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVA 183 Query: 170 GGVVLFLLGYVVPRFSLVFEGMGSELPWLSRVLMQIGLFLHAQQLPLGLGTLAGLGALVA 229 VV LL VVP+ F M LP +RVLM + + + L LAG A Sbjct: 184 IAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRV 243 Query: 230 LRRHPALRRGAGRLLRRLPALHQRLVMYELARFYRSLGILLQGGIPILTALGMARGLLGS 289 + R R R L LP + + AR+ R+L IL +P+L A+ ++ ++ + Sbjct: 244 MLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSN 303 Query: 290 SAA-EGLEQASRRVAEGLPLSDALLAGQLVTPVSLRLLRAGEQSGNLGEMLERCADFHDQ 348 A L A+ V EG+ L AL L P+ ++ +GE+SG L MLER AD D+ Sbjct: 304 DYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDR 363 Query: 349 EIGRWVEWFVKLFEPLLMTFIGLLIGLIVILMYMPIFELASSI 391 E + + LFEPLL+ + ++ IV+ + PI +L + + Sbjct: 364 EFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.013 Identities = 22/122 (18%), Positives = 46/122 (37%), Gaps = 19/122 (15%) Query: 56 WSMHFIGMLAFSL----------PIELGYDTTLTVLSLLIAVASSGFALWLVSQPRLPWL 105 W IG ++L +L +SL+ V + + ++ R WL Sbjct: 13 WYCQGIGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIK---RQGWL 69 Query: 106 QLVFGALIMGTGIACMHYMGM------AALRMQPGIDYDPTLFGVSLAIAVGASAAALWI 159 +L G +I+ AC+ + + R+ I+ P F + LA+++ + + Sbjct: 70 KLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTF 129 Query: 160 AF 161 + Sbjct: 130 MW 131
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 5e-09 Identities = 37/204 (18%), Positives = 73/204 (35%), Gaps = 21/204 (10%) Query: 65 AQVSGQLKSLKVKLGDKVSEGQWLAEIDPL-----VPQNTLRQAEVDEEKLQAERRSVQA 119 A+ L + E L + L + ++ + + E + E R ++ Sbjct: 214 AERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKS 273 Query: 120 KLKQARRVYERYEVLQDDESIS--RQDFESAESEFEVQQANLRSLDAQIKSARVQIDTAR 177 +L+Q E+L E Q F++ + LR I +++ Sbjct: 274 QLEQIES-----EILSAKEEYQLVTQLFKNEILD------KLRQTTDNIGLLTLELAKNE 322 Query: 178 VNLGYTRIVAPINGHVVGI-VTQEGQTVISNQLAPVILKLADLDTMTIKAQVSEADVIHI 236 + I AP++ V + V EG V + + +++ + + DT+ + A V D+ I Sbjct: 323 ERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE--TLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 237 SPGQQVYFTILGDDQRYYAKLRGT 260 + GQ + Y L G Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGK 404 Score = 48.3 bits (115), Expect = 3e-08 Identities = 27/165 (16%), Positives = 57/165 (34%), Gaps = 31/165 (18%) Query: 43 GDIENAVLATGTL--EGIRQVDVGAQVSGQLKSLKVKLGDKVSEGQWLAEIDPLVP---- 96 G +E A G L G + + + +K + VK G+ V +G L ++ L Sbjct: 78 GQVEIVATANGKLTHSGRSKE-IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADT 136 Query: 97 ---QNTLRQAEVDEEKLQAERRS-------------------VQAKLKQARRVY--ERYE 132 Q++L QA +++ + Q RS V + E++ Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196 Query: 133 VLQDDESISRQDFESAESEFEVQQANLRSLDAQIKSARVQIDTAR 177 Q+ + + + +E A + + + + ++D Sbjct: 197 TWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFS 241
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 27.8 bits (61), Expect = 0.031 Identities = 15/68 (22%), Positives = 26/68 (38%), Gaps = 1/68 (1%) Query: 127 DGIFDGDLVGIRQQGEARDGQIVVARLDGEVTIKRLQRTRDGYRLLPRNPAYAPIDVSPG 186 G + G + I E +G+ + V L+ D LL RNP YA + + Sbjct: 206 SGNWKGPVTEI-TTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAAS 264 Query: 187 RDFFIEGV 194 + + + Sbjct: 265 AEQGAQAL 272
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 30.9 bits (69), Expect = 0.002 Identities = 20/73 (27%), Positives = 29/73 (39%) Query: 1 MHSGIEIRVARPEDAEEIQIIYAPIVLNTAISFEEAVPSVEQMCERISTTLQTYPYLVAV 60 M + + P+D Q + PIV EEA PS+EQ ++ Y + Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 REGRVVGYAYASQ 73 EGR G+ Q Sbjct: 61 AEGRQQGHKQGYQ 73
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 39.4 bits (92), Expect = 3e-05 Identities = 31/223 (13%), Positives = 67/223 (30%), Gaps = 23/223 (10%) Query: 211 NSADRTYRVDTLTLTTTRSGSASFDKDSSYSKDSSASSSWDAAGSNSWNASGSNSSSAS- 269 + T Y+ + + + + S S Sbjct: 490 ADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSH 549 Query: 270 ----GSRSHDSSSSASGSLNASLDASANGSVTHTQDFGRHERSRTDSFDASLSASIDTSY 325 G+ + D A + D + S + T++ + R + +L+ +I S+ Sbjct: 550 QTYWGTSNVDEQFQAGLNTAFE-DINWTLSYSLTKNAWQKGRDQM----LALNVNIPFSH 604 Query: 326 DKSHEKSSSSSYEKARDSAFEKAYDSSYEKSGSASNESSKSGSKSYSESSSYDLSNTVSF 385 + S + A +Y S++ +G +N + G+ + SY + Sbjct: 605 WLRSDSKSQWRHASA-------SYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSV------ 651 Query: 386 QVLTPTGWANPVTNTATLSGSVNGGSGNLGVNVAAGVGNQQSN 428 Q G +T + + GG GN + + +Q Sbjct: 652 QTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLY 694 Score = 30.2 bits (68), Expect = 0.019 Identities = 22/167 (13%), Positives = 51/167 (30%), Gaps = 13/167 (7%) Query: 126 FGSASATADVRQYSNNNKVNNYGTTNSGIMSGSGNNGSGNMGINIAGGDLNQQKNTMAIA 185 + + + Y + V+ ++ + + + + ++ + ++ M Sbjct: 540 TSTLYLSGSHQTYWGTSNVDEQFQAG---LNTAFEDINWTLSYSLTKNAWQKGRDQMLAL 596 Query: 186 NSNAPLGNATATASADQNGPGLVVNNSADRTYRVDTLTLTTTRSGSASFDKDSSYSKDSS 245 N N P + + S Q + S T G+ D + SYS + Sbjct: 597 NVNIPFSHWLRSDSKSQWRHA-SASYSMSHDLNGRM-TNLAGVYGTLLEDNNLSYSVQTG 654 Query: 246 ASSSWDAAGSNSWNAS-------GSNSSSASGSRSHDSSS-SASGSL 284 + D ++ A+ G+ + S S SG + Sbjct: 655 YAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGV 701
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 394 bits (1014), Expect = e-136 Identities = 146/379 (38%), Positives = 196/379 (51%), Gaps = 36/379 (9%) Query: 98 FDFHTLPFDVSRVQVTLGRAFGMARLRGKGTVRVDEPEHELLGESRPIRELRKLLGKLAP 157 +D+ PFD++ + +GRA + R + L+G S ++E+ ++L +L Sbjct: 99 YDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQ 158 Query: 158 TESPVLIRGESGTGKELVARTLHRQSQRRDKPFIAINCGAIPEHLIQSELFGHEKGAFTG 217 T+ ++I GESGTGKELVAR LH +RR+ PF+AIN AIP LI+SELFGHEKGAFTG Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTG 218 Query: 218 AHQRKVGRIEAANGGTLFLDEIGDLPLELQANLLRFLQEKHIERVGGNQPIAVDVRVLAA 277 A R GR E A GGTLFLDEIGD+P++ Q LLR LQ+ VGG PI DVR++AA Sbjct: 219 AQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAA 278 Query: 278 THVDLEKAIALARFREDLYYRLNVLQVVTAPLRDRHGDLSMLASHFSQFYSAETGRRPRS 337 T+ DL+++I FREDLYYRLNV+ + PLRDR D+ L HF Q E G + Sbjct: 279 TNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKR 337 Query: 338 FSEGALAAMGRHDWPGNVRELANRVRRGLVLAEGRQIEAQDLGLQ--------------- 382 F + AL M H WPGNVREL N VRR L I + + + Sbjct: 338 FDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAA 397 Query: 383 --------------------ELQEQDQPLGTLEDYKHRAERQALCDVLNRHSDNLSIAAK 422 + P G + E + L N AA Sbjct: 398 RSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAAD 457 Query: 423 VLGVSRPTFYRLLHKHQIR 441 +LG++R T + + + + Sbjct: 458 LLGLNRNTLRKKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.8 bits (106), Expect = 3e-07 Identities = 42/159 (26%), Positives = 61/159 (38%), Gaps = 14/159 (8%) Query: 34 VLIEGPRGMAKSTLARGLADL--LGDGPFVTLPLGATEERLVGTLDLDAALG--QGQARF 89 ++I G G K +AR L D +GPFV + + A L+ + G G Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 90 SPGVLAHADGGVLYVDEVNLLPDPLVDLLLDVAASGTNRIERDGISHRHAARFVLIGTMN 149 S G A+GG L++DE+ +P LL V G G + ++ N Sbjct: 223 STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGE--YTTVGGRTPIRSDVRIVAATN 280 Query: 150 P------EEGELRPQLLDRFGLNVALEGLPAPQARQQII 182 +G R L R LNV LP + R + I Sbjct: 281 KDLKQSINQGLFREDLYYR--LNVVPLRLPPLRDRAEDI 317
>PF07132#Harpin protein (HrpN) Length = 356 Score = 40.4 bits (94), Expect = 4e-06 Identities = 42/134 (31%), Positives = 53/134 (39%), Gaps = 2/134 (1%) Query: 4 SDLLEQLLRAGQGSQAQQGRGGMSSQDGLGGLGGLLGGLLGGGSTAGGSGGLGGLLGGIL 63 S++ EQL G GLGGLG LGGL GG G GGLG LG L Sbjct: 45 SNIAEQLSDIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGL 104 Query: 64 GGSGGNAGASTQGRSAGGVNYAALASLGMMAFQAYQSWQRSQAAAPQQAVRTVDQLSGPE 123 G + G G AG A +G + F A + + Q + Q S PE Sbjct: 105 GSALGGGLGGALG--AGMNAMNPSAMMGSLLFSALEDLLGGGMSQQQGGLFGNKQPSSPE 162 Query: 124 AEDHSHAILRALIA 137 ++ + AL A Sbjct: 163 ISAYTQGVNDALSA 176
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.6 bits (69), Expect = 0.009 Identities = 19/76 (25%), Positives = 30/76 (39%), Gaps = 9/76 (11%) Query: 17 AEVSDSMSLEAFFKG-MAVTRAVERLA-LDGVLDVCLANASFQIRF--DPDRIA-----P 67 VSD+ + + L+ L+GV DV L A + +R D D + P Sbjct: 141 GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTP 200 Query: 68 ADLLEAVKGAEAQAVA 83 D++ +K Q A Sbjct: 201 VDVINQLKVQNDQIAA 216
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 2e-05 Identities = 9/48 (18%), Positives = 18/48 (37%) Query: 33 SADTVIGLIEVMKQFSELTAGTAGRLDAFLVEDGDPVEPGQVIATLED 80 T G + + E+ + +V++G+ V G V+ L Sbjct: 82 IVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA 129
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 45.2 bits (107), Expect = 2e-07 Identities = 29/129 (22%), Positives = 51/129 (39%), Gaps = 18/129 (13%) Query: 6 FVTGGSGFVGQHLLARLTATGHKVWVLMRTPANLD-----RLREQVSRLGGNPACIHAVE 60 VTG +GF+G H+ RL GH+V + NL+ L++ L P + Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLNDYYDVSLKQARLELLAQPG-FQFHK 58 Query: 61 GDIS-REGLGLSEADKQRVSSASVAFHLAAQFSWGLTMERAR---EVNVQGALRVARLAA 116 D++ REG+ A F + + ++E + N+ G L + Sbjct: 59 IDLADREGMTDLFASGH----FERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCR 114 Query: 117 SQRIRLLMV 125 +I+ L+ Sbjct: 115 HNKIQHLLY 123
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.5 bits (61), Expect = 0.030 Identities = 13/33 (39%), Positives = 19/33 (57%), Gaps = 3/33 (9%) Query: 4 VMIIGQPGSGKSTLAR---KLGERTGLPVVHID 33 +MI G+ G+GK +AR G+R P V I+ Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAIN 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 28.6 bits (64), Expect = 0.046 Identities = 34/185 (18%), Positives = 62/185 (33%), Gaps = 24/185 (12%) Query: 52 MPYLIEE---EGYTRGQLGVAISAIAIAYGLSKFLMGLVSDRSNPRYFLPFGLLISAGVM 108 +P L+ + G+ ++ A+ ++G +SDR R L L +A Sbjct: 28 LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDY 87 Query: 109 FIFGFAHWATSSVTIMFVLLFINGWAQGMGWPPSGRTMVHWWSQKER-------GGVVSV 161 I A + ++++ + G G +G + ER Sbjct: 88 AIMATAP----FLWVLYIGRIVAG-ITGATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 162 WNVAHNVGGGLIGPLFLLGLGWTNDWHAAFYVPAAVAVLVAVFAFATMRDTPQSVGLPPV 221 VA V GGL+G HA F+ AA+ L + + ++ + P Sbjct: 143 GMVAGPVLGGLMGGFSP---------HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLR 193 Query: 222 EQYKN 226 + N Sbjct: 194 REALN 198
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (294), Expect = 5e-34 Identities = 79/257 (30%), Positives = 119/257 (46%), Gaps = 11/257 (4%) Query: 3 LAGKVAIITGASSGIGRAAATLFARHGANLVLTARRQAELEQLTADIAAAGQGRAIAVAG 62 + GK+A ITGA+ GIG A A A GA++ +LE++ + + A + A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR-HAEAFPA 64 Query: 63 DITDAALVRELVDVAVARFGGLDIAFNNAGTLGELAAVPELSLEGWQHTLHTNLTSAFLC 122 D+ D+A + E+ G +DI N AG L + LS E W+ T N T F Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 123 AQAQIPALLARGGGSLIFTSTFVGHSVGMPGMAAYAASKAGLVGLVQVIAAEQGCRGIRA 182 +++ ++ R GS++ + MAAYA+SKA V + + E IR Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRT-SMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 183 NALLPGGTDTPMGRSAMNSAEARAHVEGLHA--------LKRLARPQEIAEAALFLASEA 234 N + PG T+T M S V LK+LA+P +IA+A LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 235 SSFMTGAAMVVDGGVSV 251 + +T + VDGG ++ Sbjct: 243 AGHITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 5e-18 Identities = 28/122 (22%), Positives = 52/122 (42%), Gaps = 2/122 (1%) Query: 2 IRVLVVDDHDLVRTGITRMLADIDGLQVVGEADSGESALKLARELKPDVVLMDVKMPGIG 61 +LV DD +RT + + L+ G V + + + D+V+ DV MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEATRKLLRSHPDIKVVAVTVCEEDPFPTRLLQAGAAGYLTKGAGLDEMVQAIRLAFAG 121 + ++ ++ PD+ V+ ++ + + GA YL K L E++ I A A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 QR 123 + Sbjct: 122 PK 123
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.002 Identities = 13/69 (18%), Positives = 23/69 (33%), Gaps = 1/69 (1%) Query: 196 QATVAGNAQVISMPDNGYVKYLLPAGASEVQAGQPLANIS-TQLATSFTSPADMKALADL 254 + T +G ++ I +N VK ++ V+ G L ++ A L Sbjct: 89 KLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL 148 Query: 255 APGDLQALL 263 Q L Sbjct: 149 EQTRYQILS 157
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.002 Identities = 11/35 (31%), Positives = 18/35 (51%), Gaps = 2/35 (5%) Query: 30 LIAVPLFILGALLVLSGLFGLDLSQIA-VGIIALV 63 ++ VPL I+G LL + LF VG++ + Sbjct: 901 MLVVPLGIVGVLLAAT-LFNQKNDVYFMVGLLTTI 934 Score = 29.0 bits (65), Expect = 0.004 Identities = 13/71 (18%), Positives = 33/71 (46%), Gaps = 8/71 (11%) Query: 30 LIAVPLFILGALLVLSGLFGLDLSQIAVGIIALVAGLG-------LQRQGHRLEDEQPEP 82 IAVP+ +LG +L+ FG ++ + + + L GL ++ + +++ P Sbjct: 369 TIAVPVVLLGTFAILA-AFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPP 427 Query: 83 FSGRKDAVQRL 93 + ++ ++ Sbjct: 428 KEATEKSMSQI 438
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (301), Expect = 2e-39 Identities = 48/88 (54%), Positives = 62/88 (70%) Query: 2 NKSELIDAIAASADIPKAVAGRALDAVIESVQGALQKGDDVVLVGFGTFSVKDRAERTGR 61 NK +LI +A + ++ K + A+DAV +V L KG+ V L+GFG F V++RA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKAIKIAAAKVPGFKAGKGLKDAV 89 NPQTG+ IKI A+KVP FKAGK LKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.025 Identities = 13/83 (15%), Positives = 29/83 (34%), Gaps = 6/83 (7%) Query: 292 DWLVQVPWKAQSKVRLDLAKAEEILDADHYGLEEVKERILEYLAVQKRVKKIRGP----- 346 DW+ W ++ L D+ +++ + V ++ P Sbjct: 537 DWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFD 596 Query: 347 -VLCLVGPPGVGKTSLAESIAAA 368 + L G G+GK++L ++ Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 315 bits (809), Expect = e-100 Identities = 112/446 (25%), Positives = 190/446 (42%), Gaps = 68/446 (15%) Query: 360 RAIGQRIGAGKVRV-INDVSEMDKVQPGDVLVSDMTDPDWEPVMK-RASAIVTNRGGRTC 417 R + +R+ + V ++ + + ++ D+T D + K T+ GGRT Sbjct: 132 RDVSKRVLGHLIGVETGSLATIA--EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTS 189 Query: 418 HAAIIARELGIPAVVGCGNATQVLKDGQGVTVSCAEG---------DTGFIFEGELGFDV 468 H+AI++R L IPAVVG T+ ++ G V V EG + E F+ Sbjct: 190 HSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEK 249 Query: 469 KQNSVDAMPELP--------FKIMMNVGNPDRAFDFAQLPNAGVGLARLEFIINRMIGVH 520 ++ + P ++ N+G P G+GL R EF+ Sbjct: 250 QKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY------- 302 Query: 521 PKALLNYAGLPPELKESVDKRIAGYDDPVGFYVEKLVEGISTLAAAFYPKKVIVRLSDFK 580 ++ LP E E+ E + K V++R D Sbjct: 303 ----MDRDQLPTE--------------------EEQFEAYKEVVQRMDGKPVVIRTLDIG 338 Query: 581 SNEYANLIGGKLYEPEEENPMLGFRGASRYISESFRDCFELECRALKRVRNEMGLTNVEI 640 ++ + L P+E NP LGFR + + +D F + RAL R N+++ Sbjct: 339 GDKELSY----LQLPKELNPFLGFRAIRLCLEK--QDIFRTQLRALLRAS---TYGNLKV 389 Query: 641 MVPFVRTLGEASQVVDLLAENG---LARG---DNGLRVIMMCELPSNAILAEEFLEYFDG 694 M P + TL E Q ++ E L+ G + + V +M E+PS A+ A F + D Sbjct: 390 MFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDF 449 Query: 695 FSIGSNDLTQLTLGLDRDSGIIAHLFDERNPAVKKLLANAIAACNKAGKYIGICGQGPSD 754 FSIG+NDL Q T+ DR + +++L+ +PA+ +L+ I A + GK++G+CG+ D Sbjct: 450 FSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD 509 Query: 755 HPDLAKWLMEQGIESVSLNPDSVLET 780 L+ G++ S++ S+L Sbjct: 510 -EVAIPLLLGLGLDEFSMSATSILPA 534
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.4 bits (105), Expect = 6e-07 Identities = 71/371 (19%), Positives = 128/371 (34%), Gaps = 47/371 (12%) Query: 75 FIARPFGGVLFGYLGDRFGRKHVLVITFCMMGLCTMLIGLIPGYATIGIWAPIL--LVII 132 F P G L DRFGR+ VL+++ L G YA + AP L L I Sbjct: 57 FACAPVLGAL----SDRFGRRPVLLVS---------LAGAAVDYAIMAT-APFLWVLYIG 102 Query: 133 RIIQGLGAGAELSGAAVTSYEHASEGKRGSQGAWPALGLNLGLLLSSLTVYLLTMNGNEF 192 RI+ G+ GA + A + +R + + G++ + Sbjct: 103 RIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL--------GGL 153 Query: 193 LLAGGWRIPFIAS-----IALVAVGLWVRKSIPETPDFKELDKADDKPQVSPLKLLFRND 247 + PF A+ + + + +S + + ++PL Sbjct: 154 MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGE------RRPLRREALNPLASFRWAR 207 Query: 248 -LKGLAVVFFVAVGYNALSYIFKTFSLAYLTQFKGVEAHVTSLSVTLASLV-AIFAVPFF 305 + +A + V + + + + +A +S+ ++ ++ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 306 GWLCDKWSSKTVLMLGGLLSALFAFPFLQLLSTGEPMMIYLAIAVGTGILAPMMFAPQGS 365 G + + + LML G+++ + L + G + + GI P A Q Sbjct: 268 GPVAARLGERRALML-GMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMP---ALQA- 322 Query: 366 FLSRQFPTQTRSSGFGTGREVG-TAVAGGLAPLGGLALVAGSATHSTDGVALILAVAGVL 424 LSRQ G G T++ + PL A+ A S T + +G A I A L Sbjct: 323 MLSRQ--VDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASIT-TWNGWAWIAGAALYL 379 Query: 425 VVMFALLDQGW 435 + + AL W Sbjct: 380 LCLPALRRGLW 390
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.5 bits (66), Expect = 0.019 Identities = 10/50 (20%), Positives = 14/50 (28%) Query: 382 MALYQAGDFEGAAAAFAQAGTAAAHYNRGNALARAGELEAALDAYEQALE 431 M Y + A ++ L + GEL A A E Sbjct: 83 MGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQE 132
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 43.1 bits (101), Expect = 6e-06 Identities = 77/414 (18%), Positives = 145/414 (35%), Gaps = 29/414 (7%) Query: 644 NTRLVELRTQLGVVNAQLKDYQQQQQQLGEQLQPLLEQVQAHALWPALAPQDDSARGKWL 703 N L + L N LKD+ + + + L + A Q+ AR L Sbjct: 66 NNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADL 125 Query: 704 DGQLRRLGDEIDRDEKRQGALLALQKDAARLTQQLQVAGDAQQQAQRHLDQQHQALAADE 763 + L + D + L A + A L+ A + + + L A++ Sbjct: 126 EKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEK 185 Query: 764 QQLAQALESLESVLPP------------DILQALREDPANAFLGLDQQIAQRRQQLDLRK 811 L LE L L+A + A L++ + Sbjct: 186 AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADS 245 Query: 812 DELEEQQARKVQLDKQRDQQQARLHIQQQLQQKLAALDEQHR----QAQATLGELLGDQP 867 +++ +A K L+ ++ + + L +A + +A +L Sbjct: 246 AKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQ 305 Query: 868 SAEAWQQHMDTQLEQARAAEADSARQLQALHTQGVQLAGELKANQQRQQALEQEHQQLQG 927 A +Q + L+ +R A+ + Q +L + K ++ +Q+L ++ + Sbjct: 306 VLNANRQSLRRDLDASREAKKQLEAEHQ-------KLEEQNKISEASRQSLRRDLDASRE 358 Query: 928 EIAQWRSEHPELDDAGLDRLLAIDDSQVGELRQRLQAAEKAVEQGRVLLGEREQRLQQ-H 986 Q +EH L+ I ++ LR+ L A+ +A +Q L E +L Sbjct: 359 AKKQLEAEH-----QKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALE 413 Query: 987 TAQAHGELSVEALETALAELAVQLSAQEQQCAELRAQQAEDQRRQQASQALAEQ 1040 E S + E AEL +L A+ + E A+QAE+ + +A +A Q Sbjct: 414 KLNKELEESKKLTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQ 467 Score = 38.1 bits (88), Expect = 2e-04 Identities = 52/300 (17%), Positives = 110/300 (36%), Gaps = 12/300 (4%) Query: 630 QAEEAAAQQQVEQLNTRLVELRTQLGVVNAQLKDYQQQQQQLGEQLQPLLEQVQAHALWP 689 +A AA + +E+ + T L+ + + +L+ LE + Sbjct: 150 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 209 Query: 690 ALAPQDDSARGKWLDGQLRRLGDEIDRDEKRQGALLALQKDAARLTQQLQVAGDAQQQAQ 749 + + A L + L ++ A A K L+ ++A Sbjct: 210 SAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL 269 Query: 750 RHLDQQHQALAADEQQLAQALESLESVLPPDILQALREDPANAFLGLDQQIAQRRQQLDL 809 A +A + L +LE+ L L+ R+ LD Sbjct: 270 EGAMNFSTADSAKIKTLEAEKAALEAEK-----ADLEHQSQV----LNANRQSLRRDLDA 320 Query: 810 RKDELEEQQARKVQLDKQRDQQQARLHIQQQLQQKLAALDEQHRQAQATLGELLGDQPSA 869 ++ ++ +A +L++Q +A Q L++ L A E +Q +A +L + Sbjct: 321 SREAKKQLEAEHQKLEEQNKISEASR---QSLRRDLDASREAKKQLEAEHQKLEEQNKIS 377 Query: 870 EAWQQHMDTQLEQARAAEADSARQLQALHTQGVQLAGELKANQQRQQALEQEHQQLQGEI 929 EA +Q + L+ +R A+ + L+ +++ L K ++ ++ E+E +LQ ++ Sbjct: 378 EASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKL 437 Score = 37.0 bits (85), Expect = 5e-04 Identities = 63/326 (19%), Positives = 120/326 (36%), Gaps = 35/326 (10%) Query: 177 LKADDRERSELLEKLTNTAIYTRLGQRAFSKARETGEVHNDLKKQAEHLLPMEAEARAAL 236 L+ +D+ SE K+ ++A A + K E A +A L Sbjct: 101 LRKNDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL 160 Query: 237 DQALEQAQQQFKAEQARQRQLEQQRTWFAEHQRLQAQHGEAGTALQNAEHEWQQLAEQRV 296 ++ALE A A+ A+ + LE AE L+A+ E AL+ A + + + Sbjct: 161 EKALEGAMNFSTADSAKIKTLE------AEKAALEARQAELEKALEGAMNFSTADSAKIK 214 Query: 297 DLQRLERLAPQRHQ---------FHRQQHLAAQLAPVLADIDLQQRQQTEL----QQHTD 343 L+ + R + +A++ + A+ + +Q EL + + Sbjct: 215 TLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMN 274 Query: 344 ALQQALETARQHLVEHQALHGENAPRLRQAFAAQGDLARLDKELAEQREACTRVEQEVGA 403 + E AL E A Q+ + L ++L REA ++E E Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQK 334 Query: 404 AQQQLQQLEDSQQR-------SLQQLALIDSALAESEALGSLADAWQAYLPQLKQVMLIG 456 ++Q + E S+Q S + +++ + E +++A + L + Sbjct: 335 LEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR-------- 386 Query: 457 GRLAKGREELPGLQAQASQANAQLQA 482 L RE ++ +AN++L A Sbjct: 387 -DLDASREAKKQVEKALEEANSKLAA 411
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 27.8 bits (62), Expect = 0.043 Identities = 20/70 (28%), Positives = 27/70 (38%), Gaps = 14/70 (20%) Query: 13 QWAKIGNVPGLRCDPPKIPQDRGISSCLILAHGAGAPMDSRFMEDMAQRLAGQGVGVVRF 72 +WAK+ P D + LA G P D D G+G+G+ R Sbjct: 253 EWAKLVGEPSTTKDGAHVE----------LAANIGTPKDV----DGVLANGGEGIGLYRT 298 Query: 73 EFPYMAERRL 82 EF YM +L Sbjct: 299 EFLYMDRDQL 308
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.5 bits (61), Expect = 0.049 Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 7/52 (13%) Query: 169 LM--LAFGVGTWPVLLATGLAAERVGALLRKRGVRVAGGLLV-ILFGLWTLP 217 LM LAF +G P+ ++ G + G+ V GG++ L ++ +P Sbjct: 975 LMTSLAFILGVLPLAISNGAGSG----AQNAVGIGVMGGMVSATLLAIFFVP 1022
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 51.5 bits (123), Expect = 3e-09 Identities = 28/131 (21%), Positives = 47/131 (35%), Gaps = 5/131 (3%) Query: 382 DPAQPVAAAAVAVAPPAAASPVAEAVASVPVAEPPEQPEPPVVEVPVVAEVVEAPQSEPE 441 PAQP++ V A +AV P +PEP + P V + +P+ Sbjct: 40 APAQPISVTMVT----PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 95 Query: 442 PEPQPQPVEEVIDLPWEE-PVAAPAPVAPGQPPEPAPAVEAANPQPDYDEPPFDPSAYSP 500 P+P+P+PV++V + P + P +P + PA + S Sbjct: 96 PKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRA 155 Query: 501 AGMERDDEPPA 511 + P Sbjct: 156 LSRNQPQYPAR 166 Score = 32.3 bits (73), Expect = 0.004 Identities = 25/151 (16%), Positives = 38/151 (25%), Gaps = 5/151 (3%) Query: 401 SPVAEAVASVPVAEPPEQPEPPVVEVPVVAEVVEAPQSEPEPEPQPQPVEEVIDLPWEEP 460 V + V + E P P P+ +V P P+ QP E + P EP Sbjct: 21 GAVVAGLLYTSVHQVIELPAP---AQPISVTMV-TPADLEPPQA-VQPPPEPVVEPEPEP 75 Query: 461 VAAPAPVAPGQPPEPAPAVEAANPQPDYDEPPFDPSAYSPAGMERDDEPPADEDYYTPDS 520 P P P + + P R P + S Sbjct: 76 EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTS 135 Query: 521 DPAGFSYLDELAEHVQEEAPVQAPEPLPAAM 551 A + + + +P A Sbjct: 136 STATAATSKPVTSVASGPRALSRNQPQYPAR 166
>PF05860#haemagglutination activity domain. Length = 117 Score = 91.4 bits (227), Expect = 2e-23 Identities = 28/135 (20%), Positives = 53/135 (39%), Gaps = 23/135 (17%) Query: 29 AQLTVDAAANANTSIKQAGNGVPIVNIATPNGSGLSTNTFRDYNVGSNGLILNNATSKTQ 88 AQ+T D N++I I+ T GS L + F++++V ++G N + Sbjct: 1 AQITPDTTLPINSNIT-TEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPT--- 55 Query: 89 STQLGGIIIGNPNLRGQAAQVILNQVTGGNRSTLQGYTEVAGQAARVIVANPHGITCKGC 148 Q I+++VTGG+ S + G A + + NP+GI Sbjct: 56 -----------------NIQNIISRVTGGSVSNIDGLIRANATA-NLFLINPNGIIFGQN 97 Query: 149 GFINTPRATLTTGKP 163 ++ + + + Sbjct: 98 ARLDIGGSFVGSTAN 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 137 bits (347), Expect = 3e-38 Identities = 77/431 (17%), Positives = 163/431 (37%), Gaps = 56/431 (12%) Query: 22 RPVS--FTVMTVVALLLALMVVSFFFYGSYTRRSTVPGQLVPSSGQLKIHSSQYGVVLER 79 PVS ++ + ++ G +T G+L S +I + +V E Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 80 YVEEGQQVEQGGRLFLISSERS-VDSGPVQAEVSDQLQGQRR------------------ 120 V+EG+ V +G L +++ + D+ Q+ + Q R Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 121 --------SLEEELRKQQQLQVEARQSLDSKLRSLTQELDTLAQQIASQQRLVQLAGNAA 172 EEE+ + L E + ++ LD + + + N + Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 173 E-------RYQGLMDKGYISMDQLQQRQAELLGQRQSLQGLVRESTVLRQQLVERQHERA 225 + L+ K I+ + +++ + + L+ + + +++ + E Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 226 GLEALHGN----QLASIRRSLSSVQQALIESEAKRS-LVITAPQPGVATAILV-GPGQVV 279 + L N +L ++ + L ++E ++ VI AP + V G VV Sbjct: 291 LVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVV 350 Query: 280 DSSRALMSLVPADANLQAELYAPSKAIGFIQAGDAVLLRYQAYPYQKFGQHHGQVISVSR 339 ++ LM +VP D L+ +K IGFI G +++ +A+PY ++G G+V +++ Sbjct: 351 TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Query: 340 TTLSAAELANVVGSVPGLGGNGEQIYRIRVAIDRQSVQAYGESRALQAGMLVEADVLQET 399 + L V + + ++I+ + ++ L +GM V A++ Sbjct: 411 DAIEDQRLGLV--------------FNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456 Query: 400 RRLYEWVLEPL 410 R + ++L PL Sbjct: 457 RSVISYLLSPL 467
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 53.4 bits (128), Expect = 1e-11 Identities = 28/113 (24%), Positives = 50/113 (44%), Gaps = 6/113 (5%) Query: 16 LNDKATMLGHAAMVMAGCRRSSGFQIRTLYYWLAPAIEHAQIIMLFDSTCAPRGFLIWAH 75 +N +LGH + + A + + + PAI+ Q ++L P + WA+ Sbjct: 3 INKPLEILGHVSWLWASSPLHRNWPVSLFAINVLPAIQANQYVLLTRDD-YPVAYCSWAN 61 Query: 76 LAPDTEQRLLQDPNFLLHPSEWNEGGRAWVIDFCFPGGAVKEALSMLRQHLRE 128 L+ + E + L D L+ +W G R W ID+ P G L +++R+ Sbjct: 62 LSLENEIKYLNDVTSLV-AEDWTSGDRKWFIDWIAPFGDN----GALYKYMRK 109
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 72.3 bits (177), Expect = 7e-19 Identities = 43/108 (39%), Positives = 55/108 (50%), Gaps = 3/108 (2%) Query: 1 MSSELQVIDLQEGDGKAVVKGALITTQYRGTLADGSEFDSSWSRGKPFQCVIGTGRVIKG 60 + S LQ + G G K +T +Y GTL DG+ FDS+ GKP +VI G Sbjct: 124 LPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKP--ATFQVSQVIPG 181 Query: 61 WDQGLMGMRVGGKRKLLVPAHLGYGERPVGS-IPPNSDLTFEIELLEV 107 W + L M G ++ VPA L YG R VG I PN L F+I L+ V Sbjct: 182 WTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>PERTACTIN#Pertactin signature. Length = 922 Score = 34.3 bits (78), Expect = 9e-06 Identities = 18/45 (40%), Positives = 21/45 (46%) Query: 13 PNPNPNPNPNPNPNPNPPPILQLPKTTARSPPCPRKTKAPAYAKP 57 P P P P P P P P PP Q P+ P R+ +APA P Sbjct: 569 PAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Score = 31.6 bits (71), Expect = 7e-05 Identities = 16/41 (39%), Positives = 17/41 (41%) Query: 6 PKQSSPNPNPNPNPNPNPNPNPNPPPILQLPKTTARSPPCP 46 P P P P P P P P P PP Q P+ R P P Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAP 608 Score = 26.2 bits (57), Expect = 0.006 Identities = 18/53 (33%), Positives = 23/53 (43%), Gaps = 5/53 (9%) Query: 8 QSSPNPNPNPNPNPN-----PNPNPNPPPILQLPKTTARSPPCPRKTKAPAYA 55 + +P P P P P P P P P P + P+ A PP R+ A A A Sbjct: 572 KPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAAANA 624
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 320 bits (822), Expect = e-110 Identities = 101/349 (28%), Positives = 187/349 (53%), Gaps = 3/349 (0%) Query: 9 DKTEEPTEKRKRDSREKGEVARSKELNTVAVTLAGAGGLLAFGGYLAETLMTLMRMNFSL 68 +KTE+PT K+ RD+R+KG+VA+SKE+ + A+ +A + L+ Y E LM + Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQ 63 Query: 69 TREVIVDERSMGAFLLASGKMAIWSVQPILILLFVISFVAPIALGGFLFSGSLLQPKFSR 128 + + +++ + + P+L + +++ + + GFL SG ++P + Sbjct: 64 SY--LPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKK 121 Query: 129 MNPLSGIKRMFSMNALTELLKAMAKFIMILLVALLVLASDREALLAIANEPLEQAIIHAV 188 +NP+ G KR+FS+ +L E LK++ K +++ ++ +++ + LL + +E Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 189 QVVGWSALWMAAGLLLIAGLDVPYQLFQTNKKMKMTKQEVKDEYKDSEGKPEVKQRIRQL 248 Q++ + G ++I+ D ++ +Q K++KM+K E+K EYK+ EG PE+K + RQ Sbjct: 182 QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQF 241 Query: 249 QREMSQRRMMAAVPDADVIITNPTHYAVALQYNPDKGGTAPLLVAKGTDFIALKIREIGV 308 +E+ R M V + V++ NPTH A+ + Y + PL+ K TD +R+I Sbjct: 242 HQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETP-LPLVTFKYTDAQVQTVRKIAE 300 Query: 309 EHNVQILESPALARAIYYSTEMEQEIPAGLYLAVAQVLAYVFQIRQYRA 357 E V IL+ LARA+Y+ ++ IPA A A+VL ++ + + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQ 349
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 135 bits (342), Expect = 5e-41 Identities = 95/255 (37%), Positives = 151/255 (59%), Gaps = 2/255 (0%) Query: 1 MLELTDTQIGTWVATFILPLFRVMAVLMTMPIFGTKMLPARVRLYAAVAITVVIVPGLPP 60 ML++T Q +W+ + PL RV+A++ T PI + +P RV+L A+ IT I P LP Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 LPEIDPLSVRGVLLCAEQVIVGALFGFSLQLLFQAFVIAGQIVAVQMGMAFASMVDPANG 120 S + L +Q+++G GF++Q F A AG+I+ +QMG++FA+ VDPA+ Sbjct: 61 NDVPV-FSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 VNVAVISQFMTMLVSVLFLLMNGHLVVFEVLTESFTTLPVGSALVVNHFWE-IAGRLSWV 179 +N+ V+++ M ML +LFL NGHL + +L ++F TLP+G + ++ + + S + Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 180 LGAALLLILPAIAALLVVNIAFGVMTRAAPQLNIFSIGFPLTLVLGMGIFWVGLADILPH 239 L+L LP I LL +N+A G++ R APQL+IF IGFPLTL +G+ + + I P Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPF 239 Query: 240 YQALASEALQWLREL 254 + L SE L ++ Sbjct: 240 CEHLFSEIFNLLADI 254
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 51.7 bits (124), Expect = 1e-12 Identities = 22/70 (31%), Positives = 37/70 (52%) Query: 7 VDLFRDALWLTTLMVAVLVVPSLLIGLVVAMFQAATQINEQTLSFLPRLLVMLITLIVAG 66 V AL+L ++ + + +IGL+V +FQ TQ+ EQTL F +LL + + L + Sbjct: 5 VFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLS 64 Query: 67 PWLVQKFMEY 76 W + + Y Sbjct: 65 GWYGEVLLSY 74
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 269 bits (688), Expect = 2e-93 Identities = 137/243 (56%), Positives = 180/243 (74%), Gaps = 2/243 (0%) Query: 6 RFLLTLALLLAAPLALAADPLSIPAITLSSGADGQQEYSVSLQILLIMTALSFIPAFVIL 65 R L +LL LA +P IT G Q +S+ +Q L+ +T+L+FIPA +++ Sbjct: 3 RLLSVAPVLLWLITPLAFA--QLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 66 MTSFTRIIIVFSILRQALGLQQTPSNQVLTGMALFLTMFIMAPVFDRVNKDALQPYLAEQ 125 MTSFTRIIIVF +LR ALG P NQVL G+ALFLT FIM+PV D++ DA QP+ E+ Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 126 VTAQQAIDKAQGPLKDFMLAQTRQSDLDLFMRLSKRTDIAGPDQVPLTILVPAFVTSELK 185 ++ Q+A++K PL++FML QTR++DL LF RL+ + GP+ VP+ IL+PA+VTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 186 TAFQIGFMIFIPFLIIDMVVASVLMAMGMMMLSPLIISLPFKIMLFVLVDGWALIMGTLA 245 TAFQIGF IFIPFLIID+V+ASVLMA+GMMM+ P I+LPFK+MLFVLVDGW L++G+LA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 246 GSF 248 SF Sbjct: 241 QSF 243
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 475 bits (1225), Expect = e-168 Identities = 178/480 (37%), Positives = 257/480 (53%), Gaps = 32/480 (6%) Query: 4 KVLLVEDDRVLRQALADTLEIGGFCLRAVGSAEEALLAVTEESFSLVVSDVNMPGMDGHQ 63 +L+ +DD +R L L G+ +R +A + LVV+DV MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LLAQLRRNHPQLPVLLMTAHAAVERAVEAMRQGAVDYLVKPFEP--------KALISLVA 115 LL ++++ P LPVL+M+A A++A +GA DYL KPF+ +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 116 RHAVGAGASAGEEGPVACEPASRQLLELAARVAQSDSTVLISGESGTGKEVLARYIHQQS 175 R + S V A +++ + AR+ Q+D T++I+GESGTGKE++AR +H Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYG 184 Query: 176 RRVDQPFVAINCAAIPDNMLEATLFGHEKGAFTGAIAAQAGKFEQADGGTLLLDEISEMP 235 +R + PFVAIN AAIP +++E+ LFGHEKGAFTGA G+FEQA+GGTL LDEI +MP Sbjct: 185 KRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMP 244 Query: 236 LGLQAKLLRVLQEREVERVGGRKPIALDIRILATTNRDLAGEVAAGRFREDLYYRLSVFP 295 + Q +LLRVLQ+ E VGGR PI D+RI+A TN+DL + G FREDLYYRL+V P Sbjct: 245 MDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVP 304 Query: 296 MAWRALRERPADIVPLAERLLARHAQKMRHAQVRLSAEARACLQAYAWPGNVRELDNAIQ 355 + LR+R DI L + + A+K R EA ++A+ WPGNVREL+N ++ Sbjct: 305 LRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVR 363 Query: 356 RALILQQGGVIEAADFCL-----------------AGAIPLSVP---KMATIEPLSVEPA 395 R L VI +G++ +S M + Sbjct: 364 RLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDAL 423 Query: 396 AEVGGLGDDMRRHEFQMIIDTLRAERGRRKEAAERLGISPRTLRYKLAQMRDAGLDVEAS 455 G + E+ +I+ L A RG + +AA+ LG++ TLR K +R+ G+ V S Sbjct: 424 PPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGVSVYRS 480
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 1e-05 Identities = 19/99 (19%), Positives = 38/99 (38%), Gaps = 20/99 (20%) Query: 304 LIENA----LQASHEPARIKVHLSRRDDSLRICVSDAGSGIDAQLLTRLGEPFLTTKATG 359 L+EN + + +I + ++ + ++ + V + GS L Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL------------ALKNTKES 310 Query: 360 TGLGLAVVQAVVRAHRG---TLGLRSKPGRGTCVTVVLP 395 TG GL V+ ++ G + L K G+ V++P Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 506 bits (1304), Expect = e-179 Identities = 179/488 (36%), Positives = 255/488 (52%), Gaps = 10/488 (2%) Query: 5 TKILLIDDDSERRRDLAVVLNFLGEDNLSCSSGDWQQVVEGLSSSREVLCVLIGTVNAPA 64 IL+ DDD+ R L L+ G D S+ + +++ + V+ V Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNA--ATLWRWIAAG-DGDLVVTDVVMPDE 60 Query: 65 SVLGLLKTVVGWDEFLPVLLLGEISSAE-FPEDLRRRVLSNLEMPPSYSQLLDSLHRAQV 123 + LL + LPVL++ ++ + + L P ++L+ + RA Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 124 YREMYDQARERGRQREPNLFRSLVGTSRAIQHVRQMMQQVADTDASVLILGESGTGKEVV 183 + R + + LVG S A+Q + +++ ++ TD +++I GESGTGKE+V Sbjct: 121 EP----KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176 Query: 184 ARNLHYHSKRREAPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGGTLF 243 AR LH + KRR PFV +N AIP +L+ESELFGHEKGAFTGA T GRFE A GGTLF Sbjct: 177 ARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLF 236 Query: 244 LDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQSIDVRIIAATHKNLETMIEDGTFREDL 303 LDEIGDMP+ Q +LLRVLQ+ + VG DVRI+AAT+K+L+ I G FREDL Sbjct: 237 LDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDL 296 Query: 304 YYRLNVFPIEMAPLRERVEDIPLLMNELISRMEHEKRGSIRFNSASIMSLCRHGWPGNVR 363 YYRLNV P+ + PLR+R EDIP L+ + + E E RF+ ++ + H WPGNVR Sbjct: 297 YYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 364 ELANLVERMAIMHPYGVIGVAELPKKFRY-VDDEDEQLVDSLRSDLEERVAINGHAPN-F 421 EL NLV R+ ++P VI + + R + D + + L A+ + F Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 422 ASHAMLPPEGLDLKDYLGSLEQGLIQQALDDANGIVARAAERLRIRRTTLVEKMRKYGMS 481 AS P L +E LI AL G +AA+ L + R TL +K+R+ G+S Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476 Query: 482 RQGGEEQA 489 A Sbjct: 477 VYRSSRSA 484
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 26.0 bits (57), Expect = 0.038 Identities = 11/56 (19%), Positives = 22/56 (39%) Query: 59 QSSQRKLDFSIDDSTGRVVVKVIATESGDVIRQLPSETALKLAQSLSEAGSLLFDG 114 + R ++I+ G + VK T+ ++ + L + Q L +L G Sbjct: 492 TTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSG 547
>FLAGELLIN#Flagellin signature. Length = 507 Score = 182 bits (463), Expect = 5e-54 Identities = 162/508 (31%), Positives = 233/508 (45%), Gaps = 40/508 (7%) Query: 2 ALTVNTNIASVTTQVNLNKASSAQTTSMQRLSSGLRINSAKDDAAGLQIANRLTSQINGL 61 A +NTN S+ TQ NLNK+ S+ +++++RLSSGLRINSAKDDAAG IANR TS I GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 GQAVKNANDGISIAQTAEGAMQASTDILQKMRTLALSSATGSLSADDRKSNNDEYQALTA 121 QA +NANDGISIAQT EGA+ + LQ++R L++ + G+ S D KS DE Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELNRISETTTFGGQKLLDGSYGTKAIQVGANANETINLTLENVAASNIGSQQVKSTAIAP 181 E++R+S T F G K+L IQVGAN ETI + L+ + ++G Sbjct: 121 EIDRVSNQTQFNGVKVLSQD-NQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 SAGGVAAGSLSVT-----------------GNGQTATVAYAAGASAKQIASNLNGSIGGL 224 + G S +G T A K + NG + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 225 TATASTEVKLDVTAATPSN------FKLSVGSSGTVDFVGVTDQKGLADQLKSNAAKLGI 278 A +T V L T + + ++ D D N + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 279 SVNYDEAKQTLSIKSDTGENINFSAADANAQTNI----------------SIAAKDGSGN 322 S + K TL++ T N AA + N+ + +AK Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLE 359 Query: 323 FAAGAALGGAAIVVTGQISLDSAKGFSLGGATDLFGAATVTSAKTTISQTDVTDATKAQN 382 V + + ++A +F T + T I++ N Sbjct: 360 ANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTAN 419 Query: 383 ALAVIDKAIGSIDSVRSGLGATQNRLTTTVDNLQNIQKNSTAARSTVQDVDFASETAELT 442 LA ID A+ +D+VRS LGA QNR + + NL N N +ARS ++D D+A+E + ++ Sbjct: 420 PLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMS 479 Query: 443 KQQTLQQASTAILSQANQLPSSVLKLLQ 470 K Q LQQA T++L+QANQ+P +VL LL+ Sbjct: 480 KAQILQQAGTSVLAQANQVPQNVLSLLR 507
>FLAGELLIN#Flagellin signature. Length = 507 Score = 53.1 bits (127), Expect = 2e-09 Identities = 76/499 (15%), Positives = 146/499 (29%), Gaps = 17/499 (3%) Query: 17 TKNFADLMKSKTQIDSGVRIQTAADDPVGAARLLLLQQQQALLKQYDGNMTTVNNSLLQE 76 K+ + L + ++ SG+RI +A DD G A L Q N + Sbjct: 18 NKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTT 77 Query: 77 ESVLSTINDAMQRASELALRAGGAGVTDADRLSISSELKEIEANIFGLLNSRDANGDYMF 136 E L+ IN+ +QR EL+++A +D+D SI E+++ I + N NG + Sbjct: 78 EGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSNQTQFNGVKVL 137 Query: 137 GGTKTSSPPYVRNADGTYSYQGDQTQLSLQVSDTLSLATNDTGFSIFDSAKNKSRTQSTL 196 N T + + + ++ D + Sbjct: 138 SQDNQMKIQVGANDGETITIDLQKID-VKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYD 196 Query: 197 VTPPVDDGKVALSPGLLTSNNTYNSSFTAGQPYKITFTSATQYTVTDALGNDITAETPTN 256 + +T + T + D+ T Sbjct: 197 TYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAENNTAVDLFKTT--- 253 Query: 257 GTFDSKAEGGNRIALRGVEFEITASLKEGDDANAVFAGREFSVQARPDTLTTVRGAGNPS 316 S A A+ G + TT+ G Sbjct: 254 ---KSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTTINGEKVTL 310 Query: 317 SAQVTSGAVTDPAAYSSTFPSDGAVIKFTGANTYEFYAQPLTADSKPVASGTFTAPSLTV 376 + + + A + + G T++ + +A + + Sbjct: 311 TVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLEANN-------- 362 Query: 377 AGVTYQVSGTPQTGDQFAVNANNHQNQSVLETISQLRAALDAPPGTSGDNTAIKNAVASA 436 V + T + A A + + A+ + A K+ A+ Sbjct: 363 -AVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKST-ANP 420 Query: 437 VANLASAREQVDITRGSIGARGNSLDIQRQENTSLSTANKVTQDAIGNTDMADASIMLTL 496 +A++ SA +VD R S+GA N D + T + I + D A ++ Sbjct: 421 LASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMSK 480 Query: 497 QQAMLEASQLAFSRISQLS 515 Q + +A ++ +Q+ Sbjct: 481 AQILQQAGTSVLAQANQVP 499
