>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.2 bits (68), Expect = 0.006 Identities = 9/51 (17%), Positives = 24/51 (47%) Query: 138 LHAVDARVNELEELLPLLMKDKLLAKGVSHLLSSQLTRILRTHAAMSVLGH 188 + V+ +VN+ +P L + + +++ +S L +S + + A + Sbjct: 80 VSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSE 130
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 142 bits (361), Expect = 7e-40 Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 84/387 (21%) Query: 5 IGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58 + IDLGT N+ + + + E PS++A QD VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAE 118 P N + AI+ + +D I F + + Sbjct: 64 GRTPGN-IAAIRPM-----------KDGVIADFFVTEK------------------MLQH 93 Query: 119 VLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALA 178 +K++ + P ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 94 FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 179 YGL--DKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236 GL + TG+ V D+GGGT ++++I ++ V + +GG+ FD + Sbjct: 151 AGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAI 198 Query: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADATG 292 INY+ + G + AE+ K E+ SA + ++ + Sbjct: 199 INYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245 Query: 293 PKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIDD--VILVGGQTRMPMV 349 P+ + + LE+L E + + + VAL+ SDI + ++L GG + + Sbjct: 246 PRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303 Query: 350 QKKVAEFFGKEPRKDVNPDEAVAIGAA 376 + + E G +P VA G Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGG 330
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 61.4 bits (149), Expect = 4e-17 Identities = 18/46 (39%), Positives = 30/46 (65%) Query: 23 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 68 +++ ++++C+T ++ +TRK LCE+ R G EVA F AYES Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 30.7 bits (69), Expect = 0.002 Identities = 14/32 (43%), Positives = 19/32 (59%) Query: 8 NSAVLVHFTLKLDDGTTAESTRNNGKPALFRL 39 + V V +T L DGT +ST GKPA F++ Sbjct: 144 SDTVTVEYTGTLIDGTVFDSTEKAGKPATFQV 175
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 40.2 bits (94), Expect = 1e-05 Identities = 58/318 (18%), Positives = 106/318 (33%), Gaps = 27/318 (8%) Query: 31 GYVLVMIGVALEQLTPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDI 90 G ++ ++ L L + + A + LL L + G +SD+ GRR + L+ + Sbjct: 22 GLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFAC-APVLGALSDRFGRRPVLLVSL 80 Query: 91 IAIGVISVATMFVSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAM 150 V A M + + +L + ++ + GA +A + I + + +RA F++A Sbjct: 81 AGAAV-DYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSAC 139 Query: 151 WYVGATCADLVGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECE 210 + G ++G + + AA+ L L G F LPES KG + Sbjct: 140 FGFGMVAGPVLGGLMGGFSPHAPFFAA-AALNGLNFLTGCFLLPES-----HKGERRPLR 193 Query: 211 EMMIKLFGEPVAFDEEQPQQTRFRDLFNRRHFPFVLFVA-AIWTCQVIPMFAIYTFGPQI 269 + FR ++ V + +P FG Sbjct: 194 REALNPL-------------ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDR 240 Query: 270 VGLLGLGVGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLI 329 +G + A ++ SL + P L G R L+ +L Sbjct: 241 FHWDATTIGISLAAFGILHSLAQAMITGPVAARL---GERRALMLGMIADGTGYILLAFA 297 Query: 330 PDMGIWLVVMAFAVYAFF 347 W+ + A Sbjct: 298 TR--GWMAFPIMVLLASG 313
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.022 Identities = 26/118 (22%), Positives = 47/118 (39%), Gaps = 21/118 (17%) Query: 82 YGRHPEAREWYHQWVYFRPRAYWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQ-IINA 140 Y R PE +E + R YW + N P ++ +F+ + +F G ++ Sbjct: 158 YSRFPEVKELMESQMERLARPYWEKLRNRPDMY----YFKNYNFKRCYFGLNGGDCLVAK 213 Query: 141 G-----------QGEGRYSELLAINLLEQLLLRRMEA-----INESLHPPMDNRVREA 182 G QG +Y E + LE++L +++A I + +P +V A Sbjct: 214 GDDGRTFISFSLQGNSKYKEEMDAKKLEEILSLKVDANPDKYIKATGYPGYSEKVEVA 271
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 119 EVTEILVKVGDKV-EAEQSLITVEGDKASMEVPAPFAGTVKEIKVN-VGDKVSTGSLIMV 176 E+ + L + D + L E + + + AP + V+++KV+ G V+T +MV Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 31.7 bits (72), Expect = 0.008 Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAP 85 + V +T G S E+ + IVKEI V G+ + G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AQA 88 Q+ Sbjct: 139 TQS 141 Score = 30.6 bits (69), Expect = 0.019 Identities = 14/60 (23%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 220 EVTEVMVKVGDKVAA-EQSLITVEGDKASMEVPAPFAGVVKELKVN-VGDKVKTGSLIMI 277 E+ + + + D + L E + + + AP + V++LKV+ G V T +M+ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.8 bits (67), Expect = 0.035 Identities = 20/95 (21%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Query: 230 DKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAP 289 + VA +T G S E+ +VKE+ V G+ V+ G +++ GA A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE-ADTL 137 Query: 290 AKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAEND 324 Q + A + + + + E D Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.020 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 20/99 (20%) Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQL-L 164 V +E G L + V L AV GL P +V + D++G L Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSGHLLTQ 221 Query: 165 SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203 S+ + AQL V + +RI L+ P++G G Sbjct: 222 SNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 790 bits (2043), Expect = 0.0 Identities = 266/850 (31%), Positives = 425/850 (50%), Gaps = 38/850 (4%) Query: 15 RIATFCALLYCNSAFCAELVEYDHTFLMGQNASNIDLSRYSEGNPAIPGMYDLSVYVNDQ 74 R+ CA AE + ++ FL + DLSR+ G PG Y + +Y+N+ Sbjct: 29 RLFVACAFAAQAPLSSAE-LYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNG 87 Query: 75 PIINQSITFIEIEGKKNAQACITLKNLLQFHINSPDINNEKAVLLARDETLGNCLNLTKI 134 + + +TF + ++ C+T L +N+ + LLA D C+ LT + Sbjct: 88 YMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV--SGMNLLADDA----CVPLTSM 141 Query: 135 IPQASVRYDVNEQRLDIDVPQAWVMKNYQNYVDPSLWENGINAAMLSYNLNGYHSETP-G 193 I A+ + DV +QRL++ +PQA++ + Y+ P LW+ GINA +L+YN +G + G Sbjct: 142 IHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIG 201 Query: 194 RRNDSIYAAFNGGMNLGAWRLRASGNYNWMTDSGS-----NYDFKNRYIQRDIASLRSQL 248 + Y G+N+GAWRLR + +++ + S + N +++RDI LRS+L Sbjct: 202 GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRL 261 Query: 249 ILGESYTTGETFDSVSIRGIRLYSDSRMLPPTLASFAPIIHGVANTNAKVTITQGGYKIY 308 LG+ YT G+ FD ++ RG +L SD MLP + FAP+IHG+A A+VTI Q GY IY Sbjct: 262 TLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIY 321 Query: 309 ETTVPPGAFVIDDLSPSGYGSDLIVTVEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGG 368 +TVPPG F I+D+ +G DL VT++E+DGS + F+ P+SSV + R G R+ I+ G Sbjct: 322 NSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAG 381 Query: 369 QVLKDD-IQDEPNLFQASYYYGLNNYLTGYTGIQITDNNYTAGLLGLGLNT-SVGAFSFD 426 + + Q++P FQ++ +GL T Y G Q+ D Y A G+G N ++GA S D Sbjct: 382 EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVD 440 Query: 427 VTHSNVRIPDDKTYQGQSYRVSWNKLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVK 486 +T +N +PDD + GQS R +NK E+ T++ + YRYST Y D Sbjct: 441 MTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGY 500 Query: 487 HPE-----QDLEPKSMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASG 538 + E ++PK Y+ + ++ +++ Q L + YLSGS YW + Sbjct: 501 NIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTS 556 Query: 539 QNRSNYSIGYSNSASWGSYSVSAQRSWNE-DGDTDDSVYLSFTIPIEKLLGTEQRTS-GF 596 + G + + ++++S + N D + L+ IP L ++ ++ Sbjct: 557 NVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRH 616 Query: 597 QSIDTQMSSDFKGNNQLNVSSSGYS-DNARVSYSVNTGYTMNKASKDLSYVGGYASYESP 655 S MS D G G ++ +SYSV TGY S +Y Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 656 WGTLAGSVSANSDNSRQVSLSTDGGFVLHSGGLTFSNDSFSDSDTLAVVQAPGAQGARIN 715 +G S + D +Q+ GG + H+ G+T +DT+ +V+APGA+ A++ Sbjct: 677 YGNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVE 732 Query: 716 YGNST-IDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSAVAVPRQGSVVFADFET 774 D GY V + Y ENR+ALD N L ++V+L + A VP +G++V A+F+ Sbjct: 733 NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA 792 Query: 775 VQGQSAIMNITRSDGKNIPFAADIYDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEES 834 G +M +T + K +PF A + E G V GQ ++ G+ G + +KW EE Sbjct: 793 RVGIKLLMTLTH-NNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEE 851 Query: 835 KPVSCLAHYQ 844 C+A+YQ Sbjct: 852 NA-HCVANYQ 860
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 510 bits (1315), Expect = 0.0 Identities = 294/296 (99%), Positives = 295/296 (99%) Query: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPDMLARIAPGR 120 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSP+MLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 DNSKDMDALMATPLWQAMPFVRTGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296 DNSKDMDALMATPLWQAMPFVR GRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 34.3 bits (78), Expect = 4e-04 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236 + ++ EL A N T+ +K ++N+ +R D + I V +E+++++ Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 27.3 bits (60), Expect = 0.008 Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 45 AVYKDHPLQSSWKGYRDAHVEPD 67 +VYK + + G+ A V Sbjct: 153 SVYKAFSDRVTLPGFNSAKVTSL 175
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 38.4 bits (89), Expect = 2e-05 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 22/118 (18%) Query: 116 FERGSAQIMPFFKTLLVELAPVFDSL---DNKIIITGHTDAM---AYKNNIYDNWNLSGD 169 F A + P + L +L +L D +++ G+TD + AY N LS Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAY------NQGLSER 276 Query: 170 RALSARRVLEEAGMPEDKVMQVS-----AMADQMLLDSKNPQS-----AGNRRIEIMV 217 RA S L G+P DK+ + + K + A +RR+EI V Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 6e-05 Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 17/127 (13%) Query: 119 DTLRALLDNNI---------VPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLT 169 +T++ L++ + VPVI E+ + E V D D A AD ++LT Sbjct: 177 ETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILT 235 Query: 170 DQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAA-DVACRAG 228 D G + + +++V +++ + G M K+ AA G Sbjct: 236 DVNGAALY--YGTEKEQWLREV-KVEELRKYYEEG---HFKAGSMGPKVLAAIRFIEWGG 289 Query: 229 IDTIIAA 235 IIA Sbjct: 290 ERAIIAH 296 Score = 30.2 bits (68), Expect = 0.013 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 4 SQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQ----LHAAGHRIVIVTSG-------- 51 + +V+ LG + L ++ + +++ VR+ A+ + A G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 52 -AIAAGREHLGYPELP 66 + AG+ G P P Sbjct: 62 LHMDAGQATYGIPAQP 77
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 63.3 bits (154), Expect = 3e-12 Identities = 30/247 (12%), Positives = 72/247 (29%), Gaps = 23/247 (9%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGPFGSLGLRAGIQRYNNGDSN 546 L + + T +S + Y + +Q + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFNTGLED---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G +D + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLD 718 + + + Sbjct: 762 TNTLADN 768
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.023 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 3 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 44 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.9 bits (155), Expect = 6e-15 Identities = 31/172 (18%), Positives = 58/172 (33%), Gaps = 15/172 (8%) Query: 10 RRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLR 69 R+ ++D L ++ G+ ++ +IA+ AGV+ G I +F+DK+ L S + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 DAVLNRLHALPQGSAELRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQP-------ML 122 + L P L+ I+ + T V+ + + Sbjct: 72 ELELEYQAKFPGDPLS-VLREILIHVLEST-VTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 123 YRLQQVSSRRLLSNLVSEFRRE---LPRHQAQEAGYGLAALIDGL---WLRA 168 R + S + + + A + I GL WL A Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.009 Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 6 TEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRMETGLDVVLFTRS 55 E L+ A G+ KAA+ LGL + + I+ + G+ V +RS Sbjct: 436 MEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL--GVSVYRSSRS 483
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 339 bits (872), Expect = e-114 Identities = 122/401 (30%), Positives = 200/401 (49%), Gaps = 54/401 (13%) Query: 164 DLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSP 223 A +A G + Y ++ + + +L ++ ++G+S Sbjct: 88 MTAIKASEKGAYDYLPKPFDL--TELIGIIGRALAEPKRRPSK-LEDDSQDGMPLVGRSA 144 Query: 224 QMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNC 283 M+++ + + ++ ++I GE+GTGKEL A+A+H + R+ PFVA+N Sbjct: 145 AMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD-----YGKRRNG---PFVAINM 196 Query: 284 GAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVL 343 AI L+E+ELFG+E+GAFTG++ G FE A GGTLFLDEIG+MP+ QTRLLRVL Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVL 255 Query: 344 EEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGQFRRDLFYRLSILRLQLPPLRERVA 403 ++ E T VGG P+ DVR+++AT+ +L++ + QG FR DL+YRL+++ L+LPPLR+R Sbjct: 256 QQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAE 315 Query: 404 DILPLAESFLKVSLAALSTPFSAALRQGLQASETVLVHYDWPGNIRELRNMMERLALFLS 463 DI L F++ ++ L+ + + WPGN+REL N++ RL Sbjct: 316 DIPDLVRHFVQ-QAEKEGLDVKRFDQEALEL----MKAHPWPGNVRELENLVRRLTALYP 370 Query: 464 VEP-TPDLTPQFLQLLLPELARESAKTPAPRLLTP------------------------- 497 + T ++ L+ +P+ E A + L Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYD 430 Query: 498 -----------QQALEKFNGDKTAAANYLGISRTTFWRRLK 527 AL G++ AA+ LG++R T ++++ Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIR 471
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.022 Identities = 11/33 (33%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 65 LIHGKLPTRDE-LAAYKTKLKALRGLPANVRTV 96 + +LPT +E AYK ++ + G P +RT+ Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTL 335
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 30.3 bits (68), Expect = 0.006 Identities = 24/129 (18%), Positives = 53/129 (41%), Gaps = 22/129 (17%) Query: 82 FYANFN----LTIVDDYTVTIGDNVLIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNN 137 F A+F ++ + + V+I P+V ++T +++ + Y F +++ + Sbjct: 30 FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTIT--VRSYDMLNEEQYYQFFLSV-LD 86 Query: 138 VWIGSHVVINPGVTI---------------GDNSVIGAGSIVTKDIPPNVVAAGVPCRVI 182 V+ + + +N GV D + +VT+ +P VAA ++ Sbjct: 87 VYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLL 146 Query: 183 REINDRDKH 191 R++ND Sbjct: 147 RQLNDNAGV 155
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 3e-04 Identities = 44/192 (22%), Positives = 72/192 (37%), Gaps = 22/192 (11%) Query: 4 LKNTNFWMFGLFFFFYFFI-MGAYFPFFPIWLHDINHISK--SDTGIIFAAISLFSLLFQ 60 +K + L + +G P P L D+ H + + GI+ A +L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 61 PLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYNILVGSIVGGIYLGFCFNA 120 P+ G LSD+ G R LL + + I P L + + +G IV GI A Sbjct: 61 PVLGALSDRFGRRPVLL---VSLAGAAVDYAIMATAPFL-WVLYIGRIVAGIT-----GA 111 Query: 121 GAPAVEAFIEKVSRRSNFEFGRARMFG----CVGWALCAS--IVGIMFTINNQFVFWLGS 174 A+I ++ RAR FG C G+ + A + G+M + F+ + Sbjct: 112 TGAVAGAYIADITDGDE----RARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAA 167 Query: 175 GCALILAVLLFF 186 + + F Sbjct: 168 ALNGLNFLTGCF 179
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 29.3 bits (65), Expect = 0.025 Identities = 18/69 (26%), Positives = 30/69 (43%) Query: 254 DIVRELRERTELPIGAYQVSGEYAMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYF 313 + EL + +L + QV G A F +D E L I+ A +IF+ Sbjct: 466 NQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGK 525 Query: 314 AMDLAEKKI 322 ++L E++I Sbjct: 526 DLNLVERRI 534
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 124 bits (312), Expect = 4e-31 Identities = 102/442 (23%), Positives = 171/442 (38%), Gaps = 59/442 (13%) Query: 578 TINGNGDVDNGTELDNSSVDNVVA---ATGNYKVRIDNATGAGAIADYKDKEIIYVNDVN 634 T+ G+G D D +V A+G +++ + N+ G+ + ++ + Sbjct: 477 TLAGSGLFRMNVFADLGLSDKLVVMQDASGQHRLWVRNS---GSEPASANTLLLVQTPLG 533 Query: 635 SNATFSAAN---KADLGAYTYQAEQRGNTV------------------------------ 661 S ATF+ AN K D+G Y Y+ GN Sbjct: 534 SAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQP 593 Query: 662 ------VLQQMELTDYANMALSIP--SANTNIWNLEQDTVGTRLTNSRHGLADNGGAWVS 713 EL+ AN A++ + +W E + + RL R D GGAW Sbjct: 594 EAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRL-NPDAGGAWGR 652 Query: 714 YFGGNFNGDNGTIN-YDQDVNGIMVGVDTKIDGNNAKWIVGAAAGFAKGDMN---DRSGQ 769 F DN +DQ V G +G D + +W +G AG+ +GD D G Sbjct: 653 GFAQRQQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGH 712 Query: 770 VDQDSQTAYIYSSAHFANNVF-VDGSLSYSHFNNDLSATMSNGTYVDGSTNSDAWGFGLK 828 D Y + + A++ F +D +L S ND S+G V G + G L+ Sbjct: 713 TDSVHVGGY---ATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLE 769 Query: 829 AGYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNDMKVDGQSYDSMRYELGVDAGYTFTYS 888 AG F D ++ P ++ G Y+ +N ++V + S+ LG++ G + Sbjct: 770 AGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELA 829 Query: 889 EDQALTPYFKLAYVYDDSNNDNDVNGDSIDNGTEGSAVRV--GLGTQFSFTKNFSAYTDA 946 + + PY K + + + + V+ + I + TE R GLG + + S Y Sbjct: 830 GGRQVQPYIKASVL-QEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASY 888 Query: 947 NYLGGGDVDQDWSANVGVKYTW 968 Y G + W+ + G +Y+W Sbjct: 889 EYSKGPKLAMPWTFHAGYRYSW 910
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.8 bits (67), Expect = 0.030 Identities = 31/137 (22%), Positives = 54/137 (39%), Gaps = 24/137 (17%) Query: 245 IWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQDAIENRDICVHYQPIVSLANGKIVGAEA 304 W+ L L+ G +A +LR R+ + + P++ G+I Sbjct: 228 PWMLLALLAGFMAFRVMLR------QEKRRVS-----FHRRLLHLPLI----GRIARGLN 272 Query: 305 LARWPQTDGSWLSPDSFIPLAQQTGLS-EPLTLLIIRSVFEDMGDWLRQHPQQHISINLE 363 AR+ +T + S +PL Q +S + ++ R D +R+ H + LE Sbjct: 273 TARYARTLSILNA--SAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVSLHKA--LE 328 Query: 364 STVLTSEKIPQLLREMI 380 T L P ++R MI Sbjct: 329 QTAL----FPPMMRHMI 341
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3546), Expect = 0.0 Identities = 802/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 6e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 100 TYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 159 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 8e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 49 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDS 107 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 167 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 168 RINLA 172 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 222 bits (567), Expect = 5e-76 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 4e-05 Identities = 40/251 (15%), Positives = 77/251 (30%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALS-MLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 27.8 bits (62), Expect = 0.047 Identities = 11/43 (25%), Positives = 18/43 (41%) Query: 38 GQLAAVAIVTCDGNVYSAGDSDYRFALESISKVCTLALALEDV 80 G++ + + G +A +D RF + S KV L V Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.0 bits (189), Expect = 9e-19 Identities = 48/212 (22%), Positives = 81/212 (38%), Gaps = 7/212 (3%) Query: 16 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNN----MGFT--GVLIDLDS 69 K ITG + GIG A L QG H+ A P+ +E++ + D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 189 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 55.1 bits (133), Expect = 3e-10 Identities = 39/163 (23%), Positives = 59/163 (36%), Gaps = 32/163 (19%) Query: 4 DLIIKNGTVILENEARVVDIAVKGGKIAAIG-------QD-----LGDAKEVMDASGLVV 51 D +I N ++ DI +K G+IAAIG Q +G EV+ G +V Sbjct: 69 DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 52 SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104 + G +D+H H P + A G+T M+ PA A+ Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177 Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146 I +AA ++ A G + L E+ G K Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 387 bits (995), Expect = e-138 Identities = 126/310 (40%), Positives = 176/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PPVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTEDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPKVTAVSGYVRSRGKPAWIGALSRIEE 285 +GT +++ +R +EL + + GSMGPKV A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.030 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353 + ++ +L QAR R R + P E F +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 826 bits (2134), Expect = 0.0 Identities = 404/856 (47%), Positives = 574/856 (67%), Gaps = 20/856 (2%) Query: 20 ICYSSLAILPSFLSYAESYFNPAFLLENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFI 79 + A + LS AE YFNP FL ++ +VADLSRFE G P G YRVD++ N+ ++ Sbjct: 31 FVACAFA-AQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 80 GSQDIVFESTTENTGDKSGGLMPCFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPD 139 ++D+ F NTGD G++PC + L +GLN+++ + ++ C+ L + D Sbjct: 90 ATRDVTF-----NTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 140 ATINFDFAAMRLNITIPQIALLSSAHGYIPPEEWDEGIPALLLNYNFTGN----RGNGND 195 AT D RLN+TIPQ + + A GYIPPE WD GI A LLNYNF+GN R GN Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 196 SYFFSEL-SGINIGPWRLRNNGSWNYFRGNG--YHSEQWNNIGTWVQRAIIPLKSELVMG 252 Y + L SG+NIG WRLR+N +W+Y + +W +I TW++R IIPL+S L +G Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 253 DGNTGSDIFDGVGFRGVRLYSSDNMYPDSQQGFAPTVHGIARTAAQLTIRQNGFIIYQSY 312 DG T DIFDG+ FRG +L S DNM PDSQ+GFAP +HGIAR AQ+TI+QNG+ IY S Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 313 VSPGAFEITDLHPTSSNGDLDVTIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFR 372 V PG F I D++ ++GDL VTI E DG+ Q +T+PYS+VP+LQREG ++ +TAG++R Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 373 SGNSQQSSPFFFQGTALGGLPQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHA 432 SGN+QQ P FFQ T L GLP +T YGGTQL+ Y AF G+G+N+G GA+S+D+T A Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQA 444 Query: 433 RSQLADDSRHEGDSIRFLYAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDY 492 S L DDS+H+G S+RFLY KS+N GTN QL+GYRYST G++ D Y RM GY Sbjct: 445 NSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGY-NIE 503 Query: 493 DYDGEHRDEPIIVNYHNLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQ 552 DG + +P +Y+NL ++++ +LQL ++Q L +LY+SG+HQ YW TS+ D +Q Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQ 563 Query: 553 VGYTSSWVGISYSLSFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASF 612 G +++ I+++LS+S ++ ++++ LNV++PF+ R ++ A AS+ Sbjct: 564 AGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWL--RSDSKSQWRHASASY 621 Query: 613 NANRNSNGQNSWLAGVGGTLLEGHNLSYHVSQG----DTSNNGYTGSATANWQAAYGTLG 668 + + + NG+ + LAGV GTLLE +NLSY V G N+G TG AT N++ YG Sbjct: 622 SMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNAN 681 Query: 669 VGYNYDRDQHDVNWQLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDW 728 +GY++ D + + +SGGV+ H NG+TL QPL DT VL+KAPGA ++ENQTG+ TDW Sbjct: 682 IGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDW 741 Query: 729 RGYAVMPYATVYRYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALIT 788 RGYAV+PYAT YR NR+ALDTNT+ +++D++ +++VVPT+GA+VRA F R+G++ L+T Sbjct: 742 RGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMT 801 Query: 789 VTQGGKPVPFGSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVL 848 +T KP+PFG++V S+ + +V D+GQVYLSG PL+G++ V+WG+ N+ C+A+Y L Sbjct: 802 LTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQL 861 Query: 849 PKQSLQQAVTVISAVC 864 P +S QQ +T +SA C Sbjct: 862 PPESQQQLLTQLSAEC 877
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 4e-13 Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Query: 1 MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLP 60 M ++++ D IR + L + V T + ++ DL++ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMI 120 + F L RIK+ + + VL +S+++ A +A + GA ++ K D ++ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LS 122 L+ Sbjct: 119 LA 120
>PF06291#Lambda prophage Bor protein Length = 102 Score = 176 bits (446), Expect = 2e-61 Identities = 96/97 (98%), Positives = 97/97 (100%) Query: 1 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQEKTVDAAKICGG 60 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQ+KTVDAAKICGG Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65 Query: 61 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 97 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ Sbjct: 66 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 4e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLMKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 273 bits (698), Expect = 7e-96 Identities = 106/183 (57%), Positives = 130/183 (71%), Gaps = 1/183 (0%) Query: 1 MKTTHTSLPFAGHTLHFVEFDPANFCEQDLLWLPHYAQLQHAGRKRKTEHLAGRIAAVYA 60 M T+H LPFAGH LH V+FD ++F E DLLWLPH+ +L+ AGRKRK EHLAGRIAAV+A Sbjct: 1 MLTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA 60 Query: 61 LREYGYKCVPAIGELRQPVWPAEVYGSISHCGTTALAVVSRQPIGIDIEEIFSVQTAREL 120 LRE G + VP +G+ RQP+WP ++GSISHC TTALAV+SRQ IGIDIE+I S TA EL Sbjct: 61 LREVGVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISRQRIGIDIEKIMSQHTATEL 120 Query: 121 TDNIITPAEHERLADCGLAFSLALTLAFSAKESAFKA-SEIQTDAGFLDYQIISWNKQQV 179 +II E + L L F LALTLAFSAKES +KA S+ T GF ++ S + Sbjct: 121 APSIIDSDERQILQASLLPFPLALTLAFSAKESVYKAFSDRVTLPGFNSAKVTSLTATHI 180 Query: 180 IIH 182 +H Sbjct: 181 SLH 183
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.3 bits (84), Expect = 2e-04 Identities = 82/394 (20%), Positives = 145/394 (36%), Gaps = 38/394 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMP 309 A IG AA L + A+ +G +A ++L + ++ + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELRR 403 + A + + +G+ + L LL L LRR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALRR 387
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 62.3 bits (151), Expect = 3e-13 Identities = 56/266 (21%), Positives = 96/266 (36%), Gaps = 35/266 (13%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYAL 295 KD DA+ A PL +P V+ + + Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRV 269
