PredictBias

		>BLACTAMASEA#Beta-lactamase class A signature.

		          Length = 286

		

		 Score = 54.8 bits (132), Expect = 9e-11

		 Identities = 22/97 (22%), Positives = 41/97 (42%), Gaps = 12/97 (12%)

		

		Query: 102 NEQFSMNDTQPMTAGSTYKLPLNMLVMDEVNRGKLSLTERFDINNTEY-EYQGEHDKYVA 160

		           +E+F M         ST+K+ L   V+  V+ G   L  +      +  +Y    +K++ 

		Sbjct: 59  DERFPMM--------STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHL- 109

		

		Query: 161 SFGGAMTIPEMQEYSLVYSENTPAYALAERLGGMEKF 197

		                MT+ E+   ++  S+N+ A  L   +GG    

		Sbjct: 110 --ADGMTVGELCAAAITMSDNSAANLLLATVGGPAGL 144

		

		

		>HELNAPAPROT#Helicobacter neutrophil-activating protein A family

		           signature.

		          Length = 153

		

		 Score =  146 bits (369), Expect = 2e-47

		 Identities = 47/147 (31%), Positives = 85/147 (57%), Gaps = 2/147 (1%)

		

		Query: 21  TNTKTKAVLNQAVADLSVAASIVHQVHWYMRGPGFLYLHPKMDELMDSLNSHLDKISERL 80

		             T  +  LN  +++  +  S +H+ HWY++GP F  LH K +EL D     +D I+ERL

		Sbjct: 9   NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERL 68

		

		Query: 81  ITIGGEPYSTLVEFSSNSGLTETTGTFDQPMSDRIQLLVDIYKYLSVLFQVGLDITDEEG 140

		           + IGG+P +T+ E++ ++ +T+     +   S+ +Q LV+ YK +S   +  + + +E  

		Sbjct: 69  LAIGGQPVATVKEYTEHASITDGGN--ETSASEMVQALVNDYKQISSESKFVIGLAEENQ 126

		

		Query: 141 DVPSNDIFTDAKSEIDKTIWMLTAELG 167

		           D  + D+F     E++K +WML++ LG

		Sbjct: 127 DNATADLFVGLIEEVEKQVWMLSSYLG 153

		

		

		>PF03309#Bvg accessory factor

		          Length = 271

		

		 Score = 34.4 bits (79), Expect = 5e-04

		 Identities = 37/165 (22%), Positives = 52/165 (31%), Gaps = 29/165 (17%)

		

		Query: 5   LLGIDLGGTTVKFGILTADGEVQE---KWAIETNTFENGSHIVPDIVESLKHRLELYGLT 61

		           LL ID+  T    G+++  G+  +   +W I T        +  D +        L G  

		Sbjct: 2   LLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTE-----PEVTADELALTIDG--LIGDD 54

		

		Query: 62  AEDFIGIGMGSPGAVDRENKTVTGAFNLNWAETQEVGSVIEKELGIPFAIDNDANVAALG 121

		           AE   G    S   V      V       W     V        GIP  +DN   V A  

		Sbjct: 55  AERLTGASGLS--TVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGA-- 110

		

		Query: 122 ERWVGAGAN----NRNVVFITLGTGVG-----------GGVIADG 151

		           +R V   A         + +  G+ +            GG IA G

		Sbjct: 111 DRIVNCLAAYHKYGTAAIVVDFGSSICVDVVSAKGEFLGGAIAPG 155

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score =  185 bits (471), Expect = 8e-53

		 Identities = 103/470 (21%), Positives = 191/470 (40%), Gaps = 84/470 (17%)

		

		Query: 8   IRNVAIIAHVDHGKTTLVDELLKQSHTLDERMELDE--RALDSNDLEKERGITILAKNTA 65

		           I N+ ++AHVD GKTTL + LL  S  + E   +D+     D+  LE++RGITI    T+

		Sbjct: 3   IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62

		

		Query: 66  VAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLT 125

		             +  T++NI+DTPGH DF  EV R + ++DG +L++ A +G   QTR +     +  + 

		Sbjct: 63  FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122

		

		Query: 126 PIVVVNKIDKPSARPEEVVDEVLELF---------IELG-------------------AD 157

		            I  +NKID+       V  ++ E           +EL                     +

		Sbjct: 123 TIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGN 182

		

		Query: 158 DDQLE--------------------------FPVVYASAINGTSSLSDNPADQEHTMAPI 191

		           DD LE                          FPV + SA N               +  +

		Sbjct: 183 DDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIG------------IDNL 230

		

		Query: 192 FDTIIDHIPAPVDNSDEPLQFQVSLLDYNDFVGRIGIGRIFRGTVKVGDQVTLSKLDGTT 251

		            + I +   +        L  +V  ++Y++   R+   R++ G + + D V +S      

		Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS----EK 286

		

		Query: 252 KNFRVTKLFGFFGLERREIEEAKAGDLIAISGMEDIFVGETITPTDAVEPLPALHIDEPT 311

		           +  ++T+++     E  +I++A +G+++ +   E + +   +  T  +     +    P 

		Sbjct: 287 EKIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345

		

		Query: 312 LQMTFLANNSPFAGREGKHVTSRKVEERLLAELQTDVSLRVEPTDSPDKWTVSGRGELHL 371

		           LQ T   +                + + LL    +D  LR     +  +  +S  G++ +

		Sbjct: 346 LQTTVEPSKPQQRE---------MLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQM 396

		

		Query: 372 SILIETMRRE-GYELQVSRPEVIIKEIDGVKCEPFERVQIDTPEEYQGSI 420

		            +    ++ +   E+++  P VI  E    K E    +++  P  +  SI

		Sbjct: 397 EVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP-PNPFWASI 445

		

		

		

		 Score = 39.5 bits (92), Expect = 4e-05

		 Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 1/79 (1%)

		

		Query: 403 EPFERVQIDTPEEYQGSIIQALSERKGDMLDMQMVGNGQTRLIFLVPARGLIGFSTEFLS 462

		           EP+   +I  P+EY         +   +++D Q + N +  L   +PAR +  + ++   

		Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCIQEYRSDLTF 595

		

		Query: 463 MTRGYGIMNHTFDQYLPVV 481

		            T G  +       Y    

		Sbjct: 596 FTNGRSVCLTELKGYHVTT 614

		

		

		>PF05932#Tir chaperone protein (CesT)

		          Length = 127

		

		 Score = 30.2 bits (68), Expect = 0.006

		 Identities = 10/24 (41%), Positives = 15/24 (62%)

		

		Query: 309 ELSWETLKHELEQLVEHAETYKEA 332

		           +LS  TLK E+  L+E    ++EA

		Sbjct: 102 KLSVPTLKREMAGLLEWMRGWREA 125

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score = 49.4 bits (118), Expect = 1e-08

		 Identities = 39/196 (19%), Positives = 79/196 (40%), Gaps = 18/196 (9%)

		

		Query: 169 IRKTVERAGIQVENIVISPLAMTRAVLNEGEREFGATVIDMGGGQTTVATMRAQELQFTN 228

		           IR++ + AG +   ++  P+A             G+ V+D+GGG T VA +    + +++

		Sbjct: 126 IRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSS 185

		

		Query: 229 IYPEGGEYITKDISKVLK------TSMQIAEALKFNFGNADIEEASETETVQVEVVGENS 282

		               GG+   + I   ++           AE +K   G+A   +      V+   + E  

		Sbjct: 186 SVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245

		

		Query: 283 P--VEITEKYLAEIISARVKHILDRVKQDLTR------GRLLDLPGGIVLVGGTAIMPGV 334

		           P    +    + E +   +  I+  V   L +        + +   G+VL GG A++  +

		Sbjct: 246 PRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISE--RGMVLTGGGALLRNL 303

		

		Query: 335 VEVAQEIFETNVKLYI 350

		             +  E  ET + + +

		Sbjct: 304 DRLLME--ETGIPVVV 317

		

		

		>ALARACEMASE#Alanine racemase signature.

		          Length = 356

		

		 Score = 29.0 bits (65), Expect = 0.013

		 Identities = 12/60 (20%), Positives = 26/60 (43%), Gaps = 5/60 (8%)

		

		Query: 132 GFSPEELDTVLNQIKNLDKICIVGLMT-MAPIDANTQELDKIFAETNELRQSIQDKKLKN 190

		           GF P+ + TV  Q++ +  +  + LM+  A  +      D I      + Q+ +  + + 

		Sbjct: 132 GFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAE----HPDGISGAMARIEQAAEGLECRR 187

		

		

		>adhesinb#Adhesin B signature.

		          Length = 310

		

		 Score =  213 bits (545), Expect = 2e-67

		 Identities = 78/317 (24%), Positives = 141/317 (44%), Gaps = 20/317 (6%)

		

		Query: 1   MKKKRIFGLAGLAAVVLAAGVGIYYTTSQHDSKGNGDLKVVTSFYPVYEFTKQVVGDEGE 60

		           MKK R   L  LA V LAA      +       G+  L VV +   + + TK + GD+  

		Sbjct: 1   MKKCRFLVLLLLAFVGLAA----CSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKIN 56

		

		Query: 61  VSYLIPAGSEVHDFQPSTKNVADIEKADTFVYLNENMET----WVPKVEKNINTKHTK-V 115

		           +  ++P G + H+++P  ++V    +AD   Y   N+ET    W  K+ +N   K  K  

		Sbjct: 57  LHSIVPVGQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDY 116

		

		Query: 116 IKASKGMILLPGTEEEDHDHGGEEHYHEYDPHVWLSPKRSQKLVKTIRDGLIAQHPDKKA 175

		              S+G+        +     G+    + DPH WL+ +      + I   L  + P  K 

		Sbjct: 117 YAVSEGV--------DVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKE 168

		

		Query: 176 VFTTNAEKYLKKLQALDKEYTEAFSQ--AKQKSFVTQHSAFAYLALDYGLTQVPISGVSA 233

		            +  N + Y++KL ALDKE  E F+    ++K  VT    F Y +  Y +    I  ++ 

		Sbjct: 169 TYEKNLKAYVEKLSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINT 228

		

		Query: 234 ESDPSAKRIASLSKYVSEYDIKYIYFEENASSSIAKTLANEVGVKTAVLNPIESLTTDQL 293

		           E + +  +I +L + + +  +  ++ E +      KT++ +  +        +S+     

		Sbjct: 229 EEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKG- 287

		

		Query: 294 KKGEDYVSVMTENLKSL 310

		           ++G+ Y S+M  NL+ +

		Sbjct: 288 EEGDSYYSMMKYNLEKI 304

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 59.3 bits (143), Expect = 3e-13

		 Identities = 30/192 (15%), Positives = 72/192 (37%), Gaps = 23/192 (11%)

		

		Query: 6   RRITKTRKAIYQAFLYLLNQKDYEAITVQEIIDLADVGRSTFYSHYESKELLLDELCQKL 65

		           +   +TR+ I    L L +Q+   + ++ EI   A V R   Y H++ K  L  E+ +  

		Sbjct: 7   QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66

		

		Query: 66  FHHLFERTQYLSPQ----------DYLAHIFQ---HFKKNQDHVTSLLLSKNDY----FI 108

		             ++ E       +          + L H+ +     ++ +  +  +            +

		Sbjct: 67  ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVV 126

		

		Query: 109 RQLRKELEHDVYPMVADEL---IQS---HPNIPHSYLKHLVITNFIETLTWWLKKGKSYS 162

		           +Q ++ L  + Y  +   L   I++     ++       ++       +  WL   +S+ 

		Sbjct: 127 QQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFD 186

		

		Query: 163 EQEVVQFYLEIL 174

		            ++  + Y+ IL

		Sbjct: 187 LKKEARDYVAIL 198

		

		

		>BICOMPNTOXIN#Staphylococcal bi-component toxin signature.