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 235 bits (600), Expect = 3e-71 Identities = 148/448 (33%), Positives = 245/448 (54%), Gaps = 24/448 (5%) Query: 2 SLISIGLSGLNASQTALSITGNNIANAAVSGYSRQQTIQTTGPSHNIGTGFVGTGTTLSD 61 SLI+ +SGLNA+Q AL+ NNI++ V+GY+RQ TI S G+VG G +S Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 62 VRRIYNAYLDNQLQTSTSLNTDAAAFQDQITGIDKLLAESDTGISSVLTAFFSALQTASA 121 V+R Y+A++ NQL+ + + ++ A +Q++ ID +L+ S + +++ + FF++LQT + Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 122 KPSDVASRQLLLTQAQTLSNRFNAISSQMSKQNDSINSQLDTLSGQVNKLTSSIADLNKQ 181 D A+RQ L+ +++ L N+F + Q+ +N + Q+N IA LN Q Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 182 ITQLSA--SGASPNNLLDARSEAVRQLNELVGVTVQER-DGNYDVYLGNGQSLVTGNRAN 238 I++L+ +GASPNNLLD R + V +LN++VGV V + G Y++ + NG SLV G+ A Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 239 TLSAVPSAADQSQYSLQINYPTFSSDVT--SVVTGGQIGGLLRYRNDVLTPSMNELGRVA 296 L+AVPS+AD S+ ++ T + ++ G +GG+L +R+ L + N LG++A Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 297 LVVADSINSQLGQGLDANAQFGSALFSSINSALAISQRSLASANNSAGSGNLDVTIANSG 356 L A++ N+Q G DAN G F+ I + ++ + G + T+ ++ Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFA-------IGKPAVLQNTKNKGDVAIGATVTDAS 354 Query: 357 ALTTYDYEVKFTGPNQYSVRRSDGTDMGNFDLTTTPPPVIDGF----TLKLN-GGGLAAG 411 A+ DY++ F NQ+ V R + T T P +G L+L G A Sbjct: 355 AVLATDYKISFDN-NQWQVTRLAS------NTTFTVTPDANGKVAFDGLELTFTGTPAVN 407 Query: 412 DSFKVSPTRSAAGSINTVLTDANKLAFA 439 DSF + P A +++ ++TD K+A A Sbjct: 408 DSFTLKPVSDAIVNMDVLITDEAKIAMA 435 Score = 77.7 bits (191), Expect = 4e-17 Identities = 47/111 (42%), Positives = 60/111 (54%), Gaps = 3/111 (2%) Query: 567 FNADGKSDNRNAQALLGLQTKSTVGVNSGGGSSFTSAYASLVERVGAKANQAKIDTVATK 626 G SDNRN QALL LQ+ S GG SF AYASLV +G K K + Sbjct: 437 EEDAGDSDNRNGQALLDLQSNSKT---VGGAKSFNDAYASLVSDIGNKTATLKTSSATQG 493 Query: 627 AVLDAAKESRNGVSGVNLDDEAANLIKFQHYYTASSQIIKAAQETFSILIN 677 V+ + +SGVNLD+E NL +FQ YY A++Q+++ A F LIN Sbjct: 494 NVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 144 bits (364), Expect = 3e-42 Identities = 70/175 (40%), Positives = 103/175 (58%), Gaps = 1/175 (0%) Query: 224 AQPPLAPSKAFSDSDAFVATMLPMAEQAAKRIGIDPRYLVAQAALETGWGKSVMRNPDGS 283 A P DS AF+A + A+ A+++ G+ ++AQAALE+GWG+ +R +G Sbjct: 136 AVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGE 195 Query: 284 SSHNLFGIKATGNWQGGEARAITSEFRGGQFVKETAAFRSYDSYQDSFHDLVSLLQNNNR 343 S+NLFG+KA+GNW+G T+E+ G+ K A FR Y SY ++ D V LL N R Sbjct: 196 PSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPR 255 Query: 344 YKDAVGAADNPEQFARELQKAGYATDPDYARKIISIARQLRPTQEYAMAGTNTNL 398 Y AV A + EQ A+ LQ AGYATDP YARK+ ++ +Q++ + + N+ Sbjct: 256 YA-AVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDKVSKTYSMNI 309 Score = 67.0 bits (163), Expect = 2e-14 Identities = 53/172 (30%), Positives = 84/172 (48%), Gaps = 17/172 (9%) Query: 4 KSLISGASDSGAFTDLNRLSSLKAGDRDSEGNIRKVAQEFESLFVSEMLKASRKATDVMA 63 K L S A D+ + +L KAG+ D NIR VA++ E +FV MLK+ R A Sbjct: 6 KLLASAAWDAQSLNELKA----KAGE-DPAANIRPVARQVEGMFVQMMLKSMRDAL---- 56 Query: 64 DEDSPMNSDTVKQYRDMYDQQLAVSMSRQGGGIGLQDVLVRQLSK-QKHSVNSSPFPRTD 122 +D +S+ + Y MYDQQ+A M+ G G+GL +++V+Q++ Q S+P Sbjct: 57 PKDGLFSSEHTRLYTSMYDQQIAQQMT-AGKGLGLAEMMVKQMTPEQPLPEESTPAAPMK 115 Query: 123 GAAPVLWGSRVAAPVHGEQPAAGRNDVAAL--NSR----RLALPGKLTDRLL 168 + + A Q A RN +L +S+ +L+LP +L + Sbjct: 116 FPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQS 167
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 450 bits (1158), Expect = e-161 Identities = 165/366 (45%), Positives = 224/366 (61%), Gaps = 10/366 (2%) Query: 7 LIAATLLLSCAFGAHAERLKDIASISGVRANQLIGYGLVVGLNGTGDQTTQTPFTLQTFN 66 A L + A R+KDIAS+ R NQLIGYGLVVGL GTGD +PFT Q+ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 67 NMLSQFGIKVPPGSGNVQLKNVAAVSVHADLPAFAKPGQVIDITVSSIGNSKSLRGGSLL 126 ML GI G N KN+AAV V A+LP FA PG +D+TVSS+G++ SLRGG+L+ Sbjct: 73 AMLQNLGITTQGGQSNA--KNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLI 130 Query: 127 MTPLKGIDGNVYAIAQGNLVVGGFDAEGRDGSKITVNVPSAGRIPGGASVERAVPSGFNQ 186 MT L G DG +YA+AQG L+V GF A+G D + +T V ++ R+P GA +ER +PS F Sbjct: 131 MTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKD 189 Query: 187 GNSLTLNLNRPDFTTAKRIVDKVNEL----LGPGVAQAVDGGSVRVTAPMDPSQRVDYLS 242 +L L L PDF+TA R+ D VN G +A+ D + V P + ++ Sbjct: 190 SVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPR-VADLTRLMA 248 Query: 243 ILENLEIDPGQAVAKVIINSRTGTIVIGQNVKVSPAAVTHGSLTVTITEDPIVSQPGPFS 302 +ENL ++ AKV+IN RTGTIVIG +V++S AV++G+LTV +TE P V QP PFS Sbjct: 249 EIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFS 307 Query: 303 NGQTAVVPRSRVNAEQEAKPMFKFGPGTTLDEIVRAVNQVGAAPSDLMAILEALKQAGAL 362 GQTAV P++ + A QE + G L +V +N +G ++AIL+ +K AGAL Sbjct: 308 RGQTAVQPQTDIMAMQEGSKVA-IVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGAL 366 Query: 363 QADLIV 368 QA+L++ Sbjct: 367 QAELVL 372
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.2 bits (104), Expect = 3e-07 Identities = 11/47 (23%), Positives = 20/47 (42%) Query: 213 TTEQQTLEASNVSTVEELVNMITTQRAYEMNSKVISAADKMLSFVTQ 259 Q S V+ EE N+ Q+ Y N++V+ A+ + + Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 40.7 bits (95), Expect = 4e-06 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 14/79 (17%) Query: 5 LWVAKTGLSAQDTNLAVISNNLANVSTTGFKRDRAEFQDLLYQIKRQPGAQSTQDSELPS 64 + A +GL+A L SNN+++ + G+ R + +S L + Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQTT--------------IMAQANSTLGA 49 Query: 65 GLQVGTGVRIVGTQKSFNA 83 G VG GV + G Q+ ++A Sbjct: 50 GGWVGNGVYVSGVQREYDA 68
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.9 bits (106), Expect = 4e-07 Identities = 21/65 (32%), Positives = 26/65 (40%), Gaps = 5/65 (7%) Query: 2 SFNIGLSGLYAANKALNVTGNNIANVATTGFKSSRAEFGDQYSQSIRGTAGGKTQVGSGV 61 N +SGL AA ALN NNI++ G+ S T G VG+GV Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANS-----TLGAGGWVGNGV 57 Query: 62 KTMAV 66 V Sbjct: 58 YVSGV 62 Score = 38.8 bits (90), Expect = 4e-05 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 12/84 (14%) Query: 367 GATAWKESYASGVPIIGEPDTGTLGRIAGS-----------SLEDSNVDLTGELVNLIKA 415 GA ++ ++YAS V IG T TL + + S V+L E NL + Sbjct: 463 GAKSFNDAYASLVSDIGN-KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRF 521 Query: 416 QSNYQANAKTISTESTIMQTIIQM 439 Q Y ANA+ + T + I +I + Sbjct: 522 QQYYLANAQVLQTANAIFDALINI 545
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 34.9 bits (80), Expect = 6e-05 Identities = 8/38 (21%), Positives = 20/38 (52%) Query: 108 NVNVVEEMADMISASRAFQTNAELMNTAKNMMQKVLTL 145 VN+ EE ++ + + NA+++ TA + ++ + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 29.9 bits (67), Expect = 0.003 Identities = 19/77 (24%), Positives = 29/77 (37%), Gaps = 15/77 (19%) Query: 4 ASVFNIAGSGMSAQNTRLNTVASNIANAETVSSSIDQTYRARHPVFATTFQQAQGGAGQS 63 +S+ N A SG++A LNT ++NI++ + R G G Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYT-------RQTTIMAQANSTLGAGGW- 52 Query: 64 LFEDQGEAGQGVQVKGI 80 G GV V G+ Sbjct: 53 -------VGNGVYVSGV 62
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.8 bits (124), Expect = 2e-09 Identities = 22/123 (17%), Positives = 50/123 (40%), Gaps = 14/123 (11%) Query: 181 RVLTVDDSSVARKQVSRCLQTVGVEVVALNDGRQALDYLRKLVDEGKRPEEEFLMMISDI 240 +L DD + R +++ L G +V ++ ++ + ++++D+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDV 55 Query: 241 EMPEMDGYTLTAEIRS-DPRMQKLHICLHTSLSGVFNQAMVKKVGADDFLAK-FRPDDLA 298 MP+ + + L I+ P + L + + +A + GA D+L K F +L Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFM-TAIKAS--EKGAYDYLPKPFDLTELI 112 Query: 299 QRV 301 + Sbjct: 113 GII 115
>cloacin#Cloacin signature. Length = 551 Score = 30.8 bits (69), Expect = 0.028 Identities = 15/49 (30%), Positives = 28/49 (57%) Query: 269 VVEAKLNVLPIPKYAVLVNVRYTSFMDALRDANALMAHKPLSIETVDSK 317 + E+ ++ LP+ K V VNVR + R ++++ P+S+ VD+K Sbjct: 164 ITESPVSSLPLDKATVNVNVRVVDDVKDERQNISVVSGVPMSVPVVDAK 212
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 29.3 bits (65), Expect = 0.002 Identities = 11/45 (24%), Positives = 16/45 (35%) Query: 53 AAGFSGSLIVAEFDSLAAAQAWADADPYIAAGVYDKVVVKPFKQV 97 G GS+ E ++ A W +P A V V +V Sbjct: 278 VIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.002 Identities = 19/90 (21%), Positives = 33/90 (36%), Gaps = 8/90 (8%) Query: 27 LEAGARITELQQRLEESEKQRDALTLQLQNQDNERESAQLSRLRQDNQRLKLAIKELQAA 86 +EA + + +LE+ E + + + Q ++ L +LRQ + L EL Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 87 S--------SAPQRLLTDQQQWFLIGSVVA 108 AP + Q + G VV Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVT 351
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 100 bits (251), Expect = 8e-27 Identities = 38/116 (32%), Positives = 61/116 (52%) Query: 4 LLLIDDDQELCELLGSWLTQEGFAVRACHDGQSARQALATHAPAAVVLDVMLPDGSGLEL 63 +L+ DDD + +L L++ G+ VR + + + +A VV DV++PD + +L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LKQLRSEHTDLPVLMLSARGEPLDRILGLELGADDYLAKPCDPRELTARLRAVLRR 119 L +++ DLPVL++SA+ + I E GA DYL KP D EL + L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>NEISSPPORIN#Neisseria sp. porin signature. Length = 348 Score = 28.4 bits (63), Expect = 0.010 Identities = 13/20 (65%), Positives = 15/20 (75%), Gaps = 1/20 (5%) Query: 1 MRKTLIALMFAAALPTVAMA 20 M+K+LIAL AALP AMA Sbjct: 1 MKKSLIALTL-AALPVAAMA 19
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.004 Identities = 16/100 (16%), Positives = 33/100 (33%), Gaps = 17/100 (17%) Query: 359 VDNLLRNALRFNPAGQPIEVHARREQDRIVLSVRDHGPGVAAEHLAQLGEPFFRAPGQEA 418 V+N +++ + P G I + ++ + L V + G Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLAL---------------KNTK 308 Query: 419 PGHGLGLA-IARKAAERHGGSLVLG-NHPQGGFIATLELP 456 G GL + + +G + + QG A + +P Sbjct: 309 ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 110 bits (276), Expect = 5e-26 Identities = 66/200 (33%), Positives = 86/200 (43%), Gaps = 25/200 (12%) Query: 2081 DNHGGTATGAVDITYQAGNTLTGTSGDDVLLAGAGDTILHGGAGNDVLVAGAGNNSLYGG 2140 + G D + L GT+ D I HG G+D++ GN+ LYG Sbjct: 703 THINGKNLTETD-NLYSVEELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGD 761 Query: 2141 DGDDLLIGGPGNDLLDGGAGNDTASYARATSGVTVDLSHVGQQNTVGAGLDTLNGIENLI 2200 G+D L GG G+D L GG GND AG + LNG + Sbjct: 762 KGNDTLSGGNGDDQLYGGDGNDKLI--------------------GVAGNNYLNGGD--- 798 Query: 2201 GSDYNDTLTGNDGDNLLNGGAGNDVLRGGAGNDILIGGRGDDTLTGGSGNDTFVWQKGDT 2260 G D + N+L GG GND L G G D+L GG GDD L GG GND + + G Sbjct: 799 GDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGY- 857 Query: 2261 GHDTVTDFTPGSDRLDLSQL 2280 GH + D D+L L+ + Sbjct: 858 GHHIIDDDGGKEDKLSLADI 877 Score = 84.6 bits (209), Expect = 3e-18 Identities = 57/218 (26%), Positives = 83/218 (38%), Gaps = 27/218 (12%) Query: 2106 GDDVLLAGAGDTILHGGAGNDVLVAGAGNNSLYGGDGDDLLIGGP---------GNDLLD 2156 GDD + AG ++ G G+DV+ + DG G +L Sbjct: 619 GDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQ 678 Query: 2157 GGAGNDTASYARATSGV---TVDLSHVGQQNTVGAGLDTLNGIENLIG---------SDY 2204 S + T + + +H+ +N D L +E LIG S + Sbjct: 679 EVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTET--DNLYSVEELIGTTRADKFFGSKF 736 Query: 2205 NDTLTGNDGDNLLNGGAGNDVLRGGAGNDILIGGRGDDTLTGGSGNDTFVWQKGDTGHDT 2264 D G DGD+L+ G GND L G GND L GG GDD L GG GND + G G++ Sbjct: 737 TDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLI---GVAGNNY 793 Query: 2265 VTDFTPGSDRLDLSQLLQGENATSASLDDYLHFKVSGS 2302 + G D + +N + + G+ Sbjct: 794 LNG-GDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGA 830
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.3 bits (65), Expect = 0.001 Identities = 23/82 (28%), Positives = 30/82 (36%), Gaps = 8/82 (9%) Query: 15 STADAAGQQRPLTTVPGAPGTATPTPYPQITPSTPPKAGANRPGAPLLPPMPLPGP---- 70 +T D RP T PG+ P P+++P+ P P P P P P Sbjct: 303 TTVDVQVIPRPDLT-PGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNP 361 Query: 71 ---PKDQPLPGLSQDPPKPPDK 89 P PG D P PD+ Sbjct: 362 DANPDTDGQPGTRPDSPAVPDR 383
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 114 bits (286), Expect = 3e-33 Identities = 34/112 (30%), Positives = 51/112 (45%), Gaps = 12/112 (10%) Query: 65 YFEYDSSDLKPEAMRSLDVHA---KDLKANGNRVVLEGNTDERGTREYNMALGERRAKAV 121 F ++ + LKPE +LD +L VV+ G TD G+ YN L ERRA++V Sbjct: 222 LFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSV 281 Query: 122 QRYLVLQGVSPAQLELVSYGEERPVATGNDEQS---------WAQNRRVELR 164 YL+ +G+ ++ GE PV + A +RRVE+ Sbjct: 282 VDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 66.6 bits (162), Expect = 5e-14 Identities = 34/226 (15%), Positives = 77/226 (34%), Gaps = 7/226 (3%) Query: 37 TPELPPSKPIVQATLYQLKSKSQATTQTNQKIAGEAKKTASRQTEVEQMEQKKVEQEAVK 96 T P+ ++ A + A T S TE K+ + K Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVD-EAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 97 A---AEQKKADAAQKAEEAREAAEAK-KAEEAAKAAEQKKAAEAKKAEEAKKAAEKQQAD 152 A + A + A+EA+ +A + E A++ + K + + +E ++++A Sbjct: 1054 NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAK 1113 Query: 153 IAKKKAEEEAKKQAEEEAKKQAAEEAKKKAAEDAKKKAAEDAKKKAAAEEAKKKAAEEAK 212 + +K +E K ++ K++ +E + +A + + K+ + A E Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTN--TTADTEQP 1171 Query: 213 KKAAADAQKKKAQEAARKAAEDKKAQALAELLSDTTERQQALADEQ 258 K + ++ E+ + + TT+ Sbjct: 1172 AKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Score = 61.2 bits (148), Expect = 2e-12 Identities = 35/190 (18%), Positives = 61/190 (32%), Gaps = 14/190 (7%) Query: 69 AGEAKKTASRQTEVEQMEQKKVEQEAVKAAEQKKADAAQKAEEAREAAEAKKAEEAAKAA 128 + Q +V + E V A A +E AE K E Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 129 EQKKAAEAKK-----AEEAKKA--AEKQQADIAKKKAE-EEAKKQAEEEAKKQAAEEAKK 180 ++ A E A+EAK A Q ++A+ +E +E + +E EE K Sbjct: 1054 NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAK 1113 Query: 181 KAAEDAKKKAAEDAKKKAAAEEAKKKAAEEAKKKAAADAQKKKAQEAARKAAEDKKAQAL 240 E ++ K ++ + K+ E + A A++ ++ A Sbjct: 1114 VETEKTQEVP------KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 241 AELLSDTTER 250 E + T Sbjct: 1168 TEQPAKETSS 1177 Score = 57.8 bits (139), Expect = 4e-11 Identities = 29/183 (15%), Positives = 67/183 (36%), Gaps = 10/183 (5%) Query: 78 RQTEVEQMEQKKVEQEAVKAAEQKKADAAQKAEEAR--EAAEAKKAEEAAKAAEQKKAAE 135 T + + + +V + ++ A +A A ++ E A+ ++Q+ Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIA-RVDEAPVPPPAPATPSETTETVAENSKQESKTV 1051 Query: 136 AKKAEEAKKAAEKQQADIAKKKAEEEAKKQAEEEAK-KQAAEEAKKKAAEDAKKKAAEDA 194 K ++A + + + + K+ +A Q E A+ +E + ++ E+ Sbjct: 1052 EKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE- 1110 Query: 195 KKKAAAEEAKKKAAEEAKKKAAADAQKKKAQEAARKAAEDKKAQALAELLSDTTERQQAL 254 KA E K +E K + + K++ E + AE + + + + Sbjct: 1111 --KAKVETEKT---QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT 1165 Query: 255 ADE 257 AD Sbjct: 1166 ADT 1168 Score = 52.0 bits (124), Expect = 2e-09 Identities = 29/205 (14%), Positives = 69/205 (33%), Gaps = 8/205 (3%) Query: 43 SKPIVQATLYQLKSKSQATTQTNQKIAGEAKKTASRQTEVEQMEQKKVEQEAVKAAEQKK 102 +K V+A + +Q+ ++T + E K+TA VE+ E+ KVE E + + Sbjct: 1072 AKSNVKANTQTNE-VAQSGSETKETQTTETKETA----TVEKEEKAKVETEKTQEVPKVT 1126 Query: 103 ADAAQKAEEAREAAEAKKAEEAAKAAEQKKAAEAKKAEEAKKAAEKQQADIAKKKAEEEA 162 + + K E++ + E A+ + + +++ A +Q A E+ Sbjct: 1127 SQVSPKQEQSE---TVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 163 KKQAEEEAKKQAAEEAKKKAAEDAKKKAAEDAKKKAAAEEAKKKAAEEAKKKAAADAQKK 222 + E + + ++ K + + + A + Sbjct: 1184 TESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSND 1243 Query: 223 KAQEAARKAAEDKKAQALAELLSDT 247 ++ A L++ + Sbjct: 1244 RSTVALCDLTSTNTNAVLSDARAKA 1268 Score = 37.7 bits (87), Expect = 7e-05 Identities = 23/122 (18%), Positives = 44/122 (36%), Gaps = 6/122 (4%) Query: 146 AEKQQADIAKKKAEEEAKKQAEEEAKKQAAEE-AKKKAAEDAKKKAAEDAKK-KAAAEEA 203 EK+ + QA+ + EE A+ A A ++ + AE + Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 204 KKKAAEEAKKKAAADA----QKKKAQEAARKAAEDKKAQALAELLSDTTERQQALADEQG 259 K+++ K + A ++ A+EA + + +A+ S+T E Q E Sbjct: 1045 KQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA 1104 Query: 260 DQ 261 Sbjct: 1105 TV 1106
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 157 bits (398), Expect = 3e-52 Identities = 50/147 (34%), Positives = 79/147 (53%) Query: 8 SEEDRKSIVDGLSRLLSDTYVLYLKTHNFHWNVTGPSFRTLHLMFEEQYNELALAVDSIA 67 ++ ++ + + L+ LS+ ++LY K H FHW V GP F TLH FEE Y+ A VD+IA Sbjct: 6 AKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIA 65 Query: 68 ERIRALGFPAPGSYAFYARHSSIKEEEGVPPAEEMIRQLVQGQEAVVRTARSIFPVVDKV 127 ER+ A+G + Y H+SI + A EM++ LV + + ++ + + ++ Sbjct: 66 ERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEEN 125 Query: 128 SDEPTADLLTQRMQVHEKTAWMLRVLL 154 D TADL ++ EK WML L Sbjct: 126 QDNATADLFVGLIEEVEKQVWMLSSYL 152
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.0 bits (72), Expect = 0.009 Identities = 19/78 (24%), Positives = 31/78 (39%) Query: 493 KEVAKPAAANVESSATPAAEGDPEGAKSASNKIAAASEPAKEGAQASQTAQPTPDSASAP 552 +E+AK A S TP A+ + A ++P + A +T + P + Sbjct: 453 EELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETA 512 Query: 553 EPRGVGAAMKVLAKPAVL 570 P AA+ V+A V Sbjct: 513 NPFFTAAALTVMATAGVA 530
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.8 bits (80), Expect = 2e-04 Identities = 15/82 (18%), Positives = 28/82 (34%), Gaps = 15/82 (18%) Query: 129 LNSKEVVIFAAGTGNPFFTT-------------DSAACLRAIEIDADVVLKATKVDGVYT 175 + +VI + G G P D A A E++AD+ + T V+G Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 176 ADPFKDPHAEKFDHLSYDEVLD 197 + + + +E+ Sbjct: 243 Y--YGTEKEQWLREVKVEELRK 262
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.2 bits (81), Expect = 5e-04 Identities = 31/116 (26%), Positives = 47/116 (40%), Gaps = 14/116 (12%) Query: 288 LLCFAVVFMALATPLSAWLSDRYGRKPVLVVGGLLAIASGFTMEPLLTSGSTTGVALFLA 347 L +A++ A A P+ LSDR+GR+PVL+V A M +T L Sbjct: 49 LALYALMQFACA-PVLGALSDRFGRRPVLLVSLAGAAVDYAIM-------ATAPFLWVLY 100 Query: 348 IELFLMGVTFAPM---GALLPELFPTH--VRYTG-ASAAYNLGGIVGASAAPFFAQ 397 I + G+T A GA + ++ R+ G SA + G + G Sbjct: 101 IGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG 156 Score = 29.0 bits (65), Expect = 0.043 Identities = 63/301 (20%), Positives = 104/301 (34%), Gaps = 63/301 (20%) Query: 80 SALFGHFGDRIGRKSTLVASLLLMGVSTTLIGVLPGYDSIGVWAPIILCLLRFGQGLGLG 139 + + G DR GR+ L+ SL V ++ P +W +L + R G+ G Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLW---VLYIGRIVAGIT-G 110 Query: 140 GEWGGAALLATENAPQGKRA-WFGMFPQ-------LGPSIGFLAANGLFLTLALVLSDEQ 191 A + +RA FG GP +G L Sbjct: 111 ATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG--------------- 155 Query: 192 FREWGWRIPFLLSAALVLVGLYVRL-------KLEESPVFAKAVA-----RHERVKMPVV 239 + PF +AAL + K E P+ +A+ R R V Sbjct: 156 --GFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVA 213 Query: 240 DLFARYWLPTLLGAAAMVVCYALFYISTVFSLSYGVTTLGYSRETFLGLLCFAVVFMALA 299 L A +++ L+G AL+ I + TT+G S + A+ Sbjct: 214 ALMAVFFIMQLVGQVPA----ALWVIFGEDRFHWDATTIGIS---LAAFGILHSLAQAMI 266 Query: 300 T-PLSAWLSDRYGRKPVLVVGGLLAIASGFTMEPLLTSGSTTGVALFLAIELFLMGVTFA 358 T P++A L +R ++ G++A +G+ +L + +T G F + L G Sbjct: 267 TGPVAARLGERR-----ALMLGMIADGTGY----ILLAFATRGWMAFPIMVLLASGGIGM 317 Query: 359 P 359 P Sbjct: 318 P 318
>PF05860#haemagglutination activity domain. Length = 117 Score = 80.2 bits (198), Expect = 7e-20 Identities = 23/136 (16%), Positives = 41/136 (30%), Gaps = 21/136 (15%) Query: 63 LTPTPGPGGTPIIDNGHGVPVIDIVAPNASGLSHNQFLDYNVGKQGVVLNNALQAGQSQL 122 +TP I +I+ S L H+ F +++V G N Sbjct: 3 ITPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFN--------- 52 Query: 123 AGQLGANPQFQGQAASTILNEVISQNASRIEGAQEIFGQKADYLLANPNGITVNGGSFIN 182 I++ V + S I+G A+ L NPNGI + ++ Sbjct: 53 ----------NPTNIQNIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNARLD 101 Query: 183 TTRAGFVVGNAHVQDG 198 + ++ Sbjct: 102 IGGSFVGSTANRLKFA 117
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.9 bits (67), Expect = 0.004 Identities = 14/43 (32%), Positives = 26/43 (60%), Gaps = 3/43 (6%) Query: 3 RRQAGMTLIELLVALALTALLGVLLSALVNGWLKVRERLDEQV 45 +Q G TL+E++V + ++GVL S +V + +E+ D+Q Sbjct: 5 DKQRGFTLLEIMVVI---VIIGVLASLVVPNLMGNKEKADKQK 44
>PilS_PF08805#PilS N terminal Length = 185 Score = 31.8 bits (72), Expect = 3e-04 Identities = 10/39 (25%), Positives = 19/39 (48%) Query: 2 KRGQRGFTLLEVSVALGIAAVLAVITSQVLRQRLAVQDT 40 K +G TL+EV + +G+ VLA ++ + + Sbjct: 22 KEQDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQS 60
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 40.7 bits (95), Expect = 4e-07 Identities = 22/89 (24%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 4 QRGFSLLELLVVLAIAALMTSLAVAWLDSGRSSVD-QTLDRLAAATVAQADLARHAGQLR 62 QRGF+LLE++++L + + + + + R QTL R A GQ Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQFF 62 Query: 63 GIRWNGQRPEFVRRQGDQWQVEAVALGDW 91 G+ + R +F+ + A A W Sbjct: 63 GVSVHPDRWQFLVLEARDGADPAPADDGW 91
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 214 bits (546), Expect = 5e-75 Identities = 71/142 (50%), Positives = 98/142 (69%), Gaps = 3/142 (2%) Query: 3 QRRNRQGGFTLMEIMVVIFIIGLLIAVVAPSVLGNQDKAMKQKVMADLATLEQALDMYRL 62 + ++Q GFTL+EIMVVI IIG+L ++V P+++GN++KA KQK ++D+ LE ALDMY+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 63 DNLRFPSNEQGLAALAKKPTQEPLPRSWRSDGYIRRLPEDPWGTPYQYRMPGEHGRVDVY 122 DN +P+ QGL +L + PT PL ++ +GYI+RLP DPWG Y PGEHG D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 123 SLGADGQPGGEGLDADLGNWAL 144 S G DG+ G E D+ NW L Sbjct: 122 SAGPDGEMGTED---DITNWGL 140
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 431 bits (1110), Expect = e-152 Identities = 171/404 (42%), Positives = 249/404 (61%), Gaps = 10/404 (2%) Query: 1 MPTYRYQAVDMSGKAHKASVQADSERHARQLLREQGLF--------ARQLQRHDS--TQS 50 M Y YQA+D GK + + +ADS R ARQLLRE+GL Q + + + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 51 RRQRLTRAQLCELTRQLATLIGAGIPLVDALATLERQLRQPALHAVLVTLRGSLAEGLGL 110 R+ RL+ + L LTRQLATL+ A +PL +AL + +Q +P L ++ +R + EG L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 111 ARSLARQGAPFTGLYCALVEAGERSGRLGQVLARLADHLEQVQRQRHKARTALIYPAVLM 170 A ++ F LYCA+V AGE SG L VL RLAD+ EQ Q+ R + + A+IYP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 171 GVSLAVVIGLMTFVVPKLTEQFAHSGQSLPLITSLLIGISQGLVHAGPYLLALAIGLAVA 230 V++AVV L++ VVPK+ EQF H Q+LPL T +L+G+S + GP++L + +A Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 231 GGWLLRKPHWRLRRDDLLLRLPRVGALLQVLESARLARSLAILCGSGVALLEALQVATET 290 +LR+ R+ LL LP +G + + L +AR AR+L+IL S V LL+A++++ + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 291 IGNLRIHAAMAQVRQQVQGGTSLHRALDGAGQFPPLLVNMVGSGEASGTLADMLERVADD 350 + N ++ V+ G SLH+AL+ FPP++ +M+ SGE SG L MLER AD+ Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 351 QERGFARQVDTAMALFEPLMILVMGAVVLFIVLAVLLPIMQLNQ 394 Q+R F+ Q+ A+ LFEPL+++ M AVVLFIVLA+L PI+QLN Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNT 404
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 521 bits (1342), Expect = e-180 Identities = 222/604 (36%), Positives = 346/604 (57%), Gaps = 28/604 (4%) Query: 18 YEVNFVDTELSEFIDSVSRITGTTFIVDPRVQGKVTVRTVDRHDADAIYDIFLAQLRAQG 77 + +F T++ EFI++VS+ T I+DP V+G +TVR+ D + + Y FL+ L G Sbjct: 30 FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDVYG 89 Query: 78 FAAVDLPNGSVKIVPDQAARLEPVPVESAGKKSEGSDGVATRVFNVRNAASEQMLGILKP 137 FA +++ NG +K+V + A+ VPV S G D V TRV + N A+ + +L+ Sbjct: 90 FAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIG-DEVVTRVVPLTNVAARDLAPLLRQ 148 Query: 138 LIDPR-VGVITPYPAANLLVVTDWRSNLERIDSLLRQLDQVSDEPLQVIPLKHASAADTA 196 L D VG + Y +N+L++T + ++R+ +++ ++D D + +PL ASAAD Sbjct: 149 LNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADVV 208 Query: 197 GLVTRLLAREQ-----GSDAAQVVADPRSNALLVRGSADSRERVRALLAQLDRPGDNLRS 251 LVT L GS A VVAD R+NA+LV G +SR+R+ A++ QLDR Sbjct: 209 KLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQ--QATQ 266 Query: 252 SNTQVMYLRHANAAEVVKVLRGLSQAGAVPAAEGEGKDAAPVPAASDSGIRLEYEEGTNA 311 NT+V+YL++A A+++V+VL G+S + AA D I ++ TNA Sbjct: 267 GNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPV------AALDKNIIIKAHGQTNA 320 Query: 312 VVMVGPDSELAAFRSIVEQLDIRRAQVVVEAIIAEVSDSSAQELGVQWLFADEKFGAGIV 371 +++ + ++ QLDIRR QV+VEAIIAEV D+ LG+QW AG+ Sbjct: 321 LIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANK----NAGMT 376 Query: 372 NFGGNGVNIASIAGAASSGDNEKLGKLLSATTGATAGIGHIGGGF---NFAMLINALKGK 428 F +G+ I++ A + K G + S+ A + I GF N+AML+ AL Sbjct: 377 QFTNSGLPIST--AIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSS 434 Query: 429 SGFNLLSTPTLLTLDNAEASILVGQEVPFVTGSVTQNNANPYQTIERKEVGVKLRIKPQV 488 + ++L+TP+++TLDN EA+ VGQEVP +TGS T + N + T+ERK VG+KL++KPQ+ Sbjct: 435 TKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQI 494 Query: 489 NIDNSVRLDIVQEVSSIADSSAASD----VITNKREIKTKVMVEDNGLVILGGLISDELS 544 N +SV L+I QEVSS+AD+++++ N R + V+V V++GGL+ +S Sbjct: 495 NEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVS 554 Query: 545 TSNQRVPLLGDIPYLGRLFRSDASKNTKQNLMVFIRPRILRDGESLAGLSQQKYQSLQQD 604 + +VPLLGDIP +G LFRS + K +K+NLM+FIRP ++RD + S +Y + Sbjct: 555 DTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDA 614 Query: 605 TPLK 608 + Sbjct: 615 QSKQ 618
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 34.2 bits (78), Expect = 1e-05 Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 1/54 (1%) Query: 1 MGGIGIWQLVIVLLIVFLLFGTKRLKGLGSDVGEAIQGFRKSMGGTADNGVEQQ 54 M IG +L++V +I ++ G +RL V I+ R T N + Q+ Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLA-TTVQNELTQE 53
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 74.7 bits (183), Expect = 1e-20 Identities = 29/93 (31%), Positives = 47/93 (50%), Gaps = 7/93 (7%) Query: 1 MFEIGFTELLLVGIVALLVLGPERLPVAARTLGRGLGQARRALHALKTQVEREIDMPALD 60 MF+IGF+ELLLV I+ L+VLGP+RLPVA +T+ + R ++ ++ +E+ + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 -------AAPLQRLEQEIRQGIQLDATPANDPT 86 A L L E++ + A Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAAESMK 93
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 529 bits (1365), Expect = 0.0 Identities = 182/566 (32%), Positives = 294/566 (51%), Gaps = 12/566 (2%) Query: 277 LNGVCAAPGLALGPLARL--DGISLPADSGDNDPGEQHQALNSALAEVRHAIDRDWRHLP 334 + G+ A+ G+A+ + + S + E + L +AL + + + Sbjct: 5 ITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEK-LTAALEKSKEELRAIKDQTE 63 Query: 335 RGQ-EDAAAILEAHLALLDDPALLGDARQHIAC-GVAASHAWSRAIETQCQVLRSLGNPL 392 D A I AHL +LDDP L+ + I + A +A + + S+ N Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 393 LAERANDLYDLQQRVLRALLGETRQ--LRLPPAAIVVAHELTPSDLLLLARHDVAGLCMA 450 + ERA D+ D+ +RVL L+G + +++A +LTPSD L + V G Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATD 183 Query: 451 AGGATSHVAILARARGLPCLVAVGEALLDLPAGTPLVLDADQGRLETQAAPQRLAEVHCH 510 GG TSH AI++R+ +P +V E + G +++D +G + + + Sbjct: 184 IGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEK 243 Query: 511 LQQRREIRQRQQAAAQQGARTRDGQLIEVAANVASAEEAAQALALGADGIGLLRSEFLFI 570 + +Q + + T+DG +E+AAN+ + ++ LA G +GIGL R+EFL++ Sbjct: 244 RAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYM 303 Query: 571 DRPTAPDEAEQRNAYQAVLDAMAERPVIIRTIDVGGDKQLDYLPLPAEANPVLGLRGIRL 630 DR P E EQ AY+ V+ M +PV+IRT+D+GGDK+L YL LP E NP LG R IRL Sbjct: 304 DRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIRL 363 Query: 631 GQVRPELLDQQLRALLQVSPQRRCRIMLPMVTEVDELIAIRQRLDRLATEL-----GVTA 685 + ++ QLRALL+ S ++M PM+ ++EL + + +L V+ Sbjct: 364 CLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSD 423 Query: 686 RAELGVMIEVPAAALLAERLAEHADFFSIGTNDLSQYTLAMDRDHAGLAARVDALHPALL 745 E+G+M+E+P+ A+ A A+ DFFSIGTNDL QYT+A DR + ++ HPA+L Sbjct: 424 SIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAIL 483 Query: 746 RLIELTCQGAAKHGRWVGVCGALASDPLATPVLVGLGVAELSVSAPQIGEIKALVRQLDA 805 RL+++ + A G+WVG+CG +A D +A P+L+GLG+ E S+SA I ++ + +L Sbjct: 484 RLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLSK 543 Query: 806 GACRRFSQGLLGLASAGAARQACRDF 831 + F+Q L L +A Q + Sbjct: 544 EELKPFAQKALMLDTAEEVEQLVKKT 569
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 577 bits (1490), Expect = 0.0 Identities = 216/566 (38%), Positives = 335/566 (59%), Gaps = 14/566 (2%) Query: 398 TLQGVAAAPGIASGPAHVCVEREID-YPLRGESPGQERTRLRVAIDKVHADLQALVQRSD 456 + G+AA+ G+A A + +E +D E +L A++K +L+A+ +++ Sbjct: 4 KITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTE 63 Query: 457 KAIGE----IFVTHQEMLADPALTDDVEVRL-AQGESAAAAWMAVIESAARQQEALHDAL 511 ++G IF H +L DP L D ++ ++ + +A A V + E++ + Sbjct: 64 ASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEY 123 Query: 512 LAERAADLRDIGRRVLAQLCGVQ--AVVEPEQPYVLVMAEVGPSDVARLDPARVAGIVTA 569 + ERAAD+RD+ +RVL L GV+ ++ + V++ ++ PSD A+L+ V G T Sbjct: 124 MKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATD 183 Query: 570 QGGATAHSAIVARALGIPAVVGAGAAVLLLENGTPLLLDGQRGQVEVAPPEARLQRALAE 629 GG T+HSAI++R+L IPAVVG +++G +++DG G V V P E ++ + Sbjct: 184 IGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEK 243 Query: 630 RDARERRLQIAWANRHEPALTRDGHAVEVFANIGESSGIGKVVEQGAEGVGLLRTELIFM 689 R A E++ Q EP+ T+DG VE+ ANIG + V+ G EG+GL RTE ++M Sbjct: 244 RAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYM 303 Query: 690 AHPQLPDVATQEAEYRRVLDGLGGRPLVVRTLDVGGDKPLPYWPIATEENPFLGVRGVRL 749 QLP Q Y+ V+ + G+P+V+RTLD+GGDK L Y + E NPFLG R +RL Sbjct: 304 DRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIRL 363 Query: 750 TLQRPQVMEDQLRALLRAADNRPLRIMFPMVGQLHEWRAAKAMVERLRQEV------PVA 803 L++ + QLRALLRA+ L++MFPM+ L E R AKA+++ + ++ Sbjct: 364 CLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSD 423 Query: 804 DLQVGIMVEVPSAALLAPQLAREVDFFSIGTNDLTQYTLAIDRGHPSLSAQADGLHPAVL 863 ++VGIMVE+PS A+ A A+EVDFFSIGTNDL QYT+A DR + +S HPA+L Sbjct: 424 SIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAIL 483 Query: 864 NLIDMTVRAAHAQGKWVGVCGELAADPQAVPVLLGLEVDELSVAARSIPEVKALVRQADL 923 L+DM ++AAH++GKWVG+CGE+A D A+P+LLGL +DE S++A SI ++ + + Sbjct: 484 RLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLSK 543 Query: 924 STARALAREALQQDSAEAVRALVERY 949 + A++AL D+AE V LV++ Sbjct: 544 EELKPFAQKALMLDTAEEVEQLVKKT 569
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.9 bits (64), Expect = 0.029 Identities = 18/80 (22%), Positives = 31/80 (38%), Gaps = 4/80 (5%) Query: 160 LGSDNLEGLRVAVQGLGN-VGYALAEQLHAAGAELLVSDLDPGKVRLAVEQFSAHPVAHE 218 + + +EG + G +G A+A L + GA + D +P K+ V A E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 219 ALISTPCDIFAPCGVGPVLN 238 A P D+ + + Sbjct: 61 AF---PADVRDSAAIDEITA 77
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 51.4 bits (123), Expect = 4e-09 Identities = 43/179 (24%), Positives = 81/179 (45%), Gaps = 2/179 (1%) Query: 23 RLLLLLILLLVTDGYDAQVLGYVIPALAQDWGLEKAAFGPVFSANLLGLTVGSLAVTPLA 82 ++L+ L +L + VL +P +A D+ A+ V +A +L ++G+ L+ Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 83 DRFGVRRVLLCCVLLYASLTVLMVFASSLDS-LMLARFLCGIGMGGAMPSAMALMADYAP 141 D+ G++R+LL +++ +V+ S S L++ARF+ G G M ++A Y P Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIP 133 Query: 142 PRLRTLMVTLAACGFSLGGAAGGFVAAGFIDHHGWQAVFLAGGVAPLLLFPFLMLFLPE 200 R L ++G G + + W + L + ++ PFLM L + Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI-PMITIITVPFLMKLLKK 191
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 78.6 bits (193), Expect = 4e-19 Identities = 51/196 (26%), Positives = 86/196 (43%), Gaps = 13/196 (6%) Query: 7 LQERVVIVTGAGGGLGRAHALLFAARGAHVVVNDLGGSTHGEGANASAADRVVEEIRAAG 66 ++ ++ +TGA G+G A A A++GAH+ D N ++VV ++A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD---------YNPEKLEKVVSSLKAEA 56 Query: 67 GSAIANHDSVTDGARIVEQA---LDTFGRVDVLVNNAGILRDKTFHKMEDSDWELVYRVH 123 A A V D A I E G +D+LVN AG+LR H + D +WE + V+ Sbjct: 57 RHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVN 116 Query: 124 VEGAYKVTHAAWPHLRAQNWGRVIFTSSTSGIYGNFGQANYGMAKLGLYGLTRTLAIEGR 183 G + + + ++ + G ++ S A Y +K T+ L +E Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 184 KHGILVNAIAPTGGTR 199 ++ I N ++P G T Sbjct: 177 EYNIRCNIVSP-GSTE 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 8e-04 Identities = 15/77 (19%), Positives = 34/77 (44%), Gaps = 7/77 (9%) Query: 3 SPTGKAPTAADGPKWDVAEAVNQLSWDDLRIIKTLSDC-GNRAATAKKLGINVSTVSRRV 61 + A P + ++ + I+ L+ GN+ A LG+N +T+ +++ Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYP--LILAALTATRGNQIKAADLLGLNRNTLRKKI 470 Query: 62 AQVERTLGIALFDHRKS 78 R LG++++ +S Sbjct: 471 ----RELGVSVYRSSRS 483
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.0 bits (67), Expect = 0.026 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 3/60 (5%) Query: 279 YSTDPHNILPRRTNLRGSFDYI--YFDMGLEEEAKLSNQLADLIRSDDRLGSDERFVLFK 336 Y+ N+L ++ N+ G+ Y + G EE A N AD S+++ DE F +++ Sbjct: 74 YTHQMGNLLIQQANINGTIGYHTRFSGHGHEEHAPFDNHAAD-SASEEKGNVDEGFTVYR 132
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 55.7 bits (134), Expect = 5e-13 Identities = 21/62 (33%), Positives = 39/62 (62%), Gaps = 1/62 (1%) Query: 1 MKGQRGITLIELMIVVAIIGILATIAIPMYTNHQARAKAAAALLEISALKTPMDI-RLNE 59 QRG TL+E+M+V+ IIG+LA++ +P ++ +A A+ +I AL+ +D+ +L+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 60 GK 61 Sbjct: 64 HH 65
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 392 bits (1008), Expect = e-137 Identities = 122/405 (30%), Positives = 211/405 (52%), Gaps = 10/405 (2%) Query: 7 LYAWEGIDASGVRQHGQQAGRSPAFVQAWLQRQGIRATRVRLA---------GGLQWRWP 57 Y ++ +DA G + G Q S + L+ +G+ V GL R Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 58 QRAGKADAPGFSRQLATLLTAGVPLLQAFEVMARSTVDSGMAALLARLKQDVAAGLGLAE 117 R +D +RQLATL+ A +PL +A + +A+ + ++ L+A ++ V G LA+ Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 118 ALQRHPTWFDALYCNLVRVGEQSGTLDRQLEQMAGMLEKRQALRQKVRKAMLYPALLLLT 177 A++ P F+ LYC +V GE SG LD L ++A E+RQ +R ++++AM+YP +L + Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 178 GLGVAALLLLEVVPRFQGLFASFDKALPAFTQWVIDLSTGLGNHVGWLVLLITVLGVGGR 237 + V ++LL VVP+ F +ALP T+ ++ +S + W++L + + R Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 238 EVYRRHLPTRLWMVRWGLRVPVVGTLLGQAALARFARSLATSYSAGVALLDALATVAPVS 297 + R+ R+ R L +P++G + AR+AR+L+ ++ V LL A+ V Sbjct: 243 VMLRQE-KRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVM 301 Query: 298 GNCLHERAILALRQGVANGASLQQAMDADGLFPPLLRQLVAVGEASGTLDTMLDKAALHY 357 N + V G SL +A++ LFPP++R ++A GE SG LD+ML++AA + Sbjct: 302 SNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQ 361 Query: 358 EEQVSQALEQLTTLLEPAIVLILGLLVGGLVVAMYLPIFQLGSLI 402 + + S + L EP +V+ + +V +V+A+ PI QL +L+ Sbjct: 362 DREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 335 bits (860), Expect = e-118 Identities = 157/276 (56%), Positives = 197/276 (71%), Gaps = 2/276 (0%) Query: 10 HPPFFYALAAVLGLLVGSFLNVLVYRLPLMLERQWQREAQEVLGLPQA--EHERFDLCLP 67 P +++L + L++GSFLNV+++RLP+MLER+WQ E + + ++L +P Sbjct: 11 LPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPPYNLMVP 70 Query: 68 ASRCPHCQRPIRAWENIPVLSYVALRGRCSGCKARISARYPLVELATALLSLLVAWHFGP 127 S CPHC PI A ENIP+LS++ LRGRC GC+A ISARYPLVEL TALLS+ VA P Sbjct: 71 RSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAVAMTLAP 130 Query: 128 GVEALAVMLLTWGLIGLSLIDAEHQLLPDVLVLPLLWLGLVVNAFGLLVPLADAVWGAVA 187 G LA +LLTW L+ L+ ID + LLPD L LPLLW GL+ N G V L DAV GA+A Sbjct: 131 GWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMA 190 Query: 188 GYLSLWTVYWVFKLVTGKEGMGFGDFKLLAMLGAWGGWQILPLTLMLASLVGALIGLTLV 247 GYL LW++YW FKL+TGKEGMG+GDFKLLA LGAW GWQ LP+ L+L+SLVGA +G+ L+ Sbjct: 191 GYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLI 250 Query: 248 RLKRTQMGAALPFGPYLAIAGWIAVLWGDEIVASYL 283 L+ +PFGPYLAIAGWIA+LWGD I YL Sbjct: 251 LLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 88.2 bits (218), Expect = 8e-22 Identities = 64/255 (25%), Positives = 111/255 (43%), Gaps = 16/255 (6%) Query: 211 LAGRHALVTGAARGIGAAIAETLSRDGAEVTLLDVPQAQRDLDALAARLGGR---ALALD 267 + G+ A +TGAA+GIG A+A TL+ GA + +D + + + + R A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 268 ICASDAAAQL---LEALPQGLDIVVHNAGITRDKTLANMTPEYWDAVLAVNLKAPQVLTE 324 + S A ++ +E +DI+V+ AG+ R + +++ E W+A +VN + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 325 ALFEGGKLHAGARITLLASVSGIAGNRGQSNYAASKAGLIGFAQAWAPRLADQGASINAV 384 ++ + I + S + YA+SKA + F + LA+ N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 385 APGFIETHM----------TAAMPMGLREAGRRLSSLGQGGLPQDVAEAIAWLSQPGSGT 434 +PG ET M + G E + L + P D+A+A+ +L +G Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 435 VNGQALRVCGQALMG 449 + L V G A +G Sbjct: 246 ITMHNLCVDGGATLG 260