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 443 bits (1141), Expect = e-160 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPKSHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 363 bits (932), Expect = e-130 Identities = 108/258 (41%), Positives = 149/258 (57%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------------QAFTQEQYPFATE 49 GK ++TGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAGQVAQVCQRLLAETERLDVLINAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+ + ++ R+ E +D+L+N AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 97.1 bits (242), Expect = 4e-24 Identities = 78/342 (22%), Positives = 131/342 (38%), Gaps = 32/342 (9%) Query: 8 IGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIISMDENNH------ILVGKPAVSRR 61 + IDLGT N+LI V K L PS++++ ++ VG A Sbjct: 13 LSIDLGTANTLIYV-KGQGIVLN--------EPSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 62 TSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSLKEDAEEFLQRPIKDVVISV 121 P AA+ R M +D F ++ ++ + ++ RP V++ V Sbjct: 64 GRTPGNIAAI--RPMKDGVI----ADFFVTEKMLQHFIKQVHSNS---FMRPSPRVLVCV 114 Query: 122 PAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGLHTQQNTRSLVFDLGGGTFDVT 181 P + +R+ R +A+ AG V LI EP AAA+ GL + T S+V D+GGGT +V Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA 174 Query: 182 VLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRADVARTTLNESELAALYACVEAAK 241 V+ V + +GG+ F +++ V + + Sbjct: 175 VISLNGVVY-----SSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGD 229 Query: 242 CSNQSPMHIRWQYQDEARECDFYENELEDLWLPLLNRLRVPIEQALRDA--RLKPSQID- 298 + + R + R NE+ + L + + AL L + Sbjct: 230 EVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISER 289 Query: 299 SLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIVALGAAI 340 +VL GG + + + R+ + G + DP T VA G Sbjct: 290 GMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 7e-24 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATTAP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.011 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 785 LLENAVKYAGAQAE----IGIDAHVEGENLQLDVWDNGPGLPPGQEQT 828 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 603 bits (1557), Expect = 0.0 Identities = 237/859 (27%), Positives = 383/859 (44%), Gaps = 63/859 (7%) Query: 8 FVSCLVMAMPCAL--AVEFNLNVLDKSMRDRIDISLLKEKGVIAPGEYFVSVAVNNNQIS 65 FV+C A + FN L + D+S + + PG Y V + +NN ++ Sbjct: 31 FVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMA 90 Query: 66 NGQ-KINWQKKGDKTIPCINDSLVDKFGLKPDIRQSLPQI--DRCIDFSSR-PEMLFNFD 121 N +PC+ + + GL + + D C+ +S + D Sbjct: 91 TRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLD 150 Query: 122 QANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVLMDYNLFASNYRPQDGSSSTNLNAY 181 Q+LN++IPQA+++ + + PP W G+ L++YN ++ + + G +S Sbjct: 151 VGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLN 210 Query: 182 GTTGINAGSWRLRSDYQLNNTDSEDSHEQSGGI--SRTYLFRPLPQLGSKLTLGETDFSS 239 +G+N G+WRLR + + S+ S T+L R + L S+LTLG+ Sbjct: 211 LQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQG 270 Query: 240 NIFDGFSYTGAALASDDRMLPWELRGYAPQISGIAQTNATVTISQSGRVIYQKKVPPGPF 299 +IFDG ++ GA LASDD MLP RG+AP I GIA+ A VTI Q+G IY VPPGPF Sbjct: 271 DIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPF 330 Query: 300 IIDDLNQ-SVQGTLDVKVTEEDGRVNNFQVSAASTPFLTRQGQVRYKLAAGQPRPSMSHQ 358 I+D+ G L V + E DG F V +S P L R+G RY + AG+ R + Q Sbjct: 331 TINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSG-NAQ 389 Query: 359 TENETFFSNEVSWGMLSNTSLYGGLLLSGDDYHSAAMGIGQNMLWLGALSFDVTWASSHF 418 E FF + + G+ + ++YGG L+ D Y + GIG+NM LGALS D+T A+S Sbjct: 390 QEKPRFFQSTLLHGLPAGWTIYGGTQLA-DRYRAFNFGIGKNMGALGALSVDMTQANSTL 448 Query: 419 DTQQDERGLSYRFNYSKQVDATNSTISLAAYRFSDRHFHSYANYLDHKYND--------- 469 G S RF Y+K ++ + + I L YR+S + ++A+ + N Sbjct: 449 PDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV 508 Query: 470 -----------SDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWNADASTTANITAGF 518 + A +++ + L+V Q + LY + HQT+W AG Sbjct: 509 IQVKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYWGTSNVDE-QFQAGL 566 Query: 519 NVDIGDWRDISISTSFNTTHYE-DKDRDNQIYLSISLPFGNGGR-----------VGYDM 566 N + DI+ + S++ T K RD + L++++PF + R Y M Sbjct: 567 NT---AFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSM 623 Query: 567 QNSSHS-TTHRMSWNDTLDERN--SWGMSAGL-QSDRPDNGAQVSGNYQHLSSAGEWDIS 622 + + T+ TL E N S+ + G ++G+ + G +I Sbjct: 624 SHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIG 683 Query: 623 GTYAANDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY-TN 681 ++ ++D + SG A G + N+ ++V G D V+ T+ Sbjct: 684 YSH-SDDIKQLYYGVSGGVLAHANGVTLGQP--LNDTVVLVKAPGAKDAKVENQTGVRTD 740 Query: 682 HFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGKDVNV 741 G AV+P + Y+ + VA++ N L D V + V GAI +R G + + Sbjct: 741 WRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLM 800 Query: 742 IIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQKFTVVWG--DSQHCSLH 799 + + + P GA + +S S G+V + G +LSG+ K V WG ++ HC + Sbjct: 801 TLT-HNNKPLPFGAMV-TSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVAN 858 Query: 800 --LPEH-MEDTANRLILPC 815 LP + +L C Sbjct: 859 YQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 34.6 bits (79), Expect = 9e-05 Identities = 43/179 (24%), Positives = 74/179 (41%), Gaps = 26/179 (14%) Query: 14 SLLFTAPVYAADEGSGEIHFKGEVIEAPCEIHQDDIDKEVELGQVTTSHINQS-HHSDAV 72 ++L + V+AAD + FKG++I C + + EV G + ++ QS + Sbjct: 15 AVLMSQHVHAADN----LTFKGKLIIPACTVQ----NAEVNWGDIEIQNLVQSGGNQKDF 66 Query: 73 AVDLRLVNCDLENSSNGSGGKISKVAVTFDSSAKTTGADPILNNTSTGEATGVGVRLMNK 132 VD+ NC + + VT S+ TG ++ NTST G+ + L N Sbjct: 67 TVDM---NCPYS---------LGTMKVTITSNG-QTGNSILVPNTSTASGDGLLIYLYNS 113 Query: 133 DQSNI----VLGTATPDIDLAPTSSEQTLNFFAWMEQIDQATPVTPGAVTANATYVLDY 187 + S I LG+ + T+ + + +A + + G +A AT V Y Sbjct: 114 NNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASY 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.4 bits (71), Expect = 0.003 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEAEEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%) Query: 48 EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106 E+ + I+ ++ EG +V +L +L + +S +A R Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158 + L P + + T ++ E +L K A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 APAAAAPAAQPALAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215 A + + + L + A +LE +N V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 216 LRKQYGEAFEKRHGIR 231 + + A E+ + Sbjct: 278 IESEILSAKEEYQLVT 293
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.1 bits (145), Expect = 9e-12 Identities = 34/199 (17%), Positives = 69/199 (34%), Gaps = 8/199 (4%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158 E E+ Q QA+ + E A A ++ E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 159 AAK--KAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAA--AAEARKKAATE 214 A+ K + +K E +A + A+ ++ A+ A + +K + E A +E ++ TE Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 215 AAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 274 E A E E+KA E + + K+ + +A ++ + + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 275 AAAAKAAAEKAAAAKAAAE 293 + A + A + ++ Sbjct: 1160 SQTNTTADTEQPAKETSSN 1178 Score = 57.0 bits (137), Expect = 9e-11 Identities = 30/236 (12%), Positives = 85/236 (36%), Gaps = 11/236 (4%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAA 180 + ++ A+EA + A+ A++ +E E + A + ++KA+ E K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 181 EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240 + ++ + ++++E + A AR+ T ++ +++ A E+ A + + Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 241 EKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADD 296 E+ + + + A ++ K + ++ + Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Score = 56.2 bits (135), Expect = 2e-10 Identities = 28/228 (12%), Positives = 75/228 (32%), Gaps = 2/228 (0%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAK--KAAADAKKKAEAEAAKAAAEAQ 183 +++ KQ + + A+ + + E ++ A + E + + Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 184 KKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKA 243 ++ + E A + + + K + ++ ++ +++ Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Query: 244 AADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 291 +D +A A+ A + A ++ ++ + Sbjct: 1246 TVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 55.5 bits (133), Expect = 2e-10 Identities = 32/265 (12%), Positives = 86/265 (32%), Gaps = 14/265 (5%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163 + E + ++ ++ Q K+ +K+ KA + + E ++ + K+ Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----EKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 164 AADA-KKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAE 222 ++ + +AE K+ ++ + A+ ++ + Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 223 AEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAA 282 + A + +++ K + + + + A + A + Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254 Query: 283 EKAAAAKAAAEADDIFGELSSGKNA 307 A + A A F L+ GK Sbjct: 1255 TNTNAVLSDARAKAQFVALNVGKAV 1279
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (292), Expect = 5e-34 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 4/119 (3%) Query: 55 EEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSN--PSYKVTVEGHADER 112 +Q + + V F+ +K ++ + LD + L + V V G+ D Sbjct: 205 APAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI 264 Query: 113 GTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDEAAYSKNRRAVL 171 G+ YN L ERRA +V YL KG+ AD+IS G+ P V G+ K R A++ Sbjct: 265 GSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCDNVKQRAALI 321
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.025 Identities = 14/72 (19%), Positives = 28/72 (38%), Gaps = 4/72 (5%) Query: 24 AFAQAPISSVGSGSVEDRVTQLERISNAHSQLLTQLQQQLS---DNQSDIDSLRGQIQEN 80 F I +G+ + D +++ H L Q L + + + S+R E+ Sbjct: 664 PFNMPAIVELGTATGFD-FELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLED 722 Query: 81 QYQLNQVVERQK 92 Q V+++K Sbjct: 723 TAQFKLEVDQEK 734
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.025 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 218 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFTGGWFI 275 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 276 DRYSRVAVVR-ASALM--GALGIGLIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 331 DR + V+ + L ++ S ++ + VL GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 332 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 361 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 4e-10 Identities = 14/81 (17%), Positives = 31/81 (38%) Query: 2 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFS 61 + + R+ I+ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 62 SFTEIMSRQYQAFFSDVSDAP 82 + + + P Sbjct: 65 LSESNIGELELEYQAKFPGDP 85
>PF06872#EspG protein Length = 398 Score = 25.8 bits (56), Expect = 0.048 Identities = 9/27 (33%), Positives = 21/27 (77%) Query: 20 TLRITVTDVDIVDGEDDSPDDELFYLV 46 +LRI+VT+ ++++ E +P++E F ++ Sbjct: 104 SLRISVTNSELIEAEIHTPNNEKFLVL 130
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 29.8 bits (67), Expect = 0.047 Identities = 27/183 (14%), Positives = 61/183 (33%), Gaps = 23/183 (12%) Query: 450 WPRAAENELKK-AEVIEPRNINLEVEQAWTALTLQEWQQA--AVLTHDVVEREPQDPGVV 506 + A E + A +++ + +E + + L ++ ++E E + + Sbjct: 47 YLEVARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTI 106 Query: 507 -RLK---RAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYS---PPLKDNWRGFA 559 LK ++ + N+ I+G E + DL P+ + F Sbjct: 107 NLLKDYFSSLTIDNMISKMISGVVT--EELKNYTSSLDDLVNGANLFIIDPMPNVL--FT 162 Query: 560 GFGYADGQFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDN 619 D S G G+ + + + R E +AE +F + + W + + Sbjct: 163 ----RDPFASIGNGVT---INKMFTKVRQ--RETIFAEYIFKYHPVYKENVPIWLNRWEE 213 Query: 620 WRI 622 + Sbjct: 214 ASL 216
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 29.6 bits (66), Expect = 0.027 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 6/77 (7%) Query: 335 DQVIKTVVNIIGKSIRPDDLLA--RVGGEEFGVLLTDIDTERAKALAERIRENVERLTGD 392 D + + N + + P +L+ R G +EFG+ LT + + K E I E+ G Sbjct: 313 DSKVNNIENALKLTPIPSNLIVYRRSGPQEFGLTLTSPEYDFNK--IENIDAFKEKWEGK 370 Query: 393 NPEYAIPQKVTISIGAV 409 Y P ++ SIG+V Sbjct: 371 VITY--PNFISTSIGSV 385
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.9 bits (98), Expect = 4e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 353 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 401 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 37.2 bits (86), Expect = 9e-05 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 349 bits (897), Expect = e-126 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 427 bits (1100), Expect = e-152 Identities = 157/363 (43%), Positives = 213/363 (58%), Gaps = 9/363 (2%) Query: 4 FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63 F + L A RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 64 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 299 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 360 AKL 362 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 511 bits (1318), Expect = 0.0 Identities = 313/313 (100%), Positives = 313/313 (100%) Query: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 684 bits (1766), Expect = 0.0 Identities = 545/546 (99%), Positives = 545/546 (99%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 361 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSTTQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSS TQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.4 bits (107), Expect = 2e-07 Identities = 41/226 (18%), Positives = 80/226 (35%), Gaps = 9/226 (3%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAGYKTETAPFSEANGDYVGGTESIKQQVDASRSMVIGHTGDKIFDSITSN 186 T NG + + +G E+I + +G G + + Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232 + T A + + TA DK Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 64.7 bits (157), Expect = 2e-12 Identities = 47/288 (16%), Positives = 84/288 (29%), Gaps = 36/288 (12%) Query: 513 PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAAPVVAPAPKSAPATPAAPAQPGLL 571 P E+ + DVP P+ E A AP P APATP+ Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETT----- 1037 Query: 572 SRFFGALKALFSGGEETKPSEQPTPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSER-- 629 ET + Q QN + + + ++ Sbjct: 1038 ---------------ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 630 TEGSDNREENRRNRRQAQQQTAETRESRQQVEVTEKARTTDEQQAPRRERSRRRNDDKRQ 689 E + + E + + ++TA + + TEK + + + + + + Q Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 690 AQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEEAVVAPV 744 A+ + +N++E Q + +P + + Q V +V V P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 745 VEETVAAEPIVQEAPA------PRTELVKVPLPVVAQTAPEQQEENNA 786 +P V + R + VP V T A Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.7 bits (100), Expect = 4e-06 Identities = 30/115 (26%), Positives = 57/115 (49%), Gaps = 7/115 (6%) Query: 387 GTTTLKLSENTIWNMKDDSVVTHLTNSDSIINL-SYDDGQTFTQGKTLTVKGNYVGNNGQ 445 G + ++L+EN+ W++ +S V L ++ I+L S D+ T+ TLTV N + NG Sbjct: 842 GNSQVRLTENSHWHLTGNSDVHQLDLANGHIHLNSADNSNNVTKYNTLTV--NSLSGNGS 899 Query: 446 LNIRTVLGDDKSATDRLIVEGNTSGSTTVYVKNAGGSGAATLNGIELITVNGDES 500 T L + + D+++V + +G+ T+ V + G N + L + + Sbjct: 900 FYYLTDLSNKQG--DKVVVTKSATGNFTLQVADKTGE--PNHNELTLFDASKAQR 950
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 63.5 bits (154), Expect = 5e-13 Identities = 82/373 (21%), Positives = 125/373 (33%), Gaps = 63/373 (16%) Query: 3 AGAFEYQLKQQGK-NWYLTSYQSVNEEDNSSEGNSEST-------ETPTPVLRPEAGSYV 54 G + Y+L G W L ++ + + + E P P Sbjct: 549 IGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSA 608 Query: 55 ANLAAANTLFVMRLNDRAGETRYIDPVTEQERSSRLWLRQIGGHNAWRDSNGQLRTTSHR 114 A AA NT V A Y + +R L L G AW Q + +R Sbjct: 609 AANAAVNTGGV----GLASTLWYAESNALSKRLGELRLNPDAG-GAWGRGFAQRQQLDNR 663 Query: 115 Y-------VS--QLGGDLLTGGFTDSDSWRLGVMAGYARDYNLTHSSVSDYRSKGSVRGY 165 V+ +LG D W LG +AGY R + G Sbjct: 664 AGRRFDQKVAGFELGADHAVAVAGGR--WHLGGLAGYTR----GDRGFTGDGG-GHTDSV 716 Query: 166 SAGLYATWFADDISKKGAYIDSWAQYSWFKN----------SVKGDELAYESYSAKGATV 215 G YAT+ AD G Y+D+ + S +N +VKG Y G Sbjct: 717 HVGGYATYIADS----GFYLDATLRASRLENDFKVAGSDGYAVKGK------YRTHGVGA 766 Query: 216 SLEAGYGFALNKSFGLEAAKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNIQTR 275 SLEAG F W +PQA+ A+ ANG R+ ++ +++ R Sbjct: 767 SLEAGRRFTHADG---------WFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGR 817 Query: 276 LGFRTFIRTQEKNSGPHGDDFEPFVEMNWIHNSK-DFAVSMNGVKVEQDGASNLGEIKLG 334 LG R + G +P+++ + + V NG+ + E+ LG Sbjct: 818 LGLEVGKRIELAG----GRQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLG 873 Query: 335 VNGNLNPAASVWG 347 + L S++ Sbjct: 874 MAAALGRGHSLYA 886
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.008 Identities = 9/16 (56%), Positives = 11/16 (68%) Query: 55 VVGESGCGKSTFARAI 70 + GESG GK ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 256 bits (654), Expect = 1e-88 Identities = 238/239 (99%), Positives = 238/239 (99%) Query: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 121 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 PASPFENTAPAR TSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 341 bits (877), Expect = e-117 Identities = 125/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 6 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 65 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 66 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 125 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 126 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 185 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 186 IMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 245 I + +F Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 246 PLDDIIID---PFKRRPPEDAIAVSETTSLPTLPLD------------------LREFQM 284 + I + P E A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 285 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 325 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.030 Identities = 7/43 (16%), Positives = 17/43 (39%) Query: 30 SGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A A++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.8 bits (69), Expect = 1e-04 Identities = 12/31 (38%), Positives = 12/31 (38%) Query: 10 PVPEPIPGDPVPVPDPIPRPQPMPDPPPDEE 40 P P P PG P P P P PP E Sbjct: 575 PKPAPQPGPQPPQPPQPQPEAPAPQPPAGRE 605 Score = 26.6 bits (58), Expect = 0.005 Identities = 11/23 (47%), Positives = 11/23 (47%) Query: 19 PVPVPDPIPRPQPMPDPPPDEEP 41 P P P P P PQP P P E Sbjct: 573 PAPKPAPQPGPQPPQPPQPQPEA 595
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 582 bits (1501), Expect = 0.0 Identities = 312/388 (80%), Positives = 337/388 (86%), Gaps = 16/388 (4%) Query: 1 MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYFSDNSAKDGDQSYARLG 60 MK KVLAL+IPALLAAGAAHAAE+YNKDGNKLDLYGKVDGLHYFSD+S+KDGDQ+Y R+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQINDQLTGYGQWEYNIQANNTESSKNQSWTRLAFAGLKFADYGSFDYGRNYGVMY 120 FKGETQINDQLTGYGQWEYN+QAN TE SWTRLAFAGLKF DYGSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 121 DIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFFGLVNGLNFAVQYQGNNEGAS 180 D+EGWTDMLPEFGGDSYT ADN+MTGRANGVATYRNTDFFGLV+GLNFA+QYQG NE S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 181 N-----GQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAYTSSDRTNDQVNH--TAA 233 G NNG D+R++NGDG+G+STTYD+GMGFSAGAAYT+SDRTN+QVN T A Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240 Query: 234 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDS----DYAVANKTQNFEVTAQYQF 289 GGDKADAWTAGLKYDANNIYLATMYSETRNMTP+G + D VANKTQNFEVTAQYQF Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300 Query: 290 DFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATYYFNKNMSTYVDYKIN 349 DFGLRPAVSFLMSKG+DL N DDKDLVKYADVGATYYFNKN STYVDYKIN Sbjct: 301 DFGLRPAVSFLMSKGKDL-----TYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKIN 355 Query: 350 LLDEDDSFYAANGISTDDIVALGLVYQF 377 LLD+DD FY GISTDDIVALG+VYQF Sbjct: 356 LLDDDDPFYKDAGISTDDIVALGMVYQF 383
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 32.0 bits (72), Expect = 5e-04 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 16 LFTATLQAADVTITVNGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 L T+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPVETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 388 bits (999), Expect = e-130 Identities = 217/382 (56%), Positives = 294/382 (76%) Query: 1 MSGYTVKPPTGDTNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNTS 60 M+GY ++ G + +F DY+NL Y+KRG+ Q++++QQLG T + S S Q+YW TS Sbjct: 497 MNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTS 556 Query: 61 RSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRN 120 D+Q GLN F DI +L+YS + N WQ RD +LA +N+PFSHW+R+DS+S +R+ Sbjct: 557 NVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRH 616 Query: 121 SNASYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGA 180 ++ASYSMS+DL G MTNL+GVYGTLL DNNL+YSVQ G GG+ +SG++GY++LNYRG Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 181 YGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQTG 240 YGN N+GYS S D Q+YYG+SGG++AHA+G+T GQPL DT+VLVKAPGA + K+ENQTG Sbjct: 677 YGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTG 736 Query: 241 IHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIGG 300 + TDWRGYA+LP+ATEYRENRVAL+ N+LADNV+LD V V+PT GAI RA F A++G Sbjct: 737 VRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGI 796 Query: 301 KVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGQLQVSWGKDKNSNCI 360 K+LMTL + NK +PFGA+VT +++ IVA+NGQVYL+G+P +G++QV WG+++N++C+ Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 361 VEYKLPEVSPGTLLNQQTAICR 382 Y+LP S LL Q +A CR Sbjct: 857 ANYQLPPESQQQLLTQLSAECR 878
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 431 bits (1111), Expect = e-147 Identities = 223/358 (62%), Positives = 277/358 (77%), Gaps = 3/358 (0%) Query: 20 NKEHSAEKHVPDNSACTPLQDRLADASTEFDVGQQHLSLSVPQIYVGRMARGYVSPDLWE 79 N + ++ + AC PL + DA+ + DVGQQ L+L++PQ ++ ARGY+ P+LW+ Sbjct: 120 NTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWD 179 Query: 80 EGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSSN 139 GINAGLLNY+F+GNS N G S+YAYLNLQSG+NIG+WRLRDN+TWSYNS S+ Sbjct: 180 PGINAGLLNYNFSGNS---VQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSS 236 Query: 140 SSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHG 199 S NKWQHINT ERDIIPLRSRLT+GD YT GDIFD +NFRG ++ S + MLPDSQ G Sbjct: 237 SGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRG 296 Query: 200 FAPVIHGIARGTAQVSVKQNGYDVYQTTVPPGPFTIDDINSAANGGDLQVTIKEADGSIQ 259 FAPVIHGIARGTAQV++KQNGYD+Y +TVPPGPFTI+DI +A N GDLQVTIKEADGS Q Sbjct: 297 FAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQ 356 Query: 260 TLYVPYSSVPVLQRAGYTRYALAMGEYRSGNNLQSSPKFIQGSLMHGLEGNWTPYGGMQI 319 VPYSSVP+LQR G+TRY++ GEYRSGN Q P+F Q +L+HGL WT YGG Q+ Sbjct: 357 IFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQL 416 Query: 320 AEDYQAFNLGIGKDLGLFGAFSFDITQANTTLADGTRHSGQSVKSVYSKSFYQTGTNI 377 A+ Y+AFN GIGK++G GA S D+TQAN+TL D ++H GQSV+ +Y+KS ++GTNI Sbjct: 417 ADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNI 474
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 109 bits (273), Expect = 3e-31 Identities = 45/101 (44%), Positives = 61/101 (60%) Query: 15 QVLIMPRFARLTIALGLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYR 74 + + F RL +A A AE YFNPRFL++D DLS F G+E PPGTYR Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 75 VDIYLNDEFMTSRDITFIADDNNAELIPCLSTDLLVSLGIK 115 VDIYLN+ +M +RD+TF D+ ++PCL+ L S+G+ Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.5 bits (100), Expect = 2e-06 Identities = 42/239 (17%), Positives = 82/239 (34%), Gaps = 18/239 (7%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLI---GYAMTIALTIGVVFSLGF 63 R +L++ L +G G +P + L R S D+ G + + + + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLFFALINCAYSVFATVLKAWFAD 123 G L+D+F ++ +L+++ A + + + ++ + + + A A+ AD Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 124 NLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSINLPFWLAAICSAFPMLFIQIWVK 183 + + F G GP LG L+ S + PF+ AA + L + Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 184 RSEK---------IIATDTGSVWSPKVLLQDKALLWFTCSGFLASFVSGAFASCISQYV 233 S K + W + A L F+ V A+ + Sbjct: 183 ESHKGERRPLRREALNPLASFRW--ARGMTVVAALMAV--FFIMQLVGQVPAALWVIFG 237
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (249), Expect = 2e-27 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%) Query: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 58 I +TGA G GE + R QG + A E+L+++ L A+ DVR+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVL 118 AAI+E+ A + E IDILVN AG+ L H S E+WE N+ G+ +R+V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 178 M++R G I+ +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 227 T+ + ++G + +T++ + L P D+++AV + VS H+ Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 228 INTL 231 ++ L Sbjct: 248 MHNL 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.0 bits (114), Expect = 4e-08 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 16/118 (13%) Query: 44 VGAFIFGKMGDRIGRKKVLFITITMMGICTTLIGVLPTYAQIGVFAPILLVTLRIIQGLG 103 +G ++GK+ D++G K++L I + + + V ++ + + A R IQG G Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMA-------RFIQGAG 116 Query: 104 AGAEISGAGTMLAEYAPKGKR----GIISSFVAMGTNCGTLSATAI-----WAFMFFI 152 A A + ++A Y PK R G+I S VAMG G I W+++ I Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 224 bits (571), Expect = 6e-78 Identities = 83/151 (54%), Positives = 110/151 (72%), Gaps = 1/151 (0%) Query: 25 PKGVQPITNFDANRYLGKWYEIARLENWFERGLEQVSATYEKRNDGGIRVLNRGYDPTKN 84 P+ V+P+++F+ N YLGKWYE+ARL++ FERGL QV+A Y RNDGGI VLNRGY K Sbjct: 20 PESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLNRGYSEEKG 79 Query: 85 KWSESEGKAYFTGDTKTAALKVSFFGPFYGGYNVIKLDDE-YKYALVSGPNREYLWILAR 143 +W E+EGKAYF + LKVSFFGPFYG Y V +LD E Y YA VSGPN EYLW+L+R Sbjct: 80 EWKEAEGKAYFVNGSTDGYLKVSFFGPFYGSYVVFELDRENYSYAFVSGPNTEYLWLLSR 139 Query: 144 TQTIPDNVKADYVRTAQKLGFNVNELLWVKQ 174 T T+ + ++ +++ GF+ N L++V+Q Sbjct: 140 TPTVERGILDKFIEMSKERGFDTNRLIYVQQ 170
