>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.041 Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 94 GDGLGVTLAGGYRFGNPDGWHA--GVGLATERFPGARFMAPHGI 135 G+G +L G RF + DGW LA R G + A +G+ Sbjct: 761 THGVGASLEAGRRFTHADGWFLEPQAELAVFRAGGGAYRAANGL 804
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.9 bits (129), Expect = 6e-11 Identities = 21/66 (31%), Positives = 30/66 (45%) Query: 25 PAQHRATETYEHILAVTAQLLGDVGVERLSTNLVCAHAGLTPPALYRYFPNKYALLSELG 84 + A ET +HIL V +L GV S + AG+T A+Y +F +K L SE+ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 85 TRLMQR 90 Sbjct: 64 ELSESN 69
>cloacin#Cloacin signature. Length = 551 Score = 28.5 bits (63), Expect = 0.046 Identities = 18/57 (31%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 92 TLGISIATDALTLALVDFSGAVLACSEVGLTDTTLYGVL-TQLQAADAALLARVDTA 147 L +SI+ AL+ A+ D A+ + GL LYGVL +Q+ D +++++ T+ Sbjct: 102 GLAVSISAGALSAAIADIMAALKGPFKFGLWGVALYGVLPSQIAKDDPNMMSKIVTS 158
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 25.9 bits (57), Expect = 0.018 Identities = 16/83 (19%), Positives = 33/83 (39%), Gaps = 2/83 (2%) Query: 3 IIIWLIVGG-IVGWLASIIMRRDAQQGIILNVVVGIVGALIAGFL-FGGGINQAITLWTF 60 ++I + G +V WL +I R G+ + + + I + A F Sbjct: 163 MVICMTAGTCVVMWLGELITDRGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEF 222 Query: 61 VWSLVGAVILLAIVNLVTRGRLR 83 + +I++A+V V + + R Sbjct: 223 GTVIAVGLIMVALVVFVEQAQRR 245
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 29.6 bits (66), Expect = 0.009 Identities = 26/83 (31%), Positives = 38/83 (45%), Gaps = 3/83 (3%) Query: 55 QPALPDRDTG-WSHSGEYLLVGLGEGVRLGVDLERIRARPRVLEIAQRFFHPDEIALLAA 113 QP PD G SH L + R+G+D+E+I ++ E+A DE +L A Sbjct: 77 QPLWPDGLFGSISHCATTALAVISRQ-RIGIDIEKIMSQHTATELAPSIIDSDERQILQA 135 Query: 114 LAPDAQHALFFRLWCAKEALLKA 136 AL + AKE++ KA Sbjct: 136 SLLPFPLALTL-AFSAKESVYKA 157
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 28.8 bits (64), Expect = 0.039 Identities = 22/100 (22%), Positives = 35/100 (35%), Gaps = 17/100 (17%) Query: 363 MPIGLQVPDGEDANGR-PRWEAIANGDPGVPRGREQEIATLLRFISRARIRNTVWLTADV 421 MP ++ + N +W +A D RG Q A R+RN ++ Sbjct: 19 MPESVKPVSDFELNNYLGKWYEVARLDHSFERGLSQVTAEY-------RVRNDGGISV-- 69 Query: 422 HYCAAHYYHPDRAAFQQFEPFWEFVGGP----LNAGSFGP 457 Y ++ +++ E FV G L FGP Sbjct: 70 ---LNRGYSEEKGEWKEAEGKAYFVNGSTDGYLKVSFFGP 106
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.004 Identities = 22/125 (17%), Positives = 38/125 (30%), Gaps = 8/125 (6%) Query: 171 AVGAGSIADQHEVQGLLTPAEGAQAQTTARFPGPVRSLRVNVGDRVRA-GQVLATVESNL 229 V + +++ + A+ T F + D + LA E Sbjct: 269 RVYKSQLE---QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQ 325 Query: 230 SLTTYSVSAPISGVVLARNA-SLGSNAGEGQALFEIA-DLSTLWVDLHIFGADAGHITAG 287 + + AP+S V + G + L I + TL V + D G I G Sbjct: 326 QASV--IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 288 APVAV 292 + Sbjct: 384 QNAII 388
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 754 bits (1949), Expect = 0.0 Identities = 244/1073 (22%), Positives = 415/1073 (38%), Gaps = 72/1073 (6%) Query: 7 RFAIAQRWLMLALTGVLIAIGAWSFSRLPIDATPDITNVQVQVNTAAPGYSPLESEQRIT 66 F I + L +L+ GA + +LP+ P I V V+ PG + +T Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 67 FPLETVLAGLPGLESTRSLS-RYGLSQVTAVFADGTDLYFARQQVAERLQQVKSQLPADL 125 +E + G+ L S S G +T F GTD A+ QV +LQ LP ++ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 126 EPQLGPIATGLGEIFMYTVEAKPNARKPDGSAWTATDLRTLQDWVVRPQLRNVPGVTEVN 185 + Q + M D T D+ V+ L + GV +V Sbjct: 123 QQQGISVEKSSSSYLMVA------GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 186 TIGGYARQIHITPDPARLVALGFTLDDVARAVESNNRNIGAGYI------ERNGQQFLVR 239 G + I D L T DV ++ N I AG + + Sbjct: 177 LFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 240 VPGQVDDIAQIGAVVLD-RRAGVPIRVRDVAQVGEGRELRTGAATQDGSEVVLGTVFMLV 298 + + + G V L G +R++DVA+V G E A +G + + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLAT 295 Query: 299 GANSRTVAQAAAQRLEVANASLPAGVQAVPVYDRTALVDRTIVTVAKNLIEGALLVIVVL 358 GAN+ A+A +L P G++ + YD T V +I V K L E +LV +V+ Sbjct: 296 GANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVM 355 Query: 359 FLLLGNVRAALITAAVIPLAMLFTLTGMVRGGVSGNLMSLG--ALDFGLIVDGAVIIVEN 416 +L L N+RA LI +P+ +L T + G S N +++ L GL+VD A+++VEN Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 417 CLRRFGDAQRRLGRVLERDERFELTAEATAEVIRPSLFGLGIITAVYLPVFALTGIEGKM 476 R + ++ E T ++ +++ + +++AV++P+ G G + Sbjct: 416 VERVMME---------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAI 466 Query: 477 FHPMAITVVLALTGAMLLSLTFVPAAIALLLGGKVAEHE----------NRAMRWARGVY 526 + +IT+V A+ ++L++L PA A LL AEH N + Y Sbjct: 467 YRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHY 526 Query: 527 APLLDRALRHGRWVAIAALATVALCAVLATRLGSEFIPNLDEGDVALHALRIPGTSLE-- 584 + + L + VA VL RL S F+P D+G G + E Sbjct: 527 TNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERT 586 Query: 585 QAITMQSTLEKRIKQFPEVAHVFGKLGTAEVATDPMPPSVADTFLIMHPRAQWPDPRKRK 644 Q + Q T + V VF G + + F+ + P + Sbjct: 587 QKVLDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDENSA 643 Query: 645 AQLLAEIEEAVKQLPGNNYEFTQPIQM-RMNELISGVRADVA-IKVYGDDLDTLVRLGQR 702 ++ + + ++ F P M + EL + D I G D L + + Sbjct: 644 EAVIHRAKMELGKIRDG---FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 703 VQEIASAVPGA-ADVSLEQATGLPMLAVVPDRAALAGYGLNPGVVQDTVAAAVGGQEAGQ 761 + +A+ P + V + D+ G++ + T++ A+GG Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 762 LFEGDRRFDIVVRLPESLRQDPTALADLPIPLRGDGERADADESSRAAGWRSGEPITVPL 821 + R + V+ R P + L + +GE VP Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSA-NGE-------------------MVPF 800 Query: 822 REVAKIDTVLGPNQINREDGKRRIVITANVRDRDLGSFVAEVRQRVQTQV-KLPTGYWIG 880 V G ++ R +G + I G+ + ++ KLP G Sbjct: 801 SAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP---GTSSGDAMALMENLASKLPAGIGYD 857 Query: 881 YGGTFEQLISASQRLAWVVPGTLVLIFALLYWSFGSLRDALVVFSGVPLALTGGVLALAL 940 + G Q + + +V + V++F L + S + V VPL + G +LA L Sbjct: 858 WTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATL 917 Query: 941 RGLALSISAGVGFIALSGVAVLNGLVMIAFVRSL-RADGMPLERALREGALARLRPVLMT 999 + VG + G++ N ++++ F + L +G + A RLRP+LMT Sbjct: 918 FNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMT 977 Query: 1000 ALVAALGFVPMAFNVGAGAEVQRPLATVVIGGIVSSTLLTLLVLPVLYRWLHR 1052 +L LG +P+A + GAG+ Q + V+GG+VS+TLL + +PV + + R Sbjct: 978 SLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 77.2 bits (190), Expect = 3e-16 Identities = 81/431 (18%), Positives = 156/431 (36%), Gaps = 32/431 (7%) Query: 639 DPRKRKAQLLAEIEEAVKQLPGNNYEFTQPIQMRMNELISGVRADVAIKVYGD-DLDTLV 697 DP + Q+ +++ A LP E Q S + + D + Sbjct: 99 DPDIAQVQVQNKLQLATPLLPQ---EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDIS 155 Query: 698 RLGQR-VQEIASAVPGAADVSLEQATGLPMLAVVPDRAALAGYGLNPGVVQDTVAAAVGG 756 V++ S + G DV L + + D L Y L P V + + Sbjct: 156 DYVASNVKDTLSRLNGVGDVQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQ 213 Query: 757 QEAGQLFEGDRRFDIVVRLPESLRQDPTALADLPIPLRGDGERADADESSRAAGWRSGEP 816 AGQL P Q A + + +E + + + Sbjct: 214 IAAGQL----------GGTPALPGQQLNAS------IIAQTRFKNPEEFGKVTLRVNSDG 257 Query: 817 ITVPLREVAKI-DTVLGPNQINREDGKRRIVITANVR-DRDLGSFVAEVRQRVQT-QVKL 873 V L++VA++ N I R +GK + + + ++ ++ Q Sbjct: 258 SVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFF 317 Query: 874 PTGYWIGYGGTFEQLISASQRLAWVVP---GTLVLIFALLYWSFGSLRDALVVFSGVPLA 930 P G + Y ++ + VV ++L+F ++Y ++R L+ VP+ Sbjct: 318 PQGMKVLY--PYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVV 375 Query: 931 LTGGVLALALRGLALSISAGVGFIALSGVAVLNGLVMIAFV-RSLRADGMPLERALREGA 989 L G LA G +++ G + G+ V + +V++ V R + D +P + A + Sbjct: 376 LLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSM 435 Query: 990 LARLRPVLMTALVAALGFVPMAFNVGAGAEVQRPLATVVIGGIVSSTLLTLLVLPVLYRW 1049 ++ A+V + F+PMAF G+ + R + ++ + S L+ L++ P L Sbjct: 436 SQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCAT 495 Query: 1050 LHRQRAPRRER 1060 L + + Sbjct: 496 LLKPVSAEHHE 506
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 31.0 bits (70), Expect = 0.020 Identities = 18/54 (33%), Positives = 25/54 (46%), Gaps = 3/54 (5%) Query: 1 MRRCLFLS-VALALHAGAAGAQTPPVAVTAIPA--QPLARALNTLSRQTGLQFV 51 MRR L ++ V L L A AQ P + +P Q + + TL T L F+ Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFI 54
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 38.2 bits (88), Expect = 2e-04 Identities = 33/148 (22%), Positives = 61/148 (41%), Gaps = 29/148 (19%) Query: 149 HPAIAQIHDVGTDAHG---QPYLVMEYLRGEPITWWCDEHRLSL-----HARV------- 193 HP +A +H + +G + L+M+ + G W C + +L ++ Sbjct: 190 HPNLANVHGMAVVPYGNRKEEALLMDEVDG----WRCSDTLRTLADSWKQGKINSEAYWG 245 Query: 194 ---LLMLRVGEAVQHAHQKGVIHRDLKPSNVLVSEIDGRPMPGVIDFGIAVDATNPGMTY 250 + R+ + H + GV+H D+KP NV+ G P+ VID G+ + + Sbjct: 246 TIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPV--VIDLGLHSRSGEQPKGF 303 Query: 251 AHDRGTPGYMSPEQARGAQDVDARSDIY 278 T + +PE G +SD++ Sbjct: 304 -----TESFKAPELGVGNLGASEKSDVF 326
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 67.6 bits (165), Expect = 1e-14 Identities = 44/179 (24%), Positives = 69/179 (38%), Gaps = 39/179 (21%) Query: 253 SLSAPISAQAAQWGIAPATPPDAAPVPPPPVRLKQLLSAQERAGLLRVDEQADGQTRVRL 312 LS +S + Q AP P AP P P V+ K L Sbjct: 182 MLSLGVSYRFGQGEAAPVVAP--APAPAPEVQTK----------------------HFTL 217 Query: 313 SSAAMFASGGVEVELQQRGLIAQIAAAIEQL---PGRVIVVGHTDDVPVRSLRFQDNYAL 369 S +F ++ + + + Q+ + + L G V+V+G+TD + + N L Sbjct: 218 KSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAY----NQGL 273 Query: 370 SAARAQALAQVLQAQLSTPGRVEAIGAGASQPIA--------QPVQLPANRARNRRVEI 420 S RAQ++ L ++ ++ A G G S P+ Q L A +RRVEI Sbjct: 274 SERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.007 Identities = 26/204 (12%), Positives = 55/204 (26%), Gaps = 11/204 (5%) Query: 626 RIDPGSSLLRHSALEVRLDAAIAEAVAAGQLTTARTEVEQARAAFPDSLRLQLRSAEVGV 685 ++ + + L A E L+ + + PD Q S E + Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 686 AEQQVRRTPVAATPRDADSARTALAADLANPSTDPAWRARIDAELAALP---------AA 736 + + + L A T A R + Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 737 ERSSQGSALAEAISTAVAVQSDPAQLAGAQALVDFGLGLAPRSASLLAQRMRLQTLEHQF 796 +++ A+ E + V ++ ++ + A L+ Q + + L+ + Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD-KL 304 Query: 797 EQALARESA-EAELAARIESLRRA 819 Q ELA E + + Sbjct: 305 RQTTDNIGLLTLELAKNEERQQAS 328
>PF04647#Accessory gene regulator B Length = 212 Score = 29.0 bits (65), Expect = 0.007 Identities = 7/42 (16%), Positives = 15/42 (35%) Query: 64 SDARTRPLSGYRVTRKLRSQVVAVFVIVMLISIILLTLHKCT 105 D +S + L+ + V +++ SI L+ Sbjct: 124 VDNPRNLISNTEQRKTLKLKTSMVLMVLFGGSIGAYRLYTHQ 165
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (260), Expect = 9e-28 Identities = 64/334 (19%), Positives = 114/334 (34%), Gaps = 42/334 (12%) Query: 2 MRVLVTGAAGMIGRRVASALLQRGDAVAGLDDLSSG--MSLPHGLHAA--------IVAD 51 M+ LVTGAAG IG V+ LL+ G V G+D+L+ +SL D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 VGERETVAVALREFRADALIHLAAIHHIPTCETQRMRCLQVNVVGTESVLHAASDAALRQ 111 + +RE + + + + N+ G ++L ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 112 VVIASSGAVYAWGDGA---LDEHVSATDARDNYALSKLCNEAQLRLWCAAAN--GRRGRA 166 ++ ASS +VY G S YA +K NE + ++ G Sbjct: 121 LLYASSSSVY--GLNRKMPFSTDDSVDHPVSLYAATKKANE---LMAHTYSHLYGLPATG 175 Query: 167 ARLFNTIA-HDDPNAHLIPDVLAQLAADPAATPTLRLGNLQPCRDYLHADDAAAGLIALL 225 R F P+ L A L + RD+ + DD A +I L Sbjct: 176 LRFFTVYGPWGRPDMALFKFTKAMLEGKSIDV----YNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 226 D---------------DARPDPAFDVFNLCSGVEHSVAELVEQIGAVLGRSPRLEVDPQR 270 D A + V+N+ + + + ++ + LG + + P + Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ 291 Query: 271 QRRIDRLHQLGDPGKAARVLGWRARWSLREALQR 304 D L D V+G+ ++++ ++ Sbjct: 292 PG--DVLETSADTKALYEVIGFTPETTVKDGVKN 323
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 1e-04 Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 3/90 (3%) Query: 51 YILGQEQVLFLVVTEGDHVIGRLYLGGDAATTVCLLDILLLACRRGQGIGTALIEALVA- 109 Y+ + + FL E ++ IGR+ + + + DI + R +G+GTAL+ + Sbjct: 59 YVEEEGKAAFLYYLE-NNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEW 117 Query: 110 QVTRDGRNVVLQVDKHN-PALELYRRLGFR 138 ++L+ N A Y + F Sbjct: 118 AKENHFCGLMLETQDINISACHFYAKHHFI 147
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.0 bits (111), Expect = 2e-07 Identities = 22/135 (16%), Positives = 55/135 (40%), Gaps = 4/135 (2%) Query: 439 AVHDAFAADNHDLERQQDRMQAAQDALQEAREQLASLGPELAQAKQEAQQQAREAQQQIR 498 A +A LE ++ + A + L++A E + + + + + + + Sbjct: 204 NFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA 263 Query: 499 DVAQQHRQAQYAYAAAVRQADALSRHQVEL-AKQAALQGRAEARRGQREAAQAQVEA--- 554 ++ + A A + L + L A++A L+ +++ R++ + ++A Sbjct: 264 ELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASRE 323 Query: 555 EKAQAEADQAQAEAE 569 K Q EA+ + E + Sbjct: 324 AKKQLEAEHQKLEEQ 338 Score = 44.7 bits (105), Expect = 7e-07 Identities = 32/153 (20%), Positives = 59/153 (38%), Gaps = 13/153 (8%) Query: 431 DASRDAQAAVHDAFAADNHDLERQQDRMQAAQDALQEAREQLASLGPELAQAKQEAQQQA 490 + + + A +A LE ++ ++A Q L++A E + AK + + Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFS-TADSAKIKTLEAE 289 Query: 491 REAQQQIRDVAQQHRQAQYAYAAAVRQADALSR---------HQ-VELAKQAALQGRAEA 540 + A + + + Q A ++R+ SR HQ +E + + R Sbjct: 290 KAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSL 349 Query: 541 RR--GQREAAQAQVEAEKAQAEADQAQAEAERA 571 RR A+ Q+EAE + E +EA R Sbjct: 350 RRDLDASREAKKQLEAEHQKLEEQNKISEASRQ 382 Score = 29.6 bits (66), Expect = 0.033 Identities = 39/146 (26%), Positives = 66/146 (45%), Gaps = 20/146 (13%) Query: 431 DASRDAQAAV---HDAFAADNHDLERQQDRMQAAQDALQEAREQLASLGPELAQAKQEAQ 487 DASR+A+ + H N E + ++ DA +EA++QL + E + +++ + Sbjct: 319 DASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEA---EHQKLEEQNK 375 Query: 488 QQAREAQQQIRDVA---QQHRQAQYAYAAAVRQADALSRHQVEL--AKQAALQGRAEARR 542 Q RD+ + +Q + A A + AL + EL +K+ + +AE Sbjct: 376 ISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAE--- 432 Query: 543 GQREAAQAQVEAE-KAQAEADQAQAE 567 QA++EAE KA E QAE Sbjct: 433 -----LQAKLEAEAKALKEKLAKQAE 453
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 30.9 bits (70), Expect = 0.017 Identities = 6/33 (18%), Positives = 10/33 (30%) Query: 418 YYTGGFDQFLSNLYKHYQINPLHSQDAPRRAAL 450 G +S L + P+ + A L Sbjct: 138 LTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFL 170
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 71.6 bits (175), Expect = 1e-16 Identities = 45/188 (23%), Positives = 81/188 (43%), Gaps = 8/188 (4%) Query: 3 KRILVTGASSGFGRLAAQALAAAGHTVYASMRDTAGRNAGVAQEMADLACKQQLALHALE 62 K +TGA+ G G A+ LA+ G + A + V+ A+ + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-----P 63 Query: 63 LDVQSQASADAAVACIVAQAGGLDVVVHNAGHMVFGPAEAFTAEQLAHVYDINVLGTQRV 122 DV+ A+ D A I + G +D++V+ AG + G + + E+ + +N G Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 123 NRAALPQLRAQQQGLLVWVSSSSSAGGTPPY-LGPYFAAKAAMDALAVQYARELTRWGIE 181 +R+ + ++ G +V V S+ G P + Y ++KAA EL + I Sbjct: 124 SRSVSKYMMDRRSGSIVTV--GSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 TSIIVPGA 189 +I+ PG+ Sbjct: 182 CNIVSPGS 189
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 107 bits (268), Expect = 3e-30 Identities = 81/249 (32%), Positives = 125/249 (50%), Gaps = 12/249 (4%) Query: 6 KVALVTGASRGIGAAIAQRLAGDGFAVVLNYAGHADEADRLVRSIEADGGRAISVQADVS 65 K+A +TGA++GIG A+A+ LA G A + + ++ +++V S++A+ A + ADV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQG-AHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 66 DPAAVARLFAAAETAFGGVDVLVNNAGIMQLATLADSDDALFDKHIAINLKGNFNTLRQA 125 D AA+ + A E G +D+LVN AG+++ + D ++ ++N G FN R Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 126 AR--RLRNGGRIVNLSTSVVGLKLETYGVYAATKAAVETLTAILSKELRGRAITVNAVAP 183 ++ R G IV + ++ G+ + YA++KAA T L EL I N V+P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 184 GPTGTA----LFLDGKSPELI-----ERLSKANPLERLGCPDDIAAAVAFLVGPDGGWIN 234 G T T L+ D E + E PL++L P DIA AV FLV G I Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 235 GQVLRANGG 243 L +GG Sbjct: 248 MHNLCVDGG 256
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 283 bits (724), Expect = 2e-93 Identities = 118/288 (40%), Positives = 165/288 (57%), Gaps = 23/288 (7%) Query: 76 YDAQQGTTLPGTLARD--EGAPATQDVAVTEAYDYLGATHDFFQTVYGRDSIDAAGMPLI 133 YD + T LPG+L D A+ D A +A+ Y G +D+++ V+GR S D + + Sbjct: 270 YDGRNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIR 329 Query: 134 GTVHYERGYDNAFWNGEQMVFGDGDGEVFNRFTIAIDVVGHELTHGVTERTANLIYQGQS 193 TVHY RGY+NAFWNG QMV+GDGDG+ F F+ IDVVGHELTH VT+ TA L+YQ +S Sbjct: 330 STVHYGRGYNNAFWNGSQMVYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNES 389 Query: 194 GALNESISDVFGVLIKQYTLGQSADQADWIIGAGLLMPGIQGVGLRSMQAPGSAYDDPAL 253 GA+NE++SD+FG L++ Y + DW IG + PG+ G LRSM P Sbjct: 390 GAINEAMSDIFGTLVEFY----ANRNPDWEIGEDIYTPGVAGDALRSMSDP--------- 436 Query: 254 GKDPQPATMAGYVDTQEDDGGVHYNSGIPNHAFYRAA-------VAIGGAAWEKTGRIWY 306 K P + +D+GGVH NSGI N A Y + V++ G +K G+I+Y Sbjct: 437 AKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGGVHYGVSVTGIGRDKMGKIFY 496 Query: 307 RALTGGELAASADFATFADLTASVASADYGANSSEAVALRQAWRDVGV 354 RAL L +++F+ A+ YG+ S E +++QA+ VGV Sbjct: 497 RALV-YYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.3 bits (97), Expect = 5e-06 Identities = 41/211 (19%), Positives = 71/211 (33%), Gaps = 35/211 (16%) Query: 71 PTAQLIATFATFTVAF-LVRPIGGMVFGPLGDRYGRQKFLAATMILMALGTFSIGLIPAY 129 + + A + + L++ V G L DR+GR+ L ++ A+ + P Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF- 95 Query: 130 QRIGLWAPALLLLARVLQGFSTGGEYGGAATFIAEYATDRNR----GLMGSWLEFGTLGG 185 LW +L + R++ G TG A +IA+ R G M + FG + G Sbjct: 96 ----LW---VLYIGRIVAGI-TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG 147 Query: 186 YIAGAATVTALHMSVTPAQMLDWGWRVPFLIAGPLGLLGLYMRMKLEETPAFRAHTEQSE 245 + G M + PF A L L + + E Sbjct: 148 PVLGGL-------------MGGFSPHAPFFAAAALNGLNFLTGC------FLLPESHKGE 188 Query: 246 QRERQTAAQGLTTLLRLHWPQLLKCVGLVLV 276 +R + A R W + + V ++ Sbjct: 189 RRPLRREALNPLASFR--WARGMTVVAALMA 217 Score = 32.1 bits (73), Expect = 0.004 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 9/103 (8%) Query: 267 LLKCVGLVLVFNVTDYMLLTYMPSYLSVTMGYAESKGLLLIILVMLVMMPLNIVGGMFSD 326 L VG+ L+ V +L + S + +L+ L L+ V G SD Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHS------NDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 327 KLGRRPMIIGACIALFALAIPCLLLVGSGNDGLIFAGLMLLGL 369 + GRRP++ ++L A+ ++ + +++ G ++ G+ Sbjct: 69 RFGRRPVL---LVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI 108
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 29.5 bits (66), Expect = 0.043 Identities = 21/59 (35%), Positives = 27/59 (45%), Gaps = 2/59 (3%) Query: 348 SGGGTSRPVPAPQRLSPPAAPAAPADPAGSP--GDAPTLAPLQRRDLQPQATDALIAAR 404 SGGGT P+ P +L+PP +P A D P + QR+ QP D AA Sbjct: 120 SGGGTDAPIRKPFKLTPPQPTMSPISIADRDFGIDIPNIPQAQRQAAQPPLNDQKRAAA 178
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 36.3 bits (84), Expect = 1e-04 Identities = 31/146 (21%), Positives = 56/146 (38%), Gaps = 12/146 (8%) Query: 25 QAVVGQDAVVEQLL--IGLLAGG--HCLLEGAPGLGKTLLVRSLGQA---LDLQFRRVQ- 76 +VG+ A ++++ + L ++ G G GK L+ R+L + F + Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 77 --FTPDLMPSDILGTELLEEDHGTGHRHFRFQQGPIFTNLLLADELNRTPPKTQAALLEA 134 DL+ S++ G E RF+Q T L DE+ P Q LL Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT--LFLDEIGDMPMDAQTRLLRV 254 Query: 135 MSERTVSYAGTTYALPAPFFVLATQN 160 + + + G + + ++A N Sbjct: 255 LQQGEYTTVGGRTPIRSDVRIVAATN 280
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 26.1 bits (57), Expect = 0.016 Identities = 14/27 (51%), Positives = 15/27 (55%) Query: 34 LFRSRAGSVSVGAHAALWHLGQVVFGA 60 L+ A S SVGA AALW G GA Sbjct: 185 LYTDTAFSWSVGARAALWECGCATLGA 211
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 37.2 bits (86), Expect = 8e-05 Identities = 20/102 (19%), Positives = 32/102 (31%), Gaps = 3/102 (2%) Query: 96 DPNQFNAYVMQAHLAVARGDLDEAERLSRTAARLAPEHPQLLAVDGVVEMRRGQDDRALS 155 Q + + + G ++A ++ + L + G GQ D A+ Sbjct: 35 TLEQLYSLAFNQYQS---GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIH 91 Query: 156 LLTRAAEQLPDDARVLFSLGFAYLQKEHFAFAERAFERVIEL 197 + A + R F LQK A AE EL Sbjct: 92 SYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQEL 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 495 bits (1276), Expect = e-175 Identities = 205/471 (43%), Positives = 282/471 (59%), Gaps = 14/471 (2%) Query: 8 SHIWVVDDDRSVRFVLSTALRDAGYAVDGFDSAAAALQALGMRPTPDLLFTDVRMPGEDG 67 + I V DDD ++R VL+ AL AGY V +AA + + DL+ TDV MP E+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVVMPDENA 62 Query: 68 LTLLDKLKSKHPQLPVIVMSAYTDVASTAGAFRGGAHEFLSKPFDLDDAVALAARALPDA 127 LL ++K P LPV+VMSA + A GA+++L KPFDL + + + RAL + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 128 DAGVEEIVATRLAEGSASLIGDTPAMQALFRAIGRLAQAPLSVLINGETGTGKELVARAL 187 ++ ++ L+G + AMQ ++R + RL Q L+++I GE+GTGKELVARAL Sbjct: 123 KRRPSKLEDD--SQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 188 HNESPRARKPFVALNTAAIPAELLESELFGHETGAFTGATKRHIGRFEQADGGTLFLDEI 247 H+ R PFVA+N AAIP +L+ESELFGHE GAFTGA R GRFEQA+GGTLFLDEI Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 248 GDMPLPLQTRLLRVLAENEFFRVGGRELIRVDVRVIAATHQDLEALVEQGRFRADLLHRL 307 GDMP+ QTRLLRVL + E+ VGGR IR DVR++AAT++DL+ + QG FR DL +RL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 308 DVVRLQLPPLRERRGDIAQLAENFLAMAGRKLDMLPKRLSSAALEDLRQYDWPGNVRELE 367 +VV L+LPPLR+R DI L +F+ A K + KR ALE ++ + WPGNVRELE Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQA-EKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 368 NVCWRLAALATSDIIDVVDV---------DAALARGGRRHRSGRSDGQWDDMLSSWAAQL 418 N+ RL AL D+I + D+ + + R S ++ + + A Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 419 LSE-GAQGLHAEARERLDRTLLEAALQLTQGRRAEAAARLGLGRNTVTRKL 468 GL+ ++ L+ AAL T+G + +AA LGL RNT+ +K+ Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKI 470
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.033 Identities = 10/50 (20%), Positives = 21/50 (42%) Query: 13 LAWLLLVVAVAAVGVALLLGWRAWQNYQATQLQAAQAQQQRWDGTQQMLE 62 L+ + VV V + L GW ++NY+ ++ + + L+ Sbjct: 118 LSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALK 167
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 195 bits (498), Expect = 5e-67 Identities = 64/160 (40%), Positives = 99/160 (61%), Gaps = 3/160 (1%) Query: 1 MSDEILNGAAAPADAAAGPAFTIEKIYVKDVSFESPNAPAVFNDANQPELQLNLNQKVQR 60 MS+E AA A P I++IYVKDVSFE+PN P +F +P+L +L+ + ++ Sbjct: 1 MSEENQVNAAD-TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQ 59 Query: 61 LNDNAFEVVLAVTLTCTA--GGKTAYVAEVQQAGVFGLVGLDPQAIDVLLGTQCPNILFP 118 + D+ +EV L +++ T G A++ EV+QAGVF + GL+ + L +QCPN+LFP Sbjct: 60 VGDDLYEVCLNISVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFP 119 Query: 119 YVRTLVSDLIQAGGFPPFYLQPINFEALYAETLRQRQNEG 158 Y R LVS L+ G FP L P+NF+AL+ + L++++ Sbjct: 120 YARELVSSLVNRGTFPALNLSPVNFDALFMDYLQRQEQAE 159
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 27.6 bits (61), Expect = 0.031 Identities = 20/94 (21%), Positives = 32/94 (34%), Gaps = 10/94 (10%) Query: 49 KASYAIAPNFHVFGDYSKQ--NADDNNNVFENTDSDFQQWGV-GVGFNHEIATSTDFVAR 105 K Y I + ++ AD +NV + D V G E A + + R Sbjct: 103 KLGYPITDDLDIYTRLGGMVWRADTKSNV-YGKNHDTGVSPVFAGGV--EYAITPEIATR 159 Query: 106 VAYRKL----DLDTPNINFDGYSVEAGLRNAFGE 135 + Y+ D T D + G+ FG+ Sbjct: 160 LEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQ 193
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.019 Identities = 19/97 (19%), Positives = 38/97 (39%), Gaps = 15/97 (15%) Query: 383 VHNLLRNAAQHADPGSEVTLQAAAVEGMLQLQVCNRGAPIAEPIAAHLFEPFVSGRADGN 442 V N +++ G ++ L+ G + L+V N G+ + + Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------------NTKEST 311 Query: 443 GLGLALVRE-IARAHGGHAR--YAHADGLTHFILELP 476 G GL VRE + +G A+ + G + ++ +P Sbjct: 312 GTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 465 bits (1198), Expect = e-164 Identities = 178/478 (37%), Positives = 257/478 (53%), Gaps = 37/478 (7%) Query: 2 ARILIIDDDAAFRTTLQATLRSLGHTAVAAENGPDGLARLSEGGIDMAFVDFRMPGMDGI 61 A IL+ DDDAA RT L L G+ N ++ G D+ D MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 AVLRARLDDAQARQVPLVMLTAHVSSGNTIEAMTLGAFDHLVKPVGRADIVEVVERALLS 121 +L R+ A+ +P+++++A + I+A GA+D+L KP +++ ++ RAL Sbjct: 64 DLLP-RIKKARPD-LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 122 RAEAQAAATDALSAPVEDDDALVGHSPAMRTVHKRIGLAAASDLPVLITGETGTGKELAA 181 + L +D LVG S AM+ +++ + +DL ++ITGE+GTGKEL A Sbjct: 122 PKRRPSK----LEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 182 RALHRASPRASAPFAAVNCAAIPLELMESELFGHRKGAFSGASSDRRGLIREADGGTLFL 241 RALH R + PF A+N AAIP +L+ESELFGH KGAF+GA + G +A+GGTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 242 DEIGDMPLPMQAKLLRFLQEGEVTPLGGSGPQKVDVRVLAATHRDLAACVADGRFRSDLR 301 DEIGDMP+ Q +LLR LQ+GE T +GG P + DVR++AAT++DL + G FR DL Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 302 YRLNVVPIELPPLRERGQDILLLAQHFLSANAA---RAQSLSPAAQERLLAHRWPGNVRE 358 YRLNVVP+ LPPLR+R +DI L +HF+ + A E + AH WPGNVRE Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 359 LRNVMQRSQVLVRGASIDAADLE----------------------------EALGEAGEA 390 L N+++R L I +E E A Sbjct: 358 LENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFA 417 Query: 391 PPNGASALTGTLPEAVAQLEKRMIQSALEQSQGNRAEAARRLGIHRQLLYRKLEEYGL 448 A +G +A++E +I +AL ++GN+ +AA LG++R L +K+ E G+ Sbjct: 418 SFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.5 bits (74), Expect = 0.003 Identities = 70/373 (18%), Positives = 127/373 (34%), Gaps = 18/373 (4%) Query: 30 PFLSVFLQSKGWSVAAIGTVMSVGGIAGMLATTPAGALVDATRRKRAVVVIGCLAILLAT 89 P L L A G ++++ + GAL D R R V+++ + Sbjct: 29 PGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGR-RPVLLVSLAGAAVDY 87 Query: 90 ALIWLQPTSSGVVAAQIASALAAA---GIGPALTGITLGLVHARGFDHQLARNQVANHAG 146 A++ P + +I + + A G + IT G AR F A G Sbjct: 88 AIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSA----CFGFG 143 Query: 147 NVLAAVLAGWLGWRYGFAAVFLLTAFFGALALVAVLAIPAAAIDHRAARGLASNNGGDAL 206 V VL G +G + A F A L + + + H+ R + L Sbjct: 144 MVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPES--HKGERRPLRREALNPL 200 Query: 207 SGWRVLLTCRPLALLAVTLGLFHLGNAAMLPLYGMAIVAAHAGDPSALTATTIVVAQATM 266 + +R +A L + L L+ + D + + + Sbjct: 201 ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHS 260 Query: 267 VVVALLAMRWIRVHGHWWVLLVAFMALPLRALVAASVIHGWGVFPVQILDGLGAGLQSVV 326 + A++ G L++ +A ++ A GW FP+ +L G + Sbjct: 261 LAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG----IG 316 Query: 327 VPALVARLLQGTGRVNVG--QGAVMTVQGVGAALSPAFGGWL-AHAFGYRIAFLTLGAIA 383 +PAL A L + G QG++ + + + + P + A + + + A Sbjct: 317 MPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAA 376 Query: 384 LLAVALWAGCRGM 396 L + L A RG+ Sbjct: 377 LYLLCLPALRRGL 389
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 139 bits (351), Expect = 1e-40 Identities = 79/362 (21%), Positives = 132/362 (36%), Gaps = 78/362 (21%) Query: 1 MKVLVTGGGGFLGQALCRGLRARGHEVV-----------SFQRGDYPVLQRLGVGQIRGD 49 MK LVTG GF+G + + L GH+VV S ++ +L + G + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 50 LADPQAVRHAFA--GIDAVFHNAAKAG---AWGSYDSYHQANVVGTQNVIEACRANGVPR 104 LAD + + FA + VF + + + + +Y +N+ G N++E CR N + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 105 LIYTSTPSVTHRATNPVEGLGADE-VPYGDDLRAA-----YAATKAIAERAVLAANDA-Q 157 L+Y S+ SV G + +P+ D YAATK E + Sbjct: 121 LLYASSSSV----------YGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 158 LATVALRPRLIWGP-GD-NHLLPRLAARARAGR-LRMVGDGGNLVDSTYIDNAAQAHFDA 214 L LR ++GP G + L + G+ + + G D TYID+ A+A Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRL 230 Query: 215 FEHLAVGAACA-------------GRAYFISNGEPLPMRELLNRLLAAVDAPAVTCSLSF 261 + + R Y I N P+ + + + L A+ A L Sbjct: 231 QDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPL 290 Query: 262 NTAYRIGAVCETLWPLLRLPGEVPLTRFLVEQLCTPHWYSMEPARRDFGYVPRISIEEGL 321 PG+V T + G+ P ++++G+ Sbjct: 291 Q------------------PGDVLET-----------SADTKALYEVIGFTPETTVKDGV 321 Query: 322 QR 323 + Sbjct: 322 KN 323
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 24.0 bits (52), Expect = 0.029 Identities = 5/20 (25%), Positives = 9/20 (45%) Query: 28 TNIAWILFVVFLILAVISMF 47 +AW++ V LA + Sbjct: 32 KKLAWVVAGVAGALATAGVV 51
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.029 Identities = 19/114 (16%), Positives = 38/114 (33%), Gaps = 10/114 (8%) Query: 30 VVNYEEGAENCVLNGDAGSEAFLSEMVGAQAHAGARAMAMESLYEYGSRAGFWRLHRLFT 89 + Y G E + + F E G + L G+ A + ++ Sbjct: 734 LHLYLAG-ERYFPSPEDEEIYFRPEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYS 792 Query: 90 ARNVPVTVFGVAQALASNP---DAVAAMQAAQWEIASHGLRWIDYQHVDEATER 140 VT+ + QAL ++P + Q W L ++++ E + + Sbjct: 793 VNTTFVTIADLVQALGADPGKSSPMLEGQVRDW------LNENGWEYLRETSGQ 840
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.8 bits (98), Expect = 3e-06 Identities = 28/132 (21%), Positives = 51/132 (38%), Gaps = 1/132 (0%) Query: 47 LTPIASDLHASAGMAGQAISISGLFAVVASLLIAPLSSRFN-RRHVLIALTGMMLLSLLL 105 L IA+D + + L + + + LS + +R +L + S++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 106 IANAHSFGMLMVARALLGITIGGFWALSTATVMRLMPEHAVPKALGIVFIGNAVAAAFAA 165 F +L++AR + G F AL V R +P+ KA G++ A+ Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 166 PLGSYLGASIGW 177 +G + I W Sbjct: 157 AIGGMIAHYIHW 168
>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature. Length = 591 Score = 32.0 bits (72), Expect = 0.006 Identities = 12/30 (40%), Positives = 18/30 (60%), Gaps = 3/30 (10%) Query: 56 GDGFWLIHEPDGRVHAIDACGRAAQAATLD 85 GD FWL+H+ +G +H + G+ A A D Sbjct: 155 GDDFWLLHDSNGILHLL---GKTAAARLSD 181
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 26.7 bits (59), Expect = 0.034 Identities = 6/27 (22%), Positives = 16/27 (59%) Query: 55 LPAHTRSLITLSMMIALGHDEEFKLHV 81 +PA R + +++++ +F++HV Sbjct: 138 MPARYRKNVLGAVLLSPSQSSDFEIHV 164
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 61.3 bits (149), Expect = 2e-16 Identities = 24/78 (30%), Positives = 43/78 (55%) Query: 4 DDLVRFTSEALLLCLKVSLPVVGVAALAGLLIAFIQAVMSLQDASISFALKLVVVVAAIA 63 DDLV ++AL L L +S VA + GLL+ Q V LQ+ ++ F +KL+ V + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VTAPWGASAIMQFGQALM 81 + + W ++ +G+ ++ Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 246 bits (630), Expect = 2e-85 Identities = 80/219 (36%), Positives = 130/219 (59%), Gaps = 8/219 (3%) Query: 3 MPDVGSLLLVVIMLGLLPFAAMVVTSYTKIVVVLGLLRNAIGVQQVPPNMVLNGVALLVS 62 M + SL+ ++ LLPF T + K +V ++RNA+G+QQ+P NM LNGVALL+S Sbjct: 1 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60 Query: 63 CFVMAPVGMEAFKA-AQNYGAGSDNSRVVVLLDACREPFRQFLLKHTREREKAFFMRSAQ 121 FVM P+ +A+ +D S + +D + +R +L+K++ FF + Sbjct: 61 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120 Query: 122 QIWPKDKAAT-------LKSDDLLVLAPAFTLSELTEAFRIGFLLYLVFIVIDLVVANAL 174 + ++ T ++ + L PA+ LSE+ AF+IGF LYL F+V+DLVV++ L Sbjct: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180 Query: 175 MAMGLSQVTPTNVAIPFKLLLFVAMDGWSMLIHGLVLSY 213 +A+G+ ++P ++ P KL+LFVA+DGW++L GL+L Y Sbjct: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 68.5 bits (167), Expect = 2e-15 Identities = 42/177 (23%), Positives = 75/177 (42%), Gaps = 15/177 (8%) Query: 144 PAPLPVWLAALRVNTRLRIGERTASAALLQSLRPGDVLLHCTASAAATSGEVLWGIAGGA 203 PA LR R IG +LL + GDVLL T+ A G Sbjct: 138 PAVGGGRPKMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTSRAEVYCYAKKLG----- 192 Query: 204 VLRAPVRLNLQQMILEATPTMQHDTFE---PEVAQSASNVAELELPVQLEVDQLALSLST 260 ++ I+ T +QH E E A++ + +L + ++ + + ++L+ Sbjct: 193 -----HFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYRKNVTLAE 247 Query: 261 LSGLQPGQILELSVPVDQADIRLVVYGQTIGIGRLVTVGEHLGVQILS-MSESTHAD 316 L + Q+L L + ++ ++ G +G G LV + + LGV+I +SES + + Sbjct: 248 LEAMGQQQLLSLPTNAEL-NVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESGNGE 303
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 326 bits (838), Expect = e-113 Identities = 113/345 (32%), Positives = 190/345 (55%), Gaps = 2/345 (0%) Query: 1 MSEEKTEKPTEKKLRDARRDGEVPVSPDVTAAAVLFGALMVMKSAGDYFSDHMRALMTIG 60 MS EKTE+PT KK+RDAR+ G+V S +V + A++ ++ DY+ +H LM I Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 61 FDFPENTRDATAINRALGHIGIQGLVLMLPLLVACLVAGVAGGAFQTGLNASLKPVAPKF 120 + + A++ + ++ ++ L PLL + +A Q G S + + P Sbjct: 61 AE-QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDI 119 Query: 121 DSLNPATGVKKLFSLRSLINLLKLIIKAILIGVVLWAGIRILMPMIIGLAYQTPPDIAQI 180 +NP G K++FS++SL+ LK I+K +L+ +++W I+ + ++ L I + Sbjct: 120 KKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPL 179 Query: 181 AWRTLGMLFALGVLLFVLVGAADWSVQHWLFIRDKRMSKDEQKREVKESEGDPEIKGKRK 240 + L L + + FV++ AD++ +++ +I++ +MSKDE KRE KE EG PEIK KR+ Sbjct: 180 LGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRR 239 Query: 241 EFAKQMVFGDPRERVAKAKVMVVNPTHYAVALAYEPDDFGLPQVVAKGVDDGALELRAFA 300 +F +++ + RE V ++ V+V NPTH A+ + Y+ + LP V K D +R A Sbjct: 240 QFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIA 299 Query: 301 HNQGIPIVANPPLARALY-QVELGDAVPEPLFETVAVVLRWVDEL 344 +G+PI+ PLARALY + +P E A VLRW++ Sbjct: 300 EEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 38.7 bits (90), Expect = 5e-05 Identities = 46/235 (19%), Positives = 73/235 (31%), Gaps = 52/235 (22%) Query: 229 YNDLKQAY---GYPSYQTMVGAPGQQRRLDGSGSTIAILIGSDVLDSDIATMFDHEHFSR 285 Y +KQ P M+ AP + G G +A VLD+ DH Sbjct: 10 YQVIKQEQQVNEIPRGVEMIQAPAVWNQTRGRGVKVA------VLDTGC--DADHPDLK- 60 Query: 286 YAGNHANPTLYARRYVAGAKPGVQDGNR-----AAAREATLDVDMALGGAPGAHVLLYVI 340 G +D N A AT + + +G AP A +L+ + Sbjct: 61 ---ARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKV 117 Query: 341 PDL----SIDSILAGYRQIVQDNEADVVSSSFGLCEQVFTAAYNGNDATSILGLFDSVFK 396 + D I+ G ++ D++S S G G + L K Sbjct: 118 LNKQGSGQYDWIIQGIYYAIEQK-VDIISMSLG-----------GPEDVPEL---HEAVK 162 Query: 397 QGNAQGISFVASSGDNAGLECPDTQYLVEGKSGRYIPSVEWPAADAHVTAVGGGN 451 + A I + ++G+ EG + +P V +VG N Sbjct: 163 KAVASQILVMCAAGN-------------EGDGDDRTDELGYPGCYNEVISVGAIN 204