		          Length = 315

		

		 Score = 24.5 bits (53), Expect = 0.050

		 Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 1/54 (1%)

		

		Query: 1  MKKKTIVATTLSTLLVSTAILANAVKADEVETSTVITAPSTEVVTTEATTDMTS 54

		          M K  I+ TTLS  L+   +    ++  +    T      +++   + T D TS

		Sbjct: 1  MLKNKILTTTLSVSLL-APLANPLLENAKAANDTEDIGKGSDIEIIKRTEDKTS 53

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 37.2 bits (86), Expect = 9e-06

		 Identities = 25/145 (17%), Positives = 58/145 (40%), Gaps = 19/145 (13%)

		

		Query: 3   VVIRKVLPEEVEELKVISEDTFRETFAHDNTESQLQAYFDTALSEEVLLDEITHEESRYF 62

		           VV  +++P     +   +E+ F + +         + Y D    +++ +  +  E    F

		Sbjct: 21  VVFGRMIPAFENGVWTYTEERFSKPY--------FKQYED----DDMDVSYVEEEGKAAF 68

		

		Query: 63  FIIVDDVKAGFLKTNVGSAQTEQHLDNAFQIQRIYISQAFQGMGLGKRLFEFALQEARDL 122

		              +++   G +K          + +    I+ I +++ ++  G+G  L   A++ A++ 

		Sbjct: 69  LYYLENNCIGRIKIR-------SNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN 121

		

		Query: 123 GCDWAWLGVWERNFKAQIFYDKYGF 147

		                 L   + N  A  FY K+ F

		Sbjct: 122 HFCGLMLETQDINISACHFYAKHHF 146

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 53.9 bits (129), Expect = 3e-09

		 Identities = 51/349 (14%), Positives = 125/349 (35%), Gaps = 18/349 (5%)

		

		Query: 151 NAKPEDRRAIFEEAAGILKYKIRKKETESKLNQTQDNLDRLEDIIYELDGQVKPLEKQAA 210

		           N   + + +        LK    +   E  L+  ++ L + +  + E   +++ LE + A

		Sbjct: 66  NNTLKLKNSDLSFNNKALKDHNDELTEE--LSNAKEKLRKNDKSLSEKASKIQELEARKA 123

		

		Query: 211 TAKCYLELDGERRQTLLNLLVHDIEVGKSDLT----QTQEDLAEVKDKLTSYYEERHRLE 266

		             +  LE            +   +E  K+ L       ++ L    +  T+   +   LE

		Sbjct: 124 DLEKALEGAMNFSTADSAKI-KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE 182

		

		Query: 267 TENQELKQKRHQISEQISSDQQTLVDVTRLISDFERQIDLYTMESQQRSERKEETAARLS 326

		            E   L+ ++ ++ + +          +  I   E +           + RK +    L 

		Sbjct: 183 AEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKA-------ALAARKADLEKALE 235

		

		Query: 327 ELESLKAEAQASLDKVNQRQVKLNAELNTIAQELTAIQKDLEQFSDDPDTLIEHLREDYV 386

		              +      A +  +   +  L A    + + L          S      I+ L  +  

		Sbjct: 236 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAK----IKTLEAEKA 291

		

		Query: 387 SLMQEEAKVSNSLTQVTHDMESQTQALEAQAEEYKQAQADLLSAQEVASEAQKAYQAAQA 446

		           +L  E+A + +    +  + +S  + L+A  E  KQ +A+    +E    ++ + Q+ + 

		Sbjct: 292 ALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRR 351

		

		Query: 447 SLQNLLDSYKEKDQSYQVIDKDYQEAQTKMFDLMDHLKSKEARRQSLES 495

		            L    ++ K+ +  +Q +++  + ++     L   L +    ++ +E 

		Sbjct: 352 DLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEK 400

		

		

		

		 Score = 40.4 bits (94), Expect = 4e-05

		 Identities = 33/236 (13%), Positives = 73/236 (30%), Gaps = 12/236 (5%)

		

		Query: 774  AQIASKREAINDRIEAIKEDKDALGQQKQALLDRQSELQLKERDLQAELRFAKTESNRLQ 833

		                   E + +R +  + + + L  +   L      L+    +L  EL  AK +  +  

		Sbjct: 46   RSQTDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKND 105

		

		Query: 834  ADLSELTKESDSLKALLNNQVDEDQTDRLPQLQAQHKEAVQRKDDLEQELVRAKIQVQDY 893

		              LSE   +          Q  E +   L +                + L   + +    

		Sbjct: 106  KSLSEKASK---------IQELEARKADLEKALEGAMNFSTADSAKIKTL---EAEKAAL 153

		

		Query: 894  EGQLEDLEERLAKAGNRNEDLIRQQTRLEERESQISQSLRKFATQLAEDYQMTLEAAKGQ 953

		              +  DLE+ L  A N +     +   LE  ++ +     +    L      +   +   

		Sbjct: 154  AARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 213

		

		Query: 954  VTPLENVEQTRQNLQSLERSIKALGPVNVEAIAQFEEVKQRLDFLNGQKDDLLEAK 1009

		             T              LE++++     +    A+ + ++     L  ++ +L +A 

		Sbjct: 214  KTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL 269

		

		

		

		 Score = 40.0 bits (93), Expect = 6e-05

		 Identities = 44/243 (18%), Positives = 97/243 (39%), Gaps = 21/243 (8%)

		

		Query: 665 NKQNNSLFIKPELDALTTEISQIKAQLSDSEAKVEALKTKRKALQKALEDLKVDGENARL 724

		              N S     ++  L  E + + A+ +D E  +E       A    ++ L+   E A L

		Sbjct: 201 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLE--AEKAAL 258

		

		Query: 725 QEQRLGLEYQQALSDVEKNQVLVDSFKQGSQGSEGANLQTKSEQLKAELAQIASKREAIN 784

		           + ++  LE        +  +  ++     S   +   L+ +   L+AE A +  + + +N

		Sbjct: 259 EARQAELE--------KALEGAMNFSTADSAKIK--TLEAEKAALEAEKADLEHQSQVLN 308

		

		Query: 785 DRIEAIKEDKDALGQQKQALLDRQSELQLKERDLQAELRFAKTESNRLQADLSELTKESD 844

		              ++++ D DA  + K+ L   ++E Q  E   +     ++     L+ DL    +   

		Sbjct: 309 ANRQSLRRDLDASREAKKQL---EAEHQKLEEQNKI----SEASRQSLRRDLDASREAKK 361

		

		Query: 845 SLKALLNNQVDEDQTDRLPQ--LQAQHKEAVQRKDDLEQELVRAKIQVQDYEGQLEDLEE 902

		            L+A      ++++     +  L+     + + K  +E+ L  A  ++   E   ++LEE

		Sbjct: 362 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEE 421

		

		Query: 903 RLA 905

		              

		Sbjct: 422 SKK 424

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 73.7 bits (181), Expect = 1e-17

		 Identities = 35/154 (22%), Positives = 68/154 (44%), Gaps = 6/154 (3%)

		

		Query: 2   KLLVAEDQSMLRDALCQLLMLEDDVEEVHVASDGQEAIALLEKEEVDVAILDIEMPVKTG 61

		            +LVA+D + +R  L Q L       +V + S+       +   + D+ + D+ MP +  

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62

		

		Query: 62  LDVLEWIRANQRETKVVIVTTFKRKGYFKRALAAQVDAYVLKERSISDLMATIHTVLAGQ 121

		            D+L  I+  + +  V++++         +A       Y+ K   +++L+  I   LA  

		Sbjct: 63  FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122

		

		Query: 122 KEYSPELVEGVAFDNNPL---SQREQEVLAMVAQ 152

		           K   P  +E  + D  PL   S   QE+  ++A+

		Sbjct: 123 KR-RPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 38.3 bits (89), Expect = 3e-05

		 Identities = 64/344 (18%), Positives = 127/344 (36%), Gaps = 69/344 (20%)

		

		Query: 36  LVLTGLFTIAYLLIVYLKKAYSKW--IPFLWFYTLAYIIFMSISFQGGMMWFVFFNVNLL 93

		           + L GL           ++ + K      +     A ++        GM+WFV    N  

		Sbjct: 48  ISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVI-------GMVWFVA---NTS 97

		

		Query: 94  VWRFEDSIASYRFLSFLATLLILTSSSFLLTDDLSTHLMSLAITLFSLGMYYFQNRMRQE 153

		           +WR    I +      L   L +  +  ++T            +L   G ++F+N  + E

		Sbjct: 98  IWRLLAFINTKPVAFTLPLALSIIFNVVVVT---------FMWSLLYFGWHFFKNYKQAE 148

		

		Query: 154 RKMEEALAEKNRTINILSAENERNRIGRDLHDTLGHTFAMMSLKTELALKQMDKEQYDAA 213

		              +  +A   +   +++ + + N     + + L              ++ +  E    A

		Sbjct: 149 ID-QWKMASMAQEAQLMALKAQINP--HFMFNALN------------NIRALILEDPTKA 193

		

		Query: 214 RKNLEELNQISRDSMYEVREIINQLKYRTVAEEL------LELE--RLFDLSDIVLTVDS 265

		           R+ L  L+++ R S+          +  ++A+EL      L+L   +  D       ++ 

		Sbjct: 194 REMLTSLSELMRYSLRYSNA-----RQVSLADELTVVDSYLQLASIQFEDRLQFENQINP 248

		

		Query: 266 SLDLDSLSPVTQSTLSMVLRELANNVIKH---SQAERCQIRLN---RNHGIVLEFEDDGC 319

		           ++ +D   P       M+++ L  N IKH      +  +I L     N  + LE E+ G 

		Sbjct: 249 AI-MDVQVP------PMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS 301

		

		Query: 320 GF----KEVTGQELHSIRERLSLV---DGDLKILSQSHLTIIRV 356

		                 KE TG  L ++RERL ++   +  +K+  +       V

		Sbjct: 302 LALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345

		

		

		>ABC2TRNSPORT#ABC-2 type transport system membrane protein

		           signature.