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 28.2 bits (63), Expect = 0.014 Identities = 29/163 (17%), Positives = 53/163 (32%), Gaps = 35/163 (21%) Query: 4 IVLLMWLALCTEQDVRERQISNALTLGVAACALAWLFATGRSWIGADASEAGWALAIVML 63 ++L L T D+ + + + LTL + L LF ++ + G ++L Sbjct: 138 LLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGL--LFNLLGGFVSLGDAVIGAMAGYLVL 195 Query: 64 LTLPGYMLGR-------FGAGDVKLMGALALATSPQYVLGTF-----IGAGVTVLAWMFG 111 +L Y + G GD KL+ AL Q + +GA + + + Sbjct: 196 WSL--YWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAFMGIGLILLR 253 Query: 112 RRRLWTLLNPKVKKRLQALAEQVGDKQPFAPYVLAGFLLTAVW 154 + PF PY+ + +W Sbjct: 254 NHHQSKPI-------------------PFGPYLAIAGWIALLW 277
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.4 bits (214), Expect = 2e-21 Identities = 37/159 (23%), Positives = 69/159 (43%), Gaps = 10/159 (6%) Query: 9 KVLVVDDQPVIVEELCEFLESEGYRCVPAHSTGQAIACFKADETIGLILCDLHMPERDGI 68 +LV DD I L + L GY + A L++ D+ MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI-AAGDGDLVVTDVVMPDENAF 63 Query: 69 ELVRTLKQNAGPQRMFEAIMLTGRADKQDVIRALREGFADYYQKPMDLDELLEGVRRQEA 128 +L+ +K+ + ++++ + I+A +G DY KP DL EL+ + R Sbjct: 64 DLLPRIKK---ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR--- 117 Query: 129 ALLERRRNFRELGSLNQRLQEL---AESIDDLYQDLEKA 164 AL E +R +L +Q L + ++ ++Y+ L + Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL 156
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 33.0 bits (75), Expect = 4e-04 Identities = 11/67 (16%), Positives = 20/67 (29%) Query: 109 HGLGQLASARGDDVQALRNLQRAVRLAPTDEKVRNDLGVVQMNLGNHEQARFEFLTAIEL 168 + L G A + Q L D + LG + +G ++ A + + Sbjct: 40 YSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIM 99 Query: 169 KDDNPLP 175 P Sbjct: 100 DIKEPRF 106
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 122 bits (308), Expect = 3e-32 Identities = 64/266 (24%), Positives = 122/266 (45%), Gaps = 15/266 (5%) Query: 128 AQEDLPV-QVQADIRFVEVRRLKYKEAGARLFFKGSNNSLIGSPGTVPDTVVRPGYVPST 186 AQ D+ QV + EV+ G + K + + + G +P + G Sbjct: 338 AQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGMTQFTNSG-LPISTAIAGANQYN 396 Query: 187 TTAPGSTNYADARPGIPLDNSVFN-IVWGGGSSRFLAMINALENSGFAYTLARPSLTVLS 245 S++ A A S FN I G + ++ AL +S LA PS+ L Sbjct: 397 KDGTVSSSLASAL-------SSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLD 449 Query: 246 GLTASFLAGGEIPIPVPS--SGSDNV--SIEYKEFGVRLALTPTVVSRNRITLKVAPEVS 301 + A+F G E+P+ S + DN+ ++E K G++L + P + + + L++ EVS Sbjct: 450 NMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVS 509 Query: 302 ELDFNNSVVIAGTRVPGLSVRRTDTSISLADGESFIISGLISSNVRSNVDKMPGLGNLPI 361 + + + + + R + ++ + GE+ ++ GL+ +V DK+P LG++P+ Sbjct: 510 SVA-DAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPV 568 Query: 362 IGAFFRQSALNREETELLMIVTPHLV 387 IGA FR ++ + L++ + P ++ Sbjct: 569 IGALFRSTSKKVSKRNLMLFIRPTVI 594
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 28.7 bits (64), Expect = 0.010 Identities = 16/57 (28%), Positives = 25/57 (43%), Gaps = 7/57 (12%) Query: 3 SRLTMILAGLFLIAALLAGYW-------GLRLSRPAEPAPAPLAPPSEAAIPAAPVP 52 +R+T +LA LF I +L+ G G + PA P+ A P + +P Sbjct: 53 TRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPAKPTSDIP 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.0 bits (213), Expect = 7e-23 Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 3/106 (2%) Query: 7 RQQILLVDDEEEALLELAELLENEGFCCHTATSVRGALQQLTRHPDVALVITDLRMPEES 66 IL+ DD+ L + L G+ ++ + + LV+TD+ MP+E+ Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDEN 61 Query: 67 GLGLVQRLREHTARQHLPVIVMSGHADMDDVSDLLRLQVLDLFRKP 112 L+ R+++ R LPV+VMS D KP Sbjct: 62 AFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>INTIMIN#Intimin signature. Length = 939 Score = 41.2 bits (96), Expect = 6e-05 Identities = 72/373 (19%), Positives = 118/373 (31%), Gaps = 38/373 (10%) Query: 1452 SDGGITWTATFTPTNNITDSTNLITLDNSGVVGASSGNAGSGTTNSNNYAIDTQRPTATI 1511 +DG T T T N N+ N V G + +A S TN + A T + Sbjct: 572 ADGTEAITYTATVKKNGVAQANVPVSFNI-VSGTAVLSANSANTNGSGKATVTLKSDKPG 630 Query: 1512 VVADSNLAIGQTSLVTITFSEAVTGFTNADLTIANGTLSAVSSSDGGVTWTATLT----P 1567 V S TS + V + I +AV++ +T+T + P Sbjct: 631 QVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKP 690 Query: 1568 AAG--ITDTSNLITLDNTGVTDIAGNAGTGSTDSN------------NYAVDSQRPTATI 1613 + +T T+ L L N+ + S + AVD + P Sbjct: 691 VSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEF 750 Query: 1614 VIADPNLTAGETTTVTFTFSEAVTGFTNADLSVANGTLSAVSSSDGGITWTATFTPSNGV 1673 + G V L L A S +G TW + V Sbjct: 751 -FTTLTIDDGNIEIVGTGVKG---KLPTVWLQYGQVNLKA-SGGNGKYTWRSANPAIASV 805 Query: 1674 RDLSNVITLNNTGVSDLAGNAGVGTTSSANYTVDTVVPTATVVVADTALRV----GETSL 1729 S +TL G + ++ + +A YT+ T +++V + + RV + Sbjct: 806 DASSGQVTLKEKGTTTISVIS--SDNQTATYTIAT---PNSLIVPNMSKRVTYNDAVNTC 860 Query: 1730 VTITFSEAVSGFTLADLSVANGTLSGLSSSDGGITWTATLTPT-----SNVEDTSNLITL 1784 S L ++ A G + T + + T S V T +L+ Sbjct: 861 KNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQTAQDAKSGVASTYDLVKQ 920 Query: 1785 DNTGVVGASSGNA 1797 + + AS NA Sbjct: 921 NPLNNIKASESNA 933 Score = 37.0 bits (85), Expect = 0.001 Identities = 70/394 (17%), Positives = 122/394 (30%), Gaps = 34/394 (8%) Query: 1296 AIDTQRPTATIVMADSNLTVGETTTVTI----TFSEAVSGFTLADLTAPNGTLSGLSSSD 1351 + + TA + N + T+T+ + V + D TA S + Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVG---VTDFTAD--KTSAKADGT 575 Query: 1352 GGITWTATFTPTVNVQDTTNVITLNNTGVADLAGNAGAGTTTSANYTVSTLQPTATVVVS 1411 IT+TAT Q V +G A L+ N+ A T S TV TL+ V Sbjct: 576 EAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANS-ANTNGSGKATV-TLKSDKPGQVV 633 Query: 1412 NPALRVGDTSLVTFTFSEAVSGFTNADLTVANGTLSAVSSSDGGITWTATFTPTNNITDS 1471 A TS + V + + +AV++ IT+T + + Sbjct: 634 VSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSN 693 Query: 1472 TNLITLDNSGVVGASSGNAGSGTTNSNNYAIDTQ-RPTATIVVADSNLAIGQTSL----- 1525 + G + S+ + T + + V+D + + + Sbjct: 694 QEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTT 753 Query: 1526 VTITFSEAVTGFTNADLTIANGTLS------AVSSSDGGVTWTATLTPAAGITDTSNLIT 1579 +TI T + L S +G TW + A + +S +T Sbjct: 754 LTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVT 813 Query: 1580 LDNTGVTDIAGNAGTGSTDSNNYAVDSQRPTATIVIADPNLTAGETTTVTFTFSEAVTGF 1639 L G T I+ + D+Q T TI + + + VT+ + Sbjct: 814 LKEKGTTTISVISS-----------DNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKN 862 Query: 1640 TNADLSVANGTLSAVSSSDGGITWTATFTPSNGV 1673 L + L V + G + S + Sbjct: 863 FGGKLPSSQNELENVFKAWGAANKYEYYKSSQTI 896 Score = 34.7 bits (79), Expect = 0.006 Identities = 53/278 (19%), Positives = 85/278 (30%), Gaps = 19/278 (6%) Query: 1146 SDGGITWTATFTPTSAITDATNVITLDNTGVTDAAGNAGAGTTDSNNFAIDTQRPTATIA 1205 +DG T T T NV N A +A + T+ + A T + Sbjct: 572 ADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQ 631 Query: 1206 VADSNLAIGQTSLVTITFSEAVTGFSNADLSVANGTLSAVSSSDGGITWTATFTPTSAIT 1265 V S TS + V + + +AV++ IT+T Sbjct: 632 VVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPV 691 Query: 1266 DATNVITLDNTGV--------TDAAGNAGAGTTDSNNYAIDTQRPTATIVMADSNLTVGE 1317 V T T TD G A T + + + + V Sbjct: 692 SNQEV-TFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEF 750 Query: 1318 TTTVTITFSEAVSGFTLADLTAPNGTLSG------LSSSDGGITWTATFTPTVNVQDTTN 1371 TT+TI T P L S +G TW + +V ++ Sbjct: 751 FTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSG 810 Query: 1372 VITLNNTGVADLAGNAGAGTTTSANYTVSTLQPTATVV 1409 +TL G + + + +A YT++T P + +V Sbjct: 811 QVTLKEKGTTTI--SVISSDNQTATYTIAT--PNSLIV 844
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 14/59 (23%), Positives = 25/59 (42%), Gaps = 6/59 (10%) Query: 91 DMALLPAWCGRGIGSRLL---VQWLAQADADGLSAGLHVTPHN-PALRLYQRCGFEVVG 145 D+A+ + +G+G+ LL ++W + GL L N A Y + F + Sbjct: 94 DIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLM--LETQDINISACHFYAKHHFIIGA 150
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.042 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 4/30 (13%) Query: 29 LEPG----EALFLKGPSGSGKTTLLGLLGG 54 +EPG ++ L+G G GK+TL+ L G Sbjct: 589 MEPGCKFDYSVVLEGTGGIGKSTLINTLVG 618
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 28.6 bits (64), Expect = 0.018 Identities = 13/67 (19%), Positives = 22/67 (32%), Gaps = 2/67 (2%) Query: 488 DLVRGSLLLVFALILPVSAFMAMKITGVVVGPLGAAAQNAATTIPEAASVVAGIAMRVIS 547 +L LV L + I G++VG Q T+P ++ + Sbjct: 6 FAGNKALYLVLILSGWP--TIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLL 63 Query: 548 RGWSAAM 554 GW + Sbjct: 64 SGWYGEV 70
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 33.3 bits (76), Expect = 0.002 Identities = 16/88 (18%), Positives = 28/88 (31%), Gaps = 16/88 (18%) Query: 217 PFITLTQALGALPSLLGFAVPDET-MIRASGATLPA-------LDLARQAWASWLLGVVL 268 P + A+ + LL VP LP + A + + W+L +L Sbjct: 176 PCVLTVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALL 235 Query: 269 VYGLLPRLALAALCLWHWRQGRERLTLD 296 + R RQ + R++ Sbjct: 236 AGFMAFR--------VMLRQEKRRVSFH 255
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.9 bits (64), Expect = 0.050 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 282 DANAGDLPLLDGRWGDDLFNPETLKLLGVRLGSGVAAGAAA--GAGVDLLVGGLTLGAAA 339 D N +P + L L G + G AAG AA GA V L + G A Sbjct: 205 DTNVTAVPASGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAP 264 Query: 340 LAGAIAGGALQ 350 GA+ GGA+ Sbjct: 265 AGGAVPGGAVP 275
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 35.1 bits (80), Expect = 3e-04 Identities = 18/49 (36%), Positives = 24/49 (48%) Query: 101 EAVNTTLSCAGAVIGWFVVFSGTIAAPFSGGTSLVLTYIGGAAATASSI 149 E N + C G V+G + +AA F+GG SL L +G A A I Sbjct: 308 EETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEI 356
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 37.8 bits (87), Expect = 3e-04 Identities = 47/160 (29%), Positives = 65/160 (40%), Gaps = 39/160 (24%) Query: 51 ERFLREGRTLARL-----------AHPNIATIHDI-----GNVGELYYMAMEYLPDG--- 91 ER + EG A L HPN+A +H + GN E + E DG Sbjct: 165 ERSIAEGHLFAELEAYKHIYKTAGKHPNLANVHGMAVVPYGNRKEEALLMDEV--DGWRC 222 Query: 92 -----TLKERIADG-LTPEQGLAYVRQIAQAL----GYAHAQGLVHRDVKPANILF-RAD 140 TL + G + E ++ IA L + G+VH D+KP N++F RA Sbjct: 223 SDTLRTLADSWKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRAS 282 Query: 141 GTAVLSDFGIAKSLDDRTQFTQAGFAVGTPSYMSPEQARG 180 G V+ D G L R+ GF T S+ +PE G Sbjct: 283 GEPVVIDLG----LHSRSGEQPKGF---TESFKAPELGVG 315
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 66.5 bits (162), Expect = 4e-14 Identities = 40/160 (25%), Positives = 73/160 (45%), Gaps = 35/160 (21%) Query: 283 PVVQPKPVERPRLAGFLAEDIKAGRVAVEDAVDRSVVTIRGDELFASASASIKGDFEPLM 342 PVV P P P + + T++ D LF A++K + + + Sbjct: 198 PVVAPAPAPAP------------------EVQTKHF-TLKSDVLFNFNKATLKPEGQAAL 238 Query: 343 LRIADAVAKVK---GNVKVTGHSDNQRIATLRFPSNWALSQARAEEVKNLLAARTGQPGR 399 ++ ++ + G+V V G++D RI + + N LS+ RA+ V + L ++ + Sbjct: 239 DQLYSQLSNLDPKDGSVVVLGYTD--RIGSDAY--NQGLSERRAQSVVDYLISKGIPADK 294 Query: 400 FSAQGLSDTEPLASN--DSAQGR-------AKNRRVEITV 430 SA+G+ ++ P+ N D+ + R A +RRVEI V Sbjct: 295 ISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>PF06872#EspG protein Length = 398 Score = 28.5 bits (63), Expect = 0.031 Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 3/47 (6%) Query: 187 GNWRPTLTAEQLAQVQE---VIHPVVRTHPENGRKALFVSEGFTTRI 230 G W P + ++ Q Q V+ PV H E GR S+G + RI Sbjct: 61 GLWNPKYSQDERQQFQGLLTVLEPVSPAHNELGRVYAKFSDGSSLRI 107
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 317 bits (814), Expect = e-106 Identities = 109/426 (25%), Positives = 205/426 (48%), Gaps = 9/426 (2%) Query: 41 PRVVRLTIWGVIAFFLFLIIWASVAPIDEVTRGEGKAIPSSKVQKIQNLEGGIVAEIFAK 100 R RL + ++ F + I + + ++ V GK S + ++I+ +E IV EI K Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 101 EGEIVEVGQPLLRLDETRFASNVDETEASRLAMALRVQRLTAEVE----DKPLQI----D 152 EGE V G LL+L ++ +T++S L L R +K ++ + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 153 EELRKAAPSQAANEQSLYQSRRQQLQDELGGLQQQLVQKQQELREFNSKRAQYANSLQLL 212 + + + SL + + Q++ + L +K+ E ++ +Y N ++ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 213 RQEIAMSEPLVAQGAISQVEVLRLRRAEVENRGQMDSTALAIPRAEAAIKEVESKIEETR 272 + + L+ + AI++ VL VE ++ + + E+ I + + + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 273 GKFRSEALTQLNEARTELNKATATSKALDDRVHRTMVTSPVRGIVKQLLVNTIGGVIQPG 332 F++E L +L + + T ++R +++ +PV V+QL V+T GGV+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 333 SDIIEIVPLDDTLVVEAKILPKDIAFLHPGQEATVKFTAYDYTIYGGMKAKLEQIGADTI 392 ++ IVP DDTL V A + KDI F++ GQ A +K A+ YT YG + K++ I D I Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413 Query: 393 TDEDKKTTYYLIKLRTDKSHLGTDEKPLLIIPGMVATVDIMTGKKTIMSYLLKPIIKARS 452 D+ + + + + +++ L T K + + GM T +I TG ++++SYLL P+ ++ + Sbjct: 414 EDQ-RLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVT 472 Query: 453 EALRER 458 E+LRER Sbjct: 473 ESLRER 478
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 100 bits (249), Expect = 3e-23 Identities = 64/264 (24%), Positives = 98/264 (37%), Gaps = 30/264 (11%) Query: 4909 LKPYDTDGKPQTNIDPSKLAEAILGHTEVTQPGNDTVNGGDGNDIIFGDLMVFDGVAGTG 4968 +T + + + + I N T GD + A Sbjct: 229 WGENETGADYNGHYGGAPMIDDIAAIQR-LYGANMTTRTGDSVYGFNSNTDRDFYTATDS 287 Query: 4969 VEAIRGYVADKLGVDSGSVDARAMHKYITENYAEFDVSRSNDGADTLLGGNGNDIIFGQG 5028 +A+ V D G D FD S ++ L + G Sbjct: 288 SKALIFSVWDAGGTD------------------TFDFSGYSNNQRINLNEGSFSDVGGLK 329 Query: 5029 GNDYIDGGKGNDILLGGTGNDTLLGGEGNDILFGGAGNDILIGGKGDDIMTGGSGADIFV 5088 GN I G + +GG+GND L+G ++IL GGAGND+L GG G D + GG+G D FV Sbjct: 330 GNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFV 389 Query: 5089 WKAGDL----GKDVIKDFKASEGDRLDLSDLLQGEKASTIDNFLKITTVNGESTLQVSTE 5144 + +G D I DF+ D++DLS + S + + T E LQ Sbjct: 390 YGSGQDSTVAAYDWIADFQKG-IDKIDLSAFRNEGQLSFVQ--DQFTGKGQEVMLQWDAA 446 Query: 5145 GKL----NAAGGLANADVTIKLEG 5164 + G ++ D +++ G Sbjct: 447 NSITNLWLHEAGHSSVDFLVRIVG 470
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 38.5 bits (89), Expect = 7e-05 Identities = 33/108 (30%), Positives = 49/108 (45%), Gaps = 12/108 (11%) Query: 538 KTDKKAQRQAAAALR---QQLAPHKKAADK----LETELNQVHQQLAEIEAALG----DS 586 + D A R+A L Q+L K ++ L +L+ + ++EA + Sbjct: 315 RRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQN 374 Query: 587 GLYEASRKDELRDLLARQTKLKQREGELEEAWMEALETLESMQAELEA 634 + EASR+ RDL A + KQ E LEEA + L LE + ELE Sbjct: 375 KISEASRQSLRRDLDASREAKKQVEKALEEANSK-LAALEKLNKELEE 421
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.7 bits (103), Expect = 7e-07 Identities = 17/117 (14%), Positives = 33/117 (28%), Gaps = 9/117 (7%) Query: 77 GDHVKANQVLARLDP-------KDLQNNVDSAKAEVFAEQARVTQASAAFVRQQKLLPKG 129 G+ V+ VL +L Q+++ A+ E Q + + KL + Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 130 YTSQSEYDSAEAALRSSQSALKAAQAQLANANEQLSYTALVSEADGVITARQAEVGQ 186 Y + + Q Q +L+ +E V+ Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK--ELNLDKKRAERLTVLARINRYENL 229 Score = 39.4 bits (92), Expect = 2e-05 Identities = 17/123 (13%), Positives = 44/123 (35%), Gaps = 3/123 (2%) Query: 82 ANQVLARLDPKDLQNNVDSAKAEVFAEQARVTQASAAFVRQQKLLPKGYTSQSEYDSAEA 141 Q +A+ + +N A E+ ++++ Q + + K + T + + + Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESE-ILSAKEEYQLVTQLFKNEILDK 303 Query: 142 ALRSSQSALKAAQAQLANANEQLSYTALVSEADGVITARQA-EVGQVVQATMPIFSLAVD 200 LR + + +LA E+ + + + + + G VV + + + Sbjct: 304 -LRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE 362 Query: 201 GDR 203 D Sbjct: 363 DDT 365
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.0 bits (83), Expect = 2e-04 Identities = 20/135 (14%), Positives = 53/135 (39%), Gaps = 16/135 (11%) Query: 92 QNQLRAAEGDLAKVQAQWINAQANARRQQQLYDRGVGAQAQLDIAQTDLKTTGAALEQAR 151 N+LR + L +++++ ++A+ + QL+ + L+ T + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI---------LDKLRQTTDNIGLLT 315 Query: 152 SAVSQARDQLGYSTLRSDHAAVVTAWQAEA-GQTVSAGQAVVTLARPDVKEAVIDLPIPL 210 +++ ++ S +R+ + V + G V+ + ++ + P+ + + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIV-PEDDTLEVTALVQ- 373 Query: 211 AEQLNKDLTFTVASQ 225 NKD+ F Q Sbjct: 374 ----NKDIGFINVGQ 384 Score = 34.0 bits (78), Expect = 9e-04 Identities = 18/100 (18%), Positives = 30/100 (30%), Gaps = 7/100 (7%) Query: 62 VSGRIARRWLDVGARVSPGDTLATLDPTDQQNQLRAAEGDLAKVQAQWINAQANARRQQQ 121 + + + G V GD L L AE D K Q+ + A+ R Q Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALG-------AEADTLKTQSSLLQARLEQTRYQI 155 Query: 122 LYDRGVGAQAQLDIAQTDLKTTGAALEQARSAVSQARDQL 161 L + + + E+ S ++Q Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Score = 28.3 bits (63), Expect = 0.050 Identities = 17/91 (18%), Positives = 32/91 (35%), Gaps = 21/91 (23%) Query: 92 QNQLRAAEGDLAKVQAQWINAQANARRQQQ--------------LYDRGVG-------AQ 130 QNQ E +L K +A+ + A R + L + + Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE 258 Query: 131 AQLDIAQTDLKTTGAALEQARSAVSQARDQL 161 + A +L+ + LEQ S + A+++ Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAKEEY 289
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 490 bits (1262), Expect = e-159 Identities = 229/1052 (21%), Positives = 436/1052 (41%), Gaps = 69/1052 (6%) Query: 7 LSEWALKHQSFVWYLMFVGLLMGIFSYFNLGREEDPSFTIKTMVIQTRWPGATQDETLYQ 66 ++ + ++ F W L + ++ G + L + P+ + + +PGA Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 67 VTDRIEKKLEELDSLDYVKSYT-RPGESTVYVYLRDTTKAKDIPQIWYQVRKKIQDIRGQ 125 VT IE+ + +D+L Y+ S + G T+ + + T D QV+ K+Q Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGT---DPDIAQVQVQNKLQLATPL 117 Query: 126 FPAGIQGPG-FNDEFGDVFGSIYAFTADG--LTLRQLRDYVE-VARAEVREVPNIGKVEL 181 P +Q G ++ + + F +D T + DYV + + + +G V+L Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 182 IGTQDEVLYLNFSTRKLAALGIDQRQAMQALQQQNAVTPAGVIEAGPE------RISVRT 235 G Q + + L + + L+ QN AG + P S+ Sbjct: 178 FGAQYAMR-IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA 236 Query: 236 TGQFASEKDLQTVNLRIND--RFFRLADIADIERGYVDPPSPMFRFNGQTAIGLAIGMKA 293 +F + ++ V LR+N RL D+A +E G + + R NG+ A GL I + Sbjct: 237 QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV-IARINGKPAAGLGIKLAT 295 Query: 294 GANIEVFGAALKARMDSIVRDLPVGVGVHNVSDQAVVVKQAVGGFTSALFEAVVIVLAVS 353 GAN A+KA++ + P G+ V D V+ ++ LFEA+++V V Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 354 FVSLG-IRAGLVVACSIPLVLAMVFVFMEYSDITMQRISLGALIIALGLLVDDAMITVEV 412 ++ L +RA L+ ++P+VL F + ++ +++ +++A+GLLVDDA++ VE Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 413 MVTRLEMGETKEQAATF-AYTSTAFPMLTGTLVTVAGFVPIGLNASSAGEYTYTLFAVIA 471 + + + + AT + + ++ +V A F+P+ S G I Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 472 VALLVSWVVAVFFAPVLGVHILSSSKLKPHEAEPG----------RVGRAFEGGLLWCMR 521 A+ +S +VA+ P L +L + HE + G + + + Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 522 HRWLTIIGTVLLFALSIFSMRFVQNQFFPSSDRPEILVDLNLPQNASIEETRKVVDRLEA 581 ++ L+ A + + + F P D+ L + LP A+ E T+KV+D++ Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 582 RI-KDDPDLVHWSTYIGQGAIRFYLPLDQQLQNPYYAQLVIVSKGFEEREGMMQRLQKL- 639 K++ V + + Q QN A + K +EER G + + Sbjct: 596 YYLKNEKANVESVFTVNGFSF------SGQAQNAGMAF--VSLKPWEERNGDENSAEAVI 647 Query: 640 --LREEFVGI-GTNVQSLEMGPPVGRPIQYRVSGKDIDQVRKHAIELATLLD-------- 688 + E I V M P + +G D + + + + L Sbjct: 648 HRAKMELGKIRDGFVIPFNM-PAIVELG--TATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 689 SNEHIGEMIY---DWNEPGKVLRIEIAQDKARQLGLSSEDVANVMNSIVSGVPVTQINDN 745 + +H ++ + E ++E+ Q+KA+ LG+S D+ +++ + G V D Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 764 Query: 746 IYLVNVVARAEDSERGSPDTLQNLQIVTPSGASIPLLAFATVRYEQEQPLVWRRDRKPTI 805 + + +A+ R P+ + L + + +G +P AF T + P + R + P++ Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSM 824 Query: 806 TIKASVVGDIQPTDLVAELKPSIEGFASQLPVGYEVATGGTVEESSKAQGPIADVIPLML 865 I+ D +A +E AS+LP G G + + ++ + Sbjct: 825 EIQGEAAPGTSSGDAMAL----MENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISF 880 Query: 866 FLMATFLMIQLHSVQKLFLVVSVAPLGLIGVVLALVPTGTPMGFVAILGILALAGIIIRN 925 ++ L S V+ V PLG++GV+LA ++G+L G+ +N Sbjct: 881 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940 Query: 926 SVILVTQI-DEFEEQGYTPWDAVVEATNHRRRPILLTAAAASLGMIPIA------REVFW 978 ++++V D E++G +A + A R RPIL+T+ A LG++P+A Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 979 GPMAYAMIGGIISATLLTLLFLPALYVAWYKI 1010 + ++GG++SATLL + F+P +V + Sbjct: 1001 -AVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 91.4 bits (227), Expect = 8e-21 Identities = 87/528 (16%), Positives = 184/528 (34%), Gaps = 55/528 (10%) Query: 521 RHRWLTIIGTVLLFALSIFSMRFVQNQFFPSSDRPEILVDLNLPQNASIEET-RKVVDRL 579 R + ++L ++ + +P+ P + V N P A + V + Sbjct: 7 RRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQVI 65 Query: 580 EARIKDDPDLVHW---STYIGQGAIRFYLPLDQQLQNPYYAQLVIVSKGFEEREGMMQRL 636 E + +L++ S G I +P AQ+ + +K +Q Sbjct: 66 EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGT---DPDIAQVQVQNK--------LQLA 114 Query: 637 QKLLREEFVGIGTNVQSLEMGPPVGRPIQYRVSGKDIDQVRKHAIELATLLDSNEHIGEM 696 LL +E G +V+ + + Q +++ + SN + + Sbjct: 115 TPLLPQEVQQQGISVEKSSSSYLMV--AGFVSDNPGTTQ-----DDISDYVASN--VKDT 165 Query: 697 IYDWNEPGKV--------LRIEIAQDKARQLGLSSEDVANVMNSIVSGVPVTQINDNIYL 748 + N G V +RI + D + L+ DV N + + Q+ L Sbjct: 166 LSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPAL 225 Query: 749 VNVVARAEDSERG---SPDTLQNLQI-VTPSGASIPLLAFATVRY-EQEQPLVWRRDRKP 803 A + +P+ + + V G+ + L A V + ++ R + KP Sbjct: 226 PGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKP 285 Query: 804 TITIKASVVGDIQPTDLVAELKPSIEGFASQLPVGYEVA----TGGTVEES-SKAQGPIA 858 + + D +K + P G +V T V+ S + + Sbjct: 286 AAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLF 345 Query: 859 DVIPLMLFLMATFLMIQLHSVQKLFLVVSVAPLGLIGVVLALVPTGTPMGFVAILGILAL 918 + I L+ +M FL +++ + P+ L+G L G + + + G + L Sbjct: 346 EAIMLVFLVMYLFL----QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFG-MVL 400 Query: 919 A-GIIIRNSVILVTQI-DEFEEQGYTPWDAVVEATNHRRRPILLTAAAASLGMIPIA--- 973 A G+++ +++++V + E P +A ++ + + ++ A S IP+A Sbjct: 401 AIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFG 460 Query: 974 --REVFWGPMAYAMIGGIISATLLTLLFLPALYVAWYKIREPEDKTPR 1019 + + ++ + + L+ L+ PAL K E + Sbjct: 461 GSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK 508
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.050 Identities = 10/30 (33%), Positives = 14/30 (46%) Query: 33 LLGPSGCGKTTLLRIIAGLETPDDGSIVFH 62 L G G GK+TL+ + GL+ D Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 86.6 bits (214), Expect = 2e-22 Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 6/214 (2%) Query: 52 LALGLLVLVLHGAVAYWVSHQPTPELPVIPPKIPPMTIEFAAPAPPVAEPPPPAPVVQPP 111 + GLL +H + QP V P + P P P V P P P+ +PP Sbjct: 28 VVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPP 87 Query: 112 PPPPVVDELAAKPAPKPVPKPKPLPKPVAKPQPKPV-EAPPPTSVAAPAPPAPAPAPPAP 170 PVV E K + +P +P A P + A P + Sbjct: 88 KEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATS 147 Query: 171 APVTPASANAAYLKNPAPEYPQMAQRRGWEGTVLLRVEVLPSGKPGQIQIQKSSGRDALD 230 PVT ++ L P+YP AQ EG V ++ +V P G+ +QI + + + Sbjct: 148 KPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFE 207 Query: 231 AAALAAVKRWSFVPAKQGDVAQVGWVSVPIDFKL 264 A++RW + P K G + V I FK+ Sbjct: 208 REVKNAMRRWRYEPGKPG-----SGIVVNILFKI 236
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 4e-10 Identities = 32/165 (19%), Positives = 62/165 (37%), Gaps = 12/165 (7%) Query: 10 RRQQLIEATLQAVDQVGLGDASIALIARLAGVSNGIISHYFQDKNGLIAATMRHIMNMLN 69 RQ +++ L+ Q G+ S+ IA+ AGV+ G I +F+DK+ L + + + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 EGVIARRQALTDDSPRAHLKVIIEGNFDASQVNGPAMKTWLAFWASSMHQ----PSLHRL 125 E + QA P + L+ I+ +++ + + + + Sbjct: 72 E-LELEYQAKFPGDPLSVLREILIHVLESTVT-EERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 126 QRINDHRLYSNLCCQFRR------VLPLYHARKAARGLAALIDGL 164 QR Y + + + R+AA + I GL Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 46.5 bits (110), Expect = 1e-07 Identities = 35/204 (17%), Positives = 64/204 (31%), Gaps = 38/204 (18%) Query: 83 NARWSGIGRLSFPDSKQ---CIGTLVDSRDPSTPSSGPAYVITSGHCVDQRNGTIVQDKA 139 N ++ + + G +V G ++T+ H VD +G KA Sbjct: 84 NGHYAPVTYIQVEAPTGTFIASGVVV----------GKDTLLTNKHVVDATHGDPHALKA 133 Query: 140 LEGSI---SFNYFVDTAAKRKTFPFKRIVWSSMQGSDLALIELDARLQQVMA-EGIQPLL 195 +I ++ TA + + DLA+++ Q E ++P Sbjct: 134 FPSAINQDNYPNGGFTAEQITKYS---------GEGDLAIVKFSPNEQNKHIGEVVKPAT 184 Query: 196 LG--PSPATGSHVQVIGEPSRPDQGLRLSSCTEHAAEVVIEYPWVWRNARSNDCPGMREG 253 + ++ V G P S + ++ A D G Sbjct: 185 MSNNAETQVNQNITVTGYPGDKPVATMWES--------KGKITYLKGEAMQYDL-STTGG 235 Query: 254 ASGSPVIDSSNGQVVSVVNSGRKN 277 SGSPV + +V+ + G N Sbjct: 236 NSGSPVFN-EKNEVIGIHWGGVPN 258
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 61.1 bits (148), Expect = 4e-13 Identities = 26/163 (15%), Positives = 52/163 (31%), Gaps = 9/163 (5%) Query: 109 PPAAKPENPPAPAKSVVATQAPKTQKVEPKPKESKPQPKPEAKVPDFDSSQLSSQIASLE 168 PP P + + +E + KP+PKP KV + Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVE-------QPKRDVKP 120 Query: 169 AELSHEQQLYAKRPRIHRLNAASTLRDKGAWYKEEWRKKVERIGNLNYPEEARRQQLYGS 228 E P + A+ K + + R YP A+ ++ G Sbjct: 121 VESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRN-QPQYPARAQALRIEGQ 179 Query: 229 LRMMVSINRDGSLYEVLVLESSGQPVLDQAAQRIVRLAAPFAP 271 +++ + DG + V +L + + ++ + +R + P Sbjct: 180 VKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMR-RWRYEP 221
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 2e-16 Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 2/114 (1%) Query: 6 KVMVIDDSRTIRRTAQMLLGEAGCEVITASDGFDALAKIVDHKPRIIFVDVLMPRLDGYQ 65 ++V DD IR L AG +V S+ I ++ DV+MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 TCAIIKHNNTFKDTPVILLSSRDGLFDKARGRVVGSDQFLTKPFSKEELLDAIR 119 IK D PV+++S+++ + G+ +L KPF EL+ I Sbjct: 65 LLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.9 bits (192), Expect = 3e-20 Identities = 36/121 (29%), Positives = 55/121 (45%), Gaps = 4/121 (3%) Query: 2 ARILIVDDSPTEMYRLTEWLEKSGYGVLKADNGADGVALARQEKPDAVLMDIVMPGMNGF 61 A IL+ DD L + L ++GY V N A D V+ D+VMP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRQLSK-DPETSAIPVIVVTTKDQETDRIWAQRQGARDFLTKPVEEEALIAKLKEVLG 120 ++ K P+ +PV+V++ ++ I A +GA D+L KP + LI + L Sbjct: 64 DLLPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 A 121 Sbjct: 121 E 121
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.2 bits (177), Expect = 7e-15 Identities = 26/114 (22%), Positives = 54/114 (47%), Gaps = 2/114 (1%) Query: 1641 VMVVDDSVTVRKVTSRLLERHGMSVLTAKDGVDAMALLEEHRPDVLLLDIEMPRMDGFEV 1700 ++V DD +R V ++ L R G V + + D+++ D+ MP + F++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1701 ATRIRRDERLSQLPIIMITSRTGQKHRDRAMAIGVNEYLGKPYQESVLLQSIAH 1754 RI+ + LP+++++++ +A G +YL KP+ + L+ I Sbjct: 66 LPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.0 bits (215), Expect = 2e-22 Identities = 61/243 (25%), Positives = 99/243 (40%), Gaps = 14/243 (5%) Query: 5 VFITGATSGFGEATARRFADAGWKLVLTGRRKERLDALCQELSAKTEV-HGLVVDVRDRQ 63 FITGA G GEA AR A G + E+L+ + L A+ DVRD Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 64 AMEAAIASLPPSFDKLQGLVNNAGLALGVDAAQNCSLDDWETMVDTNIKGLMYTTRLLLP 123 A++ A + + LVN AG+ L + S ++WE N G+ +R + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 124 RLIAHGRGASILNVGSVAGNYPYPGANVYGGTKAFVGQFSLSLRCDLRGTGVRVSNIEPG 183 ++ R SI+ VGS P Y +KA F+ L +L +R + + PG Sbjct: 130 YMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 184 LCESEFSLV----------RFGGDQAKYDATYAGAEPIQPQDIAETIFWIL-NQPAHINI 232 E++ G + + +P DIA+ + +++ Q HI + Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 233 NSL 235 ++L Sbjct: 249 HNL 251
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.0 bits (145), Expect = 2e-13 Identities = 35/178 (19%), Positives = 63/178 (35%), Gaps = 10/178 (5%) Query: 3 PRAEQKLQTRQALLDAACLLMESGRGFGSISLREVAKAAGIVPTGFYRHFPDMDALGLAL 62 ++ +TRQ +LD A L +G S SL E+AKAAG+ Y HF D L + Sbjct: 4 KTKQEAQETRQHILDVALRLFSQ-QGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 63 VAEVDTTFRQTIR--LVRHNEFELGGITDASVRIF-LDVVVAHR---AQFLFLAREQYGG 116 ++ + + L + + + + V R + +F E G Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 117 SQPVRQAIARLRQDISNDLATDLARMPRWQHLDGAALAVMADLVVKTVFATLPELIDS 174 V+QA L + + + L +M + + L+++ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHC---IEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 45.2 bits (107), Expect = 2e-08 Identities = 28/143 (19%), Positives = 57/143 (39%), Gaps = 2/143 (1%) Query: 35 TEGYHADREKILRLLNESLATELVCVLRYKRHYFMASGIKASVAAAEFLEHANQEAEHAD 94 TE ++ + LN L+ + + R ++ G +F E + AE D Sbjct: 3 TENAKTNQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVD 62 Query: 95 KLAERIVQLGGEPDFNPDNLTKNSHAQ-YVAGNSLKEMVLEDLVAERIAIDSYREIIQYI 153 +AER++ +GG+P T+++ S EMV + + + +I Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLA 122 Query: 154 GD-KDPTTRRIFEDILAQEEEHA 175 + +D T +F ++ + E+ Sbjct: 123 EENQDNATADLFVGLIEEVEKQV 145
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.8 bits (67), Expect = 0.010 Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 7/85 (8%) Query: 58 GEQLLVIIEDICQRTGADKVNLIGHSQGA--LSARYAAAKRPDRVASVTSVA--GPNHGS 113 + L II+ G KV LIG+S GA + R +V P+ S Sbjct: 100 TQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFVLNEMPARYR-KNVLGAVLLSPSQSS 158 Query: 114 ELADHLER--TAPGDSVRGRLLKAV 136 + H+ T+ S R L V Sbjct: 159 DFEIHVSEMVTSDNQSARYLTLPEV 183
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 106 bits (267), Expect = 8e-34 Identities = 46/73 (63%), Positives = 59/73 (80%) Query: 33 QTLRDSVEKALHNYFAHLEGATVTDVYNLVLSEVEAPLLECVMNYVKGNQTKASEMLGLN 92 + LRDSV++AL NYFA L G V D+Y LVL+EVE PLL+ VM Y +GNQT+A+ M+G+N Sbjct: 25 KPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGIN 84 Query: 93 RGTLRKKLKQYDL 105 RGTLRKKLK+Y + Sbjct: 85 RGTLRKKLKKYGM 97
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.001 Identities = 33/239 (13%), Positives = 64/239 (26%), Gaps = 17/239 (7%) Query: 42 AKQLLEQNRAATAEGSAEAPPAVAEPVAPVATAAEPAAETPAPGDDNWSVTAEELDALDL 101 Q ++ T P+V +A E PAP + + ++ Sbjct: 988 RNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQE 1047 Query: 102 DQELARLERRSPGDRRGAAQSVLQARRDEQVG------DGHGDELFGTATDDDLTPAQVR 155 + + + E+ + + +A+ + + G E T T + A V Sbjct: 1048 SKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 156 EEAPVLVEQEPLDLEAAADERTEPTLGNADLDLDDEPPVRHQPPADELDEPLERLS---- 211 +E VE E + P ++ P R P + EP + + Sbjct: 1108 KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTAD 1167 Query: 212 -------VNDEPVPQKGLSALDDEVRSEPLSARDEEPDEQHGQRLEPSLAIKPERTRKE 263 + S + S + + P S R R+ Sbjct: 1168 TEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226
>PF05211#Neuraminyllactose-binding hemagglutinin Length = 260 Score = 32.3 bits (73), Expect = 0.006 Identities = 13/49 (26%), Positives = 23/49 (46%), Gaps = 5/49 (10%) Query: 700 RPRVVYLAACVSRVMGPAYADREQSSLLDKTRALLEKAGYQVVFPDNSD 748 RP Y S + Y ++ ++ K +L+ GY+V+ D+SD Sbjct: 62 RPAFQY-----SDNIAKEYENKFKNQTTLKVEQILQNQGYKVINVDSSD 105
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 43.7 bits (103), Expect = 7e-07 Identities = 39/147 (26%), Positives = 60/147 (40%), Gaps = 19/147 (12%) Query: 124 TLRTLVDLGV---------VPVINENDTVVTDEIRFGDNDTLAALVANLVEADLLVILTD 174 T++ LV+ GV VPVI E+ + E D D +A V AD+ +ILTD Sbjct: 178 TIKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTD 236 Query: 175 RDGMFDADPRNNPEAQLIYEARADDPSLDAVAGGTGGALGRGGMQTKLRAARLAARSGAH 234 +G + Q + E + ++ G G M K+ AA G Sbjct: 237 VNGAALY--YGTEKEQWLREVKVEELRKYYEEGH----FKAGSMGPKVLAAIRFIEWGGE 290 Query: 235 TIIIGGRIERVLDRLKAGERLGTLLSP 261 II +E+ ++ L G+ GT + P Sbjct: 291 RAII-AHLEKAVEAL-EGKT-GTQVLP 314
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 38.1 bits (88), Expect = 2e-04 Identities = 50/299 (16%), Positives = 107/299 (35%), Gaps = 42/299 (14%) Query: 466 IDISHIDPPALQALADRAALRDQKERLEKELK--QLKTQQAVALDRAASKAQTEALYQQV 523 +++H + A+QA +R L +E+ KE + + Q+A + + + E Sbjct: 113 TELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAE-----T 167 Query: 524 LDAQKALEDFRRTETLAAEEPEKLEQLGQ-LEAAQDELKRSSDAFTERVQQLSAKLQLVG 582 K E + +EE + +E + L AAQ E+ + +LS+ + Sbjct: 168 ERQLKLAEAEEKRLAALSEEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARD 227 Query: 583 RQIADLE----------AKQRTLEDALRRRQLLPADLPFGTPFMEA-------------- 618 ++ L AK + L++ +++ D PF EA Sbjct: 228 AEMKTLAGKRNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEK 287 Query: 619 ---IDDSMDNLLPLLNDYQDSWQALQRVDNQIEALYAQVRLKGVAKFDSEDDMERR---- 671 + S + + D +A+ +V N A A+V +++++ Sbjct: 288 QKQVTASETRINRINADITQIQKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKD 347 Query: 672 -LQLLINAYSHRTEEALTLAK--ARRAAVTDIARTLRNIRSDYDSLEHQLALFNREINK 727 + ++ Y TE+ A+ A + + N+ + E + N++ +K Sbjct: 348 AVDATVSFYQTLTEKYGEKYSKMAQELADKSKGKKIGNVNEALAAFEKYKDVLNKKFSK 406
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 7e-04 Identities = 20/89 (22%), Positives = 31/89 (34%), Gaps = 7/89 (7%) Query: 28 AAPSRPELLLPVAPVEDVGFEVRPAAPTPAPGATPTAPQARAERPKIEIPRPGSVPKPAA 87 A S + V G E + T TA + E+ K+E + VPK + Sbjct: 1071 EAKSNVKANTQTNEVAQSGSETKETQTTET---KETATVEKEEKAKVETEKTQEVPKVTS 1127 Query: 88 ----KPVEAEQEAPAPRPAPVPPPRFALQ 112 K ++E P PA P ++ Sbjct: 1128 QVSPKQEQSETVQPQAEPARENDPTVNIK 1156
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 8e-04 Identities = 15/59 (25%), Positives = 26/59 (44%) Query: 64 DEAHLLNITVKPENQGCGLGLRLLEHLMARAYQLNGRECFLEVRASNQSAYRLYERYGF 122 A + +I V + + G+G LL + A + + LE + N SA Y ++ F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 31.8 bits (72), Expect = 0.004 Identities = 12/51 (23%), Positives = 25/51 (49%), Gaps = 2/51 (3%) Query: 240 ARNLPLSEVLERLADYRGQRVLMLNEQATYQRVSGDFDLDHPAQSLERLAA 290 A+ L ++L V++ ++ +VSG F+ D+P L+ +A+ Sbjct: 40 AKGESLRDLLTDFGANYDATVVVSDKIND--KVSGQFEHDNPQDFLQHIAS 88
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 52/270 (19%), Positives = 97/270 (35%), Gaps = 14/270 (5%) Query: 38 LIQSVLPAIYPMLKANYGLSFAQIGLITLTFQITASLLQPWVGFFTDKRPTPNLLPLGTL 97 LI VLP + L + A G++ + + P +G +D+ +L + Sbjct: 23 LIMPVLPGLLRDLVHS-NDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLA 81 Query: 98 CTLVGIVMLAFVGSFPMILLASALVGIGSSTFHPETSRIARLASGGR----FGLAQSSFQ 153 V ++A ++ + + GI +T + IA + G FG + F Sbjct: 82 GAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFG 141 Query: 154 VGGNAGSALGPLLAAAIV-IPFGQTHVAWFGLAGLFFFAVTLMLRRWYKEHLNQAKARKA 212 G AG LG L+ PF A L GL F +L +K + R+A Sbjct: 142 FGMVAGPVLGGLMGGFSPHAPF----FAAAALNGLNFLTGCFLLPESHKGERRPLR-REA 196 Query: 213 VQATHGISRQRVILALVVLGLLVFSKYFYMSSFTSYFTFYLIEKFQLSVASSQLHLFLF- 271 + R + + L + F + + + ++F + + L F Sbjct: 197 LNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFG 256 Query: 272 -LGAVAAGTFFGGPIGDRIGRKAVIWFSIL 300 L ++A GP+ R+G + + ++ Sbjct: 257 ILHSLAQAMIT-GPVAARLGERRALMLGMI 285 Score = 30.2 bits (68), Expect = 0.017 Identities = 20/90 (22%), Positives = 36/90 (40%) Query: 281 FGGPIGDRIGRKAVIWFSILGVAPFTLALPYADLFWTTVLSVVIGFVLASAFSAIVVYAQ 340 G + DR GR+ V+ S+ G A + A W + ++ + + + Y Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA 121 Query: 341 ELVPGNVGMIAGIFFGLMFGFGGIGAALLG 370 ++ G+ F FGFG + +LG Sbjct: 122 DITDGDERARHFGFMSACFGFGMVAGPVLG 151
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.8 bits (95), Expect = 2e-06 Identities = 32/175 (18%), Positives = 56/175 (32%), Gaps = 23/175 (13%) Query: 7 RLDKNNAAVLLVDHQTGLLSLVRDIDP--DRFKNNVLALSDLAKYFKLPTILTT---SFE 61 D N A +L+ D Q + N+ L + +P + T S Sbjct: 25 VPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQN 84 Query: 62 TGPNGPLV----PELKEQFPDAPYIAR----PGNI-------NAWDNEDFVKAVKATGKK 106 L P L + I ++ +A+ + ++ ++ G+ Sbjct: 85 PDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRD 144 Query: 107 QLIIAGVVTEVCVAFPALSALEEGFDVFVVTDASGTFNELTRDSAWRRMEAAGAQ 161 QLII G+ + A A E F V DA F + + +E A + Sbjct: 145 QLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADF---SLEKHQMALEYAAGR 196
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.0 bits (135), Expect = 6e-11 Identities = 22/191 (11%), Positives = 59/191 (30%), Gaps = 8/191 (4%) Query: 2 KPLLSRSLTLVVVAVAIVLGWLAWTHYTQ-APWTRDARVRADVVTLAAEVSGRIVALPVR 60 ++ + I A + + + + V+ Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 61 DNQFVHKGDLLLRIDPARYELAVLHARRAVEVARAALGQSQANIVANQA-------LLKQ 113 + + V KGD+LL++ E L + ++ AR + Q + + L + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 114 RRSEEQRRGKLQSLSAISAEEWEKSKTDVAVAQADLLREQSSLGLAQANVQLAEATLEQA 173 + ++ L+++ E++ + + +L ++++ A + E Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 174 QLDLQRTEVLA 184 + L L Sbjct: 234 KSRLDDFSSLL 244 Score = 51.0 bits (122), Expect = 3e-09 Identities = 35/183 (19%), Positives = 68/183 (37%), Gaps = 17/183 (9%) Query: 72 LRIDPARYELAVLHARRAVEVARAALGQSQANI---------VANQALLKQRRSEEQRRG 122 L +D R E + AR + + +S+ + +A A+L+Q + Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266 Query: 123 KLQSLSAISAE---EWEKSKTDVAVAQADLLREQSSLGLAQANVQLAEAT--LEQAQLDL 177 +L+ + + E +K + + E L Q + T L + + Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD-KLRQTTDNIGLLTLELAKNEERQ 325 Query: 178 QRTEVLAPVNGHVTNL-LTRQGDFAQPGAALLALV-DSDSFHVSGYFEETKLPRIAVGSR 235 Q + + APV+ V L + +G L+ +V + D+ V+ + + I VG Sbjct: 326 QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQN 385 Query: 236 ARI 238 A I Sbjct: 386 AII 388
