>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 41.6 bits (97), Expect = 2e-05 Identities = 39/233 (16%), Positives = 58/233 (24%), Gaps = 32/233 (13%) Query: 329 EVAAPTAVPGSGPAAAAPPVPVTRPAPTERTIAATGPVARSAPPTP------------SR 376 E+A P PA A P A + + T S Sbjct: 1016 EIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSN 1075 Query: 377 LPAAP-----GPIPSRTPTPAPSRTSPPS-----RSASSTPSRTPTAPRQASPPIPPRAR 426 + A S T + T + A +T P+ S P + + Sbjct: 1076 VKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ 1135 Query: 427 AAEGGPAAPATPTSHPGSSKPAPSTGSARTPALAPTPAAEPAPAPRTGRPPRPSREAAVP 486 + P A + P+ + T A PA T + Sbjct: 1136 SETVQPQAEPAR-------ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTT 1188 Query: 487 VADGPGSARRPEPDGPLRPWQESRRGADGLQPREEIPVRLSVRDRARIPLPGS 539 V G PE P Q + +P+ R SVR P + Sbjct: 1189 VNTGNSVVENPENTTPATT-QPTVNSESSNKPKNR--HRRSVRSVPHNVEPAT 1238 Score = 33.1 bits (75), Expect = 0.006 Identities = 42/258 (16%), Positives = 71/258 (27%), Gaps = 23/258 (8%) Query: 2 SDVPQAPYGEEGDARPVSLIGARIPTSASRSNRLPDRDDQYGRDESSTAEDAESPPYARS 61 +DVP P E AR P A+ S + + ES T E E A Sbjct: 1005 ADVPSVPSNNEEIARVDEAPVPP-PAPATPSETTETVAEN-SKQESKTVEKNEQD--ATE 1060 Query: 62 GRRRHRRRGGPDSPQPPDEAWQSEAFHLDDATSATEPGADRAGAADATSPAEPPGAGRGS 121 ++R +E T T+ + E + Sbjct: 1061 TTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK----------ETATVEKEE 1110 Query: 122 QPAPGAEPAEELRRARGSLTRRAGRPAAIAPRNQADPSRRPAPPAGADGAAPESSRDLAA 181 + E +E+ + ++ + + + P QA+P+R P +++ Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQP--QAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 182 PSPAD----GPDHAVGTGTGTRTAGS---GPGAGHGSAAAPTDALAAGPGPTAIPPHTTG 234 PA + V T T S P + PT + P + Sbjct: 1169 EQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVR 1228 Query: 235 SPPLPDAPVGATPPRSRP 252 S P P + Sbjct: 1229 SVPHNVEPATTSSNDRST 1246
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.024 Identities = 12/19 (63%), Positives = 13/19 (68%) Query: 37 LVGPNGAGKSTLIKALLGL 55 L G G GKSTLI L+GL Sbjct: 601 LEGTGGIGKSTLINTLVGL 619
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 84.6 bits (209), Expect = 4e-22 Identities = 40/123 (32%), Positives = 55/123 (44%), Gaps = 6/123 (4%) Query: 51 TLVLSADVLFAFDSAELTATARR---QIADVAGRLAGSAAPIRVDGYTDSFGTPAYNVIL 107 L +DVLF F+ A L + Q+ L + V GYTD G+ AYN L Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGL 273 Query: 108 SQRRASAVADLLRPAAPAGFLVSARGHGSADPIAHDTLPDGSDD---PAGRAINRRVTIT 164 S+RRA +V D L +SARG G ++P+ +T + A +RRV I Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333 Query: 165 YGG 167 G Sbjct: 334 VKG 336
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 30.0 bits (67), Expect = 0.013 Identities = 28/159 (17%), Positives = 52/159 (32%), Gaps = 14/159 (8%) Query: 170 LAGRRVGISGVGK-VGRRLVGHLVEDGASVIAADVDPAALARLRAEFPTAQTVADPDELF 228 + G+ I+G + +G + L GA + A D +P L ++ + A+ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE----- 60 Query: 229 DLELDVYSPCALGGVLD--AETVGRLRAEIVCGGANNQLATPEIGGRLAEAGVLYTPDFV 286 DV A+ + +G + + G + EA F Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEA------TFS 114 Query: 287 VNAGGLIQVADEIEGYSPQRARARAARIFDTTAEVLRLA 325 VN+ G+ + + Y R + A V R + Sbjct: 115 VNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTS 153
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 31.0 bits (70), Expect = 0.004 Identities = 12/61 (19%), Positives = 22/61 (36%), Gaps = 17/61 (27%) Query: 19 VWNYWLGGKDHYPVDREFGDRLYELLPEIVQ--IARQARAFLGRAVTYLAGEVGIRQFLD 76 ++ WL G + P IVQ +A + V + G ++++D Sbjct: 71 IFICWLQGIEK--------------APYIVQQCVASVKKNSGDFKVIIIDGN-NYKEWVD 115 Query: 77 I 77 I Sbjct: 116 I 116
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.5 bits (128), Expect = 2e-11 Identities = 30/190 (15%), Positives = 71/190 (37%), Gaps = 21/190 (11%) Query: 1 MFSELGLSA-TVPDVAARAGVGKATVYRNFPSRDELLTAVVERQL-QWFDTIATTALHDP 58 +FS+ G+S+ ++ ++A AGV + +Y +F + +L + + E + P Sbjct: 23 LFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFP 82 Query: 59 -DPATGFEMLITSWFDRLV---ANRLVQDVMRLRTLASAEIQIDR---------ITTLVD 105 DP + ++ + V RL+ +++ + E+ + + ++ Sbjct: 83 GDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIE 142 Query: 106 RVVVRAQRAGAVRLDVTPADLRTMMSGCAQRLVETGQQDIDSRLR------FTRLILDAF 159 + + A + D+ +M G L+E S + ++L+ + Sbjct: 143 QTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMY 202 Query: 160 RPPATAATPA 169 T PA Sbjct: 203 LLCPTLRNPA 212
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (310), Expect = 1e-32 Identities = 77/425 (18%), Positives = 180/425 (42%), Gaps = 21/425 (4%) Query: 34 AIPDMARELDSSVSNVTWTMSGYLVAAAVLTPIIGRLGDMFGKRRMLVMSLAIFALGGVV 93 ++PD+A + + ++ W + +++ ++ T + G+L D G +R+L+ + I G V+ Sbjct: 36 SLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVI 95 Query: 94 AALA-AQLPLVIVGRILQGAGGGIFPLCFGIIRDEF-PVEKRSVSIGLISAVTGLGGGLG 151 + + L+I+ R +QGAG FP ++ + P E R + GLI ++ +G G+G Sbjct: 96 GFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVG 155 Query: 152 LVLGGLFVDHATYHWIFWSGAAMAALAAVGSQLLIPESPTRVPGRIDVVGTLLLSVGLAL 211 +GG+ + HW + M + V + + + R+ G D+ G +L+SVG+ Sbjct: 156 PAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213 Query: 212 PLLAISQGKSWGWTSPTTLGMIIGGIVVLAGLLAFERRQAEPLIDVAILARRSVLTTNVS 271 +L + S + + L +I + R+ +P +D + + + Sbjct: 214 FMLFTTS-YSISFLIVSVLSFLI--------FVKHIRKVTDPFVDPGLGKNIPFMIGVLC 264 Query: 272 TLLVGFGMFGAFLLIPQLAQTPKASGYGFGASATTAG-LLMVPGALMMLVTGPLATVISR 330 ++ + G ++P + + S G +++ PG + +++ G + ++ Sbjct: 265 GGIIFGTVAGFVSMVPYMMKD------VHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVD 318 Query: 331 RFGGRAALFTGSLLATVGLVLLAGVP-GSQGALIVECIVLFGGIGMVFAAIPNLIVDAVP 389 R G L G +V + + + + + + + + GG+ I ++ ++ Sbjct: 319 RRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLK 378 Query: 390 AAKTGEATGVNTLLRSVGASLGSQICASILVSQADATGLPTSDAYQTAFVVSAVVALVAG 449 + G + + G I +L L + Q+ ++ S ++ L +G Sbjct: 379 QQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTYLYSNLLLLFSG 438 Query: 450 LAALT 454 + ++ Sbjct: 439 IIVIS 443
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.8 bits (67), Expect = 0.013 Identities = 12/28 (42%), Positives = 17/28 (60%) Query: 151 VLVCGAAGSVGRLAVELLLDRGARVHGL 178 LV GAAG +G + LL+ G +V G+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 1e-13 Identities = 25/171 (14%), Positives = 57/171 (33%), Gaps = 8/171 (4%) Query: 7 NRDETWKRVRAAGVSLLYRHGFEAMNTRQLAEAAGLKPGSLYYYFSSKEDFLHRLLVDLL 66 ET + + + L + G + + ++A+AAG+ G++Y++F K D + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 67 DEILLDLEQNLEGLT-EPVSRLEAYVRTLVRWHVVRREETFIASIEVRS-LTHDRQESYL 124 I + +P+S L + ++ V + I Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 125 QRRDRFDL----ILAEILQDGAAAGIFDLTH-PRITRNAILSSLT-AISSW 169 Q + L + + L+ A + R + ++ + +W Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 54.7 bits (131), Expect = 4e-11 Identities = 43/190 (22%), Positives = 82/190 (43%), Gaps = 5/190 (2%) Query: 5 VLITGASAGLGAGMARIFAARGADLAITARRLDRLNELRTAVVTEHPGRTVVTYALDVND 64 ITGA+ G+G +AR A++GA +A ++L ++ +++ E R + DV D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAEAFPADVRD 68 Query: 65 HDAVFEAFEAAAQHLGHLDRIVVNAGLGKGSAVGAGHLRGNRDTALTNFVGGIAQCEAAM 124 A+ E + +G +D +V AG+ + + + T N G + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 125 RILYRQGRGQLVVISSVVAARGMPGPMNVYAASKVALTHLAEGIRGDVRAKGLPITVSTI 184 + + + G +V + S A M YA+SK A + + ++ I + + Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTS-MAAYASSKAAAVMFTKCLGLELAEYN--IRCNIV 185 Query: 185 RPGYIDSEMQ 194 PG +++MQ Sbjct: 186 SPGSTETDMQ 195
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.1 bits (210), Expect = 4e-22 Identities = 71/237 (29%), Positives = 106/237 (44%), Gaps = 12/237 (5%) Query: 2 SRRLADDGWSVVVVDIVPEGARAVAESITSVGGRAVVAVADISDPARVDELRDEAAAAFG 61 +R LA G + VD PE V S+ + A AD+ D A +DE+ G Sbjct: 25 ARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAIDEITARIEREMG 84 Query: 62 RPVAALVNLAGAVRNSVLSKLSDADFELVLRTHLFATMHTVRAFGPGMKAAGFGRIVNTS 121 P+ LVN+AG +R ++ LSD ++E + + R+ M G IV Sbjct: 85 -PIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVG 143 Query: 122 SVAARGVVAGIS-YSSAKGGIEGLTRSAAVELARHGVTVNCIEPGVIATGMFLGTPA-EF 179 S A ++ Y+S+K T+ +ELA + + N + PG T M A E Sbjct: 144 SNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADEN 203 Query: 180 QAAQVAQ---------IPVGRAGHPEEIAAAVSFLVSPESAYITGQTLTVCGGLSVG 227 A QV + IP+ + P +IA AV FLVS ++ +IT L V GG ++G Sbjct: 204 GAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATLG 260
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.9 bits (64), Expect = 0.049 Identities = 36/131 (27%), Positives = 57/131 (43%), Gaps = 11/131 (8%) Query: 2 AARAVARAVAERTREAQRQAEAMTEAIRVAAQRDLADALGPVEARAAAAEAATTRLSAAA 61 AA A A+A A R QR + + EA+R A R A A AA +A RL A Sbjct: 76 AAEAQAKAKANRDALTQRLKDIVNEALRHNASRT-PSATELAHANNAAMQAEDERLRLAK 134 Query: 62 AHIERQTNARLAEQARQ--------IAGLRVETAERFDAAQREFRAALRAERDGREQAME 113 A + + A AE+A Q I + ET + A+ E + + + A+E Sbjct: 135 AEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEAK--AVE 192 Query: 114 SLRAEIRSARA 124 + ++ +A++ Sbjct: 193 IAQKKLSAAQS 203
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 35.3 bits (81), Expect = 0.001 Identities = 15/93 (16%), Positives = 21/93 (22%) Query: 1110 VPAPPAARLPEPAATERSDAVPTEPAPTEPAPTEPAPTEPAPTEPAPTGAVPGVPPPAEP 1169 PP + EP P + AP +P P V P Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESR 124 Query: 1170 AGVASAGSGGWAGDGAQATTAHSAGGPGEQAVA 1202 + + AT A S + Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGP 157 Score = 34.2 bits (78), Expect = 0.002 Identities = 22/118 (18%), Positives = 27/118 (22%), Gaps = 4/118 (3%) Query: 1097 RALLQRLAPRESAVPAPPAARLPEPAATERSDAVPTEPAPTE---PAPTEPAPTEPAPTE 1153 L A S PA L P A + EP P P P + AP + Sbjct: 40 VIELPAPAQPISVTMVAPAD-LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK 98 Query: 1154 PAPTGAVPGVPPPAEPAGVASAGSGGWAGDGAQATTAHSAGGPGEQAVAGTNPDEPWR 1211 P P V +P A A A + Sbjct: 99 PKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 33.0 bits (75), Expect = 0.006 Identities = 15/105 (14%), Positives = 23/105 (21%), Gaps = 5/105 (4%) Query: 1077 ADQPASEAARTRAEAYGPDARALLQRLAPRESAVPAPPAARLPEPAATERSDAVPTEPAP 1136 AD +A + E P + E AP +P + P + Sbjct: 58 ADLEPPQAVQPPPE---PVVEPEPEPEPIPEPPKEAPVVI--EKPKPKPKPKPKPVKKVE 112 Query: 1137 TEPAPTEPAPTEPAPTEPAPTGAVPGVPPPAEPAGVASAGSGGWA 1181 +P + PA A P Sbjct: 113 QPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGP 157 Score = 32.3 bits (73), Expect = 0.009 Identities = 20/105 (19%), Positives = 29/105 (27%), Gaps = 2/105 (1%) Query: 1103 LAPRESAVPAPPAARLPEPAATERSDAVPTEPAPTEPAPTEPAPTEPAPTEPAPTGAVPG 1162 A P + + PA E AV P P EP P P P + AP + Sbjct: 39 QVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPI-PEPPKEAPV-VIEK 96 Query: 1163 VPPPAEPAGVASAGSGGWAGDGAQATTAHSAGGPGEQAVAGTNPD 1207 P +P D + ++ T+ Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 43.2 bits (101), Expect = 2e-06 Identities = 44/153 (28%), Positives = 60/153 (39%), Gaps = 19/153 (12%) Query: 336 VVERVADVLTRLHDAGHSHRALTPDGVILTTPRGTPTLRDLGLVGVRRRPGEGPA----E 391 + R+ DV L AG H + P V+ G P + DLGL R GE P Sbjct: 250 IAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGL---HSRSGEQPKGFTES 306 Query: 392 YRAPEQERLGFHRPEVGFRTDVHRLAAMAYHCLTGRPAGGLPAPLRAFGF--DVPAE-LD 448 ++APE LG ++DV + + HC+ G P + F PA +D Sbjct: 307 FKAPE---LGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMD 363 Query: 449 EVLLAALDSDPDRRPGRPGLLIPALRAGTDHLA 481 E + P RPG G+ R TD L Sbjct: 364 E------NGYPIHRPGIAGVETAYTRFITDILG 390
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 103 bits (259), Expect = 7e-29 Identities = 71/247 (28%), Positives = 105/247 (42%), Gaps = 14/247 (5%) Query: 6 VVVTGAAAGIGEATVELFAERGFGVVAVDVSEEGLAKLGTRADVV-----TLVGDVADPA 60 +TGAA GIGEA A +G + AVD + E L K+ + DV D A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 61 TNDAMVALAVERFGRLDAAVLNAGLGGAPPIEAAGATESLDTIYAVNVRGLVLGIRAAAP 120 D + A G +D V AG+ I + + E + ++VN G+ R+ + Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSL-SDEEWEATFSVNSTGVFNASRSVSK 129 Query: 121 ALRAAGGGSIVVTSSGAGLRGDPYTWAYNTTKAAANNLVRSAALDYAFEGIRINAVAPGL 180 + GSIV S AY ++KAAA + L+ A IR N V+PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 181 TET--------PRTAGQRADPAFAAAVTRRVPLGRWAQPAEQAEVIYFLASPAASYITGA 232 TET ++ +PL + A+P++ A+ + FL S A +IT Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMH 249 Query: 233 VIPVDGG 239 + VDGG Sbjct: 250 NLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 47.7 bits (113), Expect = 3e-07 Identities = 44/165 (26%), Positives = 63/165 (38%), Gaps = 9/165 (5%) Query: 3236 GGTVLITGGTGALGGHVARWLAREGAAHLLLTSRRGERAPGAADLAAQLRALGARVTIAA 3295 G ITG +G VAR LA +G AH+ E+ + + L+A Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQG-AHIAAVDYNPEK---LEKVVSSLKAEARHAEAFP 63 Query: 3296 VDVGDRAALAEVISGIPVEL-PLRAVVHTAAVLDDGLVSELTLEQIDRVLRVKVGGALNL 3354 DV D AA+ E+ + I E+ P+ +V+ A VL GL+ L+ E+ + V G N Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 3355 HELT----RDADLAAFVLFSSIAGTAGITGQGNYAPGNAFLDAFA 3395 D + V S T YA A F Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 27.6 bits (61), Expect = 0.040 Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 13/82 (15%) Query: 155 GNNRELVHWVHDSLRR--QIDAWRVV-------GIFATPVP-VPDDADEWTRLIALTGR- 203 G +E V+ + R+ Q+D W+ I +P + A WT L + G Sbjct: 43 GKTKERVYLAEEGGRKVSQLD-WKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNM 101 Query: 204 -SPDWRPRLDPGRHLDRGRHPD 224 DW +PG D RHPD Sbjct: 102 VDQDWMDSSNPGTWTDESRHPD 123
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.2 bits (62), Expect = 0.032 Identities = 24/77 (31%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 12 PAPNTPPAGAAPSASGGPRPSSPEPERPASAPALN---GHSPAAPPLTATSPSA------ 62 P P+ P G+A + + P P E PA+ PA N G P P +P A Sbjct: 311 PRPDLTP-GSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDG 369 Query: 63 --ATSPTSPTSAPEPSG 77 T P SP P+G Sbjct: 370 QPGTRPDSPAVPDRPNG 386
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 30.6 bits (69), Expect = 0.005 Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 152 VEQLTGFDEGPMRDDWQEQFARRGITVRTDV 182 + +L D+G R D +RGIT++T + Sbjct: 30 ITELGSVDKGTTRTDNTLLERQRGITIQTGI 60
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (266), Expect = 8e-30 Identities = 67/256 (26%), Positives = 108/256 (42%), Gaps = 14/256 (5%) Query: 15 RTVVVTGASGGIGSEIVNRFLAHGDTVVAADVSQEALDTWRARWDSGAPGGRHPSLHAVA 74 + +TGA+ GIG + + G + A D + E L+ + S RH A Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVS---SLKAEARHAE--AFP 63 Query: 75 TDIASEESVAALVQVVQQSLGTVDVLINNAGRFPQTAFEEMSTDEWRQVIDVNLTGTFLM 134 D+ ++ + +++ +G +D+L+N AG +S +EW VN TG F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 135 IRAFVPLLKASGRGRVVNIGSGSVFSGTPMQSHYVASKGGVLGLTRVLARELGGYGITVN 194 R+ + G +V +GS + Y +SK + T+ L EL Y I N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 195 VITPGLTVTPAAAAVLPEALLAEQRDARALHRDET---------PEDLVGPIFFLASDDA 245 +++PG T T ++ + AEQ +L +T P D+ + FL S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 246 AFVTGQTLNVDGGRHL 261 +T L VDGG L Sbjct: 244 GHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 3e-16 Identities = 37/208 (17%), Positives = 63/208 (30%), Gaps = 21/208 (10%) Query: 16 QRRAELLDAAVEYAAEYGFSELTWRPVAAALGVSPTTLVHHFGTKEQMLEAILGRLRERI 75 + R +LD A+ ++ G S + +A A GV+ + HF K + I I Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 76 FAATRDLAGEQP-DLAAEARASWTRAFD-PQHEAEFRLFFAVYGRALQAPQQFA------ 127 + + P D + R + E RL + + + A Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 128 -AFLEHVVAYWMRALVAAQG-----PDTDPATATRTATLVIATIRGLLLDLLATGDRNRV 181 + L D A A ++ I GL+ + L + Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRA---AIIMRGYISGLMENWLFAPQSFDL 187 Query: 182 QDAADCF----LATLERPATVERPATVE 205 + A + L T+ PAT E Sbjct: 188 KKEARDYVAILLEMYLLCPTLRNPATNE 215
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 41.3 bits (97), Expect = 2e-06 Identities = 20/83 (24%), Positives = 35/83 (42%), Gaps = 11/83 (13%) Query: 1 MRVFVTGASGWVGRGLVPDLITAGHTVTGL---------ARSDAATVALRAAGAEVREGS 51 M+ VTGA+G++G + L+ AGH V G+ + A L G + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LDDLDILRE--AAVAADGVIHLA 72 L D + + + A+ + V Sbjct: 61 LADREGMTDLFASGHFERVFISP 83
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 72.6 bits (178), Expect = 4e-15 Identities = 52/315 (16%), Positives = 111/315 (35%), Gaps = 30/315 (9%) Query: 188 SVFIGFAAALIILALVFRTVAATVLPLASAVVALVSGLGVIYILSHAINVSNITPYLAEL 247 ++F +++ L + + AT++P + V L+ ++ ++IN + + Sbjct: 343 TLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTM---FGMV 399 Query: 248 MVIGVGVDYALFIVTR-HRRNLRRGMPVAESIVNAINTSGRAVLFAGTTVCIAILGLIAL 306 + IG+ VD A+ +V R + +P E+ +++ A++ + + + Sbjct: 400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFF 459 Query: 307 GVS---FFNGMAVATALAVGFTMIASLTLLPALLSLFGLKVLPRR----QRAAVRAGEFI 359 G S + ++ A+ +++ +L L PAL + LK + + Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPALCATL-LKPVSAEHHENKGGFFGWFNTT 518 Query: 360 DDRPVGYWARWSQFVARRRVVVAIASGAVMVVIALPFFSLELGASDQGSDAKSFTTR--A 417 D V ++ + + ++V + L L SF Sbjct: 519 FDHSVNHYTNSVGKILGSTGRYLLI--YALIVAGMVVLFLRLP--------SSFLPEEDQ 568 Query: 418 GYDLIAADFGVGYNSTLEAVVSGPGASDQAYLQRVTKSLAAVPGVDPASLGTAPLAKDIA 477 G L G +T E YL+ ++ +V V+ S +A Sbjct: 569 GVFLTMIQLPAG--ATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMA 626 Query: 478 FVTFKTTTSPQSEKT 492 FV+ K P E+ Sbjct: 627 FVSLK----PWEERN 637 Score = 44.1 bits (104), Expect = 2e-06 Identities = 33/178 (18%), Positives = 72/178 (40%), Gaps = 13/178 (7%) Query: 170 EFTGNAFAGIGQSSGSGSSVFIGFAAALIILALVFRTVAATVLPLASAVVALVSGLGVIY 229 ++TG ++ + + + V I F + LA ++ + + V + + +V L Sbjct: 857 DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAAT 916 Query: 230 ILSHAINVSNITPYLAELMVIGVGVDYALFIVTRHRRNLRR-GMPVAESIVNAINTSGRA 288 + + +V + + L IG+ A+ IV + + + G V E+ + A+ R Sbjct: 917 LFNQKNDVYFM---VGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRP 973 Query: 289 VLFAGTTVCIAILGLIALGVSFFNGMAVATALAVGF------TMIASLTLLPALLSLF 340 +L T ILG++ L +S G A+ +G + ++ +P + Sbjct: 974 ILM---TSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 41.4 bits (97), Expect = 2e-05 Identities = 38/189 (20%), Positives = 72/189 (38%), Gaps = 25/189 (13%) Query: 520 DTAINVDFASVLARKMPLFIAVV-VGLSFILLLIAFRSLVIPLTAAVMNLLAAGGSFGLV 578 DT V S+ LF A++ V L L L R+ +IP A + LL G+F + Sbjct: 328 DTTPFVQ-LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLL---GTFAI- 382 Query: 579 VAIFQYGWLSDAMGAGPGGPIDAWIPVMLFAILFGLSMDYQVFLVSRMHEEWVHTRDNTR 638 + +G+ + + + + GL +D + +V + + + + Sbjct: 383 --LAAFGYSINTL------------TMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPK 428 Query: 639 SVTI-GQGETGGIITAAAIIMIAVFLGFVVSPGRPIKI---FGTGLAAAVFLDAFVLRTM 694 T + G + A+++ AVF+ G I F + +A+ L V Sbjct: 429 EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALI- 487 Query: 695 LVPSVMHIV 703 L P++ + Sbjct: 488 LTPALCATL 496
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.8 bits (74), Expect = 0.005 Identities = 23/65 (35%), Positives = 34/65 (52%), Gaps = 9/65 (13%) Query: 115 LAVAHALSQAHRFGIAHRDVKPANILFT-GSGLPKLTDFGIAKILEGTAGEASRLAGTPR 173 L V + L++A G+ H D+KP N++F SG P + D G L +GE + T Sbjct: 255 LDVTNHLAKA---GVVHNDIKPGNVVFDRASGEPVVIDLG----LHSRSGEQPK-GFTES 306 Query: 174 YMAPE 178 + APE Sbjct: 307 FKAPE 311
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 33.9 bits (77), Expect = 0.002 Identities = 15/30 (50%), Positives = 22/30 (73%), Gaps = 1/30 (3%) Query: 127 EAGVLHRDVKPDNVLFTVA-GQPKLTDFGI 155 +AGV+H D+KP NV+F A G+P + D G+ Sbjct: 263 KAGVVHNDIKPGNVVFDRASGEPVVIDLGL 292
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 34.7 bits (79), Expect = 0.002 Identities = 44/158 (27%), Positives = 66/158 (41%), Gaps = 25/158 (15%) Query: 133 LAVADALVQAHGLGVLHRDIKPDNILFTTA-GQPKLTDFGI-ARMFDDPATVARGVIGTP 190 L V + L +A GV+H DIKP N++F A G+P + D G+ +R + P T Sbjct: 255 LDVTNHLAKA---GVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGF------TE 305 Query: 191 RYMAPE-QIREAALGPATDLYALGVTLYELMTGGPLFPPELSVPELLRHHCEVPAPV--- 246 + APE + +D++ + TL + G PE+ + LR PA V Sbjct: 306 SFKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEK-NPEIKPNQGLRFITSEPAHVMDE 364 Query: 247 ---PVTVPEPIG------RVVLRALAKDPAARPPSARA 275 P+ P G R + L +RP S A Sbjct: 365 NGYPIHRPGIAGVETAYTRFITDILGVSADSRPDSNEA 402
>cloacin#Cloacin signature. Length = 551 Score = 32.4 bits (73), Expect = 0.003 Identities = 23/98 (23%), Positives = 29/98 (29%), Gaps = 7/98 (7%) Query: 228 GATAGPGSAGAGARVGAGTGVGAQAGQSGTGVGATAPGAGVGASAGPGGLGLGASAPGTG 287 G G S G G+G + G G+ +G G G G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGG 67 Query: 288 VGAQTGQSGVGLGATVPGAGVGASAGPNGLGLGASAAP 325 G G SG G + A A P G A + P Sbjct: 68 NGNSGGGSGT-------GGNLSAVAAPVAFGFPALSTP 98
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 67.8 bits (165), Expect = 2e-15 Identities = 51/200 (25%), Positives = 78/200 (39%), Gaps = 26/200 (13%) Query: 54 ITLITGANKGLGYESARRLREAGHTVLLAARDPERGQAAAGELAVPFVH-----LDVTDE 108 I ITGA +G+G AR L G + +PE+ + L H DV D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 109 DSVALAASWVRDQYGRLDVLVNNAGINGPSIPIDQATAADVAGVFNTNLLGVVRVTTAFL 168 ++ + + + G +D+LVN AG+ P I + + F+ N GV + + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPG-LIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 169 PLLRASDNPRIVNVSSGTGSFALTEKNSWWDPEYVPPI----YAATKTALTKLTVFYAHA 224 + + IV V S +P VP YA++K A T Sbjct: 129 KYMMDRRSGSIVTVGS--------------NPAGVPRTSMAAYASSKAAAVMFTKCLGLE 174 Query: 225 LPD--MRVNAADPGWTATDL 242 L + +R N PG T TD+ Sbjct: 175 LAEYNIRCNIVSPGSTETDM 194
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 30.3 bits (68), Expect = 0.002 Identities = 29/152 (19%), Positives = 53/152 (34%), Gaps = 30/152 (19%) Query: 3 ADTIVDTTPHRAQILQSAELYDISTQSCHATR--HTEAPPALIDIELNTNASLEAAGL-- 58 ADT P +Q + D+S ++ + + P + +L+T A L Sbjct: 10 ADTQATQQPVLQ--IQRIYVKDVSFEAPNLPHIFQQDWEPK-LSFDLSTEAKQVGDDLYE 66 Query: 59 -DVTVTCQCAIRGDDQSSVADIGLTILVRYAFPADFNRA----AFSIDQEGELHVLRAS- 112 + ++ + + AF + +A +++ H L + Sbjct: 67 VCLNISVETTMESSGDV-------------AFICEVKQAGVFTISGLEEMQMAHCLTSQC 113 Query: 113 ----FPYLREGIQSLAARLGIPGIALGPIAVD 140 FPY RE + SL R P + L P+ D Sbjct: 114 PNMLFPYARELVSSLVNRGTFPALNLSPVNFD 145
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 35.5 bits (81), Expect = 0.001 Identities = 15/26 (57%), Positives = 17/26 (65%), Gaps = 2/26 (7%) Query: 5 PAPDPD--PDPDPDQFGQSGSLPDWP 28 P PDPD PD +PD GQ G+ PD P Sbjct: 353 PEPDPDLNPDANPDTDGQPGTRPDSP 378
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 26.2 bits (57), Expect = 0.020 Identities = 8/26 (30%), Positives = 15/26 (57%), Gaps = 4/26 (15%) Query: 53 WTID----ADQCRLTVWRRRVEYGYC 74 W ID ++ ++TVW + ++ G C Sbjct: 163 WKIDRLGQGEKSKITVWVKPLKEGCC 188
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.9 bits (75), Expect = 0.002 Identities = 25/188 (13%), Positives = 55/188 (29%), Gaps = 7/188 (3%) Query: 133 VLDGSKAEMARIGLTVDALQIQS-IDDGRLGYIAAIAAPHNAAIQRQAQIAQAEANQAAA 191 V +G + L + AL ++ + + A + Q E N+ Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE----QTRYQILSRSIELNKLPE 167 Query: 192 EAEQRSQRAQAEYARQTSIVQAQYRAEIDRAQAEAAQA-GPLAQAQAEVAVTAARTELAE 250 Q + + + + + Q + Q L + +AE AR E Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 251 REAQLRQQQLVTEVVKPAEAEAERVRVLALAEAEKMRIQAEAAASHNRVALDRMLIDQLP 310 +++ + +L + + VL E + + E +++ I Sbjct: 228 NLSRVEKSRLDDFSSLLHKQAIAKHAVLEQ-ENKYVEAVNELRVYKSQLEQIESEILSAK 286 Query: 311 EIVRQAAS 318 E + Sbjct: 287 EEYQLVTQ 294
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.5 bits (100), Expect = 2e-06 Identities = 92/406 (22%), Positives = 155/406 (38%), Gaps = 29/406 (7%) Query: 26 LRRNEGFRMLWTGQLLSDTGSGIGLLAYPLLILALTHSAVLA---GVVGTSRAMTLLCLQ 82 ++ N ++ + L G G+ + P L+ L HS + G++ A+ Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 83 LPAGALADRFDRRLTMIICDTMRAALLALLGILIATDLASWPVVLVVCLIEGGAGAIFNP 142 GAL+DRF RR +++ A A+ ++AT W V+ + ++ G GA Sbjct: 61 PVLGALSDRFGRRPVLLV----SLAGAAVDYAIMATAPFLW-VLYIGRIVAGITGATG-A 114 Query: 143 AAAAVLPGIVPDGQLEQASAATETRTYAAALAGPALGGALFGLGQAVPFLANAVSYVVSF 202 A A + I + + +AGP LGG + G PF A A ++F Sbjct: 115 VAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNF 174 Query: 203 GTVNRIRGRFRPENVAERKALWREVADGL-QFVWQ-----VPILRAVAITAPLMNFAFTG 256 T + + ER+ L RE + L F W V L AV L+ Sbjct: 175 LTGCFL---LPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVG-QVPA 230 Query: 257 VIFTVTLALRHHGTSTAVLGLVQATIAAGGLLGAVVAPRLQGRMRLGALATTITLAGALL 316 ++ + R H +T + ++AA G+L ++ + G + + G + Sbjct: 231 ALWVIFGEDRFHWDATT----IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIA 286 Query: 317 FGAAAPLLP---SPLVAAPIALALLLAPAVNAALFAVTLRSAPAEMRGRVINTVVMATTA 373 G LL +A PI + L AL A+ R E +G++ ++ T+ Sbjct: 287 DGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSL 346 Query: 374 LAALAPLTAGLLVQHVSGAWTVGAFAATAATAAVLCLILPGLRNAA 419 + + PL + W A+ A AA+ L LP LR Sbjct: 347 TSIVGPLLFTAIYAASITTWNGWAW---IAGAALYLLCLPALRRGL 389
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 29.4 bits (65), Expect = 0.035 Identities = 16/43 (37%), Positives = 20/43 (46%) Query: 292 PRSPSGPPTTRPDPPTTPVPTRSPATTASTPTPIPPDGRDEGS 334 PR+P PP RP + AT ST +P P+ R E S Sbjct: 156 PRTPPLPPRERPHTSGHHGAGEARATAPSTVSPYGPEARAELS 198
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.9 bits (70), Expect = 0.003 Identities = 17/92 (18%), Positives = 35/92 (38%), Gaps = 18/92 (19%) Query: 3 RIVIFGAGGQIGRRITDEAIRRGHEVTAVEVDA---------ARVKKLPRKA-NAVEGDV 52 + ++ GA G IG ++ + GH+V ++ AR++ L + + D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 53 TSRDSVQRLAQEADAVVVAVGGVDRPVHANAA 84 R+ + L A G +R + Sbjct: 62 ADREGMTDL--------FASGHFERVFISPHR 85
>cloacin#Cloacin signature. Length = 551 Score = 28.9 bits (64), Expect = 0.026 Identities = 16/30 (53%), Positives = 16/30 (53%), Gaps = 1/30 (3%) Query: 181 GIGDGDGGTDGGGGTGGGGGTSGDGGGTDG 210 G G GG G G GGG G SG G GT G Sbjct: 51 GSGIHWGG-GSGHGNGGGNGNSGGGSGTGG 79 Score = 28.5 bits (63), Expect = 0.030 Identities = 12/23 (52%), Positives = 12/23 (52%) Query: 185 GDGGTDGGGGTGGGGGTSGDGGG 207 G G GGG G GG SG GG Sbjct: 58 GGSGHGNGGGNGNSGGGSGTGGN 80 Score = 28.1 bits (62), Expect = 0.044 Identities = 19/53 (35%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 181 GIGDGDGGTDGGGGTGGGGGTSGDGGGTDGIVDGRVVGTYLHGPVLAQNPALA 233 G G G G GGG G GG +G+ GG G + + PV PAL+ Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN---LSAVAAPVAFGFPALS 96
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.5 bits (63), Expect = 0.028 Identities = 16/53 (30%), Positives = 23/53 (43%), Gaps = 2/53 (3%) Query: 113 SVASLRRDLAALLAEHARAEDGLLRELTERLSDADRQHLVDRFADAMRHAPTR 165 S A L++ A A A + + R DA Q L D +A+RH +R Sbjct: 58 STAQLKKTQAEQAARAKAAAEAQAKAKANR--DALTQRLKDIVNEALRHNASR 108
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.9 bits (140), Expect = 2e-11 Identities = 27/125 (21%), Positives = 49/125 (39%), Gaps = 1/125 (0%) Query: 13 ILLVEDDDADAYLVSELLDEVAAPVELTRVRTVAEAVRRSKQVSCVLLDLGLPDSEGLSA 72 IL+ +DD A ++++ L V +T + V+ D+ +PD Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 73 LRRLLAVEAGAPVVVLTGLVDEYRGAQAVAAGAQDYLVKGQVDGRDLVRAVRYAIERKRA 132 L R+ PV+V++ +A GA DYL K D +L+ + A+ + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK-PFDLTELIGIIGRALAEPKR 124 Query: 133 DTAAQ 137 + Sbjct: 125 RPSKL 129
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.7 bits (142), Expect = 5e-13 Identities = 19/123 (15%), Positives = 49/123 (39%), Gaps = 11/123 (8%) Query: 10 VLLVEDDPGDVLMTREAFEDHKLRNHLNVVSDGVEALAYLRGEGEYAGSPRPDLILLDLN 69 +L+ +DD + +A + S+ ++ DL++ D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVR--ITSNAATLWRWIAAGD-------GDLVVTDVV 56 Query: 70 LPRRDGREVLREVKADERLRRIPVVVLTTSEAEEDVLRSYDLHANAYITKPVDFERFVAV 129 +P + ++L +K + +PV+V++ +++ + A Y+ KP D + + Sbjct: 57 MPDENAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 130 VRH 132 + Sbjct: 115 IGR 117
>cloacin#Cloacin signature. Length = 551 Score = 33.5 bits (76), Expect = 8e-04 Identities = 23/76 (30%), Positives = 26/76 (34%), Gaps = 1/76 (1%) Query: 11 GYPQGGHDQGGQGQGGYGPGQDQGQGGYGQGQGGYEQGQGGYGQGQGGYEQGQGGYGPGP 70 G+ G H G GG G G G GG G G G + G G+G G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGG-GSGSGIHWGGGSGHGNGG 66 Query: 71 GQSQGGYGQGGYGPGQ 86 G G G G G Sbjct: 67 GNGNSGGGSGTGGNLS 82 Score = 31.6 bits (71), Expect = 0.003 Identities = 29/104 (27%), Positives = 35/104 (33%), Gaps = 6/104 (5%) Query: 20 GGQGQGGYGPGQDQGQGGYGQGQGGYEQGQGGYGQGQGGYEQGQGGYGPGPGQSQGGYGQ 79 GG G+G + G G G G G GG G+ +G G G G Sbjct: 3 GGDGRG-HNTGAHSTSGNINGGPTGL--GVGGGASDGSGWSSENNPWGGGSGSGIHWGGG 59 Query: 80 GGYGPGQDQGQGGYGQGGYGQGQGGYEQGGYGAP---VPGYGPP 120 G+G G G G G G G +G P PG G Sbjct: 60 SGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGL 103
>cloacin#Cloacin signature. Length = 551 Score = 44.7 bits (105), Expect = 1e-06 Identities = 29/87 (33%), Positives = 32/87 (36%), Gaps = 7/87 (8%) Query: 625 GGTGRNQAGGAFP-----GGGQTGTFPGGGQGTFPGGGQTGGFPGGGQGGFPGGGQTGGF 679 GG GR GA GG TG GGG G GGG G G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG- 61 Query: 680 PGFPGGTTGGAGGTTGGGTGNGATGSP 706 GG G +GG +G G A +P Sbjct: 62 -HGNGGGNGNSGGGSGTGGNLSAVAAP 87 Score = 43.2 bits (101), Expect = 4e-06 Identities = 27/83 (32%), Positives = 30/83 (36%), Gaps = 10/83 (12%) Query: 620 LNGQPGGTGRNQAGGAFPGGGQTGTFPGGGQGTFPGGGQTGGFPGGGQGGFPGGGQTGGF 679 +NG P G G G GGG G+ G G GG G GGG G Sbjct: 20 INGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Query: 680 P----------GFPGGTTGGAGG 692 GFP +T GAGG Sbjct: 80 NLSAVAAPVAFGFPALSTPGAGG 102 Score = 31.2 bits (70), Expect = 0.019 Identities = 23/92 (25%), Positives = 30/92 (32%), Gaps = 5/92 (5%) Query: 345 GGGAGGRRGFGLLQNGAAAALPGGGTGAGTGTGTGTGAGGAAGLANGAAGGMPFPGGGGP 404 G G G + G GGG G+G + G + GG G GG Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGG 67 Query: 405 GGGRGGGMWGSTGWTRMFGSEVGGQISWLLPA 436 G GGG S V +++ PA Sbjct: 68 NGNSGGGSGTGGN-----LSAVAAPVAFGFPA 94
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 0.001 Identities = 19/104 (18%), Positives = 30/104 (28%) Query: 536 STGLGLAIVAAVVEAHQGRVEATSQPGRTAFVVTLPRWSAAVSAQGEPPNPATVTPGWTA 595 S + A+VA ++ +V P + V + +PP V P Sbjct: 21 SVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEP 80 Query: 596 APGPAPTSPSAPSAPPAPPVPTAPPVPTAPPAPAAPPAQPAPTA 639 P P P + P P P P +P + Sbjct: 81 EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESR 124 Score = 30.7 bits (69), Expect = 0.016 Identities = 19/81 (23%), Positives = 23/81 (28%), Gaps = 7/81 (8%) Query: 573 WSAAVSAQGEPPNPATVTPGWTAA--PGPAPTSPSAPSAPPAP-----PVPTAPPVPTAP 625 V P P +VT A P A P P P P P P Sbjct: 36 SVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE 95 Query: 626 PAPAAPPAQPAPTAGLARPMR 646 P +P P + +P R Sbjct: 96 KPKPKPKPKPKPVKKVEQPKR 116 Score = 29.6 bits (66), Expect = 0.030 Identities = 15/71 (21%), Positives = 17/71 (23%), Gaps = 2/71 (2%) Query: 576 AVSAQGEPPNPATVTPGWTAAPGPAPTSPSAPSA--PPAPPVPTAPPVPTAPPAPAAPPA 633 A PA + P P P P P P PP + P P P Sbjct: 47 AQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPK 106 Query: 634 QPAPTAGLARP 644 R Sbjct: 107 PVKKVEQPKRD 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 112 bits (282), Expect = 1e-29 Identities = 41/166 (24%), Positives = 77/166 (46%), Gaps = 8/166 (4%) Query: 16 MQPVRVLVVDDETTLAELLSMALRYEGWEVRSAGDGRGALRLAREFRPDAVVLDIMLPDM 75 M +LV DD+ + +L+ AL G++VR + R D VV D+++PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 76 DGLEVLRRLRAESPDVPVLFLTARDAVEDRVAGLTAGGDDYVTKPFSLEELVARLRGLM- 134 + ++L R++ PD+PVL ++A++ + G DY+ KPF L EL+ + + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 135 ---RRAARTTEALQGARLVVGD----LTMDEESREVARGGVPVHLT 173 RR ++ + Q +VG + + + + + +T Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.9 bits (70), Expect = 0.011 Identities = 17/61 (27%), Positives = 31/61 (50%) Query: 13 TFVRTLADGLKANLASLDAVTGADTGSSIEVTTVDALAHRIVTEAEGSAPNVLLDEEVLN 72 + + D A LDA+ +D G +++ +DA+ HR+V E +VL+ ++VL Sbjct: 51 KIKKDMKDHKDAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLK 110 Query: 73 G 73 Sbjct: 111 A 111
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 32.9 bits (75), Expect = 8e-04 Identities = 28/135 (20%), Positives = 45/135 (33%), Gaps = 39/135 (28%) Query: 1 MPVTEIDVRTADGVMDVYLHTPDDDGGGTTPPVVIFYPDAGGVRPVMHDMADQFAARGYA 60 + +T + V + V + T PP+VIF GG + + +G+ Sbjct: 29 LGLTLLPVEPSTQV--------NAASSHTKPPLVIFLSGDGGWATLDKAVGGILQQQGWP 80 Query: 61 VAVVN---YFYRSGKISFDVGKVWSDPDLRAELMAVMGKAAPALVVQDTAALLEVLDARS 117 V + Y+ W D P V QDT A+++ A Sbjct: 81 VVGWSSLKYY-------------WKQKD-------------PKDVTQDTLAIIDKYQAEF 114 Query: 118 DVRADKVATVGYCRG 132 + KV +GY G Sbjct: 115 GTQ--KVILIGYSFG 127
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 46.7 bits (111), Expect = 2e-07 Identities = 28/78 (35%), Positives = 41/78 (52%), Gaps = 10/78 (12%) Query: 80 RAVVTVPASYDPAGPLRRVMISAAEAAGFVDVDLLAEPVAAAWSPLVGT---EPEPGSLM 136 R +V VP RR + +A+ AG +V L+ EP+AAA +G E M Sbjct: 109 RVLVCVPVGATQVE--RRAIRESAQGAGAREVFLIEEPMAAA----IGAGLPVSEATGSM 162 Query: 137 LVYDLGGGTFEGALVSVG 154 +V D+GGGT E A++S+ Sbjct: 163 VV-DIGGGTTEVAVISLN 179
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.4 bits (105), Expect = 2e-07 Identities = 19/111 (17%), Positives = 39/111 (35%), Gaps = 4/111 (3%) Query: 9 SVAIIDDHPIATESLAARFAGAGFSVLAPAPSLEAFD--RDAAPGVVVCDLHLPGISGAA 66 ++ + DD L + AG+ V + + + +VV D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 AVADLHAR--GLPVLTTSGVATPDEVLDAIAAQARGFVDKTAPAQQFVAAV 115 + + LPVL S T + A A ++ K + + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>PF07675#Cleaved Adhesin Length = 1358 Score = 29.3 bits (65), Expect = 0.041 Identities = 28/106 (26%), Positives = 40/106 (37%), Gaps = 9/106 (8%) Query: 310 VRHAGGVDEVSLFVEGDADAVLVVVRDRGVGFDPATVRPGGGLSGSYQALRRHGGQALVT 369 V +A GV V++ + + VV R + P + G YQ + +T Sbjct: 288 VANASGVATVNMTKQITENGNYDVVITRS-NYLPVIKQIQAGEPSPYQPVSN------LT 340 Query: 370 ARPGDGVKVTLRWPAPSTP-PDGTTPPDGTTPSDGTTPSDAPDGEA 414 A G KVTL+W APS +G+ T A D A Sbjct: 341 ATA-QGQKVTLKWDAPSAKKAEGSREVKRIGDGLFVTIEPANDVRA 385
>PERTACTIN#Pertactin signature. Length = 922 Score = 35.1 bits (80), Expect = 4e-05 Identities = 25/63 (39%), Positives = 25/63 (39%), Gaps = 1/63 (1%) Query: 48 LPPPGPGPLPTPPDPVPPTPVPDPVPPGPGPDPVPPGPGPDPVPPGPGPDPVPPGPGPDP 107 L G G PP P P P PGP P P PP P P PP P P P P Sbjct: 552 LAANGNGQWSLVGAKAPPAPKPAP-QPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAP 610 Query: 108 VPP 110 PP Sbjct: 611 QPP 613 Score = 34.7 bits (79), Expect = 6e-05 Identities = 25/62 (40%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 32 IPAPGSGQGAEGGSAVLPPPGPGPLPTP-PDPVPPTPVPDPVPPGPGPDPVPPGPGPDPV 90 + A G+GQ + G+ P P P P P P P P PP P P PP P P P P Sbjct: 552 LAANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQ 611 Query: 91 PP 92 PP Sbjct: 612 PP 613 Score = 33.5 bits (76), Expect = 1e-04 Identities = 23/54 (42%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 68 VPDPVPPGPGPDPVPPGPGPDPVPPGPGPDPVPPGPGPDPVPPGPGLDPQPGPG 121 V PP P P P PGP P P PP P P PP P P PQP G Sbjct: 563 VGAKAPPAPKPAP-QPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAG 615 Score = 32.8 bits (74), Expect = 2e-04 Identities = 21/61 (34%), Positives = 22/61 (36%) Query: 41 AEGGSAVLPPPGPGPLPTPPDPVPPTPVPDPVPPGPGPDPVPPGPGPDPVPPGPGPDPVP 100 A G+ G P P P P P P PP P P PP P P P P P Sbjct: 553 AANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP 612 Query: 101 P 101 P Sbjct: 613 P 613 Score = 32.8 bits (74), Expect = 3e-04 Identities = 20/57 (35%), Positives = 21/57 (36%) Query: 38 GQGAEGGSAVLPPPGPGPLPTPPDPVPPTPVPDPVPPGPGPDPVPPGPGPDPVPPGP 94 G G PP P P P P P P P PP P P PP P+ P P Sbjct: 556 GNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQP 612 Score = 31.2 bits (70), Expect = 0.001 Identities = 18/46 (39%), Positives = 18/46 (39%) Query: 80 PVPPGPGPDPVPPGPGPDPVPPGPGPDPVPPGPGLDPQPGPGPVPP 125 P P P P P P P PP P P PP P P P PP Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 7e-05 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 245 EDAPMDLSVTDNPARFRYEAITPAGEIAGFVQYQKRPDRIVFI-HTEVSPEFSGQGVGST 303 ED MD+S + + + G ++ + + I V+ ++ +GVG+ Sbjct: 51 EDDDMDVSYVEEEGKAAFLYYLE-NNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTA 109 Query: 304 LATAALDDVRRQGLA 318 L A++ + Sbjct: 110 LLHKAIEWAKENHFC 124
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 45.2 bits (107), Expect = 2e-07 Identities = 35/155 (22%), Positives = 51/155 (32%), Gaps = 24/155 (15%) Query: 3 EYLADGRALAAVAVGNNGEGDSDLGEAQIQVPSDCVNALGVGAADSVREGWQRASYSAFG 62 + + L A GN G+GD ++ P + VGA + + +S Sbjct: 162 KKAVASQILVMCAAGNEGDGDDRT--DELGYPGCYNEVISVGAINF---DRHASEFSNSN 216 Query: 63 PGRSPGRVKPDLLHFGGEDREPFMVYATDRSPQIASTCGTSFAAP-----AALRLASGIR 117 DL+ G + + +T + A+ GTS A P AL + Sbjct: 217 NE-------VDLVAPGED------ILSTVPGGKYATFSGTSMATPHVAGALAL-IKQLAN 262 Query: 118 AHFGSRLNPLALKALLIHGADGAMNDRSEVGWGRL 152 A F L L A LI N G G L Sbjct: 263 ASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLL 297
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 50.6 bits (121), Expect = 1e-09 Identities = 34/161 (21%), Positives = 57/161 (35%), Gaps = 29/161 (18%) Query: 2 LLADDAELIRASVAVLLRDHGFDVAAQVGDAVSLLAAVGSVRPDIAVVDVRMPPTGTTEG 61 L+ADD IR + L G+DV +A +L + + D+ V DV MP Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN---A 62 Query: 62 LQAAVEIRRTHPGTAVLMLSQYLESDYLDAVFGDDPRSVGYLLKERVSSMGFVGAVRRVA 121 I++ P VL++S + ++ A+ + + YL K Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQ--NTFMTAIKASEKGAYDYLPK---------------- 104 Query: 122 RGGHVVDPAIVDLLMRARRRELGSLSRREREVLALMAEGRS 162 P + L+ R L RR ++ +G Sbjct: 105 -------PFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMP 138
>PF06580#Sensor histidine kinase Length = 349 Score = 40.6 bits (95), Expect = 1e-05 Identities = 17/85 (20%), Positives = 36/85 (42%), Gaps = 10/85 (11%) Query: 496 NTLKHA---QATGVWITVGYSC--GALRVEIADDGVGGAGSGSGSGSGSGLLGLRDRVAA 550 N +KH G I + + G + +E+ + G + + +G+GL +R+R+ Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN-TKESTGTGLQNVRERLQM 324 Query: 551 L---DGTLTVRSEPGAGTRIAAVIP 572 L + + + + G +IP Sbjct: 325 LYGTEAQIKLSEKQG-KVNAMVLIP 348
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 26.1 bits (57), Expect = 0.042 Identities = 9/26 (34%), Positives = 16/26 (61%) Query: 85 VAKLPPVLAELLLNLLTLLLLLLLSH 110 ++KLPP+ ++ +L LL+LL Sbjct: 3 ISKLPPLSPSVIRRILFYLLMLLFCQ 28
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.5 bits (60), Expect = 0.024 Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 70 EKAAAEIAAHGAHLANAAGLRAQSATVQAAPTWKGIIATAAERQADLIVLGAHRHSRLAG 129 E+AAAE A A ++A A P ++ATAA R + GA ++ Sbjct: 224 EQAAAE-AKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAIS 282 Query: 130 HLLGSVATSVVAHAPGAVLV 149 + +V V+A AP + V Sbjct: 283 DAI-AVLGRVLASAPSVMAV 301
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 52.2 bits (125), Expect = 3e-09 Identities = 63/350 (18%), Positives = 123/350 (35%), Gaps = 20/350 (5%) Query: 61 YALGTVLAVQLGLHLPQRRMLLVYAVVLVVGSVLTAAAQD-AAMFIIGHLLQGLATSMLL 119 +++GT + +L L +R+LL ++ GSV+ ++ I+ +QG + Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 120 IAAAPALAIGYPREKLRTTVMIMNMGIFGAVALGPFIGGLQADANAWRPLFWIVTGVSVL 179 +A P+E ++ + +GP IGG+ A W L I + Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIIT 181 Query: 180 ALLLVVLTFEDAPPANPDAPRDLPAIALSAVGSLAAFLGASELTSHSFLDVEVIAPLLGG 239 L+ L D+ I L +VG + L + S SFL V V++ Sbjct: 182 VPFLMKLL---KKEVRIKGHFDIKGIILMSVGIVFFMLFTT-SYSISFLIVSVLS----- 232 Query: 240 LALIVVLVVYQYRATQPLLMVREMLTSSIPVAGVVIALFAAAASVSATGLTASVLAETYG 299 ++ V + + T P + + + + GV+ + ++ + + Sbjct: 233 ---FLIFVKHIRKVTDPFVDP-GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288 Query: 300 --PVRVGLLYL-PELGGAVIAAVTFGFVVTRRSVHYMPLVGMVLLAAGILVFWFAMPASQ 356 +G + + P +I G +V RR Y+ +G+ L+ L F + + Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTS 348 Query: 357 PLALVASGLTGLALGATVAPALFVAGFSLPSANLQRVFALVELLRAVAAF 406 + LG ++ S Q A + LL + Sbjct: 349 WFMTIIIVFV---LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFL 395
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 41.7 bits (98), Expect = 8e-06 Identities = 34/185 (18%), Positives = 62/185 (33%), Gaps = 19/185 (10%) Query: 322 SSMEAAARSYRLGVRE---NPWGQHELRGRLRDAEETLNAAVLGQQQAVGRAVDILVRS- 377 ++ A ++ G + P+ EL G + A + + ++ RS Sbjct: 85 NTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSA 144 Query: 378 VMGLSGAQASSVVRPRGVLFLAGPTGVGKTELAKAISQLVFGEADAYIRFDMSEFAAEHS 437 M + +++ L + G +G GK +A+A+ ++ +M+ + Sbjct: 145 AMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLI 204 Query: 438 ADRLTGAPPGYVGYDAGGELTNAVRQSP--FSL-----LLFDEIEKAAPRILDKFLQVLD 490 L G G T A +S F L DEI + L+VL Sbjct: 205 ESELFGH--------EKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 491 DGRLT 495 G T Sbjct: 257 QGEYT 261
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.5 bits (68), Expect = 0.011 Identities = 14/28 (50%), Positives = 17/28 (60%), Gaps = 2/28 (7%) Query: 292 PDLDDDPDAEPD--GEPDAGPEEPDDPD 317 PD D +PDA PD G+P P+ P PD Sbjct: 355 PDPDLNPDANPDTDGQPGTRPDSPAVPD 382 Score = 29.3 bits (65), Expect = 0.024 Identities = 18/45 (40%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 274 NEDVGRRRYRPPRDVQDLPDLDDDPDAEPDGEPDAGPEEPDDPDG 318 NE+ G R P D PD + D D +P PD+ P PD P+G Sbjct: 344 NENPGTRP-NPEPDPDLNPDANPDTDGQPGTRPDS-PAVPDRPNG 386 Score = 28.9 bits (64), Expect = 0.033 Identities = 12/31 (38%), Positives = 15/31 (48%) Query: 292 PDLDDDPDAEPDGEPDAGPEEPDDPDGSAQP 322 P+ + DPD PD PD + PD A P Sbjct: 351 PNPEPDPDLNPDANPDTDGQPGTRPDSPAVP 381
>cloacin#Cloacin signature. Length = 551 Score = 26.2 bits (57), Expect = 0.040 Identities = 12/33 (36%), Positives = 16/33 (48%) Query: 79 AGGGSGRPGGGRGRPGGGVGRAGGGAYGAGGGT 111 +G G GG GGG G +GGG+ G + Sbjct: 50 SGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLS 82
>cloacin#Cloacin signature. Length = 551 Score = 29.3 bits (65), Expect = 0.020 Identities = 18/64 (28%), Positives = 24/64 (37%) Query: 102 ASDPAAGDKAGGPAGDAAGGGPAGDAASGGPAGDTTGGTGDTAGSPGGASVGGGPRPVDA 161 ASD + P G +G G SG G G +G +G+ G S P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGF 92 Query: 162 PAPA 165 PA + Sbjct: 93 PALS 96
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.9 bits (85), Expect = 5e-04 Identities = 22/100 (22%), Positives = 29/100 (29%) Query: 616 APPRPPAPSPAPAPSPPPAPAPPPAPAASAPSAPSPPLGPAPSSISLEDSPSLVESPSPA 675 A PP P P P P P P PP P +++ P P + Sbjct: 60 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVES 119 Query: 676 GSPSPADPIRPGRGGDAVAAALLDEVGGSHPRAEELARRA 715 SP + P R + A A + S R Sbjct: 120 RPASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRN 159
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 38.9 bits (90), Expect = 2e-06 Identities = 18/78 (23%), Positives = 32/78 (41%), Gaps = 5/78 (6%) Query: 52 GDFQEWTVGTTEFATAVTFRDAATGRCLDSDAARR----VYTLACNVGSY-QKWQVTRND 106 G+ + W + + FR+ G C+ S + + T C G +Q Sbjct: 113 GELRNWQIMPGTRPNTIQFRNVDVGTCMTSFPGFKGGVQLSTAPCKFGPERFDFQPMATR 172 Query: 107 YGTYSFRNLATGFCLDSN 124 G Y ++L+TG C+ +N Sbjct: 173 NGNYQLKSLSTGLCIRAN 190