>PF06776#Invasion associated locus B Length = 214 Score = 32.2 bits (73), Expect = 0.001 Identities = 13/51 (25%), Positives = 20/51 (39%) Query: 8 LLPLALTLAIAACSKPAENTAAPAAETPAAATAPADAAAAPAPAPAAAAST 58 + P L+ +A+C + A A A A A + + A A A S Sbjct: 29 MGPAELSPMLASCRRLARRNGARLMLAGAMAIALSFGWSDRADAQGAVRSV 79
>adhesinb#Adhesin B signature. Length = 310 Score = 29.8 bits (67), Expect = 0.001 Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 1 MKNARIGLVALTMALGLTACSGKPSSDSAKDA 32 MK R ++ L +GL ACS + SS + Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSS 32
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.4 bits (58), Expect = 0.047 Identities = 10/50 (20%), Positives = 18/50 (36%), Gaps = 3/50 (6%) Query: 15 AQLLEELRKLEQEEAQLKYAQTLEAFDQVIEVLTQFG---SRFNAKQKSQ 61 Q EEL L + A + +++ + L + G + K K Sbjct: 405 LQNEEELNYLYSVLTNINNADNYDEIEEIKKELIETGYIKFKKIYKSKKS 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 32/119 (26%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Query: 2 RILVIEDNSDIAANLGDYLEDRGHTVDFAADGVTGLHLAVVHEFDAIVLDLNLPGMDGIE 61 ILV +D++ I L L G+ V ++ T + D +V D+ +P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VCRKLRNEARKQTPVLMLTARDSLDNKLAGFDSGADDYLIKPFALQE-VEVRLNALSRR 119 + +++ +AR PVL+++A+++ + + GA DYL KPF L E + + AL+ Sbjct: 65 LLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 330 bits (848), Expect = e-116 Identities = 129/282 (45%), Positives = 176/282 (62%), Gaps = 1/282 (0%) Query: 1 MAFLDQHPGLGFPAAAGLGLLIGSFLNVVILRLPKRMEWQWRRDAREILELPDI-YEPPP 59 + P L F L+IGSFLNVVI RLP +E +W+ + R D + PP Sbjct: 5 LELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEPP 64 Query: 60 PGIVVEPSHDPVTGDKLKWWENIPVLSWAMLRGKSRYSGKPISIQYPLVELLTSILCVAS 119 ++V S P + ENIP+LSW LRG+ R PIS +YPLVELLT++L VA Sbjct: 65 YNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVAV 124 Query: 120 VWRFGFGWQGFGAIVLSCFLVAMSGIDLRHKLLPDQLTLPLMWLGLVGSMDNLYMPAKPA 179 GW A++L+ LVA++ IDL LLPDQLTLPL+W GL+ ++ ++ A Sbjct: 125 AMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDA 184 Query: 180 LLGAAVGYVSLWTVWWLFKQLTGKEGMGHGDFKLLAALGAWCGLKGILPIILISSLVGAI 239 ++GA GY+ LW+++W FK LTGKEGMG+GDFKLLAALGAW G + + ++L+SSLVGA Sbjct: 185 VIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGAF 244 Query: 240 LGSIWLVAKGRDRATPIPFGPYLAIAGWVVFFWGNDLVDGYL 281 +G ++ + ++ PIPFGPYLAIAGW+ WG+ + YL Sbjct: 245 MGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 45.3 bits (107), Expect = 7e-09 Identities = 16/46 (34%), Positives = 29/46 (63%) Query: 1 MKKQQGFTLIELMIVIAIIAILAAIALPQYQNYVAKSQVTAGLAEL 46 KQ+GFTL+E+M+VI II +LA++ +P K+ ++++ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 43.0 bits (101), Expect = 4e-08 Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 7/44 (15%) Query: 12 KGFTLIELMIVIAIIAVLASIAIPQY-------QIYVAKSQVAA 48 +GFTL+E+M+VI II VLAS+ +P A S + A Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVA 51
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 513 bits (1322), Expect = 0.0 Identities = 169/474 (35%), Positives = 256/474 (54%), Gaps = 17/474 (3%) Query: 9 SALVVDDERDIRELLVLTLGRMGLRISTAANLAEARELLANNPYDLCLTDMRLPDGNGIE 68 + LV DD+ IR +L L R G + +N A +A DL +TD+ +PD N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 69 LVTEIAKHYPQTPVAMITAFGSMDLAVEALKAGAFDFVSKPVDIGVLRGLVKHALELNNR 128 L+ I K P PV +++A + A++A + GA+D++ KP D+ L G++ AL R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 129 DRPAPPPPPPEQASRLLGDSSAMEILRATISKVARSQAPVYIVGESGVGKELVARTIHEQ 188 RP+ + L+G S+AM+ + ++++ ++ + I GESG GKELVAR +H+ Sbjct: 125 -RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 189 GARAAGPFVPVNCGAIPAELMESEFFGHKKGSFTGAHADKPGLFQAAHGGTLFLDEVAEL 248 G R GPFV +N AIP +L+ESE FGH+KG+FTGA G F+ A GGTLFLDE+ ++ Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 249 PLQMQVKLLRAIQEKSVRPVGASSESLVDVRILSATHKDLGDLVSDGRFRHDLYYRINVI 308 P+ Q +LLR +Q+ VG + DVRI++AT+KDL ++ G FR DLYYR+NV+ Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 309 ELRVPPLRERGGDLPQLAAAIIARLAHSHGRPIPLLTQSALDALNHYGFPGNVRELENIL 368 LR+PPLR+R D+P L + + A G + Q AL+ + + +PGNVRELEN++ Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 369 ERALALAEDDQISATDLRLPAH---------------GGHRLAAPPGGAAAEPREAVVDI 413 R AL D I+ + G ++ + + D Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 414 DPASAALPSYIEQLERAAIQKALEENRWNKTKTAAQLGITFRALRYKLKKLGME 467 P S + ++E I AL R N+ K A LG+ LR K+++LG+ Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 7e-04 Identities = 16/95 (16%), Positives = 34/95 (35%), Gaps = 16/95 (16%) Query: 431 ILTALVHNALKYG-RVMDEPARVKLHVERLERKAVIDVIDRGPGIPDAVAAQLFRPFYTT 489 ++ LV N +K+G + + ++ L + ++V + G Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK------------N 306 Query: 490 SEHGTGLGLYIAQELCRA---NQAQLDYVSVPGGG 521 ++ TG GL +E + +AQ+ G Sbjct: 307 TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV 341
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 30.9 bits (69), Expect = 0.005 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 3/45 (6%) Query: 185 PYTRDAYEVEWKTIEELAARAQFSAEPADRSSDANGYAELYPDPI 229 P+ D Y V W T+E+ R F E D AE P PI Sbjct: 420 PFLHDGYAVSWNTVEDSIIRTGFQGESG---HDIKITAENTPLPI 461
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 27.9 bits (62), Expect = 0.036 Identities = 14/104 (13%), Positives = 33/104 (31%), Gaps = 2/104 (1%) Query: 118 QTRLERELAQARQRADAQQRERDALRLAAAEHQALQVRWTDDVHALEGVRTELSAARTEL 177 + Q+ ++ R + + E L D + V E T L Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190 Query: 178 VEERQRREHAEADTLRATVRLSTLEQ--LLAQLRPAHSVGELEN 219 ++E+ + + E+ +LA++ ++ +E Sbjct: 191 IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.5 bits (66), Expect = 0.005 Identities = 28/123 (22%), Positives = 42/123 (34%), Gaps = 13/123 (10%) Query: 35 RWGG--GWVTIYTAYTSLSSNATGSSAQYN-NGNSRTPMTRQLGARASIYTAGGNGNLTY 91 +W +T +T S A + QYN +G + + L + I GN Sbjct: 367 QWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAM 426 Query: 92 SWFVSGSSQVSNVSIGPSGPHCDVSVTATMNQTGSVTVGCTVSDGQSSTTAYATNYYDYF 151 ++ S + I + P S+ N + VG V S T N F Sbjct: 427 L--LTALSSSTKNDI-LATP----SIVTLDNMEATFNVGQEVPVLTGSQTTSGDN---IF 476 Query: 152 NTV 154 NTV Sbjct: 477 NTV 479
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 35.3 bits (81), Expect = 0.002 Identities = 25/103 (24%), Positives = 42/103 (40%), Gaps = 13/103 (12%) Query: 802 LVQGIRSKL---GAAGDAIASVGS---------GVVDRFKGLLGIHSPSRVFAQLGDFTM 849 + Q L AA IAS + + D+FK I S+ F +LG + Sbjct: 292 IAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADKFKRANKIEEYSQRFKKLG-YDG 350 Query: 850 QGLTVGLQRGQGAPVQAVAALGNRMRAVSAGLALATATAPVAA 892 L + GA ++ + + +VS+G++ A T+ V A Sbjct: 351 DSLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVGA 393
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 1e-13 Identities = 27/119 (22%), Positives = 52/119 (43%), Gaps = 7/119 (5%) Query: 9 VLVVEDEPLVRQVAQLMLECAGFTVVVAEDAHRALEVLEMESAVCLIVSDVQMPGYLDGL 68 +LV +D+ +R V L AG+ V + +A + L+V+DV MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-AGDGDLVVTDVVMPD-ENAF 63 Query: 69 DLIKHLRLEGVQTPAILTSGRIHPQALPAET-----SFLPKPYTLAKLLEVVHERLPKT 122 DL+ ++ P ++ S + + +LPKP+ L +L+ ++ L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 3e-14 Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 2/84 (2%) Query: 5 QQQQILLVEDDRALQELTTMLLEERGYSVIAASNALDALQIIHDCSSLALLITDVYMPGD 64 IL+ +DD A++ + L GY V SNA + I L++TDV MP Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVMPD- 59 Query: 65 MSGYELVCGLRKSGNEMPAVLMSG 88 + ++L+ ++K+ ++P ++MS Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSA 83
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 0.002 Identities = 15/89 (16%), Positives = 34/89 (38%), Gaps = 10/89 (11%) Query: 56 EETAQSARSSLPKPREILEVLDQY----VIGQLRAKRTLAVAVYNHYKRIESRSKNDDVE 111 + + + A LPKP ++ E++ + R + + S + + Sbjct: 92 KASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR 151 Query: 112 LAK------SNILLVGPTGSGKTLLAETL 134 + +++ G +G+GK L+A L Sbjct: 152 VLARLMQTDLTLMITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 0.003 Identities = 32/124 (25%), Positives = 51/124 (41%), Gaps = 21/124 (16%) Query: 333 ERILEYLAVQSRVKQMKGPILCLVGPPGVGKTSLGQSIAKATNRK---FVRMSLGGIRD- 388 + E V +R+ Q ++ + G G GK + +++ R+ FV +++ I Sbjct: 144 AAMQEIYRVLARLMQTDLTLM-ITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRD 202 Query: 389 --EAEIRGHRRTY----VGSMPGRLVQNLNKVGSKNPLFLLDEIDKMSMDFRGDPSSALL 442 E+E+ GH + GR Q LFL DEI M MD + + LL Sbjct: 203 LIESELFGHEKGAFTGAQTRSTGRFEQ-----AEGGTLFL-DEIGDMPMDAQ----TRLL 252 Query: 443 EVLD 446 VL Sbjct: 253 RVLQ 256
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 2e-38 Identities = 54/88 (61%), Positives = 67/88 (76%) Query: 2 NKTELIDGVAAAADISKAEAGRAVDAVVSEITKALKKGDAVTLVGFGTFQVRERAERTGR 61 NK +LI VA A +++K ++ AVDAV S ++ L KG+ V L+GFG F+VRERA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPKTGDSIKIAASKNPAFKAGKALKDAV 89 NP+TG+ IKI ASK PAFKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 29.2 bits (65), Expect = 0.004 Identities = 11/30 (36%), Positives = 17/30 (56%) Query: 76 QGLAQDGYRIVMNCREHAGQTVFHIHLHLL 105 QG+ QD RI+ + +H Q V+ L L+ Sbjct: 298 QGMIQDKDRILTSVLKHIKQAVYETLLDLI 327
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.003 Identities = 14/50 (28%), Positives = 21/50 (42%), Gaps = 1/50 (2%) Query: 114 LLADEINRAPPRTQSSLLEAMAEQQVTLDGVTHALPEPFFVIATQNPVDL 163 L DEI P Q+ LL + + + T G + ++A N DL Sbjct: 235 LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATN-KDL 283
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 58.7 bits (142), Expect = 1e-11 Identities = 85/368 (23%), Positives = 134/368 (36%), Gaps = 22/368 (5%) Query: 15 ALLALTIGAFGIGTTEFVIMGLLQQVAADLGVSLSAAGLLISGYALGVFVGAPVLTLASA 74 L + + A GIG V+ GLL+ + + G+L++ YAL F APVL S Sbjct: 10 ILSTVALDAVGIGLIMPVLPGLLRDLVHS-NDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 75 RLPRKAVLVGLMLIFTVGNVACALAPDYTSLMVARVLTSLAHGTFFGVGAVVATSLVPAE 134 R R+ VL+ + V A AP L + R++ + T GA +A + + Sbjct: 69 RFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DITDGD 127 Query: 135 RRASAISLMFAGLTVATLLGVPAGAWLGLQLGWRATFWAVAAIGVLATSAVAVWVPAAAG 194 RA M A + G G +G A F+A AA+ L +P + Sbjct: 128 ERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186 Query: 195 AATPVSWRQEVAVLQRGQVLLALAITVVGYAGVFAVFAYIQ-----PLLLQVT------G 243 R+ + L A + A + AVF +Q P L V Sbjct: 187 GERRPLRREALNPL----ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFH 242 Query: 244 FAQSTVSPVLLVFGV-GMIVGNLLGGRLADR-RPTAALLGSLAALVVVLGALGCVLHSKA 301 + +T+ L FG+ + ++ G +A R AL+ + A L Sbjct: 243 WDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWM 302 Query: 302 AM--VTFVGLLGVAAFATVAPLQLRVLEHARGAGQNLASSLNIAAFNLGNALGAWLGGVV 359 A + + G+ A A L +V E +G Q ++L +G L + Sbjct: 303 AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 360 IATQAGLV 367 I T G Sbjct: 363 ITTWNGWA 370
>INTIMIN#Intimin signature. Length = 939 Score = 30.0 bits (67), Expect = 0.007 Identities = 23/109 (21%), Positives = 38/109 (34%), Gaps = 2/109 (1%) Query: 11 VVAASMSAPVSAQVFDRARLRAAATGQTVVVDRASFRLIPGAVVRLADATRGAAA--TQT 68 V S V+A+ +DR + T+ V + V A A T+ Sbjct: 518 VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 69 LTSTQTRTNAPVARVDRYAIYLDTSGAADAVARTTRSEPSATVVAALET 117 +T T T VA+ + + SG A A + + S L++ Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKS 626
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 121 bits (304), Expect = 1e-32 Identities = 76/379 (20%), Positives = 111/379 (29%), Gaps = 120/379 (31%) Query: 2 AVIDDGLEIAHEDLVDNIVAGGSHNFLNGSNDPTPPADEIDNDHGTAVAGIIAAPGWNGL 61 AV+D G + H DL I+ G + + DP D N HGT VAG IAA N Sbjct: 46 AVLDTGCDADHPDLKARIIGGRNFTD-DDEGDPEIFKD--YNGHGTHVAGTIAA-TENEN 101 Query: 62 GGRGVAPEANVAGFNALSILDGSKQYVDIRYSWGDGAEARAMDVYNNSFGISTAVYPFSD 121 G GVAPEA++ L+ GS QY I A + +D+ + S G V + Sbjct: 102 GVVGVAPEADLLIIKVLN-KQGSGQYDWIIQGI-YYAIEQKVDIISMSLGGPEDVPELHE 159 Query: 122 LDEQRSLEKLMRAQRGGKGGIYVKAAGNDFNTLLDVDAQGKLIDRCSDQTRQLGVACSSA 181 + +A + + AAGN+ G DR Sbjct: 160 A--------VKKAVA--SQILVMCAAGNE----------GDGDDRTD------------- 186 Query: 182 NIDNLNSLTTMIVVGAVNANGVRASYSSPGSALWVSGLSGEFGFQRRFDPHPETYSPLYT 241 + +I VGA+N + + +S+ + Sbjct: 187 ELGYPGCYNEVISVGAINFDRHASEFSNSNN---------------------------EV 219 Query: 242 LLAAQGPQPFFSPAIVTTDLSGCAAGNNRDRTRAPQNALDTSHSKIDASCNYSARMNGTS 301 L A G + + + G A +GTS Sbjct: 220 DLVAPG-------EDILSTVPG----------------------------GKYATFSGTS 244 Query: 302 ASAPTVAGVAALMLGANPQLTLRDVKYILATTAVQVDPHQAKAFYKDAVIEPAWITNAAG 361 + P VAG AL+ RD+ + Sbjct: 245 MATPHVAGALALIKQLANASFERDLTEPELYAQLIKR-----------------TIPLGN 287 Query: 362 HRFSNWYGFGLVDAAAAVE 380 G GL+ A E Sbjct: 288 SPK--MEGNGLLYLTAVEE 304
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 126 bits (317), Expect = 3e-34 Identities = 77/385 (20%), Positives = 112/385 (29%), Gaps = 111/385 (28%) Query: 76 DIRGRGVRVGVVDDGLELGHEDLADNILPNGSHNFGDGSHDTTPIDPSNGHGTSVAGIIG 135 RGRGV+V V+D G + H DL I+ + D D NGHGT VAG I Sbjct: 37 QTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEG-DPEIFKDYNGHGTHVAGTIA 95 Query: 136 AVGWNGRGGRGVAPEVQLAGFDVFARDSSVTDASIRYAWGDGPEARNIDVFNNSWGSVAP 195 A N G GVAPE L V + S I + +D+ + S G Sbjct: 96 ATE-NENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGI-YYAIEQKVDIISMSLGG--- 150 Query: 196 FYFDFSVEDQRTWQALMGSTRGGLGGIYVKSAGNSFLRFLEPDENGNPVNVCSEQSRALQ 255 D + +A+ + + +AGN DE G P Sbjct: 151 -PEDVPELHEAVKKAVAS------QILVMCAAGNEGDGDDRTDELGYP------------ 191 Query: 256 VGCSLANIDPFANLPGTIVVASLNAKGTRASYSSTGSALWVSGLGGEFGRQRKFYPDAAS 315 I V ++N + +S++ + + + G Sbjct: 192 -----------GCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGE-------------- 226 Query: 316 TFFPDSAPYAYDPAIVTTDLSGCTAGENVEDPDVVYNALDGSKSKIDASCNYNAIMNGTS 375 I++T G A +GTS Sbjct: 227 -------------DILSTVPGGKY-----------------------------ATFSGTS 244 Query: 376 AAAPTVSGVAALILGANASLSARDVKYILATTARQIDPWQPRVVYQGSVIDPGWITNAAG 435 A P V+G ALI + RD +Y + + N+ Sbjct: 245 MATPHVAGALALIKQLANASFERD--------------LTEPELYAQLIKRTIPLGNS-- 288 Query: 436 HRFSNWYGFGLADAAAAVYKARYFT 460 G GL A +R F Sbjct: 289 ---PKMEGNGLLYLTAVEELSRIFD 310
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.019 Identities = 24/121 (19%), Positives = 46/121 (38%), Gaps = 12/121 (9%) Query: 858 GTDTVTERPPANGLVVTGRAASLDAIDWISLARGSSGDADMPPLPGQPAVPSKDPMPLQQ 917 G +V P+N L++TGRAA + + I ++GD + +P A + + + Sbjct: 154 GVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADVVKLVTE 213 Query: 918 VDVQADRLLMIGGVFPQTRLRLRPTRDTVAVTLDGP--------SLAGQLTVPNADGATV 969 ++ + + G + R T AV + G ++ QL A Sbjct: 214 LNKDTSKSALPGSMVANVVADER----TNAVLVSGEPNSRQRIIAMIKQLDRQQATQGNT 269 Query: 970 Q 970 + Sbjct: 270 K 270
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 76.4 bits (188), Expect = 2e-16 Identities = 51/202 (25%), Positives = 86/202 (42%), Gaps = 30/202 (14%) Query: 424 IMGHVDHGKTSLLDYI-----RRTKIASGEAG-------------GITQHIGAYHVETGR 465 ++ HVD GKT+L + + T++ S + G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 466 GVISFLDTPGHAAFTSMRARGAKITDIVVLVVAADDGVMPQTKEAVAHAKAAGVPLIVAV 525 ++ +DTPGH F + R + D +L+++A DGV QT+ + G+P I + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 526 NKIDKTGADPLRV----KNELLAENVVAEE-------FGGDTQFIEVSAKLGTGVDTLLD 574 NKID+ G D V K +L AE V+ ++ + E + G D LL+ Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 575 AISLQAEVLELKAVAEGRASGT 596 + + LE + + + Sbjct: 188 KY-MSGKSLEALELEQEESIRF 208
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 71.2 bits (174), Expect = 8e-17 Identities = 41/196 (20%), Positives = 84/196 (42%), Gaps = 3/196 (1%) Query: 10 SAALSGRVVLITGAAGGLGAAAAQACAAAGATVVLLGRKVRPLERIYDAVAALGDEPLLY 69 + + G++ ITGAA G+G A A+ A+ GA + + LE++ ++ A + Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 70 PLDLAGATPDDYATLAQRLQTELGGLHGLLHCAADFSGLTPTELVLPTDFARTLHVDLTA 129 P D+ + R++ E+G + L++ A + ++ T V+ T Sbjct: 63 PADV--RDSAAIDEITARIEREMGPIDILVNVAGVLR-PGLIHSLSDEEWEATFSVNSTG 119 Query: 130 RAWLTQACLPLLRQQDDAAVVFVVDDPARVGQAYWGAYGAAQHAQRGLIATLHHETAAGP 189 +++ + + ++V V +PA V + AY +++ A L E A Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 190 VRVSGLQPGPMRTALR 205 +R + + PG T ++ Sbjct: 180 IRCNIVSPGSTETDMQ 195
>PF06580#Sensor histidine kinase Length = 349 Score = 181 bits (460), Expect = 2e-56 Identities = 82/334 (24%), Positives = 139/334 (41%), Gaps = 42/334 (12%) Query: 41 IGWISFGITSFMTQWTA------------LLTLAGLYVFRHHLR---NARPVMIAKVTLA 85 IGW + +T F ++L GL V H R + + + Sbjct: 18 IGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGL-VLTHAYRSFIKRQGWLKLNMGQI 76 Query: 86 LLLIAAALVLFIAMAVV---------GGAWSMGTRNWLELLLRTEGIALTVGLLGMWA-F 135 +L + A V+ + V + L L L I V + MW+ Sbjct: 77 ILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLAL--SIIFNVVVVTFMWSLL 134 Query: 136 HTHWR-----------ARQYAIRAKQFELEALRARIQPHFLFNTLNTGAALVRLNPARAE 184 + W + A A++ +L AL+A+I PHF+FN LN AL+ +P +A Sbjct: 135 YFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAR 194 Query: 185 RLLMDLAELFRATLAG--PEHILLSKELDIAKHYLDIEQIRFGERLSIVWKVPDEIPPVT 242 +L L+EL R +L + L+ EL + YL + I+F +RL ++ I V Sbjct: 195 EMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQ 254 Query: 243 VPSLSIQPLVENAIRHGVELRSEVSQIVVEVRQTSETIVVEVSNPLPPDKTTARTGHQVG 302 VP + +Q LVEN I+HG+ + +I+++ + + T+ +EV N + G Sbjct: 255 VPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTG 314 Query: 303 LAAVRARLHDL-DSRMGLQTTTQGNQFLATLHAP 335 L VR RL L + ++ + + + A + P Sbjct: 315 LQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.9 bits (80), Expect = 6e-05 Identities = 10/28 (35%), Positives = 20/28 (71%) Query: 12 QLGFSLIEMMVTIIVLAIVMAIAFPNFT 39 Q GF+L+E+MV I+++ ++ ++ PN Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLM 34
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.2 bits (68), Expect = 0.002 Identities = 7/20 (35%), Positives = 16/20 (80%) Query: 10 RRQAGVSLIEVLISVVILGI 29 +Q G +L+E+++ +VI+G+ Sbjct: 5 DKQRGFTLLEIMVVIVIIGV 24
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.9 bits (67), Expect = 0.007 Identities = 11/30 (36%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 9 KPVRGFTLIELLISLV-LGLLVTLAAIGLF 37 RGFTL+E+++ +V +G+L +L L Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLM 34
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 46.0 bits (109), Expect = 3e-09 Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 1 MKAVGKRRMSAGFTLIELMIVVAVIAVLAGIAMYNYQAAVVRAKRSAATSCLQSGAQYME 60 M+A K+R GFTL+E+M+V+ +I VLA + + N +A + A S + + ++ Sbjct: 1 MRATDKQR---GFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALD 57 Query: 61 RY 62 Y Sbjct: 58 MY 59
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 27.0 bits (59), Expect = 0.007 Identities = 20/66 (30%), Positives = 31/66 (46%), Gaps = 3/66 (4%) Query: 8 IYALNPELDSPDEVLRRLAVSDCADATVGRGRP-GHVALAFSRE--ASDRDAAVTLAAAQ 64 I A +P + E L ++D V + +P G VAL E A D A T+ AQ Sbjct: 292 INAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQ 351 Query: 65 RAQVLP 70 + +++P Sbjct: 352 KGEIMP 357
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.036 Identities = 35/171 (20%), Positives = 65/171 (38%), Gaps = 15/171 (8%) Query: 1336 NNVVLNDQLTLVGSNDLALNGSIGGTGSLIKNGATTLSLTANNS---YSGGTSLT---AG 1389 +V+ D + + + S G S I G +L++ + + G S+T +G Sbjct: 331 KDVLNKDSAGSLIGSKTDYSWSSNGKTSTITGGEKSLNVDLADGKDKPNHGKSVTFEGSG 390 Query: 1390 TIAVGADNALGTGGLSVLGNSVLSNAVAVALGNDIA-LGAALTVDNAADMLASGAISGSG 1448 T+ + + G GGL G+ + ++ GA ++V + Sbjct: 391 TLTLNNNIDQGAGGLFFEGDYEVK-----GTSDNTTWKGAGVSVAEGKTVTWKVHNPQYD 445 Query: 1449 SLIKTGLGTLTLSGNNSYTGPLAIQAGTVVASTSASLGNA---STVDVAAG 1496 L K G GTL + G G L + GTV+ + ++V + +G Sbjct: 446 RLAKIGKGTLIVEGTGDNKGSLKVGDGTVILKQQTNGSGQHAFASVGIVSG 496
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 1e-25 Identities = 28/153 (18%), Positives = 61/153 (39%) Query: 5 APVVYLIDDDASMRAALEDLFASVGLQVYAFGSTDQFLAHRLHEAPACLVLDIRMPGQSG 64 + + DDDA++R L + G V + +V D+ MP ++ Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 65 MEFHRRMVDSGFALPTIFITGHGDIAMSVEAMKNGAIEFLTKPFRDQALLDAIQDGIRRD 124 + R+ + LP + ++ +++A + GA ++L KPF L+ I + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 125 RVRRQNEAVAAELRARWESLSSGEQDVTRLVVQ 157 + R ++ S+ Q++ R++ + Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 642 bits (1657), Expect = 0.0 Identities = 235/1034 (22%), Positives = 427/1034 (41%), Gaps = 43/1034 (4%) Query: 11 QRRGIVWLVFVLIALYGTWSWTQLPVEAYPDIADVTSQVVTQVPGLGAEEVEQQITVPLE 70 +R W++ +++ + G + QLPV YP IA V PG A+ V+ +T +E Sbjct: 7 RRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIE 66 Query: 71 RALMGTPGLHVLRSRSLFA-LSLITLVFDDGTEGYFARQRVLERIQAVT--LPYGA-IPG 126 + + G L + S S A ITL F GT+ A+ +V ++Q T LP G Sbjct: 67 QNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQG 126 Query: 127 LDPYTSPTGEIYRYTLES--KTRSLRELSDLQFWTVIPRLQKVPGVADVTNFGGLTTQFS 184 + S + + S + ++SD V L ++ GV DV FG Sbjct: 127 ISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA-QYAMR 185 Query: 185 LALEPDRLTRYGVSLQQVKSAITSNNAD------GGGSVMDRGEQSYVIRGIGLLHSLQD 238 + L+ D L +Y ++ V + + N GG + + + I + ++ Sbjct: 186 IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEE 245 Query: 239 IGNVVVSSG-NGVPVLVKDLGEVRYDNVERRGILGKDGNPDTIEGIALLLKDSNPSVALQ 297 G V + +G V +KD+ V I +G P L +N + Sbjct: 246 FGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKP-AAGLGIKLATGANALDTAK 304 Query: 298 GIHSAVEELNNSALPKDVKVVPYLDRTALIDATMHTVSATLTEGMLLVCVVLLIFLGSPR 357 I + + EL P+ +KV+ D T + ++H V TL E ++LV +V+ +FL + R Sbjct: 305 AIKAKLAELQPF-FPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 358 AAAIVSLTIPLSLLIAFIVMHHLKIPANLLSLG--AIDFGILVDGAVVLVENVLRLREEN 415 A I ++ +P+ LL F ++ N L++ + G+LVD A+V+VENV R+ E+ Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 416 SQRALTARDAIDATLQVARPIFFGMAVIGCAYLPLLAFERIEYKLFSPMAYAVGAALIGA 475 A + Q+ + V+ ++P+ F ++ + + +A+ + Sbjct: 424 KLPPKEA--TEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 476 LLVALALIPGLAWLAFRKPRKMLH-----------NRVLEELGQRYRAVLERSVGRRGWL 524 +LVAL L P L KP H N + Y + + +G G Sbjct: 482 VLVALILTPALCAT-LLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 525 LACAALALCVLALLGGSIGRDFLPYIDEGSLWLQVQMPPGITLDKAATMANALRKATL-- 582 L AL + + +L + FLP D+G +Q+P G T ++ + + + L Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 583 EFPEVSYVVTQTGRNDDGTDYWTPSHIEASVGLRPYKEWP-AGMDKQALIAALGARYARM 641 E V V T G + G + A V L+P++E +A+I ++ Sbjct: 601 EKANVESVFTVNGFSFSGQ---AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 642 PGYTVSMMQPMIDGVQDKLSGAHSDLTVKVFGDDLQQVRGVADQVAFALHKVPGA-ADIA 700 V +G +L + G + +Q+ + P + + Sbjct: 658 RDGFVIPFNMPAIVELGTATGFDFEL-IDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 701 VDVEPPLPNLQVRFDREAAARYGINAADVSDLISTGIGGSPIGQMYLGQKSYDLTVRFPQ 760 + ++ D+E A G++ +D++ IST +GG+ + + L V+ Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 761 RYRNDPQAIGALRLRTAAGAEIPLSAVANIATTSGQSVIVREMGRRNIIVRLNVRGRDLS 820 ++R P+ + L +R+A G +P SA G + R G ++ ++ Sbjct: 777 KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP---G 833 Query: 821 SFLSDAQATLARQVHLDPQHMQLVWGGQFENLQRAQARLLVVLPTTLCIMFVLLFGAFGN 880 + DA A + P + W G + + + ++ + ++F+ L + + Sbjct: 834 TSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYES 893 Query: 881 LRQPTLVLAAVPLAMIGGLAALHLRGMTLNVSSAVGFIALFGVAVLNAVLMLAQINRLRQ 940 P V+ VPL ++G L A L +V VG + G++ NA+L++ L + Sbjct: 894 WSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLME 953 Query: 941 DVGMSLREAVVAGAVSRMRPVLMTATVAALGLAPAMLATGLGSDVQRPLATVVVGGLVTA 1000 G + EA + R+RP+LMT+ LG+ P ++ G GS Q + V+GG+V+A Sbjct: 954 KEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSA 1013 Query: 1001 TLLTLVLLPSLYYL 1014 TLL + +P + + Sbjct: 1014 TLLAIFFVPVFFVV 1027 Score = 88.0 bits (218), Expect = 1e-19 Identities = 66/344 (19%), Positives = 137/344 (39%), Gaps = 15/344 (4%) Query: 682 VADQVAFALHKVPGAADIAVDVEPPLPNLQVRFDREAAARYGINAADVSDLISTG----I 737 VA V L ++ G D+ + +++ D + +Y + DV + + Sbjct: 158 VASNVKDTLSRLNGVGDVQLFGAQYA--MRIWLDADLLNKYKLTPVDVINQLKVQNDQIA 215 Query: 738 GGSPIGQMYLGQKSYDLTVRFPQRYRNDPQAIGALRLRTAA-GAEIPLSAVANIATTS-G 795 G G L + + ++ R++N P+ G + LR + G+ + L VA + Sbjct: 216 AGQLGGTPALPGQQLNASIIAQTRFKN-PEEFGKVTLRVNSDGSVVRLKDVARVELGGEN 274 Query: 796 QSVIVREMGRRNIIVRLNVR-GRDLSSFLSDAQATLARQVHLDPQHMQLVWGGQFENLQR 854 +VI R G+ + + + G + +A LA PQ M++++ + Sbjct: 275 YNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ 334 Query: 855 AQARLLV---VLPTTLCIMFVLLFGAFGNLRQPTLVLAAVPLAMIGGLAALHLRGMTLNV 911 +V L + + LF N+R + AVP+ ++G A L G ++N Sbjct: 335 LSIHEVVKTLFEAIMLVFLVMYLF--LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT 392 Query: 912 SSAVGFIALFGVAVLNAVLMLAQINRLRQDVGMSLREAVVAGAVSRMRPVLMTATVAALG 971 + G + G+ V +A++++ + R+ + + +EA ++ A V + Sbjct: 393 LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 972 LAPAMLATGLGSDVQRPLATVVVGGLVTATLLTLVLLPSLYYLM 1015 P G + R + +V + + L+ L+L P+L + Sbjct: 453 FIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATL 496
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 58.7 bits (142), Expect = 1e-11 Identities = 38/210 (18%), Positives = 75/210 (35%), Gaps = 28/210 (13%) Query: 114 SAELASAYSDAGKARATLEQARLELARQKALAADSISAARDLQAAQQAFDSAQNDARAAS 173 EL S + + + A+ E L + I L+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD--KLRQTTDNIGLLTLELAKNE 322 Query: 174 DRLAQLGVAAQASSHRRYVVRAPIAGRLVDLSA-ALGGFWNDTSASLMTVADISQVWLTA 232 +R + V+RAP++ ++ L GG ++ V + + +TA Sbjct: 323 ERQ------------QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 233 SVPEREIGQVFEGQPVTASLEAYPAQRF---VGQVQHL--DDLLDPAT-------RTLKV 280 V ++IG + GQ +EA+P R+ VG+V+++ D + D +++ Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEE 430 Query: 281 RVALENRDGL-LKPGMFARAQFHSRPRQAL 309 + L GM A+ + R + Sbjct: 431 NCLSTGNKNIPLSSGMAVTAEIKTGMRSVI 460 Score = 37.1 bits (86), Expect = 8e-05 Identities = 24/105 (22%), Positives = 40/105 (38%), Gaps = 5/105 (4%) Query: 76 VLPERLVRVVPPLAGRVVALPKTLGDTVRAGDVLCVLDSAELASAYSDAGKARATLEQAR 135 R + P V + G++VR GDVL L + A +D K +++L QAR Sbjct: 91 THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTA---LGAEADTLKTQSSLLQAR 147 Query: 136 LELARQKAL--AADSISAARDLQAAQQAFDSAQNDARAASDRLAQ 178 LE R + L + + + F + + L + Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 120 bits (303), Expect = 7e-32 Identities = 72/325 (22%), Positives = 117/325 (36%), Gaps = 43/325 (13%) Query: 78 NADLAQQAGARGQGVKLAVLDDNLVPSYAPISGKVDSFNDYTASPGTPESSANALRGHGT 137 A G+GVK+AVLD + + ++ ++T GHGT Sbjct: 30 QAPAVWNQTR-GRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGT 88 Query: 138 IVSALVLGSAQDGFAGGVAPDADLFYARICAENSCGTQQTRRAAVDLAAA-GVRIANLSI 196 V+ + + + GVAP+ADL ++ + G + A V I ++S+ Sbjct: 89 HVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSL 148 Query: 197 GASYPDAAASANAALAWKYALTPLVQADALIVASTGNEGAAEAS-----YPAATPVQEAS 251 G A K A V + L++ + GNEG + YP Sbjct: 149 GGPEDVPELHE----AVKKA----VASQILVMCAAGNEGDGDDRTDELGYPGCYN----- 195 Query: 252 VRNNWLAVGAINIDSAGNAAGLTSYSNHCGAAAQWCLVAPGSYTAPALAGTELQGQIAGT 311 ++VGAIN D + +SN + LVAPG + G + +GT Sbjct: 196 ---EVISVGAINFDR-----HASEFSNSN---NEVDLVAPGEDILSTVPGGKYA-TFSGT 243 Query: 312 SFSTAAVSGVAAQVLGVYPW-----MSASNLQQTLLTTATDLGDPGVDALYGWGLVNAAK 366 S +T V+G A + + ++ L L+ LG + G GL+ Sbjct: 244 SMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLG--NSPKMEGNGLLYLTA 301 Query: 367 AIKGPGQFASNWAANVTAGYDSTFS 391 + + + AG ST S Sbjct: 302 V----EELSRIFDTQRVAGILSTAS 322
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (288), Expect = 5e-33 Identities = 76/263 (28%), Positives = 111/263 (42%), Gaps = 7/263 (2%) Query: 4 GIKQRIALISGGDSGMGKETARQLLEAGVRVAITDLPNGTLDQAVAELSGLGEII-AIEG 62 GI+ +IA I+G G+G+ AR L G +A D L++ V+ L A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 63 DVTQEQDVIHIWTQVRAQLGEPDIYVNAAGVTGATGDFLEVSDAGWLETLDINLMGAVRM 122 DV + I ++ ++G DI VN AGV G +SD W T +N G Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 123 CRQAIPAMRRKQWGRIVLFASEDAVQPYVDELAYCASKAGILSLAKGLSKAYGADNVLVN 182 R M ++ G IV S A P AY +SKA + K L N+ N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 183 TVSPAFIATPMTDKMMQKRAHENGTSVEEAIASFLDEERPGMALKRRGRPEEVASVVAFL 242 VSP T+ MQ + E+ I L+ + G+ LK+ +P ++A V FL Sbjct: 184 IVSPG-----STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 243 CSERASFINGAGVRVDSGSVFTI 265 S +A I + VD G+ + Sbjct: 239 VSGQAGHITMHNLCVDGGATLGV 261
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 31.4 bits (71), Expect = 0.004 Identities = 16/46 (34%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 168 SQSELARRLVADGYPVQQSHISRMAD---AVR---------YLLPA 201 +Q EL L DGY V Q+ +SR V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 27.5 bits (60), Expect = 0.048 Identities = 15/41 (36%), Positives = 21/41 (51%), Gaps = 4/41 (9%) Query: 124 ATPARASRPAKPAPVQASADPLVDTTPFGVDAQPLDTSAAP 164 ++A + P+PV A+A PL+ QPL T AAP Sbjct: 193 EAQSKAEVISTPSPVTAAASPLITPH----QTQPLPTVAAP 229
>PF02370#M protein repeat Length = 168 Score = 30.8 bits (69), Expect = 0.006 Identities = 13/64 (20%), Positives = 25/64 (39%), Gaps = 4/64 (6%) Query: 84 KSQREENQRLRQRENSIDQRINSAL----ETERSNLRRDQQQAASERQQTEGLLADLQQR 139 ++ ENQ LR+RE +I E + RR++ + + + + QQ Sbjct: 51 RALMGENQDLRKREGQYQDKIEELEKERKEKQERPERREKFERQHQDKHYQEQQKKHQQE 110 Query: 140 LDSI 143 + Sbjct: 111 QQQL 114
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 26.0 bits (57), Expect = 0.045 Identities = 8/25 (32%), Positives = 11/25 (44%), Gaps = 3/25 (12%) Query: 20 GWRAYARGERRLSSWLASKGVPVVG 44 GW + + L +G PVVG Sbjct: 62 GWATLDKA---VGGILQQQGWPVVG 83
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 29.4 bits (65), Expect = 0.016 Identities = 22/78 (28%), Positives = 34/78 (43%), Gaps = 7/78 (8%) Query: 250 QQLAQQYSPMID---KYRDDVASIRLGATLGTRSMQ----AMTLADGIDQLRGPLASGAG 302 QQ +Q +ID +YR+++ S R + TL I Q R L Sbjct: 33 QQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRWINYQQFIQTLEKAITQHRQQLNQWTQ 92 Query: 303 RADMAAARWEEVRQRMQS 320 + D+A W E +QR+Q+ Sbjct: 93 KVDIALNSWREKKQRLQA 110
>PF05043#Transcriptional activator Length = 493 Score = 32.6 bits (74), Expect = 0.003 Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 14/86 (16%) Query: 68 IAGLLYLKHAYGLSDEAVCERWLENPYWQFFTGEVVFQTCLPCDPSSLTRWRQRLGEAGM 127 +A ++ L +E VC+ ++ FF E +F C+ D S + + L + Sbjct: 241 VAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESLFMKCVKKD-SYVEKSYHLLSDFID 299 Query: 128 E-------------ELLAHTINTAHV 140 + L+ H NTAH+ Sbjct: 300 QISVKYQIEIENKDNLIWHLHNTAHL 325
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 26.8 bits (59), Expect = 0.038 Identities = 21/111 (18%), Positives = 41/111 (36%), Gaps = 17/111 (15%) Query: 23 ILVLIIFFVVTTTF-----DARSTLQLQLPTASDQHSSTPPRSLSVLVNADGRYFINDQE 77 +LV+ + FV + D Q Q T + ++ V + G+ + Sbjct: 7 LLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAAGSAADQGVPASGQGKLISVKTD 66 Query: 78 VLRSDVDSLKQTIAQIAGDDREQTVLM----RADARTPYQAVVTAQDALGQ 124 VL +++ G D EQ +L ++ P+Q + T+ + Q Sbjct: 67 VLDLTINTR--------GGDVEQALLPAYPKELNSTQPFQLLETSPQFIYQ 109
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.1 bits (68), Expect = 0.011 Identities = 19/77 (24%), Positives = 26/77 (33%), Gaps = 14/77 (18%) Query: 7 LIVGVTGISGYNLANVLLADGWTVYGL-------------ARRP-LPHDGVIPVAADLLD 52 L+ G G G++++ LL G V G+ AR L G DL D Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLAD 63 Query: 53 AESTNNALRGLPITHVF 69 E + VF Sbjct: 64 REGMTDLFASGHFERVF 80
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.0 bits (80), Expect = 5e-04 Identities = 18/67 (26%), Positives = 25/67 (37%), Gaps = 13/67 (19%) Query: 22 GASFEVADGELMVLVGPSGCGKSTLLRMIAGLEDISAGTLKIGERVVNDVAPKDRDIAMV 81 G F+ + +VL G G GKSTL+ + GL+ S IG +D Sbjct: 592 GCKFDYS----VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGT---------GKDSYEQ 638 Query: 82 FQSYALY 88 Y Sbjct: 639 IAGIVAY 645
>PF04183#IucA / IucC family Length = 580 Score = 29.1 bits (65), Expect = 0.027 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 4/45 (8%) Query: 71 ERLQWKREEIDALIVVTQSPDYPIPATAII--LQDRLGLSHATVA 113 ER W IDA + D P+ A ++ L+ L +S ATVA Sbjct: 51 ERGIWGWLWIDAQTLRCA--DEPVLAQTLLMQLKQVLSMSDATVA 93
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 109 bits (274), Expect = 5e-31 Identities = 68/254 (26%), Positives = 115/254 (45%), Gaps = 15/254 (5%) Query: 10 LAGKRILVTGASSGIGRQIAISCAELGAQVAISGRDRARLASTLEALAGEGHVTIAADLD 69 + GK +TGA+ GIG +A + A GA +A + +L + +L E A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 70 R------QEDIDHLVAHVGVLDGMAHAAGISRLVPLRLVNRAHLDDMFSSNTFAPMLLTR 123 E + +G +D + + AG+ R + ++ + FS N+ +R Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 124 GLLAKKRIAAQGSLVFVASVASHIGPMASSAYAASKSALLGMVRSLAQEVAKNGIRANCI 183 + GS+V V S + + + +AYA+SK+A + + L E+A+ IR N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 184 APGYVRTPLLDGL--------QGSGGNMEGLFELTPLG-MGEPEDVAYAVAFLLADASRW 234 +PG T + L Q G++E PL + +P D+A AV FL++ + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 235 ITRNYFVVDGGLTV 248 IT + VDGG T+ Sbjct: 246 ITMHNLCVDGGATL 259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 97.0 bits (241), Expect = 2e-26 Identities = 63/258 (24%), Positives = 113/258 (43%), Gaps = 19/258 (7%) Query: 7 SAFSLNGKTILVTGASSGLGRQIAIACAQRGARIVLAGRDKDRLAQTQAQLQGTGHVSV- 65 +A + GK +TGA+ G+G +A A +GA I + ++L + + L+ + Sbjct: 2 NAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 66 ----LGDLTGTADREALAAAAGATLHGLVHCAGMQKHCPIRQLTEAAMTEMYTVNFLAPV 121 + D + A + LV+ AG+ + I L++ ++VN Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 122 MLTQRLLHANAIASQGSIVFMLSTAAHLGTRGVGPYSAMKAGLIGIIKCLALEQAKRRIR 181 ++ + GSIV + S A + + Y++ KA + KCL LE A+ IR Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 182 VNGISPSAVATPM----WGADQLDAQKARH---------PLG-LGEPQDVANAAIYLLAD 227 N +SP + T M W + Q + PL L +P D+A+A ++L++ Sbjct: 182 CNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSG 241 Query: 228 ASRWVTGTSLVMDGGSIL 245 + +T +L +DGG+ L Sbjct: 242 QAGHITMHNLCVDGGATL 259