		          Length = 262

		

		 Score = 28.0 bits (62), Expect = 0.030

		 Identities = 15/71 (21%), Positives = 29/71 (40%), Gaps = 1/71 (1%)

		

		Query: 138 LLLSSLVFLSFGLLLVQI-KSQQIMAIVGNIVFFGLAIIGGSWMPVTLFPKWVQHISEWT 196

		           + L+ L F S G+++  +  S         +V   +  + G+  PV   P   Q  + + 

		Sbjct: 154 IALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFL 213

		

		Query: 197 PIYHINQLVVN 207

		           P+ H   L+  

		Sbjct: 214 PLSHSIDLIRP 224

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 35.4 bits (81), Expect = 2e-04

		 Identities = 26/143 (18%), Positives = 49/143 (34%), Gaps = 29/143 (20%)

		

		Query: 33  CLALIGPNGAGKTTLMSCILGDKKASSGQVFIKGKKGKAQDQIAVLLQENTIPSQLKVKE 92

		            + L G  G GK+TL++ ++G    S     I   K   +      +         ++ E

		Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYE-----QIAGIVA---YELSE 649

		

		Query: 93  LIAFFQDISDNGLSKVEIQALLQF---KDDQYQQFADKLSGGQKRLLAFVLCLIGKPDIL 149

		           +             + + +A+  F   + D+Y+    +      R +    C   K   L

		Sbjct: 650 M---------TAFRRADAEAVKAFFSSRKDRYRGAYGRYVQDHPRQVVIW-CTTNKRQYL 699

		

		Query: 150 FLDEPTAGMDTTTRQRFWEIIND 172

		           F        D T  +RFW ++  

		Sbjct: 700 F--------DITGNRRFWPVLVP 714

		

		

		>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature.

		          Length = 428

		

		 Score = 28.0 bits (62), Expect = 0.033

		 Identities = 19/123 (15%), Positives = 43/123 (34%), Gaps = 21/123 (17%)

		

		Query: 106 RQIVTQAISSELKPTELDAIGTVD----NHLELLLVDSVDWEEEIEAVHLEILQEKINNY 161

		           +Q+V  A   +LKP  +   G +D    N      + +++ +  IE  ++E      + Y

		Sbjct: 51  KQVVKNAELLKLKPVLITDEGKIDDKSFNQSAFEALKAINKQTGIEINNVEPSSNFESAY 110

		

		Query: 162 IHFLES----------------KQYVERYGDSF-DKKVIHITFQYSPSDNGLAFLAAVQK 204

		              L +                KQY++ + +     ++  I   +        F +    

		Sbjct: 111 NSALSAGHKIWVLNGFKHQQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFN 170

		

		Query: 205 VLQ 207

		           + +

		Sbjct: 171 IKE 173

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 26.6 bits (58), Expect = 0.015

		 Identities = 11/46 (23%), Positives = 18/46 (39%)

		

		Query: 33  CVALIGPNGAGKTVLMSCILGDKKHSSGQVLIEGKWNSVNILDTFW 78

		            V L G  G GK+ L++ ++G    S     I    +S   +    

		Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV 643

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 41.6 bits (97), Expect = 2e-05

		 Identities = 50/391 (12%), Positives = 133/391 (34%), Gaps = 30/391 (7%)

		

		Query: 109 QKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFSRFLKE 168

		           Q+      I +     +   L    K + D  +++    +   ++          + L E

		Sbjct: 56  QERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEK-----LRKNDKSLSE 110

		

		Query: 169 DSKTKTQILKKIFGTGIFDRFQKSLEERLRQSNKDMDKRQAQIDSHFASQVWSEEELAVL 228

		            +    ++  +       ++  +         +  +   +A+  +  A +   E+ L   

		Sbjct: 111 KASKIQELEARKADL---EKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALE-- 165

		

		Query: 229 ASTPASEKLARLEEFLSQRQESLTEQKSILKAAHEDLAQLQKSFQTAQDLAKIFQELEQA 288

		            +   S   +   + L   + +L  +++ L+ A E       S   +  +  +  E    

		Sbjct: 166 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNF--STADSAKIKTLEAEKAAL 223

		

		Query: 289 KERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDLEIAQEALS 348

		             R     +        +     +++                 +  +LE+ LE A    +

		Sbjct: 224 AARKADLEKALEGAMNFSTADSAKIK------TLEAEKAALEARQAELEKALEGAMNFST 277

		

		Query: 349 EKQQAFEDVKAKKEELAIQSEDFLQKEEELETWKEDIIYSQSLAQEQEKIKRSTTNYKQL 408

		                 + ++A+K  L         ++ +LE   +  + + +    +  +  S    KQL

		Sbjct: 278 ADSAKIKTLEAEKAAL-------EAEKADLEHQSQ--VLNANRQSLRRDLDASREAKKQL 328

		

		Query: 409 EETYQQARKEVEMLNKSLSDLEANRLSLESLHEAEKLFQIVGYSVENQLAQDLKEIENLN 468

		           E  +Q+  ++ ++   S   L  +   L++  EA+K  +     +E Q        ++L 

		Sbjct: 329 EAEHQKLEEQNKISEASRQSLRRD---LDASREAKKQLEAEHQKLEEQNKISEASRQSLR 385

		

		Query: 469 QELTKTEKRHQTLSFDIDQAQEILKELEEEL 499

		           ++L  + +  + +   +++A   L  LE+  

		Sbjct: 386 RDLDASREAKKQVEKALEEANSKLAALEKLN 416

		

		

		

		 Score = 37.0 bits (85), Expect = 4e-04

		 Identities = 49/432 (11%), Positives = 114/432 (26%), Gaps = 50/432 (11%)

		

		Query: 393 QEQEKIKRSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLESLHEAEKLFQIVGYS 452

		             + K    + N K L++   +  +E+    + L   + +     S  +  +  +     

		Sbjct: 68  TLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEK 127

		

		Query: 453 VENQLAQDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLMIV 512

		                           + L   +        D+++A E                      

		Sbjct: 128 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK---------- 177

		

		Query: 513 QLQAELEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQAT 572

		                LE         A         +       N            E + A L+ R+A 

		Sbjct: 178 --IKTLEAEK------AALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 229

		

		Query: 573 LSEVASKRQDLLDQVTKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQY 632

		           L +      +     +    TLE     LE                              

		Sbjct: 230 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAE------------------------- 264

		

		Query: 633 YQELQKRYDKEETDYIRYQDELGKAQKKA-TDLAKTYQEAKAVLDQAQERLEDLQEAHPE 691

		            ++  +      T        L   +     + A    +++ +    Q    DL  +   

		Sbjct: 265 LEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREA 324

		

		Query: 692 LESVEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDV 751

		            + +E          ++  +     +      +      K ++ + + + +         

		Sbjct: 325 KKQLE---AEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASR 381

		

		Query: 752 KRLSAELEQSLKAEGALANDLEQVELWLIEV---NNQAIPMLQAKLTTYATLKQELQAQI 808

		           + L  +L+ S +A+  +   LE+    L  +   N +     +      A L+ +L+A+ 

		Sbjct: 382 QSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEA 441

		

		Query: 809 RKGQELLQNQEQ 820

		           +  +E L  Q +

		Sbjct: 442 KALKEKLAKQAE 453

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 65.6 bits (160), Expect = 9e-15

		 Identities = 27/118 (22%), Positives = 48/118 (40%), Gaps = 4/118 (3%)

		

		Query: 4   KINVILVDDHEMVRLGLKSFLNLQG-DVEVVGEAENGREGVDLALELRPDVVVMDLVMPE 62

		              +++ DD   +R  L   L+  G DV +   A      +        D+VV D+VMP+

		Sbjct: 3   GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG---DGDLVVTDVVMPD 59

		

		Query: 63  LDGVQATLELLKEWPEAKILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRK 120

		            +       + K  P+  +LV+++           E GA  Y+ K     E++  I +

		Sbjct: 60  ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 64.8 bits (158), Expect = 3e-14

		 Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 35/189 (18%)

		

		Query: 2   ILVTGANGQLGTELRHLLDERNEEYVAVD------------------------VAEMDIT 37

		            LVTGA G +G  +   L E   + V +D                          ++D+ 

		Sbjct: 3   YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62

		

		Query: 38  DADKVDEVFAEVKPTLVYHCAAYTAV-DAAEDEGKELDYAINVTGTENVAKAAEKHG-AT 95

		           D + + ++FA      V+      AV  + E+     D   N+TG  N+ +    +    

		Sbjct: 63  DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD--SNLTGFLNILEGCRHNKIQH 120

		

		Query: 96  LVYISTDYVFNGEKPVGQEWEVDDKPD-PQTEYGRTKRMGEELVEKHVTNYYI----IRT 150

		           L+Y S+  V+   + +   +  DD  D P + Y  TK+  E +   +   Y +    +R 

		Sbjct: 121 LLYASSSSVYGLNRKM--PFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178

		

		Query: 151 SWVFGNYGK 159

		             V+G +G+

		Sbjct: 179 FTVYGPWGR 187

		

		

		>PF04605#Virulence-associated protein D (VapD)

		          Length = 125

		

		 Score = 28.7 bits (64), Expect = 0.003

		 Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 5/44 (11%)

		

		Query: 7  RMILMFDMPTDTAEE-----RKAYRKFRKFLLSEGFIMHQFSVY 45

		          R  + FD+ T + E+     R+ Y   +KF+L  GF   Q+S Y

		Sbjct: 5  RKAINFDLSTKSLEKYFKDTREPYSLIKKFMLENGFEHRQYSGY 48

		

		

		>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein

		           signature.