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 71.6 bits (175), Expect = 2e-17 Identities = 43/211 (20%), Positives = 74/211 (35%), Gaps = 9/211 (4%) Query: 12 RQRRADGDRTRAAILDAAVRLSTVDGLEGLSIGNLAKDLGMSKGGVYAHFDSKQDLQLAT 71 R+ + + TR ILD A+RL + G+ S+G +AK G+++G +Y HF K DL Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 72 VEAAGVIFRSEVIE-PALTADPGVPQLLAFCDGFFD---HLERRVFPGGCFFAGAALEMG 127 E + +E A + L + ERR F E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKC--EFV 120 Query: 128 THRGPVQEKVAEFHSGFVQLIRDVVRTAVQLRQLPPDEDPAALALELNGTLLAADTSFVM 187 VQ+ I ++ ++ + LP D A+ + G + +++ Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 188 YDD-PSVLDLGRRVVRRRLGLAVTRRDETPE 217 + R V + L + T Sbjct: 181 APQSFDLKKEARDYV--AILLEMYLLCPTLR 209
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 35.7 bits (82), Expect = 1e-04 Identities = 20/78 (25%), Positives = 30/78 (38%), Gaps = 5/78 (6%) Query: 60 GKFKDFKDGKDGKDSKDGKEGKDS---KEWKDVKDGKDGKDRKDGKEFKDT--KDYGKDT 114 KF D G DG D +G +G D + D G +G D+ G + D G + Sbjct: 734 SKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNY 793 Query: 115 KDTKDGKDRWDRADPGVG 132 + DG D + + Sbjct: 794 LNGGDGDDEFQVQGNSLA 811
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 30.9 bits (70), Expect = 0.010 Identities = 28/164 (17%), Positives = 54/164 (32%), Gaps = 43/164 (26%) Query: 27 QIEREIARWEAARLVVRARFARL--RPPELDGGEQR--YQAFDEFAGD-ELAAELRLSPA 81 + EI + AA + + + G ++ + A D EL ++ Sbjct: 36 DVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAAHLLVLDDPELVDGIKGKIE 95 Query: 82 AGGRRLAFAVSAVRRMPAAVNALGFGSID----LERLSALE----RLTANLTDEQ----- 128 +A+ V M ++ F S+D ER + + R+ +L + Sbjct: 96 NEQMNAEYALKEVSDMFVSM----FESMDNEYMKERAADIRDVSKRVLGHLIGVETGSLA 151 Query: 129 ---------ADEV------------AGGVLSNGGGRPSHSAFAA 151 A+++ G ++ GGR SHSA + Sbjct: 152 TIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMS 195
>cloacin#Cloacin signature. Length = 551 Score = 33.1 bits (75), Expect = 0.002 Identities = 27/94 (28%), Positives = 36/94 (38%), Gaps = 4/94 (4%) Query: 6 GSLVGDGDGDGDTTFLGPFGARGGATGPAGGARDTPTGPGPGPGPGPGPGPGPGPGPGPG 65 G+ G+ +G T LG G G + G + + P G G G G G G G G G G G Sbjct: 12 GAHSTSGNINGGPTGLGVGG--GASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 66 P--GVSSAAGTVTPDVGAFDAARAAGAARGGGAP 97 G S G ++ A + G G Sbjct: 70 NSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGL 103
>PERTACTIN#Pertactin signature. Length = 922 Score = 29.7 bits (66), Expect = 0.003 Identities = 24/68 (35%), Positives = 28/68 (41%), Gaps = 5/68 (7%) Query: 13 RTPPRTPPPTGTTPQSGTTPPSRTTPPPGTTPPSRTPPSRRTPPPPRTGPPPPPSSRLAQ 72 + PP P PQ G PP PP PP P +R P P P PP L+ Sbjct: 566 KAPPAPKPAPQPGPQPGPQPPQ---PPQPPQPPQPPQPPQRQPEAP--APQPPAGRELSA 620 Query: 73 RAVAALLT 80 A AA+ T Sbjct: 621 AANAAVNT 628
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.1 bits (166), Expect = 2e-16 Identities = 37/149 (24%), Positives = 63/149 (42%), Gaps = 11/149 (7%) Query: 1 MPRNRQEVPREERIDALLAVAEEQFLARGFAGTSIAEIARSAGIEPGSVYWYFRSKDHAF 60 M R ++ +E R +L VA F +G + TS+ EIA++AG+ G++YW+F+ K F Sbjct: 1 MARKTKQEAQETR-QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 AAVLN----RLLDVEVERIAGLPGNPADKL------FLALDSVERRRTLHPCVAERAPHA 110 + + + ++E+E A PG+P L L E RR L + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 111 EPVMEYHERLHAWLHGLSLAAVHDYVPEA 139 M ++ L S + + Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHC 148
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 30.7 bits (69), Expect = 0.035 Identities = 14/47 (29%), Positives = 23/47 (48%), Gaps = 1/47 (2%) Query: 485 DWESLRAEVSAAGTGVDGVVGTGSRAVAARAAGLAAAGAGGGQAGAP 531 D +SL A +D + T S +A+ ++G++AA GAP Sbjct: 349 DGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAAT-TSLVGAP 394
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 3e-04 Identities = 22/60 (36%), Positives = 24/60 (40%), Gaps = 6/60 (10%) Query: 10 PAPAGPVQSEPTVQSEPTVQSEPTVQSEPAAEPEPAAEPEPAAEPEPAAEPEPPVLAEPS 69 PAPA P+ P P P PEP EPEP EP P E PV+ E Sbjct: 44 PAPAQPISVTMV---APADLEPPQAVQPP---PEPVVEPEPEPEPIPEPPKEAPVVIEKP 97
>cloacin#Cloacin signature. Length = 551 Score = 28.5 bits (63), Expect = 0.036 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 5/81 (6%) Query: 12 GKGGNGRNVPTATRSAGRSAASSAAGSEGGASSGDAVSS-----GGAVSSEGSAGARGGA 66 G G G N + S + + G GGAS G SS GG S G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 67 GTRAAAGPSSAGAAGGGSGPA 87 G G S G+ GG+ A Sbjct: 63 GNGGGNGNSGGGSGTGGNLSA 83
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 34.7 bits (79), Expect = 0.002 Identities = 23/61 (37%), Positives = 28/61 (45%), Gaps = 7/61 (11%) Query: 267 VPPPGPGRSPAEVAAPSRLPGTRPAGPP-----PPARPGPPTPPPSPPPSPPLSAPGRPG 321 +P P +PA AP+ PGTRP P P A P P + P SP + P RP Sbjct: 328 LPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSP--AVPDRPN 385 Query: 322 G 322 G Sbjct: 386 G 386
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 37.0 bits (85), Expect = 7e-04 Identities = 28/119 (23%), Positives = 46/119 (38%), Gaps = 5/119 (4%) Query: 2624 ATLQSLASSVRYHAVDVRDGAAVAAVVADVYARHGRLDGLVHGAGVLADRLLRDKTPESF 2683 ++L++ A DVRD AA+ + A + G +D LV+ AGVL L+ + E + Sbjct: 50 SSLKAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEW 109 Query: 2684 DRVYRTKVDGARALLAAV-----RDDVGFVALFGSVAGVFGNRGQADYAAANDALDTLA 2737 + + G +V G + GS A YA++ A Sbjct: 110 EATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.5 bits (66), Expect = 0.042 Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 8/72 (11%) Query: 16 SPAWWRRGRAGTGLTAVLDWLPVLVCVGLLINGVRLRGRL-RRLETVPASGRPVDPSHEF 74 ++ + L A WL VLV +L +R +L RR+E A+ E Sbjct: 451 QQSFIDQ------LLAAGRWLLVLVVAWILWRKA-VRPQLTRRVEEAKAAQEQAQVRQET 503 Query: 75 LVADGVQLTDSG 86 A V+L+ Sbjct: 504 EEAVEVRLSKDE 515
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 166 bits (421), Expect = 9e-51 Identities = 86/368 (23%), Positives = 133/368 (36%), Gaps = 68/368 (18%) Query: 1 MRVLVTGGAGFIGSHIVDAAVAAGDEVRILDALLPAV------HRVAPAVNGGAELVVGN 54 M+ LVTG AGFIG H+ + AG +V +D L R+ G + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 55 VTDRGQVEAALD--GIDVVYHEAAMVGLGVDLDDLPAYAANNDLGTAVLLAAMARAGIGR 112 + DR + + V+ + + L++ AYA +N G +L I Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 113 LVLASSMVVYGEGGYRCAEHAAVRPGPRVRADLDAGRFEPPCPHCHRQLASVPVREDAPI 172 L+ ASS VYG +P D + Sbjct: 121 LLYASSSSVYGLN------------------------------------RKMPFSTDDSV 144 Query: 173 D-PRNVYAATKVAQEHLAAAWAAATGGTVIALRYHNVYGPRMPRDTPYAGVASIFRSALA 231 D P ++YAATK A E +A ++ G LR+ VYGP D F A+ Sbjct: 145 DHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMAL----FKFTKAML 200 Query: 232 AGRAPRVFEDGGQLRDFVHVHDVAHANLLAARRPDR-----------------PGRLTAL 274 G++ V+ G RDF ++ D+A A + P R+ Sbjct: 201 EGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRV--Y 258 Query: 275 NIGSGTPRTVGDMADALARAVGGPSPVVTGGYRIGDVRHIVASSVGAAELLGYRARVGFA 334 NIG+ +P + D AL A+G + + GDV A + E++G+ Sbjct: 259 NIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVK 318 Query: 335 AGMAAFAR 342 G+ F Sbjct: 319 DGVKNFVN 326
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 97.2 bits (242), Expect = 2e-25 Identities = 44/150 (29%), Positives = 70/150 (46%), Gaps = 1/150 (0%) Query: 2 ARVLVVDDDALVAEVVDRYLRNAGFDVDRAADGPSALRTAEARPPDLVVLDLMLPGLDGL 61 A +LV DDDA + V+++ L AG+DV ++ + R A DLVV D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVFRRLTARRP-VPVIMLTARADEADRITGLEVGADDYVTKPFSPRELTLRVRSVLRRAA 120 ++ R+ RP +PV++++A+ I E GA DY+ KPF EL + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 EAAAAPEPGVLRAGALVVDPAARTATRHEV 150 + E LV AA + Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVL 153
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.5 bits (61), Expect = 0.002 Identities = 9/31 (29%), Positives = 19/31 (61%) Query: 9 TEAAELLGVSRSTVYELMNSGDIESVRIGRA 39 +AA+LLG++R+T+ + + + R R+ Sbjct: 453 IKAADLLGLNRNTLRKKIRELGVSVYRSSRS 483
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 2e-14 Identities = 22/111 (19%), Positives = 39/111 (35%), Gaps = 2/111 (1%) Query: 1 MVDDHELFLQGLQTVLEIEEDISVVGRAGDGQEALTLASGTSPDIVLMDVRMPGRDGIAA 60 + DD L L V + + D+V+ DV MP + Sbjct: 8 VADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 61 AGAIKRAVPRTRIVMLTVSDEESDLFEAIKAGAVGYLLKSIPPHEVADAVR 111 IK+A P +++++ + +A + GA YL K E+ + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 54.8 bits (132), Expect = 1e-10 Identities = 38/128 (29%), Positives = 54/128 (42%), Gaps = 9/128 (7%) Query: 125 GVVPIVNENDAVATQEIRFGDNDRLAAIVAHLVSADLLVLLSDVDGLYDANPRHGPANLL 184 G VP++ E+ + E D D +A V+AD+ ++L+DV+G L Sbjct: 195 GGVPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTDVNGAA-LYYGTEKEQWL 252 Query: 185 REVRSDADLAGLTARGTGTAGVGVGGMATKIEAA-RMAASGGVTAIITSAANAAPVLRGE 243 REV+ + +L G G M K+ AA R GG AII A L G Sbjct: 253 REVKVE-ELRKYYEEG----HFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVEALEG- 306 Query: 244 EVGTVFHP 251 + GT P Sbjct: 307 KTGTQVLP 314
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.0 bits (85), Expect = 5e-04 Identities = 43/303 (14%), Positives = 78/303 (25%), Gaps = 30/303 (9%) Query: 587 TQIRTL---HAELAREPSDSVEPPVPPVPPVPPVPPVPPGAGADEPPDPLSQVRRFQVVE 643 T I T A++ PS++ E PVPP P P + + Q + Sbjct: 995 TNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN 1054 Query: 644 LLDDRAPASAHRLAELAARVDDLVAARTRAAADL-------TPAEAATLAVYEEEKDAAA 696 D + +R A+ + +T A E A E+E+ A Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 697 RLAAARSSEQAARLRAAQMRRLAATRLTAVPADLRDAEALAARLNAVTTLAADQEATHEA 756 + + + + + + A PA D + T AD E + Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 757 ELAAERARAEHVRAGLTALDLVRQAGFVDLDDAAAAVRDEPWRRTAEQEVLEYREETAAV 816 + T +V V E ++ + +R +V Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSE----SSNKPKNRHRRSVRSV 1230 Query: 817 AAALAGDDLAVDPDITVPLAEHAAAAEEARQAHESAVATLARASGRAAELAALHTTFTAD 876 E A + R T + ++ A + Sbjct: 1231 PHN----------------VEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALN 1274 Query: 877 LTA 879 + Sbjct: 1275 VGK 1277
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 33.6 bits (77), Expect = 2e-04 Identities = 18/72 (25%), Positives = 27/72 (37%), Gaps = 5/72 (6%) Query: 4 GVMGGTFDPVHNGHLVAASEVAALFDLDEVVFVPSGQPWQKVHRVVSDPEDRYLMTFLAT 63 + G+FDP+ GHL LF D+V P ++ + ++R A Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLF--DQVYVAVLRNPNKQ---PMFSVQERLEQIAKAI 57 Query: 64 AENPQFTVSRVE 75 A P V E Sbjct: 58 AHLPNAQVDSFE 69
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 176 bits (449), Expect = 4e-55 Identities = 77/343 (22%), Positives = 129/343 (37%), Gaps = 49/343 (14%) Query: 4 MRVVVAGGAGFLGSHLCERLLAGGAEVICVDNFLTGRPENVDPLRAL----DGFRMLRRD 59 M+ +V G AGF+G H+ +RLL G +V+ +DN ++ R GF+ + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 60 VTGPVDVA-----GPVDTVVHLA-------SPASPVDYRALPLETLAVGAWGTRRLLELA 107 + + G + V S +P Y L G +LE Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLT-------GFLNILEGC 113 Query: 108 RRKG-ARFVLASTSEVYGDPQVHPQPEGYWGHVNPVGPRSMYDEAKRFAEALTTAHRATH 166 R + AS+S VYG + P + P S+Y K+ E + + + Sbjct: 114 RHNKIQHLLYASSSSVYGLNRKMPFST----DDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 167 GTRTGIVRIFNTYGPRMRADDGRVVPTFITQALRGRPVTVAGDGSQTRSLCYVDDLVDGL 226 G +R F YGP R D + F L G+ + V G R Y+DD+ + + Sbjct: 170 GLPATGLRFFTVYGPWGRPD--MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 227 VRMLDA----------EHPGP---------VNLGSPRELSVLELARLVVGLCGEQVPIVF 267 +R+ D E P N+G+ + +++ + + G + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 268 VPRPPDDPSVRRPDVTLADEVLDWRPAVDLADGLARTVGWFRE 310 +P P D D EV+ + P + DG+ V W+R+ Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 35.1 bits (80), Expect = 0.001 Identities = 22/57 (38%), Positives = 23/57 (40%), Gaps = 11/57 (19%) Query: 576 PGQESESGAQPLPE----------PVPMPVPSAGANPEDPTATHSPTAGQDTDTSPG 622 PG AQPLPE P P P NPE P +P A DTD PG Sbjct: 317 PGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPE-PDPDLNPDANPDTDGQPG 372
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.3 bits (73), Expect = 0.005 Identities = 18/103 (17%), Positives = 27/103 (26%), Gaps = 5/103 (4%) Query: 336 RAGTPDPAVPA-----AAGAAAAPPVRRDPATAAAAATTAPIGPPDSPPPTGIALPRAAP 390 P PA P A P + P P P+ P + + + P Sbjct: 40 VIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKP 99 Query: 391 PAVDAPVAATPAPAAGPDHAAALPAPAGALASRSPTGPATAVA 433 P D PA + +P P ++ A Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTA 142
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 2e-05 Identities = 16/84 (19%), Positives = 30/84 (35%), Gaps = 11/84 (13%) Query: 7 NAVRH-----TRSGRIRVRVGPAADLVRIEVVNEGVGFVVPV---AGRGLVGMRKRARL- 57 N ++H + G+I ++ V +EV N G + G GL +R+R ++ Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQML 325 Query: 58 --EGGSFDAGPVGGGFRVLATLPA 79 G + +P Sbjct: 326 YGTEAQIKLSEKQGKVNAMVLIPG 349
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 30.9 bits (69), Expect = 0.016 Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 2/29 (6%) Query: 120 AGVVHRDLKPGNVML--AEDGAKVIDFGI 146 AGVVH D+KPGNV+ A VID G+ Sbjct: 264 AGVVHNDIKPGNVVFDRASGEPVVIDLGL 292
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 35.9 bits (82), Expect = 0.001 Identities = 30/96 (31%), Positives = 44/96 (45%), Gaps = 10/96 (10%) Query: 121 LAAGLAEALTAIHGAGIVHRDLKPGNVIL---SGDGPKVIDFGIAAAVDATVATRTGVLL 177 +A L + + AG+VH D+KPGNV+ SG+ P VID G+ + T Sbjct: 250 IAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGE-PVVIDLGLHSRSGEQPKGFT---- 304 Query: 178 GSPGYMAPEQVTGHGEVGPAADVFAWGLTVLYAATG 213 + APE G+ +DVF T+L+ G Sbjct: 305 --ESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.7 bits (113), Expect = 4e-09 Identities = 24/132 (18%), Positives = 46/132 (34%), Gaps = 4/132 (3%) Query: 7 DARVRLQEAALALYGERGYEETTVAEIAQRAGLTKRTFFRYFADKREVLFWGSELLEQQM 66 + R + + AL L+ ++G T++ EIA+ AG+T+ + +F DK ++ EL E + Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 67 VAAIEAAPAPVSLLRLIAAALEAAAVRFEEVREFAGPRHRIIAA--SPELRERELIKAAS 124 A + L + E R ++ E+ Sbjct: 71 GELELEYQAK--FPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 125 LAAAMAQALRAR 136 + R Sbjct: 129 AQRNLCLESYDR 140
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.013 Identities = 22/65 (33%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 48 DIFGDKGNRDGKDGRDGRDGFDNRDGFDNRDGGDKQRRADNLDGNRDGRDGRDGKDDRDG 107 DIF D +G DG D G D GG+ + DGN D G G + +G Sbjct: 738 DIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGN-DKLIGVAGNNYLNG 796 Query: 108 RDGRD 112 DG D Sbjct: 797 GDGDD 801 Score = 28.4 bits (63), Expect = 0.021 Identities = 22/73 (30%), Positives = 27/73 (36%), Gaps = 1/73 (1%) Query: 48 DIFGDKGNRDGKDGRDGRDGFDNRDGFDNRDGGDKQRRADNLDGNRDGRDGRDGKDDRDG 107 D F D G DG D + DG D G +G+ D G DG D G Sbjct: 729 DKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGD-DQLYGGDGNDKLIG 787 Query: 108 RDGRDGRDGKDDD 120 G + +G D D Sbjct: 788 VAGNNYLNGGDGD 800
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 29.6 bits (66), Expect = 0.026 Identities = 20/54 (37%), Positives = 21/54 (38%), Gaps = 1/54 (1%) Query: 263 GAPAGPAPAAPATGGKPAAPPSSAPLGSAPLGSVPPGAAIGPTRTAAVAPAGGG 316 GA A PAP PA P P P AP P G + AAV G G Sbjct: 568 GAKAPPAPK-PAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVG 620
>INTIMIN#Intimin signature. Length = 939 Score = 36.6 bits (84), Expect = 1e-04 Identities = 14/63 (22%), Positives = 28/63 (44%) Query: 121 VSISADKSTVAPNTPVVLTVRATEADTGAPLSGQDVRIVVVNGPQWQTSTRLHTDANGTA 180 +ADK++ + +T AT G + V +V+G ++ +T+ +G A Sbjct: 561 TDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKA 620 Query: 181 QIT 183 +T Sbjct: 621 TVT 623 Score = 35.0 bits (80), Expect = 5e-04 Identities = 24/128 (18%), Positives = 44/128 (34%), Gaps = 13/128 (10%) Query: 119 TNVSISADKSTVAPNTPVVLTVRATEADTGAPLSGQDVRIVVVNGPQWQTSTRLHTDANG 178 + I ADK+T N +T P+S Q+V G +++ TD NG Sbjct: 659 SITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGK--LSNSTEKTDTNG 716 Query: 179 --TAQITARLLSTTTITAVFDGSSALRPSLAGAATVTIASPVRGAGGLGGFGSGSGSGSV 236 +T+ + ++A + + + G + G+G Sbjct: 717 YAKVTLTSTTPGKSLVSARVSDVAV---DVKAPEVEFFTTLTIDDGNIEIVGTG------ 767 Query: 237 IDQAIPTV 244 + +PTV Sbjct: 768 VKGKLPTV 775
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 41.5 bits (97), Expect = 2e-06 Identities = 58/266 (21%), Positives = 103/266 (38%), Gaps = 14/266 (5%) Query: 13 SVELVPVRRGSLAWAVIDAWVMARRNLVQTWRIPELTVFATV-QPVLFVLLFTYVFGGAI 71 SV +P GSL W + W RRN + + ++ + +P++++ G + Sbjct: 5 SVTALPG--GSLNWIAV--W---RRNYIAWKKAALASLLGHLAEPLIYLFGLGAGLGVMV 57 Query: 72 NVGGGLDYVDYLMPGVFTQTVIFGAMVTGL--GLAEDRQRGLMDRFRSLPMTRSALLTGR 129 GG+ Y +L G+ + + A + + + + ++ G Sbjct: 58 GRVGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGE 117 Query: 130 TLSDLLRNAFIIVVMLAVGLAVGFRFGDTTVPAVLAGFGLILLFSYAFCWLSAVIGLSVR 189 + A + V A+G+ T ++L +I L AF L V+ Sbjct: 118 MAWAATKAALAGAGIGVVAAALGY----TQWLSLLYALPVIALTGLAFASLGMVVTALAP 173 Query: 190 SAEAAQSGGFVWIFPLVFASSAFAPVATMPGWLQAFARHQPVSVTIDAVRSLFLGGPVSS 249 S + + I P++F S A PV +P Q AR P+S +ID +R + LG PV Sbjct: 174 SYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVD 233 Query: 250 SLLQSLAWCLGLLAVFAPLAVGIHRR 275 A C+ ++ F + RR Sbjct: 234 VCQHVGALCIYIVIPFFLSTALLRRR 259
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 31.3 bits (71), Expect = 0.022 Identities = 10/37 (27%), Positives = 13/37 (35%) Query: 1012 ALAGHRPVAGGTMPNRAVLFDRHTQSEPRTVVPFAPM 1048 GHR V GG +VL + AP+ Sbjct: 85 DAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 7e-04 Identities = 17/69 (24%), Positives = 26/69 (37%), Gaps = 4/69 (5%) Query: 492 RIDVLLRVTSVDVLVEVRDDGCGPGGASRSS---GLANLRRRAQDL-GGRMGFGPGENGI 547 +I + + V +EV + G ++ S GL N+R R Q L G E Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 548 GTTVTWLVP 556 L+P Sbjct: 340 KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 5e-09 Identities = 16/85 (18%), Positives = 34/85 (40%) Query: 5 AGRADEALGQIIALRPKVAVLDARLEDGSGIEVCRQVRSADPGIACLILTSFDDEEALFT 64 A I A + V D + D + ++ +++ A P + L++++ + Sbjct: 33 TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIK 92 Query: 65 AIMAGAAGYVLKQIRGTALVDAVRQ 89 A GA Y+ K T L+ + + Sbjct: 93 ASEKGAYDYLPKPFDLTELIGIIGR 117
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.3 bits (91), Expect = 3e-05 Identities = 49/257 (19%), Positives = 78/257 (30%), Gaps = 33/257 (12%) Query: 148 PGAAGTEVPVGTDELVAP-DGSTPATSTETRTTEVLPSAPTAETPVAETPVAETPTAET- 205 P V T + P + S + E+ A E PV P TP+ T Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI---ARVDEAPVPP-PAPATPSETTE 1038 Query: 206 AVAETAVAETAADAGAAEPAASEPAQVAESAGAAEPDDRAA--AADIAKVVDEAVATDVA 263 VAE + E+ + A AQ E A A+ + +A ++A+ E T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 264 VATDGAVAVDGGEAADAAESAEKAESAEKAEAADSTEKAAQSGGDDPTVVAAAGRKGRKR 323 + A E K E+ + E T + V+ + Sbjct: 1099 ETKE--------TATVEKEEKAKVETEKTQEVPKVTSQ-----------VSPKQEQSETV 1139 Query: 324 RGDAEAPRCGARRGLLRRRPAEVATAAATAAPAATAAP------TSAAAPATSGSPAPTA 377 + AE R ++ ++ T A T PA + T + T S Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199 Query: 378 EIASPADAGTEEGTAGQ 394 E +PA + Sbjct: 1200 ENTTPATTQPTVNSESS 1216 Score = 37.0 bits (85), Expect = 1e-04 Identities = 37/218 (16%), Positives = 62/218 (28%), Gaps = 11/218 (5%) Query: 76 TVALDVTPTAAAVAPTSRGRKAAAEPVASHPVAAAPAEPAPAEPVAASSIEP-----AAV 130 T +V + + T V A E P S + P V Sbjct: 1080 TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 131 EPEAGPAPSGAAAGETVPGAAGTEVPVGTDELVAPDGSTPATSTETRTTEVLPSAPTAET 190 +P+A PA + T T++ S TT ++ E Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVV-EN 1198 Query: 191 PVAETPVAETPTAETAVAETAVAETAADAGAAEPAASEPAQVAESAGAAEPDDRAAAADI 250 P TP PT + + + + P EPA + + + + + Sbjct: 1199 PENTTPATTQPTVNSESSNK-PKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNT 1257 Query: 251 AKVVDEAVATDVAVATDGAVAV----DGGEAADAAESA 284 V+ +A A VA + AV E + + Sbjct: 1258 NAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.017 Identities = 17/37 (45%), Positives = 21/37 (56%) Query: 72 GAVAAAGALSEAVCVPRVGRALDRFGQARVLLAGLAG 108 G + A AL + C P +G DRFG+ VLL LAG Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAG 82
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 74.2 bits (182), Expect = 1e-18 Identities = 49/209 (23%), Positives = 82/209 (39%), Gaps = 17/209 (8%) Query: 1 MSREVLMAAAMEVVDTNGAGAFSMRALGGFLDCDPTAMYRHFATKNALLDALVDSVVRDG 60 ++RE ++ AA+E+++ G + R L L + +Y H K ALLDAL ++ Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 61 VA-DLPESDDPRAD-IRANFRQLRRSLLAHPTLAPLVLRRPPGVGAYWERSDHAVAQLHR 118 LP + + +R N RR+LL + A + L P Y + + + + Sbjct: 64 HDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQY-DTVETQLRFMTE 122 Query: 119 AGMDPADAANVYQTLLFYTLGHTLSEARQLARAVEKEGAGARGGPVAQVRPPAELHPDLS 178 G D + +TLG L + A ++ P E P L Sbjct: 123 NGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPA------------APDENLPPLL 170 Query: 179 DVAPHL--REDNEAQFLAGLDLILRDLPR 205 A + +D E FL GL+ ++R Sbjct: 171 REALQIMDSDDGEQAFLHGLESLIRGFEV 199
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.006 Identities = 14/56 (25%), Positives = 26/56 (46%), Gaps = 12/56 (21%) Query: 83 LSVRPDHQRRGVGHALMHAMLGAAD-ALGEPLVGL--------LGDPGYYSRFGFR 129 ++V D++++GVG AL+H A + A GL + +Y++ F Sbjct: 95 IAVAKDYRKKGVGTALLHK---AIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 28.8 bits (64), Expect = 0.010 Identities = 15/37 (40%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 16 WRD-VETAHPTLADAVRTRFEAFRHHILATIRADGSP 51 WR ++ PTLA AVR R H+L IR D Sbjct: 14 WRTHLQPQDPTLAQAVRATIAKHREHLLEFIRLDEPA 50
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 49.4 bits (118), Expect = 1e-08 Identities = 28/132 (21%), Positives = 52/132 (39%), Gaps = 9/132 (6%) Query: 129 PDESYALRPLAGLMFPRDHYVDLGGAIAVGRLRRRDRARETVVMAAVLRGLRGRSAEVRV 188 + + P+ ++F RD + +G + + ++ + R RET+ + + V + Sbjct: 147 GANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTKVRQRETIFAEYIFKYHPVYKENVPI 206 Query: 189 ----PEPLFLAGGDV-VSCDGVAVLGTGARTSPAAWGLLRPYLLA---AFGRVVRVRDEL 240 E L GGD V G+ V+G RT + L L +F ++ + Sbjct: 207 WLNRWEEASLEGGDELVLNKGLLVIGISERTEAKSVEKLAISLFKNKTSFDTILAFQIPK 266 Query: 241 LRAGEPHLDHWL 252 R+ HLD Sbjct: 267 NRS-YMHLDTVF 277
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 121 bits (305), Expect = 1e-35 Identities = 75/253 (29%), Positives = 123/253 (48%), Gaps = 18/253 (7%) Query: 7 RVAAVVGAASGIGQAIAIALAEQGAVVECADVDTTGVEETVAAIVAAGGTAKASTVDVRV 66 ++A + GAA GIG+A+A LA QGA + D + +E+ V+++ A A+A DVR Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 67 SAEVDDLFARVVADRGRLDIAVGTPGINIRKPLIDYTDDDYTAVTDVNLRGSFHVLRGAG 126 SA +D++ AR+ + G +DI V G+ + +D+++ A VN G F+ R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 127 RIMAKQGGGSIIVISSISSRAVEPGQVIYAGTKAALAQMVRVLAAELGPAGVRVNAIAPG 186 + M + GSI+ + S + YA +KAA + L EL +R N ++PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 187 PVETALTVPIRSSAAWADAYAQK-------------VAVGRWARPAEIAGPAVFLASDAA 233 ET + + WAD + + + + A+P++IA +FL S A Sbjct: 189 STETDM-----QWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 234 TYVNGEVLFVDGG 246 ++ L VDGG Sbjct: 244 GHITMHNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 2e-19 Identities = 44/122 (36%), Positives = 61/122 (50%), Gaps = 4/122 (3%) Query: 24 SGQTILVADDEDAMREIMRRVLTRNGYHVLTAPSAVEACTIAIEHVGEIDLLLTDVIMPR 83 +G TILVADD+ A+R ++ + L+R GY V +A G+ DL++TDV+MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA--GDGDLVVTDVVMPD 59 Query: 84 MQGRELANRIKAGRPAIRVLYMSGYPHPVLTAQGKLEADVY-LLEKPFTGPVLLDKVREV 142 +L RIK RP + VL MS +TA E Y L KPF L+ + Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNT-FMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 143 LD 144 L Sbjct: 119 LA 120
>cloacin#Cloacin signature. Length = 551 Score = 31.2 bits (70), Expect = 0.004 Identities = 21/74 (28%), Positives = 36/74 (48%), Gaps = 5/74 (6%) Query: 177 EDLTKRLSDQASALQTISTVMSRVGDSAARALETVQAMNKEGARI----VARAHQVWNLS 232 ED+ + QA A+Q ++ S + D+A + L A K+ R +A H++W ++ Sbjct: 335 EDVARNQERQAKAVQVYNSRKSEL-DAANKTLADAIAEIKQFNRFAHDPMAGGHRMWQMA 393 Query: 233 NLDVTKKNADVTNK 246 L + DV NK Sbjct: 394 GLKAQRAQTDVNNK 407
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 52.5 bits (126), Expect = 2e-10 Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 1/79 (1%) Query: 15 DTNINGTYTVFEAARRQGVPRVIFASSNHAVGFYPRSKAPAPDYLFPMPDTYYGVSKAAG 74 D+N+ G + E R + +++ASS+ G R + D P + Y +K A Sbjct: 100 DSNLTGFLNILEGCRHNKIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKAN 158 Query: 75 EALGSLYSSRYGMDVICLR 93 E + YS YG+ LR Sbjct: 159 ELMAHTYSHLYGLPATGLR 177
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 28.0 bits (62), Expect = 0.036 Identities = 17/60 (28%), Positives = 30/60 (50%), Gaps = 2/60 (3%) Query: 134 HEFQSSKTEPPLLHFAIEL-DTDDGSYFFDFGWETMFIRGSYTVGEGPKRMIGLQRIPMP 192 + PPLL A+++ D+DDG F G E++ IRG +++G ++ +P Sbjct: 158 RPAAPDENLPPLLREALQIMDSDDGEQAFLHGLESL-IRGFEVQLTALLQIVGGDKLIIP 216
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 2e-04 Identities = 33/163 (20%), Positives = 56/163 (34%), Gaps = 10/163 (6%) Query: 12 RAGTLLISGNALLRDGLARMIESADY-AFVAATVDDGHILPALGEGIANVQVTIVDASGP 70 A L+ +A +R L + + A Y + + + G + + D P Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATL--WRWIAAGD--GDLVVTDVVMP 58 Query: 71 FETDVTRVDQAIAAYPHSRVLVLGRDSNMSTAQAFLRRGASAYLPIATRRDHLLATVWLL 130 E + + A P VLV+ + TA +GA YLP L+ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 131 LNDQDSKVVILPRD-DEGEALPGVREVLSKREMEVIEIVAEAA 172 L + + L D +G L G S E+ ++A Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGR----SAAMQEIYRVLARLM 157
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 26.6 bits (58), Expect = 0.024 Identities = 11/21 (52%), Positives = 12/21 (57%) Query: 70 LFLASDDAKHITGLNLRLHAG 90 LFL S A HIT NL + G Sbjct: 236 LFLVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 29.2 bits (65), Expect = 0.002 Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 4 LDGRVSLITGTAGGQGLSHAVRLTIAGADVIAVD 37 ++G+++ ITG A G G + A L GA + AVD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD 39
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.5 bits (74), Expect = 0.003 Identities = 15/91 (16%), Positives = 27/91 (29%), Gaps = 11/91 (12%) Query: 62 LAEQLLNSYNHSTTQIDGLDIAFLHIRSPHADATPLLMTHGWPGSVLEFRHVIAPLTHPQ 121 L + + D +A L+ H WPG+V E +++ LT Sbjct: 320 LVRHFVQQAEKEGLDVKRFD----------QEALELMKAHPWPGNVRELENLVRRLTALY 369 Query: 122 DHGGAVSDAFHLVIPS-LPGFGFSQPPTEPG 151 + + S +P + G Sbjct: 370 PQDVITREIIENELRSEIPDSPIEKAAARSG 400
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.9 bits (64), Expect = 0.001 Identities = 23/74 (31%), Positives = 31/74 (41%), Gaps = 15/74 (20%) Query: 1 MVQPGSTDT------------EANPADGPMAAIFRDATPLGRYADPSDIAAADPSDLSDI 48 +V PGST+T G F+ PL + A PSDIA A +S Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKG-SLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 49 AA--TVAHLAGEGG 60 A T+ +L +GG Sbjct: 243 AGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.2 bits (104), Expect = 1e-08 Identities = 11/71 (15%), Positives = 28/71 (39%) Query: 19 RHGNRVQAEIIEAARALFGARGYHGVTVEAFGEASGRTGTSVYRCFANRTAIFRVLMADL 78 + + I++ A LF +G ++ +A+G T ++Y F +++ +F + Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 79 WPTGSDALAGR 89 + Sbjct: 67 ESNIGELELEY 77
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.2 bits (81), Expect = 0.001 Identities = 43/205 (20%), Positives = 69/205 (33%), Gaps = 35/205 (17%) Query: 610 LGPTGVGKTELARTLSEALFDAEEAMIRIDMSEYQERHTVSRLIGSPPGYVGYEEGGQLT 669 G +G GK +AR L + + I+M+ S L G E G T Sbjct: 166 TGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFT 217 Query: 670 EAVRRKPYSV-------VLFDEIEKAHPDVFNTLLQVLDDGRLTDARGRTVNFTNTVIIM 722 A R + DEI D LL+VL G T GRT ++ I+ Sbjct: 218 GAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVA 277 Query: 723 TSNIGSQWLMDAVTPDGKIEPEARARVMAELRERFRPEFLNRLDEIVLFKPLTLAEIEQV 782 +N + L ++ + FR + RL+ + L P E + Sbjct: 278 ATN---KDLKQSIN-----------------QGLFREDLYYRLNVVPLRLPPLRDRAEDI 317 Query: 783 VDLLVEDLRRRLADRRITLEITEPA 807 DL+ +++ + + A Sbjct: 318 PDLVRHFVQQAEKEGLDVKRFDQEA 342
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 117 bits (296), Expect = 4e-31 Identities = 57/296 (19%), Positives = 119/296 (40%), Gaps = 46/296 (15%) Query: 43 TAGKEDAVRIV---VRGREYAPEEISAMVLRKLADDAAKFLGEKVTEAVITVPAYFNDAQ 99 T G A+R + V + E++ ++++ ++ ++ VP + Sbjct: 66 TPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS---FMRPSPRVLVCVPVGATQVE 122 Query: 100 RQSTKDAGRIAGLDVLRIINEPTAAALAYGMDKRSHETVLVFDLGGGTFDVSVLDVGDGI 159 R++ +++ + AG + +I EP AAA+ G+ +V D+GGGT +V+V+ + G+ Sbjct: 123 RRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-GV 181 Query: 160 VEVRATAGDTHLGGNDWDRRLVDFLADEFRNQTGIDLRNDPQALQRLFEAAEKAKVELST 219 V + +GG+ +D +++++ + + G AE+ K E+ + Sbjct: 182 V----YSSSVRIGGDRFDEAIINYVRRNYGSLIGE-------------ATAERIKHEIGS 224 Query: 220 VSQ----TQINLPFITADANGPRHL---NTTITRSQFEKITADL------LERCLPPLRQ 266 +I + PR + I + E +T + LE+C P L Sbjct: 225 AYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELAS 284 Query: 267 AMADAKVSEQDLDEVILVGGATRMPAVQALVRRLTAGKEPNMTVNPDEVVAVGAAI 322 +++ ++L GG + + L+ T G + +P VA G Sbjct: 285 DISERG--------MVLTGGGALLRNLDRLLMEET-GIPVVVAEDPLTCVARGGGK 331
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 2e-28 Identities = 75/259 (28%), Positives = 125/259 (48%), Gaps = 20/259 (7%) Query: 9 LDGRVAVVTGASSGLGVDFARGLAQAGADVVLGARRVDRLATTAETVEKEGRRALAVATD 68 ++G++A +TGA+ G+G AR LA GA + ++L +++ E R A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 VADPASCDALVVAAVEAFGRVDILVNNAGIGTAVPALRETPQQFRSVIDVNLNGCYWMAQ 128 V D A+ D + G +DILVN AG+ + +++ + VN G + ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 129 AAARVM--RPGSSIVNISSILGLTTAGLPQ---AAYAASKAGLIGMTRDLAQQWTGRRGI 183 + ++ M R SIV + S AG+P+ AAYA+SKA + T+ L + I Sbjct: 126 SVSKYMMDRRSGSIVTVGS----NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE-YNI 180 Query: 184 RVNALAPGFFRSEM-----TDEYQP-----GYLDAQMSRVLGGRLGEPEELTAALVFLTS 233 R N ++PG ++M DE G L+ + + +L +P ++ A++FL S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 234 DAGSFVTGQTLAVDGGFTV 252 +T L VDGG T+ Sbjct: 241 GQAGHITMHNLCVDGGATL 259
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 39.7 bits (92), Expect = 8e-05 Identities = 23/89 (25%), Positives = 42/89 (47%), Gaps = 2/89 (2%) Query: 572 ILHDMLDALEYAHQRKVLHRDVSPNNIIVD-ADDRATLIDFGVASDGADHSIVGTLPYQA 630 I H +LD + + V+H D+ P N++ D A +ID G+ S + T ++A Sbjct: 250 IAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKA 309 Query: 631 PEIAAGR-SWSDAADLYSLAVVCFEALTG 658 PE+ G S+ +D++ + + G Sbjct: 310 PELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>PF07675#Cleaved Adhesin Length = 1358 Score = 28.5 bits (63), Expect = 0.039 Identities = 20/72 (27%), Positives = 30/72 (41%), Gaps = 3/72 (4%) Query: 9 KWE---ERQAPGSRRSIAQGLGIVTDALFDAPVPAEFAELVREALAGWSFNTGARTVTGR 65 KW+ ++A GSR G G+ V A A++V A W NTG + + Sbjct: 351 KWDAPSAKKAEGSREVKRIGDGLFVTIEPANDVRANEAKVVLAADNVWGDNTGYQFLLDA 410 Query: 66 DGRSREATPPAG 77 D + + PA Sbjct: 411 DHNTFGSVIPAT 422
>INTIMIN#Intimin signature. Length = 939 Score = 32.7 bits (74), Expect = 0.005 Identities = 49/242 (20%), Positives = 77/242 (31%), Gaps = 22/242 (9%) Query: 61 VTCTTDPSGYCTVGLQMLPVPAAVVVEPT--------APLIHAVDQVTASAFRVQFLTST 112 + T+ SG TV L+ VV T A + VDQ AS ++ +T Sbjct: 610 NSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTT 669 Query: 113 GAPAASRQITFGYTAYAGGNPGPGPAPTSTAPTVTPTGAPVLSTTIEDTAIGTTTNTV-S 171 IT+ G P T T T + ++T + G T+ S Sbjct: 670 AVANGQDAITYTVKVMKGDKPVSN-----QEVTFTTTLGKLSNSTEKTDTNGYAKVTLTS 724 Query: 172 YTPA-ANWHQCAAGCNTAVASTANSSYRWASATGDKVTITWAGVQLKVYGVKEPQGGIDS 230 TP + + V + + + + I GV+ K+ V G ++ Sbjct: 725 TTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNL 784 Query: 231 IATDGAGQGTADWYRA-AGQAPDLVWTSPVLASGNHTTIITLTGQHNPQATGGPTLTFDK 289 A+ G G W A A + V TT I++ N T T Sbjct: 785 KAS--GGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQT----ATYTIAT 838 Query: 290 AD 291 + Sbjct: 839 PN 840
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 44.5 bits (105), Expect = 1e-06 Identities = 53/284 (18%), Positives = 85/284 (29%), Gaps = 86/284 (30%) Query: 200 TGGGQTVAILEFGGGYSLPDLA------TYWSAIGHTPPQ-----------VSSISVDGA 242 G G VA+L+ G PDL ++ P+ V+ + Sbjct: 39 RGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGT-IAAT 97 Query: 243 ANSPGSDGGSVETMLDIAILSAVAPQARQAVY-VAPNTSAGFVDAYLAAIHDTVTSPC-A 300 N G G VAP+A + V +G D + I+ + Sbjct: 98 ENENGVVG--------------VAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDI 143 Query: 301 ISLSWGSAEQNWTPAAISALEDVLHTAALFGITCTCSSGDDGSSDGVHDGLAHADYPASS 360 IS+S G P + L + + A I C++G++G D D L YP Sbjct: 144 ISMSLGG------PEDVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELG---YPGCY 194 Query: 361 PWMLACGGTTLVRTGQTITDEVVWDWGGADGNSGGGISDLFDLPDYQASTNIPPSINPGS 420 +++ G + N + Sbjct: 195 NEVISVGAIN-------------------------------------FDRHASEFSNSNN 217 Query: 421 RIGRGGPDVATAAADGTSIVLVGGQWAVIGGTSAVSPMLAGLAA 464 D+ D S + GG++A GTS +P +AG A Sbjct: 218 -----EVDLVAPGEDILS-TVPGGKYATFSGTSMATPHVAGALA 255
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 32.9 bits (74), Expect = 0.009 Identities = 41/139 (29%), Positives = 58/139 (41%), Gaps = 10/139 (7%) Query: 612 GLRGQFQPPTRDPAGTLTLRPGRPAPQGAAGAAAAAGSAVRAVGRQVTPALTLARGGFEG 671 GL +PP G G + A A AA G+AV AVG A ++A G Sbjct: 48 GLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAV-AVG-----AGSIATGVNSV 101 Query: 672 QLNP-GEILGWQSVAVRAGRLAREAFDGAGEAIRGMTSAVRLAVGWGERHQALVRSWAVG 730 + P + LG +V A A++ DG R TS +AVG+ + A S A+G Sbjct: 102 AIGPLSKALGDSAVTYGAASTAQK--DGVAIGARASTSDTGVAVGFNSKADA-KNSVAIG 158 Query: 731 IGLVVGAIGAWRLATGALA 749 V A + +A G + Sbjct: 159 HSSHVAANHGYSIAIGDRS 177
>INTIMIN#Intimin signature. Length = 939 Score = 28.9 bits (64), Expect = 0.043 Identities = 11/36 (30%), Positives = 15/36 (41%) Query: 61 AAGGLVQYPWTLEDTAAPGNLAGEWHVTLPGGASET 96 A+GG +Y W + A A VTL + T Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTT 821
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 35.7 bits (82), Expect = 4e-04 Identities = 23/110 (20%), Positives = 39/110 (35%), Gaps = 5/110 (4%) Query: 117 VHPTPPPPQPVPPPPAGAATGVEDTGPDAGGDAGLPEPADPAT----TSGAGSTSPAVRA 172 + P P+P P P D P A E PA T+ A ++ P Sbjct: 94 IEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSV 153 Query: 173 PVGAMSAHRPPAADPARRPQTAVAGRARMGAYMSATGSP-HVRVGDAIDS 221 G + R PAR + G+ ++ ++ G +V++ A + Sbjct: 154 ASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPA 203
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 26.1 bits (57), Expect = 0.010 Identities = 10/58 (17%), Positives = 20/58 (34%) Query: 1 MREYRIILVAAAVLIVITLVAVWGYRHLPPPPSHRPLVVPRSTDRPPSTPSRPAATRA 58 M R +LV A + + + W P P + + + + PA+ + Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQG 58
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 33.0 bits (75), Expect = 0.004 Identities = 19/103 (18%), Positives = 32/103 (31%), Gaps = 8/103 (7%) Query: 446 PTPEQLLMQLIARLKALPPPVVQAVVQR--MDPTLKIKEVVPPPIQEPDGNGNEPSEQDP 503 P P Q + + L PP ++P + + + PP + P + P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98 Query: 504 P------AEQGPPEDDEPPTGPPANPSHAVQPITAAGGRGTDP 540 ++ P D +P PA+P P T Sbjct: 99 KPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAA 141
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.5 bits (63), Expect = 0.040 Identities = 23/98 (23%), Positives = 35/98 (35%), Gaps = 16/98 (16%) Query: 94 GHRVLEVGAGTGYNAALMAAIVGTSGHITAVDIDEDLVESARTHLAAAGVTNVDVVLGDG 153 G GA G A+ + HI AVD + + +E + L A Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEAR---------- 57 Query: 154 AFGHPDAAPYDRVIATVGAVETPTA-WLDQLAPAGRLV 190 H +A P D + A++ TA ++ P LV Sbjct: 58 ---HAEAFPAD--VRDSAAIDEITARIEREMGPIDILV 90
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.9 bits (72), Expect = 0.004 Identities = 23/56 (41%), Positives = 31/56 (55%), Gaps = 4/56 (7%) Query: 9 DGAAGIALLHQETGARAAMYTALE---QAVADGVSIADSASLYYGAPALAFVLAGT 61 DG + +A H+ETGA A T + +V+ G+S A + SL GAP A V A T Sbjct: 349 DGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSL-VGAPVSALVGAVT 403
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 29.4 bits (66), Expect = 0.029 Identities = 11/51 (21%), Positives = 22/51 (43%), Gaps = 2/51 (3%) Query: 81 IARMLGQAADALNGLDGRHVLEIGSGGYNASLLRELVGASGSVTTVDIDRE 131 + + +G A A+ G+D ++ G N +RE + +D+E Sbjct: 309 VKKTIGSYAAAMGGVDV--IVFTAGIGENGPEIREFILDGLEFLGFKLDKE 357
>SECA#SecA protein signature. Length = 901 Score = 29.1 bits (65), Expect = 0.023 Identities = 25/92 (27%), Positives = 35/92 (38%), Gaps = 15/92 (16%) Query: 201 DRYAEVWQDATATGPVTMSTPMVVLAAR----RVAGDPLAPVAGPARRLPLLAEPIRSPR 256 A + A VT++T M A R + G A VA E I++ Sbjct: 485 ANEAAIVAQAGYPAAVTIATNM---AGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADW 541 Query: 257 PEAERAIMDALGRHRRRWDDLVAGT-RRESRR 287 A+++A G H + GT R ESRR Sbjct: 542 QVRHDAVLEAGGLH-------IIGTERHESRR 566
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 28.5 bits (63), Expect = 0.010 Identities = 25/85 (29%), Positives = 33/85 (38%), Gaps = 2/85 (2%) Query: 47 KDSRGTFPFWGYLLDAEGFD-MHFIVHPRGWTPNDVRHLNEGVEALRCRDLSISVLDAHT 105 S PF G+ L FD F H W P+ R L + L+ + H Sbjct: 2 LTSHFPLPFAGHRLHIVDFDASSFREHDLLWLPHHDR-LRSAGRKRKAEHLAGRIAAVHA 60 Query: 106 LRVQEIPAGYGVGDIQAALWPHGLV 130 LR + G+GD + LWP GL Sbjct: 61 LREVGVRTVPGMGDKRQPLWPDGLF 85
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 3e-08 Identities = 22/200 (11%), Positives = 54/200 (27%), Gaps = 11/200 (5%) Query: 19 RTSRQSDLFDALVEIFLAEGFARFTLADLAGRLRCSKSTLYTLAHSKEQLAVAVVVHFFR 78 + + D + +F +G + +L ++A ++ +Y K L + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 79 SAAERIDDSLRSAP-DPADRLRRYLDGV--AAELRPASAAFRADL---AAFPPARAIYER 132 + E + P DP LR L V + + F A+ ++ Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 133 NTSIAA----AKLRTLVAEGVAVGVFRE-VDARFVGQVATLAMVGIQQGTIERQTGLADA 187 ++ + + + + R + + G+ + + Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 188 DAYAQLAGLLLHGLARRDGD 207 +LL Sbjct: 189 KEARDYVAILLEMYLLCPTL 208
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 28.5 bits (63), Expect = 0.006 Identities = 12/26 (46%), Positives = 15/26 (57%) Query: 55 SGSRGQAVHAVQDASHTLDPHYQPKL 80 + S Q A+QDA + DPHY KL Sbjct: 262 AASAEQGAQALQDAGYATDPHYARKL 287
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 27.8 bits (61), Expect = 0.033 Identities = 18/52 (34%), Positives = 26/52 (50%), Gaps = 3/52 (5%) Query: 33 SLRLGVVTNDIY-TTEDADFLRRAGVLDPQRIRAVETGCCPHTAIRDDITAN 83 S RL + N + T D +L+ G R R ++ CC TA+R D+ AN Sbjct: 198 SSRLTTLRNTLAPATNDPRYLQACGGEKLNRFRDIQ--CCRQTAVRADLNAN 247
>PF06704#DspF/AvrF protein Length = 129 Score = 27.5 bits (61), Expect = 0.017 Identities = 13/40 (32%), Positives = 18/40 (45%), Gaps = 5/40 (12%) Query: 130 EGLLARCFQHEVDHLDGTLYLDRLTG-----EERRAAVQA 164 +G + C Q E+ LD + D G E RA +QA Sbjct: 90 QGDVRLCAQRELAVLDEAQFCDTARGFIVQAREARALLQA 129
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.2 bits (68), Expect = 0.017 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 8/69 (11%) Query: 119 DIRAIREAVLAGAPERA-LAFWAGEYRLNARIRRFPKPYIAIM---DGIVMGGGIGVSAH 174 D R + +A +RA LA YR +++ Y A M D IV GIG + Sbjct: 282 DFRDLEDAAFKNGDKRAQLALNVFAYR----VKKTIGSYAAAMGGVDVIVFTAGIGENGP 337 Query: 175 GGVRIVTER 183 + + Sbjct: 338 EIREFILDG 346
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.8 bits (69), Expect = 0.008 Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 8/54 (14%) Query: 72 AIDGQILLDGEDLVTAPAERVRGLRGRRMAMIFQDPLSSMHPQFTVGEQIVEAY 125 +I+ +G+D ER R A+ DPL + P T+ E + A+ Sbjct: 515 ETTARIIFNGKD--LNLVER------RIAAVNPSDPLETTKPDMTLKEALKIAF 560
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.0 bits (80), Expect = 0.003 Identities = 20/59 (33%), Positives = 25/59 (42%), Gaps = 3/59 (5%) Query: 489 EAPPPTAPRAGAGAPGSPAGADSPGARRDPASAGQSAAP---AAAATVMATATATASAT 544 +A P AG + A +R S G++A P AAA TVMATA A Sbjct: 476 KAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVK 534
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.9 bits (77), Expect = 0.007 Identities = 22/119 (18%), Positives = 46/119 (38%), Gaps = 5/119 (4%) Query: 2578 VEARGGQARYRQ---LDVLDADAVQQAVKQVFARHGRLDGVVYSAGVIEDALVADKDPQS 2634 V + +AR+ + DV D+ A+ + ++ G +D +V AGV+ L+ + Sbjct: 49 VSSLKAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEE 108 Query: 2635 FRRVFDTKVAGARTLLAALAELPVAPR--FLAFFGSIAGVLGNRGQGDYAAANDALETL 2691 + F G ++++ + R + GS + YA++ A Sbjct: 109 WEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMF 167
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.9 bits (186), Expect = 2e-18 Identities = 50/187 (26%), Positives = 82/187 (43%), Gaps = 2/187 (1%) Query: 6 KVVVVTGGGRGIGAALADQAAGAGARAVVVADIDLTVARATAQRVGLNGTAVEAVRADVG 65 K+ +TG +GIG A+A A GA + D + + EA ADV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 66 SPADLDELARRTREMFGSVDVFFSNAGIAAGAGVDATAR-QWARAWSINVMSHVHAARIV 124 A +DE+ R G +D+ + AG+ + + + +W +S+N +A+R V Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 125 LPSMLERDSGAFVITASAAGLLNIPGDAPYAVTKGAAVALAEWLALTHGGRGVQISVLCP 184 M++R SG+ V S + A YA +K AAV + L L ++ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 185 LGVRTDM 191 TDM Sbjct: 188 GSTETDM 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.6 bits (157), Expect = 3e-15 Identities = 35/203 (17%), Positives = 72/203 (35%), Gaps = 20/203 (9%) Query: 5 QRMRVDARLNRERILAAAEEVFGELGAQA-STEEVARRAGVGVATVFRHFPTKTDLVEAT 63 ++ + +A+ R+ IL A +F + G + S E+A+ AGV ++ HF K+DL Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 64 LVRHFDDLVAHARTLAAAPAPGPA------LGDLVTAMVERGATKVTL------ANLLGA 111 ++ A P L ++ + V ++ + +G Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 112 TDQVPSGAADAARRLRDAVDAVLRRAQDAGVARLDVSVDELYFLVRG-----LTQAAAAM 166 V + D ++ L+ +A + D+ ++RG + A Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 167 PVPTA--VSRGAVAVVLDGLAAR 187 +R VA++L+ Sbjct: 183 QSFDLKKEARDYVAILLEMYLLC 205
>PF05860#haemagglutination activity domain. Length = 117 Score = 26.7 bits (59), Expect = 0.005 Identities = 12/35 (34%), Positives = 15/35 (42%), Gaps = 4/35 (11%) Query: 10 VTSGHASLSSGLLEESGRALV----PTGDPFGGWA 40 VT G S GL+ + A + P G FG A Sbjct: 64 VTGGSVSNIDGLIRANATANLFLINPNGIIFGQNA 98
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 39.6 bits (92), Expect = 5e-06 Identities = 43/186 (23%), Positives = 61/186 (32%), Gaps = 39/186 (20%) Query: 20 VDPNRWALLTIDVQNDFVRADGPGTIAGTEALLPAMARAAAGFRTAGLPVFHLVRLYLPD 79 DPNR LL D+QN FV A F PV L Sbjct: 26 PDPNRAVLLIHDMQNYFVDA----------------------FTAGASPVTELS------ 57 Query: 80 GSNAERCRRASIAAGLRLVCPGSDGSQLHPT-------LAPPGGGVRLDERALLAGATQR 132 +N + + + G+ +V GSQ +P PG E ++ Sbjct: 58 -ANIRKLKNQCVQLGIPVVYTAQPGSQ-NPDDRALLTDFWGPGLNSGPYEEKIITELAP- 114 Query: 133 VGPREWVLFKPRWGGFYATRLADELRALGVGTVAVVGANFPNCPRTTVYEASERDFDVVV 192 + VL K R+ F T L + +R G + + G T EA D Sbjct: 115 -EDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFF 173 Query: 193 VADAIS 198 V DA++ Sbjct: 174 VGDAVA 179