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 61.2 bits (148), Expect = 8e-16 Identities = 27/84 (32%), Positives = 47/84 (55%) Query: 22 AGTQGTPATQAPSFSETLRGAIGGVNEAQQKAGALSKAFEMGDPNADLARVMVASQQSQV 81 A Q + SF+ L A+ +++ Q A ++ F +G+P L VM Q++ V Sbjct: 20 ARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASV 79 Query: 82 AFRATVEVRNRLVQAYQDVMNMPL 105 + + ++VRN+LV AYQ+VM+M + Sbjct: 80 SMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 352 bits (905), Expect = e-117 Identities = 187/575 (32%), Positives = 300/575 (52%), Gaps = 45/575 (7%) Query: 16 KAGQWFDRVRSLQITRKLTMMAMIALAVAAGLAVFFWSQKPGYQSLYTGLDEKGNAEAAD 75 K +W +R+R+ ++ ++ + AVA +A+ W++ P Y++L++ L ++ Sbjct: 11 KPLEWLNRLRANP---RIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVA 67 Query: 76 LLRTAQIPYKIDQGTGAISVPQDRLYDARLKLAGSGLTGKETGGGFELMEKDPGFGVSQF 135 L IPY+ G+GAI VP D++++ RL+LA GL K GFEL++++ FG+SQF Sbjct: 68 QLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLP-KGGAVGFELLDQEK-FGISQF 125 Query: 136 VENARYQHALETELSRTIGTLRPVREARVHLAIPKPSAFTRQRDVASASVVLELRGGQGL 195 E YQ ALE EL+RTI TL PV+ ARVHLA+PKPS F R++ SASV + L G+ L Sbjct: 126 SEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRAL 185 Query: 196 ERNQVDAIVNLVASSIPDMTPERVTVVDQSGRMLSIADPNSDAAQHAAQFEQVRRQESSY 255 + Q+ A+V+LV+S++ + P VT+VDQSG +L+ ++ + AQ + ES Sbjct: 186 DEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLN-DAQLKFANDVESRI 244 Query: 256 NQRIRELLEPMTGPGRVNPETSVDMDFSVVEEARELYN----GEPAKLRSEQVSD-TSTS 310 +RI +L P+ G G V+ + + +DF+ E+ E Y+ A LRS Q++ Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 311 ATGPQGPPGATSNSPGQPPAPAVAGAPGT--------PAAANGQAAAPATPTESSKSATR 362 A P G PGA SN P PP A P T P + + A P + ++ T Sbjct: 305 AGYPGGVPGALSNQP-APPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETS 363 Query: 363 NYELDRTLQHTRQPAGRIKRVSVAVLLDNVPRPGAKGKMVEQPLTAAELTRIEGLVKQAV 422 NYE+DRT++HT+ G I+R+SVAV+++ K PLTA ++ +IE L ++A+ Sbjct: 364 NYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKP----LPLTADQMKQIEDLTREAM 419 Query: 423 GFDAARGDTVSVMNAPFVREAVAGEEGPKWWEDPRVQNGLRLLVGAVVVLALLF----GV 478 GF RGDT++V+N+PF G E P W + + L ++VL + + Sbjct: 420 GFSDKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAG-RWLLVLVVAWILWRKA 478 Query: 479 VRPTLRQLTGVTAVKDKQGKAGKDGTPQSADVRMVDDDDDLMPRLEEDTAQIGQDKKTPI 538 VRP L + +Q + ++ + A + D+ L Q ++ Sbjct: 479 VRPQLTRRVEEAKAAQEQAQVRQET--EEAVEVRLSKDEQL------------QQRRANQ 524 Query: 539 ALPDAYEERMRLAREAVKADSKRVAQVVKGWVASE 573 L E + RE D + VA V++ W++++ Sbjct: 525 RLG--AEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 307 bits (788), Expect = e-106 Identities = 106/329 (32%), Positives = 199/329 (60%) Query: 1 MTGVQRAAVLLLSLGESDAAEVLKHMDPKEVQKIGIAMATMTGISRDQVEKVMDEFNGEL 60 +TG Q+AA+LL+S+G +++V K++ +E++ + +A + I+ + + V+ EF + Sbjct: 15 LTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELM 74 Query: 61 AGKTSLGVGADDYIRNVLIQALGADKAGGLIDRILLGRNTTGLDTLKWMDPRAVADLVRN 120 + + G DY R +L ++LG KA +I+ + + + ++ DP + + ++ Sbjct: 75 MAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQ 134 Query: 121 EHPQIIAIVMAHLDSDQAAEALKLLPERTRADVLLRIATLDGIPPNALSELNDIMERQFA 180 EHPQ IA+++++LD +A+ L LP + +V RIA +D P + E+ ++E++ A Sbjct: 135 EHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKLA 194 Query: 181 GNQNLKSSNVGGIKVAANILNFLDTGADQGVLGEIGKIDADLAGKIQDLMFVFDNLVDLD 240 + ++ GG+ I+N D ++ ++ + + D +LA +I+ MFVF+++V LD Sbjct: 195 SLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLLD 254 Query: 241 DRGLQTLLREVSGERLGLALRGADVKVREKITRNMSQRAAEILLEDMEARGPVRLADVEA 300 DR +Q +LRE+ G+ L AL+ D+ V+EKI +NMS+RAA +L EDME GP R DVE Sbjct: 255 DRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVEE 314 Query: 301 AQKEILTIVRRLADEGAISLGGAGAEAMV 329 +Q++I++++R+L ++G I + G E ++ Sbjct: 315 SQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 42.5 bits (99), Expect = 3e-07 Identities = 36/159 (22%), Positives = 76/159 (47%), Gaps = 7/159 (4%) Query: 51 HEGFARGHAEGFAQGQSEVRRLTAQIDGILDNFTRPLARLENEVVGALGELAVRIAGQLV 110 EG A+G +G A+ +S+ + A++ ++ F L L++ + L ++A+ A Q++ Sbjct: 73 QEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVI 132 Query: 111 GRAYQADPQLLADLVGEAVDAVGGAGREVEVRLHPDDITALLPHLAPSSTT---RVAPDM 167 G+ D L + + + + ++R+HPDD+ + L + + R+ D Sbjct: 133 GQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDP 192 Query: 168 SLSRGDLRVHAESVRIDGTLDARLRAALETVMRKSGAGL 206 +L G +V A+ +G LDA + + + R + G+ Sbjct: 193 TLHPGGCKVSAD----EGDLDASVATRWQELCRLAAPGV 227
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 26.7 bits (58), Expect = 0.026 Identities = 34/140 (24%), Positives = 58/140 (41%), Gaps = 4/140 (2%) Query: 1 MMQSKRIDPLLRRAQEQEDKVARDLAERQRVLETHQSRLEELRRYAEEYANSQMAGTSAV 60 M + + L A+++ + AR L E +R + + +L+ L Y EY N+ + SA Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ALSNR----RAFLDRLDSAVLQQAQTVQSNIAKVEAERTRLLLASREKQVLEQLAASYRA 116 SNR + F+ L+ A+ Q Q + KV+ + Q + L Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 117 QENKVIERRDQREMDDLGAR 136 R DQ++MD+ R Sbjct: 121 AALLAENRLDQKKMDEFAQR 140
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 51.8 bits (123), Expect = 3e-09 Identities = 69/325 (21%), Positives = 118/325 (36%), Gaps = 7/325 (2%) Query: 97 DAKQAKPSTAKDAATTDKSTAATATKTGKPAKATATSEDPPAETATATDAGWPPAGLGGF 156 +A + +T K A +T TK G+P + S+ A D P Sbjct: 35 EALAGETTTDKAAPQLLVATDKPTTK-GEPLISDIVSDAQQANLLIPVDETPPVINDEQS 93 Query: 157 GMGLLAQALPGGDVLAAAAAALTASMAGANGATATATALPTDATAAATANAGTALPALGA 216 L A A A TA+ A N A Sbjct: 94 TSTPLTTAQTMALAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPST 153 Query: 217 LVPTAVAGAKPTSTTAVSGDAQTAALMSMAAKALEPAADDSAAPATPDAPAFVLPTTTAP 276 ++PT T+ AQ A+ L P ++ + A + + +P Sbjct: 154 VLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASP 213 Query: 277 ALTRLQEAAPIFSASPTPTPDLGSDNFDDAIGARMSWLADQKIGHAHIKVTPNEMGPVEV 336 +T Q A+P + LGS + ++ +S Q A +++ P ++G V++ Sbjct: 214 LITPHQTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQI 273 Query: 337 RLHLEGDKVNASFTAANADTRQALEQSLPRLREMLGQNGFQLGQADV------GQQQQNS 390 L ++ ++ + + R ALE +LP LR L ++G QLGQ+++ GQQQ S Sbjct: 274 SLKVDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAAS 333 Query: 391 AGNRNGGNDNGNGLTLDDAPPVGIP 415 ++ N L +D + +P Sbjct: 334 QQQQSQRTANHEPLAGEDDDTLPVP 358
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 259 bits (662), Expect = 9e-87 Identities = 91/327 (27%), Positives = 163/327 (49%), Gaps = 14/327 (4%) Query: 3 VSDLLSQDEIDALLHGVDSGAVNTEPEPLPGEARQ-----YDLSSQDRIIRGRMPTLEMV 57 ++++LSQDEID LL + SG + E + YD D+ + +M TL ++ Sbjct: 1 MTEVLSQDEIDQLLTAISSG--DASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLM 58 Query: 58 NERFARLWRIGLFNLIRRSADLSVRGIDLVKFNEYMHSLYVPTNLNLIRFKPLRGTGLIV 117 +E FARL L +R + V +D + + E++ S+ P+ L +I PL+G ++ Sbjct: 59 HETFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLE 118 Query: 118 FEPTLVFTVVDNFFGGDGRFHTRIEGREFTATEMRVIQLMLKQTFADLKEAWAPVMDVDF 177 +P++ F+++D FGG G+ R+ T E V++ ++ + A+++E+W V+D+ Sbjct: 119 VDPSITFSIIDRLFGGTGQAAKVQ--RDLTDIENSVMEGVIVRILANVRESWTQVIDLRP 176 Query: 178 EYINSEINPHFANIVTPREYVVVCRFHVELEGGGGEIHITLPYSMLEPIRELLDAG--IQ 235 E NP FA IV P E VV+ ++ G ++ +PY +EPI L + Sbjct: 177 RLGQIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFS 236 Query: 236 SDRNDRDDSWNVMLREQLDTAEVTLSSVLASKRMSLRQLTGLKVGDIL---PIDLPAQVP 292 S R + +LR++L T ++ + + + S R+S+R + GL+VGDI+ + Sbjct: 237 SVRRSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFV 296 Query: 293 LCVEDIPLFTGEFGVSNGNNAVKITAV 319 L + + F + GV A +I Sbjct: 297 LSIGNRKKFLCQPGVVGKKIAAQILER 323
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 113 bits (285), Expect = 5e-36 Identities = 50/90 (55%), Positives = 74/90 (82%) Query: 22 DQNAADLNLDVILDVPVTLSLEVGRARIPIRNLLQLNQGSVVELERGAGEPLDVYVNGTL 81 D + A ++D+I+D+PV L++E+GR R+ I+ LL+L QGSVV L+ AGEPLD+ +NG L Sbjct: 46 DVSGAMQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYL 105 Query: 82 IAHGEVVVINDRFGIRLTDVVSPSERIRRL 111 IA GEVVV+ D++G+R+TD+++PSER+RRL Sbjct: 106 IAQGEVVVVADKYGVRITDIITPSERMRRL 135
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 60.8 bits (147), Expect = 3e-12 Identities = 24/48 (50%), Positives = 30/48 (62%) Query: 91 SSNDLLLGGGGNDTLIGGQGNDVLIGGPGHDVLRGGAGNDIYIVNDGD 138 S ND+L+G ++ L GG GNDVL GG G D L GGAG D ++ G Sbjct: 347 SGNDILVGNSADNILQGGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQ 394 Score = 57.7 bits (139), Expect = 3e-11 Identities = 18/48 (37%), Positives = 26/48 (54%) Query: 91 SSNDLLLGGGGNDTLIGGQGNDVLIGGPGHDVLRGGAGNDIYIVNDGD 138 N + G + IGG GND+L+G ++L+GGAGND+ G Sbjct: 329 KGNVSIAHGVTIENAIGGSGNDILVGNSADNILQGGAGNDVLYGGAGA 376 Score = 32.2 bits (73), Expect = 0.004 Identities = 7/40 (17%), Positives = 9/40 (22%) Query: 100 GGNDTLIGGQGNDVLIGGPGHDVLRGGAGNDIYIVNDGDV 139 G N T G D + I + D Sbjct: 259 GANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDA 298
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.3 bits (78), Expect = 3e-04 Identities = 19/157 (12%), Positives = 43/157 (27%), Gaps = 5/157 (3%) Query: 44 ANQAGQTLERQRSQGDAEPNRVRAARPAESAIQPPQESGARGSQSQRNEAPLAVAQGGPP 103 + + + + + Q AEP R P + +P ++ Q + + Sbjct: 1127 SQVSPKQEQSETVQPQAEPAREND--PTVNIKEPQSQTNTTADTEQPAKE---TSSNVEQ 1181 Query: 104 TAASDSPACRAAQKELEFVTSIRTIGQDEKRMRANAAIAHVNASCGTNTPLMQEPPTVVA 163 + + Q ++ + + + P EP T + Sbjct: 1182 PVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSS 1241 Query: 164 PQAVTITHCDTGFCYDTAGALYKRSGPSSIIGPTGRS 200 T+ CD A R+ + G++ Sbjct: 1242 NDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKA 1278
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 28.2 bits (62), Expect = 0.027 Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 4/77 (5%) Query: 36 APVALASLRPVVSKGARAMLGVAFAELDAVACVALVPEFLQRHEGLIGTQSQLF-DGVEQ 94 A VA+ + VV KGA A LG A +++ LVP L++ L S+LF G+++ Sbjct: 418 AMVAVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQ---LAQNGSKLFTQGMQR 474 Query: 95 MLMRLEDAGCVWGIVTN 111 + L + G G+ TN Sbjct: 475 ITSGLGNVGSKMGLQTN 491
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 27.7 bits (61), Expect = 0.038 Identities = 21/100 (21%), Positives = 38/100 (38%), Gaps = 12/100 (12%) Query: 56 GARVLDVGCGGGL---LSESMARLGAQVTAIDLAPE-LVKVARLHSLESGVQVDYRVQSV 111 G G G+ ++ ++A GA + A+D PE L KV E+ + Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 112 EDLAAEQAGSFDAVTCMEMLEHVPDPTAIIRACASLLKPG 151 + A ++ + + P I+ A +L+PG Sbjct: 68 DSAAIDE-------ITARIEREM-GPIDILVNVAGVLRPG 99
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 35.1 bits (81), Expect = 5e-04 Identities = 16/26 (61%), Positives = 19/26 (73%) Query: 356 TLGGARALGLGDTIGSIEVGKQADLV 381 T+ A A GL IGS+EVGK+ADLV Sbjct: 410 TINPAIAHGLSHEIGSLEVGKRADLV 435
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 27.1 bits (60), Expect = 0.022 Identities = 11/37 (29%), Positives = 18/37 (48%) Query: 12 AQAKAKLLDELQKLEEQEKTERASEASSAHATIVSLL 48 Q + LLD L ++ + + R S+ H I+S L Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFL 391
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 280 bits (717), Expect = 2e-95 Identities = 96/320 (30%), Positives = 160/320 (50%), Gaps = 10/320 (3%) Query: 4 FPLHLIPNDTKIDFMSWRKPVLILMLVLAVASVGIIVRKGFNYALEFTGGTLVQASFQKT 63 F L L+P T DF W+ +V+ +ASV + + G N+ ++F GGT ++ Sbjct: 3 FRLKLVPEKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTA 62 Query: 64 VDVDQVREKLSRVGFENAQVQNAR------GGNEVMIRLQPHGQNNNRDDAAR---TVAE 114 +DV R L + + + R + MIR+Q + + Sbjct: 63 IDVGVYRAALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVN 122 Query: 115 DVRKAVSSDENPATVQPGEFVGPQVGKDLALNGVYATVFMLVGFLIYIAFRFEWKFAVVA 174 V A+++ + + E VGP+V +L V++ + V + YI RFEW+FA+ A Sbjct: 123 KVETALTAVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGA 182 Query: 175 SLTALFDLLVTVAFVSLTGREFDLTVLAGLLSVMGFAINDIIVVFDRVRENFRALRVEPL 234 + + D+L+TV ++ +FDLT +A LL++ G++IND +VVFDR+REN + PL Sbjct: 183 VVALVHDVLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPL 242 Query: 235 -EVLNRSINQTLSRTVITAVMFFLSALALYIYGGESMEGLAETHMIGAVIVVISSVIVAV 293 +V+N S+N+TLSRTV+T + L+ + + I+GG+ + G + G SSV VA Sbjct: 243 RDVMNLSVNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAK 302 Query: 294 PMLSIGPFAVTKQDLLPKAK 313 ++ K+ P K Sbjct: 303 NIVLFIGLDRNKEKKDPSDK 322
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 88.0 bits (218), Expect = 4e-21 Identities = 36/175 (20%), Positives = 83/175 (47%), Gaps = 3/175 (1%) Query: 447 VIGPSLGAENVERGVTAVVYSFLFTLVFFTIYYRVFGAITSV-ALLFNLLIVVAVMSLFG 505 +GP + E V V +++ + + + + + + A+ +V AL+ ++L+ V + ++ Sbjct: 142 SVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVLQ 201 Query: 506 ATMTLPGFAGLALSVGLSVDANVLINERIREELRL--GVPAKSAIAAGYEKAGGTILDAN 563 L A L G S++ V++ +R+RE L +P + + + + Sbjct: 202 LKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTG 261 Query: 564 LTGLIVAVALYAFGTGPLKGFALTMMIGIFASMFTAITVSRALAVLIYGSRKKLK 618 +T L+ V + +G ++GF M+ G+F ++++ V++ + + I R K K Sbjct: 262 MTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGLDRNKEK 316
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 26.7 bits (59), Expect = 0.036 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 19 EDARASTAQIARRLGLSRTTVQSRIEKL 46 R + + A LGL+R T++ +I +L Sbjct: 446 TATRGNQIKAADLLGLNRNTLRKKIREL 473
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 49.8 bits (119), Expect = 1e-08 Identities = 39/204 (19%), Positives = 59/204 (28%), Gaps = 53/204 (25%) Query: 269 IAPGAKLVMY-----FAPNTDNGFLEAINAAIHDAEHSPGIIAISWGFTESQWTPQSRQA 323 +AP A L++ + ++ I AI II++S G E Sbjct: 106 VAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD---IISMSLGGPEDVPELHE--- 159 Query: 324 YDCAFRAAALMGITVCIAAGDDGASDGQPGLNVCFPASSPFVLACGGTRLQVTADSANEQ 383 A + A I V AAG++G D + + +P V++ G + Sbjct: 160 ---AVKKAVASQILVMCAAGNEGDGDDRTD-ELGYPGCYNEVISVGAI------NFDRHA 209 Query: 384 AWASGGGGESRFFARPAWQNNLRLTDAQHQSRQLRMRGVPDVAANADAQTGYYLSINGQP 443 + S E A P + G Y + Sbjct: 210 SEFSNSNNEVDLVA-------------------------PGEDILSTVPGGKYAT----- 239 Query: 444 AVMGGTSAAAPLWAALLARIYGAN 467 GTS A P A LA I Sbjct: 240 --FSGTSMATPHVAGALALIKQLA 261
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 112 bits (282), Expect = 2e-26 Identities = 81/297 (27%), Positives = 109/297 (36%), Gaps = 40/297 (13%) Query: 1040 GAGADTIYAGAGDDVVNAGAGDDTVFAGTGNDMVAGYDGDDFIDGGAGDDWLDGDYDV-- 1097 G G D ++ AG + AG G D V+ + DG + G+Y V Sbjct: 617 GDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATE--------AGNYTVTR 668 Query: 1098 -VPAAGQQAVETLTIHGAQMVVRNVLEASRHGNDVLDGGAGNDRMRGGGRDDILYGGTGN 1156 + + E + + R R G + L G T Sbjct: 669 VLGGDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRA 728 Query: 1157 DEIFGDQDRMNGPETGDDFLDGGEGDDTLVGGGGADVLLGGAGADILEGDDAADQVDAKW 1216 D+ FG + D G +GDD + G G D L G G D L G + Sbjct: 729 DKFFGSK--------FTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGN--------- 771 Query: 1217 HGADRLDGGAGNDSMYGGGGDDVLAGGEGDDWLAGEDEHAVDAVSTLTGNDTLDGGVGND 1276 G D+L GG GND + G G++ L GG+GDD + + L GG GND Sbjct: 772 -GDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNS--------LAKNVLFGGKGND 822 Query: 1277 TLVGGNGNDALMGGEGRDTLYGGAGHDTLIGGAGAD---LLDGGLGNDTYVIDAADL 1330 L G G D L GGEG D L GG G+D +G + D G D + D Sbjct: 823 KLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDF 879 Score = 112 bits (281), Expect = 2e-26 Identities = 76/307 (24%), Positives = 110/307 (35%), Gaps = 67/307 (21%) Query: 1054 VVNAGAGDDTVFAGTGNDMVAGYDGDDFIDGGAGDDWL---DG----------------- 1093 + G GDD VF G+ + G D + D DG Sbjct: 613 ESHLGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGG 672 Query: 1094 --------------------------DYDVVPAAGQQAVETLTIHGAQMVVRNVLEASRH 1127 Y+ G+ ET ++ + ++ Sbjct: 673 DVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFF 732 Query: 1128 G---NDVLDGGAGNDRMRGGGRDDILYGGTGNDEIFGDQDRMNGPETGDDFLDGGEGDDT 1184 G D+ G G+D + G +D LYG GND + G GDD L GG+G+D Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGN--------GDDQLYGGDGNDK 784 Query: 1185 LVGGGGADVLLGGAGADILEGDDAADQVDAKWHGADRLDGGAGNDSMYGGGGDDVLAGGE 1244 L+G G + L GG G D + + + L GG GND +YG G D+L GGE Sbjct: 785 LIGVAGNNYLNGGDGDDEFQVQGNS-------LAKNVLFGGKGNDKLYGSEGADLLDGGE 837 Query: 1245 GDDWLAGEDEHAVDAVSTLTGNDTL-DGGVGNDTLVGGNGN--DALMGGEGRDTLYGGAG 1301 GDD L G + + + G+ + D G D L + + D EG D + Sbjct: 838 GDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLADIDFRDVAFKREGNDLIMYKGE 897 Query: 1302 HDTLIGG 1308 + L G Sbjct: 898 GNVLSIG 904 Score = 98.1 bits (244), Expect = 4e-22 Identities = 62/229 (27%), Positives = 96/229 (41%), Gaps = 28/229 (12%) Query: 3145 GTSRNDTLTGTTGNDTIDGLAGADTMTGLAGDDTYIVDNTGDKAVEAANAGTDTVMSSVS 3204 G+ D G G+D I+G G D + G G+DT N D+ G D + Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLY--GGDGNDKL----- 785 Query: 3205 FTLGANVENLVLAGSGA---INGTGNELNNRLTGNAGANVLTGGAGADYLDGGAGTDTLA 3261 +G N + G G + N L G G + L G GAD LDGG G D L Sbjct: 786 --IGVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLK 843 Query: 3262 GGLGNDTYWLARGYGTDTVQENDTTSGNLDIAKFANDVSSRQLWFRKSGNNL-------E 3314 GG GND Y GYG + ++ L +A D+ R + F++ GN+L Sbjct: 844 GGYGNDIYRYLSGYGHHIIDDDGGKEDKLSLA----DIDFRDVAFKREGNDLIMYKGEGN 899 Query: 3315 VSIIGTSDKLVMSNWYA-----GSQYQVERFQAGDGKALQANQVQSLVQ 3358 V IG + + NW+ S +++E+ G+ + + ++ ++ Sbjct: 900 VLSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRIITPDSLKKALE 948 Score = 88.1 bits (218), Expect = 5e-19 Identities = 53/144 (36%), Positives = 62/144 (43%), Gaps = 19/144 (13%) Query: 1930 GDVFNRANSGTPGDDALRGTPGDDELRGLAGNDTIDGLAGNDMLDGGAGADTLRGGDGND 1989 G F G GDD + G G+D L G GNDT+ G G+D L GG G D L G GN+ Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNN 792 Query: 1990 VLIAGEG-----------------GAAGSDTLYGDAGDDILVASLTGPSQLSGGAGGDTF 2032 L G+G G G+D LYG G D+L G L GG G D + Sbjct: 793 YLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGG-EGDDLLKGGYGNDIY 851 Query: 2033 RIGPSGGLHTIVRDDAEARDVLEF 2056 R G H I DD D L Sbjct: 852 RYLSGYGHHIID-DDGGKEDKLSL 874 Score = 78.1 bits (192), Expect = 4e-16 Identities = 48/186 (25%), Positives = 83/186 (44%), Gaps = 31/186 (16%) Query: 2661 HLIGNAGNNTVSGSFQDDIVEGGDGDDVVEDQYAAIRPAAALWSAGQDRDELKGGAGNDR 2720 L G GN+ + G ++ + GGDGDD + Q ++ L GG GND+ Sbjct: 775 QLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQ-----------GNSLAKNVLFGGKGNDK 823 Query: 2721 LVSYAGLDTMDGGAGNDVLVGG---DIYLFGRGDGRDVIESWTGRVSGERSQTLRFKSGV 2777 L G D +DGG G+D+L GG DIY + G G +I+ G + L + + Sbjct: 824 LYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDD-----DGGKEDKLSL-ADI 877 Query: 2778 TAQDVVLRRDGDSLEVSLR-------GSQDAVTVKSFYQDAAASG----VRRIEFADGTA 2826 +DV +R+G+ L + G ++ +T +++++ + + +I G Sbjct: 878 DFRDVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWFEKESGDISNHEIEQIFDKSGRI 937 Query: 2827 WERDTL 2832 D+L Sbjct: 938 ITPDSL 943 Score = 78.1 bits (192), Expect = 5e-16 Identities = 49/151 (32%), Positives = 68/151 (45%), Gaps = 26/151 (17%) Query: 1217 HGADRLDGGAGNDSMYGGGGDDVLAGGEGDDWLAGEDEHAVDAVSTLTGNDTLDGGVGND 1276 + + L G D +G D+ G +GDD ++G GND Sbjct: 717 YSVEELIGTTRADKFFGSKFTDIFHGADGDD--------------------LIEGNDGND 756 Query: 1277 TLVGGNGNDALMGGEGRDTLYGGAGHDTLIGGAGADLLDGGLGNDTYVIDAADLPEGSSD 1336 L G GND L GG G D LYGG G+D LIG AG + L+GG G+D + + +G+S Sbjct: 757 RLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQV------QGNSL 810 Query: 1337 AAELLRDAGGDDTVMLSGAVSSSRTDKGQDL 1367 A +L G+D + S +G DL Sbjct: 811 AKNVLFGGKGNDKLYGSEGADLLDGGEGDDL 841 Score = 75.0 bits (184), Expect = 4e-15 Identities = 68/304 (22%), Positives = 113/304 (37%), Gaps = 57/304 (18%) Query: 896 GGGGDDVLYGGAGDDTLVGGGGADIILADGNGEALVVGNAADAHGTGANDPATGQPRLLM 955 G GDD ++ AG + G G D++ D + + A G T L Sbjct: 616 LGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGN---YTVTRVLGG 672 Query: 956 ASMALAQIGTTPYDSLGQRIRKTDLRTFGVNPLSEVDASGLLAMRAQDIRPLEGDTTQYV 1015 L ++ S+G+R KT R++ E + D + + + Sbjct: 673 DVKVLQEVVKEQEVSVGKRTEKTQYRSY------EFTHINGKNLTETD----NLYSVEEL 722 Query: 1016 AGSQ--ETFAQLNGSEAFMSNVGK---AAGAGADTIYAGAGDDVVNAGAGDDTVFAGTGN 1070 G+ + F ++ F G G D +Y G+D ++ G GDD ++ G GN Sbjct: 723 IGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGN 782 Query: 1071 DMVAGYDGDDFIDGGAGDDWLDGDYDVVPAAGQQAVETLTIHGAQMVVRNVLEASRHGND 1130 D + G G+++++GG GDD ++ + + Sbjct: 783 DKLIGVAGNNYLNGGDGDDEFQ-----------------------------VQGNSLAKN 813 Query: 1131 VLDGGAGNDRMRGGGRDDILYGGTGNDEIFGDQDRMNGPETGDDF--LDGGEGDDTLVGG 1188 VL GG GND++ G D+L GG G+D + G G+D G G + Sbjct: 814 VLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGY--------GNDIYRYLSGYGHHIIDDD 865 Query: 1189 GGAD 1192 GG + Sbjct: 866 GGKE 869 Score = 71.9 bits (176), Expect = 4e-14 Identities = 56/216 (25%), Positives = 88/216 (40%), Gaps = 25/216 (11%) Query: 1617 GNDTIDAGAGNDTVDSGQGRDTFFYSRGD----GVDRYSAGMAAP------ADGDVIRFK 1666 G+D + AG+ + +G+G D +Y + D +D A A GDV + Sbjct: 619 GDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQ 678 Query: 1667 EGLAQSDLMFSRVEDDLLVRVIGTQDRLTVKAAFTSQPLSRIEFGDGRAVAFADLALTPG 1726 E + + ++ + + R + K + L +E G AD Sbjct: 679 EVVKEQEVSVGKRTEKTQYRSYEFT-HINGKNLTETDNLYSVEELIGTT--RADKFFGSK 735 Query: 1727 QAQATAGNDSEIHLLPTGDTVDALAGSDTVYGGVGNDTIDGGEGADMLYGGAGDDALTDA 1786 G D + D ++ G+D +YG GNDT+ GG G D LYGG G+D L Sbjct: 736 FTDIFHGADGD-------DLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGV 788 Query: 1787 RGDNTFDAGDGNDRITGMGTSV-----DAGAGDDVV 1817 G+N + GDG+D G S+ G G+D + Sbjct: 789 AGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKL 824 Score = 69.6 bits (170), Expect = 2e-13 Identities = 38/94 (40%), Positives = 45/94 (47%), Gaps = 4/94 (4%) Query: 2127 LVGGAGHDRLTGFD--FSDDRLVGGAGDDVLSGRGGNDVLSGGAGFDTLAGGAGDDAYLV 2184 L GG G D + + L GG G+D L G G D+L GG G D L GG G+D Y Sbjct: 794 LNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRY 853 Query: 2185 GRGDGRDVITEAGG-SDTLRFGADIAAADVRLVR 2217 G G +I + GG D L ADI DV R Sbjct: 854 LSGYGHHIIDDDGGKEDKLSL-ADIDFRDVAFKR 886 Score = 61.9 bits (150), Expect = 4e-11 Identities = 27/57 (47%), Positives = 37/57 (64%) Query: 1583 DLITGRDGADRIYAGAGDDVVTAGAGDDQIWGDLGNDTIDAGAGNDTVDSGQGRDTF 1639 DLI G DG DR+Y G+D ++ G GDDQ++G GND + AGN+ ++ G G D F Sbjct: 747 DLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEF 803 Score = 59.2 bits (143), Expect = 3e-10 Identities = 37/88 (42%), Positives = 44/88 (50%), Gaps = 11/88 (12%) Query: 2129 GGAGHDRLTGFDFSDDRLVGGAGDDVLSGRGGNDVLSGGAGFDTLAGGAGDDAYLVGR-- 2186 G G+DRL G D +D L GG GDD L G GND L G AG + L GG GDD + V Sbjct: 751 GNDGNDRLYG-DKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNS 809 Query: 2187 --------GDGRDVITEAGGSDTLRFGA 2206 G G D + + G+D L G Sbjct: 810 LAKNVLFGGKGNDKLYGSEGADLLDGGE 837 Score = 58.8 bits (142), Expect = 3e-10 Identities = 78/359 (21%), Positives = 136/359 (37%), Gaps = 75/359 (20%) Query: 1394 VVNGVQVSTARWIRANVTE----DKNLTAEAGGKAYGGRGADRLSLGAGGGMLQGAAGND 1449 V GVQ A + +N+ + N E +++ G G D++ L AG + G+D Sbjct: 580 TVKGVQDKGAVYDYSNLIQHASVGNNQYREIRIESHLGDGDDKVFLSAGSANIYAGKGHD 639 Query: 1450 IFDIAQARDSGGAVL--TFERGDGLDTVTGAVSAQTQAARAANVFEFGEGIAADGVALVR 1507 + + D+G + T G TVT + + + E + V++ + Sbjct: 640 VVYYDKT-DTGYLTIDGTKATEAGNYTVTRVLGGDVKVLQ--------EVVKEQEVSVGK 690 Query: 1508 KFDG-QGMALYLRYGDGDDMVRLDGL-------SGSDDRPFDLARFADGSELAWTDLVAR 1559 + + Q + + +G ++ D L + F ++F D A D Sbjct: 691 RTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGD---- 746 Query: 1560 GIVLDMRERTDGNAGRGDGTPYRDLITGRDGADRIYAGAGDD------------------ 1601 D+ E DGN R G D ++G +G D++Y G G+D Sbjct: 747 ----DLIEGNDGN-DRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDD 801 Query: 1602 ------------VVTAGAGDDQIWGDLGNDTIDAGAGNDTVDSGQGRDTFFYSRGDGVDR 1649 V+ G G+D+++G G D +D G G+D + G G D + Y G G Sbjct: 802 EFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHI 861 Query: 1650 -YSAGMAAPADGDVIRFKEGLAQSDLMFSRVEDDLL-------VRVIGTQDRLTVKAAF 1700 G D + + + D+ F R +DL+ V IG ++ +T + F Sbjct: 862 IDDDG----GKEDKLSLAD-IDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGITFRNWF 915 Score = 57.7 bits (139), Expect = 9e-10 Identities = 35/87 (40%), Positives = 42/87 (48%), Gaps = 6/87 (6%) Query: 2124 RQALVGGAGHDRLTGFDFSDDRLVGGAGDDVLSGRGGNDVLSGGAGFDTLAGGAGDDAYL 2183 G G D + G D +DRL G G+D LSG G+D L GG G D L G AG++ YL Sbjct: 737 TDIFHGADGDDLIEGND-GNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNN-YL 794 Query: 2184 VGRGDGRDVITEAGG---SDTLRFGAD 2207 G GDG D G + L G Sbjct: 795 NG-GDGDDEFQVQGNSLAKNVLFGGKG 820 Score = 56.9 bits (137), Expect = 2e-09 Identities = 37/95 (38%), Positives = 45/95 (47%), Gaps = 6/95 (6%) Query: 828 GGAGADMLEGGTAAASSRQWLYGEAGDDVLTVGAPVDLSAAIAAGETQAGSGNGFAS--L 885 G G D L GG + LYG G+D L A + + GN A L Sbjct: 760 GDKGNDTLSGG----NGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLAKNVL 815 Query: 886 SGGRGDDRLLGGGGDDVLYGGAGDDTLVGGGGADI 920 GG+G+D+L G G D+L GG GDD L GG G DI Sbjct: 816 FGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDI 850 Score = 56.1 bits (135), Expect = 2e-09 Identities = 37/135 (27%), Positives = 53/135 (39%), Gaps = 7/135 (5%) Query: 492 DDKRDLALGADGADVLNTGAGQDFIFAGRGNDILAGGDGNDTLLGGLGSDTYQFTGGFGR 551 +D D G G D L+ G G D ++ G GND L G GN+ L GG G D +Q G Sbjct: 752 NDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSLA 811 Query: 552 DYVLDQDGLGAIQIDGKTLGDAKSAGKADVWVADLDGQRVGLAVYNDAASTTGKKLVITR 611 VL G G ++ G D G+ D + G + + I Sbjct: 812 KNVLFG-GKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHI------IDD 864 Query: 612 AGNVADTITIDNFDL 626 G D +++ + D Sbjct: 865 DGGKEDKLSLADIDF 879 Score = 55.7 bits (134), Expect = 3e-09 Identities = 32/98 (32%), Positives = 45/98 (45%), Gaps = 6/98 (6%) Query: 1953 DELRGLAGNDTIDGLAGNDMLDGGAGADTLRGGDGNDVLIAGEG-----GAAGSDTLYGD 2007 +EL G D G D+ G G D + G DGND L +G G G D LYG Sbjct: 720 EELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGG 779 Query: 2008 AGDDILVASLTGPSQLSGGAGGDTFRIGPSGGLHTIVR 2045 G+D L+ G + L+GG G D F++ + ++ Sbjct: 780 DGNDKLIGV-AGNNYLNGGDGDDEFQVQGNSLAKNVLF 816 Score = 55.7 bits (134), Expect = 3e-09 Identities = 36/129 (27%), Positives = 58/129 (44%), Gaps = 5/129 (3%) Query: 495 RDLALGADGADVLNTGAGQDFIFAGRGNDILAGGDGNDTLLGGLGSDTYQFTGGFGRDYV 554 D+ GADG D++ G D ++ +GND L+GG+G+D L GG G+D G G +Y+ Sbjct: 737 TDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDK--LIGVAGNNYL 794 Query: 555 LDQDGLGAIQIDGKTLG-DAKSAGKADVWVADLDGQRV--GLAVYNDAASTTGKKLVITR 611 DG Q+ G +L + GK + + +G + G + G + Sbjct: 795 NGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYL 854 Query: 612 AGNVADTIT 620 +G I Sbjct: 855 SGYGHHIID 863 Score = 54.6 bits (131), Expect = 7e-09 Identities = 63/271 (23%), Positives = 93/271 (34%), Gaps = 29/271 (10%) Query: 1751 AGSDTVYGGVGNDTIDGGEGADMLYGGAGDDALTDARGDNTFDAGDGNDRITGMGTSVDA 1810 G D V+ G+ I G+G D++Y D G +AG+ D Sbjct: 618 DGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVT---RVLGGDV 674 Query: 1811 GAGDDVVEVPGARVKLGTGSDTLVVRRSA-GPVGATLLVDGQTQN------GSGRTVRFA 1863 +VV+ V +G ++ R + L + G+ R +F Sbjct: 675 KVLQEVVKE--QEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFF 732 Query: 1864 AGLTPAQVGISSVPGEGGRKDLLVTWAGEGNAGTQELRILGFMDFAEGQRGLRFVFDDAP 1923 + + DL+ EGN G L D G G ++ Sbjct: 733 GS------KFTDIFHGADGDDLI-----EGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDG 781 Query: 1924 QTLWSWGDVFNRANSGTPGDDALR---GTPGDDELRGLAGNDTIDGLAGNDMLDGGAGAD 1980 N N G GDD + + + L G GND + G G D+LDGG G D Sbjct: 782 NDKLIGVAGNNYLNGGD-GDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDD 840 Query: 1981 TLRGGDGNDVLIAGEGGAAGSDTLYGDAGDD 2011 L+GG GND+ G G + D G + Sbjct: 841 LLKGGYGNDIYRYLSG--YGHHIIDDDGGKE 869 Score = 53.0 bits (127), Expect = 2e-08 Identities = 45/192 (23%), Positives = 62/192 (32%), Gaps = 15/192 (7%) Query: 1178 GGEGDDTLVGGGGADVLLGGAGADILEGD---------DAADQVDAKWHGADRLDGGAGN 1228 G+GDD + G+ + G G D++ D D +A + R+ GG Sbjct: 616 LGDGDDKVFLSAGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLGGDVK 675 Query: 1229 DSMYGGGGDDVLAGGEGDDWLAGEDEHAVDAVSTLTGNDTLD------GGVGNDTLVGGN 1282 +V G + E LT D L G D G Sbjct: 676 VLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSK 735 Query: 1283 GNDALMGGEGRDTLYGGAGHDTLIGGAGADLLDGGLGNDTYVIDAADLPEGSSDAAELLR 1342 D G +G D + G G+D L G G D L GG G+D + L Sbjct: 736 FTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLN 795 Query: 1343 DAGGDDTVMLSG 1354 GDD + G Sbjct: 796 GGDGDDEFQVQG 807 Score = 53.0 bits (127), Expect = 2e-08 Identities = 41/148 (27%), Positives = 54/148 (36%), Gaps = 34/148 (22%) Query: 787 NYNLATSAGR--DAYDRLTQAQQDVGLRVTGAFQAGGNRHGAAGGAGADMLEGGTAAASS 844 +Y G+ D L ++ +G F G G D++EG Sbjct: 699 SYEFTHINGKNLTETDNLYSVEELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDR- 757 Query: 845 RQWLYGEAGDDVLTVGAPVDLSAAIAAGETQAGSGNGFASLSGGRGDDRLLGGGGDDVLY 904 LYG+ G+D L SGG GDD+L GG G+D L Sbjct: 758 ---LYGDKGNDTL----------------------------SGGNGDDQLYGGDGNDKLI 786 Query: 905 GGAGDDTLVGGGGADIILADGNGEALVV 932 G AG++ L GG G D GN A V Sbjct: 787 GVAGNNYLNGGDGDDEFQVQGNSLAKNV 814 Score = 51.9 bits (124), Expect = 5e-08 Identities = 24/61 (39%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 879 GNGFASLSGGRGDDRLLGGGGDDVLYGGAGDDTLVGGGGADIILADGNGEALVVGNAADA 938 +G + G G+DRL G G+D L GG GDD L GG G D L G + G D Sbjct: 743 ADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGND-KLIGVAGNNYLNGGDGDD 801 Query: 939 H 939 Sbjct: 802 E 802 Score = 48.0 bits (114), Expect = 7e-07 Identities = 37/109 (33%), Positives = 44/109 (40%), Gaps = 14/109 (12%) Query: 827 AGGAGADMLEGGTA-----AASSRQWLYGEAGDDVLTVGAPVDLSAAIAAGETQAGSGNG 881 +GG G D L GG + +L G GDD V + + G G Sbjct: 768 SGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQG-------NSLAKNVLFGGKG 820 Query: 882 FASLSGGRGDDRLLGGGGDDVLYGGAGDDTLV--GGGGADIILADGNGE 928 L G G D L GG GDD+L GG G+D G G II DG E Sbjct: 821 NDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKE 869 Score = 44.6 bits (105), Expect = 8e-06 Identities = 31/107 (28%), Positives = 42/107 (39%), Gaps = 4/107 (3%) Query: 495 RDLALGADGADVLNTGAGQDFIFAGRGNDILAGGDGNDTLLGGLGSDTYQFTGGFGRDYV 554 D G+ D+ + G D I GND L G GNDTL GG G D Q GG G D + Sbjct: 728 ADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDD--QLYGGDGNDKL 785 Query: 555 LDQDGLGAIQIDGKTLGDAKSAGKADVWVADLDGQRVGLAVYNDAAS 601 + G ++G D + L G + +Y + Sbjct: 786 I--GVAGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGA 830 Score = 43.0 bits (101), Expect = 2e-05 Identities = 23/63 (36%), Positives = 36/63 (57%), Gaps = 5/63 (7%) Query: 2346 GNGANNVIVGNAGSNVLDGKEGLDRLEGGAGDDIYVDMAGDAYAINKDEIVEQANGGNDT 2405 G N+ + G+ G+++LDG EG D L+GG G+DIY ++G + I++ G D Sbjct: 817 GGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGH-----HIIDDDGGKEDK 871 Query: 2406 LLL 2408 L L Sbjct: 872 LSL 874 Score = 42.3 bits (99), Expect = 5e-05 Identities = 26/97 (26%), Positives = 40/97 (41%), Gaps = 7/97 (7%) Query: 1745 DTVDALAGSDTVYGGVGNDTIDGGEGADMLYGGAGDDALTDARG---DNTFDAGDGNDRI 1801 + + G+D +YG G D +DGGEG D+L GG G+D G D G D++ Sbjct: 813 NVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYRYLSGYGHHIIDDDGGKEDKL 872 Query: 1802 TGMGTSVD----AGAGDDVVEVPGARVKLGTGSDTLV 1834 + G+D++ G L G + Sbjct: 873 SLADIDFRDVAFKREGNDLIMYKGEGNVLSIGHKNGI 909 Score = 40.3 bits (94), Expect = 2e-04 Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 13/92 (14%) Query: 2346 GNGANNVIVGNAGSNVLDGKEGLDRLEGGAGDDIYVDMAGDAYAIN---KDEIVEQANG- 2401 GN N+ + G+ G++ L G G D+L GG G+D + +AG+ Y DE Q N Sbjct: 751 GNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGNDKLIGVAGNNYLNGGDGDDEFQVQGNSL 810 Query: 2402 ---------GNDTLLLDAKSRSLADNVENLVL 2424 GND L + L + +L Sbjct: 811 AKNVLFGGKGNDKLYGSEGADLLDGGEGDDLL 842 Score = 37.3 bits (86), Expect = 0.001 Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%) Query: 887 GGRGDDRLLGGGGDDVLYGGAGDDTLVGGGGADIILADGNGEALVVGNAAD 937 G + D G GDD++ G G+D L G G D + + GNG+ + G + Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTL-SGGNGDDQLYGGDGN 782 Score = 36.5 bits (84), Expect = 0.003 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 2/64 (3%) Query: 2143 DDRLVGGAGDDVLSGRGGNDVLSGGAGFDTLAGGAGDDAYLVGRGDGRDVITEAGGSDTL 2202 D+ G D+ G G+D++ G G D L G G+D L G G+G D + G+D L Sbjct: 728 ADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGND-TLSG-GNGDDQLYGGDGNDKL 785 Query: 2203 RFGA 2206 A Sbjct: 786 IGVA 789 Score = 35.7 bits (82), Expect = 0.005 Identities = 46/240 (19%), Positives = 81/240 (33%), Gaps = 50/240 (20%) Query: 2342 IAGVGNGANNVIVGNAGSNVLDGKEGLDRLEGGAGDDIYV-----------------DMA 2384 + +G+G + V + AGS + +G D + D Y+ + Sbjct: 613 ESHLGDGDDKVFLS-AGSANIYAGKGHDVVYYDKTDTGYLTIDGTKATEAGNYTVTRVLG 671 Query: 2385 GDAYAINKDEIVEQANGGNDTLLLDAKSRSLAD-NVENLVLVDWTNTTRVV----PVDSY 2439 GD + + ++ + G T +S N +NL D + + D + Sbjct: 672 GDVKVLQEVVKEQEVSVGKRTEKTQYRSYEFTHINGKNLTETDNLYSVEELIGTTRADKF 731 Query: 2440 YGFQSSSLLYDGRSDDTRV------RLSGNALDNVIDATNQGRISTMMMRDRSDAFGGLV 2493 +G + + + + DD RL G+ ++ + N G Sbjct: 732 FGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGN----------------GDDQ 775 Query: 2494 LDGAGGNDTLIGGVEDDFYLVDSAGDKVVETGVDANGKQV----SVNDTIVSSSVSVDLS 2549 L G GND LIG + YL GD + ++ K V ND + S + L Sbjct: 776 LYGGDGNDKLIGV-AGNNYLNGGDGDDEFQVQGNSLAKNVLFGGKGNDKLYGSEGADLLD 834 Score = 34.6 bits (79), Expect = 0.010 Identities = 18/65 (27%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 2142 SDDRLVGGAGDDVLSGRGGNDVLSGGAGFDTLAGGAGDDAYLVGRGDGRDVITEAGGSDT 2201 S + L+G D G D+ G G D + G G+D +G+ D ++ G D Sbjct: 718 SVEELIGTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGN--DTLSGGNGDDQ 775 Query: 2202 LRFGA 2206 L G Sbjct: 776 LYGGD 780 Score = 34.6 bits (79), Expect = 0.010 Identities = 41/211 (19%), Positives = 67/211 (31%), Gaps = 54/211 (25%) Query: 2346 GNGANNVIVGNAGSNVLDGKEGLDRLEGGAGDDIYVDMAGDAYAINKDEIVEQANGGNDT 2405 G+ ++ G G ++++G +G DRL G G+D GD D++ GND Sbjct: 733 GSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGD------DQLYGGD--GNDK 784 Query: 2406 LLLDAKSRSLADNVENLVLVDWTNTTRVVPVDSYYGFQSSSLLYDGRSDDTRVRLSGNAL 2465 L+ G ++ L G DD + Sbjct: 785 LI---------------------------------GVAGNNYLNGGDGDDEFQVQGNSLA 811 Query: 2466 DNVIDATNQGRISTMMMRDRSDAFGGLVLDGAGGNDTLIGGVEDDFYLVDSAGDKVVETG 2525 NV+ G+ + + G +LDG G+D L GG +D Y S G Sbjct: 812 KNVLF---GGKGNDKLYGSE----GADLLDGGEGDDLLKGGYGNDIYRYLS------GYG 858 Query: 2526 VDANGKQVSVNDTIVSSSVSVDLSAVANVEH 2556 D + + + A + Sbjct: 859 HHIIDDDGGKEDKLSLADIDFRDVAFKREGN 889 Score = 33.0 bits (75), Expect = 0.024 Identities = 16/49 (32%), Positives = 24/49 (48%) Query: 3132 QKFAVTVQSSTITGTSRNDTLTGTTGNDTIDGLAGADTMTGLAGDDTYI 3180 Q ++ + + G ND L G+ G D +DG G D + G G+D Y Sbjct: 804 QVQGNSLAKNVLFGGKGNDKLYGSEGADLLDGGEGDDLLKGGYGNDIYR 852 Score = 33.0 bits (75), Expect = 0.024 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Query: 887 GGRGDDRLLGGGGDDVLYGGAGDDTLVGGGGADIILADGNGEALVVGNAADA-HGTGAND 945 G D+ G D+ +G GDD + G G D + D + L GN D +G ND Sbjct: 724 GTTRADKFFGSKFTDIFHGADGDDLIEGNDGNDRLYGDKGNDTLSGGNGDDQLYGGDGND 783 Query: 946 PATG 949 G Sbjct: 784 KLIG 787