		          Length = 166

		

		 Score =  152 bits (385), Expect = 6e-50

		 Identities = 62/155 (40%), Positives = 92/155 (59%), Gaps = 1/155 (0%)

		

		Query: 4   IAMFTGSFDPITNGHMDIIVRASKLFDELYIGLFYNKNKQDFWDVATRKRILDEVVADFP 63

		            A++ GSFDPIT GH+DII R  +LFD++Y+ +  N NKQ  + V  R   + + +A  P

		Sbjct: 2   NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLP 61

		

		Query: 64  NVKVITAHDSLAVDVARDLGVTYLVRGLRNATDFDYEANMDYFNKGLAPELETVYLIASH 123

		           N +V +    L V+ AR      ++RGLR  +DF+ E  M   NK LA +LETV+L  S 

		Sbjct: 62  NAQVDSFEG-LTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTST 120

		

		Query: 124 EVTPVSSSRVRELIYFGGDISSYVPQAVVKEVEAK 158

		           E + +SSS V+E+  FGG++  +VP  V   +  +

		Sbjct: 121 EYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQ 155

		

		

		>adhesinb#Adhesin B signature.

		          Length = 310

		

		 Score = 32.1 bits (73), Expect = 0.002

		 Identities = 22/76 (28%), Positives = 36/76 (47%), Gaps = 3/76 (3%)

		

		Query: 1  MKKWLAVMGILGLSVMTLAACGNKGDSKVSGEKQTITVATDSDTAPFTFKKGDDFKGYDI 60

		          MKK    + +L L+ + LAAC ++  S  +G  +   VAT+S  A  T     D    ++

		Sbjct: 1  MKKC-RFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDK--INL 57

		

		Query: 61 DLVKAVFKDSDKYEVK 76

		            +  V +D  +YE  

		Sbjct: 58 HSIVPVGQDPHEYEPL 73

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 38.8 bits (90), Expect = 2e-06

		 Identities = 17/56 (30%), Positives = 32/56 (57%), Gaps = 3/56 (5%)

		

		Query: 72  TLQRMAVLDDYQGQGLGSILLKEAEDFAQEQGFKSISLHAQ---LGALKFYLNNGY 124

		            ++ +AV  DY+ +G+G+ LL +A ++A+E  F  + L  Q   + A  FY  + +

		Sbjct: 91  LIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 30.0 bits (67), Expect = 0.007

		 Identities = 13/42 (30%), Positives = 20/42 (47%), Gaps = 1/42 (2%)

		

		Query: 33  ITLTGPSGGGKSTLLRIIASMISKTSGTLIFDGQPIESYDPI 74

		           + L G  G GKSTL+  +  +   +  T    G   +SY+ I

		Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSD-THFDIGTGKDSYEQI 639

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 29.2 bits (65), Expect = 0.004

		 Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 3/38 (7%)

		

		Query: 23  FFLGIPLSKILVLTVLSSIAEVLMHLVLGKKSKVTLSD 60

		           F  GIPL K+      S IA+ ++ LV G+   +T+ +

		Sbjct: 216 FKTGIPLKKL---AKPSDIADAVLFLVSGQAGHITMHN 250

		

		

		>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature.

		          Length = 136

		

		 Score = 25.2 bits (55), Expect = 0.029

		 Identities = 12/37 (32%), Positives = 19/37 (51%), Gaps = 7/37 (18%)

		

		Query: 32 GATVQGAIGGAIGGAFG-------GNVVLPVVGSVPG 61

		          G  V  A+G  IG AFG        ++++P +G + G

		Sbjct: 14 GNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIG 50

		

		

		>ALARACEMASE#Alanine racemase signature.

		          Length = 356

		

		 Score =  353 bits (907), Expect = e-123

		 Identities = 125/368 (33%), Positives = 188/368 (51%), Gaps = 19/368 (5%)

		

		Query: 5   LHRPTLAKVDLSAISENIEQVVSHIPKQVQTFAVVKANAYGHGAVEVAKHVSKQVDGFCV 64

		           + RP  A +DL A+ +N+  V        + ++VVKANAYGHG   +   +    DGF +

		Sbjct: 1   MTRPIQASLDLQALKQNLSIVRQAAT-HARVWSVVKANAYGHGIERIWSAI-GATDGFAL 58

		

		Query: 65  SNLDEALELRQAGIEQPILIL-GVVLPDGIPLAIQENISLTVASLEWLALAQKQELDLTG 123

		            NL+EA+ LR+ G + PIL+L G      + +  Q  ++  V S   L   Q   L    

		Sbjct: 59  LNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAP- 117

		

		Query: 124 LTCHIKVDSGMGRIGVRNLKDADNLIAGLKALGAD-VEGIFTHFATADEADDSKFKRQLS 182

		           L  ++KV+SGM R+G +       +   L+A+       + +HFA A+  D       ++

		Sbjct: 118 LDIYLKVNSGMNRLGFQP-DRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDG--ISGAMA 174

		

		Query: 183 FFTDLVDNLTDRPRLVHASNSATSIWHAATVFNTVRLGVVIYGLNPSGSVLEL-PYNIQP 241

		                 + L         SNSA ++WH    F+ VR G+++YG +PSG   ++    ++P

		Sbjct: 175 RIEQAAEGL---ECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRP 231

		

		Query: 242 ALSLETALIHVKTLPAGQDVGYGATYTTTDEEVIGTLPIGYADGWTRDL-QGFHVIVDGQ 300

		            ++L + +I V+TL AG+ VGYG  YT  DE+ IG +  GYADG+ R    G  V+VDG 

		Sbjct: 232 VMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGV 291

		

		Query: 301 LCPIVGRVSMDQITVRLPKV--YPLGTPVTLMGENGGASITATEVAEKRGTINYEVLCLL 358

		               VG VSMD + V L       +GTPV L G+     I   +VA   GT+ YE++C L

		Sbjct: 292 RTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGK----EIKIDDVAAAAGTVGYELMCAL 347

		

		Query: 359 SDRVPRSY 366

		           + RVP   

		Sbjct: 348 ALRVPVVT 355

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 1059 bits (2740), Expect = 0.0

		 Identities = 392/910 (43%), Positives = 551/910 (60%), Gaps = 72/910 (7%)

		

		Query: 1   MANILRKIIENDKG-EIKKLEKTAKKVESYADAMAALSDEELQAKTEEFKQRYQNGESLD 59

		           +  +L K+  +     ++++ K    + +    M  LSDEEL+ KT EF+ R + GE L+

		Sbjct: 2   LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEVLE 61

		

		Query: 60  QLLPEAFAVVREGAKRVLGLFPYRVQIMGGIVLHYGDVAEMRTGEGKTLTATMPVYLNAI 119

		            L+PEAFAVVRE +KRV G+  + VQ++GG+VL+   +AEMRTGEGKTLTAT+P YLNA+

		Sbjct: 62  NLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEMRTGEGKTLTATLPAYLNAL 121

		

		Query: 120 SGEGVHVITVNEYLSERDATEMGELYSWLGLSVGINLSSKSPAEKREAYNCDITYSTSSE 179

		           +G+GVHV+TVN+YL++RDA     L+ +LGL+VGINL       KREAY  DITY T++E

		Sbjct: 122 TGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPGMPAPAKREAYAADITYGTNNE 181

		

		Query: 180 VGFDYLRDNMVVRKENMVQRPLNFALVDEVDSVLIDEARTPLIVSGPVSSETNQLYHRAD 239

		            GFDYLRDNM    E  VQR L++ALVDEVDS+LIDEARTPLI+SGP    + ++Y R +

		Sbjct: 182 YGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDEARTPLIISGPAEDSS-EMYKRVN 240

		

		Query: 240 AFVKTLTED------------DYAIDIPTKTIGLNDSGIDKAEEFFN-------LENLYD 280

		             +  L                +++D  ++ + L + G+   EE           E+LY 

		Sbjct: 241 KIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTERGLVLIEELLVKEGIMDEGESLYS 300

		

		Query: 281 IDNVALTHYIDNALRANYIMLRDIDYVVSPEQEILIVDQFTGRTMEGRRFSDGLHQAIEA 340

		             N+ L H++  ALRA+ +  RD+DY+V  + E++IVD+ TGRTM+GRR+SDGLHQA+EA

		Sbjct: 301 PANIMLMHHVTAALRAHALFTRDVDYIVK-DGEVIIVDEHTGRTMQGRRWSDGLHQAVEA 359

		

		Query: 341 KEGVPVQEETKTSASITYQNMFRMYKKLSGMTGTGKTEEDEFREIYNMRVIPIPTNRPIQ 400

		           KEGV +Q E +T ASIT+QN FR+Y+KL+GMTGT  TE  EF  IY +  + +PTNRP+ 

		Sbjct: 360 KEGVQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMI 419

		

		Query: 401 RIDHDDLLYSTLDAKFRAVVQDVKRRYEKGQPVLIGTVAVETSDLISKMLVDAGIPHEVL 460

		           R D  DL+Y T   K +A+++D+K R  KGQPVL+GT+++E S+L+S  L  AGI H VL

		Sbjct: 420 RKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVL 479

		

		Query: 461 NAKNHEKEAHIIMNAGQRGAVTIATNMAGRGTDIKLG----------------------- 497

		           NAK H  EA I+  AG   AVTIATNMAGRGTDI LG                       

		Sbjct: 480 NAKFHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKA 539

		

		Query: 498 ------EGVLELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFG 551

		                 + VLE GGL +IGTERHESRRIDNQLRGRSGRQGD G S+FYLS+ED LMR F 

		Sbjct: 540 DWQVRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFA 599

		

		Query: 552 SDRIKHVLERLNADDEDIVIKSRMLTRQVESAQKRVEGNNYDTRKQVLQYDDVMREQREI 611

		           SDR+  ++ +L        I+   +T+ + +AQ++VE  N+D RKQ+L+YDDV  +QR  

		Sbjct: 600 SDRVSGMMRKLGMKP-GEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRA 658

		

		Query: 612 IYAERYDVITAERDLEPEIKAMIKRTINRMVDGHSRNDQEEALKGILNF--ARQALVPED 669

		           IY++R +++    D+   I ++ +      +D +      E +  I       +     D

		Sbjct: 659 IYSQRNELLDVS-DVSETINSIREDVFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLD 717

		

		Query: 670 AISLEDLKEVGEVTKRSVNYDAIKVYLTELADNVYDRQIKKLRSEEAIREFQKVLILMVV 729

		               E L +  E+ +     + ++  +   +  VY R+ + +   E +R F+K ++L  +

		Sbjct: 718 LPIAEWLDKEPELHE-----ETLRERILAQSIEVYQRKEEVVG-AEMMRHFEKGVMLQTL 771

		

		Query: 730 DNKWTDHIDALDQLRNAVGMRGYAQNNPIVEYQSESFKMFQDMIGAIEYDVTRTMMKAQI 789

		           D+ W +H+ A+D LR  + +RGYAQ +P  EY+ ESF MF  M+ +++Y+V  T+ K Q+

		Sbjct: 772 DSLWKEHLAAMDYLRQGIHLRGYAQKDPKQEYKRESFSMFAAMLESLKYEVISTLSKVQV 831

		

		Query: 790 H---EQSREHVNERVSTTATGNIQAHQADANGQ--------EIDFSKVGRNDFCPCGSGK 838

		               E        R+       +Q      +          +    KVGRND CPCGSGK

		Sbjct: 832 RMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGK 891

		

		Query: 839 KFKNCHGRKQ 848

		           K+K CHGR Q

		Sbjct: 892 KYKQCHGRLQ 901

		

		

		>cloacin#Cloacin signature.