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.9 bits (85), Expect = 1e-04 Identities = 16/61 (26%), Positives = 20/61 (32%) Query: 442 AMATQQRQPATPPPPPPPPPPPPSRPGPPPAPRAPGWTPDLPCAAGPTTPPVRPPASRPR 501 + Q PPP P P P P P P AP P PV+ +P+ Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPK 111 Query: 502 P 502 Sbjct: 112 R 112 Score = 33.0 bits (75), Expect = 0.002 Identities = 19/98 (19%), Positives = 22/98 (22%) Query: 446 QQRQPATPPPPPPPPPPPPSRPGPPPAPRAPGWTPDLPCAAGPTTPPVRPPASRPRPAAT 505 + P P P P PP P P+ P P RPA+ Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASP 124 Query: 506 EGYGDGDGPTIPLRGWVLPPPPAPRLIPPPALDDGSPA 543 T P P AL P Sbjct: 125 FENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQ 162
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.5 bits (76), Expect = 3e-04 Identities = 19/88 (21%), Positives = 28/88 (31%), Gaps = 1/88 (1%) Query: 58 TARKEAAAQQHGISADWFTRSELEPMSLALAMELDQQLRRREGRTATDPYRYRDPAVLPP 117 T KE A + A T E + + +Q + + +P R DP V Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVT-SQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 118 PPPATSYRPRPATTPAAPTPPRREPPAE 145 P + + PA T E P Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVT 1184
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.013 Identities = 15/40 (37%), Positives = 21/40 (52%), Gaps = 5/40 (12%) Query: 12 MKIGIIG-AGQIGGTLTRRLSELGHQVR----VANSRDPQ 46 MK + G AG IG +++RL E GHQV + + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVS 40
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (304), Expect = 5e-32 Identities = 84/392 (21%), Positives = 168/392 (42%), Gaps = 19/392 (4%) Query: 8 VLDITIVNVALPRIRESLGFSATDLAWVINAYTLAYGGLLLLGGRAGDLMGRRATLLGGI 67 VL+ ++NV+LP I WV A+ L + + G+ D +G + LL GI Sbjct: 27 VLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGI 86 Query: 68 ALFTIASLLG--GLSTAPWMLVAARVGQGVGAACASPNALALIAANFPPGPARTRAMGAW 125 + S++G G S L+ AR QG GAA A P + ++ A + P R +A G Sbjct: 87 IINCFGSVIGFVGHSFFSL-LIMARFIQGAGAA-AFPALVMVVVARYIPKENRGKAFGLI 144 Query: 126 AAVAGVGGSIGLIAGGMLTTWLSWRWVMFINVPFGLVI-LLLAPRYLRTPPRREGRFDAA 184 ++ +G +G GGM+ ++ W ++ + +P +I + + L+ R +G FD Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSYL--LLIPMITIITVPFLMKLLKKEVRIKGHFDIK 202 Query: 185 GALSSVVGLASGVYGFLRASSDGWADGRTLGAFLLAVVALAAFLVVESRAAQPVVPLRLV 244 G + VG+ + +S +++V++ F+ + P V L Sbjct: 203 GIILMSVGIVFFMLF---TTSYSI------SFLIVSVLSFLIFVKHIRKVTDPFVDPGLG 253 Query: 245 AEAARARTYLLMLLLTGSMLSMFFFGTQVLQEVLGLSALRAGLAFL-PLSLGILVSASRA 303 L ++ G++ ++++V LS G + P ++ +++ Sbjct: 254 KNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIG 313 Query: 304 SRLLPRTGPKPLMLVGAALSTGGMLWLAQVSVTSSYISVVLGPLLLFGAGLGLLFVPLSV 363 L+ R GP ++ +G + L + + T+S+ + + + + G GL +S Sbjct: 314 GILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWF-MTIIIVFVLG-GLSFTKTVIST 371 Query: 364 SLVAGVPAEHSGAAASMMVTTQQVGGSLGLAV 395 + + + + +GA S++ T + G+A+ Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 0.003 Identities = 15/69 (21%), Positives = 22/69 (31%) Query: 413 QQVRSGPSTTAPANAGSPAGEPAAEAPPPAESLAEAPPPAESTAEESPERAPAAAPQGAP 472 Q+V S +P S +P AE + P T + PA Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 473 ERPIPVPAT 481 E+P+ T Sbjct: 1180 EQPVTESTT 1188
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.3 bits (128), Expect = 2e-10 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 2 RVALADDAALFREGLLLLLTTAGYEVVGCVADGDALLDLLAVEPVDVAIVDIRMPPGAEG 61 + +ADD A R L L+ AGY+V ++ L +A D+ + D+ MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDEN-- 61 Query: 62 GLTTAARVRARHPDTGLLLLSHYAE 86 R++ PD +L++S Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNT 86
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 62.5 bits (152), Expect = 9e-13 Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 27/225 (12%) Query: 140 EVARLAGVGDVRMVTEPVAAATHYTAVRPLPPGAIIAVYDLGGGTFDTAVLRFRAGGTEI 199 E A+ AG +V ++ EP+AAA A P+ V D+GGGT + AV+ G Sbjct: 128 ESAQGAGAREVFLIEEPMAAAI--GAGLPVSEATGSMVVDIGGGTTEVAVISL-NGVVYS 184 Query: 200 LGLPEGVEWLGGLDFDEAVVHHVDRELGGAVSDIDPQDHAGAVALARLRQECVLAKEALS 259 + +GG FDEA++++V R G + G R++ E A Sbjct: 185 SSVR-----IGGDRFDEAIINYVRRNYGSLI---------GEATAERIKHEIGSAYPGDE 230 Query: 260 FDEETVIPVFLPTARA-EVRLTRARFEDMVRPAIHSTVDALHRTLSSAGVEPADLSA--- 315 E V L L + ++ + V A+ L P +L++ Sbjct: 231 VREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQC---PPELASDIS 287 Query: 316 ---VLLAGGSSRIPAVARTVESALGRPTVVNAHPKHLVALGAARI 357 ++L GG + + + R + G P VV P VA G + Sbjct: 288 ERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKA 332
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 118 bits (297), Expect = 5e-31 Identities = 88/415 (21%), Positives = 164/415 (39%), Gaps = 22/415 (5%) Query: 33 SGRRPGLILAFLSIAGFMTFLDVSIVNVALPTIEDKLDISATRLPYVVTTYGMVLGGFLL 92 S R IL +L I F + L+ ++NV+LP I + + +V T + + Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67 Query: 93 LCGRLADTYGRRLMLQTGLTLFALSSLLGGFAQEAVQ-LIVARGLQGLG-AAFLATSALS 150 + G+L+D G + +L G+ + S++G LI+AR +QG G AAF A + Sbjct: 68 VYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 151 LLTSSFPEGPARTRALGVWGSLSGVASVAGVTLGGLLTDGPGWRWIFFINVPIGLLGALL 210 + E R +A G+ GS+ + G +GG++ W ++ I + I ++ Sbjct: 128 VARYIPKE--NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPF 184 Query: 211 APGVVNESRADRRSSSFDLAGAVTLTAGLVLLIFSLGQTVDDSDPPVGLIAAGFTV-SAL 269 ++ + R FD+ G + ++ G+V + + F + S L Sbjct: 185 LMKLLKK--EVRIKGHFDIKGIILMSVGIVFFMLF-----------TTSYSISFLIVSVL 231 Query: 270 LLGAFLLIERRARDPLITLGILRRPSLRAANLAAVLLFGNVVTLFFFASLFMQQVLDYSP 329 F+ R+ DP + G+ + L ++FG V M+ V S Sbjct: 232 SFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLST 291 Query: 330 LRTGLAYV-PLAVIVAVGAGIAAQLVTRVPVGLVLMIGLLLTVGGMLLLFRAPVDASYPV 388 G + P + V + I LV R VL IG+ L + + + Sbjct: 292 AEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTA--SFLLETTSW 349 Query: 389 DLLPAFLGTGLGLGLSFVPIQVVAFTGVREHESGLAAGLINTSQEVGGAIGLAVA 443 + + GL + I + + +++ E+G L+N + + G+A+ Sbjct: 350 FMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>cloacin#Cloacin signature. Length = 551 Score = 48.6 bits (115), Expect = 4e-08 Identities = 37/110 (33%), Positives = 39/110 (35%), Gaps = 2/110 (1%) Query: 294 GVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGTPGGGVPGGGTPGGGVPGGGVPGGGTPGG 353 G G G G G GG G GV GG + G G P GG G G+ GG G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 354 GVPGGGVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGTPGGGVPGGGTPGG 403 G GG GG G G G G P TPG G G Sbjct: 63 GNGGGNGNSGGGSGTG--GNLSAVAAPVAFGFPALSTPGAGGLAVSISAG 110 Score = 46.6 bits (110), Expect = 2e-07 Identities = 40/119 (33%), Positives = 46/119 (38%), Gaps = 7/119 (5%) Query: 319 GVPGGGTPGGGVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGVPGG 378 G G G G G GG G GV GG + G G P GG G G+ GG G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 379 GTPGGGVPGGGTPGGGVPGGGTPGGGTPGG-GTPGGGTPGGGTPG---SGGSHTVTVTD 433 G GG G + GG GG P G P TPG G S G+ + + D Sbjct: 63 GNGGGN---GNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIAD 118 Score = 46.6 bits (110), Expect = 2e-07 Identities = 34/103 (33%), Positives = 37/103 (35%), Gaps = 2/103 (1%) Query: 293 GGVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGTPGGGVPGGGTPGGGVPGGGVPGGGTPG 352 G G GG G GV GG + G G P GG G G GG G G GG Sbjct: 12 GAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS 71 Query: 353 GGVPGGGVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGTPGGGV 395 GG G G G + G P TPG G G + Sbjct: 72 GGGSGTG--GNLSAVAAPVAFGFPALSTPGAGGLAVSISAGAL 112 Score = 42.4 bits (99), Expect = 4e-06 Identities = 30/89 (33%), Positives = 34/89 (38%), Gaps = 2/89 (2%) Query: 290 PGVGGVPGGGTPGGGVPGGGVPGGGTPGGGVPGGGTPGGGVPGGGTPGGGVPGGGVPGGG 349 P GV GG + G G P GG G G+ GG G G GG GG G G G Sbjct: 24 PTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG--GNL 81 Query: 350 TPGGGVPGGGVPGGGTPGGGVPGGGVPGG 378 + G P TPG G + G Sbjct: 82 SAVAAPVAFGFPALSTPGAGGLAVSISAG 110 Score = 30.8 bits (69), Expect = 0.014 Identities = 23/88 (26%), Positives = 28/88 (31%) Query: 261 GVGGVPGVGGVPCVTDKPVTDKPNGIPCVPGVGGVPGGGTPGGGVPGGGVPGGGTPGGGV 320 G G+ GG + + P G G+ G G GG G G GT G Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLS 82 Query: 321 PGGGTPGGGVPGGGTPGGGVPGGGVPGG 348 G P TPG G + G Sbjct: 83 AVAAPVAFGFPALSTPGAGGLAVSISAG 110
>cloacin#Cloacin signature. Length = 551 Score = 27.4 bits (60), Expect = 0.043 Identities = 15/46 (32%), Positives = 17/46 (36%) Query: 132 HDGGYGTFVGAAAGGRGDGGGGSGGGSGSGRSVGGPPATDDGDLGI 177 H+ G + G GG G G G GSG S P GI Sbjct: 9 HNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGI 54 Score = 27.4 bits (60), Expect = 0.048 Identities = 15/33 (45%), Positives = 17/33 (51%), Gaps = 1/33 (3%) Query: 134 GGYGTFVGAAAGGRGDGGGGSGGGSGSGRSVGG 166 GG G+ + GG G G GG G SG G GG Sbjct: 48 GGSGSGIHWG-GGSGHGNGGGNGNSGGGSGTGG 79
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 36.3 bits (83), Expect = 4e-04 Identities = 43/150 (28%), Positives = 65/150 (43%), Gaps = 27/150 (18%) Query: 137 RGGVVHRDVKPGNVLVTN-DGQARLTDFGIAVTEGDAT--LTEAGTLVGSPAYIAPERAR 193 + GVVH D+KPGNV+ G+ + D G+ G+ TE ++ APE Sbjct: 263 KAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTE--------SFKAPELGV 314 Query: 194 GARVGAA--GDVWGLGATLFTAVEG------VPPFQGEGPLAILAAVVEDRRRPFQHSGP 245 G +GA+ DV+ + +TL +EG + P QG + A V D H Sbjct: 315 G-NLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMDENGYPIHRPG 373 Query: 246 LRGI-------LTELLDSDPARRPSLAEAR 268 + G+ +T++L RP EAR Sbjct: 374 IAGVETAYTRFITDILGVSADSRPDSNEAR 403
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (288), Expect = 7e-33 Identities = 84/274 (30%), Positives = 136/274 (49%), Gaps = 24/274 (8%) Query: 4 VEGKVALVTGAARGQGRSHAVRLAQEGADLILLDVLEDLPTLDYPLGTGDDLAETVAAVE 63 +EGK+A +TGAA+G G + A LA +GA + +D + L + V++++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDY------------NPEKLEKVVSSLK 53 Query: 64 AAGRRVVWDKADVRDFDAVADLVARGVAELGGLDVVSANAGISPRLAKLWEITAQEWDDQ 123 A R ADVRD A+ ++ AR E+G +D++ AG+ R + ++ +EW+ Sbjct: 54 AEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEAT 112 Query: 124 IAVNLTGVFNTIRAVVPPMIAAGRGGAIVLTSSGAGLAGIPH--LGAYNASKHGVVGLAL 181 +VN TGVFN R+V M+ R G+IV S AG+P + AY +SK V Sbjct: 113 FSVNSTGVFNASRSVSKYMMDR-RSGSIVTVGSNP--AGVPRTSMAAYASSKAAAVMFTK 169 Query: 182 TLANELARHDIRVNALCPGTVGTPMVTENRSQHRFFRPDLEAPGLAETKATLAKVSPLGR 241 L ELA ++IR N + PG+ T M + + + + T PL + Sbjct: 170 CLGLELAEYNIRCNIVSPGSTETDM-----QWSLWADENGAEQVIKGSLETFKTGIPLKK 224 Query: 242 PWIEPIDVTNALLWLVSDEGRYVTGVALPIDQGT 275 +P D+ +A+L+LVS + ++T L +D G Sbjct: 225 -LAKPSDIADAVLFLVSGQAGHITMHNLCVDGGA 257
>cloacin#Cloacin signature. Length = 551 Score = 35.1 bits (80), Expect = 0.001 Identities = 21/55 (38%), Positives = 25/55 (45%) Query: 692 GAGQTGGAGGFGGFGRRSGGFGGRSGGFGGRSGGFGGRSGGFGGRSGGFGGRSGG 746 G G GGA G+ + +GG SG GG G +GG G SGG G G Sbjct: 26 GLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 35.1 bits (80), Expect = 0.001 Identities = 27/78 (34%), Positives = 32/78 (41%), Gaps = 10/78 (12%) Query: 319 GYNGLGRIFGGDGNRG-GGGGGFGGGRANLGELARRDPQLAERVQAALGGRGGGGRGGGG 377 G+N G+ N G G G GG G + +P GG G G GG Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPW---------GGGSGSGIHWGG 58 Query: 378 GFGGGRGFGGGGFGGGAG 395 G G G G G G GGG+G Sbjct: 59 GSGHGNGGGNGNSGGGSG 76 Score = 32.8 bits (74), Expect = 0.006 Identities = 25/66 (37%), Positives = 29/66 (43%), Gaps = 7/66 (10%) Query: 692 GAGQTGGA--GGFGGFGRRSG-----GFGGRSGGFGGRSGGFGGRSGGFGGRSGGFGGRS 744 GA T G GG G G G G+ + +GG SG GG G +GG G S Sbjct: 12 GAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS 71 Query: 745 GGPGGT 750 GG GT Sbjct: 72 GGGSGT 77
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 77.7 bits (191), Expect = 5e-20 Identities = 34/170 (20%), Positives = 63/170 (37%), Gaps = 9/170 (5%) Query: 14 PRRGRRRSEGSRDAILQAAAELVIEHGYAAVSIEKIAQRAGVGKQTIYRWWPSKGDVLME 73 R+ ++ ++ +R IL A L + G ++ S+ +IA+ AGV + IY + K D+ E Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 74 ALARKADVHITLPDE------GSWAADLRHLLDDSFALAREPQLGELLRALMVEAQLDP- 126 L E G + LR +L + LL ++ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 127 --AFGTRFRAEFLERRRAALATLVERARQRGDLPAALTAGFAADVVFGVL 174 A + + + ++ + LPA L AA ++ G + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 72.8 bits (178), Expect = 2e-17 Identities = 66/250 (26%), Positives = 101/250 (40%), Gaps = 21/250 (8%) Query: 5 RTTLVVGGTSGIGLAAARRLAAGGDTVHVASRDPGKVAKVADAAPELVAH----RVNGSD 60 + + G GIG A AR LA+ G + +P K+ KV + H + D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 61 SAAVAE----LAGSLAPVDALVVTIASSAGMGPLVDLELAELRRGFEEKVIAMLTVLQAA 116 SAA+ E + + P+D L V +A G + L E F + ++ Sbjct: 69 SAAIDEITARIEREMGPIDIL-VNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 117 LPHLAER--ASITLVGAISAHAAMPGTAGIGAVNAAVESIVRPLAVELAPR--RINAVSP 172 ++ +R SI VG+ A A + AA + L +ELA R N VSP Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 173 GLVDTP-----WWDGMPEQARTDYFAAAEK-GLPVRHVSSADEIGEAVALLATNTS--IT 224 G +T W D + K G+P++ ++ +I +AV L + + IT Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 225 GTILEVDGGA 234 L VDGGA Sbjct: 248 MHNLCVDGGA 257
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.3 bits (112), Expect = 1e-08 Identities = 23/102 (22%), Positives = 42/102 (41%), Gaps = 6/102 (5%) Query: 52 RRRAMAADLIEQAALELFTVRPMDEVTVEQIAAAAGVSVRSFYRYYPGKEMILTALPV-- 109 + I AL LF+ + + ++ +IA AAGV+ + Y ++ K + + + Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 110 --RLATAIAEETARRPPTEAPFAALRNAVDTLTEETNDYLRR 149 + E A+ P P + LR + + E T RR Sbjct: 67 ESNIGELELEYQAKFPGD--PLSVLREILIHVLESTVTEERR 106
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.3 bits (164), Expect = 5e-15 Identities = 32/199 (16%), Positives = 68/199 (34%), Gaps = 11/199 (5%) Query: 227 SPRASATVRQILDAGIQCFAERGYHLSFVDDIVATAGLARGTFYKYFDEKLDLLLALSAE 286 A T + ILD ++ F+++G + + +I AG+ RG Y +F +K DL + Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 287 ASAVSTRLGVEIRGITLGPEGLGRLRGWLSDFVAFHL------RYVGVTRTWIEAAPQDP 340 + + L +E + + L LR L + + + + E + Sbjct: 66 SESNIGELELEYQA-KFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 341 RLDVVRRQVGHEMWADYAALLEQVER----TYPLDLDVAGLVFFCLLERLPDTAVNMAPP 396 + +R + E + L+ L A ++ + L + + Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184 Query: 397 KTPDEAAALLGTVIERGLL 415 + A ++ L Sbjct: 185 FDLKKEARDYVAILLEMYL 203 Score = 60.4 bits (146), Expect = 1e-12 Identities = 21/47 (44%), Positives = 28/47 (59%) Query: 3 AALDLFESQGFHGTSVDEIATAAGVSRATLYQYFESKETIFVELLNE 49 AL LF QG TS+ EIA AAGV+R +Y +F+ K +F E+ Sbjct: 19 VALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.8 bits (69), Expect = 0.007 Identities = 32/155 (20%), Positives = 56/155 (36%), Gaps = 12/155 (7%) Query: 64 AAGVVDEVGAGVEGVSVGDEVFGAAQNASAEYAVLDEWAPKPPELTWAQAAGLAMAVETA 123 AAG ++ + E + +GD ++G + + A + AP P E +A GL Sbjct: 232 AAGALNPFISAGEALGIGDILYGTRY--AIDKAAMRNIAPLPAEGKFAVIGGLGSVAGFE 289 Query: 124 ARGLDLLGITADQELGAGLEAAAGSEQGGSASAGTTLLVNGAAGGVGLAAVQ--LAQARG 181 + D+ + AA E + +A + A G AAV A + Sbjct: 290 KNTRE----AVDRWIQENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGDFADSYK 345 Query: 182 ARVIGTAS----RDNQEYLRSLGVAATDYGPGLVD 212 ++ + S N +Y +L + D D Sbjct: 346 KKLALSDSARQLYQNAKYREALDIHYEDLIRRKTD 380
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 111 bits (278), Expect = 1e-31 Identities = 77/250 (30%), Positives = 126/250 (50%), Gaps = 8/250 (3%) Query: 7 RVAIVTGAARGIGAAIAQRLSRDGLAVAVLDLEEAAAKGTVEAITAAGGRALAVGADVAD 66 ++A +TGAA+GIG A+A+ L+ G +A +D + V ++ A A A ADV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 67 PEQVTAAVAAVTEGLGAPTVLINNAGITRDNLLFKMSEADWDSVIGVHLRGAFLMTRAVQ 126 + A + +G +L+N AG+ R L+ +S+ +W++ V+ G F +R+V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 127 KHMVDAGWGRIVNLSSTSALGNR-GQLNYSTAKAGLQGFTKTAAIELGKFGVTANCIAPG 185 K+M+D G IV + S A R Y+++KA FTK +EL ++ + N ++PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 186 FIASDMTRATAARMGKTWEEYVAASSGV-----IPVGRVGEVDDIAHTVSFFVSEGAGFV 240 +DM + A + E V S IP+ ++ + DIA V F VS AG + Sbjct: 189 STETDMQWSLWAD--ENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 241 SGQIIYVAGG 250 + + V GG Sbjct: 247 TMHNLCVDGG 256
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.021 Identities = 29/193 (15%), Positives = 46/193 (23%), Gaps = 34/193 (17%) Query: 59 GAGGGARVQSPNPAVAA--RYAGLVLEHRATTIADVWDARLLLEPPTAAALARRRTRADL 116 GAGGG + +P+ A G W + R R R L Sbjct: 396 GAGGGEPPKKRDPSAGAGTDPGGPGGGDDGEDPFGEWLDDEVAR-------LRLRGRWLL 448 Query: 117 RALRALLAEHDAATERVQGVRLHNEFHTLVVRLAG-----------NETLALLITLLGEI 165 + RA L E + + G +E V + + + L + Sbjct: 449 KPRRAALIEALRSAPALAGCVAFDELREQPVAVRAFPWRKAPGPLEDADVLRLADYVETT 508 Query: 166 INRTTWTRVEADLGTPELARAER--------------GTVRVHAMLVDLVEAGDATGAQD 211 + + A R R+ LV ++ Sbjct: 509 YGTGEASAQTTEQAINVAADMNRVHPFRDWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPR 568 Query: 212 LWRRHLAAGARYL 224 R G L Sbjct: 569 RLRYLQLVGKYIL 581
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 48.9 bits (116), Expect = 1e-09 Identities = 33/205 (16%), Positives = 67/205 (32%), Gaps = 21/205 (10%) Query: 6 RRPRADARRNRERLLAEADAVFRAQGTNA-SLEGVARRAGVAIGTLYAHFPNRRALLGAL 64 R+ + +A+ R+ +L A +F QG ++ SL +A+ AGV G +Y HF ++ L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 65 LRHRNDALFARGADLLDQPGAAAALTAWVHAVIAHAAAYQGLAAVLAEGVDDEASELH-- 122 + + + + + L + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 123 ---------QACVEMTGIGDRLIARAREAGVLRR----EATGADIFALMN--AAAWIAEQ 167 C+E ++ + EA +L + ++ W+ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 168 MS---AEQAGRLVDLTLAGLLAPPS 189 S ++A V + L L P+ Sbjct: 183 QSFDLKKEARDYVAILLEMYLLCPT 207
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.4 bits (203), Expect = 1e-20 Identities = 66/269 (24%), Positives = 106/269 (39%), Gaps = 31/269 (11%) Query: 21 LRGRAALVTGVSRRAGIGYATARRLAALGATLFLHHYTPHDRDQPWGADPGGPQAVIDGV 80 + G+ A +TG ++ GIG A AR LA+ GA H D + + Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGA-----HIAAVDYNPEK-------LEKVVSS 51 Query: 81 AAARGDGQAAVHHLELDLAVAEAPEQVVNSARDAVGHLDILVCNHARSGGDGPLGTLDAA 140 A A D+ + A +++ +G +DILV A G + +L Sbjct: 52 LKAEARHAEA---FPADVRDSAAIDEITARIEREMGPIDILVNV-AGVLRPGLIHSLSDE 107 Query: 141 MLDAHWAVNTRSTILLAQAFAAQHDGRRGGRIIVMTSGQDLGPMRDEVAYAASKGALASI 200 +A ++VN+ +++ + RR G I+ + S P AYA+SK A Sbjct: 108 EWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMF 167 Query: 201 TRTLADHLADQAITVNAVNPGPVDTG---------YAAPELYAAVRRRF----PRQRWGT 247 T+ L LA+ I N V+PG +T A ++ F P ++ Sbjct: 168 TKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAK 227 Query: 248 PDDPARLVAWLATDDAAWITGQTINTEGG 276 P D A V +L + A IT + +GG Sbjct: 228 PSDIADAVLFLVSGQAGHITMHNLCVDGG 256
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 27.5 bits (60), Expect = 0.021 Identities = 17/48 (35%), Positives = 22/48 (45%) Query: 79 RPTPAGSQALAQGTASWLSLAAVVHPVLVRSLPDPPSATPPESPATPP 126 R T A Q G +WL++ AV PV + D P AT + PP Sbjct: 2 RCTRAIRQTARTGWLTWLAILAVTAPVTSPAWADDPPATVYRYDSRPP 49
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.049 Identities = 38/205 (18%), Positives = 56/205 (27%), Gaps = 28/205 (13%) Query: 41 AGKTTLADELADAVT-RRGRPVVRAGVDGFHQPTHVRRRRGSMSAEGY--FLDAFDYPAL 97 T L D RR PV+ V G +++ RG + AE +L Y Sbjct: 690 WCTTNKRQYLFDITGNRRFWPVL---VPGRANLVWLQKFRGQLFAEALHLYLAGERYFPS 746 Query: 98 RRLLLDPLGPTGDRRYRDACFDHRGDTPLDRPVQRAADDAVLVVDGVFLLRAQLRDCWDL 157 P + R + R L R AA+ A + + DL Sbjct: 747 PEDEEIYFRPEQELRLVETGVQGRLWALLTREGAPAAEGA---AQKGYSVNTTFVTIADL 803 Query: 158 GLFLQISPAESLRRALRRDVTLFGSDAAVRTRYA----------ARYLPAQELYHAQA-- 205 L P +S + + R + P +A Sbjct: 804 VQALGADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGYMRPQVWPPVIAEDKEADQ 863 Query: 206 --APRDHADVLIDNERPDHPVVLRW 228 AP D D ++P P W Sbjct: 864 AHAPGDQ-----DQQQPVEPAAAPW 883
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 1e-05 Identities = 20/197 (10%), Positives = 53/197 (26%), Gaps = 12/197 (6%) Query: 246 AEAVARAVRAEQHARAATAARAEADAVAAEAVTALDDAEARLRAAETARADAVEEAAAAV 305 AEA ++ R + + + E + + + V + + Sbjct: 132 AEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLI 191 Query: 306 RAATAAADAAHADADTAVAAADAQAQAAVDAAHR------------DATARIAEAHADAE 353 + + + + A+ + +R D + + A A+ Sbjct: 192 KEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAK 251 Query: 354 ARLAEATAARDQALADLATARRDGERDARQRTELRAERDALREDIRAERAEALRLRQAAD 413 + E +A+ +L + E+ + + E + + + E + LR Sbjct: 252 HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI 311 Query: 414 ADTQRLRAEATADLDRL 430 A+ Sbjct: 312 GLLTLELAKNEERQQAS 328 Score = 33.6 bits (77), Expect = 0.002 Identities = 21/181 (11%), Positives = 44/181 (24%), Gaps = 8/181 (4%) Query: 340 DATARIAEAHADAEARLAEATAARDQALADLATARRDGERDARQRTELRAERDALREDIR 399 A + A R Q L+ + E + + + Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 400 AERAEALRLRQAADADTQRLRAEATADLDRLRAETAAEITRIRAEAA--------ADVER 451 + E Q + + A+ + A R E + + Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 452 ARAAAAAETERIRAEAEARLDTERRTAAERLAVLGEARAEARARAERAERQADDLAAELR 511 A E E EA L + + + + A+ E + + + + D + Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTT 308 Query: 512 A 512 Sbjct: 309 D 309
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 32.1 bits (73), Expect = 0.002 Identities = 22/108 (20%), Positives = 40/108 (37%), Gaps = 20/108 (18%) Query: 138 TVLVNGASGSVGSAAVQLAVERGARVIGVGSPGT-HDTLRSLGAEPVAYGEGMAERVRAI 196 LV GA+G +G + +E G +V+G+ + +D R+ + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQA------------RLELL 49 Query: 197 TPSGVD-VALDVAGSGVLPELVELAGAPEHVITVADFRGAQQTGVRFS 243 G +D+A + +L +G E V + VR+S Sbjct: 50 AQPGFQFHKIDLADREGMTDLFA-SGHFERVFIS-----PHRLAVRYS 91
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 44.9 bits (106), Expect = 2e-08 Identities = 17/75 (22%), Positives = 29/75 (38%), Gaps = 10/75 (13%) Query: 68 DRTGVDTVELTSLW----------VAPAARGRGVGELLVAAVVEWAERAGADKAVLRVYP 117 + + +++ S W VA R +GVG L+ +EWA+ +L Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 118 SNLHAILLYQRSGFT 132 N+ A Y + F Sbjct: 133 INISACHFYAKHHFI 147
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.1 bits (67), Expect = 0.010 Identities = 18/52 (34%), Positives = 20/52 (38%), Gaps = 4/52 (7%) Query: 194 PMASPPPTTSPGVEPPTGPPA---PSTAPVSPTANDRERFTHRRTGV-GRDG 241 P P P P + P P P T P SP DR HR+ G DG Sbjct: 347 PGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGEDG 398
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 27.6 bits (61), Expect = 0.043 Identities = 15/32 (46%), Positives = 15/32 (46%) Query: 62 ACGGGHVAAAAAPRVRQVVGVDLTPTMLGLAA 93 A G H AAA VVGV P L LAA Sbjct: 174 AAGVAHATPAAAAAEVGVVGVQELPHDLALAA 205
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.0 bits (145), Expect = 2e-13 Identities = 26/168 (15%), Positives = 51/168 (30%), Gaps = 14/168 (8%) Query: 5 GVDAAERLVESTRVLLWERGYVGTSPRAIQAHAGVGQGSMYHHFDGKAALARAAIERTAA 64 + + +++ L ++G TS I AGV +G++Y HF K+ L E + + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 65 ELRAAADAQLGADAPALARV----------EAYLRRERDVLRGCPVGRLTQDPDVMADAE 114 + V R +L + ++ + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 115 LRRPVEQTFTWLRARLGDVLAEGVAAGELV-GLDAAVTAATIVAVLQG 161 +R + R+ L + A L L A + + G Sbjct: 129 AQRNLCLE---SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 28.9 bits (64), Expect = 0.012 Identities = 20/72 (27%), Positives = 27/72 (37%), Gaps = 7/72 (9%) Query: 1 MAGIMVIGLLAGCHSGAGADGPTRADAAARPAPAATTPAPSTP-------APSTPAAAAA 53 +AGI++ LL GC SG + T P+P P P+ P A Sbjct: 10 IAGILIPILLNGCSSGKNKAYLDPKVFPPQVEGGPTVPSPDEPGLPLPGPGPALPTNGAI 69 Query: 54 PTRPAAAAPAAT 65 P APA + Sbjct: 70 PIPEPGTAPAVS 81
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.4 bits (63), Expect = 0.006 Identities = 10/40 (25%), Positives = 20/40 (50%), Gaps = 1/40 (2%) Query: 33 TVNTVASAVLGLVTGAVGAGAASSRVALLVGTGLCGALST 72 T++TV ++V ++ A + V+ LV + G +S Sbjct: 370 TISTVLASVSSGISAAATTSLVGAPVSALV-GAVTGIISG 408
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 34.2 bits (78), Expect = 5e-05 Identities = 13/47 (27%), Positives = 29/47 (61%) Query: 6 DIGTPELLIIIVVVVVLFGAKKLPDAARSLGRSLRIFKSEIKGLHDD 52 DIG ELL++ ++ +V+ G ++LP A +++ +R +S + ++ Sbjct: 3 DIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNE 49
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 30.8 bits (69), Expect = 0.007 Identities = 15/30 (50%), Positives = 18/30 (60%) Query: 260 LLVAVAVLAVLGPQRLAAAGAPLADAVRAA 289 LLV + L VLGPQRL A +A +RA Sbjct: 10 LLVFIIGLVVLGPQRLPVAVKTVAGWIRAL 39
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.8 bits (77), Expect = 7e-04 Identities = 25/103 (24%), Positives = 29/103 (28%), Gaps = 5/103 (4%) Query: 242 AGADPTTGLDASTGASGPGPAGATLPAPHALPAPHTPPAPHLPPALPDPVTPPAPASAWR 301 AG T+ + P T+ AP L P P P P+P P P Sbjct: 30 AGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEP--- 86 Query: 302 WLRTSPPPTHPKLGPGPGTDRAPAVAGEQGIGDADSSGGEPAQ 344 P K P P P EQ D PA Sbjct: 87 --PKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPAS 127
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.6 bits (66), Expect = 0.040 Identities = 20/124 (16%), Positives = 30/124 (24%) Query: 126 RSAPAGGGLTVLSAPATTGGRPAGQGRPLAGAGTAMGPSPRAASTATPDVAVGSEPAATT 185 APA + APA A Q P P P V + Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 102 Query: 186 AGTATTAGAHPPTRSGHDAGPPHTAGTPNTAGTAGARASGSGSGSGSGSGRIILVRIEDC 245 P R + NTA ++ + + S + R Sbjct: 103 PKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSR 162 Query: 246 SRPA 249 ++P Sbjct: 163 NQPQ 166
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.0 bits (62), Expect = 0.046 Identities = 9/63 (14%), Positives = 15/63 (23%), Gaps = 2/63 (3%) Query: 287 TTAPAPLTRPVHWAAPPTPAPPAPAPPIPATPTSATPAATPAATGKPAMRAGRRRGRAGR 346 AP+ P P P P + P + A+ R Sbjct: 86 PPKEAPVVIEKP-KPKPKPKPK-PVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTAT 143 Query: 347 SGS 349 + + Sbjct: 144 AAT 146
>cloacin#Cloacin signature. Length = 551 Score = 35.8 bits (82), Expect = 7e-04 Identities = 34/108 (31%), Positives = 41/108 (37%), Gaps = 16/108 (14%) Query: 364 AGDGGRSRQDATGDGTGPDNRGPDGFGP-----DGRGPHPDDDPDGD----GPHRDGPHR 414 +G GR +G N GP G G DG G +++P G G H G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 415 GGPDGGGPGSGGSDGDDDRTGPGGSLGAGAGLDGQG-PAHGADPATGP 461 G GG SGG +G GG+L A A G PA A G Sbjct: 62 HGNGGGNGNSGGG------SGTGGNLSAVAAPVAFGFPALSTPGAGGL 103
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.3 bits (73), Expect = 0.004 Identities = 19/81 (23%), Positives = 24/81 (29%), Gaps = 4/81 (4%) Query: 419 VAATPSPLVPAGSVLAAHEFHRTVLLPPPAGAPPPAWWLPVVDPAAPASAGAATPPPQAP 478 V P+P P + A L PP A PPP + P P Sbjct: 40 VIELPAPAQPISVTMVA----PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIE 95 Query: 479 PGTPPAAVEPPVAGPIEAPSR 499 P +P +E P R Sbjct: 96 KPKPKPKPKPKPVKKVEQPKR 116
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 67.5 bits (165), Expect = 1e-15 Identities = 39/183 (21%), Positives = 60/183 (32%), Gaps = 22/183 (12%) Query: 1 MRVLVTGDRGLVGRAVTAALTSAGHRTVGFD-LMDGHDV------CDAAGLERMSAGCGG 53 M+ LVTG G +G V+ L AGH+ VG D L D +DV + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 54 IVHLAALDEPVDDPG------LAAFGPVTTG-TDTRVF-ETNVVGTSNVLRAAERRGVPR 105 + + + V + + ++N+ G N+L + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 106 VVVMSSVDVLGCFGGRGRPAYLPLDDRHPA-RPAGAYAMSKWLAEQMCQVATAATGLCTV 164 ++ SS V G +P P YA +K E M + GL Sbjct: 121 LLYASSSSVY------GLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPAT 174 Query: 165 CLR 167 LR Sbjct: 175 GLR 177
>PERTACTIN#Pertactin signature. Length = 922 Score = 27.8 bits (61), Expect = 0.036 Identities = 20/73 (27%), Positives = 22/73 (30%) Query: 40 YGDAGAPGGYDGPYGQPAGGPVAPWQGQPYGGAYPPTGGAYPPPGGYPIGPPQPFPTTGA 99 Y A G G A P P PP P PPQ P A Sbjct: 550 YRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPA 609 Query: 100 PGPLAPQKSVAVA 112 P P A ++ A A Sbjct: 610 PQPPAGRELSAAA 622
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 40.2 bits (94), Expect = 3e-05 Identities = 29/153 (18%), Positives = 53/153 (34%), Gaps = 31/153 (20%) Query: 38 RVFVTGVTGFMGEALLERLLSDFPDTSVVALVRPRGSHT-GVARLARMTRKPAFRQLRER 96 + VTG GF+G + +RLL G G+ L + +Q R Sbjct: 2 KYLVTGAAGFIGFHVSKRLLE-------------AGHQVVGIDNLNDY-YDVSLKQAR-- 45 Query: 97 LGAAGLAELVARRVEVVEGDLSRLPAL-----PGDIDVVIHCAGEVSFDPPIDDG---FR 148 L L + + DL+ + G + V ++ +++ Sbjct: 46 -----LELLAQPGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD 100 Query: 149 INVGGLQELLRALAAAGARPHLVHVSTAYVAGL 181 N+ G +L + HL++ S++ V GL Sbjct: 101 SNLTGFLNILEGCRHNKIQ-HLLYASSSSVYGL 132
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.5 bits (68), Expect = 0.014 Identities = 26/85 (30%), Positives = 39/85 (45%), Gaps = 8/85 (9%) Query: 105 AGVSAPGGAVVGDAAAGRVGAGGDGAAGGEVEEVADELTVQLPIIDAVLDAFGIARAAAA 164 AG + PGGAV G A G G DG G +V + +L ++++A + A A Sbjct: 265 AGGAVPGGAVPGGAVPGGFGPLLDGWYGVDVSDSTVDLA------QSIVEAPQLGAAIRA 318 Query: 165 GFEADDVIA--TLATRHGGGARGGG 187 G A ++ +L+ HG GG Sbjct: 319 GRGARVTVSGGSLSAPHGNVIETGG 343
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.4 bits (81), Expect = 4e-04 Identities = 22/80 (27%), Positives = 29/80 (36%), Gaps = 10/80 (12%) Query: 9 VSKWFADGQVAVDDVSLRVADGELLILVGPSGCGKSTTLNMIAGLEDISDGELRIGGRVV 68 V K+ G VA D ++L G G GKST +N + GL+ SD IG Sbjct: 576 VGKYILMGHVARVMEPGCKFDY-SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG---- 630 Query: 69 NGLGPAERDVAMVFQSYALY 88 +D Y Sbjct: 631 -----TGKDSYEQIAGIVAY 645
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 41.6 bits (97), Expect = 3e-06 Identities = 21/50 (42%), Positives = 28/50 (56%) Query: 97 WRGRLYAAPLNTNAQLLWYRKDLVARPPATWAQMLAQAKALAAAGKPHLV 146 + G+L A P+ A L Y KDL+ PP TW ++ A K L A GK L+ Sbjct: 125 YNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALM 174
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.3 bits (73), Expect = 0.004 Identities = 19/97 (19%), Positives = 23/97 (23%), Gaps = 2/97 (2%) Query: 3 PTPATPSPTAQAAGDTAATPTPPATVPAQPRTGVEPPRGSDPPPLAPAATSTEPGQPGGE 62 P P +A P P + +P R P PA+ Sbjct: 79 EPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPT 138 Query: 63 QPAQDRATGDRAARRTRRRATLRRRTP--PALAALLG 97 AT L R P PA A L Sbjct: 139 SSTATAATSKPVTSVASGPRALSRNQPQYPARAQALR 175
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 34.1 bits (78), Expect = 1e-04 Identities = 21/77 (27%), Positives = 31/77 (40%), Gaps = 12/77 (15%) Query: 30 ELSPQRYAILRQAATEPPFTGAYTYSKETGTYRCGGCGAALFTSDTKYDSGSGWPSFTEP 89 E+S + L+Q+ T PP + + T+R GAA T D KY+ + Sbjct: 189 EISS--FGQLKQSITLPPHLDTGSSNFALHTFR----GAAYSTPDEKYE------KYKFD 236 Query: 90 AVADAVELVEDRSHGMV 106 +AD L G V Sbjct: 237 TIADNENLNISSKGGWV 253
>PF07132#Harpin protein (HrpN) Length = 356 Score = 32.4 bits (73), Expect = 0.008 Identities = 23/71 (32%), Positives = 29/71 (40%), Gaps = 2/71 (2%) Query: 759 LLGELDGPGAGVGLGAGVGLGAGVGLGVGSAGGDGPVFDAAGWEQALAGYYAE--HDEIG 816 L G L G G G GLG+ +G G G LG G G G +A + D +G Sbjct: 83 LGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGAGMNAMNPSAMMGSLLFSALEDLLG 142 Query: 817 TGPDARGPGLL 827 G + GL Sbjct: 143 GGMSQQQGGLF 153
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 2e-14 Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 4/120 (3%) Query: 1 MSTVRVFLLDDHEIVRRGIREMLSETG-DVDVVGEASTAAEALRRIPATRPNVAVLDARL 59 M+ + + DD +R + + LS G DV + A+T + ++ V D + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD---GDLVVTDVVM 57 Query: 60 EDGNGIDVCRDLRSAHPEIGCLILTSYDDDDALFAAIMAGAAGYLLKQIKGTDLVGAIRT 119 D N D+ ++ A P++ L++++ + A GA YL K T+L+G I Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>YERSINIAYOPE#Yersinia virulence determinant YopE protein signature. Length = 219 Score = 31.2 bits (70), Expect = 0.009 Identities = 19/83 (22%), Positives = 29/83 (34%) Query: 37 GGACRSAQVTAPGFVSDLFSAFHPFAAASPALRRLDLPAQGLEWCRAPQVLAHPTPDGRC 96 S + GF+ +FS +PA +P+ Q+ A P Sbjct: 60 IERLSSVAHSVIGFIQRMFSEGSHKPVVTPAPTPAQMPSPTSFSDSIKQLAAETLPKYMQ 119 Query: 97 ALLSMDPARTARSLDDFAAGDGA 119 L S+D ++ D FA G G Sbjct: 120 QLNSLDAEMLQKNHDQFATGSGP 142
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 3e-05 Identities = 19/81 (23%), Positives = 36/81 (44%), Gaps = 7/81 (8%) Query: 17 QAVLIAEVDGVVVG--TLIAGWDGWRCHLYRLAVAPEHRRAGIARALLAAARE--RFLAL 72 +A + ++ +G + + W+G + +AVA ++R+ G+ ALL A E + Sbjct: 65 KAAFLYYLENNCIGRIKIRSNWNG-YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHF 123 Query: 73 GGRRIDAMVDDTNTQAHALYR 93 G ++ D N A Y Sbjct: 124 CGLMLE--TQDINISACHFYA 142
>PF08280#M protein trans-acting positive regulator Length = 530 Score = 31.0 bits (70), Expect = 0.009 Identities = 9/67 (13%), Positives = 28/67 (41%), Gaps = 3/67 (4%) Query: 142 IDVKVLRGAWSGKDAQVRLLSAMLHGKGAVRVRVRIPDDTNEITHIQELVTKLPKNARPT 201 ++K+ + G++ ++R L A+L+ K ++V + I ++ + + + Sbjct: 166 FELKLSKNKIVGEEYRIRYLIALLYSKFGIKV---YDLTQQDKNIIHSFLSHSSTHLKTS 222 Query: 202 SHDARRH 208 + Sbjct: 223 PWLSESF 229
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 59.9 bits (145), Expect = 4e-11 Identities = 59/297 (19%), Positives = 111/297 (37%), Gaps = 39/297 (13%) Query: 147 DGHTAIVSVLMK----DAPTTPDLPAMRRLIATARDYDAPDLQVEVTGPATTVVVQGTIS 202 +G A + +A T A++ +A + + ++V TT VQ +I Sbjct: 282 NGKPAAGLGIKLATGANALDTAK--AIKAKLAELQPFFPQGMKVLYPYD-TTPFVQLSIH 338 Query: 203 PWPIAIGIGVALLILCLAV--RSPAAVAVCAVAAGAATAGALAAVTLLSHRANVMQLATL 260 + + L+ L + + ++ A + +A G A + + N + T+ Sbjct: 339 EVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTL---TM 395 Query: 261 LALVLGFGLSLGSALVVVNRCQTDLRRGRG-PADAVRAAMRHPGRATVAGSLGLAVVMLG 319 +VL GL + A+VVV + + + P +A +M A V ++ L+ V + Sbjct: 396 FGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIP 455 Query: 320 TSALRLS---VFDGLALAGFTAAAVSILVVVTLLPAMLAI-----------SGRGLLVWA 365 + S ++ ++ +A A+S+LV + L PA+ A + G W Sbjct: 456 MAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWF 515 Query: 366 ERT-HLSVTGTGLPVRPGLRSWWAGTVGRHPQVLAGAAVVLLTVLALPVVGLRLGGT 421 T SV V L S + + L V + V+ LRL + Sbjct: 516 NTTFDHSVNHYTNSVGKILGSTGRYLL-----------IYALIVAGMVVLFLRLPSS 561 Score = 36.4 bits (84), Expect = 6e-04 Identities = 30/168 (17%), Positives = 71/168 (42%), Gaps = 20/168 (11%) Query: 556 LILELGVLGVAVLLGLRSVRHSLAITAASMLALAATMGVITSVFCNGWLASGLGVRTGPI 615 L + ++ + + L L+++R +L T A + L T ++ + T Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILA------AFGYSINTLT--- 394 Query: 616 EPFILGLILIIVYGLSIGMHLTLLNRL-RGSADA-ADPQAEVSSRHADVGGVVITISMIM 673 + G++L I GL + + ++ + R + P+ + + G ++ I+M++ Sbjct: 395 ---MFGMVLAI--GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVL 449 Query: 674 VAVFV---ALTTQQVRMMKLLGIGLSVGVILDALVLRLVLLPALIHLV 718 AVF+ + + I + + L ++++ L+L PAL + Sbjct: 450 SAVFIPMAFFGGSTGAIYRQFSITIVSAMAL-SVLVALILTPALCATL 496
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 113 bits (283), Expect = 3e-29 Identities = 80/399 (20%), Positives = 146/399 (36%), Gaps = 23/399 (5%) Query: 22 VAMSNLDLFVVNVALPDVGRHFDGSSLSSLSWVLNGYAVVFAALLVPAGNLADRTSPRRA 81 S L+ V+NV+LPD+ F +S +WV + + F+ G L+D+ +R Sbjct: 23 SFFSVLNEMVLNVSLPDIANDF-NKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRL 81 Query: 82 YLWGIGIFVAASALCAVAPAVWF-LVAARVLQAAGAAVMTPSSLGLLLAAAPPERRGAAV 140 L+GI I S + V + + L+ AR +Q AGAA + ++ P E RG A Sbjct: 82 LLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 141 RAWTAVSGLAAALGPVAGGLLTELDWRWVFLVNLPVGLAVLVAGPRVLPHLPRRPGAGRT 200 ++ + +GP GG++ W +L+ +P+ + V L + Sbjct: 142 GLIGSIVAMGEGVGPAIGGMIAHY-IHWSYLLLIPMITIITVPFLMKLL----KKEVRIK 196 Query: 201 ---DLAGAVVLTVGIAALALGLVRGPDWGWGSARIVGSLLAGVLLLAGFLHRSARHPAPV 257 D+ G ++++VGI L + L+ VL F+ + P Sbjct: 197 GHFDIKGIILMSVGIVFFMLF-TTSYSISF--------LIVSVLSFLIFVKHIRKVTDPF 247 Query: 258 LPLPLLRVRTFSAAAVAAFVFSVAFAAMLLSAVLWCQDGWHWSALRTG-LAIAPGPLMVP 316 + L + F + + A + +D S G + I PG + V Sbjct: 248 VDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVI 307 Query: 317 GLALAAGPLVARLGPGRVAAGGCGVFAAGIGWWILRMAPQPDYVGAMLPGMLLTGVGVGL 376 G LV R GP V G + + + + M ++ G+ Sbjct: 308 IFGYIGGILVDRRGPLYVLNIGVTFLS--VSFLTASFLLETTSW-FMTIIIVFVLGGLSF 364 Query: 377 ILPTLISAAVTALPPASFSTGSAVVTMARQIGTVIGTAL 415 + + ++L G +++ + G A+ Sbjct: 365 TKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>PF06580#Sensor histidine kinase Length = 349 Score = 27.5 bits (61), Expect = 0.016 Identities = 15/92 (16%), Positives = 32/92 (34%), Gaps = 15/92 (16%) Query: 30 RARQRLTADLTGRGVPAEVTETVL--LLASELVTNAVLHG------HGEPVVEIRTTDDL 81 + RL + + + + + +L LV N + HG G+ +++ + Sbjct: 235 QFEDRLQFENQ---INPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGT 291 Query: 82 VWVGVRDPDRRRPQVRHVDADSLGGRGLHLVD 113 V + V + + + G GL V Sbjct: 292 VTLEVENTGSLALK----NTKESTGTGLQNVR 319
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 30.2 bits (68), Expect = 0.011 Identities = 10/28 (35%), Positives = 14/28 (50%) Query: 387 GCFDVVHAGHIAYLHAARHLGDILVVAV 414 G FD + GH+ + L D + VAV Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAV 34
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 66.6 bits (162), Expect = 4e-15 Identities = 63/235 (26%), Positives = 87/235 (37%), Gaps = 31/235 (13%) Query: 35 VLVSGGASGLGAAVVAAVRDAGGTPLVLDRFPVP-------------SAEHAIVDLADGR 81 ++G A G+G AV + G +D P AE D+ D Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 82 ATELATRRLVERAGGRLDGVFTAAGTDRPAPFGSLDGAGWERIVGVNLLGTAAVIRGALP 141 A + T R+ ER G +D + AG RP SL WE VN G R Sbjct: 71 AIDEITARI-EREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 142 YLEA-SAGRIVTCASTLGLRVAGDASAYCASKFGVVGFTRALAEEFRGR-LGVTLLVPGG 199 Y+ +G IVT S +AY +SK V FT+ L E + ++ PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 200 MTTAF------FDDREEQYKPG---------PDAKLNRPEDVARTVLFALTQPPG 239 T ++ EQ G P KL +P D+A VLF ++ G Sbjct: 190 TETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 115 bits (289), Expect = 5e-30 Identities = 86/412 (20%), Positives = 165/412 (40%), Gaps = 28/412 (6%) Query: 26 IMGILDGSMVAVGVDTLAARFDAALSTIGWVSTGYLLALTVAIPVTTWAVDRFGARRLWL 85 +L+ ++ V + +A F+ ++ WV+T ++L ++ V D+ G +RL L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 86 AGLVAFLAASVASGLAWNVSSLIVF-RVLQGLAAGILDPLVLTLLARAAGPRRAGRVMGL 144 G++ SV + + SL++ R +QG A LV+ ++AR G+ GL Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 145 MGMVLSAGPVLGLIVGGAVLAHLSWRWMFLINLPIGAVALIGALRVIPRDAPAGDPSAGE 204 +G +++ G +G +GG + ++ W +L+ +P+ + + L + + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKK--------EV 193 Query: 205 VARTRLDVLGVALVGPGFAAAVLALSQAADRTTFAAWQVLVPLAAAVALLAGYVGHALRP 264 + D+ G+ L+ G +L TT + L+ +V +V H + Sbjct: 194 RIKGHFDIKGIILMSVGIVFFMLF-------TTSYSISFLI---VSVLSFLIFVKHIRKV 243 Query: 265 ADARRPPPLIDVRLFTSGGFSASVTIMMLVGLAMFANLFVLPLYYQQQHGHGPLASGLLV 324 D P +D L + F V ++ + + ++P + H G ++ Sbjct: 244 TD-----PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 325 S-PFAIAAIIAMPQSGRLSDRLGARRLVRAGALVAAVGEFAFTRVGAHTAEVWPALAAFV 383 P ++ II G L DR G ++ G +V F T + + Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVF 357 Query: 384 VGLGLSFVGAPTMGSLYRTLPPALVPQGSSVLYILNQLGAAIGIAVVTLILA 435 V GLSF + +L G S+L + L GIA+V +L+ Sbjct: 358 VLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409 Score = 31.8 bits (72), Expect = 0.007 Identities = 23/100 (23%), Positives = 44/100 (44%), Gaps = 2/100 (2%) Query: 339 GRLSDRLGARRLVRAGALVAAVGEFAFTRVGAHTAEVWPALAAFVVGLGLSFVGAPTMGS 398 G+LSD+LG +RL+ G ++ G H+ +A F+ G G + A M Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVI--GFVGHSFFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 399 LYRTLPPALVPQGSSVLYILNQLGAAIGIAVVTLILATVG 438 + R +P + ++ + +G +G A+ +I + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH 167
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 6e-12 Identities = 37/205 (18%), Positives = 68/205 (33%), Gaps = 11/205 (5%) Query: 26 APPGARGRIDKRNAILATAFVVFAREGYTQATLDAIAAEARVAKHTIYNHFGDKQTLLRA 85 A + + R IL A +F+++G + +L IA A V + IY HF DK L Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 86 AIAAEADRAMAKNLAAVDRLRDHDGDLRAALEDVGSQLVACYCDERGW-ALRRLLYAEIN 144 ++ GD + L ++ ++ E L +++ + Sbjct: 62 IWELSESNIGE---LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 145 QFPDLLDIITGRASDP--VTEALADRLARLALAGHLRAG-DPAAAAEQLAALLTGSLEAR 201 ++ + + + + + L A L A AA + ++G +E Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 202 CRYGTRVISPAEQHAVARAAVDTFL 226 E AR V L Sbjct: 179 LFAPQSFDLKKE----ARDYVAILL 199
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 48.5 bits (115), Expect = 2e-08 Identities = 32/189 (16%), Positives = 66/189 (34%), Gaps = 39/189 (20%) Query: 51 GDGLGSGIVYRSNGVIVTNQHVVASAAGGAVEVAFA----------DGRRVPGKVQAADA 100 G + SG+V + ++TN+HVV + G + +G ++ Sbjct: 100 GTFIASGVVVGKD-TLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158 Query: 101 ISDIAVVKVERTGLPAAKFREQQPRLGELAIAIGSPLGLENSVTAGIISGVNRTLPGVDG 160 D+A+VK P + + + ++ + + ++T Sbjct: 159 EGDLAIVKFS----PNEQNKHIGEVVKPATMSNNAETQVNQNITVT-------------- 200 Query: 161 QGGPGGDGGQGGSGGSGGQGGSGGQAAAAGPRVDLIQTDAAISPGNSGGPLLDAEGRVVG 220 G G S G+ + + +Q D + + GNSG P+ + + V+G Sbjct: 201 --------GYPGDKPVATMWESKGKITYL--KGEAMQYDLSTTGGNSGSPVFNEKNEVIG 250 Query: 221 VTEAYVPPQ 229 + VP + Sbjct: 251 IHWGGVPNE 259
>cloacin#Cloacin signature. Length = 551 Score = 39.7 bits (92), Expect = 3e-05 Identities = 31/115 (26%), Positives = 41/115 (35%), Gaps = 13/115 (11%) Query: 519 HTGSIPTSGPSSAATGGGPGGGGGRFGAGSPPTGNPPTGTRPTGTGTGTAGSSAAASTTS 578 +TG+ TSG + G GGG G+G NP G +G G Sbjct: 10 NTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 579 GTAGGSTSAPEGVAAGGGGGEQSTNAALT----ALLARSTTTWAAATTGGATSAA 629 + GGS G GG + A + AL A + + GA SAA Sbjct: 70 NSGGGS---------GTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAA 115 Score = 33.9 bits (77), Expect = 0.002 Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 5/52 (9%) Query: 308 GSSGGGAGGGAGGGGGGGGMGGGANNGFGGATGIIRLFGSSMGSEISWLLPA 359 G SG G G G G G GG G + G G S++ + +++ PA Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN-----LSAVAAPVAFGFPA 94 Score = 33.5 bits (76), Expect = 0.003 Identities = 27/103 (26%), Positives = 35/103 (33%), Gaps = 5/103 (4%) Query: 503 VGAGSAAYAASTAAHPHTGSIPTSGPSSAATGGGPGGGGGRFGAGSPPTGNPPTGTRPTG 562 + G A +G + P +G G GG G+G G G G Sbjct: 20 INGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGG---GSGHGNGGG--NGNSGGG 74 Query: 563 TGTGTAGSSAAASTTSGTAGGSTSAPEGVAAGGGGGEQSTNAA 605 +GTG S+ AA G ST G+A G S A Sbjct: 75 SGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIA 117 Score = 30.8 bits (69), Expect = 0.020 Identities = 20/61 (32%), Positives = 22/61 (36%) Query: 286 GGSTDNSLLQLALGYNGLGRILGSSGGGAGGGAGGGGGGGGMGGGANNGFGGATGIIRLF 345 GG++D S G G G GG G GGG G GG G A F Sbjct: 31 GGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAF 90 Query: 346 G 346 G Sbjct: 91 G 91
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 71.9 bits (176), Expect = 1e-17 Identities = 44/203 (21%), Positives = 81/203 (39%), Gaps = 5/203 (2%) Query: 1 MRALGVDDIVAAALRVGTHRGFEALTMRALAEELGVSAMAAYHHVPSKDALVD-LVIDAV 59 M L + ++ AAL + G + LT R LA++LG+ Y HV +K AL+D L ++ + Sbjct: 1 MARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEIL 60 Query: 60 LADVEIPPPDLG-DWDVRLCELRRRSAAALEAWPGVDVLVYARPPTTQGWRIMDGYLQIL 118 + P G W L AL + + P + + ++ L+ + Sbjct: 61 ARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFM 120 Query: 119 LDAGLTPKNALLGFNVLHDYGMARSIQRRLHEGAGAGVPGDRSAQWPALSRVEAMWSQVH 178 + G + ++ L + + + + ++++ H A P P L R EA+ Sbjct: 121 TENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDENLPPLLR-EALQIMDS 179 Query: 179 GSDLTAFADTL--VVDGLRALLA 199 AF L ++ G L Sbjct: 180 DDGEQAFLHGLESLIRGFEVQLT 202