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 25.8 bits (56), Expect = 0.045 Identities = 19/72 (26%), Positives = 28/72 (38%), Gaps = 7/72 (9%) Query: 10 RWGAWAANNHEDVTWSSIAAGFKGLIPSKVRSRPQCCDDDAMIICECMARLKKNNSDLHD 69 +W WA N + FK IP K ++P D + + A + +H+ Sbjct: 195 QWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA----GHITMHN 250 Query: 70 LLVDYYVGGMTF 81 L VD GG T Sbjct: 251 LCVD---GGATL 259
>PF06872#EspG protein Length = 398 Score = 25.8 bits (56), Expect = 0.027 Identities = 10/20 (50%), Positives = 12/20 (60%) Query: 7 YYNSDNSPVLVCTHERYSHA 26 +Y S N P L+ TH R S A Sbjct: 291 FYQSFNVPALMLTHVRISQA 310
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 64.1 bits (156), Expect = 4e-18 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 23 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 68 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 40.3 bits (94), Expect = 1e-06 Identities = 22/112 (19%), Positives = 47/112 (41%), Gaps = 4/112 (3%) Query: 34 FEEPYEAFVELSDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQ-IIISP 92 F +PY E D+ ++ ++ + F+ + G +++ + + A + I ++ Sbjct: 42 FSKPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRS--NWNGYALIEDIAVAK 99 Query: 93 EYQGKGLATRAAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFSVEG 144 +Y+ KG+ T A+++ + L L N A H Y K F + Sbjct: 100 DYRKKGVGTALLHKAIEWAKEN-HFCGLMLETQDINISACHFYAKHHFIIGA 150
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 31.2 bits (71), Expect = 0.002 Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 74 SNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHR 133 +NK +L A +A T + ++A V A+ + ++ + GE+ + G +R R Sbjct: 2 ANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAK-----GEKVQLIGFGNFEVRER 56 Query: 134 P 134 Sbjct: 57 A 57
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 30.1 bits (67), Expect = 0.011 Identities = 18/81 (22%), Positives = 35/81 (43%), Gaps = 13/81 (16%) Query: 158 ETTSALHTYFNVGDIAKVSVSGLGDRFIDKVNDAKED-----------VLTDGIQTFPDR 206 E ++AL + N D K S S L + F ++V + + V ++ F + Sbjct: 57 EMSAALAQFRNRRDYEKKS-SNLSNSF-ERVLEDEALPKAKQILKLISVHGGALEDFLRQ 114 Query: 207 TDRVYLNPQDCSVINDEVLNR 227 ++ +P D ++ E+L R Sbjct: 115 ARSLFPDPSDLVLVLRELLRR 135
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.022 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 30.0 bits (67), Expect = 6e-04 Identities = 9/37 (24%), Positives = 17/37 (45%), Gaps = 5/37 (13%) Query: 4 LSWIIFGLIAGILAKWIMPG-----KDGGGFFMTILL 35 + I+ G I+G++ W+ K ++ ILL Sbjct: 163 AAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILL 199
>SECA#SecA protein signature. Length = 901 Score = 60.3 bits (146), Expect = 7e-13 Identities = 27/70 (38%), Positives = 31/70 (44%), Gaps = 5/70 (7%) Query: 155 RVEKMSPEAFEESVDAIRLAALDLH---AYWMAHPQEKAVQQPI--KAEEKPGRNDPCPC 209 +V+ PE EE R+ A L A E K GRNDPCPC Sbjct: 828 KVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPC 887 Query: 210 GSGKKFKQCC 219 GSGKK+KQC Sbjct: 888 GSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.1 bits (143), Expect = 9e-13 Identities = 18/84 (21%), Positives = 35/84 (41%) Query: 8 ASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAK 67 S +W A D+V+ D+ MP + +I ++ D+ +++++ K Sbjct: 33 TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIK 92 Query: 68 VMQAGAAGYLSKGAAPQEVVSAIR 91 + GA YL K E++ I Sbjct: 93 ASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 35/181 (19%), Positives = 61/181 (33%), Gaps = 37/181 (20%) Query: 290 ENILFLARADKNNVLVKLDSLS----------------LNKEVENLLDYL--EYLSDEKE 331 NI L D L SLS L E+ + YL + E Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239 Query: 332 ICFKVECNQQIFADKI---LLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNSYLNIDIAS 388 + F+ + N I ++ L+Q ++ N I + I P+ +I + D N + +++ + Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD-NGTVTLEVEN 298 Query: 389 PGTKINEPEKLFRRFWRGDNSRHSVGQGLGLSLVKA-IAELHGGSATYHYLNKHNVFRIT 447 G+ + K G GL V+ + L+G A K Sbjct: 299 TGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344 Query: 448 L 448 + Sbjct: 345 V 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 2e-20 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 2 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 61 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 117 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>INTIMIN#Intimin signature. Length = 939 Score = 704 bits (1818), Expect = 0.0 Identities = 220/790 (27%), Positives = 349/790 (44%), Gaps = 70/790 (8%) Query: 139 QQIASTSQQIGSLLAEDMNSEQAANMARGWASSQASGAMTDWLSRFGTARITLGVDEDFS 198 QQ AS Q+ S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224 Query: 199 LKNSQFDFLHPWYETPDNLFFSQHTLHRTDERTQINNGLGWRHFTPTWMSGINFFFDHDL 258 S DFL P+Y++ L F Q D R N G G R F P M G N F D D Sbjct: 225 --GSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDF 282 Query: 259 SRYHSRAGIGAEYWRDYLKLSSNGYLRLTNWRSAPELDNDYEARPANGWDVRAESWLPAW 318 S ++R GIG EYWRDY K S NGY R++ W + DY+ RPANG+D+R +LP++ Sbjct: 283 SGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRFNGYLPSY 341 Query: 319 PHLGGKLVYEQYYGDEVALFDKDDRQSNPHAITAGLNYTPFPLMTFSAEQRQGKQGENDT 378 P LG KL+YEQYYGD VALF+ D QSNP A T G+NYTP PL+T + R G END Sbjct: 342 PALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDL 401 Query: 379 RFAVDFTWQPGSAMQKQLDPNEVAARRSLAGSRYDLVDRNNNIVLEYRKKELVRLTLTDP 438 +++ F +Q +Q++P V R+L+GSRYDLV RNNNI+LEY+K++++ L + Sbjct: 402 LYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHD 461 Query: 439 VTGKSGEVKSLVSSLQTKYALKGYNVEATALEAAGGKVVTTG----KDILVTLPAYRFTS 494 + G + + +++KY L + +AL + GG++ +G +D LPAY Sbjct: 462 INGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAY---- 517 Query: 495 TPETDNTWPIEVTAEDAKGNLSNREQ-SMVVVQAPTLSQKDSSVSLSTQTLNADSHSTAT 553 N + + A D GN SN ++ V+ + + + +A + T Sbjct: 518 VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 554 LTFIAH------DAAGNPVVGLVLSTRHEGVQDITLSDWKDNGDGSYTQILTTGAMSGTL 607 +T+ A A PV ++S G ++ + NG G T L + + Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSANTNGSGKATVTLKSDKPGQVV 633 Query: 608 TLMPQLNGVDAAKAPAVVNIISVSSSRTHSSIKIDKDRYLSGNPIEVTVELR-DKNDKPV 666 A A AV I + + + IK DK ++ +T ++ K DKPV Sbjct: 634 VSAKTAEMTSALNANAV--IFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPV 691 Query: 667 KEQKQQLNNAVSIDNVKPGVTTDWKETADGVYKATYTAYTKGSGL-TAKLLMQNWNEDLH 725 Q+ + K +T+ K +G K T T+ T G L +A++ + Sbjct: 692 SNQEVTFTTTLG----KLSNSTE-KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAP 746 Query: 726 TAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNPINDHTVTFAVLSGS 785 F I + G L + + ++ Sbjct: 747 EVEFFTTLTIDDGNIEIVGTGVKGKLPTV---------------------WLQYGQVNLK 785 Query: 786 ATSFNNQNTAKTDVNGLATFDLKSSK---QEDNTVEVTLENGVKQTLIVSFVGDSSTAQV 842 A+ N + T ++ +A+ D S + +E T +++ + QT ++ + + + Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQT--ATYTIATPNSLI 843 Query: 843 DLQKSKNEVVADGNDSVTMTATVRDAKGNLLNDVMVTF----------NVNSAEAKLSQT 892 SK D ++ + N L +V + + + + + QT Sbjct: 844 VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQT 903 Query: 893 EVNSHDGIAT 902 ++ G+A+ Sbjct: 904 AQDAKSGVAS 913 Score = 199 bits (508), Expect = 6e-54 Identities = 93/375 (24%), Positives = 151/375 (40%), Gaps = 32/375 (8%) Query: 821 LENGVKQTLIVSFVGDSSTAQ--VDLQKSKNEVVADGNDSVTMTATVRDAKGNLLNDVMV 878 N V T+ V G D K ADG +++T TATV+ N V V Sbjct: 538 SSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQAN-VPV 596 Query: 879 TFNVNSAEAKLSQTEVNSH-DGIATATLTSLKNGDYRVTASVSSGSQANQQVNFIGDQST 937 +FN+ S A LS N++ G AT TL S K G V+A + + A I T Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQT 656 Query: 938 AALTLSVPSGDITVTNTAPQYMTATLQ-DKNGNPLKDKEITFSVPNDVASKFSISNGGKG 996 A + + T +T T++ K P+ ++E+TF+ + + Sbjct: 657 KASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFT------TTLGKLSNSTE 710 Query: 997 MTDSNGVAIASLTGTLAGTHMIMARLANSNVSDAQPMTFVADKDRAVVVLQTSKAEIIGN 1056 TD+NG A +LT T G ++ AR+++ V P + + + EI+G Sbjct: 711 KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV----EFFTTLTIDDGNIEIVGT 766 Query: 1057 GVDETTLTATVK-DPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQANGEAHVTLKGK 1115 GV T ++ N +G +T + N IA A+ VTLK K Sbjct: 767 GVKGKLPTVWLQYGQVNLKASGGNGKYT--------WRSANPAIASVDAS-SGQVTLKEK 817 Query: 1116 KAGTHTVTATLGNNNTSDSQPVTFVADKASAQVVLQISKDEITGNGVDSATLTATVKDQF 1175 GT T++ +SD+Q T+ ++ +V +SK + V++ Sbjct: 818 --GTTTISVI-----SSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSS 870 Query: 1176 DNEVNNLPVTFSSAS 1190 NE+ N+ + +A+ Sbjct: 871 QNELENVFKAWGAAN 885 Score = 86.3 bits (213), Expect = 1e-18 Identities = 91/396 (22%), Positives = 130/396 (32%), Gaps = 51/396 (12%) Query: 1117 AGTHTVTATLGNNNTSDSQPVTFVADKASAQVVLQIS--------KDEITGNGVDSATLT 1168 + + VTA + N + S V S V+ K +G ++ T T Sbjct: 522 SNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYT 581 Query: 1169 ATVKDQFDNEVNNLPVTFSSASSGLTLTPGVSNTNESGIAQATLAGVAFGEKTVTASLAN 1228 ATVK + N PV+F+ S L+ +NTN SG A TL G+ V+A A Sbjct: 582 ATVKKNGVAQANV-PVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAE 640 Query: 1229 NGASDNKTVHFIGDTAAAKIIELTPVPDSIIAGTPQNSSGSVITATV-VDNNGFPVKGVT 1287 ++ N D A I E+ + +A IT TV V PV Sbjct: 641 MTSALNANAVIFVDQTKASITEIKADKTTAVANGQ-----DAITYTVKVMKGDKPVSNQE 695 Query: 1288 VNFTSNAATAEMTNGGQAVTNEQGKATVTYTNTRSSIESGARPDTVEASLENGSSTLSTS 1347 V FT+ + T+ G A VT T+T G S +S Sbjct: 696 VTFTTTLGKLSNS---TEKTDTNGYAKVTLTSTTP-----------------GKSLVSAR 735 Query: 1348 I-NVNADASTAHLTLLQALFDTVSAGETTSLYIEVKDNYGNGVPQQ--EVTLSVSPSEGV 1404 + +V D + L T+ G + G GV + V L Sbjct: 736 VSDVAVDVKAPEVEFFTTL--TIDDGNIEIV--------GTGVKGKLPTVWLQYGQVNLK 785 Query: 1405 TPSNNAIYTTNHDGNFYASFTATKAGV---YQLTATLENGDSMQQTVTYVPNVANAEITL 1461 N YT AS A+ V + T T+ S QT TY N+ I Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVP 845 Query: 1462 AASKDPVIADNNDLTTLTATVADTEGNAIANTEVTF 1497 SK D + + N + N + Sbjct: 846 NMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAW 881 Score = 63.9 bits (155), Expect = 7e-12 Identities = 86/448 (19%), Positives = 154/448 (34%), Gaps = 44/448 (9%) Query: 1432 YQLTATLENGDSMQQTVTYVPNVANAEITLAASKDPVIADNNDLT-----------TLTA 1480 Y + + Q + P N TL+ S+ ++ NN++ + Sbjct: 403 YSMQFRYQFDKPWSQQIE--PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPH 460 Query: 1481 TVADTEGNA---IANTEVTFTLPEDVKANFTL-SDGGKVITDAEGKAK---VTLKGTKAG 1533 + TE + + + L V + L S GG++ A+ L G Sbjct: 461 DINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQG 520 Query: 1534 AH-----TVTASMTGGKS---EQLVVNFIADTLTAQ----VNLNVTEDNFIANNVGMTRL 1581 T A G S L + +++ + + + A+ Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580 Query: 1582 QATVTDGNGNPLANEAVTFTLPADVSASFTLGQGGSAITDINGKAEVTLSGTKSGTYPVT 1641 ATV NG AN V+F + VS + L SA T+ +GKA VTL K G V+ Sbjct: 581 TATVKK-NGVAQANVPVSFNI---VSGTAVLSAN-SANTNGSGKATVTLKSDKPGQVVVS 635 Query: 1642 VSVNNYGVSDTKQVTLIADAGTAKLASLTSVYSFVVSTTEGATMTASVTDANGNPVEGIK 1701 + + D A + + + + V+ + A PV + Sbjct: 636 AKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 1702 VNFRGTSVTLSSTSVETDDRGFAEILVTSTEVGLKTVSASLADKPTEVISRLLNASADVN 1761 V F T LS+++ +TD G+A++ +TST G VSA ++D +V + + + Sbjct: 696 VTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTL- 754 Query: 1762 SATITSLEIPEGQVMVAQDVAVKAHVNDQFGNPVAHQPVTFSAEPSSQMI----ISQNTV 1817 TI I V + Q + ++ ++ I S V Sbjct: 755 --TIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQV 812 Query: 1818 STNTQGVAEVTMTPERNGSYMVKASLPN 1845 + +G +++ N + + PN Sbjct: 813 TLKEKGTTTISVISSDNQTATYTIATPN 840 Score = 55.8 bits (134), Expect = 2e-09 Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 5/161 (3%) Query: 1878 TLTATLTSANGTPVEGQVINFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTAS 1937 T TAT+ NG ++F++ A LS TN SG+A V L S+K G V+A Sbjct: 579 TYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK 637 Query: 1938 FHNGVTIQTQTTVKVTGNSSTAHVASFIADPSTIAATNTDLSTLKATVEDGSGNLIEGLT 1997 + + + + A + AD +T A D T V G + Sbjct: 638 TAEMTS-ALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQE 695 Query: 1998 VYFALKSGSATLTSLTAVTDQNGIATTSVKGAMTGSVTVSA 2038 V F G + + T TD NG A ++ G VSA Sbjct: 696 VTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSA 734
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 38/259 (14%), Positives = 95/259 (36%), Gaps = 18/259 (6%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ I+ ++ A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL----LIMARFIQGAGAAA 119 Query: 139 VGGEWGGAALLSVESAPKNKK-AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWG 197 + + K S V +G GVG + + I Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------------H 167 Query: 198 WRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIA 257 W L ++ ++ ++ +++ + + + ++ +L + + Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 258 LRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRR 317 + + L +++ + + GL + + IG+L GG+ T+ F + + Sbjct: 228 VSVLSFL-IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV 286 Query: 318 VYITGTLIGTLSAFPFFMA 336 ++ IG++ FP M+ Sbjct: 287 HQLSTAEIGSVIIFPGTMS 305
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 27.5 bits (61), Expect = 0.012 Identities = 13/83 (15%), Positives = 33/83 (39%), Gaps = 6/83 (7%) Query: 16 RLFRRKNKLQREIQDVEKKIRDNQKRVLLLDNLSDYIKPGMSVEAIQGIIASMKGDYEDR 75 +++ NKL++ + +++ N++ + L ++ I + + I+ I E Sbjct: 385 SYYKKYNKLKKSEEAANEQLLQNEEELNYLYSVLTNINNADNYDEIEEIKK------ELI 438 Query: 76 VDDYIIKNAELSKERRDISKKLK 98 YI ++ SK + Sbjct: 439 ETGYIKFKKIYKSKKSKTSKPMH 461
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 28.6 bits (64), Expect = 0.041 Identities = 27/165 (16%), Positives = 56/165 (33%), Gaps = 23/165 (13%) Query: 40 VLMDYTTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDN 99 + MD +G+ LTA ++ S K++ V +D+ + + + + Sbjct: 43 IEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYS 102 Query: 100 PV---FVGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYA 156 PV + + +V +L I S N A L + G + + Sbjct: 103 PVSEKHLADGM---------TVGELCAAAITMSDNSAANLLLATVGG-----PAGLTAFL 148 Query: 157 EKLHLKDTH---FETVHGLDAPGQH---SSAYDLAVLSRAIIHGE 195 ++ T +ET PG ++ +A R ++ + Sbjct: 149 RQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQ 193
>PF01206#SirA family protein Length = 76 Score = 57.5 bits (139), Expect = 4e-15 Identities = 15/72 (20%), Positives = 35/72 (48%), Gaps = 1/72 (1%) Query: 4 KKLDVVTQVCPFPLIEAKAALAEMASGDELVIEFDCTQATEAIPQWAAEEGHAITDYQQI 63 + LD CP P+++AK LA M +G+ L + + + ++ + GH + + ++ Sbjct: 6 QSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEE 65 Query: 64 GDAAWSITVQKA 75 + +++A Sbjct: 66 DG-TYHFRLKRA 76
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 45.5 bits (108), Expect = 9e-08 Identities = 29/172 (16%), Positives = 65/172 (37%), Gaps = 29/172 (16%) Query: 1 MNILLFGKTGQVGWELQRALAPLGN-LIALDVHSTDY--------------------CGD 39 M L+ G G +G+ + + L G+ ++ +D + Y D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 40 FSNPEGVAETVKKIRPDVIVNAAAHTAVDKAESEPEF---AQLLNATSVEAIAKAANEVG 96 ++ EG+ + + + + AV + P + L ++ + + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK-IQ 119 Query: 97 AWVIHYSTDYVFPGTGEIPWQETDATA-PLNVYGETKLAGEKALQKHCAKHI 147 +++ S+ V+ ++P+ D+ P+++Y TK A E L H H+ Sbjct: 120 H-LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE--LMAHTYSHL 168
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 188 bits (479), Expect = 3e-59 Identities = 90/363 (24%), Positives = 149/363 (41%), Gaps = 54/363 (14%) Query: 1 MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLT--YAGNL-ESLAEISDSERYSFEHA 57 MK LVTG AGFIG V + ++ VV +D L Y +L ++ E+ + F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDAEAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSG 117 D+ D E M +FA + V V S+ P A+ ++N+ G +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCR----- 114 Query: 118 LDDEKKKNFRFHHI---STDEVYGDLPHPDEVNSNETLQLFTETTAYAPSSPYSASKASS 174 + + H+ S+ VYG N + T+ + P S Y+A+K ++ Sbjct: 115 -------HNKIQHLLYASSSSVYG---------LNRKMPFSTDDSVDHPVSLYAATKKAN 158 Query: 175 DHLVRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWL 234 + + + YGLP YGP+ P+ + LEGK++ +Y G RD+ Sbjct: 159 ELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT 218 Query: 235 YVED-------------HARALYTVVTEGKA-----GETYNIGGHNEKKNIDVVFTICDL 276 Y++D HA +TV T A YNIG + + +D + + D Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA 278 Query: 277 LDEIVPKEKSYREQITYVADRPGHDRRYAIDADKISRELGWKPQETFESGIRKTVEWYLA 336 L + +K+ +PG + D + +G+ P+ T + G++ V WY Sbjct: 279 LG--IEAKKNMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330 Query: 337 NTN 339 Sbjct: 331 FYK 333
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.4 bits (214), Expect = 2e-21 Identities = 66/344 (19%), Positives = 132/344 (38%), Gaps = 47/344 (13%) Query: 5 RVFIAGHRGMVGSAIRRQLEQRG-------------DVEL------VLRTRD----ELNL 41 + + G G +G + ++L + G DV L +L +++L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 42 LDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNK 101 D + D FAS ++V+++ + + + P + N+ NI+ N + Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 102 LLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSV 161 LL+ SS +Y K P + P + YA K A + +Y+ YG + Sbjct: 121 LLYASSSSVYGLNRKMPFSTD---DSVDHPVS-LYAATKKANELMAHTYSHLYGLPATGL 176 Query: 162 MPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAAS 221 +YGP P L +F +A + + V+ G R+F ++DD+A A Sbjct: 177 RFFTVYGPWGR--PD------MALFKFTKAMLEGKS-IDVYNYGKMKRDFTYIDDIAEAI 227 Query: 222 IHVMELAH----EVWLENTQPMLSH-----INVGTGVDCTIRELAQTIAKVVGYKGRVVF 272 I + ++ + +E P S N+G + + Q + +G + + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 273 DASKPDGTPRKLLDVTRLHQ-LGWYHEISLEAGLASTYQWFLEN 315 +P D L++ +G+ E +++ G+ + W+ + Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (262), Expect = 1e-27 Identities = 76/353 (21%), Positives = 122/353 (34%), Gaps = 42/353 (11%) Query: 6 LITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPH--------TCNPK 57 L+TG G G ++++ LLE G++V GI + N Y D P Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLND------YYDVSLKQARLELLAQPG 53 Query: 58 FHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAI 117 F H DL+D +T + + V+ V S E+P AD + G L +LE Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 118 RFLGLEKKTRFYQASTSELYGLVQEIPQKETTPF-YPRSPYAVAKLYAYWITVNYRESYG 176 R ++ AS+S +YGL +++P +P S YA K + Y YG Sbjct: 114 RHNKIQ---HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 177 MYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKM 236 + A F P K T+A+ G +Y RD+ + D + Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLE---GKSIDVY-NYGKMKRDFTYIDDIAEA 226 Query: 237 QWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAP 296 + D +G + E + DA Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIG------NSSPVELMDYIQAL-EDAL 279 Query: 297 GVKPGDVIIAVDPRY--FRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMV 347 G++ +P +V D +E +G+ PE T+++ V V Sbjct: 280 GIE-------AKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.9 bits (77), Expect = 7e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 A S + ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.4 bits (79), Expect = 8e-04 Identities = 53/268 (19%), Positives = 89/268 (33%), Gaps = 17/268 (6%) Query: 29 LSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQ 88 L S G A A+ ++G+++DRF ++ + ++ AGA + Y Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAI--- 89 Query: 89 TTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIG-WIASGLACGF 147 A F +L + T A T ++A A + D+ R R G + G+ G Sbjct: 90 MATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG- 147 Query: 148 LPQMLGY-ADISPTNIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILL 206 P + G SP + P A + L + FL K + + L A Sbjct: 148 -PVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRW 205 Query: 207 RDKN------FLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFML 260 VFF + +P A + IF G + + Sbjct: 206 ARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM 265 Query: 261 ALPFFTKRFGIKKVLLLGLVTAAIRYGF 288 R G ++ L+LG++ Y Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYIL 293 Score = 34.0 bits (78), Expect = 0.001 Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 20/153 (13%) Query: 253 FSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGV 312 + L + RFG + VLL+ L AA+ Y +L++G ++ G+ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGI 108 Query: 313 SYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMERMFAYQEPVN 372 + V D R G ++ C GFG + G LGG+M F+ P Sbjct: 109 TGATGAVAGAYIAD-ITDGDERARHFGFMS-ACFGFGMVAGPVLGGLMGG--FSPHAP-- 162 Query: 373 GLTFNWSGMWTFGAVMIAIIAVLFMIFFRESDN 405 + A + + + ES Sbjct: 163 ---------FFAAAALNGLNFLTGCFLLPESHK 186
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.6 bits (103), Expect = 5e-07 Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 18/195 (9%) Query: 1 MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAMI-VDLNTNKVIYSNHP 59 M R+ + SL + +P A A + S+ +++ MI +DL + + + + Sbjct: 1 MRYIRLCIISL--LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 60 DLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRV---RLNSEISRKDM 116 D P+ S K++ VL DE+L+ I + YS V L ++ ++ Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 117 LLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFV--EPTGLS-----V 169 A+ S+N +AA+L GG + A + +G N TR E Sbjct: 119 CAAAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETELNEALPGDA 173 Query: 170 HNVSTARDLTKLLIA 184 + +T + L Sbjct: 174 RDTTTPASMAATLRK 188
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.3 bits (63), Expect = 0.019 Identities = 5/33 (15%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 152 WLHNLDQHLKHW-VWLILVVVL-VVGVRWWLKR 182 L + ++ + W++L ++ + R L++ Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQ 247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (284), Expect = 1e-32 Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 12/253 (4%) Query: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLG 62 ++A IT + GIG+ A LA QG I ++ E+ K + AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKA-EARHAEAFPADVR 67 Query: 63 NLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIA 122 + ++ + +G ID+LVN AG + ++ +EW F+V+ G F S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 ARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNAVA 182 ++ M+ + + G I+ + S P +AY ++K A TK + LEL + I N V+ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGAIATPM-------NGMDDSDVKPDAEP---SIPLRRFGATHEIASLVVWLCSEGANYT 232 PG+ T M + +K E IPL++ +IA V++L S A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGQSLIVDGGFML 245 T +L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.2 bits (63), Expect = 0.044 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 5/127 (3%) Query: 122 GAKAMREAVPAHLPVSVKVRLGWDSGEK-KFEIADAVQQAGATELVVHGRTKEQGY-RAE 179 G EA+ ++ + +G + E+ K EI A E+ V GR +G R Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 180 HIDWQAIGD-IRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVK 238 ++ I + +++ L V A + + IS V+ G GAL + NL R++ Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL-LRNLDRLL- 307 Query: 239 YNEPRMP 245 E +P Sbjct: 308 MEETGIP 314
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 29.2 bits (65), Expect = 0.030 Identities = 11/35 (31%), Positives = 17/35 (48%), Gaps = 1/35 (2%) Query: 359 QRNTIKTQNYQ-TRDPQVFAAGDIVEGDKTVVYAV 392 + IK N+ DP F GD+ + D+ +V V Sbjct: 189 DKTAIKVSNFAYNLDPDSFKHGDVTQSDRQLVKTV 223
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.2 bits (68), Expect = 0.016 Identities = 19/124 (15%), Positives = 47/124 (37%), Gaps = 20/124 (16%) Query: 339 EMHNGKLTIVG-----RLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEF--- 390 E +G + G +++ + + ++++ + H +++ + + + ++ Sbjct: 19 ESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDAIKLVLDALVNSDYGVI 78 Query: 391 ---------GHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQ 441 GHR V EY SV +++ V + + L P + GIK Q Sbjct: 79 KDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDC-IELAPLHNPANI--EGIKACTQ 135 Query: 442 ALKE 445 + + Sbjct: 136 IMPD 139
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.8 bits (80), Expect = 6e-05 Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 12/79 (15%) Query: 1 MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTGDNRHIL 52 M+E D++H+ LS ++ L LR F + D + + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56 Query: 53 GWKNDELVAYARILKSDDD 71 G K++ ++ R +++ Sbjct: 57 GIKDNTVICSLRFIETKYP 75
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 28.6 bits (64), Expect = 0.018 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 3/56 (5%) Query: 68 MVTSFT---AVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEP 120 M+TSFT V + R A P Q L + F M+PVI ++Y +P Sbjct: 60 MMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQP 115
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 30.8 bits (69), Expect = 0.002 Identities = 34/173 (19%), Positives = 71/173 (41%), Gaps = 22/173 (12%) Query: 1 MKQIAFFIMLVSYATVVSSSPDITFHGNLIAPPTCIVSENKTIEIAFNEVIISDISGDNY 60 M +++ FI L+ + V + I GN+ PP C ++ + I + F + + DN Sbjct: 1 MIRLSLFISLLLTSVAVLADVQINIRGNVYIPP-CTINNGQNIVVDFGNINPEHV--DNS 57 Query: 61 KREVPYSVECDSENTDTGIQMKLTWTGVETDFNDSAVETDVVGLGVELQQ---------- 110 + EV ++ + +K+T + N+ + T++ G+ L Q Sbjct: 58 RGEVTKNISISCPYKSGSLWIKVTGNTMGVGQNN-VLATNITHFGIALYQGKGMSTPLTL 116 Query: 111 -----NGQRFQQGKAINISKTNLPKLHAVLVKKSGAVLSEGAFEAYATLQVDY 158 NG R G ++ +++ +V + +L+ G F A++ + Y Sbjct: 117 GNGSGNGYRVTAG--LDTARSTF-TFTSVPFRNGSGILNGGDFRTTASMSMIY 166
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 35.8 bits (82), Expect = 3e-05 Identities = 40/142 (28%), Positives = 65/142 (45%), Gaps = 21/142 (14%) Query: 41 PPCTVTGSDVDFGDVLIRRIDGS-QYLQPVTYKLDCGQRLTGADDLRMQLQGPTSVINGE 99 P CTV ++V++GD+ I+ + S + T ++C L M++ ++ G Sbjct: 37 PACTVQNAEVNWGDIEIQNLVQSGGNQKDFTVDMNCPYSLG-----TMKVTITSNGQTGN 91 Query: 100 TVL-----NTGIDGFGIRIQNATNDSL---ITVGSSAWLPFSI-----DNQPTLEA-VPV 145 ++L DG I + N+ N + +T+GS P I + TL A + Sbjct: 92 SILVPNTSTASGDGLLIYLYNSNNSGIGNAVTLGSQ-VTPGKITGTAPARKITLYAKLGY 150 Query: 146 KQNGVSLVSSAFSATATMVVDY 167 K N SL + FSATAT+V Y Sbjct: 151 KGNMQSLQAGTFSATATLVASY 172