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 369 bits (949), Expect = e-126 Identities = 158/471 (33%), Positives = 254/471 (53%), Gaps = 3/471 (0%) Query: 21 LLQRYADIFRAAWAQRAALAGPPWLADERAFLPAALSLQETPVHPAPRRLAWLVMALFAI 80 L RY ++ W R L P DE FLPA L L ETPV PR +A+ +M I Sbjct: 11 FLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVI 70 Query: 81 ALVWSIFGRIDIVAVAPGRIIVSDRTKLVQPLENSVVRRVLVREGDHVEAGQPLLELDPT 140 A + S+ G+++IVA A G++ S R+K ++P+ENS+V+ ++V+EG+ V G LL+L Sbjct: 71 AFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL 130 Query: 141 AAHADRTSFGEAHRAAESESLRVRALQATLAGEAGPGTKLPRWSPQDIPAAWSARERTDA 200 A AD + A E R + L ++ P KLP + S E Sbjct: 131 GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP---DEPYFQNVSEEEVLRL 187 Query: 201 QAQLLAEWSDITARTARLDAERQRREAEIATVRAMVAKLETTLPVVRQREADFQTLAAQG 260 + + ++S + + + ++ AE TV A + + E V + R DF +L + Sbjct: 188 TSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ 247 Query: 261 FMSGHATQDRMRERVEMERDLATQQARLQEALATLAEARQARMSYLAETRRALSERQAQA 320 ++ HA ++ + VE +L +++L++ + + A++ + + ++ Q Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQT 307 Query: 321 DLKREQNAQELSKAERRERLATLAAPVSGTVQQLAAHTEGGVVTEAQVLMVIVPDGAQVS 380 EL+K E R++ + + APVS VQQL HTEGGVVT A+ LMVIVP+ + Sbjct: 308 TDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLE 367 Query: 381 AEVTLENKDIGFVEPGQDVTIKLETFPFTRYGTVPAQVETVTRDAVNDEKRGAIFPALLR 440 ++NKDIGF+ GQ+ IK+E FP+TRYG + +V+ + DA+ D++ G +F ++ Sbjct: 368 VTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIIS 427 Query: 441 LGTGHIAVDGKDIRLAPGMNLTAEIKTGQRRVIDYLLSPIQKAGSESLRER 491 + ++ K+I L+ GM +TAEIKTG R VI YLLSP++++ +ESLRER Sbjct: 428 IEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLRER 478
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.3 bits (65), Expect = 0.032 Identities = 8/29 (27%), Positives = 11/29 (37%) Query: 362 KATAGQAPAPPPHPPPSPAPAPPPKPASK 390 KA+ Q P P P P+ +K Sbjct: 462 KASDSQTPDAKPGNKAVPGKGQAPQAGTK 490
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 42.0 bits (98), Expect = 2e-06 Identities = 34/117 (29%), Positives = 52/117 (44%), Gaps = 16/117 (13%) Query: 114 AVVRALGVRLAEVLEHLESKRLVHRDIKPANIMFRDDRDPHPVLTDFGI-VRMLDQPT-L 171 ++ + RL +V HL +VH DIKP N++F D PV+ D G+ R +QP Sbjct: 245 GTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVF-DRASGEPVVIDLGLHSRSGEQPKGF 303 Query: 172 THAFMQMGPGTPAYAAPEQLTNDKALIDWRTDQFGVAIVLAECLLG--HHPFLEPGK 226 T +F G A E ++D F V L C+ G +P ++P + Sbjct: 304 TESFKAPELGVGNLGASE-----------KSDVFLVVSTLLHCIEGFEKNPEIKPNQ 349
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 71.5 bits (175), Expect = 4e-16 Identities = 34/118 (28%), Positives = 47/118 (39%), Gaps = 16/118 (13%) Query: 162 INSDILFGTGSATLAGRARGTLSTLAAVLRE---APNGVRVEGYTDNQPIATAQFPSNWE 218 + SD+LF ATL + L L + L V V GYTD I + + N Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY--NQG 272 Query: 219 LSAARAASVVHLFADDGIAPQRLAMVGYGEFRARADNSTEAGRNA---------NRRV 267 LS RA SVV GI +++ G GE N+ + + +RRV Sbjct: 273 LSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV 330
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 8e-23 Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 2/119 (1%) Query: 3 ARILVVDDSASMRQMVSFALTSAGFAVEEAEDGAVALGRAKGQRFNAVVTDVNMPNMDGI 62 A ILV DD A++R +++ AL+ AG+ V + A + VVTDV MP+ + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 SLIRELRQLPDYKFTPMLMLTTESAADKKSEGKAAGATGWLVKPFNPEQLIATVQKVLG 121 L+ +++ P+L+++ ++ + GA +L KPF+ +LI + + L Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature. Length = 483 Score = 32.4 bits (73), Expect = 0.003 Identities = 17/37 (45%), Positives = 23/37 (62%), Gaps = 3/37 (8%) Query: 193 TTFMKALVNHIP--NEERLVTIEDARELFISQPNAVH 227 T +KA+V H N+ RLV I+DAR +F S N V+ Sbjct: 171 TDVIKAIVKHKDRFNDNRLVFIDDARTIF-SLANIVN 206
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 35.5 bits (81), Expect = 1e-04 Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 10/89 (11%) Query: 44 TGLGITTQVELSPNEKILDYSTGFTGGWELTRRENVFYLKPKNVDVD-------TNMMIR 96 T L T ++L +E I +TGF GW + N +++PK+V + N + Sbjct: 59 TSLDNVTVIQLEKDETISYITTGFNKGWSIVPNSNHIFIQPKSVKSNLMFEKEAVNFALM 118 Query: 97 TATHSYILELK---VVATDWQRLEQAKQA 122 T + L+ K V A D + LE+ K+A Sbjct: 119 TRDYQEFLKTKKLIVDAPDPKELEEQKKA 147 Score = 29.8 bits (66), Expect = 0.011 Identities = 11/27 (40%), Positives = 17/27 (62%) Query: 165 YDYDYATRTKKSWLIPSRVYDDGKFTY 191 Y+Y A + ++PS ++DDG FTY Sbjct: 401 YNYYQAPEKRSKHIMPSEIFDDGTFTY 427
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 227 bits (579), Expect = 1e-75 Identities = 53/230 (23%), Positives = 102/230 (44%), Gaps = 12/230 (5%) Query: 19 QVGAAVQKAVNYEVSIADLARRSEKRAWIVATLSMLVTVMTAGGYYYMLPLKEKVPYLVM 78 ++ A ++A ++E A RS+K AW+VA ++ + + PLK PY++ Sbjct: 9 ELKAYFEEAASWERDKLAAAERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVIT 68 Query: 79 ADAYSGTSTIAKLEPNFGGRAISTSEALARSNIARFIIARESFDLSIIGQRDWNTVSAMG 138 D +G ++I G I+ EA+ + +A ++ RE + + + ++ V M Sbjct: 69 VDRNTGEASI--AAKLHGDATITYDEAVRKYFLATYVRYREGWIAAAR-EEYFDAVMVMS 125 Query: 139 STNVVSEYRALHSANNPSRPLNSYGKLRAIRVNILSITLIGGNGKAYTGATVRFQRTVYD 198 + + + +NP P N + V I ++ +GGN A V F + Sbjct: 126 ARPEQDRWSRFYKTDNPQSPQNILANRTDVFVEIKRVSFLGGN-----VAQVYFTKESVT 180 Query: 199 KNSTVSTLLDNKIATMGFVYQDNLEMSDSLRVENPLGFRVTDYRVDNDYS 248 +++ T + +AT+ + D + R +NPLG++V YR D + Sbjct: 181 GSNSTKT---DAVATIKYKV-DGTPSKEVDRFKNPLGYQVESYRADVEVP 226
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 27.5 bits (61), Expect = 0.020 Identities = 11/46 (23%), Positives = 23/46 (50%) Query: 4 PHRGFSLIECSIAVAAFAVALSIALPSLTALRRTHQVRSAMLELAA 49 RGF+L+E + + V S+ +P+L + + A+ ++ A Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVA 51
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.7 bits (111), Expect = 3e-08 Identities = 35/165 (21%), Positives = 58/165 (35%), Gaps = 22/165 (13%) Query: 1 MMKTRIVVAADRTILVEGMVALLQKVPGIEVVGHAEDGLACLQIAARERPDIVLVDVLLP 60 M I+VA D + + L + G +V + + A D+V+ DV++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRA-GYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GLNGIDLTRRLMQRSPN-SRAICIAPSDACTQSSAVFEAGAKAYLARTSRFAELLRAIQC 119 N DL R+ + P+ + A + T A E GA YL + EL+ I Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKA-SEKGAYDYLPKPFDLTELIGIIGR 117 Query: 120 VIQDQTY-----------------ISPQMSRSLIAGLRRAAKADS 147 + + S M + + L R + D Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAM-QEIYRVLARLMQTDL 161
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.4 bits (66), Expect = 0.008 Identities = 11/40 (27%), Positives = 15/40 (37%), Gaps = 1/40 (2%) Query: 134 PLKNIETDFPPVFDRFYRSPALRTCSQCGHLHPAPERYAT 173 L + FP F+R Y + + GHL R A Sbjct: 119 SLADAMKCFPGSFERLYCA-MVAAGETSGHLDAVLNRLAD 157
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.002 Identities = 17/111 (15%), Positives = 31/111 (27%), Gaps = 8/111 (7%) Query: 227 AQQRASEQRVASDLLAQRKHARARGEQVLRAQLQRQQHRQARGARAAGQANQAAILLGGQ 286 AQ R + S++ A + + Q + ++ +A Sbjct: 1063 AQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET------ 1116 Query: 287 KQRSQVSAGRLQQQRQAEQARLSEAVVQAAAQVEVDPAIAALAPTLPANTP 337 ++ Q +Q + QA E DP + P NT Sbjct: 1117 --EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTT 1165
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.9 bits (67), Expect = 0.003 Identities = 15/96 (15%), Positives = 39/96 (40%), Gaps = 10/96 (10%) Query: 43 QDGALALSLVADHDGYVVGHLA----VSPVALSDDSPGWFALGPLAVGPGHQRQGLGARL 98 +D + +S V + + + + + + G+ + +AV ++++G+G L Sbjct: 51 EDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 99 VQAALATLRERGAAGCL----ALGEPA--FFRRLGF 128 + A+ +E G + + A F+ + F Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 26.8 bits (59), Expect = 0.036 Identities = 8/43 (18%), Positives = 15/43 (34%) Query: 7 DSIATAKAKLAEELRKLEEQEANLLEEEASNAFQQASDLLTRF 49 D + +K + L + E + F+ +LLT Sbjct: 303 DLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTAN 345
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 94.0 bits (233), Expect = 3e-25 Identities = 62/200 (31%), Positives = 89/200 (44%), Gaps = 15/200 (7%) Query: 5 KIALVTGATRGIGLETVRQLATAGVHTLLAGCKRDDAVAAALKLQAEGLPVEAIQLDVND 64 KIA +TGA +GIG R LA+ G H + L+AE EA DV D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 65 DISIAAAVGTVEQRHGHLDILINNAGIMIEDMQRAPSQQ-SLEVWKRTFDTNLFAVVEVT 123 +I +E+ G +DIL+N AG+ ++ S E W+ TF N V + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGV----LRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 124 KAFLPLLRRSLAGRIVNVSSILGSLTLHSQPGSPIYDFKIPAYDASKSALNSWTVHLAYE 183 ++ + +G IV V S + G P + AY +SK+A +T L E Sbjct: 125 RSVSKYMMDRRSGSIVTVGS--------NPAGVP--RTSMAAYASSKAAAVMFTKCLGLE 174 Query: 184 LRDTAIKVNTVHPGYVKTDM 203 L + I+ N V PG +TDM Sbjct: 175 LAEYNIRCNIVSPGSTETDM 194
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1047 bits (2710), Expect = 0.0 Identities = 434/1041 (41%), Positives = 641/1041 (61%), Gaps = 20/1041 (1%) Query: 4 SRFFIDRPIFAAVLSIIIFAAGLIAMPLLPISEYPEVVPPSVQVRAVYPGANPKVIAETV 63 + FFI RPIFA VL+II+ AG +A+ LP+++YP + PP+V V A YPGA+ + + +TV Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 ATPLEEAINGVENMMYMKSVAGSDGVLVVTVTFKPGTDPDQAQVQVQNRVSQAQARLPED 123 +E+ +NG++N+MYM S + S G + +T+TF+ GTDPD AQVQVQN++ A LP++ Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 124 VRRQGVTTQKQSPTLTMVVHLTSPKGKYNSLYLSNYATLKVKDELSRLPGVGQIQIFGAG 183 V++QG++ +K S + MV S +S+Y VKD LSRL GVG +Q+FG Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-A 180 Query: 184 DYAMRIWLNPDKVAARGLTASDVVAAIREQNVQVSAGQLGAEPMPNKSDFLLSINAQGRL 243 YAMRIWL+ D + LT DV+ ++ QN Q++AGQLG P SI AQ R Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 244 TTEEEFGNIVIRSGNSGEIVRLSDVARLELGAGNYTLRSQLDNQNAVGMGVFQSPGANAI 303 EEFG + +R + G +VRL DVAR+ELG NY + ++++ + A G+G+ + GANA+ Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 304 ELSDAVRAKMAELERQFPQDMAWSAAYDPTVFVRDSISAVVHTLLEAVLLVVLVVILFLQ 363 + + A++AK+AEL+ FPQ M YD T FV+ SI VV TL EA++LV LV+ LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 364 TWRASIIPLLAVPVSVVGTFAALYLLGFSINTLSLFGLVLAIGIVVDDAIVVVENVER-N 422 RA++IP +AVPV ++GTFA L G+SINTL++FG+VLAIG++VDDAIVVVENVER Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 423 IEEGLSPLAAAHQAMREVSGPIIAIALVLCAVFVPMAFLSGVTGQFYKQFAVTIAISTVI 482 +E+ L P A ++M ++ G ++ IA+VL AVF+PMAF G TG Y+QF++TI + + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 483 SAINSLTLSPALAAMLLKSHDAPKDGPSRLIDRLFGWLFRPFNRFFTTSSHKYQGAVSRA 542 S + +L L+PAL A LLK FGW FN F S + Y +V + Sbjct: 481 SVLVALILTPALCATLLKPV---SAEHHENKGGFFGW----FNTTFDHSVNHYTNSVGKI 533 Query: 543 LGKRGAVFVVYLLLLVGTGFMFKLVPGGFIPTQDKLYLIAGTKLPEGSSLERTNEVIRQI 602 LG G ++Y L++ G +F +P F+P +D+ + +LP G++ ERT +V+ Q+ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 603 TQIALQT--DGVDHAIAFPGLNPLQFTNTPNTGTVFLTLKPFSQRSR---TAAQINAEIN 657 T L+ V+ G + N G F++LKP+ +R+ +A + Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFS--GQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 658 ARISQIQQGFAFAFMPPPILGLGQGSGYSLYIQDRAGLGYGQLQSAVNAMSGAISQTPG- 716 + +I+ GF F P I+ LG +G+ + D+AGLG+ L A N + G +Q P Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 717 MQFPIGTYQANVPQLDAKVDRDKAKAQGVPLTNLFDTLQTYLGSSYINDFNRFGRTYQVI 776 + + Q +VD++KA+A GV L+++ T+ T LG +Y+NDF GR ++ Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 777 AQADGQFRDSVEDIANLRTRNANGDMVPIGSMVTLGQTYGPDPVIRYNGYPAADLIGEAD 836 QAD +FR ED+ L R+ANG+MVP + T YG + RYNG P+ ++ GEA Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 837 PRVLSSTEAMQKLSSMAPQVLPNGMNIEWTDLSYQQSTQGNSALIVFPMAVLLAFLVLAA 896 P SS +AM + ++A + LP G+ +WT +SYQ+ GN A + ++ ++ FL LAA Sbjct: 832 PGT-SSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 897 LYESWTLPLAVILIVPMTLLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNAILIVEFAR 956 LYESW++P++V+L+VP+ ++ L L N+V+ VGL+ +GL+ KNAILIVEFA+ Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 957 EL-EMHGKGIVEAALEACRLRLRPIVMTSIAFIAGTVPLVFGHGAGAEVRSVTGITVFAG 1015 +L E GKG+VEA L A R+RLRPI+MTS+AFI G +PL +GAG+ ++ GI V G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1016 MLGVTLFGLFLTPVFYVALRK 1036 M+ TL +F PVF+V +R+ Sbjct: 1010 MVSATLLAIFFVPVFFVVIRR 1030 Score = 89.9 bits (223), Expect = 3e-20 Identities = 90/514 (17%), Positives = 182/514 (35%), Gaps = 41/514 (7%) Query: 548 AVFVVYLLLLVGTGFMFKLVPGGFIPTQDKLYLIAGTKLPEGSSLERTNEVIRQITQIAL 607 +V+ ++L++ +P PT + P + + V + I Q Sbjct: 11 FAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMN 70 Query: 608 QTDGVDHAIAFPGLNPLQFTNTPNTGTVFLTLKPFSQRSRTAAQINAEINARISQIQQGF 667 D + + + +++ + T+ LT + + Q+ ++ + Q Sbjct: 71 GIDNLMYMSST--------SDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE- 121 Query: 668 AFAFMPPPILGLGQGSG----YSLYIQDRAGLGYGQLQS-AVNAMSGAISQTPGMQFPIG 722 + + + + S + ++ D G + + + +S+ G +G Sbjct: 122 ----VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNG----VG 173 Query: 723 TYQANVPQLDAKV--DRDKAKAQGVPLTNLFDTLQTYL----GSSYINDFNRFGRTYQVI 776 Q Q ++ D D + ++ + L+ G+ Sbjct: 174 DVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 777 AQADGQFRDSVEDIANLRTR-NANGDMVPIGSMVTLGQTYGPDPVI-RYNGYPAADLI-- 832 A +F+ + E+ + R N++G +V + + + VI R NG PAA L Sbjct: 234 IIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 833 ---GEADPRVLSSTEAMQKLSSMAPQVLPNGMNIEWT-DLSYQQSTQGNSALIVFPMAVL 888 G + KL+ + P P GM + + D + + + A++ Sbjct: 293 LATGANALDT--AKAIKAKLAELQP-FFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIM 349 Query: 889 LAFLVLAALYESWTLPLAVILIVPMTLLSALFGVWLTGGDNNVFVQVGLVVLMGLACKNA 948 L FLV+ ++ L + VP+ LL + G N G+V+ +GL +A Sbjct: 350 LVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDA 409 Query: 949 ILIVE-FARELEMHGKGIVEAALEACRLRLRPIVMTSIAFIAGTVPLVFGHGAGAEVRSV 1007 I++VE R + EA ++ +V ++ A +P+ F G+ + Sbjct: 410 IVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ 469 Query: 1008 TGITVFAGMLGVTLFGLFLTPVFYVALRKWVTRR 1041 IT+ + M L L LTP L K V+ Sbjct: 470 FSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 29/186 (15%), Positives = 61/186 (32%), Gaps = 44/186 (23%) Query: 8 FRFPLRTVLAGAVLAVVLAGCGSKAAETGAPPPPSVSVAPVLMKQISQWDEFSGRIEPV- 66 R ++ V+A +L+ G VA +G++ Sbjct: 57 PRLVAYFIMGFLVIAFILSVLG-----------QVEIVATA-----------NGKLTHSG 94 Query: 67 ESVELRPRVSGYIDKVNYTEGAEVKKGDVLFTIDERSYRAEFARANASLVRARTQA---- 122 S E++P + + ++ EG V+KGDVL + A+ + +SL++AR + Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 123 -----------------TLARSEAARARKLSEQQAISTETWEQRRAAADQADADLQAAQA 165 + ++ ++ E + + Q + +L +A Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Query: 166 AVDTAK 171 T Sbjct: 215 ERLTVL 220 Score = 38.3 bits (89), Expect = 4e-05 Identities = 18/102 (17%), Positives = 38/102 (37%), Gaps = 7/102 (6%) Query: 104 YRAEFARANASLVRARTQATLARSEAARARKLSEQ--QAISTETWEQRRAAADQADADLQ 161 ++ A L ++Q SE A++ + Q E ++ R Q ++ Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR----QTTDNIG 312 Query: 162 AAQAAVDTAKLNLDWTRVRAPIDGRAGRAMV-TAGNLVTAGD 202 + + + +RAP+ + + V T G +VT + Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354 Score = 31.0 bits (70), Expect = 0.009 Identities = 12/73 (16%), Positives = 30/73 (41%) Query: 99 IDERSYRAEFARANASLVRARTQATLARSEAARARKLSEQQAISTETWEQRRAAADQADA 158 ++ RAE A + R + + +S L +QAI+ ++ +A Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVN 266 Query: 159 DLQAAQAAVDTAK 171 +L+ ++ ++ + Sbjct: 267 ELRVYKSQLEQIE 279
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.8 bits (80), Expect = 2e-04 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 14/70 (20%) Query: 113 DFIRRRAIRHL-EKGRIAIFAAGTGNPFFTTDSG-------------AALRAIEIGADLL 158 + I+ L E+G I I + G G P D A E+ AD+ Sbjct: 172 GHVEAETIKKLVERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIF 231 Query: 159 LKATKVDGVY 168 + T V+G Sbjct: 232 MILTDVNGAA 241
>PF07520#Virulence protein SrfB Length = 1041 Score = 33.8 bits (77), Expect = 0.001 Identities = 16/62 (25%), Positives = 22/62 (35%) Query: 42 QRREGGAETFAALPNGWWRMDDRALQQAGIDPALLHDAKSGFDAAFYRNDQGQVVLGFCG 101 QR GG E + P+ W R+ L Q + H + D A DQ + Sbjct: 111 QRGAGGEELYDPGPSSWARLRTVELPQPDPETGHTHRVQIALDTALSDQDQSAHYVAPER 170 Query: 102 TD 103 D Sbjct: 171 AD 172
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.9 bits (64), Expect = 0.016 Identities = 24/180 (13%), Positives = 54/180 (30%), Gaps = 9/180 (5%) Query: 20 AADAAREAVHAGRAAALAAARQGMAQAENALGERLRALAAQRPTE----TAPRTAPMRPS 75 + + + + E + + P TA P + + Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKET 1175 Query: 76 RADAVTPLHSASTSGDTSMSDDTQPTPPDQTPAATAQSSGSSQIEAALKAAQAQIDQAMA 135 ++ P+ ++T + P + TP AT Q + +S+ K + +++ Sbjct: 1176 SSNVEQPVTESTTVNTG---NSVVENPENTTP-ATTQPTVNSESSNKPKNRHRRSVRSVP 1231 Query: 136 ASDR-AVRAAMQAATAATAAAGNDQAIDNANQALQQAEQAAAAAVTAAQQQTEQAMAATS 194 + A ++ +T A + + A +A+ A A Q Q Sbjct: 1232 HNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNE 1291
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 144 bits (365), Expect = 5e-40 Identities = 81/332 (24%), Positives = 130/332 (39%), Gaps = 36/332 (10%) Query: 106 LIKRDAARAFAQDRFGRALSIVGVSEEVLTIDEFVEHGAYSRLPVIVRGEFGTEKETVAV 165 L + + +D + +VG S + I + + L +++ GE GT KE VA Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 166 LLHAAAHWREGPFVAIDCAAP----------GDAPAAW----------FKRGAGGTLFLQ 205 LH R GPFVAI+ AA G A+ F++ GGTLFL Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 206 SVDELDDALQRQL-----AGQLCGLGGPWS-AVDGEDSPRVVASTTADLSRRVRAGRFSR 259 + ++ Q +L G+ +GG D R+VA+T DL + + G F Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSD----VRIVAATNKDLKQSINQGLFRE 294 Query: 260 ALLSQLDVLSIELTPLRKRRTDIGFHVEHVLDRHGLDHGQV--VTEVLMDALTHYSWPEN 317 L +L+V+ + L PLR R DI V H + + + V + ++ + + WP N Sbjct: 295 DLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGN 354 Query: 318 LQELERVVLRLAVMTAGRPIGSADIQRHAPRLLEGRVKGAQHDACATMSQPADLPAEPTP 377 ++ELE +V RL + I I+ + + A + S E Sbjct: 355 VRELENLVRRLTALYPQDVITREIIENELRSEI--PDSPIEKAAARSGSLSISQAVEENM 412 Query: 378 PGTPVDWIDGLPHRPGQRLATLHDALRRALVH 409 + D LP P + + L+ Sbjct: 413 RQYFASFGDALP--PSGLYDRVLAEMEYPLIL 442
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 124 bits (314), Expect = 2e-33 Identities = 85/408 (20%), Positives = 176/408 (43%), Gaps = 17/408 (4%) Query: 17 LLWLVSLAIFMQMLDATIVNTALPSMARSLHESPLQMQSVVFSYALAVAMFIPASGWIAD 76 L+WL L+ F +L+ ++N +LP +A ++ P V ++ L ++ G ++D Sbjct: 16 LIWLCILS-FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 77 RFGTRRTFLVAIIVFTLGSLLCAAAQQ-LPQLVAARVVQGIGGAMLLPVGRLAVLKTVAR 135 + G +R L II+ GS++ L+ AR +QG G A + + V + + + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 136 ADFLRAMSFIAIPALIGPLVGPTLGGWLVEVASWHWVFLINLP-IGVIGFIAALKIMPDH 194 + +A I +G VGP +GG + HW +L+ +P I +I +K++ Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPMITIITVPFLMKLLKKE 192 Query: 195 YGDARQRFDLIGYLMLAFGMVALSLALDGISELGLRHAFVMLLAIGGLAALAGYWLHAVS 254 + FD+ G ++++ G+V L S F+++ + + + H Sbjct: 193 -VRIKGHFDIKGIILMSVGIVFFMLFTTSYSIS-----FLIVSVL----SFLIFVKHIRK 242 Query: 255 TPAALFPLALFKVASYRIGILGNLFARVGSGSMPFLIPLLLQVGLGMSPMNAG-LMMVPV 313 L K + IG+L ++P +++ +S G +++ P Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 314 ALAGMAAKRAAVKLVGRFGYRRVLMLNTVLVGLAMASFALVDVGQPLWLRLVQLACFGAV 373 ++ + LV R G VL + + ++ + + + ++ ++ + G + Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 374 NSLQFTVMNTVTLRDLDREQASPGNSLLSMVMMLATEFGAAAAGSLLA 421 + + TV++T+ L +++A G SLL+ L+ G A G LL+ Sbjct: 363 SFTK-TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 1e-16 Identities = 30/123 (24%), Positives = 51/123 (41%) Query: 1058 RILLVEDDPTIAEVIIGLLRAQGHSVVHAPHGLAALTEAADNTFDLALLDLDLPGLDGFA 1117 IL+ +DD I V+ L G+ V + A DL + D+ +P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1118 LARQLRVFGYDMPLVAVTARSDEEAEPTAQEAGFDRFLRKPLTGDMLADTIAEALRRERP 1177 L +++ D+P++ ++A++ A E G +L KP L I AL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 1178 REQ 1180 R Sbjct: 125 RPS 127
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-15 Identities = 29/119 (24%), Positives = 50/119 (42%) Query: 1071 RILLVEDDPTIAEVIVGLLHAQGHSVVHAPHGLAALTEAADNTFDLALLDLDLPGLDGFA 1130 IL+ +DD I V+ L G+ V + A DL + D+ +P + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1131 LARQLRVFGYDMPLIAVTARADEVAEPSAQEAGFDTFLRKPLTGDMLADSIAEALRRKR 1189 L +++ D+P++ ++A+ + A E G +L KP L I AL + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 4e-05 Identities = 56/312 (17%), Positives = 107/312 (34%), Gaps = 41/312 (13%) Query: 76 FTLQVLFTCTFLIMVLLQPVYGALVSRYPRR-VFLPGVYGFFIATLLL-----FYVLFDS 129 +L L+ PV GAL R+ RR V L + G + ++ +VL+ Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 130 GVPG--RGMAFFLWVTVFNLFAVAVFWSFMADVFSNAQARSYYGYIGAAGTLGAFLGPVL 187 + G AV +++AD+ + ++G++ A G GPVL Sbjct: 103 RIVAGITGATG------------AVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVL 150 Query: 188 TRVLVERIGIAHLMLVSAGFLAVCVVCVLRLRLWAVAREQEGQLSSGEVPMGGDVLGGLK 247 ++ H +A L L E + L + Sbjct: 151 GGLMGG-FS-PHAPFFAAAALNGLNFLTGCFLL----PESHKGERRPLRREALNPLASFR 204 Query: 248 LIVREPLLRWLAFMVLFGVGVGTLLYNEQAALVRRLYTDAAAATAYYSSIDLAIN----- 302 ++ L V L + A + ++ + ++ + + I+ Sbjct: 205 WARGMTVVAALMA-----VFFIMQLVGQVPAALWVIFGE---DRFHWDATTIGISLAAFG 256 Query: 303 ALALVLQLLVTRALLSRFGIAPALLIPGVAIMLGYAALAASPLPMMIAIVQVITRSSEFA 362 L + Q ++T + +R G AL++ +A GY LA + M + V+ S Sbjct: 257 ILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLAS--GG 314 Query: 363 LAKPARETLYTR 374 + PA + + +R Sbjct: 315 IGMPALQAMLSR 326
>BACINVASINC#Salmonella/Shigella invasin protein C signature. Length = 409 Score = 29.5 bits (65), Expect = 0.006 Identities = 25/97 (25%), Positives = 40/97 (41%), Gaps = 6/97 (6%) Query: 69 RETAKSKRQAGDLAGAAAALDQALGLVSGDPAILQERAEVSVLQADWPAAERLAKQAIDL 128 R A+ + GDL + + S A QER+E + Q + A + +A + Sbjct: 315 RIDARKMQMTGDLIMKNSVTVGGIAGASRQYAATQERSEQQISQVNNRVASTASDEARES 374 Query: 129 GSKTGPLCRRHWATIEQSRLARGEKENAASAKAQIAG 165 K+ L + T+E ++ ASA A IAG Sbjct: 375 SRKSTSLIQEMLKTMESI------NQSKASALAAIAG 405
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 0.002 Identities = 21/95 (22%), Positives = 27/95 (28%), Gaps = 6/95 (6%) Query: 470 EAQRQVGSLLKPFVYMLALALASPDRWALSSWVDDSPVTVQLSRGKTWSPGNSDNRSHGT 529 + + LLKP L AL S A D+ R W Sbjct: 439 RLRLRGRWLLKPRRAALIEALRSAPALAGCVAFDELREQPVAVRAFPWRKAPGPLEDADV 498 Query: 530 VRLVDALAHSYNQATVRVGMQVGADRIAQLIQVLA 564 +RL D + +Y A Q I V A Sbjct: 499 LRLADYVETTYGTGEAS------AQTTEQAINVAA 527
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 3e-05 Identities = 48/250 (19%), Positives = 90/250 (36%), Gaps = 49/250 (19%) Query: 567 HHRVVGQNEAIKVVSDAVRRSRAGLSDPNRPSGSFLFLGPTGVGKTELCKALADFLFDST 626 +VG++ A++ + + R +D + + G +G GK + +AL D+ Sbjct: 136 GMPLVGRSAAMQEIYRVLAR--LMQTD-----LTLMITGESGTGKELVARALHDYGKRRN 188 Query: 627 EAMIRIDMSEFMEKHSVARLIGAPPGYVGYEEGGYLTEAVRRRPYSL-------ILLDEV 679 + I+M+ + L G+E+G + T A R + LDE+ Sbjct: 189 GPFVAINMAAIPRDLIESEL-------FGHEKGAF-TGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 680 EKAHPDVFNILLQVLDDG---RLTDGQGRTVDFRNTVIVMTSNLGSHQIQELSGDDSAEA 736 D LL+VL G + D R IV +N D ++ Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN-----------KDLKQS 286 Query: 737 YTQMKAAVMGVVQAHFRPEFINRLDDIVVFHPLDKAQIKSIARIQLQGLEKRLAERGLKL 796 + Q FR + RL+ + + P + + + I + +++ E Sbjct: 287 ----------INQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVK 336 Query: 797 DLDDAALEVL 806 D ALE++ Sbjct: 337 RFDQEALELM 346 Score = 34.4 bits (79), Expect = 0.002 Identities = 18/90 (20%), Positives = 33/90 (36%), Gaps = 10/90 (11%) Query: 136 IEAAIDKLRGGET-------VQSENAEEQRQALEKYTIDLTARAESG-KLDPVIGRDEEI 187 AI G +E +AL + + + P++GR + Sbjct: 87 FMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAM 146 Query: 188 RRTIQVLQRRTKNN-PVLI-GEPGVGKTAI 215 + +VL R + + ++I GE G GK + Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELV 176
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 42/167 (25%), Positives = 75/167 (44%), Gaps = 14/167 (8%) Query: 1 MQK-RILIVDDEPAIRDMVAFALRKGEFEPIHAGDAREAQTAIADRVPDLILLDWMLPGT 59 M IL+ DD+ AIR ++ AL + ++ +A IA DL++ D ++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 SGLDLARRWRKEQLTREIPIIMLTARGEENDRVGGLEAGVDDYVVKPFSARELLARIRAV 119 + DL R +K + ++P+++++A+ + E G DY+ KPF EL+ I Sbjct: 61 NAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 M-------RRTREDDEDGSVAVGK----LRIDGAAHRVFAGDAPVPI 155 + + +D +DG VG+ I R+ D + I Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMI 165
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 19/98 (19%), Positives = 38/98 (38%), Gaps = 25/98 (25%) Query: 333 LVTNAVRY----TPGGGTVTIRFVREGDGAALAVRDTGYGIPASHLPRITERFYRVSSSR 388 LV N +++ P GG + ++ ++ L V +TG S + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG------------------SLAL 304 Query: 389 SRESGGTGLGLSIVKHILGL---HQARLDIESEVGRGS 423 TG GL V+ L + +A++ + + G+ + Sbjct: 305 KNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 32.3 bits (73), Expect = 0.002 Identities = 24/96 (25%), Positives = 36/96 (37%), Gaps = 19/96 (19%) Query: 174 GAGVAGLQAIATAKRLGAQVEGFDVRPETREQIASLGARFLDLGVSAAGEGGYARQLSDD 233 G G A + +A+ GA + D PE E++ S S E +A D Sbjct: 19 GIGEAVARTLASQ---GAHIAAVDYNPEKLEKVVS----------SLKAEARHAEAFPAD 65 Query: 234 ER-----AEQQRRLAEHLTGVDVVVCTAAVPGRPAP 264 R E R+ + +D++V A V RP Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVL-RPGL 100
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 5e-08 Identities = 18/126 (14%), Positives = 39/126 (30%), Gaps = 3/126 (2%) Query: 17 AALRRAGWDLLGESGLRGLTLRACARRAGVSHAAPAHHFGSLDGLLADVAADGYERMLAR 76 + L + G+ +L A+ AGV+ A HF L +++ + Sbjct: 14 QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGEL 73 Query: 77 ILATQREVDD---PLMGCGLGYIRFALEFPQHFRLMLGLDVRALRWPRLTEASAAAMACL 133 L Q + ++ L ++ + + RL++ + + A L Sbjct: 74 ELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNL 133 Query: 134 RETVRA 139 Sbjct: 134 CLESYD 139
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 29.6 bits (66), Expect = 0.028 Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 2 LDANLKTQLTAYLERVTRPIQINASIDDS-AGSREMLDLLEELVLLSDKISLDIHRDDNQ 60 DAN K + +++E I+ N +D + AG+ E+ + + +L S I + N Sbjct: 109 FDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNL 168 Query: 61 RKPSFALTTPGQ 72 P PG+ Sbjct: 169 LTPVIEKVKPGE 180
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.049 Identities = 11/20 (55%), Positives = 13/20 (65%) Query: 36 LIGASGCGKSTLLRILAGLE 55 L G G GKSTL+ L GL+ Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 362 bits (932), Expect = e-125 Identities = 144/359 (40%), Positives = 194/359 (54%), Gaps = 16/359 (4%) Query: 5 RLLTLPAAQQHALTGNAVRATAHVFEDPSSQALLTHLERVAPSEASVLIVGESGTGKELV 64 R L P + L ++ V + Q + L R+ ++ +++I GESGTGKELV Sbjct: 117 RALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176 Query: 65 ARHIHHRSARARHPFVAVNCGAFSESLVDAELFGHEKGAFTGALSAKAGWFEEANGGTLF 124 AR +H R PFVA+N A L+++ELFGHEKGAFTGA + G FE+A GGTLF Sbjct: 177 ARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLF 236 Query: 125 LDEIGDLPMPIQVKLLRVLQEREVVRLGSRRSVPIDVRVLAATNVPLDHAIQHGYFRQDL 184 LDEIGD+PM Q +LLRVLQ+ E +G R + DVR++AATN L +I G FR+DL Sbjct: 237 LDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDL 296 Query: 185 FYRLNVVGVELKPLRERPGDIPPLIRHFVDIYSQRLGHGRVTISADAEHLLVEYPWPGNI 244 +YRLNVV + L PLR+R DIP L+RHFV + G +A L+ +PWPGN+ Sbjct: 297 YYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNV 355 Query: 245 RELENVIHHTLLIHRDGVVRAEDIRLS------QLRLPGQAGGDPHEDGQALLERAFDSL 298 RELEN++ ++ V+ E I + A +E Sbjct: 356 RELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQY 415 Query: 299 FESAGGALHAT---------VEDQLFRAAYRHCHHNQVKTAALLGLSRNIVRARLIELG 348 F S G AL + +E L AA NQ+K A LLGL+RN +R ++ ELG Sbjct: 416 FASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG 474
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 365 bits (939), Expect = e-119 Identities = 208/678 (30%), Positives = 331/678 (48%), Gaps = 60/678 (8%) Query: 8 WLISATLLLALPAVPMTALHAADAPAVRLQDVDLRAFIQDVSRATGITFIVDTRVQGSVN 67 + ++ + AL P AA+ + + D++ FI VS+ T I+D V+G++ Sbjct: 10 FSLTLLIFAALLFRPA----AAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTIT 65 Query: 68 VARAQAMSEADLLGMLLAVLRANGLIAVSSGPSTYRVIPDDTAAQQPG-----SAANGNL 122 V ++E L+VL G ++ +V+ A +A Sbjct: 66 VRSYDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGD 125 Query: 123 GFATQVFTLQRVDARSAAEILKPLIGRGGVIMAM--PQGNSLLIADYADNLRRIRTLVAQ 180 T+V L V AR A +L+ L GV + N LL+ A ++R+ T+V + Sbjct: 126 EVVTRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVER 185 Query: 181 IDTDR-AAIDTVTLRNSSAQELARTLTSLF----GQGGERSNVLSVLPVDSSNSLIVRGD 235 +D ++ TV L +SA ++ + +T L S V +V+ + +N+++V G+ Sbjct: 186 VDNAGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGE 245 Query: 236 PALVQRVVRTAVDLDGRAERRGDVSVVRLQHASAEQLLPVLQQLVGQTPGNEAQVGQDTR 295 P QR++ LD + +G+ V+ L++A A L+ VL + T +E Q + Sbjct: 246 PNSRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTG-ISSTMQSEKQAAKPV- 303 Query: 296 LATIDVAAASGAAQTQVIAPAAGKRPVIVRY-PGSNALIINADPETQRALMDVIRQLDVH 354 AA + +I++ +NALI+ A P+ L VI QLD+ Sbjct: 304 --------------------AALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIR 343 Query: 355 REQVLVEAIVVEISDTAAKRLGVQLLLAGRNGTVPLVATQYSGASPGIVPLAAAAAGTRS 414 R QVLVEAI+ E+ D LG+Q A +N + TQ++ + I A A Sbjct: 344 RPQVLVEAIIAEVQDADGLNLGIQW--ANKNAGM----TQFTNSGLPISTAIAGANQYNK 397 Query: 415 GNADDDSVLEQARNVAAQSLLGLSGGLIGLAGQSNDAVFGMIIDAVKSDTGSNLLSTPSI 474 S+ S L G+ Q N + M++ A+ S T +++L+TPSI Sbjct: 398 DGTVSSSLA---------SALSSFNGIAAGFYQGN---WAMLLTALSSSTKNDILATPSI 445 Query: 475 MTLDNEQARILVGQEVPITTGEVLGAANDNPFRTIQRQDVGVELEVRPQINTAGGITLAI 534 +TLDN +A VGQEVP+ TG + DN F T++R+ VG++L+V+PQIN + L I Sbjct: 446 VTLDNMEATFNVGQEVPVLTGSQTTS-GDNIFNTVERKTVGIKLKVKPQINEGDSVLLEI 504 Query: 535 KQEVSAIAGPVSAQSSEL--VFNKRQIETRVVVENGAIVALGGLLDQNDRQTVEKVPLLG 592 +QEVS++A S+ SS+L FN R + V+V +G V +GGLLD++ T +KVPLLG Sbjct: 505 EQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVPLLG 564 Query: 593 DVPGLGALFRHKSRNRDKTNLMVFIRPTIIRDAADAQRMTAPRYTYLRERQLADGDPEAA 652 D+P +GALFR S+ K NLM+FIRPT+IRD + ++ ++ +YT + Q E Sbjct: 565 DIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFNDAQSKQRGKENN 624 Query: 653 LDALVRDYLRAQPPQLPA 670 L +D L P Q A Sbjct: 625 DAMLNQDLLEIYPRQDTA 642
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 42.6 bits (100), Expect = 6e-07 Identities = 40/186 (21%), Positives = 68/186 (36%), Gaps = 22/186 (11%) Query: 80 IVLHGVRVGG-TQAAAYLSGSDGRQGAYRVGDTVAPGLM--VQAIAADHVLLRAGGSVRR 136 + L GV G + + D Q + V + V PG + +I D V+L+ G Sbjct: 95 LSLTGVMAGDDDSRSIAIISKDNEQFSRGVNEEV-PGYNAKIVSIRPDRVVLQYQGRYEV 153 Query: 137 IALSEASAAGAAPPAAATSATAPAIAPAAAQSNVATAADPTAATAVDPQQLLASAGLRAS 196 + L +G+ P A + T + ++ + + Sbjct: 154 LGLYSQEDSGSDGV------------PGAQVNEQLQQRASTTMS-----DYVSFSPIMND 196 Query: 197 AEGGGFTLMPRGDGALLRQAGLAPGDVLTQINGRTL-DAEHLRELQDELRDGQSATLTYR 255 + G+ L P + GL D+ +NG L DAE ++ + + D + TLT Sbjct: 197 NKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAKKAMERMADVHNFTLTVE 256 Query: 256 RDGQTH 261 RDGQ Sbjct: 257 RDGQRQ 262
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 29.2 bits (65), Expect = 0.030 Identities = 13/46 (28%), Positives = 14/46 (30%), Gaps = 3/46 (6%) Query: 55 PPAPAPTPTPAPTPAPTPAP---APSGPAADCPSGFSNVGTIANNT 97 AP P P P P P P P D S + NT Sbjct: 83 KEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENT 128
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 30.6 bits (69), Expect = 0.006 Identities = 11/61 (18%), Positives = 24/61 (39%), Gaps = 3/61 (4%) Query: 25 EQALQPLLDQGWNEQDAIDAVEALVRAHIQQHAQANGLPMPVRV---PALQQDTDASLLA 81 A QP ++ + Q+A++ +R + + + L + R+ LQ + Sbjct: 110 VDAYQPFSEEKISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRI 169 Query: 82 L 82 L Sbjct: 170 L 170