		          Length = 551

		

		 Score = 31.6 bits (71), Expect = 0.001

		 Identities = 12/41 (29%), Positives = 19/41 (46%)

		

		Query: 111 GHSGGSYNVGGFDNSNSFGGGASTGGSFGESQPAQSTPNFG 151

		           GH+ G+++  G  N    G G   G S G    +++ P  G

		Sbjct: 8   GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGG 48

		

		

		>CHANLCOLICIN#Channel forming colicin signature.

		          Length = 522

		

		 Score = 30.4 bits (68), Expect = 0.032

		 Identities = 46/259 (17%), Positives = 85/259 (32%), Gaps = 30/259 (11%)

		

		Query: 484 AFEIARRLGLNEIIVKEAENLTDTDSDVNRIIEQLESQTVETQKRLEHIKDVEQENLKFN 543

		             E  R     E   KEAE       +  +  +++E +  ET+++L+  +  E+     +

		Sbjct: 126 EDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALS 185

		

		Query: 544 RAVKKLYNEFSHEYDKELEKAQKEIQEMVDTALAESDSILKNLHDKSQLKPHEVIDAKGK 603

		              K +         K+L  AQ E+ +M      E  ++   L      +  E+    GK

		Sbjct: 186 EEAKAV-----EIAQKKLSAAQSEVVKMD----GEIKTLNSRLSSSIHARDAEMKTLAGK 236

		

		Query: 604 LKKLAAQVDLSKNKVLRKAKKEKAARAPRVG----DDIIVTAYGQRGTLTSQAKNGNWEA 659

		             +LA      K       K    A  P       +         +     Q +    E 

		Sbjct: 237 RNELAQASAKYKELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASET 296

		

		Query: 660 QVGLIKMSLKADEFTLVRA------------QAEAQQPKKKQIN----VVKKAKKTSSDG 703

		           ++  I   +   +  + +             +AE    KK Q N     +K A   +   

		Sbjct: 297 RINRINADITQIQKAISQVSNNRNAGIARVHEAEENL-KKAQNNLLNSQIKDAVDATVSF 355

		

		Query: 704 PRARLDLRGKRYEEAMQEL 722

		            +   +  G++Y +  QEL

		Sbjct: 356 YQTLTEKYGEKYSKMAQEL 374

		

		

		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

		           signature.

		          Length = 290

		

		 Score = 30.9 bits (70), Expect = 0.003

		 Identities = 16/69 (23%), Positives = 26/69 (37%), Gaps = 13/69 (18%)

		

		Query: 16  QNIKISLVFETDTHIEIQAKLDYPAPSCPHCHGKMIKYDFQKPSKIPLLEQAGTPTLLRL 75

		              +     + +   E    L  P   CPHC+  +   +      IPLL      + L L

		Sbjct: 47  AEYRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALE-----NIPLL------SWLWL 95

		

		Query: 76  K-KCRFQCK 83

		           + +CR  C+

		Sbjct: 96  RGRCR-GCQ 103

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score =  622 bits (1606), Expect = 0.0

		 Identities = 181/671 (26%), Positives = 299/671 (44%), Gaps = 65/671 (9%)

		

		Query: 9   KTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGASQMDWMEQEQERGITITSAAT 68

		           K  NIG++AHVDAGKTT TE +LY +G I ++G   +G ++ D    E++RGITI +  T

		Sbjct: 2   KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61

		

		Query: 69  TAQWNGHRVNIIDTPGHVDFTIEVQRSLRVLDGAVTVLDSQSGVEPQTETVWRQATEYGV 128

		           + QW   +VNIIDTPGH+DF  EV RSL VLDGA+ ++ ++ GV+ QT  ++    + G+

		Sbjct: 62  SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121

		

		Query: 129 PRIVFANKMDKIGADFLYSVSTLHDRLQANAHPIQLPIGAEDDFRGIIDLIKMKAEIYTN 188

		           P I F NK+D+ G D       + ++L A                    +IK K E+Y N

		Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEI------------------VIKQKVELYPN 163

		

		Query: 189 DLGTDILEEDIPAEYVDQANEYREKLIEAVAETDEDLMMKYLEGEEITNDELKAAIRRAT 248

		              T+  E +                 + V E ++DL+ KY+ G+ +   EL+       

		Sbjct: 164 MCVTNFTESE---------------QWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRF 208

		

		Query: 249 INVEFFPVLCGSAFKNKGVQLMLDAVIDYLPSPLDIPAIKGINPDTGEEETRPASDEAPF 308

		            N   FPV  GSA  N G+  +++ + +   S                        ++  

		Sbjct: 209 HNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH-------------------RGQSEL 249

		

		Query: 309 AALAFKIMTDPFVGRLTFIRVYSGILQSGSYVMNTSKGKRERIGRILQMHANSRQEIEQV 368

		               FKI       RL +IR+YSG+L     V  + K K  +I  +         +I++ 

		Sbjct: 250 CGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKA 308

		

		Query: 369 YAGDIAAAIG----LKDTTTGDSLTDEKAKVILESIEVPEPVIQLMVEPKTKADQDKMAI 424

		           Y+G+I         L     GD+    +     E IE P P++Q  VEP     ++ +  

		Sbjct: 309 YSGEIVILQNEFLKLNS-VLGDTKLLPQR----ERIENPLPLLQTTVEPSKPQQREMLLD 363

		

		Query: 425 GLQKLAEEDPTFRVETNPETGETVISGMGELHLDVLVDRLKREHKVEANVGAPQVSYRET 484

		            L ++++ DP  R   +  T E ++S +G++ ++V    L+ ++ VE  +  P V Y E 

		Sbjct: 364 ALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTVIYME- 422

		

		Query: 485 FRAATQARGFFKRQSGGKGQFGDVWIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGL 544

		            R   +A      +      +  + +  +P   G G ++E+++  G + + F  AV +G+

		Sbjct: 423 -RPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSLGYLNQSFQNAVMEGI 481

		

		Query: 545 EESMANGVLAGYPMVDIKAKLYDGSYHDVDSSETAFKIAASLALKEAAKTAQPTILEPMM 604

		                 G L G+ + D K     G Y+   S+   F++ A + L++  K A   +LEP +

		Sbjct: 482 RYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYL 540

		

		Query: 605 LVTITVPEENLGDVMGHVTARRGRVDGMEAHGNTQIVRAYVPLAEMFGYATTLRSATQGR 664

		              I  P+E L             +   +   N  I+   +P   +  Y + L   T GR

		Sbjct: 541 SFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGR 600

		

		Query: 665 GTFMMVFDHYE 675

		              +     Y 

		Sbjct: 601 SVCLTELKGYH 611

		

		

		>60KDINNERMP#60kDa inner membrane protein signature.

		          Length = 548

		

		 Score =  161 bits (409), Expect = 3e-48

		 Identities = 67/207 (32%), Positives = 103/207 (49%), Gaps = 10/207 (4%)

		

		Query: 49  SFGGSIGLGIIIFTILIRAVMIPLYNRQIKSSRELQELQPELRRLQSEYPGRENREALAY 108

		           SF G+ G  III T ++R +M PL   Q  S  +++ LQP+++ ++       +++ ++ 

		Sbjct: 349 SFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGD--DKQRISQ 406

		

		Query: 109 AQQELYKEHGVNPYASFLPLIIQFPILMALYGALTRVPELREGSF-LWV-DLGQKDPYFI 166

		               LYK   VNP     PL+IQ PI +ALY  L    ELR+  F LW+ DL  +DPY+I

		Sbjct: 407 EMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAPFALWIHDLSAQDPYYI 466

		

		Query: 167 LPILAAAFTFLSTWLTNKVAKDRSAMLIVMNIMLPIFIFWFGTQISSGVALYWTVSNAFQ 226

		           LPIL     F    ++     D      +M  M P+    F     SG+ LY+ VSN   

		Sbjct: 467 LPILMGVTMFFIQKMSPTTVTD-PMQQKIMTFM-PVIFTVFFLWFPSGLVLYYIVSNLVT 524

		

		Query: 227 VVQILVFNNPFKIIAERNRLEAEEKER 253

		           ++Q  +         E+  L + EK++

		Sbjct: 525 IIQQQLIYR----GLEKRGLHSREKKK 547

		

		

		>ACETATEKNASE#Acetate kinase family signature.

		          Length = 400

		

		 Score =  498 bits (1285), Expect = e-179

		 Identities = 201/399 (50%), Positives = 267/399 (66%), Gaps = 6/399 (1%)

		

		Query: 3   KTIAINAGSSSLKWQLYEMPEEVVLAKGLIERIGLRDSVSTVKFADRSESQTLDIADHVQ 62

		           K + IN GSSSLK+QL E  +  VLAKGL ERIG+ DS+ T            D+ DH  

		Sbjct: 2   KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61

		

		Query: 63  AVKILLDDLI--RFDIIKSYDEITGVGHRVVAGGEYFKESSLVDEYALAKIEELSALAPL 120

		           A+K++LD L+   + +IK   EI  VGHRVV GGEYF  S L+ +  L  I +   LAPL

		Sbjct: 62  AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121

		

		Query: 121 HNPGAASGIRAFKELLPDITSVAVFDTAFHTSMPEVAYRYPVPNRYYTDYQVRKYGAHGT 180

		           HNP    GI+A  +++PD+  VAVFDTAFH +MP+ AY YP+P  YYT Y++RKYG HGT

		Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181

		

		Query: 181 SHQYVSQEAAKLLGKPIEETKIITAHVGNGVSITAVDGGKSVDTSMGLTPLGGVMMGTRT 240

		           SH+YVSQ AA++L KPIE  KIIT H+GNG SI AV  GKS+DTSMG TPL G+ MGTR+

		Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241

		

		Query: 241 GDLDPAIIPFIIDREPDMADAERIRHVFNKESGLLGISEKSSDMRDIIAGK-EAGDEKCT 299

		           G +DP+II +++++E     AE + ++ NK+SG+ GIS  SSD RD+     + GD++  

		Sbjct: 242 GSIDPSIISYLMEKEN--ISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQ 299

		

		Query: 300 LAYDLYVDRLRKYIAQYFGVMNGADAIVFTAGIGENSADVRASVLDGLTWFGIEVDPEKN 359

		           LA +++  R++K I  Y   M G D IVFTAGIGEN  ++R  +LDGL + G ++D EKN

		Sbjct: 300 LALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKN 359

		

		Query: 360 -VFGRVGDITTADSAVKVFVIPTDEELVIARDVERLKTK 397

		            V G    I+TADS V V V+PT+EE +IA+D E++   

		Sbjct: 360 KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVES 398

		

		

		>BCTERIALGSPG#Bacterial general secretion pathway protein G

		          signature.