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 749 bits (1936), Expect = 0.0 Identities = 218/885 (24%), Positives = 378/885 (42%), Gaps = 70/885 (7%) Query: 5 SLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKY 64 RL + +A + + + + ++ F+ RFL DL RF + + PG Y Sbjct: 19 RKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTY 78 Query: 65 NLQVQLNKQPLAEEHDIYWYAGEDDASKTYACLTPELVAQFGLKEDVAKNLQWSHDGKCL 124 + + LN +A D+ + D CLT +A GL + D C+ Sbjct: 79 RVDIYLNNGYMATR-DVTFNT-GDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACV 136 Query: 125 KPGQL-EGMEIKADLSQSALVISLPQAYLEYTWPDWDPPSRWDDGISGIIADYSITAQTR 183 + + D+ Q L +++PQA++ + PP WD GI+ + +Y+ + + Sbjct: 137 PLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV 196 Query: 184 HEENGGDDSNEISGNGTVGVNLGPWRVRADWQTDYQHTRSNDDDDEFSGDDTQKKWEWSR 243 GG+ S+ N G+N+G WR+R + Y + S+ + KW+ Sbjct: 197 QNRIGGN-SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGS--------KNKWQHIN 247 Query: 244 YYAWRALPSLKAKLALGEDYLNSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHT 303 + R + L+++L LG+ Y DIFDG N+ G +++DD MLP + RG+AP I G+A Sbjct: 248 TWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARG 307 Query: 304 TAKVTVSQMGRVIYETQVPAGPFRIQDL-GDSISGTLHVRIEEQNGQVQEYDISTASMPY 362 TA+VT+ Q G IY + VP GPF I D+ SG L V I+E +G Q + + +S+P Sbjct: 308 TAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPL 367 Query: 363 LTRPGQVRYKVMMGRPQEWGHHVEGGFFSGAEASWGIANGWSLYGGALGDKNYQSAALGI 422 L R G RY + G + E F + G+ GW++YGG Y++ GI Sbjct: 368 LQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGI 427 Query: 423 GRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYRFS 482 G+++ GA++ D+T +++ L D DG S R Y+K ++ + + GYR+S Sbjct: 428 GKNMGALGALSVDMTQANSTLPDD-----SQHDGQSVRFLYNKSLNESGTNIQLVGYRYS 482 Query: 483 EENFMTMSEYLDASDSEMVRTGND-------------------KEMYTATYNQNFRDAGV 523 + ++ + + D + T Q Sbjct: 483 TSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS- 541 Query: 524 SVYLNYTRHTYWD-REEQTNYNIMLSHYFNMGSIRNMSVSLTGYRYEYDNRADKGMYISL 582 ++YL+ + TYW + L+ F + ++S + + + D+ + +++ Sbjct: 542 TLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDIN---WTLSYSLTKNAWQKGRDQMLALNV 598 Query: 583 SMPWGD-----------NSTVSYNGNYGS-GTDSSQVGYFSRV--DDATHYQLNVGTSD- 627 ++P+ +++ SY+ ++ G ++ G + + D+ Y + G + Sbjct: 599 NIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGG 658 Query: 628 ----KHTSVDGYYSHDGSLAQVDLSANYHEGQYTSAGLSLQGGATLTAQGGALHRTQNMG 683 ++ ++ G ++ H + GG A G L Q + Sbjct: 659 GDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHANGVTLG--QPLN 715 Query: 684 GTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNNYYRNQAYIDLNKLPENAEATQS 743 T +L+ A G D VE N V T+ G AV+ Y N+ +D N L +N + + Sbjct: 716 DTVVLVKAPGAKDAKVE-NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNA 774 Query: 744 VVQATLTEGAIGYRKFAVISGQKAMAVLRLQDGSHPPFGAEVKNDNQQTVGLVDDDGNVY 803 V T GAI +F G K + L + PFGA V +++ Q+ G+V D+G VY Sbjct: 775 VANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVY 833 Query: 804 LAGVKPGEHMSVFW--SGVAHC--DINLPDPLPADLFNGLLLPCQ 844 L+G+ + V W AHC + LP L L C+ Sbjct: 834 LSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 407 bits (1048), Expect = e-148 Identities = 250/251 (99%), Positives = 250/251 (99%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGLYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 120 bits (303), Expect = 9e-32 Identities = 98/408 (24%), Positives = 169/408 (41%), Gaps = 25/408 (6%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIVVLTLCLTLLKGRE 197 E R A L V + GP +GG I W ++ LI + I V L L K Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR 194 Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWES 257 + ++ G+ L+ +G+ + ML F +S I +VSV+S + V Sbjct: 195 IKGH---FDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P ++++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLISPLIG-----RYGNKIDMRVLVTFSFLMYAVCYYWRSVTFMPTIDFTGIIMPQ 372 G M ++I IG R G + + VTF +V + S T F II+ Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL----SVSFLTASFLLETTSWFMTIIIVF 357 Query: 373 FFQGFAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 G + ++TI S L + S+ NF LS G ++ Sbjct: 358 VLGGLSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 6e-18 Identities = 62/412 (15%), Positives = 122/412 (29%), Gaps = 96/412 (23%) Query: 13 RRKYFSLLAVVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVTVVNHK 71 RR ++ F+ + + ++E + + + G + I + V + K Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 72 DTNYVRQGDILVSLDKTDATIALNKA---------------------------------- 97 + VR+GD+L+ L A K Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 98 ------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDY 136 K + Q + L + AE + + Y+ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 137 NRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKANKALVM 182 R+ L + I+K + S + + I + K LV Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 183 N-------TPLNR-QPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPG 233 L + + + + + I++PV+ + Q V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 QSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNA 292 ++LM +VP + V A + + + +GQ+ I + F G +G Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK--- 404 Query: 293 FSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 340 + + +V V +S++ L PL G+++TA I T Sbjct: 405 VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 2e-17 Identities = 30/105 (28%), Positives = 51/105 (48%) Query: 960 SILIADDHPTNRLLLKRQLNLLGYDVDEATDGVQALHKVSMQHYDLLITDVNMPNMDGFE 1019 +IL+ADD R +L + L+ GYDV ++ ++ DL++TDV MP+ + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1020 LTRKLREQNSSLPIWGLTANAQANEREKGLSCGMNLCLFKPLTLD 1064 L ++++ LP+ ++A K G L KP L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.8 bits (119), Expect = 4e-09 Identities = 33/116 (28%), Positives = 52/116 (44%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLDTLEQQFGLRFS-HAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + + +R S P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.5 bits (63), Expect = 0.020 Identities = 19/124 (15%), Positives = 40/124 (32%), Gaps = 6/124 (4%) Query: 34 QQGKNEEQRQHDEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEASA 93 Q + ++ + + + E+ Q Q K AT +KA+ + + Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET-EKTQEV 1122 Query: 94 DKKRDQSYEDELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANR 153 K Q + +S +Q Q + + V I + D Q + + Sbjct: 1123 PKVTSQVSPKQEQSETVQPQAEPARENDPTVN-----IKEPQSQTNTTADTEQPAKETSS 1177 Query: 154 NMTE 157 N+ + Sbjct: 1178 NVEQ 1181
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 114 bits (287), Expect = 5e-30 Identities = 81/371 (21%), Positives = 144/371 (38%), Gaps = 74/371 (19%) Query: 23 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 75 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 76 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 135 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 136 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 194 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG 254 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 --IPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 304 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 305 APLVKRTLLACRRALKDAGVE-ADEVLE--VVMVGGSTRVPLVRERVGEFFGRPPLTSID 361 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 362 PDKVVAIGAAI 372 P VA G Sbjct: 321 PLTCVARGGGK 331
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.032 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>PF07675#Cleaved Adhesin Length = 1358 Score = 26.2 bits (57), Expect = 0.014 Identities = 11/36 (30%), Positives = 14/36 (38%), Gaps = 1/36 (2%) Query: 31 INVDRVPEAAEALRAQG-FRQLPVVIAGDLSWSGFR 65 V PEA R QG + Q V + + FR Sbjct: 750 KTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFR 785
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 374 bits (961), Expect = e-127 Identities = 125/388 (32%), Positives = 196/388 (50%), Gaps = 33/388 (8%) Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLK 198 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRCLR 318 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 379 RQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 433 ++GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 434 FAFPEVTLPTPEVAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 476 + + ++ V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 477 HNWAACARMLETDVANLHRLAKRLGLKD 504 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.1 bits (62), Expect = 0.041 Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 7/93 (7%) Query: 3 TTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYRPNLLARNLSA 57 T++ E+AK AGV++ + + + +E P L Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 58 KSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 90 L VT + E++FH E Sbjct: 92 ILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.021 Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 206 ILGQTYLPRKFKTTVVIP---PQND--IDLHANDMNFVAIAENGKLVGFNLLVGGGLSIE 260 ++ +P+ T +P PQN + A+ ++VAI+++G L G + G++ Sbjct: 240 VMPYRAMPKT--NTYTLPASLPQNQASYSIQASAGSYVAISKDGVLYGTGVANASGVATV 297 Query: 261 HGNK-----KTYARTASEFGYLPLEHTLAVAE 287 + K Y + YLP+ + E Sbjct: 298 NMTKQITENGNYDVVITRSNYLPVIKQIQAGE 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.5 bits (79), Expect = 8e-04 Identities = 45/314 (14%), Positives = 112/314 (35%), Gaps = 36/314 (11%) Query: 69 LGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 127 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 128 GHTLLAEFSPRRHRGILLGAFSVVWT----VGYVLASIAGHHFISENPEAWRWLLASAAL 183 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 184 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLF-- 241 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 242 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 288 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 289 LNALLIVGALLGLV-------LTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLF 341 + ++ G + ++ L L L+ + + + L +S + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTII 354 Query: 342 VLFSTTISAVSNLV 355 ++F + + V Sbjct: 355 IVFVLGGLSFTKTV 368
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (263), Expect = 2e-29 Identities = 74/257 (28%), Positives = 117/257 (45%), Gaps = 11/257 (4%) Query: 11 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEK-QGVEVD 69 M+ ++GK A +TG G+G+A A LA GA+I + + E K + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 70 FMQVDITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 129 D+ A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 130 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 189 F S +K M+ ++SG I+ + S + + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 190 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGAAVFLA 240 + N ++PG TD+ +L N Q + IP + D+ A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 241 SPASNYVNGHLLVVDGG 257 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.018 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIA 107 G++++ + + G ++D+F R ++ ++ + +MAT P LWV+ +I Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>cloacin#Cloacin signature. Length = 551 Score = 33.1 bits (75), Expect = 0.001 Identities = 15/36 (41%), Positives = 20/36 (55%) Query: 253 ASGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASG 288 + G + S+N+ GGS SG GGG G GG +G Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Score = 30.8 bits (69), Expect = 0.006 Identities = 11/34 (32%), Positives = 14/34 (41%) Query: 254 SGRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGAS 287 SG H G G SGGG +GG ++ Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 30.1 bits (67), Expect = 0.012 Identities = 11/30 (36%), Positives = 11/30 (36%) Query: 259 HSDNSGSAGGSDSGGFSGGGGSSGGGGASG 288 GGS G G G S GG G G Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Score = 29.7 bits (66), Expect = 0.013 Identities = 12/34 (35%), Positives = 17/34 (50%), Gaps = 1/34 (2%) Query: 255 GRSYHSDNSGSAGGSDSGGFSGGGGSSGGGGASG 288 GR H+ + S G+ +GG +G G G SG Sbjct: 6 GRG-HNTGAHSTSGNINGGPTGLGVGGGASDGSG 38
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.038 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 9/132 (6%) Query: 211 GYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLA-----GEGN 265 P L N + A+ +E K YE+GK I+L + + ++ + + Sbjct: 147 RETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSS 206 Query: 266 KAFTSEEFTHFLEELTKQYPIVSIEDGLDESDW---DGFAYQTKVLG-DKIQLVGDDLFV 321 S++F LE K I I++ L E F+Y ++L D+F Sbjct: 207 DLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFE 266 Query: 322 TNTKILKEGIEK 333 K+ K G EK Sbjct: 267 YMNKLEKGGFEK 278
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 34.5 bits (79), Expect = 2e-04 Identities = 30/125 (24%), Positives = 54/125 (43%), Gaps = 10/125 (8%) Query: 137 ITNFLQLVATWSLLIILS--CGVGLIF----MVVGKTFPEMQKVL---PILLKPLYFISC 187 + L SLL L GL F MVV P + +++ P+ F+S Sbjct: 135 VAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSG 194 Query: 188 IMFPLHSIPKQYWSYLLWNPLVHVVELSREAVMPGYISE-GVSLNYLAMFTLITLFIGLA 246 +FP+ +P + + + PL H ++L R ++ + + + L ++ +I F+ A Sbjct: 195 AVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTA 254 Query: 247 LYRTR 251 L R R Sbjct: 255 LLRRR 259
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 28.7 bits (64), Expect = 0.010 Identities = 15/46 (32%), Positives = 22/46 (47%), Gaps = 2/46 (4%) Query: 1 MRRARAGFTLLEMLVAIAIFASLA-LMAQQVTNGVTRVNSAVAGHD 45 + R GFTLLE++V I I LA L+ + + + A D Sbjct: 4 TDKQR-GFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.8 bits (77), Expect = 7e-05 Identities = 13/24 (54%), Positives = 18/24 (75%) Query: 2 KRGFTLLEVMLALAIFALAATAVL 25 +RGFTLLE+ML L + ++A VL Sbjct: 3 QRGFTLLEMMLILLLMGVSAGMVL 26
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 74.6 bits (183), Expect = 2e-19 Identities = 39/170 (22%), Positives = 64/170 (37%), Gaps = 28/170 (16%) Query: 1 MPERGFTLLEIMLVIFLIGLASAGVVQTFATDSESPAKKAAQDFLTRFAQFKDRAVIEGQ 60 M +RGFTLLE+ML++ L+G+++ V+ F + A + F + + R + GQ Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQ 60 Query: 61 TLGVLIDPPGYQFMQRRQGQWLPVSATRLSAQVTVPKQVQMLLQPGSDIWQKEYALELQR 120 GV + P +QF+ + P D W L L+ Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPA-------------------PADDGWSGYRWLPLRA 101 Query: 121 RRL----TLHDIELEL-----QKEAKKKTPQIRFSPFEPATPFTLRFYSA 161 R+ ++ +L L + P + P TPF L A Sbjct: 102 GRVATSGSIAGGKLNLAFAQGEAWTPGDNPDVLIFPGGEMTPFRLTLGEA 151
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 217 bits (554), Expect = 3e-76 Identities = 90/146 (61%), Positives = 109/146 (74%), Gaps = 3/146 (2%) Query: 6 RTQKPRAGFTLLEVMVVIVILGVLASLVVPNLLGNKEKADRQKAISDIVALENALDMYRL 65 R + GFTLLE+MVVIVI+GVLASLVVPNL+GNKEKAD+QKA+SDIVALENALDMY+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 66 DNGRYPTTEQGLEALIQQPANMADSRNYRTGGYIKRLPKDPWGNDYQYLSPGEKGLFDVY 125 DN YPTT QGLE+L++ P + NY GYIKRLP DPWGNDY ++PGE G +D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 126 TLGADGQENGEGAGADIGNWNLQEFQ 151 + G DG+ E DI NW L + + Sbjct: 122 SAGPDGEMGTED---DITNWGLSKKK 144
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 452 bits (1164), Expect = e-160 Identities = 225/406 (55%), Positives = 300/406 (73%), Gaps = 1/406 (0%) Query: 1 MALFYYQALERNGRKTKGMIEADSARHARQLLRGKDLIPVHI-EARMNASAGGMLQRRRH 59 MA ++YQAL+ G+K +G EADSAR ARQLLR + L+P+ + E R + G Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 60 AHRRVAAADLALFTRQLATLVQAAMPLETCLQAVSEQSEKLHVKSLGMALRSRIQEGYTL 119 R++ +DLAL TRQLATLV A+MPLE L AV++QSEK H+ L A+RS++ EG++L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 120 SDSLREHPRVFDSLFCSMVAAGEKSGHLDVVLNRLADYTEQRQRLKSRLLQAMLYPLVLL 179 +D+++ P F+ L+C+MVAAGE SGHLD VLNRLADYTEQRQ+++SR+ QAM+YP VL Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 180 VVATGVVTILLTAVVPKIIEQFDHLGHALPASTRTLIAMSDALQASGVYWLAGLLGLLVL 239 VVA VV+ILL+ VVPK++EQF H+ ALP STR L+ MSDA++ G + L LL + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 GQRLLKNPAMRLRWDKTLLRLPVTGRVARGLNTARFSRTLSILTASSVPLLEGIQTAAAV 299 + +L+ R+ + + LL LP+ GR+ARGLNTAR++RTLSIL AS+VPLL+ ++ + V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 SANRYVEQQLLLAADRVREGSSLRAALAELRLFPPMMLYMIASGEQSGELETMLEQAAVN 359 +N Y +L LA D VREG SL AL + LFPPMM +MIASGE+SGEL++MLE+AA N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 QEREFDTQVGLALGLFEPALVVMMAGVVLFIVIAILEPMLQLNNMV 405 Q+REF +Q+ LALGLFEP LVV MA VVLFIV+AIL+P+LQLN ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 574 bits (1482), Expect = 0.0 Identities = 295/668 (44%), Positives = 431/668 (64%), Gaps = 34/668 (5%) Query: 24 LLPLVLAAALCSSPVWAEEATFTANFKDTDLKSFIETVGANLNKTIIMGPGVQGKVSIRT 83 L L++ AAL P AEE F+A+FK TD++ FI TV NLNKT+I+ P V+G +++R+ Sbjct: 11 SLTLLIFAALLFRPAAAEE--FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 84 MTPLNERQYYQLFLNLLEAQGYAVVPMENDVLKVVKSSAAKVEPLPLVGEGSDNYAGDEM 143 LNE QYYQ FL++L+ G+AV+ M N VLKVV+S AK +P+ + + GDE+ Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPG-IGDEV 127 Query: 144 VTKVVPVRNVSVRELAPILRQMIDSAGSGNVVNYDPSNVIMLTGRASVVERLTEVIQRVD 203 VT+VVP+ NV+ R+LAP+LRQ+ D+AG G+VV+Y+PSNV+++TGRA+V++RL +++RVD Sbjct: 128 VTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVD 187 Query: 204 HAGNRTEEVIPLDNASASEIARVLESLTKNSGENQ-PATLKSQIVADERTNSVIVSGDPA 262 +AG+R+ +PL ASA+++ +++ L K++ ++ P ++ + +VADERTN+V+VSG+P Sbjct: 188 NAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 263 TRDKMRRLIRRLDSEMERSGNSQVFYLKYSKAEDLVDVLKQVSGTLTAAKEEAEGTVGSG 322 +R ++ +I++LD + GN++V YLKY+KA DLV+VL +S T+ + K+ A+ + Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPV-AAL 306 Query: 323 REVVSIAASKHSNALIVTAPQDIMQSLQSVIEQLDIRRAQVHVEALIVEVAEGSNINFGV 382 + + I A +NALIVTA D+M L+ VI QLDIRR QV VEA+I EV + +N G+ Sbjct: 307 DKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGI 366 Query: 383 QWASKDAGLMQFANGTQIPIGTLGAAISQAKPQKGSTVISENGATTINPDTNGDLST-LA 441 QWA+K+AG+ QF N + +PI T A + +G +S+ LA Sbjct: 367 QWANKNAGMTQFTN-SGLPISTAIAG-------------------ANQYNKDGTVSSSLA 406 Query: 442 QLLSGFSGTAVGVVKGDWMALVQAVKNDSSSNVLSTPSITTLDNQEAFFMVGQDVPVLTG 501 LS F+G A G +G+W L+ A+ + + +++L+TPSI TLDN EA F VGQ+VPVLTG Sbjct: 407 SALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTG 466 Query: 502 STVGSNNSNPFNTVERKKVGIMLKVTPQINEGNAVQMVIEQEVSKVEGQTS-----LDVV 556 S S N FNTVERK VGI LKV PQINEG++V + IEQEVS V S L Sbjct: 467 SQTTSG-DNIFNTVERKTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT 525 Query: 557 FGERKLKTTVLANDGELIVLGGLMDDQAGESVAKVPLLGDIPLIGNLFKSTADKKEKRNL 616 F R + VL GE +V+GGL+D ++ KVPLLGDIP+IG LF+ST+ K KRNL Sbjct: 526 FNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNL 585 Query: 617 MVFIRPTILRDGMAADGVSQRKYNYMRAEQIYR--DEQGLSLMPHTAQPVLPAQNQALPP 674 M+FIRPT++RD S +Y Q + E +++ + P Q+ A Sbjct: 586 MLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENNDAMLNQDLLEIYPRQDTAAFR 645 Query: 675 EVRAFLNA 682 +V A ++A Sbjct: 646 QVSAAIDA 653
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 114 bits (286), Expect = 6e-32 Identities = 71/286 (24%), Positives = 115/286 (40%), Gaps = 38/286 (13%) Query: 40 IVRAMFWLMLLIISAKVAHSLWRYFSFSAEYTA-VSPSANKPPRADAKTFDKNDVQLISQ 98 I R +F+L++L+ ++A WR A VS P +A + ND L Sbjct: 14 IRRILFYLLMLLFCQQLAMIFWR---IGLPDNAPVSSVQITPAQARQQPVTLNDFTL--- 67 Query: 99 QNWFGKY-QPVAAPV-KQPEPVPVAETRLNVVLRGIAFG---ARPGAVIEEGGKQQVYLQ 153 FG + A + + + LN+ L G+ G +R A+I + +Q Sbjct: 68 ---FGVSPEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGV 124 Query: 154 GERLGSHNAVIEEINRDHVMLRYQGKIERLSLAEEERSTVAVTNKKAVSDEAKQAVAEPA 213 E + +NA I I D V+L+YQG+ E L L +E S SD A Sbjct: 125 NEEVPGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSG---------SDGVPGAQVNEQ 175 Query: 214 VSAPVEIPTAVRQALAKDPQKIFNYIQLTPVRKEG-IVGYAVKPGADRSLFDVSGFREGD 272 + + + +Y+ +P+ + + GY + PG F G ++ D Sbjct: 176 LQQ-------------RASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDND 222 Query: 273 IAIALNQQDFTDPRAMIALMRQLPSMDSIQLTVLRKGARHDISIAL 318 +A+ALN D D M ++ + + LTV R G R DI + Sbjct: 223 MAVALNGLDLRDAEQAKKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 278 bits (713), Expect = 3e-96 Identities = 111/274 (40%), Positives = 150/274 (54%), Gaps = 12/274 (4%) Query: 1 MLFDVFQQYPAAMPILATVGGLIIGSFLNVVIWRYPIML-RQQMAEFHGETPSTQSKI-- 57 +L ++ P L + L+IGSFLNVVI R PIML R+ AE+ + Sbjct: 3 LLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDE 62 Query: 58 ---SLALPRSHCPHCQQTIRVRDNIPLLSWLMLKGRCRDCQAKISKRYPLVELLTALAFL 114 +L +PRS CPHC I +NIPLLSWL L+GRCR CQA IS RYPLVELLTAL + Sbjct: 63 PPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSV 122 Query: 115 LASLVWPESGWGLAVMILSAWLIAASIIDLDNQWLPDVFTQGVLWTGLIAAWAQQSPLTL 174 ++ LA ++L+ L+A + IDLD LPD T +LW GL+ ++L Sbjct: 123 AVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNL-LGGFVSL 181 Query: 175 QDAVTGVLVGFITFYSLRWIAGIVLRKEALGMGDVLLFAALGGWVGALSLPNVALIASCC 234 DAV G + G++ +SL W ++ KE +G GD L AALG W+G +LP V L++S Sbjct: 182 GDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLV 241 Query: 235 GLIYAVI-----TKRGSTTLPFGPCLSLGGIATL 263 G + S +PFGP L++ G L Sbjct: 242 GAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIAL 275
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 46.9 bits (111), Expect = 2e-07 Identities = 18/58 (31%), Positives = 20/58 (34%) Query: 32 SSDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPTPDPEPEPEPEPVPTKT 89 S T + V+P P P EP PEP P PEP E E K Sbjct: 50 ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP 107 Score = 42.7 bits (100), Expect = 5e-06 Identities = 21/91 (23%), Positives = 33/91 (36%), Gaps = 2/91 (2%) Query: 33 SDTPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEP-TPEPTPDPEPEPEPEPVPTKTGY 91 +D P + PE +P P PEP PEP + +P P P+P+P+P + Sbjct: 58 ADLEPPQAVQ-PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 92 LTLGGSQRVTGATCNGETSDGFTFTPGEDVT 122 R N + + T + Sbjct: 117 DVKPVESRPASPFENTAPARPTSSTATAATS 147 Score = 42.3 bits (99), Expect = 6e-06 Identities = 21/104 (20%), Positives = 31/104 (29%), Gaps = 3/104 (2%) Query: 49 KPDPTPNPEPTPEPTPDPEPTPEPTPDPEPEPEPEPVPTKTGYLTLGGSQRVTGATCNGE 108 P PEP EP P+PEP PEP + E K + ++ E Sbjct: 63 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122 Query: 109 TSDGFTFTPGEDVT---CVAGNTTIATFNTQSEAARSLRAVEKV 149 + F A T + + R+L + Sbjct: 123 SRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Score = 40.0 bits (93), Expect = 4e-05 Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 5/60 (8%) Query: 35 TPPVDSGTGSLPEVKPDPTPNPEPTPEPTPDPEPTPEPTPDPEPE-----PEPEPVPTKT 89 P + +P +P PEP +PEP PEP P+P E +P+P P Sbjct: 45 APAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK 104 Score = 32.6 bits (74), Expect = 0.010 Identities = 15/40 (37%), Positives = 15/40 (37%) Query: 50 PDPTPNPEPTPEPTPDPEPTPEPTPDPEPEPEPEPVPTKT 89 P P T D EP P PEP EPEP P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI 83
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 639 bits (1651), Expect = 0.0 Identities = 223/842 (26%), Positives = 385/842 (45%), Gaps = 63/842 (7%) Query: 19 CSLSVIIIGCA-------SAYAVEFNKDLIEAEDRENVNLSQFETDGQLPVGKYSLSTLI 71 + + CA S+ + FN + + + +LS+FE +LP G Y + + Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 72 NNKRTPIHLDLQWVLIDN--QTAVCVTPEQLTLLGFTDEFIEKTQQNLIDGCYPIEK-EK 128 NN D+ + D+ C+T QL +G + D C P+ Sbjct: 85 NNGYMA-TRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIH 143 Query: 129 QITTYLDKGKMQLSISAPQAWLKYKDANWTPPELWNHGIAGAFLDYNLYASHYAPHQGDN 188 T LD G+ +L+++ PQA++ + + PPELW+ GI L+YN + G N Sbjct: 144 DATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGN 203 Query: 189 SQNISSYGQAGVNLGAWRLRTDYQYDQSFNNGKS-QATNLDFPRIYLFRPIPAMNAKLTI 247 S Q+G+N+GAWRLR + + + ++ S +L R I + ++LT+ Sbjct: 204 SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTL 263 Query: 248 GQYDTESSIFDSFHFSGISLKSDENMLPPDLRGYAPQITGVAQTNAKVTVSQNNRIIYQE 307 G T+ IFD +F G L SD+NMLP RG+AP I G+A+ A+VT+ QN IY Sbjct: 264 GDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNS 323 Query: 308 NVPPGPFAITNLFNT-LQGQLDVKVEEEDGRVTQWQVASNSIPYLTRKGQIRYTTAMGKP 366 VPPGPF I +++ G L V ++E DG + V +S+P L R+G RY+ G+ Sbjct: 324 TVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEY 383 Query: 367 TNVGGDSLQQPFFWTGEFSWGWLNNVSLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDV 426 + G ++P F+ G ++YGG+ L +R Y++ G+G N+ +LG+LS D+ Sbjct: 384 RS-GNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADR-YRAFNFGIGKNMGALGALSVDM 441 Query: 427 TRSDAQLHNQDKETGYSYRANYSKRFESTGSQLTFAGYRFSDKNFVTMNEYIND------ 480 T++++ L + + G S R Y+K +G+ + GYR+S + + Sbjct: 442 TQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYN 501 Query: 481 --------------TNHYTNYQNEKESYIVTFNQYLESLRLNTYVSLARNTYWDAS-SNV 525 T++Y N++ +T Q L Y+S + TYW S + Sbjct: 502 IETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDE 560 Query: 526 NYSLSLSRDFDIGPLKNVSTSLTFSRIN--WEEDNQDQLYLNISIPWGTSR--------- 574 + L+ F ++++ +L++S W++ L LN++IP+ Sbjct: 561 QFQAGLNTAF-----EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWR 615 Query: 575 --TLSYGMQRNQDNEISHTASWYDS--SDRNNSWSVSASGDNDEFKDMKASLRASYQHNT 630 + SY M + + +++ A Y + D N S+SV + ++ A+ + Sbjct: 616 HASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRG 675 Query: 631 ENGRLYLSGTSQRDSYYSLNASWNGSFTATRHGAAFHDYSGSADSRFMIDADGTEDIPLN 690 G + + D L +G A +G D+ ++ A G +D + Sbjct: 676 GYGNANIGYSHSDD-IKQLYYGVSGGVLAHANGVTLGQPLN--DTVVLVKAPGAKDAKVE 732 Query: 691 NKRAV-TNRYGIGVIPSVSSYITTSLSVDTRNLPENVDIENSVITTTLTEGAIGYAKLDT 749 N+ V T+ G V+P + Y +++DT L +NVD++N+V T GAI A+ Sbjct: 733 NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA 792 Query: 750 RKGYQIIGVIRLADGSHPPLGISVKDETSHKELGLVADGGFVYLNGIQDDNKLALRWGDK 809 R G +++ + + P G V E+S + G+VAD G VYL+G+ K+ ++WG++ Sbjct: 793 RVGIKLLMTLT-HNNKPLPFGAMVTSESS-QSSGIVADNGQVYLSGMPLAGKVQVKWGEE 850 Query: 810 SC 811 Sbjct: 851 EN 852
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 51.6 bits (123), Expect = 7e-09 Identities = 47/287 (16%), Positives = 92/287 (32%), Gaps = 16/287 (5%) Query: 197 PNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQ 256 N A+ + + E R A + + ++ E +QE+ + Sbjct: 999 TPNNIQAD-VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA---ENSKQESKTVEKN 1054 Query: 257 EQQVKTRTAEQNARIAAFEAERRREAE-QTRILAERQIQETEIDREQAVRSRKVEAEREV 315 EQ TA+ R A EA+ +A QT +A+ + E + + VE E + Sbjct: 1055 EQDATETTAQN--REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 316 RIKEIEQQQVTEIANQTKSIAIAAKSEQ---QSQAEARANLALAEAVSAQQNVETTRQTA 372 +++ + Q+V ++ +Q +++ Q + E + + E S T Q A Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172 Query: 373 EADRAKQVALIAAAQDAET------KAVELTVRAKAEKEAAEMQAAAIVELAEATRKKGL 426 + + + + T T +E + R Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232 Query: 427 AEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKSI 473 A + ND V + TS L A ++ K++ Sbjct: 1233 NVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAV 1279