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 56.2 bits (135), Expect = 8e-10 Identities = 59/413 (14%), Positives = 121/413 (29%), Gaps = 46/413 (11%) Query: 579 KGETDSSTSDSSNPQQVLDIQARMQASVAAQARQEREQQDRLAQEQHAAQVREHLQQAQP 638 G D + Q +D + QA + + A P Sbjct: 975 NGRYDLYNPEVEKRNQTVD-TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATP 1033 Query: 639 EREDHSQSEQAVQAHALLEGQRQAA-----QQREQEERQLQDRQAQTSQQRELQ-EREER 692 + +E + Q +E Q A Q RE + + +A T Q E + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETK 1093 Query: 693 DVQERQAQERQAQDNQQ------REQQERQAQEATRGEVQERQAQQAQQQDPSQHASEQA 746 + Q + +E + ++ + Q EV + +Q + +Q+ S+ QA Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQ----------EVPKVTSQVSPKQEQSETVQPQA 1143 Query: 747 DPQPHAPTAALAQQTPQPELQQPDAYQQFETNNQPVGERAAHTTLEPRTPAPG------- 799 +P ++ D Q + + V + +T + Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 800 PGDAQPHQAREAGRALEMQAVESRDASRLPIPAPEGQESGNQPSQSAEADAVPPALHPQV 859 P QP E+ + + S + +P S N S A D Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRS--VPHNVEPATTSSNDRSTVALCDLTS------- 1254 Query: 860 QTQQAEMEPASVREQDVAREREVEPVRVISATTPASEPMIASQSARSSTSERDAGADQPR 919 A + A + Q VA + V A + + + + + + ++ Sbjct: 1255 TNTNAVLSDARAKAQFVA-------LNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNKNY 1307 Query: 920 PSDAPHAYKEAALLPAAHLAQAHEQSLEASAVSRSSVSAQDAENQRTQSTPAQ 972 S + + Q +++ V ++ + + +++T AQ Sbjct: 1308 SSSQYRRFSSKSTQTQLGWDQTISNNVQLGGVFTYVRNSNNFDKATSKNTLAQ 1360 Score = 53.1 bits (127), Expect = 6e-09 Identities = 51/320 (15%), Positives = 92/320 (28%), Gaps = 32/320 (10%) Query: 561 EVQGSRREVPSLGGAPEAKGETDSSTSDSSNPQ----QVLDIQARMQASVAAQARQEREQ 616 EV+ + V + + D + S+N + + A+ + E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 617 QDRLAQ-----EQHA----AQVREHLQQAQPEREDH-SQSEQAVQAHALLEGQRQAAQQR 666 + ++ EQ A AQ RE ++A+ + + +E A E Q ++ Sbjct: 1044 SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET 1103 Query: 667 EQEERQLQDRQAQTSQQRELQEREERDVQERQAQERQAQDNQQREQQERQAQEATRGEVQ 726 E + + E ++ +E Q +Q Q + Q E + ++ Sbjct: 1104 ATVE-------KEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 727 ERQAQQAQQQDPSQHASE--QADPQP---HAPTAALAQQTPQPELQQPDAYQ---QFETN 778 E Q+Q D Q A E QP PE P Q E++ Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESS 1216 Query: 779 NQPVGERAAHTTLEPRTPAP---GPGDAQPHQAREAGRALEMQAVESRDASRLPIPAPEG 835 N+P P P D + + A + G Sbjct: 1217 NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVG 1276 Query: 836 QESGNQPSQSAEADAVPPAL 855 + SQ + + Sbjct: 1277 KAVSQHISQLEMNNEGQYNV 1296
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 27.4 bits (60), Expect = 0.041 Identities = 17/102 (16%), Positives = 41/102 (40%), Gaps = 8/102 (7%) Query: 44 LRDVVAEQLQVVQHAASSADAKVNRVLENALPRLTQLTNQALTQTLEPAAKRFNKEMATA 103 L +++ +Q+ Q ++ ++ L + + NQAL+Q ++ A R Sbjct: 90 LAEMMVKQMTPEQPL--PEESTPAAPMKFPLETVVRYQNQALSQLVQKAVPR------NY 141 Query: 104 DETLQQATRRYAQAQQSLETKITRRMGIASATMLVAGVLGLG 145 D++L ++ + +++ G+ +L L G Sbjct: 142 DDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESG 183
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 854 bits (2207), Expect = 0.0 Identities = 341/1038 (32%), Positives = 546/1038 (52%), Gaps = 27/1038 (2%) Query: 3 LSDLSITRPVMAVVMSLLLIVLGVMSFTRLTLRELPAIDPPIVSVDVEYTGASAAVVESR 62 +++ I RP+ A V++++L++ G ++ +L + + P I PP VSV Y GA A V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 ITQVLEDALAGIEGISTIEARS-RNGSSDISIEFVQSRDVEAAANDVRDAVSRVSDRMPD 121 +TQV+E + GI+ + + + S GS I++ F D + A V++ + + +P Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 QARPPEISKVEADADPILWLNMSSSTMDTLQ--LSDYAERYVVDRFSSLDGVAQVRIGGR 179 + + IS ++ + ++ S T Q +SDY V D S L+GV V++ G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 QRYAMRIWLDRDQLAARELTVADVEAALQNENVELPAGSIESA------QRDFTLRVERS 233 Q YAMRIWLD D L +LT DV L+ +N ++ AG + Q + ++ + Sbjct: 181 Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 YLKPEDFAKLPLNKGEGGYVVRLGDVARVELTSAERRAYFQSNGVPNVGLGIVRNSTANA 293 + PE+F K+ L G VVRL DVARVEL + NG P GLGI + ANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 LDVAREARAQAEEVQKSLPKGTNIFVAFDTTTFIDAAVERVYHTLVEAVVLVLVVIWVFL 353 LD A+ +A+ E+Q P+G + +DTT F+ ++ V TL EA++LV +V+++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 GSARAALIPAVTVPVCLIAAFIALYAFDFSINLLTLLALVLCIGLVVDDAIVVVENIQRR 413 + RA LIP + VPV L+ F L AF +SIN LT+ +VL IGL+VDDAIVVVEN++R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 I-DLGEPPLVAAKRGTGQVAFAVIATTAVLVAVFLPVGFLEGNTGRLFRELAVALAAAVA 472 + + PP A ++ Q+ A++ VL AVF+P+ F G+TG ++R+ ++ + +A+A Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 ISAFVALTLTPMMSSKLLR---AHGQAKPNRFHHWFDGRMQAVSGAYGRSLERHVHRTWI 529 +S VAL LTP + + LL+ A F WF+ Y S+ + + T Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 530 FALLMLLALGASAWLMGRIPSELAPAEDRGNFQIMIDGPEGAGFDYTVGQMHQVEDILRP 589 + L+ L + L R+PS P ED+G F MI P GA + T + QV D Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY--- 596 Query: 590 YVGPDKPIVRANPRVPGGFGSSEEMHTGRVSVFLQDWEKRTRPTTEVADEVQQKLNVLSG 649 Y+ +K V + V G S + + G V L+ WE+R + + L Sbjct: 597 YLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGK 656 Query: 650 VR-ARTQ------VSGGLVRSRGQPFQLVLGGPDYAEIAQWRDRILQRMEANPG-LVGPD 701 +R + + + G + + Q R+++L +P LV Sbjct: 657 IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 702 SDYKETRPQMRVNIDRLRAADLGVPVTAIGGALEALMGSRRVTTFVDNGEEYDVMLQAGR 761 + E Q ++ +D+ +A LGV ++ I + +G V F+D G + +QA Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 762 EGRMSPEDLTAIRVRSNRGELIPLSNLVTLSEVAEAGTLNRFNRLRAITITAGLAPGYPL 821 + RM PED+ + VRS GE++P S T V + L R+N L ++ I APG Sbjct: 777 KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSS 836 Query: 822 GDAIAWAQQAAQEELPEYAQVDWKGESREYQQSGSAVLLTFGMALLVVYLVLAAQFESFA 881 GDA+A + A +LP DW G S + + SG+ ++ +VV+L LAA +ES++ Sbjct: 837 GDAMALMENLA-SKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 882 HPLVIMLTVPLAVLGALVGLWLTGGTLNLFSQIGIVMLVGLAAKNGILIVEFANQLRD-E 940 P+ +ML VPL ++G L+ L +++ +G++ +GL+AKN ILIVEFA L + E Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 941 GRSVHAAIVESASVRLRPILMTSIATVVGAIPLVVAGGPGSASRATIGVVVIFGVSLSTL 1000 G+ V A + + +RLRPILMTS+A ++G +PL ++ G GS ++ +G+ V+ G+ +TL Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1001 LSLYVVPAFYSLIAPFTK 1018 L+++ VP F+ +I K Sbjct: 1016 LAIFFVPVFFVVIRRCFK 1033
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.4 bits (79), Expect = 6e-04 Identities = 14/88 (15%), Positives = 34/88 (38%), Gaps = 6/88 (6%) Query: 72 VVEQVYFDSGDEVKAGQLLLRLRGNSQQAALTAAQATF------EETDQLYRRQLSLVGQ 125 +V+++ G+ V+ G +LL+L +A Q++ + Q+ R + L Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL 165 Query: 126 QLVAKSTVDTQRALRDAAHARVQQMRAE 153 + + + + R+ + E Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKE 193 Score = 34.0 bits (78), Expect = 8e-04 Identities = 33/181 (18%), Positives = 69/181 (38%), Gaps = 24/181 (13%) Query: 99 QAALTAAQATFEETDQLYRRQLSLVGQQLVAKSTVDTQRALRDAAHARVQQMRAEITDRE 158 ++ + +A+ ++ QL++ ++ +Q + T A +Q + I Sbjct: 279 ESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLEL----AKNEERQQASVI---- 330 Query: 159 VRAPFSG-VLGIRQISPGSLITS-STVIATLDDVARMYVDFQVPESQFGLVQLGNAVSGS 216 RAP S V ++ + G ++T+ T++ + + + V V G + +G Sbjct: 331 -RAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIK 389 Query: 217 AAAYPGAQF---QGEVVTI--DSRIDETTRSVT-VRADFP-------NDDRRLRPGMLLD 263 A+P ++ G+V I D+ D+ V V N + L GM + Sbjct: 390 VEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVT 449 Query: 264 V 264 Sbjct: 450 A 450
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 0.001 Identities = 29/225 (12%), Positives = 60/225 (26%), Gaps = 22/225 (9%) Query: 587 LVAQGRVGEAQQLLARTD--------TALGNQLDDPQLLAALAGAHADAGNTQRALVLAQ 638 +V +G +L + + L +L + + + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 639 RLVTGASPRIEDRLQYASVLLRAH------QDAELSAVLRQLQATTMTPEQLRRYQGLRS 692 E+ + + L++ Q + L + +A +T S Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 693 AYTLRQVDALRELGNLEGAYDALSPVLAQQPGNRDAQAALARLYAAAGEHRQALAIYQQI 752 ++D L L A VL Q+ +A L + + + ++ Sbjct: 231 RVEKSRLDDFSSL--LHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEE 288 Query: 753 LQRQPSDLDTLT------AAANSAAAQSDLRDAERYLQRALAQAP 791 Q N +L E Q ++ +AP Sbjct: 289 YQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAP 333
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.8 bits (85), Expect = 1e-05 Identities = 15/59 (25%), Positives = 25/59 (42%) Query: 67 DEAHVLNVCIAPEAQSQGHGRVLLRALIKGACDRGARRAFLEVRPSNPSAIALYHSEGF 125 A + ++ +A + + +G G LL I+ A + LE + N SA Y F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 31.1 bits (70), Expect = 0.004 Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 5/80 (6%) Query: 197 ILTTILLFLAPVFYPVTSLPEGLRRWIYLNPLTFIIEQTRNVLIWG----IAPDFVGLFK 252 ++ T +LFL+ +PV LP + PL+ I+ R +++ + L Sbjct: 184 LVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCI 243 Query: 253 YIVFAAFLAWLGYLCFQKLR 272 YIV FL+ L + LR Sbjct: 244 YIVIPFFLS-TALLRRRLLR 262
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 34.1 bits (78), Expect = 6e-04 Identities = 23/95 (24%), Positives = 40/95 (42%), Gaps = 20/95 (21%) Query: 215 GKAALSGDAAGQAKALAEYL--NIGKKGRVSIVGFDTDA--------AIAKKRAEALRDA 264 KA L + L L K G V ++G+ TD ++++RA+++ D Sbjct: 226 NKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGY-TDRIGSDAYNQGLSERRAQSVVDY 284 Query: 265 LVAGGVSASRL---------QVSGTKGAASKARAA 290 L++ G+ A ++ V+G K RAA Sbjct: 285 LISKGIPADKISARGMGESNPVTGNTCDNVKQRAA 319
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.3 bits (58), Expect = 0.033 Identities = 11/83 (13%), Positives = 24/83 (28%), Gaps = 3/83 (3%) Query: 43 ATQADADQYAPDLVNLARQELMQAQQAQLDKRQRKQVPQIALRAAADADLAKARSEEAV- 101 A A+AD L + Q + ++P++ L + Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 102 --VTAQLEQRRKEVAQLQNTLNT 122 + Q + + Q + L+ Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDK 211
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 66.6 bits (162), Expect = 5e-13 Identities = 56/336 (16%), Positives = 111/336 (33%), Gaps = 31/336 (9%) Query: 564 PRSSDGSADADTSSSAPSNQHALD---VQARGQAASAAQERQERQQEDRQAQDQQLAQAR 620 P + DT++ N D V + + + E + A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 621 AHTRQEQTSHEERAQDAQALQAHALQELRRQESQQLEQQERQTQAAQQREQVQQQAHDTQ 680 ++ +T E+ QDA E Q + ++ + +A Q +V Q +T Sbjct: 1043 NSKQESKTV-EKNEQDAT--------ETTAQNREVAKEAKSNVKANTQTNEVAQSGSET- 1092 Query: 681 QRERAQQQAQETQQREQETRQAQDDQQSQQERLQAQDAQHPEQ---QPLHAQAAPQREQE 737 +E + +ET E+E +A+ + + QE + P+Q + + QA P RE + Sbjct: 1093 -KETQTTETKETATVEKE-EKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREND 1150 Query: 738 PENEAVSHEPSSLHAQDTSPRQPEQRSTPDDLAQRPQAQLAEPAQAQASDVAQQRPQSQH 797 P EP S QP + ++ + + + E + + P++ Sbjct: 1151 PTVNI--KEPQSQTNTTADTEQPAKETSSN-----VEQPVTESTTVNTGNSVVENPENTT 1203 Query: 798 AQEERPQEAQQQTAQSAAIAQSAPANQQQVADLHSGQRPMTAQASDAQQNAPAQQPEQPA 857 +P + + + +++ V + P T ++D A Sbjct: 1204 PATTQPTVNSESSNKPKN------RHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNT 1257 Query: 858 DAYLAQAALPPSAPSFATAVAAEQRDEQEARTPQAQ 893 +A L+ A + A Q Q + Q Sbjct: 1258 NAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 44.7 bits (105), Expect = 3e-06 Identities = 46/267 (17%), Positives = 97/267 (36%), Gaps = 29/267 (10%) Query: 735 EQEPENEAVSHEPSSLHAQDTSPRQPEQRSTPDDLAQRPQAQLAEPAQAQASDVAQQRPQ 794 E E N+ V + + P S +++A+ +A + PA A S+ + + Sbjct: 984 EVEKRNQTVDTTNITT-PNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 795 SQHAQEERPQEAQQQ-----TAQSAAIAQSA----PANQQQVADLHSGQRPMTAQASDAQ 845 + QE + E +Q TAQ+ +A+ A AN Q SG Q ++ + Sbjct: 1043 NSK-QESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 846 QNAPAQQPEQPADAYLAQAALPPSAPSFATAVAAEQRDEQEARTPQAQALEAPDPAAALP 905 + + E+ A + P + V+ +Q + E PQA+ DP Sbjct: 1102 E-TATVEKEEKAKVETEKTQ---EVPKVTSQVSPKQE-QSETVQPQAEPARENDPTVN-- 1154 Query: 906 VSAHLAQATGPSLDLPSAGRSAEAPEGAADAREPLSASLADEHDRPAAVPADPNSWEEIE 965 + + + + A+ E +++ +P++ S + + E Sbjct: 1155 ----IKEPQSQTNTTADTEQPAK--ETSSNVEQPVTESTTVN-----TGNSVVENPENTT 1203 Query: 966 RSMRELRIQLEQELETENRVAEARQAR 992 + + + E + +NR + ++ Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSV 1230
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 8e-05 Identities = 17/30 (56%), Positives = 17/30 (56%) Query: 31 PQGDGGGGGDGGGGGGGGGGGGGGGGGGGG 60 P G G G G GGG G G GGG G GGG Sbjct: 45 PWGGGSGSGIHWGGGSGHGNGGGNGNSGGG 74 Score = 30.5 bits (68), Expect = 2e-04 Identities = 15/27 (55%), Positives = 15/27 (55%) Query: 33 GDGGGGGDGGGGGGGGGGGGGGGGGGG 59 GGG G G GGG G GGG G GG Sbjct: 55 HWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 30.1 bits (67), Expect = 3e-04 Identities = 16/28 (57%), Positives = 16/28 (57%) Query: 33 GDGGGGGDGGGGGGGGGGGGGGGGGGGG 60 G GGG G G GGG G GGG G GG Sbjct: 53 GIHWGGGSGHGNGGGNGNSGGGSGTGGN 80 Score = 29.3 bits (65), Expect = 5e-04 Identities = 14/29 (48%), Positives = 14/29 (48%) Query: 30 GPQGDGGGGGDGGGGGGGGGGGGGGGGGG 58 G GG G GGG G GGG G GG Sbjct: 53 GIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 28.5 bits (63), Expect = 0.001 Identities = 16/31 (51%), Positives = 16/31 (51%) Query: 30 GPQGDGGGGGDGGGGGGGGGGGGGGGGGGGG 60 G G G G G G G GGG G GGG G G Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG 78 Score = 26.2 bits (57), Expect = 0.006 Identities = 14/29 (48%), Positives = 15/29 (51%) Query: 25 GPAMQGPQGDGGGGGDGGGGGGGGGGGGG 53 G G G G GGG+G GGG G GG Sbjct: 53 GIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 25.8 bits (56), Expect = 0.011 Identities = 14/38 (36%), Positives = 16/38 (42%) Query: 23 ANGPAMQGPQGDGGGGGDGGGGGGGGGGGGGGGGGGGG 60 ++G GGG G GGG G G GGG G Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS 71
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 30.6 bits (68), Expect = 0.006 Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 2/91 (2%) Query: 67 TLQRREHALDDLVREQLQLLQSAVNSADQRVNRVVESALPRLTQLSNQALTQTLEPAAER 126 T + L++ +E + +N A N V + L + +N TLE A E Sbjct: 255 TDSKSAETLENARKEAFAQSKDVLNMAKAHSNSVARTTLETAEEHANSVARTTLETAEEH 314 Query: 127 FNKKMATAEQTVQQATRRYAHAQHSLETTTT 157 NKK +AE + + H+L+T + Sbjct: 315 ANKK--SAEALASANVYADSKSSHTLKTANS 343
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 37.6 bits (87), Expect = 7e-06 Identities = 15/61 (24%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 82 SVEHSIYVHRDHRGKGLGRLLLQALIAAAQARGVHVLVGGIDASNQASIALHEQFGFTHA 141 +E I V +D+R KG+G LL I A+ L+ N ++ + + F Sbjct: 91 LIED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIG 149 Query: 142 G 142 Sbjct: 150 A 150
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 56.8 bits (137), Expect = 2e-11 Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 12/115 (10%) Query: 124 GATVLYIEDSRVVAEATKRMLERQSLKVVHVLTAEDAFALLTAESLGRTERRIDVVLTDV 183 GAT+L +D + + L R V A + + A D+V+TDV Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-------GDLVVTDV 55 Query: 184 TLKGELNGRDVVERIRIDFAYGKRRLPVLVMTGDTNPRNQSDLLRAGANDLVQKP 238 + E N D++ RI+ LPVLVM+ GA D + KP Sbjct: 56 VMPDE-NAFDLLPRIKKARP----DLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105 Score = 45.6 bits (108), Expect = 8e-08 Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 4/82 (4%) Query: 2 VVDGSKLVRKLIADVLKRDLPNVQVIGCSNIAEARQALEAGAVDLVTTSLSLPDGDGLTL 61 V D +R ++ L R V SN A + + AG DLV T + +PD + L Sbjct: 8 VADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 62 ARSVRETAGQAYVPVIVVSGDA 83 +++ + +PV+V+S Sbjct: 66 LPRIKKA--RPDLPVLVMSAQN 85
>PF01540#Adhesin lipoprotein Length = 475 Score = 37.8 bits (87), Expect = 5e-05 Identities = 33/102 (32%), Positives = 49/102 (48%), Gaps = 13/102 (12%) Query: 34 MRKPWATLLTIVVMALALALPLGLSIALDNVKLLAGSVQQSREINLFLKVDVAADAAQAL 93 M+K +T+ +A LP+ +I+ ++ KL E N K D A A AL Sbjct: 1 MKKSKKIFITLCGIAATAVLPIA-TISCNDDKL--------AEKNGKEKADAALKQANAL 51 Query: 94 AGELRARPDVAKVTLRTPEQGLAELRESAKLDEAADALGDNP 135 A EL+ PD +K+ L T + +AE +S K A + GD P Sbjct: 52 AEELKKNPDYSKI-LETLNKEIAEATKSFK---EAGSYGDYP 89
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.009 Identities = 14/84 (16%), Positives = 24/84 (28%), Gaps = 3/84 (3%) Query: 462 PRRKPRVEGQAPAAAASTEHPVVAAVAAQAPSAGVADAERAPRKRRRRRNGRPVEGAEPA 521 P+++ Q A A P V Q+ + AD E+ + N Sbjct: 1131 PKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQP--AKETSSNVEQPVTESTT 1188 Query: 522 LASTPVPAPAAPRKPTQVVAKPVR 545 + + P T +P Sbjct: 1189 VNTGNSV-VENPENTTPATTQPTV 1211
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.7 bits (129), Expect = 4e-10 Identities = 31/209 (14%), Positives = 69/209 (33%), Gaps = 25/209 (11%) Query: 90 ALEQARAALAERRATLTQLRREIARDRSLQDLVAAEDAEVRRSNVQKAQAAVATAQSAVD 149 +A L ++ L Q+ EI + LV +++ + + Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA 319 Query: 150 LAQLNLDRTQVRSPADGRVSDRTVR-VGDYVNAGRPVVAVL-DTGSFRVDGYFEETRLQG 207 + + +R+P +V V G V ++ ++ + + V + + Sbjct: 320 KNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGF 379 Query: 208 VHPGQRVDVQLMGEPVT----LQGHVQSIAAGIEDRYRSGSAGALPNVTPAFDWVRLAQR 263 ++ GQ +++ P T L G V++I + R G L Sbjct: 380 INVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG----------------LVFN 423 Query: 264 IPVRIVLDRVPA---HVQLIAGRTATVSI 289 + + I + + ++ L +G T I Sbjct: 424 VIISIEENCLSTGNKNIPLSSGMAVTAEI 452 Score = 42.5 bits (100), Expect = 1e-06 Identities = 21/168 (12%), Positives = 57/168 (33%), Gaps = 19/168 (11%) Query: 14 PALLTLSMVVVAALVLQHLWRYYMQAPWTRDAHVGADVV------QVAPDVSGLVESVAV 67 ++ ++ LV+ + A + ++ P + +V+ + V Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVL--GQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIV 112 Query: 68 ADNQPVRRGQLLFVVDRARYAIALEQARAALAERRATLTQLRREIARD----RSLQDLVA 123 + + VR+G +L + + +++L + A L Q R +I L +L Sbjct: 113 KEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ--ARLEQTRYQILSRSIELNKLPELKL 170 Query: 124 AEDAEVRRSNVQKAQAAVATAQSAVD-----LAQLNLDRTQVRSPADG 166 ++ + + ++ + + Q L+ + R+ Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLT 218
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.3 bits (66), Expect = 0.049 Identities = 14/82 (17%), Positives = 23/82 (28%), Gaps = 7/82 (8%) Query: 95 SACLFLALLNRGPRGYAFLLAGYTTAFIGFPAVTSPESIFDTVVARSEEIILGTVMAVLF 154 S L +AL L+ Y + E + ++ + F Sbjct: 31 STALIVALS-----AMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNV--LLEF 83 Query: 155 ASLLFPASVKPMLTARIGNWMQ 176 L FP L A + +Q Sbjct: 84 FYLCFPLLTVAALMAIASHVVQ 105
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.6 bits (77), Expect = 0.002 Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 14/86 (16%) Query: 69 AIFA-MTFLMRPIGAWYFGRFADRYGRRLALTISVSVMALCSFVIAITPTVATIGIAAPI 127 A++A M F P+ G +DR+GRR L +S++ A+ ++A P + Sbjct: 50 ALYALMQFACAPVL----GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLW-------- 97 Query: 128 ILLVARLLQGFATGGEYGTSATYMSE 153 +L + R++ G TG + Y+++ Sbjct: 98 VLYIGRIVAGI-TGATGAVAGAYIAD 122
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.3 bits (68), Expect = 0.010 Identities = 15/79 (18%), Positives = 24/79 (30%) Query: 155 EPVPSPTPVPPTPTPVQPPPAASPVQSTLVQQAKHPVPPQGDTAQGSLAERRQPRRQQRP 214 P P P P P + P P + + QP+R +P Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKP 116 Query: 215 TPPQPPAPPAASAQRRPDT 233 +P +P +A R + Sbjct: 117 VESRPASPFENTAPARLTS 135
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 27.7 bits (61), Expect = 0.028 Identities = 19/82 (23%), Positives = 30/82 (36%), Gaps = 8/82 (9%) Query: 89 ARALVEQWMDWQATELNTAWRYAFMASVRGSAAH--------TDAQAIAASVEQWNRHMA 140 AR L Q A + N ++S++ A H D+ AI + R M Sbjct: 25 ARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAIDEITARIEREMG 84 Query: 141 ILDAQLQRGGPFVLGACFTLAD 162 +D + G G +L+D Sbjct: 85 PIDILVNVAGVLRPGLIHSLSD 106
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 36.4 bits (84), Expect = 1e-04 Identities = 31/143 (21%), Positives = 56/143 (39%), Gaps = 28/143 (19%) Query: 79 ANAAALLILGTLAGSV-YPRATVMALPLLWLGSGLGAWLLGEPGSRH-------LGASGV 130 + L L L S P + ++ +PL +G L A L + + Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 131 THGLMFLVFVLGLLR----------------RDRPAIATSMIAFLFYGGMLMTILPHEAG 174 + ++ + F L+ R RP + TS +AF+ G+L + + AG Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTS-LAFIL--GVLPLAISNGAG 995 Query: 175 VSWQSHLGGAV-AGLIAALLLRL 196 Q+ +G V G+++A LL + Sbjct: 996 SGAQNAVGIGVMGGMVSATLLAI 1018
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 31.1 bits (70), Expect = 0.011 Identities = 19/94 (20%), Positives = 36/94 (38%), Gaps = 7/94 (7%) Query: 800 KRYVDAAEQF-------AEALKLRPDFALAANNLGFVYYRQGRFAESARSLENTLKIDPS 852 + Y A E F A ++ D +L F Y+ G++ ++ + + +D Sbjct: 9 QEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHY 68 Query: 853 RAVAYLNLGDAYAKAGDRDKARKAYSTYLELQPQ 886 + +L LG G D A +YS + + Sbjct: 69 DSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIK 102
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 458 bits (1180), Expect = e-158 Identities = 209/572 (36%), Positives = 302/572 (52%), Gaps = 42/572 (7%) Query: 1 MNQTRVFLIFAWLMVAALLWMEWGKDKAAANAPVVAATQSVPAARDLDAATPSAANVPAA 60 M+ R L+ A L V+ ++W W +DK P A Q+ T +AA A Sbjct: 1 MDSQRNLLVIALLFVSFMIWQAWEQDKN----PQPQAQQTT-------QTTTTAAGSAAD 49 Query: 61 QAIPQAGAPGAVPATSTTAATPAAAGAAPVVTLTSDVLRLKLD--GRSVLDAELLQFPQT 118 Q +P A+G ++++ +DVL L ++ G V A L +P+ Sbjct: 50 QGVP-------------------ASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKE 90 Query: 119 KDGTAPVSLLTEDPAHPYNATSGWASEHSPVPGVGGFRA--EQPGTTFDMAKGQNTLVVP 176 + T P LL P Y A SG P G R + +A+GQN L VP Sbjct: 91 LNSTQPFQLLETSPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVP 150 Query: 177 FVWNGPDGVSIRRTFTLERGRYAISIKDEVINKSGAPWNGYVFRKLSR---VPTILSRGM 233 + G + +TF L+RG YA+++ V N P F +L + +P L G Sbjct: 151 MTYTDAAGNTFTKTFVLKRGDYAVNVNYNVQNAGEKPLEISSFGQLKQSITLPPHLDTGS 210 Query: 234 TNPDSFSFNGATWYSPQEGYERRAFKDYMDDGGLNRQITGGWVALLQHHFFTAWIPQKDQ 293 +N +F GA + +P E YE+ F D+ LN GGWVA+LQ +F TAWIP D Sbjct: 211 SNFALHTFRGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDG 270 Query: 294 ASLYVLAQDGPRD-VAELRGPAFTVAPGQTASTEARLWVGPKLVSLIAKEDVKGLDRVVD 352 + + A G + V PGQT + + LWVGP++ + LD VD Sbjct: 271 TNNFYTANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKM-AAVAPHLDLTVD 329 Query: 353 YSRFSIMAIIGQGLFWVLSHLHSFLHNWGWAIIGLVVLLRLALYPLSAAQYKSGAKMRRF 412 Y I Q LF +L +HSF+ NWG++II + ++R +YPL+ AQY S AKMR Sbjct: 330 YGWLWF---ISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRML 386 Query: 413 QPRLAQLKERYGDDRVKYQQATMELFKKEKINPMGGCLPLLIQMPIFFALYWVLVESVEL 472 QP++ ++ER GDD+ + Q M L+K EK+NP+GGC PLLIQMPIF ALY++L+ SVEL Sbjct: 387 QPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVEL 446 Query: 473 RQAPWLGWIQDLTARDPYFILPLLNISIMWATQKLTPTPGMDPMQAKMMQFMPLVFGVMM 532 RQAP+ WI DL+A+DPY+ILP+L M+ QK++PT DPMQ K+M FMP++F V Sbjct: 447 RQAPFALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFF 506 Query: 533 AFMPAGLVLYWVVNGGLGLLIQWWMIRQHGEK 564 + P+GLVLY++V+ + ++ Q + R ++ Sbjct: 507 LWFPSGLVLYYIVSNLVTIIQQQLIYRGLEKR 538
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.5 bits (63), Expect = 0.041 Identities = 21/75 (28%), Positives = 25/75 (33%), Gaps = 5/75 (6%) Query: 213 DVIAFRDRLEEATYTARANRGTDAAADDAPPAPRPQTLPPAQAQQPATVPPPANEASTVP 272 D+ +R RL A N APPAP+P P Q PP + P Sbjct: 544 DIGTYRYRL-----AANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPP 598 Query: 273 MQPSATPPAQQGFQP 287 P P A P Sbjct: 599 QPPQRQPEAPAPQPP 613
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 31.1 bits (70), Expect = 2e-04 Identities = 10/41 (24%), Positives = 18/41 (43%) Query: 1 MGGFSIWHWLIVLVIVLLVFGTKRLTSGAKDLGSAVKEFKK 41 M L+V +I L+V G +RL K + ++ + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRS 41
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 84.3 bits (208), Expect = 8e-23 Identities = 44/138 (31%), Positives = 70/138 (50%), Gaps = 1/138 (0%) Query: 1 MFDIGVGELTLIAVVALVVLGPERLPKAARFAGLWVRRARMQWDSVKQELERELEAEELK 60 MFDIG EL L+ ++ LVVLGP+RLP A + W+R R +V+ EL +EL+ +E + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 RSLQDVQ-ASLREAEDQLRNKQQQVEQGARALHDDVSRDIDIRASATPVATPLELAHADW 119 SL+ V+ ASL +L+ ++ Q A ++ + +AS + + Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNE 120 Query: 120 SASPDVDTAAGATDAAGA 137 +A V AA T A+ Sbjct: 121 AAHEGVTPAAAQTQASSP 138
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 30.6 bits (69), Expect = 0.005 Identities = 13/70 (18%), Positives = 28/70 (40%), Gaps = 11/70 (15%) Query: 168 LLWLLLTIATF--AAMTLALFVM-------PPQVMFDRSTGGHALRESLRASLHNLP--A 216 L W++ +A A +A+ + P + DR+TG ++ L A Sbjct: 34 LAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDRNTGEASIAAKLHGDATITYDEA 93 Query: 217 MLVFFVLAFI 226 + +F+ ++ Sbjct: 94 VRKYFLATYV 103
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.1 bits (75), Expect = 0.021 Identities = 21/122 (17%), Positives = 34/122 (27%), Gaps = 15/122 (12%) Query: 2559 ALASATPTPG-SEQTPVNADASQAHRVFNAAKGKQASLTPVLTTLAEGL--GARLWGNVR 2615 + PG + V + L P L E L L G V Sbjct: 411 GAGTDPGGPGGGDDGEDPFGEWLDDEVARLRLRGRWLLKPRRAALIEALRSAPALAGCVA 470 Query: 2616 YDARQGRIEQVQQAPFQKS------------VASIKDKIRRHLRAGMTAEQATQSVGDAL 2663 +D + + V+ P++K+ ++ + T EQA D Sbjct: 471 FDELREQPVAVRAFPWRKAPGPLEDADVLRLADYVETTYGTGEASAQTTEQAINVAADMN 530 Query: 2664 RY 2665 R Sbjct: 531 RV 532
>PF05860#haemagglutination activity domain. Length = 117 Score = 79.5 bits (196), Expect = 2e-19 Identities = 31/116 (26%), Positives = 53/116 (45%), Gaps = 7/116 (6%) Query: 40 VAANQLPTGGSIVGGTGTINAASGTTRVVDQTSSRMALTWSAFDIGSAATMTFNQPTTTS 99 LP +I T GT Q S + ++ F + ++ T FN PT Sbjct: 4 TPDTTLPINSNITTEGNTRIIERGT-----QAGSNLFHSFQEFSVPTSGTAFFNNPTNIQ 58 Query: 100 VVLNLVQGGNPTQIFGNLTANG--QVFLLNSNGVLLGSTANINVGGLVVSTLGTSV 153 +++ V GG+ + I G + AN +FL+N NG++ G A +++GG V + + Sbjct: 59 NIISRVTGGSVSNIDGLIRANATANLFLINPNGIIFGQNARLDIGGSFVGSTANRL 114
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 82.7 bits (204), Expect = 2e-19 Identities = 31/193 (16%), Positives = 71/193 (36%), Gaps = 40/193 (20%) Query: 110 LGSGVIIDAQKGYVLTNHHVIENADDVQVTL------------GDGRTVKAEFIGSDADT 157 + SGV++ K +LTN HV++ L +G + + Sbjct: 103 IASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG 160 Query: 158 DIALIRIKAD--------NLTDIKLADSNALRVGDFVVAIGNPFG---FTQTVTSGIVSA 206 D+A+++ + + ++++ +V + G P T + G ++ Sbjct: 161 DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMWESKGKITY 220 Query: 207 VGRSGIRGLGYQNFIQTDASINPGNSGGALVNLQGQLVGINTASFNPQGSMAGNIGLGLA 266 + +Q D S GNSG + N + +++GI+ + N + + Sbjct: 221 L---------KGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWGGVPNE----FNGAVFIN 267 Query: 267 --IPSNLARNVVE 277 + + L +N+ + Sbjct: 268 ENVRNFLKQNIED 280
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.018 Identities = 31/168 (18%), Positives = 66/168 (39%), Gaps = 34/168 (20%) Query: 197 TLDAKDAALRQLLETARRSNRLAEQLLDLARLDAGISSAAYHQVEMGELISHVLDEFSVQ 256 L+ A + + AR + L +L R S+A QV + + ++ V + Sbjct: 178 ALNNIRALILEDPTKARE---MLTSLSELMRYSLRYSNA--RQVSLADELTVVDSYLQLA 232 Query: 257 ANTR---QMQLQVEASPCLVRCDVDAVGILIRNLVDNAIRYG----RLHGKVEVSCGYCL 309 + + ++Q + + +P ++ V +L++ LV+N I++G GK+ + Sbjct: 233 -SIQFEDRLQFENQINPAIMDVQVPP--MLVQTLVENGIKHGIAQLPQGGKILLK----G 285 Query: 310 RADVLHPFLQVSDDGPGVPESAQAAIFERFYRVPGSAVQGSGIGLSLV 357 D L+V + G ++ + + +G GL V Sbjct: 286 TKDNGTVTLEVENTGSLALKNTK---------------ESTGTGLQNV 318
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 2e-21 Identities = 25/155 (16%), Positives = 60/155 (38%), Gaps = 5/155 (3%) Query: 2 HLLLVEDDTMLANAICDGVRQQSWTIDHVGHANAAKTVLVDHRYSAVLLDIGLPGESGLS 61 +L+ +DD + + + + + + +A + V+ D+ +P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VIRFMRSHYDATPVIALTARGQLTDRIRGLDAGADDYLVKPFQFDELMARLRAVTRRSQG 121 ++ ++ PV+ ++A+ I+ + GA DYL KPF EL+ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 RVVPLLSHGD-----VCMDPSSRKVTKDGKWVALS 151 R L V + +++ + + + Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQT 159
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 39.4 bits (92), Expect = 1e-05 Identities = 15/27 (55%), Positives = 18/27 (66%) Query: 1 MHLLITGGTGFIGQALCPALLQAGHQV 27 M L+TG GFIG + LL+AGHQV Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQV 27
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 1e-18 Identities = 30/123 (24%), Positives = 59/123 (47%), Gaps = 1/123 (0%) Query: 8 GHVLIVEDEPRLAAVLGEYLHAAGYSHDWIADGAQALGAFRAQQPDLVLLDLMLPNRGGL 67 +L+ +D+ + VL + L AGY ++ A A DLV+ D+++P+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 68 DICRDLRNESA-VPVIMVTARVEEIDRLLGLEIGADDYICKPFSPREVVARVQAVLRRHR 126 D+ ++ +PV++++A+ + + E GA DY+ KPF E++ + L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 127 HDP 129 P Sbjct: 124 RRP 126
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 3e-04 Identities = 38/228 (16%), Positives = 83/228 (36%), Gaps = 45/228 (19%) Query: 246 HELRTPLAVLRAELEALQDGIRPM----TPNSLGSL-HQQVGQLGKLIEDLYDV---SLT 297 + + A+L AL+ I P N++ +L + + +++ L ++ SL Sbjct: 150 DQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLR 209 Query: 298 DVGALAYRRAPVDLAVILATV---LDGLRARFAAAQLQVQAQIDAGPLQVDGDERRLQQL 354 A V LA L V L +F +LQ + QI+ + V + L Sbjct: 210 YSNA-----RQVSLADELTVVDSYLQLASIQFED-RLQFENQINPAIMDV----QVPPML 259 Query: 355 LGNLLENTLRY----TDAGGTVQVRCVRRGAVLEMVVEDSAPGVDADKRARLFERFYRTE 410 + L+EN +++ GG + ++ + + + VE++ + + Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTK----------- 308 Query: 411 ASRNRASGGSGLGLA-ICRNIAEAHGGSIHAE-ASALGGLRMVLRLPA 456 +G GL + + +G + + G + ++ +P Sbjct: 309 -------ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 2e-06 Identities = 22/104 (21%), Positives = 47/104 (45%), Gaps = 10/104 (9%) Query: 70 VRPQVGGIVRKRLFTEGQDVQAGQVLYEIDPASYQAAYDTAKGDLAQAEAAVLSARPKAQ 129 ++P IV++ + EG+ V+ G VL ++ +A D + ++++L AR + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-------DTLKTQSSLLQARLEQT 151 Query: 130 RYQTL---VGLDAVSKQDGDDALATLRSNEAAVVAAKASLQTAR 170 RYQ L + L+ + + D +E V+ + ++ Sbjct: 152 RYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Score = 42.5 bits (100), Expect = 2e-06 Identities = 35/207 (16%), Positives = 73/207 (35%), Gaps = 25/207 (12%) Query: 103 YQAAYDTAKGDLAQAEAAVLSARPKAQRYQTLVGLDAVSKQDGDDALATLRSNEAAVVAA 162 + Y A +L ++ + + + L ++ + L LR + Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN--EILDKLRQTTDNIGLL 314 Query: 163 KASLQTARINLDYTRITAPVSGRIGT-SSYTSGALVSAGQSEVLATINQLDPIYVDVTQS 221 L + I APVS ++ +T G +V+ ++ ++ + + D + V Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET-LMVIVPEDDTLEVTALVQ 373 Query: 222 SAQLLQLRRQLDAGQLKAVDGKAEVTLQLEDGSTYAH-SGTLEVV--DAAVDTATGTV-- 276 + + + GQ A + ++ + Y + G ++ + DA D G V Sbjct: 374 NKDIGFIN----VGQ------NAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFN 423 Query: 277 KLRAVV------PNPERLLLPGMYVTA 297 + ++ N L GM VTA Sbjct: 424 VIISIEENCLSTGNKNIPLSSGMAVTA 450
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1153 bits (2983), Expect = 0.0 Identities = 587/1040 (56%), Positives = 768/1040 (73%), Gaps = 13/1040 (1%) Query: 1 MARFFIDRPIFAWVIAIVITLAGALSILSLPLEQYPNIAPPTINVSATYTGASAQTVQNS 60 MA FFI RPIFAWV+AI++ +AGAL+IL LP+ QYP IAPP ++VSA Y GA AQTVQ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQILEQQMTGLDHLLYMSSSSSSAGTASITLTFESGTDPDTAQVQVQNKVSQGEAMLPE 120 VTQ++EQ M G+D+L+YMSS+S SAG+ +ITLTF+SGTDPD AQVQVQNK+ +LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVQSNGVTVTKSTGSSMFMVLAFTSEDGSMDSTDIGDYMVSTLQDPISRLNGVGGVNVFG 180 VQ G++V KS SS MV F S++ DI DY+ S ++D +SRLNGVG V +FG Sbjct: 121 EVQQQGISVEKS-SSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 181 SEYAMRVWLDPEKLRTYSLMPADVSNAISAQNADVSSGALGALPAVQGQQLNATVTSRSK 240 ++YAMR+WLD + L Y L P DV N + QN +++G LG PA+ GQQLNA++ ++++ Sbjct: 180 AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LKTPAQFEAIVLKSQPGGATVYLRDVARVELGSKSYASSSKYNGKSASGMGLELATGANA 300 K P +F + L+ G+ V L+DVARVELG ++Y ++ NGK A+G+G++LATGANA Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 301 LDAAKAVEAKLEQLKPYFPTGLTYEVAYDTTPFVRISIEEVVKTLLEAIVLVVLVMYLFL 360 LD AKA++AKL +L+P+FP G+ YDTTPFV++SI EVVKTL EAI+LV LVMYLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 361 QNWRATLVPVIAVPVVLLGTFGVLALLGYSINTLTMFAMVLAIGLLVDDAIVVVENVERL 420 QN RATL+P IAVPVVLLGTF +LA GYSINTLTMF MVLAIGLLVDDAIVVVENVER+ Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 421 MSEQGMSPRQATYTSMGQISGALVGIALVLTAVFLPMAFFGGATGEIYRQFSVTIAAAML 480 M E + P++AT SM QI GALVGIA+VL+AVF+PMAFFGG+TG IYRQFS+TI +AM Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 481 LSLLVALTLSPALCASLLRPIAHGQQVSRKGVLGRFFGWFNVRFDRGADGYGRGVGKLIG 540 LS+LVAL L+PALCA+LL+P++ ++ G FFGWFN FD + Y VGK++G Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGG----FFGWFNTTFDHSVNHYTNSVGKILG 535 Query: 541 HRKLGGLVYLALLVVMALLFWRLPSSFLPDEDQGMLMVMFTTPAGATQQRTQQSIDQATS 600 L+Y ++ M +LF RLPSSFLP+EDQG+ + M PAGATQ+RTQ+ +DQ T Sbjct: 536 STGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTD 595 Query: 601 FILK--QPEVAGMMTISGFSFAGSSQNSGMGFIKLKDWAQRDAP---AQEIANRITGAMM 655 + LK + V + T++GFSF+G +QN+GM F+ LK W +R+ A+ + +R + Sbjct: 596 YYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKME-L 654 Query: 656 GTLPDAQVFALSPPAINGLGSSSGFTLELQDVAGKGHDALVAARQQLLQLAS-ADKDLTA 714 G + D V + PAI LG+++GF EL D AG GHDAL AR QLL +A+ L + Sbjct: 655 GKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVS 714 Query: 715 VRFNGLEDAPTYRVQIDDAKAGALGLDASDINTTLATVMGGSYVNDFLNNNRVKRVYVQG 774 VR NGLED +++++D KA ALG+ SDIN T++T +GG+YVNDF++ RVK++YVQ Sbjct: 715 VRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQA 774 Query: 775 EARARMLPADIGRWYVRNSSSEMVPFSAFSSSAWAYAPQVLSRFNGVESMEITGSAATGI 834 +A+ RMLP D+ + YVR+++ EMVPFSAF++S W Y L R+NG+ SMEI G AA G Sbjct: 775 DAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGT 834 Query: 835 SSGEAMNGIAALVGKLGKDVSYAWSGMSYQEQAAGAQTWMLYAVSLVFVFLCLAALYESW 894 SSG+AM + L KL + Y W+GMSYQE+ +G Q L A+S V VFLCLAALYESW Sbjct: 835 SSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESW 894 Query: 895 SIPISVMLAVPVGIVGALLATWLRGLSNDIYFQVGLLATMGLAAKNGILIVEFAKELEEK 954 SIP+SVML VP+GIVG LLA L ND+YF VGLL T+GL+AKN ILIVEFAK+L EK Sbjct: 895 SIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEK 954 Query: 955 -GQPLIEATLHAARMRLRPIVMTSLAFLLGVLPMVVSSGAGSGGRHSLGTGVLGGTLVST 1013 G+ ++EATL A RMRLRPI+MTSLAF+LGVLP+ +S+GAGSG ++++G GV+GG + +T Sbjct: 955 EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSAT 1014 Query: 1014 LLGIFFVPLFYVMVRSVFPG 1033 LL IFFVP+F+V++R F G Sbjct: 1015 LLAIFFVPVFFVVIRRCFKG 1034