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 54.1 bits (130), Expect = 4e-10 Identities = 72/402 (17%), Positives = 148/402 (36%), Gaps = 54/402 (13%) Query: 25 QHMSPRIWLLALATFVTGMAENITVGILPALADGLQVPLGIAGQLTTVFSLSFALAAPFS 84 +H IWL L +F + + E + LP +A+ P + T F L+F++ Sbjct: 11 RHNQILIWLCIL-SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 85 PLLTTRFPLRRLLCITLALFALCNLAAALAPGYTALL-LARIGMATTSALTCLTCTLMAT 143 L+ + ++RLL + + ++ + + +LL +AR +A ++ Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 144 RLVPEALRGRAIGVIFMGICSSLVLGVPAGMLLCDMLGWRGVF----------------- 186 R +P+ RG+A G+I + +G G ++ + W + Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLL 189 Query: 187 ------------TGLSLLAIAV---LLMAWRGLPQLQSSERIALGSYLRHLRDS------ 225 G+ L+++ + +L ++ +++H+R Sbjct: 190 KKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 226 ----------RLVAAQGVSLLMIAGHFTVFAYLAPYARQVADIPVQWLAALFAIFGIAGV 275 V G+ +AG ++ Y+ Q++ + + + ++ + Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLS--TAEIGSVIIFPGTMSVI 307 Query: 276 SGGYVGGWMADRLGAGRCIALAPLLYLASLLVLPLSV-GTPWLFLPAMML-WGGLSWTTS 333 GY+GG + DR G + + S L + T W ++ GGLS+T + Sbjct: 308 IFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKT 367 Query: 334 PVVQSYLATRGPDTFPAGMSLNMSAMHLGVGLGSAIGGVVIT 375 + ++ AGMSL L G G AI G +++ Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>SECA#SecA protein signature. Length = 901 Score = 25.2 bits (55), Expect = 0.043 Identities = 9/19 (47%), Positives = 13/19 (68%) Query: 69 SYFRKAGVEHNVINASDHE 87 + KAG++HNV+NA H Sbjct: 467 NELTKAGIKHNVLNAKFHA 485
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 35.7 bits (82), Expect = 2e-04 Identities = 22/119 (18%), Positives = 36/119 (30%), Gaps = 1/119 (0%) Query: 406 QAGQVLEQAIKRYPDDLNLLYTRAMLAEKRNDLGQMEKDLRAILAREPENAMALNALGYT 465 + G + + D L LY+ A + K +A+ + ++ LG Sbjct: 20 KGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGAC 79 Query: 466 LADRTTRYSEAKALIDKAHQLTPDDPAVLDSLGWVAYRMGNLEEAERQLRRAFERFPDH 524 +Y A + +P + G L EAE L A E D Sbjct: 80 R-QAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADK 137
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 27.9 bits (62), Expect = 0.033 Identities = 17/108 (15%), Positives = 35/108 (32%), Gaps = 17/108 (15%) Query: 5 QELLRYSRQILLSQVDIDGQLRLKHGKALVIGLGGLGSPVALYLAAAGVGGLHLADFDTV 64 L Q L+ + + G+ +V+G + +GV L Sbjct: 153 AHLSHLVEQALV-------SMAEEQGETIVLGARITPEAYR--ESQSGVNPLQ------- 196 Query: 65 DLTNLQRQVIHDSDSVGTSKVDSAIKRLQAINPEISLVAHRQALDEDL 112 L + R + + + KR + + ++ ++AL DL Sbjct: 197 PLRDTYRDAVMGYQGI-YAIWSDLQKRFPNGDIDSVILFLQKALSADL 243
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.5 bits (66), Expect = 0.017 Identities = 22/84 (26%), Positives = 40/84 (47%), Gaps = 11/84 (13%) Query: 57 RLIARFYHEQGA-KALVLACNTATVAAVADLRELYPDWPLVGMEPAVKPAAAATRSGVVG 115 L+A F+ E GA A + +T +A+V+ LVG P +A V G Sbjct: 352 SLLAAFHKETGAIDASLTTISTV-LASVSSGISAAATTSLVG-----APVSALV-GAVTG 404 Query: 116 VLATTGTLQSAKFAALLDRFANDV 139 ++ +G L+++K A+ + A+ + Sbjct: 405 II--SGILEASK-QAMFEHVASKM 425
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 37.7 bits (87), Expect = 2e-05 Identities = 25/115 (21%), Positives = 45/115 (39%), Gaps = 9/115 (7%) Query: 6 WVTGASHGVGLALVGQLLASGHQVAASGRDSQELDTLGRQHGARL---------LRLPAP 56 ++TGA+ G+G A+ L + G +AA + ++L+ + A +R A Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAA 71 Query: 57 LPEASQRLLAKWGALDSLIINAGTCDYLPDAVADGEVFEQIISSNLLATQECLAG 111 + E + R+ + G +D L+ AG E +E S N Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 43.2 bits (102), Expect = 6e-07 Identities = 54/307 (17%), Positives = 95/307 (30%), Gaps = 71/307 (23%) Query: 1 MHILLTGGTGLIGQHLCQVWRQQGHRLTVW---------SRRPEQVAKICGTGVRGI--- 48 M L+TG G IG H+ + + GH++ S + ++ + G + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 49 ----ARLEDIADDDEVDALVNL---AGAPIA-DRPWTAARRNLLWASRVTLTEQLLAWLE 100 + D+ + + + + P A NL T +L Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNL------TGFLNILEGCR 114 Query: 101 RRERRPQVLISGSAVGWYGDGGERELTEASP---PVKEDFASQLCIAWEETAQRAEAL-G 156 + + + S S+V YG + + PV A++ A E A L G Sbjct: 115 HNKIQHLLYASSSSV--YGLNRKMPFSTDDSVDHPVSLYAATKK--ANELMAHTYSHLYG 170 Query: 157 IRVVLVRTGLVLAADG-------GFLSRLRLPYKLGLGGPL---GDGRQWMPWVHIDD-- 204 + +R V G F + G + G+ + +IDD Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAML------EGKSIDVYNYGKMKRDFTYIDDIA 224 Query: 205 --QIGLIDFLLQHN-----EASGPYNACAP---------EPVRNREFAKRLGRTLHRPA- 247 I L D + + E P + AP PV ++ + L L A Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 248 --FMPMP 252 +P+ Sbjct: 285 KNMLPLQ 291
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.3 bits (128), Expect = 1e-09 Identities = 28/138 (20%), Positives = 49/138 (35%), Gaps = 7/138 (5%) Query: 10 LIVDDFTDFRTSTRSMLRELGVRDVDTADSGEQALRMCGQKRYDFILQDFHLGDGKKNGQ 69 L+ DD RT L G DV + R D ++ D + D N Sbjct: 7 LVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDE--NAF 63 Query: 70 QVLEDLILDKLISHECVFIMVTAESSQSIVLSAIEHEPDAYLTKPFNRVGLAQRLEK-LT 128 +L + K + ++++A+++ + A E YL KPF+ L + + L Sbjct: 64 DLLPRI---KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 129 QRKTLLKPILQALDRSRP 146 + K + P Sbjct: 121 EPKRRPSKLEDDSQDGMP 138
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 3e-05 Identities = 17/102 (16%), Positives = 37/102 (36%), Gaps = 26/102 (25%) Query: 136 NAIRYA------GHALLISIEEEGEQLVISVNDDGAGYPQRMLERQHDYVQGIDSQSGST 189 N I++ G +L+ ++ + + V + G+ + + ST Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL--------------ALKNTKEST 311 Query: 190 GLGLYFA-ARIAALHERNGVRGRIEIANGGTLGGGLFRLYLP 230 G GL R+ L+ G +I+++ G + +P Sbjct: 312 GTGLQNVRERLQMLY---GTEAQIKLSE--KQGKVNAMVLIP 348
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 101 bits (254), Expect = 1e-27 Identities = 38/121 (31%), Positives = 64/121 (52%), Gaps = 11/121 (9%) Query: 115 MPGNITFATDSANISPSFYSPLNNLANSFKQFN--QNTIEVVGFTDSTGSRQHNMDLSQR 172 + ++ F + A + P + L+ L + + ++ V+G+TD GS +N LS+R Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER 276 Query: 173 RAQAVSTYLTSQGVDSSRVSVRGMGPDQPIASNADANGR---------AQNRRVEVNLKP 223 RAQ+V YL S+G+ + ++S RGMG P+ N N + A +RRVE+ +K Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336 Query: 224 I 224 I Sbjct: 337 I 337
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 30.3 bits (68), Expect = 0.003 Identities = 22/70 (31%), Positives = 34/70 (48%), Gaps = 3/70 (4%) Query: 4 AANKAVSIDYTLTNDAGEVIDSS-AGGAPLVYLHGAANIIPGLEKALEGKQAGDELTVAI 62 + V+++YT T G V DS+ G P + + +IPG +AL+ AG V + Sbjct: 142 GKSDTVTVEYTGTLIDGTVFDSTEKAGKPATF--QVSQVIPGWTEALQLMPAGSTWEVFV 199 Query: 63 EPEDAYGEYS 72 + AYG S Sbjct: 200 PADLAYGPRS 209
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 2e-09 Identities = 25/155 (16%), Positives = 61/155 (39%), Gaps = 8/155 (5%) Query: 79 YQLAVDQAKALVASRKATWEMRKVNAKRRADLDNLVISKENRDDASNIASSALADYQHAQ 138 + +A + K+ E + + A + ++++ +++ + + Sbjct: 257 QENKYVEAVNELRVYKSQLEQIE-SEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 139 AQLAAAELNLKRTQIVATVDGYVTNLNIH-KGDYARTGEAVMAVV-DEQSFWVYGFFEET 196 +LA E + + I A V V L +H +G T E +M +V ++ + V + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNK 375 Query: 197 KLPHVKVGDVAELQMMS-----GERIKGHVESIAR 226 + + VG A +++ + + G V++I Sbjct: 376 DIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Score = 51.0 bits (122), Expect = 2e-09 Identities = 21/117 (17%), Positives = 45/117 (38%), Gaps = 10/117 (8%) Query: 46 VAADVPGYVVDVPVKDNQRVKKGDVLIRIDPEHYQLAVDQAKALVASRKATWEMRKVNAK 105 + V ++ VK+ + V+KGDVL+++ + + ++ + + + R Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE-QTRYQILS 157 Query: 106 RRADLDNLVISKENRD---------DASNIASSALADYQHAQAQLAAAELNLKRTQI 153 R +L+ L K + + + S + Q Q ELNL + + Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 1e-11 Identities = 75/414 (18%), Positives = 151/414 (36%), Gaps = 31/414 (7%) Query: 33 LFGVLLAVLCAGLNEAVTKISLSDIRGAMGIGADEGAWLLAVYAAASVSAMAFAPWLATT 92 L + + + LNE V +SL DI W+ + A L+ Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 93 FSLRRFTMSAVGVFAVLGLIQPFAPNLHSLMLL-RVLQGFASGALPPMLMSVALRFLPPG 151 ++R + + + +I + SL+++ R +QG + A P ++M V R++P Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 152 IKVYGLACYALTATFGPNLGTPLAGLWTEYVGWQWAFWQIILPSLLAIACVGWGLPQDPL 211 + G +G + G+ Y+ W + ++P + I L + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL---LIPMITIIT--VPFLMKLLK 190 Query: 212 RLERFRQ-LDWRGVLLGLPAISCIVLGLSLGDRWGWFDSPLICWLLGVGVLLLVLFMFNE 270 + R + D +G++L I +L + + L V VL ++F+ + Sbjct: 191 KEVRIKGHFDIKGIILMSVGIVFFMLFTTS-YSISF---------LIVSVLSFLIFVKHI 240 Query: 271 WSEPLPFFQLRMLTRRNLSFALVTLAGVLVVLSGVGSIPSAYLAQIQGYRPAQTSPLMML 330 PF + ++ + ++G S+ + + A+ +++ Sbjct: 241 RKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIF 300 Query: 331 VA-MPQLIALPLTAALCNIRAVDCRWVLAMGLAMLAASCVGSSLL--TSQWIRGDFYPFY 387 M +I + L + R +VL +G+ L+ S + +S L T+ W F Sbjct: 301 PGTMSVIIFGYIGGILVDRRGP--LYVLNIGVTFLSVSFLTASFLLETTSW----FMTII 354 Query: 388 LLQVFGQPMAVLPLLMLS-TNGMTPQEGPFASAWFNTVKGLSA----VIAGGLL 436 ++ V G ++ ++ + QE + N LS I GGLL Sbjct: 355 IVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 132 bits (333), Expect = 9e-37 Identities = 65/367 (17%), Positives = 114/367 (31%), Gaps = 83/367 (22%) Query: 47 VVAPKVAGFIKEVLVEDNQQVKAGQLLATIDPRDYQAALDAAQAQLLVARAQSLDARATL 106 + P +KE++V++ + V+ G +L + +A Q+ LL AR + + L Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI-L 156 Query: 107 ERQASLIAQAEAAVKAAQAEAAFADHEVTRYSRLAEQGAGTVQNAQ-QARSGVDQARARL 165 R L E + ++ EV R + L ++ T QN + Q +D+ RA Sbjct: 157 SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAER 216 Query: 166 ANTQAALVATRKQVDIL-------------------------------GAQVASADGQLK 194 A + + ++ QL+ Sbjct: 217 LTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE 276 Query: 195 RAEAGLEKARL------------------------------------DLSYTRITAPVDG 218 + E+ + A+ + I APV Sbjct: 277 QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSV 336 Query: 219 MVGE-RALRVGAYVNPGARLLSVVPLARAYIV-GNFQETQLTHVQPGQPVSISVDTFSGE 276 V + + G V L+ +VP V Q + + GQ I V+ F Sbjct: 337 KVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 277 K---LHGRVESIAPATGVTFAAVKPDNATGNFTKVVQRIPVKIVFDDGQPLLERLRVGMS 333 + L G+V++I D G V+ I + + + L GM+ Sbjct: 397 RYGYLVGKVKNINLDA-------IEDQRLGLVFNVIISIEENCLSTGNKNI--PLSSGMA 447 Query: 334 VEAVIDT 340 V A I T Sbjct: 448 VTAEIKT 454
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.1 bits (210), Expect = 1e-21 Identities = 58/200 (29%), Positives = 86/200 (43%), Gaps = 14/200 (7%) Query: 4 VLITGCSSGIGRALADAFRDAGHEVWA----TARKAKDVEQLAAAGFNARQ--LDVNDAD 57 ITG + GIG A+A G + A + K V L A +A DV D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 58 AL----ARLAEELQSLDILINNAGYGAMGPLLDGGVEAMRQQFETNVFALVGVTRALFPL 113 A+ AR+ E+ +DIL+N AG G + E F N + +R++ Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 114 LRRSR-GLVVNIGSVSGVLVTPFAGAYCASKAAVHGLSDALRLELAPFGIRVMEVQPGAI 172 + R G +V +GS + AY +SKAA + L LELA + IR V PG+ Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 173 ASQFASN---AQQQAEQVLA 189 + + + AEQV+ Sbjct: 191 ETDMQWSLWADENGAEQVIK 210
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 24.3 bits (52), Expect = 0.041 Identities = 11/36 (30%), Positives = 16/36 (44%) Query: 12 NNNNNNNNNNNNNNNNKGRIRSQNNQPQFAPCQTPE 47 N N NNNNNN I ++ N+ + + E Sbjct: 873 NAKLGNFNNNNNNGLKNEPIYAKVNKKKAGQAASLE 908
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 811 bits (2096), Expect = 0.0 Identities = 336/1026 (32%), Positives = 550/1026 (53%), Gaps = 32/1026 (3%) Query: 7 FIRRPVLACVVSLLILLLGLQAWNKLQIRQYPQMENALITVTTAYPGANAETIQGYITQP 66 FIRRP+ A V+++++++ G A +L + QYP + ++V+ YPGA+A+T+Q +TQ Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LQQSLASADGIDYMTSVSRQNFS-VISVYARIGADTDRLFTQLLAKANEVRNKLPQDSED 125 ++Q++ D + YM+S S S I++ + G D D Q+ K LPQ+ + Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 126 PVLSKEAADASALMYISFYSN--EMSNPQITDYLSRVIQPKLATLPGMAEAEILGNQVFA 183 +S E + +S LM F S+ + I+DY++ ++ L+ L G+ + ++ G Q +A Sbjct: 125 QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ-YA 183 Query: 184 MRIWIDPVKLAGFGLSAVDVTNAVRRYNFLSAAGEV------KGQYVVTSINATTELKSA 237 MRIW+D L + L+ VDV N ++ N AAG++ GQ + SI A T K+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 238 EAFAALPVKTSGD-SRVLLGDVARVEMGAENYDTVSSFDGTPSVYIGIKATPAANPLEVI 296 E F + ++ + D S V L DVARVE+G ENY+ ++ +G P+ +GIK AN L+ Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 297 KEVRRIMPQLEEALPASLKVSIAYDATLFIQASIDEVIKTLGEAVLIVIVVVFLFLGALR 356 K ++ + +L+ P +KV YD T F+Q SI EV+KTL EA+++V +V++LFL +R Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 357 SVVIPVVTIPLSMIGVLFFMQMMGYSLNLLTLLAMVLAIGLVVDDAIVVVENIHRHIEEG 416 + +IP + +P+ ++G + GYS+N LT+ MVLAIGL+VDDAIVVVEN+ R + E Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 417 KS-PFDAALEGAREIALPVVSMTITLAAVYAPIGFLTGLTGALFKEFALTLAGAVVISGI 475 K P +A + +I +V + + L+AV+ P+ F G TGA++++F++T+ A+ +S + Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 476 VALTLSPMMCALLLR-----HEQNPSGLAHRLDLIFDALKVRYQRLLHGTLNSRPVVLVF 530 VAL L+P +CA LL+ H +N G + FD Y + L S L+ Sbjct: 484 VALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLI 543 Query: 531 AVLILCLIPALLMFTRNELAPEEDQGVIFMMSSSPQTANLDYLNAYTDQFTPIF--KRFP 588 LI+ + L + + PEEDQGV M P A + DQ T + Sbjct: 544 YALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKA 603 Query: 589 EYYSSFQINGF----NGVQSGIGGFLLKPWNER---ERTQMQLLPLVQAELEQIGGLQIF 641 S F +NGF +G+ LKPW ER E + ++ + EL +I + Sbjct: 604 NVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVI 663 Query: 642 GFNLP--SLPGTGEGLPFQLVINTAGDYPALLEVAQRVKERA-QASGKFAFLDIDLAFDK 698 FN+P GT G F+L+ + AL + ++ A Q + + D Sbjct: 664 PFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDT 723 Query: 699 PEVVIDIDRAKAAQMGVSMDTLGSTLATLLGEAEINRFTLEGRSYKVIAQVERPYRANPG 758 + +++D+ KA +GVS+ + T++T LG +N F GR K+ Q + +R P Sbjct: 724 AQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPE 783 Query: 759 WLNNYYVKNEQGQLLPLATLITLNDRARPRQLNQFQQLNSAIIQGVPL--VSMGEALETV 816 ++ YV++ G+++P + T + +L ++ L S IQG S G+A+ + Sbjct: 784 DVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALM 843 Query: 817 RAIAREEAPEGFSLDYAGAARQFVQEGSALWVTFGLALAIIFLVLAAQFESFRDPLVILV 876 +A + P G D+ G + Q G+ ++ ++FL LAA +ES+ P+ +++ Sbjct: 844 ENLA-SKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVML 902 Query: 877 TVPLSICGALLPLFLGVSSMNIYTQVGLVTLIGLITKHGILIVEFANQLRDERGLGVREA 936 VPL I G LL L ++Y VGL+T IGL K+ ILIVEFA L ++ G GV EA Sbjct: 903 VVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEA 962 Query: 937 IEEAAAIRLRPVLMTTAAMVFGMVPLILASGAGAVSRFDIGMVIATGMSVGTLFTLFVLP 996 A +RLRP+LMT+ A + G++PL +++GAG+ ++ +G+ + GM TL +F +P Sbjct: 963 TLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVP 1022 Query: 997 CIYSVL 1002 + V+ Sbjct: 1023 VFFVVI 1028 Score = 108 bits (272), Expect = 4e-26 Identities = 85/513 (16%), Positives = 168/513 (32%), Gaps = 42/513 (8%) Query: 6 PFIRRPVLACVVSLLILLLGLQAWNKLQIRQYPQM-ENALITVTTAYPGANAETIQGYIT 64 + ++ LI+ + + +L P+ + +T+ GA E Q + Sbjct: 532 KILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLD 591 Query: 65 QPLQQSLAS-ADGIDYMTSVSRQNFSVISVYARIG------------------ADTDRLF 105 Q L + ++ + +V+ +FS + A + A R Sbjct: 592 QVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 106 TQLLAKANEVRNKLPQDSEDPVLSKEAADASALMYISFYSNEMSNPQITDYLSRVIQPKL 165 +L K + L L+ + ++ L Q Sbjct: 652 MEL-GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPA 710 Query: 166 ATLPGMAEAEILGNQVFAMRIWIDPVKLAGFGLSAVDVTNAVRRYNFLSAAGEVKGQYVV 225 + + Q ++ +D K G+S D+ + + + + V Sbjct: 711 SLVSVRPNGLEDTAQ---FKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRV 767 Query: 226 TSINATTE---LKSAEAFAALPVKTSGDSRVLLGDVARVEMGAENYDTVSSFDGTPSVYI 282 + + E L V+++ V + ++G PS+ I Sbjct: 768 KKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWV-YGSPRLERYNGLPSMEI 826 Query: 283 GIKATPAANPLEVIKEVRRIMPQLEEALPASLKVSIAYDATLFIQASIDEVIKTLGEAVL 342 +A P + +M L LPA + + + V Sbjct: 827 QGEAAPGT----SSGDAMALMENLASKLPAGIGYDWTGMSYQERLSG-----NQAPALVA 877 Query: 343 IVIVVVFLFLGAL-RSVVIPVV---TIPLSMIGVLFFMQMMGYSLNLLTLLAMVLAIGLV 398 I VVVFL L AL S IPV +PL ++GVL + ++ ++ ++ IGL Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLS 937 Query: 399 VDDAIVVVENI-HRHIEEGKSPFDAALEGAREIALPVVSMTITLAAVYAPIGFLTGLTGA 457 +AI++VE +EGK +A L R P++ ++ P+ G Sbjct: 938 AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG 997 Query: 458 LFKEFALTLAGAVVISGIVALTLSPMMCALLLR 490 + + G +V + ++A+ P+ ++ R Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 3e-05 Identities = 25/125 (20%), Positives = 45/125 (36%), Gaps = 4/125 (3%) Query: 78 GTVKSLHFESGQQVKAGQLLLQLDSDQETALLGTAQADLGLAKVDFGRGSQLVGDSAISR 137 VK + + G+ V+ G +LL+L + A Q+ L A+++ R Q++ S Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTR-YQILSRSIELN 163 Query: 138 GEFDRLTAQYRRNQAVVEQLKA---SLAKKSISAPFSGTIGIRQVDVGAYLASGTVIATL 194 + Q V E+ SL K+ S + TV+A + Sbjct: 164 KLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARI 223 Query: 195 QDLSS 199 + Sbjct: 224 NRYEN 228
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 30.2 bits (68), Expect = 0.011 Identities = 14/72 (19%), Positives = 27/72 (37%), Gaps = 9/72 (12%) Query: 103 PDKKNLVGRQVEQLVNGE---------QAVTAESLGKASVVVRGLSAYEYILFDSKPDIA 153 D+ N + Q L NG QA+ + ++ K V L+ + L D+ + Sbjct: 13 SDQYNFIKSQAYILANGHATANDRGVIQALKSLAIEKIIHVFENLTDEQKELIDTVLTVQ 72 Query: 154 SAEQKARYCPLL 165 + E + + Sbjct: 73 NREDAESFLLKI 84
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1310 bits (3393), Expect = 0.0 Identities = 667/1033 (64%), Positives = 825/1033 (79%), Gaps = 4/1033 (0%) Query: 1 MSKFFIDRPIFAWVIALVIMLVGALSILKLPINQYPSIAPPAIAISVTYPGASAQTVQDT 60 M+ FFI RPIFAWV+A+++M+ GAL+IL+LP+ QYP+IAPPA+++S YPGA AQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VVQVIEQQLNGIDNLRYVSSESNSDGSMTITATFEQGTNSDTAQVQVQNKLNLATPLLPQ 120 V QVIEQ +NGIDNL Y+SS S+S GS+TIT TF+ GT+ D AQVQVQNKL LATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGIRVTKAVKNFLLVIGLVSEDGSMSKDDLANYIVSNMQDPISRTAGVGDFQVFGA 180 EVQQQGI V K+ ++L+V G VS++ ++DD+++Y+ SN++D +SR GVGD Q+FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDPAKLNKFQLTPVDVRTAVAAQNVQVSSGQLGGLPALPGTQLNATIIGKTRL 240 QYAMRIWLD LNK++LTPVDV + QN Q+++GQLGG PALPG QLNA+II +TR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTAEQFEKILLKVNNDGSQVRLGDVATVGLGGENYAISAQYNGKPASGLAVKLATGANAL 300 + E+F K+ L+VN+DGS VRL DVA V LGGENY + A+ NGKPA+GL +KLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKALRTTISDLEPFFPPGVKAVFPYDTTPVVTESISGVIHTLIEAVVLVFLVMYLFLQ 360 DTAKA++ +++L+PFFP G+K ++PYDTTP V SI V+ TL EA++LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATIITTMTVPVVLLGTFGILAAAGFSINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RAT+I T+ VPVVLLGTF ILAA G+SINTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEGLPPKEATKRSMEQIQGALVGIALVLSAVLLPMAFFGGSTGVIYRQFSITIVSAMGL 480 E+ LPPKEAT++SM QIQGALVGIA+VLSAV +PMAFFGGSTG IYRQFSITIVSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALIFTPALCATMLKPLKKGEHHVAKRGFFGWFNRNFDRSVAGYERSIGTILRNKIP 540 SVLVALI TPALCAT+LKP+ EHH K GFFGWFN FD SV Y S+G IL + Sbjct: 481 SVLVALILTPALCATLLKPVSA-EHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 FLLAYALIVVGMIWLFARIPTAFLPEEDQGVLFAQVQTPAGSSAERTQVVVDQMREYLLD 600 +LL YALIV GM+ LF R+P++FLPEEDQGV +Q PAG++ ERTQ V+DQ+ +Y L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEADTVASVFTVNGFNFAGRGQSSGMAFIMLKPWGERS-KENSVFALAQRAQMHFFSFRD 659 E V SVFTVNGF+F+G+ Q++GMAF+ LKPW ER+ ENS A+ RA+M RD Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 660 AMVFAFAPPAVLELGNATGFDVFLQDRAGVGHAKLMEARNQFLAKAAQSKI-LSAVRPNG 718 V F PA++ELG ATGFD L D+AG+GH L +ARNQ L AAQ L +VRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 719 LNDEPQYQLTIDDERASALGVTIADINNTLSIALGGSYVNDFIDRGRVKKVYIQGEPNSR 778 L D Q++L +D E+A ALGV+++DIN T+S ALGG+YVNDFIDRGRVKK+Y+Q + R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 779 MSPEDLQKWYVRNGKGEMVPFSSFAKGEWSYGSPKLSRYNGVEAVEILGTPAPGYSTGEA 838 M PED+ K YVR+ GEMVPFS+F W YGSP+L RYNG+ ++EI G APG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 839 MAEVERIAGELPTGIGYSWTGMSYEEKLSGSQMPALFALSVLFVFLCLAALYESWSIPIA 898 MA +E +A +LP GIGY WTGMSY+E+LSG+Q PAL A+S + VFLCLAALYESWSIP++ Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 899 VVLVVPLGIIGALLATSLRGLSNDVYFLVGLLTTIGLAAKNAILIVEFAKELHE-QGRSL 957 V+LVVPLGI+G LLA +L NDVYF+VGLLTTIGL+AKNAILIVEFAK+L E +G+ + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 958 YDAAIEACRMRLRPIIMTSLAFILGVVPLTIASGAGAGSQHAIGTGVIGGMISATVLAIF 1017 +A + A RMRLRPI+MTSLAFILGV+PL I++GAG+G+Q+A+G GV+GGM+SAT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1018 WVPLFFVAVSSLF 1030 +VP+FFV + F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 38/226 (16%), Positives = 81/226 (35%), Gaps = 23/226 (10%) Query: 73 ILKRLFKEG----TDVKEGQQLY---QIDPAVYEATLANAQANLQATRSLAERYKQLIDE 125 L + V E + Y + VY++ L ++ + + + + QL Sbjct: 239 DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN 298 Query: 126 QAVSKQEYDDANAKRLQAEASLKSAQIDLRYTKVLAPISGRIGRSSV-TEGALVNNGQTN 184 + + K L + + + + AP+S ++ + V TEG +V +T Sbjct: 299 EILDK--LRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET- 355 Query: 185 AMATIQQLDPIYVDVTQSTAELLKLRRDL------ESGQLQKAGENAAQVQLVLEDGSLF 238 M + + D + V ++ + E+ + G +V+ + D Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIED 415 Query: 239 KQQGRLEFSEVAVDETTGSVTLRAIFPNPDHTLLPGMFVHARLKAG 284 ++ G + ++++E S + I L GM V A +K G Sbjct: 416 QRLGLVFNVIISIEENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 41.4 bits (97), Expect = 4e-06 Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 2/96 (2%) Query: 61 RVAEVRPQVNGIILKRLFKEGTDVKEGQQLYQIDPAVYEATLANAQANLQATRSLAERYK 120 R E++P N I+ + + KEG V++G L ++ EA Q++L R RY+ Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 121 QLIDEQAVSKQEYDDANAKR--LQAEASLKSAQIDL 154 L ++K + L Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 142 bits (360), Expect = 8e-45 Identities = 79/209 (37%), Positives = 121/209 (57%) Query: 1 MVRRTKEEAQETRAQIIEAAEKAFYKRGVARTTLADIAELAGVTRGAIYWHFSNKAELVQ 60 M R+TK+EAQETR I++ A + F ++GV+ T+L +IA+ AGVTRGAIYWHF +K++L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 ALLDSLHETHDHLARASESEDELDPLGCMRKLLLQVFNELVLDARTRRINEILHHKCEFT 120 + + L +++ DPL +R++L+ V V + R R + EI+ HKCEF Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 DDMCEIRQQRQGAVLDCHQSIALALGNAVRRGQLPGELDIDRAAVAMFAYVDGLIGRWLL 180 +M ++Q ++ L+ + I L + + LP +L RAA+ M Y+ GL+ WL Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 LPDSFDLLADVEKWVDTGLDMLRLSPGLR 209 P SFDL + +V L+M L P LR Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLR 209
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 135 bits (340), Expect = 7e-37 Identities = 92/412 (22%), Positives = 171/412 (41%), Gaps = 25/412 (6%) Query: 13 VLTALMLAIFLGALDQTIVAVSMPAISAQFNDVG-LLAWVISGYMVAMTIAVPIYGKLGD 71 +L L + F L++ ++ VS+P I+ FN WV + +M+ +I +YGKL D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 72 LYGRRRMILTGTALFTLASVACGLAQDM-PQLVLARVLQGIGAGGMVSVSQAIIGDFVPP 130 G +R++L G + SV + L++AR +QG GA ++ ++ ++P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 131 RERGRYQGYFSSMYALASVAGPVLGGWLTEYLSWRWVFWINLPLGLVALWVIHRALDGLS 190 RG+ G S+ A+ GP +GG + Y+ W ++ I + + +++ Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKE-- 192 Query: 191 VKRREARVDYLGAVLMILGLGSLLLGITLVGQGHAWLSSQVLALLGCALLGLLAFIAHER 250 R + D G +LM +G+ +L T +S +L L F+ H R Sbjct: 193 -VRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVS----------VLSFLIFVKHIR 241 Query: 251 RCREPLLPLSLFGNR---VAVLCWCVIFFASFQSISLTMLMPLRYQGITGAGADSAALHL 307 + +P + L N + VLC +IF +S+ M ++ A S + Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI--I 299 Query: 308 LPLAMGLPIGAFTGGRMTSRTGRFKPQILTGALLMPLAIAAMALTPPQSGLLGAVFMLLT 367 P M + I + GG + R G + G + ++ + + + ++ Sbjct: 300 FPGTMSVIIFGYIGGILVDRRGPLYVLNI-GVTFLSVSFLTASFLLETTSWFMTIIIVFV 358 Query: 368 GIACGLQFPTSLVGT--QSAVDSRDIGVATSTTNLFRSLGGAMGVACMSSLL 417 GL F +++ T S++ ++ G S N L G+A + LL Sbjct: 359 --LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 32.1 bits (73), Expect = 0.001 Identities = 26/122 (21%), Positives = 39/122 (31%), Gaps = 29/122 (23%) Query: 3 KIAIIGATGRAGSQLLEEALRRGHSVVAI-----ARDPG------SLQGRDGVTVKALDA 51 K + GA G G + + L GH VV I D L + G +D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 52 KDSAALQA--AVAGCDAVLSAAH-----FSTLEPGA-----------IIEPVKRAGVKRL 93 D + A + V + H +S P A I+E + ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 94 LV 95 L Sbjct: 122 LY 123
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.6 bits (66), Expect = 0.019 Identities = 15/71 (21%), Positives = 22/71 (30%), Gaps = 9/71 (12%) Query: 263 QDQAPPAVIAKPAPVARPAVAPPVPPRIVALPPRVGRSNAAPATRAMPAEDDAQLLASIA 322 Q PP + +P P P PP P + + P + P + Q Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEA-----PVVIEKPKPKPKPKPKPVKKVEQP----K 115 Query: 323 RHANAGDSAQA 333 R +S A Sbjct: 116 RDVKPVESRPA 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.5 bits (183), Expect = 5e-16 Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 2/112 (1%) Query: 640 RKRILVVDDSLTVRELQRKLLGNRGYDVAVAVDGMDGWNALRSDDFDLLITDIDMPRMDG 699 ILV DD +R + + L GYDV + + W + + D DL++TD+ MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 700 IELVTLVRRDSRLQSLPVMVVSYKDREEDRRRGLDAGADYYLAKASFHDDAL 751 +L+ ++ LPV+V+S ++ + + GA YL K + + Sbjct: 63 FDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 50.6 bits (121), Expect = 4e-09 Identities = 28/172 (16%), Positives = 60/172 (34%), Gaps = 9/172 (5%) Query: 2 RIAIVNDMPMAVEALRRALAFEPAHQVIWVAGNGAEAVRLCAEQTPDLILMDLIMPVMDG 61 I + +D L +AL+ + V + N A R A DL++ D++MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 VEATRRIMAETPCAIVIVTVDRKQNVHRVFEAMGHGALDVVDTPALGAGDAREAAAPLLR 121 + RI P V+V + +A GA D + P ++ Sbjct: 63 FDLLPRIKKARPDLPVLVMSA-QNTFMTAIKASEKGAYDYLPKPF-----DLTELIGIIG 116 Query: 122 KILNIGWLIGQQRPSAARTVAAPLRETSQRRALVAIGSSAGGPAALEVLLKG 173 + L + ++ + ++ + + + + L +++ G Sbjct: 117 RALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARL-MQTDLTLMITG 167
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.3 bits (154), Expect = 3e-13 Identities = 28/118 (23%), Positives = 51/118 (43%), Gaps = 3/118 (2%) Query: 15 SAAMVLLVDDQAMIGEAVRRGLAHEENIDFHFCADPHQAVAQAMRIKPTVILQDLIMPGL 74 + A +L+ DD A I + + L+ D ++ +++ D++MP Sbjct: 2 TGATILVADDDAAIRTVLNQALS-RAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 75 DGLTLVREYRNNPATQDIPIIVLSTKEDPLVKSAAFAAGANDYLVKLPDTIELVARIR 132 + L+ + A D+P++V+S + + A GA DYL K D EL+ I Sbjct: 61 NAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 167 bits (425), Expect = 4e-54 Identities = 86/236 (36%), Positives = 133/236 (56%), Gaps = 7/236 (2%) Query: 1 MKQHRLAAAVALVGLVLAGCDAQTSSVELKTPAQKASYGIGLNMGKSLAQEGMDDLDSKA 60 MK + AA+ +GL ++ A T + L T K SY IG ++GK+ +G+D ++ Sbjct: 1 MKMKLVTAAI--MGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGID-INPDV 57 Query: 61 VAQGIEDAVGKKEQRIKDEELVEAFTALQK----RAEERLAKASEEAAAAGKKFLEENGK 116 +A+G++D + + + +E++ + + QK + K +EE A G FL N Sbjct: 58 LAKGMQDGMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKS 117 Query: 117 KPGVITTASGLQYEVVKKADGPQPKPTDVVTVHYEGKLTDGKVFDSSVERGSPIDLPVSG 176 KPG++ SGLQY+++ G +P +D VTV Y G L DG VFDS+ + G P VS Sbjct: 118 KPGIVVLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQ 177 Query: 177 VIPGWVEGLQLMHVGEKYKLYIPAELAYGAQSPSPLIPANSVLVFDLELIAIKDPA 232 VIPGW E LQLM G +++++PA+LAYG +S I N L+F + LI++K A Sbjct: 178 VIPGWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKAA 233
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 30.1 bits (67), Expect = 0.023 Identities = 20/56 (35%), Positives = 32/56 (57%), Gaps = 6/56 (10%) Query: 564 RLARMAAPADDQLLLIGRRHVRSNNSWMHNYHRLVKGKP----RHQLLMHPDDLQR 615 RL +MA A Q+ IG+ N++ + +L++ +P + QL +HPDDLQR Sbjct: 119 RLMQMALEAARQV--IGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQR 172
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 30.6 bits (69), Expect = 0.002 Identities = 19/92 (20%), Positives = 39/92 (42%), Gaps = 8/92 (8%) Query: 56 DKLIKRILFLEGIPN--VQDLGKLM------IGEHTKEMLDCDLKLEKKAHADLKAAIAH 107 D + +R+L + G P V++ + EM+ + K+ ++ K I Sbjct: 62 DTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGL 121 Query: 108 CETAGDFGSRDVLEDILEDQEEHIDWLETQLG 139 E D + D+ ++E+ E+ + L + LG Sbjct: 122 AEENQDNATADLFVGLIEEVEKQVWMLSSYLG 153
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.7 bits (66), Expect = 0.011 Identities = 11/36 (30%), Positives = 20/36 (55%), Gaps = 4/36 (11%) Query: 3 EDLYEDDQDSQVSSGSRHPMAERF----RGYLPVVV 34 +DL E++++S S G + P A RF + P ++ Sbjct: 118 QDLSEEEKNSMNSRGEKVPFASRFVFEKKRETPKLI 153
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 94.8 bits (235), Expect = 1e-24 Identities = 64/249 (25%), Positives = 128/249 (51%), Gaps = 6/249 (2%) Query: 38 FECRLIQPIDGFGSGEFVRRAGEQPT--FQLLSESNVLGAGSATLLAAAAPWQPGRGDIN 95 EC+L+ PI FG F RA ++ F+L + + +L++ PW+PG Sbjct: 44 LECQLVHPIPSFGDAVFSSRASKKINLDFELKMRRPMGETRNVSLISMPPPWRPGEHADR 103 Query: 96 LGAVHMARTGVLFTSSQGQASRLINGLLDGR--STVVRNYRGEGGRPMEVHVMPVSFAKA 153 + + + + Q A +++ L GR + ++++ R +EV + V F Sbjct: 104 ITNLKFFKQFDGYVGGQ-TAWGILSELEKGRYPTFSYQDWQSRDQR-IEVALSSVLFQSK 161 Query: 154 YSDYQLCAAKLLPMNYDQIRQTQVGFPGGGIELDSSARARLDVLLDYLKADPTVNHIELN 213 Y+ + C A LL +++ I T + + G +L +++ RL + DY++ + ++ + + Sbjct: 162 YNAFSDCIANLLKYSFEDIAFTILHYERQGDQLTKASKKRLAQIADYVRHNQDIDLVLVA 221 Query: 214 GHSDNSGNRLTNRDTSRRRALAVAEYLKAHGVPEEQITVRFHGERYPLAKNNTAANRARN 273 ++D++ + ++ S RRA ++ Y ++ G+PE++I V+ +G+R P+A N T + +N Sbjct: 222 TYTDSTDGKSESQSLSERRAESLRTYFESLGLPEDRIQVQGYGKRRPIADNGTPIGKDKN 281 Query: 274 RRVNIQLER 282 RRV I L R Sbjct: 282 RRVVISLGR 290
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 26.2 bits (57), Expect = 0.016 Identities = 14/62 (22%), Positives = 19/62 (30%), Gaps = 3/62 (4%) Query: 19 IGLLAWSLMAHPPIHTPLPMQAGGVPHQPDPDTPQPPEPGEHPPMEPGEPTLPDEPPPAP 78 IG + L A+ L +P P QP PP E P P Sbjct: 549 IGTYRYRLAANGNGQWSLVGAKAPPAPKPAP---QPGPQPPQPPQPQPEAPAPQPPAGRE 605 Query: 79 VA 80 ++ Sbjct: 606 LS 607
>SECA#SecA protein signature. Length = 901 Score = 57.2 bits (138), Expect = 9e-14 Identities = 18/48 (37%), Positives = 22/48 (45%), Gaps = 1/48 (2%) Query: 19 HHDHDHGHVHGPHCNHGHQEPVRNALKDVGRNDPCPCGSEKKFKKCHG 66 H + + VGRNDPCPCGS KK+K+CHG Sbjct: 852 AQMQQLSHQDDDS-AAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHG 898
>SECA#SecA protein signature. Length = 901 Score = 49.1 bits (117), Expect = 1e-09 Identities = 15/26 (57%), Positives = 18/26 (69%) Query: 129 TVALKAGRNDPCPCASGQKFKKCCAS 154 T K GRNDPCPC SG+K+K+C Sbjct: 874 TGERKVGRNDPCPCGSGKKYKQCHGR 899 Score = 28.7 bits (64), Expect = 0.011 Identities = 8/14 (57%), Positives = 8/14 (57%) Query: 6 CPCGSGNLLDACCG 19 CPCGSG C G Sbjct: 885 CPCGSGKKYKQCHG 898
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 119 bits (300), Expect = 2e-34 Identities = 60/181 (33%), Positives = 84/181 (46%), Gaps = 13/181 (7%) Query: 60 GLAAGYCWAHGDGDEDGDGV-PDSRDKCPGTPRGVQVDANGCPPEPAPVVEEVVVQKEEV 118 Y W + GD G PD+ G PAP V K Sbjct: 157 ATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH-F 215 Query: 119 IVIRDVHFEFNSASLTLKDKERLDKVASRLKQ-EAPSARLSVTGHTDSVGSDSYNQKLSE 177 + DV F FN A+L + + LD++ S+L + + V G+TD +GSD+YNQ LSE Sbjct: 216 TLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSE 275 Query: 178 RRAQSVTNYLVESGVPRSSFISVGGAGETQPVADNATADGR---------AMNRRTEIKI 228 RRAQSV +YL+ G+P IS G GE+ PV N + + A +RR EI++ Sbjct: 276 RRAQSVVDYLISKGIPADK-ISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 229 Q 229 + Sbjct: 335 K 335
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 120 bits (302), Expect = 1e-34 Identities = 55/138 (39%), Positives = 75/138 (54%), Gaps = 11/138 (7%) Query: 113 PASAPQPEPTATPEVITLDDQGQVLFAFDSAELTQGAQQRLQGLLPKL--NDPSVTSVKV 170 P AP P P + + VLF F+ A L Q L L +L DP SV V Sbjct: 198 PVVAPAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVV 257 Query: 171 IGFTDSVGSDSYNQRLSERRASGVAEYLISQGLAPNKVTSQGRGESEPVADNDTDEGRSR 230 +G+TD +GSD+YNQ LSERRA V +YLIS+G+ +K++++G GES PV N D + R Sbjct: 258 LGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQR 317 Query: 231 ---------NRRVELHLN 239 +RRVE+ + Sbjct: 318 AALIDCLAPDRRVEIEVK 335
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.9 bits (106), Expect = 1e-08 Identities = 17/67 (25%), Positives = 30/67 (44%), Gaps = 2/67 (2%) Query: 70 VHYVFHRSTWGRNDFCYLEDLYVCPSARGRMIGKQLIEFVQDQARQQQCDRLYWHTQETN 129 + + RS W N + +ED+ V R + +G L+ + A++ L TQ+ N Sbjct: 77 IGRIKIRSNW--NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDIN 134 Query: 130 RTAQRLY 136 +A Y Sbjct: 135 ISACHFY 141
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 31/127 (24%), Positives = 62/127 (48%), Gaps = 2/127 (1%) Query: 7 RILIVEDDQRLAELTAEYLQANGFEVAVEGDGGRAARRIIDSQPDLVILDLMLPGEDGLS 66 IL+ +DD + + + L G++V + + R I DLV+ D+++P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 ICRRVRGQYAG-PILMLTARSDELDQIQGLDLGADDYVCKPVRPRVLLARI-NALLRRSE 124 + R++ P+L+++A++ + I+ + GA DY+ KP L+ I AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 125 APERRQE 131 P + ++ Sbjct: 125 RPSKLED 131
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 4e-05 Identities = 21/107 (19%), Positives = 35/107 (32%), Gaps = 25/107 (23%) Query: 429 LQNLVRNAMRHA------ESQVRLSYQIGQQRCRIDVEDDGPGIPEGVWHRIFTPFTRLD 482 +Q LV N ++H ++ L ++VE+ G + Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE---------- 309 Query: 483 DSRTRASGGHGLGLSIVR-RIIYWHGGRALVGHSEQLGGACFSLSWP 528 G GL VR R+ +G A + SE+ G + P Sbjct: 310 --------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 106 bits (265), Expect = 3e-30 Identities = 69/224 (30%), Positives = 109/224 (48%), Gaps = 14/224 (6%) Query: 11 LQHHWPLPRPVPGAVLVSCAFDPGRLAADDFLRAGIEQTASLQRSVAKRQAEYLAGRVCA 70 L H+PLP G L FD D L + L+ + KR+AE+LAGR+ A Sbjct: 2 LTSHFPLP--FAGHRLHIVDFDASSFREHDLLW--LPHHDRLRSAGRKRKAEHLAGRIAA 57 Query: 71 REALKRLDGRDYVPATHEDRSPIWPADIRGSITHGQGWAAAVVAADGHCRGLGLDQETLL 130 AL+ + G VP + R P+WP + GSI+H A AV++ + +G+D E ++ Sbjct: 58 VHALREV-GVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISR----QRIGIDIEKIM 112 Query: 131 SEERAERLAGEILTPAELERLDRSQQA--LAVTLTFSLKESLFKTLYPLTKQRFYFEHAE 188 S+ A LA I+ E + L S LA+TL FS KES++K + F A+ Sbjct: 113 SQHTATELAPSIIDSDERQILQASLLPFPLALTLAFSAKESVYKA-FSDRVTLPGFNSAK 171 Query: 189 LLAWSADGHARLRLLTDLSAEWHHGVELDGQFCLQDGHLLSLIS 232 + + +A H L LL +A + ++ +D +++L+S Sbjct: 172 VTSLTA-THISLHLLPAFAAT-MAERTVRTEWFQRDNSVITLVS 213
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 33.4 bits (76), Expect = 4e-04 Identities = 38/167 (22%), Positives = 63/167 (37%), Gaps = 18/167 (10%) Query: 10 AMAVCAAGLTSVAQA---DDNF---ASLTYGQTSD--KVRKSGLLQRNTDGLNADGIIGK 61 A+AV AG +VAQA D+ + A L + Q D + +G N G A G Sbjct: 7 AIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGAFGGYQV 66 Query: 62 DSTWGARLGKINDQGRYYVTYDNVSGDHS--GVKLRQENLLGSYDLFLPVGDTTKLFGGG 119 + G +G + GR +G + GV+L Y P+ D ++ Sbjct: 67 NPYVGFEMG-YDWLGRMPYKGSVENGAYKAQGVQL---TAKLGY----PITDDLDIYTRL 118 Query: 120 SLGMTKLTQDSPGARRDTDYGYAVGLQAGVIQEVTDNTSVELGYRYL 166 + + S ++ D G + GV +T + L Y++ Sbjct: 119 GGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWT 165
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 3e-20 Identities = 31/120 (25%), Positives = 56/120 (46%), Gaps = 1/120 (0%) Query: 2 KLLVVEDEALLRHHLFTRLGEGGHVVQAVANAEEALYQAEQYNHDLAVIDLGLPGMSGLD 61 +LV +D+A +R L L G+ V+ +NA + DL V D+ +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRQLRSLGQTFPILILTARGNWQDKVEGLAAGADDYVVKPFQFEE-LEARLNALLRRSS 120 L+ +++ P+L+++A+ + ++ GA DY+ KPF E + AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.018 Identities = 33/163 (20%), Positives = 57/163 (34%), Gaps = 35/163 (21%) Query: 292 RASLRKSG--LVKYQVELKPLLDSLCSTLAKVYRDKRVEVSLDIPAL---ARVPMEQGAL 346 R SLR S V EL + L LA + + R++ I +VP + Sbjct: 205 RYSLRYSNARQVSLADELTVVDSYL--QLASIQFEDRLQFENQINPAIMDVQVP----PM 258 Query: 347 LELLGNLLENAYRLCL------GQVRVSLRQSPGLLELCVEDDGPGVPPDQRERILERGE 400 L + L+EN + + G++ + + G + L VE+ G + +E Sbjct: 259 L--VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------- 309 Query: 401 RLDRQHPGQGIGLAVVKD-IIDSYDAELSLG-DSALGGAAFRI 441 G GL V++ + Y E + G + Sbjct: 310 -------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 2e-16 Identities = 28/117 (23%), Positives = 46/117 (39%), Gaps = 5/117 (4%) Query: 668 PKILCVDDNPANLLLVQTLLEGMGAEVLAVDNGYGAVQAVQDEPFDLVLMDVQMPGMDGR 727 IL DD+ A ++ L G +V N + + DLV+ DV MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 728 ACTEQIRQWESSQSGPPLPIVALTAHAMANEKRALLHSGMDDYLTKPISERQLAQVV 784 +I++ P LP++ ++A G DYL KP +L ++ Sbjct: 64 DLLPRIKKA-----RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 6e-22 Identities = 42/138 (30%), Positives = 59/138 (42%), Gaps = 4/138 (2%) Query: 8 ATNILAIEDDPVLGAYLHDELQRGGFQVTWCRDALEGLEAAGRQVFDLVLMDILLPGLNG 67 IL +DD + L+ L R G+ V +A DLV+ D+++P N Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 68 LDALVSLR-RRSATPVILMSALGAEADRISGFERGADDYLPKPFSFAELRVRIEAILRRV 126 D L ++ R PV++MSA I E+GA DYLPKPF EL I L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE- 121 Query: 127 AFERRARAPREADAGQLH 144 +R + E D+ Sbjct: 122 --PKRRPSKLEDDSQDGM 137