		          Length = 145

		

		 Score = 51.0 bits (122), Expect = 2e-11

		 Identities = 28/99 (28%), Positives = 53/99 (53%), Gaps = 8/99 (8%)

		

		Query: 5  LKKLNAVKLRAFTLIEMLVVLLIISILLLLFVPNLSKQKDSVKETGNAAVVKVVDSQAEL 64

		          ++  +  K R FTL+E++VV++II +L  L VPNL   K+   +    + +  +++  ++

		Sbjct: 1  MRATD--KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDM 58

		

		Query: 65 YEMKNNKTAS----LAALVSEGQITQKQADSYN-DYYAK 98

		          Y++ N+   +    L +LV E       A +YN + Y K

		Sbjct: 59 YKLDNHHYPTTNQGLESLV-EAPTLPPLAANYNKEGYIK 96

		

		

		>BCTERIALGSPF#Bacterial general secretion pathway protein F

		           signature.

		          Length = 408

		

		 Score = 86.4 bits (214), Expect = 2e-21

		 Identities = 61/266 (22%), Positives = 122/266 (45%), Gaps = 11/266 (4%)

		

		Query: 32  DKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKNYLLPQLLE-- 89

		           +  G+L   L ++  Y  +  ++R ++ +   YP +L    I ++  L + ++P+++E  

		Sbjct: 143 ETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVAIAVVSILLSVVVPKVVEQF 202

		

		Query: 90  --GDGKNNWAVQLV---QIFPQLFFVSLCGLLVLGLILYLWVKRQSA--LVFYRRMAKIP 142

		                    + +++       + F   +   L+ G + +  + RQ    + F+RR+  +P

		Sbjct: 203 IHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRRLLHLP 262

		

		Query: 143 FIGQTVRLYTTAYYAREWGNLLGQGVDLLDLVALMQEQKSKLF-RELGADLEEALMLGQS 201

		            IG+  R   TA YAR    L    V LL  + +  +  S  + R   +   +A+  G S

		Sbjct: 263 LIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMSNDYARHRLSLATDAVREGVS 322

		

		Query: 202 FPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVWQNFFNRLNKATTFVQPLIFV 261

		             + +     F   +  +IA GE +  L   LE  A+   + F +++  A    +PL+ V

		Sbjct: 323 LHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQDREFSSQMTLALGLFEPLLVV 382

		

		Query: 262 IVAVVIVMIYVAMLLPMYQNMEGMMS 287

		            +A V++ I +A+L P+ Q +  +MS

		Sbjct: 383 SMAAVVLFIVLAILQPILQ-LNTLMS 407

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 27.5 bits (61), Expect = 0.024

		 Identities = 12/78 (15%), Positives = 26/78 (33%), Gaps = 4/78 (5%)

		

		Query: 7   AKLQNRSGVLNRFTGVLSRRQVNIESISVGATENPDVSRITIIIDVN----SHNEVEQII 62

		             L             L  +   I +  +G T      ++   I       +  E  ++ 

		Sbjct: 191 DLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVT 250

		

		Query: 63  KQLNRQIDVIRIRDITDV 80

		            ++N    V+R++D+  V

		Sbjct: 251 LRVNSDGSVVRLKDVARV 268

		

		

		>FLAGELLIN#Flagellin signature.

		          Length = 507

		

		 Score = 36.6 bits (84), Expect = 3e-04

		 Identities = 34/310 (10%), Positives = 84/310 (27%), Gaps = 2/310 (0%)

		

		Query: 215 ATGVDTLSSGASAYTSGVSTLSGALSQLNSNSEAVNSAAGQFASGAEAMNTLVTGANSLS 274

		              V +L               G L     N    ++ A         +N+     ++ +

		Sbjct: 161 KIDVKSLGLDGFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTA 220

		

		Query: 275 TALSQMATATSLSEEQQTQLSSLSANLTDLNTAIQNLNTAVSNTSFPSGTSTTSVDTSSI 334

		             +       + + +  T  +  +  +    T      TA +     +       DT   

		Sbjct: 221 PTVPDKVYVNAANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDY 280

		

		Query: 335 ATYLSNISSTASSIATASATDKANDLAAVQGTAAYQSLTADQQAEIASAISNAGSTASSY 394

		                 I +   +      +   N        A   +  A+  A    +  N  ++  + 

		Sbjct: 281 KGVTFTIDTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNG 340

		

		Query: 395 ASTIASDVSSMSTALSSLAGTTTTSSGESSNLVSLQTSISGIASSANTLLPVASSTISSM 454

		             T      + S  LS L             +       +  A+     L   +  I   

		Sbjct: 341 QFTFDDKTKNESAKLSDLEANNAVKGESKITVNG--AEYTANAAGDKVTLAGKTMFIDKT 398

		

		Query: 455 QANIANVNSVLVNQLSPGAIQVASGVSRAQSTLATGASNLLTGLSTYTGAVSTIASGAQT 514

		            + ++ + +              + +  A S +    S+L    + +  A++ + +    

		Sbjct: 399 ASGVSTLINEDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTN 458

		

		Query: 515 LDANSSTLMN 524

		           L++  S + +

		Sbjct: 459 LNSARSRIED 468

		

		

		

		 Score = 35.0 bits (80), Expect = 0.001

		 Identities = 30/295 (10%), Positives = 86/295 (29%), Gaps = 3/295 (1%)

		

		Query: 259 GAEAMNTLVTGANSLSTALSQMATATSLSEEQQTQLSSLSANLTDLNTAIQNLNTAVSNT 318

		           G             L ++   +    + +         +++     +T    +   V   

		Sbjct: 171 GFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVN 230

		

		Query: 319 SFPSGTSTTSVDTSSIATYLSNISSTASSIATASATDKANDLAAVQGTAAYQSLTADQQA 378

		           +     +T   + +   T +    +T S+  TA A   A  +   +    +         

		Sbjct: 231 AANGQLTTDDAENN---TAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTI 287

		

		Query: 379 EIASAISNAGSTASSYASTIASDVSSMSTALSSLAGTTTTSSGESSNLVSLQTSISGIAS 438

		           +  +     G  +++      +   +  TA ++     T  S ++     +    +    

		Sbjct: 288 DTKTGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDK 347

		

		Query: 439 SANTLLPVASSTISSMQANIANVNSVLVNQLSPGAIQVASGVSRAQSTLATGASNLLTGL 498

		           + N    ++    ++     + +        +  A    +   +      T +       

		Sbjct: 348 TKNESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLIN 407

		

		Query: 499 STYTGAVSTIASGAQTLDANSSTLMNGFSTLKSGTNVLNTGVQQLAIGGNNLTNG 553

		                A  + A+   ++D+  S +    S+L +  N  ++ +  L     NL + 

		Sbjct: 408 EDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSA 462

		

		

		

		 Score = 31.9 bits (72), Expect = 0.009

		 Identities = 29/299 (9%), Positives = 75/299 (25%), Gaps = 3/299 (1%)

		

		Query: 158 TSTYVGAVFKSMSQLQGGMGTAANGASQLYAGAGALQSGGQILSNGLGTLAGSTQTLATG 217

		                G    ++  L+          +                     T       +   

		Sbjct: 171 GFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVN 230

		

		Query: 218 VDTLSSGASAYTSGVSTLSGALSQLNSNSEAVNSAAGQFASGAEAMNTLVTGANSLSTAL 277

		                       +  +      ++  + +    + AG    G E       G        

		Sbjct: 231 AANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTK 290

		

		Query: 278 SQMATATSLSEE-QQTQLSSLSANLTDLNTAIQNLNTAVSNTSFPSGTSTTSVDTSSIAT 336

		           +       +S      +++   A++T     +       S   + S  +           

		Sbjct: 291 TGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKN 350

		

		Query: 337 YLSNISSTASSIATASATDKANDLAAVQGTAAYQSLTADQQAEIASAISNAGSTASSYAS 396

		             + +S   ++ A    +    + A     AA   +T   +         A   ++    

		Sbjct: 351 ESAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDK--TASGVSTLINE 408

		

		Query: 397 TIASDVSSMSTALSSLAGTTTTSSGESSNLVSLQTSISGIASSANTLLPVASSTISSMQ 455

		             A+   S +  L+S+    +      S+L ++Q       ++    +   +S  S ++

		Sbjct: 409 DAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIE 467

		

		

		>HTHTETR#TetR bacterial regulatory protein HTH signature.

		          Length = 215

		

		 Score = 45.8 bits (108), Expect = 2e-08

		 Identities = 17/84 (20%), Positives = 37/84 (44%)

		

		Query: 5  QRRSLTKKALLDALVICLKDQDFNEITTIRLVQTAGISRSSFYTHYKDKFEMIDSYQKEL 64

		          Q    T++ +LD  +     Q  +  +   + + AG++R + Y H+KDK ++     +  

		Sbjct: 7  QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66

		

		Query: 65 FHKLEYIFDKYEGKKEGAFLEIFE 88

		             +  +  +Y+ K  G  L +  

		Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLR 90

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 26.8 bits (59), Expect = 0.048

		 Identities = 5/26 (19%), Positives = 11/26 (42%)

		

		Query: 91  PKAGKLEVKVNATTDNGNLHLTIVDN 116

		                 ++ +  T DNG + L + + 

		Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENT 299

		

		

		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

		           signature.

		          Length = 290

		

		 Score = 30.9 bits (70), Expect = 0.009

		 Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 14/70 (20%)

		

		Query: 16  QNIKISLVFETDTHIEIQAKLDYPAPSCPHCHGKMIKYDFQKPSKIPLLEQAGTPTLLRL 75

		              +     + +   E    L  P   CPHC+  +   +      IPLL      + L L

		Sbjct: 47  AEYRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALE-----NIPLL------SWLWL 95

		

		Query: 76  KKRRFQCKSC 85

		           + R   C+ C

		Sbjct: 96  RGR---CRGC 102

		

		

		>FLGFLGJ#Flagellar protein FlgJ signature.