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 5e-04 Identities = 31/177 (17%), Positives = 56/177 (31%), Gaps = 22/177 (12%) Query: 6 PLRVVAVSGGMQRPSKAVALAEHLLELIADQVPCERHLVEIGALAPHFAGALWRTQVPGT 65 PLR R L H ++ + +++ + PG Sbjct: 309 PLR--------DRAEDIPDLVRHFVQQAE------KEGLDVKRFDQEALELMKAHPWPGN 354 Query: 66 VEQALCLVEQADVLVVATPVYRGSFTGLFKHFFDFIDQDALIDTPVLLAATGGSDRHALV 125 V + LV + L + R + + + + AA GS + Sbjct: 355 VRELENLVRRLTALYPQDVITR-------EIIENELRSEIPDSPIEKAAARSGSLSISQA 407 Query: 126 IDHQLRPLFSFFQARTLPLGVYATDRDFLDYRVHNDALAERARLAVQRALPLIELTR 182 ++ +R F+ F P G+Y ++Y + AL R +A L+ L R Sbjct: 408 VEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAAL-TATRGNQIKAADLLGLNR 463
>INTIMIN#Intimin signature. Length = 939 Score = 28.5 bits (63), Expect = 0.044 Identities = 21/91 (23%), Positives = 36/91 (39%), Gaps = 2/91 (2%) Query: 218 TIAHTGTSGVLLGVAVVVITGLPLLLADRWIGGGNGTAGVAASSTAGAAVATPALIAGMA 277 T+ G + + V+ +++G +L A+ G+G A V S V A A M Sbjct: 583 TVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEM- 641 Query: 278 PQFAPAAPAATALVASAVIVTSLLVPLLTAL 308 A A A + + +T + TA+ Sbjct: 642 -TSALNANAVIFVDQTKASITEIKADKTTAV 671
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.7 bits (69), Expect = 0.010 Identities = 12/43 (27%), Positives = 15/43 (34%), Gaps = 1/43 (2%) Query: 63 SAMPAVPAQPLPPA-PGAATPADAAIAQVAPMPAPVATPAPAK 104 P +P P P P +A + P P P P P K Sbjct: 67 QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 35.9 bits (83), Expect = 1e-04 Identities = 27/129 (20%), Positives = 44/129 (34%), Gaps = 35/129 (27%) Query: 9 LVTGASGQLGALVVEALLGHLPANRIVA---------TARDTASLAEFAKRDIAVRQADY 59 LVTGA+G +G V + LL +++V + A L A+ + D Sbjct: 4 LVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 60 ANPQSLDTAF--------------AGVGRVL-----LVSSNAVGQRVPQHRNVIEAAKRA 100 A+ + + F V L SN G N++E + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTG-----FLNILEGCRHN 116 Query: 101 GVELLAYTS 109 ++ L Y S Sbjct: 117 KIQHLLYAS 125
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 25.8 bits (56), Expect = 0.023 Identities = 23/73 (31%), Positives = 31/73 (42%), Gaps = 17/73 (23%) Query: 16 TTDGRTIRLEIYRGPDTGWTLEAVDEFNNSTVWDDLFATDQAAL------------DEAL 63 +DG ++ + YR G +LEA F T D F QA L L Sbjct: 749 GSDGYAVKGK-YRTHGVGASLEAGRRF---THADGWFLEPQAELAVFRAGGGAYRAANGL 804 Query: 64 RTIRDEGIDSLIG 76 R +RDEG S++G Sbjct: 805 R-VRDEGGSSVLG 816
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 82.3 bits (203), Expect = 4e-20 Identities = 45/188 (23%), Positives = 81/188 (43%), Gaps = 11/188 (5%) Query: 3 ALRYLVVLLVALLLSACSQQ---LYSGLTENDANDMLEVLLHAGVDASKVTPDDGKTWAI 59 A V ++VA++L A + L+S L++ D ++ L + + G AI Sbjct: 30 AGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQMNIPY-RFANGSG---AI 85 Query: 60 NAPHDQVSYSLEVLRAHGLPHERHANLG-EMFKKDGLISTPTEERVRFIYGVSQQLSQTL 118 P D+V L GLP + +G E+ ++ + E+V + + +L++T+ Sbjct: 86 EVPADKVHELRLRLAQQGLP--KGGAVGFELLDQEKFGISQFSEQVNYQRALEGELARTI 143 Query: 119 SNIDGVISADVEIVLPNNDPLSTSVKPSSAAVFIKFRVGSDLT-SLVPNIKTLVMHSVEG 177 + V SA V + +P K SA+V + G L + + LV +V G Sbjct: 144 ETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAG 203 Query: 178 LTYENVSV 185 L NV++ Sbjct: 204 LPPGNVTL 211
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 28.2 bits (62), Expect = 0.025 Identities = 57/245 (23%), Positives = 87/245 (35%), Gaps = 48/245 (19%) Query: 4 WLRSTPDAIGLDCDVIPREALASVLALDAATAEVHARCEQALSQAQTRAQTLIDEAQQQA 63 W TPD D E + V + E EQ L+Q Q +A +Q Sbjct: 7 WKTWTPD----DLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAH------EQGY 56 Query: 64 EAILHDARQKAERSARLGYATGLRRQLDEWNESGLRHAFAADTAAQRARERLAEIVARTC 123 +A + + RQ+ + GY GL + L E GL A + ++L T Sbjct: 57 QAGIAEGRQQGHKQ---GYQEGLAQGL----EQGLAEAKSQQAPIHARMQQLVSEFQTTL 109 Query: 124 EHI------------------ILGHDPA----ALYARAAQALEGALDEAKALRVSVHPDA 161 + + ++G P AL + Q L+ + ++ VHPD Sbjct: 110 DALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDD 169 Query: 162 VDAARRAFDATATEAGWTLQVELCGDADLAVGACVCEWDTGVFETDLRDQLRSLRRVIRR 221 + AT + GW L+ GD L G C D G + + + + L R Sbjct: 170 LQRVDDMLGATLSLHGWRLR----GDPTLHPGGCKVSADEGDLDASVATRWQELCR---- 221 Query: 222 VLAAP 226 LAAP Sbjct: 222 -LAAP 225
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.9 bits (64), Expect = 0.011 Identities = 13/75 (17%), Positives = 24/75 (32%), Gaps = 13/75 (17%) Query: 93 AEQAQTAASQSLQSARDELASVQQALSKLQAQAQV-------------YADKAASARRAR 139 +E +T A S Q ++ + Q A +V + A S + Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETK 1093 Query: 140 QAQREAAEEEDAIEA 154 + Q +E +E Sbjct: 1094 ETQTTETKETATVEK 1108
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 177 bits (451), Expect = 5e-57 Identities = 51/240 (21%), Positives = 105/240 (43%), Gaps = 3/240 (1%) Query: 8 LLAISSQGVSLLTLLALCGVRVFVMFIVLPATAQDSLPGIARNGVIYVLSSFIAYGQPAD 67 L S Q +S L L +RV + P ++ S+P + G+ +++ IA PA+ Sbjct: 2 LQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPAN 61 Query: 68 ALAKIQTVGLVGVVFKEAFIGLLIGFAASTVFWIAESVGLLIDDLAGYNNVQMTNPLSGQ 127 + L + ++ IG+ +GF F + G +I G + +P S Sbjct: 62 DVPVFSFFAL-WLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 128 QSTPVSTVLLQLAIVSFYALGGMLMLLGALFESFRWWPLTQLGPNMGAVAESFVIQQSDS 187 ++ ++ LA++ F G L L+ L ++F P+ + + A + + Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGG--EPLNSNAFLALTKAGSL 178 Query: 188 MMAAVVKLSAPVMLVLVLVDLAIGLVARAADKLEPSNLSQPIRGVLALLLLALLTSVFIA 247 + + L+ P++ +L+ ++LA+GL+ R A +L + P+ + + L+A L + Sbjct: 179 IFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAP 238
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 334 bits (857), Expect = e-109 Identities = 100/288 (34%), Positives = 153/288 (53%), Gaps = 13/288 (4%) Query: 320 DAGGGAELASDAPVIEADPRTNTILIRDRPERMQSYGTLIQQLDNRPKLLQIDATIIEIR 379 A AS +EADP N I++RD PERM Y LI LD +++ +I++I Sbjct: 233 RIPQAATRASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDIN 292 Query: 380 DGAMQDLGVDWRFHSQHTDIQTGNGSGGQLGFNGALSGAATDGATTPAGGTLTAVLGDAG 439 + +LGVDWR I+TGN + G S A++GA G+L G Sbjct: 293 ADQLTELGVDWR-----VGIRTGNNHQVVIKTTGDQSNIASNGAL----GSLVDARGL-- 341 Query: 440 RYLMTRVSALETTNKAKIVSSPQVATLDNVEAVMDHKQQAFVRVSGYASADLYNLSAGVS 499 YL+ RV+ LE A++VS P + T +N +AV+DH + +V+V+G A+L ++ G Sbjct: 342 DYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSETYYVKVTGKEVAELKGITYGTM 401 Query: 500 LRVLPSVVPGSPNGQMRLDVRIEDGQLGSNT--VDGIPVITSSEITTQAFVNEGQSLLIA 557 LR+ P V+ ++ L++ IEDG N+ ++GIP I+ + + T A V GQSL+I Sbjct: 402 LRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEGIPTISRTVVDTVARVGHGQSLIIG 461 Query: 558 GYAYDADETDLNAVPGLSKIPLLGNLFKHRQKSGSRMQRLFLLTPHVV 605 G D L+ VP L IP +G LF+ + + R RLF++ P ++ Sbjct: 462 GIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRII 509 Score = 251 bits (643), Expect = 1e-77 Identities = 71/230 (30%), Positives = 115/230 (50%), Gaps = 6/230 (2%) Query: 15 LAAVLMLSLLPVLSPHADAAQVPWHSRTFKYVADNKDLKEVLRDLSASQSIATWISPEVT 74 VL +LL +LS ++ A ++ W + YVA + L+++L D A+ +S ++ Sbjct: 9 FKRVLTGTLL-LLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIN 67 Query: 75 GTLSGKFE-TSPQKFLDDLAATYGFVWYYDGAVLRIWGANESKSATLSLGTASTKSLRDA 133 +SG+FE +PQ FL +A+ Y VWYYDG VL I+ +E S + L + L+ A Sbjct: 68 DKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQA 127 Query: 134 LARMRLDDPRFPVRYDETAHVAVVSGPPGYVDTVSAIAKQVEQGARQR----DATEVQVF 189 L R + +PRF R D + + VSGPP Y++ V A +EQ + R A +++F Sbjct: 128 LQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIF 187 Query: 190 QLHYAQAADHTTRIGGQDVQIPGMASLLRSMYGARGAPVAAIPGPGANFG 239 L YA A+D T +V PG+A++L+ + + Sbjct: 188 PLKYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQA 237
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 117 bits (294), Expect = 6e-34 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 9/261 (3%) Query: 1 MSNTALRPQRVLIAGGSRGIGLAIAEAFVRHGAQVSICARNAAGLAQAADALAAQGAPVH 60 M+ + + I G ++GIG A+A GA ++ N L + +L A+ Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 61 TLPCDLADATQIDAYVHAAAQALDGLDVVINNAS----GFGHGNDDASWQAGLEIDLMAA 116 P D+ D+ ID + + +D+++N A G H D W+A ++ Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 117 VRCNRAALPYLRRSDAAVILNISSINAQRPTPRAIAYSTAKAALNYYTTTLAAELARERI 176 +R+ Y+ + I+ + S A P AY+++KAA +T L ELA I Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 177 RVNAIAPGSIE--FPDGLWDTRSREQPELY---ARIRDSIPFGGFGQVQHVADAALFLAS 231 R N ++PGS E LW + + + + IP + +ADA LFL S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 232 PQASWITGQVLAVDGGQSLGV 252 QA IT L VDGG +LGV Sbjct: 241 GQAGHITMHNLCVDGGATLGV 261
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.4 bits (146), Expect = 2e-13 Identities = 27/194 (13%), Positives = 55/194 (28%), Gaps = 6/194 (3%) Query: 18 DVRDQIVVAATEHFSRYGYEKTAVSDLAKEIGFSKAYIYKFFESKQAIGEMICSHCLGEI 77 + R I+ A FS+ G T++ ++AK G ++ IY F+ K + I I Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 78 -EADVLAAVSAASSPPEKLRSLFRAIIEASLRLYSRERKLYEIATSA-ATERWPPVI--- 132 E ++ P LR + ++E+++ R + I V Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 133 -AYEGHIQALLQDILVQGRQNGDFERKTPLDELTQAIYLVMRPYINPVLLQHSLEHAGDV 191 ++ L + + + + L Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 192 PLLLSGLVLRSLSP 205 ++L Sbjct: 191 ARDYVAILLEMYLL 204
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 415 bits (1067), Expect = e-130 Identities = 223/1053 (21%), Positives = 425/1053 (40%), Gaps = 75/1053 (7%) Query: 8 LSALAVRERAVTLFLIVLISLAGLVAFLKLGRAEDPAFTVKVMTIVTAWPGATPQEMQDQ 67 ++ +R L +++ +AG +A L+L A+ P +++ +PGA Q +QD Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 68 VAEKLEKRLQELR--WYDRSETYTRPGLAFTTLTLLDSTPP----SQVQEQFYQARKKVG 121 V + +E+ + + Y S + G TLT T P QVQ + A Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTS-DSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPL-- 117 Query: 122 DEVANLPAGVIGPMVNDEYADVTFAL---FALKAKGEPQRLLARDAE-MLRQRMLHVPGV 177 LP V ++ E + ++ + F G Q ++ ++ + + GV Sbjct: 118 -----LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGV 172 Query: 178 KKVNIIGEQPERIFVEFSHARLATLGVSAQDVFAALNAQNAVNAAGSVETRGP------Q 231 V + G Q + + L ++ DV L QN AAG + Sbjct: 173 GDVQLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLN 231 Query: 232 IFIRLDGALDSLQKIRDTPLVVQ--GRTLKLSDTATVKRGYEDPSTFLIRSGGEPALLLG 289 I + ++ L V G ++L D A V+ G E+ + R G+PA LG Sbjct: 232 ASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIA-RINGKPAAGLG 290 Query: 290 IIMRDGWNGLDLGKSLDAEVGAINAELPLGMRLSKVTDQAVNIDASVGEFMTKFFVALLV 349 I + G N LD K++ A++ + P GM++ D + S+ E + F A+++ Sbjct: 291 IKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIML 350 Query: 350 VMLVCFVSMG-WRVGIVVAAAVPLTLAAVFVVMLATGKNFDRITLGSLILALGLLVDDAI 408 V LV ++ + R ++ AVP+ L F ++ A G + + +T+ ++LA+GLLVDDAI Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAI 410 Query: 409 IAIEMMV-VKMEEGYSRVAASAYAWSHTAAPMLSGTLVTAVGFMPNGFAASTAGEYTSNM 467 + +E + V ME+ A+ + S ++ +V + F+P F + G Sbjct: 411 VVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQF 470 Query: 468 FWIVGIALIMSWVVAVVFTPYLGVKML--------PEMKKIAGGHAAMYDTPHYNRFRNV 519 + A+ +S +VA++ TP L +L G +D N + N Sbjct: 471 SITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFD-HSVNHYTNS 529 Query: 520 LGHVIARKWLVAGAVVGLFTLAMGGMGI----VKKQFFPISDRPEVLVEVQLPYGTSINQ 575 +G ++ + + GM + + F P D+ L +QLP G + + Sbjct: 530 VGKILGSTGRYLLIYALI----VAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQER 585 Query: 576 TSAATAKVEAWLAKRDEARIVTAYIGQGAPRFFLAMGPELPDPSFAKIVV-----RTDDQ 630 T +V + K ++A + + + G + + + A + + R D+ Sbjct: 586 TQKVLDQVTDYYLKNEKANVESVFTVNG-----FSFSGQAQNAGMAFVSLKPWEERNGDE 640 Query: 631 HQRDILKLRLRQAVAEGLASEARVRV----TQLTFGPYSRFPVA-YRVSGPDPQVVRGIA 685 + + + R + + + + V + G + F +G + Sbjct: 641 NSAEAVIHRAKMELGK--IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQAR 698 Query: 686 GKV-EQVMRGSPMLRTVDTDWGVRTPTLYFSLDQDRLQAVGLSSTAVAQQLQFLLSGVPI 744 ++ + L +V + T +DQ++ QA+G+S + + Q + L G + Sbjct: 699 NQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYV 758 Query: 745 TQVREDIRSVQVVARSAGTTRLDPARIADFTLAGGNGQRVPLAQVGKVDIRMEEPIMRRR 804 + R ++ ++ R+ P + + NG+ VP + P + R Sbjct: 759 NDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERY 818 Query: 805 DRVPTITVGGDVDDQLQPPDVSAAISKQLQPLIATLPSGYQITQAGAIEESGKATTAMLP 864 + +P++ + G+ P S ++ L + LP+G G + + Sbjct: 819 NGLPSMEIQGEA----APGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPA 874 Query: 865 LFPIMLAATLLIIILQLRSISAMVMVFLTSPLGLIGVVPTLLLFQQPFGINALVGLIALS 924 L I L + S S V V L PLG++GV+ LF Q + +VGL+ Sbjct: 875 LVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTI 934 Query: 925 GILMRNTLILIGQIHH-NQAEGLDPFHALVEATVQRARPVILTALAAILAFIPLTHSVFW 983 G+ +N ++++ + EG A + A R RP+++T+LA IL +PL S Sbjct: 935 GLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA 994 Query: 984 GT-----LAYTLIGGTLAGTVLTLVFLPAMYSI 1011 G+ + ++GG ++ T+L + F+P + + Sbjct: 995 GSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027 Score = 80.7 bits (199), Expect = 2e-17 Identities = 56/326 (17%), Positives = 118/326 (36%), Gaps = 20/326 (6%) Query: 714 FSLDQDRLQAVGLS----STAVAQQLQFLLSGVPITQVREDIRSVQVVARSAGTTRLDPA 769 LD D L L+ + Q + +G + + + + +P Sbjct: 186 IWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK-NPE 244 Query: 770 RIADFTL-AGGNGQRVPLAQVGKVDIRMEE-PIMRRRDRVPTITVGGDVDDQLQPPDVSA 827 TL +G V L V +V++ E ++ R + P +G + D + Sbjct: 245 EFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAK 304 Query: 828 AISKQLQPLIATLPSGYQIT----QAGAIEESGKATTAMLPLFPIMLAATLLIIILQLRS 883 AI +L L P G ++ ++ S L IML L++ L L++ Sbjct: 305 AIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTL-FEAIMLVF--LVMYLFLQN 361 Query: 884 ISAMVMVFLTSPLGLIGVVPTLLLFQQPFGINALVGLIALSGILMRNTLILIGQIH-HNQ 942 + A ++ + P+ L+G L F + G++ G+L+ + ++++ + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 943 AEGLDPFHALVEATVQRARPVILTALAAILAFIPL-----THSVFWGTLAYTLIGGTLAG 997 + L P A ++ Q ++ A+ FIP+ + + + T++ Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 998 TVLTLVFLPAMYSIWFKIRPDPDKGR 1023 ++ L+ PA+ + K Sbjct: 482 VLVALILTPALCATLLKPVSAEHHEN 507
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (253), Expect = 6e-28 Identities = 56/185 (30%), Positives = 82/185 (44%), Gaps = 8/185 (4%) Query: 6 VVLITGVSSGIGRAAAEHFARTGCIVYGSVRHLAGATPLTAVELVE--------MDIRDA 57 + ITG + GIG A A A G + + + + E D+RD+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 58 ASVQRAVDGIIARAGRIDVLVNNAGANLVGAIEETSVDEAAALFDINVLGILRTVQAVLP 117 A++ I G ID+LVN AG G I S +E A F +N G+ ++V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 118 HMRARGQGRIVNVSSVLGFLPAPYMGVYAASKHAVEGLSETLDHELRQFGIRVTLVEPAY 177 +M R G IV V S +P M YA+SK A ++ L EL ++ IR +V P Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 178 TKTSL 182 T+T + Sbjct: 190 TETDM 194
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.023 Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 252 LLVFVASRHSADKVAEKLSKTGIAALPLHGELSQGRRERTLRAFKQADVQ--VLVATDLA 309 +LV S ++ V+ +L+K GI H L+ QA V +AT++A Sbjct: 452 VLVGTISIEKSELVSNELTKAGIK----HNVLNAKFHANEAAIVAQAGYPAAVTIATNMA 507 Query: 310 GRGIDI 315 GRG DI Sbjct: 508 GRGTDI 513
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 28.3 bits (63), Expect = 0.008 Identities = 18/103 (17%), Positives = 38/103 (36%), Gaps = 10/103 (9%) Query: 44 EYKESIDEMKHADKLSDRILFLEGLPNF---QALGKLRI---GENPTEMFRCDLILEREA 97 E + E D +++R+L + G P + I G + ++ Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 98 VVV--LREAVAYAETVKDYVSRQLLVDILESEEEHIDWLETQL 138 + + + AE +D + L V ++E E+ + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.3 bits (141), Expect = 6e-11 Identities = 25/132 (18%), Positives = 48/132 (36%), Gaps = 5/132 (3%) Query: 498 RILLVEDNPVNLLVAQKLLAVLGFEADTATDGEAALARMESTRYDMVFMDCQMPVLDGYA 557 IL+ +D+ V + L+ G++ ++ + + D+V D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 558 ATRRWRAMETESGGRPVPIVAMTANAMAGDRERCLAAGMDDYLSKPVAREQLDACLQRWL 617 R + + +P++ M+A + G DYL KP +L + R L Sbjct: 65 LLPRIKKARPD-----LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 618 PRQALLPGPSPA 629 P Sbjct: 120 AEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 5e-14 Identities = 28/133 (21%), Positives = 56/133 (42%), Gaps = 4/133 (3%) Query: 67 RVLIVEDDRSQALFAQSVLHGAGMHAQVEMTAASVPQAIQDYHPDLILMDLHMPELDGIR 126 +L+ +DD + L AG ++ AA++ + I DL++ D+ MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 127 LTTLIRQQPGQQLLPIVFLTGDPDPERQFEVLDSGADDFLTKPIRPRHLIAAVSN--RIR 184 L I++ + LP++ ++ + + GA D+L KP LI + Sbjct: 65 LLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 185 RARQQALQQAGEQ 197 + R L+ + Sbjct: 123 KRRPSKLEDDSQD 135
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 35.4 bits (81), Expect = 2e-04 Identities = 20/79 (25%), Positives = 29/79 (36%), Gaps = 1/79 (1%) Query: 55 EAALQQAQRSQVQQRRQIEQLQQRQVNLAMSDKISRAANTEVQASLAERDEQIAALRADV 114 A Q +R R +QL+ L +KIS A+ ++ L E L A+ Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 115 AFYERLVG-STAQRKGLNA 132 E S A R+ L Sbjct: 368 QKLEEQNKISEASRQSLRR 386
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 69.3 bits (169), Expect = 9e-17 Identities = 17/120 (14%), Positives = 41/120 (34%), Gaps = 5/120 (4%) Query: 1 MRVRTEEKREAIVQAASEVFLELGFEGASMSQIAARVGGSKRTLYGYFPSKEELFVAVAN 60 + +E R+ I+ A +F + G S+ +IA G ++ +Y +F K +LF + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW- 63 Query: 61 DMSDRYFDPLLHALSQSSGPVDEAL-QRFGEDVLTFLCAPPNITSWQTIIGVSGRSAVGA 119 + + + E ++ L + + ++ + Sbjct: 64 ---ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 21/112 (18%), Positives = 37/112 (33%), Gaps = 12/112 (10%) Query: 68 EIRPQVGGIVQSRQFTEGGDVKAGQTLYQIDPAQYRASYASAQASLAKAEATLRTAQLKA 127 EI+P IV+ EG V+ G L ++ A+A K +++L A+L+ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALG-------AEADTLKTQSSLLQARLEQ 150 Query: 128 ERYKELAQIKAISQQEGDDTDAALGQAKADVAAGKASVETARINLAFARLDA 179 RY+ L E + + +L + Sbjct: 151 TRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Score = 31.3 bits (71), Expect = 0.006 Identities = 15/36 (41%), Positives = 17/36 (47%), Gaps = 1/36 (2%) Query: 67 SEIRPQVGGIVQSRQ-FTEGGDVKAGQTLYQIDPAQ 101 S IR V VQ + TEGG V +TL I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPED 363
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1218 bits (3153), Expect = 0.0 Identities = 668/1034 (64%), Positives = 808/1034 (78%), Gaps = 3/1034 (0%) Query: 1 MARFFIDRPIFAWVLAIIVMLAGILSIATLPIAQYPAIAPPAVAITANYPGASAQTLEDT 60 MA FFI RPIFAWVLAII+M+AG L+I LP+AQYP IAPPAV+++ANYPGA AQT++DT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQKMKGLDHLSYMASTSESSGAVTITLTFENGTDPDTAQVQVQNKLSLATPLLPQ 120 VTQVIEQ M G+D+L YM+STS+S+G+VTITLTF++GTDPD AQVQVQNKL LATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVTVTKSATNFLNVLAFTSEDGSMSDSDLSDYVAANVQETISRLEGVGDTTLFGS 180 EVQQQG++V KS++++L V F S++ + D+SDYVA+NV++T+SRL GVGD LFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRVWMDPNKLSNFSLTPVDVRNAIQAQNAQISAGQLGALPALANQQLNATITAQTRL 240 QYAMR+W+D + L+ + LTPVDV N ++ QN QI+AGQLG PAL QQLNA+I AQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KTAEQFENILLRTQSDGSQVRLRDVARIELGSESYNTVGRYNGKPAAGLAIKLATGANAL 300 K E+F + LR SDGS VRL+DVAR+ELG E+YN + R NGKPAAGL IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTVRAIDKSLEEQEKFFPPGMKVQKPYDTTPFVRISIEQVVHTLVEAVVLVFLVMYLFLQ 360 DT +AI L E + FFP GMKV PYDTTPFV++SI +VV TL EA++LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAAFGFTINTLTMFAMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTF +LAAFG++INTLTMF MVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 GEEQLSPKDATRKSMDQISGALIGVALVLAAVFVPMAFFSGSTGVIYRQFSITIVSAMTL 480 E++L PK+AT KSM QI GAL+G+A+VL+AVF+PMAFF GSTG IYRQFSITIVSAM L Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVAMILTPALCATLLKPVHKGHGLATTGFFGWFNRLFDRGNTGYQGVVRHMLGKGWRY 540 SVLVA+ILTPALCATLLKPV H GFFGWFN FD Y V +LG RY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 MLAYAALLALVVFGFMKLPVGFLPDEDQGTLFVLVQLPPGATNARTSDVLKQVEHHFLVD 600 +L YA ++A +V F++LP FLP+EDQG ++QLP GAT RT VL QV ++L + Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 QKESVAGVFAVTGFSFAGSGQNVGFAFVKLRPWDERTGKGQSVTDVAAKAGAFFSGIRDA 660 +K +V VF V GFSF+G QN G AFV L+PW+ER G S V +A IRD Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 KVFAFAPPAVSELGNATGFDLMLQDRANLGHAALMQARNQLLAELSQD-KRLVAVRPNGQ 719 V F PA+ ELG ATGFD L D+A LGH AL QARNQLL +Q LV+VRPNG Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 720 EDTPEFKLEIDPHKAQAMGVSISDINDTFSSAWGSTYVNDFIDKGRVKKVMLQADAPYRM 779 EDT +FKLE+D KAQA+GVS+SDIN T S+A G TYVNDFID+GRVKK+ +QADA +RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 780 NPQDIDHWFVRNSAGTMVPFNAFATASWQSGSPRLERYNSVPSMEILGMALPGAASSGEA 839 P+D+D +VR++ G MVPF+AF T+ W GSPRLERYN +PSMEI G A PG SSG+A Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG-TSSGDA 839 Query: 840 MQIVEAAAAKLPPGIGFEWTGLSRQEKASSGQTGLLYSVSILIVFLCLAALYESWAIPFS 899 M ++E A+KLP GIG++WTG+S QE+ S Q L ++S ++VFLCLAALYESW+IP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 900 VILVVPLGVFGTLLAAMLTWKMNDVYFQVGLLTTIGLASKNAILIVEFARELHE-GGKSL 958 V+LVVPLG+ G LLAA L + NDVYF VGLLTTIGL++KNAILIVEFA++L E GK + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 959 VAAALEAARMRLRPILMTSLAFILGVVPLVLTSGAGAGAQHALGTAVIGGMVSGTVLAIF 1018 V A L A RMRLRPILMTSLAFILGV+PL +++GAG+GAQ+A+G V+GGMVS T+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1019 FVPLFFVLVCGLFQ 1032 FVP+FFV++ F+ Sbjct: 1020 FVPVFFVVIRRCFK 1033 Score = 59.1 bits (143), Expect = 8e-11 Identities = 45/338 (13%), Positives = 109/338 (32%), Gaps = 18/338 (5%) Query: 714 VRPNGQEDTPEFKLEIDPHKAQAMGVSISDINDTFSSA----WGSTYVNDFIDKGRVKKV 769 V+ G + ++ +D ++ D+ + G+ Sbjct: 175 VQLFGAQY--AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 770 MLQADAPYRMNPQDIDHWFVR-NSAGTMVPFNAFATASWQSGSPR-LERYNSVPSMEILG 827 + A ++ NP++ +R NS G++V A + + R N P+ + Sbjct: 233 SIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGI 291 Query: 828 MALPGA---ASSGEAMQIVEAAAAKLPPGIGFEWTGLSRQEKASSGQTGLLYSV--SILI 882 GA ++ + P G+ + ++ ++ +I++ Sbjct: 292 KLATGANALDTAKAIKAKLAELQPFFPQGMKVLYP-YDTTPFVQLSIHEVVKTLFEAIML 350 Query: 883 VFLCLAALYESWAIPFSVILVVPLGVFGTLLAAMLTWKMNDVYFQVGLLT-TIGLASKNA 941 VFL + ++ + VP+ + GT A + + + + + IGL +A Sbjct: 351 VFLVMYLFLQNMRATLIPTIAVPVVLLGTF-AILAAFGYSINTLTMFGMVLAIGLLVDDA 409 Query: 942 ILIVE-FARELHEGGKSLVAAALEAARMRLRPILMTSLAFILGVVPLVLTSGAGAGAQHA 1000 I++VE R + E A ++ ++ ++ +P+ G+ Sbjct: 410 IVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ 469 Query: 1001 LGTAVIGGMVSGTVLAIFFVPLFFVLVCGLFQRRPQPA 1038 ++ M ++A+ P + Sbjct: 470 FSITIVSAMALSVLVALILTPALCATLLKPVSAEHHEN 507
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.4 bits (79), Expect = 9e-04 Identities = 31/204 (15%), Positives = 58/204 (28%), Gaps = 28/204 (13%) Query: 229 VASQLTLRQAQTTVETARVDVERYTA-QVAQDRNALVLLVGTQVPVELLPHALPDNASVE 287 + ++ + Q+++ AR++ RY + + N L L P +V Sbjct: 130 LGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP---------DEPYFQNVS 180 Query: 288 GNVLASVPAGLPSQLLQRRPDILEAERNLRAANANIGAARAAFFPSISLTASTGSSSSSL 347 + + + + Q + + E NL A A +L+ S Sbjct: 181 EEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDF 240 Query: 348 SRLFDAGTRAWSFVPTLTLPIFNAGRNRANLDMAKANRDIEVARYEKSIQSA-------- 399 S L + + A ++ +E E I SA Sbjct: 241 SSLLHKQ-----AIAKHAVLEQENKYVEAVNELRVYKSQLEQI--ESEILSAKEEYQLVT 293 Query: 400 ---FREVSDALAQRDTLGRQLQAQ 420 E+ D L Q L + Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLE 317
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 8e-16 Identities = 44/213 (20%), Positives = 68/213 (31%), Gaps = 18/213 (8%) Query: 5 APPIARAPHDKRGAILAAARVLFQQHGFDRTSMDTIAERAMVSKATVYAHFASKEVLFRT 64 A + + R IL A LF Q G TS+ IA+ A V++ +Y HF K LF Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF-- 59 Query: 65 TLEALAQASPNRWTALLALQGPLEQRLAAVADAVLRVSASSMREDAAYGLVRPPLLPSQM 124 E + N L Q +V +L S + L+ + Sbjct: 60 -SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCE 118 Query: 125 REEMW--------TLCFERYDTMMRTLLAREVQRGALVIDNVPDASVH-FFGLMTGRPAT 175 LC E YD + + L ++ L D + + G ++G Sbjct: 119 FVGEMAVVQQAQRNLCLESYDRIEQ-TLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177 Query: 176 AAARDDAPGARSVQLDAYVSGAVALFLRAYRPD 208 + + D VA+ L Y Sbjct: 178 WLFAPQSFDLKKEARD-----YVAILLEMYLLC 205
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 30.4 bits (68), Expect = 0.003 Identities = 23/62 (37%), Positives = 24/62 (38%), Gaps = 3/62 (4%) Query: 44 NSRVRELAATPGDGRVLVVDGQGSLKHALLGDQIAANAVANGWAGVLIHG---CVRDVEI 100 N V ELA G G V +LLGD N V GWA I C DV Sbjct: 337 NFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAEAIEKNPPCKNDVIY 396 Query: 101 LA 102 LA Sbjct: 397 LA 398
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 35.2 bits (81), Expect = 4e-04 Identities = 24/144 (16%), Positives = 52/144 (36%), Gaps = 28/144 (19%) Query: 2 LMVASLATTTHAAELPAGMQQFDAQMERVRKQFDVPGIAVAIVKDGQVVLERGYGVRETG 61 L +A A+ ++ Q ++ G+ + G+ + + Sbjct: 15 LPLAVHASPQPLEQIKLSESQLSGRV----------GMIEMDLASGRTLT--AW------ 56 Query: 62 KPAPVQADTLFAIASNTKAFTAASLSILADEGKLSLDDKVI----DHLPWFRMSDPYVSG 117 +AD F + S K ++ D G L+ K+ D + + +S+ +++ Sbjct: 57 -----RADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLAD 111 Query: 118 QMRIRDLLAHRSGLS-LGAGDLLF 140 M + +L A +S A +LL Sbjct: 112 GMTVGELCAAAITMSDNSAANLLL 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.7 bits (233), Expect = 2e-24 Identities = 35/130 (26%), Positives = 64/130 (49%), Gaps = 1/130 (0%) Query: 1 MTGKKVLLVEDDSDSASILEAYLRRDGFDVAVAGDGERAIQLHRQWAPDLVLLDVMLPKL 60 MTG +L+ +DD+ ++L L R G+DV + + + DLV+ DV++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGIEVLSTIRRAG-DTPVIMVTAIGDEPEKLGALRYGADDYVVKPYSPKEVVARVHAVLR 119 + ++L I++A D PV++++A + A GA DY+ KP+ E++ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RSVAMRAPGE 129 + E Sbjct: 121 EPKRRPSKLE 130
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 2e-06 Identities = 15/134 (11%), Positives = 39/134 (29%), Gaps = 3/134 (2%) Query: 68 GRLSAVLVDVGDRVTRGQLLARLDDEPLRLREQQADANVRAALAQSGERQLQLRQQQAMF 127 + ++V G+ V +G +L +L + +++ A + Q+ R + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 128 DDGASSNATLTAARAAADAAAAQLQVARADLAMARRGTRLGELRAPFDGSVVARLQQPQA 187 + + + + + + EL A A Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL---DKKRAERLTVLA 221 Query: 188 DVAAGQTVLQVEGQ 201 + + + +VE Sbjct: 222 RINRYENLSRVEKS 235 Score = 34.0 bits (78), Expect = 0.001 Identities = 15/136 (11%), Positives = 33/136 (24%), Gaps = 9/136 (6%) Query: 95 LRLREQQADANVRAALAQSGERQLQLRQQQAMFDDGASSNATLTAARAAADAAAAQLQVA 154 + + + +S + Q L +L Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 155 RADLAMARRGTRLGELRAPFDGSVVA-RLQQPQADVAAGQTVLQVEGQGHVQLV-ATLPA 212 + +RAP V ++ V +T++ + + V A + Sbjct: 322 EERQQAS-------VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQN 374 Query: 213 TAGAGLVPGQTVHARV 228 + GQ +V Sbjct: 375 KDIGFINVGQNAIIKV 390
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 429 bits (1105), Expect = e-136 Identities = 231/1044 (22%), Positives = 426/1044 (40%), Gaps = 72/1044 (6%) Query: 13 LTLFAAAMILIGGIVAFLGFPSQEEPSVTVRDTLVSVAYPGMPSEQVENLLARPVEERLR 72 A ++++ G +A L P + P++ VS YPG ++ V++ + + +E+ + Sbjct: 11 FAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQVIEQNMN 70 Query: 73 ELAGIKRIV-TTVHPGSAIVQLTAYDDVQDLPALWQRVRAKAAEAGAQLPAGTLGPFVDD 131 + + + T+ GS + LT D +V+ K A LP + Sbjct: 71 GIDNLMYMSSTSDSAGSVTITLTFQSGT-DPDIAQVQVQNKLQLATPLLPQEVQQQGISV 129 Query: 132 DFGRVS---VASIAVTAPGFSMSEMRGPL-RRMREQLYALPGVEQVKLYGLQDESVYVSF 187 + S VA PG + ++ + +++ L L GV V+L+G ++ + Sbjct: 130 EKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQYAMRIWL 188 Query: 188 DRARLLASGLTPSSVMAQLRAQNVVGSGGQV----AVSG--LALTVATSGEIRTPEQLRG 241 D L LTP V+ QL+ QN + GQ+ A+ G L ++ + PE+ Sbjct: 189 DADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGK 248 Query: 242 VLLSVPGAPAGGARDVTLGELAQVQVMPADPPQSAAVYQGQPAVVVSVSMQPGTNVADFG 301 V L V + V L ++A+V + + A G+PA + + + G N D Sbjct: 249 VTLRVNSDGS----VVRLKDVARV-ELGGENYNVIARINGKPAAGLGIKLATGANALDTA 303 Query: 302 KALRAKLDDTAHELPVGFTQHVVSFQADVVEREMGKMHHVMGETIVIVMAVVMLFLG-WR 360 KA++AKL + P G V+ + ++ + E I++V V+ LFL R Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 361 TGLIVGAIVPLTIFASLIVMRVLNVELQTVSIAAIILALGLLVDNGIVIAEDIERRLV-A 419 LI VP+ + + ++ + T+++ ++LA+GLLVD+ IV+ E++ER ++ Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 420 GEERRQACIDAGRTLATPLLTSSLVIVLAFSPFFFGQTSTNEYLRSLATVLGVTLLGSWL 479 ++A + + L+ ++V+ F P F ST R + + + S L Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 480 LSITVTPLLCMYFAKVHVTKNSDA-------AESRFYR---GYRRVIERVLQHKLLFIGA 529 +++ +TP LC K ++ + + F Y + ++L ++ Sbjct: 484 VALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLI 543 Query: 530 MTAMLAVAVTVLVSIPYDFLPKSDRLQFQMPVTLQAGSDARQTLRTVSELSRW-LGDRHA 588 ++A V + + +P FLP+ D+ F + L AG+ +T + + +++ + L + A Sbjct: 544 YALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKA 603 Query: 589 NPEVVDSIGYVADGGPRIVLGLNPPLPAANQAYFTVSVRPGTD-------IDAVIARVRS 641 N E V ++ + G A N VS++P + +AVI R + Sbjct: 604 NVESVFTVNGFSFSGQ-----------AQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 642 H---VRSHFPALRAEPKRFSLG-ATEAGMAVYRVVGPDEAVLRSSAAAIARALRAVPGTV 697 +R F P LG AT + G L + + P ++ Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 698 -DVQDDWQARIPRYVVQVDQLKARRAGVSSEDIAQALQGRYSGVDATLIRDDGTGVPVVV 756 V+ + ++ ++VDQ KA+ GVS DI Q + G D G + V Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYV 772 Query: 757 RGSTDERAANGNPAD--TLVYPQAGGAPVPLAAVATVLRDSEPSAIQRRNLSRAITVTAR 814 + R P D L A G VP +A T ++R N ++ + Sbjct: 773 QADAKFR---MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGE 829 Query: 815 NPQ----LTATEIVERLSAPIAALKLPPGYRVEIGGELEDSAEANQALLHYMPHALGAIL 870 A ++E L++ KLP G + G + + + + Sbjct: 830 AAPGTSSGDAMALMENLAS-----KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVF 884 Query: 871 LLFVWQFNSFRKLFIVLSAVPFVLIGAALALVMTGYPFGFMATFGLLALAGIIVNNAVLL 930 L + S+ V+ VP ++G LA + GLL G+ NA+L+ Sbjct: 885 LCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILI 944 Query: 931 LERI-EAELADGLPRREAVVAAAVKRLRPIVMTKLTCIVGLVPLMLFAGP---LWTGMAI 986 +E + +G EA + A RLRPI+MT L I+G++PL + G + I Sbjct: 945 VEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGI 1004 Query: 987 TMIGGLALGTLVTLGLIPILYDLL 1010 ++GG+ TL+ + +P+ + ++ Sbjct: 1005 GVMGGMVSATLLAIFFVPVFFVVI 1028 Score = 106 bits (265), Expect = 3e-25 Identities = 87/422 (20%), Positives = 160/422 (37%), Gaps = 28/422 (6%) Query: 619 QAYFTVSVRPGTDIDAVIARVR---SHVRSHFPALRAEPKRFSLGATEAGMAVYRVVGPD 675 T++ + GTD D +V+ P + ++ + + V V + Sbjct: 87 SVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDN 146 Query: 676 EAVLRSS-----AAAIARALRAVPGTVDVQDDWQARIPRYVVQVDQLKARRAGVSSEDIA 730 + A+ + L + G DVQ R + D L ++ D+ Sbjct: 147 PGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKY--KLTPVDVI 204 Query: 731 QALQGRYSGVDATLIRDDGTGVPVVVRGSTDERAANGNPAD---TLVYPQAGGAPVPLAA 787 L+ + + A + + S + NP + + + G+ V L Sbjct: 205 NQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKD 264 Query: 788 VATVLRDSEP-SAIQRRNLSRAITVT-ARNPQLTATEIVERLSAPIAALK--LPPGYRVE 843 VA V E + I R N A + A + + + A +A L+ P G +V Sbjct: 265 VARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVL 324 Query: 844 IGGELEDSAEANQALLHYMPHAL-GAILLLFVWQF---NSFRKLFIVLSAVPFVLIGAAL 899 D+ Q +H + L AI+L+F+ + + R I AVP VL+G Sbjct: 325 Y---PYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFA 381 Query: 900 ALVMTGYPFGFMATFGLLALAGIIVNNAVLLLERIEAELAD-GLPRREAVVAAAVKRLRP 958 L GY + FG++ G++V++A++++E +E + + LP +EA + + Sbjct: 382 ILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGA 441 Query: 959 IVMTKLTCIVGLVPLMLFAG---PLWTGMAITMIGGLALGTLVTLGLIPILYDLLFGLRL 1015 +V + +P+ F G ++ +IT++ +AL LV L L P L L Sbjct: 442 LVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVS 501 Query: 1016 RR 1017 Sbjct: 502 AE 503
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 25.8 bits (56), Expect = 0.032 Identities = 13/34 (38%), Positives = 18/34 (52%), Gaps = 3/34 (8%) Query: 37 TLQVGGQSVPLLGSPTFGSLQAAVDIGSKLAEQY 70 TL + SV L+G+ G LQ +G+ LA Y Sbjct: 243 TLNLASNSVKLMGNVWMGRLQY---VGAYLAPSY 273