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.0 bits (65), Expect = 0.028 Identities = 10/37 (27%), Positives = 20/37 (54%) Query: 347 GVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRL 383 G FD + GH+ + +L D++ VAV + + + + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPM 43
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 537 bits (1385), Expect = 0.0 Identities = 173/397 (43%), Positives = 254/397 (63%), Gaps = 11/397 (2%) Query: 7 VLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVN-GGEPAP--LAHHSYEGA 63 +LVINCGSSS+K+ ++++ D VL G+A+ I ++ L+ N GE ++ A Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDA 62 Query: 64 LKAIAFELEKRNLN-----DSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLH 118 +K + L + + +GHR+ HGG FT S +ITD+V+ I LAPLH Sbjct: 63 IKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLH 122 Query: 119 NYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTS 178 N AN+ GI++ Q+ P V VAVFDT+FHQTM AYLY +P++YY + +R+YGFHGTS Sbjct: 123 NPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGTS 182 Query: 179 HRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSG 238 H+YVSQRA +LN + ++ HLGNG+SI AV+NG+S+DTSMG TPLEGL MGTRSG Sbjct: 183 HKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSG 242 Query: 239 DVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLR-VLEKAWHEGHERAQLAI 297 +D +S++ + N S ++ ++NK+SG+ GISG+SSD R + + A+ G +RAQLA+ Sbjct: 243 SIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLAL 302 Query: 298 KTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRS 357 F +R+ + I +AA++ +D I+FT GIGEN IR +++ L LG ++D E N Sbjct: 303 NVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKVR 362 Query: 358 NSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGK 394 E I+S+ +++V V+PTNEE MIA D + + Sbjct: 363 GE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.4 bits (61), Expect = 0.047 Identities = 7/22 (31%), Positives = 13/22 (59%) Query: 4 VLITGSTGLVGGHLLRMLINEP 25 L+TG+ G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 73.4 bits (180), Expect = 2e-15 Identities = 69/313 (22%), Positives = 109/313 (34%), Gaps = 77/313 (24%) Query: 396 IMGHVDHGKTSLLDYI-----RSTKVASGEAG-------------GITQHIGAYHVETEN 437 ++ HVD GKT+L + + T++ S + G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 438 GMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAV 497 + +DTPGH F + R D +L+++A DGV QT + +P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 498 NKIDKPEADPDRV----KNELSQYGI-----------------LPEEWG----------- 525 NKID+ D V K +LS + E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 526 ---------------GESQFV---------HVSAKAGTGIDELLDAILLQAEVLELKAVR 561 ES H SAK GID L++ I + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 562 KGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVL-CGFEYGRVRAMRNELGQEVLEA 620 + G V + + R +A + + G LH D V E ++ M + E+ + Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 621 GPSIPVEILGLSG 633 + EI+ L Sbjct: 306 DKAYSGEIVILQN 318
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.1 bits (101), Expect = 2e-06 Identities = 41/203 (20%), Positives = 67/203 (33%), Gaps = 10/203 (4%) Query: 126 APSTSSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISST-PTQGQ 184 P+ +D + + ++A D+A PAP T S + S T Q Sbjct: 999 TPNNIQADVPSVPSNNEEIA--RVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 185 TPAATDGQQRVEVQGDLNNALTQPQN----QQQLNNVAVNSTLPTEPATVAPVRNGNASR 240 T Q R + +N Q Q +T E ATV + A Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE--KEEKAKV 1114 Query: 241 DTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAA 300 +T KTQ + + +Q+ E +PQA E P + A T+ PA Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQS-ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 301 TSAPAPKETATTAPVQTASPAQT 323 ++ ++ T + + Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVV 1196 Score = 43.1 bits (101), Expect = 2e-06 Identities = 38/199 (19%), Positives = 68/199 (34%), Gaps = 19/199 (9%) Query: 143 DLAGNATDQANGVQPAPGTTSAENTQQDVSL-----------------PPISSTPTQGQT 185 DL ++ N T+ N Q DV PP +TP++ Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 186 PAATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKT 245 A + +Q + T+ Q + S + T ++G+ +++T T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 246 QTAERPATTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSAPA 305 +T E + + + E + V ++ P + + +P A A P Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 306 PKETATTAPVQTASPAQTT 324 +T TTA T PA+ T Sbjct: 1159 QSQTNTTA--DTEQPAKET 1175
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 32.1 bits (73), Expect = 8e-04 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%) Query: 32 FYDSDQEIEKRTGADVGWVFDLEGEEGFRD----------REEKVINELTEKQGIVLATG 81 FYD + KR + GW+ + G+R E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 82 GGSVKSRETRNRLSARGVVVYLETTIEKQLA 112 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 287 bits (736), Expect = 1e-93 Identities = 80/301 (26%), Positives = 132/301 (43%), Gaps = 18/301 (5%) Query: 117 LENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDL 176 L + +I D + +A SA+ + D N +++RD+ + ++ + +D Sbjct: 219 LSDATIQQVTVDNQRIPQAAT-RASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDK 277 Query: 177 PVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNI 236 P ++E++ IV IN L ELGV W + + T G ++A+ G Sbjct: 278 PSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASN----GALG 333 Query: 237 GRINGRLLDL---ELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGAT 293 ++ R LD ++ LE + +++ P LL A I SE Y +G+ A Sbjct: 334 SLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDH-SETYYVKVTGKEVA- 391 Query: 294 SVEFKEAVLG--MEVTPTVLQKG---RIRLKLHISQNVPGQVLQQADGEVLAIDKQEIET 348 E K G + +TP VL +G I L LHI +G + I + ++T Sbjct: 392 --ELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEG-IPTISRTVVDT 448 Query: 349 QVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRL 408 V G++L +GGI+ + VPLLGDIP+ G LFR + R + I PR+ Sbjct: 449 VARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRI 508 Query: 409 V 409 + Sbjct: 509 I 509 Score = 34.9 bits (80), Expect = 6e-04 Identities = 27/139 (19%), Positives = 50/139 (35%), Gaps = 24/139 (17%) Query: 1 MKQWIAALLLMLIPGVQAA----KPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSG 56 K+ + LL+L A P + + +L +VVS ++ Sbjct: 9 FKRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIND 68 Query: 57 TVSLHLTDVPWKQALQTVVKSAGLITRQEDNILSVHSIAWQNNNIARQEAEQARAQANLP 116 VS + LQ + L+ + N+L + ++N+ +A Sbjct: 69 KVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYI----FKNSEVA-------------- 110 Query: 117 LENRSITLQYADAGELAKA 135 +R I LQ ++A EL +A Sbjct: 111 --SRLIRLQESEAAELKQA 127
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 4e-06 Identities = 21/92 (22%), Positives = 34/92 (36%), Gaps = 16/92 (17%) Query: 55 VACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMREMIE------MCD 108 + ++ + +G + I + + D + D R K GV +AL+ + IE C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVDRIELTVFVDNAPAIKVYKKYGFEIEG 140 L I N A Y K+ F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 31.6 bits (71), Expect = 0.007 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 275 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 331 R P+ G+ R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 332 YAYADRSEYLGDPDFVKVPWQA 353 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 28.4 bits (63), Expect = 0.017 Identities = 12/60 (20%), Positives = 22/60 (36%), Gaps = 4/60 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.003 Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 7/43 (16%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTEGDIWINDQRVTEMEPKD 75 +V+ G G GKSTL+ + GL+ + +D KD Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD-------FFSDTHFDIGTGKD 634
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.3 bits (91), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 52.0 bits (124), Expect = 5e-09 Identities = 38/182 (20%), Positives = 64/182 (35%), Gaps = 15/182 (8%) Query: 19 EQTPEKETEVQNEQPVVEEI---VQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVT 75 TP + TE E E Q+ + + Q E +A + +A T EV Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN---EVA 1086 Query: 76 EQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETV 135 + +E+++ Q + V +E V E+ + +VSP++ Q+E Sbjct: 1087 QSGSETKETQTTE--TKETATVEKEEKAKVETEKTQ---EVPKVTSQVSPKQEQSETVQP 1141 Query: 136 EIVEAAQEEAAKEEITDEELEAQALAAE---AAEEAVMVVPPAEEEQPVEEIAQEQEKPT 192 + E A+E I + + + A A E + V P E V E P Sbjct: 1142 Q-AEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 193 KE 194 Sbjct: 1201 NT 1202 Score = 48.1 bits (114), Expect = 7e-08 Identities = 44/210 (20%), Positives = 71/210 (33%), Gaps = 25/210 (11%) Query: 20 QTPEK-ETEVQNEQPVVEEIVQAQE----------PVKASEQAVEEQPQAHTEAE----- 63 TP + +V + EEI + E P + +E E Q E Sbjct: 998 TTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQD 1057 Query: 64 AETFAADVVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEV 123 A A EV ++ + KA + VAQ +ET + E V EE Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKET------QTTETKETATVEKEEK 1111 Query: 124 SPEEW--QAEAETVEIVEAAQEEAAKEEITDEELEAQALAAEAAEEA-VMVVPPAEEEQP 180 + E E V + ++E ++ E + +E A+ EQP Sbjct: 1112 AKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQP 1171 Query: 181 VEEIAQEQEKPTKEGFFARLKRSLLKTKEN 210 +E + E+P E S+++ EN Sbjct: 1172 AKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Score = 45.1 bits (106), Expect = 7e-07 Identities = 29/156 (18%), Positives = 46/156 (29%), Gaps = 14/156 (8%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASE------QAVEEQPQAHTEAEAETFAAD 70 Q +T E T + E+ VE + P S+ Q+ QPQA E + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 71 VVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQA 130 ++ ++ QP E + E V E+ V + PE+ P Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTES-TTVNTGNSVVENPENTTPATTQPTVNSE 1214 Query: 131 EAETVEI-------VEAAQEEAAKEEITDEELEAQA 159 + + E A D A Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALC 1250 Score = 44.7 bits (105), Expect = 9e-07 Identities = 36/177 (20%), Positives = 59/177 (33%), Gaps = 18/177 (10%) Query: 22 PEKETE---VQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVTEQV 78 PE E V +QA P S + A E TE V Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVD--EAPVPPPAPATPSETTETV 1040 Query: 79 AESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIV 138 AE+ K + + + + + + + + EV+ Q+ +ET E Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVA----QSGSETKETQ 1096 Query: 139 EAAQEEAAKEEITDEELEAQALAAEAAEEAVMV--VPP----AEEEQPVEEIAQEQE 189 +E A E +E +A+ + E + V P +E QP E A+E + Sbjct: 1097 TTETKETATVE---KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Score = 38.9 bits (90), Expect = 5e-05 Identities = 28/178 (15%), Positives = 56/178 (31%), Gaps = 6/178 (3%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAE-AETFAADVVEVT 75 +E E ++ V+ E+ Q+ K ++ ++ + E A+ EV Sbjct: 1065 NREVAKEAKSNVKAN-TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 76 EQVAESEKAQPEAEVV-AQPEPVVEETPEPVAIEREELPLPEDVNAEEVSPEEWQAEAET 134 + ++ Q ++E V Q EP E P E + + A+ P + + Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQS---QTNTTADTEQPAKETSSNVE 1180 Query: 135 VEIVEAAQEEAAKEEITDEELEAQALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPT 192 + E+ + + E A P + V + E T Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238
>PF01206#SirA family protein Length = 76 Score = 105 bits (265), Expect = 3e-34 Identities = 24/72 (33%), Positives = 41/72 (56%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRKG 80 + Y + +++ Sbjct: 65 EDGTYHFRLKRA 76
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.8 bits (132), Expect = 2e-10 Identities = 80/398 (20%), Positives = 147/398 (36%), Gaps = 32/398 (8%) Query: 13 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 70 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 71 PHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 129 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 130 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 187 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 188 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 240 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 241 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 296 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 297 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 355 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 356 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 389 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.018 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLTLKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 49.9 bits (119), Expect = 5e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPITPFEIMMAKI-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 367 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.045 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 84.5 bits (209), Expect = 4e-20 Identities = 72/408 (17%), Positives = 139/408 (34%), Gaps = 81/408 (19%) Query: 6 RHLAWWVVGLLAVAAIVAWWLLRPAGVP-EGFAVSNGRIEATEVDIASKIAGRIDTILVK 64 R +A++++G L +A I++ G +GR + I + I+VK Sbjct: 58 RLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKE----IKPIENSIVKEIIVK 113 Query: 65 EGQFVREGEVLAKMDTRV----------------LQEQRLEAI----------------- 91 EG+ VR+G+VL K+ L++ R + + Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 92 -------------------AQIKEAQSAVAAAQALLEQRQSETRAAQSLVNQRQAELDSV 132 Q Q+ + L+++++E + +N+ + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 133 AKRHTRSRSLAQRGAISAQQLDDDRAAAESARAALESAKAQVSASKAAIEAARTNIIQ-- 190 R SL + AI+ + + A L K+Q+ ++ I +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 191 -----------AQTRVEAAQATERRIAADID--DSELKAPRDGRV-QYRVAEPGEVLAAG 236 QT T + S ++AP +V Q +V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 237 GRVLNMVDLSDVY-MTFFLPTEQAGTLKLGGEARLILDAAPDLRIPATISFVASVAQFTP 295 ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVKNINL 410 Query: 296 KTVETSDERLKLMFRVKARIPPELLQQHLEYV--KTGLPGVAWVRVNE 341 +E D+RL L+F V I L + + +G+ A ++ Sbjct: 411 DAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 29.0 bits (65), Expect = 0.032 Identities = 23/98 (23%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 226 ENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFL--NEQRNAHPNQSLKNTL 283 E + RG GP +L + ++ + + + L T + N Q A N LK L Sbjct: 63 EAITLRERGWKGP-ILMLEGFFHAQD---LEIYDQHRLTTCVHSNWQLKALQNARLKAPL 118 Query: 284 AVHL------------PKRLVERLQQLGQIPDVSLKQL 309 ++L P R++ QQL + +V L Sbjct: 119 DIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTL 156
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 65.2 bits (159), Expect = 8e-19 Identities = 17/50 (34%), Positives = 32/50 (64%) Query: 1 MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE 50 +P+ + ++++C TLL FT++ R SLCE+ + E+AAF+A + + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 27.5 bits (61), Expect = 0.017 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 77 MTCLTVFIISVALLMVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKET 136 MT T II LL L + + GLA FL+ F V I P E Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAP-PNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 137 QVTQEE 142 +++ +E Sbjct: 120 KISMQE 125
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 64.5 bits (157), Expect = 2e-13 Identities = 56/314 (17%), Positives = 103/314 (32%), Gaps = 82/314 (26%) Query: 66 ITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVR------------YQARVD--RLQA--- 108 I P IV E+ K + ++KG+VL KL + QAR++ R Q Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 109 ------------------------DLMTATHNIK----TLRAQLTEAQANTTQVSAERDR 140 +++ T IK T + Q + + N + AER Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218 Query: 141 LFKNYQRY----------LKGSQAAVNPFS---------ERDIDDARQNF---LAQDALV 178 + RY L + ++ + E +A +Q + Sbjct: 219 VLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 179 KGSVAE----QAQIQSQLDSMVNGE----QSQIVSLRAQLTEAKYNLEQTVIRAPSNGYV 230 + + + + + + I L +L + + + +VIRAP + V Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338 Query: 231 TQVLIR-PGTYAAALPLRPVMVFIPEQKRQIV-AQFRQNSLLRLKPGDDAEVVFNALPGQ 288 Q+ + G +MV +PE V A + + + G +A + A P Sbjct: 339 QQLKVHTEGGVVT--TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYT 396 Query: 289 VFH---GKLTSILP 299 + GK+ +I Sbjct: 397 RYGYLVGKVKNINL 410
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 65.2 bits (159), Expect = 4e-15 Identities = 19/79 (24%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 1539 ESKLSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGV-SMVSANGRWVYKLQ 1597 +L G+A+ A++ L Q G + S G Y ++A+A+GV S ++ + Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGVA 61 Query: 1598 GSTNSQGEYSAALGAGIQW 1616 +T + G S G ++ Sbjct: 62 FNTYN-GGMSYGASVGYEF 79
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.020 Identities = 20/87 (22%), Positives = 30/87 (34%), Gaps = 13/87 (14%) Query: 8 MTVI---GAGSYGTALAITLARNGHEVVLWGHD---PEHIATLERDRCNAAFLPDVPFPD 61 M + AG G ++ L GH+VV G D + +L++ R P F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQF-- 56 Query: 62 TLHLESDLATALAASRNILVVVPSHVF 88 + DLA + VF Sbjct: 57 ---HKIDLADREGMTDLFASGHFERVF 80
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 235 bits (600), Expect = 1e-82 Identities = 87/153 (56%), Positives = 117/153 (76%), Gaps = 4/153 (2%) Query: 3 EQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRV 62 Q + QIQRIY KD+SFEAPN PH+FQ+DW+P++ DL T + Q+ DD+YEV L + Sbjct: 12 TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNI 71 Query: 63 TVTASLGEE--TAFLCEVQQGGIFSIAGIEGTQMAHCLGAYCPNILFPYARECITSMVSR 120 +V ++ AF+CEV+Q G+F+I+G+E QMAHCL + CPN+LFPYARE ++S+V+R Sbjct: 72 SVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNR 131 Query: 121 GTFPQLNLAPVNFDALFMNYL--QQQAGEGTEE 151 GTFP LNL+PVNFDALFM+YL Q+QA + TEE Sbjct: 132 GTFPALNLSPVNFDALFMDYLQRQEQAEQTTEE 164
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 247 bits (631), Expect = 2e-87 Identities = 77/154 (50%), Positives = 111/154 (72%) Query: 5 AIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKPMFTLEERVALAQQATAHLGN 64 AIYPG+FDPIT GH+DI+ R ++FD V +A+ +P+K+PMF+++ER+ +A AHL N Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPN 62 Query: 65 VEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQLAHMNRHLMPELESVFLMPSKEW 124 +V F L N+AR + A ++RGLR ++DFE E+Q+A+ N+ L +LE+VFL S E+ Sbjct: 63 AQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEY 122 Query: 125 SFISSSLVKEVARHQGDVTHFLPENVHQALMAKL 158 SF+SSSLVKEVAR G+V HF+P +V AL + Sbjct: 123 SFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQF 156
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 79.3 bits (195), Expect = 6e-17 Identities = 109/507 (21%), Positives = 185/507 (36%), Gaps = 86/507 (16%) Query: 651 ISDNAKWTGMTDIIQGTVILGNADSPVMLGSNQVIVEEQGKLSGFGGVAGNLSNSGIVDL 710 ++ A+WTG T + ++ + NA + VM ++ V G L L++ G VD Sbjct: 417 LASQARWTGATRAVD-SLSIDNA-TWVMTDNSNV-----GALR--------LASDGSVDF 461 Query: 711 TTYMP-GNILTVGGNYTGRNGLILLQTETGGDNSKTDRLVIKGNASGRTRVAVTQAGGTG 769 G + N +GL + D +D+LV+ +ASG+ R+ V +G Sbjct: 462 QQPAEAGRFKVLTVNTLAGSGLFRMNVFA--DLGLSDKLVVMQDASGQHRLWVRNSGS-E 518 Query: 770 AETLNGIEVIHVSGNADNAEFI---QTERITAGAYDYILKRGQGINSTNWYLISRKDIPV 826 + N + ++ + A F + ++ G Y Y L + W L+ K P Sbjct: 519 PASANTLLLVQTPLGS-AATFTLANKDGKVDIGTYRYRLAAN---GNGQWSLVGAKAPPA 574 Query: 827 PQPEAVPENHDNNLRPEAGSY-------VASIAAANNLFVTNLYERQGQELYISHMTGEE 879 P+P P ++AA N V L+ + Sbjct: 575 PKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALS 634 Query: 880 NEAGIWMYNKGKHNRWR---------DNSSQLRTRGNSYVVLIGGDIAQWSLNGTDRWHT 930 G N W DN + R +G D A ++ G RWH Sbjct: 635 KRLGELRLNPDAGGAWGRGFAQRQQLDNRAGRRFDQKVAGFELGADHA-VAVAGG-RWHL 692 Query: 931 GMMAGYGHNNNSTNALSTGYHSEGRMNGYTAGLYATWYANDETHNGSYLDSWLQYSWFDN 990 G +AGY + G+ + G YAT+ A+ +G YLD+ L+ S +N Sbjct: 693 GGLAGYTRGDRGFTGDGGGH-----TDSVHVGGYATYIAD----SGFYLDATLRASRLEN 743 Query: 991 HIN-----GERLPAESWKSKGFTVSLEAG--YSWKAGEFTDNYKGSHEWYVQPQLQVVRM 1043 G + + +++ G SLEAG ++ G W+++PQ ++ Sbjct: 744 DFKVAGSDGYAVKGK-YRTHGVGASLEAGRRFTHADG-----------WFLEPQAELAVF 791 Query: 1044 NVKSDKYHESNGTSIENTGNGNILTRLGARTWLTSKNGKNTRYA--VPFRPFVEAHWLHN 1101 Y +NG + + G ++L RLG GK A +P+++A L Sbjct: 792 RAGGGAYRAANGLRVRDEGGSSVLGRLGLEV------GKRIELAGGRQVQPYIKASVLQE 845 Query: 1102 SRVFGTSMNGVSIYQDGARDIGEINGG 1128 GT ++ +G E+ G Sbjct: 846 FDGAGT------VHTNGIAHRTELRGT 866
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 1e-05 Identities = 71/391 (18%), Positives = 129/391 (32%), Gaps = 33/391 (8%) Query: 20 LLVAFLTGIAGALQTPTLSIFLADELKARPIM--VGFFFTGSAIMGILVSQFLARHSDKQ 77 L L + L P L L D + + + G A+M + L SD+ Sbjct: 11 LSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF 70 Query: 78 GDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFASTANPQMFALAREHADRTG 137 G R ++L+ + + A ++L ++ A AD T Sbjct: 71 GRR-PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV----AGITGATGAVAGAYIADITD 125 Query: 138 RET-VMFSTFLRAQISLAWVIGPPLAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLP-- 194 + F+ A V GP L + GFS + AA + L LP Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 195 --SIQRNIPVVT-QPVEILPSTHRKRDTRLLFVVCSMMWAANNLYMINMPLFIIDELHLT 251 +R + P+ L V +M + +F D H Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 252 DKLAGEMI-GIAAGLEIPMMLIAGYYMKRIGKRLLMLIAIVSGMCFYASVLMATTPAVEL 310 G + + +I G R+G+R +++ +++ Y +L+A + Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY--ILLAFATRGWM 302 Query: 311 ELQILNAIFLGILCGIGMLYFQDLMPEKI---------GSATTLYANTSRVGWIIAGSVD 361 + L GIGM Q ++ ++ GS L + TS VG ++ ++ Sbjct: 303 ---AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Query: 362 GIMVEIWSYHALFWLAIGMLGIAMICLLFIK 392 + W+ W I + ++CL ++ Sbjct: 360 AASITTWNG----WAWIAGAALYLLCLPALR 386 Score = 32.1 bits (73), Expect = 0.004 Identities = 18/102 (17%), Positives = 34/102 (33%) Query: 17 AAFLLVAFLTGIAGALQTPTLSIFLADELKARPIMVGFFFTGSAIMGILVSQFLARHSDK 76 AA + V F+ + G + IF D +G I+ L + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 77 QGDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFA 118 + + ++L + L A+ ++ VLL+S Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG 314
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.9 bits (88), Expect = 5e-05 Identities = 33/208 (15%), Positives = 71/208 (34%), Gaps = 13/208 (6%) Query: 33 IIVEFLPVSLLTP----MAQDLGISEGVA---GQSVTVTAFVAMFASLFITQTIQATDRR 85 + ++ + + L+ P + +DL S V G + + A + + + RR Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 86 YVVILFAVLLTLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 145 V+++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 146 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMG----VLCIFWIIKSLPSLPGE 201 + +V LG +G F AAA + + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 202 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 229 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 9e-05 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG----------AEYTDAPA 71 V+R D +I N ILD + G + I +K IA +G P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/168 (16%), Positives = 61/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 9e-06 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 29 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 86 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 143 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLC 202 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 203 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 262 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 365 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 366 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 395 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 2e-05 Identities = 28/142 (19%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 365 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNN 424 LR ++L + + ++L L++ + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 425 IVKHA-----DASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQ-QGFGLTGMRERVTALG 478 +KH + L+G + + + L +E+ GS + + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 479 G---TLHISCLHG-TRVSVSLP 496 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 6e-12 Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 1/184 (0%) Query: 5 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYG 64 R+ +L+ L +L + + + ++ D+A D N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 65 PISDRVGRRPVILVGMSIFMLATLVA-VTTSSLTVLIAASAMQGMGTGVGGVMARTLPRD 123 +SD++G + ++L G+ I +++ V S ++LI A +QG G + + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 124 LYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWM 183 + A L+ + + + P IGG++ +W L ++ V F M Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLK 190 Query: 184 PETR 187 E R Sbjct: 191 KEVR 194
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.048 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.028 Identities = 20/101 (19%), Positives = 37/101 (36%), Gaps = 18/101 (17%) Query: 31 AAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQ--ANKRRSQILD 88 +EK +++ + A K+ + T + A++ ++ Q K + + Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 89 EAKAEAEQERTKIVA----------------QAQAEIEAER 113 E KA+ E E+T+ V Q QAE E Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 0.002 Identities = 33/150 (22%), Positives = 55/150 (36%), Gaps = 28/150 (18%) Query: 27 HAIRLCLLAALSGESVFLLGPPGIAKSLIARRL---------KFAFQNARAF-EYLMTRF 76 R+ + ++ + G G K L+AR L F N A L+ Sbjct: 148 EIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLI--- 204 Query: 77 STPEEVFG----PLSIQALKDEGRYERLTSGYLPEAEIVFLDEIWKAGPAILNTLLTAIN 132 E+FG + + GR+E+ G L FLDEI LL + Sbjct: 205 --ESELFGHEKGAFTGAQTRSTGRFEQAEGGTL------FLDEIGDMPMDAQTRLLRVLQ 256 Query: 133 ERQFR--NGAHVEKIPMRLLVAASNELPEA 160 + ++ G + +R +VAA+N+ + Sbjct: 257 QGEYTTVGGRTPIRSDVR-IVAATNKDLKQ 285