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 11/45 (24%), Positives = 23/45 (51%) Query: 347 ENMLRNAIRHSPEVGVVRLSGWREGGYWRIDLEDEGGGVAEEDLE 391 EN +++ I P+ G + L G ++ G +++E+ G + E Sbjct: 265 ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE 309
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.016 Identities = 16/97 (16%), Positives = 33/97 (34%), Gaps = 8/97 (8%) Query: 7 DQLLKAGLVNQKQVSQTNKAEKKQKRLEHKGQVEVDDSQQRLAKQA-MAEKAKKDQELNR 65 D+ T + K+ + D+ + A+ +A++AK + + N Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 66 QVQEKAEQKA-------RAAQIKQLIEATRLPKLTTE 95 Q E A+ + + +E K+ TE Sbjct: 1081 QTNEVAQSGSETKETQTTETKETATVEKEEKAKVETE 1117 Score = 28.5 bits (63), Expect = 0.017 Identities = 17/78 (21%), Positives = 30/78 (38%), Gaps = 6/78 (7%) Query: 17 QKQVSQTNKAEKKQKRLEHKGQVEVDDSQQRLAKQAMAEKAKKDQELNRQ------VQEK 70 + + + T + E+K K K Q + Q KQ +E + E R+ ++E Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 71 AEQKARAAQIKQLIEATR 88 Q A +Q + T Sbjct: 1159 QSQTNTTADTEQPAKETS 1176
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 3e-04 Identities = 14/47 (29%), Positives = 19/47 (40%) Query: 108 PVLPPSGARERPLEPEPEAKKPEPAPAPPPAPAEPEVRPTRIITSPV 154 P P E P E +KP+P P P P P + +P R + Sbjct: 76 PEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122 Score = 31.1 bits (70), Expect = 0.003 Identities = 17/82 (20%), Positives = 24/82 (29%) Query: 96 IEDIAAAIAIDLPVLPPSGARERPLEPEPEAKKPEPAPAPPPAPAEPEVRPTRIITSPVR 155 +E A PV+ P E EP EA P P P P V+ V+ Sbjct: 60 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVK 119 Query: 156 GGQQIYAQGGDLVVTGSVSPGA 177 + A + + Sbjct: 120 PVESRPASPFENTAPARPTSST 141
>PF07520#Virulence protein SrfB Length = 1041 Score = 28.4 bits (63), Expect = 0.042 Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 5/69 (7%) Query: 244 LEDGSGYRLVVHPP----LADFPGETEEADCLRINQWVEGVLRECPEQYLWAHRRFKS-R 298 E +RLV P E+ + + + WV L+E + A R +S Sbjct: 173 SEKPREFRLVSDPGAMSWFLQRLEADEDGNAVDLQLWVSDWLKEMFLDFKRAERPGRSIS 232 Query: 299 PEGEPRLYD 307 E P +++ Sbjct: 233 EENLPHMFE 241
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 188 bits (478), Expect = 6e-61 Identities = 64/206 (31%), Positives = 86/206 (41%), Gaps = 10/206 (4%) Query: 90 ALNIYDPLESLNRRIYHFNYR-FDQWVFLPVVDGYRYVTPSFVRTGVSNFFNNLGDVPNL 148 DPLE NR +Y+FN+ D ++ PV +R P R G+SNF NL + + Sbjct: 25 QQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVM 84 Query: 149 FNSVLQLKPKRSAEITARLMFNTIIGVGGLWDPATKMGLPRQ---SEDFGQTLGFYGVPD 205 N LQ P + R NTI+G+GG D A Q FG TLG YGV Sbjct: 85 VNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGY 144 Query: 206 GPYLMLPILGPSNLRDTTGLVVDYVGEKEINYLNVPDTASDHPELTVLRAVDKRYTTNFR 265 GPY+ LP G LRD G + D + +++L P + L ++ R Sbjct: 145 GPYVQLPFYGSFTLRDDGGDMADAL-YPVLSWLTWPMSVG----KWTLEGIETRAQLLDS 199 Query: 266 YG-QTNSPFEYEKLRYVYTQARKLQI 290 G S Y +R Y Q Sbjct: 200 DGLLRQSSDPYIMVREAYFQRHDFIA 225
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.7 bits (64), Expect = 0.044 Identities = 19/103 (18%), Positives = 40/103 (38%), Gaps = 16/103 (15%) Query: 114 INEYLKKLFYQAGYHVVQLSSPTSWDFMSAASRFATPGVTSEDAKDLYRVMQAVRAQQAR 173 +++ + + Q G+ VV W + + P + +D ++ +A+ Sbjct: 66 LDKAVGGILQQQGWPVV------GWSSLKYYWKQKDP---KDVTQDTLAIIDKYQAEFGT 116 Query: 174 LPVSEYYLTGYSLGA--LDAAFVSKLDETRQSFNFKRVLLLNP 214 V L GYS GA + +++ + N +LL+P Sbjct: 117 QKVI---LIGYSFGAEVIPFVL-NEMPARYRK-NVLGAVLLSP 154
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 2e-15 Identities = 25/105 (23%), Positives = 49/105 (46%), Gaps = 1/105 (0%) Query: 3 KVLVVDDHPFIRTSVCMQLRLDNLEVVGQADNGIDAVVLARERKPDVVILDLLLPGLDGL 62 +LV DD IRT + L +V N D+V+ D+++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EVISRIRMMGSPVKVVVLTSQLTENFSLRCMKAGASGFVSKTEDL 107 +++ RI+ + V+V+++Q T +++ + GA ++ K DL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDL 108
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 37.5 bits (87), Expect = 3e-05 Identities = 11/52 (21%), Positives = 23/52 (44%) Query: 2 LGLQLTRMGHRVTVAVNGQQALQVCLKTPFDVVFTGLSLPGLDSCRLVRALR 53 L L+R G+ V + N + D+V T + +P ++ L+ ++ Sbjct: 19 LNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIK 70
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 4e-19 Identities = 53/186 (28%), Positives = 90/186 (48%), Gaps = 7/186 (3%) Query: 6 MITGAGSGLGREIALRWARDGWRLALADVNEAGLRETLELVRSIGGDGFIQ---RCDVRD 62 ITGA G+G +A A G +A D N L ++V S+ + DVRD Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL---EKVVSSLKAEARHAEAFPADVRD 68 Query: 63 YSQLTALAQACEEKLGGIDVIVNNAGVASGGFFADLSLEDWDWQIAVNLMGVVKGCKAFL 122 + + + E ++G ID++VN AGV G LS E+W+ +VN GV ++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 123 P-MLERSRGRIINIASMAALMQGPGMSNYNVAKAGVLALSESLLVELRQVEVAVHVVCPS 181 M++R G I+ + S A + M+ Y +KA + ++ L +EL + + ++V P Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 182 FFQTNL 187 +T++ Sbjct: 189 STETDM 194
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 0.003 Identities = 15/53 (28%), Positives = 18/53 (33%) Query: 194 LAVDPHCTRPGVGEVLVRHLIEHFMSRGLACLDLSVLHDNRQAKRLYKKLGFR 246 +AV + GVG L+ IE L L N A Y K F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 395 bits (1016), Expect = e-136 Identities = 244/492 (49%), Positives = 316/492 (64%), Gaps = 27/492 (5%) Query: 2 SKVKENAIVSAVSALQPKGPSSSFGLIDSFAHQYDRG-GANINGKKSFTADQAADHILRD 60 + + + SS++ + F +DRG G +NGK S++ DQAA I R+ Sbjct: 7 LRQDDAQHALS------ANTSSAYNSVYDFLRYHDRGDGLTVNGKTSYSIDQAAAQITRE 60 Query: 61 GAAWKDLNKDG-TISLTYTFLTKAPSDFYSRGLGSFSQFSDLQKQQAKLSMQSWADVAKV 119 +W N G + +LT+ FL S G F +F+ Q +QAKLS+QSW+DVA + Sbjct: 61 NVSWNGTNVFGKSANLTFKFLQSVSS--IPSGDTGFVKFNAEQIEQAKLSLQSWSDVANL 118 Query: 120 TFTEAASGGDGHMTFGNFSASNGG------AAFAYLPFDGPGSHKGESWYLINSGYQVNI 173 TFTE ++TFGN++ G A+AY P G G SWY N Sbjct: 119 TFTEVTGNKSANITFGNYTRDASGNLDYGTQAYAYYP--GNYQGAGSSWYNYNQSN--IR 174 Query: 174 NPGTGNYGRQTLTHEIGHVLGLSHPGDYNAGEGNPTYRDADYAQDTRGYSVMSYWSESNN 233 NPG+ YGRQT THEIGH LGL+HPG+YNAGEG+P+Y DA YA+D+ +S+MSYW E+ Sbjct: 175 NPGSEEYGRQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENET 234 Query: 234 GQNFIKGGGQYYASAPLMDDILAIQKLYGANYATRASDTTYGFNSTADRDFYSATSASSK 293 G ++ +Y AP++DDI AIQ+LYGAN TR D+ YGFNS DRDFY+AT +S Sbjct: 235 GADYNG----HYGGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKA 290 Query: 294 LVFSVWDGGGNDTFDFSGFTQNQKINLNEASFSDVGGMVGNVSIAKGVTIENAIGGSGND 353 L+FSVWD GG DTFDFSG++ NQ+INLNE SFSDVGG+ GNVSIA GVTIENAIGGSGND Sbjct: 291 LIFSVWDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGND 350 Query: 354 LLIGNALANVLKGGAGNDIIYGGGGADQLWGGSGSDTFVFAAVSDSTKAAPDRIMDFTSG 413 +L+GN+ N+L+GGAGND++YGG GAD L+GG+G DTFV+ + DST AA D I DF G Sbjct: 351 ILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKG 410 Query: 414 VDKIDLSAISAFAVNKLPLQFVNAFTGHAGEALLTYDQATNLGSLAIDFTGNSSADFLVT 473 +DKIDL SAF + FTG E +L +D A ++ +L + G+SS DFLV Sbjct: 411 IDKIDL---SAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVR 467 Query: 474 TVGQAAVTDIVV 485 VGQAA +DI+V Sbjct: 468 IVGQAAQSDIIV 479
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 87.0 bits (215), Expect = 2e-25 Identities = 35/125 (28%), Positives = 57/125 (45%), Gaps = 4/125 (3%) Query: 1 MKANLRTIALAA-IPMVSMTEVVMASSLLLPNAAQLAGRWQLYPEQQQAQACDLRLGATE 59 M I + VS MASS ++P+ AQ+AG+ + + Sbjct: 1 MPRFSHLIGCVWQVLFVSAGAQAMASSFVVPSTAQMAGQLGI---EATGSGVCAGPAEQA 57 Query: 60 GEIEGDLECAKGLIGLRPGSWLVTPDTLALVGGDGSSVVHFNREGAQRYAWTTPDGKQLV 119 + GD+ CA+ +G +P SW TPD + L+ +G+ + H NR+ Y TP G + Sbjct: 58 NALAGDVACAEQWLGDKPVSWSPTPDGIWLMNAEGTGITHLNRQKEGEYTGRTPSGADVT 117 Query: 120 LERLD 124 L+R + Sbjct: 118 LQRTN 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 2e-24 Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 6/123 (4%) Query: 6 KILIVDDFSTMRRIIKNLLRDLGFTNVKEADDGNTALPMLTSEHFDFLVTDWNMPGMTGI 65 IL+ DD + +R ++ L G+ V+ + T + + D +VTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 DLLRAVRADERLKHLPVLMVTAEAKREQIIEAAQAGVNGYVVKPF---TAVALKEKIEKI 122 DLL ++ + LPVL+++A+ I+A++ G Y+ KPF + + + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 123 FER 125 +R Sbjct: 122 PKR 124
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 7e-06 Identities = 11/72 (15%), Positives = 30/72 (41%), Gaps = 10/72 (13%) Query: 446 ETDLDKNLVEALADPLV--HLVRNAVDHGVEMPDEREASGKSRMGRVVLSAEQEGDHILL 503 E ++ +++ P++ LV N + HG+ + G+++L ++ + L Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTL 294 Query: 504 SISDDGKGMDPS 515 + + G + Sbjct: 295 EVENTGSLALKN 306
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.3 bits (141), Expect = 2e-11 Identities = 30/147 (20%), Positives = 52/147 (35%), Gaps = 7/147 (4%) Query: 2 AVKVLVVDDSGFFRRRVSEILSADPTIQVVGTATNGKEAIDQALALKPDVITMDYEMPMM 61 +LV DD R +++ LS V +N A D++ D MP Sbjct: 3 GATILVADDDAAIRTVLNQALS-RAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVRHIMQRCP-TPVLMFSSLTHEGARVTLDALDAGAVDYLPKNF--EDISRNPEKV 118 + + I + P PVL+ S+ + A + GA DYLPK F ++ + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAI--KASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 119 KQLLCEKVHTISRSNRRFSAYSSPAPA 145 + + ++ + A Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAA 145
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 67.6 bits (165), Expect = 4e-15 Identities = 33/122 (27%), Positives = 52/122 (42%), Gaps = 16/122 (13%) Query: 134 LNSSLLFASADAMPSDVAFEIVEKVAKILR---PFANPVHVEGFTDNLPIRTAQYPTNWE 190 L S +LF A ++++ L P V V G+TD I + Y N Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--NQG 272 Query: 191 LSSARAASIVRLLAMEGVNPARMASVGYGEYQPVASNDTADGRAR---------NRRVVL 241 LS RA S+V L +G+ ++++ G GE PV N + + R +RRV + Sbjct: 273 LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332 Query: 242 VI 243 + Sbjct: 333 EV 334
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.017 Identities = 21/102 (20%), Positives = 28/102 (27%), Gaps = 9/102 (8%) Query: 55 EQARDAQRQVIPTPPAARPFAEPQAKILPTVLPPAAPVVE---------PVVAVVETEVV 105 A Q + PP EP+ + +P A V+E P + Sbjct: 56 APADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPK 115 Query: 106 ADASIPVLSETQAIEPVAPLVELNVPAAPAAPTPPASVDGRP 147 D E AP + A A P SV P Sbjct: 116 RDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGP 157
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 31.0 bits (70), Expect = 0.019 Identities = 12/19 (63%), Positives = 14/19 (73%) Query: 725 SDILRYRALKRLGGLYIDA 743 SDILR L + GGL+IDA Sbjct: 135 SDILRLFLLCKYGGLWIDA 153
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 69.0 bits (169), Expect = 3e-17 Identities = 19/77 (24%), Positives = 30/77 (38%), Gaps = 3/77 (3%) Query: 9 AIALSYDGQ--QAPTLSAKGDDELAEAILAIAREHEVPIYENPELVR-LLARLELGEQIP 65 AI + Y P ++ K D + + IA E VPI + L R L + IP Sbjct: 268 AIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRIPLARALYWDALVDHYIP 327 Query: 66 EALYLTIAEIIAFAWQL 82 AE++ + + Sbjct: 328 AEQIEATAEVLRWLERQ 344
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.036 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 32 MLQIAGPNGSGKTSLLRLLAGL 53 + + G G GK++L+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 2e-14 Identities = 34/136 (25%), Positives = 63/136 (46%), Gaps = 5/136 (3%) Query: 1 MQGAPLSLLLVEDSSMDAELTLLCLERSGLQVQSRLVFDHVGVEHALREDSYDLILCDCV 60 M GA ++L+ +D + + L R+G V R+ + + + DL++ D V Sbjct: 1 MTGA--TILVADDDAAIRTVLNQALSRAGYDV--RITSNAATLWRWIAAGDGDLVVTDVV 56 Query: 61 LPGSSGTDVLAIVQRLAPDIPFIFLSGIYGEEHAVEMIRLGATDYVLKK-NLPLLPKAVH 119 +P + D+L +++ PD+P + +S A++ GA DY+ K +L L + Sbjct: 57 MPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 120 RALTEVHERQRRRRAE 135 RAL E R + + Sbjct: 117 RALAEPKRRPSKLEDD 132 Score = 67.2 bits (164), Expect = 1e-13 Identities = 28/120 (23%), Positives = 50/120 (41%), Gaps = 5/120 (4%) Query: 680 RRSVLLVDDDHLVREMMSDVLLRHGYQVRQAHSSEQALPLLNDE-IDVLLTDFAMPEFNG 738 ++L+ DDD +R +++ L R GY VR ++ + D+++TD MP+ N Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 739 AQLALAARQRFPDLPVVFLTGYAEL----QGLELPGSLVIQKPVSEQALAQALAELLENR 794 L ++ PDLPV+ ++ + E + KP L + L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.4 bits (123), Expect = 2e-10 Identities = 21/123 (17%), Positives = 53/123 (43%), Gaps = 13/123 (10%) Query: 5 ILLVEDNPRDLELTLLALERSQLANEVIVLRDGAEALDYLLRRNTYAERDDGNPAVLLLD 64 IL+ +D+ + AL R +V + + A ++ G+ +++ D Sbjct: 6 ILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWI---------AAGDGDLVVTD 54 Query: 65 LKLPKVDGLEVLKQVRDTAELRSIPTVMLTSSREEPDLLRAYELGVNAYVVKPVEFKEFV 124 + +P + ++L +++ +P +++++ ++A E G Y+ KP + E + Sbjct: 55 VVMPDENAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112 Query: 125 AAI 127 I Sbjct: 113 GII 115
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.002 Identities = 26/144 (18%), Positives = 49/144 (34%), Gaps = 30/144 (20%) Query: 584 LLNFSQMGRSALRLADVDLNTLVDTIRQEFE--PDY----QGR--EIIWMVASMPKVIAD 635 L + S++ R +LR ++ +L E Y + + + + I D Sbjct: 197 LTSLSELMRYSLRYSNARQVSL----ADELTVVDSYLQLASIQFEDRLQFENQINPAIMD 252 Query: 636 PAFINMALYNLIANAIKY--SRGRRPARIEIGAVQHELETEVYVRDNGVGFDMAYANKLF 693 M + L+ N IK+ ++ + +I + + + V + G Sbjct: 253 VQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG------------ 300 Query: 694 GVFQRLHRMEEFEGTGIGLASVRR 717 L E TG GL +VR Sbjct: 301 ----SLALKNTKESTGTGLQNVRE 320
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 25.5 bits (55), Expect = 0.047 Identities = 24/73 (32%), Positives = 31/73 (42%), Gaps = 6/73 (8%) Query: 21 APLPGPLLAANDSNNPYNSPIMRANPNSRQGSVPASP--PVRGPST--QPNPRP--PTLD 74 AP PL + + NP N+P NP +R P P P T QP RP P + Sbjct: 322 APNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVP 381 Query: 75 NRGIGNGDNLRRE 87 +R G R+E Sbjct: 382 DRPNGRHRKERKE 394
>SYCECHAPRONE#Gram-negative bacterial type III secretion SycE chaperone signature. Length = 130 Score = 117 bits (295), Expect = 2e-37 Identities = 51/116 (43%), Positives = 70/116 (60%), Gaps = 5/116 (4%) Query: 5 NYDYALTQLYAALKLEPPAAFEPVISLRVGPHVCNVTEHPADQLLMFIELPTLDD----V 60 +++ A+TQL+ L L P EPVI ++VG C++TEHP Q+LMF LP+LD+ Sbjct: 3 SFEQAITQLFQQLSLSIPDTIEPVIGVKVGEFACHITEHPVGQILMFT-LPSLDNNDEKE 61 Query: 61 RWGEQNLFCQDLCKPLLGADPLTGMQVLWNRQSLLQMDRAMVHHQLEQLVQAAHDL 116 N+F QD+ KP+L D + G VLWNRQ L +D ++ QLE LVQ A L Sbjct: 62 TLLSHNIFSQDILKPILSWDEVGGHPVLWNRQPLNSLDNNSLYTQLEMLVQGAERL 117
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 47.9 bits (114), Expect = 7e-10 Identities = 19/119 (15%), Positives = 35/119 (29%), Gaps = 7/119 (5%) Query: 20 LPTQLARRLGMAPWLADEAGVYHLCIDG-HGLRLEPRGTQWRVGSSLSSVVGQGAGLDRQ 78 L +R L M P + D+ G ++ ID L L ++G Sbjct: 9 LLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDY-----ARERLLLIGLLEPHKDI 63 Query: 79 TLRRLLGMVTGWAAHCPQRLAMTAEGELLLEAW-IDAAQGDVGTFEHVLGVQVALLDIL 136 + LL + L + + L I + V T + + + + Sbjct: 64 PQQCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMRGW 122
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.1 bits (70), Expect = 3e-04 Identities = 8/50 (16%), Positives = 20/50 (40%), Gaps = 3/50 (6%) Query: 14 VLPSFMGQGIARRMVEHLEGIARVEGLETVHLDAT-LNAAA--FYRRCGY 60 V + +G+ ++ A+ + L+ +N +A FY + + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 279 bits (714), Expect = 1e-95 Identities = 146/289 (50%), Positives = 183/289 (63%), Gaps = 9/289 (3%) Query: 38 ASNESAQGEALSPAAAPVKSGPYLSDWYNQNFTLIGTKDISFGPRPVDDIYLEYEYFGRK 97 A A + AA YLSDW++Q+ ++G+ FGP+ +D YLEYE F +K Sbjct: 8 AGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEYEAFAKK 67 Query: 98 GPFELYGYIDIPKILDIGNSHDKGAWDHGSPLFMEHEPRISIDYLAGRSLAVGPFKEWYV 157 F+ YGYID P GNS KG W+ GSPLFME EPR SID L L+ GPFKEWY Sbjct: 68 DWFDFYGYIDAPVFFG-GNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYF 126 Query: 158 AFDWIYDHGSNSANRANTLYSGLGTDIDTHSRVNLSANFYGRYQWENYGASNEYSWDGYR 217 A ++IYD G N + +T Y GLGTDIDT ++LS N Y +YQW+NYGASNE WDGYR Sbjct: 127 ANNYIYDMGRNDSQEQSTWYMGLGTDIDTGLPMSLSLNVYAKYQWQNYGASNENEWDGYR 186 Query: 218 AQLKYIVPLGKFDNGASLTYIGFTNFDFGSDLHKDN-------PNRTANATVSTNVLLYA 270 ++KY VPL G SL+YIGFTNFD+GSDL DN RT+N+ S+++L Sbjct: 187 FKVKYFVPLTDL-WGGSLSYIGFTNFDWGSDLGDDNFYDLNGKHARTSNSIASSHILALN 245 Query: 271 FTHLRFTLVGRHFHNGGNWQDGSQLNFGDGDFRGRSDGWGYYAGVGYQF 319 + H +++V R+FHNGG W D ++LNFGDG F RS GWG Y VGY F Sbjct: 246 YAHWHYSIVARYFHNGGQWADDAKLNFGDGPFSVRSTGWGGYFVVGYNF 294
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 4e-28 Identities = 79/257 (30%), Positives = 109/257 (42%), Gaps = 31/257 (12%) Query: 5 KVAIITAGGSGMGAEAARRLAADGFRVA----------ILSSSGKGEALAAELGGIGVTG 54 K+A IT G+G AR LA+ G +A + SS K EA AE V Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 55 SNQSVEDLQRLVDTVMQQWGRVDVLVNSAGHGPRAPILELSDDDWHRGMEVYFLNVVRPT 114 S E R+ ++ G +D+LVN AG I LSD++W V V + Sbjct: 69 SAAIDEITARI----EREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 115 RLVTPIMQRQGGGAIINISTFAAFEPDPAFPTSGVFRAGLAAFTKLFADRYAAENIRMNN 174 R V+ M + G+I+ + + A P + +A FTK A NIR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 175 VLPGFIDSLPEK-----------------EEFRNRIPMERYGKSEEIAATVAFLASEGAG 217 V PG ++ + E F+ IP+++ K +IA V FL S AG Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 218 YITGQNLRVDGGITRSV 234 +IT NL VDGG T V Sbjct: 245 HITMHNLCVDGGATLGV 261
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.8 bits (64), Expect = 0.007 Identities = 10/57 (17%), Positives = 24/57 (42%), Gaps = 3/57 (5%) Query: 89 VIMSVVLDPAYQGLGHASRLMARFVEQMRERGKATIHLMCKDRHVG---LYEKMGYT 142 +I + + Y+ G + L+ + +E +E + L +D ++ Y K + Sbjct: 91 LIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 51.6 bits (123), Expect = 3e-10 Identities = 42/158 (26%), Positives = 57/158 (36%), Gaps = 12/158 (7%) Query: 5 ANNAALLIIDMQNGINHP-RLGRRNNPEAEQRINQLLASWRASMRPVVHVRH-VSRDPD- 61 N A LLI DMQN G E I +L PVV+ S++PD Sbjct: 28 PNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 62 ----SVFW-PGQPGCEFQ----PAFTPQASETVFEKHVPDAFCNSGLERWLHQRGISQLV 112 + FW PG ++ P+ + V K AF + L + + G QL+ Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLI 147 Query: 113 IVGVITNNSVESTARSAGNLGFDTVVVGDACYTFDQHD 150 I G+ + TA A VGDA F Sbjct: 148 ITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEK 185
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.011 Identities = 12/33 (36%), Positives = 18/33 (54%), Gaps = 4/33 (12%) Query: 31 ALAPG---EVVSIL-GPSGVGKSSLLRVLAGLQ 59 + PG + +L G G+GKS+L+ L GL Sbjct: 588 VMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLD 620
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 28.2 bits (62), Expect = 0.026 Identities = 9/16 (56%), Positives = 13/16 (81%) Query: 162 ATRWETLCKVVIPGVI 177 ATRW+ LC++ PGV+ Sbjct: 213 ATRWQELCRLAAPGVV 228
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.003 Identities = 42/272 (15%), Positives = 73/272 (26%), Gaps = 27/272 (9%) Query: 61 NPELSWEVEDTRRDTSTTTVTLSQALELGGKRGARIEVAEAGQAIARLELERQRNSLRAD 120 NPE+ + T T+ TT QA V + IAR+ + Sbjct: 982 NPEVE-KRNQTVDTTNITTPNNIQA--------DVPSVPSNNEEIARV-----DEAPVPP 1027 Query: 121 VIQAFHAALRAQTALELAQQSQALTERGLRVVEGRVRAGQ-----SSPVEATRAQVQLAQ 175 A + A Q+S+ + + E + + S V+A ++AQ Sbjct: 1028 PAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQ 1087 Query: 176 AEAAVRRA-RTERGVANQVLARLTGSAEARFDRLDASNLSPGPAPQAEPLLAKVE-QTAE 233 + + + TE V E + S Q + + + + A Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAR 1147 Query: 234 WRLAAAQIERGDASLGSEKAQRIPNLTVSLGSQYSREDRERVNVVGLSMPLPLFDRNQGN 293 I+ + + P S + V N N Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKET------SSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 294 VLAAARRADQARDLRNAVELRLRSETRSALEQ 325 A + + N + R R RS Sbjct: 1202 TTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 4e-06 Identities = 23/136 (16%), Positives = 47/136 (34%), Gaps = 13/136 (9%) Query: 137 ASQQISELRSEQQAAQRRLELARLTFEREKQLWQERISAEQDYLQARQALQEAEIAAANA 196 A ++ +S+ + + + A+ ++ QL++ I + L E+A Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 197 GQKVAAVAPAGKGNRYELRAPFDAVVVE-KHLTVGEVVDETSNAFTLS-DLSRVWATFAV 254 Q +RAP V + K T G VV + + + T V Sbjct: 324 RQ-----------QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALV 372 Query: 255 APRDLDKVVSGRGVSV 270 +D+ + G+ + Sbjct: 373 QNKDIGFINVGQNAII 388 Score = 34.8 bits (80), Expect = 6e-04 Identities = 18/123 (14%), Positives = 42/123 (34%), Gaps = 7/123 (5%) Query: 80 LAIAGPRTLGTAISFPGEIRFDEDRTAHVVPRVPGVVESVQAELGQAVKRGQVLAVIASQ 139 ++ + + G++ + P +V+ + + G++V++G VL + + Sbjct: 72 FILSVLGQVEIVATANGKLTHSGRSKE-IKPIENSIVKEIIVKEGESVRKGDVLLKLTAL 130 Query: 140 QISELRSEQQAAQRRLELARLTFEREKQLWQERISAEQDYLQARQALQEAEIAAANAGQK 199 ++ Q L ARL R S E + L + E + + Sbjct: 131 G---AEADTLKTQSSLLQARLEQTR---YQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 200 VAA 202 + Sbjct: 185 LRL 187
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 784 bits (2025), Expect = 0.0 Identities = 232/1062 (21%), Positives = 429/1062 (40%), Gaps = 55/1062 (5%) Query: 5 LIQFAIEQRLVVMLAVVLMAAVGIHSYQKLPIDAVPDITNVQVQINTAAPGYSPLETEQR 64 + F I + + + +++ G + +LP+ P I V ++ PG + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 ITFAIETAMAGLPGLKQTRSLSRS-GLSQVTVIFDDGTDIFFARQLVNERLQVAREQLPE 123 +T IE M G+ L S S S G +T+ F GTD A+ V +LQ+A LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 GIEAAMGPISTGLGEIFLWTVEADGGAVKDDGTPYTATDLRVIQDWIIKPQLRNVPGVAE 183 ++ + +L D T D+ +K L + GV + Sbjct: 121 EVQQQGISVEKSSS-SYLMVA-----GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD 174 Query: 184 VNSIGGHAKQYLIAPEPKRLAAYKLTLNDLVAALERNNANVGAGYI------ERNGEQLL 237 V G I + L YKLT D++ L+ N + AG + Sbjct: 175 VQLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 238 IRAPGQVASAEDIANIVI-SSVDGTPIRVSHVAQVGLGQELRSGAATENGREVVLGTVFM 296 I A + + E+ + + + DG+ +R+ VA+V LG E + A NG+ + + Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKL 293 Query: 297 LIGENSRTVSQAVAAKLEEINRSLPKGVVAITVYDRTNLVEKAIATVKKNLIEGAILVIA 356 G N+ ++A+ AKL E+ P+G+ + YD T V+ +I V K L E +LV Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 357 VLFLFLGNIRAALITAMVIPLSMLFTFTGMFSNKVSANLMSLG--ALDFGIIVDGAVVIV 414 V++LFL N+RA LI + +P+ +L TF + + S N +++ L G++VD A+V+V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 415 ENAIRRLAHAQQHHGRMLTRSERFHEVFAAAREARRPLIYGQLIIMVVYLPIFALTGVEG 474 EN R + + + + + L+ +++ V++P+ G G Sbjct: 414 ENVERVMMEDK---------LPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 475 KMFHPMAFTVVMALLGAMILSVTFVPAALALFVTGKVKEEEGA----------VMRTARR 524 ++ + T+V A+ ++++++ PA A + E + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVN 524 Query: 525 RYAPVLDWVLGRRNLAFAGAATVVLLSGVLASRMGSEFIPSLSEGDFALQALRVPGTSLS 584 Y + +LG A +V VL R+ S F+P +G F G + Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584 Query: 585 QSVD-MQQRLEKTIIAQVPEVERVFARTGTAEIASDPMPPNISDAYVMLKPREQWQDPGK 643 ++ + Q + + + VE VF G + N A+V LKP E+ Sbjct: 585 RTQKVLDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDEN 641 Query: 644 PRDELIFEVQRAAASVPGSNYELSQPIQLRFNELISGVRSDVA-VKVFGDDMEVLNRTAA 702 + +I + + EL + D + G + L + Sbjct: 642 SAEAVIHRAKMELGKIRDGFVIPFNM--PAIVELGTATGFDFELIDQAGLGHDALTQARN 699 Query: 703 QIAASLQQVPGA-SEVKVEQTTGLPVLTIDIDRDKAARYGLNVGDVQDAIAIAVGGRTAG 761 Q+ Q P + V+ +++D++KA G+++ D+ I+ A+GG Sbjct: 700 QLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVN 759 Query: 762 TLYEGDRRFDMVVRLSEALRTDVDGLSGLLIPVPASAAAGASQIGFIPLSQVANLNLQLG 821 + R + V+ R + + L + +A G +P S + G Sbjct: 760 DFIDRGRVKKLYVQADAKFRMLPEDVDKLYVR----SANG----EMVPFSAFTTSHWVYG 811 Query: 822 PNQVSREDGKRVVVVSANVRGRDLGSFVEQASQTLIDQVQIPPGYWTRWGGQFEQLQSAA 881 ++ R +G + + + L ++P G W G Q + + Sbjct: 812 SPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENL--ASKLPAGIGYDWTGMSYQERLSG 869 Query: 882 ERLRVVVPISLLLVMALLLMMFNNLKDGLLVFTGIPFALTGGVLALWLRDIPLSISAGVG 941 + +V IS ++V L ++ + + V +P + G +LA L + + VG Sbjct: 870 NQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVG 929 Query: 942 FIALSGVAVLNGLVMIAFIRNLRE-EGRSLRAAVEEGALTRLRPVLMTALVASLGFIPMA 1000 + G++ N ++++ F ++L E EG+ + A RLRP+LMT+L LG +P+A Sbjct: 930 LLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLA 989 Query: 1001 LATGTGAEVQRPLATVVIGGILSSTALTLLVLPALYQWAHRR 1042 ++ G G+ Q + V+GG++S+T L + +P + R Sbjct: 990 ISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 5e-07 Identities = 28/152 (18%), Positives = 56/152 (36%), Gaps = 6/152 (3%) Query: 47 PLALASTLPGRVEPM-RVAEVRARVAGIVLHKRFEEGADVKAGDVLFQIDPAPFKAALAR 105 + + +T G++ R E++ IV +EG V+ GDVL ++ +A + Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 106 AEADLARAQAVQHEAQARVKRYE--PLVKIEAVSQQDFDSATAELRSAQAAVRSAQADV- 162 ++ L +A+ Q Q + E L +++ + F + + E ++ Q Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 163 --QTARLNLGYATVTAPISGRIGRALATEGAL 192 Q + L A + R E Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Score = 42.9 bits (101), Expect = 1e-06 Identities = 18/115 (15%), Positives = 46/115 (40%), Gaps = 4/115 (3%) Query: 100 KAALARAEADLARAQAVQHEAQARVKRYEPLVKIEAVSQQDFDSATAELRSAQAAVRSAQ 159 + A +L ++ + ++ + + + + V+Q + +LR + Sbjct: 258 ENKYVEAVNELRVYKSQLEQIESEILSAK--EEYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 160 ADVQTARLNLGYATVTAPISGRI-GRALATEGALVGQGDATLMARIQQLDPIYVD 213 ++ + + AP+S ++ + TEG +V + TLM + + D + V Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVT 369
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1128 bits (2918), Expect = 0.0 Identities = 511/1034 (49%), Positives = 698/1034 (67%), Gaps = 7/1034 (0%) Query: 1 MSKFFINRPNFAWVVALFISLAGLLVIPALPVAQYPSVAPPQISITASYPGASAKVLVES 60 M+ FFI RP FAWV+A+ + +AG L I LPVAQYP++APP +S++A+YPGA A+ + ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTSIIEESLNGAKGLLYYESTNNSNGVAEVLVTFEPGTKPDMAQVDVQNRLKKAEARMPQ 120 VT +IE+++NG L+Y ST++S G + +TF+ GT PD+AQV VQN+L+ A +PQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVLTQGLKVEQASSGFLLIYALTSKAGDRGDTTALADYAARNINNELLRVPGVGKLQFFA 180 V QG+ VE++SS +L++ S ++DY A N+ + L R+ GVG +Q F Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGT-TQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 181 SEAAMRVWVDPQKLVGYGLSIDDINNAIRGQNVQVPAGSFGSTPGASEQELTATLAVQGT 240 ++ AMR+W+D L Y L+ D+ N ++ QN Q+ AG G TP Q+L A++ Q Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LDTPEAFAGIVLRANPDGSSVRLGDVARLAIGSENYNLSSRLDGHPAVAGAVQLAPGANA 300 PE F + LR N DGS VRL DVAR+ +G ENYN+ +R++G PA ++LA GANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 IQTATLVKERLAELAQFFPEGVEYSVPYDTSRFVDVAIEKVIHTLIEAMVLVFLVMFLFL 360 + TA +K +LAEL FFP+G++ PYDT+ FV ++I +V+ TL EA++LVFLVM+LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QNVRYTLIPSIVVPVCLLGTLMIMKLLGFSVNMMTMFGMVLAIGILVDDAIVVVENVERL 420 QN+R TLIP+I VPV LLGT I+ G+S+N +TMFGMVLAIG+LVDDAIVVVENVER+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 MAEEGLSPVDATIKAMGQVSGAIIGITLVLAAVFLPLAFMSGSVGVIYQQFSVSLAVSIL 480 M E+ L P +AT K+M Q+ GA++GI +VL+AVF+P+AF GS G IY+QFS+++ ++ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 481 FSGFLALTFTPALCATLLKPVPHGHHE-KGGFFGAFNRAFVRVTERYSVMNSALVARAGR 539 S +AL TPALCATLLKPV HHE KGGFFG FN F Y+ ++ GR Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 540 WMLAYVGILVVLGYSYLRLPEAFVPSEDLGYSIVDVQLPPGASRVRTDHTAEALEQFLLS 599 ++L Y I+ + +LRLP +F+P ED G + +QLP GA++ RT + + + L Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 600 REAT--ASSFIVSGFSFSGQGDNAALAFPTFKDWSVR-GPEQSAEAETAAINAQFAANGD 656 E S F V+GFSFSGQ NA +AF + K W R G E SAEA + D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 657 GTITAVMPPPIDGLGNSGGFALRLMDRGGLGREALLAARDQLLARANGNPVILYAMM-EG 715 G + P I LG + GF L+D+ GLG +AL AR+QLL A +P L ++ G Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 716 LAEAPQLRVQIDREKARALGVSFETINSTLATAFGSAVINDFTNAGRQQRVVVQAEQGER 775 L + Q ++++D+EKA+ALGVS IN T++TA G +NDF + GR +++ VQA+ R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 776 MTPESVLRLYAPNTGGEQVPFSAFVTTKWEEGPVQLVRYNGYPSIRIAGDAAPGHSTGQA 835 M PE V +LY + GE VPFSAF T+ W G +L RYNG PS+ I G+AAPG S+G A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 836 MAEMERLVSELPPGIGYAWTGLSYQEKVSSGQATALFALAILVVFLLLVALYESWAIPLT 895 MA ME L S+LP GIGY WTG+SYQE++S QA AL A++ +VVFL L ALYESW+IP++ Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 896 VMLIVPIGALGAVWAVMLTGLPNDVYFKVGLITIIGLAAKNAILIVEFAKELWEK-GYSL 954 VML+VP+G +G + A L NDVYF VGL+T IGL+AKNAILIVEFAK+L EK G + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 955 SDAAIEAARLRFRPIVMTSMAFILGVVPLAIATGAGAASQRAIGTGVIGGMLSATLLGVV 1014 +A + A R+R RPI+MTS+AFILGV+PLAI+ GAG+ +Q A+G GV+GGM+SATLL + Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1015 FVPICFVFVLKLLK 1028 FVP+ FV + + K Sbjct: 1020 FVPVFFVVIRRCFK 1033 Score = 81.4 bits (201), Expect = 1e-17 Identities = 57/323 (17%), Positives = 114/323 (35%), Gaps = 13/323 (4%) Query: 721 QLRVQIDREKARALGVSFETINSTLATA---FGSAVINDFTNAGRQQRVVVQAEQGERMT 777 +R+ +D + ++ + + L + + QQ Q Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 778 PESVLRLY-APNTGGEQVPFSAFVTTKW-EEGPVQLVRYNGYPSIRIAGDAAPGHST--- 832 PE ++ N+ G V + E + R NG P+ + A G + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 833 -GQAMAEMERLVSELPPGIGYAWTGLSYQEKVSSGQATALFAL--AILVVFLLLVALYES 889 A++ L P G+ + V + L AI++VFL++ ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYP-YDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 890 WAIPLTVMLIVPIGALGAVWAVMLTGLPNDVYFKVGLITIIGLAAKNAILIVE-FAKELW 948 L + VP+ LG + G + G++ IGL +AI++VE + + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 949 EKGYSLSDAAIEAARLRFRPIVMTSMAFILGVVPLAIATGAGAASQRAIGTGVIGGMLSA 1008 E +A ++ +V +M +P+A G+ A R ++ M + Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 1009 TLLGVVFVPICFVFVLKLLKRKP 1031 L+ ++ P +LK + + Sbjct: 482 VLVALILTPALCATLLKPVSAEH 504
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1137 bits (2943), Expect = 0.0 Identities = 545/1031 (52%), Positives = 735/1031 (71%), Gaps = 7/1031 (0%) Query: 1 MPQFFIDRPVFAWVVALFILLVGALAIPQLPVAQYPDVAPPQVEIYAVYPGASAATMDES 60 M FFI RP+FAWV+A+ +++ GALAI QLPVAQYP +APP V + A YPGA A T+ ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VVSIIEQELNGADNLLYFESQS-SLGSATITASFQPGTNPDMAQVDVQNRLKVIESRLPR 119 V +IEQ +NG DNL+Y S S S GS TIT +FQ GT+PD+AQV VQN+L++ LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 120 PVTQQGLQVEKVSTGFLLLATLTSEDGNLDEIALSDILARNVMNEIRRIKGVGKAQLYGS 179 V QQG+ VEK S+ +L++A S++ + +SD +A NV + + R+ GVG QL+G+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 ERAMRIWIDPAKLVGFNLTPNDVAEAIAAQNAQVAPGSIGDLPSRPTQEITANVVVKGQL 239 + AMRIW+D L + LTP DV + QN Q+A G +G P+ P Q++ A+++ + + Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 240 STPEEFAAIVLRANTDGSTVTVGDVARVEIGAQEYQYGTRLNGKATSAFSVKLSPGANAM 299 PEEF + LR N+DGS V + DVARVE+G + Y R+NGK + +KL+ GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 300 ETAGLVKQKLDELARYFPAGVKYDIPYDTSPFVKVSIKQVINTLVEAMVLVFAVMFLFLQ 359 +TA +K KL EL +FP G+K PYDT+PFV++SI +V+ TL EA++LVF VM+LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 360 NFRYTLIPTLVVPVALMGTFAVMNALGFSINVLTLFGMVLAIGILVDDAIVVVENVERIM 419 N R TLIPT+ VPV L+GTFA++ A G+SIN LT+FGMVLAIG+LVDDAIVVVENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 420 AEEGLPPKEATRKAMGQISGAIVGITLVLVAVFLPMAFMKGSVGVIYQQFSVSMAVSILF 479 E+ LPPKEAT K+M QI GA+VGI +VL AVF+PMAF GS G IY+QFS+++ ++ Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 480 SAFLALSLTPALCATLLKPLEKGEHHERKGFFGWFNRRFEGMSNGYQRWVTHALARSGRY 539 S +AL LTPALCATLLKP+ H + GFFGWFN F+ N Y V L +GRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 540 LLVYAVLLAVLGYGFSQLPTAFLPTEDQGYTITDIQLPPGASQARTIEVARQIE--AHNA 597 LL+YA+++A + F +LP++FLP EDQG +T IQLP GA+Q RT +V Q+ Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 598 EEPGVANTTLILGFSFSGSGQNAALAFTTLKDWSERGGDD-SAQSIADRATLAFTQLKDA 656 E+ V + + GFSFSG QNA +AF +LK W ER GD+ SA+++ RA + +++D Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 657 IAYAVLPPPVDGLGESTGFEFRLQDRGGMGHTALMQARDQLLEAARKSKV-LVNVREASL 715 P + LG +TGF+F L D+ G+GH AL QAR+QLL A + LV+VR L Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 716 AESPQVELEIDRRQANALGVSFADIGAVLDTAVGSNYVNDFPNQGRMQRVVVQAEGDRRS 775 ++ Q +LE+D+ +A ALGVS +DI + TA+G YVNDF ++GR++++ VQA+ R Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 776 QVEDLLKIHVRNNSGKMVPLGAFVSAHWQSGPVQLTRYNGYPAVSISGEPAAGHSSGEAM 835 ED+ K++VR+ +G+MVP AF ++HW G +L RYNG P++ I GE A G SSG+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 836 AEVEHLVAQLPAGAGLEWTGLSLQERLSGSQAPLLMALSLLVVFLCLAALYESWSIPTAV 895 A +E+L ++LPAG G +WTG+S QERLSG+QAP L+A+S +VVFLCLAALYESWSIP +V Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 896 LLVVPLGVLGAVLAVTLRGMPNDVYFKVGLITLIGLSAKNAILIIEFAKALVD-QGHDAV 954 +LVVPLG++G +LA TL NDVYF VGL+T IGLSAKNAILI+EFAK L++ +G V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 955 DAAIQAARLRLRPIVMTSLAFILGVVPLAIASGASSASQQAIGTGVIGGMLSATF-AVVF 1013 +A + A R+RLRPI+MTSLAFILGV+PLAI++GA S +Q A+G GV+GGM+SAT A+ F Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1014 VPVFFVVVMRL 1024 VPVFFVV+ R Sbjct: 1021 VPVFFVVIRRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.7 bits (98), Expect = 3e-06 Identities = 29/222 (13%), Positives = 79/222 (35%), Gaps = 28/222 (12%) Query: 46 AVQPLAISTELSGRI-LAPRTAEVRARVAGVVLKRVYREGSDVKQGDVLFLIDPAPFKAD 104 + + I +G++ + R+ E++ +V + + +EG V++GDVL + +AD Sbjct: 76 VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEAD 135 Query: 105 FDSARATL--AKAEATLYQARLQEQRYRELVDDKAVSRQEYDNARAAFLQADAAVGEAKA 162 +++L A+ E T YQ + +L + K + N + ++ + + Sbjct: 136 TLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Query: 163 ALERARLNLGYATVTAPISGRIG----------------------RALVTEGALVGQNET 200 + + + + + R+ +L+ + A + ++ Sbjct: 196 STWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA-IAKHAV 254 Query: 201 TPLATIQQLNPIHADVTQSTRELNALRRALRAGELRQVGQDQ 242 L + ++ +L + + + + Q Sbjct: 255 --LEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQ 294 Score = 33.6 bits (77), Expect = 0.001 Identities = 19/99 (19%), Positives = 34/99 (34%), Gaps = 6/99 (6%) Query: 108 ARATLAKAEATLYQARLQ----EQRYRELVDDKAVSRQEYDN-ARAAFLQADAAVGEAKA 162 +A L + Q E ++ + Q + N Q +G Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 163 ALERARLNLGYATVTAPISGRIGRALV-TEGALVGQNET 200 L + + + AP+S ++ + V TEG +V ET Sbjct: 317 ELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 3e-22 Identities = 30/136 (22%), Positives = 62/136 (45%) Query: 2 PNILLVEDDSALSELIASYLQRNDFHVRVIARGDHVLDEFRRQKPDLVILDLMLPGLDGL 61 IL+ +DD+A+ ++ L R + VR+ + + DLV+ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QVCRLLRQESQGLPILMLTARDDSHDQVLGLEMGADDYVTKPCEPRVLLARVRTLLRRSS 121 + +++ LP+L+++A++ + E GA DY+ KP + L+ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 VNEPRLDSDLIQVGGL 137 +L+ D L Sbjct: 124 RRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 34.5 bits (79), Expect = 8e-04 Identities = 31/185 (16%), Positives = 70/185 (37%), Gaps = 39/185 (21%) Query: 259 ELDELVLELLSYSRLDSVDQARERVEVSL---LELVDSVLGSFAEELDNRGIRWEVRCET 315 + E++ L R S+ + R +VSL L +VDS L + + ++R +++E + Sbjct: 192 KAREMLTSLSELMRY-SLRYSNAR-QVSLADELTVVDSYLQLASIQFEDR-LQFENQINP 248 Query: 316 DL-----PRFVLDPRLTARAVQNLVRNAMRYCDESLLLRLR-REEDGACLVTVEDDGIGI 369 + P ++ V+N +++ + + + L+ +++G + VE+ G Sbjct: 249 AIMDVQVPPMLVQT-----LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 370 PTEERERIFQPFYRLDRSRDRNTGGFGLGLAISRRAIE---GQGGTLTVAQSALGGAQFR 426 +E G GL R ++ G + ++ G Sbjct: 304 LKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLS-EKQGKVNAM 344 Query: 427 IRLPA 431 + +P Sbjct: 345 VLIPG 349
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 32.6 bits (74), Expect = 0.002 Identities = 18/80 (22%), Positives = 32/80 (40%), Gaps = 4/80 (5%) Query: 132 LPVSGWYLPLELDDLHFRDAARRGALYTQLQAFNRQLDKPLHISAFSAGQLSPRVNG--- 188 L W L+ + + A+ +L L F D + +S ++S + Sbjct: 20 LSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKVSGQFEHDNP 79 Query: 189 -AWLEQLASLGLNVWWQDGA 207 +L+ +ASL VW+ DG Sbjct: 80 QDFLQHIASLYNLVWYYDGN 99