>PF06580#Sensor histidine kinase Length = 349 Score = 213 bits (543), Expect = 8e-69 Identities = 102/344 (29%), Positives = 154/344 (44%), Gaps = 17/344 (4%) Query: 2 FWLMQTLGWSLF----LAIAYVARPSEDAVPDGLQLAAVAGFSVGGLLGSLLLRRLYRTL 57 +W Q +GW ++ A + P + S+ GL+ + R + Sbjct: 12 YWYCQGIGWGVYTLTGFGFASLYGS-----PKLHSMIFNIAISLMGLVLTHAYRSFIKRQ 66 Query: 58 QADGYGQVRWLGLLLVASLLAAL--GVDVSVHSVLLGLRGFSPGWMALSEAQPMISGTAL 115 + + +L A ++ + V + LL P L A +I + Sbjct: 67 GWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVV 126 Query: 116 LWPAYIAWSLLYLSISRQTRLAEATRHQNDLRLALKEAQLQRLLGHISPHFTFNTLNNIR 175 + WSLLY +A Q + +EAQL L I+PHF FN LNNIR Sbjct: 127 V---TFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIR 183 Query: 176 ALILIDPALAREQITRFAGTLRYQFTGGEEALVSVDEEMGVVRDYLGLVGMQLGKRLRYA 235 ALIL DP ARE +T + +RY VS+ +E+ VV YL L +Q RL++ Sbjct: 184 ALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFE 243 Query: 236 EQVDAAALLRRVPRFCVQLLVENAIKHGLGLSSSVGDLQVGIAVQDDALHLRVRNSGRLQ 295 Q++ A + +VP VQ LVEN IKHG+ G + + + + L V N+G L Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 296 A---GCSGGTGLANLRQRLRLSFGSRAGLELHEEGTWVVAHVWI 336 S GTGL N+R+RL++ +G+ A ++L E+ V A V I Sbjct: 304 LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.3 bits (115), Expect = 9e-09 Identities = 27/114 (23%), Positives = 46/114 (40%), Gaps = 11/114 (9%) Query: 6 IVEDSELARFELEHQL--KGYPQLRVLGHADDVDSAVQLIESATPEVVFLDIDLPGGNAF 63 + +D R L L GY + + + I + ++V D+ +P NAF Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVR----ITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 64 DVLERLS----RVPRIIFTTAFDAH-ALKAFGYNTVDYLLKPIEPQRLAQAIEK 112 D+L R+ +P ++ + A+KA DYL KP + L I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 553 bits (1427), Expect = 0.0 Identities = 229/1043 (21%), Positives = 443/1043 (42%), Gaps = 59/1043 (5%) Query: 3 VAAFSIRRPVTTIMCFVSLVVVGLIAAFRLPLEALPDISAPFLFVQLPYTGSTPDEVERN 62 +A F IRRP+ + + L++ G +A +LP+ P I+ P + V Y G+ V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 LVRPAEEALATMTGIKRMRSTATADG-ANIFIEFSDWDRDIAIAASDARERLDAVRDDFP 121 + + E+ + + + M ST+ + G I + F D IA + +L P Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQS-GTDPDIAQVQVQNKLQLATPLLP 119 Query: 122 EDLQRFQVFKWSSSDEPVLKVRLAS---QTDLTGAYDMLDREFKRRIERIPGVAKVEISG 178 +++Q+ + SS ++ S T D + K + R+ GV V++ G Sbjct: 120 QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 179 APPNEVEIAIAPDRLTAHDLSLNDLSERLGKLNFSVSAGQI------DDNGQRIRVQPIG 232 A + I + D L + L+ D+ +L N ++AGQ+ + Sbjct: 180 AQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 233 ELRDLQELRELVLNAKG----VRLGDIAEVRLKPTRMNYGRRLDGRPAIGLDVYKERSAN 288 ++ +E ++ L VRL D+A V L N R++G+PA GL + AN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 289 LVEVSKAALKEVEDIRAQ-PALRDVQVKVIDNQGKAVTSSLAELAEAGAVGLLLSITVLF 347 ++ +KA ++ +++ P ++V + V S+ E+ + ++L V++ Sbjct: 299 ALDTAKAIKAKLAELQPFFPQ--GMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMY 356 Query: 348 FFLRHWPSTLMVTLAIPICFAITLGFMYFVGVTLNILTMMGLLLAVGMLVDNAVVVVESI 407 FL++ +TL+ T+A+P+ T + G ++N LTM G++LA+G+LVD+A+VVVE++ Sbjct: 357 LFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV 416 Query: 408 YQERERMPDQPQRAALLGTRSVAIALSAGTLCHCIVFVPNLFGETNNISIFMAQIAITIS 467 + P+ A + AL + VF+P + + Q +ITI Sbjct: 417 ERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIP-MAFFGGSTGAIYRQFSITIV 475 Query: 468 VSLLASWLVAISLIPMLSARMKTPPMVTSEHG------------VIARLQRRYATLLAWT 515 ++ S LVA+ L P L A + P V++EH Y + Sbjct: 476 SAMALSVLVALILTPALCATLLKP--VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 516 LAHRG-WSVAGIILVSAISLVPMKLTKIDMFGGDGGNEAFIQYQWKGSYTREQLGEEIGR 574 L G + + ++V+ + ++ ++L + D G Q T+E+ + + + Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQG-VFLTMIQLPAGATQERTQKVLDQ 592 Query: 575 VENYLEANRAK--YHITQIYSWFSEVEGSNTVVTFDASKVKDLPPLLEKIRKELPRSART 632 V +Y N + + + + N + F + K + E + + A+ Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKM 652 Query: 633 DYSIGNQG----------DGGNGNQGVQVQLVGDSTDALKALADDVIPLLARRKE----L 678 + G G +L+ + AL LL + L Sbjct: 653 ELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASL 712 Query: 679 RDVHVDTGDRTSELAIRVDRERAAAFGFSAEQVASFVGLALRGTPLREFRRGDNEVPVWV 738 V + + T++ + VD+E+A A G S + + AL GT + +F ++V Sbjct: 713 VSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYV 772 Query: 739 RFAGAEQSKPEDLASFTVRTKDGRSVPLLSLVEVQIRPAATQIGRTNRQTTLTIKANLAE 798 + + PED+ VR+ +G VP + + ++ R N ++ I+ A Sbjct: 773 QADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAP 832 Query: 799 KVTVPEARAAMEAPLKAMRFPAGYSYTFDGGDYQNDGEAMGQMVFNLVIALVMIYVVMAA 858 + +A A ME + PAG Y + G + + Q + I+ V++++ +AA Sbjct: 833 GTSSGDAMALMENLASKL--PAGIGYDW-TGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 859 VFESLLFPAAIMSGVLFSIFGVFWLFWITGTSFGIMSFIGILVLMGVVVNNGIVMIEHIN 918 ++ES P ++M V I GV + + +G+L +G+ N I+++E Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 919 NLRRR-GMGRTQALVEGSRERLRPIMMTMGTAILAMVPISLTSTTMFSDGPPYFPMARAI 977 +L + G G +A + R RLRPI+MT IL ++P+++++ + + Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGA---GSGAQNAVGIGV 1006 Query: 978 AGGLAFSTVVSLLFLPTIYAILD 1000 GG+ +T++++ F+P + ++ Sbjct: 1007 MGGMVSATLLAIFFVPVFFVVIR 1029
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 663 bits (1711), Expect = 0.0 Identities = 261/1143 (22%), Positives = 481/1143 (42%), Gaps = 138/1143 (12%) Query: 24 LVAFATRRRVTIAMITVTMLLFGLIALRSLKVNLLPDLSYPTLTVRTEYTGAAPAEIETL 83 + F RR + ++ + +++ G +A+ L V P ++ P ++V Y GA ++ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 84 VTEPVEEAVGVVKNLRKLKSIS-RTGQSDVVLEFAWGTNMDQASLEVRDKMEAL--SLPL 140 VT+ +E+ + + NL + S S G + L F GT+ D A ++V++K++ LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 141 ETKPPVLLRFNPSTEPIMRLALSPKQAPASDTDAIRQLTGLRRYADEDLKKKLEPVAGVA 200 E + + S+ +M + + Y ++K L + GV Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFV-------SDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 201 AVKVGGGLEDEIQVDIDQQKLAQLNLPIDNVITRLKEENVNISGGRL------EEGSQRY 254 V++ G + +++ +D L + L +VI +LK +N I+ G+L Sbjct: 174 DVQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 255 LVRTVNQFVDLDEIRNMLVTTQSSSGSAAEAAMQQMYAIAASTGSQAALAAAAEVQSTSS 314 + +F + +E + + S Sbjct: 233 SIIAQTRFKNPEEFGKVTLRVNSD------------------------------------ 256 Query: 315 SSSSSIAGGMPVRLKDVAQVRQGYKEREAIIRLGGKEAVELAIYKEGDANTVSTAAALRK 374 G VRLKDVA+V G + I R+ GK A L I AN + TA A++ Sbjct: 257 --------GSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKA 308 Query: 375 RLEQLKATVPGDVEITTIEDQSHFIEHAISDVKKDAVIGGVLAILIIFLFLRDGWSTFVI 434 +L +L+ P +++ D + F++ +I +V K +L L+++LFL++ +T + Sbjct: 309 KLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIP 368 Query: 435 SLSLPVSIITTFFFMGQLGLSLNVMSLGGLALATGLVVDDSIVVLESIAKA-RERGLSVL 493 ++++PV ++ TF + G S+N +++ G+ LA GL+VDD+IVV+E++ + E L Sbjct: 369 TIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPK 428 Query: 494 DAAIAGTREVSMAVMASTLTTIAVFLPLVFVEGIAGQLFRDQALTVAIAIAISLVVSMTL 553 +A ++ A++ + AVF+P+ F G G ++R ++T+ A+A+S++V++ L Sbjct: 429 EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALIL 488 Query: 554 IPMLSSLKGAPPMAFPDEPSHPQWQPEQRWLKPVAAGRRGAGASMRYGFFGAAWAVVKVW 613 P L + LKPV+A + GFFG Sbjct: 489 TPALCA----------------------TLLKPVSAEHH----ENKGGFFGWFNTT---- 518 Query: 614 RGLSRVVGPVMRKASDLAMAPYARAERGYLGILPAALRRPWLVLGLAAAAFIGTALLVPM 673 + + Y + L L + A G +L Sbjct: 519 ---------------------FDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLR 557 Query: 674 LGADLIPQLAQDRFEMTVKLPSGTPLAQTDAVVRELQ--LAHDKDPGIASLYGVSGSGTR 731 L + +P+ Q F ++LP+G +T V+ ++ ++ + S++ V+G Sbjct: 558 LPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSF- 616 Query: 732 LDANPTESGENIGKLTVVMAG-----GGSPAVEAAATERLRSSMVGHPGAQV-DFARPAL 785 + +N G V + G + EA R + + V F PA+ Sbjct: 617 -----SGQAQNAGMAFVSLKPWEERNGDENSAEAVI-HRAKMELGKIRDGFVIPFNMPAI 670 Query: 786 FSF--STPLEVEL---RGQDLGELERAGQKLAAMLRAN-GHYADVKSTVEEGFPEIQIRF 839 +T + EL G L +A +L M + V+ E + ++ Sbjct: 671 VELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEV 730 Query: 840 DQERAGALGLTTRQIADVIVKKVRGDVATRYSFRDRKIDVLVRAQHSDRASVDAIRQLIV 899 DQE+A ALG++ I I + G + R R + V+A R + + +L V Sbjct: 731 DQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYV 790 Query: 900 NPGSSRPVRLAAVAEVLATTGPSEIHRADQTRVAIVSASL-KDIDLGGAVREVETMVRKD 958 + V +A G + R + + G A+ +E + K Sbjct: 791 RSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKL 850 Query: 959 PLAAGVGMHIGGQGEELAQSVKSLLFAFGLAIFLVYLVMASQFESLLHPFVILFTIPLAM 1018 P AG+G G + S ++ +V+L +A+ +ES P ++ +PL + Sbjct: 851 P--AGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGI 908 Query: 1019 VGAVLALLMTGKPISVVVFIGLILLVGLVTKNAIILIDKVNQLRE-DGVPKREALIEGAR 1077 VG +LA + + V +GL+ +GL KNAI++++ L E +G EA + R Sbjct: 909 VGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVR 968 Query: 1078 SRLRPIIMTTLCTLFGFLPLAVAMGEGAEVRAPMAITVIGGLLVSTLLTLLVIPVVYDLL 1137 RLRPI+MT+L + G LPLA++ G G+ + + I V+GG++ +TLL + +PV + ++ Sbjct: 969 MRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028 Query: 1138 DRR 1140 R Sbjct: 1029 RRC 1031
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 52.9 bits (127), Expect = 9e-10 Identities = 39/225 (17%), Positives = 82/225 (36%), Gaps = 33/225 (14%) Query: 61 TAALEPRAEAQVVAKTSRVALSVMVEEGQKVSAGQALVRLDPDRAHL--AVAQSEAQLRK 118 Q +AK +V+ +E + V A L + + ++ + + Sbjct: 237 LDDFSSLLHKQAIAK-----HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 119 LENSYRRATQLVGQQLVSA-ADVDQLKFDVENSRAQHRLAALELSYTTVQAPISGVIASR 177 + ++ + +L ++ L ++ + + + ++AP+S + Sbjct: 292 VTQLFKN---EILDKLRQTTDNIGLLTLELAKNEER-------QQASVIRAPVSVKVQQL 341 Query: 178 SIKT-GNFVQINTPIFRIV-DDSQLEATLNVPERELATLKSGQPVTLLADALPGQQF--- 232 + T G V + IV +D LE T V +++ + GQ + +A P ++ Sbjct: 342 KVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYL 401 Query: 233 VGKVDRIAP--VVDSGSGT-FRVVCAFGQGAEA-------LQPGM 267 VGKV I + D G F V+ + + + L GM Sbjct: 402 VGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGM 446 Score = 39.8 bits (93), Expect = 1e-05 Identities = 16/74 (21%), Positives = 33/74 (44%), Gaps = 9/74 (12%) Query: 72 VVAKTSRVALSVMVEEGQKVSAGQALVRLDPDRAHLAVAQSEAQLRKLENSYR--RATQL 129 + + + ++V+EG+ V G L++L +EA K ++S R Q Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTA-------LGAEADTLKTQSSLLQARLEQT 151 Query: 130 VGQQLVSAADVDQL 143 Q L + ++++L Sbjct: 152 RYQILSRSIELNKL 165
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 41.0 bits (96), Expect = 3e-07 Identities = 27/123 (21%), Positives = 50/123 (40%), Gaps = 5/123 (4%) Query: 1 MRGVRVLVVENDDMNAMLLDLQLVQAGAVVMGPVGEVRDALQLIADDAPDIAVLDYRLGN 60 M G +LV ++D +L+ L +AG V + IA D+ V D + + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 GETSEPVARLLSER-GIPFVLATGVA-IGSIPSGFERGVI--LIKPYLSEELVGALSKAR 116 + + R+ R +P ++ + + E+G L KP+ EL+G + +A Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 117 ESR 119 Sbjct: 120 AEP 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 2e-17 Identities = 30/126 (23%), Positives = 56/126 (44%), Gaps = 4/126 (3%) Query: 1002 RVLLVDDDQDSREAVMQFLMLAGAQVQAAGSVDAAEHCLANAHFDVLVSDIAMPLRDGYD 1061 +L+ DDD R + Q L AG V+ + +A D++V+D+ MP + +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 1062 LIRTVRSGRADLPRHIPAVALTAYVREEDRDRAVVAGFDAHMGKPVEPPGLVDLIERVIL 1121 L+ ++ R DLP + ++A +A G ++ KP + L+ +I R + Sbjct: 65 LLPRIKKARPDLPV----LVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 1122 PTRSTR 1127 + Sbjct: 121 EPKRRP 126
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.5 bits (74), Expect = 0.003 Identities = 35/186 (18%), Positives = 59/186 (31%), Gaps = 19/186 (10%) Query: 144 AQALQKWREENA-PWLDMPAFGLNRN----HQSRLQKLARAQ----QEFQAQSEAYGEQL 194 Q L + E N P L +P +N RL L + Q Q + Q E ++ Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212 Query: 195 KAAIEQAFARFASRLSEHESSGSQLTSARALFD------LWIEAAEESYADVALSEQFRK 248 +A AR + S+L +L + E Y + + Sbjct: 213 RAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEA---VNELR 269 Query: 249 VYGGFANAHMRLRAALQEEVEQLSERFGMPTRSEMDAAHRRIAELE-RLVRRMLRNAASP 307 VY + +EE + +++ F ++ I L L + R AS Sbjct: 270 VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASV 329 Query: 308 ASKPAA 313 P + Sbjct: 330 IRAPVS 335
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (254), Expect = 3e-28 Identities = 73/254 (28%), Positives = 106/254 (41%), Gaps = 13/254 (5%) Query: 4 ILITGAGSGIGAGIATQLAADGHHLLVSDVQLAAAERTADALRQAGGSAEALALDVTDAD 63 ITGA GIG +A LA+ G H+ D E+ +L+ AEA DV D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 64 SIAQALASASRAPQ---VLVNNAGLQHVAALEEFPMQQWALLVDVMLTGAARLSRAVLPG 120 +I + A R +LVN AG+ + ++W V TG SR+V Sbjct: 71 AIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKY 130 Query: 121 MRAAGYGRIVNIGSIHSLVASPYKSAYVAAKHGLVGLAKVIALETADCDITVNTLCPSYV 180 M G IV +GS + V +AY ++K V K + LE A+ +I N + P Sbjct: 131 MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGST 190 Query: 181 RT----PLVERQIADQARIRGITEDAVVRDVMLKPMPKGAFIDYDELAGTVAFLMSHAAR 236 T L + + I+G E +P ++A V FL+S A Sbjct: 191 ETDMQWSLWADENGAEQVIKGSLETFKT------GIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 237 NITGQALAIDGGWT 250 +IT L +DGG T Sbjct: 245 HITMHNLCVDGGAT 258
>BACTRLTOXIN#Bacterial toxin signature. Length = 266 Score = 28.7 bits (64), Expect = 0.010 Identities = 7/30 (23%), Positives = 14/30 (46%) Query: 73 YDLCDPVTGEPDPSAYVRLYRDARQAETTH 102 YD+ + D S Y+ +Y D + ++ Sbjct: 225 YDMMPAPGDKFDQSKYLMMYNDNKTVDSKS 254
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 31.6 bits (71), Expect = 0.003 Identities = 14/64 (21%), Positives = 21/64 (32%), Gaps = 2/64 (3%) Query: 3 TIRPVFYVSDGTGITAETIGHSLLTQF--SGFNFVTDRMSFIDDADKARDAAMRVRAAGE 60 + V+ G T+E I S+ F + T S A +V A Sbjct: 78 SKEVSINVNFSVGFTSEFIQASVEYGFGITIGEQNTIERSVSTTAGPNEYVYYKVYATYR 137 Query: 61 RYQV 64 +YQ Sbjct: 138 KYQA 141
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 278 bits (714), Expect = 2e-86 Identities = 137/574 (23%), Positives = 234/574 (40%), Gaps = 89/574 (15%) Query: 260 KAIRMVYSDVPGERVRTEDTPVE---LRSTFSISDEDVQELSKQAL---------VIEKH 307 KA + +V E+ D E L + S E+++ + Q + H Sbjct: 18 KAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAAH 77 Query: 308 YGRPMDIEWAKDGVSGKLFIVQARPETVKSRSHATQIERFALEAKGAKILAEGRAVGAKI 367 D E + GK+ Q E + F E+ + + E RA A I Sbjct: 78 LLVLDDPELVDG-IKGKIENEQMNAEYALKEVSDMFVSMF--ESMDNEYMKE-RA--ADI 131 Query: 368 GSGVARVVRSLDDMNRVQAGD-----VLIA-DMTDPDWEPVMK-RASAIVTNRGGRTCHA 420 RV+ L + V+IA D+T D + K T+ GGRT H+ Sbjct: 132 RDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHS 191 Query: 421 AIIARELGVPAVVGSGNATDVLSDGQEVTVSCAEG---------DTGFIYDGLLPFERTT 471 AI++R L +PAVVG+ T+ + G V V EG + + FE+ Sbjct: 192 AIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQK 251 Query: 472 TDLGNMPPAP--------LKIMMNVANPERAFDFGQLPNAGIGLARLEMIIAAHIGIHPN 523 + + P +++ N+ P+ GIGL R E + + Sbjct: 252 QEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLYMDR-----D 306 Query: 524 ALLEYDKQDADVRKKIDAKIAGYGDPVSFYVNRLAEGIATLTASVAPNTVIVRLSDFKSN 583 L ++Q ++ + G PV ++R D + Sbjct: 307 QLPTEEEQFEAYKEVVQRM---DGKPV-----------------------VIRTLDIGGD 340 Query: 584 EYANLIGGSRYEPHEENPMIGFRGASRYVDPSFTKAFALECKAVLKVRNEMGLDNLWVMI 643 + + + P E NP +GFR ++ F + +A+L+ NL VM Sbjct: 341 KELSYL----QLPKELNPFLGFRAIRLCLE--KQDIFRTQLRALLRAS---TYGNLKVMF 391 Query: 644 PFVRTLEEGRKVIEVLEQNGLKQGENG------LKIIMMCELPSNALLADEFLEIFDGFS 697 P + TLEE R+ ++++ K G +++ +M E+PS A+ A+ F + D FS Sbjct: 392 PMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDFFS 451 Query: 698 IGSNDLTQLTLGLDRDSSIVAHLFDERNPAVKKLLSMAIKSARAKGKYVGICGQGPSDHP 757 IG+NDL Q T+ DR + V++L+ +PA+ +L+ M IK+A ++GK+VG+CG+ D Sbjct: 452 IGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD-E 510 Query: 758 ELAEWLMQEGIESVSLNPDTVVDTWLRLAKLKSE 791 L+ G++ S++ +++ +L KL E Sbjct: 511 VAIPLLLGLGLDEFSMSATSILPARSQLLKLSKE 544
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 9e-06 Identities = 18/84 (21%), Positives = 29/84 (34%), Gaps = 10/84 (11%) Query: 609 NALRHA---CAGEVHLRLHSI-DGDSFRLEVSDDGDGFEPEGPR--GLGLIVMRERAQTV 662 N ++H + L D + LEV + G G GL +RER Q + Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQML 325 Query: 663 GG---TLAIESAPGAGTRVTLRLP 683 G + + G + +P Sbjct: 326 YGTEAQIKLSEKQG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99 bits (249), Expect = 2e-24 Identities = 34/115 (29%), Positives = 56/115 (48%), Gaps = 1/115 (0%) Query: 447 TLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRDAFDLLATNDVQVILSDQRMSDMSGTE 506 T+L+ DD+ + L + R GY + N + +A D ++++D M D + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 507 FLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQA 561 L R+K PD LV+S T +A +GA Y +L KP++ EL I +A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGA-YDYLPKPFDLTELIGIIGRA 118
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.2 bits (62), Expect = 0.007 Identities = 15/66 (22%), Positives = 24/66 (36%), Gaps = 2/66 (3%) Query: 35 DKLSALQALEAAMPAGEEERLRELAEANRANGALLARRRREVNWALRHLGRTESAPSYDA 94 + +S+LQ + A + A R A A+R+ E R +A +Y Sbjct: 195 EAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEE--QARQQAAIRAANTYAM 252 Query: 95 KGQSSV 100 SV Sbjct: 253 PANGSV 258
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.7 bits (90), Expect = 2e-05 Identities = 15/75 (20%), Positives = 29/75 (38%), Gaps = 9/75 (12%) Query: 184 VLVVDDSRVARQQIRSVLDQLGVSATLLSDGRQALDHLLQVAASGENPADRYAMVISDIE 243 +LV DD R + L + G + S+ + A +V++D+ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA---------AGDGDLVVTDVV 56 Query: 244 MPAMDGYTLTTEIRR 258 MP + + L I++ Sbjct: 57 MPDENAFDLLPRIKK 71
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 46.1 bits (109), Expect = 2e-07 Identities = 25/69 (36%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 2 GFNTSLSGINAANADLNVTSNNIANVNTTGFKESRAEFADMFQSTSYGLSRNAVGSGVRV 61 N ++SG+NAA A LN SNNI++ N G+ A Q+ S + VG+GV V Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA---QANSTLGAGGWVGNGVYV 59 Query: 62 SNVAQQFSQ 70 S V +++ Sbjct: 60 SGVQREYDA 68 Score = 44.2 bits (104), Expect = 7e-07 Identities = 31/188 (16%), Positives = 69/188 (36%), Gaps = 16/188 (8%) Query: 232 LQFSDTGALTTPANGIIAMDPFTPSTGAGVLN-MQLNVTGSTQYGEAFALRDTRQDGYAS 290 + F + T + G + ++L TG+ ++F L+ A Sbjct: 363 ISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSD---AI 419 Query: 291 GKLNEISIDTSGVVFARYSNGADKPLGQVALSSFVNPQGLQSQGNNMWA-ESY------- 342 ++ + D + + A + D + ++ G ++Y Sbjct: 420 VNMDVLITDEAKIAMASEEDAGDSDNRNGQ-ALLDLQSNSKTVGGAKSFNDAYASLVSDI 478 Query: 343 ---TSGAARTGAPDTSDLGQIESGSLEASTVDLTEQLVNMIVAQRNFQANSQMISTQDQV 399 T+ + A + + Q+ + S V+L E+ N+ Q+ + AN+Q++ T + + Sbjct: 479 GNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAI 538 Query: 400 TQTIINIR 407 +INIR Sbjct: 539 FDALINIR 546
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 29.9 bits (67), Expect = 0.011 Identities = 9/31 (29%), Positives = 18/31 (58%) Query: 5 LYVAMTGARASLQAQGTVSHNLANVDTVGFK 35 + AM+G A+ A T S+N+++ + G+ Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYT 34
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 39.2 bits (91), Expect = 1e-05 Identities = 12/41 (29%), Positives = 20/41 (48%) Query: 219 LEGSNVNTVEELVSMIETQRAYEMNAKAISTTDSMLGYLNN 259 S VN EE ++ Q+ Y NA+ + T +++ L N Sbjct: 504 QSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 37.6 bits (87), Expect = 3e-05 Identities = 19/82 (23%), Positives = 31/82 (37%), Gaps = 20/82 (24%) Query: 5 LWVAKTGLDAQQTRMSVISNNLANTNTTGFKRDRAAFEDLLYQQVRAPGGSTSAQTQLPT 64 + A +GL+A Q ++ SNN+++ N G+ R T T Sbjct: 4 INNAMSGLNAAQAALNTASNNISSYNVAGYTRQT-----------------TIMAQANST 46 Query: 65 ---GLQLGTGVRVVSTFKGFDQ 83 G +G GV V + +D Sbjct: 47 LGAGGWVGNGVYVSGVQREYDA 68
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 145 bits (368), Expect = 1e-45 Identities = 78/199 (39%), Positives = 106/199 (53%), Gaps = 15/199 (7%) Query: 39 VPVVAPVA-----QPTAGAIYAAGPGLNLYGDRRARDVGDLLTVNLVESTTASSTANTSI 93 VP PVA Q Y P L+ DRR R++GD LT+ L E+ +AS +++ + Sbjct: 40 VPGPTPVANGSIFQSAQPINYGYQP---LFEDRRPRNIGDTLTIVLQENVSASKSSSANA 96 Query: 94 SKKDATTM---AAPTLLGAPLTVGGLNVLENSTSGDRSFAGKGNTAQSNRMQGSVTVTVM 150 S+ T P L +V SG +F GKG SN G++TVTV Sbjct: 97 SRDGKTNFGFDTVPRYLQGLFGNARADV---EASGGNTFNGKGGANASNTFSGTLTVTVD 153 Query: 151 QRLPNGNLVIQGQKNLRLTQGDELVQVQGIVRAADIAPDNTVPSSKVADARIAYGGRGAI 210 Q L NGNL + G+K + + QG E ++ G+V I+ NTVPS++VADARI Y G G I Sbjct: 154 QVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYI 213 Query: 211 AQSNAMGWLSRFFNSRLSP 229 ++ MGWL RFF + LSP Sbjct: 214 NEAQNMGWLQRFFLN-LSP 231
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 360 bits (926), Expect = e-125 Identities = 157/364 (43%), Positives = 220/364 (60%), Gaps = 9/364 (2%) Query: 10 LLAAAVALCAIAAPASAERIKDLAQVGGVRGNALVGYGLVVGLDGSGDRTSQAPFTVQSL 69 + +A L A A RIKD+A + R N L+GYGLVVGL G+GD +PFT QS+ Sbjct: 12 VFSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSM 71 Query: 70 KNLLGELGVNVPANVNPQLKNVAAVAIHAELPPFAKPGQPIDVTVSSIANAVSLRGGSLL 129 + +L LG+ KN+AAV + A LPPFA PG +DVTVSS+ +A SLRGG+L+ Sbjct: 72 RAMLQNLGITTQGG-QSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLI 130 Query: 130 MAPLKGADGQVYAMAQGNLVVGGFGAQGKDGSRVSVNVPSVGRIPNGATVERALPDVFAG 189 M L GADGQ+YA+AQG L+V GF AQG D + ++ V + R+PNGA +ER LP F Sbjct: 131 MTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKD 189 Query: 190 TGEITLNLHQNDFTTVSRMVAAIDS----SFGAGTARAVDGVTVAVRSPTDPGARIGLLS 245 + + L L DF+T R+ +++ +G A D +AV+ P L++ Sbjct: 190 SVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMA 248 Query: 246 RLENVELSPGDAPAKVVVNARTGTVVIGQLVRVMPAAIAHGSLTVTISENTNVSQPGAFS 305 +EN+ + D PAKVV+N RTGT+VIG VR+ A+++G+LTV ++E+ V QP FS Sbjct: 249 EIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFS 307 Query: 306 GGRTAVTQQSTITATSEGSRMFKFEGGTTLDQIVRAVNEVGAAPGDLVAILEALKQAGAL 365 G+TAV Q+ I A EGS++ E G L +V +N +G ++AIL+ +K AGAL Sbjct: 308 RGQTAVQPQTDIMAMQEGSKVAIVE-GPDLRTLVAGLNSIGLKADGIIAILQGIKSAGAL 366 Query: 366 TAEL 369 AEL Sbjct: 367 QAEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 129 bits (326), Expect = 8e-37 Identities = 63/140 (45%), Positives = 82/140 (58%), Gaps = 4/140 (2%) Query: 218 FVAKIWTHAQKAARELGVDPRALVAQAALETGWGRRGI--GNGGDSNNLFGIKATG-WSG 274 F+A++ AQ A+++ GV ++AQAALE+GWG+R I NG S NLFG+KA+G W G Sbjct: 152 FLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKG 211 Query: 275 DKVTTGTHEYVNGVKTTETADFRAYGSAEESFADYVRLLKNNSRYQTALQAGTDIKGFAR 334 T EY NG A FR Y S E+ +DYV LL N RY A+ + A+ Sbjct: 212 PVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRY-AAVTTAASAEQGAQ 270 Query: 335 GLQQAGYATDPGYAAKIAAI 354 LQ AGYATDP YA K+ + Sbjct: 271 ALQDAGYATDPHYARKLTNM 290 Score = 73.2 bits (179), Expect = 1e-16 Identities = 56/174 (32%), Positives = 87/174 (50%), Gaps = 14/174 (8%) Query: 4 AASPIDLNPSTKADPA-KIDKVSRQLEGQFAQMLVKSMRDASSGDPMFPGQNQ-MFREMY 61 A S +L DPA I V+RQ+EG F QM++KSMRDA D +F ++ ++ MY Sbjct: 15 AQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDGLFSSEHTRLYTSMY 74 Query: 62 DQQMAKALTDGKGLGLSAMISKQLSGDTGGPA-------LNTSLNTAEAAKAYALVAGKR 114 DQQ+A+ +T GKGLGL+ M+ KQ++ + P + L T + AL + Sbjct: 75 DQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQNQALSQLVQ 134 Query: 115 DASLPLPARDGAATGTTTSSVAKAALG---AGNLSGIGMSQVLDLIAGRTGAGE 165 A D + G + + +A+ +L A SG+ +L A +G G+ Sbjct: 135 KAVPRNY--DDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQ 186
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 227 bits (580), Expect = 7e-69 Identities = 141/437 (32%), Positives = 219/437 (50%), Gaps = 8/437 (1%) Query: 2 SIMSTGTSALIAFQRALSTVSHNVANINTEGYSRQRVEFATRTPTDMGYAFVGNGAKITD 61 S+++ S L A Q AL+T S+N+++ N GY+RQ A T +VGNG ++ Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSG 61 Query: 62 VGRVADQLAISRLLDSGGELSRLQQLSSLSNRVDALYSNTATNVAGLWSNFFDSTSAVSS 121 V R D ++L + + S L +++D + S + +++A +FF S + S Sbjct: 62 VQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLVS 121 Query: 122 NASSTAERQSMLDSGNSLATRFKQLNGQMDSLSNEVNSGLTSSVDEVNRLTQQIAKLNGT 181 NA A RQ+++ L +FK + + +VN + +SVD++N +QIA LN Sbjct: 122 NAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLNDQ 181 Query: 182 I----GSSAQAAAPDMLDQRDALVSKLVGFTGGTAVIQDGGFMNVFTAGGQPLVVGTTSS 237 I G A A+ ++LDQRD LVS+L G +QDGG N+ A G LV G+T+ Sbjct: 182 ISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTAR 241 Query: 238 KLTTVADPYQPTKLQVAMQTQGQNVSLSASSL--GGQIGGLLEFRSSVLEPTQAELGRLA 295 +L V P++ VA L G +GG+L FRS L+ T+ LG+LA Sbjct: 242 QLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQLA 301 Query: 296 VGMASTFNAGHSQGMDLYGAMGGNFFNIGSPTVAANPSNAGSASLSASFSNVSAVDGQNV 355 + A FN H G D G G +FF IG P V N N G ++ A+ ++ SAV + Sbjct: 302 LAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATDY 361 Query: 356 TLSFDGTNWKAINASTGSAVPMTGTGTAADPLVLNGVSMVVGGTPASGDKFLLQPTAGLA 415 +SFD W+ ++ + T T A + +G+ + GTPA D F L+P + Sbjct: 362 KISFDNNQWQVTRLASNTT--FTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAI 419 Query: 416 GSLSVAITDPSRIAAAT 432 ++ V ITD ++IA A+ Sbjct: 420 VNMDVLITDEAKIAMAS 436 Score = 82.3 bits (203), Expect = 1e-18 Identities = 38/105 (36%), Positives = 56/105 (53%) Query: 517 AGSSDNGNAKLLANIDDAKALSGGTVTLNGALSGLTTSVGSAARAASYSADAQKVINDQA 576 AG SDN N + L ++ GG + N A + L + +G+ S+ Q + Q Sbjct: 440 AGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQL 499 Query: 577 QASRDSISGVNLDEEAANMLKLQQAYQAAAQMISTADTIFQAILG 621 + SISGVNLDEE N+ + QQ Y A AQ++ TA+ IF A++ Sbjct: 500 SNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLAGELLIN#Flagellin signature. Length = 507 Score = 58.9 bits (142), Expect = 1e-11 Identities = 62/349 (17%), Positives = 112/349 (32%), Gaps = 6/349 (1%) Query: 4 RISTSMMYSQSVASMGAKQSRLNQLESQLSSGQRLVTAKDDPVAAGTAVGLDRALAAITR 63 I+T+ + + ++ QS L+ +LSSG R+ +AKDD A + +T+ Sbjct: 3 VINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQ 62 Query: 64 FGENANNVQNRLGLQENALSQAGDKMARVTELAVQASNSSLSPDDRKAIASELTALRESM 123 NAN+ + E AL++ + + RV EL+VQA+N + S D K+I E+ E + Sbjct: 63 ASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEI 122 Query: 124 VSLANSTDGTGRYLFGGTADGSAPFIKSNG---SVTYNGDQTQKQVEVAPDTFVSDTLPG 180 ++N T G + ++G ++ + + Sbjct: 123 DRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEATV 182 Query: 181 SEIFMRIRTGDGTVDAHANAANTGTGLLLDFSRDASTGSWNGGSYSVQFTAADTYEVRDS 240 ++ + G A + +T V Sbjct: 183 GDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTDDAE 242 Query: 241 TNTVVGTGTYKEG--EDINAAGVRMRISGAPAVGDSFQIGASGTKDVFSTID-DLVGALN 297 NT V + A + I G G + T D + D + + Sbjct: 243 NNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKVSTT 302 Query: 298 SDTLTAPQKAAMINTLQSSMRDITQASSKMIDARASGGAQLSAIDNANS 346 + A I +++ T SSK + G N Sbjct: 303 INGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNE 351 Score = 38.1 bits (88), Expect = 5e-05 Identities = 50/269 (18%), Positives = 85/269 (31%), Gaps = 1/269 (0%) Query: 127 ANSTDGTGRYLFGGTADGSAPFIKSNGSVTYNGDQTQKQVEVAPDTFVSDTLPGSEIFMR 186 AN T D + G+ + DTF + + Sbjct: 232 ANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKT 291 Query: 187 IRTGDGTVDAHANAANTGTGLLLDFSRDASTGSWNGGSYSVQFTAADTYEVRDSTNTVVG 246 G+G V N + + A+ + S +T+ + T Sbjct: 292 GNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNE 351 Query: 247 TGTYKEGEDINAAGVRMRISGAPAVGDSFQIGASGTKDVFSTIDDLVGALNSDTLTAPQK 306 + + E NA +I+ A + G T + D A TL Sbjct: 352 SAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFID-KTASGVSTLINEDA 410 Query: 307 AAMINTLQSSMRDITQASSKMIDARASGGAQLSAIDNANSLLESNEVTLKTSLSSIRDLD 366 AA + + + I A SK+ R+S GA + D+A + L + L ++ S I D D Sbjct: 411 AAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDAD 470 Query: 367 YASAIGQYQLEKASLQAAQTIFQQMQSSS 395 YA+ + + QA ++ Q Sbjct: 471 YATEVSNMSKAQILQQAGTSVLAQANQVP 499
>FLAGELLIN#Flagellin signature. Length = 507 Score = 141 bits (356), Expect = 1e-39 Identities = 125/360 (34%), Positives = 178/360 (49%), Gaps = 10/360 (2%) Query: 2 AQVINTNVMSLNAQRNLNTSSASMSTSIQRLSSGLRINSAKDDAAGLAISERFTTQIRGL 61 AQVINTN +SL Q NLN S +S+S++I+RLSSGLRINSAKDDAAG AI+ RFT+ I+GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 DVASRNANDGISLAQTAEGAMVEIGNNLQRIRELSVQSSNATNSATDREALNSEVKQLTS 121 ASRNANDGIS+AQT EGA+ EI NNLQR+RELSVQ++N TNS +D +++ E++Q Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVANQTNFNGTKLLDGSFSGALFQVGADAGQTIGINSIVDANVDSLGKANFAAAVSG 181 EIDRV+NQT FNG K+L QVGA+ G+TI I + +V SLG F Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQ-MKIQVGANDGETITI-DLQKIDVKSLGLDGFNVNGPK 178 Query: 182 AGVTGTATASGSITGISLAFNDASGTAKTVTIGDVKIANGDDAATINKKVASAINDKLDQ 241 G +S + + + + + +K +A N +L Sbjct: 179 EATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTT 238 Query: 242 TGMYASIDTSGNLKLESLKAGQDFTSLTMG--------TSSATGVTVGAGLQTASAASGS 293 + +S + ++ T GVT +T + +G Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGK 298 Query: 294 TAVTLTDLDISTFAGSQQALEIVDKALTAVNSSRADMGAVQNRFTSTIANLSATSENLSA 353 + T+ ++ A A T +S V +FT + +++ Sbjct: 299 VSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDL 358 Score = 97.8 bits (243), Expect = 3e-24 Identities = 72/340 (21%), Positives = 129/340 (37%), Gaps = 3/340 (0%) Query: 60 GLDVASRNANDGISLAQTAEGAMVEIGNNLQRIRELSVQSSNATNSATDREALNSEVKQL 119 G +V L + + + + +S A + T + +V Sbjct: 171 GFNVNGPKEATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVN 230 Query: 120 TSEIDRVANQTNFNGTKLLDGSFSGALFQVGADAGQTIGINSIVDANVDSLGKANFAAAV 179 + + N L + A A D G Sbjct: 231 AANGQLTTDDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTK 290 Query: 180 SGAGVTGTATASGSITGISLAFNDASGTAKTVTIGDVKIANGDDAATINKKVASAINDKL 239 +G G + + + ++L D + A V ++ + + +N + K Sbjct: 291 TGNDGNGKVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKN 350 Query: 240 DQTGMYASIDTSGNLKLESLKAGQDFTSLTMGTSSATGVTVGAGLQTASAASGSTAVTLT 299 + + + ++ + ++ VT+ + + + Sbjct: 351 ESAKLSDLEANNA---VKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLIN 407 Query: 300 DLDISTFAGSQQALEIVDKALTAVNSSRADMGAVQNRFTSTIANLSATSENLSASRSRIR 359 + + + L +D AL+ V++ R+ +GA+QNRF S I NL T NL+++RSRI Sbjct: 408 EDAAAAKKSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIE 467 Query: 360 DTDYAKETAELTRTQILQQAGTAMLAQAKSVPQNVLSLLQ 399 D DYA E + +++ QILQQAGT++LAQA VPQNVLSLL+ Sbjct: 468 DADYATEVSNMSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.8 bits (176), Expect = 6e-17 Identities = 35/160 (21%), Positives = 66/160 (41%), Gaps = 9/160 (5%) Query: 2 RVIIVDDHTLVRAGLSRLLQTFAGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRSG 61 +++ DD +R L++ L + AG DV SNA + DLV+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 LDAMTDVLRAAPRTHVVMMSMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAGQ 121 D + + +A P V++MS + + A ++GA ++ K EL + A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA---- 118 Query: 122 VFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIGR 161 + + + + + S +EI R + R Sbjct: 119 ---LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 56.8 bits (137), Expect = 1e-12 Identities = 20/118 (16%), Positives = 44/118 (37%), Gaps = 2/118 (1%) Query: 1 MSKLTVLLVDDHEGFINAAMRHFRKVDWLNIVGSAANGLEAIERSESLRPNVVLMDLAMP 60 M+ T+L+ DD + + + V +N + ++V+ D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 EMGGLQATRLIKTQDDPPYIVIASHFDDAEHREHALRAGADNFVSKLSYIQEVMPILE 118 + IK +++ S + A GA +++ K + E++ I+ Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 437 bits (1125), Expect = e-152 Identities = 181/489 (37%), Positives = 255/489 (52%), Gaps = 16/489 (3%) Query: 1 MSESRILLIDSDAVRAERTVSLLEFMDFNPRWVTDGADINPGRHRHDEWMAVMVGSAQDA 60 M+ + IL+ D DA L ++ R ++ A + R ++V Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLW--RWIAAGDGDLVVTDVVMP 58 Query: 61 -AQADKFFDWLADAKLPPPVLLMEGSPSAFAQTHGLHEANVWALDTPLRHAQLEALLRRA 119 A + A+ PVL+M + + L P +L ++ RA Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 S--LKRLDAEHQAGVQQDSGPTGNSEAVTRLRRLIDQVAAFDTTVLVLGESGTGKEVVAR 177 KR ++ + Q G S A+ + R++ ++ D T+++ GESGTGKE+VAR Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 178 AIHQHSPRRDGPFVAINCGAIPPDLLESELFGHEKGAFTGALTTRKGRFEMAEGGTLLLD 237 A+H + RR+GPFVAIN AIP DL+ESELFGHEKGAFTGA T GRFE AEGGTL LD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 238 EIGDMSLPMQVKLLRVLQERSFERVGGGQTIRCNVRVIAATHRNLESRISDGQFREDLFY 297 EIGDM + Q +LLRVLQ+ + VGG IR +VR++AAT+++L+ I+ G FREDL+Y Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 298 RLNVFPIEMPALRERVDDLAMLVQTIAGQLARTGRGEVRFADEALQALRSYDWPGNVREL 357 RLNV P+ +P LR+R +D+ LV+ Q + G RF EAL+ ++++ WPGNVREL Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 358 TNLVERLAVLHPGGLVRVQDLPARYRGDFASAIPVELPPEPELVAAPVEVSALPSNVVTL 417 NLV RL L+P ++ + + R E+P P AA S S V Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRS--------EIPDSPIEKAAARSGSLSISQAVEE 410 Query: 418 QPKTADAEPAATSSLPDDGIDLRGHMANIELALINEALERTQGVVAHAAQLLGLRRTTLV 477 + A +A +E LI AL T+G AA LLGL R TL Sbjct: 411 NMRQYFASFGDA---LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLR 467 Query: 478 EKLRKYGID 486 +K+R+ G+ Sbjct: 468 KKIRELGVS 476
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 241 bits (616), Expect = 5e-82 Identities = 124/228 (54%), Positives = 162/228 (71%), Gaps = 1/228 (0%) Query: 51 PAGSNQLPSLPNVSVGRIGDQPVSLPLQTLLLMTAITLLPSMLLVLTAFTRITIVLGLLR 110 P QLP + + + G Q SLP+QTL+ +T++T +P++LL++T+FTRI IV GLLR Sbjct: 17 PLAFAQLPGITSQPL-PGGGQSWSLPVQTLVFITSLTFIPAILLMMTSFTRIIIVFGLLR 75 Query: 111 QALGTGQTPSNQVLLGLAMFLTALVMMPVWQKMWGAGLQPYLNNQIDFSTAWTLTTQPLR 170 ALGT P NQVLLGLA+FLT +M PV K++ QP+ +I A QPLR Sbjct: 76 NALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKISMQEALEKGAQPLR 135 Query: 171 AFMLAQIRETDLMTFAGMAGDGKYAGPDAVPFPVLVASFVTSELKTAFEIGFLIFIPFVI 230 FML Q RE DL FA +A G GP+AVP +L+ ++VTSELKTAF+IGF IFIPF+I Sbjct: 136 EFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLI 195 Query: 231 IDLVVASVLMSMGMMMLSPMLISAPFKILLFILVDGWVLVVGTLAASF 278 IDLV+ASVLM++GMMM+ P I+ PFK++LF+LVDGW L+VG+LA SF Sbjct: 196 IDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQSF 243
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 43.2 bits (102), Expect = 3e-09 Identities = 17/69 (24%), Positives = 32/69 (46%) Query: 13 GLVTVLWIAGPMLLAVLVVGVVIGVVQAATQLNEPTIAFVAKAVALTATLFATGSMLLGH 72 L VL ++G + ++G+++G+ Q TQL E T+ F K + + LF Sbjct: 11 ALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLSGWYGEV 70 Query: 73 LVEFTIALF 81 L+ + + Sbjct: 71 LLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 124 bits (314), Expect = 1e-36 Identities = 79/239 (33%), Positives = 130/239 (54%), Gaps = 2/239 (0%) Query: 23 WTMLRTGALLTAMPLIGTRAVPGRVRVMLAGTLAMVLAPILPPVPEWDGFTAQAVLSIAR 82 W +LR AL++ P++ R+VP RV++ LA + +AP LP L++ + Sbjct: 18 WPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFSFFALWLAV-Q 76 Query: 83 ELAVGASMGFMLKLMFEAGALAGELVSQSTGLSFAQMSDPMRGVTSGVIAQWFYIGFGLL 142 ++ +G ++GF ++ F A AGE++ GLSFA DP + V+A+ + LL Sbjct: 77 QILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDMLALLL 136 Query: 143 FFAANGHLAVIALLVDSYKALPIGTALPDAGAFAEVAPTLFLQILRGGLTLALPMMVAML 202 F NGHL +I+LLVD++ LPIG ++ AF + I GL LALP++ +L Sbjct: 137 FLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALT-KAGSLIFLNGLMLALPLITLLL 195 Query: 203 AVNLAFGALAKAAPALNPMQLGLPLTVLLGLFLLSSFASEFAPPVQRMFDTAFDAAREL 261 +NLA G L + AP L+ +G PLT+ +G+ L+++ AP + +F F+ ++ Sbjct: 196 TLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIFNLLADI 254
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 36.6 bits (84), Expect = 5e-04 Identities = 30/116 (25%), Positives = 42/116 (36%), Gaps = 28/116 (24%) Query: 767 AKLLRRKRELEQLVAKRTAELEQDKRDLEAARAEL-SLKATHDELTGLLN-----RAGI- 819 A L K +LE A + +RDL+A+R L+A H +L R + Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLR 350 Query: 820 --LAALREML--LHAEHQGRPLAVVLIDLDHFKLVNDQHGHLAGDAVLAGVGRRMD 871 L A RE L AEHQ KL + +A + R +D Sbjct: 351 RDLDASREAKKQLEAEHQ--------------KLEEQ---NKISEASRQSLRRDLD 389