		          Length = 313

		

		 Score = 52.8 bits (126), Expect = 1e-10

		 Identities = 40/147 (27%), Positives = 71/147 (48%), Gaps = 10/147 (6%)

		

		Query: 45  KGFIENLAPTAQKMSKNYGVPASILLSQAAYESNYGSSLLSVK----YHNIYSLPARPGQ 100

		           K F+  L+  AQ  S+  GVP  ++L+QAA ES +G   +  +     +N++ + A    

		Sbjct: 150 KAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNW 209

		

		Query: 101 E--HIYLKDNVYSKGKWQYQKVDFAVFRDWSSSMSSYLEELRQGRWGESTYKEVAGTTSY 158

		           +     +    Y  G+ +  K  F V+  +  ++S Y+  L +       Y  V    S 

		Sbjct: 210 KGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTR----NPRYAAVTTAASA 265

		

		Query: 159 KVAAEKLQAAGFNSDPDYAKHLISIIE 185

		           +  A+ LQ AG+ +DP YA+ L ++I+

		Sbjct: 266 EQGAQALQDAGYATDPHYARKLTNMIQ 292

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 37.0 bits (85), Expect = 3e-05

		 Identities = 22/81 (27%), Positives = 34/81 (41%), Gaps = 11/81 (13%)

		

		Query: 6    KKEEVKEEKATETT---EEVVEEAKEATETTEEVVEETKETSELEEAQARAEEFENKYLR 62

		            K  E  E+ ATETT    EV +EAK   +   +  E  +  SE +E Q    +       

		Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK------- 1101

		

		Query: 63   VHAEMQNIQRRAKEERQQLQK 83

		                    + +AK E ++ Q+

		Sbjct: 1102 -ETATVEKEEKAKVETEKTQE 1121

		

		

		

		 Score = 33.5 bits (76), Expect = 4e-04

		 Identities = 17/79 (21%), Positives = 34/79 (43%), Gaps = 7/79 (8%)

		

		Query: 16   TETTEEVVEEAKEATETTE----EVVEETKETSELEEAQARAEEFE---NKYLRVHAEMQ 68

		            +ETTE V E +K+ ++T E    +  E T +  E+ +      +     N+  +  +E +

		Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETK 1093

		

		Query: 69   NIQRRAKEERQQLQKYRSQ 87

		              Q    +E   ++K    

		Sbjct: 1094 ETQTTETKETATVEKEEKA 1112

		

		

		

		 Score = 32.0 bits (72), Expect = 0.001

		 Identities = 29/169 (17%), Positives = 63/169 (37%), Gaps = 23/169 (13%)

		

		Query: 7    KEEVKEEKATETTE-EVVEEAKEATETTEEVVEETKETSELEEAQARAEEFENKYLRVHA 65

		              E KE + TET E   VE+ ++A   TE+  E  K TS++   Q ++E           

		Sbjct: 1089 GSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSET---------- 1138

		

		Query: 66   EMQNIQRRAKEERQQ-----LQKYRSQDLAKAILPALDNIERALAVEGLTDD-VKKGLEM 119

		                +Q +A+  R+      +++ +SQ    A          +   + +T+         

		Sbjct: 1139 ----VQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194

		

		Query: 120  IQESLINALKEEGIEEIAADGEF--NHNFHMAIQTMPADDEHPADTIAQ 166

		            + E+  N         + ++      +    +++++P + E    +   

		Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSND 1243

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score =  156 bits (395), Expect = 1e-44

		 Identities = 77/364 (21%), Positives = 145/364 (39%), Gaps = 60/364 (16%)

		

		Query: 2   SKIIGIDLGTTNSAVAVLEG----TEPKIIANPEGNRTTPSVVSFKNGEIIVGDAAKRQA 57

		           S  + IDLGT N+ + V        EP ++A  +    +P  V        VG  AK+  

		Sbjct: 10  SNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRAGSPKSV------AAVGHDAKQML 63

		

		Query: 58  VTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKSYAEEYLGEKVTKAVITVP 117

		              P  + +I+       K       +  +++    ++ + S +         + ++ VP

		Sbjct: 64  GRTPGNIAAIRPM-----KDGVIADFFVTEKMLQHFIKQVHSNS---FMRPSPRVLVCVP 115

		

		Query: 118 AYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDKEEKILVFDLGGGTFDVS 177

		                 +R+A +++ + AG     ++ EP AAA+  GL    +    +V D+GGGT +V+

		Sbjct: 116 VGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGL-PVSEATGSMVVDIGGGTTEVA 174

		

		Query: 178 ILELGDGVFDVLATAGDNKLGGDDFDQKIIDYMVEEFKKENGIDLSTDKMALQRLKDAAE 237

		           ++ L   V      +   ++GGD FD+ II+Y+   +    G             +  AE

		Sbjct: 175 VISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSLIG-------------EATAE 216

		

		Query: 238 KAKKDLS----GVTSTQISLPFITAGEAGPLHLEMTLTRAKFDDLTRDLVERTKTPVRQA 293

		           + K ++     G    +I +      E  P    +          + +++E  + P+   

		Sbjct: 217 RIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN---------SNEILEALQEPLTGI 267

		

		Query: 294 LSDAGLSL--------SDIDE--VILVGGSTRIPAVVEAVKAETGKEPNKSVNPDEVVAM 343

		           +S   ++L        SDI E  ++L GG   +  +   +  ETG     + +P   VA 

		Sbjct: 268 VSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVAR 327

		

		Query: 344 GAAI 347

		           G   

		Sbjct: 328 GGGK 331

		

		

		>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature.

		          Length = 591

		

		 Score = 28.2 bits (62), Expect = 0.014

		 Identities = 12/40 (30%), Positives = 19/40 (47%), Gaps = 1/40 (2%)

		

		Query: 48  YLGKKE-GAIVGGLSAFLIDLLSSAPQWMFISLFIHGAQG 86

		           YL K + G        +L    + A QW+F  +F +G +G

		Sbjct: 232 YLSKVQYGNATPAADLYLWTSATPAVQWLFTLVFDYGERG 271

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		          signature.

		          Length = 347

		

		 Score = 26.3 bits (58), Expect = 0.023

		 Identities = 16/43 (37%), Positives = 23/43 (53%), Gaps = 4/43 (9%)

		

		Query: 24 KDKGIKLNHPEAVALITDYVLEGAREGKTVAQLMDEARNLLTR 66

		          K +GI LN P  VA+  D     A   K+VA +  +A+ +L R

		Sbjct: 27 KGQGIVLNEPSVVAIRQD----RAGSPKSVAAVGHDAKQMLGR 65

		

		

		>UREASE#Urea amidohydrolase (urease) protein signature.

		          Length = 570

		

		 Score =  993 bits (2568), Expect = 0.0

		 Identities = 318/573 (55%), Positives = 413/573 (72%), Gaps = 4/573 (0%)

		

		Query: 1   MSFKMDREEYAQHYGPTVGDSVRLGDTNLFATIEKDFTVYGQESKFGGGKVLRDGMGVSA 60

		           MS++M R  YA  +GPTVGD VRL DT LF  +EKDFT +G+E KFGGGKV+RDGMG S 

		Sbjct: 1   MSYRMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQ 60

		

		Query: 61  TETRDNPSVVDTIITGATIIDYTGIIKADIGIRDGKIVAIGRGGNPDTMDNVDFVVGAST 120

		             TR+    VDT+IT A I+D+ GI+KADIG++DG+I AIG+ GNPD    V  +VG  T

		Sbjct: 61  V-TREG-GAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGT 118

		

		Query: 121 EAIAAEGLIVTAGGIDLHVHYISADLPEFGMDNGITTLFGGGTGPADGSNATTCTPGKFH 180

		           E IA EG IVTAGG+D H+H+I     E  + +G+T + GGGTGPA G+ ATTCTPG +H

		Sbjct: 119 EVIAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWH 178

		

		Query: 181 ITRMLQAVDDMPANFGFLAKGVGSETEVVEEQIKAGAAGIKTHEDWGATYAGIDNSLKVA 240

		           I RM++A D  P N  F  KG  S    + E +  GA  +K HEDWG T A ID  L VA

		Sbjct: 179 IARMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVA 238

		

		Query: 241 DKYDVSFAVHTDSLNEGGFMENTLESFQGRTVHTFHTEGSGGGHAPDIMVFAGKENILPS 300

		           D+YDV   +HTD+LNE GF+E+T+ + +GRT+H +HTEG+GGGHAPDI+   G+ N++PS

		Sbjct: 239 DEYDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPS 298

		

		Query: 301 STNPTNPYTTNAIGELLDMVMVCHHLDPKIPEDVSFAESRVRKQTVAAEDVLHDMGALSI 360

		           STNPT PYT N + E LDM+MVCHHL P IPED++FAESR+RK+T+AAED+LHD+GA SI

		Sbjct: 299 STNPTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSI 358

		

		Query: 361 MTSDAMAMGRVGEVVMRCWQLADKMKAQRGPLEGDSEFNDNNRIKRYVAKYTINPAITNG 420

		           ++SD+ AMGRVGEV +R WQ ADKMK QRG L+ ++  NDN R+KRY+AKYTINPAI +G

		Sbjct: 359 ISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHG 418

		

		Query: 421 IADYIGSVEVGKFADLVIWEPAQFGAKPKLVLKGGMLTYGVMGDAGSSLPTPQPRIMRKL 480

		           ++  IGS+EVGK ADLV+W PA FG KP +VL GG +    MGD  +S+PTPQP   R +

		Sbjct: 419 LSHEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPM 478

		

		Query: 481 YGAYGQAVHKTNITFVSQYAYDHGIKEEIGLNKIVLPVKNTR-NLTKRDMKLNDYAPKTI 539

		           +GAYG++   +++TFVSQ + D G+   +G+ K ++ V+NTR  + K  M  N   P  I

		Sbjct: 479 FGAYGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPH-I 537

		

		Query: 540 RIDPQTFDVFIDDELVTCEPIHTTSLSQRYFLF 572

		            +DP+T++V  D EL+TCEP     ++QRYFLF

		Sbjct: 538 EVDPETYEVRADGELLTCEPATVLPMAQRYFLF 570

		

		

		>TCRTETA#Tetracycline resistance protein signature.

		          Length = 399

		

		 Score = 37.1 bits (86), Expect = 1e-04

		 Identities = 31/151 (20%), Positives = 61/151 (40%), Gaps = 10/151 (6%)

		

		Query: 41  SLMLVGIYQTLENIISVIFNLF-GGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWL 99

		               +GI      I+  +      G ++     +R ++L  I  G   + L+F   + W+

		Sbjct: 244 DATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA-TRGWM 302

		

		Query: 100 IYAVVITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSL 159

		            + +++   +LA       PA +A     V+ +   +L   L +  ++  +V PL+  ++

		Sbjct: 303 AFPIMV---LLASGGIGM-PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAI 358

		

		Query: 160 YGLLGLYGILRLDGITFIASGLLILFIRPIL 190

		           Y       I   +G  +IA   L L   P L

		Sbjct: 359 YA----ASITTWNGWAWIAGAALYLLCLPAL 385

		

		

		>ADHESNFAMILY#Adhesin family signature.