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 103 bits (257), Expect = 2e-25 Identities = 83/400 (20%), Positives = 143/400 (35%), Gaps = 37/400 (9%) Query: 35 VLMATVNSSIVIISLPAIFRGIHLDPLQPGNVSYLLWMLMGYMLVSAVLVVTLGRLGDMF 94 + +N ++ +SLP I + P + W+ +ML ++ G+L D Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPP------ASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 95 GRVRIYNAGFAVFSVASVGLALTPWQGSSGALWLIGWRVVQGVGGAMLMANSTAILTDAF 154 G R+ G + SV + G S LI R +QG G A A ++ Sbjct: 77 GIKRLLLFGIIINCFGSVIGFV----GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYI 132 Query: 155 PTRQRGMALG-INQVAALAGSFVGLVAGGLLSEWNWRAVFWVSVPIGVAGTIWSYRSLRD 213 P RG A G I + A+ + G + +W + + +P+ T+ L Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLK 190 Query: 214 TGRRAPARIDWWGNITFAVGLTALLAGVTYGIQPYGGHDMGWLNPKVLAALIGGAAVLVA 273 R D G I +VG+ + T + + +L VL+ LI Sbjct: 191 KEVRIKGHFDIKGIILMSVGIVFFMLFTT-------SYSISFLIVSVLSFLI-------- 235 Query: 274 FVLIERRTAQPMFNLALFRIRAFTAGNAAVLLSSIARGGMQFMLIIWLQGIWLPLHGYDY 333 FV R+ P + L + F G + G M+ ++ + H Sbjct: 236 FVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV----HQ--- 288 Query: 334 VDTPLWAGVYLLPLTVGFLVAGPVSGFLSDRFGARAFATGGLTLVAATFVGLLLLP-TNF 392 + T V + P T+ ++ G + G L DR G G+T ++ +F+ L T Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTS 348 Query: 393 SYPAFAVLLVLNGIGSGLFSAPNTTAVMNAVPAAARGGAS 432 + ++ VL G+ +T + A G S Sbjct: 349 WFMTIIIVFVLGGLSFTKTVI-STIVSSSLKQQEAGAGMS 387
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 34.4 bits (79), Expect = 2e-04 Identities = 22/125 (17%), Positives = 38/125 (30%), Gaps = 22/125 (17%) Query: 1 MHLAVFGGTGHTGRHLLEQALAQGHTV-----------TALARDPRGLATHERLRPVAGD 49 M V G G G H+ ++ L GH V +L + L + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 50 VRDAAVVKQVI-----------AGSDAVLSALGQRRWGSTVCTDGMRTILPAMQDHGVER 98 + D + + AV +L + G IL + + ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 99 LIAVS 103 L+ S Sbjct: 121 LLYAS 125
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 41.5 bits (97), Expect = 4e-07 Identities = 21/139 (15%), Positives = 44/139 (31%), Gaps = 10/139 (7%) Query: 2 SMVAVAARARASKATIYRRWSCKDEMVVEALRRHGP--ADHVPADTGCLRDDVAAEVRLM 59 S+ +A A ++ IY + K ++ E + D + +R + Sbjct: 33 SLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREI 92 Query: 60 ID-----TASGPGGALLVGVLRAASESPRLAAVI---QANILQRKVELGRCLLERAAQRG 111 + T + LL+ ++ E AV+ Q N+ + L+ + Sbjct: 93 LIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAK 152 Query: 112 ELLAKTEPAVLVEVILAMI 130 L A ++ I Sbjct: 153 MLPADLMTRRAAIIMRGYI 171
>cloacin#Cloacin signature. Length = 551 Score = 28.9 bits (64), Expect = 0.016 Identities = 18/68 (26%), Positives = 22/68 (32%) Query: 135 GRASSRGGAAGSASAAAGGGPAPGVGAATATTTPGAGIAAVPGGSASTAPAADAHDGGGG 194 G A S S GGP A+ G P G S + G G Sbjct: 4 GDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63 Query: 195 DGGGVGGA 202 +GGG G + Sbjct: 64 NGGGNGNS 71
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 31.2 bits (70), Expect = 0.016 Identities = 19/65 (29%), Positives = 23/65 (35%), Gaps = 1/65 (1%) Query: 817 LSAAASRGELAAARRPSVTQSNVRTLPAPSAPPALSALSAPGAGPAAPSAGPGTGDTPDA 876 L S G+ A P V V P +P L PG GPA P+ G P Sbjct: 18 LLNGCSSGKNKAYLDPKVFPPQVEGGPTVPSP-DEPGLPLPGPGPALPTNGAIPIPEPGT 76 Query: 877 RDEVT 881 V+ Sbjct: 77 APAVS 81
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 5e-04 Identities = 46/155 (29%), Positives = 57/155 (36%), Gaps = 17/155 (10%) Query: 175 LGSLLLVADVTGSYGQAGAVSATLALAGALAGPVISRLIDRAGARRVLLVLTGLHVLAGA 234 L L+ DVT YG + A AL PV+ L DR G R VLLV LAGA Sbjct: 32 LRDLVHSNDVTAHYG---ILLALYALMQFACAPVLGALSDRFGRRPVLLV-----SLAGA 83 Query: 235 VFGFVVLVRASTAMVLAA----AALTGATLPQVGAVARERWATLLAGSPTLQSAYALESV 290 + ++ A VL A +TGAT GA + + + S Sbjct: 84 AVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD-----ITDGDERARHFGFMSA 138 Query: 291 LDEVAFALGPAAAGLLAGALPPAGLIAALACAATA 325 GP GL+ G P A AA A Sbjct: 139 CFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLN 173
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.2 bits (135), Expect = 5e-12 Identities = 39/202 (19%), Positives = 70/202 (34%), Gaps = 22/202 (10%) Query: 6 RRTGRRPATSAAELEHLALQIFTERGFEETTVDDIARAAGIGRRTFFRYFASKNDVPWGD 65 R+T + + + +AL++F+++G T++ +IA+AAG+ R + +F K+D+ Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 66 FDGQLEVMRASLASAAAGEP--TVAVLRRAILDFNTYPPAEGAWLRRRMTLILRTPALQA 123 ++ + A P ++VLR ++ E RR + I+ Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER--RRLLMEIIFHKCEFV 120 Query: 124 HSTLRYASWRGVLAEFV----------ARRVGQPADALTPQAVAAAHLGVAVTAYEQWLR 173 + L L + A G E WL Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 174 --------EEGTDLVAILDEAL 187 +E D VAIL E Sbjct: 181 APQSFDLKKEARDYVAILLEMY 202
>cloacin#Cloacin signature. Length = 551 Score = 28.1 bits (62), Expect = 0.002 Identities = 18/42 (42%), Positives = 18/42 (42%), Gaps = 4/42 (9%) Query: 29 GWGGG---WGGWSGWG-GWGGWGWSRWGRGGGWGGWGGWGGG 66 GW WGG SG G WGG G G G G G GG Sbjct: 38 GWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79 Score = 27.0 bits (59), Expect = 0.006 Identities = 17/37 (45%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 30 WGGGWGGWSGWGGWGGWGWSRWGRGGGWGGWGGWGGG 66 WGGG G WGG G G G G GG G GG Sbjct: 46 WGGGSGSGIHWGGGSGHGNG--GGNGNSGGGSGTGGN 80 Score = 24.7 bits (53), Expect = 0.040 Identities = 22/52 (42%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 21 GFVGFFVGGWGGGWGGWSG----WGGWGGWGWSRWGRGGGWGGWGGWGGGWG 68 G G VGG GWS WGG G G WG G G G GG G G Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSG-IHWGGGSGHGNGGGNGNSGG 73
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 44.4 bits (105), Expect = 3e-07 Identities = 37/191 (19%), Positives = 60/191 (31%), Gaps = 44/191 (23%) Query: 126 EGEGDFLPVGEMILA-GTGFRSEPAAHAEAARVLGRPVHSLTLV-------DPRFYHLDT 177 EG GD L + + +L G R+E + + A L + S + + + HLDT Sbjct: 217 EG-GDELVLNKGLLVIGISERTEAKSVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDT 275 Query: 178 ALCVLDDDLVAYLP--------------------------AAFDDAARRRLATLFPDAIR 211 +D + A D L D I+ Sbjct: 276 VFTQIDYSVFTSFTSDDMYFSIYVLTYNPSSSKIHIKKEKARIKDVLSFYLGRK-IDIIK 334 Query: 212 VSEADAAVFGLNAVSDGRHVVLSAAAEGFAAD--------LRTRGFEPIGVEFDELRRGG 263 + D +DG +V+ A E A G + + EL RG Sbjct: 335 CAGGDLIHGAREQWNDGANVLAIAPGEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGR 394 Query: 264 GGIKCATLEIR 274 GG +C ++ + Sbjct: 395 GGPRCMSMPLI 405
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 33.2 bits (75), Expect = 0.004 Identities = 17/34 (50%), Positives = 23/34 (67%), Gaps = 1/34 (2%) Query: 121 SHAHIRGVLHLDIKPGNLLFD-AAGTLKVADFGI 153 +H GV+H DIKPGN++FD A+G V D G+ Sbjct: 259 NHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGL 292
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.8 bits (77), Expect = 4e-04 Identities = 13/55 (23%), Positives = 20/55 (36%), Gaps = 3/55 (5%) Query: 161 AVCTDEAHRGQGLATRLVHAVAAIIRARGETPF-LHASADNTGAIRLYEQLGFRL 214 AV D +R +G+ T L+H + L N A Y + F + Sbjct: 96 AVAKD--YRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.4 bits (94), Expect = 2e-06 Identities = 25/122 (20%), Positives = 43/122 (35%), Gaps = 11/122 (9%) Query: 3 NRALVVIDVQREYEEGALPIAYPPLTESLASIGRAMDAARHRGVPIAVIQQDAPAT---- 58 NRA+++I + Y A P+TE A+I + + G+P+ Q Sbjct: 29 NRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDDR 88 Query: 59 ---SPIFAVGTTGWQLHPVVADR----PSDTLFTKRLPGAFTGTGLERWLRERAVDTVTL 111 + + G + D + TK AF T L +R+ D + + Sbjct: 89 ALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLII 148 Query: 112 VG 113 G Sbjct: 149 TG 150
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 77.7 bits (191), Expect = 5e-18 Identities = 46/112 (41%), Positives = 58/112 (51%), Gaps = 12/112 (10%) Query: 279 VTFPVSGARLSPSAQARLDSVAAVLR---GGDLAVLVGGYTDTSGPSALNQALSLNRAQA 335 V F + A L P QA LD + + L D +V+V GYTD G A NQ LS RAQ+ Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 336 AADYLTSRGVPADLVRAAGFGSREPVAGNGTPQGR---------AANRRIEI 378 DYL S+G+PAD + A G G PV GN + A +RR+EI Sbjct: 281 VVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 31.9 bits (72), Expect = 0.004 Identities = 11/58 (18%), Positives = 13/58 (22%) Query: 381 AASPLSPEPLEPPVEPTAAPPTPPAEPASSTRAAPVTGRQGPPSAAPVPPVPAPAAPE 438 + L P P P P EP + P P P E Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQE 108 Score = 31.5 bits (71), Expect = 0.005 Identities = 18/84 (21%), Positives = 21/84 (25%), Gaps = 6/84 (7%) Query: 371 PAAGPGAAAGAASPLSPEPLEPPVEPTAAPPTPPAEPASSTRAAPVTGRQGPPSAAPVPP 430 PA A P EP EP PP + P P PV Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP------KPKPKPVKK 105 Query: 431 VPAPAAPEISLRSDRAVRPDGARA 454 V ++ R P A Sbjct: 106 VQEQPKRDVKPVESRPASPFENTA 129
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.9 bits (64), Expect = 0.016 Identities = 17/45 (37%), Positives = 20/45 (44%) Query: 134 ADPPPTGSSPTGSSPTGSSPTGSSPTGSSMSGSSASGSSASGSSV 178 D P G+ P G+ P G+ P G P G G SGSSV Sbjct: 261 GDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSV 305 Score = 28.1 bits (62), Expect = 0.029 Identities = 16/42 (38%), Positives = 18/42 (42%) Query: 132 PAADPPPTGSSPTGSSPTGSSPTGSSPTGSSMSGSSASGSSA 173 PA P G+ P G+ P G P G P G SGSS Sbjct: 264 PAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSV 305
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 30.0 bits (67), Expect = 0.025 Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 19/108 (17%) Query: 250 YLNQRELDERRRKRERANAEKKIDSLKAQADKMRAKATKARAAHQMDRRAERLAAGLADV 309 YLN+ +L +K E + K++S KA + A KA + ++D++ L G+ Sbjct: 54 YLNKPDLGAFAQKEETNSKITKLESSKADKN---AVYLKAESKIELDKKLN-LKGGVM-- 107 Query: 310 RVADRVAKLRFPDPAPCGRTPLTASG------LSKSYGS-LEVFTDVD 350 +L+F P G P ++ G +SKS G+ + V+++ D Sbjct: 108 -----TGQLQF-KPNKSGIKPSSSVGGAINIDMSKSEGAGVVVYSNND 149
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 31.1 bits (70), Expect = 0.013 Identities = 13/28 (46%), Positives = 15/28 (53%) Query: 509 PVSSDQQQQQQQQNQAGPAAAAGIAGAA 536 P + QQQ Q QQ QA A +A AA Sbjct: 337 PPQAQQQQGQGQQQQAQATAQEAVAAAA 364 Score = 30.3 bits (68), Expect = 0.020 Identities = 13/29 (44%), Positives = 13/29 (44%) Query: 514 QQQQQQQQNQAGPAAAAGIAGAAATAVTA 542 Q QQQQ Q Q A A AA AV Sbjct: 339 QAQQQQGQGQQQQAQATAQEAVAAAAVRL 367
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 157 bits (398), Expect = 2e-47 Identities = 76/336 (22%), Positives = 132/336 (39%), Gaps = 30/336 (8%) Query: 3 TLLVTGAAGFIGSNFVRYWRERHPADAVVALDALT-YAGC---RENLDDLAER-ITFVHG 57 LVTGAAGFIG + + E VV +D L Y + L+ LA+ F Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIRDRELIESTLREHTVDVIVNFAAESHNSLAIIRPGDFFSTNVTGTQTLLEAARTVGVA 117 D+ DRE + + + ++ P + +N+TG +LE R + Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 RFHQISTCEVYGDMDLNDPGAFTEDAPY-LPRTPYNAAKAGGDHAVRAYGYTYDLPVTIT 176 S+ VYG LN F+ D P + Y A K + Y + Y LP T Sbjct: 120 HLLYASSSSVYG---LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 177 NCSNNYGPYQFPEKVIPLFVTRALQGEQLPLYASTTNRREWLHVMDHCRAIDAVLDRGRV 236 YGP+ P+ + F L+G+ + +Y +R++ ++ D AI + D Sbjct: 177 RFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH 236 Query: 237 ------------------GETYHVGSGVEADIETIADTVLAELGLPASLKTIVPDRPSHD 278 Y++G+ ++ + LG+ A K ++P +P Sbjct: 237 ADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEA-KKNMLPLQPGDV 295 Query: 279 RRYLLDSTKLRTELGWSPLIDFSEGMRSTIAWYKEN 314 D+ L +G++P +G+++ + WY++ Sbjct: 296 LETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 5e-19 Identities = 34/118 (28%), Positives = 56/118 (47%), Gaps = 2/118 (1%) Query: 10 RVLIAEDEALIRLDLREMLQEEGYEVVGEAGDGEMAVNLAGKLRPDLCILDVKMPRMDGI 69 +L+A+D+A IR L + L GY+V + DL + DV MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 70 EAGAKIAKDRI-APVVILTAFSQRELVERAREAGAMAYVVKPFQKKDLLPTIEMAMSR 126 + +I K R PV++++A + +A E GA Y+ KPF +L+ I A++ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 108 bits (271), Expect = 1e-30 Identities = 71/261 (27%), Positives = 116/261 (44%), Gaps = 35/261 (13%) Query: 1 MTGAGRGIGLAIVQALVREGYAVVAASRTITGALKELA--------PDALEMDLGTPEAP 52 +TGA +GIG A+ + L +G + A K ++ +A D+ A Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAI 72 Query: 53 EQLVRHALDRHGRIDLLVNNVAGTSTPPGGFLQLDDDAWQHTFTMTLMPTVRTTRAALPS 112 +++ G ID+LVN VAG PG L D+ W+ TF++ +R+ Sbjct: 73 DEITARIEREMGPIDILVN-VAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 113 LLEHR-GAVVNISSVNARLPQPRLVAQSALKAAVSNLGKALAEEFGGRGLRVNTISPGPV 171 +++ R G++V + S A +P+ + A ++ KAA K L E +R N +SPG Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 172 LTD----LWTAPGGP-----GDMFARRAGVPLEDYIDQIPSSIGVSTGQFTRPEEIADLV 222 TD LW G G + + G+PL + +P +IAD V Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKTGIPL---------------KKLAKPSDIADAV 235 Query: 223 VFLASGRVANMSGTELVIDGG 243 +FL SG+ +++ L +DGG Sbjct: 236 LFLVSGQAGHITMHNLCVDGG 256
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 56.9 bits (137), Expect = 2e-13 Identities = 26/60 (43%), Positives = 38/60 (63%) Query: 17 LREMIAKLIGSPPEDVPPDVNLILLGLTSIEIMRMVGRWRRAGFPVAFEELASAPTLSDW 76 +R+ IA+L+ PED+ +L+ GL S+ IM +V +WRR G V F ELA PT+ +W Sbjct: 235 IRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEW 294
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 61/309 (19%), Positives = 95/309 (30%), Gaps = 42/309 (13%) Query: 28 LWTASTLSAVGDGMSLTAAPLL--AYTLTDDPRLVAGVTTAL-TLPYVLFGLPAGVLVDR 84 + + L AVG G+ + P L ++D G+ AL L G L DR Sbjct: 10 ILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDR 69 Query: 85 VDLLRAMRGIDLFRGLLLLTLAVAVALDRGNLLVLYICFFLIGTCETFFRNASQVIVPSV 144 R L L + A+ L VLYI + G A I + Sbjct: 70 FG-----RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DI 123 Query: 145 VPRKLLVDANGRLLAAQTAGNEFVGPLLGSVLFAIAAAVPFGIDAASFLLSALLLSSLLG 204 G + A G GP+LG ++ + PF AA L+ L Sbjct: 124 TDGDERARHFGFMSACFGFGM-VAGPVLGGLMGGFSPHAPFFAAAALNGLNFLT--GCFL 180 Query: 205 VRSAKPSTRRTGGPSTSERPADLPAAPGSGVDSAGPVSATRPGLLADMTTGARWLLRDRL 264 + + RR P+ L RW + Sbjct: 181 LPESHKGERR-------------------------PLRREALNPL----ASFRWARGMTV 211 Query: 265 LRGLALAAGGINLVLTAGLAVMVVHAHTVLGLGSIGYGLLLAC-QAVGAVFAARLAPRLV 323 + L + LV A+ V+ + G+ LA + ++ A + + Sbjct: 212 VAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 324 RRLGDEQAL 332 RLG+ +AL Sbjct: 272 ARLGERRAL 280
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.1 bits (236), Expect = 1e-25 Identities = 58/184 (31%), Positives = 91/184 (49%), Gaps = 10/184 (5%) Query: 9 AVVTGASSGIGAATVRRLSKDGFSVVAVARRGERLRQVAEETGAQARVA-----DITDAA 63 A +TGA+ GIG A R L+ G + AV E+L +V A+AR A D+ D+A Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 64 AV----QQLAAELDSCDVLVNNAGGAIGADSVATGSPQDWERMFSVNVLGTLQITQALLP 119 A+ ++ E+ D+LVN G + + + S ++WE FSVN G ++++ Sbjct: 71 AIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 120 LLRSGRGGTIVTVTSTAAFTNYEGGGGYSAAKHAEHALSETLRLELCGESVRVIEVVPGM 179 + R G+IVTV S A Y+++K A ++ L LEL ++R V PG Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 180 VRTE 183 T+ Sbjct: 190 TETD 193
>PERTACTIN#Pertactin signature. Length = 922 Score = 26.6 bits (58), Expect = 0.038 Identities = 13/31 (41%), Positives = 20/31 (64%) Query: 53 LRVEIDSNITTVRVFVGDELVDIGTLTPIEP 83 +RVE +N+T R + D + IGTL P++P Sbjct: 163 VRVERGANVTVQRSTIVDGGLHIGTLQPLQP 193
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 119 bits (301), Expect = 3e-31 Identities = 95/426 (22%), Positives = 165/426 (38%), Gaps = 38/426 (8%) Query: 39 VLMATINSSILIIALPDIFRGIKVDPLAPGNTSYFLWTLMGFMLVTSVLVVSLGRVGDMF 98 + +N +L ++LPDI P + W FML S+ G++ D Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPP------ASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 99 GRVRMYNLGFAVFTVFSILLAVTWMHGTTAALWIIIMRVGQGIGGAFLFANSSAIIADAF 158 G R+ G + S++ V G + +I+ R QG G A A ++A Sbjct: 77 GIKRLLLFGIIINCFGSVIGFV----GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYI 132 Query: 159 PENERGLALGINGVAAIAGSFLGLLVGGLLAPVEWHLVFLVSVPFGIFGTVWAYLKLRDN 218 P+ RG A G+ G G +G +GG++A H +L+ +P TV +KL Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAH-YIHWSYLLLIPMITIITVPFLMKLLKK 191 Query: 219 GVRTRARIDWAGNITFAIGLIAILTGIIYGLQPYGGHTMGWTKPFVLICMFGGLAVLIGF 278 VR + D G I ++G++ + + + V + F F Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFM---------LFTTSYSISFLIVSVLSFL------IF 236 Query: 279 VVIELRSPDPMFKLELFSNRAFTMGSLAALLAALARGGLQFMIIIWLQGIWLPLHGYSFE 338 V + DP L N F +G L + G M+ ++ + H S Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV----HQLS-- 290 Query: 339 RTPLWAGIYMIPLTVGFLLSGPVAGRLADRYGARPFATIGLVTTAVAFLLFNVIPIDFN- 397 T + + P T+ ++ G + G L DR G IG+ +V+FL + + + Sbjct: 291 -TAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLL-ETTS 348 Query: 398 -YVAFAAILLLMGLSMGLFAAPNTTAVMNTLPPNQRGAGAGMLNTFQNSASVLSIGVFFT 456 ++ + +L GLS +T V ++L + GAG +LN + I + Sbjct: 349 WFMTIIIVFVLGGLSFTKTVI--STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 457 VIVLGL 462 ++ + L Sbjct: 407 LLSIPL 412
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 1e-10 Identities = 25/140 (17%), Positives = 45/140 (32%), Gaps = 7/140 (5%) Query: 23 RSRAETTEANTGRILRAATELFVERPFEHVTLPAVAERAGVGLQTVIRRVGTKDGLVRAV 82 R + + IL A LF ++ +L +A+ AGV + K L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 83 NRWIVPQIAATRGDPNDARPVGDDLAGVSDRL------ARHYEQWGRITERTLHQQDASP 136 I + P GD L+ + + L E+ + E H+ + Sbjct: 63 WELSESNIGELELEYQAKFP-GDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 137 ALKESADAGRRAHREWIEAV 156 + A R E + + Sbjct: 122 EMAVVQQAQRNLCLESYDRI 141
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 70.1 bits (171), Expect = 2e-14 Identities = 38/261 (14%), Positives = 83/261 (31%), Gaps = 14/261 (5%) Query: 332 ASQDRQDQPAPTAPPAPQAQQDQPAPTAPPAPQDQPALTASQAHQDQPALTAPPAPQAPK 391 + Q Q D P+ P + + P A P+ Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPS-----VPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 392 AQQDQPALTASQDRQDQPAPTAPPAPQAQQDQPAPTAPPAPQA-QPALTASQAHQDQPAL 450 ++ + + ++ +Q A + + Q + A + S+ + Q Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 451 TAPPAQQAP--KAQQDRQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQQDRQ 508 T A KA+ + + Q+ P +T+ +P+ ++ QP A PA + + + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ--AEPARE-NDPTVNIK 1156 Query: 509 DQQALTASQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQQ--DRQDQQALTA 566 + Q+ T + +QPA + P + T + P+ Q + Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVT-ESTTVNTGNSVVENPENTTPATTQPTVNSES 1215 Query: 567 SQDRQDQPALTAPPAPQAPKA 587 S +++ + P + Sbjct: 1216 SNKPKNRHRRSVRSVPHNVEP 1236 Score = 64.7 bits (157), Expect = 7e-13 Identities = 49/287 (17%), Positives = 96/287 (33%), Gaps = 35/287 (12%) Query: 230 DPQAPKVRQDQPAPTAPP---AQQDQPALTASQAHQDQPALTAPPAPQAPKAPKARQ--- 283 +P+ K Q Q D P++ ++ + AP P AP P Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVD-EAPVPPPAPATPSETTETV 1040 Query: 284 -DRQDQQALTASQDRQDQPAPTAPPAPQAQQDQPAPTAPPAQQDQPALTASQDRQDQPAP 342 + Q++ T ++ QD TA A++ + A Q ++ A + S+ ++ Q Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT-QTNEVAQSGSETKETQTTE 1099 Query: 343 TAPPAPQAQQDQPAPTAPPAPQDQPALTASQAHQDQPALTAPPAPQAPKAQQDQPALTAS 402 T A ++++ T Q+ P +T+ +P+ +++ QP A Sbjct: 1100 TKETATVEKEEK-----------AKVETEKT--QEVPKVTSQVSPKQEQSETVQPQ--AE 1144 Query: 403 QDRQDQPA-----PTAPPAPQAQQDQPAPTAPPAPQAQPALTASQAHQDQPALTAPPAQQ 457 R++ P P + A +QPA + +T S ++ P Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV--EQPVTESTTVNTGNSVVENPENT 1202 Query: 458 APKAQQDRQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQ 504 P Q + P + ++ + P P + Sbjct: 1203 TPATTQP----TVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Score = 63.9 bits (155), Expect = 1e-12 Identities = 45/322 (13%), Positives = 86/322 (26%), Gaps = 19/322 (5%) Query: 150 PMAPMAHQGRQDPQALAAQQDQQDQQDLAARLDRQDRPALTASQAPQDPQAPKVRQDQPA 209 P +Q Q D + + + R A P P P + A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVD-EAPVPPPAPATPSETTETVA 1041 Query: 210 PTAPPAQQDQPALTASQAPQDPQAPKVRQDQPAPTAPPAQQDQPALTASQAHQDQPALTA 269 + Q+ + Q + A + A + A + S + T Sbjct: 1042 ENSK--QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE------TK 1093 Query: 270 PPAPQAPKAPKARQDRQDQQALTASQDRQDQPAPTAPPAPQAQQDQPAPTAPPAQQDQPA 329 K + + + T + P Q Q + P A PA+++ P Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPK-QEQSETVQPQAEPARENDPT 1152 Query: 330 LTASQDRQDQPAPTAPPAPQAQQDQPAPTAPPAPQDQPALTASQAHQDQPALTAPPAPQA 389 + + P + A +QPA + +T S ++ P Sbjct: 1153 VNIKE-------PQSQTNTTADTEQPAKETSSNV--EQPVTESTTVNTGNSVVENPENTT 1203 Query: 390 PKAQQDQPALTASQDRQDQPAPTAPPAPQAQQDQPAPTAPPAPQAQPALTASQAHQDQPA 449 P Q +S +++ + P + + + A LT++ + Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSD 1263 Query: 450 LTAPPAQQAPKAQQDRQDRQDQ 471 A A + Q Sbjct: 1264 ARAKAQFVALNVGKAVSQHISQ 1285 Score = 60.1 bits (145), Expect = 2e-11 Identities = 44/285 (15%), Positives = 90/285 (31%), Gaps = 15/285 (5%) Query: 40 KGRQDHKALTASRARQVRQVRQALTAPQDQQAQQDRQDRQDPLAPTAHQGQRDQQAPTEP 99 GR D + Q T Q + +A AP P Sbjct: 975 NGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPP-APATP 1033 Query: 100 TEPTEPTAHQGQQDRQDQQAPTVR-TEPTAHQGRQDQQDQQALTEPMAPTAPMAPMAHQG 158 +E TE A +Q+ + + TE TA ++ + + + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNV--KANTQTNEVAQSGSE 1091 Query: 159 RQDPQALAAQQDQQDQQDLAARLD---RQDRPALTASQAPQDPQAPKVRQDQPAPTAPPA 215 ++ Q ++ +++ A+++ Q+ P +T+ +P+ Q+ V+ P A PA Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQ-----PQAEPA 1146 Query: 216 QQDQPALTASQAPQDPQAPKVRQDQPAPTAPPAQQDQPALTASQAHQDQPALTAPPAPQA 275 +++ P + + PQ +QPA + +T S ++ P Sbjct: 1147 RENDPTVNIKE-PQSQTNTTADTEQPAKETSSNV--EQPVTESTTVNTGNSVVENPENTT 1203 Query: 276 PKAPKARQDRQDQQALTASQDRQDQPAPTAPPAPQAQQDQPAPTA 320 P + + + R + P + + A Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 58.5 bits (141), Expect = 6e-11 Identities = 34/211 (16%), Positives = 71/211 (33%), Gaps = 18/211 (8%) Query: 381 LTAPPAPQAPKAQQDQPALTASQDRQDQP--APTAPPAPQAQQDQPAPTAPPAPQAQPAL 438 + Q D P++ ++ + + AP PPAP + A + Q Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK-- 1049 Query: 439 TASQAHQDQPALTAPPAQQAPKAQQDRQDRQDQPALTAPPAPQAPKARQDQPALTAPPAP 498 T + QD AQ ++ + + A A+ Sbjct: 1050 TVEKNEQDA---------TETTAQNREVAKEAKSNVKANTQ-TNEVAQSGSETKETQTTE 1099 Query: 499 QAPKAQQDRQDQQALTASQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQQDR 558 A +++++ + + Q+ P +T+ +P+ ++ QP A PA + + Sbjct: 1100 TKETATVEKEEKAKVETEK-TQEVPKVTSQVSPKQEQSETVQPQ--AEPARE-NDPTVNI 1155 Query: 559 QDQQALTASQDRQDQPALTAPPAPQAPKARQ 589 ++ Q+ T + +QPA + P Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTES 1186 Score = 57.8 bits (139), Expect = 1e-10 Identities = 41/290 (14%), Positives = 84/290 (28%), Gaps = 37/290 (12%) Query: 276 PKAPKARQDRQDQQALTASQDRQDQPAPTAPPAPQAQQDQ-----PAPTAPPAQQDQPAL 330 P+ K Q T + + D P+ + A+ D+ PAP P + A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 331 TASQDRQ----DQPAPTAPPAPQAQQDQPAPTAPPAPQDQPALTASQAHQDQPALTAPPA 386 + Q+ + ++ T A + + A + A + S + + T Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 387 PQAPKAQQDQPALTASQDRQDQPAPTAPP-APQAQQDQPAPTAPPAPQAQPALTASQAHQ 445 + ++ T + P Q++ QP A PA + P + + Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ--AEPARENDPTVNIKE--- 1157 Query: 446 DQPALTAPPAQQAPKAQQDRQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQQ 505 P++Q + +QPA + P + T + P+ Sbjct: 1158 -------------PQSQTNTTADTEQPAKETSSNVEQPVT-ESTTVNTGNSVVENPE--- 1200 Query: 506 DRQDQQALTASQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQ 555 A+ + P + ++ + P P + Sbjct: 1201 -----NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Score = 30.8 bits (69), Expect = 0.020 Identities = 24/100 (24%), Positives = 40/100 (40%), Gaps = 8/100 (8%) Query: 498 PQAPKAQQDRQDQQALTASQDRQDQPALTAPPAPQAPKARQDQPALTAPPAPQAPKAQQ- 556 P+ K Q T + + D P++ P+ AR D+ A PPAP P Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSV---PSNNEEIARVDE-APVPPPAPATPSETTE 1038 Query: 557 ---DRQDQQALTASQDRQDQPALTAPPAPQAPKARQDQQD 593 + Q++ T ++ QD TA A +A+ + + Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKA 1078
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.8 bits (69), Expect = 0.006 Identities = 15/57 (26%), Positives = 29/57 (50%), Gaps = 9/57 (15%) Query: 58 VLGLVRASGGRILIDGEDVSRYSPRQWRALRRRGVVQYVFQDPLRSLDPDLPIEESL 114 VL ++ + RI+ +G+D++ L R + DPL + PD+ ++E+L Sbjct: 509 VLPQIQETTARIIFNGKDLN---------LVERRIAAVNPSDPLETTKPDMTLKEAL 556
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 30.0 bits (67), Expect = 0.012 Identities = 34/134 (25%), Positives = 57/134 (42%), Gaps = 9/134 (6%) Query: 58 ILPA-HFAVSAGSI---EIAGRDIAGLTTPQWTDLRGSTISAVFQDPASYLNPSIKVGSQ 113 + PA H + +I E G+ I +T + + +S V D + I+ G Sbjct: 169 LTPASHMKIGNKNIFVKEYNGKGICCASTRESDHIANMWLSKVVDDEGKEIFSGIRHGVI 228 Query: 114 IAEVIQVKSGLRRRAARRRALELLTAVHLRDPELVYDQYTFELSGGMLQRVLIATAIAAD 173 A ++ S R AAR +A EL++A PEL+ LSG + +++T++ Sbjct: 229 SAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQA----LSGKTVDLKIVSTSLLT- 283 Query: 174 PQVLIADEATTALD 187 P L E + D Sbjct: 284 PTSLTGGEESMLKD 297
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.013 Identities = 19/55 (34%), Positives = 23/55 (41%), Gaps = 2/55 (3%) Query: 41 TAQAALAAVAGLAAAAGVAGPGSPAAAVAGLAAAAASAEPRSPARARSVPRPRHA 95 TA+A LA V+ AAAG AG G P +A A +P P P Sbjct: 379 TARALLADVSSPTAAAGGAGGGEPPKKRD--PSAGAGTDPGGPGGGDDGEDPFGE 431
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 53.3 bits (128), Expect = 4e-09 Identities = 32/153 (20%), Positives = 60/153 (39%), Gaps = 15/153 (9%) Query: 266 AAPLVFLVLLYAFGTVAAALLPVLVGVVSVVSSLALLRLAATLTDVSVFSVNLTT----A 321 A LVFLV+ + A L+P + V ++ + A+L +S+N T Sbjct: 347 AIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFG-------YSINTLTMFGMV 399 Query: 322 LGFGLAVDYSLFILRRF-REEQDRGLFPGAALRRTLETAGRTVFFSGVTVALSLTAALVF 380 L GL VD ++ ++ R + L P A +++ + + ++ F Sbjct: 400 LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFF 459 Query: 381 PLY---YLRSFAFAGIIVVVTSEVAALLVLPAA 410 R F+ + + S + AL++ PA Sbjct: 460 GGSTGAIYRQFSITIVSAMALSVLVALILTPAL 492 Score = 38.7 bits (90), Expect = 1e-04 Identities = 40/203 (19%), Positives = 67/203 (33%), Gaps = 47/203 (23%) Query: 602 VSSEAKDLVRELKAT-PAPFGVLMGGLAPHFLDTSRTILHRLPIAFAVVMAATFLLLFLF 660 S +A L+ L + PA G G++ + + P A+ FL L Sbjct: 835 SSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGN----QAPALVAISFVVVFLCLAAL 890 Query: 661 TGSVLLPLKAMFL----------------NSLNLAATIGLLA--------------FVFQ 690 S +P+ M + ++ +GLL F Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 691 EGHLRGL-VGDFQVSGTLEMTSPVLMFFIAFGLSMDYEIFLLARIREEYQRTGDNKESV- 748 G V + + P+LM +AF L + LA G + Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGV----LPLAIS------NGAGSGAQN 1000 Query: 749 AIGLGVTGPLITSVALALVVVMV 771 A+G+GV G ++++ LA+ V V Sbjct: 1001 AVGIGVMGGMVSATLLAIFFVPV 1023
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.2 bits (86), Expect = 1e-04 Identities = 19/99 (19%), Positives = 36/99 (36%), Gaps = 20/99 (20%) Query: 92 ASAVLGALVGDQIVGLVE-------YSTIGDEGDARFGILVESPHQGRGLGTLLIDILID 144 A + + +G ++ Y+ I D I V ++ +G+GT L+ I+ Sbjct: 64 GKAAFLYYLENNCIGRIKIRSNWNGYALIED-------IAVAKDYRKKGVGTALLHKAIE 116 Query: 145 TAGE---AGVRRLVADVPASSRRVLEVLRSVGFDLTPMD 180 A E G+ D+ S+ F + +D Sbjct: 117 WAKENHFCGLMLETQDINISA---CHFYAKHHFIIGAVD 152
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 202 bits (516), Expect = 2e-64 Identities = 83/304 (27%), Positives = 125/304 (41%), Gaps = 34/304 (11%) Query: 104 ADKVVHADITQRRPDWGLDRVDQRERPLDHKYVYD-STGARVTAYIVDTGIRTSHKDFGG 162 +V+ + G++ + V++ + G V ++DTG H D Sbjct: 9 PYQVIKQEQQVNEIPRGVEMIQ-------APAVWNQTRGRGVKVAVLDTGCDADHPDLKA 61 Query: 163 RASSGFSSIDDGHG----TDDCNGHGTHVAGTVGGS-----TYGIAKSVRLVAVRVLDCD 213 R G + DD G D NGHGTHVAGT+ + G+A L+ ++VL+ Sbjct: 62 RIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQ 121 Query: 214 GFGTVSGVIAGIDWITAHHASPAVVNVSL-EGDASRALDSAVRQSINAGLTYSVSAGNGG 272 G G +I GI + ++++SL + L AV++++ + + +AGN G Sbjct: 122 GSGQYDWIIQGIYYAIEQKVD--IISMSLGGPEDVPELHEAVKKAVASQILVMCAAGNEG 179 Query: 273 SDA----CDFSPARLPRAITVGATTTEDSRDTSYSNFGTCVDLFAPGTDVTSDWSASDTA 328 P I+VGA + + +SN VDL APG D+ S Sbjct: 180 DGDDRTDELGYPGCYNEVISVGAINFDRHA-SEFSNSNNEVDLVAPGEDILSTV--PGGK 236 Query: 329 TNTISGTSMAAPHVTGAAALYLE-----THPDAGPDRVRTALVTAAVPGVLTNVGNGSPN 383 T SGTSMA PHV GA AL + D + L+ +P L N N Sbjct: 237 YATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIP--LGNSPKMEGN 294 Query: 384 ALLY 387 LLY Sbjct: 295 GLLY 298
>PF07824#Type III secretion chaperone Length = 120 Score = 27.6 bits (61), Expect = 0.016 Identities = 14/51 (27%), Positives = 21/51 (41%), Gaps = 4/51 (7%) Query: 136 TDATTGAEVARYDLTEDASTETAMIFGELYRYGGEWKFRAVGQGYASGLRG 186 TD G+ +AR DLT E + E Y W + +A ++G Sbjct: 73 TDDEGGSLIARLDLTGINEFEDIYVNTEYYISRVRW----LKDEFARRMKG 119
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 6e-04 Identities = 24/187 (12%), Positives = 40/187 (21%), Gaps = 17/187 (9%) Query: 821 YDTAAAAAEREAIRARQDERVTLAAALSDRIAVDRDLAAALTGWRRSHPAGHLDRLEAQL 880 A R I +R E L ++++ S + Q Sbjct: 143 LLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK 202 Query: 881 TAARDTLAAAESELAAAGREAAAAEQAARRA---LADVEPL---------RVAAAEAAAR 928 L +E E +R L D L V E Sbjct: 203 YQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQE-NKY 261 Query: 929 ATALDQLARSVGDPAATEREIEQVAGVAEDRLAEARAAREHAASQRRAAAEAVRRADEAR 988 A+++L E EI A++ ++ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILS----AKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLE 317 Query: 989 RNAAAAR 995 R Sbjct: 318 LAKNEER 324
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 26.9 bits (59), Expect = 0.036 Identities = 11/23 (47%), Positives = 12/23 (52%) Query: 61 PDPSDAPGQPDTPAQPDTPGPPE 83 PD D P PD P PD P P+ Sbjct: 292 PDNPDNPNNPDNPNNPDEPNNPD 314
>PF01206#SirA family protein Length = 76 Score = 54.8 bits (132), Expect = 4e-14 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 1 MDSRGRRCPLPIIDLARAFASLVPGATIALWADDPAAGPDVAAWCRLRGQELVTVRALPG 60 +D+ G CPLPI+ + A++ G + + A DP + D ++ + G EL+ + Sbjct: 8 LDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE-ED 66 Query: 61 GGEEFVIRR 69 G F ++R Sbjct: 67 GTYHFRLKR 75
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 6e-08 Identities = 25/179 (13%), Positives = 57/179 (31%), Gaps = 11/179 (6%) Query: 17 PRPALAPPSPRLGEIIAVAREVLEKEGAAALTMRRLGELLGIRAPSLYKHLAGKNQLEAR 76 R I+ VA + ++G ++ ++ + + G+ ++Y H K+ L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 77 LVDAALVEIGDLLHGVVDR--ADAASVLGDLLAAYRAHARAHPNLYRLVTSGPLRRDQLT 134 + + + IG+L + D SVL ++L + RL+ + + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHV-LESTVTEERRRLLMEIIFHKCEF- 119 Query: 135 AGVEDWAGEPFYRATGEPYLAQALWAAAHGTVILELD-GRYLPGSDLDRTWAALTAAFG 192 GE + L + T+ ++ R + Sbjct: 120 ------VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 28.9 bits (64), Expect = 0.019 Identities = 23/95 (24%), Positives = 35/95 (36%), Gaps = 5/95 (5%) Query: 59 SPSGAGSPADVPSADVPSADVPSADGPSDAGPADGDPSDGDPSAGGSA-----GVAGGSD 113 +P A +P P +V A+ P+ + + P + DP A G G Sbjct: 316 TPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRP 375 Query: 114 DTPAAAARTVQAYFREINDATRAGRLAVITPTALA 148 D+PA R + +E + G L P LA Sbjct: 376 DSPAVPDRPNGRHRKERKEGEDGGLLCKFFPDILA 410
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 34.7 bits (79), Expect = 5e-04 Identities = 21/72 (29%), Positives = 27/72 (37%), Gaps = 18/72 (25%) Query: 180 VPESYTFNVDEPVVATISAIPHYRWEFGDGGTGPDAPGRPYDSAISPRDHPEAYVSHEYA 239 V E F+ E I Y W+FGDG S H+Y Sbjct: 787 VEEEINFDGTESKDED-GEIKAYEWDFGDGEK-------------SNEAKAT----HKYN 828 Query: 240 RPGQYQVTLTVT 251 + G+Y+V LTVT Sbjct: 829 KTGEYEVKLTVT 840
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 28.2 bits (63), Expect = 0.041 Identities = 18/86 (20%), Positives = 33/86 (38%), Gaps = 11/86 (12%) Query: 66 AIHDRRDQVQLA------TKFGIDRS----AGDGARVVRGERAYVQRAC-DASLLRLGVD 114 + D +D ++L + +G+ + G RVV G + +L+ D Sbjct: 55 DMKDHKDAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITD 114 Query: 115 VIDLYYLHRPPQTAEIEETVGAMGEL 140 I+L LH P I+ M ++ Sbjct: 115 CIELAPLHNPANIEGIKACTQIMPDV 140
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 29.4 bits (66), Expect = 0.020 Identities = 11/48 (22%), Positives = 20/48 (41%), Gaps = 3/48 (6%) Query: 168 TGQNVVELGIPD--IDRTHPDLAAMVGRGNYWVLGNGQSLSAQRNGDG 213 G+ V + + D D HPDL A + G + + ++ +G Sbjct: 39 RGRGVK-VAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNG 85
>adhesinb#Adhesin B signature. Length = 310 Score = 26.7 bits (59), Expect = 0.040 Identities = 7/22 (31%), Positives = 10/22 (45%) Query: 55 RPKIDPHDYETKKGHVVRFLRA 76 DPH+YE V + +A Sbjct: 62 PVGQDPHEYEPLPEDVKKTSQA 83
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 31.2 bits (70), Expect = 0.009 Identities = 26/79 (32%), Positives = 30/79 (37%), Gaps = 4/79 (5%) Query: 26 PLFGPSGAEYGPAAVPGTP----FHPAAAPAGPELPPLPSSANPAAPWQVPGGSPAASGV 81 P G A +PGT F P+ A A P + PL SSAN P AS Sbjct: 138 PFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSANSKYPRMFINQHQQASFK 197 Query: 82 AYPPRPAAEETAPAHREEA 100 Y + E AP E A Sbjct: 198 IYAEKIIMTEVAPLFNECA 216
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.6 bits (74), Expect = 0.003 Identities = 11/76 (14%), Positives = 17/76 (22%) Query: 9 SSTAIPAPPAPASPRSASSLPASPASAPPASALPADALPAAVGGTSGAGPATVDGDVDVT 68 IP PP A P P + + A P T Sbjct: 79 EPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPT 138 Query: 69 FASIEDAIAEIAAGRP 84 ++ A ++ Sbjct: 139 SSTATAATSKPVTSVA 154
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.024 Identities = 16/64 (25%), Positives = 29/64 (45%), Gaps = 2/64 (3%) Query: 309 RSSSAPESLEPVLRVDGLGVQFGRGRGR--KQALEDASLVIRPGETVGVIGESGAGKSTL 366 R+ + P+ L D GR ++ + +++ T+ + GESG GK + Sbjct: 117 RALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176 Query: 367 ARAV 370 ARA+ Sbjct: 177 ARAL 180
>PF04183#IucA / IucC family Length = 580 Score = 24.5 bits (53), Expect = 0.023 Identities = 5/22 (22%), Positives = 9/22 (40%) Query: 11 WPMARKYAAHLGQGTLRPLGPG 32 +A + A +G + LG Sbjct: 227 QKIATDFIADFAEGRMVSLGEF 248
>INTIMIN#Intimin signature. Length = 939 Score = 41.6 bits (97), Expect = 2e-05 Identities = 40/274 (14%), Positives = 84/274 (30%), Gaps = 18/274 (6%) Query: 539 RTAYVVDNASNDVTPIDVATGTPRARIPVGNDAHGIVITPDGRTAYVANAASNTVTPIDV 598 ++ Y +D D + + G + + ++ + +N T D Sbjct: 477 KSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGG--SNVYKVTARAYDR 534 Query: 599 ---ASNTAGTPIPAGNNPQWVTITPDGKTVYVTDNANAGSATVTPIDVATNTAGKAIPVS 655 +SN I +N Q + G T + D +A + I + + Sbjct: 535 NGNSSNNVLLTITVLSNGQ--VVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQA 592 Query: 656 DRPVGIAITPDGRTLYVTNERDNV--VTPIDVATNTPGATISTGGVEPFAIAVTPDGVAA 713 + PV I L + N + + ++ PG + + A+ + V Sbjct: 593 NVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIF 652 Query: 714 YAVNRDSNSVTPIDVATNTAGAPISV--------GERPVGIA-IAPAPAVPAGPVCGKTG 764 + S + D T A ++ G++PV + + + Sbjct: 653 VDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKT 712 Query: 765 AQSGTTTMTCTYDTVGSDTFTVPAGVSSVEITAT 798 +G +T T T G + +V++ A Sbjct: 713 DTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAP 746
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 101 bits (253), Expect = 2e-25 Identities = 83/389 (21%), Positives = 146/389 (37%), Gaps = 16/389 (4%) Query: 4 DISRDLDTTVQAVQVVITVFLLVMAALMIPGGKLTDLLGRKRCFLIGLAVYGTGAVLSAA 63 DI+ D + + V T F+L + GKL+D LG KR L G+ + G+V+ Sbjct: 39 DIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFV 98 Query: 64 APGVGVLLVGNSILEGVGTALLIPPVYILTTLLFTDLTARAHAFGMIMAAGGLGAAAGPL 123 LL+ ++G G A V ++ R AFG+I + +G GP Sbjct: 99 GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK-ENRGKAFGLIGSIVAMGEGVGPA 157 Query: 124 IGGLITSAISWRAAFAFQALVIALIIALSRSVPDPLPPDPHRHFDIPGAVLSAGGLTLVV 183 IGG+I I W + I + L + + + HFDI G +L + G+ + Sbjct: 158 IGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIK--GHFDIKGIILMSVGIVFFM 215 Query: 184 MGILAADDSLARTAALLAAGMLVLAGFLHWVRVEERAGREPLLSTSLFRNRNANLGLVTQ 243 + T+ ++ ++ + FL +V+ + P + L +N +G++ Sbjct: 216 LFT---------TSYSISFLIVSVLSFLIFVKHIRKVTD-PFVDPGLGKNIPFMIGVLCG 265 Query: 244 NIQWLLLMGSSFTVATYLQVVRGYDAIRTGLIFT-AATVGLLASSLAAERFAKRRSQGTL 302 I + + G V ++ V G + T+ ++ RR + Sbjct: 266 GIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYV 325 Query: 303 ITAGFALAVAGIVLLIGLVAGSRSPWAFVPGLLLLGLGLGVMLTPSVNVVQSAFSEQRQG 362 + G + L+ + W ++ + GL T +V S+ +Q G Sbjct: 326 LNIGVTFLSVSFLTASFLLET--TSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAG 383 Query: 363 EISGLSRSISNLGSSFGTAIAGTILVAGL 391 L S L G AI G +L L Sbjct: 384 AGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 24.4 bits (53), Expect = 0.035 Identities = 8/18 (44%), Positives = 13/18 (72%) Query: 9 TDAADLLGVSRSTIYDLL 26 AADLLG++R+T+ + Sbjct: 453 IKAADLLGLNRNTLRKKI 470
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 38.9 bits (90), Expect = 5e-06 Identities = 15/69 (21%), Positives = 19/69 (27%), Gaps = 1/69 (1%) Query: 93 PTPTGTVTPTPTPAPTATEDPAATASPTAASTPLSPTATADTGSGLRSDGTAATPGATAP 152 + + TP P A A + +T L S G A P TA Sbjct: 461 GKASDSQTPDAKPGNKAV-PGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAA 519 Query: 153 APAATPGLG 161 A G Sbjct: 520 ALTVMATAG 528
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 45.9 bits (108), Expect = 7e-07 Identities = 63/246 (25%), Positives = 96/246 (39%), Gaps = 41/246 (16%) Query: 161 RAGIVHRDLKPSNILLSRLG--PKVIDFGIARALDTATRLDLDHGGDRQLG-TPAFMAPE 217 +AG+VH D+KP N++ R P VID G+ G++ G T +F APE Sbjct: 263 KAGVVHNDIKPGNVVFDRASGEPVVIDLGLH-----------SRSGEQPKGFTESFKAPE 311 Query: 218 QAKGE-QVTSAADVFAWGGVLIYA--GTGRYPFGGGPTPGLLFRTVNEP----------- 263 G + +DVF L++ G + P P GL F T +EP Sbjct: 312 LGVGNLGASEKSDVFLVVSTLLHCIEGFEKNP-EIKPNQGLRFIT-SEPAHVMDENGYPI 369 Query: 264 --PTLDGFEDSLRPLVEDAMRKVAADRPRAEELYARLLDLRADAPVPVPQPPLSLSE-VT 320 P + G E + + D + A RP + E ARL + +D + L + +T Sbjct: 370 HRPGIAGVETAYTRFITDILGVSADSRPDSNE--ARLHEFLSDGTIDEESAKQILKDTLT 427 Query: 321 ALIRPLNTTPRGTQPPPTPAAADPLTPVTPITDHQPVGPPPEFPPTPARADLSGSLPSAD 380 + PL+T R P +D L H + +DL L + D Sbjct: 428 GEMSPLSTDVRRITPKKLRELSDLL------RTHLSSAATKQLDMGGVLSDLDTMLVALD 481 Query: 381 RGDRSG 386 + +R G Sbjct: 482 KAEREG 487
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 44.3 bits (104), Expect = 5e-07 Identities = 17/68 (25%), Positives = 28/68 (41%) Query: 277 ELPAGAPPVESAPAARPPDTPEPDTAPAPDAEPVPDAAPESATEPEPDTEPEPDESAESD 336 +L A + A + D+ PD P A P AP++ T+P + P + + Sbjct: 447 KLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLP 506 Query: 337 ETAESCVP 344 T E+ P Sbjct: 507 STGETANP 514
>cloacin#Cloacin signature. Length = 551 Score = 29.3 bits (65), Expect = 0.035 Identities = 13/25 (52%), Positives = 14/25 (56%) Query: 6 GGSADGPAAGPGRGGGPGGGGGPAG 30 GGS G G G G G GGG G +G Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSG 72
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 98.6 bits (245), Expect = 1e-26 Identities = 57/256 (22%), Positives = 108/256 (42%), Gaps = 12/256 (4%) Query: 18 VAGRTVVVTGGSKGIGKGIARVFATAGANVVLSGRDVVAAATTAQELDELGEGTVSFVLA 77 + G+ +TG ++GIG+ +AR A+ GA++ + L +F Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA- 64 Query: 78 DAASAEDSARLARTVAERHGGVDVVCANAGIFPSVPLATITEADIDEVLGTNVKGAILTV 137 D + + + G +D++ AG+ + ++++ + + N G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 138 QAFLPALVASGRGRVILTSSITGPVTGHPGWSHYGASKAAVLGFMRTAAVELARDRVTVN 197 ++ ++ G ++ S + Y +SKAA + F + +ELA + N Sbjct: 125 RSVSKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 198 AVLPGSVRTE----------GLDELGADYLNSMEAAIPMRRLGEVDEIGHAALFLASDEA 247 V PGS T+ G +++ L + + IP+++L + +I A LFL S +A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 248 SYITGQALVVDGGQIL 263 +IT L VDGG L Sbjct: 244 GHITMHNLCVDGGATL 259
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.9 bits (77), Expect = 8e-04 Identities = 14/57 (24%), Positives = 19/57 (33%), Gaps = 2/57 (3%) Query: 138 APEIVQ--AVTAPAPSTPPTPSSPPTPSIPPTPSTPPTAPNPPTAPASPSARDLPAS 192 A E+ + A A TP T PN AP + R LP++ Sbjct: 452 AEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPST 508
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 178 bits (452), Expect = 2e-55 Identities = 86/334 (25%), Positives = 133/334 (39%), Gaps = 37/334 (11%) Query: 32 RAIVTGGAGFLGSHLCERLLGDGYEVICFDNFLTGRPDNVEH----LLVDPRFRLVNRDV 87 + +VTG AGF+G H+ +RLL G++V+ DN +++ LL P F+ D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 88 NDF-----IYVSGPVDVVLHFASPASPLDYYELPIETLKVGSLGTFHALGLARE-KRARF 141 D ++ SG + V + E P G + L R K Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 142 LLASTSESYGDPQVNPQPETYWGNVNPVG-PRSVYDEAKRFAEAVTMAYRRKHGVDTAIV 200 L AS+S YG + P + V P S+Y K+ E + Y +G+ + Sbjct: 122 LYASSSSVYGLNRKMPFST-----DDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGL 176 Query: 201 RIFNTYGPRMRVDDGRAIPAFVSQALRGEPITVAGDGSQTRSICYVDDLIDGILRLLH-- 258 R F YGP R D A+ F L G+ I V G R Y+DD+ + I+RL Sbjct: 177 RFFTVYGPWGRPD--MALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 259 ----------------SDLPGPV-NIGNPHEMSILDTAKLVRDLCGSTAPITFVPRPQDD 301 S P V NIGN + ++D + + D G A +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 302 PSVRQPDITIARTRLGWEPRTSLHDGLTRTISWF 335 D +G+ P T++ DG+ ++W+ Sbjct: 295 VLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 37.3 bits (86), Expect = 2e-04 Identities = 28/100 (28%), Positives = 35/100 (35%), Gaps = 1/100 (1%) Query: 658 VPASPVPASPVPASPVPASPTAEPSSASPVPASPVPASPTAEPSSASPVSASPTAEPPAA 717 V P PA P+ + V + P + P P V P EP P A E P Sbjct: 40 VIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKP 99 Query: 718 HPVP-PSTAGPVPPPTRRPDEPDAGTAAPAVNAADVLPPP 756 P P P V P R ++ A+P N A P Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTS 139 Score = 36.5 bits (84), Expect = 3e-04 Identities = 19/99 (19%), Positives = 30/99 (30%) Query: 629 PVPPSPLPPSLLPPSSDSPAFHPPSSASPVPASPVPASPVPASPVPASPTAEPSSASPVP 688 P P P+ +++ P+ P PV P+P P A E P P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Query: 689 ASPVPASPTAEPSSASPVSASPTAEPPAAHPVPPSTAGP 727 PV + P + P P+++ Sbjct: 104 KPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTA 142 Score = 34.2 bits (78), Expect = 0.002 Identities = 28/123 (22%), Positives = 36/123 (29%), Gaps = 1/123 (0%) Query: 635 LPPSLLPPSSDSPAFHPPSSASPVPASPVPASPVPASPVPASPT-AEPSSASPVPASPVP 693 LP P+ S H A + S +PA P S T P+ P A P Sbjct: 10 LPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPP 69 Query: 694 ASPTAEPSSASPVSASPTAEPPAAHPVPPSTAGPVPPPTRRPDEPDAGTAAPAVNAADVL 753 P EP P E P P P P P ++ ++P A Sbjct: 70 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPF 129 Query: 754 PPP 756 Sbjct: 130 ENT 132 Score = 29.6 bits (66), Expect = 0.046 Identities = 21/112 (18%), Positives = 26/112 (23%), Gaps = 5/112 (4%) Query: 644 SDSPAFHPPSSASPVP----ASPVPASPVPASPVPASPTAEPSSASPVPASPV-PASPTA 698 + PA P S + V P P P V P EP P A V Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK 100 Query: 699 EPSSASPVSASPTAEPPAAHPVPPSTAGPVPPPTRRPDEPDAGTAAPAVNAA 750 PV + + RP A A + Sbjct: 101 PKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTS 152