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1101 bits (2848), Expect = 0.0 Identities = 433/1048 (41%), Positives = 647/1048 (61%), Gaps = 25/1048 (2%) Query: 4 SKFFITRPIFAAVLSLVLLIAGSISLFQLPISEYPEVVPPTVVVRANFPGANPKVIGETV 63 + FFI RPIFA VL+++L++AG++++ QLP+++YP + PP V V AN+PGA+ + + +TV Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 AAPLEQAITGVENMLYMSSQSTADGKLTLTITFALGTDLDNAQVQVQNRVTRTQPKLPEE 123 +EQ + G++N++YMSS S + G +T+T+TF GTD D AQVQVQN++ P LP+E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 124 VTRIGITVDKASPDLTMVVHLTSPDNRYDMLYLSNYAILNIKDELARLGGVGDVQLFGMG 183 V + GI+V+K+S MV S + +S+Y N+KD L+RL GVGDVQLFG Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-A 180 Query: 184 DYSLRVWLDPNKTASRNLTASDVVAAIREQNRQVAAGQLGAPPAPGSTSFQLSINTQGRL 243 Y++R+WLD + LT DV+ ++ QN Q+AAGQLG PA SI Q R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 244 VNEEEFENIIIRAGANGEITRLKDIARVELGSSQYALRSLLNNQPAVAIPIFQRPGSNAI 303 N EEF + +R ++G + RLKD+ARVELG Y + + +N +PA + I G+NA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 304 EISDEVRAKMAELKKDFPEGMDYSIVYDPTVFVRGSIEAVVHTLFEALILVVLVVILFLQ 363 + + ++AK+AEL+ FP+GM YD T FV+ SI VV TLFEA++LV LV+ LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 364 TWRASIIPLMAVPVSLIGTFAVMHLFGFSLNALSLFGLVLAIGIVVDDAIVVVENVER-N 422 RA++IP +AVPV L+GTFA++ FG+S+N L++FG+VLAIG++VDDAIVVVENVER Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 423 IGLGLKPLEATQKAMSEVTGPIIATALVLCAVFVPAAFISGLTGQFYKQFALTIAISTVI 482 + L P EAT+K+MS++ G ++ A+VL AVF+P AF G TG Y+QF++TI + + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 483 SAFNSLTLSPALAAVLLK----DHHAPKDRFSRFLEKLLGSWLFAPFNRFFDRASHGYVG 538 S +L L+PAL A LLK +HH K F F FN FD + + Y Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGF------------FGWFNTTFDHSVNHYTN 528 Query: 539 GVRRVIRSSGIALFVYAGLMGLTYLGFSSTPTGFVPAQDKQYLVAFAQLPDAASLDRTEA 598 V +++ S+G L +YA ++ + F P+ F+P +D+ + QLP A+ +RT+ Sbjct: 529 SVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQK 588 Query: 599 VIKKMSEIALKQPGVADSVAF--PGLSINGFTNSPNSGIVFTPLKPFDERKDPSQSAAAI 656 V+ ++++ LK F G S +G + N+G+ F LKP++ER SA A+ Sbjct: 589 VLDQVTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 657 AAALNAQFADIQDAYIAIFPPPPVQGLGTIGGFRLQIEDRGNLGYEALYKETQNIIAK-S 715 + I+D ++ F P + LGT GF ++ D+ LG++AL + ++ + Sbjct: 647 IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAA 706 Query: 716 HNVPELAGLFTSYQVNVPQVDAAIDREKAKTHGVAINDIFDTLQVYLGSLYTNDFNRFGR 775 + L + + + Q +D+EKA+ GV+++DI T+ LG Y NDF GR Sbjct: 707 QHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGR 766 Query: 776 TYQVNVQAEQQFRLDAEQIGQLKVRNNLGEMIPLATFLKVSDTSGPDRVMHYNGFITAEI 835 ++ VQA+ +FR+ E + +L VR+ GEM+P + F G R+ YNG + EI Sbjct: 767 VKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEI 826 Query: 836 NGAAAPGYSSGQAEAAIEKLLKEELPNGMTFEWTDLTYQQILSGNTALFVFPLCVLLAFL 895 G AAPG SSG A A +E L +LP G+ ++WT ++YQ+ LSGN A + + ++ FL Sbjct: 827 QGEAAPGTSSGDAMALMEN-LASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFL 885 Query: 896 VLAAQYESWSLPLAVILIVPMTLLSAITGVIISGGDNNIFTQIGLIVLVGLACKNAILIV 955 LAA YESWS+P++V+L+VP+ ++ + + N+++ +GL+ +GL+ KNAILIV Sbjct: 886 CLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIV 945 Query: 956 EFAKDEQAK-GLDPLAAVLEACRLRLRPILMTSIAFIMGVVPLVFSSGAGSEMRHAMGVA 1014 EFAKD K G + A L A R+RLRPILMTS+AFI+GV+PL S+GAGS ++A+G+ Sbjct: 946 EFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIG 1005 Query: 1015 VFSGMIGVTVFGLFLTPVFFFLIRRFVE 1042 V GM+ T+ +F PVFF +IRR + Sbjct: 1006 VMGGMVSATLLAIFFVPVFFVVIRRCFK 1033 Score = 84.1 bits (208), Expect = 2e-18 Identities = 66/319 (20%), Positives = 128/319 (40%), Gaps = 14/319 (4%) Query: 739 IDREKAKTHGVAINDIFDTL-----QVYLGSLYTNDFNRFGRTYQVNVQAEQQFRLDAEQ 793 +D + + + D+ + L Q+ G L G+ ++ A+ +F+ + E+ Sbjct: 188 LDADLLNKYKLTPVDVINQLKVQNDQIAAGQL-GGTPALPGQQLNASIIAQTRFK-NPEE 245 Query: 794 IGQLKVRNNL-GEMIPLATFLKVSDTSGPDRVM-HYNGFITAEINGAAAPGYSSGQ-AEA 850 G++ +R N G ++ L +V V+ NG A + A G ++ A+A Sbjct: 246 FGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKA 305 Query: 851 AIEKL--LKEELPNGMTFEWT-DLTYQQILSGNTALFVFPLCVLLAFLVLAAQYESWSLP 907 KL L+ P GM + D T LS + + ++L FLV+ ++ Sbjct: 306 IKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRAT 365 Query: 908 LAVILIVPMTLLSAITGVIISGGDNNIFTQIGLIVLVGLACKNAILIVEFAKDEQAK-GL 966 L + VP+ LL + G N T G+++ +GL +AI++VE + + L Sbjct: 366 LIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKL 425 Query: 967 DPLAAVLEACRLRLRPILMTSIAFIMGVVPLVFSSGAGSEMRHAMGVAVFSGMIGVTVFG 1026 P A ++ ++ ++ +P+ F G+ + + + S M + Sbjct: 426 PPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA 485 Query: 1027 LFLTPVFFFLIRRFVERRQ 1045 L LTP + + V Sbjct: 486 LILTPALCATLLKPVSAEH 504
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 55.2 bits (133), Expect = 2e-10 Identities = 19/102 (18%), Positives = 43/102 (42%) Query: 65 EVRPRVSGQIDQVAFTEGAQVKKGDLLFQIDPRPFQAEVRRLEAQLQQAKATAIRSANEA 124 E++P + + ++ EG V+KGD+L ++ +A+ + ++ L QA+ R + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 125 RRGERLRDSNAISAELAESRSSAAAEARAGVDAIQAQLDLAR 166 R E + + ++ + E I+ Q + Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Score = 40.2 bits (94), Expect = 1e-05 Identities = 16/115 (13%), Positives = 37/115 (32%), Gaps = 9/115 (7%) Query: 104 RRLEAQLQQAKATAIRSANEARRGERLRDSNAISAELAESR-------SSAAAEARAGVD 156 LE + + +A +++ + + + E + + Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 157 AIQAQLDLARLNLSFTRVTAPISGRVSRAQ-FTAGNIVTADVTPLTSVVSTDKVY 210 + +L + + AP+S +V + + T G +VT L +V D Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA-ETLMVIVPEDDTL 366
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.6 bits (131), Expect = 1e-11 Identities = 34/129 (26%), Positives = 50/129 (38%), Gaps = 4/129 (3%) Query: 1 MRYSTDHKQQTREKLLASSGVLAKRGGFAATGVAGLMKAIGLTGGAFYNHFPSKDDLFSE 60 R + Q+TR+ +L + L + G ++T + + KA G+T GA Y HF K DLFSE Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 IVRRE---LANSPLARLVERGAD-RPRLRRLLEQYLSLAHLHNAEGGCPLPPLGVEIARA 116 I + L + D LR +L L Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 117 ERPVREQAE 125 E V +QA+ Sbjct: 122 EMAVVQQAQ 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.8 bits (176), Expect = 4e-18 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 7/120 (5%) Query: 2 HLLVVEDDDIVRMLIVEVLDELGYTTIEADSAGAALKIIEDPDQALDLLMTDVGLPDLRG 61 +LV +DD +R ++ + L GY +A + I DL++TDV +PD Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA--GDGDLVVTDVVMPDENA 62 Query: 62 EELAAEARKARPGLPVLFASGYAESVTVPEDMHL-----ISKPFSIDQLRDKVQEILGPP 116 +L +KARP LPVL S +T + + KPF + +L + L P Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 2e-17 Identities = 38/123 (30%), Positives = 58/123 (47%), Gaps = 3/123 (2%) Query: 1032 KILLVDDDVRNIFALTSALEHKGAIVEIGRNGREAIECLEANDDIDLVLMDVMMPEMDGY 1091 IL+ DDD L AL G V I N + A D DLV+ DV+MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA-GDGDLVVTDVVMPDENAF 63 Query: 1092 EATRLIRQQPRWRKLPIIAVTAKAMKDDQQRCLQAGANDYLAKPIDLDRLFSLIRVWLPQ 1151 + I++ LP++ ++A+ + + GA DYL KP DL L +I L + Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 1152 LER 1154 +R Sbjct: 122 PKR 124 Score = 71.0 bits (174), Expect = 1e-14 Identities = 35/169 (20%), Positives = 65/169 (38%), Gaps = 16/169 (9%) Query: 765 ILVIEDEPNFARILFDLAHELGYSCLVAHAADEGFELAAQYLPDAILLDMRLPDHSGLTV 824 ILV +D+ +L GY + A + A D ++ D+ +PD + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 825 LQRLKEQAGTRHIPVHIISVEDRVE---AAMHMGAVGYAVKPTSREELKAVFGRLEAKLT 881 L R+K+ +PV ++S ++ A GA Y KP EL + GR A+ Sbjct: 66 LPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 882 QKLKHILLVEDDDLQRESIARLIGD-----DDIQITAVAMAQDALALLR 925 ++ + + L+G + ++ A M D ++ Sbjct: 124 RRPSKLE------DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166 Score = 63.7 bits (155), Expect = 2e-12 Identities = 16/81 (19%), Positives = 32/81 (39%), Gaps = 2/81 (2%) Query: 886 HILLVEDDDLQRESIARLIGDDDIQITAVAMAQDALALLRENIYDCMIIDLKLPDMLGNE 945 IL+ +DD R + + + + + A + D ++ D+ +PD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 946 LLKRMTAEDIRSFPPVIVYTG 966 LL R+ PV+V + Sbjct: 65 LLPRIKKARPD--LPVLVMSA 83
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.0 bits (174), Expect = 2e-15 Identities = 35/169 (20%), Positives = 66/169 (39%), Gaps = 19/169 (11%) Query: 7 AKLLIVDDLPENLLALDALIQGEDREVHQAQSAEQALSLLLEHEFALAILDVQMPGMNGF 66 A +L+ DD L+ + +V +A + + L + DV MP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELAELMRGTEKTRNIPIVFVSAAGREMNYAFKGYESGAVDFLHKPLEPLAVKSKVSVFVD 126 +L ++ + ++P++ +SA M A K E GA D+L KP Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMT-AIKASEKGAYDYLPKP--------------- 105 Query: 127 LFRQRKALDRQLQALEQSRQEQELLLAQLQLARGELERAVRMRDDFMSI 175 F + + +AL + ++ L Q + R+ M++ + + Sbjct: 106 -FDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.0 bits (174), Expect = 1e-17 Identities = 35/117 (29%), Positives = 54/117 (46%), Gaps = 4/117 (3%) Query: 9 VLVVEDEPAIRMILRDYLAGEGYHVLVAEDGEEAFAILASKPHLDLMVTDFRLPGGISGV 68 +LV +D+ AIR +L L+ GY V + + + +A+ DL+VTD +P + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPDE-NAF 63 Query: 69 EIAEPAVKLRPDLKVIFISGYPAEIAESGSPIARQA-PILAKPFDLDTLHEQIQALL 124 ++ K RPDL V+ +S + + A L KPFDL L I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQ-NTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 51.7 bits (124), Expect = 9e-10 Identities = 40/157 (25%), Positives = 59/157 (37%), Gaps = 9/157 (5%) Query: 11 LLLLTGTATLPSTAAAQP-PAQVQRDPSKLHLASGSALLIDLNTNKELYASHADRVRPIA 69 L +++ ATLP A P P + + + +DL + + L A AD P+ Sbjct: 6 LCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 70 SVTKLMTAMVVLDAKLPMDEMLSMTIANNPEMKGVYSRV---RLGSELNRRETLLITLMS 126 S K++ VL DE L I + YS V L + E + Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITM 125 Query: 127 SENRAANTLANHYPGGYGAFIKAMNAKARSLGMSHTR 163 S+N AAN L G + A R +G + TR Sbjct: 126 SDNSAANLLLATVGG-----PAGLTAFLRQIGDNVTR 157
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 53.8 bits (129), Expect = 5e-12 Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 3/79 (3%) Query: 47 ASDEIVGGLYARLG-GRWLFVELLVVPERMRGQGTGRELMAQAEALAREKGCCGIWLDTF 105 + +G + R + +E + V + R +G G L+ +A A+E CG+ L+T Sbjct: 72 LENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQ 131 Query: 106 SFQAP--DFYRKLGFEVFG 122 FY K F + Sbjct: 132 DINISACHFYAKHHFIIGA 150
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 25/158 (15%), Positives = 53/158 (33%), Gaps = 10/158 (6%) Query: 81 ALGTVT-ATNTVNVRSRVAGELVKVHFKEGQQVKAGDLLAEIDPRSYRIALQQAEGTLAQ 139 A G +T + + ++ + ++ KEG+ V+ GD+L ++ AE + Sbjct: 86 ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL-------GAEADTLK 138 Query: 140 NQAQLKNAQVDLARYKGLYAEDSIAKQTLDTAEAQVG--QFQGLVKTNQAQVNDARLNLE 197 Q+ L A+++ RY+ L + K + + + + Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 198 FTQIRAPISGRVGLRQLDLGNLVAANDTTALVVITQTQ 235 Q R L L N L + +++ Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236 Score = 41.0 bits (96), Expect = 6e-06 Identities = 20/123 (16%), Positives = 50/123 (40%), Gaps = 11/123 (8%) Query: 130 LQQAEGTLAQNQAQLKNAQVDLARYKGLYAEDSIAKQTLDTAEAQVGQFQGLVKTNQAQV 189 L+ + L Q ++++ +A+ + L+ + + K L +G ++ Sbjct: 268 LRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK--LRQTTDNIGLLT-------LEL 318 Query: 190 NDARLNLEFTQIRAPISGRV-GLRQLDLGNLVAANDTTALVVITQTQPISVAFTLPETQL 248 + + IRAP+S +V L+ G +V +T +V++ + + V + + Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQNKDI 377 Query: 249 DTV 251 + Sbjct: 378 GFI 380
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 831 bits (2147), Expect = 0.0 Identities = 287/1037 (27%), Positives = 512/1037 (49%), Gaps = 28/1037 (2%) Query: 3 LSRLFILRPVATTLSMLAIVLAGLIAYKLLPVAALPQVDYPTIRVMTLYPGASPQVMTSA 62 ++ FI RP+ + + +++AG +A LPVA P + P + V YPGA Q + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTAPLERQFGQMPGLEQMASTS-SGGASVLTLRFNLDMNMDVAEQQVQAAINAASNLLPN 121 VT +E+ + L M+STS S G+ +TL F + D+A+ QVQ + A+ LLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 DLPAPPVYNKVNPADTPVLTLAISS--KTMPLPKLNDLVDTRVAQKIAQISGVGMVSIAG 179 ++ + + + ++ S ++D V + V +++++GVG V + G Sbjct: 121 EVQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 180 GQRQAVRIKVNVDALAANGLNLDDVRTLIGASNVNQPKGNFDGPTRVS------MLDAND 233 Q +RI ++ D L L DV + N G G + + A Sbjct: 180 AQYA-MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 234 QLRSPEEYANLILKYS-NGAPLRLKDVAEIVDGAENERLAAWANQNEAVLLNIQRQPGAN 292 + ++PEE+ + L+ + +G+ +RLKDVA + G EN + A N A L I+ GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 293 VIEVVDRIKELLPSITDNLPAGLDVSVLTDRTQTIRAAVRDVQHELLFAIALVVMVTFVF 352 ++ IK L + P G+ V D T ++ ++ +V L AI LV +V ++F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 353 LRRFSATIIPSIAVPLSLIGTFGVMYLAGFSVNNLTLMALTIATGFVVDDAIVMLENISR 412 L+ AT+IP+IAVP+ L+GTF ++ G+S+N LT+ + +A G +VDDAIV++EN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 413 HI-EEGETPLQAALKGAKQIGFTLISLTFSLIAVLIPLLFMADVVGRLFREFAITLAVAI 471 + E+ P +A K QI L+ + L AV IP+ F G ++R+F+IT+ A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 472 LISLVVSLTLTPMMCARLLKREPKE--EEQGRFYRASGAWIDWLIKHYGTTLTWVLERQP 529 +S++V+L LTP +CA LLK E E +G F+ D + HY ++ +L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 530 LTLLVAVATLALTVVLYLMVPKGFFPAQDTGVIQGISEAPQSTSFAAMSERQQSLAKVIL 589 LL+ +A VVL+L +P F P +D GV + + P + + + L Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 590 QDPA--VQSLSSYIGVDGDNATLNSGRLLINLKPHGERDV---TASEVINRLQPQLDKLV 644 ++ V+S+ + G N+G ++LKP ER+ +A VI+R + +L K+ Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 645 GIRLFMQPVQDLSIEDRVSRTQYQFSL---SSPDADMLAEWSGKLAQALKDRP-ELQDVA 700 F+ P +I + + T + F L + D L + +L P L V Sbjct: 659 D--GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 701 SDLQDQGLQVFLVIDRDMASRLGITVAQITNALYDAFGQRQISTIYTQASQYRVVLQSQT 760 + + Q L +D++ A LG++++ I + A G ++ + ++ +Q+ Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 761 AASLGPQALESIHVKATDGGQVRLSALARIEQRQAQLAISHIGQFPAVMMSFNLAHGASL 820 + P+ ++ ++V++ +G V SA + P++ + A G S Sbjct: 777 KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSS 836 Query: 821 GEAVKVIEQVQQDIGMPIGVQTRFQGAAEAFQASLSSTLLLILAAVVTMYIVLGVLYESY 880 G+A+ ++E + +P G+ + G + + S + L+ + V +++ L LYES+ Sbjct: 837 GDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESW 894 Query: 881 IHPVTILSTLPSAAVGALLALLLSGNDLGMIAIIGIILLIGIVKKNAIMMIDFALEAERH 940 PV+++ +P VG LLA L + ++G++ IG+ KNAI++++FA + Sbjct: 895 SIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEK 954 Query: 941 QGMSPRDAIYQAALLRFRPILMTTLAALFGAVPLMLATGSGAELRQPLGLVMVGGLLVSQ 1000 +G +A A +R RPILMT+LA + G +PL ++ G+G+ + +G+ ++GG++ + Sbjct: 955 EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSAT 1014 Query: 1001 VLTLFTTPVIYLYFDRL 1017 +L +F PV ++ R Sbjct: 1015 LLAIFFVPVFFVVIRRC 1031 Score = 91.8 bits (228), Expect = 7e-21 Identities = 82/513 (15%), Positives = 172/513 (33%), Gaps = 45/513 (8%) Query: 2 NLSRLFILRPVATTLSMLAIVLAGLIAYKLLPVAALPQVDYPTIRVMTLYPGASPQVMTS 61 N + L IV ++ + LP + LP+ D M P + Q T Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 62 AVTAPLERQFGQMPGLEQMASTSSGGASVLTLRFNLDMNM---------DVAEQQVQAAI 112 V + + + + + G S N M + E +A I Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 113 NAASNLLPNDLPAPPVYNKVNPADTPVLTLAISSKTMP------------LPKLNDLVDT 160 + A +L + ++ L ++ L + + + Sbjct: 648 HRAK----MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLG 703 Query: 161 RVAQKIAQISGVGMVSIAGGQRQAVRIKVNVD--ALAANGLNLDDV----RTLIGASNVN 214 AQ A + V G + K+ VD A G++L D+ T +G + VN Sbjct: 704 MAAQHPASLVSV----RPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVN 759 Query: 215 QPKGNFDGPTRVSMLDANDQLR-SPEEYANLILKYSNGAPLRLKDVAEIVDGAENERLAA 273 G + + A+ + R PE+ L ++ +NG + + RL Sbjct: 760 DF--IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLER 817 Query: 274 WANQNEAVLLNIQRQPGANVIEVVDRIKELLPSITDNLPAGLDVSVLTDRTQTIRAAVRD 333 N ++ + + PG + + + ++ L LPAG+ T + R + Sbjct: 818 -YNGLPSMEIQGEAAPGTSSGDAMALMENLA----SKLPAGIGYDW-TGMSYQERLSGNQ 871 Query: 334 VQHELLFAIALVVMVTFVFLRRFSATIIPSIAVPLSLIGTFGVMYLAGFSVNNLTLMALT 393 + + +V + +S + + VPL ++G L + ++ L Sbjct: 872 APALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLL 931 Query: 394 IATGFVVDDAIVMLENI-SRHIEEGETPLQAALKGAKQIGFTLISLTFSLIAVLIPLLFM 452 G +AI+++E +EG+ ++A L + ++ + + I ++PL Sbjct: 932 TTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS 991 Query: 453 ADVVGRLFREFAITLAVAILISLVVSLTLTPMM 485 I + ++ + ++++ P+ Sbjct: 992 NGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 825 bits (2133), Expect = 0.0 Identities = 300/1038 (28%), Positives = 521/1038 (50%), Gaps = 31/1038 (2%) Query: 3 LSGPFIRRPVATMLLSLAIMLLGGVSFGLLPVSPLPQMDFPVIVVQASLPGASPEVMAST 62 ++ FIRRP+ +L++ +M+ G ++ LPV+ P + P + V A+ PGA + + T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VATPLERKLGAIAGVTTLTSSS-NQGSTRVIIGFELGRDIDGAAREVQAAINATRNLLPS 121 V +E+ + I + ++S+S + GS + + F+ G D D A +VQ + LLP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 GMRSMPTYKKINPSQAPIMVLSLTSD--VLSKGKLYDLADTILSQSLAQVSGVGEVQIGG 179 ++ + S + +MV SD ++ + D + + +L++++GVG+VQ+ G Sbjct: 121 EVQQQGISVE-KSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 180 SSLPAVRIELEPQLLNQYGLSLDDVRNAVANANQRRPMGFV------EDRERNWQVRAND 233 + A+RI L+ LLN+Y L+ DV N + N + G + ++ N + A Sbjct: 180 AQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 234 QLETAEDYKPLVIR-QQNGAILRLSDVAKVSDGVENRYNSGFFNDESAVLLVVNRQTNAN 292 + + E++ + +R +G+++RL DVA+V G EN N + A L + T AN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 293 IIQTVEQIKAELPALQSLLPASVKLNVAMDRSPVIKATLKEAEHTLLIAVVLVILVVYLF 352 + T + IKA+L LQ P +K+ D +P ++ ++ E TL A++LV LV+YLF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 353 LGNLRASLIPSLAVPVSLVGTFAVMYLCGFSLNNLSLMALILATGLVVDDAIVVLENISR 412 L N+RA+LIP++AVPV L+GTFA++ G+S+N L++ ++LA GL+VDDAIVV+EN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 413 HI-ENGENPMRAAYKGAQEVGFTLLSMNVSLVAVFVSILFMGGIVRGLFKEFSITLAAAI 471 + E+ P A K ++ L+ + + L AVF+ + F GG ++++FSIT+ +A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 472 VVSLVVSLTLTPMLCSRWLKIHGPQQQTRLQR---WSDHIHQRMVAGYDKSLGWALRHKR 528 +S++V+L LTP LC+ LK + W + V Y S+G L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 529 LTLLSLLATIGLNIALYVVVPKTLMPQQDTGQLQGFIRGDDGLSFTVMQPKMEIYRRALL 588 LL + + L++ +P + +P++D G I+ G + Q ++ L Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 589 KDPAVE-----SVAGFIGGNSGTNNAFVLVRLKPIAER---KENAQKVIDRLRKDLPKIP 640 K+ +V GF N V LKP ER + +A+ VI R + +L KI Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 641 GGRLYLMADQD-LQLGGGGRDQSTSQYLYTLQSGDLAALREWFPKVAAELRKLP-ELTAI 698 G + ++LG L AL + ++ + P L ++ Sbjct: 659 DGFVIPFNMPAIVELGTATGFDF---ELIDQAGLGHDALTQARNQLLGMAAQHPASLVSV 715 Query: 699 DARDGAGTQQVTLVVDRDQAKRLGIDMDMVTAVLNNAYSQRQISTIYDSLNQYQVVLEIN 758 T Q L VD+++A+ LG+ + + ++ A ++ D ++ ++ + Sbjct: 716 RPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQAD 775 Query: 759 PKYAWDPSTLEQVQVITADGARVPLSTFARYENSLANDRVSHEGQFASEDISFDVAEGYS 818 K+ P ++++ V +A+G VP S F + R+ S +I + A G S Sbjct: 776 AKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTS 835 Query: 819 PDQAMAALERAVAKLGLPESVIAKLGGDADAFTKTTEGQPLMILGALVLVYLVLGILYES 878 AMA +E +K LP + G + + P ++ + V+V+L L LYES Sbjct: 836 SGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYES 893 Query: 879 YIHPLTILSTLPSAGVGALLALYLTGGEFSLISLLGLFLLIGVVKKNAILMIDLALQLER 938 + P++++ +P VG LLA L + + ++GL IG+ KNAIL+++ A L Sbjct: 894 WSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLME 953 Query: 939 HEGLSPEESIRRACLLRLRPILMTTLAAILGALPLLLSRAEGAEMRQPLGLTIIGGLVFS 998 EG E+ A +RLRPILMT+LA ILG LPL +S G+ + +G+ ++GG+V + Sbjct: 954 KEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSA 1013 Query: 999 QILTLYTTPVVYLYLDRL 1016 +L ++ PV ++ + R Sbjct: 1014 TLLAIFFVPVFFVVIRRC 1031 Score = 106 bits (267), Expect = 2e-25 Identities = 84/513 (16%), Positives = 174/513 (33%), Gaps = 45/513 (8%) Query: 2 NLSGPFIRRPVATMLLSLAIMLLGGVSFGLLPVSPLPQMDFPVIVVQASLPGASPEVMAS 61 N G + +L+ I+ V F LP S LP+ D V + LP + + Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 62 TVATPLERKLG-----------AIAGVTTLTSSSNQGSTRVIIGFELGRDIDGAAREVQA 110 V + + G + + N G + + + +G +A Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG--MAFVSLKPWEERNGDENSAEA 645 Query: 111 AINATRNLLPSGMRSMPTYKKINPSQAPIMVLS----LTSDVLSKG-----KLYDLADTI 161 I+ + L + I + I+ L +++ + L + + Sbjct: 646 VIHRAKMELG----KIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 162 LSQSLAQVSGVGEVQIGGSS-LPAVRIELEPQLLNQYGLSLDDVRNAVANANQRRPMGFV 220 L + + + V+ G ++E++ + G+SL D+ ++ A + Sbjct: 702 LGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF 761 Query: 221 EDRERNWQVRA---NDQLETAEDYKPLVIRQQNGAILRLSDVAKVSDG----VENRYNSG 273 DR R ++ ED L +R NG ++ S RYN Sbjct: 762 IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYN-- 819 Query: 274 FFNDESAVLLVVNRQTNANIIQTVEQIKAELPALQSLLPASVKLNVAMDRSPVIKATLKE 333 L + Q A + A + L S LPA + + S + + + Sbjct: 820 -------GLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDW-TGMSYQERLSGNQ 871 Query: 334 AEHTLLIAVVLVILVVYLFLGNLRASLIPSLAVPVSLVGTFAVMYLCGFSLNNLSLMALI 393 A + I+ V+V L + + + L VP+ +VG L + ++ L+ Sbjct: 872 APALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLL 931 Query: 394 LATGLVVDDAIVVLENI-SRHIENGENPMRAAYKGAQEVGFTLLSMNVSLVAVFVSILFM 452 GL +AI+++E + G+ + A + +L +++ + + + Sbjct: 932 TTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS 991 Query: 453 GGIVRGLFKEFSITLAAAIVVSLVVSLTLTPML 485 G G I + +V + ++++ P+ Sbjct: 992 NGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024 Score = 83.3 bits (206), Expect = 3e-18 Identities = 69/415 (16%), Positives = 151/415 (36%), Gaps = 32/415 (7%) Query: 625 AQKVIDRLRKDLPKIPGGRLYLMADQDLQLGGGGRDQSTSQYLYT---------LQSGDL 675 +V ++L+ P +P Q++Q G ++S+S YL D+ Sbjct: 104 QVQVQNKLQLATPLLP---------QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDI 154 Query: 676 AALREWFPKVAAELRKLPELTAIDARDGAGTQQVTLVVDRDQAKRLGIDMDMVTAVLNNA 735 + V L +L + D + + + +D D + + V L Sbjct: 155 SDYVAS--NVKDTLSRLNGVG--DVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQ 210 Query: 736 YSQ----RQISTIYDSLNQYQVVLEINPKYAWDPSTLEQVQV-ITADGARVPLSTFARYE 790 Q + T Q + ++ +P +V + + +DG+ V L AR E Sbjct: 211 NDQIAAGQLGGTPALPGQQLNASIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVE 269 Query: 791 NSLANDR--VSHEGQFASEDISFDVAEGYSPDQAMAALER-AVAKLGLPESVIAKLGGDA 847 N G+ A+ + D A A + A + P+ + D Sbjct: 270 LGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDT 329 Query: 848 DAF-TKTTEGQPLMILGALVLVYLVLGILYESYIHPLTILSTLPSAGVGALLALYLTGGE 906 F + + A++LV+LV+ + ++ L +P +G L G Sbjct: 330 TPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYS 389 Query: 907 FSLISLLGLFLLIGVVKKNAILMIDLALQLERHEGLSPEESIRRACLLRLRPILMTTLAA 966 + +++ G+ L IG++ +AI++++ ++ + L P+E+ ++ ++ + Sbjct: 390 INTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVL 449 Query: 967 ILGALPLLLSRAEGAEMRQPLGLTIIGGLVFSQILTLYTTPVVYLYLDRLRHRFN 1021 +P+ + + +TI+ + S ++ L TP + L + + Sbjct: 450 SAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEH 504
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.003 Identities = 37/219 (16%), Positives = 74/219 (33%), Gaps = 28/219 (12%) Query: 81 QLDALVEELNRSNQTVAQYEAQYRQA--QALVRSSRASLFPSLNLTTSKNRSAQGTGSSS 138 +L AL E + + +A+ Q Q L RS + P L L Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 139 SSLSNNSSGIRDTYNAQLGVSWEIDLWGKLRETMNANESSAEAS-------LADMAAIR- 190 S N + +D R T+ A + E L D +++ Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 191 ---------LSQQSELVQNYLQLRVIDAQKRLLEATVAAYERSLKMNENQYRAGVAGPDA 241 L Q+++ V+ +LRV +Q +E+ + + + ++ ++ Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN------- 298 Query: 242 VAQARTQLKSTQADLIDLAWQRAQYENAIAVLMGKAPAD 280 + +L+ T ++ L + A+ E + +AP Sbjct: 299 --EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVS 335
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 84.5 bits (209), Expect = 6e-20 Identities = 58/408 (14%), Positives = 120/408 (29%), Gaps = 90/408 (22%) Query: 19 KRKIWLLALLLILVLAGAGTWAWYSLVGRWHESTDDAYVNGNVVEITPLVSGTVTSIGAD 78 R+ L+A ++ L A + V + +G EI P+ + V I Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 79 DGDLVHAGQVLLRFDPADSEVALQSAEAKLARTVRQVRGLYSNVDSL------------- 125 +G+ V G VLL+ +E ++ L + + S+ Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 126 ------------------KAQLQTRQAELQKAQQDYHRR--------------------- 146 K Q T Q + + + + ++ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 147 -------KVLADSGAIAA-------EEVAHSRDDLTVAQAAVNSARQQLNTS-------T 185 L AIA + + ++L V ++ + ++ ++ T Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 186 ALVDDTVVSSHPEVMAAAADLRQ----AYLDHARTTLVAPVTGYVAKRTVQ-LGQRLQPG 240 L + ++ + L + + APV+ V + V G + Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 241 TATMAVIPLDEV-WIDANFKETQLRDMRIGQSVEI--TADLYGSEVRYTGTVDSLGAGTG 297 M ++P D+ + A + + + +GQ+ I A Y G V ++ Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA- 412 Query: 298 SAFALLPAQNATGNWIKIVQRVPVRIHLDPEQLKKHPLRIGLSTVAEV 345 G ++ + + K PL G++ AE+ Sbjct: 413 ------IEDQRLGLVFNVIISIEE--NCLSTGNKNIPLSSGMAVTAEI 452
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (305), Expect = 6e-32 Identities = 83/403 (20%), Positives = 163/403 (40%), Gaps = 28/403 (6%) Query: 19 IGLSLATFMQVLDTTIANVALPTISGNLGVSSEQGTWVITSFAVSNAIALPLTGWLSRRF 78 I L + +F VL+ + NV+LP I+ + WV T+F ++ +I + G LS + Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 79 GEVKLFIWATLLFVLASFLCGVAQSMPELVLF-RVLQGVVAGPLYPMTQTLLIAVY-PPA 136 G +L ++ ++ S + V S L++ R +QG +P +++A Y P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVARYIPKE 135 Query: 137 KRGMALALLAMVTVVAPIAGPILGGWITDSYSWPWIFF---INVPIGLFAAAVVRQQMRT 193 RG A L+ + + GP +GG I W ++ I + F ++++++R Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRI 195 Query: 194 RPVVTSRQPMDYIGLLTLIVGVGALQVVLDKGNDLDWFESSFIVIGTLISVVFLAVFVIW 253 + D G++ + VG+ + F +S+ + ++SV+ +FV Sbjct: 196 ------KGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKH 239 Query: 254 ELTDRHPVVNLRLFVHRNFRIGTLVLVGGYAGFFGINLILPQWLQTQMGYTATWAGLAVA 313 P V+ L + F IG L + G ++P ++ + G + Sbjct: 240 IRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVII 299 Query: 314 PIGLLPVLMS-PFVGKYAHRFDLRVLA--GIAFLAIGTSCYMRAGFTNEVDFLHIALVQL 370 G + V++ G R + G+ FL++ ++ A F E + ++ + Sbjct: 300 FPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS---FLTASFLLETTSWFMTIIIV 356 Query: 371 FMGIGVALFFMPTLSILLSDLPPHQIADGSGLATFLRTLGGSF 413 F+ G++ +I+ S L + G L F L Sbjct: 357 FVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.9 bits (225), Expect = 5e-24 Identities = 75/258 (29%), Positives = 117/258 (45%), Gaps = 23/258 (8%) Query: 3 KVIVITGASRGIGAATALLAAQQGYRICINYHADDQAAEAMLAQVRALGAEAI---AVRA 59 K+ ITGA++GIG A A A QG I A D E + V +L AEA A A Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIA----AVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 60 DASVEDEVVRLFQCVDQELGPVTALVNNAGTIGQQSRVEDMSEFRLLKVMKTNVVGPILC 119 D + + +++E+GP+ LVN AG + + + +S+ N G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 120 AKHALLRMARRHGGQGGAIVNVSSMAARLGSPNEYVD-YAASKGALDTFTVGLAREVAGE 178 ++ M R + G+IV V S A G P + YA+SK A FT L E+A Sbjct: 124 SRSVSKYMMDR---RSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 179 GVRVNGVRPGYIHTGFH-----ALSGDPDRV----SKLEPGLPMGRGGQPEEVAEAILWL 229 +R N V PG T +G + + G+P+ + +P ++A+A+L+L Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 230 LSEKASYATGTFIDLSGG 247 +S +A + T + + GG Sbjct: 239 VSGQAGHITMHNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 50.6 bits (121), Expect = 1e-08 Identities = 28/127 (22%), Positives = 55/127 (43%), Gaps = 8/127 (6%) Query: 561 ILLVEDQTTLRLVIREVLEEHGFQVQEYEDGHTALHALSEGIRPTMLVVDIGLPGNIDGY 620 IL+ +D +R V+ + L G+ V+ + T ++ G ++V D+ +P + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPD-ENAF 63 Query: 621 QVTNACWAIDEHVPALFITGY---DGAIDNNRISGSPPIALLHKPFELTLLISKVEELLI 677 + +P L ++ AI + G+ L KPF+LT LI + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASE-KGA--YDYLPKPFDLTELIGIIGRALA 120 Query: 678 AARSKPA 684 + +P+ Sbjct: 121 EPKRRPS 127
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 28.0 bits (62), Expect = 0.031 Identities = 9/25 (36%), Positives = 14/25 (56%) Query: 65 FVNAHAPRPFSEPQPQAPASESTDV 89 + N AP + QP APA ++D+ Sbjct: 84 WENLSAPAKTEQTQPAAPAKPTSDI 108
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 28.3 bits (63), Expect = 0.043 Identities = 10/25 (40%), Positives = 14/25 (56%) Query: 202 HLAVDDFASRLGITSLQLNQLCRAL 226 L + + A + G+T LQLN C L Sbjct: 58 SLPITEVAEKTGLTFLQLNHYCEEL 82
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.0 bits (62), Expect = 0.012 Identities = 26/119 (21%), Positives = 43/119 (36%), Gaps = 33/119 (27%) Query: 37 SPGVAAPQPVDAPALSETPAGRWFADLPLQAQIQVSGVMAGSQGAVAIVSIDGGPARAVR 96 + + A Q + P P + ++GVMAG + +I I + Sbjct: 77 AGALDASQMSNLP--------------PSTLNLSLTGVMAGDDDSRSIAII-------SK 115 Query: 97 SGEELARGV---------RLVAIEGRGLVIERGGQRSRVEVPVLAQASFWGEAPQPSAN 146 E+ +RGV ++V+I +V++ G R EV L G P A Sbjct: 116 DNEQFSRGVNEEVPGYNAKIVSIRPDRVVLQYQG---RYEVLGLYSQEDSGSDGVPGAQ 171
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.1 bits (96), Expect = 4e-07 Identities = 23/65 (35%), Positives = 25/65 (38%), Gaps = 4/65 (6%) Query: 73 STWLGRNGIYLEDLYVTPQQRGDGAGRKLLRHIARE-AVENGCGRLEWSVLDWNEPAIGF 131 S W G +ED+ V R G G LL H A E A EN L D N A F Sbjct: 84 SNWNGY--ALIEDIAVAKDYRKKGVGTALL-HKAIEWAKENHFCGLMLETQDINISACHF 140 Query: 132 YRSLG 136 Y Sbjct: 141 YAKHH 145
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 119 bits (301), Expect = 3e-32 Identities = 55/366 (15%), Positives = 117/366 (31%), Gaps = 68/366 (18%) Query: 66 ISARVSGYVAEVAVADNAAVKTGDLLVRLDERDFRDRLRKAEAHLAVS------------ 113 I + V E+ V + +V+ GD+L++L K ++ L + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 114 --------------------------EAALQVQRMRLRAFAAEQDEQAHAIARADAERGG 147 + + + + ++ ++ + + AER Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 148 SRGEAQRAEADWQ-------RYQHLAQWQAASVQRMEQARATRIQAQAMQRAADAELARQ 200 R E + + L QA + + + ++A R ++L + Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 201 HARKAMLEQQGKQLEA--------ELLQRQADLDQARAEADLARSALADTEIRAPFDGVV 252 + +++ + + +L Q ++ E + IRAP V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 253 GQRKVRQQ-QYVTPGLPLLAVVPVAQAYVV-ANFKETQLAQMRPGQPVTLEVDTFGQ--- 307 Q KV + VT L+ +VP V A + + + GQ ++V+ F Sbjct: 339 QQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRY 398 Query: 308 -HWRGTVDSVSPGSGAVFALLPPDNATGNFTKIVQRFPVRIHLDPAGDDSPSLLPGMSVI 366 + G V +++ + D G ++ + G+ + L GM+V Sbjct: 399 GYLVGKVKNINLDA-------IEDQRLGLVFNVIISIEE--NCLSTGNKNIPLSSGMAVT 449 Query: 367 ATVDTR 372 A + T Sbjct: 450 AEIKTG 455
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 100 bits (250), Expect = 7e-25 Identities = 78/401 (19%), Positives = 166/401 (41%), Gaps = 17/401 (4%) Query: 23 FMAGMNVHVTSAALPEIEGALGASFEEGSWISTAYLVAEISMIPLTAWLVQVFSLRRVML 82 F + +N V + +LP+I +W++TA+++ + L ++R++L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 83 VGSAVFLVSSVSCAMAGS-LEAMISLRVIQGASGAVLIPLSMQLIITELPASRLALGMAL 141 G + SV + S +I R IQGA A L M ++ +P L Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 142 FSLSNSVAQAAGPSIGGWLTDMYSWRWIFLLQLPPGIALLAAVAWSIKGQAGDRSALRQA 201 ++ + GP+IGG + W ++ L+ + + V + +K + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP----MITIITVPFLMKLLKKEVRIKGHF 199 Query: 202 DWLGIAAMALGLGALQVVLEEGGRKDWFESRFIVGFSLVAMIALALFIQRQLWGTRPFIN 261 D GI M++G+ + F + + + F +V++++ +F++ T PF++ Sbjct: 200 DIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 262 LRLLGSYNFGVSSLAMAVFGAATFGLVFLVPNYLSLVQGYSASEIGKSLIAYGMVQLLL- 320 L + F + L + G V +VP + V S +EIG +I G + +++ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 321 APLLPRLMRWLNAKLLVASGFAIMALGCWLGSTLTVDSGSNVIIPSTVVRGIGQPLIMVA 380 + L+ ++ G +++ +L ++ +++ S + V G Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 381 LSVLAVKGLDKAQAGSASALISMLRNLGGALGTALLTQLVS 421 +S + L + +AG+ +L++ L G A++ L+S Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 62.2 bits (151), Expect = 2e-15 Identities = 36/141 (25%), Positives = 57/141 (40%), Gaps = 25/141 (17%) Query: 1 MKPSKGFTLIELLVVMAIIATLMTIAMPRYFNSLEASREATLRQSLAVLREALDHYYGDT 60 +GFTL+E++VV+ II L ++ +P + E + + + L ALD Y D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 GRYPDS---LDQLVEQRYL----RNTPVDPITER--RDAW----QLLPP----------- 96 YP + L+ LVE L N + +R D W L+ P Sbjct: 64 HHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSA 123 Query: 97 -PEGVAGGVADIKSGASGRAR 116 P+G G DI + + + Sbjct: 124 GPDGEMGTEDDITNWGLSKKK 144
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 47.6 bits (113), Expect = 1e-09 Identities = 28/110 (25%), Positives = 52/110 (47%), Gaps = 15/110 (13%) Query: 2 TPRQQGFSLIEVVLTLALLGLLASMAAPLTETVVRRGKEQQLREALYQIRDAIDAYKRAF 61 T +Q+GF+L+E+++ + ++G+LAS+ P + +Q+ + + +A+D YK Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK--- 60 Query: 62 DAGYIEKRLNASGYPPNLQVLVDGVRDVRSAKGAKFY----FLRRIPHDP 107 L+ YP Q L V A Y +++R+P DP Sbjct: 61 --------LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADP 102
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 147 bits (373), Expect = 1e-39 Identities = 77/345 (22%), Positives = 149/345 (43%), Gaps = 39/345 (11%) Query: 303 DERLNTLTMRDTPDAVRMAEKLLQSQDQSNPEVVLEVEVMEVATSRILDLGLQWPNTFGV 362 + N L + PD + E+++ D P+V++E + EV + L+LG+QW N Sbjct: 315 HGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAG 374 Query: 363 LTSDGKS----------VSVLDQLRGIDSSRIS------------ISPAPQAKINA--QD 398 +T S + ++ + SS S + A Sbjct: 375 MTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSS 434 Query: 399 KDINTLASPVIRVSNREQARIHIGQRVPIISATSVPSTQGPVITESVTYLDVGLKLEVQP 458 + LA+P I + +A ++GQ VP+++ + +T G I +V VG+KL+V+P Sbjct: 435 TKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQ--TTSGDNIFNTVERKTVGIKLKVKP 492 Query: 459 TVHLNNEVAIKVALEVSNATPLEATRQGTIPVQVDTRNAQTSLRLHDGETQVLAGLVRND 518 ++ + V +++ EVS+ ++ + +TR ++ + GET V+ GL+ Sbjct: 493 QINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKS 552 Query: 519 HNASGNKIPGLGDIPGLGRLFGSNKDDMSKSELVLAITPRIVRNLPYQSPSDMEFATGTE 578 + + +K+P LGDIP +G LF S +SK L+L I P ++R+ + A+ + Sbjct: 553 VSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRD-----RDEYRQASSGQ 607 Query: 579 ----SALQVRQLAQPVPASAVPT----EAPDDESQGAPRVEGQMA 615 + Q +Q + + + P ++ +V + Sbjct: 608 YTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFRQVSAAID 652 Score = 41.8 bits (98), Expect = 7e-06 Identities = 30/185 (16%), Positives = 63/185 (34%), Gaps = 26/185 (14%) Query: 189 TLEFRDADLKTIFEVLAQVAGINFIFDKDLRPDMKATIFVR---EVRIEDAVALL---LE 242 + F+ D++ +++ I D P ++ TI VR + E L+ Sbjct: 31 SASFKGTDIQEFINTVSKNLNKTVIID----PSVRGTITVRSYDMLNEEQYYQFFLSVLD 86 Query: 243 QNQLRQKIVNDNTLLVYPDSPQKTKDY-----------QELVMRTFYLTSIDANTALNMV 291 +N+ L V KT E+V R LT++ A ++ Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 292 KTMLKT----RDVFVDERLNTLTMRDTPDAVRMAEKLLQSQDQSNPEVVLEVEVMEVATS 347 + + V + N L M ++ +++ D + V+ V + + + Sbjct: 147 RQLNDNAGVGSVVHYEPS-NVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAA 205 Query: 348 RILDL 352 ++ L Sbjct: 206 DVVKL 210
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.2 bits (177), Expect = 2e-17 Identities = 30/136 (22%), Positives = 52/136 (38%), Gaps = 5/136 (3%) Query: 3 RVLVVDDEQTLAQNLQAYLQAQGLEVHLAHDGTTGIELAENLAPDVIVLDYRLPDMEGFQ 62 +LV DD+ + L L G +V + + T D++V D +PD F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 63 VLETVR-RNRSCHFVLITAHPTAEVRERAAELGVTHVLFKPFPL----MELARAVFDLMG 117 +L ++ ++++A T +A+E G L KPF L + RA+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 118 IERQRRSTDQPAAGFV 133 + Q V Sbjct: 125 RPSKLEDDSQDGMPLV 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 4e-13 Identities = 23/114 (20%), Positives = 48/114 (42%), Gaps = 1/114 (0%) Query: 2 TSVLLVDDHHIVRLAVRMLLERERFTVVGETGKGKEAARLAEQTKADVVILDIGLPDLDG 61 ++L+ DD +R + L R + V T R D+V+ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 MEEIKRLKLIDPPPRIMALTGQPADLYVRRCMDAGISAFVNKDEDLDALVFALK 115 + + R+K P ++ ++ Q + + + G ++ K DL L+ + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.5 bits (152), Expect = 5e-12 Identities = 31/167 (18%), Positives = 61/167 (36%), Gaps = 14/167 (8%) Query: 847 RVLVVDDYPANLLLLDKQLRSLGHQVTLADHGKTALALWQVGRFDVVITDCSMPVMDGHT 906 +LV DD A +L++ L G+ V + + T G D+V+TD MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 907 LARSIRAEEREARSPACRIIGVTANAQAEERQRCLDSGMDECLFKPI----GLQALRACL 962 L I+ P ++ ++A + + G + L KP + + L Sbjct: 65 LLPRIK-----KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 963 PLATTLPDQVDTMPRPSGFDLAELRHLTQDDSQLTRRLLEQLAQSSA 1009 P +++ + + + + R+L +L Q+ Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQE-----IYRVLARLMQTDL 161
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 93.6 bits (232), Expect = 6e-25 Identities = 64/257 (24%), Positives = 101/257 (39%), Gaps = 14/257 (5%) Query: 5 LQGARVVVSGGTRGIGRAIVECFLAEGAQVA---FCARDEAGVRQAEAELGDLACGRAVD 61 ++G ++G +GIG A+ ++GA +A + V + A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 62 ITNAAQVDGWIAAAAERMGGIDIVVPNVS-----ALAHGSEAPIWRQAFETDLLGTVGMV 116 + ++A +D A MG IDI+V NV+ L H W F + G Sbjct: 66 VRDSAAIDEITARIEREMGPIDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 117 TAALPWLKASAQAAVILISSVSGRELSSFDEPYGVLKAALNHYGKTLSARHAGEGIRVNC 176 + ++ +++ + S + Y KAA + K L A IR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 177 VSPGNVYFADGVWGRIEREQPEAFARSLAAN-----PLGRMARPEEVARAAVFLASPAAS 231 VSPG+ + E + PL ++A+P ++A A +FL S A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 232 FISGTNLLVDGGLTRGV 248 I+ NL VDGG T GV Sbjct: 245 HITMHNLCVDGGATLGV 261
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.9 bits (75), Expect = 0.003 Identities = 24/94 (25%), Positives = 37/94 (39%), Gaps = 7/94 (7%) Query: 81 GAIVFGRLGDMIGRKYTFLITIVIMGLSTAVVGLLPSYATIGVAAPVILITLRLLQGLAL 140 G V+G+L D +G K L I+I + + +G + +LI R +QG Sbjct: 65 GTAVYGKLSDQLGIKRLLLFGIIINCFGSVI-------GFVGHSFFSLLIMARFIQGAGA 117 Query: 141 GGEYGGAATYVAEHAPKGKRGFFTAWIQTTATLG 174 VA + PK RG I + +G Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMG 151 Score = 29.1 bits (65), Expect = 0.048 Identities = 13/49 (26%), Positives = 24/49 (48%) Query: 282 TLKIDPQTANLLIAGSLLIGTPFFIVFGSLSDRIGRKKIIMAGCIIAAL 330 P + N + +L + V+G LSD++G K++++ G II Sbjct: 43 DFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCF 91