		          Length = 309

		

		 Score = 34.1 bits (78), Expect = 5e-04

		 Identities = 16/62 (25%), Positives = 25/62 (40%), Gaps = 7/62 (11%)

		

		Query: 4  KKILGITVLAVASTVALAACGAGGNKSAKDDKTLTVGIMTLDNTTEPVWDKVKELAKDKG 63

		          KK+  + VL ++  + L AC +G   +    K   V       T   + D  K +A DK 

		Sbjct: 2  KKLGTLLVLFLS-AIILVACASGKKDTTSGQKLKVV------ATNSIIADITKNIAGDKI 54

		

		Query: 64 VT 65

		            

		Sbjct: 55 DL 56

		

		

		>GPOSANCHOR#Gram-positive coccus surface protein anchor signature.

		          Length = 539

		

		 Score = 27.0 bits (59), Expect = 0.010

		 Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 5/45 (11%)

		

		Query: 11 QRFSIRKYSFGVASVLLGTSLV---FASQALADEHHEVATTSDTI 52

		          + +S+RK   G ASV +  +++          +E   VAT S T 

		Sbjct: 8  RHYSLRKLKTGTASVAVALTVLGAGLVVN--TNEVSAVATRSQTD 50

		

		

		>CARBMTKINASE#Bacterial carbamate kinase signature.

		          Length = 314

		

		 Score = 41.7 bits (98), Expect = 1e-06

		 Identities = 19/83 (22%), Positives = 40/83 (48%), Gaps = 6/83 (7%)

		

		Query: 158 INADYLARAVAISLGSKKLILMTDVKGVLEN-----GQVLNHLNIVDVQKKIDSG-VITG 211

		           I+ D     +A  + +   +++TDV G          Q L  + + +++K  + G    G

		Sbjct: 213 IDKDLAGEKLAEEVNADIFMILTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAG 272

		

		Query: 212 GMIPKIQSAVQTVKSGVDQVIIG 234

		            M PK+ +A++ ++ G ++ II 

		Sbjct: 273 SMGPKVLAAIRFIEWGGERAIIA 295

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 32.5 bits (74), Expect = 0.008

		 Identities = 10/73 (13%), Positives = 25/73 (34%), Gaps = 6/73 (8%)

		

		Query: 806 YLPLADLLNVEEELARLEKELAKWQKELDMVGKKLSNERFVANAKPEVVQKERDKQKDYQ 865

		            +    +L  E +      EL  ++ +L+ +  ++       +AK E     +  + +  

		Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI------LSAKEEYQLVTQLFKNEIL 301

		

		Query: 866 AKYDAIVVRIDEM 878

		            K       I  +

		Sbjct: 302 DKLRQTTDNIGLL 314

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score = 78.7 bits (194), Expect = 6e-18

		 Identities = 52/153 (33%), Positives = 81/153 (52%), Gaps = 10/153 (6%)

		

		Query: 13  VNIGTIGHVDHGKTTLTAAI---TTVLARRLPSAVNTPKDYASIDAAPEERERGITINTA 69

		           +NIG + HVD GKTTLT ++   +  +      +V+  K     D    ER+RGITI T 

		Sbjct: 4   INIGVLAHVDAGKTTLTESLLYNSGAITE--LGSVD--KGTTRTDNTLLERQRGITIQTG 59

		

		Query: 70  HVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGAILVVASTDGPMPQTREHILLSRQV 129

		              ++ E      ID PGH D++  +    + +DGAIL++++ DG   QTR      R++

		Sbjct: 60  ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119

		

		Query: 130 GVKHLIVFMNKVDLVDDEELLELVEMEIRDLLS 162

		           G+   I F+NK+D    +  L  V  +I++ LS

		Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLS 149

		

		

		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

		           signature.

		          Length = 290

		

		 Score = 30.9 bits (70), Expect = 0.009

		 Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 14/70 (20%)

		

		Query: 16  QNIKISLVFETDTHIEIQAKLDYPAPSCPHCHGKMIKYDFQKPSKIPLLEQAGTPTLLRL 75

		              +     + +   E    L  P   CPHC+  +   +      IPLL      + L L

		Sbjct: 47  AEYRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALE-----NIPLL------SWLWL 95

		

		Query: 76  KKRRFQCKSC 85

		           + R   C+ C

		Sbjct: 96  RGR---CRGC 102

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 31.3 bits (71), Expect = 5e-04

		 Identities = 8/57 (14%), Positives = 21/57 (36%), Gaps = 5/57 (8%)

		

		Query: 56  QQRQQTEASNYQ--TLQDYNDAVANAAS---DLEKAQDVLNQTIIVSDVNGTVVEVA 107

		           ++  Q     ++   L        N      +L K ++    ++I + V+  V ++ 

		Sbjct: 286 KEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLK 342

		

		

		>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature.

		          Length = 1104

		

		 Score = 26.6 bits (58), Expect = 0.033

		 Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%)

		

		Query: 20  GKQSTTTWADDNGNPLKPTEPGSKEPGTVSGYEYVKTVTDPNGNIKHIFKNVEMPTPRPV 79

		           G+     W   +G      +  + +      YE   TVTD NG I    K +++   +PV

		Sbjct: 803 GEIKAYEWDFGDGEKSNEAKA-THKYNKTGEYEVKLTVTDNNGGINTESKKIKVVEDKPV 861

		

		Query: 80  EPSQPATPKD 89

		           E    + P +

		Sbjct: 862 EVINESEPNN 871

		

		

		>PF05272#Virulence-associated E family protein

		          Length = 892

		

		 Score = 38.1 bits (88), Expect = 1e-04

		 Identities = 18/94 (19%), Positives = 30/94 (31%), Gaps = 22/94 (23%)

		

		Query: 384 MVAIVGPTGAGKSTIINLLMRFYDVTAGSISVDGHDIRNLSRKDYRKQFGMVLQDAWLFE 443

		            V + G  G GKST+IN L+     +     +              K     +     +E

		Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTG-----------KDSYEQIAGIVAYE 646

		

		Query: 444 GTIKENLRFGNLEA---TDEEIVEAAKAANVDHF 474

		                      + A    D E V+A  ++  D +

		Sbjct: 647 --------LSEMTAFRRADAEAVKAFFSSRKDRY 672

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 46.4 bits (110), Expect = 1e-07

		 Identities = 51/335 (15%), Positives = 119/335 (35%), Gaps = 54/335 (16%)

		

		Query: 118 NLEAISLYLGIS-FFLSTGITLILRKLLLSHQRLRIATSKGNWLYQFIVPLLSIFFAFTI 176

		           + +  S+   I+   +   +T   R  +     L++   +        V    +      

		Sbjct: 36  SPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIIL----RVLPACVVIGMVW 91

		

		Query: 177 SAIQG--------------GVFGADYLSIISLSSLIVLTLSSLYFNLYLARQQQQYYQNQ 222

		                                     LSII    ++    S LYF        + Y Q +

		Sbjct: 92  FVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGW---HFFKNYKQAE 148

		

		Query: 223 LEKEQLQFQVREIQQSQEEYQRLQSLR-----HDLKNKHLTLLSLLEKNPEEAKDYLYSL 277

		           +++ ++    +E Q        L +L+     H + N    + +L+ ++P +A++ L SL

		Sbjct: 149 IDQWKMASMAQEAQ--------LMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSL 200

		

		Query: 278 TDSIVGEQTFYSKNQTINFLLNQKLHHLKDEIEME---------IDCFVPQELSIQPDIL 328

		           ++ ++     YS  + ++  L  +L  +   +++           +  +   +     + 

		Sbjct: 201 SE-LMRYSLRYSNARQVS--LADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQ-VP 256

		

		Query: 329 AVILGNCLDNSIAACLRLPNKERNLSLNIRYFQQNLFINIRNNFDEKEKSTRKSRQKDGW 388

		            +++   ++N I   +    +   + L        + + + N      K+T++S    G 

		Sbjct: 257 PMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES---TGT 313

		

		Query: 389 GLRNIDALVQEYQGN---IKHFIKDGQYQIEILLP 420

		           GL+N+   +Q   G    IK   K G+    +L+P

		Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 64.9 bits (158), Expect = 3e-14

		 Identities = 28/138 (20%), Positives = 58/138 (42%), Gaps = 12/138 (8%)

		

		Query: 39  KLLNQRTPDIHCVFLDINMPGINGIDVAQKIRKFNPFIPIIFVTSYRDYMEQV--FEVQT 96

		           + +     D   V  D+ MP  N  D+  +I+K  P +P++ +++   +M  +   E   

		Sbjct: 41  RWIAAGDGD--LVVTDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGA 98

		

		Query: 97  FDYIVKPIEPQKLMKVLDRILRFLDIGQA-LFTFSFGKHNYSVPSS-------DIVFFEK 148

		           +DY+ KP +  +L+ ++ R L       + L   S         S+        +    +

		Sbjct: 99  YDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQ 158

		

		Query: 149 DKRSVFIYTKTGTYKSLL 166

		              ++ I  ++GT K L+

		Sbjct: 159 TDLTLMITGESGTGKELV 176

		

		

		>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature.

		          Length = 398

		

		 Score = 27.7 bits (61), Expect = 0.005

		 Identities = 11/40 (27%), Positives = 19/40 (47%), Gaps = 2/40 (5%)

		

		Query: 23  DHPYYQDYEEEFYDEDYEANYQP--SAYKSRRIENAKRNQ 60

		           D   Y  Y++ F+D D + N+    S Y +  I +   +Q

		Sbjct: 86  DKNAYDLYQDHFWDPDTDNNFSKDNSWYLAYSIPDTGESQ 125

		

		

		>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family

		           signature.

		          Length = 290

		

		 Score = 30.9 bits (70), Expect = 0.009

		 Identities = 16/70 (22%), Positives = 25/70 (35%), Gaps = 14/70 (20%)

		

		Query: 16  QNIKISLVFETDTHIEIQAKLDYPAPSCPHCHGKMIKYDFQKPSKIPLLEQAGTPTLLRL 75

		              +     + +   E    L  P   CPHC+  +   +      IPLL      + L L

		Sbjct: 47  AEYRSYFNPDDEGVDEPPYNLMVPRSCCPHCNHPITALE-----NIPLL------SWLWL 95

		

		Query: 76  KKRRFQCKSC 85

		           + R   C+ C

		Sbjct: 96  RGR---CRGC 102