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 91.0 bits (226), Expect = 5e-22 Identities = 95/383 (24%), Positives = 151/383 (39%), Gaps = 76/383 (19%) Query: 17 FGIDLGTTFSCLARVSNAG----EPLIVPLSDGALTLPSVVLFVGADDYLTGQTARELAR 72 IDLGT + L V G EP +V + P V VG D A+++ Sbjct: 13 LSIDLGTA-NTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHD-------AKQMLG 64 Query: 73 ARPDDVCSLVKRRMGDGDWRFITQGAAWSAPAVSGLILKALVADTALATGERVEDVVITV 132 P ++ ++ R M DG + + +K + +++ + RV ++ V Sbjct: 65 RTPGNIAAI--RPMKDG-----VIADFFVTEKMLQHFIKQVHSNSFMRPSPRV---LVCV 114 Query: 133 PAYFGDEERRATVLAGEYAGLNVVDVINEPTAAALSYGFARFEMGSRRTLGGPGATAEEV 192 P ERRA + + AG V +I EP AAA+ G E Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSE--------------ATG 160 Query: 193 ALVYDLGGGTFDVTVVELADRRVSVVAIDGDHQLGGADWDEKIVLHLCDRFLVEHPGAPD 252 ++V D+GGGT +V V+ L V ++GG +DE I+ ++ + Sbjct: 161 SMVVDIGGGTTEVAVISLNG-----VVYSSSVRIGGDRFDEAIINYVRRNYGSL------ 209 Query: 253 PLDAGESSQALLLAAERARRDLTDA--AATTVVVEHAGR-------RTGVVLTRDELERL 303 GE++ AER + ++ A +E GR R + + + LE L Sbjct: 210 ---IGEAT------AERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 304 TAGLLDRTVALTRAARDAA--LARGVRGIDR-ILLVGGASRMPAVGRRLAAEFGVPVELT 360 L A+ A LA + +R ++L GG + + + R L E G+PV + Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDI--SERGMVLTGGGALLRNLDRLLMEETGIPVVVA 318 Query: 361 -DPDLAVARGAAVYGEKKALERL 382 DP VARG KALE + Sbjct: 319 EDPLTCVARGGG-----KALEMI 336
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.6 bits (71), Expect = 0.005 Identities = 29/88 (32%), Positives = 40/88 (45%), Gaps = 3/88 (3%) Query: 30 PRRAVGRGGRSDTDLSPGVGDDAEVPRDAPTRTIDDVGLPAAPETAPPRADASGPPVIGD 89 P V G +D + +P V A RD+ T DV + P+ P A+A + + Sbjct: 272 PGTKVNMGPVTDRNGNP-VQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPE 330 Query: 90 VATA-GPAENLAPSVPPQQRPPAEMPAP 116 V+ A PA N AP+ P RP E P P Sbjct: 331 VSPAENPANNPAPNENPGTRPNPE-PDP 357
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 45.8 bits (108), Expect = 1e-06 Identities = 50/337 (14%), Positives = 107/337 (31%), Gaps = 27/337 (8%) Query: 142 RKRKEKALRKLEAMAANLTRLTDLSAELRRQLGPLGRQAEIARKAGVIQASLRDARLRLL 201 +++ K + L A+ + L A+L + L Sbjct: 98 KEKLRKNDKSLSEKASKIQELEARKADLEKALEGA------------------MNFSTAD 139 Query: 202 ADELNSARTAIASDVVDEEALRRRLTDSESAQHAAAQREAQLQSELAAVVPRAAAAQETW 261 + ++ + A+ + L + L + + A + + L++E AA+ R A ++ Sbjct: 140 SAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA- 198 Query: 262 YAMASLRERLLGTRSLATERARLLRIGSDELRGRRDPDELEQEAIAVREQEIALTERLER 321 + + + D ++ + A+ + A + LE Sbjct: 199 --LEGAMNFSTADSAKIKTLEAEKAALAARKA---DLEKALEGAMNFSTADSAKIKTLEA 253 Query: 322 DRELLEEVVVRRADLEAALADEERELIAAARAASSRREELARLAGQVEAARSRATGAEEE 381 ++ LE R+A+LE AL A + + E A L + ++ Sbjct: 254 EKAALEA---RQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNAN 310 Query: 382 IARTTEALTAARERDAEAAQSTTALQTELAQMEGAREELAERHDAAVAVHASATDRLEML 441 L A+RE + L+ + E +R+ L DA+ + L Sbjct: 311 RQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKL 370 Query: 442 RAEERAAERDRASWTARRDALQLSLAPADGVAALLEA 478 + + +E R S DA + + + + Sbjct: 371 EEQNKISEASRQSLRRDLDASREAKKQVEKALEEANS 407 Score = 33.9 bits (77), Expect = 0.005 Identities = 45/290 (15%), Positives = 98/290 (33%), Gaps = 2/290 (0%) Query: 133 EEAAGVLKHRKRKEKALRKLEAMAANLTRLTDLSAELRRQLGPLGRQAEIARKAGVIQAS 192 + K E L A A+L + + + + E + A + + Sbjct: 134 NFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 193 Query: 193 LRDARLRLLADELNSARTAIASDVVDEEALRRRLTDSESAQHAAAQREAQLQSELAAVVP 252 + L + + I + ++ AL R D E A A +++ + Sbjct: 194 ELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEA 253 Query: 253 RAAAAQETWYAMASLRERLLGTRSLATERARLLRIGSDELRGRRDPDELEQEAIAVREQE 312 AA + + E + A++ + +++ + +LE ++ + Sbjct: 254 EKAALEARQAELEKALEGA--MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR 311 Query: 313 IALTERLERDRELLEEVVVRRADLEAALADEERELIAAARAASSRREELARLAGQVEAAR 372 +L L+ RE +++ LE E + R + RE +L + + Sbjct: 312 QSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLE 371 Query: 373 SRATGAEEEIARTTEALTAARERDAEAAQSTTALQTELAQMEGAREELAE 422 + +E L A+RE + ++ ++LA +E +EL E Sbjct: 372 EQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEE 421 Score = 33.1 bits (75), Expect = 0.008 Identities = 43/223 (19%), Positives = 67/223 (30%), Gaps = 11/223 (4%) Query: 775 ALHGADARYRALSEQVAQLERAWGGAGSEVARLEAARGRAETARDRAYGALSELETALAA 834 AL GA A S ++ LE + A LE A A + LE AA Sbjct: 128 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 187 Query: 835 TSAQPEIDEPTPAERDRLVSATSAVRAAEVEARLAVRTSEERARGLQGRADGLIRAAASE 894 A+ E +A SA + A+ + A A +++ Sbjct: 188 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK 247 Query: 895 RAARVAAA-----------RRREVRERQAAVAAALGDATQVTLDRLDRSLARAATERAEA 943 A + E + +A + L+ A + Sbjct: 248 IKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVL 307 Query: 944 EALRRATETNLAAVREQARALAAEVAALRDAAHRDELARAEKR 986 A R++ +L A RE + L AE L + E +R R Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 350
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 205 bits (522), Expect = 8e-71 Identities = 80/157 (50%), Positives = 111/157 (70%), Gaps = 5/157 (3%) Query: 4 AVCPGSFDPITNGHLDIVIRASKLFDEVVVAVSINKNKATLFTIDERMELIREAVRNHPM 63 A+ PGSFDPIT GHLDI+ R +LFD+V VAV N NK +F++ ER+E I +A+ + P Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP- 61 Query: 64 APSNVVVDASHGLVVDFCRARGIQSIVKGLRAVSDFDYELQMAQMNNSLA-GVETLFMST 122 N VD+ GL V++ R R +I++GLR +SDF+ ELQMA N +LA +ET+F++T Sbjct: 62 ---NAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTT 118 Query: 123 NPQYAFLSSSLVKEVARYGGDVSHLVPDVVLKQLRER 159 + +Y+FLSSSLVKEVAR+GG+V H VP V L ++ Sbjct: 119 STEYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQ 155
>cloacin#Cloacin signature. Length = 551 Score = 27.8 bits (61), Expect = 0.033 Identities = 18/47 (38%), Positives = 22/47 (46%), Gaps = 6/47 (12%) Query: 137 GGGGGGGAGGGGHTAGDPGRVVDGEVVDRAEWVAAPEADGGPAGARP 183 GG G G GG G++ G G + VAAP A G PA + P Sbjct: 58 GGSGHGNGGGNGNSGGGSGTGGNLSA------VAAPVAFGFPALSTP 98
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.5 bits (113), Expect = 5e-10 Identities = 19/78 (24%), Positives = 41/78 (52%), Gaps = 4/78 (5%) Query: 2 VRTVDPQVITLDIMMPRMNGWDVAAALRE-DPSTADIKLIMLTARAQEADVKRGARIGVD 60 + D ++ D++MP N +D+ +++ P D+ +++++A+ + + G Sbjct: 43 IAAGDGDLVVTDVVMPDENAFDLLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAY 99 Query: 61 YYLTKPFDPDELITVVQK 78 YL KPFD ELI ++ + Sbjct: 100 DYLPKPFDLTELIGIIGR 117
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 42.5 bits (100), Expect = 1e-06 Identities = 26/183 (14%), Positives = 49/183 (26%), Gaps = 42/183 (22%) Query: 27 RLRRDVFV--------VEQGLFGGTARGGTDHDDADDDERTVVLLARAAGGELLGGVRLH 78 LR++ F G+ D D+ T L ++ +R Sbjct: 22 TLRKETFKDRLNWAVQCTDGM----------EFDQYDNNNTTYLFGIK-DNTVICSLRFI 70 Query: 79 CATGADL-----------------GWWRGGRLAVVRPARGGAGHGAGHGAGIGSALVRAA 121 ++ + R V + A G+ I S L + Sbjct: 71 ETKYPNMITGTFFPYFKEINIPEGNYLESSRFFV---DKSRAKDILGNEYPISSMLFLSM 127 Query: 122 CAFAEQAGVLRFEATVQAAGEPAFQRLGWRSVRPCTVAGKPH---VLMRWPIDRLARQAA 178 +++ G V +R GW + L+ P+D ++A Sbjct: 128 INYSKDKGYDGIYTIVSHPMLTILKRSGWGIRVVEQGLSEKEERVYLVFLPVDDENQEAL 187 Query: 179 ATK 181 A + Sbjct: 188 ARR 190
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 61.6 bits (149), Expect = 1e-14 Identities = 25/63 (39%), Positives = 39/63 (61%), Gaps = 2/63 (3%) Query: 1 MFNGVGWGEVVVLLLIGLFVFGPDRLPKAARDAGRMLRQLRQMANGMRNDLRSELG-PEF 59 MF+ +G+ E++++ +IGL V GP RLP A + +R LR +A ++N+L EL EF Sbjct: 1 MFD-IGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEF 59 Query: 60 ADL 62 D Sbjct: 60 QDS 62
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 60.8 bits (147), Expect = 1e-11 Identities = 36/200 (18%), Positives = 62/200 (31%), Gaps = 31/200 (15%) Query: 760 PVTDRRTVAAIAAAALPTVVTVDVGGVGDDGSGGTGSGVIISSDGFILTNNHVIASAVAS 819 P DR + V + V SGV++ D +LTN HV+ + Sbjct: 72 PNNDRHQITDTTNGHYAPVTYI---QVEAPTGTFIASGVVVGKD-TLLTNKHVVDATHGD 127 Query: 820 GSPISVRRYQEFGQ-------IQAQLVGRDPQTDLAVLRI-------PAPTPLPAATLGQ 865 + Q+ + DLA+++ + AT+ Sbjct: 128 PHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSN 187 Query: 866 SGSLVVGAPVVAIGAPLGLSGTVTTGVVSALDRNPTVPAENGSAPTVLIGAIQIDAAINP 925 + V + G P T+ G + A+Q D + Sbjct: 188 NAETQVNQNITVTGYPGDKP-------------VATMWESKGKITYLKGEAMQYDLSTTG 234 Query: 926 GNSGGPLLDALGQVVGINAA 945 GNSG P+ + +V+GI+ Sbjct: 235 GNSGSPVFNEKNEVIGIHWG 254
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 57.7 bits (139), Expect = 1e-11 Identities = 43/212 (20%), Positives = 68/212 (32%), Gaps = 26/212 (12%) Query: 32 TIVTQVAAALTPSVASLRVRTRRGAGAGSAVVFTDDGFLLTSAHVVEGLLGGGGAAVGLA 91 +T V ++V G S VV D LLT+ HVV+ G A Sbjct: 77 HQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKD-TLLTNKHVVDATHGDPHALKAFP 135 Query: 92 QFADGTEREF------DVVGADPLSDLAVL--------RARGATPRAAVLGDAAGLRVGQ 137 + + DLA++ + G + A + + A +V Q Sbjct: 136 SAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQ 195 Query: 138 LVVAVGNPLGLTGSVTAGVVSALGRSLPTRAGSAVRVVDEVIQTDAALNPGNSGGALGTA 197 + G P V+ + S G + E +Q D + GNSG + Sbjct: 196 NITVTGYPGDKP-------VATMWES----KGKITYLKGEAMQYDLSTTGGNSGSPVFNE 244 Query: 198 DARVVGINTAVAGVGLGLAIPVNAATRKILAA 229 V+GI+ A+ +N R L Sbjct: 245 KNEVIGIHWGGVPNEFNGAVFINENVRNFLKQ 276
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 172 bits (438), Expect = 2e-48 Identities = 95/437 (21%), Positives = 176/437 (40%), Gaps = 68/437 (15%) Query: 7 LRNVAIIAHVDHGKTTLVDAMLRQSGAFGE--HAELTDRVMDSMDLEREKGITILAKNTA 64 + N+ ++AHVD GKTTL +++L SGA E + D+ LER++GITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 65 VRHGDMTINIIDTPGHADFGGEVERGLSMVDGVLLLVDASEGPLPQTRFVLRKALAARLP 124 + + +NIIDTPGH DF EV R LS++DG +LL+ A +G QTR + +P Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 125 VVLVINKVDRSDARIAEVVDE-------------TYELFLDLDA----DEEQIDFPIIYC 167 + INK+D++ ++ V + EL+ ++ + EQ D I Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVI--- 179 Query: 168 NAKAGRASTTRPADGASPDSPDL---------------------------KPLFDLLLET 200 + + G S ++ +L L +++ Sbjct: 180 --EGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNK 237 Query: 201 VPAPSFDPDAPLQALVTNLDASPYLGRLALCRVHNGTIKRGQQATLCRADGTQTRVKISE 260 + + + L V ++ S RLA R+++G + + + ++KI+E Sbjct: 238 FYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKE----KIKITE 293 Query: 261 MLMTQALERVPAEEAGPGDIIAIAGIPDITIGETLAD-LDDPRPLPVITVDEPSISMTIG 319 M + E ++A G+I+ + + + L D P+ I P + T+ Sbjct: 294 MYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQR-ERIENPLPLLQTTVE 351 Query: 320 INTSPLAGRSGKKLTARLVKNRLDAELVGNVSIRVLPTERPDTWEVQGRGELQLAVLVEL 379 + L + + +R + G++Q+ V L Sbjct: 352 PSKPQQREMLLDALLE------ISDS---DPLLRYYVDSATHEIILSFLGKVQMEVTCAL 402 Query: 380 MRRE-EFELTVGKPQVV 395 ++ + E+ + +P V+ Sbjct: 403 LQEKYHVEIEIKEPTVI 419 Score = 37.9 bits (88), Expect = 1e-04 Identities = 17/83 (20%), Positives = 28/83 (33%), Gaps = 1/83 (1%) Query: 403 VHEPVERLTIDAPEEFLGTLTQLLALRKGRVEQMVNHGTGWIRLEYLVPARGLIGFRTEF 462 + EP I AP+E+L + + L +PAR + +R++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDL 593 Query: 463 LTETRGTGLLHHVFDRYEPWFGE 485 T G + Y GE Sbjct: 594 TFFTNGRSVCLTELKGYHVTTGE 616
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 143 bits (363), Expect = 1e-39 Identities = 83/409 (20%), Positives = 162/409 (39%), Gaps = 18/409 (4%) Query: 55 VLAVCCLAQFMVVLDISIVNVALPAMQTDLGMSASGLQWVVNAYTLAFAGLLLFGGRAAD 114 +L C+ F VL+ ++NV+LP + D + WV A+ L F+ G+ +D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 115 LFGRRRVFVFGLVLFTLASLAGGLAQSETQ-LIIARAVQGLGGAVLAPATLSLLMTSFAE 173 G +R+ +FG+++ S+ G + S LI+AR +QG G A PA + +++ + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIP 133 Query: 174 GRERTRALGAWGATAASGGAFGTVVGGILTDVADWRWVLFVNVPIGVALVVAARVVLVES 233 R +A G G+ A G G +GG++ W ++L + + I + V +L + Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKK- 191 Query: 234 RGQVSRVRDLDLPGTLTVTGGLVLLVYAIVRTETSSWSSPLTIGLLAAAVVLLGAFVAIE 293 +V D+ G + ++ G+V + T + S L +V+ FV Sbjct: 192 --EVRIKGHFDIKGIILMSVGIVFFMLF---TTSYSI------SFLIVSVLSFLIFVKHI 240 Query: 294 ATTANPLVPLNIFRYPGIAVANVVAALLGAAMFAVFFFLTLFLQRVENYSPLRAGLS-ML 352 +P V + + + + ++ + + ++ V S G + Sbjct: 241 RKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIF 300 Query: 353 PMPLMIIVASQLVTRTIGRLGARPIVMFGAAVGSSGLLWLSAITPGGSYWTHVFGPLAVM 412 P + +I+ + + R G ++ G S L + + W + V+ Sbjct: 301 PGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTA-SFLLETTSWFMTIIIVFVL 359 Query: 413 GFGMGTTMVSMVSAATAGVPIRLAGLASGLINTGRQIGAAVGLAAVTTI 461 G T V +++ AG L+N + G+A V + Sbjct: 360 GGLSFTKTVISTIVSSSLKQQE-AGAGMSLLNFTSFLSEGTGIAIVGGL 407
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 76.5 bits (188), Expect = 1e-18 Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 5/171 (2%) Query: 45 TSLSPERLALAAIALADAEGLAAVSMRRLAASLGVGTMTLYYHVRDKDELLDLMWNEFLG 104 L+ E + AA+ L + G+ ++ R+LA LG+ TLY+HV++K LLD + E L Sbjct: 2 ARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILA 61 Query: 105 GHLLDDIPA---DWRTALTEIARRIRQSFQRHPWALGVAVRPALGPNKLRYLEQYLTVAS 161 H +PA W++ L A R++ R+ V + + +E L + Sbjct: 62 RHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFMT 121 Query: 162 RITDDPDEQLRIIHSVSDLVVGCTLRELGGQAYRDPDEPAGEHADGPAPLL 212 + L I +VS +G L + A D PA + PLL Sbjct: 122 ENGFSLRDGLYAISAVSHFTLGAVLEQQEHTA-ALTDRPAAP-DENLPPLL 170
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.0 bits (80), Expect = 0.001 Identities = 28/201 (13%), Positives = 46/201 (22%), Gaps = 19/201 (9%) Query: 660 ADVPGAPSASAGRQPAQGAGQAPGSAPGPSVQLPEGLLVTPLTPTGRPAAQPPASRETAP 719 ADVP PS + +AP P P+ V + + T Sbjct: 1005 ADVPSVPSNNEEIARVD---EAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATET 1061 Query: 720 TGQPG-------ATTPGTAGTDRVPAVPVAAAAALPVAA--AALPAASGGAAPAAQPQAR 770 T Q + T+ V A A + Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 771 KP-----ARPQGQSQAQTRAQGQPQAQTQTQTQTQTPTQTQAQTQAQTPAQPQTQPPGQP 825 P P+ + + Q +P + + P T +T + Sbjct: 1122 VPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQ 1181 Query: 826 P--AAGTSSAAPRSGLTPVQV 844 P + T + P Sbjct: 1182 PVTESTTVNTGNSVVENPENT 1202
>PF04619#Dr-family adhesin Length = 160 Score = 27.6 bits (61), Expect = 0.026 Identities = 17/59 (28%), Positives = 22/59 (37%), Gaps = 5/59 (8%) Query: 112 MTATAAMTATTVMTATGMAAATAMTGGATGSGGTTV----AVRMDGFAAPAHRRTPLHA 166 M A M A +++ A A A G TG+ TV VR+ A R L Sbjct: 1 MKKLAIMAAASMVFAVSSAHAGFTPSGTTGTTKLTVTEECQVRVGDLTV-AKTRGQLTD 58
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (256), Expect = 2e-28 Identities = 73/246 (29%), Positives = 108/246 (43%), Gaps = 21/246 (8%) Query: 1 MTGAGHGIGLATAQALAADGYKIVAVDRDRGALEAADLPAGSLLVEH---------DLAA 51 +TGA GIG A A+ LA+ G I AVD + LE + H D AA Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVV-SSLKAEARHAEAFPADVRDSAA 71 Query: 52 VNSDVLATLPEDVRVGVLVNNVGVMDGRSFLELPVADAARVLQTNIVGSWAVTRAVVDHM 111 ++ E + +LVN GV+ L + N G + +R+V +M Sbjct: 72 IDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYM 131 Query: 112 LARSVRGSIVFNLSLHASRVRMC-PDYSMSKAALAMLMQELAVELGPAGIRVNAVSPGAI 170 + R GSIV S A R Y+ SKAA M + L +EL IR N VSPG+ Sbjct: 132 MDRR-SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 171 DTGQVPT----EEAQAHRERSAAL-----VALGRVGEPEDVAKVIAWLCSEQAGYVTGTD 221 +T + E + + + L ++ +P D+A + +L S QAG++T + Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHN 250 Query: 222 VRVDGG 227 + VDGG Sbjct: 251 LCVDGG 256
>cloacin#Cloacin signature. Length = 551 Score = 31.2 bits (70), Expect = 0.006 Identities = 38/163 (23%), Positives = 69/163 (42%), Gaps = 17/163 (10%) Query: 154 RDEADTDAASAAEAAEAAEHRAVEATNRADDADRAATEAQADRDRVQAETSGRVSSLERD 213 R + + DA EAAE RA N+A++ E QA +V + + + Sbjct: 305 RRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVYNSRKSELDAANKT 364 Query: 214 HAHALAELRA------EHAAQLHDLYRDHAQALADLRVDHAAVLATERQAAAEARADARG 267 A A+AE++ + A H +++ +A L+ A +QAA +A A + Sbjct: 365 LADAIAEIKQFNRFAHDPMAGGHRMWQ-----MAGLKAQRAQTDVNNKQAAFDAAAKEKS 419 Query: 268 RAERAEAHADSLAADNTRLHTEVDRLRAQLDTLRAEQARPQDG 310 A+ A L++ + D+ R+ + L E+ +P+ G Sbjct: 420 DADAA------LSSAMESRKKKEDKKRSAENNLNDEKNKPRKG 456
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.7 bits (194), Expect = 3e-19 Identities = 32/110 (29%), Positives = 58/110 (52%), Gaps = 1/110 (0%) Query: 6 VCEDQESIRTILVRGLRQAGYEVVVAHDGREALRQFSPDNNISVIIMDIGLPDADGRDVV 65 V +D +IRT+L + L +AGY+V + + R + + +++ D+ +PD + D++ Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVMPDENAFDLL 66 Query: 66 QALKSAGQHAPVLFLTALDATHDHLAGFAAGADDYVTKPFDLKVLLARLE 115 +K A PVL ++A + + GA DY+ KPFDL L+ + Sbjct: 67 PRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 27.0 bits (60), Expect = 0.031 Identities = 8/34 (23%), Positives = 15/34 (44%) Query: 168 FLDRVSRRAGLDSAASRRATEAVLETLVERVAEG 201 + +V+ L S A +AV + +A+G Sbjct: 7 LIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKG 40
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 48.9 bits (116), Expect = 2e-09 Identities = 28/137 (20%), Positives = 52/137 (37%), Gaps = 5/137 (3%) Query: 3 RDTKQRMTESAALSLRQRGLAATSFTDVLAASGAARGAIYHHFPGGKNDLAEQAVAWTGR 62 ++T+Q + + A Q+G+++TS ++ A+G RGAIY HF K+DL + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHF-KDKSDLFSEIWELSES 68 Query: 63 RVRAEFESIGGDDPDAVLRSFIELIGPVVAKAAGGTGCAVAAVTV----EASPDQPALSA 118 + P L E++ V+ + + E + + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 119 AADTAFRSWIDVLEARL 135 A D +E L Sbjct: 129 AQRNLCLESYDRIEQTL 145
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.9 bits (88), Expect = 6e-05 Identities = 57/262 (21%), Positives = 88/262 (33%), Gaps = 16/262 (6%) Query: 64 AGLLVDRFTRRRMMVVAGAARLVLFMSIPVAQRFGVLTIEQLLLVVAVSGGFTLLYDVAL 123 G L DRF RR +++V+ A V + + A VL I +++ G T Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV------AGITGATGAVA 116 Query: 124 QGYLPILLPGHELLRGNAAVETSRSTSQVIGPALGGAL---SSAFGATYAVALNATSFLG 180 Y+ + G E R + V GP LGG + S A ALN +FL Sbjct: 117 GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLT 176 Query: 181 SILSVMSVRTDEPPPEPRSPGDTVVGRLREGFAFVLTHDLLRPLTLCAAVRNLGITVTKT 240 + E R P F + ++ L + L V Sbjct: 177 GCFLL-----PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAA 231 Query: 241 VIFLYAYRALHLSVHTTGVILATGAVT-SVLGASVAGRAVRRFGYGRTLLFTVSEGVMWL 299 + ++ H T G+ LA + S+ A + G R G R L+ + Sbjct: 232 LWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY 291 Query: 300 MAPLALLGHPAAVLGVIVTFAS 321 + LA ++V AS Sbjct: 292 IL-LAFATRGWMAFPIMVLLAS 312
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.4 bits (110), Expect = 3e-08 Identities = 35/162 (21%), Positives = 64/162 (39%), Gaps = 12/162 (7%) Query: 2 RVVIAEDSVLLREGLRRLLTDAGCEVVATVGDGPGLVDAVVTHQPDVSVVDVRMPPSHRD 61 +++A+D +R L + L+ AG +V + L + D+ V DV MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMP---DE 60 Query: 62 EGLRAAIRARSEVTGSPILVLSQYVEKQYAAELLADGAGAVGYLLKDRVADVREFVDAVR 121 R + P+LV+S A + A GA YL K D+ E + + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIK--ASEKGAYDYLPKPF--DLTELIGIIG 116 Query: 122 RVAAGGTVMDPEVVAQLLVRNRRNDPMSALTPREREVLTLMA 163 R A ++L ++ P+ + +E+ ++A Sbjct: 117 RALA----EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 41.2 bits (96), Expect = 9e-06 Identities = 24/121 (19%), Positives = 42/121 (34%), Gaps = 16/121 (13%) Query: 288 AAPREVRPRLVEPIARDVHRSEPT-----ATPSTNRPHATSAAPSTTAPRTTPPKLPTST 342 +P++ + V+P A ++PT TN A + P+ + ST Sbjct: 1129 VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT-ADTEQPAKETSSNVEQPVTEST 1187 Query: 343 AASTTAAPPVTPGSSGSSGS-----SASTTPPKAR-----APQPTATIPPSVSVPPGSAT 392 +T + P ++ + + S S+ PK R P P + S S Sbjct: 1188 TVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV 1247 Query: 393 A 393 A Sbjct: 1248 A 1248
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 70.8 bits (173), Expect = 9e-16 Identities = 40/199 (20%), Positives = 62/199 (31%), Gaps = 38/199 (19%) Query: 63 LPSVVTISEESSSEAGTGSGTIIRSDGHILTNNHVVSGASDGGTLTVTLQDGRTFDA--- 119 V I E+ + SG ++ +LTN HVV D Sbjct: 87 YAPVTYIQVEAPTGTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPN 145 Query: 120 ------QVVGTDPSSDLAIIKINA--------SGLTAATFGNSDSLSIGELVVAVGSPLG 165 Q+ DLAI+K + + AT N+ + + + G P Sbjct: 146 GGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD 205 Query: 166 LNGTVTSGIVSAVHRPVRTGDSTVQDQQNTVLDAIQTDAPINPGNSGGPLVNSRGEIIGV 225 + T A+Q D GNSG P+ N + E+IG+ Sbjct: 206 KPVATMW-----ESKGKITYLKGE---------AMQYDLSTTGGNSGSPVFNEKNEVIGI 251 Query: 226 NSAIATVGGGGGSPFGGSQ 244 + GG + F G+ Sbjct: 252 HW------GGVPNEFNGAV 264
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 118 bits (296), Expect = 3e-37 Identities = 57/138 (41%), Positives = 71/138 (51%), Gaps = 12/138 (8%) Query: 1 MKGFKQFLMRGNVVDLAVAVVVGTAFTAVVTSLVKTIFTPLIAAIFGKPDFSALTFTLN- 59 +K F++F MRGNVVDLAV V++G AF +V+SLV I P + + G DF TL Sbjct: 4 IKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLRD 63 Query: 60 ------GSVFRYGEFINSVIAFLSVAVVIYFVVVLPLKTINDRRARGQIPPEEDPVLTDE 113 V YG FI +V FL VA I+ + L K R + P P T E Sbjct: 64 AQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLN-----RKKEEPAAAPAPTKE 118 Query: 114 ARLLTEIRDLLAERRPTS 131 LLTEIRDLL E+ S Sbjct: 119 EVLLTEIRDLLKEQNNRS 136
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 28.4 bits (63), Expect = 0.043 Identities = 14/80 (17%), Positives = 20/80 (25%), Gaps = 4/80 (5%) Query: 328 PRPGELSNDPDVPVEPDPAA---GPVAPSIPAPASGAAAATAPRPSIPPPGEQVPFDPAG 384 E +P + P P P P+ P E P P Sbjct: 68 VVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRD-VKPVESRPASPFE 126 Query: 385 PDRTSASASPPRSNAPSRPA 404 + S + A S+P Sbjct: 127 NTAPARLTSSTATAATSKPV 146
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 39.7 bits (92), Expect = 3e-05 Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Query: 361 LVSTTGSSSDPSRRLLIQAGTRDQQARAGQPAATAGPSPGASARADGAGSPAPTSMPASA 420 +V+T G S + + +Q R A A P P S + A +PAP P + Sbjct: 291 VVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTR 350 Query: 421 STPEPGSGLAPE--PGSGLAPGSAPQPAPAP 449 PEP L P+ P + PG+ P P Sbjct: 351 PNPEPDPDLNPDANPDTDGQPGTRPDSPAVP 381
>cloacin#Cloacin signature. Length = 551 Score = 25.8 bits (56), Expect = 0.011 Identities = 15/37 (40%), Positives = 16/37 (43%), Gaps = 5/37 (13%) Query: 28 GWG-----WGGWGGHRHHWGRWGHRGHGGWGGWGGWG 59 GW WGG G HWG G+GG G G G Sbjct: 38 GWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGG 74
>cloacin#Cloacin signature. Length = 551 Score = 32.0 bits (72), Expect = 0.003 Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 7/77 (9%) Query: 100 VSGINPGNNLGQAVNHSGT---VNAAATALEFGVPAIAVSLQTSSTWREGTVVAAKSSAA 156 SG G G + SGT ++A A + FG PA++ T ++A + +A Sbjct: 59 GSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALS----TPGAGGLAVSISAGALSA 114 Query: 157 YVADLVARLEGRSQHGA 173 +AD++A L+G + G Sbjct: 115 AIADIMAALKGPFKFGL 131
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 35.6 bits (82), Expect = 6e-04 Identities = 10/36 (27%), Positives = 21/36 (58%) Query: 526 PQYVLEMAKQRPRGYTSATDHLRVELVHTFGGLYID 561 P ++++ ++ +D LR+ L+ +GGL+ID Sbjct: 117 PDFLIKRWQEGKMLDAWFSDILRLFLLCKYGGLWID 152
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 5e-15 Identities = 32/167 (19%), Positives = 63/167 (37%), Gaps = 12/167 (7%) Query: 63 ETPAKILDAALGCIAARGPAKMSLRDVSAAAEVSRGTLYRYFKTKGELLTAISDHVRRGV 122 ET ILD AL + +G + SL +++ AA V+RG +Y +FK K +L + I + + Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 123 SAALDEAVAGQPADS-GRLRATVDAIMHYGDDHPEVSRVI-----EAEPAFALQFIRDIF 176 E A P D LR + ++ ++ + E + ++ Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 177 PSFVAQMTELLAPVLDDLGIVQEGTVRR----EVLAELLLRATSSLY 219 + + + + L ++ + A ++ S L Sbjct: 131 RNLCLESYDRIEQTLKHC--IEAKMLPADLMTRRAAIIMRGYISGLM 175
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (290), Expect = 4e-33 Identities = 87/282 (30%), Positives = 136/282 (48%), Gaps = 34/282 (12%) Query: 5 LEGKVAFITGAARGQGRSHAVRLAQEGADIIAIDIVEQIESNPYPLSTPEDLAETVTLVE 64 +EGK+AFITGAA+G G + A LA +GA I A+D PE L + V+ ++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD------------YNPEKLEKVVSSLK 53 Query: 65 KLGRRIIATKADVRERDQLREAVNKGVAELGRLDIVVANAGILPMAMGDPQATDFIDAV- 123 R A ADVR+ + E + E+G +DI+V AG+L + + + +A Sbjct: 54 AEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATF 113 Query: 124 DVDLIGVMNAVAVSVPHLPDR--SSIIVTGSTAAMMPNTTDNPAMGPGSAGYGWAKKILI 181 V+ GV NA ++ DR SI+ GS A +P T A Y +K + Sbjct: 114 SVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRT--------SMAAYASSKAAAV 165 Query: 182 GYVEEMALHLAPKFIRVNAIHPTNVNTHLLHNDGLYAQFRPDLENPTREDVEPAFVTFQA 241 + + + L LA IR N + P + T + + L+A EN + ++ + TF+ Sbjct: 166 MFTKCLGLELAEYNIRCNIVSPGSTETDMQWS--LWAD-----ENGAEQVIKGSLETFK- 217 Query: 242 MPIPY---VEPVDISNLVLFLASDESRYITGQQIRVDAGSLL 280 IP +P DI++ VLFL S ++ +IT + VD G+ L Sbjct: 218 TGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>PERTACTIN#Pertactin signature. Length = 922 Score = 24.7 bits (53), Expect = 0.029 Identities = 12/36 (33%), Positives = 13/36 (36%) Query: 19 GPIASPPDAPPPSTVTPPPAEPRPQPSPRPRDIRPP 54 GP P PP PP PQ P +PP Sbjct: 578 GPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Score = 24.3 bits (52), Expect = 0.037 Identities = 12/47 (25%), Positives = 18/47 (38%) Query: 13 ADPTDHGPIASPPDAPPPSTVTPPPAEPRPQPSPRPRDIRPPLAARP 59 A+ + P P P +P PQP P+ +PP +P Sbjct: 554 ANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQP 600
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 87.8 bits (217), Expect = 1e-22 Identities = 75/262 (28%), Positives = 115/262 (43%), Gaps = 14/262 (5%) Query: 8 AGRLAGRVAVVTGAGQGLGRAIAAALADEGAAVALLGRTESKVVDAAEELAGKGARVLAL 67 A + G++A +TGA QG+G A+A LA +GA +A + K+ L + A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 68 RCDVAERADAQAAVAATLAAFGGVDILVNNAQGGNNTVRI-PTVDATDAELLESFETGPL 126 DV + A A G +DILVN A +R +D E +F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVA----GVLRPGLIHSLSDEEWEATFSVNST 118 Query: 127 GSVHMMQACFEALRDSGHGAVVNFGSGIGVRGAPGLLGYAMAKEAIGGLTKVTAIEWGRY 186 G + ++ + + D G++V GS + YA +K A TK +E Y Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 187 GIRVNQVCPAA------WSPAAEEYMKQSPERWELQRRQT--PLRRLGDPYADIGRAIVS 238 IR N V P + WS A+E + + L+ +T PL++L P +DI A++ Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKP-SDIADAVLF 237 Query: 239 LVSDDMQYLTGATLMLDGGQIL 260 LVS ++T L +DGG L Sbjct: 238 LVSGQAGHITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.1 bits (223), Expect = 2e-23 Identities = 63/252 (25%), Positives = 104/252 (41%), Gaps = 6/252 (2%) Query: 7 GKTAIVTGGSSGIGLASAEAFVAEGAHVVIGDIQDERGRAAAERLGDAALYVHT---DVS 63 GK A +TG + GIG A A ++GAH+ D E+ L A + DV Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 64 DDDQVANLVDTAVRHFGGLDIMFNNASGAGDQAGLVDLGPDGLDRSLRLIVGSAVSGHRH 123 D + + R G +DI+ N +G + L + + + + + R Sbjct: 68 DSAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 124 AARVFIEQGRGGSIITTSSGSGLRGGLGQPSYTIGKHAVIGVVRHAAAELGRHGIRSNAI 183 ++ +++ R GSI+T S +Y K A + + EL + IR N + Sbjct: 127 VSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 184 CPGITMTPV-LGMGIARDRRPAFMEHLAEALRDEQPAGRVGQPEDIAAAVVFLASDLSRF 242 PG T T + + + ++ E + P ++ +P DIA AV+FL S + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 243 VNGVILPVDGGA 254 + L VDGGA Sbjct: 246 ITMHNLCVDGGA 257
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.3 bits (58), Expect = 0.027 Identities = 13/42 (30%), Positives = 20/42 (47%) Query: 21 TLANPHRLRVLAALADERNYVSRLARDLDISRALLQVHLRKL 62 LA +LAAL R + A L ++R L+ +R+L Sbjct: 432 VLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 128 bits (322), Expect = 7e-34 Identities = 101/422 (23%), Positives = 175/422 (41%), Gaps = 26/422 (6%) Query: 32 AQGGYTHRQIMVILSGLLLGMFLAALDQTVVSTAIYRIGESLHGLTAQA-WVTTAFLITS 90 +Q H QI++ L L F + L++ V++ ++ I + A WV TAF++T Sbjct: 6 SQSNLRHNQILIWLCIL---SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 91 TIATPLYGKLSDLYGRKPFFLFAIAVFITGSALCTFATSMY-MLAAFRAVQGIGAGGLFS 149 +I T +YGKLSD G K LF I + GS + S + +L R +QG GA + Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 150 LALAIVGDIIPPRERAKYQGYFMAVFGTSSVLGPVVGGALAGQDTLLGVAGWRWIFLINV 209 L + +V IP R K G ++ +GP +GG +A W +L+ + Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY--------IHWSYLLLI 174 Query: 210 PIGIGALVVVARVLHISHERREHRIDYPGALTLIVALVPLLIVAEQGREWGWGAGSSLVC 269 P+ V L R + D G + + V +V ++ + L+ Sbjct: 175 PMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYS-ISF-----LIV 228 Query: 270 YAIGLVGIAAFVVAERRAKDDALLPPRLFRNGVFAVGSAQSAIIGIGMFGGITLLPLYLQ 329 + + V R D + P L +N F +G II + G ++++P ++ Sbjct: 229 SVLSFL----IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMK 284 Query: 330 LVKGNSPTKAG-LLTLPLVLGIMLLSLVAGQITSRTGRYKILPVIGSALLVVGMLLLWRL 388 V S + G ++ P + +++ + G + R G +L IG L V L L Sbjct: 285 DVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVL-NIGVTFLSVSFLTASFL 343 Query: 389 SADSSLVYVDLAMFVVGAGLGLNMQTIVLAMQNAVPPRDIGVATSSTTFFRQLGGTLGVA 448 +S + +FV+G GL I + +++ ++ G S F L G+A Sbjct: 344 LETTSWFMTIIIVFVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIA 402 Query: 449 VF 450 + Sbjct: 403 IV 404
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.7 bits (235), Expect = 4e-25 Identities = 79/269 (29%), Positives = 117/269 (43%), Gaps = 23/269 (8%) Query: 32 LDGRTAFITGVARGQGRAHAVRLAREGADIIGVDICADIASMDYPNASAADLAETVELVE 91 ++G+ AFITG A+G G A A LA +GA I VD + E V Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD-------------YNPEKLEKVVSSL 52 Query: 92 KLGGRIV-ARQADVRDFAGLSAAFQEGLAAFGRVDIVIANAGIIRLSP-EADPFTEWQDV 149 K R A ADVRD A + G +DI++ AG++R + EW+ Sbjct: 53 KAEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT 112 Query: 150 IDTNLTGVFKTVRAALPALIEGGRGGAIVLTSSSAGLKGTGSPDAGPQAYTAAKRGLVGL 209 N TGVF R+ +++ R G+IV S+ G P AY ++K V Sbjct: 113 FSVNSTGVFNASRSVSKYMMD-RRSGSIVTVGSNPA----GVPRTSMAAYASSKAAAVMF 167 Query: 210 MQVLANDLAKHWIRVNTIHPTGVATGMTMNESMAKLLAESDNATAAMQNALPI---EILQ 266 + L +LA++ IR N + P T M + + AE + I ++ + Sbjct: 168 TKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAK 227 Query: 267 PEDISDTVAWLVSDAAKYVTGVALPIDAG 295 P DI+D V +LVS A ++T L +D G Sbjct: 228 PSDIADAVLFLVSGQAGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.0 bits (150), Expect = 4e-14 Identities = 32/202 (15%), Positives = 71/202 (35%), Gaps = 13/202 (6%) Query: 2 RGRPRDPDLPARVLDAALAEYARSGWAGFTMHAVAGRAGVGKSSMYLRWPTKEQLLVDAI 61 + + + +LD AL +++ G + ++ +A AGV + ++Y + K L + Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 62 DAYTRPL--VVDHDTGSLRGDVLALASSLLAHFLD-----PMGWVTVRIAVDAAVESVDL 114 + + + GD L++ +L H L+ + + I ++ Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 115 GGFHERIVTKHNDAAQRIVD---RAIGRGELPAGVDGRPLLEGLFGGV--LLHTLALPPS 169 + ++ RI I LPA + R + G + L+ P Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183 Query: 170 EHAAARTDLAAHVTPLVDLLLR 191 + +V L+++ L Sbjct: 184 SFDLK-KEARDYVAILLEMYLL 204
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.4 bits (110), Expect = 3e-08 Identities = 20/87 (22%), Positives = 33/87 (37%), Gaps = 4/87 (4%) Query: 15 AGTGAQAVRLARHLRPDVVLMDIRMPIMDGLEAM-RIIAADPGTAATRVLVVTTFDQDEH 73 A R D+V+ D+ MP + + + RI A P VLV++ + Sbjct: 33 TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPD---LPVLVMSAQNTFMT 89 Query: 74 VFAALRGGASGFVLKDTRPEDLLAAIR 100 A GA ++ K +L+ I Sbjct: 90 AIKASEKGAYDYLPKPFDLTELIGIIG 116
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.3 bits (63), Expect = 0.012 Identities = 24/81 (29%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 6 SAGTAAWGPHLAVLILAGVLATGSWLRRRRPSTEWRARGALPAPLGRPAARRITLTALAV 65 S +GP + + +LAG +A LR+ + + R L PL AR + A Sbjct: 220 SDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRR-LLHLPLIGRIARGLNTARYAR 278 Query: 66 RRRPAELWRLAVLAASAVVLL 86 L++L ASAV LL Sbjct: 279 --------TLSILNASAVPLL 291
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 2e-13 Identities = 28/161 (17%), Positives = 50/161 (31%), Gaps = 10/161 (6%) Query: 17 RRLRSDAARNVESLVTAARALFDERGTE-VPLDEIARRAGVGNATLYRNFPTRGDLLVAV 75 R+ + +A + ++ A LF ++G L EIA+ AGV +Y +F + DL + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 76 YSEEVDALCGHGAALLETTPP------GDALFAWLDLFVVHAATRRALAL---AALSQGP 126 + + P + L L+ V R + + G Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 127 DERRGKLAEGWHASMRSTLAALLAPAQEAGAVRPDLTAADL 167 + + L EA + DL Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRA 163
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 26.8 bits (59), Expect = 0.032 Identities = 16/49 (32%), Positives = 23/49 (46%), Gaps = 7/49 (14%) Query: 50 GVAAIRSAALALGEANPVGHHVTNIVLTEQA-------DGRVRARSKGI 91 G+ A + +A +GE+NPV + + V A D RV KGI Sbjct: 289 GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGI 337
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.5 bits (185), Expect = 2e-18 Identities = 61/232 (26%), Positives = 96/232 (41%), Gaps = 11/232 (4%) Query: 2 FAARGFGVVAVDLDEAGLSALIGRSASEQVVP--LVGDVSREETGTAMARLALDRFGRLD 59 A++G + AVD + L ++ +E DV + G +D Sbjct: 28 LASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAIDEITARIEREMGPID 87 Query: 60 VAVLNAGIGGTLPWEDADAIDRLDRIFAVNVRGVAIGIRSVVPAMRAAGGGAIVVTASSA 119 + V AG+ + + + + F+VN GV RSV M G+IV S+ Sbjct: 88 ILVNVAGVLRPGL-IHSLSDEEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNP 146 Query: 120 GLQGEPGNWAYNASKAAVINMVRAAALDHAAQRIRINAVAPGLSETPLTARHRAEPESAA 179 AY +SKAA + + L+ A IR N V+PG +ET + A+ A Sbjct: 147 AGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAE 206 Query: 180 AVGR--------RIPMQRWGQAREHAAAIWFLASPEASYITGTTLVADGGLT 223 V + IP+++ + + A A+ FL S +A +IT L DGG T Sbjct: 207 QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGAT 258
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 32.7 bits (74), Expect = 5e-04 Identities = 12/69 (17%), Positives = 23/69 (33%), Gaps = 2/69 (2%) Query: 12 AEVTMPQVAQVALVSEATAYRYFPDLVSLIQEALVGLWPQPAQALAPIAGST--DPGERV 69 + ++ ++A+ A V+ Y +F D L E + DP + Sbjct: 30 SSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVL 89 Query: 70 AFACEHLLR 78 H+L Sbjct: 90 REILIHVLE 98
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 127 bits (320), Expect = 5e-34 Identities = 87/422 (20%), Positives = 166/422 (39%), Gaps = 25/422 (5%) Query: 22 SSTTSSKAAILTLACVAQFMVILDVSIVNVALPAMRHGLGLSAAGQQWIVTAYTLGFAGL 81 S + IL C+ F +L+ ++NV+LP + + A W+ TA+ L F+ Sbjct: 6 SQSNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIG 65 Query: 82 LLLGGRVADLVGVRRAFLAGLAGFTLASLAGGLATSGA-VLIAARAGQGVCAAFLAPATL 140 + G+++D +G++R L G+ S+ G + S +LI AR QG AA PA + Sbjct: 66 TAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALV 124 Query: 141 TLITTTFTEPTARTRAVGAWSTVTTTGGAAGAVLGGVLTQYLGWRWVLFVNVPAGAAVLA 200 ++ + R +A G ++ G G +GG++ Y+ W ++L +P + Sbjct: 125 MVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITV 182 Query: 201 VAGGRIPAADGRAADALRRLDLPGAAAVFAALTALVYGV-VNTETHGLADPRVAVPLAAA 259 ++ + R D+ G + + + + + L + Sbjct: 183 PFLMKLLKKEVRIKG---HFDIKGIILMSVGIVFFMLFTTSYSISF----------LIVS 229 Query: 260 VLLLAGFVAIEFTAAQPLVPLAMLRRRTLAGGNLIMIFIGGALFPMWFLLSLYLQQVLHL 319 VL FV P V + + G L I G + ++ ++ V L Sbjct: 230 VLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQL 289 Query: 320 HAVRTGWC-LLPGALSIIVGARISVRLLGTLGPRRLLVIGMALSTAGFAWLSRVGVDGDY 378 G + PG +S+I+ I L+ GP +L IG+ + F S + Sbjct: 290 STAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL----LE 345 Query: 379 HTDVLAPFLLTALGLGLAITPTTVT--ATQGIDRAHSGLAAGLVNTSRQVGGALGLAALA 436 T ++ + GL+ T T ++ + + + +G L+N + + G+A + Sbjct: 346 TTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405 Query: 437 TL 438 L Sbjct: 406 GL 407
>cloacin#Cloacin signature. Length = 551 Score = 41.2 bits (96), Expect = 8e-06 Identities = 41/118 (34%), Positives = 48/118 (40%), Gaps = 16/118 (13%) Query: 270 GNGGHVHLSLWGDGDGDDGSGVGGSGVGGSGDDGGAGGDSAARPGGYLGGYGAGPGTAAG 329 G G H + G+ G G GVGG D G+G S P G GG G+G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASD-GSGWSSENNPWG--GGSGSGIHWG-- 57 Query: 330 GVVVGGSSAGGGWHGGGRVNLMGGGNGPGGLTATGEAFAAGILARLPALMALGAPSVA 387 GGS G G G GGG+G GG A AA + PAL GA +A Sbjct: 58 ----GGSGHGNGGGNGNS----GGGSGTGG---NLSAVAAPVAFGFPALSTPGAGGLA 104 Score = 34.7 bits (79), Expect = 0.001 Identities = 27/96 (28%), Positives = 38/96 (39%), Gaps = 12/96 (12%) Query: 305 AGGDSAARPGGYLGGYGAGPGTAAGGVVVGGSSAGGGW------------HGGGRVNLMG 352 +GGD G G G G V GG+S G GW G G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 353 GGNGPGGLTATGEAFAAGILARLPALMALGAPSVAS 388 GNG G + G + G L+ + A +A G P++++ Sbjct: 62 HGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALST 97 Score = 31.2 bits (70), Expect = 0.011 Identities = 35/122 (28%), Positives = 45/122 (36%), Gaps = 25/122 (20%) Query: 280 WGDGDGDDGSGVGGSGVGGSGDDGGAGGDSAARPGGYLGGYGAGPGTAAGGVVVGGSSAG 339 WG G G GGSG G G +G +GG S G +A V G A Sbjct: 46 WGGGSGSGIHWGGGSGHGNGGGNGNSGGGSG----------TGGNLSAVAAPVAFGFPA- 94 Query: 340 GGWHGGGRVNLMGGGNGPGGLTATGEAFA---AGILARLPALMALGAPSVASYLRLVPSQ 396 L G G ++ + A + A I+A L G VA Y ++PSQ Sbjct: 95 ----------LSTPGAGGLAVSISAGALSAAIADIMAALKGPFKFGLWGVALY-GVLPSQ 143 Query: 397 WA 398 A Sbjct: 144 IA 145 Score = 29.3 bits (65), Expect = 0.049 Identities = 18/66 (27%), Positives = 24/66 (36%), Gaps = 2/66 (3%) Query: 272 GGHVHLSLWGDGDGDDGSGVGGSGVGGSGDDGGAGGDSAARPGGYLGGYGAGPGTAAGGV 331 GG WG G G G G+ GGSG G + A P + + PG V Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSG--TGGNLSAVAAPVAFGFPALSTPGAGGLAV 105 Query: 332 VVGGSS 337 + + Sbjct: 106 SISAGA 111
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 109 bits (273), Expect = 3e-30 Identities = 77/256 (30%), Positives = 123/256 (48%), Gaps = 20/256 (7%) Query: 72 LDGRVAIVTGASSGLGVDFARGLAEAGADVVLGARRVERLEATAKLVEAAGRRALAVAVD 131 ++G++A +TGA+ G+G AR LA GA + E+LE ++A R A A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 132 VADPAGAERVAAAAMEAFGRVDVLVNNAGIGTAVPALKETPEQFRTVLDVNLSGCYWMAQ 191 V D A + + A G +D+LVN AG+ + E++ VN +G + ++ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 192 AAARVM--RPGSSIVNISSVLGLTTAGLPQ---AAYTASKAGLIGLTRDLAQQWTGRQGI 246 + ++ M R SIV + S AG+P+ AAY +SKA + T+ L + I Sbjct: 126 SVSKYMMDRRSGSIVTVGS----NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE-YNI 180 Query: 247 RVNALAPGFFRSEM-----TDEYRP-----GYIETQLTRVLDGRFGEPAELTAALLFLAS 296 R N ++PG ++M DE G +ET T + + +P+++ A+LFL S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 297 DAGSFVTGQTLVVDGG 312 +T L VDGG Sbjct: 241 GQAGHITMHNLCVDGG 256
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 25.9 bits (57), Expect = 0.039 Identities = 22/107 (20%), Positives = 37/107 (34%), Gaps = 26/107 (24%) Query: 5 LLAADLAARLDADLVLIATMDRWSRWARWTAGVYCAFGVETVMCAARIAEEETREELQRR 64 L LA ++AD+ +I T G +G E + EE R+ + Sbjct: 217 LAGEKLAEEVNADIFMILTD---------VNGAALYYGTEKEQWLREVKVEELRKYYEEG 267 Query: 65 LRSLLDLVGVDWSVQWATGS--PR-RAAVRYTRRHPDAMVILRPERA 108 + GS P+ AA+R+ + +I E+A Sbjct: 268 --------------HFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKA 300
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 99.4 bits (247), Expect = 2e-26 Identities = 77/254 (30%), Positives = 116/254 (45%), Gaps = 18/254 (7%) Query: 12 VAVVTGGGRGIGAACSVALARLGWDVCVGYRSDSAAAERVVGACRDLGVTAASAAADLAH 71 +A +TG +GIG A + LA G + + E+VV + + A + AD+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHI-AAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 72 PSAVTDLFAA-ADRLGPVTALVNNAGVVAPAARIDEMDHARLHTMFTVNITAAFLCAGAA 130 +A+ ++ A +GP+ LVN AGV+ P I + F+VN T F + + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 131 VRRMSTRHGGPGGSIVNVSSAAARIGSPGTYVD-YAASKAALDTMTLGLAQEVAAEGIRV 189 + M R G SIV V S A G P T + YA+SKAA T L E+A IR Sbjct: 128 SKYMMDRRSG---SIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 190 NGVRPGYIDTEIHAS-----GGDPDRARRLGAT----VPLGRPGRADEVAAAVAWLCTAA 240 N V PG +T++ S G + T +PL + + ++A AV +L + Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 241 ASYVTGAVLDVSGG 254 A ++T L V GG Sbjct: 243 AGHITMHNLCVDGG 256
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.6 bits (79), Expect = 6e-04 Identities = 19/95 (20%), Positives = 30/95 (31%), Gaps = 4/95 (4%) Query: 333 TPLRIPAPAPSSDGPALAVKAPAVPAPAVPAPALPAPALPAPALPAPAIPAPALPASAVK 392 P P P P A V P P P P P + PAS + Sbjct: 75 EPEPEPEPIPEPPKEAPVVIEKPKPKPKPK----PKPVKKVEQPKRDVKPVESRPASPFE 130 Query: 393 SSAVSASAVSASAVSPDRPAAPPEARSVPHARPEP 427 ++A + S + + +P + +R +P Sbjct: 131 NTAPARPTSSTATAATSKPVTSVASGPRALSRNQP 165 Score = 33.4 bits (76), Expect = 0.001 Identities = 22/106 (20%), Positives = 28/106 (26%), Gaps = 1/106 (0%) Query: 328 LNRHETPLRIPAPAPSSDGPALAVKAPAVPAPAVPAPALPAPALPAPALPAPAIPAPALP 387 L P+ + AP+ P AV+ P P P P P A P P P Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPK-P 101 Query: 388 ASAVKSSAVSASAVSASAVSPDRPAAPPEARSVPHARPEPGGGTGP 433 K RPA+P E + Sbjct: 102 KPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATS 147
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.9 bits (166), Expect = 5e-14 Identities = 34/120 (28%), Positives = 53/120 (44%), Gaps = 2/120 (1%) Query: 558 TILVVEDERAMREVTRRLLARNGYQVITAADGHRAVELAVSHPAEIHLLLTDVVMPQVLG 617 TILV +D+ A+R V + L+R GY V ++ + L++TDVVMP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMPDENA 62 Query: 618 RTVATLVRRHRPGIRVLFMSGYAYPVLAHNGTLDPGLTLLGKPFSEQMLLAKVRDVLDNP 677 + +++ RP + VL MS + A + L KPF L+ + L P Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 5e-18 Identities = 27/142 (19%), Positives = 52/142 (36%), Gaps = 10/142 (7%) Query: 1 MDAPTALVVDDNEMLRALLGRILCAEGFRVSAAGSVEEAL-LLDAAAHDVLLIDLRLGGR 59 M T LV DD+ +R +L + L G+ V + + A D+++ D+ + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 SGADLIDELRRIDPAVTARCLVLTGAAGLDPVPAGL-----PVVTKPFTADELVAAVREV 114 + DL+ +++ P LV++ + KPF EL+ + Sbjct: 61 NAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 115 LRVDRGHGADRRHEADRRHEAD 136 L + + E D + Sbjct: 119 LAEPK--RRPSKLEDDSQDGMP 138
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 0.005 Identities = 29/192 (15%), Positives = 54/192 (28%), Gaps = 15/192 (7%) Query: 1162 QRGPARPAAEPATPARPAAAEPAAPAPVAAFAAPHQSP-APGGPVRPG------AGQPGT 1214 +R TP A P+ P+ A ++P P P P A Sbjct: 987 KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046 Query: 1215 RPQPTAAQSHQP--PAPNQSVPPLQAAPPLQTAPQH----QTAPQHQTAQPPDRGGWSSP 1268 + +A ++ Q Q+ + + Q + ++ Sbjct: 1047 ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV 1106 Query: 1269 GDAGWQAAESLRQPSSGGVTRSGLPVRVPMTHLVPGSAEPAPSRRPAETSTRSPEAVGGR 1328 E+ + VT P + + P AEPA P + + P++ Sbjct: 1107 EKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQP-QAEPARENDPTV-NIKEPQSQTNT 1164 Query: 1329 LASFYQGVRQGR 1340 A Q ++ Sbjct: 1165 TADTEQPAKETS 1176
>cloacin#Cloacin signature. Length = 551 Score = 37.4 bits (86), Expect = 2e-04 Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 4/41 (9%) Query: 737 PWGGSGGSGPGGFGSGGFG----SGSAGQGAGRAGGGSAPA 773 PWGG GSG G G G +G++G G+G G SA A Sbjct: 45 PWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85