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.006 Identities = 18/105 (17%), Positives = 28/105 (26%), Gaps = 6/105 (5%) Query: 124 ARSLARIRALDEQRLPATTLAQEAALSISQLERLFSGSLGLSVRRLVLWQRLRQALRQAL 183 R R+++ +LP L E E L + WQ + L Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVS-EEEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Query: 184 AGASLTEAAMAAGFADSAHLSRSLRQQFGIRASDALRHLRSDALI 228 + A +LSR + + D L I Sbjct: 210 DKKRAERLTVLARINRYENLSRVEKSRL-----DDFSSLLHKQAI 249
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.4 bits (86), Expect = 5e-05 Identities = 35/189 (18%), Positives = 68/189 (35%), Gaps = 3/189 (1%) Query: 81 EEGQARIDAAEAAAEARCAAMQAELQLAQRDLASALRQVETLSGALRAESERLATCQASL 140 E +A + A +A E + + + L + L Sbjct: 217 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFS 276 Query: 141 QTEQLRSAGLSQSQGELQARLADKDEQLRASFEQRQQEQRRNETQVR---QLQGQLQTLQ 197 + + L + L+A AD + Q + RQ +R + QL+ + Q L+ Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLE 336 Query: 198 QGAIARQDEVTRLHRDNERLLAEQRQAMAQSRLLDEQLQQRDAQVQGLRAILAQAQGAND 257 + + L RD + ++Q A+ + L+EQ + +A Q LR L ++ A Sbjct: 337 EQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKK 396 Query: 258 EMRRQLATR 266 ++ + L Sbjct: 397 QVEKALEEA 405
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 62/380 (16%), Positives = 120/380 (31%), Gaps = 45/380 (11%) Query: 26 HSQQSVRQQWLAILSVAVGAFALVTSEFLPVGVLNDVAADLGISAGQAGLMVTLPGI-MA 84 +SQ ++R + I + F+++ L V L D+A D + T + + Sbjct: 5 YSQSNLRHNQILIWLCILSFFSVLNEMVLNVS-LPDIANDFNKPPASTNWVNTAFMLTFS 63 Query: 85 ALAAPLLSVGIGALDRRYLLIALTLIMIVANAVVAYATDFGLLLFGRVLLGISIGGFWAT 144 A + +R LL + + + + F LL+ R + G F A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 145 AIALSGRLAPKGVGVAQATSIIMVGVTLATVLGVPVGTWLSGLMGWRMTFLVTALVGVPV 204 + + R PK +A +I V + +G +G ++ + W L+ + + V Sbjct: 124 VMVVVARYIPKE-NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITV 182 Query: 205 LLAQVLLLPRLNPEKAIRISDLPALFVNPQARVGLIAVLLIGLAHFAAYTYVAPFFKHNA 264 LL + + I + + V + I + +++ F KH Sbjct: 183 PFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLI-FVKHIR 241 Query: 265 GFDGPMIGSLLLLYGVAGVLGNVFAGFAANQSVRYTLMLVALMIGIGTALFPYFATSLTG 324 P + L + V G +V + +V M+ L S+ Sbjct: 242 KVTDPFVD--PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI- 298 Query: 325 AAMLIALWGFAFGAFPACASIWMFVVAPKDVERGMPLFVAMFQVIIALGSFFGGRIVDQM 384 +F VII + GG +VD+ Sbjct: 299 ------------------------------------IFPGTMSVIIF--GYIGGILVDRR 320 Query: 385 GSAVLFSLATALVGCGFVTV 404 G + ++ + F+T Sbjct: 321 GPLYVLNIGVTFLSVSFLTA 340
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.002 Identities = 21/130 (16%), Positives = 43/130 (33%), Gaps = 8/130 (6%) Query: 228 QQSTAQAERAAQELLRLKQQRQRQVQALQRQRENFERHQACAGRRAKQANQAQILLDRQQ 287 + + AE + QE +++ Q + + RE A + +AN + + Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNRE-----VAKEAKSNVKANTQTNEVAQSG 1089 Query: 288 QRSQATAGRQRRELRDAKAALDEQVRQAARQVEREVPIVLHAPTPQRHTGREVLALEGLC 347 T Q E ++ E+ + + +EVP V +P++ V Sbjct: 1090 SE---TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 348 LPRGTTDALD 357 T + Sbjct: 1147 RENDPTVNIK 1156
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 4e-17 Identities = 29/132 (21%), Positives = 53/132 (40%) Query: 2 PRVLTIEDDAVTAQEIVAELSSHGLEVDWADNGREGLAKAIAGGYDLITLDRMLPEVDGL 61 +L +DDA + LS G +V N AG DL+ D ++P+ + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 TIVTTLRNLKIATPILMISALSDVDERVRGLRAGGDDYLTKPFASDEMAARVEVLLRRNS 121 ++ ++ + P+L++SA + ++ G DYL KPF E+ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 VPMTQTRLQVAD 133 ++ D Sbjct: 124 RRPSKLEDDSQD 135
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 4/47 (8%) Query: 362 LVGNAIKF----TPQGGQVRMVASEDDQGVHIAVEDSGPGIPADERE 404 LV N IK PQGG++ + ++D+ V + VE++G + +E Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE 309
>adhesinb#Adhesin B signature. Length = 310 Score = 41.8 bits (98), Expect = 2e-06 Identities = 28/168 (16%), Positives = 63/168 (37%), Gaps = 13/168 (7%) Query: 133 WLNPTNLGRMADVVANDLERLSPADKAKIQGNLAGLKRQMLELTANSQTRLAEV--DNLT 190 WLN N A +A L PA+K + NL ++ L ++ + + + Sbjct: 142 WLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKM 201 Query: 191 VVSLSERLGYLASGLNLDVVE-QPLPADDKWDQAMLKALGENLKAQDVALVLHHRQPDAK 249 +V+ Y + N+ + +++ +K L E L+ V + D + Sbjct: 202 IVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDR 261 Query: 250 VAEMIAA-SGAKL---LVVDSDPDDTVAG------LKASVEQVVKALG 287 + ++ + + + DS + G +K ++E++ + L Sbjct: 262 PMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYNLEKIAEGLS 309
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 33.8 bits (77), Expect = 3e-04 Identities = 38/185 (20%), Positives = 64/185 (34%), Gaps = 26/185 (14%) Query: 3 IDPRKATLLVIDIQEKLIGAMSD----PEGTAARARWLLAATAELKLPTVISEQ------ 52 DP +A LL+ D+Q + A + +A R L +L +P V + Q Sbjct: 26 PDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNP 85 Query: 53 ---------YPKGLGHTLA---VLKAAAPAAEIVE--KLHFSCVAAECLPPSLLD--REQ 96 + GL ++ AP + + K +S L + R+Q Sbjct: 86 DDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQ 145 Query: 97 VIVCGMETHVCVLQTVLGLRALGKQVFVVEDACDSRTPASKAAGLARMRDAGAQVVTREM 156 +I+ G+ H+ L T + F V DA + L A V + Sbjct: 146 LIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDS 205 Query: 157 VLFEL 161 +L +L Sbjct: 206 LLDQL 210
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 807 bits (2085), Expect = 0.0 Identities = 314/1029 (30%), Positives = 532/1029 (51%), Gaps = 29/1029 (2%) Query: 5 DLFVRRPVLALVVSTLILLLGLLSLLQLPIRQYPLLESSTITVTTEYPGAPAELMQGFVT 64 + F+RRP+ A V++ ++++ G L++LQLP+ QYP + ++V+ YPGA A+ +Q VT Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPIAQAVSSVEGIDYLSSSSVQ-GRSLVTVRMELNRDSTQALTEVMAKVNQVRFRLPERA 123 Q I Q ++ ++ + Y+SS+S G +T+ + D A +V K+ LP+ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 YDPVIERSAGESTAVAYIGFAS--PSLPIPAMTDYLTRVVEPLLSTIEGVAKVQVFGGQT 181 I S+ + GF S P ++DY+ V+ LS + GV VQ+FG Q Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ- 181 Query: 182 LSMRLWIDPARLAARGLTAADVAEAVRRNNYQAAPGKV------KGQYVIANIRVDTDLT 235 +MR+W+D L LT DV ++ N Q A G++ GQ + A+I T Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 SVGDFRELVIRNDGNG-LVRIRDIGTVELGAASAETSASMDGVPAVHLGLFATPGGNPLV 294 + +F ++ +R + +G +VR++D+ VELG + A ++G PA LG+ G N L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 IVEGIRQLLPQIRQTLPPDVKAELAFETARFIQASIDEVTKTLLEALAIVVVVIYLCLGS 354 + I+ L +++ P +K ++T F+Q SI EV KTL EA+ +V +V+YL L + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 LRTVLIPVVTIPLSMLGAAALMLAFGFSINLLTLLAMVLAVGLVVDDAIVVVENVHRHI- 413 +R LIP + +P+ +LG A++ AFG+SIN LT+ MVLA+GL+VDDAIVVVENV R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 414 EEGRTPVAAALIGAREVAGPVIAMTITLAAVYAPIGMMGGLTGALFREFALTLAGAVVVS 473 E+ P A ++ G ++ + + L+AV+ P+ GG TGA++R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GVVALTLSPVMSSFLLDARQSE-----GRMAHAANRFFDWLAERYAHVLGFSLKHRWISV 528 +VAL L+P + + LL +E G N FD Y + +G L + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 GFALLVLVSLPLLYSLPQRELAPTEDQAGLLTAIKAPQHANLAYVERFADKLDAVYRTLP 588 L++ + +L+ P EDQ LT I+ P A ++ D++ Y Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 589 E------TVSTWIINGSDGIASGIGGINLQPWDERARN---ASQIQLDLQAAVNDVEGTS 639 + +G+ ++L+PW+ER + A + + + + Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 640 IFAFQLPA--LPGSTGGLPVQMVLRSSQDYRVLFDTMEQVKAKARQS-GLFAVVDSDLDY 696 + F +PA G+ G +++ ++ + L Q+ A Q V + Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 697 NNPVVQVRVDRAKANSMGIRMQDIGESLAVLVGENYLNRFGLDGRSYDVIAQSPRDQRLT 756 + ++ VD+ KA ++G+ + DI ++++ +G Y+N F GR + Q+ R+ Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 757 PQALTRQYVRSEEGRLVPLSTVVQVSEQVEPNRLTQFNQQNAATFQGIPAAGVTLGDTVA 816 P+ + + YVRS G +VP S RL ++N + QG A G + GD +A Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 817 FLEQVAAELPVGFSIDWQSDARQYQQEGNALMLAFLAAVVVIYLVLAAQYESLVDPLIIL 876 +E +A++LP G DW + Q + GN + VV++L LAA YES P+ ++ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 877 ITVPLSISGALLPLALGVATVNIYTQIGLVTLIGLISKHGILMVEFANTLQAEQHLDRRT 936 + VPL I G LL L ++Y +GL+T IGL +K+ IL+VEFA L ++ Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 937 AIGKAAQIRLRPILMTTAAMVVGLIPLLFASGAGAASRFGLGVVIVTGMLVGTLFTLFVL 996 A A ++RLRPILMT+ A ++G++PL ++GAG+ ++ +G+ ++ GM+ TL +F + Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 997 PTIYSLLAR 1005 P + ++ R Sbjct: 1022 PVFFVVIRR 1030
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 50.6 bits (121), Expect = 5e-09 Identities = 22/141 (15%), Positives = 64/141 (45%), Gaps = 7/141 (4%) Query: 104 QAERLRLKAQLDNARTNHRRVKDLLRENAATQEQLDNALAARDMAQGELARTEAVIAQKA 163 +++ ++++++ +A+ ++ V L + ++L + ELA+ E Sbjct: 272 KSQLEQIESEILSAKEEYQLVTQLFKNEIL--DKLRQTTDNIGLLTLELAKNEERQQASV 329 Query: 164 VRAPFDGRLGIRRVN-QGQYLNVGDPVVSLI-DTRSLYVNFSLEEQLSAQLRPGQPVEVR 221 +RAP ++ +V+ +G + + ++ ++ + +L V ++ + + GQ ++ Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 222 LDAFPDT---PFTAHITAIDP 239 ++AFP T + I+ Sbjct: 390 VEAFPYTRYGYLVGKVKNINL 410 Score = 39.0 bits (91), Expect = 2e-05 Identities = 22/95 (23%), Positives = 44/95 (46%), Gaps = 3/95 (3%) Query: 70 VSAEIGGRVTAINFTSGQQVRKGDVLVTLNDAPEQAERLRLKAQLDNARTNHRR---VKD 126 + V I G+ VRKGDVL+ L +A+ L+ ++ L AR R + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 127 LLRENAATQEQLDNALAARDMAQGELARTEAVIAQ 161 + N + +L + +++++ E+ R ++I + Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 50.6 bits (121), Expect = 5e-09 Identities = 34/155 (21%), Positives = 65/155 (41%), Gaps = 2/155 (1%) Query: 42 LSDIGRSFEMTTAQVGLMLTIYAWVVALASLPMMLMTRNIERRRLLLIVFLVFIASHLLS 101 L DI F A + T + ++ + ++ + +RLLL ++ ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 102 WLSQSFAMLLV-SRIGIALAHAVFWAITASLAVRVAPPGQQAKALGLLATGTTLAMVMGI 160 ++ SF LL+ +R A F A+ + R P + KA GL+ + + +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 161 PLGRVVGEALGWRITFLCIAGVALATMLCLMKSLP 195 +G ++ + W L I + + T+ LMK L Sbjct: 157 AIGGMIAHYIHWSYLLL-IPMITIITVPFLMKLLK 190
>PF05860#haemagglutination activity domain. Length = 117 Score = 60.6 bits (147), Expect = 1e-12 Identities = 20/99 (20%), Positives = 41/99 (41%), Gaps = 8/99 (8%) Query: 155 QQSQVGGRTQVLIE---QTADKAILNWETFNVGRDTTVKFDQ-QAQWAVLNRVNDPNARP 210 + +IE Q +++ F+V T F+ +++RV + Sbjct: 12 NSNITTEGNTRIIERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRVTGGS--V 69 Query: 211 SQIQGQIEAQGT--VMLVNRNGVVFNGSSQVNVRNLVAA 247 S I G I A T + L+N NG++F ++++++ Sbjct: 70 SNIDGLIRANATANLFLINPNGIIFGQNARLDIGGSFVG 108
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.002 Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 31 VVAIIGRSGSGKSTFLRTLNGLESISDGVIEV 62 V + G G GKST + TL GL+ SD ++ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 74.3 bits (182), Expect = 2e-18 Identities = 33/167 (19%), Positives = 63/167 (37%), Gaps = 8/167 (4%) Query: 15 RSRKNNPEKTRENILQAAITEFVQQGLAGARVDAIAERTATSKRMIYYYFGSKEQLYVEC 74 R K ++TR++IL A+ F QQG++ + IA+ ++ IY++F K L+ E Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 75 LVKLYGDIRKTEHSLDLDSLSPEQAIQRLVE-----FTFDHHADNVD-FVRIVCTENIHY 128 +I E L+ + P + L E + + I+ + Sbjct: 63 WELSESNIG--ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 129 GEYVKQSPVIREMSSMVLDALGKILARGVEQGVFRPGIEVIDLHMLM 175 GE R + D + + L +E + + ++M Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 32.0 bits (72), Expect = 0.008 Identities = 28/78 (35%), Positives = 34/78 (43%), Gaps = 18/78 (23%) Query: 491 ASLRLPLNISENRNTAIAHAL--DSYRGSGVHHVAFDCDDIFAEVARAKEAGVPLLEIPL 548 AS+ LPL IS R A A AL S G+G V + C +AR+ GVP Sbjct: 36 ASITLPLPISAERGFAPALALHYSSGGGNGPFGVGWSCA--TMSIARSTSHGVP------ 87 Query: 549 NYYDDLAARFEFDDEFLS 566 Y+D DEFL Sbjct: 88 -QYND-------SDEFLG 97
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 2e-04 Identities = 42/210 (20%), Positives = 74/210 (35%), Gaps = 32/210 (15%) Query: 239 VLVMFMALMNVIPVVATI---FGAAYAVQPAYGIGFDKSVYLWIPVVGNIVAVLVIPFVG 295 V + + + ++PV+ + + V YGI + + ++ P +G Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGI---------LLALYALMQFACAPVLG 64 Query: 296 NLSDRIGRRPTMIAGCLGSGLLAFVYLYAISIQNVPLAFAASIL--MWGMVYQGYNAVFP 353 LSDR GRRP ++ G+ + + A + + + I+ + G A Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATA---PFLWVLYIGRIVAGITGATGAVAGAYIA 121 Query: 354 SFYPELFHTRYRVSAMAIAQNIGTMITAMLPALFAAVAPPGSEHIWLVVGGLAFLVTCVC 413 R+ M+ G + +L L +P + GL FL C Sbjct: 122 DITDGDERARH-FGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCF- 179 Query: 414 AFAAYLAPETHRLAMEDLGNPQARPMEREA 443 L PE+H + RP+ REA Sbjct: 180 -----LLPESH--------KGERRPLRREA 196 Score = 32.5 bits (74), Expect = 0.003 Identities = 57/350 (16%), Positives = 122/350 (34%), Gaps = 33/350 (9%) Query: 69 ACVLGHWGDTRGRKNVLLLCMFLMGLSTMAVGLLPTYHDIGLLAPALLVVLRLIQGFAVA 128 A VLG D GR+ VLL+ + + + P +L + R++ G A Sbjct: 60 APVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL--------WVLYIGRIVAGITGA 111 Query: 129 GEISGASSMIMEHAPFGRRGYYASYTLQGVQAGQVMAAAVFLPLAYFMPSEAFNEWGWRI 188 + A + I + R + + G V + + F P Sbjct: 112 -TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSP---------HA 161 Query: 189 PFLMSAVVLIAGFIIRKEVHETPAFVQEEKLDKVAKSPIGEAFRHSWKHMVLVMFMALMN 248 PF +A + F+ + + L + A +P +FR + V+ MA+ Sbjct: 162 PFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNP-LASFRWARGMTVVAALMAVFF 220 Query: 249 VIPVVATIFGAAYAVQPAYGIGFD-KSVYLWIPVVGNIVAVLVIPFVGNLSDRIGRRPTM 307 ++ +V + A + + +D ++ + + G + ++ G ++ R+G R + Sbjct: 221 IMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL 280 Query: 308 IAGCLGSGLLAFVYLYAISIQNVPLAFAASILMWGM-----VYQGYNAVFPSFYPELFHT 362 + G + G Y+ +AF +L+ Q + + Sbjct: 281 MLGMIADGT---GYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQ 337 Query: 363 RYRVSAMAIAQNIGTMITAMLPALFAAVAPPGSEHIWLVVGGLAFLVTCV 412 + ++ +G ++ A++AA + W+ G A + C+ Sbjct: 338 GSLAALTSLTSIVGPLLFT---AIYAASITTWNGWAWIA--GAALYLLCL 382
>PF05860#haemagglutination activity domain. Length = 117 Score = 82.5 bits (204), Expect = 9e-21 Identities = 23/136 (16%), Positives = 43/136 (31%), Gaps = 21/136 (15%) Query: 37 VVVAPGPGGTAQLQTQGGVPIVNIVAPNGAGLSHNQFLDYNVDRQGLVLNNALQAGHSQL 96 + + + T+G I+ G+ L H+ F +++V G N Sbjct: 3 ITPDTTLPINSNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFN--------- 52 Query: 97 AGELAANPQFQGQAASVILNEVVSRNASAINGAQEIFGRAADYVLANPNGISVNGASFIN 156 I++ V + S I+G A + L NPNGI + ++ Sbjct: 53 ----------NPTNIQNIISRVTGGSVSNIDGLIRANATA-NLFLINPNGIIFGQNARLD 101 Query: 157 APNASLVVGRPELDAG 172 + + L Sbjct: 102 IGGSFVGSTANRLKFA 117
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 43.7 bits (103), Expect = 1e-06 Identities = 63/358 (17%), Positives = 121/358 (33%), Gaps = 56/358 (15%) Query: 68 LGGLVFGHFGDRVGRQKVLVTTLLLMGLSTFLIGCLPGHASLGVAAPILLVLLRLVQGFA 127 +G V+G D++G ++ LLL G+ G + G + LL++ R +QG Sbjct: 64 IGTAVYGKLSDQLGIKR-----LLLFGIIINCFGSVIGFVGHSFFS--LLIMARFIQGAG 116 Query: 128 AGG----EWGGAALFGIESAPPGRRGLWGSFTSMGIGVGGILGAAV-------------- 169 A A + + GL GS +MG GVG +G + Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 170 ----------FALVSAAFDDNLVDFAWRIPFWLGGTLVLIGLYARLKTPLAASTVKPVRA 219 L D I +G ++ + + L S + + Sbjct: 177 ITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF 236 Query: 220 PLAQALRQRP------------RQLLLCTGIAFGYCTIAYIGSTFFLTYATQAGYGSTEA 267 P +LC GI FG G + Y + + + A Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFG----TVAGFVSMVPYMMKDVHQLSTA 292 Query: 268 LM---FDLTLSVAIVLSAPLFGHLSDRLGRRVVMVFGALVMALGLFVFFALVDMRHFGIA 324 + ++++++ + G L DR G V+ G +++ L++ + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMT 352 Query: 325 LVAYSLVGALMGATQGPIPAFLGEQFPREMRYSGISASYQVGAALGGGTASSIATAIL 382 ++ ++G L T+ I + ++ +G+S + L GT +I +L Sbjct: 353 IIIVFVLGGL-SFTKTVISTIVSSSLKQQEAGAGMSL-LNFTSFLSEGTGIAIVGGLL 408
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.9 bits (78), Expect = 0.002 Identities = 17/39 (43%), Positives = 24/39 (61%) Query: 515 YTLNAARAMRLERQIGSLRAGKQADMIVLDRDVFSVAPQ 553 YT+N A A L +IGSL GK+AD+++ + F V P Sbjct: 409 YTINPAIAHGLSHEIGSLEVGKRADLVLWNPAFFGVKPD 447
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.8 bits (72), Expect = 5e-04 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 4/51 (7%) Query: 87 VAPEARGQGLAERLIEGVCEHARSNAVTTLYLHTHDQDA----YYAKRGWT 133 VA + R +G+ L+ E A+ N L L T D + +YAK + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 2e-05 Identities = 59/289 (20%), Positives = 105/289 (36%), Gaps = 61/289 (21%) Query: 86 FFGALGDRYGRQKVLAATIVIMSLSTFAIGLIPSYASIGIWAPILLLLAKMAQGFSVGGE 145 GAL DR+GR+ VL ++ ++ + P +W +L + ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 146 YTGASIFVAEYAPDRKR----GFLGSWLDFGSIAGFVLGAGVVVLISTVLGEEQFLEWGW 201 A ++A+ +R GF+ + FG +AG VLG ++G + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG--------LMG-----GFSP 159 Query: 202 RLPFFLALPLGLIGLYLRHALEETPAFQQHVDKLEQGDREGLASGPKVSFKEVATQHWRS 261 PFF A L + L K E+ A P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 262 LLTCIGVVIATNVTYYML-------LTYMPSYLSHNLHYS-EDHGVLIIIAIMVGMLFVQ 313 +T VV A ++++ + H+ G+ + ++ L Sbjct: 208 GMT---VVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQA 264 Query: 314 PIIGLLSDKWGRKPFIIIG----SAGLFLLA--------IPAFMLITSG 350 I G ++ + G + +++G G LLA P +L+ SG Sbjct: 265 MITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG 313 Score = 38.3 bits (89), Expect = 6e-05 Identities = 34/169 (20%), Positives = 75/169 (44%), Gaps = 16/169 (9%) Query: 287 LSHNLHYSEDHGVLI-IIAIMVGMLFVQPIIGLLSDKWGRKPFIIIGSAGLFLLAIPAFM 345 L H+ + +G+L+ + A+M P++G LSD++GR+P +++ L A+ + Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLV---SLAGAAVDYAI 89 Query: 346 LITSGKLAVIFAGLLILAVLLNFFIGVMASTLPAMFPTHIR---YSALASAFNISVLIAG 402 + T+ L V++ G ++ A + V + + + R + +++ F ++AG Sbjct: 90 MATAPFLWVLYIGRIV-AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 403 LTPTLAAWLVETTDNLYMPAYYLMVIAVVGLLTG-LTMKETANRPLRGA 450 P L + + + P + + + LTG + E+ R Sbjct: 148 --PVLGGLMGGFS--PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPL 192
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.9 bits (127), Expect = 1e-10 Identities = 26/124 (20%), Positives = 53/124 (42%), Gaps = 2/124 (1%) Query: 3 RILLIDDTEKKVGRLKAALIEAGFEVIEAGSLSIDLPACVETVHPDVVLIDTESPGRDVM 62 IL+ DD L AL AG++V + + L + D+V+ D P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAA-TLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 EQVVLVSRDRPR-PIVLFTDEHDPGVMRQAIQAGVSAYIVEGIQATRLQPILDVAMARFE 121 + + + + RP P+++ + ++ +A + G Y+ + T L I+ A+A + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 SDQA 125 + Sbjct: 124 RRPS 127
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 42.9 bits (101), Expect = 1e-06 Identities = 90/454 (19%), Positives = 156/454 (34%), Gaps = 83/454 (18%) Query: 1 MNTSFWKSG--HVPTLFAAFLYFDLSFMVWYLLGPLAVQIAADLQLSAQQRGLMVATPIL 58 MNTS+ +S H L + S + +L IA D + +L Sbjct: 1 MNTSYSQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFML 60 Query: 59 AGAVLRFAMGLLVDRLSPKTAGLIGQVIVIVALACAWQLGVHSYEQALLLGVFL-GFAGA 117 ++ G L D+L K L G I+I HS+ L++ F+ G A Sbjct: 61 TFSIGTAVYGKLSDQLGIKRLLLFG--IIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA 118 Query: 118 SF-AVSLPLASQWYPPQHQGKAMG-IAGAGNSGTVFAALLAPALAADFGWNNVFGFALLP 175 +F A+ + + +++ P +++GKA G I G + +A W + LL Sbjct: 119 AFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW----SYLLLI 174 Query: 176 LLLTLVLFALLARNAPQRPRPKAMADYLKAL------------GDRDSWWFMFFYSVTFG 223 ++T++ L + + R K D + S F+ ++F Sbjct: 175 PMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 224 GFI------------------------------------GLASALPGYFSDQYGLSPVTA 247 F+ G S +P D + LS Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 248 GYYTAACVFAGSL----MRPLGGALADRFGGIRTLLAMYGVAAVCIAAVGFNLPSAAAAL 303 G + +F G++ +GG L DR G + L +V F L + + + Sbjct: 295 G---SVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFM 351 Query: 304 ALFVSAMLG-LGAGNGAVFQLVPQRFR-QEIGVMTGLI------GMAGGIG--GFLLAAG 353 + + +LG L + +V + QE G L+ GI G LL+ Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411 Query: 354 L-------GTIKQHTGDYQLGLWLFASLGLLAWV 380 L + Q T Y L LF+ + +++W+ Sbjct: 412 LLDQRLLPMEVDQSTYLYSNLLLLFSGIIVISWL 445
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 39.7 bits (92), Expect = 3e-05 Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 7/111 (6%) Query: 358 VARQLLQAVGVLHRRNLLHRDIKPENLHYG-SDGQLRLLDFGLAYCPGLCEDPPHAVPGT 416 +A +LL L + ++H DIKP N+ + + G+ ++D GL G E P T Sbjct: 250 IAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSG--EQPKGF---T 304 Query: 417 PSFLAPEAFDG-LPPAPRQDLYAVGVTLYHLLTGHYPYGEVEAFQRPRFGT 466 SF APE G L + + D++ V TL H + G E++ Q RF T Sbjct: 305 ESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFIT 355
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 142 bits (360), Expect = 9e-42 Identities = 78/328 (23%), Positives = 130/328 (39%), Gaps = 57/328 (17%) Query: 39 QYYDSERNFKNDGTNPGVRLGYFLTDDVSLDLGYNET--HNARGEVFNKDIKGSKTKLDA 96 + ++ + G GY + V ++GY+ +G V N K +L A Sbjct: 43 GFINNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTA 102 Query: 97 TYHFGTVGDALRPYVSAGFAH-ESLGQATRNGRDHSTFAN--VGAGAKWYITDMFFARAG 153 + + D L Y G + ++ G++H T + G ++ IT R Sbjct: 103 KLGY-PITDDLDIYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLE 161 Query: 154 VEAMYNIDNGNT----EWGPTVGLGLNFGGSGGQKA---APAPAPVAEVCSDSDNDGVCD 206 + NI + +T + LG+++ G+ A APAPAP EV + Sbjct: 162 YQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH------- 214 Query: 207 NVDKCPDTPANVTVDADGCPAVAEVVRVELDVKFDFDKSVVKPNSYGDIKNLADFMKQY- 265 ++ DV F+F+K+ +KP + L + Sbjct: 215 -------------------------FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLD 249 Query: 266 -PQTTTTVEGHTDSVGPDAYNQKLSERRANAVKQVLTQQYGIESSRVDSVGYGETRPVAD 324 + V G+TD +G DAYNQ LSERRA +V L + GI + ++ + G GE+ PV Sbjct: 250 PKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISK-GIPADKISARGMGESNPVTG 308 Query: 325 NATEAGR---------AVNRRVEAQVEA 343 N + + A +RRVE +V+ Sbjct: 309 NTCDNVKQRAALIDCLAPDRRVEIEVKG 336
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.2 bits (96), Expect = 6e-06 Identities = 25/102 (24%), Positives = 37/102 (36%), Gaps = 15/102 (14%) Query: 296 PKPLPTAPEQAAAKVEYQPLPATAVGGKTAAELRAEEAAKPA--QAPAAEPAQ------- 346 K A +A AK + L K A EL A K + Q P A+P Sbjct: 429 EKAELQAKLEAEAKALKEKLA------KQAEELAKLRAGKASDSQTPDAKPGNKAVPGKG 482 Query: 347 ATAQAATGSFDKIHTVIQERCTVCHSAKPTSPLFSAAPAGVM 388 QA T + + + + + + +P F+AA VM Sbjct: 483 QAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVM 524
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 34.6 bits (79), Expect = 3e-04 Identities = 34/144 (23%), Positives = 63/144 (43%), Gaps = 14/144 (9%) Query: 19 PAHAGEWLQWHGESLSYLYGKDFKVNPDIQQTITFEHAN--KWKYGDTFLFVDKIFYNGK 76 P + +W WH +S++ + + P I+ E+ K + D + ++D + G Sbjct: 28 PQYLSDW--WH-QSVNVVGSYHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYIDAPVFFGG 84 Query: 77 ADPGKGV----TTYYGEFSPRLSFGKIFERNLAFGPIKDVLLAMTYERGEGDNEA----- 127 KG+ + + E PR S K+ +L+FGP K+ A Y G N++ Sbjct: 85 NSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNDSQEQST 144 Query: 128 YLIGPGFDLNVPGFNYFTLNFYVR 151 + +G G D++ +LN Y + Sbjct: 145 WYMGLGTDIDTGLPMSLSLNVYAK 168
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 33.1 bits (75), Expect = 0.001 Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 17/137 (12%) Query: 6 SLILAGGLLACGASQAGD---------LLQWQNNSLTYLWGKNFKVNPEIQQTVTFEHAD 56 +L+ AG ++A + A L W + S+ + + + P+I+ E+ + Sbjct: 4 TLLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEY-E 62 Query: 57 AWKYGDNFFFLDKI----FYQGKKDAN---NGPNTYYGEFSPRLSFGKIFDQKLEFGPVK 109 A+ D F F I F+ G A N + + E PR S K+ + L FGP K Sbjct: 63 AFAKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGPFK 122 Query: 110 DVLLAMTYEFGEGDTES 126 + A Y + G +S Sbjct: 123 EWYFANNYIYDMGRNDS 139
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.0 bits (184), Expect = 5e-19 Identities = 36/206 (17%), Positives = 76/206 (36%), Gaps = 20/206 (9%) Query: 5 RERNKELILRAASEEFADKGFAATKTSDIAAKAGLPKPNVYYYFKSKENLYREVLESIIA 64 + ++ IL A F+ +G ++T +IA AG+ + +Y++FK K +L+ E+ E + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 65 PIMQAS------TPFNADGDPKEVLSAYIRSKIRISRDLPHASKVFASEIMHGAPHLSPR 118 I + P + +E+L + S + R +F G + + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 119 QVEQLNEQARHNIE-CIQRWIERGQI-AHVDPHHLMFSIWAATQTYADFDWQIAVVTGKA 176 L ++ IE ++ IE + A + + I+ + Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY----------ISGLMENW 178 Query: 177 KLADSDYDAA--AETIIRLVLKGCEP 200 A +D A + ++L+ Sbjct: 179 LFAPQSFDLKKEARDYVAILLEMYLL 204
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 118 bits (298), Expect = 2e-37 Identities = 68/158 (43%), Positives = 95/158 (60%), Gaps = 28/158 (17%) Query: 1 MANENEINSPEEQALADEWAAALEE-----TGDAGQADIDALLGGDAGHLGGDRLPMEEF 55 M++ N + AL D WA AL E T A A L GGD Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGD-------------- 46 Query: 56 ASSPKPNEHVSLEGPNLDVILDIPVSISMEVGSTEISIRNLLQLNQGSVIELDRLAGEPL 115 VS ++D+I+DIPV +++E+G T ++I+ LL+L QGSV+ LD LAGEPL Sbjct: 47 ---------VSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPL 97 Query: 116 DVLVNGTLIAHGEVVVVNEKFGIRLTDVISPSERIKKL 153 D+L+NG LIA GEVVVV +K+G+R+TD+I+PSER+++L Sbjct: 98 DILINGYLIAQGEVVVVADKYGVRITDIITPSERMRRL 135
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 255 bits (654), Expect = 9e-86 Identities = 95/324 (29%), Positives = 165/324 (50%), Gaps = 9/324 (2%) Query: 5 DLLSQDEIDALLHGVDDG---LVQTESAGEPGSIKSYDLTSQDRIVRGRMPTLEMINERF 61 ++LSQDEID LL + G + + I YD D+ + +M TL +++E F Sbjct: 3 EVLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETF 62 Query: 62 ARYTRISMFNLLRRSADVAVGGVQVMKFGEYVHSLYVPTSLNLVKIKPLRGTALFILDAK 121 AR T S+ LR V V V + + E++ S+ P++L ++ + PL+G A+ +D Sbjct: 63 ARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPS 122 Query: 122 LVFKLVDNFFGGDGRHAKIEGREFTPTELRVVRMVLDQCFVDLKEAWQAIMPVTFEYINS 181 + F ++D FGG G+ AK++ R+ T E V+ V+ + +++E+W ++ + Sbjct: 123 ITFSIIDRLFGGTGQAAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 182 EVNPAMANIVGPSEAVVVSTFHIELDGGGGDLHVTMPYSMIEPVREMLDAGF--QSDLDD 239 E NP A IV PSE VV+ T ++ G ++ +PY IEP+ L + F S Sbjct: 182 ETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRRS 241 Query: 240 QDERWVKALREDVLDVNVPVSATVARRQLKLRDILHMQPGDVIPVE---LPEHLVLRANG 296 +++ LR+ + V++ V A V +L +RDIL ++ GD+I + + + VL Sbjct: 242 STTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIGN 301 Query: 297 VPSFKARLGSHKGTLSLQIIDPIE 320 F + G ++ QI++ IE Sbjct: 302 RKKFLCQPGVVGKKIAAQILERIE 325
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 47.9 bits (113), Expect = 5e-08 Identities = 48/167 (28%), Positives = 76/167 (45%), Gaps = 9/167 (5%) Query: 282 TPKTANAVPVTPNP-LQQPLAMNQGAWAEGLVNRVMYLSSQNLKSADIQLEPAELGRLDI 340 TP +P P L PL ++ W + L + + Q +SA+++L P +LG + I Sbjct: 216 TPHQTQPLPTVAAPVLSAPLGSHE--WQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQI 273 Query: 341 RVNVAADQPTQIHFVSGHAGVRDALDSQVYRLRELFAQQGLAQPDVSVADQS-RGQQQQQ 399 + V +Q QI VS H VR AL++ + LR A+ G+ +++ +S GQQQ Sbjct: 274 SLKVDDNQ-AQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAA 332 Query: 400 AQQGGSSLSGVAARRAEAVGEGVDPVEGARPAEHQVVVGDSMVDYYA 446 +QQ S E + D + V G+S VD +A Sbjct: 333 SQQQQSQ----RTANHEPLAGEDDDTLPVPVSLQGRVTGNSGVDIFA 375
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 6e-17 Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 3/135 (2%) Query: 8 TVLVAEDGAADRLLLAQIVRRQGHVVVTAENGEQAVALFAERRPQLVLLDALMPVMDGFE 67 T+LVA+D AA R +L Q + R G+ V N A LV+ D +MP + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 68 AARRIKALAGESLVPIIFLTSLNEEEGLVRCLEAGGDDFMAKPYSA-VILAAKIRAMDRL 126 RIK + +P++ +++ N ++ E G D++ KP+ ++ RA+ Sbjct: 65 LLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 127 RRLQATVLEQRDQIA 141 +R + + + Sbjct: 123 KRRPSKLEDDSQDGM 137
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 49.0 bits (116), Expect = 3e-10 Identities = 39/134 (29%), Positives = 72/134 (53%) Query: 10 LVPVVEMAEEAERKAAQRLGHFQKLLSDAQAKQAELESFREAYQQQWINRGSQGVDGNWL 69 L + ++AE+ AA+ LG ++ A+ + L ++ Y+ + S G+ N Sbjct: 7 LATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRW 66 Query: 70 VNYQRFLGQLETAMTQQRQSMAWHQNNLNNARNTWQQAYARVEGLRKLVQRYLDEARRAE 129 +NYQ+F+ LE A+TQ RQ + ++ A N+W++ R++ + L +R A AE Sbjct: 67 INYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAALLAE 126 Query: 130 DKREQKLLDELSQR 143 ++ +QK +DE +QR Sbjct: 127 NRLDQKKMDEFAQR 140
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 58.7 bits (141), Expect = 1e-12 Identities = 50/201 (24%), Positives = 92/201 (45%), Gaps = 18/201 (8%) Query: 35 PEPEPEVIEEEVEEVPLEEVQPLTLEELEAIRQEAYNEGFATGEREGFHSTQLKVRQE-- 92 P V E EE +EE +P ++L ++ +A+ +G+ G EG + QE Sbjct: 17 PPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGL 76 Query: 93 ----------AEVALAAKLASLEQIMSHLLEPIAEQDTQIEKALVQLVAGMTRQVIGREL 142 A+ A A ++Q++S + D+ I L+Q+ RQVIG+ Sbjct: 77 AQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIGQTP 136 Query: 143 RSDSSQITHVLREALKLLPMGADNIRIHLNPQDF----ELAKALRERHEESWKLLEDESL 198 D+S + +++ L+ P+ + ++ ++P D ++ A H W+L D +L Sbjct: 137 TVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLH--GWRLRGDPTL 194 Query: 199 LPGGCRIETAHSRIDATMETR 219 PGGC++ +DA++ TR Sbjct: 195 HPGGCKVSADEGDLDASVATR 215
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 304 bits (781), Expect = e-104 Identities = 107/330 (32%), Positives = 205/330 (62%) Query: 10 KLSRVDKAAILLLSLGETDAAQVLRHMGPKEVQRVGVAMAQMGNVHREQVEQVMSEFVEI 69 L+ KAAILL+S+G +++V +++ +E++ + +A++ + E + V+ EF E+ Sbjct: 14 ALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKEL 73 Query: 70 VGDQTSLGVGSDGYIRKMLNQALGEDKANGLIDRILLGGNTSGLDSLKWMEPRAVADVIR 129 + Q + G Y R++L ++LG KA +I+ + + + ++ +P + + I+ Sbjct: 74 MMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQ 133 Query: 130 YEHPQIQAIVVAYLDPDQAGEVLSNFDHKVRLDIVLRVSSLNTVQPAALKELNQILEKQF 189 EHPQ A++++YLDP +A +LS+ +V+ ++ R++ ++ P ++E+ ++LEK+ Sbjct: 134 QEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKL 193 Query: 190 SGNSNAARTTLGGIKRAADIMNFLDSSVEGALMDAIREIDSDLSEQIEDLMFVFNNLADV 249 + S+ T+ GG+ +I+N D E +++++ E D +L+E+I+ MFVF ++ + Sbjct: 194 ASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLL 253 Query: 250 DDRGIQALLREVSSDVLVVSLKGADERVKDKIFKNMSKRASELLRDDLEAKGPVRVSDVE 309 DDR IQ +LRE+ L +LK D V++KIFKNMSKRA+ +L++D+E GP R DVE Sbjct: 254 DDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVE 313 Query: 310 TAQKEILTIARRMAEAGEIVLGGKGAEEMI 339 +Q++I+++ R++ E GEIV+ G E+++ Sbjct: 314 ESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 536 bits (1383), Expect = 0.0 Identities = 199/572 (34%), Positives = 306/572 (53%), Gaps = 35/572 (6%) Query: 28 LENISQMPMLRQVGLLVGLAASVAIGFAVVLWSQQPDYRPLYGSLAGMDTKQVVDALASA 87 LE ++++ ++ L+V +A+VAI A+VLW++ PDYR L+ +L+ D +V L Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQM 72 Query: 88 DIPYKVEPNSGALLVKADDLSRARLKLAAAGVAPSDGNVGFELLDKEQGLGTSQFMEATR 147 +IPY+ SGA+ V AD + RL+LA G+ P G VGFELLD+E+ G SQF E Sbjct: 73 NIPYRFANGSGAIEVPADKVHELRLRLAQQGL-PKGGAVGFELLDQEK-FGISQFSEQVN 130 Query: 148 YRRGLEGELARTVSSLNNVKAARVHLAIPKSSVFVRDERKPSASVLVELYPGRSLEAGQV 207 Y+R LEGELART+ +L VK+ARVHLA+PK S+FVR+++ PSASV V L PGR+L+ GQ+ Sbjct: 131 YQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQI 190 Query: 208 MAIVNLVATSVPELDKSQVTVVDQKGNLLSDQLQDTALTMAGKQFDYSRRMEGMLTQRVH 267 A+V+LV+++V L VT+VDQ G+LL+ + + Q ++ +E + +R+ Sbjct: 191 SAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSN-TSGRDLNDAQLKFANDVESRIQRRIE 249 Query: 268 NILQPVLGNDRYKAEVSTDVDFSAVESTSEQFNPDQPA----LRSEQSVNEQRASSQGPQ 323 IL P++GN A+V+ +DF+ E T E ++P+ A LRS Q ++ + P Sbjct: 250 AILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPG 309 Query: 324 GVPGALSNQPPAGASAPENAKAAATPAGAIQPGQPLVDANGQQIMDPATGQPMLAPYPSD 383 GVPGALSNQP AP P N Q +T + P Sbjct: 310 GVPGALSNQPAPPNEAPIAT-------------PPTNQQNAQNTPQTSTSTNSNSAGPRS 356 Query: 384 KRQQSTKNFELDRSISHTRQQQGRLTRLSVAVVVDDQVKLDAATGEATRTPWGAEDLARF 443 ++ T N+E+DR+I HT+ G + RLSVAVVV+ + D P A+ + + Sbjct: 357 TQRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQI 411 Query: 444 TRLVQDAVGFDASRGDSVTVINVPFAADRGDELVDIPFYSQPWFWDIVKQVLGVLFILVL 503 L ++A+GF RGD++ V+N PF+A + ++PF+ Q F D + L +LV+ Sbjct: 412 EDLTREAMGFSDKRGDTLNVVNSPFSA-VDNTGGELPFWQQQSFIDQLLAAGRWLLVLVV 470 Query: 504 VF----GVLRPVLNNITGGGKQAATDSDMELGGMIGLDGELANDRVSLGGPTSILLPSPS 559 + +RP L K A + + ++ L+ D + L Sbjct: 471 AWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRL---- 526 Query: 560 EGYEAQLNAIKGLVAEDPGRVAQVVKEWINAD 591 G E I+ + DP VA V+++W++ D Sbjct: 527 -GAEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 78.9 bits (194), Expect = 1e-22 Identities = 43/94 (45%), Positives = 55/94 (58%), Gaps = 3/94 (3%) Query: 17 MQAEAMSQPKVAAAPELAPGQSSFADMLGQAIGKVHETQQASSQLANAFEIGKSGVDLTD 76 +QA AMS + P+ SFA L A+ ++ +TQ A+ A F +G+ GV L D Sbjct: 13 LQATAMSARAQESLPQ---PTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALND 69 Query: 77 VMIASQKASVSFQALTQVRNKLVQAYQDIMQMPV 110 VM QKASVS Q QVRNKLV AYQ++M M V Sbjct: 70 VMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 552 bits (1423), Expect = 0.0 Identities = 128/415 (30%), Positives = 231/415 (55%), Gaps = 22/415 (5%) Query: 9 GVHSEAGKLRKVMVCSPGLAHKRLTPSNCDELLFDDVIWVDQAKRDHFDFVTKMRERGVD 68 + SE G+L+KV++ PG + LTP LFDD+ +++ A+++H F + ++ V+ Sbjct: 9 NIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNNLVE 68 Query: 69 VLEMHNLLTDIVQQPEALK------WILDRKITSDTVGVGLTNEVRSWLEGLDPRHLAEF 122 + + +L+++++ AL+ +IL+ +I +D N ++ + L ++ Sbjct: 69 IEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFT----INLLKDYFSSLTIDNMISK 124 Query: 123 LIGGVAGQDLPESEGASVVKMYNDYLGHSSFILPPLPNTQFTRDTTCWIYGGVTLNPMYW 182 +I GV ++L + + G + FI+ P+PN FTRD I GVT+N M+ Sbjct: 125 MISGVVTEELKNYTSSL----DDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFT 180 Query: 183 PARRQETLLTTAIYKFHKEFTNADFQVWYGDPDKDHGNATLEGGDVMPIGKGVVLIGMGE 242 R++ET+ I+K+H + + +W ++ A+LEGGD + + KG+++IG+ E Sbjct: 181 KVRQRETIFAEYIFKYHPVYK-ENVPIWLNRWEE----ASLEGGDELVLNKGLLVIGISE 235 Query: 243 RTSRQAIGQLAQNLFA-KGAVEKVIVAGLPKSRAAMHLDTVFSFCDRDLVTVFPEVVKEI 301 RT +++ +LA +LF K + + ++ +PK+R+ MHLDTVF+ D + T F Sbjct: 236 RTEAKSVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYF 295 Query: 302 VPFIIRPDESKPYGMDVRRENKSFIEVVGEHLGVKLRVVE-TGGNSFAAEREQWDDGNNV 360 +++ + S + +++E +V+ +LG K+ +++ GG+ REQW+DG NV Sbjct: 296 SIYVLTYNPSSSK-IHIKKEKARIKDVLSFYLGRKIDIIKCAGGDLIHGAREQWNDGANV 354 Query: 361 VAVEPGVVIGYDRNTYTNTLLRKAGIEVITISAGELGRGRGGGHCMTCPIVRDPI 415 +A+ PG +I Y RN TN L + GI+V I + EL RGRGG CM+ P++R+ I Sbjct: 355 LAIAPGEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 421 bits (1084), Expect = e-151 Identities = 143/310 (46%), Positives = 196/310 (63%), Gaps = 13/310 (4%) Query: 2 RIVVALGGNALLRRGEPMTADNQRANIRTATEQIAKIHP-GNELVIAHGNGPQVGLLALQ 60 R+V+ALGGNAL +RG+ + + N+R QIA+I G E+VI HGNGPQVG L L Sbjct: 4 RVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLLH 63 Query: 61 ---GLSYKADEAYPLDVLGAETEGMIGYMIEQELGNLLA---FEVPFATLLTQVEVDAND 114 G + A P+DV GA ++G IGYMI+Q L N L E T++TQ VD ND Sbjct: 64 MDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKND 123 Query: 115 PAFKDPTKFIGPVYAKDEAERLAKEKGWVVKPD-GDKYRRVVASPKPKRIFEIRPIKWLL 173 PAF++PTK +GP Y ++ A+RLA+EKGW+VK D G +RRVV SP PK E IK L+ Sbjct: 124 PAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLV 183 Query: 174 EKSSIVICAGGGGIPTMYDENRKLKGIEAVIDKDLCSALLAEQLEADLLIIATDVDAAYI 233 E+ IVI +GGGG+P + ++ ++KG+EAVIDKDL LAE++ AD+ +I TDV+ A + Sbjct: 184 ERGVIVIASGGGGVPVILEDG-EIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 234 DWGKPTQKAIAQAHPDELEKL----GFAAGSMGPKVQAACDFARNTGRVAVISSLENIED 289 +G ++ + + +EL K F AGSMGPKV AA F G A+I+ LE + Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 290 IVKGTAGTRV 299 ++G GT+V Sbjct: 303 ALEGKTGTQV 312
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 332 bits (852), Expect = e-111 Identities = 117/356 (32%), Positives = 185/356 (51%), Gaps = 35/356 (9%) Query: 177 ERLSALHHDHAEGFDAMLGDSPAIRTLKARALRVATLDAPLLVHGETGTGKELVARACHA 236 +R + D ++ ++G S A++ + R+ D L++ GE+GTGKELVARA H Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 237 ISSRHAAPFLALNCAALPESLAESELFGYAPGAFTGAQRGGKPGLMELANQGTVFLDEIG 296 R PF+A+N AA+P L ESELFG+ GAFTGAQ G E A GT+FLDEIG Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRST-GRFEQAEGGTLFLDEIG 241 Query: 297 EMSPYLQAKLLRFLSDGSFRRVGGDREVKVDVRIISATHRDLERMVAEGTFREDLFYRLN 356 +M Q +LLR L G + VGG ++ DVRI++AT++DL++ + +G FREDL+YRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 357 VLNLQVPPLRERGQDILSLAQFFMQQACTQIQRPACRLAPATHPALLANPWPGNVRQLQN 416 V+ L++PPLR+R +DI L + F+QQA + R + A+PWPGNVR+L+N Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 417 VIFRAAAICESNVVDIGDL------DIAGTSVARGQD----------------------- 447 ++ R A+ +V+ + +I + + + Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 448 ---GEVASLEQAVGDFERELLQRLYASYPSTRQLAGR-LQTSHTAIAQRLRKYGIP 499 ++ + + E L+ + + A L + + +++R+ G+ Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.011 Identities = 20/153 (13%), Positives = 41/153 (26%), Gaps = 13/153 (8%) Query: 413 VDAAQLGLSLDETSTQADVEAL-------WQLFADGQAIPDFTALANTIAVRLPAGLLRQ 465 V + L L +AD Q + L ++LP Q Sbjct: 118 VRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQ 177 Query: 466 SAILEHPVFNRYHSETELMRYLRRLADKDLALDRSMIPLGSCTMKLNAASEMIPVTWTEF 525 + E + + + + + K+L LD+ + ++N + V + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 526 GNLHPFAPAEQSQGYLQMTT--ELEAMLCAATG 556 + + + E E A Sbjct: 238 DDFSSLL----HKQAIAKHAVLEQENKYVEAVN 266