>PHPHLIPASEA1#Bacterial phospholipase A1 protein signature. Length = 289 Score = 496 bits (1278), Expect = 0.0 Identities = 287/289 (99%), Positives = 288/289 (99%) Query: 1 MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYL 60 MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYL Sbjct: 1 MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQEHDNPFTLYPYDTNYL 60 Query: 61 IYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQL 120 IYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQL Sbjct: 61 IYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGILGPNSVLGASYTQKSWWQL 120 Query: 121 SNSDESSPFRETNYEPQLFLGFATDYNFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYT 180 SNS+ESSPFRETNYEPQLFLGFATDY FAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYT Sbjct: 121 SNSEESSPFRETNYEPQLFLGFATDYRFAGWTLRDVEMGYNHDSNGRSDPTSRSWNRLYT 180 Query: 181 RLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGY 240 RLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGY Sbjct: 181 RLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLKIGYHLGDAVLSAKGQYNWNTGY 240 Query: 241 GGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF 289 GGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF Sbjct: 241 GGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQTRVGVGVMLNDLF 289
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.004 Identities = 11/71 (15%), Positives = 30/71 (42%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVTEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 601 bits (1551), Expect = 0.0 Identities = 206/478 (43%), Positives = 300/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNIQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTHLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL + S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 28.3 bits (63), Expect = 0.042 Identities = 34/190 (17%), Positives = 72/190 (37%), Gaps = 41/190 (21%) Query: 171 IIEQADRLRNLVDRL---LGPQLPGTRVTE-SIHKVAERV---VTLVSMELPDNVRLIRD 223 I+E + R ++ L + L + + S+ V + L S++ D ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 224 YDPSLPELAHDPDQIEQVLLN-IVRNALQ---ALGPEGGEIILRTRTAFQLTLHGERYRL 279 +P++ ++ Q+ +L+ +V N ++ A P+GG+I+L+ Sbjct: 246 INPAIMDV-----QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGT------KDNGTVT- 293 Query: 280 AARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGK---IEFTSWP 336 ++VE+ G + ++ TG GL R + G I+ + Sbjct: 294 ---LEVENTGSLALKNTKE------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 337 GHTEFSVYLP 346 G V +P Sbjct: 339 GKVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.026 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 15/161 (9%) Query: 227 NVFFVYAVYCGLTFFIPFLKNIYLLP----------VALVGAYGIINQYCLKMIGGPIGG 276 N+ F+ V CG F + ++P A +G+ I +I G IGG Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 277 MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAVFF 336 ++ D+ + P L + + + L E+ ++ + G + FT+ Sbjct: 315 ILVDR--RGPLYVLNIGVTFLSVSFLTASFLL-ETTSWFMTIIIVFVLGGLSFTK--TVI 369 Query: 337 APIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDL 377 + I + + + + GA M+L +F + ++ G +L + Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.4 bits (79), Expect = 9e-04 Identities = 31/160 (19%), Positives = 56/160 (35%), Gaps = 8/160 (5%) Query: 188 QLGYIFAATLFSLFGLLFMWICYSGVKERYVETQPANPAQKPGLLQSFRAIAGNRPLFIL 247 + AA +L GL F+ C+ + E +P + L SFR G + L Sbjct: 160 HAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLR-REALNPLASFRWARGMTVVAAL 215 Query: 248 CIANLCTLGAFNVKLAIQVYYTQYVLN-DPILLSYM--GFFSMGCIFIGVFLMPASVRRF 304 V A+ V + + + D + F + + + R Sbjct: 216 MAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLA-QAMITGPVAARL 274 Query: 305 GKKKVYIGGLLIWVLGDLLNYFFGGGSVSFVAFSCLAFFG 344 G+++ + G++ G +L F G ++F LA G Sbjct: 275 GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG 314
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.017 Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 3/36 (8%) Query: 49 TPKNILMIGPTGVGKTEIAR---RLAKLANAPFIKV 81 T +++ G +G GK +AR K N PF+ + Sbjct: 159 TDLTLMITGESGTGKELVARALHDYGKRRNGPFVAI 194
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 6e-06 Identities = 31/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARA 232 T E++ Q T T+Q V + + + A++Q + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.020 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 17 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 48 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.9 bits (67), Expect = 0.006 Identities = 6/21 (28%), Positives = 11/21 (52%) Query: 179 FGNLDDPNSEISQLLRQKPTY 199 GNL++P ++ L+ P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.013 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 89 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 90 TTVGWVSQFL 99 V F Sbjct: 656 ADAEAVKAFF 665
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.020 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.022 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWSWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 8e-05 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 391 PLDEKQLAALNTEIDNIVTLPELNNLS-----IIYQIKAVSALVKGKTDESYQAINTGID 445 ++ A+ + + T+ LN +S +Y + A + GK +++++ Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSL-AFNQYQSGKYEDAHKVFQALCV 64 Query: 446 LEMSWLNYVL-LGKVYEMKGMNREAADAYLTAFNLRP 481 L+ + L LG + G A +Y + Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 5e-08 Identities = 28/188 (14%), Positives = 51/188 (27%), Gaps = 13/188 (6%) Query: 3 REDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYDALRYLSQQIDV 62 R+ +L AL+L QG+++T+L +A+ + + DK + + I Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 63 WRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIAACTFYPDPGH----PIHQLA 118 + L + E + F+ + Q Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLEST--VTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 119 DQQKSAAYDFTHELLTT-------LEVDDPAMVAKQMELVLEGCLSRMLVNRSQADVDTA 171 +YD + L A M + G + L D+ Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 172 HRLAEDIL 179 R IL Sbjct: 191 ARDYVAIL 198
>SECA#SecA protein signature. Length = 901 Score = 32.2 bits (73), Expect = 0.005 Identities = 26/144 (18%), Positives = 54/144 (37%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.029 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 165 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 218 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 32.4 bits (74), Expect = 0.001 Identities = 22/122 (18%), Positives = 47/122 (38%), Gaps = 12/122 (9%) Query: 85 VNPSLINEVAEEIARLENLITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKA 144 + + I +V+ EI +L A E+ L +D E ++ A I F + V+ Sbjct: 29 IEKTSITDVSTEIEKLT---AALEKSKEELRAIKDQTEASMGADKAEI--FAAHLLVLDD 83 Query: 145 TEAMQRAQQAVTTSTVGASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDE 204 E + + + + A ++ ++ +D E+ AD RD+ + Sbjct: 84 PELVDGIKGKIENEQMNAEYALKEVSD-------MFVSMFESMDNEYMKERAADIRDVSK 136 Query: 205 KL 206 ++ Sbjct: 137 RV 138
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.9 bits (212), Expect = 3e-22 Identities = 69/249 (27%), Positives = 113/249 (45%), Gaps = 22/249 (8%) Query: 6 GKTVLILGGSRGIGAAIVRRFVTDGANVR-FTYAGSKD---AAEHLAQETGATAVFTDSA 61 GK I G ++GIG A+ R + GA++ Y K + A+ A A D Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 62 DRDAVIDVV----RKSGALDILVVNAGIGVFGDALELNADDIDRLFKINIHAPYHASVEA 117 D A+ ++ R+ G +DILV AG+ G L+ ++ + F +N ++AS Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 ARQMP--EGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQ 175 ++ M G I+ +GS N +P MAAYA+SK+A + L + I N+V Sbjct: 128 SKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 176 PGPIDTDA--------NPANGPMRDMLHGF---MAIKRHGQPEEVAGMVAWLAGPEASFV 224 PG +TD N A ++ L F + +K+ +P ++A V +L +A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 225 TGAMHTIDG 233 T +DG Sbjct: 247 TMHNLCVDG 255
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 49.6 bits (118), Expect = 1e-09 Identities = 20/100 (20%), Positives = 39/100 (39%), Gaps = 6/100 (6%) Query: 5 KQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGNKAGLF 64 ++++ + R + + A LF Q+G + S+ E+ G+ ++Y F +K+ LF Sbjct: 3 RKTKQEAQETR---QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 65 SRVLNEYVGTEAIPLADILRDDRPVGECLAEVLKEAARRY 104 S + L + P VL+E Sbjct: 60 SEIWELSESN-IGELELEYQAKFP--GDPLSVLREILIHV 96
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.2 bits (120), Expect = 6e-09 Identities = 49/310 (15%), Positives = 121/310 (39%), Gaps = 20/310 (6%) Query: 69 FFGAMADKYGRKPMMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGL-GMSGEYACASTY 127 GA++D++GR+P+++ ++ +V + A L++L + R + G+ G +G A A Y Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG--AVAGAY 119 Query: 128 AVESWPKNLQSKASAFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFI-----GLLPVLLV 182 + + +++ F+ + F G ++A ++ + FF GL + Sbjct: 120 IADITDGDERARHFGFMSACFGFG-MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 183 LWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPSY 242 + +S + + + + + FR + + F + + L Sbjct: 179 FLLPESHKGERR--PLRREALNPL-ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 243 LADNGVNTVVISTLMTIAGLG---TLTGTIFFGFVGDKIGVKKAFVVGLITSFIFLCPLF 299 ++ + + +++A G +L + G V ++G ++A ++G+I L Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA 295 Query: 300 FISVKNSSLIGLCLFGLM-FTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAA 358 F + + + L + ++ + + + +L+G L + + Sbjct: 296 FATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALT----SLTSIVG 351 Query: 359 PVLATYISGY 368 P+L T I Sbjct: 352 PLLFTAIYAA 361
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 64.2 bits (156), Expect = 6e-14 Identities = 44/240 (18%), Positives = 91/240 (37%), Gaps = 13/240 (5%) Query: 36 TPQRIVVLELSFADALAAVDVSPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAI 95 P RIV LE + L A+ + P G+AD + + + E VG R +P+LE + Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSE-PPLPDSVIDVGLRTEPNLELL 92 Query: 96 AALKPDLIIADSSRHAGVYIALQQIAPVLLLKSR--NETYAENLQSAAIIGEMVGKKREM 153 +KP ++ S+ + L +IAP + A +S + +++ + Sbjct: 93 TEMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAA 151 Query: 154 QARLEQHKERMAQWASQLPKGTR---VAFGTSREQQFNLHTQETWTGSVLASLGLNVPAA 210 + L Q+++ + + K + + + + +L G +P A Sbjct: 152 ETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYG--IPNA 209 Query: 211 MAGAS----MPSIGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASV 266 G + ++ +++L A +L + + PLWQ + + + V Sbjct: 210 WQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRV 269
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 32.9 bits (75), Expect = 0.004 Identities = 19/89 (21%), Positives = 29/89 (32%), Gaps = 9/89 (10%) Query: 546 GSFGTVQYSQIGKAVQSGNVEPEKARTWELGTRYDDGALTAEMGLFLINFNNQYDSNQTN 605 G F + NV EK + L + YD+ AL A + Q D+ Sbjct: 187 GFFVQYGGAYKRHHQVQENVNIEKYQIHRLVSGYDNDALYASV------AVQQQDAKLVE 240 Query: 606 DTVTARGKTRHTGLETQARYDLGTLTPTL 634 + T + Y G +TP + Sbjct: 241 E---NYSHNSQTEVAATLAYRFGNVTPRV 266
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.006 Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 10/77 (12%) Query: 85 LAVIPEYQGMGVGGRLIRTGIE--------HLRLMGCQTVFVLGHATYYPRHGFEPCAGD 136 +AV +Y+ GVG L+ IE L L Q + + +Y +H F A D Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLE-TQDINISA-CHFYAKHHFIIGAVD 152 Query: 137 KGYPAPYPIPEEHKACW 153 + +P E W Sbjct: 153 TMLYSNFPTANEIAIFW 169
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 1092 bits (2826), Expect = 0.0 Identities = 870/878 (99%), Positives = 874/878 (99%) Query: 1 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLVVACAFAAQAPLSSADLYFNPRFLADDPQA 60 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRL VACAFAAQAPLSSA+LYFNPRFLADDPQA Sbjct: 1 MSYLNLRLYQRNTQCLHIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQA 60 Query: 61 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN Sbjct: 61 VADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLN 120 Query: 121 TASVAGMNLLADDACVPLTTMVQDATAHLDVGQQRLNLTIPQAFMSNRARGYIPPELWDP 180 TASV+GMNLLADDACVPLT+M+ DATA LDVGQQRLNLTIPQAFMSNRARGYIPPELWDP Sbjct: 121 TASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDP 180 Query: 181 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDRSSGSK 240 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSD SSGSK Sbjct: 181 GINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSK 240 Query: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV Sbjct: 241 NKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPV 300 Query: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV Sbjct: 301 IHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTV 360 Query: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY Sbjct: 361 PYSSVPLLQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRY 420 Query: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR Sbjct: 421 RAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYR 480 Query: 481 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT 540 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT Sbjct: 481 YSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRT 540 Query: 541 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI Sbjct: 541 STLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNI 600 Query: 601 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD 660 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD Sbjct: 601 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD 660 Query: 661 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL 720 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL Sbjct: 661 GNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVL 720 Query: 721 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP 780 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP Sbjct: 721 VKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVP 780 Query: 781 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA 840 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA Sbjct: 781 TRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLA 840 Query: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR Sbjct: 841 GKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 33.1 bits (75), Expect = 4e-04 Identities = 30/158 (18%), Positives = 49/158 (31%), Gaps = 9/158 (5%) Query: 3 WCKRGYVLAAILALASATIQAADVTITVNGKVVAKPCTVSTTNATVDLGDLYSFSLMSAG 62 W R + A LA + +TI + VT VN + + + + G Sbjct: 258 WMGRLQYVGAYLAPSYSTINTSKVTGEVNFNHLTVGDHNAAQAGIIASNKTH------IG 311 Query: 63 AASAWHDVALELTNCPVG--TSRVTASFSGAADSTGYYKNQGTAQNIQLELQDDSGNTLN 120 W L + P G + S + Q ++QN + N+ Sbjct: 312 TLDLWQSAGLNIIAPPEGGYKDKPNDKPSNTTQNNAKNDKQESSQNNSNTQVINPPNSAQ 371 Query: 121 TGATKTVQVDDSSQSAHFPLQVRALTVNGGATQGTIQA 158 + QV D + V +N A GTI+ Sbjct: 372 KTEIQPTQVIDGPFAGGKNTVVNINRINTNA-DGTIRV 408
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.1 bits (62), Expect = 0.044 Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 1/79 (1%) Query: 211 SQNLGYYLSGTTADAGNSIFTNTASFSPAQGVGVQLTRNGTIIPANNTVSLGAVGTSAVS 270 S+N G ++ +A+ N FT PA V V L ++G ++ + + + Sbjct: 133 SENAGKEITIGSAN-PNVTFTEKTGDQPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYN 191 Query: 271 LGLTANYARTGGQVTAGNV 289 + TG VT G V Sbjct: 192 SNVNFYDVTTGATVTTGAV 210
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.008 Identities = 10/49 (20%), Positives = 25/49 (51%) Query: 230 LVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVAFV 278 + +I ++ I +W V +T W ++ FI + P+A + + ++ + Sbjct: 73 MGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSII 121
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.1 bits (81), Expect = 4e-04 Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 20/85 (23%) Query: 26 CDVLVANGKIIAVASNIPSDIVPNCT--------VVDLSGQILCPGFIDQHVHLIGGGGE 77 D+ + +G+I A+ D+ P T V+ G+I+ G +D H+H I Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFI----- 140 Query: 78 AGPTTRTPEVALSRLTEAGVTSVVG 102 + E AL +G+T ++G Sbjct: 141 ---CPQQIEEALM----SGLTCMLG 158
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 0.002 Identities = 66/317 (20%), Positives = 114/317 (35%), Gaps = 26/317 (8%) Query: 82 RPFLLASALASGLLILAMAWLPPFILVLLIRVLAGV-----ASAGMLIFGSTLIMQHTRH 136 RP LL S + + MA P ++ + R++AG+ A AG I T + RH Sbjct: 73 RPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARH 132 Query: 137 PFVLAALFSGVGIGIALGNEYVLAGLHFDLSSQTLWQGAGALSGMMLIALTLLMP-SKKH 195 ++A F G G+ G VL GL S + A AL+G+ + L+P S K Sbjct: 133 FGFMSACF---GFGMVAGP--VLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 196 AITPMPLAKTEQQIMSWW---------LLAILYGLAGFGYIIVATYLPLMAKDAGSPLLT 246 P+ W L+A+ + + G + A ++ T Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT 247 Query: 247 AHLWTLVGLSIVPGCFGWLWA---AKRWGALPCLTANLLVQAI-CVLLTLASDSPLLLII 302 + +L I+ + A R G L ++ +LL A+ + I Sbjct: 248 IGI-SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPI 306 Query: 303 SSLGFGGTFMGTTSLVMTIARQLSVPGNLNLLGFVTLIYGIGQILGPALTSMLSNGTSAL 362 L +G +L ++RQ+ L G + + + I+GP L + + + Sbjct: 307 MVL-LASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITT 365 Query: 363 ASATLCGAAALFIAALI 379 + A A + Sbjct: 366 WNGWAWIAGAALYLLCL 382
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 29.1 bits (65), Expect = 0.022 Identities = 10/45 (22%), Positives = 16/45 (35%) Query: 17 LFAIVAVCTFFVQSCARKSNHAASFQNYHATIDGKEIAGITNNIS 61 ++ + + +CA S Q IA IT NI+ Sbjct: 6 TLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIA 50
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 50.3 bits (120), Expect = 7e-09 Identities = 46/189 (24%), Positives = 76/189 (40%), Gaps = 5/189 (2%) Query: 7 RHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFNADVSLAPAAVSLYLAGGMALQW 66 RH L + L + + ++ P I N A + A L + G A+ Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV-- 68 Query: 67 LLGPLSDRIGRRPVLITGALIFTLACAATMFTTSMTQFLI-ARAIQGTSICFIATVGYVT 125 G LSD++G + +L+ G +I S LI AR IQG + V Sbjct: 69 -YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 126 VQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAALMHFMHWKVLFAIIAVMGFISFVGLL 185 V + K +I SIV + +GP G + H++HW L +I ++ I+ L+ Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL-LIPMITIITVPFLM 186 Query: 186 LAMPETVKR 194 + + V+ Sbjct: 187 KLLKKEVRI 195
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.9 bits (88), Expect = 3e-04 Identities = 21/133 (15%), Positives = 46/133 (34%), Gaps = 16/133 (12%) Query: 149 LKQQLEQQVREKAQSQAEVEAQQQKLVALNGYIAILEG-----KQQETEAQT-------- 195 +K+Q +K Q + ++ ++ + + + I E K + + + Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIA 250 Query: 196 QARLAALEAQLAEKNAELAKQTEQERKAYHKEITDQAIKRTLNLSEEESRFLIDAQLRKA 255 + + E + E EL + + + EI K L + + I +LR+ Sbjct: 251 KHAVLEQENKYVEAVNELR-VYKSQLEQIESEILS--AKEEYQLVTQLFKNEILDKLRQT 307 Query: 256 GWQADSKTLRFSK 268 TL +K Sbjct: 308 TDNIGLLTLELAK 320 Score = 31.7 bits (72), Expect = 0.017 Identities = 8/71 (11%), Positives = 27/71 (38%), Gaps = 3/71 (4%) Query: 144 QEVLTLKQQLEQQVREKAQSQAEVEAQQQKLVALNGYIAILEGKQQETEAQTQARLAALE 203 + + +L + Q ++E+ + +++ + + + + + QT + L Sbjct: 259 NKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT---QLFKNEILDKLRQTTDNIGLLT 315 Query: 204 AQLAEKNAELA 214 +LA+ Sbjct: 316 LELAKNEERQQ 326
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.4 bits (66), Expect = 0.029 Identities = 69/407 (16%), Positives = 120/407 (29%), Gaps = 45/407 (11%) Query: 40 LFVLFIFSFLDRINIGFAGL---TMGRDLGLS---ATMFGLATTLFYAAYVIFGIPSNIM 93 L V+ LD + IG + RDL S +G+ L+ + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 94 LSIVGARRWIATIMVLWGIASTATMFATGPT--SLYVLRILVGITEAGFLPGILLYLTFW 151 G R ++ L G A + AT P LY+ RI+ GIT A Y+ Sbjct: 67 SDRFGRR--PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG-AVAGAYIADI 123 Query: 152 FPAYFRARANALFMVAMPVTTALGSIVSGYILSLDGVMALKGWQWLFLLEGFPSVLLGVM 211 RAR G ++ G M F + L + Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGL-------MGGFSPHAPFFAAAALNGLNFLT 176 Query: 212 VWFWLDDSPDKAKWLTKEDKKCLQEMMDNDRLTLVQPEGAISHHAMQQRSMWREIFTPVV 271 F L +S + R + P + W T V Sbjct: 177 GCFLLPESHKGER--------------RPLRREALNPLASFR---------WARGMTVVA 213 Query: 272 MMYTLAYFCLTNTLSAISIWTPQILQSFNQGSSNITIGLLAAVPQICTILGMIYWSRHSD 331 + + + ++W F+ TIG+ A I L + Sbjct: 214 ALMAVFFIMQLVGQVPAALWVIFGEDRFHW--DATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 332 RRQERRHHTALPYLFAAAGWLLASATDHNMIQMLGIIMASTGSFSAMAIFWTTPDQSISL 391 R R L + G++L + + +++ ++G A+ Q Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEE 331 Query: 392 RARAIGIAVINATGNIGSALSPFMIGWLKDLT-GSFNSGLWFVAALL 437 R + ++ T ++ S + P + + + ++N W A L Sbjct: 332 RQGQLQGSLAALT-SLTSIVGPLLFTAIYAASITTWNGWAWIAGAAL 377
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 30.9 bits (70), Expect = 0.005 Identities = 32/182 (17%), Positives = 60/182 (32%), Gaps = 34/182 (18%) Query: 78 QIKQLLDVGTQT---LLVPMVQNADEAREAVRATRYPPAGIRGVGSALARASRWNRIPDY 134 Q++ LL T ++ PM+ +E R+A + + G ++ + Sbjct: 374 QLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVG----- 428 Query: 135 LQKANDQMCVLVQIETREAMKNLPQILDVEGVDGVFIGPADL----------SADMGYAG 184 + +E + VD IG DL + + Y Sbjct: 429 -----------IMVEIPSTAVAANLFA--KEVDFFSIGTNDLIQYTMAADRMNERVSYLY 475 Query: 185 NPQHPEVQAAIEQAIVQIREAGKAPGI---LIANELLAKRYLELGALFVAVGVDTTLLAR 241 P HP + ++ I GK G+ + +E+ L LG ++ + L AR Sbjct: 476 QPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPAR 535 Query: 242 AA 243 + Sbjct: 536 SQ 537
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.0 bits (122), Expect = 5e-09 Identities = 59/359 (16%), Positives = 110/359 (30%), Gaps = 33/359 (9%) Query: 67 TIREELGLS---ATEIGALLSVFSLAYGIAQLPCGPLLDRKGPRLMLGLGMFFWSLFQAM 123 + +L S G LL++++L G L DR G R +L + + ++ A+ Sbjct: 30 GLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAI 89 Query: 124 SGMVHNFTQFVLVRIGMGIGEAPMNPCGVKVINDWFNIKERGRPMGFFNAASTIGVAVSP 183 + RI GI A G I D + ER R GF +A G+ Sbjct: 90 MATAPFLWVLYIGRIVAGITGATGAVAG-AYIADITDGDERARHFGFMSACFGFGMVAG- 147 Query: 184 PILAAMMLVMGWRGMFITIGVLGIFLAIGWYMLYRNREHVELTAVEQAYLNAGSVNARRD 243 P+L +M F L + L E + + LN Sbjct: 148 PVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALN--------- 198 Query: 244 PLSFAEWRSLFRNRTMWGMMLGFSGINYTAWLYLAWLPGYLQTAYNLDLKSTGLMAAIPF 303 PL+ W + +M F + + A + + ++ D + G+ A Sbjct: 199 PLASFRWARGM--TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLA--- 253 Query: 304 LFGAAGMLVNGYVTDWLVKGGMAPIKSRKICIIAGMFCSAAFTLIVPQATTSMTAVLLIG 363 FG L +T + + + + + I+ T I Sbjct: 254 AFGILHSLAQAMITGPVAA------RLGERRALMLGMIADGTGYILLAFATRGWMAFPIM 307 Query: 364 MALFCIHFAGTSCWGLIHVAVASRMTASVG----SIQNFASFICASFAPIITGFIVDTT 418 + L + ++ V + ++ + S + P++ I + Sbjct: 308 VLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIV----GPLLFTAIYAAS 362
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 54.6 bits (131), Expect = 4e-12 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 62 DEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWLEVRASNAAAIALYESLGFN 121 A + +IAV DY+++G+G ALL I+ ++ L LE + N +A Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 122 EATIRRNYYPTTDG-REDAI 140 + Y E AI Sbjct: 148 IGAVDTMLYSNFPTANEIAI 167
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 216 bits (551), Expect = 8e-65 Identities = 107/460 (23%), Positives = 208/460 (45%), Gaps = 44/460 (9%) Query: 12 KRRTFAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQHAKSDWMEMEKQRGISIT 71 K +++H DAGKTT+TE +L AI G+V ++D +E+QRGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSV----DKGTTRTDNTLLERQRGITIQ 57 Query: 72 TSVMQFPYHDCLVNLLDTPGHEDFSEDTYRTLTAVDCCLMVIDAAKGVEDRTRKLMEVTR 131 T + F + + VN++DTPGH DF + YR+L+ +D +++I A GV+ +TR L R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 132 LRDTPILTFMNKLDRDIRDPMELLDEVENELKIGCAPITWPIGCGKLFKGVYHLYKDETY 191 P + F+NK+D++ D + +++ +L K + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVI------------------KQKVE 159 Query: 192 LYQSGKGHTIQEVRIVKGLNNPDLDAAVGEDLAQQLRDELELVKGASNEFDKELFLAGEI 251 LY + E + + +DL ++ L + + F + Sbjct: 160 LYPNMCVTNFTESEQWDTVIEGN------DDLLEKYMSGKSLEALELEQEESIRFHNCSL 213 Query: 252 TPVFFGTALGNFGVDHMLDGLVEWAPAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKH 311 PV+ G+A N G+D++++ + + + + G VFKI+ K Sbjct: 214 FPVYHGSAKNNIGIDNLIEVITNKFYSS---------THRGQSELCGKVFKIE--YSEK- 261 Query: 312 RDRVAFMRVVSGKYEKGMKLRQVRTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHG 371 R R+A++R+ SG +R K + I++ T + G+ +++AY G+I+ L N Sbjct: 262 RQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNEF 320 Query: 372 TIQIGDTFTQGEMMKFTGIPNFA-PELFRRIRLKDPLKQKQLLKGLVQLSEEG-AVQVFR 429 +++ +++ P L + P +++ LL L+++S+ ++ + Sbjct: 321 -LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379 Query: 430 PISNNDLIVGAVGVLQFDVVVARLKSEYNVEAVYESVNVA 469 + +++I+ +G +Q +V A L+ +Y+VE + V Sbjct: 380 DSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVI 419
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 27.0 bits (59), Expect = 0.003 Identities = 16/49 (32%), Positives = 20/49 (40%), Gaps = 8/49 (16%) Query: 4 WGIIFLVIALIA--------AALGFGGLAGTAAGAAKIVFVVGIILFLV 44 W +FL + A AL F LAGT G I V GI+ + Sbjct: 460 WKPLFLTLEKKAADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSYI 508