>cloacin#Cloacin signature. Length = 551 Score = 29.3 bits (65), Expect = 0.037 Identities = 21/56 (37%), Positives = 26/56 (46%), Gaps = 1/56 (1%) Query: 286 GAGAGAGAGAGAGAGAGAGARAG-AGAGAAPHGGGGMRAVVVAVGARRGSAPGPAG 340 G G+G+G G G+G G G G +G G+ G A VA G S PG G Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.5 bits (84), Expect = 2e-04 Identities = 28/119 (23%), Positives = 34/119 (28%), Gaps = 6/119 (5%) Query: 369 PPPASGPWPVGPPPPASAFRPAVSPPPTIPPPPPLPASRLTPLPPAPLPPSAPPPSTPPA 428 P PA P AV PPP P P P P PP P P P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPE-PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 102 Query: 429 PRPSAARVPPGASPPAGSQPVVSPWTYDMDEPDSRAPVRPRREPPPDPHAAGETRPRSR 487 P+P P + V + ++ AP RP + T S Sbjct: 103 PKP-----KPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Score = 34.6 bits (79), Expect = 0.001 Identities = 21/106 (19%), Positives = 27/106 (25%) Query: 347 DPAPSGGGRPSAAGGWSPSVQGPPPASGPWPVGPPPPASAFRPAVSPPPTIPPPPPLPAS 406 P + A P PPP P P P P P P P Sbjct: 46 PAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 105 Query: 407 RLTPLPPAPLPPSAPPPSTPPAPRPSAARVPPGASPPAGSQPVVSP 452 + P P S P +P + A P +S + Sbjct: 106 KPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVT 151
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 31.4 bits (70), Expect = 0.010 Identities = 25/98 (25%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 322 GTTRPATAPPPEPAGTAAGPAGT---TISPADIGVRPADVSVGSAGVSVGPAGVSVGPAD 378 G P P P G A G I + A V+VG+ ++ G V++GP Sbjct: 48 GLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLS 107 Query: 379 VSV--AAVRNASGRT--------GLAAATVDALRSLGF 406 ++ +AV + T G A+T D ++GF Sbjct: 108 KALGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGF 145
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 31.3 bits (70), Expect = 0.015 Identities = 21/83 (25%), Positives = 31/83 (37%), Gaps = 3/83 (3%) Query: 548 VVSAIGRWAPFPVGVTIAVFVLAALLFAGTIAGAGAGAWQRPAAPASDSAAGPDSDSKVA 607 VVS G P V V +A + L+ T+ A A P + + A P + + Sbjct: 372 VVSTDGVSVPKAVPVRMAAYNATTGLYEVTVPSTTAEA---PPLILTWTPASPPGNQNPS 428 Query: 608 AVTPTQPSAAAVDPTAATSPGGP 630 + TP P V A +P Sbjct: 429 STTPVVPKPVPVYEGATLTPVKA 451
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.9 bits (114), Expect = 2e-08 Identities = 51/245 (20%), Positives = 77/245 (31%), Gaps = 35/245 (14%) Query: 1 MRVLVTGAAGQLGADLCRLLEARTAEPDSPVRAWAGL----------GRAELDITDPAR- 49 M+ LVTGAAG +G + + L + V L R EL + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ----VVGIDNLNDYYDVSLKQARLELLAQPGFQF 56 Query: 50 VRAVLRDQARPAKI---QGGLVVINTAAWTDVDGAEADEAGAYAVNATGPAHLAATCAEL 106 + L D+ + V + V + + N TG ++ C Sbjct: 57 HKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 107 D-ATLVQLSTDYVFDGRATKPYETGDETD-PAGAYGRTKLAGEEAVRALLPASSYVVRTA 164 L+ S+ V+ P+ T D D P Y TK A E A + Y + Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELM--AHTYSHLYGLPAT 174 Query: 165 -----WVYGATGR------NFVKTISRLARERGAVSVVADQTGSPTWSADLAAGLLDLVA 213 VYG GR F K + L + V T+ D+A ++ L Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAM--LEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQD 232 Query: 214 SPAPP 218 Sbjct: 233 VIPHA 237
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 6e-12 Identities = 35/207 (16%), Positives = 62/207 (29%), Gaps = 19/207 (9%) Query: 31 RERKKLRTRRALRMAAIRLVAERGLDGVSVDEIAAAAEVSTRTFFNYFPTKDDAIVGIDP 90 +++ TR+ + A+RL +++G+ S+ EIA AA V+ + +F K D I Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 91 EDIREITEALVARP--LGEEPLAAVRAVMLQRAALIAPEQADLWRARLAIIRRHPHLMTA 148 I E + +PL+ +R +++ E+ R L I H Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER---RRLLMEIIFHKCEFVG 121 Query: 149 SAAS-----------WSSYENALAEAVGSRCGLDPARDPYPAVLVAAVLAIVRILSLRWQ 197 A + L + + L W Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLM--TRRAAIIMRGYISGLMENWL 179 Query: 198 ESPGAP-LADLLGQAFDSLSRGLPPPP 223 +P + L L P Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCP 206
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 150 bits (380), Expect = 1e-41 Identities = 91/401 (22%), Positives = 174/401 (43%), Gaps = 17/401 (4%) Query: 39 ILLASLDQTIVSTALPTIVGDLGGA-THLSWVVTAYLLASTVSTPVWGKLGDLYGRKILF 97 + L++ +++ +LP I D +WV TA++L ++ T V+GKL D G K L Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 98 QVSIVLFLVGSVLAGACTSMGQ-LIGFRALQGLGGGGLMIGAMTIISDLVPPRDRGRYQG 156 I++ GSV+ S LI R +QG G M +++ +P +RG+ G Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 157 LFGAVFGVSSVIGPLLGGLFVDHLSWRWVFYVNLPVGAVALVVTALALPATTNRIKHVID 216 L G++ + +GP +GG+ ++ W ++ +P+ + V + L RIK D Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 217 YLGTVLLAGATTSLVLLTSLGGTTYGWGSPEIIGLGVAGAVLLVAFVFAERRAVEPVLPL 276 G +L++ +L T T+Y + + + FV R+ +P + Sbjct: 201 IKGIILMSVGIVFFMLFT----TSYSI------SFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 277 SLFRNRVFSAAGAIGFVVGFAMFGAIVFLPLFLQVVKGVDPTESG-LQMLPVMGGLLLSS 335 L +N F G ++ + G + +P ++ V + E G + + P +++ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 336 IISGRLISQWGRYKVFPIVGTAVMTIGLFLLSFISPDIATWQLALSMFVLGVGIGSVMQV 395 I G L+ + G V +G +++ SF+ + + + +FVLG G+ V Sbjct: 311 YIGGILVDRRGPLYVL-NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTV 368 Query: 396 LVIAVQNSVDHRQMGVATSGATFFRSIGGSFGTAVFGAIFA 436 + V +S+ ++ G S F + G A+ G + + Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>cloacin#Cloacin signature. Length = 551 Score = 35.1 bits (80), Expect = 0.001 Identities = 22/54 (40%), Positives = 26/54 (48%), Gaps = 5/54 (9%) Query: 388 SGEAAPGPSAAGPGGSSENGSSGNGSS-----GNGSSGNGSSGNGSSGNGSSGG 436 +G G ++ G G SSEN G GS G GS GNG+SG GS G Sbjct: 25 TGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78 Score = 31.6 bits (71), Expect = 0.012 Identities = 12/36 (33%), Positives = 18/36 (50%) Query: 394 GPSAAGPGGSSENGSSGNGSSGNGSSGNGSSGNGSS 429 G S +G +G G +GN G+G+ GN S+ Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 31.2 bits (70), Expect = 0.015 Identities = 21/53 (39%), Positives = 24/53 (45%), Gaps = 4/53 (7%) Query: 388 SGEAAPGPSAAGPGGSSENG---SSGNGSSGNGS-SGNGSSGNGSSGNGSSGG 436 SG GP+ G GG + +G SS N G GS SG G GNG G Sbjct: 17 SGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Score = 30.1 bits (67), Expect = 0.031 Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 389 GEAAPGPSAAGPGGSSENGSSGNGSSGNGSSGNGSS 424 G + G G G G +GN G+G+ GN S+ Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83
>PF07675#Cleaved Adhesin Length = 1358 Score = 29.7 bits (66), Expect = 0.034 Identities = 27/96 (28%), Positives = 40/96 (41%), Gaps = 9/96 (9%) Query: 226 PVTLGFTWAAESRKQVVLSWDGPTGSTDGGRAELAVGPESTTVTLTVGGEAPRVDVVNNV 285 PV+ T A+ +K V L WD P+ G E+ + VT+ P DV N Sbjct: 335 PVS-NLTATAQGQK-VTLKWDAPSAKKAEGSREVKRIGDGLFVTIE-----PANDVRANE 387 Query: 286 GGIVLT--DGYGADRGYQQVDTGQFDQPEDVFTACG 319 +VL + +G + GYQ + + V A G Sbjct: 388 AKVVLAADNVWGDNTGYQFLLDADHNTFGSVIPATG 423
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 35.1 bits (80), Expect = 0.001 Identities = 47/156 (30%), Positives = 66/156 (42%), Gaps = 21/156 (13%) Query: 113 AGLVHRDLKPSNVLL--SSLGPRVIDFGIARALDAQTMLSQEIQRVGTPAFMAPEQANGE 170 AG+VH D+KP NV+ +S P VID G+ S E + T +F APE G Sbjct: 264 AGVVHNDIKPGNVVFDRASGEPVVIDLGLHSR-------SGEQPKGFTESFKAPELGVGN 316 Query: 171 -PVSAAADVFAWGGLVTYAGTGSFPFGDGP--TPVQLYRVVHREPLLDGLDPALRPIVEE 227 S +DVF + + G F P P Q R + EP +D PI Sbjct: 317 LGASEKSDVFLVVSTLLHCIEG---FEKNPEIKPNQGLRFITSEP-AHVMDENGYPI--- 369 Query: 228 AMRKDPAARPTAQELFLR-LVGMGPSTHPDPDVTRV 262 R A TA F+ ++G+ + PD + R+ Sbjct: 370 -HRPGIAGVETAYTRFITDILGVSADSRPDSNEARL 404
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.0 bits (59), Expect = 0.026 Identities = 17/50 (34%), Positives = 20/50 (40%) Query: 36 PAAAPSAADGRLTGPRGAACAPLGGEEGAPGGGDDAPGGGGDATPDAPAD 85 P AA A G + A G + G PGGGDD G+ D A Sbjct: 390 PTAAAGGAGGGEPPKKRDPSAGAGTDPGGPGGGDDGEDPFGEWLDDEVAR 439
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 39.3 bits (91), Expect = 6e-05 Identities = 16/65 (24%), Positives = 22/65 (33%), Gaps = 3/65 (4%) Query: 699 AEGAQPPSPPAHGDPPPPDRSSARPQPQTPATTNQTPAVAQPGSAP-TSTSTSPTAAAAA 757 A +Q P P + PQ T N+ P P T + +P AAA Sbjct: 463 ASDSQTPDAKPGNKAVPGKGQA--PQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAA 520 Query: 758 AAAMS 762 M+ Sbjct: 521 LTVMA 525
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.8 bits (145), Expect = 1e-11 Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 2/81 (2%) Query: 497 STALVVDDDPAFRMTMRRLLADRADRVLEAGDGHEALAALHADPPDVVFLDLMLPGLDGG 556 +T LV DDD A R + + L+ V + + A D+V D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 557 EVMSTMGADPALRDIPVVIVT 577 +++ + A D+PV++++ Sbjct: 64 DLLPRIKK--ARPDLPVLVMS 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 6e-19 Identities = 45/163 (27%), Positives = 69/163 (42%), Gaps = 6/163 (3%) Query: 5 RASVLVVDDSVSKRYVLGSWLRRAGYEVFEASSGEEALREVRDHVPDLVVLDVHLPDLSG 64 A++LV DD + R VL L RAGY+V S+ R + DLVV DV +PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 65 IEVCRRIKRDRESAGVPVLHVSAIAVDAGDRSIGLDEGADAYLVDPIEPREFLSTVGALL 124 ++ RIK+ R +PVL +SA ++GA YL P + E + +G L Sbjct: 63 FDLLPRIKKARP--DLPVLVMSAQN-TFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 125 RQSRRYAEEHRIALTLQRSLL---PATLPDLAGLRVAARYHAS 164 + +R + L+ A L + + Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLT 162
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 35.0 bits (80), Expect = 0.001 Identities = 26/140 (18%), Positives = 36/140 (25%), Gaps = 10/140 (7%) Query: 27 ESSTPSRPS---PPAPAGGSSRGGSAGVPTRADGTPRGVPAERAATPPRSAAPPRSATPK 83 E P++P APA A P E PP+ A K Sbjct: 42 ELPAPAQPISVTMVAPADLEPP--QAVQPPPEPVVEPEPEPEPIPEPPKEAPV---VIEK 96 Query: 84 PGPATPKAGPTPKTGPTAPRAGRAGGATPKAGPAGDAGPAGDAGPAGDAGPAGDAGPAGD 143 P P K R + + P + A + A A A Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASG 156 Query: 144 AGPQGTARPA--ARARPAGV 161 +P ARA+ + Sbjct: 157 PRALSRNQPQYPARAQALRI 176
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 53.7 bits (129), Expect = 1e-10 Identities = 18/102 (17%), Positives = 34/102 (33%), Gaps = 4/102 (3%) Query: 36 VASSGEQALSPALRGRLDLILLDFFLPDMSGLDVCRALRARGSALDIIAVSLVRDLAMVQ 95 + S+ G DL++ D +PD + D+ ++ L ++ +S Sbjct: 32 ITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAI 91 Query: 96 AAMSYGVIQYVVKPF----TAIAFRRCLERYSAFRRQIAAGA 133 A G Y+ KPF R L ++ + Sbjct: 92 KASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDS 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.2 bits (177), Expect = 6e-17 Identities = 32/131 (24%), Positives = 59/131 (45%), Gaps = 4/131 (3%) Query: 2 RVLLVEDDHGVGGAIKDVLDARGHPVEWVTRGADAL--LRHRNADLLLLDLGLPDISGLE 59 +L+ +DD + + L G+ V + A + + DL++ D+ +PD + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 60 VLRRLR-RLAATPVLVLTAMGTHERDIVRGLRLGADDYLIKPVRMDELLARMEAILRRTE 118 +L R++ PVLV++A T ++ GA DYL KP + EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFM-TAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 119 RGGATPVGRVQ 129 R + Q Sbjct: 124 RRPSKLEDDSQ 134
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 36.1 bits (83), Expect = 8e-05 Identities = 43/207 (20%), Positives = 85/207 (41%), Gaps = 12/207 (5%) Query: 41 GIDYVDYVVPGVLLVCAGFGAA--TTAVTVTSDLTTGVIDRFRSMDVSGAALISGHVVAS 98 G+ Y ++ G++ A A T + + ++ G + + Sbjct: 62 GVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWA 121 Query: 99 VVRNLVSTALVVAVALAIGFRPSAGVGGWLVAGGVLALFVLALSWLSATIGIVAGSPEAA 158 + ++ A + VA A+G+ + L A V+AL LA + L +V + Sbjct: 122 ATKAALAGAGIGVVAAALGYTQWLSL---LYALPVIALTGLAFASLGM---VVTALAPSY 175 Query: 159 NGFTFFVSFLAYP----SSAFVPVDTMPSWLRGFARDQPVNTVVETTRAALTGEPVGSIA 214 + F F+ + + P S A PVD +P + AR P++ ++ R + G PV + Sbjct: 176 DYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVC 235 Query: 215 WHAVAWSLGIIAVSVVASSVLFNRRIR 241 H A + I+ +++++L R +R Sbjct: 236 QHVGALCIYIVIPFFLSTALLRRRLLR 262
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 67.2 bits (164), Expect = 8e-16 Identities = 47/212 (22%), Positives = 82/212 (38%), Gaps = 18/212 (8%) Query: 17 LSLERIVAAAVDVAQADGIGALSMSRVAAELGAATMSLYRYVAAKDELLLLMVDAAMG-- 74 L+ E ++ AA+++ GI L+ ++A +LG +LY +V K LL + + Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 75 -SPPGPREPDDGWRAGLSRWAQGARAAYDRHPWALRVPISTPPLGPNMVAWMDDGLRCLA 133 P + W++ L A R A R+ +V + T P ++ LR + Sbjct: 64 HDYSLP-AAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDT-VETQLRFMT 121 Query: 134 HTPLTEQQKLSSVLLLSGFVRNEATLSADLKAASGGEKMMPGYGALLSRLIDPAVFPSLQ 193 + + L ++ +S F + AA P D + P L+ Sbjct: 122 ENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAP----------DENLPPLLR 171 Query: 194 RAIDSGSLDDDDDMDGEFDFGLARLLDGIAVL 225 A+ + D DD + F GL L+ G V Sbjct: 172 EALQ---IMDSDDGEQAFLHGLESLIRGFEVQ 200
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.0 bits (72), Expect = 0.007 Identities = 35/120 (29%), Positives = 48/120 (40%), Gaps = 12/120 (10%) Query: 102 SQSLRAVLDREGRLALAETAAIGTCVLAAL----VATH--AAGVVHRDVTPANILLG-TD 154 S +LR + D + + A GT A V H AGVVH D+ P N++ Sbjct: 223 SDTLRTLADSWKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRAS 282 Query: 155 GSARLTDFGAALRTTDQRITVGALGVPGFVAPEVLTGR-SPQPVADVFALGVTLFTAAEG 213 G + D G R+ +Q F APE+ G +DVF + TL EG Sbjct: 283 GEPVVIDLGLHSRSGEQPKGF----TESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>cloacin#Cloacin signature. Length = 551 Score = 31.2 bits (70), Expect = 0.020 Identities = 18/60 (30%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 851 GPSPAGPDDQATAVCEQP-GSSGGSGPGEGLDGYGGAGGSGGSGGLG---GSGEETVSAP 906 G D + P G GSG G G GG G+ G G G V+AP Sbjct: 28 GVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAP 87
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.6 bits (144), Expect = 5e-13 Identities = 32/216 (14%), Positives = 67/216 (31%), Gaps = 8/216 (3%) Query: 12 AAPGRPVRWSGEDAVLDAAKASLLAVGVRRTTLTEVARRAGVSRMTLYRRWPDLRSLVGD 71 A + +LD A GV T+L E+A+ AGV+R +Y + D L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 72 VMTREWTRVVTAAAARPTAPDRSGGDLDDLVDHIIATVEAFRTNPVYLRIIETDPELL-- 129 + + + G L L + +I +E+ T ++E Sbjct: 62 IWELSESNI--GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 130 ---LPYLTERRGATQQMIIDLLAGQLDAAARSGTVRP-VEPAALAVMVLLVVQSFVLSAD 185 + + + + D + L + + + A+++ + + + Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 186 ALAGPVPAATLAAELRRLLRGYLAPDAKHAPPASAE 221 A + +L PA+ E Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 61.2 bits (148), Expect = 2e-13 Identities = 46/173 (26%), Positives = 72/173 (41%) Query: 1 MIGPGTSFGVELVRRYGREGFALGVVSRSADTLTRVRDALAAEGLTVAGAVADVTDSAAL 60 + G G + R +G + V + + L +V +L AE ADV DSAA+ Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAI 72 Query: 61 AGAVERVSAEIGGLTVLVYNAKLSIRGAALTVAAETMNQTLAVNVTGALAAVQVAAGLLD 120 R+ E+G + +LV A + G +++ E T +VN TG A + + + Sbjct: 73 DEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMM 132 Query: 121 DRAAATILLTTAGPRTEPVAGRFALAVGKAGLAALAEALRPTLAARGIRLRTV 173 DR + +I+ + P P A A KA + L LA IR V Sbjct: 133 DRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.025 Identities = 13/58 (22%), Positives = 16/58 (27%), Gaps = 8/58 (13%) Query: 147 GGVAAAGQPLAGFDPTRGSA------ARLPAARLPAARESAARESAAR--LPAVRAPA 196 G G L A + L ARL R S LP ++ P Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.0 bits (119), Expect = 5e-10 Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 2/105 (1%) Query: 2 RRLLDAGLTLLIDRGTSEAVRVADIVAAAGLSNRAFYRYFASKDDLVAAIVDDGMRRAES 61 + +LD L L +G + + +I AAG++ A Y +F K DL + I + Sbjct: 14 QHILDVALRLFSQQGV-SSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 62 YLRHLM-DRETSPERRLRAMIAGFLRQATDPVIGAATRAVLAQSE 105 P LR ++ L ++ Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKC 117
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 25.5 bits (56), Expect = 0.032 Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 35 AETEHERLERLEQALDQCWDLLRRRRARRDAGQDPQGAE 73 + E +E+L AL++ + LR + + +A AE Sbjct: 35 TDVSTE-IEKLTAALEKSKEELRAIKDQTEASMGADKAE 72
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.5 bits (237), Expect = 9e-26 Identities = 77/255 (30%), Positives = 113/255 (44%), Gaps = 15/255 (5%) Query: 2 LVTGGSDGLGAALVRTLAAEGARVAFCGRDEARLRSVAEAAGDAGRAGGAGGEVLPVVAD 61 +TG + G+G A+ RTLA++GA +A + +L V + R E P AD Sbjct: 12 FITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA----EAFP--AD 65 Query: 62 VREPADLERFVAAATERWDAVDALVNNAGASSAGPFERQTDEVWQGDLDLKLHAAVRASR 121 VR+ A ++ A +D LVN AG G +DE W+ + ASR Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 LVLPHLRRAGGGSIVNSLSITARTPGAGSMPTSVTRAAGLALTKALSKEFGPDNVRVNAI 181 V ++ GSIV S A P + ++AA + TK L E N+R N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 182 LIGMVESG-QW----DRAAAAQGIGIDELYARMGRDSNIPLGRVGRAQEFADLVAFLLSA 236 G E+ QW D A Q I + G IPL ++ + + AD V FL+S Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTG----IPLKKLAKPSDIADAVLFLVSG 241 Query: 237 RAAYITGTAVNLDGG 251 +A +IT + +DGG Sbjct: 242 QAGHITMHNLCVDGG 256
>PF06580#Sensor histidine kinase Length = 349 Score = 38.3 bits (89), Expect = 5e-05 Identities = 18/102 (17%), Positives = 40/102 (39%), Gaps = 24/102 (23%) Query: 374 LIDNAV----AAMDHRGTLTVRTFADHDFGVVEIGDSGPGIDPAIRDRIFEPFFTTKAVG 429 L++N + A + G + ++ D+ +E+ ++G K Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA--------------LKNTK 308 Query: 430 EGTGLGL-DISWRIVVKKHHGD---LRVTSTPGDTRFQVRLP 467 E TG GL ++ R+ + +G ++++ G V +P Sbjct: 309 ESTGTGLQNVRERL--QMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 1e-16 Identities = 24/117 (20%), Positives = 43/117 (36%), Gaps = 9/117 (7%) Query: 23 RPAILTVDDDPSVSRAVARDLRRQYGERYRIVRAESGSQALDALREMKLRGDRVAVLLAD 82 IL DDD ++ + + L R Y + + + + +++ D Sbjct: 3 GATILVADDDAAIRTVLNQALSR---AGYDVRITSNAATLWRWIAA-----GDGDLVVTD 54 Query: 83 FRMPAMNGIEFLEQAMDLYPTARRVLLTAYADTTAAIDAINIVDLDHYLLKPWDPPQ 139 MP N + L + P ++++A AI A D YL KP+D + Sbjct: 55 VVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYD-YLPKPFDLTE 110
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.8 bits (69), Expect = 0.012 Identities = 10/37 (27%), Positives = 19/37 (51%) Query: 270 AASGAVAGLVAITPAAGYVTPVGSIVIGLLAGGVCAL 306 AA V+ +VA+ + T +G I ++ G +C+ Sbjct: 471 AADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCSY 507
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 29.4 bits (65), Expect = 0.005 Identities = 17/40 (42%), Positives = 23/40 (57%) Query: 8 PPDLTGRGGEFLDFWRERHLCSLTTVRADGSAHVVAVGAT 47 P L GGE L+ +R+ C T VRAD +A+ + VG T Sbjct: 215 PRYLQACGGEKLNRFRDIQCCRQTAVRADLNANYIQVGNT 254
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 69.6 bits (170), Expect = 2e-16 Identities = 39/153 (25%), Positives = 62/153 (40%), Gaps = 4/153 (2%) Query: 29 RLTREAIVDAAVAMADAEGLEAVSIRRVAAALDARPMSLYSHFDRKDDLL-ALMNDQVAA 87 RL RE+++DAA+ + + G++ ++ R++A L +LY H K LL AL + +A Sbjct: 3 RLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILAR 62 Query: 88 EVIVPEPLPT-DWRDALRAIAHRTRDSSLRHPWVLQTLACHPRLGPNGLRHAEQSAAAVA 146 P W+ LR A R + LR+ + R E + Sbjct: 63 HHDYSLPAAGESWQSFLRNNAMSFRRALLRYR-DGAKVHLGTRPDEKQYDTVETQLRFMT 121 Query: 147 ALPLPPRRRAAMLRAVDTYTLGHVTAELRERQG 179 R + AV +TLG V E +E Sbjct: 122 ENGFSLRDGLYAISAVSHFTLGAVL-EQQEHTA 153
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 110 bits (277), Expect = 3e-28 Identities = 77/399 (19%), Positives = 172/399 (43%), Gaps = 16/399 (4%) Query: 34 LDATIVSVALDTLARSFDVGVSTIQWVSTGYLLALAVVIPLTGWSVERFGGKRMWLASLT 93 L+ +++V+L +A F+ ++ WV+T ++L ++ + G ++ G KR+ L + Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 94 LFLVGSVLCGIAWSAGS-LIAFRVVQGAGGGLLLPLMQTILAQAAGPARLGRLMATVAVP 152 + GSV+ + S S LI R +QGAG L+ ++A+ G+ + Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 153 ALLTPVLGPVVGGVLIDDLGWRWIFLVNVPVCAVAIALAWRLMPEMRVAQRHPFDGVGFA 212 + +GP +GG++ + W ++ L+ + + + + +L+ + V + FD G Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKK-EVRIKGHFDIKGII 205 Query: 213 LLSPGLAVAIYGLSEAGRRGDFADPRALVPMIVGLAMIAVFAWHALRTRIVPLIDLRLFR 272 L+S G+ + F ++ +IV + +F H + P +D L + Sbjct: 206 LMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVT-DPFVDPGLGK 254 Query: 273 FASFCGSAGMMFLFGLSLYGAMLLLPLYEQQVRGRSAIEAG-LLLAPQGLGMMLAMIVVG 331 F + ++ G + ++P + V S E G +++ P + +++ + G Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 332 RLVDRTSPRLLVLIGLGLSLLGSVAYTQVGVDTSEVLLGGSLVLRGMGLAAASIPVMSAA 391 LVDR P ++ IG+ + + + + ++T+ + +V GL+ + + Sbjct: 315 ILVDRRGPLYVLNIGVTFLSVSFLTASFL-LETTSWFMTIIIVFVLGGLSFTKTVISTIV 373 Query: 392 YHGLRPADIPRATSAVRIFQQIGGSLGTAVLAVVLAHQL 430 L+ + S + + G A++ +L+ L Sbjct: 374 SSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.005 Identities = 15/75 (20%), Positives = 26/75 (34%), Gaps = 8/75 (10%) Query: 289 RASAATIELR-RPDGASLLLRVSDDGVGGADPRR---GTGLAGLTGRLDAI---DGTLVV 341 I L+ D ++ L V + G + GTGL + RL + + + + Sbjct: 275 LPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKL 334 Query: 342 VSPPGGPTLVTVALP 356 G V +P Sbjct: 335 SEKQGKVN-AMVLIP 348
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 64.0 bits (156), Expect = 1e-13 Identities = 48/194 (24%), Positives = 73/194 (37%), Gaps = 21/194 (10%) Query: 1 MRVLVTGATGKVGGAVVRAALEAGHQVRVL---------VRDPARVPGLPRP-VEVVVGD 50 M+ LVTGA G +G V + LEAGHQV + AR+ L +P + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 51 VTDPATLPA--AVAGTEIVFN---AMGVPEQWLPDAAEFDRVNVAGSDNVARAAARAGVR 105 + D + A E VF + V A D N+ G N+ ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD-SNLTGFLNILEGCRHNKIQ 119 Query: 106 RLVHTSTIDVFDAPPGGRFDETALAAAPKGTPYERSKQRAERAVLAAAG--GMQVVIVNP 163 L++ S+ V+ F P + Y +K+ E + G+ + Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPV-SLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 164 ATVYGFPPYGPTSM 177 TVYG P+G M Sbjct: 179 FTVYG--PWGRPDM 190
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 59.4 bits (144), Expect = 1e-11 Identities = 55/249 (22%), Positives = 88/249 (35%), Gaps = 51/249 (20%) Query: 1 MRILVTGATGFLGSRVVPRALAQGHEVVGL---------ARSATAAAALRRQGAAAVAGD 51 M+ LVTGA GF+G V R L GH+VVG+ + L + G D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LDDPAGLSAAFTAADCAVLLNLA-------SLGFGHADA---------IVSATRAAGIRR 95 L D G++ F + + SL HA A I+ R I+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 96 AVFLSTTGI--------FTALDPPSKRV------RIAAE---HTI-ETSGLEWTIIRPTM 137 ++ S++ + F+ D V + A E HT GL T +R Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 138 IYGGSDDRNMA-----RLLALVRRVPVLPLPGGGRRLHQPVHVDDLAATVLRALSADAAV 192 +YG +MA + + + + V G+ ++DD+A ++R Sbjct: 181 VYGPWGRPDMALFKFTKAMLEGKSIDVY---NYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 193 GRGYDVAGP 201 + V Sbjct: 238 DTQWTVETG 246
>PF05844#YopD protein Length = 295 Score = 35.8 bits (82), Expect = 3e-04 Identities = 26/57 (45%), Positives = 27/57 (47%), Gaps = 7/57 (12%) Query: 426 PDEPARPGGAGRSTGAPDAPDAPDAP-VPAQRAAAP---APHRAPTGPRPATAPGPE 478 P EP PG AGRS G P A A + P VPA RA AP R P A G E Sbjct: 16 PSEPIAPGAAGRSVGTPQA--AAELPQVPAARADRVELNAP-RQVLDPVRMEAAGSE 69
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 48.2 bits (115), Expect = 1e-08 Identities = 49/257 (19%), Positives = 82/257 (31%), Gaps = 46/257 (17%) Query: 8 GATGFIGAACAAALAAAGHEVLP------------RPARRLAVDGEALTGVP-ERAYRPH 54 GA GFIG + L AGH+V+ + AR + + A R Sbjct: 7 GAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLADREG 66 Query: 55 LPGLAAELDGVGAVVNAAGVAVSAARLSPE----LVGGNAAWPRLLADACERAGVPRLVH 110 + L A V + A R S E N + + C + L++ Sbjct: 67 MTDLFAS-GHFERVFISP--HRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHLLY 123 Query: 111 VSTAAVQGRVDRLDESLRYA-------PVNPYARSKTLGEQLLRDAAAAGRVAVTLYRPP 163 S+++V G L+ + ++ PV+ YA +K E + + + T R Sbjct: 124 ASSSSVYG----LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 164 SVHGSGRRMTTAFAAFCRRW----PLVTCGDGGQPVPVALIGNVGAAVAAILAA------ 213 +V+G R A F + + G I ++ A+ + Sbjct: 180 TVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADT 239 Query: 214 -----DGAPLVVSHPYE 225 G P PY Sbjct: 240 QWTVETGTPAASIAPYR 256
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.8 bits (215), Expect = 8e-21 Identities = 68/337 (20%), Positives = 115/337 (34%), Gaps = 35/337 (10%) Query: 38 RALITGITGQDGLYLGELLTAKGYEVFGLVRGQSNP------KVAVVERLV-PGVVLLEG 90 + L+TG G G ++ + L G++V G+ N K A +E L PG + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGI--DNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 91 DLTDLPSLIGAVEISQPDEVYNLGAISFVGLSWKQAELTGETTGMGVLRVLEALRIAGGN 150 DL D + + V+ V S + ++ G L +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK-- 117 Query: 151 DMSRVRFYQASSSEMFGKVRETPQRETTPF-HPRSPYGVAKTFGHYLTVNYRESYGAFAC 209 + + + ASSS ++G R+ P HP S Y K + Y YG Sbjct: 118 -IQHLLY--ASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG-LPA 173 Query: 210 SGL-LFNHESPRRGIEFVTRKITRAVARISLGLQDSLTLGNLESRRDWGFAGDYVEAMWR 268 +GL F P + K T+A+ L + + +RD+ + D EA+ R Sbjct: 174 TGLRFFTVYGPWGRPDMALFKFTKAM----LEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 269 MLQQETPDDYVVATGVTHSIRELLDAAFGRVGIGDWSGL------------VKQDPRF-- 314 + D + +G L ++ Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP 289 Query: 315 FRPAEVDVLVGDPSKAREVLGWTPRVGFEELIAMMVD 351 +P +V D EV+G+TP ++ + V+ Sbjct: 290 LQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVN 326
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.9 bits (64), Expect = 0.046 Identities = 25/100 (25%), Positives = 41/100 (41%), Gaps = 6/100 (6%) Query: 260 AAGPLSVSPLIAQSAPCNGGSTTANLAGINLPGILNTGV-ITASGAAVLGNPTLAATKIT 318 AA L+V+P+ A + P N +T + IN V +T S +A+ Sbjct: 12 AAALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSISAIAAVAKSDTMPAI 71 Query: 319 LANINILSGLITAS--SITSQANASKGNGQPAVIDATGTQ 356 + L+G I+AS + AN K +G + D+ Sbjct: 72 PGS---LTGSISASYNGKSYTANLPKDSGNATITDSNNNT 108
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 27.0 bits (60), Expect = 0.048 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 13/60 (21%) Query: 26 GAQPVEVRRAAQLAEVDGLVLPGGESTTIGRLLQVFELLEPLRAAVVAGLPVFGSCAGMI 85 GA VE RRA + ES +VF + EP+ AA+ AGLPV + M+ Sbjct: 117 GATQVE-RRAIR------------ESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMV 163
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.3 bits (65), Expect = 0.012 Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 163 RAAAPAAPVSRPAPATPARRSPRPAAPARRPA 194 A APV PAPATP+ + A +++ + Sbjct: 1017 IARVDEAPVPPPAPATPSETTETVAENSKQES 1048
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.026 Identities = 13/49 (26%), Positives = 22/49 (44%), Gaps = 5/49 (10%) Query: 34 RKVREQLSIMLEGAQARGRPP----DHVL-LSGPPGLGKTSLAMIIAEE 77 R ++ +L G AR P D+ + L G G+GK++L + Sbjct: 571 RYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 64.9 bits (158), Expect = 2e-13 Identities = 30/184 (16%), Positives = 68/184 (36%), Gaps = 9/184 (4%) Query: 432 AFERSQAESISPTLGRDSLRGGLLAGAIGLVLVVAY-SFLYYRALGIVVVASLAVSGAII 490 A + + ES+ P + + + + + V+++ Y + + V +L + Sbjct: 134 ALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLT 193 Query: 491 YASVVLLGAAIGFTLTLAGIAGLIVSIGVTADSFVVYFERIKDEVQA--GRTVRASADRA 548 +L L +A L+ G + + VV F+R+++ + +R + + Sbjct: 194 VGLFAVLQ----LKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLS 249 Query: 549 WPAA-RRTMLSADTVSFLAAAVLYILSIGSVRGFAFTLGLSTLSDVLIMFIFTRPMVALL 607 RT+++ T LA + I +RGF F + + + +V + Sbjct: 250 VNETLSRTVMTGMTT-LLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFI 308 Query: 608 VRRR 611 R Sbjct: 309 GLDR 312
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 260 bits (666), Expect = 2e-86 Identities = 83/339 (24%), Positives = 154/339 (45%), Gaps = 32/339 (9%) Query: 13 HVDFVGRRRVWYAVSGVILVICAVSMIFRGFTLGIEFSGGAVFQLPS-HGGTVEQVEQTL 71 + DF + + + V+++ + + G GI+F GG + S V L Sbjct: 13 NFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAAL 72 Query: 72 SSVGIDPA------DGVVQQLETSKQFRVQTPTLTD------AQTDKLTDALAKRFSVTD 119 + + D ++ + R+Q AQ +L + + + D Sbjct: 73 EPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVD 132 Query: 120 PD-RDIAVSTVGSSWGSTITSKAIQGLVVFLVLVMIYLSVRFEWKMAVAAMAALIHDLVV 178 P + + +VG + A+ L+ V++M Y+ VRFEW+ A+ A+ AL+HD+++ Sbjct: 133 PALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLL 192 Query: 179 TMGVYSLVGFEVTPSTVIAVLTILGFSLYDTVVVFDRVRENTAGMATSHRRTYAEATNDA 238 T+G+++++ + +TV A+LTI G+S+ DTVVVFDR+REN + N + Sbjct: 193 TVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKY---KTMPLRDVMNLS 249 Query: 239 LNETLVRSLNTSLIALIPVASLLFVGAGLLGAGTLKDLALAQFVGIASGTYSSLFFATPL 298 +NETL R++ T + L+ + +L G ++ A G+ +GTYSS++ A + Sbjct: 250 VNETLSRTVMTGMTTLLALVPMLI-----WGGDVIRGFVFAMVWGVFTGTYSSVYVAKNI 304 Query: 299 LVDLKRGEPAVQALDARVARERGKRARAVASTAAGPGAP 337 ++ + +E+ + S A GAP Sbjct: 305 VLFIGL----------DRNKEKKDPSDKFFSNGAQDGAP 333
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.3 bits (63), Expect = 0.044 Identities = 14/62 (22%), Positives = 23/62 (37%) Query: 140 NDSVAEYLGASRQNLASLTAAAPAADLYAVASLTAPVTPDEMLGVLGAYRAVQVFFTAGV 199 S L +R + AA PA + VA + G++G+ A+ + Sbjct: 99 GHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI 158 Query: 200 GG 201 GG Sbjct: 159 GG 160
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 27.2 bits (60), Expect = 0.041 Identities = 11/33 (33%), Positives = 13/33 (39%), Gaps = 11/33 (33%) Query: 154 PSPRDGRSWRQYMGLLVRAMQYDLRENAEEFRR 186 P G SW+ + LR NA FRR Sbjct: 67 SLPAAGESWQSF-----------LRNNAMSFRR 88
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 39.9 bits (93), Expect = 4e-06 Identities = 42/130 (32%), Positives = 60/130 (46%), Gaps = 2/130 (1%) Query: 89 FGALRAAGALDYYLTLPIPPAAVVLGTAASYATFAAPGTVITAVLGALLYNLPITGLWLL 148 FG + + L + +VLG A AT AA V+ A L L Sbjct: 91 FGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLYA 150 Query: 149 LPVVVLSGVCLAGLGAVVGLLAPRPELATIAGQLGMSIVLFLG--VIPADRLPEIGRVAR 206 LPV+ L+G+ A LG VV LAP + L ++ +LFL V P D+LP + + A Sbjct: 151 LPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAA 210 Query: 207 DVLPSSYAVD 216 LP S+++D Sbjct: 211 RFLPLSHSID 220
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.003 Identities = 10/60 (16%), Positives = 19/60 (31%), Gaps = 6/60 (10%) Query: 14 DSPAAEPSPTSPLPARSRWPLSLGLRPDLIAGLICAAAMAVAGFPLGLLWAAVAPHLDVA 73 D+P E LPA L L P A + + + + + +++ Sbjct: 30 DTPVREKDENEFLPAH----LELIETPV-SRRPRLVAYFIMGFLVIAFILSVLGQ-VEIV 83
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.1 bits (62), Expect = 0.013 Identities = 13/42 (30%), Positives = 15/42 (35%) Query: 93 IAKDRPAEGRPWDAPGASPPDPPPVADPPPAADPPPADPPPA 134 + P +P PG PP PP PA PP A Sbjct: 567 VGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSA 608
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.002 Identities = 17/107 (15%), Positives = 38/107 (35%), Gaps = 3/107 (2%) Query: 72 IELVRTRSARDSQRLESGAVTNSRELENLQAELASLARRQ---GVLEDDALEKMEAVEGL 128 ++L + D+ + +S + E Q S+ + L D+ + + E + Sbjct: 125 LKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 129 EGRLAALDQRRADLQAEIDAAITARDKAYAEIDTESARMRQDRQALA 175 + + ++ + Q + DK AE T AR+ + Sbjct: 185 LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSR 231
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 33.7 bits (77), Expect = 0.002 Identities = 28/127 (22%), Positives = 46/127 (36%), Gaps = 25/127 (19%) Query: 73 GKSTLVNRILGRRAAV-----------------VEDVPGVTRDRIAYDAVWNGRRFTLVD 115 GK+TL +L A+ +E G+T W + ++D Sbjct: 15 GKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIID 74 Query: 116 TGGWEPDASGLAAQVSEQASAALDTADAVLFIVDVTTGATDADEAVARVLHRSGLPVILV 175 T P A+V ++ + LD A ++ D G + L + G+P I Sbjct: 75 T----PGHMDFLAEV-YRSLSVLDGAILLISAKD---GVQAQTRILFHALRKMGIPTIFF 126 Query: 176 ANKVDDN 182 NK+D N Sbjct: 127 INKIDQN 133
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 53.6 bits (129), Expect = 2e-10 Identities = 27/83 (32%), Positives = 37/83 (44%), Gaps = 11/83 (13%) Query: 11 MRVFVTGASGHIGSAVVPELLRAGHQVVGL---------ARSDSSAEALTAAGADVCRGD 61 M+ VTGA+G IG V LL AGHQVVG+ + + E L G + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 62 LDDLDGLR--VAAAAADGVIHLA 82 L D +G+ A+ + V Sbjct: 61 LADREGMTDLFASGHFERVFISP 83
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.8 bits (69), Expect = 0.016 Identities = 28/105 (26%), Positives = 39/105 (37%), Gaps = 19/105 (18%) Query: 169 LPAASKALHRAGARPAPSPSKLRRALAVELGAPDVQPGPARLAASDTAAQVVHAYLAEHT 228 L A +KAL A+ A +KLR A + PD +PG + A Q Sbjct: 437 LEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQ---------- 486 Query: 229 AALLDRDPAVRVNAPEAVHDMRVAARRLRSTVQTFRPLFDAERAA 273 + N +A M+ R+L ST +T P F A Sbjct: 487 -------AGTKPNQNKA--PMKETKRQLPSTGETANPFFTAAALT 522
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 3e-10 Identities = 24/179 (13%), Positives = 51/179 (28%), Gaps = 7/179 (3%) Query: 8 SVTVSEILAEAQLSTRAFYRHFTSKDQLLLAMFEEESERATAQLTQRLASTP-DPYTAVG 66 S ++ EI A ++ A Y HF K L ++E + A P DP + + Sbjct: 31 STSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLR 90 Query: 67 AWIRFHIQLAFEPRRHRRTLVMQTLELHRV---AGYAEALARHQELNRAPLVRALEAGAA 123 + ++ R R + + + V A +A + + + L+ Sbjct: 91 EILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIE 150 Query: 124 AGIFRHTRPTTDSIMIQDIVNNVLLRRRDGIETNDGETVRATIHEFLSRAIGVQHRPDP 182 A + + I+ + + + + P Sbjct: 151 AKML---PADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCP 206
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 55.3 bits (133), Expect = 9e-12 Identities = 34/146 (23%), Positives = 59/146 (40%), Gaps = 8/146 (5%) Query: 24 LHEAEIVASALSIIERDGVEGLTMRRLSQSLGVSLGATYKHVATKDDLL-RLVTAELYTR 82 L+ ++ +AL ++ G++GLT R+L+Q LG+ Y HV K LL L L Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 83 V-LAADTPDADWRPRLRSFLLRMHEVVGTCRGLAAHLAAHADDPVTARLYYPLHAA---L 138 + W+ LR+ + + R A H + Y + + Sbjct: 64 HDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGA---KVHLGTRPDEKQYDTVETQLRFM 120 Query: 139 TQAGFTPAGADRVLRTLFFYTSGALL 164 T+ GF+ + + +T GA+L Sbjct: 121 TENGFSLRDGLYAISAVSHFTLGAVL 146
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.8 bits (77), Expect = 0.001 Identities = 18/84 (21%), Positives = 25/84 (29%), Gaps = 1/84 (1%) Query: 25 PAAPAAGSPPRAPVDLPPAAPPPPPPSRAVRTLLTVGATLVLGVGAGVAPALAAEPATSA 84 P P APV + P P P + V+ + + +P PA Sbjct: 79 EPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPT 138 Query: 85 -AVPAAAVPAAVARPGCDAAALQR 107 + AA V AL R Sbjct: 139 SSTATAATSKPVTSVASGPRALSR 162
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 127 bits (319), Expect = 3e-37 Identities = 89/271 (32%), Positives = 136/271 (50%), Gaps = 17/271 (6%) Query: 12 LEGKVALITGGARGQGRAHAVTCAREGADVVIVDITEQLSTVAYKMAVQADVDETVAQVE 71 +EGK+A ITG A+G G A A T A +GA + VD + +++ V+ ++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPE------------KLEKVVSSLK 53 Query: 72 ALGRRALAIEADVRSQSELDDAVAQGIAEFGKIDILIANAGIWTQAPFWKLTEDQWDQMI 131 A R A A ADVR + +D+ A+ E G IDIL+ AG+ L++++W+ Sbjct: 54 AEARHAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATF 113 Query: 132 GVNLTGVWKSAKAVTPHMIERRSGSIVITSSVNGLEPGQNYAHYVSAKHGVIGLMKNIAL 191 VN TGV+ ++++V+ +M++RRSGSIV S P + A Y S+K + K + L Sbjct: 114 SVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173 Query: 192 ELARYGIRCNSINPGAILTPMTDHQAAWDMFAGHPGGTEADMIEGGYHYGALKGTTFLDP 251 ELA Y IRCN ++PG+ T M W ++A G + + P Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQ-----WSLWADENGAEQVIKGSLETFKTGIPLKKLAKP 228 Query: 252 QAIADTALYLNSDLAANVTGVTIPVDAGHLL 282 IAD L+L S A ++T + VD G L Sbjct: 229 SDIADAVLFLVSGQAGHITMHNLCVDGGATL 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.9 bits (129), Expect = 3e-11 Identities = 32/182 (17%), Positives = 60/182 (32%), Gaps = 13/182 (7%) Query: 1 MIDNTDPRAVRTRERLVAAFHEAVRVADPSEMSVSALARAAGINRTSFYTHFASPEDLAI 60 M T A TR+ ++ S S+ +A+AAG+ R + Y HF DL Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 YALGEVFDVVQGADIALRTRHGVSAAEASRRALRDIVR--FVDSHR-----VVYARLLGP 113 + ++ + + R L ++ + R +++ + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 114 GAAPRLVQAIADAFTE---HTVETLGRMDNRP---PGVDITLTARFLAGGVLGVIGCWLA 167 G + QA + E +TL + A + G + G++ WL Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 168 DP 169 P Sbjct: 181 AP 182
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.0 bits (184), Expect = 8e-19 Identities = 42/211 (19%), Positives = 75/211 (35%), Gaps = 13/211 (6%) Query: 10 RPSRRGLPAKREAIMDAALGLFVRQGYAATTLDEIATATPVSRQTVYNHFGDKETLFRAV 69 R +++ R+ I+D AL LF +QG ++T+L EIA A V+R +Y HF DK LF + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 VDAHLAATLDVLREASSGLHG-PLPDAETCLHDLARRLIAIAGNPRAAS-LRRLLQAEGE 127 + + ++ E + G PL L + + + + GE Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 128 RQPELLALWRDQVAAPVFAEVTGLLARLAHGGALHLDDPVRAAGQFIALVWGTGWQLTSL 187 ++ + + + + L L D R A + + Sbjct: 123 M--AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY---------I 171 Query: 188 GTVAGAASADPDERELDVALRSCVRLFVRGY 218 + P +L R V + + Y Sbjct: 172 SGLMENWLFAPQSFDLKKEARDYVAILLEMY 202
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.1 bits (125), Expect = 3e-11 Identities = 20/94 (21%), Positives = 37/94 (39%), Gaps = 7/94 (7%) Query: 14 RVHPVGDGLEALAYLRDSAQPRPDLIILDLNMPRMDGRETLAAIKK-DPDLCTIPVVMLT 72 V + ++ DL++ D+ MP + + L IKK PD +PV++++ Sbjct: 29 DVRITSNAATLWRWIAAGD---GDLVVTDVVMPDENAFDLLPRIKKARPD---LPVLVMS 82 Query: 73 TSQAPEDVRASYQLHANAYVCKPQTFDEFIHAVQ 106 + + A Y+ KP E I + Sbjct: 83 AQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>cloacin#Cloacin signature. Length = 551 Score = 38.2 bits (88), Expect = 5e-05 Identities = 24/58 (41%), Positives = 30/58 (51%), Gaps = 1/58 (1%) Query: 202 SPGGDDPHTDSHTGEHTNPSTRTTGSGSGSGSGSGSGSGSGSGSGSG-SGSGSGSGGD 258 P G + G + G GSGSG G GSG G+G G+G SG GSG+GG+ Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 37.0 bits (85), Expect = 1e-04 Identities = 28/83 (33%), Positives = 36/83 (43%), Gaps = 5/83 (6%) Query: 224 TTGSGSGS-----GSGSGSGSGSGSGSGSGSGSGSGSGGDDAGNDGRKKPSPDPADIRRL 278 + GSG S G GSGSG G GSG G+G G+G+ G +G G P Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFP 93 Query: 279 TLTDTPTGTTLISGELDAEGAAL 301 L+ G +S A AA+ Sbjct: 94 ALSTPGAGGLAVSISAGALSAAI 116 Score = 36.2 bits (83), Expect = 2e-04 Identities = 19/56 (33%), Positives = 26/56 (46%) Query: 215 GEHTNPSTRTTGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGGDDAGNDGRKKPSP 270 G + + G GSGSG G GSG G+G G+G+ GG G + +P Sbjct: 32 GASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAP 87 Score = 36.2 bits (83), Expect = 2e-04 Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 8/60 (13%) Query: 213 HTGEHT---NPSTRTTGSGSGSGSGSGSGSGS-----GSGSGSGSGSGSGSGGDDAGNDG 264 +TG H+ N + TG G G G+ GSG S G GSGSG G GSG + G +G Sbjct: 10 NTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Score = 33.5 bits (76), Expect = 0.002 Identities = 20/55 (36%), Positives = 26/55 (47%), Gaps = 5/55 (9%) Query: 217 HTNPSTRTTGSGSGSGSGSGSGSGSGSGSGSGS-----GSGSGSGGDDAGNDGRK 266 H + T+G+ +G +G G G G+ GSG S G GSGSG G G Sbjct: 9 HNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63
>ENTEROTOXINA#Heat-labile enterotoxin A chain signature. Length = 258 Score = 28.1 bits (62), Expect = 0.009 Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 9/58 (15%) Query: 5 ELARATGTTPRALRYYEEQG------LLRPSR-TGAGYRVYDDGAVTTVGTIR--HLL 53 E+ R+ G PR Y ++G L +R T G+ YDDG V+T ++R HL Sbjct: 33 EIKRSGGLMPRGHNEYFDRGTQMNINLYDHARGTQTGFVRYDDGYVSTSLSLRSAHLA 90
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 41.9 bits (98), Expect = 5e-06 Identities = 22/88 (25%), Positives = 35/88 (39%), Gaps = 14/88 (15%) Query: 204 AVTALLGGAVVAFAVEAVVLQVADAHAGAGAGAGAHLPEMLLAGAGVAVLASLLVLVVAS 263 V+ +L +F +L ADA A AG L +L G + ++ A Sbjct: 244 TVSGILSAISASF-----ILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQ 298 Query: 264 VRDTLLPVGLAVTAVALAAAVASELSSA 291 GL+ +A A A +AS ++ A Sbjct: 299 --------GLSTSA-AAAGLIASAVTLA 317
>cloacin#Cloacin signature. Length = 551 Score = 35.1 bits (80), Expect = 0.002 Identities = 28/81 (34%), Positives = 39/81 (48%), Gaps = 4/81 (4%) Query: 888 GVGGAGFGTAGVSLPNSQPLGTGDSSLLGQDGTTGLGDLAGAGGLAGAGGLGGADGSMSL 947 GVGG +G S N+ P G G S + G +G G GG +GG G G++S Sbjct: 28 GVGGGASDGSGWSSENN-PWGGGSGSGIHWGGGSGHG---NGGGNGNSGGGSGTGGNLSA 83 Query: 948 KGSPMSGGMPFMPMGGMGGLG 968 +P++ G P + G GGL Sbjct: 84 VAAPVAFGFPALSTPGAGGLA 104
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 40.3 bits (94), Expect = 2e-04 Identities = 22/122 (18%), Positives = 35/122 (28%), Gaps = 1/122 (0%) Query: 4059 SAPAVAPAVAQRTPSLSPPPPVGLPSILEVPEEDLAPQ-EGLPPQDPPPRQPPSSSPRRA 4117 APA +V P+ PP P V E + P+ PP++ P + Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 103 Query: 4118 ADVDAITVAAPVVVTEPAVEPGSGLAAPSTRSVAPSRPVAEERDLLEMVGARWPVGSARR 4177 V P +P + + + S A P +R Sbjct: 104 KPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRN 163 Query: 4178 EP 4179 +P Sbjct: 164 QP 165 Score = 34.2 bits (78), Expect = 0.014 Identities = 16/53 (30%), Positives = 17/53 (32%) Query: 1178 STAATPAVIPTVAPRDPEPQADGQSPPTVESTPPPAEVPAPVDPAPPADSAPP 1230 A P + VAP D EP Q PP P P P P P Sbjct: 44 PAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Score = 33.8 bits (77), Expect = 0.020 Identities = 19/134 (14%), Positives = 28/134 (20%), Gaps = 9/134 (6%) Query: 2598 LGITTVIETDEAQRVDKPTH----WVAKPTTPAPHA--TLPRRAATDPIVPTPSTVP--- 2648 G+ + VA P A P P P P Sbjct: 30 AGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKE 89 Query: 2649 APPTAPTPPRRAATDPTAPTAPTAPTDLTAPTDLTAPTASTVPTSTAPGPVGSTTSAAAD 2708 AP P + P P P + + P +T + + Sbjct: 90 APVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKP 149 Query: 2709 APPPAAPRDVLVPP 2722 A+ L Sbjct: 150 VTSVASGPRALSRN 163 Score = 33.0 bits (75), Expect = 0.034 Identities = 16/90 (17%), Positives = 24/90 (26%) Query: 727 QPDPLLSNITAPAPAPAPPASPLAPALSTPPALSTPPALSTPQVPPAVGPNPPAGPQHTA 786 P + P P P P P A P V P P + Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESR 124 Query: 787 SPPSLDSRPAASPETSSFSDGASSDAPAPA 816 ++ A P +S+ + S + A Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVTSVA 154
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.5 bits (84), Expect = 5e-04 Identities = 21/109 (19%), Positives = 32/109 (29%), Gaps = 6/109 (5%) Query: 540 HDASDRAAADWSPADPGAVD--RDADAASRWAPQPADRPHSPAGGDPTRMPDPSPPSRTG 597 H + A PA P +V AD A QP P +P +P+P + Sbjct: 38 HQVIELPA----PAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVV 93 Query: 598 NPAGSPPPAAPPSAAPPSAAPEKDPGDPIAVQREHSRPDPGSVGGGPSA 646 P P P P++D + + +A Sbjct: 94 IEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTA 142 Score = 32.3 bits (73), Expect = 0.009 Identities = 18/86 (20%), Positives = 25/86 (29%), Gaps = 4/86 (4%) Query: 570 PQPADRPHSPAG-GDPTRMPDPSPPSRTGNPAGSPPPAAPPSAAPPSAAPEKDPGDPIAV 628 PAD A P + +P P P PP AP P P+ P V Sbjct: 55 VAPADLEPPQAVQPPPEPVVEPEPEP---EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKV 111 Query: 629 QREHSRPDPGSVGGGPSADPPDGSNP 654 ++ P + + P Sbjct: 112 EQPKRDVKPVESRPASPFENTAPARP 137