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.036 Identities = 17/85 (20%), Positives = 30/85 (35%), Gaps = 5/85 (5%) Query: 14 AIHHGYDPLSHGGALVPPVYQTATYAFPTVEYGAACFAGEEPGHFYSRISNPTLALLEQR 73 I HG L GG ++ + VE + + + N + +R Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQN-----VRER 321 Query: 74 MASLEGGEAGLALASGMGAITATLW 98 + L G EA + L+ G + A + Sbjct: 322 LQMLYGTEAQIKLSEKQGKVNAMVL 346
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 71.0 bits (174), Expect = 6e-15 Identities = 53/150 (35%), Positives = 69/150 (46%), Gaps = 17/150 (11%) Query: 33 VDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKSGTTGEEVDLALLVDGLQAEREQGITI 92 VD GK+TL LL++S I E S GTT D ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAITE-------LGSVDKGTT--------RTDNTLLERQRGITI 56 Query: 93 DVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILVDARYGVQTQTRRHSYIA 152 F K I DTPGH + + S D AI+L+ A+ GVQ QTR + Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 153 SLLGIKHIVVAVNKMDLKGFD-EQVFESIK 181 +GI I +NK+D G D V++ IK Sbjct: 117 RKMGIPTIFF-INKIDQNGIDLSTVYQDIK 145
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 64.3 bits (156), Expect = 1e-13 Identities = 36/194 (18%), Positives = 63/194 (32%), Gaps = 38/194 (19%) Query: 103 ESSLGSAVIMSPEGYLLTNNHVTSGADQIVVALK------------DGRETLARVIGSDP 150 + + S V++ LLTN HV ALK +G T ++ Sbjct: 100 GTFIASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 151 ETDLAVLKIDL--------NSLPAITIGRSDNIHIGDVTLAIGNPFGVGQTVTMGIISAT 202 E DLA++K + T+ + + G P TM + Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESK 215 Query: 203 GRNQLGLNNYEDFIQTDAAINPGNSGGALVDANGNLVGINTAIFSKSGGSQGIGFAIP-- 260 G+ L +Q D + GNSG + + ++GI+ G+ Sbjct: 216 GK-ITYLKGE--AMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 261 VKLALEVMKSIVEH 274 V + V + ++ Sbjct: 264 VFINENVRNFLKQN 277
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 28.1 bits (62), Expect = 0.047 Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 18/62 (29%) Query: 9 DMPPPVKTVGVLAWMRSNLFSSWL------------------NTLLTLFALYLVWLIVPP 50 D P P+ + + W N+ SS L L++L+A + + L+VPP Sbjct: 47 DEPAPLNAMTLAQWSSPNVLSSLLAVYSDHIYRNQPMMIRENKPLISLWAQWYIGLMVPP 106 Query: 51 LV 52 L+ Sbjct: 107 LM 108
>BACINVASINC#Salmonella/Shigella invasin protein C signature. Length = 409 Score = 28.3 bits (62), Expect = 0.047 Identities = 23/99 (23%), Positives = 43/99 (43%), Gaps = 9/99 (9%) Query: 68 AVAAAVFGDATKVKFSQLNAKERFTALQS---------GEVDVLSRNTTWTSSRDAGMGL 118 A++ ++ A ++ + + AK + LQ+ ++D L+ + + G Sbjct: 173 ALSGSISQSALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNS 232 Query: 119 VFAGVTYYDGVGFLANKKLGVSSAKELDGATICIQAGTT 157 V G D + L KK G + K L+ AT+ AGT+ Sbjct: 233 VKLGAEGVDSLKSLNMKKTGTDATKNLNDATLKSNAGTS 271
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.7 bits (82), Expect = 3e-04 Identities = 19/85 (22%), Positives = 34/85 (40%), Gaps = 3/85 (3%) Query: 16 PQAAEPVAVTPAAPAAQPPVEKAPARQHAKPRAAAKPQAEPQPAHQPRAEQPARDKPRRE 75 P A+P++VT PA P + +P+ P+P + KP+ + Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE---KPKPK 95 Query: 76 RKPKPQASLWKPEDFVVEPQEGKTR 100 KPKP+ E + + ++R Sbjct: 96 PKPKPKPVKKVQEQPKRDVKPVESR 120 Score = 31.5 bits (71), Expect = 0.006 Identities = 18/69 (26%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Query: 16 PQAAEPVAVTPAAPAAQPPVEKAPARQHAKPRAAAKPQAEPQPAHQPRAEQPARD-KPRR 74 P V P +P E + KP+ +P+P + + EQP RD KP Sbjct: 60 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQ-EQPKRDVKPVE 118 Query: 75 ERKPKPQAS 83 R P + Sbjct: 119 SRPASPFEN 127
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 383 bits (984), Expect = e-131 Identities = 135/369 (36%), Positives = 195/369 (52%), Gaps = 17/369 (4%) Query: 164 ERIEHLASRAEDEHQRAEVYRQASGQD-RELIGQSKAHKRLVEEIRLVGGSDLTVLITGE 222 + + RA E +R + QD L+G+S A + + + + +DLT++ITGE Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGE 168 Query: 223 TGVGKELVAQALHRASQRADKPMVSLNCAALPDTLVESELFGHVRGAFTGAHGERRGKFE 282 +G GKELVA+ALH +R + P V++N AA+P L+ESELFGH +GAFTGA G+FE Sbjct: 169 SGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFE 228 Query: 283 LANGGTLFLDEVGELPLAVQAKLLRVLQSGQLQRLGSDREHRVDVRLIAATNRDLAEEVR 342 A GGTLFLDE+G++P+ Q +LLRVLQ G+ +G R DVR++AATN+DL + + Sbjct: 229 QAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSIN 288 Query: 343 SGHFRADFYHRLSVYPLHVPPLRERGRDVLLLAGYFLEQNHSRLGLGSLRLSADAQAALL 402 G FR D Y+RL+V PL +PPLR+R D+ L +F++Q + GL R +A + Sbjct: 289 QGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMK 347 Query: 403 AYGWPGNVRELEHLIGRSALKALGQHGQRPKIL---------------TLEAADLDLRNL 447 A+ WPGNVRELE+L+ R R I + L + Sbjct: 348 AHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQA 407 Query: 448 APAMPVVAEAPSADVPLPEGGLREAVDDYQRQVVEACLNRHHDNWAAAARELGLDRANLS 507 A D P G + + + ++ A L N AA LGL+R L Sbjct: 408 VEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLR 467 Query: 508 RLAKRLGLR 516 + + LG+ Sbjct: 468 KKIRELGVS 476
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 9e-11 Identities = 23/109 (21%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 169 AANILVVDDSQVALQQSVHTLRNLGIECHTARSAKDAINVLLELQGTDREINIIVSDIEM 228 A ILV DD L G + +A + G +++V+D+ M Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-----DLVVTDVVM 57 Query: 229 SEMDGFAFTRTLRETPDFQHLYILLHTSLDSAMSGDKAKLAGANAILTK 277 + + F +++ L +L+ ++ ++ M+ KA GA L K Sbjct: 58 PDENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 60.2 bits (146), Expect = 5e-12 Identities = 31/196 (15%), Positives = 69/196 (35%), Gaps = 43/196 (21%) Query: 1 MRRPSRSLVLAALALVLLAAVG-TWLGVRQEAPANRTASAIPVRVVAVAQQDVPRYLSAI 59 SR L A ++ + + V +VA A + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFIL------------SVLGQVEIVATANGKL------- 90 Query: 60 GSVLSLHSVEVRPQVEGVLTQVLVKEGQWVSQGDLLATLDDRAIRANLDQARAQLGQTQA 119 S S E++P ++ +++VKEG+ V +GD+L L A+ + ++ L Q + Sbjct: 91 --THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL 148 Query: 120 QL----------------QVGNVNLKRYQLLSTDDGVSKQTLDQQQ-----ALVNQLQAT 158 + ++ + +Q +S ++ + +L ++Q Q + Sbjct: 149 EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELN 208 Query: 159 LKGNQAAIDNAAVQLS 174 L +A +++ Sbjct: 209 LDKKRAERLTVLARIN 224 Score = 33.3 bits (76), Expect = 0.002 Identities = 10/84 (11%), Positives = 31/84 (36%) Query: 96 ATLDDRAIRANLDQARAQLGQTQAQLQVGNVNLKRYQLLSTDDGVSKQTLDQQQALVNQL 155 L+ RA A++ + + +V L + L ++K + +Q+ + Sbjct: 205 KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 156 QATLKGNQAAIDNAAVQLSYTQIR 179 L+ ++ ++ ++ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEE 288 Score = 30.6 bits (69), Expect = 0.011 Identities = 24/159 (15%), Positives = 52/159 (32%), Gaps = 30/159 (18%) Query: 104 RANLDQARAQLGQTQAQLQVGNVNLKRYQLLSTDDGVSKQTLDQQQALVNQLQATLKGNQ 163 L ++QL Q ++++ + + + LD+ + Q + Sbjct: 265 VNELRVYKSQLEQIESEIL-----SAKEEYQLVTQLFKNEILDK----LRQTTDNIGLLT 315 Query: 164 AAIDNAAVQLSYTQIRSPVTGRVGIRNV-DPGNLVRTSDT-------------QSLFSVT 209 + + + IR+PV+ +V V G +V T++T +L Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNK 375 Query: 210 QID------PIAVEF-ALPQQQLPVLQSLLKSPTPAEVE 241 I ++ A P + L +K+ +E Sbjct: 376 DIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIE 414
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 761 bits (1967), Expect = 0.0 Identities = 284/1034 (27%), Positives = 493/1034 (47%), Gaps = 36/1034 (3%) Query: 12 IDHPIATLLLTFALVLLGAIAFPRLPVAPLPEADFPTIQVTAQLPGASPETMASSVATPL 71 I PI +L L++ GA+A +LPVA P P + V+A PGA +T+ +V + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVI 65 Query: 72 EVQFSAIPGMTQMTSSSA-LGSTNLILQFTLDKNIDTAAQEVQAAINTATARLPQDMPSP 130 E + I + M+S+S GS + L F + D A +VQ + AT LPQ++ Sbjct: 66 EQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQ 125 Query: 131 PTWRKVNPADSPVLILTVSST--QMPGNQLSDYAETLLARQLSQIDGVGMINITGQLRPA 188 + S +++ S + +SDY + + LS+++GVG + + G A Sbjct: 126 GI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY-A 183 Query: 189 IRVQAQPEKLAAIGLTLADIRLAIQQTSLNLAKGALYGEHSVS------TLAANDQLFHP 242 +R+ + L LT D+ ++ + +A G L G ++ ++ A + +P Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 243 EDYARLIV-SYRNGAPVHLADVAKVIDGAENAYVKAWSGDRPGLNLVIFRQPGANIVDTV 301 E++ ++ + +G+ V L DVA+V G EN V A +P L I GAN +DT Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 302 DRVLDALPRLQEMLPAAVDVSVLQDRTQTIRASLHEVELTLMVAVALVIGVMALFLRQWS 361 + L LQ P + V D T ++ S+HEV TL A+ LV VM LFL+ Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 362 ATFIVSSVLGVSLIASCALMYVFGFSLNNLTLVAIVIAVGFVVDDAIVVVENIHRHL-EA 420 AT I + + V L+ + A++ FG+S+N LT+ +V+A+G +VDDAIVVVEN+ R + E Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 421 GDDSRTAALKGAGEIGFTVVSISFSLIAAFIPLLFMGGVVGRLFKEFALTATATILISVV 480 + A K +I +V I+ L A FIP+ F GG G ++++F++T + + +SV+ Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 481 VSLTLAPTLAALCMRRPPEEQHGGLGQRLVRWYEKGLDRA-----------LAHRRVTLG 529 V+L L P L A + +P +H W+ D + L L Sbjct: 484 VALILTPALCAT-LLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLL 542 Query: 530 VFGLTLALAVAGYVAIPKGFFPLQDTGFILGTTEAAADVSYPAMIEKHQALAKIIEADPA 589 ++ L +A V ++ +P F P +D G L + A + + + + Sbjct: 543 IYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEK 602 Query: 590 --VRAFSHSVGVTGSNQTIANGRFWISLKPRGERDV---SASEWIDRMRPRLMQIPGIVL 644 V + G + S Q G ++SLKP ER+ SA I R + L +I + Sbjct: 603 ANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFV 662 Query: 645 YLRAGQDINLSSGPSRTQYQYVLKSNDGV-ALNLWTQRLTERLRENPA-FRDLSNDLQLG 702 I + ++ + ++ G AL +L ++PA + + Sbjct: 663 IPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 703 ASVTRIDIDRQAAARFGLTTTDVDQALYDAFGQRQISEFQTETNQYKVILELDARQRGKA 762 + ++++D++ A G++ +D++Q + A G +++F K+ ++ DA+ R Sbjct: 723 TAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLP 782 Query: 763 ESLNYFYLRSPLSGEMVPLSALAHVAPPSTGPLSISHDGLFPAANLSFNLAPGVALGEAV 822 E ++ Y+RS +GEMVP SA G + P+ + APG + G+A+ Sbjct: 783 EDVDKLYVRSA-NGEMVPFSAFTTSHW-VYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 823 QILERTQRELGMPDAIAGNFQGAAQAFQSSLSSQPYLILAALVAVYIILGVLYESFVHPL 882 ++E +L P I ++ G + + S + P L+ + V V++ L LYES+ P+ Sbjct: 841 ALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 883 TIISTLPSAGLGALILLWLMGQDFTIMGLIGVVLLIGIVKKNGILLIDFALDAQRHQGMT 942 +++ +P +G L+ L Q + ++G++ IG+ KN IL+++FA D +G Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 943 PEQAIRQACLVRFRPIIMTTLAALLGAVPLMFGFGTGAELRQPLGIAVVGGLLVSQALTL 1002 +A A +R RPI+MT+LA +LG +PL G G+ + +GI V+GG++ + L + Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1003 FTTPVIYLALERLF 1016 F PV ++ + R F Sbjct: 1019 FFVPVFFVVIRRCF 1032 Score = 97.2 bits (242), Expect = 2e-22 Identities = 80/515 (15%), Positives = 169/515 (32%), Gaps = 41/515 (7%) Query: 9 AWCIDHPIATLLLTFALVLLGAIAFPRLPVAPLPEADFPTIQVTAQLP-GASPETMASSV 67 + LL+ +V + F RLP + LPE D QLP GA+ E + Sbjct: 531 GKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVL 590 Query: 68 ATPLEVQF-SAIPGMTQMTSSSALG----STNLILQFTLDKNID--TAAQEVQAAINTAT 120 + + + + + + + N + F K + + A+ Sbjct: 591 DQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAV---I 647 Query: 121 ARLPQDMPSPPTWRKVNPADSPVLILTVSS---------TQMPGNQLSDYAETLLARQLS 171 R ++ + ++ L ++ + + L+ LL Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQ 707 Query: 172 QIDGVGMINITGQ-LRPAIRVQAQPEKLAAIGLTLADIRLAIQQTSLNLAKGALYG---- 226 + + G +++ EK A+G++L+DI +++ A G Y Sbjct: 708 HPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDI-----NQTISTALGGTYVNDFI 762 Query: 227 ----EHSVSTLAANDQLFHPEDYARLIVSYRNGAPVHLADVAKVIDGAENAYVKAWSGDR 282 + A PED +L V NG V + + ++ ++G Sbjct: 763 DRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG-L 821 Query: 283 PGLNLVIFRQPGANIVDTVDRVLDALPRLQEMLPAAVDVSVLQDRTQTIRASLHEVELTL 342 P + + PG + D + + L LPA + + R S ++ + Sbjct: 822 PSMEIQGEAAPGTSSGD----AMALMENLASKLPAGIGYDW-TGMSYQERLSGNQAPALV 876 Query: 343 MVAVALVIGVMALFLRQWSATFIVSSVLGVSLIASCALMYVFGFSLNNLTLVAIVIAVGF 402 ++ +V +A WS V V+ + ++ +F + +V ++ +G Sbjct: 877 AISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGL 936 Query: 403 VVDDAIVVVENI-HRHLEAGDDSRTAALKGAGEIGFTVVSISFSLIAAFIPLLFMGGVVG 461 +AI++VE + G A L ++ S + I +PL G Sbjct: 937 SAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGS 996 Query: 462 RLFKEFALTATATILISVVVSLTLAPTLAALCMRR 496 + ++ + ++++ P + R Sbjct: 997 GAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.0 bits (200), Expect = 6e-20 Identities = 30/126 (23%), Positives = 59/126 (46%), Gaps = 2/126 (1%) Query: 2 RVLIIEDEEKTADYLHRGLTEQGFTVDLARDGIDGLHLALEGDYAVIVLDVMLPGLDGYG 61 +L+ +D+ L++ L+ G+ V + + GD ++V DV++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRALRAR-KQTPVIMLTARERVEDRIHGLREGADDYLGKPFSFLELVARL-QALTRRSA 119 +L ++ PV++++A+ I +GA DYL KPF EL+ + +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 120 IHEPLQ 125 L+ Sbjct: 125 RPSKLE 130
>cloacin#Cloacin signature. Length = 551 Score = 44.7 bits (105), Expect = 7e-07 Identities = 27/83 (32%), Positives = 32/83 (38%), Gaps = 2/83 (2%) Query: 28 GGGHHSEVDGSSAD--GGTGAGTGAGAGDSGGGAGGGGTGTGGGSTPGDGSAGTGGGGGG 85 G GH++ +S + GG G G G GGGS G G G G G Sbjct: 6 GRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNG 65 Query: 86 GGGTTPGGGDGGTGGGTTPTALV 108 GG GGG G G + A V Sbjct: 66 GGNGNSGGGSGTGGNLSAVAAPV 88 Score = 38.2 bits (88), Expect = 7e-05 Identities = 29/73 (39%), Positives = 35/73 (47%), Gaps = 12/73 (16%) Query: 42 GGTGAGTGAGAGDSGGGAGGGGTG---TGGGS---------TPGDGSAGTGGGGGGGGGT 89 GG G G GA + G GG TG GG S P G +G+G GGG G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 90 TPGGGDGGTGGGT 102 GGG+G +GGG+ Sbjct: 63 GNGGGNGNSGGGS 75 Score = 31.2 bits (70), Expect = 0.010 Identities = 21/63 (33%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 21 LTGCSSGGGGHHSEVDGSSADGGTGAGTGAGAGDSGGGAGGGGTGTGGGSTPGDGSAGTG 80 + G +G G DGS G G+G GG G G GGG+ G +GTG Sbjct: 20 INGGPTGLGVGGGASDGSGW-SSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78 Query: 81 GGG 83 G Sbjct: 79 GNL 81 Score = 31.2 bits (70), Expect = 0.011 Identities = 29/93 (31%), Positives = 41/93 (44%), Gaps = 9/93 (9%) Query: 23 GCSSGGGGHHSEVDGSSADGGTGAGTGAGAGDS------GGGAGGG---GTGTGGGSTPG 73 G ++G ++G G G G G+G S GGG+G G G G+G G+ G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGG 67 Query: 74 DGSAGTGGGGGGGGGTTPGGGDGGTGGGTTPTA 106 +G++G G G GG G +TP A Sbjct: 68 NGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGA 100 Score = 31.2 bits (70), Expect = 0.011 Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 1/76 (1%) Query: 19 LGLTGCSSGGGGHHSEVDGSSADGGTGAGTGAGAGDSGGGAGGGGTGTGGGSTPGDGSAG 78 LG+ G +S G G SE + G+G G G+G GG G G +G G G+ + Sbjct: 27 LGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGG-GNGNSGGGSGTGGNLSAVA 85 Query: 79 TGGGGGGGGGTTPGGG 94 G +TPG G Sbjct: 86 APVAFGFPALSTPGAG 101 Score = 30.5 bits (68), Expect = 0.017 Identities = 24/67 (35%), Positives = 30/67 (44%), Gaps = 3/67 (4%) Query: 28 GGGHHSEVDGSSADGGTGAGTGAGAGDSGGGAGGGGTGTGGGSTPGDGSAGTGGGGGGGG 87 GGG S G GG+G G G G G+SGGG+G GG + + G G GG Sbjct: 47 GGGSGS---GIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGL 103 Query: 88 GTTPGGG 94 + G Sbjct: 104 AVSISAG 110
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.015 Identities = 10/66 (15%), Positives = 27/66 (40%) Query: 168 FGCFLIMIIILAVLALIVVKALAESPWGMFTVMATIPIAMFMGIYMRYIRPGRIGEISVI 227 ++ I V+ + + AL ES +VM +P+ + + + + ++ Sbjct: 869 GNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMV 928 Query: 228 GVILLL 233 G++ + Sbjct: 929 GLLTTI 934
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.046 Identities = 15/83 (18%), Positives = 28/83 (33%), Gaps = 3/83 (3%) Query: 117 VAQAALADERYRGRGQELM---VRLFGAYSEALFANEQIALAQAQRRTYAEQLTLNERLL 173 + +L E++ + + L +E L +I + R +L LL Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 174 KGGEGTRTDVLETRARYELAQAQ 196 + VLE +Y A + Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNE 267
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 398 bits (1025), Expect = e-138 Identities = 83/435 (19%), Positives = 167/435 (38%), Gaps = 11/435 (2%) Query: 16 LSLDEHRPGRVGR---WLVLAGFGGFLLWAALAPLDKGVPVSGSVMVAGSRQAVQHPTGG 72 L L E R R + ++ + + L ++ +G + +G + ++ Sbjct: 46 LELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENS 105 Query: 73 VIEQLLVHDGDTVSAGQVVLRMDRTQAQAQVGSLRVQYVNARAAEARLLA-----ERDGR 127 ++++++V +G++V G V+L++ A+A + + AR + R E + Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL 165 Query: 128 ASIDFPQGLRDQAASAWVATVMESQRQLRSSRAQALEMELGGLRESIAGAEASLQGLQGS 187 + P Q S L + + + ++ A + Sbjct: 166 PELKLPDEPYFQNVSEEEV---LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 188 LASKQAQRDALDEQLRGLRELARDGYIARNRLLDSERLLAQVNGSIAEDFGSIGRTRRQV 247 + + +L L IA++ +L+ E + + + + ++ Sbjct: 223 INRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282 Query: 248 LELKLRIGQRQQEYQNEVRQQLAELQASAEDLDNRLRSAEFELAHTQVRAPVAGTVVGLS 307 L K Q ++NE+ +L + + L L E + +RAPV+ V L Sbjct: 283 LSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLK 342 Query: 308 VFTDGGVIARGQQLMEIVPRDAPLLVEARASVDMIDRLRPGLPVELMFVAFNQSTTPRVD 367 V T+GGV+ + LM IVP D L V A I + G + AF + + Sbjct: 343 VHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLV 402 Query: 368 GEVTLVSADRLIDEKTQQPYYQVRIKVSDQGLGQLAGLDIRPGMPVEAFVRTGERSLLNY 427 G+V ++ D + D++ + + + + + GM V A ++TG RS+++Y Sbjct: 403 GKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISY 462 Query: 428 LFKPLADRVHVALAE 442 L PL + V +L E Sbjct: 463 LLSPLEESVTESLRE 477
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 178 bits (453), Expect = 4e-59 Identities = 97/217 (44%), Positives = 124/217 (57%), Gaps = 24/217 (11%) Query: 1 MTLSVNYDAAFASSTVDDYLAFWSAGFVTAGH------GYSNTGGFSNGTFDGDQYATHG 54 M++S++Y ++ TV DYLA WSA F H SNTGGF+ G FDG QYA Sbjct: 1 MSISISYSTTYSGWTVADYLADWSAYFGDVNHRPGQVVDGSNTGGFNPGPFDGSQYALKS 60 Query: 55 RNNSDYAFIADSDSANGLHYVFDPSKAPGDNLNHYLWGSLDNVSLGEVLGGGSGS-DFSL 113 SD AFIA D LHY N +H LWG LD+++LG+ L GG+ S ++L Sbjct: 61 -TASDAAFIAGGD----LHYTL------FSNPSHTLWGKLDSIALGDTLTGGASSGGYAL 109 Query: 114 GNYVVSFNGLDLDAAQGAGRAGNEVQGVIYGLMQGNTSALEGVLDNLLAG--YGVSTNNT 171 + VSF+ L LD+ GR G V V+YGLM G++SAL+G +D LL +S N+T Sbjct: 110 DSQEVSFSNLGLDSPIAQGRDGT-VHKVVYGLMSGDSSALQGQIDALLKAVDPSLSINST 168 Query: 172 FAEIGAALAAGPAHAAAA---EAVGVQALPEDLALAA 205 F ++ AA A AAAA VGVQ LP DLALAA Sbjct: 169 FDQLAAAGVAHATPAAAAAEVGVVGVQELPHDLALAA 205
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 1e-05 Identities = 25/136 (18%), Positives = 52/136 (38%), Gaps = 14/136 (10%) Query: 410 GKTLRVAAALALLLAVL-----VVPWRGAVDVPAMLEASRVNALHAPVAARVKRLPVQEG 464 + +A +L+VL V G + + R + + VK + V+EG Sbjct: 61 AYFIMGFLVIAFILSVLGQVEIVATANGKLTH-----SGRSKEIKPIENSIVKEIIVKEG 115 Query: 465 QVVAQGELLVELESPDLASRQSIVRREIDILQLLLRRQAGRSETAGDTGVLEQQLAEAVA 524 + V +G++L++L L + ++ + +LQ L + R + + L + + Sbjct: 116 ESVRKGDVLLKLT--ALGAEADTLKTQSSLLQARL--EQTRYQILSRSIELNKLPELKLP 171 Query: 525 EYRGLAAQRERLQLRA 540 + E LR Sbjct: 172 DEPYFQNVSEEEVLRL 187 Score = 37.9 bits (88), Expect = 1e-04 Identities = 20/109 (18%), Positives = 40/109 (36%), Gaps = 5/109 (4%) Query: 461 VQEGQVVAQGELLVELESPDLASRQSIVRREIDILQ----LLLRRQAGRSETAGDTGVLE 516 + + V+ Q VE + + + + E +IL L Q ++E Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTT 308 Query: 517 QQLAEAVAEYRGLAAQRERLQLRAPRAGVLRDLPADLAPGQWVSPAQTL 565 + E +++ +RAP + ++ L G V+ A+TL Sbjct: 309 DNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKV-HTEGGVVTTAETL 356
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 59.1 bits (143), Expect = 1e-11 Identities = 34/209 (16%), Positives = 66/209 (31%), Gaps = 20/209 (9%) Query: 118 WLPLLDRKGDVFGGLWLARDQAFTPAEQALLNQLGDTYAHAWLALHPVRPWRLRWPRRRL 177 + L R V+ W R Q TP + N+ AH L PV R PR Sbjct: 8 FSEFLLRYKLVWSETWKIRKQLDTPVREKDENEF--LPAHLELIETPVS----RRPRLVA 61 Query: 178 LTVAAALLLVLLV----PVRQSVLAPAEVVPRAGR-VVAAPLDGVIAEFLVKPNQTVAVG 232 + L++ ++ V A ++ + + ++ E +VK ++V G Sbjct: 62 YFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKG 121 Query: 233 DVLVRFDATTLKAQADVAGRALGVAEAEL---------KASTQRAFSDAESNARLDLLAA 283 DVL++ A +A +L A E + ++ Sbjct: 122 DVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSE 181 Query: 284 RVEQKRAELDYARQLLGRSEIRAERAGIA 312 + L + +++ + + Sbjct: 182 EEVLRLTSLIKEQFSTWQNQKYQKELNLD 210 Score = 41.0 bits (96), Expect = 8e-06 Identities = 27/137 (19%), Positives = 49/137 (35%), Gaps = 6/137 (4%) Query: 239 DATTLKAQADVAGRALGVAEAELKASTQRAFSDAESNARLDLLAARVEQKRAELDYARQL 298 + K+Q + + A+ E + TQ ++ +L + EL + Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD--KLRQTTDNIGLLTLELAKNEER 324 Query: 299 LGRSEIRAERAGIAVFADAERWTGKPVQTGERLMQLADPQQAELRLE--LPVGDAIALQP 356 S IRA + V G V T E LM + P+ L + + D + Sbjct: 325 QQASVIRAPVSVK-VQQLKVHTEGGVVTTAETLMVIV-PEDDTLEVTALVQNKDIGFINV 382 Query: 357 GAEVALFLDSDPLHRHG 373 G + +++ P R+G Sbjct: 383 GQNAIIKVEAFPYTRYG 399
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.7 bits (129), Expect = 2e-10 Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 8/154 (5%) Query: 77 DCSAYQAQLNAAQAAVRAASEELRHNRQLAALKSVGQFEVSLAEAKQAQAQAEAQVYQVQ 136 + Y++QL ++ + +A EE + QL K+ ++ E + + Sbjct: 267 ELRVYKSQLEQIESEILSAKEEYQLVTQL--FKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 137 IKRCVISAPFDGRVVQRRAQPHESV-PSGAPLIEVV-DNRSLEIHLLVPSRWLGRLKPGQ 194 + VI AP +V Q + V + L+ +V ++ +LE+ LV ++ +G + GQ Sbjct: 325 QQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQ 384 Query: 195 P----FEFVPDETGRPLQAQVKRVGARIDEGSQT 224 E P L +VK + E + Sbjct: 385 NAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Score = 32.5 bits (74), Expect = 0.001 Identities = 15/80 (18%), Positives = 34/80 (42%), Gaps = 1/80 (1%) Query: 54 GRIVEMPFADGQDFKKGSTLARFDCSAYQAQLNAAQAAVRAAS-EELRHNRQLAALKSVG 112 + E+ +G+ +KG L + +A Q+++ A E+ R+ +++ Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 113 QFEVSLAEAKQAQAQAEAQV 132 E+ L + Q +E +V Sbjct: 165 LPELKLPDEPYFQNVSEEEV 184
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 48.4 bits (115), Expect = 5e-09 Identities = 21/92 (22%), Positives = 37/92 (40%), Gaps = 4/92 (4%) Query: 38 LSHANAS---LLVAQRDGQLMGYALLLFHRGTSLARLYSIAIAEQARGHGLGARLLEQAE 94 +S+ + + +G + + A + IA+A+ R G+G LL +A Sbjct: 57 VSYVEEEGKAAFLYYLENNCIGR-IKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAI 115 Query: 95 RCALEHDRAYLRLEVRTDNPKAIALYERHGYR 126 A E+ L LE + N A Y +H + Sbjct: 116 EWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.033 Identities = 12/57 (21%), Positives = 19/57 (33%), Gaps = 6/57 (10%) Query: 88 IGTVMTAPAARGRGYSRYLMEVLVERWAGKCDLLYLF-----ANSTVLDLYPRFGFR 139 I + A R +G L+ +E WA + L N + Y + F Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIE-WAKENHFCGLMLETQDINISACHFYAKHHFI 147
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 2e-24 Identities = 36/131 (27%), Positives = 58/131 (44%), Gaps = 2/131 (1%) Query: 3 PKLLLAEDDPRLRQDLEQHFLRRGFSVLACENGTQALNTMQQAPFDLLLLDIMLPGIDGL 62 +L+A+DD +R L Q R G+ V N + DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 SLLDELRRHQA-VPVMLMSALGAEQDRISGFTRGADDYLPKPFSLAE-LDARVDALLRRV 120 LL +++ + +PV++MSA I +GA DYLPKPF L E + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ALDRRPPAPRH 131 + Sbjct: 124 RRPSKLEDDSQ 134
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 18/99 (18%), Positives = 36/99 (36%), Gaps = 17/99 (17%) Query: 346 ENLLRNAIRHSPATGRVSLDGWREGAFWHLCLRDQGPGVPEDELEQIFQPYRRLPGSGAG 405 EN +++ I P G++ L G ++ L + + G ++ E Sbjct: 265 ENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------------S 310 Query: 406 FGLGLAIARRAIDLQGG---RLWASNGHPGLCLHLLLPA 441 G GL R + + G ++ S + +L+P Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 31.1 bits (70), Expect = 0.008 Identities = 17/70 (24%), Positives = 29/70 (41%) Query: 288 IILPGEMKTLLAQVVEAEKAAQANVIRRREETQATRSLLNTAKVMEGNPTALRLKELETL 347 I+ ++ L + VE KAAQ R+E +A L+ + ++ RL Sbjct: 473 ILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMS 532 Query: 348 ERVAERIDRI 357 +R+ E D Sbjct: 533 QRIREMSDND 542
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 216 bits (552), Expect = 2e-66 Identities = 93/325 (28%), Positives = 149/325 (45%), Gaps = 10/325 (3%) Query: 176 RREQVEGQSLLKSGIATRNQDFNRTIEQIERVALRSKAPMLLVGPTGAGKSFLARRVHEL 235 R ++E S + R+ + R+ ++ +++ G +G GK +AR +H+ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLM-QTDLTLMITGESGTGKELVARALHDY 183 Query: 236 KRGRHQLGGRFIEVNCATLRGDGAMSTLFGHAKGAFTGAQHARDGLLRAADGGMLFLDEI 295 + R G F+ +N A + D S LFGH KGAFTGAQ G A+GG LFLDEI Sbjct: 184 GKRR---NGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 296 GELGADEQAMLLKAIEEKRFFPLGADREVESDFQLIAGTHRDLRAKVADGSFREDLFARI 355 G++ D Q LL+ +++ + +G + SD +++A T++DL+ + G FREDL+ R+ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 356 NLWTFALPGLAERREDIEPNLDFELQRHAREQGRQVRFNLEAKRRYLAFAHAGEARWAGN 415 N+ LP L +R EDI + +Q+ +E RF+ EA A W GN Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAH------PWPGN 354 Query: 416 FRELSASITRMATLADIGRIDEEMVEEEIARLRYAWGLESASEPLLADRALDLFDQVQLQ 475 REL + R+ L I E++E E+ +E A+ + ++ Q Sbjct: 355 VRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQ 414 Query: 476 AVIDVCRRAPSLSEAGRQLFAVSRQ 500 P R L + Sbjct: 415 YFASFGDALPPSGLYDRVLAEMEYP 439
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.015 Identities = 16/84 (19%), Positives = 26/84 (30%), Gaps = 20/84 (23%) Query: 40 LTLLGPSGSGKTTSLMMLAGFETPTAGEIQLAGRSINNVPPHKRDIGMVFQNYALFPHMT 99 + L G G GK+T + L G + + + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDI---------GTGKDSYEQIAGIVA---YE 646 Query: 100 VAENLAFPLSVRNLSKTDISERVK 123 ++E AF + D E VK Sbjct: 647 LSEMTAF-------RRADA-EAVK 662
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 3e-14 Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 2/116 (1%) Query: 2 IRVLVAEDHTIVREGIKQLIGLAKDMQVAGEAGNGEQLLETLRHTPCEVVLLDISMPGVN 61 +LVA+D +R + Q + A N L + ++V+ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEAIPRILALNNPPAILMLSMHDEAQMAARALKAGAAGYATKDSDPALLLTAIRR 117 + +PRI +L++S + A +A + GA Y K D L+ I R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 45.6 bits (108), Expect = 4e-07 Identities = 29/137 (21%), Positives = 57/137 (41%), Gaps = 26/137 (18%) Query: 670 IASAIEWQARRFEARTQIPCLVEVPEQL-----PPLSDAKAIGLFRILQEALTNVMRHAR 724 + S ++ + +FE R Q ++ + PP+ ++Q + N ++H Sbjct: 225 VDSYLQLASIQFEDRLQFE--NQINPAIMDVQVPPM----------LVQTLVENGIKHGI 272 Query: 725 AH-----TVQIALVEEGGQLRMTVIDDGVGFAVDAARPTSFGLVGVRERVLMLGGD---M 776 A + + ++ G + + V + G + T GL VRER+ ML G + Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQI 332 Query: 777 TLESEPGEGTSLSVAIP 793 L + G+ ++ V IP Sbjct: 333 KLSEKQGKVNAM-VLIP 348
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.3 bits (73), Expect = 0.003 Identities = 30/213 (14%), Positives = 67/213 (31%), Gaps = 26/213 (12%) Query: 120 STLSVSLPDLLAERPQARVEAKPVIAPKKEEGESAPAKDTPADANANVAQATAPEADAAD 179 +T + D+ + A+ AP + P++ T A + ++ E + D Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 180 STDAVEADEHTSEEDAQRIFARLDAAVAYAQQQKARSIVLLGNGSGAYWAARYLSEKQPP 239 +T+ + ++E + A + + E Q Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETK-------------------ETQTT 1098 Query: 240 QVQKLVMVAAQTPARVEHDLLGVTSTLKVPTADLYYTTRTQDRQAAQQRLQASKREKNSQ 299 + ++ V + A+VE + T +VP + + Q+ + QA +N Sbjct: 1099 ETKETATVEKEEKAKVETE-----KTQEVPK--VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 300 YRQLSLMVVPGNKAAEQEQLLRRVRGWLKPKEE 332 + N A+ EQ + ++ Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.6 bits (77), Expect = 0.002 Identities = 19/61 (31%), Positives = 29/61 (47%) Query: 43 SMEIPAPKAGVVKELKVKLGDRLKEGDELLVLEVEGAAAAPEAPAAAPAQAAAPAPAAEA 102 S EI + +VKE+ VK G+ +++GD LL L GA A ++ QA + Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 103 A 103 Sbjct: 156 L 156
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 32.7 bits (74), Expect = 0.008 Identities = 14/55 (25%), Positives = 25/55 (45%) Query: 313 QSDEIAFAGELADQFAQVINNHNRRTAASALHLFQRAVEQSASAFLLVNRDGVVE 367 SD++ + + Q + N A++ L + SA+ F L N+DG V+ Sbjct: 494 LSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAATFTLANKDGKVD 548
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 29.4 bits (66), Expect = 0.008 Identities = 16/92 (17%), Positives = 25/92 (27%), Gaps = 7/92 (7%) Query: 94 RLTLASQADAIMDAAVATRYETF--LRPADKQWDGWVQAQG--EKIRRSLASLEREHLPE 149 SQ A ++ E F L G + + ++L S+ E Sbjct: 114 PNISLSQLKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGET 173 Query: 150 IASGFDIAAIGAACALGYLDLRQPEFDWRGLY 181 I G I A + + R Y Sbjct: 174 IVLGARITP--EAYRESQSGVNPLQ-PLRDTY 202
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 3e-04 Identities = 35/186 (18%), Positives = 70/186 (37%), Gaps = 31/186 (16%) Query: 297 IERESERLQQMIERLLNLARVEQMQALEDEQQVAVAV-----LIDELLLAHGARIDTAGL 351 I + + ++M+ L L R +L V++ ++D L + + L Sbjct: 186 ILEDPTKAREMLTSLSELMR----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDR-L 240 Query: 352 QVRQRIPAGVRLLCDPFLMRQALA-NLLDNALDFTPERGALAFELERDGERVALSLFNQG 410 Q +I + + P ++ Q L N + + + P+ G + + +D V L + N G Sbjct: 241 QFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300 Query: 411 QPIPEYALGRVSERFYSLPRPGTGRKSTGLGLNFVAEVMQLHGG---GLAVDNVEGGVRV 467 + ++STG GL V E +Q+ G + + +G V Sbjct: 301 SLALK-----------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA 343 Query: 468 RLWLPA 473 + +P Sbjct: 344 MVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 4e-17 Identities = 36/144 (25%), Positives = 67/144 (46%), Gaps = 5/144 (3%) Query: 2 PHILIVEDESAIADTLVYALQADGHSTEWVTLGSAAVEQQRQRPADLVILDIGLPDINGF 61 IL+ +D++AI L AL G+ + + DLV+ D+ +PD N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 ETCRQLR-RFSEVPVMFLSARDAEIDRVLGLEIGADDYVVKPFSPREVAARVRAIL---- 116 + +++ ++PV+ +SA++ + + E GA DY+ KPF E+ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 117 KRMAPRSDAASESTPFQLDTLAMR 140 +R + D + + P + AM+ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQ 147
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 29.0 bits (65), Expect = 0.030 Identities = 8/21 (38%), Positives = 11/21 (52%) Query: 339 EVVMIPGRELLLGGGNIHCLT 359 +V IP EL G G C++ Sbjct: 381 KVHRIPSSELSRGRGGPRCMS 401
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 176 bits (447), Expect = 2e-54 Identities = 86/356 (24%), Positives = 150/356 (42%), Gaps = 44/356 (12%) Query: 1 MRILVTGGAGFIGSALVRHLIDHTDHEVLNLDKLT--YAGNL-QSLLRVAGNSRYEFVQG 57 M+ LVTG AGFIG + + L++ H+V+ +D L Y +L Q+ L + ++F + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIADQAGVSAVLARFQPDAIMHLAAESHVDRSIDGPADFIQTNIVGTYSLLEATRGYWST 117 D+AD+ G++ + A + + V S++ P + +N+ G ++LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCR----- 114 Query: 118 LNEPARGAFRFHHV---STDEVFGDLQDTGDLFNENSSYA-PSSPYSASKAAADHLVRAW 173 + H+ S+ V+G + F+ + S P S Y+A+K A + + + Sbjct: 115 -------HNKIQHLLYASSSSVYGL--NRKMPFSTDDSVDHPVSLYAATKKANELMAHTY 165 Query: 174 HRTYGLPTVISNCSNNYGPYHFPEKLIPLTILNALAGKPLAVYGNGQQVRDWLYVEDHVR 233 YGLP YGP+ P+ + L GK + VY G+ RD+ Y++D Sbjct: 166 SHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAE 225 Query: 234 A---LLQVVTAGEVGRTYAIGGHNEQS------NIG-----VVQALCCLLEELAPVHPLG 279 A L V+ + T G NIG + LE+ Sbjct: 226 AIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA------- 278 Query: 280 VTRYADLITHVQDRPGHDLRYAIDASRIERELGWSPQETFASGLRKTVQWYLDNLE 335 + A + +PG L + D + +G++P+ T G++ V WY D + Sbjct: 279 LGIEAK-KNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 41.7 bits (98), Expect = 2e-06 Identities = 41/200 (20%), Positives = 66/200 (33%), Gaps = 57/200 (28%) Query: 1 MRILICGSHGQVALALQDALSGLGD--------------------VRRVGRDG-----LD 35 M+ L+ G+ G + + L G + + + G +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 36 LAHPEQLRATLRQIAPALIINAAAYTAVDQAESETRQAYTINAEAPRVLAE--------- 86 LA E + + + AV Y++ E P A+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAV---------RYSL--ENPHAYADSNLTGFLNI 109 Query: 87 -EAARLGAP--LIHYSTDYVFDGSKSAPYDEDD-TPSPLSVYGRSKLAGELAITAVAGEH 142 E R L++ S+ V+ ++ P+ DD P+S+Y +K A EL A H Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANEL--MAHTYSH 167 Query: 143 L------ILRTSWVYSHHGR 156 L LR VY GR Sbjct: 168 LYGLPATGLRFFTVYGPWGR 187
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 451 bits (1161), Expect = e-158 Identities = 184/482 (38%), Positives = 252/482 (52%), Gaps = 43/482 (8%) Query: 8 SRAQVLLVDDDPHLRQALSQTLDLAGLKVVALADAQGLAGRIEEDWPGVVVSDIRMPGID 67 + A +L+ DDD +R L+Q L AG V ++A L I +VV+D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 68 GLQLLEQLHARDSELPVLLITGHGDVPLAVQAMRAGAYDFLEKPFASDALLDSVRRALAL 127 LL ++ +LPVL+++ A++A GAYD+L KPF L+ + RALA Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 128 RRLVLDNRSLRLALSDRQQLATRLVGQSPGMQRLREQIGALAGTRADVLILGETGAGKEV 187 + L D Q LVG+S MQ + + L T ++I GE+G GKE+ Sbjct: 122 PK------RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKEL 175 Query: 188 VARALHDLSSRRDGPFVAINAGALAESVVESELFGHEPGAFTGAQKRRIGKFEFANGGTL 247 VARALHD RR+GPFVAIN A+ ++ESELFGHE GAFTGAQ R G+FE A GGTL Sbjct: 176 VARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTL 235 Query: 248 FLDEIESMSLDVQVKLLRLLQERVVERLGGNQLIPLDIRIIAATKEDLRQAADQGRFRAD 307 FLDEI M +D Q +LLR+LQ+ +GG I D+RI+AAT +DL+Q+ +QG FR D Sbjct: 236 FLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFRED 295 Query: 308 LYYRLNVAPLRIPALRERGDDILVLFQHFADAASERHGLPPHSLQPAQRAMLLRHDWPGN 367 LYYRLNV PLR+P LR+R +DI L +HF A E+ GL ++ H WPGN Sbjct: 296 LYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQA-EKEGLDVKRFDQEALELMKAHPWPGN 354 Query: 368 VRELQNAAERFAL-----------------------------------GLELALDGQVPA 392 VREL+N R + A++ + Sbjct: 355 VRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQ 414 Query: 393 AAHDIQVAVPTGNLSEQV-EQFERSLIAAELGQPHNSMRSLAEALGIPRKTLHDKLRKHG 451 A+P L ++V + E LI A L + A+ LG+ R TL K+R+ G Sbjct: 415 YFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG 474 Query: 452 LS 453 +S Sbjct: 475 VS 476
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 53.6 bits (129), Expect = 2e-10 Identities = 39/186 (20%), Positives = 76/186 (40%), Gaps = 28/186 (15%) Query: 7 LIVG-CGDVGSRLARQLLAQGWQVSGL------------RRSVDQLPE-GVRPIAADLAE 52 L+ G G +G ++++LL G QV G+ + ++ L + G + DLA+ Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLAD 63 Query: 53 PQIPSA-WPEQGPDYLVYCVA-ASQHDAAGYQAAYVEGLRHVLGWL----AAKGQRPRRL 106 + + + + + + + AY + ++ G+L + + + L Sbjct: 64 REGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD--SNLTGFLNILEGCRHNKIQHL 121 Query: 107 VFVSSSSVY-AQQDGEWIAEAAATQPEGYSGKVMLEAERLALGS----GIPATIVRLTGI 161 ++ SSSSVY + + + + P E +A G+PAT +R + Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 162 YGP-GR 166 YGP GR Sbjct: 182 YGPWGR 187
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 70.4 bits (172), Expect = 1e-16 Identities = 48/213 (22%), Positives = 82/213 (38%), Gaps = 1/213 (0%) Query: 10 RYGGSLAIVLGVHAVAVLLTLNWSVPQALELPPAAMMVELAPLPEPAPPPPPKAAPKPPT 69 R+ + + +H V L SV Q +ELP A + + + PP P P Sbjct: 13 RFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEP 72 Query: 70 PVEEPPMPKLAEAPKPKIAIPKPPKPKAKPQPPKPEKKLEPPKDEPPAKDDVADTPPSNT 129 VE P P+ P + + PKP KK+E PK + + +P NT Sbjct: 73 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENT 132 Query: 130 PPQKSAAPQPSIASNSNALPSWQSDLLRHLAKYKKYPEDARRRGLQGINRLRFVVDAEGK 189 P + + + A++ S S +YP A+ ++G +++F V +G+ Sbjct: 133 APARPTSSTATAATSKPV-TSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGR 191 Query: 190 VVSYALAGGSGSAALDRATLEMIRRAGTVPKPP 222 V + + + +R +RR P P Sbjct: 192 VDNVQILSAKPANMFEREVKNAMRRWRYEPGKP 224
>SECA#SecA protein signature. Length = 901 Score = 33.3 bits (76), Expect = 0.003 Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 17/140 (12%) Query: 273 AQQRVGNEIAYDLSQHEPMMRLVQGDV-----GAGKTVVAALAA-LQALEAGYQVALMAP 326 A +RV +D+ Q M L + + G GKT+ A L A L AL G V ++ Sbjct: 74 ASKRVFGMRHFDV-QLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL-TGKGVHVVTV 131 Query: 327 TEILAEQHYITFKRWLEPMGIEVAW-LAGKLKGKARASALEQIANGAPMVVGTHAL---- 381 + LA++ + E +G+ V L G R + I G G L Sbjct: 132 NDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNEYGFDYLRDNM 191 Query: 382 ---FQDEVQFKHLALAIIDE 398 ++ VQ + L A++DE Sbjct: 192 AFSPEERVQ-RKLHYALVDE 210
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 28.5 bits (64), Expect = 0.013 Identities = 6/29 (20%), Positives = 14/29 (48%) Query: 424 KDEIPDALLERLGLSREKAEEVVNKVLEA 452 K ++ + E L+++ + V+ V A Sbjct: 4 KQDLIAKVAEATELTKKDSAAAVDAVFSA 32
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 90.1 bits (224), Expect = 3e-27 Identities = 42/97 (43%), Positives = 61/97 (62%), Gaps = 10/97 (10%) Query: 3 KPELAAVIAEKADLTKEKANTVLNAILDSITTELGKKVKDKNGKETSPTVTLVGFGTFEK 62 K +L A +AE +LTK+ + ++A+ ++++ L G++ V L+GFG FE Sbjct: 4 KQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYL------AKGEK----VQLIGFGNFEV 53 Query: 63 RHRGARTGKNPQTGEPVKIKASNTVAFKPGKGLRDSV 99 R R AR G+NPQTGE +KIKAS AFK GK L+D+V Sbjct: 54 RERAARKGRNPQTGEEIKIKASKVPAFKAGKALKDAV 90