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 28.2 bits (63), Expect = 0.037 Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 10/69 (14%) Query: 187 FISGTGFAMDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 245 +G + D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 246 DVIVLGGGM 254 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.7 bits (124), Expect = 2e-09 Identities = 74/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%) Query: 5 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 61 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 62 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 121 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 122 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 181 G A G +S ++ P+ L FS F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 182 CDEAKGNLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 229 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 230 SGFSETAMTFIMMLVGLGM---VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCG 286 F A T + L G+ + M++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 287 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 340 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.0 bits (96), Expect = 2e-05 Identities = 27/204 (13%), Positives = 61/204 (29%), Gaps = 18/204 (8%) Query: 487 EARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 EA ++ Q + Q ++E + E + +E + L Sbjct: 133 EADTLKTQSSLLQARLEQ---TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT- 188 Query: 547 ATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQD 606 + ++ Q Q + E R + + + + LDD L Q Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 607 -------EHERQL-RLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLP 658 E E + +++ + Q+ +I+ +++ + QL L Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF------KNEILD 302 Query: 659 QEDEEESWLATRQQEAQSWQQRQN 682 + + + E ++RQ Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQ 326 Score = 35.6 bits (82), Expect = 0.001 Identities = 35/199 (17%), Positives = 72/199 (36%), Gaps = 13/199 (6%) Query: 671 QQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALH 730 + + Q + Q R Q L+ +E + E + +V + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTAL--------QASVFDDQQAFLAALMDEQTLTQL 782 Q T Q Q +L K +A+ T L + V + ++L+ +Q + + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 783 EQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLREN 842 L+Q EN+ +A + L Q + + + + E+ KLR+ Sbjct: 253 AVLEQ--ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL---DKLRQT 307 Query: 843 TTSQGEIRQQLKQDADNRQ 861 T + G + +L ++ + +Q Sbjct: 308 TDNIGLLTLELAKNEERQQ 326 Score = 33.3 bits (76), Expect = 0.005 Identities = 25/212 (11%), Positives = 65/212 (30%), Gaps = 19/212 (8%) Query: 375 QTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEV------ATALAQHAEQRPLRQHL 428 + Q L A + ++ ++ +++ Q+ + + + Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 429 VALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEA 488 + Q Q + Q ++ + E+ A +N + + +L D ++ ++A Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 489 --RIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 + LE + ++A + Y++ + L A E Sbjct: 249 IAKHAVLEQENKYVEAVN-----------ELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 547 ATLRGQLDAITKQLQRDENEAQSLRQDEQALT 578 + +L T + E + +QA Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASV 329
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.022 Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWLRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 293 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 352 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 353 KRGEIFG----LLGPNGAGKSTTFKMMCGL 378 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.3 bits (65), Expect = 0.047 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 34 YVTGLVGPDGAGKTTLMRMLAGL 56 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.2 bits (151), Expect = 6e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 82 ALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 141 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 142 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 196 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 197 AELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 254 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 255 QPGRKVLLYTDGRPDKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 308 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 309 ----DADDALRQGMPVTVQ 323 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.7 bits (178), Expect = 7e-18 Identities = 33/214 (15%), Positives = 77/214 (35%), Gaps = 17/214 (7%) Query: 9 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 67 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 68 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQL 127 IGE E + P + +RE+++ + + + + + F E + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120 Query: 128 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 187 A + + + + + +A L T + + G Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173 Query: 188 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 221 L W + + + ++ ++L+ Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.2 bits (102), Expect = 8e-07 Identities = 41/201 (20%), Positives = 64/201 (31%), Gaps = 34/201 (16%) Query: 16 AFLFLFAPTAFAAEQTVEAPSVDARAW----------ILMDYASGKVLAEGNADEKLDPA 65 + L A A P + I MD ASG+ L ADE+ Sbjct: 7 CIISLLATLPLAV-HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 66 SLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLN 125 S K++ V + A +L + + +P V D ++V +L Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGMTVGELC 119 Query: 126 KGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTT---FQTVHGLDAPGQF- 181 I S N A L V G + + +++G T ++T PG Sbjct: 120 AAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEALPGDAR 174 Query: 182 --STARDMA------LLGKAL 194 +T MA L + L Sbjct: 175 DTTTPASMAATLRKLLTSQRL 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 1e-05 Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 23/269 (8%) Query: 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130 +LG LSDR GRRPV+L + V + A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 131 QESFEEAVCIKITALMANVALIAPLLGPLVG---AAWIHVLPWEGMFVLFAALAAISFFG 187 + + + M+ + GP++G + P F AAL ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFLT 176 Query: 188 LQRAMPETATRIGEKLSLKELGRDYKLVLKNG-RFVAGALALGFVSLPLLAWIAQSP--I 244 +PE+ L + L G VA +A+ F ++ + Q P + Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAAL 232 Query: 245 IIITGEQLSSYEYGLLQVPIFGALIAGNL----LLARLTSRRTVRSLIIMGGWPIMIGLL 300 +I GE ++ + + + I +L + + +R R +++G G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 301 VAAAATVISSHAYLWMTAGLSIYAFGIGL 329 + A AT ++ + + + GIG+ Sbjct: 293 LLAFAT----RGWMAFPIMVLLASGGIGM 317
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 31 LVLLGPSGAGKSSLLRVL 48 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 30.3 bits (68), Expect = 0.008 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 9/54 (16%) Query: 2 RRVFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADD 55 R+V LV ALL AG A I K+G +LD Y ++ L HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.2 bits (185), Expect = 2e-17 Identities = 70/363 (19%), Positives = 123/363 (33%), Gaps = 65/363 (17%) Query: 1 MKVLVTGATSGLGRNAVEFLCQKGISVRA---------TGRNEAMGKLLEKMGAEFVPAD 51 MK LVTGA +G + + L + G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 104 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 105 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 164 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 165 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 222 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 223 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 268 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 269 MIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAW 328 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 329 LRD 331 RD Sbjct: 328 YRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.6 bits (134), Expect = 2e-10 Identities = 29/125 (23%), Positives = 51/125 (40%), Gaps = 17/125 (13%) Query: 4 RILVLGASGYIGQHLVRTLSRQGHQILA---------AARHVDRLAKLQLANVSCHKVDL 54 + LV GA+G+IG H+ + L GHQ++ + RL L HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 SWPDNLPALLQD--IDTVYFLVH------SMGEGGDFIAQERQVALNVRDALREVPVKQL 106 + + + L + V+ H S+ + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 107 IFLSS 111 ++ SS Sbjct: 122 LYASS 126
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 28.4 bits (63), Expect = 0.044 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 137 GVNGDAVDPKSVTSWADL------WKPEYKGSLLLTDDAREVFQMALRKLGYSGNTTDPK 190 G GD DP T+W D + ++ +L D + FQM + +GN T P Sbjct: 42 GFGGDPCDP--CTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPT 99 Query: 191 EIEAAYN 197 + A N Sbjct: 100 TLTAREN 106
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.017 Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 46 LTLLGPSGCGKTTVLRLIAGLE-TVDSGRIMLDNED 80 + L G G GK+T++ + GL+ D+ + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.046 Identities = 11/69 (15%), Positives = 22/69 (31%), Gaps = 20/69 (28%) Query: 389 NACKYCLE------FVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQ 442 N K+ + + + + + + + VE+ G + +E Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------------ST 311 Query: 443 GVGLAVARE 451 G GL RE Sbjct: 312 GTGLQNVRE 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 5e-22 Identities = 31/124 (25%), Positives = 62/124 (50%) Query: 2 RVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHLPDIAIVDLGLPDEDGLS 61 +LV +D+A +R L + AG+ V +A ++ D+ + D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSG 121 L+ R + LP+LV++A+ ++ ++ GA DY+ KPF + E++ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 LASQ 125 S+ Sbjct: 125 RPSK 128
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 143 bits (361), Expect = 3e-39 Identities = 62/206 (30%), Positives = 102/206 (49%), Gaps = 1/206 (0%) Query: 258 GKAFYYQPVLCTVQAKSTLTVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSG 317 KAF + ++ S V E ++L A++ + +L + + EAS D A IF+ Sbjct: 17 AKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAA 76 Query: 318 HHTLLDDPELLAAASELLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLH 377 H +LDDPEL+ +++E AEYA ++V ++ +D+EY++ R D+ D+ Sbjct: 77 HLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMKERAADIRDVSK 136 Query: 378 RTLVHLT-QTKEELPQFNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIAR 436 R L HL L T+++AE++ PS QL+ VKG G SHSA+++R Sbjct: 137 RVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSR 196 Query: 437 ELGIGWICQQGEKLYAIQPEETLTLD 462 L I + E IQ + + +D Sbjct: 197 SLEIPAVVGTKEVTEKIQHGDMVIVD 222
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 28.5 bits (63), Expect = 0.019 Identities = 10/47 (21%), Positives = 26/47 (55%) Query: 138 VESLRQSSEQNLSVPVALEAASSIAESAAQSTITMQARKGRASYLGE 184 E++ + ++N + +EA ++A +A + + A+ G+A+ G+ Sbjct: 293 REAVDRWIQENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGD 339
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 244 bits (625), Expect = 7e-76 Identities = 91/363 (25%), Positives = 155/363 (42%), Gaps = 33/363 (9%) Query: 308 QMRQLMTSQLGKVSHTFAHMPQDDPQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQA 367 + S+L S + + + + ++ +++ GE G GK L+++A Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 368 IHNESERAAGPYIAVNCELYGDAALAEEFIG---GDRTDNENGRLSRLELAHGGTLFLEK 424 +H+ +R GP++A+N + E G G T + R E A GGTLFL++ Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 425 IEYLAVELQSALLQVIKQGVITRLDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYA 484 I + ++ Q+ LL+V++QG T + R I DV+++A T DL + Q F LYY Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 485 LHAFEITIPPLRMRRGSIPALVNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELY 544 L+ + +PPLR R IP LV + ++ EK + D +AL + + WPGN EL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 545 SVIENLALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTS------------------- 585 +++ L I + L +E + + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 586 -----------LSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRKMKQHGIDAGQ 634 AE+E I+ A T G + + LLG+ R TL +K+++ G+ + Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYR 479 Query: 635 FKR 637 R Sbjct: 480 SSR 482
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 213 bits (543), Expect = 2e-59 Identities = 241/978 (24%), Positives = 397/978 (40%), Gaps = 113/978 (11%) Query: 14 RLAELKIRSPSIQLIKFGAIGLNAIIFPPLLIAADTGSQYGTNITINDGDRI---TGDTA 70 + A L+ + ++ L GA + I Q+G +I +D + +G T Sbjct: 10 KAAPLRRTTLAMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTI 69 Query: 71 DPSGNLYSVMTPAGNTPGNINLGNDVTVN---VNDASGYAKGIIIQGKNSSLTANRLTVD 127 SG + N + N + ++D + K L A+ T+ Sbjct: 70 KVSGRQAQGIL-LENPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATLA 128 Query: 128 VVGQT---SAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIGL 184 VG T I + + G+ A + ST++ G+ I + +T + I + G+ + Sbjct: 129 NVGDTWDDDGIALYVAGEQAQASIAD-STLQGAG-GVQIERGANVTVQRSAIVD-GGLHI 185 Query: 185 TINDYGTSVDLGSGSKITTDGS-TGVYIGGLNGNNANGAARFTATDLTID---VQGYSAM 240 DL + D + T V G + A++LT+D + G A Sbjct: 186 GALQSLQPEDLPPSRVVLRDTNVTAVPASGAPA----AVSVLGASELTLDGGHITGGRAA 241 Query: 241 GINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSANAL-------TVDVTGAAANGVEV 293 G+ + +VV L +TI+ A G G V A+ GV+V Sbjct: 242 GVAAMQGAVVHL-QRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDV 300 Query: 294 RGGTTTIGADSHISSAQGGGLVTSGSDAIINFTGTAAQRNSIFSGGSYGASAQTATAVVN 353 G + + A S + + + G + G A + +G + +G +T A Sbjct: 301 SGSSVEL-AQSIVEAPELGAAIRVGRGARVTVSGGSLS-------APHGNVIETGGARRF 352 Query: 354 M-QNTDITVD-RNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDLVI 411 Q +++ + G+ A G L L +TG A A+G T + + Sbjct: 353 APQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTSI-- 410 Query: 412 DMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLSDN 471 P +A+A+ + WTG++ Sbjct: 411 ---GPLDVALAS------------------------------------QARWTGAT--RA 429 Query: 472 VNGGKLDVAMNNSVWNVTSNSNLDTLAL-SHSTVDFASHGSTAGTFATLNVENLSGNSTF 530 V+ +D N+ W +T NSN+ L L S +VDF + AG F L V L+G+ F Sbjct: 430 VDSLSID----NATWVMTDNSNVGALRLASDGSVDFQQ-PAEAGRFKVLTVNTLAGSGLF 484 Query: 531 IMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAASF 590 M D L + ++G H L +RN GSE + N +L V AA+F Sbjct: 485 RMNV------FADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAATF 538 Query: 591 SASS---QVELGGYLYDVRKNG-TNWELYASGTVPEPTPNPEPTPAPAQPPIVNPD-PTP 645 + ++ +V++G Y Y + NG W L + P P P P+P P P QPP P+ P P Sbjct: 539 TLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAP 598 Query: 646 EPAPTPKPTTTADAGGNYLNVGYL--LNYVENRTLMQRMGDLRNQSKDGNIWLRSYG--G 701 +P + + A+A N VG L Y E+ L +R+G+LR G W R + Sbjct: 599 QPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQ 658 Query: 702 SLDSFASGKLSGFDMGYSGIQFGGDKRLSDVM-PLYVGLYIGSTHASPDYSG-GDGTARS 759 LD+ A + FD +G + G D ++ ++G G T ++G G G S Sbjct: 659 QLDNRAGRR---FDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDS 715 Query: 760 DYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNGVNANGTANGMSISLEAGQRFN 819 ++G YA+Y+A +GFY D ++ASR +N F V S V +G+ SLEAG+RF Sbjct: 716 VHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFT 775 Query: 820 LSPTGYGFYIEPQTQLTYSHQNEMTMKASNGLNIHLNHYESLLGRASMILGYDIT-AGNS 878 + G+++EPQ +L +A+NGL + S+LGR + +G I AG Sbjct: 776 HAD---GWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGR 832 Query: 879 QLNVYVKTGAIREFSGDTEYLLNNSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADYTQ 938 Q+ Y+K ++EF G N + +G G+G++A + H+ Y +Y++ Sbjct: 833 QVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSK 892 Query: 939 GNLFDQK-QVNGGYRFSF 955 G + GYR+S+ Sbjct: 893 GPKLAMPWTFHAGYRYSW 910
>INTIMIN#Intimin signature. Length = 939 Score = 258 bits (659), Expect = 4e-79 Identities = 120/378 (31%), Positives = 196/378 (51%), Gaps = 21/378 (5%) Query: 79 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 138 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 139 DRYLTWSQLGLTQQDDGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWG 198 ++ L + Q+G D +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 199 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDR 256 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 257 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 316 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 317 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 376 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 377 RSRYGIRQLIWQGDTQILS-----LTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVV 431 +S+YG+ +++W D+ + S G+Q SA+ + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 432 EDNQGQRVSSNEITLTLV 449 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.011 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 258 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 314 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 315 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 370 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 371 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATDTAAALGFIS 411 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 4e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 9e-14 Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 3e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 361 ELDKSLIERIIDPLT--HLVRNSLDHGIELPEKRLAAGKNSVGNLILSAEHQGGNICIEV 418 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 419 TDDGAGLNRERILAKAASQGLTVSENMSDDEVAMLIFAPGFSTAEQVTDVSGRGVGMDVV 478 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 479 KRNIQEMGG---HVEIQSKQGTGTTIRILLP 506 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.010 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 32/167 (19%), Positives = 65/167 (38%), Gaps = 11/167 (6%) Query: 126 ALAQAQGQLAKDKATLANARRDLARYQQLVKTNLVSRQELDAQQALVSETEGTIKADEAS 185 +A +L K+ L ++ ++ +L + L + T + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKE----EYQLVTQLFKNEILDKLRQTTDNIGLLT 315 Query: 186 --VASAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSGDTTGIVVITQTHPIDLLFTLPE 242 +A + + S I APV +V LK G +++ +T +V++ + +++ + Sbjct: 316 LELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALVQN 374 Query: 243 SDIATVVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSLDNQIDATTG 288 DI + Q A + VEA+ T L + ++LD D G Sbjct: 375 KDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Score = 43.3 bits (102), Expect = 1e-06 Identities = 25/144 (17%), Positives = 53/144 (36%), Gaps = 18/144 (12%) Query: 59 LAPVQAATA-VEQAVPRYLTGLGTITAA-NTVTVRSRVDGQLMALHFQEGQQVKAGDLLA 116 +A + + VE G +T + + ++ + + + +EG+ V+ GD+L Sbjct: 70 IAFILSVLGQVEIVAT----ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL 125 Query: 117 EIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLVKTNLVSRQELDAQQALVSETE 176 ++ A+ K +++L AR + RYQ L ++ EL+ L E Sbjct: 126 KLTAL-------GAEADTLKTQSSLLQARLEQTRYQILSRS-----IELNKLPELKLPDE 173 Query: 177 GTIKADEASVASAQLQLDWSRITA 200 + L + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFST 197
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 919 bits (2377), Expect = 0.0 Identities = 299/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVNDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+++ L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGFAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPELMEKLQQLP-QLSDVSS 709 D F+ P I + T + F L DAL+ +L+ Q P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 921 bits (2383), Expect = 0.0 Identities = 288/1035 (27%), Positives = 507/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQG------ALEDGTHRWQIQTNDELK 236 A+R+ L+ L ++ DV + N + G AL I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+AKL ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP ++VPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 ++ +A + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRDERS---ETAQQIIDRLRVKLAKEPGAN 641 + +V V GF+ G N+GM F++LKP +ER+ +A+ +I R +++L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 696 + + I G + ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 816 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGN 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 79.9 bits (197), Expect = 3e-17 Identities = 77/446 (17%), Positives = 162/446 (36%), Gaps = 26/446 (5%) Query: 592 VDNVTGFTGGS-RVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDI 650 +DN+ + S S + +T + + Q+ ++L++ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 651 RVGGRQSNASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQQDNGAE-- 703 V S+ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 704 MNLVYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 759 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 760 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 817 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 818 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 874 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 875 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRH 934 L +P +G L F + + + G++L IG++ +AI++V+ Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 935 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQ 994 L P+EA ++ ++ + +P+ GG + + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 995 LLTLYTTPVVYLFFDRLRLRFSRKPK 1020 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENK 508
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (310), Expect = 8e-33 Identities = 98/435 (22%), Positives = 190/435 (43%), Gaps = 25/435 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLL-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + L+ L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGLSPLTIAGLVAVGVVALVLYLLHARNNNRALFSLKL 257 G +L++VG+ L + L V V++ ++++ H R L Sbjct: 202 KGIILMSVGIVFFMLFTTSYSISFLI---------VSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYT--WLSMALIIAL 445 +Y+ L + II + Sbjct: 428 LYSNLLLLFSGIIVI 442
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.0 bits (70), Expect = 0.010 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 20/95 (21%) Query: 164 RQTSWLIVALATLLAALATFLLA------RGLLAPVKRLVDGTHKLAAGDFTTRVTPTSE 217 RQ + L+ A L AL L+A V+ V H LA + P S Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSF 131 Query: 218 DEL-----------GKLAQDFNQLASTLEKNQQMR 241 + L G L N+LA E+ QQMR Sbjct: 132 ERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 27.7 bits (61), Expect = 0.022 Identities = 48/178 (26%), Positives = 71/178 (39%), Gaps = 28/178 (15%) Query: 16 LLGLVLLAQGTATSAKNNLHFTGNLIDKSCTLVAPGGLLAEVRFPTISSRDLSTQMQSGK 75 +LG VL++Q A +NL F G LI +CT+ AEV + I ++L QSG Sbjct: 12 MLGAVLMSQ--HVHAADNLTFKGKLIIPACTVQN-----AEVNWGDIEIQNLV---QSGG 61 Query: 76 VSMAFELE-NCKGSSQSQNSVKVTFTGTEDTGQPGFLALDSDSQAQGV----------GI 124 F ++ NC S ++KVT T TG + S + G+ GI Sbjct: 62 NQKDFTVDMNC---PYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGI 118 Query: 125 GIETVDGVPVKINNNSGATFVLSDGSNTLLFNTWVQAKSGRDVTLGNFTATATATFEY 182 G G V +G + L+ + + + G F+ATAT Y Sbjct: 119 GNAVTLGSQVTPGKITGT----APARKITLYAKLGYKGNMQSLQAGTFSATATLVASY 172
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.9 bits (106), Expect = 3e-07 Identities = 32/165 (19%), Positives = 70/165 (42%), Gaps = 2/165 (1%) Query: 34 LDTIARNFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLIT 93 L IA +F+ +S ++ TA L ++ G L D +RL++ ++ G +I Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 94 ASSQSLA-MMILGTALTGLFSVVAQILVPLA-ATLASPDKRGKVVGTIMSGLLLGILLAR 151 S ++I+ + G + LV + A + RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLANLGGWRTVFWVASVLMALMALALWRGLPQMKSETHLNY 196 + G++A+ W + + + + + + +++ + H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.018 Identities = 23/94 (24%), Positives = 36/94 (38%), Gaps = 12/94 (12%) Query: 23 PYQEILLTRLCMHMQSKLLENRNKMLKAQGINETLFMALITLESQENHSIQPSELSCALG 82 P QE+ L + + L R A+G + + T + ++L ALG Sbjct: 756 PEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTI-------ADLVQALG 808 Query: 83 -----SSRTNATRIADELEKRGWIERRESDNDRR 111 SS ++ D L + GW RE+ RR Sbjct: 809 ADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRR 842