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 73.3 bits (180), Expect = 6e-16 Identities = 88/363 (24%), Positives = 139/363 (38%), Gaps = 65/363 (17%) Query: 5 LGIDLGTTFTAVAIGWPDRREMVSLGNRSIVA-PTVVYAGRDGHLLTGDAADRRALREPD 63 L IDLGT T + + + + + L S+VA G A + R P Sbjct: 13 LSIDLGTANTLIYV----KGQGIVLNEPSVVAIRQDRAGSPKSVAAVGHDAKQMLGRTPG 68 Query: 64 --RAAREFKRRLGDPTPVLLGDAPYSPAALLAAVLHDAVGSAIRLQGGPPQQIVLTRPAV 121 A R K + + D + +L + ++ P ++++ P Sbjct: 69 NIAAIRPMKDGV-------IADF-FVTEKMLQHFIKQVHSNSF---MRPSPRVLVCVPVG 117 Query: 122 WGPYRMEQFDEVPRLAGLVDVTLVTEPVAAATYYATGRRLSDGDVIAVYDLGGGTFDAAV 181 E + AG +V L+ EP+AAA G +S+ V D+GGGT + AV Sbjct: 118 ATQVERRAIRESAQGAGAREVFLIEEPMAAAI--GAGLPVSEATGSMVVDIGGGTTEVAV 175 Query: 182 LRM----EAGQARILGNPEGIEWLGGADFDEAILHHVDRE---LDGAVTAADPRDRDSAV 234 + + + RI GG FDEAI+++V R L G TA Sbjct: 176 ISLNGVVYSSSVRI----------GGDRFDEAIINYVRRNYGSLIGEATA---------- 215 Query: 235 ALSRLRQECVLAKEALSADEDTVIPV----LLPGIRQDVKLGRAQFEEMIRPAIESTVEA 290 R++ E A DE I V L G+ + L + E ++ + V A Sbjct: 216 --ERIKHE---IGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSA 270 Query: 291 LHRALSSAEVRPDDLSA------VLLAGGSSRIPLVARMIEAATGRPTVVDAHPKHVVAL 344 + AL E P +L++ ++L GG + + + R++ TG P VV P VA Sbjct: 271 VMVAL---EQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVAR 327 Query: 345 GAA 347 G Sbjct: 328 GGG 330
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 4e-14 Identities = 26/114 (22%), Positives = 44/114 (38%), Gaps = 2/114 (1%) Query: 4 SVLLVDDQPLLRLGFRMVLSSQPDLTVAGEAGDGAEAIRLTAELAPDVVLMDVRMPGMDG 63 ++L+ DD +R LS + A R A D+V+ DV MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 64 IEATRQIIAAGGTARILILTTFDLDQYAYAALRSGASGFLLKDVRPADLLSAIR 117 + +I A +L+++ + A A GA +L K +L+ I Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.0 bits (109), Expect = 4e-08 Identities = 19/87 (21%), Positives = 38/87 (43%), Gaps = 4/87 (4%) Query: 2 RVVIGEDEGLLREALTGALEQWDVEVAASAGTPTEIVRLVDEVRPDVVILDIHMPPDFTD 61 +++ +D+ +R L AL + +V + R + D+V+ D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPD---E 60 Query: 62 EGLRAAERIRAAHPDIGLLLLSHYAEV 88 RI+ A PD+ +L++S Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTF 87
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 2e-04 Identities = 13/70 (18%), Positives = 27/70 (38%), Gaps = 9/70 (12%) Query: 528 IRVEPHPGELLLRITDDG---CGGARPGRGHGLRNLHDRVAAL---DGTVTLHSPAGGGT 581 ++ G + L + + G + G GL+N+ +R+ L + + L G Sbjct: 283 LKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 582 RLLVRLPLPG 591 + +PG Sbjct: 343 ---AMVLIPG 349
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.9 bits (77), Expect = 0.006 Identities = 31/159 (19%), Positives = 59/159 (37%), Gaps = 7/159 (4%) Query: 1904 ITGGLRGVGLETAAWLASRGAGRLVLNGRSAPTSQVEQRLARLAAAGTDVQVVLGDAAET 1963 ITG +G+G A LAS+GA ++ +V L A D ++ Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA---DVRDS 69 Query: 1964 QTADRLVAAAVADGLALRGVVHSAMVLADAAITGITGEQVDRVWRPKAEAAWRLHEATA- 2022 D + A + + +V+ A VL I ++ E+ + + + + + + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 2023 ---DRQLDWFVLYSSMSSLLGNPGQGAYAAANSWLDSFA 2058 DR+ V S + + AYA++ + F Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFT 168
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 3e-15 Identities = 20/116 (17%), Positives = 41/116 (35%), Gaps = 2/116 (1%) Query: 6 IRTLIVEDDPLLADAHRLYVERVPGFTVCGVARSGTEALRVALADRPDLLLLDFYLPGMS 65 L+ +DD + + R G+ + + R A DL++ D +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GLEVCRALRAHGATADIIAVTSARDLATVRAAVSYGVVQYLVKPFSFAAFRQRLER 121 ++ ++ ++ +++ T A G YL KPF + R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.0 bits (184), Expect = 7e-19 Identities = 33/176 (18%), Positives = 62/176 (35%), Gaps = 4/176 (2%) Query: 7 LGRPVNADAERTRRRILLAAMTHVAEVGYSRATMKSIAEQADLTSAAIYRYFPSKADLVL 66 + R +A+ TR+ IL A+ ++ G S ++ IA+ A +T AIY +F K+DL Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 67 QALDDVFADVVGRLEAAAFSVEG-LRARLVALLEEALACMADHPSMTRFEASLLFESTHS 125 + + +++ G + L +L L + + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 126 PEFAAAVGYRRHTEETLYRR---LVVEAVDTGELPVGTSVEAMVDLLTSVSWGLTH 178 E A +R+ Y R + ++ LP ++ GL Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME 176
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 30.6 bits (68), Expect = 0.018 Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 2/110 (1%) Query: 208 VGVDYDGPPPGREPGGWHRTYTELAAKAHVWNPALGARLSALAVAAARRRSTPRRVRAIG 267 +G++Y PP GG + + + + A + A A+ +A+AV A + V AIG Sbjct: 47 LGLEYPVRPPVPGAGGLNASAKGIHSIA-IGATAEAAKGAAVAVGAGSIATGVNSV-AIG 104 Query: 268 GVVLTTGGYGFNRELVARHAPDWAGLAALGTAGDTGAALGLAAAVDAATS 317 + G + D + A + DTG A+G + DA S Sbjct: 105 PLSKALGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNS 154
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 25.2 bits (55), Expect = 0.026 Identities = 7/37 (18%), Positives = 14/37 (37%) Query: 14 MTEGVIGEWLADDGAAVEAGQPLYVLATDKTETEIEA 50 + ++ E + +G +V G L L E + Sbjct: 102 IENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 70.5 bits (172), Expect = 2e-16 Identities = 69/279 (24%), Positives = 109/279 (39%), Gaps = 53/279 (18%) Query: 15 AFVTGASRGIGKAIALSLAEAGYDLAVSARTVRPGEIRDNALTVHHSDERPLPGSLAETA 74 AF+TGA++GIG+A+A +LA G +A D P ++ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAA-------------------VDYNPEKLEKVVSS 51 Query: 75 AEIEARGREALVVPCDLTDRESVEAAARRILDTWGGVDVIVHNGRYIGPGIMDVFLDTPL 134 + EAR EA P D+ D +++ RI G +D++V+ + PG++ Sbjct: 52 LKAEARHAEAF--PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIH---SLSD 106 Query: 135 DAYEKMFEAHCIAPIILTRALLPAMLARGGGAVVTITSGAAWLVPPAPAGQGGWGLAYAV 194 + +E F + +R++ M+ R G++VT+ S A VP AYA Sbjct: 107 EEWEATFSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAG-VPRTSMA------AYAS 159 Query: 195 GKASGNPLVGILHTEYAGRGLRVFNVEPGFVATE-RNEISVRDYGRELVGA--------- 244 KA+ L E A +R V PG T+ + + + G E V Sbjct: 160 SKAAAVMFTKCLGLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTG 219 Query: 245 ------APPSAIGATVRWLLDSPDADSLLGTTIEAQDLC 277 A PS I V +L+ S I +LC Sbjct: 220 IPLKKLAKPSDIADAVLFLV------SGQAGHITMHNLC 252
>PF05844#YopD protein Length = 295 Score = 25.0 bits (54), Expect = 0.046 Identities = 13/41 (31%), Positives = 16/41 (39%), Gaps = 4/41 (9%) Query: 16 DPPGPAAAGRSTVMPHQPSRTFRAPAQRPARYGRKGALPRP 56 +P P AAGRS P + Q PA + L P Sbjct: 18 EPIAPGAAGRSVGTPQAAAEL----PQVPAARADRVELNAP 54
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 33.2 bits (75), Expect = 9e-04 Identities = 18/61 (29%), Positives = 24/61 (39%), Gaps = 7/61 (11%) Query: 67 PTPSISSPTSPTPSPTPTRSPSPAPSPSGDPS-------GGDSSPTVRTTSPRPFVTTDG 119 P P +S +P +P P +P P+P DP D P R SP +G Sbjct: 327 PLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNG 386 Query: 120 R 120 R Sbjct: 387 R 387 Score = 32.4 bits (73), Expect = 0.001 Identities = 18/70 (25%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 67 PTPSISSPTSPTPSPTPTRSPSPAPSPSGDPSGGDSSPTVRTTSPRPFVTTDGRLASPSR 126 P P ++ ++ P+ P SPA +P+ +P+ ++ T P P + D + + Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370 Query: 127 PSDGTALDNP 136 P GT D+P Sbjct: 371 P--GTRPDSP 378
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.1 bits (184), Expect = 5e-18 Identities = 50/194 (25%), Positives = 90/194 (46%), Gaps = 3/194 (1%) Query: 5 QGQVAVVTGAASGIGYGLAEALAARGVHVVLSDVQTDAVERAAATLAAAGATTLAVAADV 64 +G++A +TGAA GIG +A LA++G H+ D + +E+ ++L A A ADV Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 65 GDADQVGALAAATIDRFGRVDLVCNNAGVVSRPAPMWEQGLASWRWLIDVALLGVVHGVH 124 D+ + + A G +D++ N AGV+ RP + W V GV + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 125 HFVPHLIRQGGGHVLNTASVGGLMPLPTLTPYNAVKHAVIGLTETLDLELRAVAPTLGAS 184 +++ + G ++ S +P ++ Y + K A + T+ L LEL + + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN--IRCN 183 Query: 185 VLCPGPVATALSET 198 ++ PG T + + Sbjct: 184 IVSPGSTETDMQWS 197
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 4e-12 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%) Query: 3 GEHTRRDLLLAAERLFAAGGIDGPSMREISKAAGQLNTSALQYHFGDRQAVLAAIIDRHH 62 + TR+ +L A RLF+ G+ S+ EI+KAAG + A+ +HF D+ + + I + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAG-VTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 63 RDIETHRLGLLDALELDGEPPVG 85 +I L D + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLR 90
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (280), Expect = 6e-32 Identities = 76/253 (30%), Positives = 119/253 (47%), Gaps = 10/253 (3%) Query: 8 LSGRTAVVTGASRGIGAACARALDAAGARVAVVARGGAGLAAVADGL---ANKPVTISAD 64 + G+ A +TGA++GIG A AR L + GA +A V L V L A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 65 LTVEDDVRRVADQALDELGDVDILVNNAGLGWHQPPEAITAKPLDLQLNLNLRNVILLTS 124 + + + + E+G +DILVN AG+ +++ + + ++N V + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 125 WLAPSLLRRR-GCVVTMSSAAAYGGDVEQAVYAATKGGLNTLTQNLATAWGDRGVRVNAV 183 ++ ++ RR G +VT+ S A A YA++K T+ L + +R N V Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 184 APGFVDTDI-WQPLIAALGEEGYQRFRRATAA---GIPLRRWASADEIATVVLFLCSDAA 239 +PG +TD+ W G E Q + + GIPL++ A +IA VLFL S A Sbjct: 186 SPGSTETDMQWSLWADENGAE--QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 240 SYLTGQTLVVDGG 252 ++T L VDGG Sbjct: 244 GHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.3 bits (138), Expect = 2e-12 Identities = 39/196 (19%), Positives = 75/196 (38%), Gaps = 12/196 (6%) Query: 21 SQEYRDRLENIVRVAADVFQAHGYEAGSLDDVAAAMGLRKASLYYYVKRKSDLLRLVFER 80 QE ++ ++I+ VA +F G + SL ++A A G+ + ++Y++ K KSDL ++E Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 81 AITVALTEVETLA--HLADPRERLAALIRHQ-ALLVTRDPALFAVFFDQRAGLEHADLAD 137 + + DP L ++ H VT + + ++A Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 138 VGHKE---HLYLRQFILA-VEAAMAAGAIPPG-DPRLVA---NAVIGMTSWSYKWFDARR 189 V + L I ++ + A +P R A I ++ + Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSF 185 Query: 190 DSPEAFADTCVALVLR 205 D + A VA++L Sbjct: 186 DLKKE-ARDYVAILLE 200
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 41.9 bits (98), Expect = 4e-06 Identities = 17/102 (16%), Positives = 23/102 (22%), Gaps = 4/102 (3%) Query: 705 ADPPAPVDPPTAADPPTPADPPTPADVATPADVATP---ADVATSTTVPAASTKPAATVP 761 + PAP P + P A P V P + A P Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPK-P 99 Query: 762 SSAPTPPAASPTPVAAATPVASGSAAGAHVSGSAGATPAVAG 803 P P S + +A A P + Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141 Score = 38.4 bits (89), Expect = 6e-05 Identities = 26/110 (23%), Positives = 40/110 (36%), Gaps = 2/110 (1%) Query: 693 LALQRRFRPPAPADPPAPVDPPTAADPPTPADPPTPADVATPADVATPADVATSTTVPAA 752 A+Q P +P P + P + P P P V + P Sbjct: 64 QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK-KVEQPKRDVKPVE 122 Query: 753 STKPAATVPSSAPTPPAASPTPVAAATPVASGSAAGAHVSGSAGATPAVA 802 S PA+ ++AP P +S A + PV S ++ +S + PA A Sbjct: 123 SR-PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARA 171 Score = 36.9 bits (85), Expect = 2e-04 Identities = 24/154 (15%), Positives = 40/154 (25%), Gaps = 6/154 (3%) Query: 654 LNRVFGLPDEFVLLLGGLGLVVTAVLNPEGVAGKVRTDLLALQRRFRPPAPADPPAPVDP 713 L R F P + + G +V + ++ + PA +PP V P Sbjct: 10 LPRRFPWPTLLSVCIHGA-VVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQP 68 Query: 714 PTAADPPTPADPPTPADVATPADVATPADVATSTTVPAASTKPAATVPSSAPTPPAASPT 773 P P + P + P KP V Sbjct: 69 PPEPVVE----PEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESR 124 Query: 774 PVAAATPVASGSAAGA-HVSGSAGATPAVAGDAR 806 P + A + + ++ +VA R Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGPR 158
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 32.6 bits (73), Expect = 0.002 Identities = 20/58 (34%), Positives = 28/58 (48%), Gaps = 5/58 (8%) Query: 20 VNGLDLRVDEG-----RLVGLIGPNGAGKTSFIDGISGFTRTQGAIHFRGKRVDREPA 72 ++ LD RVD+G L L P G GK +F G+ G+ +Q G RV+ A Sbjct: 375 LDKLDTRVDKGLASSAALNSLFQPYGVGKVNFTAGVGGYRSSQALAIGSGYRVNENVA 432
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 25.5 bits (56), Expect = 0.045 Identities = 13/70 (18%), Positives = 28/70 (40%), Gaps = 6/70 (8%) Query: 13 VRNGSIVTVVWDRGLLDGDPPTVDLVEVEADLLAES-RRDPLQRRRDGDATTTAT----- 66 +++G +V V G++ +P ++ E A ++ + +TT Sbjct: 213 IQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVEL 272 Query: 67 AATVGDPESA 76 AA +G P+ Sbjct: 273 AANIGTPKDV 282
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 3e-08 Identities = 20/154 (12%), Positives = 52/154 (33%), Gaps = 7/154 (4%) Query: 7 RGLRVDAARNYERIIAAADQAFEDVG-RAVTLEEVARRAGVGVATVYRRFRNRDQLLRTV 65 R + +A + I+ A + F G + +L E+A+ AGV +Y F+++ L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 66 FDHLVSTEIVPRLTRETDDPWHDLVGALEATVAALAGRQVILALARETDAFHVEGVHRYL 125 ++ + + G + + + + + E +E + Sbjct: 63 WE-----LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKC 117 Query: 126 ESMERLLGRARDAGVVRPELERRDLSAVVVMALA 159 E + + + + E + + + Sbjct: 118 EFVGEMAVVQQAQRNLCLES-YDRIEQTLKHCIE 150
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 48.1 bits (114), Expect = 3e-08 Identities = 21/76 (27%), Positives = 26/76 (34%), Gaps = 1/76 (1%) Query: 307 PDAPRSPTRIMAATYQPPPPAPQPPQPPPPARTPPPQTPAPPRTPPPQTPPGPQTPPGPQ 366 P P S T + A PP A QPP P P P+ P P P+ P P+ Sbjct: 41 PAQPISVTMVTPAD-LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK 99 Query: 367 ASPGPRTPPPRPAQVP 382 P + V Sbjct: 100 PKPVKKVQEQPKRDVK 115 Score = 36.1 bits (83), Expect = 3e-04 Identities = 30/150 (20%), Positives = 43/150 (28%), Gaps = 21/150 (14%) Query: 275 PPSVISLVAEHAAAIGAHLPPTRPDPSVWWETPDAPRSPTRIMAATYQPPPPAPQP-PQP 333 P IS+ A + P V P+ P +PP AP +P Sbjct: 41 PAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIP--------EPPKEAPVVIEKP 92 Query: 334 PPPARTPPPQTPAPPRTPPPQTPPGPQTPPGPQASPGPRT--------PPPRP----AQV 381 P + P P P P P + P +P A Sbjct: 93 KPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASG 152 Query: 382 PRHPAVADVVFPGRRRRLLVVGSLLVGVGV 411 PR + +P R + L + G + V V Sbjct: 153 PRALSRNQPQYPARAQALRIEGQVKVKFDV 182
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.0 bits (119), Expect = 7e-10 Identities = 25/160 (15%), Positives = 53/160 (33%), Gaps = 9/160 (5%) Query: 12 TRRRGDGLLAAIFDAVFDQLRTVGYANLTMDRVAAAAGTSKTVLYRRWAAKEDMIADAVR 71 T++ I D G ++ ++ +A AAG ++ +Y + K D+ ++ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 72 YRLPNPGDVP--LTGDVRADVHALLRCV-------QASFSATRGTALQLVSAEAGCGRPA 122 N G++ D ++LR + + R + G A Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 123 VRQTIIDHVVEPCVRLIGEVLRRAAERGEIRPESASELVA 162 V Q ++ I + L+ E + + + A Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA 164
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.4 bits (60), Expect = 0.029 Identities = 18/63 (28%), Positives = 25/63 (39%), Gaps = 6/63 (9%) Query: 6 VDPTGDAPTGRDPDRPSPPDPHPAADPDATPPMDPDSG--PDAEPGAP----EPTGDDRK 59 V P + P+ P+P DPD P +PD+ P P +P P G RK Sbjct: 331 VSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRK 390 Query: 60 STR 62 + Sbjct: 391 ERK 393
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.031 Identities = 15/68 (22%), Positives = 26/68 (38%), Gaps = 5/68 (7%) Query: 2 STKLHGLVPRRLAPIVAGRLAE-----EPVVLLQGPRSVGKSTLLRGLAADLGAELIDLD 56 + LV + + R+ E + V+L+G +GKSTL+ L D Sbjct: 569 RLRYLQLVGKYILMGHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFD 628 Query: 57 DLASRDAA 64 +D+ Sbjct: 629 IGTGKDSY 636
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (280), Expect = 6e-32 Identities = 77/261 (29%), Positives = 118/261 (45%), Gaps = 18/261 (6%) Query: 1 MTGAARGQGRADALRLAEEGADVIVVDVCAPLPSVDYLSATPQDLAETVSLIEKTGRRVV 60 +TGAA+G G A A LA +GA + VD P+ L + VS ++ R Sbjct: 13 ITGAAQGIGEAVARTLASQGAHIAAVD------------YNPEKLEKVVSSLKAEARHAE 60 Query: 61 SGIVDVRDLAALRSIVDDGAAQLGRLDVVVANAGICIPRAWDKVTPQIYQDTISTNVTGV 120 + DVRD AA+ I ++G +D++V AG+ P ++ + ++ T S N TGV Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 121 WNTVMVGAPHLVRAGGGSIIIISSAAGLKVQPFMVPYTTSKFAVRGMAKAFAAELSQHHI 180 +N + +++ GSI+ + S + M Y +SK A K EL++++I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 181 RVNSVHPTGVNTPMGTGSMRQRIDEA--IAGYDRLGPMFMNLLPVDG-TEPEDVADTVLF 237 R N V P T M I G F +P+ +P D+AD VLF Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGS---LETFKTGIPLKKLAKPSDIADAVLF 237 Query: 238 LASDESRFITAHEIAPDAGNT 258 L S ++ IT H + D G T Sbjct: 238 LVSGQAGHITMHNLCVDGGAT 258
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.6 bits (149), Expect = 8e-14 Identities = 31/135 (22%), Positives = 47/135 (34%), Gaps = 6/135 (4%) Query: 24 RERILAAAEVLFAEHRFDRTSTARIAAAAGVPHGLIFYHFKTKMDLLLAVVQRDRVTTLG 83 R+ IL A LF++ TS IA AAGV G I++HFK K DL + + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 84 ELDLPPSDLPPSEGTDPRRAVAELWRHLTVVLGRPSPVHRIVLQELAVHEEIRRRAMEST 143 + P DP + E+ H+ ++ E+ H+ M Sbjct: 73 LELEYQAKFPG----DPLSVLREILIHVLESTVTEERRRLLM--EIIFHKCEFVGEMAVV 126 Query: 144 DAAAAVIAGRLARIF 158 A + Sbjct: 127 QQAQRNLCLESYDRI 141
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.009 Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 34 LVGRSGGGKTTLLRTLAGLDPVAEGSVEVPALRSVVFQ 71 L G G GK+TL+ TL GLD ++ ++ + Q Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQ 638
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.7 bits (152), Expect = 2e-13 Identities = 30/201 (14%), Positives = 70/201 (34%), Gaps = 13/201 (6%) Query: 288 RRVTRRSEPTIRRILAAANQAFERGGLAGTSVDDITAEAGVAHGTFYQYWEDRYAVFATL 347 R+ + ++ T + IL A + F + G++ TS+ +I AGV G Y +++D+ +F+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 348 AHQAAVDICTHLDDLLRAEDEDDILAWIDRWLDVLRQ------RGPTLHVWTTEVLPTAP 401 + +I + D + + + VL R + + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 402 LQRLSR-------QLRGYLDAVTARLMARWAPGRSLDPSAAAIVLWVLLGEFPYHAWQRH 454 + + + + ++ + L AAI++ + + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 455 PVLDRDDVHRSLALLLVGGLL 475 D R +L+ L Sbjct: 183 QSFDLKKEARDYVAILLEMYL 203 Score = 55.8 bits (134), Expect = 4e-11 Identities = 32/166 (19%), Positives = 58/166 (34%), Gaps = 12/166 (7%) Query: 32 PEGERACAEIVAAARDLFAQRGYHGTSILAITEATGRSDTAFYQYFQSKIELFALFYEQL 91 E + I+ A LF+Q+G TS+ I +A G + A Y +F+ K +LF+ +E Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 92 GRDLVRHFRRQRVVEPGPAGLAEFRTWLEGL--DDVLRRHSPVFAAWPLVADDALMPEDP 149 ++ + + L+ R L + V + + + Sbjct: 67 ESNIGELE-LEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 150 SEQYLRELAEEMRPRL-ALAGAG--------PVDTRVLAIAIISLM 186 +Q R L E R+ + TR AI + + Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.2 bits (130), Expect = 4e-11 Identities = 22/101 (21%), Positives = 42/101 (41%), Gaps = 2/101 (1%) Query: 41 RRHQRDALDELEQILDAALRVAVRVAPAEPRVSDIVAEAGTSNQTFYRYFAGKGELLHAV 100 R+ +++A + + ILD ALR+ + + + +I AG + Y +F K +L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 101 MERGVLRVRSYLTHQMAKEASPADQVAAWVQGLLTQLTLPE 141 E + AK P D ++ + L+ L Sbjct: 63 WELSESNIGELELEYQAKF--PGDPLSVLREILIHVLESTV 101
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 73.9 bits (181), Expect = 9e-18 Identities = 59/253 (23%), Positives = 110/253 (43%), Gaps = 19/253 (7%) Query: 13 RVVLVTGGSRGLGREIAFGAARCGADVVVASRDLDSCTATAAEIEAETGRKALPYAVHVG 72 ++ +TG ++G+G +A A GA + + + + ++AE R A + V Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVR 67 Query: 73 RWDELPGLVDAAYERFGKVDALINNAG---MSPLYDTLGDVNEKLFDAVVNLNLKGPFRL 129 + + G +D L+N AG ++ ++++ ++A ++N G F Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHS----LSDEEWEATFSVNSTGVFNA 123 Query: 130 SVLVGERMVAAGRGCIVNVSSTGSIRPTPAILPYAAAKAGLNALTEGLALALGPH-VRVN 188 S V + M+ G IV V S + P ++ YA++KA T+ L L L + +R N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 189 TLMSGPFYTDVSRH-W-DLDAVAEAAKSHA--------LQRAGDPPEIVGSALYLISDAS 238 + G TD+ W D + + K L++ P +I + L+L+S + Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 239 SYTSGATLRVDGG 251 + + L VDGG Sbjct: 244 GHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 4e-14 Identities = 21/75 (28%), Positives = 40/75 (53%) Query: 34 AGRLGWRAARTRNAILDASKKLFLERGYAGTRINNITDACGISRAGFYTYFRDKREIFDT 93 A + A TR ILD + +LF ++G + T + I A G++R Y +F+DK ++F Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 94 LGQATFRELLQVIAE 108 + + + + ++ E Sbjct: 62 IWELSESNIGELELE 76
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.5 bits (128), Expect = 5e-11 Identities = 30/154 (19%), Positives = 59/154 (38%), Gaps = 10/154 (6%) Query: 9 PDRAERERRAIIRAAHRLIGREGRAATPLEDILRGAGVNRRTFYRHFPSKDALVLTMQRE 68 A+ R+ I+ A RL ++G ++T L +I + AGV R Y HF K L + Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 69 AAAGVRDSLRAAVREAGDARAAAVAWIEELLAIGWDERASRDGRTFM-------TPEVGL 121 + + + + + ++ + E+L + + + R + VG Sbjct: 66 SESNIGE---LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 122 VVGIADALEDIYAEHRGILAEVLAAGRTDGSLPA 155 + + A ++ E + + L LPA Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPA 156
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 6e-10 Identities = 26/130 (20%), Positives = 52/130 (40%), Gaps = 6/130 (4%) Query: 14 ARTAREVVEAKEQAMLAASRAVVELFVERGTNDFTIRELAAHAGVSERSFYRYFPRKEDV 73 AR ++ + Q +L + LF ++G + ++ E+A AGV+ + Y +F K D+ Sbjct: 2 ARKTKQEAQETRQHILDVAL---RLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDL 58 Query: 74 VRPFLTAGAARI---ATELTERPPGEPLQTSLAVIWAASWAATHVEQLRQLYRVLRTSEG 130 + I E + PG+PL ++ + E+ R L ++ Sbjct: 59 FSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 131 FRAQWFQIMA 140 F + + Sbjct: 119 FVGEMAVVQQ 128
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.4 bits (73), Expect = 0.009 Identities = 18/58 (31%), Positives = 24/58 (41%) Query: 149 PGASGAPGVSGAPGVSGAPGVSGAPGVSGAPGVSGVPGADGSFEADGSFEADGAAGRR 206 PG++ AP P VS A + P + PG P D D + + DG G R Sbjct: 317 PGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTR 374
>cloacin#Cloacin signature. Length = 551 Score = 34.3 bits (78), Expect = 7e-04 Identities = 24/71 (33%), Positives = 31/71 (43%), Gaps = 4/71 (5%) Query: 169 GGRRRADDGADTPPGGT---GESGIGRRDDRSDGNSGGDDDDGGSGGSG-GPDGGGDDGG 224 GG R + G G +G+G SDG+ +++ GGSG G GG G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGH 62 Query: 225 DGGGGGGGDGG 235 GGG G GG Sbjct: 63 GNGGGNGNSGG 73 Score = 33.9 bits (77), Expect = 0.001 Identities = 17/50 (34%), Positives = 21/50 (42%) Query: 183 GGTGESGIGRRDDRSDGNSGGDDDDGGSGGSGGPDGGGDDGGDGGGGGGG 232 G + SG ++ G SG GG G G G G+ GG G GG Sbjct: 32 GASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 32.0 bits (72), Expect = 0.004 Identities = 17/53 (32%), Positives = 22/53 (41%) Query: 182 PGGTGESGIGRRDDRSDGNSGGDDDDGGSGGSGGPDGGGDDGGDGGGGGGGDG 234 GG G G + + G GGSG +GGG+ GG G GG+ Sbjct: 29 VGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 28.5 bits (63), Expect = 0.048 Identities = 15/37 (40%), Positives = 19/37 (51%) Query: 179 DTPPGGTGESGIGRRDDRSDGNSGGDDDDGGSGGSGG 215 + P GG SGI GN GG+ + GG G+GG Sbjct: 43 NNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGG 79
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 52.7 bits (126), Expect = 1e-10 Identities = 30/155 (19%), Positives = 55/155 (35%), Gaps = 8/155 (5%) Query: 27 RALRRRRIHDALSAAAITLFLERGFDDVSVAEIAAAAEVSKPTLFAYFPTKEDL---VLH 83 + + A+ LF ++G S+ EIA AA V++ ++ +F K DL + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 84 RILDHRGEAARVVRARAPG--VAPLTAVAAHLLAGLDRREPVSGLNDHPEVLAFHALVFE 141 + GE +A+ PG ++ L + H+L E L + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 142 TPSLLGRVAQYAGQDEHDLADALSEAAPQAGDLAA 176 R + +D + + +A L A Sbjct: 125 VVQQAQRNLC---LESYDRIEQTLKHCIEAKMLPA 156
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 3e-08 Identities = 30/171 (17%), Positives = 52/171 (30%), Gaps = 24/171 (14%) Query: 1 MAGPRPGLRRDTQETRDRLLAAVGELLAESGPT-FGLPELARRGGVATATAYRHFETIHD 59 MA +++ QETR +L L ++ G + L E+A+ GV Y HF Sbjct: 1 MARKT---KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHF----K 53 Query: 60 AHREFLLQLTGRLTDRLRSVPPTWTPRRRFDAACERWAEQAADWGPAAVHIRSWRGFLER 119 + ++ + + + E + V R +E Sbjct: 54 DKSDLFSEIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEI 112 Query: 120 VHLGDEPTGAL--------------YAALEPIVRDLIEHGEL-PDQDVEYA 155 + E G + Y +E ++ IE L D A Sbjct: 113 IFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRA 163
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 31.2 bits (70), Expect = 0.005 Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 29 FDRGQFVTVVGTNGAGKSSLIQTISGAARPTRGRVHLDGRDVTRLPDHRRAGWIARVFDD 88 F+ G+ G+N + IQ + R+ +G+D L + R A A D Sbjct: 493 FENGRVRVDTGSNWSEVLPQIQETTA-------RIIFNGKD-LNLVERRIA---AVNPSD 541 Query: 89 PRAGTAPELSIEDNLALAMARGRARGL 115 P T P++++++ L +A G Sbjct: 542 PLETTKPDMTLKEALKIAFGFNEPNGN 568
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 27.8 bits (61), Expect = 0.011 Identities = 18/64 (28%), Positives = 26/64 (40%), Gaps = 9/64 (14%) Query: 6 PGQLPSISGAAGHGDLVVTSGVICPDLLRPGLTPATTPDVRQQIDGALAALRDVLRAAGS 65 P + P SG G G+ T+ P P+ R ++ L LR+ L A + Sbjct: 163 PRERPHTSGHHGAGEARATA---------PSTVSPYGPEARAELSSRLTTLRNTLAPATN 213 Query: 66 DLRY 69 D RY Sbjct: 214 DPRY 217
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.5 bits (69), Expect = 0.006 Identities = 11/29 (37%), Positives = 15/29 (51%) Query: 1 MQIVVIGGTGLIGAKLVQRLTGHGHSAVA 29 M+ +V G G IG + +RL GH V Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVG 29
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 4e-21 Identities = 34/129 (26%), Positives = 58/129 (44%), Gaps = 1/129 (0%) Query: 2 RVLVVEDEVRTAAVLRRGLVEEGYAVDVVGDGIDAVWRATEIAYDAIVLDLMLPGIDGFE 61 +LV +D+ VL + L GY V + + D +V D+++P + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VCRRLRAGHRWAPVLMLTARVDVDDRIRGLDAGADDYLPKPFSFGELTARL-RALVRRGA 120 + R++ PVL+++A+ I+ + GA DYLPKPF EL + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 VHRPVVLRA 129 + + Sbjct: 125 RPSKLEDDS 133
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 112 bits (281), Expect = 4e-29 Identities = 91/414 (21%), Positives = 174/414 (42%), Gaps = 19/414 (4%) Query: 1 MRTGPALVALAGAALLAVLDGTVVAVALDPLAHAFSAPLTTVVWVTIAYLLAAATALPLL 60 +R L+ L + +VL+ V+ V+L +A+ F+ P + WV A++L + + Sbjct: 10 LRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVY 69 Query: 61 GWASARFGGRTVFLTGLGLFLLGSLLCTAARSP-GMLIGFRALQGFGGGLLEPSAMTLSA 119 G S + G + + L G+ + GS++ S +LI R +QG G M + A Sbjct: 70 GKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVA 129 Query: 120 ALATRESMGRVLGVMSTVVNVAPAAGPILGGLLLETGHWQWLFGVNIPLGLLVGAATLAY 179 +E+ G+ G++ ++V + GP +GG++ HW +L IP+ ++ L Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMK 187 Query: 180 VPAGRPDPAAARPGADLRGLALLTAGYLGVLFAVNRAGEQSGDWPVPAAAAGGIVLLVAY 239 + + D++G+ L++ G + + S + ++ + + Sbjct: 188 LL---KKEVRIKGHFDIKGIILMSVGIVFFMLFTT-----SYSISFLIVS---VLSFLIF 236 Query: 240 VRHAVTTTAVPALDLRLLRRPGFAASVAVMGLVGLIMYGQTTALPVVGLDQHGLHGFDQG 299 V+H T P +D L + F V G++ + G + +P + D H L + G Sbjct: 237 VKHIRKVTD-PFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIG 295 Query: 300 LLVCALG-LGLLVSMTTGGRLSDRLGARSLVRSGAVASAVLLATFAASAEHLPLAAACAL 358 ++ G + +++ GG L DR G ++ G +V T + E + Sbjct: 296 SVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIII 355 Query: 359 -FVAVGLSFGLTASPTVASLYRTLPPAEQPQGTTSIFMAVQFAASLGVALLSLL 411 FV GLSF T T+ S +L E G + + + G+A++ L Sbjct: 356 VFVLGGLSFTKTVISTIVS--SSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.6 bits (162), Expect = 1e-15 Identities = 38/171 (22%), Positives = 65/171 (38%), Gaps = 7/171 (4%) Query: 3 GRQRGVDKRRAILDAAAPIFGTQGYERASVDAIATAAGVSKPTIYSYFGGKENLFRESVA 62 +Q + R+ ILD A +F QG S+ IA AAGV++ IY +F K +LF E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE-IW 63 Query: 63 DSAVEQNGDALRVLQTLDVSPERWQASLFEVGVKLVECQRSSCSMFLYRTI---AAESAR 119 + + G+ + P + L E+ + ++E + L I E Sbjct: 64 ELSESNIGELEL--EYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 120 DPEIYRTVREKAGDPILDALTGRLAMLGNAGLLQVA-DPALAARQFFALIN 169 + + + + D + L A +L AA I+ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 1e-16 Identities = 38/205 (18%), Positives = 68/205 (33%), Gaps = 20/205 (9%) Query: 8 RPLRADARRNRDQVLDAALRAFSAGGP-GVPLEAVARDAGVGIATLYRHFPTREVLVEAV 66 R + +A+ R +LD ALR FS G L +A+ AGV +Y HF + L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 67 YRAELGRLCDAAPALLGRLP--PAAALRAWMDAFLDYTTAKRGMADALRAV----IASGG 120 + + + + P P + LR + L+ T + + + G Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 121 DPFAHTRKR-----MVAAVTSLLAAGDAAGTVRADVDP-------VDVLTGLAGVTLAAG 168 +R + L A + AD+ ++GL L A Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 169 EPAQRAQAGRLL-DLFMDGLRPRAT 192 + + R + ++ T Sbjct: 183 QSFDLKKEARDYVAILLEMYLLCPT 207
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 75.9 bits (186), Expect = 4e-18 Identities = 52/206 (25%), Positives = 79/206 (38%), Gaps = 20/206 (9%) Query: 24 LSGRRAVVTGASSGIGVETARALAGAGAQVTITVRDLDAGARVAADITASTGSDQVTVAP 83 + G+ A +TGA+ GIG AR LA GA + D + + + P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAV--DYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 84 LDLAQPASVAAFVNGWQ---GPLHILVNNAGV--MAAPETRTSQGWELQFATNHLGHFAL 138 D+ A++ + GP+ ILVN AGV + + + WE F+ N G F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 139 TTGLRPALAAAGGARVVSVSSSAHLRSDVVFDDIHFLARPYEPWAAYGQSKTANVLFAVE 198 + + + +V+V S+ P AAY SK A V+F Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNP-------------AGVPRTSMAAYASSKAAAVMFTKC 170 Query: 199 ATRRWADDGIAVNALMPGGIRTKLQR 224 A+ I N + PG T +Q Sbjct: 171 LGLELAEYNIRCNIVSPGSTETDMQW 196
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 33.6 bits (76), Expect = 0.004 Identities = 24/69 (34%), Positives = 32/69 (46%), Gaps = 9/69 (13%) Query: 155 AGLVHRDLTPTNVLLSPLGAR--VIDFGLARVSDEAPSGPSGRVAGTPAFMSPEQARGET 212 AG+VH D+ P NV+ VID GL S E P G T +F +PE G Sbjct: 264 AGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKG------FTESFKAPELGVGNL 317 Query: 213 -VTSAADIF 220 + +D+F Sbjct: 318 GASEKSDVF 326
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 3e-12 Identities = 19/104 (18%), Positives = 38/104 (36%) Query: 4 PGRTSYHHGDLAAALVDGALDLIAEGGLAAFSVAAVARRVGVSSAAPYRHFPDRDSLLAA 63 +T + ++D AL L ++ G+++ S+ +A+ GV+ A Y HF D+ L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 64 AAAAAAGQLTGQVRAAADSAGADPVQRLAATAGAYTRFVIERRA 107 + + DP+ L + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER 105
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 35.2 bits (81), Expect = 0.001 Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 4/96 (4%) Query: 237 FAVMIAVGVSLGAAVVVVHRCQAEMRAGR-QPLDAVAASLVQSGRPLTRGGLGLAVVMLG 295 F +++A+G+ + A+VVV + M + P +A S+ Q L + L+ V + Sbjct: 396 FGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIP 455 Query: 296 TSALRGSVLAGLAPAAF---VAAAVASLAIATLLPA 328 + GS A + A A++ L L PA Sbjct: 456 MAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPA 491 Score = 34.0 bits (78), Expect = 0.003 Identities = 14/84 (16%), Positives = 31/84 (36%), Gaps = 4/84 (4%) Query: 642 PDGEDPATAIRSGHADVGPVVVAASLIVIAVF---AGLACQQVRTMKLLGLGLAVGVALD 698 D P A + + +V ++++ AVF A + + + +AL Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL- 480 Query: 699 ALVLRVLLLPALVHLTRDAAGRRP 722 ++++ ++L PAL Sbjct: 481 SVLVALILTPALCATLLKPVSAEH 504
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 49.7 bits (118), Expect = 6e-09 Identities = 33/114 (28%), Positives = 57/114 (50%), Gaps = 8/114 (7%) Query: 8 LAGRTAIVTGASRGLGRAIALAFAREGAAVAVVARTEAQWDARLPGTVHEVVEEIVKDGG 67 + G+ A +TGA++G+G A+A A +GA +A V P + +VV + + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYN--------PEKLEKVVSSLKAEAR 57 Query: 68 RALAVPADLSRPADVERIVEVTRARLGPVDLLVNNAALTVPGRPPAQPQPQSQS 121 A A PAD+ A ++ I +GP+D+LVN A + PG + + ++ Sbjct: 58 HAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEA 111 Score = 44.7 bits (105), Expect = 2e-07 Identities = 22/84 (26%), Positives = 34/84 (40%), Gaps = 9/84 (10%) Query: 208 FEIGLFASYRLMQLVLPDMIDLGRGSIVNISSVAGFIPGEGPYAAPGTPGPIAYGGNKAA 267 F + + + V M+D GSIV + S +P AY +KAA Sbjct: 113 FSVNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVP---------RTSMAAYASSKAA 163 Query: 268 LHHLTQAVAIEAQAYGIAVNVLSP 291 T+ + +E Y I N++SP Sbjct: 164 AVMFTKCLGLELAEYNIRCNIVSP 187
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 49.7 bits (118), Expect = 2e-09 Identities = 49/244 (20%), Positives = 84/244 (34%), Gaps = 29/244 (11%) Query: 1 MRRFVQAGAKVVIADLAADKGKTLADELGEQAVF---VPTDVTSDESVEAAIAA-AVELG 56 R GA + D +K + + L +A P DV +++ A E+G Sbjct: 25 ARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAIDEITARIEREMG 84 Query: 57 PLRAAVVVHGGPAAGKRLVNRAGQAYPVETFQRTIDIFLVGTFRVVSKVAGAMSQNEPLD 116 P+ V V G G + E ++ T + G F V+ M Sbjct: 85 PIDILVNVAGVLRPG------LIHSLSDEEWEATFSVNSTGVFNASRSVSKYMM------ 132 Query: 117 SNQRGVIITTASIAGFEGQVGQTDYSAAKGGVIGFNLTAARDLAPTGIRVVCIAPGTFFT 176 + G I+T S + Y+++K + F +LA IR ++PG+ T Sbjct: 133 DRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGSTET 192 Query: 177 PAYRM----EEAEAQ------AKWGPGVPNPKRMGHADEYAKLALSIVDND--YINGETI 224 E Q + G+P K++ + A L +V +I + Sbjct: 193 DMQWSLWADENGAEQVIKGSLETFKTGIP-LKKLAKPSDIADAVLFLVSGQAGHITMHNL 251 Query: 225 RIDG 228 +DG Sbjct: 252 CVDG 255
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 60.7 bits (147), Expect = 2e-13 Identities = 39/153 (25%), Positives = 58/153 (37%), Gaps = 14/153 (9%) Query: 1 MPRLAAFLDVGVTSIYWYYKSKRDLLDAMTEEALAAFYESMPPLRAGGWEDMLRGFFDDC 60 +LA L + ++YW+ K+KR LLDA+ E LA ++ P W+ LR Sbjct: 27 TRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARHHDYSLPAAGESWQSFLRN----- 81 Query: 61 YAALAADDLTCDLIVRRIGGATRQDAVAAWPR---AAELLDGLREAGFPPSLAWHAFITL 117 A L+ R G + L + E GF +A + Sbjct: 82 ----NAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRFMTENGFSLRDGLYAISAV 137 Query: 118 AAYTRGFLLTEQPAEAPPASARRPAVTAAAAPP 150 + +T G +L +Q A A RPA PP Sbjct: 138 SHFTLGAVLEQQEHTA--ALTDRPAAPDENLPP 168
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 25.9 bits (56), Expect = 0.029 Identities = 14/38 (36%), Positives = 20/38 (52%), Gaps = 5/38 (13%) Query: 28 SPPGPWRP---ADRVRRVAWWPVGRGRRGGSSGGPWGV 62 S P PWRP ADR+ + ++ G GG + WG+ Sbjct: 90 SMPPPWRPGEHADRITNLKFFKQFDGYVGGQTA--WGI 125
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 28.8 bits (64), Expect = 0.033 Identities = 14/71 (19%), Positives = 16/71 (22%) Query: 313 PATTPAAQAAAPAAAQSAAPSTTQNATPPATRPVPATESTSPPPPAPTSAAPAPTTAPVH 372 PA QA P P P + P P P P P Sbjct: 57 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 373 TTVPVPTGGQP 383 PV + Sbjct: 117 DVKPVESRPAS 127
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.1 bits (153), Expect = 3e-14 Identities = 30/175 (17%), Positives = 61/175 (34%), Gaps = 11/175 (6%) Query: 1 MRGQGEQLRREILAAVNHLLVEWGSAEKLTMRAVAREVGVAAPSIYLHFPDKAALVWAAL 60 + + ++ R+ IL L + G ++ +A+ GV +IY HF DK+ L Sbjct: 5 TKQEAQETRQHILDVALRLFSQQG-VSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 61 SDKYDDLVASMARADEATDDTDPREPLRAQTHAYCRFALTNPGHYRLMFEVPQPTVE--- 117 ++ + +A DP LR +T RL+ E+ E Sbjct: 64 ELSESNI-GELELEYQAKFPGDPLSVLREILIHVLESTVTEE-RRRLLMEIIFHKCEFVG 121 Query: 118 ----IARISEHPAHGVSASLRAGFRRCRQSGY-ALSLPVEQAAQTLWAGLHGMVT 167 + + + + + C ++ L +AA + + G++ Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME 176
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.1 bits (67), Expect = 0.021 Identities = 17/63 (26%), Positives = 22/63 (34%) Query: 405 PSADKTPSTGQAPGTGQAPGTGQAPGTGQAPGTGQAPGTGQAPSGRQVPSARQVPVADSA 464 P D TP + +AP P A P + PGT P + P D Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370 Query: 465 PGS 467 PG+ Sbjct: 371 PGT 373
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 35.4 bits (81), Expect = 4e-04 Identities = 15/36 (41%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 287 NPQHPQHPQHPDSPHNPHGNPPSSHSPLNRDDPHVP 322 N P +P +PD+P+NP NP + P N D+P+ P Sbjct: 285 NDDQPNNPDNPDNPNNPD-NPNNPDEPNNPDNPNNP 319 Score = 33.1 bits (75), Expect = 0.002 Identities = 17/48 (35%), Positives = 26/48 (54%), Gaps = 3/48 (6%) Query: 273 ADQTLDLPD-PHSQHNPQHPQHPQHPDSPHNPHGNPPSSHSPLNRDDP 319 D PD P++ NP +P P +PD+P+NP + P + N D+P Sbjct: 288 QPNNPDNPDNPNNPDNPNNPDEPNNPDNPNNP--DNPDNGDNNNSDNP 333
>PF04183#IucA / IucC family Length = 580 Score = 29.1 bits (65), Expect = 0.027 Identities = 9/50 (18%), Positives = 12/50 (24%) Query: 5 ERVLDRLEREQALDAVAGRAHAFWSKALRSPRLRDLLSGRALGHPLHPAA 54 + L D +A S + D L GHP Sbjct: 93 AEHMQDLYATLLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFN 142
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 34.0 bits (77), Expect = 0.001 Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 13/81 (16%) Query: 54 PIIDRPGVPAGYITAIQVRDDAGRV---IAVLPAA--SPG---ATSARPVPSARPSLQPG 105 P+ DR G P + A RD G + V+P +PG A +A+P+P P+ P Sbjct: 280 PVTDRNGNPV-QVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPA 338 Query: 106 SAP----QPGVVPRQPPPRDL 122 + P PG P P DL Sbjct: 339 NNPAPNENPGTRPNPEPDPDL 359 Score = 29.3 bits (65), Expect = 0.030 Identities = 15/47 (31%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 82 LPAASPGATSAR-PVPSARPSLQPGSAPQPGVVPRQPPPRDLRVASR 127 LP SP A P P+ P +P P P + P P D + +R Sbjct: 328 LPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTR 374
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.7 bits (142), Expect = 2e-12 Identities = 31/138 (22%), Positives = 56/138 (40%), Gaps = 8/138 (5%) Query: 6 LRAEGFDVDVVHDGLEGYWQAREGAHDVVVLDILLPSMTGYAVAARLRAEKVWTPLLMLT 65 L G+DV + + + G D+VV D+++P + + R++ + P+L+++ Sbjct: 23 LSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLPVLVMS 82 Query: 66 AKDGDYDEADGLDAGADDYLRKPFSF-VVLTARLRALARRGASPRPRLLSHGGLVLDPES 124 A++ + GA DYL KPF ++ RALA P D + Sbjct: 83 AQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLE-------DDSQD 135 Query: 125 GDCSVGAAPVSLQPRERA 142 G VG + + Sbjct: 136 GMPLVGRSAAMQEIYRVL 153
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 129 bits (327), Expect = 5e-35 Identities = 93/407 (22%), Positives = 170/407 (41%), Gaps = 18/407 (4%) Query: 12 FVSMLSTTIVTNALPTIMADLHGSATGYTWVVTAHLLAMTASMPIWGKLADLVDKKRLVQ 71 F S+L+ ++ +LP I D + WV TA +L + ++GKL+D + KRL+ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 72 SALGVFVLGSVLAGLAGSP-GMLIACRFVQGVGGGGMSALVQVAMGAIIPARDRGRYNGY 130 + + GSV+ + S +LI RF+QG G ALV V + IP +RG+ G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 131 VGATFAVATVTGPLVGGLVVDAPWLGWRWCFYLSLPIAALAGVLIQRTLRLPVGTREVSI 190 +G+ A+ GP +GG++ W + L +P+ + V L + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY----IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHF 199 Query: 191 DYAGALLISGGACCLLIWVSLAGGAFGWASAQTGWLVGGGVLLLAVAVAVEFRVREPMIP 250 D G +L+S G +++ + +F S VL + V +V +P + Sbjct: 200 DIKGIILMSVGIVFFMLFTTSYSISFLIVS----------VLSFLIFVKHIRKVTDPFVD 249 Query: 251 PRLFRDRTLVLCVVAAFCIGTVMFSTPVMLSQYFQLGQGRSP-VISGLLAVPLVGAMAYA 309 P L ++ ++ V+ I + M+ + S I ++ P ++ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 310 SLHVGRVISRSGRWKRFLVLGCGLVLAGLLLLGLVGPTTTPVLVGLAMVPVGLGLGLVQQ 369 G ++ R G L +G + L + TT + + +V V GL + Sbjct: 310 GYIGGILVDRRGPLY-VLNIGVTFLSVSFLTASFL-LETTSWFMTIIIVFVLGGLSFTKT 367 Query: 370 NVIVIAQNTAPLADLGAASATVQFIRSLGGTTGVAVLGALIAHRITD 416 + I ++ + GA + + F L TG+A++G L++ + D Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLD 414
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.9 bits (69), Expect = 0.015 Identities = 17/41 (41%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Query: 384 LPAPSSAPSSASAPSSASAPAPSSAPTLALAPAPGP-PGAR 423 +P P P SA AP++ P S A A PAP PG R Sbjct: 310 IPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTR 350
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 35.8 bits (82), Expect = 8e-04 Identities = 33/149 (22%), Positives = 57/149 (38%), Gaps = 22/149 (14%) Query: 581 WVENGVEPNGSH-YTFV-DGRVHLPSSAAQRGGIQPVASVTANGGARADVGVGEPVTLTV 638 +V + V+ NG++ Y V G ++ +P A + ++ + V V E + Sbjct: 741 FVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNK-EPKAVIKSD----SSVIVEEEINFDG 795 Query: 639 TAAVPPGAGRIIAVEWDFDGTGTYPLRHAGIDGTAAELTVSTTHAYDRPGTYFATARVTS 698 T + G I A EWDF DG + TH Y++ G Y VT Sbjct: 796 TESKDED-GEIKAYEWDFG------------DGEKSNEA-KATHKYNKTGEYEVKLTVTD 841 Query: 699 HRTGDVAAQRCRIETIAQARTVVAAPAAP 727 + G + + +I+ + V + P Sbjct: 842 NN-GGINTESKKIKVVEDKPVEVINESEP 869
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 95.1 bits (236), Expect = 2e-25 Identities = 69/263 (26%), Positives = 113/263 (42%), Gaps = 15/263 (5%) Query: 2 AGSLKGKIVLITGTGSGMGRAGALRFAAAGATVVGADLNAEGNAETEALVTAAGGRMLGT 61 A ++GKI ITG G+G A A A+ GA + D N E + + + A R Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEA 61 Query: 62 APVDLGDYAACKRWVDAAVRTHGRIDVLWNNASACVFATIEAMTVEQWDFSIRNELSIVF 121 P D+ D AA R G ID+L N A I +++ E+W+ + + VF Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 122 LVTKAAWPHLTASAGAGADARPVVINTASVAGHGGGPGGIAHSATKAAVLAMTHVIAAEG 181 +++ ++ ++ S A++++KAA + T + E Sbjct: 122 NASRSVSKYMMDRRSGS------IVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL 175 Query: 182 APYGIRAVSISPGAMDT--------PGSAEQLALPGAREALLSHALVPRLGDPDEVARAA 233 A Y IR +SPG+ +T + + + G+ E + + +L P ++A A Sbjct: 176 AEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAV 235 Query: 234 VFLASADASFITGADLLVDGGLT 256 +FL S A IT +L VDGG T Sbjct: 236 LFLVSGQAGHITMHNLCVDGGAT 258
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 81.3 bits (200), Expect = 2e-20 Identities = 71/261 (27%), Positives = 119/261 (45%), Gaps = 17/261 (6%) Query: 5 LAGRRAIVTGGSRGIGRAVARALLAEGVQVVIAARDVDVLKSAAAELSAAG-GATVLPIV 63 + G+ A +TG ++GIG AVAR L ++G + + + L+ + L A A P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA- 64 Query: 64 TDTASDASVQALVESTVAELGGVDILVNNAARPGGAGGPGGVTALSTADAAADFNVKVLG 123 D A++ + E+G +DILVN A G PG + +LS + A F+V G Sbjct: 65 -DVRDSAAIDEITARIEREMGPIDILVNVA----GVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 124 YLRTAQAVAPHFVAQGWGRIINIGGLAAR--QVGLASGSIRNVGVAALTKTLADELGPHG 181 +++V+ + + + G I+ +G A + +A+ + TK L EL + Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 182 VTVNVVHPGLTLT-------ADHGGSVVLSEEQIQAAATRIAIGRAVTADEVAAVVTFLA 234 + N+V PG T T AD G+ + + ++ T I + + ++A V FL Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 235 SPLAVAVTGEAIAA-GGGTLG 254 S A +T + GG TLG Sbjct: 240 SGQAGHITMHNLCVDGGATLG 260
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.1 bits (62), Expect = 0.049 Identities = 17/103 (16%), Positives = 26/103 (25%), Gaps = 15/103 (14%) Query: 9 APTTPVTGASGAAAPHEAPSQKAPSQKAPSEGRQGSPWAGVSPAEGGEWPRPVPVRTVEQ 68 A + T A+G A E P ++ PS A ++ GG P Sbjct: 385 ADVSSPTAAAGGAGGGEPPKKRDPSAGAGTD----------PGGPGGGDDGEDPFGEWLD 434 Query: 69 ERLHRKQKLAAAYRIFAKLGLAEGLAGHITARDPELTDHFWVN 111 + + R L P L + Sbjct: 435 D-----EVARLRLRGRWLLKPRRAALIEALRSAPALAGCVAFD 472
>PF07132#Harpin protein (HrpN) Length = 356 Score = 31.6 bits (71), Expect = 0.008 Identities = 17/61 (27%), Positives = 23/61 (37%), Gaps = 2/61 (3%) Query: 535 MGGGGVASGLVATARAAGRVAAA--GGAGAGGAGTGGGGGVGRAPGSDGSDGSDGADPPA 592 M GGG+ GL + G + GG GG G+ G G+G A G Sbjct: 64 MMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGAGMNAM 123 Query: 593 D 593 + Sbjct: 124 N 124
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 42.8 bits (100), Expect = 3e-06 Identities = 28/82 (34%), Positives = 44/82 (53%), Gaps = 8/82 (9%) Query: 144 QAGITHRDVKPANILVDEG-GRVVLVDFGVAVHASEPTITEGPIG-TLAYMAPEQFAGTR 201 +AG+ H D+KP N++ D G V++D G+ + E P G T ++ APE G Sbjct: 263 KAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQ-----PKGFTESFKAPELGVGNL 317 Query: 202 -MLPASDLFSLGATLYYAVEGF 222 SD+F + +TL + +EGF Sbjct: 318 GASEKSDVFLVVSTLLHCIEGF 339