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.7 bits (194), Expect = 5e-18 Identities = 64/412 (15%), Positives = 120/412 (29%), Gaps = 97/412 (23%) Query: 25 LLLTLLFIIIAVAIGIYWFLVLRHFEETDDA----YVAGNQIQIMSQVSGSVTKVWADNT 80 L FI+ + I VL E A +G +I + V ++ Sbjct: 57 PRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEG 115 Query: 81 DFVKEGDVLVTLDPTDARQAFEKA------------------------------------ 104 + V++GDVL+ L A K Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPY 175 Query: 105 ----------------KTALASSVRQTHQLMINSKQLQANIEVQKIALAKA-------QS 141 K ++ Q +Q +N + +A + + +S Sbjct: 176 FQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKS 235 Query: 142 DYNRRVPLGNANLIGREELQHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQ 201 + L + I + + + A +L V Q ++ IL K E Q Q Sbjct: 236 RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQL 295 Query: 202 AATEVRN------------------AWLALERTRIVSPMTGYVSRRAVQ-PGAQISPTTP 242 E+ + + + I +P++ V + V G ++ Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 243 LMAVVPA-TNMWVDANFKETQIANMRIGQPVTITTDIYGDDVKY---TGKVVGLDMGTGS 298 LM +VP + V A + I + +GQ I + + +Y GKV + + Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNI-----N 409 Query: 299 AFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYPLRIGLSTLVSVNTTNR 350 ++ G V+ + + PL G++ + T R Sbjct: 410 LDAIE--DQRLGLVFNVIISIEENCLST--GNKNIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 132 bits (333), Expect = 9e-36 Identities = 97/405 (23%), Positives = 169/405 (41%), Gaps = 23/405 (5%) Query: 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRV 76 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVKLFLWSTIAFAIASWACGVS-SSLNMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAK 135 G +L L+ I S V S ++LI R IQG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETR 195 R A L V + GP +GG I+ HW + + +P+ + + L L +E R Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVR 194 Query: 196 TERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTD 255 + D G+ L+ +GI + ML F++ I +V+V++ + Sbjct: 195 I-KGHFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 256 DNPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGI 315 +P VD L K+ F IG LC + + G + ++P ++++V+ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 316 IPVILS-PIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGF- 373 + VI+ I G + ++ +V F ++ S + I F Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFMTIIIVFV 358 Query: 374 --AVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSI 416 ++ ++TI S L + A SL NFT L+ G +I Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 292 bits (750), Expect = e-105 Identities = 131/170 (77%), Positives = 148/170 (87%) Query: 2 PLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPNKEVMPERGIHTLEHLFA 61 PLLDSFTVDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ E+GIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMEDVLKVQDQNQIP 121 GFMRNHLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VADAW AAMEDVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA++ILE V +N N+ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 777 bits (2009), Expect = 0.0 Identities = 319/849 (37%), Positives = 470/849 (55%), Gaps = 48/849 (5%) Query: 31 SGMLCTTANAEEYYFDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQK 90 + ++ E YF+P L DLSRF PGTY+VDI+LN ++ + Sbjct: 35 AFAAQAPLSSAELYFNPRFLAD--DPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATR 92 Query: 91 KITFTAN-AEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDF 149 +TF +EQ + P T QL +G+ + + DD+ + L +I A+ D Sbjct: 93 DVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVP-LTSMIHDATAQLDV 151 Query: 150 NHQRLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNM 209 QRLNL+IPQ + ARGY+ P WD GI NY+F+G+ + R G S YLN+ Sbjct: 152 GQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNL 211 Query: 210 QNGANFGPWRLRNYSTWTRNDQTSS------WNTISSYLQRDIKALKSQLLLGESATSGS 263 Q+G N G WRLR+ +TW+ N SS W I+++L+RDI L+S+L LG+ T G Sbjct: 212 QSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGD 271 Query: 264 IFSSYTFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVPAGAFE 323 IF F G QLASDDNMLP+SQRGFAP + GIA +A VTI+QNGY IY S VP G F Sbjct: 272 IFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFT 331 Query: 324 INDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDS 383 IND+Y + NSGDL+VTI+E+DG+ + F PYSS+P++QR GH +YS TAG YR+ Sbjct: 332 INDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQE 391 Query: 384 KEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDN 443 K P F ++T ++GL +T+YGG ++ Y A GIG +GALGALS+D+ +A++ + Sbjct: 392 K-PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD 450 Query: 444 QHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEA------------------ 485 G R Y K + E+ TNI + YRY+ GYF+F + Sbjct: 451 DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQ 510 Query: 486 ----NTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQ 541 T ++ ++ ++Q ++Q + +LY SGS Q YWG ++ + G++ Sbjct: 511 VKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF 570 Query: 542 WGVGYSLNYQYSRYTDQN-NDRALSLNLSIPLERWLPRSR--------VSYQMTSQKDRP 592 + ++L+Y ++ Q D+ L+LN++IP WL SY M+ + Sbjct: 571 EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGR 630 Query: 593 TQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNS----SLNASYRSPYGTFSAGYSYGNDS 648 + + G+LL+D LSYS++ + NS +YR YG + GYS+ +D Sbjct: 631 MTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDI 690 Query: 649 SQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYL 708 Q YGV+GGV+ H +GVTL Q L + L+ A GA +++N G+ TD GYAV+PY Sbjct: 691 KQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYA 750 Query: 709 TTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPL 768 T Y+ENR+++DT L DNVDL+ VVP RGA+V A F A +G ++L+T+ N KPL Sbjct: 751 TEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL-THNNKPL 809 Query: 769 PFGALASNDETGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTT 828 PFGA+ +++ + IV + G +YLSG+ + V+WG + + C + P Sbjct: 810 PFGAMVTSESSQSSGIVADNGQVYLSGMPLAGK-VQVKWGEEENAHCVANYQLPPESQQQ 868 Query: 829 SVLQGTAQC 837 + Q +A+C Sbjct: 869 LLTQLSAEC 877
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 29.7 bits (66), Expect = 0.011 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 21/160 (13%) Query: 208 VKLSIQGNLTAPQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTS 267 V+++I+GN+ P C IN G I V+FG IN + V +I+ C S Sbjct: 21 VQINIRGNVYIP-PCTINNGQNIVVDFGNINPEHVDNSRG------EVTKNISISCPYKS 73 Query: 268 KIKNSLQMRIDGTTGVVDQYNLVARRRSSDNVPDVGIRIENLGGGVANIPFQNG------ 321 SL +++ G T V Q N++A N+ GI + G + NG Sbjct: 74 ---GSLWIKVTGNTMGVGQNNVLA-----TNITHFGIALYQGKGMSTPLTLGNGSGNGYR 125 Query: 322 ILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVI 361 + + T + P G L G F+ TA++++I Sbjct: 126 VTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMI 165
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.4 bits (68), Expect = 0.030 Identities = 11/72 (15%), Positives = 24/72 (33%), Gaps = 4/72 (5%) Query: 487 AGVNGGSGIALTGSPITLRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGE 546 + V+G + + + I + + ++ T D + G R A + + Sbjct: 330 SEVHGNAEVHASFFDIGGSVSAGFSNSNSS----TVAIDHSLSLAGERTWAETMGLNTAD 385 Query: 547 IAFIKPMIAMRN 558 A + I N Sbjct: 386 TARLNANIRYVN 397
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.6 bits (61), Expect = 0.036 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 22/111 (19%) Query: 42 NKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIA-------NDRL 94 K+L GN + A T + IA + V AI+ D+ Sbjct: 277 TKVL--GNVGKGISQYIIAQRAAQGLSTSAAAAGLIA----SAVTLAISPLSFLSIADKF 330 Query: 95 HD----EVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVA 141 E Y+++ + LG+ GD LLA + A++A++T T++A Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETG-----AIDASLTTISTVLA 376
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.0 bits (176), Expect = 6e-16 Identities = 32/184 (17%), Positives = 63/184 (34%), Gaps = 38/184 (20%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQ 137 + SGV++ K +LTN HV++ L +G ++ + Sbjct: 102 FIASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 138 SDIALLQIQN-------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALG 190 D+A+++ + ++++ + +V G P V+ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 191 RSGLNLEGLEN-FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 250 MART 253 + Sbjct: 264 VFIN 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 52.7 bits (126), Expect = 8e-10 Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKI-------NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + + ++ + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.045 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 164 bits (417), Expect = 4e-55 Identities = 43/141 (30%), Positives = 70/141 (49%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLLAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y L A+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKDLYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 54.4 bits (131), Expect = 2e-10 Identities = 29/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQVLFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG VL + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 127 bits (321), Expect = 6e-39 Identities = 78/209 (37%), Positives = 122/209 (58%), Gaps = 3/209 (1%) Query: 1 MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFN 60 MA++TK EA +TRQ +++ A+ F+Q GVS T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-LQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEF 119 E+W L + ++ EL E A DP LRE LI L+ R++ L++I++HKCEF Sbjct: 61 EIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 NDEM-LAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLDVVMIIIDGAFSGIVQNWL 178 EM + + R + + + L+ C + + +L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNMAGYDLYKQAPALVDNVLRMFMPDENI 207 +DL K+A V +L M++ + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTL 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 2e-06 Identities = 38/217 (17%), Positives = 70/217 (32%), Gaps = 38/217 (17%) Query: 98 ATYQANYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 215 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 270 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 271 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEG 299 G + + ++ N L GM V A I G Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 8e-04 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 46 TAPLEVKTELPGR-TNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQANY 104 +E+ G+ T++ R E++P + IV EG V+ G L ++ +A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVE 164 + K++++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191 Score = 29.0 bits (65), Expect = 0.033 Identities = 11/34 (32%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 65 AEVRPQVSGIVLNRN-FTEGSDVQAGQSLYQIDP 97 + +R VS V TEG V ++L I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1404 bits (3636), Expect = 0.0 Identities = 1029/1034 (99%), Positives = 1030/1034 (99%) Query: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPDITQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 EVQQQGISVEKSSSSYLMVAGFVSDNP TQDDISDYVASNVKDTLSRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRM 780 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKK+YVQADAKFRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLMAVRMHLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 EATLMAVRM LRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVIRRCFKG 1034 VPVFFVVIRRCFKG Sbjct: 1021 VPVFFVVIRRCFKG 1034
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.004 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 1 MKR---LIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGG 57 MK+ L+ + L LA C+ + +V TN+ + T++ IAG Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN-------IAGD 53 Query: 58 AAAVAGLT 65 + + Sbjct: 54 KINLHSIV 61
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 84.6 bits (209), Expect = 2e-21 Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 15/200 (7%) Query: 59 DFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSNDETSFVLINEGSEQKRY 118 DF+L + +N AG DA N L+++L G++ +D S +I++ +EQ Sbjct: 64 DFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSR 122 Query: 119 SLNEALESAPGT--FIRKINKTSVVFETHGHYEKVTLH-------PGLP--DIIKQPDSE 167 +NE + PG I I VV + G YE + L+ G+P + +Q Sbjct: 123 GVNEEV---PGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGAQVNEQLQQR 179 Query: 168 SQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNLSLTHPDEVS 227 + ++DY+ +PI + ++ G RLNP ++F LQ D+A+ +N L L ++ Sbjct: 180 ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAK 239 Query: 228 QALSLLLTQQSAQFTIRRNG 247 +A+ + + T+ R+G Sbjct: 240 KAMERMADVHNFTLTVERDG 259
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 224 bits (573), Expect = 4e-70 Identities = 100/196 (51%), Positives = 143/196 (72%), Gaps = 3/196 (1%) Query: 7 ITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRS 66 +T + AALL A E++ A+F DI++F+ V ++L KT++IDPSV+GTI+VRS Sbjct: 12 LTLLIFAALLF---RPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 67 NDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTSPGMIADSSRPGVGDELV 126 D ++++YYQFFLS+LD+YG++VI ++NG LKVVRS + KT+ +A + PG+GDE+V Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVV 128 Query: 127 TRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDV 186 TR+VPL NV ARDLAPLLRQ+ D VG+VVHYEPSNVL++TGRA+ I +L+ +++RVD Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 187 IGTEKQQIIHLEVSSV 202 G + L +S Sbjct: 189 AGDRSVVTVPLSWASA 204 Score = 159 bits (404), Expect = 4e-46 Identities = 69/129 (53%), Positives = 90/129 (69%), Gaps = 3/129 (2%) Query: 195 IHLEVSSVD---SSSNSTLGPTFNTRTIQNAVLVKTGETVVLGGLLDDFSKEQVSKVPLL 251 I EVSSV SS++S LG TFNTRT+ NAVLV +GETVV+GGLLD + KVPLL Sbjct: 504 IEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLL 563 Query: 252 GDIPLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRSLSKEKYTRYRQEQQQRIDGKS 311 GDIP++G LFR TS + +KRNLM+FIRPT+IRD D YR S +YT + Q ++ ++ Sbjct: 564 GDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKEN 623 Query: 312 KALVGSEDL 320 + ++DL Sbjct: 624 NDAMLNQDL 632 Score = 30.7 bits (69), Expect = 0.008 Identities = 17/98 (17%), Positives = 38/98 (38%), Gaps = 18/98 (18%) Query: 127 TRIVPLENVPARDLAPLLRQM-----------MDAGSVGNVVHYEP---SNVLILTGRAS 172 T+++ L+ A DL +L + ++ + + +N LI+T Sbjct: 269 TKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAPD 328 Query: 173 TINKLIEVIKRVDVIGTEKQQIIHLEVSSVDSSSNSTL 210 +N L VI ++D+ ++ + +E + L Sbjct: 329 VMNDLERVIAQLDI----RRPQVLVEAIIAEVQDADGL 362
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 517 bits (1332), Expect = 0.0 Identities = 195/405 (48%), Positives = 282/405 (69%), Gaps = 8/405 (1%) Query: 2 NYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQK-------SSGVKTRRP 54 Y Y+A+ G+K +G +A+ RQAR LRE GL L + + S+G+ RR Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 55 -RISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLGDVLNQVRSAILEGHPLSD 113 R+S S+L L TRQLATL AA++PLEE+L + +QS L ++ VRS ++EGH L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 114 ALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKLIQSLIYPCMLTTV 173 A++ FP F+ LY +V AGE SG L VL +LADY E RQ++RS++ Q++IYPC+LT V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 174 AIGVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTGPTLLATVFIVAVGFW 233 AI VV ILL+ VVPK+ EQF+HMKQ LPLSTR+L+G+SD ++ GP +L + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 234 LWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQSSGVPLLDGMNLSTESLN 293 + L++ R FH LL + LIG + +N+ARY RTLSIL +S VPLL M +S + ++ Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 294 NLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVASGEKSGQLGTLMVRAADNQE 353 N R RL+ A + VR+G S+H +LEQTA+FPPMM +M+ASGE+SG+L +++ RAADNQ+ Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 354 TLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQLNSMIN 398 +++ L L +FEP L+++MA +VLFIV+++LQP+LQLN++++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 250 bits (639), Expect = 3e-89 Identities = 145/145 (100%), Positives = 145/145 (100%) Query: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145 LSAGPDGEMGTEDDITNWGLSKKKK Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 143 bits (362), Expect = 2e-46 Identities = 50/156 (32%), Positives = 76/156 (48%), Gaps = 22/156 (14%) Query: 3 QQRGFILLEMMLVLALVAITASVVLFTY--GREDVANTRARETAARFTAALELAIDRATL 60 +QRGF LLEMML+L L+ ++A +VL + R+D A +T ARF A L R Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDD----SAAQTLARFEAQLRFVQQRGLQ 57 Query: 61 SGQPVGIHFSDSAWRIMV----PGKTP-------SAWRWVPLQEDAADESQNDWDEELSI 109 +GQ G+ W+ +V G P S +RW+PL+ S + +L++ Sbjct: 58 TGQFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNL 117 Query: 110 HL---QPFKPDDSNQPQVVILADGQITPFSLLMANA 142 + + P D P V+I G++TPF L + A Sbjct: 118 AFAQGEAWTPGD--NPDVLIFPGGEMTPFRLTLGEA 151
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.2 bits (68), Expect = 0.001 Identities = 17/90 (18%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 1 MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQ--RNAIERMRNETLALWIADNQLQSQD 58 +KQ G TLLE+++ + I +A ++ ++ G + ++ ++ +AL A + + D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK-LD 62 Query: 59 SFGEENTSSSGKELING-----EEWNWRSD 83 + T+ + L+ N+ + Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKE 92
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.4 bits (76), Expect = 3e-04 Identities = 12/47 (25%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 4 RQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKEIQQFNQ 50 RQ+GFTLLE+M L + + + + + F + + + + + +F Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRD--DSAAQTLARFEA 46
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 157 bits (399), Expect = 1e-49 Identities = 76/166 (45%), Positives = 98/166 (59%), Gaps = 2/166 (1%) Query: 55 VPLILCVAAAIACALAPFTPIVTSALFLYFCFVLTLSVIDFRTQLLPDKLTLPLLWLGLV 114 V L+ + + T A L ++ L+ ID LLPD+LTLPLLW GL+ Sbjct: 113 VELLTALLSVAVAMTLAPGWG-TLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLL 171 Query: 115 FNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQTL 174 FN G + L DAV GA+AGY VLW +YW L+ KEG+GYGDFKLLAA GAW GWQ L Sbjct: 172 FNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQAL 231 Query: 175 PMILLIASLGGIGYAIVSQLLQRRTITT-IAFGPWLALGSMINLGY 219 P++LL++SL G I LL+ + I FGP+LA+ I L + Sbjct: 232 PIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLW 277
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 35.2 bits (81), Expect = 3e-05 Identities = 28/150 (18%), Positives = 59/150 (39%), Gaps = 24/150 (16%) Query: 5 TKVINYLNKLLGNE---LVAINQYFLHARMFKNWGLKRLNDVEYHESIDEM-----KHAD 56 T V N LN L N ++++ +W +K + HE +E+ + D Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRF--------HWYVKGPHFFTLHEKFEELYDHAAETVD 62 Query: 57 RYIERILFLEGLPN--LQDLGKL------NIGEDVEEMLRSDLALELDGAKNLREAIGYA 108 ER+L + G P +++ + EM+++ + + + IG A Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLA 122 Query: 109 DSVHDYVSRDMMIEILRDEEGHIDWLETEL 138 + D + D+ + ++ + E + L + L Sbjct: 123 EENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 186 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 187 AKILELAGFLDSYIPEPE 204 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.021 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 218 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 219 SK 220 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 132 bits (334), Expect = 5e-40 Identities = 79/226 (34%), Positives = 124/226 (54%), Gaps = 9/226 (3%) Query: 28 AAKPATTADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 11 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 68 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 69 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 118 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 119 RYDALNRYPMSDVLR 133 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.005 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQSRKAELTAC 602 +LE++ + +L A+ + EE+ SE QS + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.0 bits (72), Expect = 0.008 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.5 bits (100), Expect = 2e-06 Identities = 47/275 (17%), Positives = 94/275 (34%), Gaps = 32/275 (11%) Query: 44 PVSQVAFSFGLLSLGLAIS----SSVAGKLQERFGVKRVTIASGILLGLGFFLTAHSDNL 99 + V +G+L A+ + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFAIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDTQLLETVGLEKTFVIWGAIALVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMR 212 L+ F A+ + + G L+ ++ K E + R Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207 Query: 213 --KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQSLAHLDVVSAANAVTVISIAN-LS 265 ++AV F+ + L+VI + H D + ++ I + L+ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 266 GRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 ++ G ++ ++ R + +G + G L FA Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 36.3 bits (84), Expect = 2e-04 Identities = 37/155 (23%), Positives = 64/155 (41%), Gaps = 9/155 (5%) Query: 241 AQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 AH ++ A A+ + A + G L SD+ R V+ + + V A + A Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGAL-----SDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 301 PLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSICGSIIA 360 P V + I VA G T V + +++ + A+++G + FG G + G ++ Sbjct: 94 PFLWVLYIGRI--VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG 151 Query: 361 SLFGGF--YVTFYVIFALLILSLALSTTIRQPEQK 393 L GGF + F+ AL L+ + K Sbjct: 152 GLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.5 bits (61), Expect = 0.045 Identities = 22/117 (18%), Positives = 47/117 (40%), Gaps = 16/117 (13%) Query: 119 SMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLS 178 S+ + D+ + H S + + + R G++ P ++SY F + Sbjct: 228 SVAVQQQDAKLV-EENYSHNSQTEVAATLAYRFGNVTP--RVSYAHGFKGSF-------- 276 Query: 179 RMTATNQNGNWLDVTVGADMLLNQNIAAYAA---LSQAENTTNNSDYLYTMGVSARF 232 ATN N ++ V VGA+ ++ +A + L + + + +G+ +F Sbjct: 277 --DATNYNNDYDQVVVGAEYDFSKRTSALVSAGWLQEGKGESKFVSTAGGVGLRHKF 331
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.5 bits (79), Expect = 5e-05 Identities = 17/52 (32%), Positives = 25/52 (48%), Gaps = 5/52 (9%) Query: 76 VAPKAVRRGIGKALM----QYVQQRHP-HLMLEVYQKNQPAIDFYQAQGFHI 122 VA ++G+G AL+ ++ ++ H LMLE N A FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 114 bits (286), Expect = 2e-32 Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 11/122 (9%) Query: 108 LNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEY--PKTAVNVIGYTDSTGGHDLNMRLS 165 + ++V F+ + ATLKP G L + L +V V+GYTD G N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A +I +G+G +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SP 218 Sbjct: 335 KG 336
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 120 bits (302), Expect = 2e-39 Identities = 50/89 (56%), Positives = 66/89 (74%) Query: 2 NKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRAERTGR 61 NK LI +AE EL+K + AA+++ +A++ L +G+ VQL+GFG F+V RA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIKIAAANVPAFVSGKALKDAVK 90 NPQTG+EIKI A+ VPAF +GKALKDAVK Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 3e-04 Identities = 50/274 (18%), Positives = 100/274 (36%), Gaps = 67/274 (24%) Query: 197 ILFALATVLLA-SVLSFFW-YRRYLRSRQLLQDEMKRKEKLVALGHLAAGV-AHEIRNPL 253 I+F + V S+L F W + + + ++ Q +M + L L A + H + N L Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL 179 Query: 254 SSIKGLAKYFAERAPAGGEAHQLAQVMAKEADRLNRVVSELLELVRPTHLALQAVDLNTL 313 ++I+ L + ++ + +++ L EL+R + L +L Sbjct: 180 NNIRAL--------------------ILEDPTKAREMLTSLSELMRYS-LRYSNARQVSL 218 Query: 314 ------INHSLQLVSQDANSREIQLRFTANDTLPV-IQADPDRLTQVLLNLYL-----NA 361 ++ LQL ++F D L Q +P + + + + N Sbjct: 219 ADELTVVDSYLQL---------ASIQF--EDRLQFENQINPAIMDVQVPPMLVQTLVENG 267 Query: 362 ----IQAIGQHGVISVTASESGAGVKISVTDSGKGIAAGQLEAIFTPYFTTKAEGTGLGL 417 I + Q G I + ++ V + V ++G E TG GL Sbjct: 268 IKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT------------KESTGTGL 315 Query: 418 AVVHNIVEQHGG---TIQVASQEGKGATFTLCLP 448 V ++ G I+++ ++GK + +P Sbjct: 316 QNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 524 bits (1351), Expect = 0.0 Identities = 183/468 (39%), Positives = 253/468 (54%), Gaps = 35/468 (7%) Query: 8 ILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVRERVFDLVLCDVRMAEMDGIAT 67 ILV DDD + T+L L GY+V + ++ + DLV+ DV M + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEIKALNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHSI 127 L IK P +PVL+M+A ++ TA++A + GA DYL KP D L + +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 128 DAETPAVTASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSA 187 ++ + +VG+S AMQ + +A + ++ T++I G+SGTGKELVARA+H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 188 RSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISP 247 R P V +N AA+ L+ESELFGHEKGAFTGA R GRF +A+GGTLFLDEIGD+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 248 MMQVRLLRAIQEREVQRVGSNQTISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAI 307 Q RLLR +Q+ E VG I DVR++AAT++DL +N G FR+DLYYRLNVV + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 308 EVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVER 367 +P LR R EDIP L HF+Q+ + VK F +A++L+ + WPGN+RELEN V R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 368 AVVLLTGEYISERELPLAIASTPIPLGQSQDIQP-------------------------- 401 L + I+ + + S + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 402 --------LVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR 441 L E+E +ILAAL T GN+ +AA LG+ R TL K+ Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 4e-05 Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 78 IDPDVRGCGVGRVLVEHALSMAPE-----LTTNVNEQNEQAVGFYKKVGFKVTG 126 + D R GVG L+ A+ A E L + N A FY K F + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 32.3 bits (73), Expect = 0.004 Identities = 14/58 (24%), Positives = 23/58 (39%) Query: 289 ETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYK 346 ET+ PD+ L A P L Y + N D +T + + QL+++ Sbjct: 544 ETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNAT 601
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 4e-04 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 279 VIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMT--- 335 +I ++ ++ VGI +++ P + + L S D+ I++ + L A + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 336 VDKFGRKPLQIIGALGMAIGMFSLGTA 362 D+FGR+P+ ++ G A+ + TA Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATA 93
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 31.1 bits (70), Expect = 0.011 Identities = 22/124 (17%), Positives = 43/124 (34%), Gaps = 21/124 (16%) Query: 128 GDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDIT 187 ++WQ+ T DA L+L T + L+ + A+ ++ Sbjct: 367 NNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPV---SDAIVNMD 423 Query: 188 AILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQ--------IGFYQS 239 ++ D K+ M+S GD N Q+ + + N++ Y S Sbjct: 424 VLITDEAKIAMAS----------EEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYAS 473 Query: 240 ITAD 243 + +D Sbjct: 474 LVSD 477
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 756 bits (1953), Expect = 0.0 Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK Sbjct: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 Query: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 Query: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 Query: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 Query: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP Sbjct: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 Query: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK Sbjct: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 32 VVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKR 66 VV G G GKSTL+ + GL+ + IG + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.014 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 34/139 (24%), Positives = 60/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARQQAPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+ V + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSSPSPVIRIGHFEL 139 K+ S L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 40/182 (21%), Positives = 73/182 (40%), Gaps = 40/182 (21%) Query: 312 LRQARLENRQEVVLTVVDVAALFR---RVSEARTVQLAE--KNITLHVM--------PTE 358 +R LE+ + + ++ L R R S AR V LA+ + ++ + Sbjct: 182 IRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQ 241 Query: 359 VNVAAEPALLEQALGNLL-----DNA----IDFTPESGRITLSAEVDQEHVALKVLDTGS 409 PA+++ + +L +N I P+ G+I L D V L+V +TGS Sbjct: 242 FENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301 Query: 410 GIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE-VARLFNGEVTLR-NVQEGGVLASL 467 N ++S+G GL V E + L+ E ++ + ++G V A + Sbjct: 302 LALK----------------NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 468 RL 469 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122