>PF07675#Cleaved Adhesin Length = 1358 Score = 35.5 bits (81), Expect = 4e-04 Identities = 22/75 (29%), Positives = 28/75 (37%), Gaps = 6/75 (8%) Query: 130 TGTCYTAEQLTDGHTYEFRITGSNSTGESAPSPVARAIPVATSPPPSPPTGLTATPGNGT 189 T +Q+T+ Y+ IT SN PV + I P P + LTAT Sbjct: 294 VATVNMTKQITENGNYDVVITRSN------YLPVIKQIQAGEPSPYQPVSNLTATAQGQK 347 Query: 190 ARLCWTASSGADAHT 204 L W A S A Sbjct: 348 VTLKWDAPSAKKAEG 362 Score = 35.5 bits (81), Expect = 4e-04 Identities = 22/75 (29%), Positives = 28/75 (37%), Gaps = 6/75 (8%) Query: 224 TGTCYTAEQLTDGHTYEFRITGSNSTGESAPSPVARAIPVATSPPPSPPTGLTATPGNGT 283 T +Q+T+ Y+ IT SN PV + I P P + LTAT Sbjct: 294 VATVNMTKQITENGNYDVVITRSN------YLPVIKQIQAGEPSPYQPVSNLTATAQGQK 347 Query: 284 ARLCWTASSGADAHT 298 L W A S A Sbjct: 348 VTLKWDAPSAKKAEG 362
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.7 bits (82), Expect = 8e-04 Identities = 22/119 (18%), Positives = 35/119 (29%), Gaps = 5/119 (4%) Query: 1086 AGSEPLAGSAVAADPFAEPGPVAVPGRVAEPGPVAVPGRVVVPGPVAASESDATPAPNRG 1145 A ++P++ + V P V P P P P Sbjct: 40 APAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK-- 97 Query: 1146 RFPVATPEQAAGTGPFAASKPGPSSPGSSPGSSSRRAGTGSGAGSVAGPRRTTTASGLP 1204 P P + P KP S P S +++ A S + A + T+ + P Sbjct: 98 --PKPKPVKKVQEQPKRDVKPVESRPASPFENTA-PARLTSSTATAATSKPVTSVASGP 153
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 35.5 bits (81), Expect = 7e-04 Identities = 54/200 (27%), Positives = 86/200 (43%), Gaps = 43/200 (21%) Query: 98 RSLADAVATRGELDDRLVHG----LAIGLADALVAIHAAGVVHRDLKPANILL--AWDGP 151 R+LAD+ +G+++ G +A L D + AGVVH D+KP N++ A P Sbjct: 227 RTLADS-WKQGKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEP 285 Query: 152 KVIDFGIARAGDSTSHTRTGMLIG--TLVWMAPEQLRGER-AGPPADIFAWGACVAFAAA 208 VID G+ H+R+G T + APE G A +D+F + + Sbjct: 286 VVIDLGL--------HSRSGEQPKGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIE 337 Query: 209 G---RPPFRGERAEAVGMQILTAEP----DLDGLP---PDLVGVVRAALEKEPARRPTAS 258 G P + + G++ +T+EP D +G P P + GV A + Sbjct: 338 GFEKNPEIKPNQ----GLRFITSEPAHVMDENGYPIHRPGIAGVETA-----------YT 382 Query: 259 ELLRRLVGRDVRSPADSDEA 278 + ++G S DS+EA Sbjct: 383 RFITDILGVSADSRPDSNEA 402
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 34.3 bits (78), Expect = 0.002 Identities = 33/105 (31%), Positives = 49/105 (46%), Gaps = 14/105 (13%) Query: 70 VHGRAVAAVLDADPEA-----VAPWLATEYVEGTSLADAVLRHGRMEERLLHGFSVGLAD 124 VHG AV + EA V W ++ + +LAD+ + G++ G +A Sbjct: 196 VHGMAVVPYGNRKEEALLMDEVDGWRCSDTLR--TLADS-WKQGKINSEAYWGTIKFIAH 252 Query: 125 ALIAI----HAAGVVHRDLKPSNILL--AWDGPKVIDFGIARASG 163 L+ + AGVVH D+KP N++ A P VID G+ SG Sbjct: 253 RLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSG 297
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 36.9 bits (85), Expect = 2e-04 Identities = 15/43 (34%), Positives = 15/43 (34%) Query: 742 PPPAPPATRPPTATPPAPTAEPSSSAPTPKPTPKPTPKPTPKP 784 PP P P P EP P P PKP PKP Sbjct: 56 EPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98 Score = 35.7 bits (82), Expect = 4e-04 Identities = 15/45 (33%), Positives = 16/45 (35%) Query: 742 PPPAPPATRPPTATPPAPTAEPSSSAPTPKPTPKPTPKPTPKPTK 786 PP P P P P + KP PKP PKP P Sbjct: 62 QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKV 106
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 9e-14 Identities = 37/202 (18%), Positives = 66/202 (32%), Gaps = 27/202 (13%) Query: 1 MRADAQRNRELIATTALDLLARRGP-SVSMEEIARAAGLGVGTLYRHFPDRQSLLDSVAA 59 + +AQ R+ I AL L +++G S S+ EIA+AAG+ G +Y HF D+ L + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 60 TTLRTL--LAAGRAEQSSTRPRWQVLVRIVARCTGL------------PLALISSLPDAT 105 + + L + P + ++ + + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMA 124 Query: 106 RVDPTVAELVAELDALFQGLVEDAQREGSLRADLT--------GAQVVGLLNVAVCRPG- 156 V L E + ++ L ADL + GL+ + P Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184 Query: 157 ---ARADDPLTTVLLDGLRARP 175 + +LL+ P Sbjct: 185 FDLKKEARDYVAILLEMYLLCP 206
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 111 bits (279), Expect = 2e-31 Identities = 86/276 (31%), Positives = 133/276 (48%), Gaps = 26/276 (9%) Query: 10 LAGKVAFITGIARGQGRSHAVALAREGADIIGIDRAADVATMGYPLGTADELAETVALVE 69 + GK+AFITG A+G G + A LA +GA I +D Y +++ ++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVD---------YNPEKLEKVVSSLKAEA 56 Query: 70 RTGRRIIARVGDVRDRAAIVDLLATGVRELGGLDIVVASAGISPPARRLWEIPPEQWDDV 129 R A DVRD AAI ++ A RE+G +DI+V AG+ P + + E+W+ Sbjct: 57 RHAEAFPA---DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGL-IHSLSDEEWEAT 112 Query: 130 IGINLTGVFHTLAASVPHLLAGRRGGSIIVISSGAALNRVPNLSDYVTTKNGVIGMAMSL 189 +N TGVF+ + SV + RR GSI+ + S A +++ Y ++K + L Sbjct: 113 FSVNSTGVFN-ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171 Query: 190 ANEVAHRQIRVNVIAPGTVNTPMVTENTQQFHLFRPDLPNPTVDDCRDGFAASMPMGRPW 249 E+A IR N+++PG+ T M Q+ L+ + V G + G P Sbjct: 172 GLELAEYNIRCNIVSPGSTETDM------QWSLWADENGAEQV---IKGSLETFKTGIPL 222 Query: 250 ---LEPEDISSAVVFLSSDEARWISGVVLPVDQGNT 282 +P DI+ AV+FL S +A I+ L VD G T Sbjct: 223 KKLAKPSDIADAVLFLVSGQAGHITMHNLCVDGGAT 258
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (300), Expect = 8e-35 Identities = 72/252 (28%), Positives = 119/252 (47%), Gaps = 7/252 (2%) Query: 9 MSGKVALVTGGGYGMGRASARRFAECGAAVVVADINPDTGAETVELIRAAGGQATFVHAD 68 + GK+A +TG G+G A AR A GA + D NP+ + V ++A A AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 VGEPEAVRDMVDRTVATYGGLDYAHNNAGIVESQDPVVSYPEQLWERILRTNLTSVFLCL 128 V + A+ ++ R G +D N AG++ + S ++ WE N T VF Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 129 KYEIPRMLERGGGAIVNVASESTYKGNVADIGYTASKHGVVGLTTAAALQYARRNIRVNA 188 + M++R G+IV V S + Y +SK V T L+ A NIR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 189 VAPGNVDTGIVER--ARQYLTPEQLR-SMEQAQ---PIRRLSRPEEIAEVVVWLCSDAAV 242 V+PG+ +T + A + + ++ S+E + P+++L++P +IA+ V++L S A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 243 LVNAAKIAADTG 254 + + D G Sbjct: 245 HITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.9 bits (155), Expect = 6e-15 Identities = 29/178 (16%), Positives = 61/178 (34%), Gaps = 9/178 (5%) Query: 1 MPSRLTSKGSATRQRIIEGAAAEIRERGVSVTTLDDVRARTGTSKSQLFHYFPTGKEELL 60 M + + TRQ I++ A ++GVS T+L ++ G ++ ++ +F K +L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD-KSDLF 59 Query: 61 LAVARFEADRVLADQQPQLGDLTSWSAWLAWRDKVVA--RYREQGRHCPLSVLVSQLGRS 118 + + + R+ ++ L + + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLS-VLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 119 TPGAQAVVRELMNRWQAE----IVTGIRAMQRAGEISPLLDAEPHAAALIAGIQGGVL 172 G AVV++ E I ++ A + L AA ++ G G++ Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTR-RAAIIMRGYISGLM 175
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 98.2 bits (244), Expect = 1e-26 Identities = 71/254 (27%), Positives = 116/254 (45%), Gaps = 14/254 (5%) Query: 7 LAGRSALVTGSTDGIGAAIAAELAAAGAHVVVSGRDAGRGAEVTRVIGAAGGRATFVPAD 66 + G+ A +TG+ GIG A+A LA+ GAH+ + + +V + A A PAD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 LAAGAPAVQALADAARAAVGGVPDILVNNAAMLITPKPTAEVGEAVITAALAVNVTATFL 126 + A A+ + +G + DILVN A +L P + + A +VN T F Sbjct: 66 VRDSA-AIDEITARIEREMGPI-DILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 127 LTGAIAPAMAARSSGAVINIGSINGLVGMDGSALYSATKAAVHSLTKSWAAEYGPAGVRV 186 + +++ M R SG+++ +GS V A Y+++KAA TK E +R Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 187 NTVAPGPTLTRR-----IEQYAD--RVAPLVAR----APSRRPSRPAEIGRVVVFLAGDD 235 N V+PG T T ++ + + P ++ ++P++I V+FL Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 236 AANIHGATLSVDGG 249 A +I L VDGG Sbjct: 243 AGHITMHNLCVDGG 256
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 1e-15 Identities = 40/188 (21%), Positives = 68/188 (36%), Gaps = 11/188 (5%) Query: 2 QAEITAVAFDLFDRQGFEATTINQIAAEAGLSRSSFFRYFATKEDVVLLGVEERGLVLRD 61 + I VA LF +QG +T++ +IA AG++R + + +F K D+ E + + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 62 ALAGRPAD--ETPWQALRQALNAIIGVNAENPERALRLSRMMVDTPSLQGRQLQRQNSWQ 119 A P LR+ L ++ R RL ++ ++ Q Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERR--RLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 120 RLLAPELARRLA-------IAPTDTADPRPRALASAALGCYDAALTVWRDSDGTADLAAL 172 R L E R+ A AD R A G + W + + DL Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 173 LDRAMSVL 180 +++L Sbjct: 191 ARDYVAIL 198
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.6 bits (162), Expect = 9e-16 Identities = 43/208 (20%), Positives = 72/208 (34%), Gaps = 6/208 (2%) Query: 1 MGVRRARAAETELALKEAARRLFVERGYLNTKISDITAAAGRATGSFYDHFAGKEELLAA 60 + A ET + + A RLF ++G +T + +I AAG G+ Y HF K +L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 LLADLRGAASAEMRRSEHPRDHDLTD--RDQLHDHLAVAWRVMRENLPVVVALHEASLTG 118 + + D R+ L L R L + + H+ G Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 119 GHAPDQAWRSLVTE--TDMLRDHLEYLRESGHELPG-DPILLAAAMGGLLSTLALALLRS 175 A Q + + D + L++ E+ A M G +S L L + Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 176 PTPAYSDAEVLDTLTTLLLNGLRGAPTD 203 P ++ + +LL PT Sbjct: 182 PQ-SFDLKKEARDYVAILLEMYLLCPTL 208
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.7 bits (66), Expect = 0.024 Identities = 33/122 (27%), Positives = 45/122 (36%), Gaps = 7/122 (5%) Query: 303 PHTREFFPVLPAAQAALGPARRLDAGLADLVAALGRWTEATLSDDVALLAAEFAPPTRAT 362 P E V P + +GP + +VA GR ++ + DV ++ P A Sbjct: 262 PGYSEKVEVAPGTKVNMGPVTDRNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAE 321 Query: 363 TPAADQPAREAAVHGAGAPWRAPT-GAREGSRPVAGCSSTAPMTPGAAAAT-GSPGAGAG 420 P A QP E V A P P G+RP + P A T G PG Sbjct: 322 APNA-QPLPE--VSPAENPANNPAPNENPGTRP--NPEPDPDLNPDANPDTDGQPGTRPD 376 Query: 421 AP 422 +P Sbjct: 377 SP 378
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 68.7 bits (168), Expect = 2e-15 Identities = 38/171 (22%), Positives = 59/171 (34%), Gaps = 25/171 (14%) Query: 1 MRVLVTGSRGKIGSRVVARLGADGHQVTGTDIVAAHYGPPFDPY------------LRAD 48 M+ LVTG+ G IG V RL GHQV G D + +Y + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 49 LTDYGQAVAVVLRTRPDVVIHT---AGIPEPSHDPGHVIFATNTQSTYHVAEAVARTRVP 105 L D + + V + + +P H +N ++ E ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENP-HAYADSNLTGFLNILEGCRHNKIQ 119 Query: 106 RLIYTSSETAPGFVTAERPFLPDYLPVDEDHPL-RPQDAYGLSKALGENIC 155 L+Y SS + G L +P D + P Y +K E + Sbjct: 120 HLLYASSSSVYG--------LNRKMPFSTDDSVDHPVSLYAATKKANELMA 162
>PERTACTIN#Pertactin signature. Length = 922 Score = 38.2 bits (88), Expect = 5e-05 Identities = 23/74 (31%), Positives = 26/74 (35%), Gaps = 9/74 (12%) Query: 158 FTPLPATDWTTTVRPAPTAPATGRQPMNPPRQPPRPGPPPYQPPRTGPRYQGSPPPPYQN 217 W+ AP AP QP P P P P QPP+ PP Sbjct: 552 LAANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQ---------PPQPPQ 602 Query: 218 PRPGPPYPQPPPYR 231 +P P PQPP R Sbjct: 603 RQPEAPAPQPPAGR 616 Score = 33.5 bits (76), Expect = 0.002 Identities = 21/64 (32%), Positives = 26/64 (40%) Query: 169 TVRPAPTAPATGRQPMNPPRQPPRPGPPPYQPPRTGPRYQGSPPPPYQNPRPGPPYPQPP 228 T R A G+ + + PP P P P P+ GP+ P PP P PP QP Sbjct: 547 TYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPE 606 Query: 229 PYRP 232 P Sbjct: 607 APAP 610 Score = 31.2 bits (70), Expect = 0.007 Identities = 25/74 (33%), Positives = 28/74 (37%), Gaps = 7/74 (9%) Query: 245 PPYRASGTGPYYRQSAPPPYRTGPAMPPNPYQAPGYGPQYRQPGPPVGRVPTDPIAFAAL 304 PP P + PP P PP P Q P P+ P PP GR A AA+ Sbjct: 568 PPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGR-ELSAAANAAV 626 Query: 305 RGGGR------WYA 312 GG WYA Sbjct: 627 NTGGVGLASTLWYA 640 Score = 30.5 bits (68), Expect = 0.014 Identities = 16/41 (39%), Positives = 18/41 (43%), Gaps = 2/41 (4%) Query: 210 SPPPPYQNPRPGPPYPQPPPYRPPGTGPYYRQPAPPPYRAS 250 +PP P P+PGP PP P P QP PP R Sbjct: 567 APPAPKPAPQPGPQPGPQPPQPPQPPQP--PQPPQPPQRQP 605
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 32.3 bits (73), Expect = 0.003 Identities = 24/105 (22%), Positives = 36/105 (34%), Gaps = 2/105 (1%) Query: 65 APADTADPPSAAPWEQPAGLPPAAARPGAPRPPEADGAKPAP-GEPAPGGLAEPPPPAGP 123 PAD P + P +P P P P EA P +P P P Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110 Query: 124 AEAPAGEPTRPADPWRLHSSPTAAPTVGRVLPPPRPVLAPATVFR 168 +RPA P+ +++P + +PV + A+ R Sbjct: 111 KRDVKPVESRPASPFE-NTAPARLTSSTATAATSKPVTSVASGPR 154 Score = 28.4 bits (63), Expect = 0.048 Identities = 23/97 (23%), Positives = 28/97 (28%), Gaps = 5/97 (5%) Query: 54 AAAPDAPAAPWAPADTADPPSAAPWEQPAGLPPAAARPGAPRPPEADGAKPAPGEPAPGG 113 A + P A P + P P P A P+P KP Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQ---- 107 Query: 114 LAEPPPPAGPAEAPAGEPTRPADPWRLHSSPTAAPTV 150 +P P E+ P P RL SS A T Sbjct: 108 -EQPKRDVKPVESRPASPFENTAPARLTSSTATAATS 143
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 42.3 bits (99), Expect = 2e-06 Identities = 17/75 (22%), Positives = 21/75 (28%) Query: 97 GSAAAAPTEAPAPAAEPEPEPEPAKPVAAAPPPPPAPTPAPAPAPVRAPEPAPVPAQAPT 156 P P P EP PEP PV P P V P+ P ++ Sbjct: 66 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRP 125 Query: 157 APAPVATSNGDGGIG 171 A T+ Sbjct: 126 ASPFENTAPARPTSS 140 Score = 34.2 bits (78), Expect = 8e-04 Identities = 28/143 (19%), Positives = 33/143 (23%), Gaps = 26/143 (18%) Query: 104 TEAPAPAAEPEPEPEPAKPVAAAPPPPPAPTPAP---APAPVRAPEPAPVPAQAPTAPAP 160 APA P P P P P P P APV +P P P P Sbjct: 52 VTMVAPADLEPP-QAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKK 110 Query: 161 VATSNGDGGIGRYVTPLVRKMAAELGVDLADVNGSGPGGRITKQDIQEAARSGGAPAAPA 220 V D S P S A Sbjct: 111 VEQPKRD----------------------VKPVESRPASPFENTAPARPTSSTATAATSK 148 Query: 221 PAAAPAAPAAPSAPARPAAPTAA 243 P + A+ + +P P A Sbjct: 149 PVTSVASGPRALSRNQPQYPARA 171
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 39.0 bits (91), Expect = 2e-05 Identities = 12/30 (40%), Positives = 17/30 (56%) Query: 4 MRIVVTGASGLIGSALVPALRGDGHTVTAL 33 M+ +VTGA+G IG + L GH V + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 1e-09 Identities = 20/109 (18%), Positives = 45/109 (41%), Gaps = 11/109 (10%) Query: 3 QVALLDQGVPAQLRVAADGVAAMTYLRALGAGRRVRRPDLILLDLNLPRRDGREVLAELK 62 AL G +R+ ++ ++ A DL++ D+ +P + ++L +K Sbjct: 20 NQALSRAG--YDVRITSNAATLWRWIAA-------GDGDLVVTDVVMPDENAFDLLPRIK 70 Query: 63 ADVDLRSIPVVVLTASAAEADVAACYDLQANAFVTKPANLDQFAEVVRR 111 +PV+V++A + A ++ KP +L + ++ R Sbjct: 71 K--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (261), Expect = 9e-29 Identities = 65/254 (25%), Positives = 111/254 (43%), Gaps = 11/254 (4%) Query: 38 GTVVLVTGAGRGLGRTIAEAFAVEGATVVVAARTARYGERTVREFRERGLSASLVIGDLA 97 G + +TGA +G+G +A A +GA + E+ V + A D+ Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 98 ERADVATMFDEAVARHGALDVVVHSAADNAQGLLAEIDDDTLDYLLRSNVHALHWITRAA 157 + A + + G +D++V+ A GL+ + D+ + N + +R+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 158 VPHLTRSKLPGRMIFISSGAANRVFSPGLNAYGSTKAYLESFARGLAGELGPLGVRVNVV 217 ++ + G ++ + S A V + AY S+KA F + L EL +R N+V Sbjct: 128 SKYMMDRR-SGSIVTVGSNPAG-VPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 218 GPGLTVT--ERMLGHLTHAQADALAST-------YPLGRAGLPEEIAAAVLFLASREASY 268 PG T T + L + + + PL + P +IA AVLFL S +A + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 269 ITGASLLVDGGASM 282 IT +L VDGGA++ Sbjct: 246 ITMHNLCVDGGATL 259
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.4 bits (73), Expect = 0.006 Identities = 39/148 (26%), Positives = 59/148 (39%), Gaps = 22/148 (14%) Query: 126 GIVHRDLKPANVLLGGDSPALHPRVTDFGIAAVMDASTELTTSQGILGTPTYMAPEMVSG 185 G+VH D+KP NV+ D + P V D G+ S +G T ++ APE+ G Sbjct: 265 GVVHNDIKPGNVVF--DRASGEPVVIDLGL-----HSRSGEQPKGF--TESFKAPELGVG 315 Query: 186 G-EVGPPADVYAAGIVLYELLSG------VTPFAGLMPLAVMRAHVDLLPGRP------P 232 +DV+ L + G + P GL + AHV G P Sbjct: 316 NLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHVMDENGYPIHRPGIA 375 Query: 233 GLDDALWAVISAMLAKNPADRPGMADLR 260 G++ A I+ +L + RP + R Sbjct: 376 GVETAYTRFITDILGVSADSRPDSNEAR 403
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.4 bits (232), Expect = 7e-24 Identities = 33/113 (29%), Positives = 59/113 (52%), Gaps = 1/113 (0%) Query: 17 GRILIVEDEPQLLRAMRINLHSRGHEVRTAVDGAHALREAASHPPDLVVLDLGLPDLDGI 76 IL+ +D+ + + L G++VR + A R A+ DLVV D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 77 DVIRGLR-GWTRVPIIVLSGRTSGHDKIAALDAGADDYVTKPFSVEELLARIR 128 D++ ++ +P++V+S + + I A + GA DY+ KPF + EL+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 26.6 bits (58), Expect = 0.010 Identities = 5/18 (27%), Positives = 10/18 (55%) Query: 23 GIVGGWAGDWLDSGTDGY 40 G++GGWA + ++ Sbjct: 374 GVIGGWAAEAIEKNPPCK 391
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 35.6 bits (82), Expect = 0.001 Identities = 31/140 (22%), Positives = 61/140 (43%), Gaps = 13/140 (9%) Query: 404 SLAFLAFAVPMGRLADRVGAGRVLLGGQVALGCCFAVLLAPAPRGWSVLALP-VLLGIYF 462 L F G+L+D++G R+LL G + + C +V+ +S+L + + G Sbjct: 59 MLTFSIGTAVYGKLSDQLGIKRLLLFG-IIINCFGSVIGFVGHSFFSLLIMARFIQGAGA 117 Query: 463 AASDGVIAALTSQTVPASARTTGLALVGVVLAAGRGTATLGFGAV-----WTRSGPDVAL 517 AA ++ + ++ +P R L+G ++A G G G + W+ L Sbjct: 118 AAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS------YL 171 Query: 518 ADALVLTLVSGTFAAVLLRP 537 ++T+++ F LL+ Sbjct: 172 LLIPMITIITVPFLMKLLKK 191
>BACSURFANTGN#Yersinia/Haemophilus virulence surface antigen signature. Length = 322 Score = 31.6 bits (71), Expect = 0.008 Identities = 12/25 (48%), Positives = 17/25 (68%) Query: 206 NAWGGYSLYHGPRGFADRARVVSFD 230 N++ G S+YH P G R RV++FD Sbjct: 294 NSFWGNSMYHYPLGVGQRFRVLTFD 318
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.3 bits (70), Expect = 0.013 Identities = 24/78 (30%), Positives = 32/78 (41%), Gaps = 5/78 (6%) Query: 160 DRRVLARQSLAMPGGRSPAAAADADAVPVAPNATDDPSPGRE---TPDPATPGPARGPGA 216 D +V+ R L +P A + P A N ++P+P P+P P P P A Sbjct: 306 DVQVIPRPDLTPGSAEAPNAQPLPEVSP-AENPANNPAPNENPGTRPNPE-PDPDLNPDA 363 Query: 217 APGADGSSRTRRRRRAEP 234 P DG TR A P Sbjct: 364 NPDTDGQPGTRPDSPAVP 381
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 28.7 bits (64), Expect = 0.001 Identities = 8/37 (21%), Positives = 17/37 (45%), Gaps = 2/37 (5%) Query: 28 VPG-HVLIRDSKNPGGGMLSFTEAEWAAFLVGARAGE 63 +PG HV++++ + L A AA+ ++ Sbjct: 499 IPGSHVIVKNIMDIPESTLLE-AANLAAYYSKSQNSS 534
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 30.0 bits (67), Expect = 0.018 Identities = 14/37 (37%), Positives = 19/37 (51%), Gaps = 1/37 (2%) Query: 9 LAAAAAAALACSAAATASASTTTAAST-TASTLTTAP 44 + +AAAAAL A A+A AA+T A + A Sbjct: 7 IVSAAAAALLAVAPIAATAMPVNAATTINADSAINAN 43 Score = 30.0 bits (67), Expect = 0.020 Identities = 17/43 (39%), Positives = 21/43 (48%), Gaps = 3/43 (6%) Query: 6 RTVLAAAAAAALACSAAATA---SASTTTAASTTASTLTTAPG 45 R V AAAAA AATA +A+TT A + + T A Sbjct: 6 RIVSAAAAALLAVAPIAATAMPVNAATTINADSAINANTNAKY 48
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.025 Identities = 12/31 (38%), Positives = 16/31 (51%), Gaps = 3/31 (9%) Query: 204 LLFGPPGTGKTSFARAI---AARLEWPFVEL 231 ++ G GTGK ARA+ R PFV + Sbjct: 164 MITGESGTGKELVARALHDYGKRRNGPFVAI 194
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.1 bits (68), Expect = 0.011 Identities = 27/136 (19%), Positives = 41/136 (30%), Gaps = 30/136 (22%) Query: 2 YLVTGATGNIGRELVDALAAAGQPVRALTRRGELPARPAPSASSPSPASSPSEESSTSRA 61 YLVTGA G IG + L AG V + + + ++ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDN----------LNDYYDVSLKQARLELLAQP 52 Query: 62 PLEVVRGDLDRPETLAGPL--------------AGVRGMFLLPG-YRDMP-----GVLAE 101 + + DL E + VR P Y D +L Sbjct: 53 GFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEG 112 Query: 102 ARRAGVEHVVLLSGSS 117 R ++H++ S SS Sbjct: 113 CRHNKIQHLLYASSSS 128
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.6 bits (144), Expect = 2e-13 Identities = 35/187 (18%), Positives = 62/187 (33%), Gaps = 9/187 (4%) Query: 2 AHELFYWQGIRATGVDTLAAQAGVAPTTLYRLFAAKDDLVAAYVERAGALYRQWFTEAAE 61 A LF QG+ +T + +A AGV +Y F K DL + E + + + E Sbjct: 20 ALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQA 79 Query: 62 AGGTSPRARILAVFDALVE--QTRPDRCRGCPFLMALAEIPDPQAPAHRHAVATKAWVRD 119 P + + + ++E T R + E A + D Sbjct: 80 KFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYD 139 Query: 120 QFAAMTAALAAPGADPTAPGADSTSDSRELADQLVLIMEGVYAS-VAALGADGPARHARD 178 + + +R A + + G+ + + A + + ARD Sbjct: 140 RIEQTLKHCIEAK------MLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARD 193 Query: 179 LVRILLD 185 V ILL+ Sbjct: 194 YVAILLE 200
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 32.4 bits (74), Expect = 0.002 Identities = 18/84 (21%), Positives = 31/84 (36%), Gaps = 13/84 (15%) Query: 70 LRAAAQAGPDAVVVPKIGSPADVHAVERDLDAAGA--------PGHTLIW-AMVETPIAM 120 LRA+ G V+ P I + ++ + + ++ MVE P Sbjct: 379 LRASTY-GNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTA 437 Query: 121 LRALEIAQASPRLAVLVMGTNDLA 144 + A A+ ++ GTNDL Sbjct: 438 VAANLFAKEVDFFSI---GTNDLI 458
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 38.4 bits (89), Expect = 1e-04 Identities = 42/161 (26%), Positives = 58/161 (36%), Gaps = 12/161 (7%) Query: 413 RDDCFGDKDGFGRDGRDGKDGFGKDGRDGKDG-FGNNGFGRDGFGRDGFGNRNISNDKVA 471 D FG K G DG D +G DG D +G+ G + G G+ + Sbjct: 728 ADKFFGSKFTDIFHGADGDDLI--EGNDGNDRLYGDKG---NDTLSGGNGDDQL--YGGD 780 Query: 472 RADELGGQNGWGGQNGWDGKNGWDGWDGKNGRDNKDGRDGRDNKDGRDGRDGWDNKDGRD 531 D+L G G NG DG + + ++ G G D G +G D D +G D Sbjct: 781 GNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDD 840 Query: 532 GRDGWDNKDGRDGKDGWGG----KDGRDDKDDWFDDKDDKD 568 G D G+G DG + D D +D Sbjct: 841 LLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRD 881 Score = 34.6 bits (79), Expect = 0.001 Identities = 27/84 (32%), Positives = 32/84 (38%), Gaps = 8/84 (9%) Query: 490 GKNGWDGWDGKNGRDNKDGRDGRDNKDGRDGRD---GWDNKDGRDGRDGWDNKDGRDGKD 546 G D + G D G DG D +G DG D G D G +G D G DG D Sbjct: 724 GTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGND 783 Query: 547 GWGGKDGRD-----DKDDWFDDKD 565 G G + D DD F + Sbjct: 784 KLIGVAGNNYLNGGDGDDEFQVQG 807 Score = 33.0 bits (75), Expect = 0.005 Identities = 35/126 (27%), Positives = 50/126 (39%), Gaps = 7/126 (5%) Query: 471 ARADELGGQNGWGGQNGWDGKNGWDGWDGKNGRDNKDGRDGRDNKDGRDGRDGWDNKDGR 530 RAD+ G +G DG + +G DG D G G D G +G D DG Sbjct: 726 TRADKFFGSKFTDIFHGADGDDLIEGNDGN---DRLYGDKGNDTLSGGNGDDQLYGGDGN 782 Query: 531 D---GRDGWDNKDGRDGKDGWGGKDGRDDKDDWFDDKDDKDRDRRDGGPCFVGAGVGVGV 587 D G G + +G DG D + + K+ F K + D+ G + G G + Sbjct: 783 DKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGN-DKLYGSEGADLLDGGEGDDL 841 Query: 588 VGAGVG 593 + G G Sbjct: 842 LKGGYG 847
>cloacin#Cloacin signature. Length = 551 Score = 32.8 bits (74), Expect = 0.005 Identities = 22/64 (34%), Positives = 22/64 (34%), Gaps = 3/64 (4%) Query: 625 GPGGAPGTGGAPGTGGAPGTGGALGTGGAPGI---GGSRSAGSSRGAGSADGDGADGGGS 681 GP G GGA G G G GI GGS S G G G S Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLS 82 Query: 682 AVAT 685 AVA Sbjct: 83 AVAA 86
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 77.9 bits (192), Expect = 1e-17 Identities = 59/301 (19%), Positives = 102/301 (33%), Gaps = 47/301 (15%) Query: 306 RVLVTGAGGSIGSELCRQIAGYRPAELIMLDR----DESALRAVQLSLTGRAMLDDDAIV 361 + LVTGA G IG + +++ +++ +D + +L+ +L L + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLE-AGHQVVGIDNLNDYYDVSLKQARLELLAQ---PGFQFH 57 Query: 362 LGDIRDLDLVTTLFMERRPQVVFHAAALKHLPLLERFPGESVKTNVWGTLAILRTAVACG 421 D+ D + +T LF + VF + + P +N+ G L IL Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 422 VERLVNIST---------------DKAANPVSALGYSKRITERLTAHLAREASG-TLVSV 465 ++ L+ S+ D +PVS +K+ E + AH G + Sbjct: 118 IQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELM-AHTYSHLYGLPATGL 176 Query: 466 RFGNVLGSNGS---VLTVFAGQLAAGGPITV-THPDVTRYFMTIPEAVQLVLQA------ 515 RF V G G L F + G I V + + R F I + + +++ Sbjct: 177 RFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH 236 Query: 516 ------------GALGAPGEALVLDMGEPVRIADVAARLAAREKRPIEIVYTGLGRGEKL 563 A AP + PV + D L + L G+ L Sbjct: 237 ADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVL 296 Query: 564 H 564 Sbjct: 297 E 297
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 175 bits (446), Expect = 5e-55 Identities = 72/281 (25%), Positives = 113/281 (40%), Gaps = 25/281 (8%) Query: 18 VKLVIGSVTDRSLVEE--ACTGAGSIVHLAARPSVERSLLDPMATHTVNATGTLTVLDVA 75 + + DR + + A + R +V SL +P A N TG L +L+ Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 76 QRAE-THVVVASSSSVYGGAGPLPRAEDAPT-LPRSPYAASKLAAEGYALAYQAGFGLPV 133 + + H++ ASSSSVYG +P + D P S YAA+K A E A Y +GLP Sbjct: 114 RHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPA 173 Query: 134 LAVRLFNVFGPYQSVGHAYAAVVPTFIEAALAGRPLTLHGDGRQTRDFTY----VAGVAG 189 +R F V+GP+ A F +A L G+ + ++ G+ RDFTY + Sbjct: 174 TGLRFFTVYGPWGRPDMAL----FKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 190 ML----CDAAVRRVSHPRP---------VNIAFGTRTDLLTVIGELERIVGRRLSVHHSA 236 + V P NI + +L+ I LE +G + Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP 289 Query: 237 PRTGDVRDSQADATTMRRLFPDATGLDLAASLEATVAWYAD 277 + GDV ++ AD + + + ++ V WY D Sbjct: 290 LQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>PERTACTIN#Pertactin signature. Length = 922 Score = 31.6 bits (71), Expect = 0.004 Identities = 19/57 (33%), Positives = 24/57 (42%) Query: 229 WPPDRPQPLDRPQPLDQPWPPDRPRPLDRPRPLDPPQPLDRPQPLDQLRPPGDHTGR 285 W + P+P QP P P+P P+P PPQP PQ + P GR Sbjct: 560 WSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGR 616
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.033 Identities = 15/35 (42%), Positives = 18/35 (51%), Gaps = 2/35 (5%) Query: 520 STPPAPARPVAGTDPPARPA--GAAATVPAGPGGG 552 S+P A A G +PP + A T P GPGGG Sbjct: 388 SSPTAAAGGAGGGEPPKKRDPSAGAGTDPGGPGGG 422
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 353 bits (907), Expect = e-122 Identities = 145/399 (36%), Positives = 218/399 (54%), Gaps = 36/399 (9%) Query: 1 MNVLVVNAGSASLKLRLVGPDDTLLAARDLDSPAGRADP-------GE------------ 41 M +LV+N GS+SLK +L+ D + A+ L G D GE Sbjct: 1 MKILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHK 60 Query: 42 --LAAALGELAGAAHG------EPVAVGHRIVHGGTEFTRPVVVDEAVAGRLRALTALAP 93 + L L + +G E AVGHR+VHGG FT V++ + V + LAP Sbjct: 61 DAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAP 120 Query: 94 LHQPAALDALDAVRAALPEADQVACFDTAFHSRLPAAAVTYALPATWRERYGIRRYGFHG 153 LH PA ++ + A +P+ VA FDTAFH +P A Y +P + +Y IR+YGFHG Sbjct: 121 LHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHG 180 Query: 154 LSHAHASRRAARLTGAR----RIVTCHLGSGASLAAVLDGVGVDTTMGFTPLEGLVMATR 209 SH + S+RAA + +I+TCHLG+G+S+AAV +G +DT+MGFTPLEGL M TR Sbjct: 181 TSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTR 240 Query: 210 SGSVDPGALLWLQTEAGVSAAELTDGLFRSSGLLGLAG-TADLRAVEAGA-AGGDPACAL 267 SGS+DP + +L + +SA E+ + L + SG+ G++G ++D R +E A GD L Sbjct: 241 SGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQL 300 Query: 268 ALDVYLHRLRAQIAAMTAALGGLDALVFTGGVGEGSATVRAGAAAGLGHLGVAVDPARNA 327 AL+V+ +R++ I + AA+GG+D +VFT G+GE +R GL LG +D +N Sbjct: 301 ALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNK 360 Query: 328 APADGTVDREIGPPEAPVRTLVLAAREDLEIARGVRDVL 366 + + I ++ V +V+ E+ IA+ ++ Sbjct: 361 VRGE---EAIISTADSKVNVMVVPTNEEYMIAKDTEKIV 396
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 172 bits (437), Expect = 5e-53 Identities = 87/336 (25%), Positives = 143/336 (42%), Gaps = 36/336 (10%) Query: 9 TVLVTGAAGFIGSHTCVDLLAAGHRVVGVDNFVNSSPRVL--DRLRKVADRDLEFVRLDV 66 LVTGAAGFIG H LL AGH+VVG+DN + L RL +A +F ++D+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 67 RDRAALGEVFRRQPIDAVIHFAALKAVGESVEMPLEYYDTNVNATLGLVGVMAEHGVHRL 126 DR + ++F + V AV S+E P Y D+N+ L ++ + + L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 127 VFSSSCSIYGTVDTVPITEDTPA-RPTNPYSRTKWMCEQILADVCARDPAWQVISLRYFN 185 +++SS S+YG +P + D P + Y+ TK E ++A + LR+F Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE-LMAHTYSHLYGLPATGLRFFT 180 Query: 186 PVGAHESGLLGEDPRGVPNNVMPYLAQVAVGRRAELSVFGDDYPTPDGTGVRDYIHVVDL 245 G P G P+ + + + ++ + V+ G RD+ ++ D+ Sbjct: 181 VYG----------PWGRPDMALFKFTKAMLEGKS-IDVYN------YGKMKRDFTYIDDI 223 Query: 246 AEGHRLALDHLADQSG---------------HRVVNLGTGAGTSVRELHAAFSAACGRDL 290 AE D + +RV N+G + + + A A G + Sbjct: 224 AEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEA 283 Query: 291 PYRVVARRPGDVAALVADATLAREALGWTARRSVAD 326 ++ +PGDV AD E +G+T +V D Sbjct: 284 KKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKD 319
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 36.1 bits (83), Expect = 3e-04 Identities = 15/96 (15%), Positives = 25/96 (26%), Gaps = 2/96 (2%) Query: 256 ASPTVSPGPDAVGSPTPSATTQPSPAVGVTTPPSPTASPSAAEGRGGRRPFGAASPSASA 315 P P+ P P + + P + +R + Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRD--VKPVESRP 125 Query: 316 ASPSAAGLPTVPPASPGTTTGATAAATPATGGAPEI 351 ASP P P +S T + + A+G Sbjct: 126 ASPFENTAPARPTSSTATAATSKPVTSVASGPRALS 161
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.023 Identities = 37/127 (29%), Positives = 43/127 (33%), Gaps = 16/127 (12%) Query: 1120 GAGMSGAGGSAQAWHGRFAPGAPVPVVPGGVAPPGPGPGPGQPVVPDGAGGSDGRGGGGA 1179 G G+ G W P GG G G G G GG Sbjct: 26 GLGVGGGASDGSGWSSENNPW-------GG----GSGSGIHWGGGSGHGNGGGNGNSGGG 74 Query: 1180 PGAPGVPGVPGVPGAPGVPGASAVPGPSGGPATPVAAGGPGVPAAAGAADGPAQTGPVPL 1239 G G P A G P A + PG +GG A ++AG +AA A A GP Sbjct: 75 SGTGGNLSAVAAPVAFGFP-ALSTPG-AGGLAVSISAGA---LSAAIADIMAALKGPFKF 129 Query: 1240 GSQGGAL 1246 G G AL Sbjct: 130 GLWGVAL 136
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 94.1 bits (234), Expect = 4e-23 Identities = 82/372 (22%), Positives = 133/372 (35%), Gaps = 66/372 (17%) Query: 2 FGIDLGTTYSCIAQVDEYGRPDVIRNIESQPTTPSVVLFDGGGEGATSFV--VGTQAKRQ 59 IDLGT + I G+ V+ PSVV G+ V VG AK+ Sbjct: 13 LSIDLGTANTLIYVK---GQGIVLNE-------PSVVAIRQDRAGSPKSVAAVGHDAKQM 62 Query: 60 ARIRPDDVARLVKRHMGASDWRFVAHDVEYSASAVSSLVLKALAADAERATGTPVTDAVI 119 P ++A + G V D + + + + + P ++ Sbjct: 63 LGRTPGNIAAIRPMKDG------VIADFFVTEKMLQHFIKQV----HSNSFMRPSPRVLV 112 Query: 120 TVPAYFGDEERKATKLAGELAGLNVVDIINEPTAAAFAYGFGQDGAEESTVLVYDLGGGT 179 VP ER+A + + + AG V +I EP AAA G E + +V D+GGGT Sbjct: 113 CVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVS--EATGSMVVDIGGGT 170 Query: 180 FDTTVIRLSEGAITVVATDGDHELGGADWDNELVRYLAQKFT-----EAQPDAGDPLDDV 234 + VI L + +GG +D ++ Y+ + + + Sbjct: 171 TEVAVISL--NGVV---YSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSA 225 Query: 235 YDEQELLTAAEDAKLALSGRDSVDVLVVHKGRRVSVPVTRATFEEITGPLLRRTLDLTGS 294 Y E+ ++ + GR+ L R ++ + E + P L + Sbjct: 226 YPGDEVR------EIEVRGRN----LAEGVPRGFTLN-SNEILEALQEP-LTGIVSAVMV 273 Query: 295 VLERA--------REKGVEKIDLCLLVGGMSKTPAVGRRLQESFGL-TSRLVDPDLAVAK 345 LE+ E+G+ +L GG + + R L E G+ DP VA+ Sbjct: 274 ALEQCPPELASDISERGM------VLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVAR 327 Query: 346 GAAVYGQKKALE 357 G KALE Sbjct: 328 GGG-----KALE 334
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 31.2 bits (70), Expect = 0.022 Identities = 19/65 (29%), Positives = 25/65 (38%) Query: 51 LAPDPPASDPLALDPLAPDPTDAELPDPELPDPRLLEPESPRPDPSHADPLAGVGEPGRD 110 LA + L P P A P P+ P P +PE+P P P L+ + Sbjct: 556 LAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVN 615 Query: 111 PLGVG 115 GVG Sbjct: 616 TGGVG 620
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 28.3 bits (63), Expect = 0.023 Identities = 20/91 (21%), Positives = 33/91 (36%), Gaps = 15/91 (16%) Query: 109 VSIYDADSRQQNFGQVRNAFIRIVNGAGGTEIARYDLT------EDASTETAMVFGEVYR 162 V+I +AD Q F V + + ++ G RY +T +A E F Sbjct: 346 VTIKEADGSTQIF-TVPYSSVPLLQREG---HTRYSITAGEYRSGNAQQEKPRFFQSTLL 401 Query: 163 HGSDWKFRA-----VGQGYASGLAGIARDYG 188 HG + + Y + GI ++ G Sbjct: 402 HGLPAGWTIYGGTQLADRYRAFNFGIGKNMG 432
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 26.0 bits (56), Expect = 0.038 Identities = 7/15 (46%), Positives = 9/15 (60%) Query: 104 HLDLPAQPGPPGPGG 118 L+ P +P PG GG Sbjct: 48 GLEYPVRPPVPGAGG 62
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.048 Identities = 38/206 (18%), Positives = 69/206 (33%), Gaps = 50/206 (24%) Query: 12 RPVRTELRDNLVALMKGDTPRFPGIVGFDETVLPQVERAILAGHDIVFLGERGQGKTRLI 71 RP + E + G + + + + R + ++ GE G GK + Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAM-------QEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 72 RTLVNLLDEWSPAVAGCEINDHPYVPVCGRCRALAAELGEDLPIAWRHRSDRFGEKLATP 131 R L + + P+V + A+ +L E S+ FG + Sbjct: 178 RALHDYGKRR----------NGPFVAI--NMAAIPRDLIE---------SELFGHEKGAF 216 Query: 132 DTSVGDLIGDVDPVKVAEGRTLGDPETVHYGLVPRTNRGIFSVNELPDLAERIQVSLLNV 191 + G + AEG TL ++E+ D+ Q LL V Sbjct: 217 TGAQTRSTGRFE---QAEGGTL-------------------FLDEIGDMPMDAQTRLLRV 254 Query: 192 LEERDIQVRGYLLRLPLDLLLVASAN 217 L++ + G + D+ +VA+ N Sbjct: 255 LQQGEYTTVGGRTPIRSDVRIVAATN 280
>PF05844#YopD protein Length = 295 Score = 27.7 bits (61), Expect = 0.041 Identities = 20/63 (31%), Positives = 23/63 (36%), Gaps = 3/63 (4%) Query: 171 LAADPALTPTAPAPPPTPAPPTSTPTAAPTRPARDVPGGSAGDAVASPGPQVVTDDVAAE 230 LAA A P+ P P TP AA P + D V P+ V D V E Sbjct: 8 LAATQAAIPSEPIAPGAAGRSVGTPQAAAELPQV---PAARADRVELNAPRQVLDPVRME 64 Query: 231 GGG 233 G Sbjct: 65 AAG 67
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 40.0 bits (93), Expect = 1e-05 Identities = 30/170 (17%), Positives = 46/170 (27%), Gaps = 24/170 (14%) Query: 193 TTGRLFTTIGGADFACSASVVTSPGHDLVVTAGHCLHGGARAQFARRVAFVPGYTDGTMP 252 + F S VV G D ++T H + AF P Sbjct: 89 PVTYIQVEAPTGTFIASGVVV---GKDTLLTNKHVVD-ATHGDPHALKAFPSAINQDNYP 144 Query: 253 YGIWTARRLTVTPGWAGGSNFDVDAGFALFNTHGGQHIENVVGGQGIA------FGLPST 306 G +TA ++T G + +HI VV ++ T Sbjct: 145 NGGFTAEQITKYSGEGDLAIVKFSP------NEQNKHIGEVVKPATMSNNAETQVNQNIT 198 Query: 307 SAQYSFGYPRLSPYDGSQLIYCGGPGSVDRYGGPSIGVHCRMTAGASGGP 356 Y P + ++ I G ++ T G SG P Sbjct: 199 VTGYPGDKPVATMWESKGKITY--------LKGEAMQYDLSTTGGNSGSP 240
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.8 bits (72), Expect = 0.008 Identities = 19/91 (20%), Positives = 38/91 (41%), Gaps = 3/91 (3%) Query: 104 IVVFVIMLPIYLKTKNPVEAWQAGLAWAFIIGIIVVIGAFV-GPMIRKYAPRAAMLGTLA 162 + FV M+P +K + + + G F + V+I ++ G ++ + P + + Sbjct: 272 VAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVT 331 Query: 163 GISIAF--ISMRPAAQMWDAAWIALPVFGLL 191 +S++F S W I + V G L Sbjct: 332 FLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 67.7 bits (165), Expect = 2e-15 Identities = 45/195 (23%), Positives = 77/195 (39%), Gaps = 19/195 (9%) Query: 7 DFTFDPATTALVVIDMQRDFLEPGGFGESLGNDVSQLRSTIEPLQAVLAAVRAAGLTVIH 66 + DP L++ DMQ F++ S + ++ + G+ V++ Sbjct: 23 SWVPDPNRAVLLIHDMQNYFVDA------FTAGASPVTELSANIRKLKNQCVQLGIPVVY 76 Query: 67 TREGHLPDLSDLPPAKLHRGDAALRIGDLGPKGRILIRGEYGQDIIDELAPVDGEYVIDK 126 T + P + D AL GP L G Y + II ELAP D + V+ K Sbjct: 77 TAQ----------PGSQNPDDRALLTDFWGPG---LNSGPYEEKIITELAPEDDDLVLTK 123 Query: 127 PGKGAFYATAFGDVLAEKGITSLVVAGVTTEVCVHTTVREANDRGFECLVLSDCVGSYFP 186 AF T +++ ++G L++ G+ + T EA + + D V + Sbjct: 124 WRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183 Query: 187 EFQRVALEMVAAQGG 201 E ++ALE A + Sbjct: 184 EKHQMALEYAAGRCA 198
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 48.1 bits (114), Expect = 2e-07 Identities = 41/238 (17%), Positives = 73/238 (30%), Gaps = 24/238 (10%) Query: 304 EDAVEAVPATARETT-VTVAAPPVAAPPVAAP---PVAAPPVAAPPVAAPPVDEHPRPPA 359 V+ T V + P +A PV P A P V E+ + + Sbjct: 989 NQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQES 1048 Query: 360 APEAEPVARPEVEAEPDAR-AAAGAEADARSEVEPGALPESGVESEAQTEVAAESGAKSE 418 + E R A A+++ ++ + + +SG E++ + A E Sbjct: 1049 KTVEKNEQDAT-ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE 1107 Query: 419 AQPESGVEPGARPEAAAEPEPTSPSAATVAGPTSLSPPVGSGRPAGDGTAVRAVAATVLI 478 + ++ VE + P+ TS + ++ P R TV I Sbjct: 1108 KEEKAKVE---TEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN---------DPTVNI 1155 Query: 479 PQQALPAPSPPTRQAATVRPARTGEVPLAARPAEAEGSPRQGDDVVTETARSGESVAT 536 + S A T +PA+ E E + + V E + T Sbjct: 1156 KE----PQSQTNTTADTEQPAK--ETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.4 bits (188), Expect = 2e-18 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 3/110 (2%) Query: 20 PRSKILLVDDRADNLMALEAILASLDQDLVTASSGEEALKRLLVDDFAVILLDVQMPGMD 79 + IL+ DD A L L+ D+ S+ + + D +++ DV MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 80 GFETAHRIKQRGRTRDTPIIFLTAIDREPHHAFRGYAVGAVDYIAKPFDP 129 F+ RIK+ D P++ ++A + A + GA DY+ KPFD Sbjct: 62 AFDLLPRIKKAR--PDLPVLVMSAQN-TFMTAIKASEKGAYDYLPKPFDL 108
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-16 Identities = 37/118 (31%), Positives = 54/118 (45%), Gaps = 4/118 (3%) Query: 1250 GTTVLVVDDDVRNVFALTSALEMYGMRVLYADNGHDAIRTLQQDTAPVHLVLMDVMLPGM 1309 G T+LV DDD L AL G V N R + LV+ DV++P Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG--DGDLVVTDVVMPDE 60 Query: 1310 DGNETTSMIRDMPAFADLPILVLTAKAMPGDREKSITAGATDYITKPVDLDHLLGVMR 1367 + + I+ DLP+LV++A+ K+ GA DY+ KP DL L+G++ Sbjct: 61 NAFDLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.039 Identities = 26/120 (21%), Positives = 38/120 (31%), Gaps = 7/120 (5%) Query: 149 TAGDGEATATASRDGDRTPASA----AAADPAASAQVATRPLPAEERRDGPASPSTPPPS 204 T AT T + + AA+ + P + P P P Sbjct: 530 TPLGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPP 589 Query: 205 TPPPSTLAPSTPPPDRAAPPAAPRAALVPSGLRADTPTAIPTTSTASA-TSQRRSRPGSG 263 P P AP PP R AA AA+ G+ + ++ S + R P +G Sbjct: 590 QPQPEAPAPQ-PPAGRELSAAA-NAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAG 647
>PF04183#IucA / IucC family Length = 580 Score = 227 bits (581), Expect = 2e-68 Identities = 109/520 (20%), Positives = 166/520 (31%), Gaps = 76/520 (14%) Query: 80 VDAGLLAALLVREITAEQGMPAAQGAEALARILDSACRIAAHLDARRTRGHPSAIPPFLA 139 D +LA L+ ++ M A AE + + + L ARR I Sbjct: 68 ADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNAD 127 Query: 140 AEQASLTGHPFHPAAASRQGASDRAMAAYSPERAGSFALHWFAAHPSVVATSGAPAAGRG 199 Q L+GHP R+G A+ Y+PE A +F LHW A + Sbjct: 128 RLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCD------ 181 Query: 200 PTATSAVGRPPVTRLLTELYGGDGALGAAAGYRPIGAGPSAPTGADLDGQPDRRVPPGYV 259 + +LLT + A + + ++ Sbjct: 182 -------NEMDIHQLLTA---------------AMDPQEFARFSQVWQ---ENGLDHNWL 216 Query: 260 PVPAHPWQARELTERADSPLARLLADGRLVDLGRSGRPWYPTSSLRTVWRPDRKVML--K 317 P+P HPWQ ++ + A+GR+V LG G W SLRT+ R+ L K Sbjct: 217 PLPVHPWQWQQKI---ATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIK 273 Query: 318 LSLGLRITNSRRVLHLGELRLAEMITRLVDAGLGAALTARHPDFHLIGEPDWVAVTRPGR 377 L L + T+ R + + + +R + T ++GEP V+ G Sbjct: 274 LPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGY 333 Query: 378 HPPSGGSEQPGIPRTTGTLGATTDGSDGTVGLETAIRTNPF---GPTDRAVSLAALIAPR 434 L R NP P + V +A L+ Sbjct: 334 ------------------AALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLM--- 372 Query: 435 PDRAADSRGRSRAAMLPRLLTRLADRRGESVQELAETWFGRYLAVLAAPVLDLYLRFGVG 494 D + L DR G AETW + V+ P+ L R+GV Sbjct: 373 ---ECDENNQP-------LAGAYIDRSGLD----AETWLTQLFRVVVVPLYHLLCRYGVA 418 Query: 495 VEAHLQNTLVSLDSDGWPVAGWYRDSQGYYVAASAAAAMERLLPGFATDLDAIFDDDLVA 554 + AH QN +++ +G P +D QG LP D+ + D + Sbjct: 419 LIAHGQNITLAMK-EGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLI 477 Query: 555 ERIIYYLFVNNVFAVAGALGAADVADEHLLLGRARDLLSR 594 + FV V L E +LS Sbjct: 478 HDLQTGHFV-TVLRFISPLMVRLGVPERRFYQLLAAVLSD 516
>PF04183#IucA / IucC family Length = 580 Score = 491 bits (1266), Expect = e-169 Identities = 201/666 (30%), Positives = 287/666 (43%), Gaps = 102/666 (15%) Query: 24 WRQAGRALLTKLIAELAYEDLLRPQIEDDAGGPDLAEHPPIGRGPLLAHQLVTAGAVYRF 83 W R L+ K+++EL YE + + + G D + + GA +RF Sbjct: 6 WDLVNRRLVAKMLSELEYEQVFHAESQ----GDD-------------RYCINLPGAQWRF 48 Query: 84 RARRGTFGSWWIDPASLTRTAPPVGGQGPLLSPPSGPEDHRPVDPHGQARSGAAAADDPV 143 A RG +G WID +L PV Sbjct: 49 IAERGIWGWLWIDAQTLRCADEPV---------------------------------LAQ 75 Query: 144 RFLRDAQPLLGWPDPVVADVVRDLLATQSADQCLLAT--ASPAASLAGLSFVALEGHQSG 201 L + +L D VA+ ++DL AT D LL A+ L L+ L+ SG Sbjct: 76 TLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNADRLQCLLSG 135 Query: 202 HPCLVANKGRLGFG-AAASRFTPEARSPFRLRWVAAHPTIGRCWDIASTGPDHPDESTMD 260 HP V NKGR G+G A R+ PE + FRL W+A +H + Sbjct: 136 HPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKR-------------EHMIWRCDN 182 Query: 261 RSGNAALVRAELDSATRAQFADVLGRALVAAAPPGDAPARASQPPSPTAPPTAAEDYVWL 320 L+ A +D A+F+ V + +++ L Sbjct: 183 EMDIHQLLTAAMDPQEFARFSQVWQENGLD------------------------HNWLPL 218 Query: 321 PVHPWQWENVIVPLFAAELATGLLVPLGEGPDRYLPLQAVRTLANIDRPERRNVKLALMI 380 PVHPWQW+ I F A+ A G +V LGE D++L Q++RTL N R ++KL L I Sbjct: 219 PVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTI 278 Query: 381 RNTLVWRGMSAADAAAGPAVSRWLLDLRDADPFLREVTGVLPLPEVAGAAVGHGVYDAIP 440 NT +RG+ AAGP SRWL + D L + +G + L E A V H Y A+ Sbjct: 279 YNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQ-SGAVILGEPAAGYVSHEGYAALA 337 Query: 441 GAPYRLHELLGVIWRDPVERHLVDGEQARSLASLLTIGSDGRSLTAELVARSGQSAHDWL 500 APYR E+LGVIWR+ R L E +A+L+ + + L + RSG A WL Sbjct: 338 RAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWL 397 Query: 501 AALFAALLPPLLHYLYRYGVAFTPHGENIICIFDAEQRPRRIAVKDFGADIELVDGDFPE 560 LF ++ PL H L RYGVA HG+NI E P+R+ +KDF D+ LV +FPE Sbjct: 398 TQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMK-EGVPQRVLLKDFQGDMRLVKEEFPE 456 Query: 561 RAGMPAQAAAYCRRWPGPLLAHSVLSAVFAGHFRYFSVLAADHLQVEEGEFWRLVRAAVD 620 +P + R L H + + F R+ S L L V E F++L+ A + Sbjct: 457 MDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPL-MVRLGVPERRFYQLLAAVLS 515 Query: 621 GYHARFPQLRDRFREIDLLTPRFDRVCLNREQLAGAGFHDRADRDGGFDLMH---GEVAN 677 Y + PQ+ +RF L P+ RV LN +L D DGG ++ ++ N Sbjct: 516 DYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLT------WPDLDGGSRMLPNYLEDLQN 569 Query: 678 PVATIT 683 P+ +T Sbjct: 570 PLWLVT 575
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 41.0 bits (96), Expect = 2e-05 Identities = 44/237 (18%), Positives = 85/237 (35%), Gaps = 23/237 (9%) Query: 124 VVSYWTGGGSALRSRDG-RSALVVASVRDDDEASDIVDRYESRREWSDTVTVLPGGAATV 182 S+W G L +G S + + D + E + + LP G + Sbjct: 804 TTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALME------NLASKLPAG---I 854 Query: 183 GEDIGSQVS------SDLAVAESIAIPVTLVLLVLAFAGVVAALLPLGIGLLGIVGGFAA 236 G D + +I+ V + L + + + + LGIVG A Sbjct: 855 GYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA 914 Query: 237 LSVIGGLTDVSIFAVNLATAMGLGLGIDYSLLMVSRFREELAA-GRDRADAVAVTVHSAG 295 ++ DV F V L T + GL ++L+V ++ + G+ +A + V Sbjct: 915 ATLFNQKNDV-YFMVGLLTTI--GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRL 971 Query: 296 RTILFSGATVIVALAVMLLFP---PFFLKSMAYAGIAVTLVAVVAAIVSLPALLMVL 349 R IL + I+ + + + ++ + + A + AI +P +V+ Sbjct: 972 RPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 5e-08 Identities = 29/170 (17%), Positives = 61/170 (35%), Gaps = 4/170 (2%) Query: 1 MSSPVPRRERLRRATLDEIKQTAHAQLAELGPAALSLRGVARAMGMAPSALYRYVDSREV 60 M+ + + R I A ++ G ++ SL +A+A G+ A+Y + + Sbjct: 1 MARKTKQEAQETR---QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSD 57 Query: 61 LLAELTADGFASLADALEAAFTAGDPHDHLGRWLDVARAHRRWALDHTVEYTLLFGTRVP 120 L +E+ +++ LE + A P D L ++ + L+ Sbjct: 58 LFSEIWELSESNIG-ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK 116 Query: 121 EGGFVSVRVAAELQRSVAVLFRCMTEAIEAGLVDTGHLDAELTPTMQARL 170 + V + QR++ + E ++ L A+L A + Sbjct: 117 CEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAII 166
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 33.7 bits (76), Expect = 0.004 Identities = 19/65 (29%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 661 PAVDPFGSVPSPLVPSPPAPAPLAPAPVLATAANPDGTPTVLAEPAAVAAAASAVATAVA 720 P DP + P+ P P L A + G A+ AAVA A ++AT V Sbjct: 41 PNADPALGLEYPVRPPVPGAGGLN-ASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVN 99 Query: 721 AVLVA 725 +V + Sbjct: 100 SVAIG 104