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 348 bits (895), Expect = e-121 Identities = 105/344 (30%), Positives = 182/344 (52%), Gaps = 2/344 (0%) Query: 8 GERTELPTEKRLREAREQGNIPQSRELSTAAVFGAGVFALMVLARGIGDGAAVWMKTALS 67 GE+TE PT K++R+AR++G + +S+E+ + A+ A LM L+ + + M + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLM--LIP 60 Query: 68 PDPKMRENPMALFGHFGDLLLQLLWVMLPLIGICLAAGLAGPLMMSGLRFSGKAIMPDLT 127 + AL ++LL+ ++ PL+ + +A ++ G SG+AI PD+ Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 128 KLNPANGIKRMWGSNSLAELIKSVLRLLFVGLAASFCISRGLHGLRSLVNQPLEQAIGNG 187 K+NP G KR++ SL E +KS+L+++ + + I L L L +E Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 188 LDFTKSLLFYTAGALVLLAAIDAPYQKWNWLRKLKMTREEIKREMKESEGSPEVKGRIRQ 247 + L+ V+++ D ++ + ++++LKM+++EIKRE KE EGSPE+K + RQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 248 MQMQMSQRQMMEAVPKADVVLMNPTHYAVALKYEGGKMRAPIVVAKGVDEMAFRIREAGE 307 ++ R M E V ++ VV+ NPTH A+ + Y+ G+ P+V K D +R+ E Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 308 QHRVAIVTAPPLARALYREAQIGKEIPVRLYSVVAQVLSYVYQL 351 + V I+ PLARALY +A + IP A+VL ++ + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQ 344
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 4e-05 Identities = 28/178 (15%), Positives = 44/178 (24%), Gaps = 26/178 (14%) Query: 45 NYDEELVQRALETARSDTPASAQHQQAPAQQ--------------APAPQVPAKPAAPVH 90 N + E + ++T TP + Q PAP P++ V Sbjct: 982 NPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA 1041 Query: 91 ALLKPSADAEASQRQRVQRRRRHDRRHG--------AARQPVSVPRQAPVAAPVRTASIP 142 K + Q +R A Q V + +T Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 143 SPAAQALAHAVAVTAAPRQE---HALSAVPEQLFAD-FLTTAPVQRPAVPATAVQAPA 196 A V QE P+Q ++ A R P ++ P Sbjct: 1102 ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 4e-25 Identities = 31/105 (29%), Positives = 50/105 (47%), Gaps = 3/105 (2%) Query: 2 RILIVDDFSTMRRIVKNLLGDLGFTNTAEAEDGNSALAALRAGPFDFVVTDWNMPGMTGI 61 IL+ DD + +R ++ L G+ + + + AG D VVTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DLLRNIRADAKLKHLPVMMVTAEAKREQIIEAAQCGVNGYIIKPF 106 DLL I+ LPV++++A+ I+A++ G Y+ KPF Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 1e-06 Identities = 24/136 (17%), Positives = 44/136 (32%), Gaps = 53/136 (38%) Query: 284 LVRNAIDHGIESPALREATGKPRSGHVRLSAQQEGDYVSIEIQDDGAGIDPERLREIARN 343 LV N I HGI P+ G + L ++ V++E+++ G+ Sbjct: 263 LVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEVENTGSLALKN-------- 306 Query: 344 KGLIDAEAAARLSTDECLHLIFMPGFSTKAEVTDISGRGVGMDVVQSRIRELSG---QIQ 400 G G+ V+ R++ L G QI+ Sbjct: 307 ---------------------------------TKESTGTGLQNVRERLQMLYGTEAQIK 333 Query: 401 IQSELGRGSRFMIRVP 416 + + G+ M+ +P Sbjct: 334 LSEKQGKV-NAMVLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 47/202 (23%), Positives = 74/202 (36%), Gaps = 9/202 (4%) Query: 68 FCIAPFAGYLVDHLPRRRLGMVAVLGLVATALLLLAITQGWLPVEGVWPIYAAISLTGAA 127 F AP G L D RR + +V++ G A ++A +W +Y + G Sbjct: 57 FACAPVLGALSDRFGRRPVLLVSLAG-AAVDYAIMATAPF------LWVLYIGRIVAGIT 109 Query: 128 RSFLSPVYNALFARALPREAFARGASIGSVTFQAGMVIGPALGGVLVGWGGKGLAYGVAA 187 + V A A + AR S F GMV GP LGG++ G+ + AA Sbjct: 110 GA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAA 168 Query: 188 SVAMLAILALALLRVSEPVSEGPRAPIFRSIAEGAQFVLSNQIMLGAMALDMFSVLLGGA 247 + + LL S P + ++ ++ MA+ L+G Sbjct: 169 LNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQV 228 Query: 248 VSMLPA-FIHDILHYGPEGLGI 268 + L F D H+ +GI Sbjct: 229 PAALWVIFGEDRFHWDATTIGI 250
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.6 bits (110), Expect = 1e-07 Identities = 28/175 (16%), Positives = 59/175 (33%), Gaps = 2/175 (1%) Query: 5 KSAKKAVEAAKKSAKPVAKKAATSAAAKPAAKPATKQPAAKKAPAKKAPAKKAAAKPAPA 64 ++ + E +K+ +K V K + + K+ + + + Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 65 SKPTASAAPKAVKPVAKSAAKPAAKKAAPAAAKPAAKPVASKSVPKPATKPAPAKSVPVK 124 ++ T + V+ K+ + + P + +P +PA V Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 125 AEKPAPAPVPKAVPAKPAKPATPSSKNPVPVSKSSAKTPTKTEAP--AKPAATRP 177 ++P A +PAK + + + PV S + + E P PA T+P Sbjct: 1155 IKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQP 1209 Score = 39.3 bits (91), Expect = 2e-05 Identities = 37/240 (15%), Positives = 66/240 (27%), Gaps = 14/240 (5%) Query: 72 APKAVKPVAKSAAKPAAKKAAPAAAKPAAKPVASKSVPKPA--------TKPAPAKSVPV 123 P A P+ A+ PV + P+ +K+V Sbjct: 994 TTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEK 1053 Query: 124 KAEKPAPAPVPKAVPAKPAKPATPSSKNPVPVSKSSAKTPTKTEAPAKPAATRPV---GK 180 + AK AK ++ V++S ++T K AT K Sbjct: 1054 NEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAK 1113 Query: 181 VAVAVTSKPSSSAPKTKYKVVEYKTDEATGRPILPQGYKPAADE--EYMNKLQQEYFRQR 238 V T + + K + +T + P E N + Sbjct: 1114 VETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 239 LQSWRNEMVEESKQTIENLREEVRDIGDEAERATRETENS-LELRARDRARKLISKIDST 297 S E T+ V + + T+ T NS + ++R R+ + + Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233 Score = 38.1 bits (88), Expect = 5e-05 Identities = 37/198 (18%), Positives = 67/198 (33%), Gaps = 6/198 (3%) Query: 3 AKKSAKKAVEAAKKSAKPVAKKAATSAAAKPAAKPATKQPAAKKAPAKKAPAKKAAAKPA 62 AK +K E K +++ V+ K S +P A+PA + ++ A Sbjct: 1112 AKVETEKTQEVPKVTSQ-VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 63 PASKPTASAAPKAVKPVAKSAAKPAAKKAAPAAAKPAAKP-VASKSVPKPATKPAPAKSV 121 PA K T+S + V + + +P V S+S KP + +SV Sbjct: 1171 PA-KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNR--HRRSV 1227 Query: 122 PVKAEKPAPAPVPKAVPAKPAKPATPSSKNPVPVSKSSAKTPTKTEAPAKPAATRPVGKV 181 PA + A S+ +S + AK K A ++ + ++ Sbjct: 1228 RSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGK-AVSQHISQL 1286 Query: 182 AVAVTSKPSSSAPKTKYK 199 + + + T Sbjct: 1287 EMNNEGQYNVWVSNTSMN 1304 Score = 33.1 bits (75), Expect = 0.002 Identities = 39/188 (20%), Positives = 67/188 (35%), Gaps = 18/188 (9%) Query: 101 KPVASKSVPKPATKPAPAKSVPVKAE---KPAPAPVPKAVPAKPAKPATPSSKNPVPVSK 157 + V + ++ P A SVP E + APVP PA P++ ++N SK Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN----SK 1045 Query: 158 SSAKTPTKTEAPAKPAATRPVGKVAVAVTSKPSSSAPKTKYKVVEYKTDEATGRPILPQG 217 +KT K E A + VA +K + A +V + ++ + Sbjct: 1046 QESKTVEKNEQDATETTAQ---NREVAKEAKSNVKANTQTNEVAQSGSETKETQ---TTE 1099 Query: 218 YKPAADEEYMNKLQQEYFRQRLQSWRNEMVEESKQTIENLREEVRDIGDEAERATRETEN 277 K A E K + E + + S+ + + + E E R T N Sbjct: 1100 TKETATVEKEEKAKVETEKT-----QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 278 SLELRARD 285 E +++ Sbjct: 1155 IKEPQSQT 1162
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 5e-05 Identities = 27/97 (27%), Positives = 40/97 (41%), Gaps = 19/97 (19%) Query: 4 TVIVNARLVNEGKEFDADLLIEGGRIAKI----------DSKIVPAPGDTVVDAAGRWVL 53 TVI NA +++ AD+ ++ GRIA I I+ PG V+ G+ V Sbjct: 70 TVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVT 129 Query: 54 PGMIDDQVHFREPGLTHKGDIATESGAAVAGGLTSFM 90 G +D +HF P A+ GLT + Sbjct: 130 AGGMDSHIHFICPQQIE---------EALMSGLTCML 157
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.039 Identities = 9/25 (36%), Positives = 14/25 (56%) Query: 248 LSRIDVKVGDRVEQGQVIAAVGATG 272 + I VK G+ V +G V+ + A G Sbjct: 107 VKEIIVKEGESVRKGDVLLKLTALG 131
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (340), Expect = 6e-41 Identities = 82/252 (32%), Positives = 123/252 (48%), Gaps = 10/252 (3%) Query: 4 RVALVTGGTGGIGTAICKRLADQGHRVASNFRNEEKARHWQQRMQAQGYAFALFRGDVAS 63 ++A +TG GIG A+ + LA QG +A+ N EK ++A+ F DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 64 SEHARALVEDVESSLGPIEVLVNNAGITRDTTFHRMSAEQWHEVINTNLNSVFNVTRPVI 123 S + +E +GPI++LVN AG+ R H +S E+W + N VFN +R V Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 124 EGMRKRGWGRVIQISSINGLKGQYGQANYAAAKAGMHGFTISLARENAAFGVTVNTVSPG 183 + M R G ++ + S + A YA++KA FT L E A + + N VSPG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 184 YVATDM--VMAVPEEVRAKIVA--------DIPTGRLGRPEEIAYAVAFLVAEEAAWITG 233 TDM + E +++ IP +L +P +IA AV FLV+ +A IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 234 SNLDINGGHHMG 245 NL ++GG +G Sbjct: 249 HNLCVDGGATLG 260
>cloacin#Cloacin signature. Length = 551 Score = 29.3 bits (65), Expect = 0.009 Identities = 15/44 (34%), Positives = 16/44 (36%), Gaps = 1/44 (2%) Query: 143 GAGFGRPGGPG-APPNPPGAGGLGSGPMGTGTHGSAGGNHGTTG 185 G G G G G + N P GG GSG G G G Sbjct: 28 GVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS 71
>cloacin#Cloacin signature. Length = 551 Score = 29.7 bits (66), Expect = 0.045 Identities = 16/50 (32%), Positives = 19/50 (38%), Gaps = 5/50 (10%) Query: 339 GGDGTGYTAATSGGMGGIASGGVPGNGGASIGSGGAYSYASWTPSQTPLG 388 GGDG G+ G I G P G GGA + W+ P G Sbjct: 3 GGDGRGHNTGAHSTSGNI--NGGPTGLG---VGGGASDGSGWSSENNPWG 47
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 34.7 bits (79), Expect = 0.001 Identities = 31/153 (20%), Positives = 48/153 (31%), Gaps = 13/153 (8%) Query: 149 AAAPTAAPAPRPLNAQAEAARATAALAASAQRASSVPPPQPSTPPPAPSVPASAMPTVTQ 208 A P P + ++ T A + +S QP T S + +V + Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVT----ESTTVNTGNSVVE 1197 Query: 209 APVPTTIATGVPTPRPATSATTGAPAPTGVAGNTPNRAAGAAAAVPSGAVVAGSSAAAAA 268 P TT AT PT +S N R+ + A + + + A Sbjct: 1198 NPENTTPATTQPTVNSESS---------NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Query: 269 ILNGGSAPMGATSGNAGAIAPNSASGVVAAAGD 301 + + S A +A A A A V A Sbjct: 1249 LCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQ 1281
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.8 bits (67), Expect = 0.012 Identities = 11/50 (22%), Positives = 21/50 (42%), Gaps = 7/50 (14%) Query: 99 LLIGYP-----MAYVIARLPLATRN--VAMMLVVLPSWTSFLIRVYAWIG 141 +LIGY + +V+ +P R + +L+ + F I V + Sbjct: 120 ILIGYSFGAEVIPFVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVT 169
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 103 bits (258), Expect = 8e-26 Identities = 83/407 (20%), Positives = 165/407 (40%), Gaps = 20/407 (4%) Query: 25 WLAVLAGTIGSFMATLDISIVNAALPTIQGEVGASGTEGTWISTAYLVAEIIMIPLTGWF 84 WL +L SF + L+ ++N +LP I + W++TA+++ I + G Sbjct: 18 WLCIL-----SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKL 72 Query: 85 VRTLGLRNFLLICAVMFTAFSVVCGLSTS-LSMMIIGRVGQGLAGGALIPTALTIVATRL 143 LG++ LL ++ SV+ + S S++I+ R QG A + +VA + Sbjct: 73 SDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYI 132 Query: 144 PPSQQTMGTALFGMTVIMGPVIGPLLGGWLTENVSWHYAFFINVPICVGLVALLLLGLKH 203 P + L G V MG +GP +GG + + W Y + +P+ + L+ L Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSY--LLLIPMITIITVPFLMKLLK 190 Query: 204 EKGDWAGLLNADWLGIYGLTAGLGGLTVVLEEGQRERWFESSEINTLSLIALSGFIALVI 263 ++ G D GI ++ G+ + +L F +S + ++++ F+ V Sbjct: 191 KEVRIKGHF--DIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVK 238 Query: 264 SQFRRRPPVIRLSLLLQRSFGAVFIMVMAVGMILFGVMYMIPQFLAVISGYNTEQAGYVL 323 + P + L F + + + G + M+P + + +T + G V+ Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 324 LLSGLPTVLLMPMMPKLLETVDVRILVIAGLICFAAACFVNLSLTADTVGTHFVAGQLLQ 383 + G +V++ + +L + V+ + F + F+ S +T + Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV 358 Query: 384 GCGLALAMMSLNQAAISSVPPELAGDASGLFNAGRNLGGSVGLALIS 430 GL+ ++ SS+ + AG L N L G+A++ Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 94.9 bits (236), Expect = 2e-23 Identities = 52/371 (14%), Positives = 115/371 (30%), Gaps = 83/371 (22%) Query: 81 SVAVAPRVSGYVTKVLVSDNQIVEAGQPLLQIDDRTYQATLQQAEAAIAARQADIVAATA 140 S + P + V +++V + + V G LL++ +A + ++++ + + Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 141 NVSAQESALLQARTQVTAAAASLKFAQAEVKRFAPLAASGADTHEHQES-LQHDLARARA 199 + E L + ++ EV R L T ++Q+ + +L + RA Sbjct: 156 LSRSIELNKLPELK-LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRA 214 Query: 200 QYDAAQAQAKAGESQIQASRAQLE------------------------QAQAGVKQATAD 235 + A+ E+ + +++L+ +A ++ + Sbjct: 215 ERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQ 274 Query: 236 ADQARVAVEDTRLTSRIH------------------------------------------ 253 +Q + + ++ Sbjct: 275 LEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPV 334 Query: 254 -GRVGD-KTVQVGQFLGAGTRTMTIVPQESLYLV-ANFKETQVGLMRPGQPAEIEVDALS 310 +V K G + M IVP++ V A + +G + GQ A I+V+A Sbjct: 335 SVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFP 394 Query: 311 GVK---LHGKVESLSPGTGSQFALLPPENATGNFTKVVQRVPVRIRVLAGDEARKVLVPG 367 + L GKV++++ + G V+ + L G Sbjct: 395 YTRYGYLVGKVKNINLDA-------IEDQRLGLVFNVIISIEENCLSTGNKNIP--LSSG 445 Query: 368 MSVEVTVDTRS 378 M+V + T Sbjct: 446 MAVTAEIKTGM 456
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 32.0 bits (72), Expect = 0.005 Identities = 36/163 (22%), Positives = 57/163 (34%), Gaps = 25/163 (15%) Query: 17 SALRRWLKERSITEVECLVPDITGNARG--KIIPADKFSHDYGTRLPEGIFATTVTGDFP 74 A+ RW++E P+ + A K + P V+GDF Sbjct: 294 EAVDRWIQEN---------PNAAETVEAVFNVAAAAKVAKLAKAAKPG---KAAVSGDFA 341 Query: 75 DDYYALTSPSDSDMHLRPDASTVRMVPWAADPTAQVIHDCYTKDGQPHEL-APRNVLRRV 133 D Y + SDS L +A + + + D +K E+ A N Sbjct: 342 DSYKKKLALSDSARQLYQNAKYREALDIHYEDLIRRKTDGSSKFINGREIDAVTN----- 396 Query: 134 LDAYAQAE--LQPVVAPELEFFLVQKNTDPDFPLLPPAGRSGR 174 DA QA+ + + P + FL QKN + A + G+ Sbjct: 397 -DALIQAKRTISAIDKP--KNFLNQKNRKQIKATIEAANQQGK 436
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-15 Identities = 36/142 (25%), Positives = 60/142 (42%), Gaps = 4/142 (2%) Query: 1029 LEGAHLLLVDDSDINCEVAQRILEGEGAMVTVAHDGEQAVSTLKRAPNLFHLVLMDVQMP 1088 + GA +L+ DD V + L G V + + + LV+ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD--GDLVVTDVVMP 58 Query: 1089 VVDGYEATRRLRQIPALASLPVIALTAGAFRPQQEKALEAGMNGFIAKPFNVEELVTAIR 1148 + ++ R+++ A LPV+ ++A KA E G ++ KPF++ EL+ I Sbjct: 59 DENAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 1149 HFLQPGTRRIPSLPHEAQAHAG 1170 L RR L ++Q Sbjct: 117 RALAEPKRRPSKLEDDSQDGMP 138 Score = 63.7 bits (155), Expect = 3e-12 Identities = 29/142 (20%), Positives = 51/142 (35%), Gaps = 22/142 (15%) Query: 891 PRVLIADDHDAALNNLVRIATELGWRVDAVASGQAALQAIEHAAEPYDIFLLDWRMPDID 950 +L+ADD A L + + G+ V ++ + I AA D+ + D MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWI--AAGDGDLVVTDVVMPDEN 61 Query: 951 GVAIAREIRARATPGPH-PVIVM---------VTAYERRLLEQHPEQQDLDAVMTKPVTG 1000 + I+ P PV+VM + A E+ + P+ DL ++ Sbjct: 62 AFDLLPRIKKA---RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI------ 112 Query: 1001 AALHRLVEQLLEERPGARPATP 1022 + + RP Sbjct: 113 -GIIGRALAEPKRRPSKLEDDS 133
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 2e-13 Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 4/145 (2%) Query: 1 MPSRPLLCVDDESSNLATLRQLL-RDDFALVFAKSGGEALDAVSRHAPKLILLDVELPDM 59 M +L DD+++ L Q L R + + + ++ L++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 60 DGYAVARALKQQPSSNAIPILFVTSRNSEHDERLGLEAGAADYVSKPYSPALLKARIGTQ 119 + + + +K+ +P+L ++++N+ E GA DY+ KP+ L IG Sbjct: 61 NAFDLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 120 LKLAENARLAQQYRDAIHLLGTAGQ 144 L R ++ D+ + G+ Sbjct: 119 LAE-PKRRPSKLEDDSQDGMPLVGR 142
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 113 bits (285), Expect = 2e-29 Identities = 79/411 (19%), Positives = 163/411 (39%), Gaps = 17/411 (4%) Query: 23 LILACAI-FMEQMDATVLATALPTLARDFGVAAPAMSIAMTSYLLALAVLIPASGAIADR 81 LI C + F ++ VL +LP +A DF + + T+++L ++ G ++D+ Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 82 FGLRRVFGASIWVFVGGSILCSLADS-LPTMVAARVLQGAGGAMMAPLGRLILLRTVERR 140 G++R+ I + GS++ + S ++ AR +QGAG A L +++ R + + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 141 HLVSAMAWTLVPAFIGPMLGPPLGGFFVSYLDWRWIFYINVPIGIAGFLLVRRFIPEIPT 200 + A +G +GP +GG Y+ W ++ I + I I + + + + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKKEVR 194 Query: 201 ESGPARFDLRGFVLCGTALGCLLFGLEMVSQQNGIGTASWLLAIGGSAALG-YLWHARHH 259 G FD++G +L + + + S I + ++ H R Sbjct: 195 IKGH--FDIKGIILMSVGIVFFML---------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 260 PAPLLDLSLLRIDSFRLSVIGGALMRITQGAHPFLLPLLFQIGFGMSAAHSGRLILATAL 319 P +D L + F + V+ G ++ T ++P + + +S A G +I+ Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 320 GALLMRS-ITPQLLRRFGYRNSLIGNGVLASLGYMVCALFRPDWPPALMFGLLLCCGAFM 378 ++++ I L+ R G L S+ ++ + + ++ G + Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GL 362 Query: 379 SFQFAAYNTIAYENVPAACMSRASSLYTTLQQLMLSVGVCAGAMILKLAML 429 SF +TI ++ SL L G+ +L + +L Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLL 413
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.6 bits (136), Expect = 5e-12 Identities = 33/217 (15%), Positives = 72/217 (33%), Gaps = 15/217 (6%) Query: 2 IPRSHRAARRSDCDRRIHAAVHALLAERGMR-LSMDAVAERAGCSKQTLYSYYGCKENLL 60 + R + + + A+ L +++G+ S+ +A+ AG ++ +Y ++ K +L Sbjct: 1 MARKTKQEAQETRQHILDVALR-LFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 RDVLQDHVR----LAAGPLGTVSGDLHADLLAFALAHLDRLNNPDV---LQTCRLVEAQS 113 ++ + L GD + L + L+ + L + + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 114 HRFPDQSQQIFHDGVVGMQQRLAHRFEQAIDAGQLRHD-DPHFMAELLLSMIVGLDFDRQ 172 QQ + + R+ + I+A L D A ++ I GL + Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 173 RFQVPHRAGLPARQRWAQFAVDTFLRAFAPAPAAPTP 209 ++ A+ V L + P P Sbjct: 180 F-----APQSFDLKKEARDYVAILLEMYLLCPTLRNP 211
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.2 bits (94), Expect = 1e-05 Identities = 17/108 (15%), Positives = 37/108 (34%) Query: 59 RSADVRARVDGVVLKRLYTEGANVTEGQPLFQIDPSQLKATLLQAQGQLAAAEATYTNAK 118 RS +++ + +V + + EG +V +G L ++ +A L+ Q L A T + Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 119 IAATRARSLAPQQYVSRADIDTAEANERSSGANVQQARGAVEAARIQL 166 I + + + +E + + Q Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK 202 Score = 32.1 bits (73), Expect = 0.004 Identities = 13/51 (25%), Positives = 24/51 (47%), Gaps = 4/51 (7%) Query: 59 RSADVRARVDGVVLK-RLYTEGANVTEGQPLFQIDPSQLKATLLQAQGQLA 108 +++ +RA V V + +++TEG VT + L I P L+ + Sbjct: 326 QASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPED---DTLEVTALVQ 373
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1081 bits (2797), Expect = 0.0 Identities = 516/1038 (49%), Positives = 705/1038 (67%), Gaps = 17/1038 (1%) Query: 1 MPKFFIEHPVFAWVVAILISLAGVISILNLGIESYPTIAPPQVTVTANFPGASADTAEKA 60 M FFI P+FAWV+AI++ +AG ++IL L + YPTIAPP V+V+AN+PGA A T + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQQLTGIDHLLYFNSSSAANGRVTITLTFETGTDADIAQVQVQNKVSLATPRLPS 120 VTQVIEQ + GID+L+Y +S+S + G VTITLTF++GTD DIAQVQVQNK+ LATP LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVTQQGVVVAKANAGFLMVAALRSDNPSINRDALNDIVGSRVLEQISRVPGVGSTNQFGA 180 EV QQG+ V K+++ +LMVA SDNP +D ++D V S V + +SR+ GVG FGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 EYAMNIWLNPEKLQGYNLSATQVLTAVRNQNVQFAAGSVGADPTPEGISFTATVSAEGRF 240 +YAM IWL+ + L Y L+ V+ ++ QN Q AAG +G P G A++ A+ RF Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 SSPEQFENIILRTDNNGATVRLKDVARVTVGPSNYGFDTQYNGKPTGAFGIQLLPGANAL 300 +PE+F + LR +++G+ VRLKDVARV +G NY + NGKP GI+L GANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 NVSEAVGAKLDELQPTFPQGVTWFAPYESTTFVRISIEEVIHTLVEAIVLVFLVMLLFLQ 360 + ++A+ AKL ELQP FPQG+ PY++T FV++SI EV+ TL EAI+LVFLVM LFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATVIPTLVIPVALLGTFFGMYMIGFTINQLTLFAMVLAIGIVVDDAIVVIENVERIM 420 N RAT+IPT+ +PV LLGTF + G++IN LT+F MVLAIG++VDDAIVV+ENVER+M Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 SEEHLEPKAATQKAMTQITGAVVAITVVLAAVFIPSSLQPGASGAIYKQFALTIAMSMGF 480 E+ L PK AT+K+M+QI GA+V I +VL+AVFIP + G++GAIY+QF++TI +M Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SAFLALSFTPALCGAFLK---STHSTKKNWVYRTFDKYYDKLAHRYVGVVGHTLKRSPPW 537 S +AL TPALC LK + H K + F+ +D + Y VG L + + Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 538 MIAFVALLVLCGFLFTRMPGSFLPEEDQGFAVAIVQLPPGATKIRTNEAFAQMRAVLEKQ 597 ++ + ++ LF R+P SFLPEEDQG + ++QLP GAT+ RT + Q+ K Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 598 PA--VEGMLQIAGFSFLGSGENVGMGFIRLKPWEERDV---TAEQLIQQLNGAFYGIKGA 652 VE + + GFSF G +N GM F+ LKPWEER+ +AE +I + I+ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 653 QIFVVNLPTVQGLGQFGGFDMWLQDRSGAGQEALINARNIVLGKAAEKQDTLVGVRPNGL 712 + N+P + LG GFD L D++G G +AL ARN +LG AA+ +LV VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 713 ENSPQLQLHVDRVQAQSMGLDVSDIYSSIQLMLAPVYVNDYFAEGRIKRVNMRADDQFRA 772 E++ Q +L VD+ +AQ++G+ +SDI +I L YVND+ GR+K++ ++AD +FR Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 773 GPESLRNFFTPSATATGTDGQPAMIPLSNVVKAEWNYASPALNRYNGYSAVNIVGNPAPG 832 PE + + SA +G+ M+P S + W Y SP L RYNG ++ I G APG Sbjct: 781 LPEDVDKLYVRSA-----NGE--MVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPG 833 Query: 833 GSSGQAMSAMEDIVNNDLPPGFGFDWSGMSYQEIIAGNAATLLLALSVVVVFLCLAALYE 892 SSG AM+ ME++ + LP G G+DW+GMSYQE ++GN A L+A+S VVVFLCLAALYE Sbjct: 834 TSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYE 892 Query: 893 SWSIPVAVLLVVPIGVLGAITFSMLRGLPNDLYFKIGMITVIGLAAKNAILIVEFAVE-Q 951 SWSIPV+V+LVVP+G++G + + L ND+YF +G++T IGL+AKNAILIVEFA + Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLM 952 Query: 952 RAAGKTLREATLEAAHLRFRPILMTSFAFILGVLPLAISTGAGANSRHSIGTGVIGGMVF 1011 GK + EATL A +R RPILMTS AFILGVLPLAIS GAG+ +++++G GV+GGMV Sbjct: 953 EKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012 Query: 1012 ATVLGVIFIPLFFVVVRR 1029 AT+L + F+P+FFVV+RR Sbjct: 1013 ATLLAIFFVPVFFVVIRR 1030
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 112 bits (282), Expect = 1e-31 Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 22/170 (12%) Query: 68 ERRQHAMVGAGIGALSGAAIGQYQDRQERALRERTANTGIEVQRQGDNITLNLPDGITFD 127 R + M+ G+ G + + EVQ + L + F+ Sbjct: 176 TRPDNGMLSLGVSYRFGQG-------EAAPVVAPAPAPAPEVQTK----HFTLKSDVLFN 224 Query: 128 FGKSALKPQFYSALNGVASTLREYN--QTMVEVVGHTDSVGSDAVNQRLSEERAGAVAQY 185 F K+ LKP+ +AL+ + S L + V V+G+TD +GSDA NQ LSE RA +V Y Sbjct: 225 FNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDY 284 Query: 186 LTAQGVQRERMETMGAGKRYPIADNSTDAGR---------AQNRRVEIRL 226 L ++G+ +++ G G+ P+ N+ D + A +RRVEI + Sbjct: 285 LISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.8 bits (59), Expect = 0.011 Identities = 11/53 (20%), Positives = 21/53 (39%), Gaps = 9/53 (16%) Query: 36 EIMTITHTQVPDAVSGRGIAAALVEDALAFARQ---HGLKV------VPACRY 79 I V +G+ AL+ A+ +A++ GL + + AC + Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHF 140
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 37.5 bits (86), Expect = 2e-04 Identities = 36/195 (18%), Positives = 63/195 (32%), Gaps = 13/195 (6%) Query: 410 VMSGGGSSRVDYTINGGNAVPGITPTTWPGPVIIHPSSPLQALRAALPNVQIDYLDGTDR 469 + G++ + I+ AV G + P + + +S + R A D Sbjct: 268 IQVAQGAASLAQAISDAIAVLGRVLASAPSVMAVGFASLTYSSRTAEQWQDQT----PDS 323 Query: 470 AAAARAAKAADVAIVFATQW-----AAESVDLPDMRLPDNQDALIETVA-KANPKTTVVL 523 A AA + + + A+ +VDLP MRL + T++ + +V Sbjct: 324 VRYALGMDAAKLGLPPSVNLNAVAKASGTVDLP-MRLTNEARGNTTTLSVVSTDGVSVPK 382 Query: 524 ETNGPVRMPWAERVPAVLQAWYPGIGGGEAIANLLTGAVNPSGHLPVTWPVDESQLPRPS 583 PVRM + + P L +P G+ + P P Sbjct: 383 AV--PVRMAAYNATTGLYEVTVPSTTAEAPPLILTWTPASPPGNQNPSSTTPVVPKPVPV 440 Query: 584 IPGLGFKPAKPGEDS 598 G P K ++ Sbjct: 441 YEGATLTPVKATPET 455
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 118 bits (296), Expect = 9e-31 Identities = 96/402 (23%), Positives = 163/402 (40%), Gaps = 30/402 (7%) Query: 33 LAMASFMQVLDTTIANVSLPTIAGNLGASSQQATWVITSFAVSTAIALPLTGWLSRRFGE 92 L + SF VL+ + NVSLP IA + WV T+F ++ +I + G LS + G Sbjct: 19 LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGI 78 Query: 93 TRLFVWSTLAFTIASLLCGLAQSM-GMLVVARALQGFVAGPMYPITQSLLVSIY-PREKR 150 RL ++ + S++ + S +L++AR +QG +P ++V+ Y P+E R Sbjct: 79 KRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVARYIPKENR 137 Query: 151 GQALALLAMITVVAPIAGPILGGWITDNYSWEWIFLINVPLGIIASSIVGSQLRH--RPE 208 G+A L+ I + GP +GG I W +L+ +P + + I L + E Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIP---MITIITVPFLMKLLKKE 192 Query: 209 QLEKPRMDYIGLILLVVGVGALQLVLDLGNDEDWFSSDKIVVLACIAAVALVVFVIWELT 268 K D G+IL+ VG+ L F++ + ++ ++ ++FV Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRK 242 Query: 269 DKDPIVDLKLFRHRNFRAGTLAMVVAYAAFFSVSLLIPQWLQRDMGYTAIRAGLATAPIG 328 DP VD L ++ F G L + + ++P ++ + G G Sbjct: 243 VTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 329 ILPVLMT-PFVGKYALRFDLRMLATIAFIFMS---FTSFFRSNFNLQVDFGHVATIQLVM 384 + V++ G R + I F+S T+ F TI +V Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-----FMTIIIVF 357 Query: 385 GVGVALFFMPVLQ-ILLSDLDGREIAAGSGLATFLRTLGGSF 425 +G F V+ I+ S L +E AG L F L Sbjct: 358 VLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 76.0 bits (187), Expect = 4e-17 Identities = 47/293 (16%), Positives = 92/293 (31%), Gaps = 36/293 (12%) Query: 82 VERGQLLVQLDPADTEVALQQAEANLAKTVRQVRGLYRTVEGAQAELSAREVTLRSARSD 141 V R L++ + + Q E NL K + A ++ E R +S Sbjct: 184 VLRLTSLIKEQFSTWQNQKYQKELNLDKKRAER-------LTVLARINRYENLSRVEKSR 236 Query: 142 FARRKDLAATGAIS--------------NEELAHARDELAAAEAAVSGSRESLERNRAL- 186 L AI+ EL + +L E+ + ++E + L Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF 296 Query: 187 ---VDDSAVANQPDVQTAAAQLRQAYLNHARTGVVAPVSGYVARRSAQ-VGQRVQPGSVL 242 + D ++ +L + + + APVS V + G V L Sbjct: 297 KNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL 356 Query: 243 MAVVPLEQV-WVEANFKETQLKHMRLGQEVELHSDLYGGGVSYTGRIQSLGLGTGSAFSL 301 M +VP + V A + + + +GQ + + + + G + G Sbjct: 357 MVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPY--TRYGYL------VGK-VKN 407 Query: 302 LPAQNASGNWIKIVQRVPVRIAVDSKQLASNPLRIGLSMKVDVNLHDQQGSVL 354 + + +V V + I + + + + M V + SV+ Sbjct: 408 INLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVI 460
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.008 Identities = 29/187 (15%), Positives = 62/187 (33%), Gaps = 20/187 (10%) Query: 81 AQLDALIAEGLQHSPSLAAADARLHQAQARIGSAQAERG--PSLSVSGGYTGLQLPESMV 138 +L AL AE + ARL Q + +I S E P L + + E V Sbjct: 125 LKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 139 GEELGGSYGGSAQVVLDFRYGVDLWGGKRSAWEAAVDQAHAAEVDAQAARLNLSSAIAEG 198 L + W ++ E +D+ A + A + Sbjct: 185 ----------LRLTSL-IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 199 YAQLAYAWSLHDLANDELSRAQKTLELTRQRRSAGIDSELQVRQAQARVPAAQQQLQSAQ 258 ++L L + + LE + +++ ++R ++++ + ++ SA+ Sbjct: 234 KSRLD---DFSSLLHKQAIAKHAVLEQENKY----VEAVNELRVYKSQLEQIESEILSAK 286 Query: 259 QQIDEAR 265 ++ Sbjct: 287 EEYQLVT 293
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 3e-15 Identities = 30/119 (25%), Positives = 48/119 (40%), Gaps = 2/119 (1%) Query: 11 PRLLLVEDDPISRGFLQAVLESLPATVDCADSLSSALDRARERRHDLWLIDVNLPDGTGS 70 +L+ +DD R L L V + ++ DL + DV +PD Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 GLLRALRLLHPDVPALAHTADAT-MSMQNSLQSDGFLEMLVKPLTSERLLQAVRRGLAR 128 LL ++ PD+P L +A T M+ + + G + L KP L+ + R LA Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEK-GAYDYLPKPFDLTELIGIIGRALAE 121
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 33.3 bits (76), Expect = 0.001 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 10/70 (14%) Query: 62 LVDTPGLHREQKRAMNRVMNRAARGSLEGVDAAVLVIEAGRWDEEDT-LAFRVLSDAGVP 120 ++DTPG H + + R SL +D A+L+I A + T + F L G+P Sbjct: 72 IIDTPG-HMDFLAEVYR--------SLSVLDGAILLISAKDGVQAQTRILFHALRKMGIP 122 Query: 121 VVLVVNKVDR 130 + +NK+D+ Sbjct: 123 TIFFINKIDQ 132
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 146 bits (370), Expect = 2e-39 Identities = 94/453 (20%), Positives = 180/453 (39%), Gaps = 85/453 (18%) Query: 8 NIRNFSIIAHVDHGKSTLADRIIQLCGG---LQAREMEAQVLDSNPIERERGITIKAQSV 64 I N ++AHVD GK+TL + ++ G L + + D+ +ER+RGITI+ Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 65 SLPYTAKDGQTYHLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAAQGVEAQSVANCYTA 124 S + + +N IDTPGH+DF EV RSL+ +GA+L++ A GV+AQ+ + Sbjct: 62 SFQW-----ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 125 VEQGLEVVPVLNK-----IDLP----------TADVDRAKA----------------EIE 153 + G+ + +NK IDL +A++ + + + Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 154 AVIG--------------IDAEDAVAV----------------SAKTGLNIDLVLEAIVH 183 VI ++A + SAK + ID ++E I + Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITN 236 Query: 184 RIPPPKPRDTDKLQALIIDSWFDNYLGVVLLVRVMQGEIKPGSKILVMSTGRTHLVDKVG 243 + R +L + + + +R+ G + + + + + + Sbjct: 237 KFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYT 296 Query: 244 VFTPKRKELPALGAGEVGWINASIKDVHGAPVGDTLTLAGDPAPHALPGFQEMQPRVFAG 303 + ++ +GE+ + + + +GDT L + P + Sbjct: 297 SINGELCKIDKAYSGEIVILQNEFLKL-NSVLGDTKLLPQRERI------ENPLPLLQTT 349 Query: 304 LFPVDAEDYPDLREALDKLRLNDAALRFE--PESSEAMGFGFRCGFLGMLHMEIVQERLE 361 + P + L +AL ++ +D LR+ + E + FLG + ME+ L+ Sbjct: 350 VEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEII-----LSFLGKVQMEVTCALLQ 404 Query: 362 REYNLDLISTAPTVVY--EVLKTDGTVINMDNP 392 +Y++++ PTV+Y LK I+++ P Sbjct: 405 EKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP 437 Score = 33.7 bits (77), Expect = 0.003 Identities = 21/103 (20%), Positives = 38/103 (36%), Gaps = 18/103 (17%) Query: 367 DLISTAPTVVYEVLKTDGTVINMDNPAKLPQLNLVQEIREPIIRANVLTPEEYIGNIIKL 426 D AP V+ +VLK GT E+ EP + + P+EY+ Sbjct: 515 DFRMLAPIVLEQVLKKAGT-----------------ELLEPYLSFKIYAPQEYLSRAYTD 557 Query: 427 CEEKRGTQIGINYLGSQVQISYELPMAEVVLDFFDKLKSVSRG 469 + + ++V +S E+P + ++ L + G Sbjct: 558 APKYCANIVDTQLKNNEVILSGEIPARC-IQEYRSDLTFFTNG 599
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 73.1 bits (179), Expect = 3e-16 Identities = 33/163 (20%), Positives = 58/163 (35%), Gaps = 28/163 (17%) Query: 133 AGKSMGSGFIISADGYVLTNHHVVDGASEVTVKLTDRR-----------EFKA-KVVGSD 180 G + SG ++ +LTN HVVD L F A ++ Sbjct: 99 TGTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYS 157 Query: 181 EQYDVALLKIEA--------KGLPTVRLGDSNTLKPGQWVVAIGSPFGLDHSVTAGIVSA 232 + D+A++K + + + ++ + Q + G P V+ Sbjct: 158 GEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VAT 210 Query: 233 TGRSNPYADQRYVPFIQTDVAINQGNSGGPLLNTRGEVVGINS 275 S +Q D++ GNSG P+ N + EV+GI+ Sbjct: 211 MWESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 33.1 bits (75), Expect = 0.001 Identities = 23/90 (25%), Positives = 28/90 (31%), Gaps = 18/90 (20%) Query: 171 AALAAAVPAAALASTRRGAATRNQQVARSAAARQQQAPSRLVAAAAPAPTGTASAVAATP 230 AAL A P AA A A T N +A A T V TP Sbjct: 13 AALLAVAPIAATAMPVNAATTIN------------------ADSAINANTNAKYDVDVTP 54 Query: 231 SNPFTHPDTTLQARPWPRAALSGAGESSLN 260 S P +L+G+ +S N Sbjct: 55 SISAIAAVAKSDTMPAIPGSLTGSISASYN 84
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 2e-14 Identities = 23/127 (18%), Positives = 51/127 (40%), Gaps = 4/127 (3%) Query: 1063 LLLVEDDATVAQVIVGLLQARGHHVTHALHGLAALAEVSTRSFDAGLCDLDLPGLDGAAL 1122 +L+ +DDA + V+ L G+ V + ++ D + D+ +P + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 1123 VAQLRARGVRFPIVAVTARADTDAEPQAMAAGCNGFLRKPV----TGELLAQALARVLAD 1178 + +++ P++ ++A+ +A G +L KP ++ +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 1179 VDDGQRD 1185 + D Sbjct: 126 PSKLEDD 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 3e-13 Identities = 24/116 (20%), Positives = 53/116 (45%), Gaps = 2/116 (1%) Query: 2282 QVPLVMVVDDSLTMRKVTSRVLERHNLDVSTARDGVEALELLEERVPDLMLLDIEMPRMD 2341 ++V DD +R V ++ L R DV + + DL++ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 2342 GYELATAMRADPRFKAVPIVMITSRSGEKHRQRAFEIGVQRYLGKPYQELDLMRNV 2397 ++L ++ +P++++++++ +A E G YL KP+ +L+ + Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGII 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.0 bits (218), Expect = 1e-23 Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 2/116 (1%) Query: 2 ARIILIEDSPTDRAVFSQWLEKAGHTVVATDNAEEGLELVRSQAPDLVLMDVVLPGMSGF 61 A I++ +D R V +Q L +AG+ V T NA + + DLV+ DVV+P + F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRALARDQATKDIPVLLVSTKGMETDRAWGLRQGASDYIVKPPREDDLIARIRQ 117 + + + D+PVL++S + +GA DY+ KP +LI I + Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 2e-18 Identities = 28/115 (24%), Positives = 49/115 (42%), Gaps = 2/115 (1%) Query: 15 KVMVIDDSKTIRRTAETLLKREGCEVVTATDGFEALAKIADQQPQIIFVDIMMPRLDGYQ 74 ++V DD IR L R G +V ++ IA ++ D++MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 75 TCALIKGNQLFKSTPVIMLSSKDGLFDKARGRIVGSEQYLTKPFTREELLSAIRT 129 IK + PV+++S+++ + G+ YL KPF EL+ I Sbjct: 65 LLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 130 bits (328), Expect = 9e-39 Identities = 40/262 (15%), Positives = 86/262 (32%), Gaps = 37/262 (14%) Query: 11 MDDGRRLMMTLVISLLLHGVLILGVGFAVSEDAPLVPTLDVIFSQTSTPLTPKQADFLAQ 70 +D RR ++S+ +HG ++ G+ + +P P P +A Sbjct: 8 LDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPA----------PAQPISVTMVAP 57 Query: 71 ANQQGGGDHATAQRPRDSQPGVVPQDRTGLAPQAQRATSVNAPEPTQTRVVTSRRGEQAV 130 A P P+ P+ + P + Sbjct: 58 A--------DLEPPQAVQPP---PEPVVEPEPEPEPIPEPPKEAPVV------------I 94 Query: 131 PTPQPNPQTDPLTPAEAQRIQRDAEMARLAAEVHLRSEQYAKRPNRKFVSASTREYAYAN 190 P+P P+ P + ++ +RD + + A+ + +A+++ Sbjct: 95 EKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA 154 Query: 191 YLRAWVDRAERVGNLNYPDDARRRRLGGKVVISVGVRRDGSVESSRVLVSSGVPLLDDAA 250 + R YP A+ R+ G+V + V DG V++ ++L + + + Sbjct: 155 SGPRALSRN----QPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREV 210 Query: 251 LRVVQLAQPFPPLPKTKDDVDI 272 ++ + P P + V+I Sbjct: 211 KNAMRRWRYEPGKPGSGIVVNI 232
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.5 bits (113), Expect = 1e-09 Identities = 14/82 (17%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 4 RVLLVEDESLVAMLLEDCLAELGYEVAATVADVDAALQAVQAGNLDLALLDINLGGTLSF 63 +L+ +D++ + +L L+ GY+V ++ + + AG+ DL + D+ + +F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDV-RITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 64 PIAEELDAR--GVPYIFVTGYA 83 + + +P + ++ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQN 85
>PF06580#Sensor histidine kinase Length = 349 Score = 35.2 bits (81), Expect = 2e-04 Identities = 40/207 (19%), Positives = 70/207 (33%), Gaps = 20/207 (9%) Query: 126 EHKQHEQHLQLLINELN-HRVKNSLVMVQSLARQSFTNAGSLGDAQEKLDARLLALSRAH 184 E L L ++N H + N+L +++L + ++ L L R Sbjct: 155 ASMAQEAQLMALKAQINPHFMFNALNNIRALILED-------PTKAREMLTSLSELMRYS 207 Query: 185 DTLTRENWVS-ADILELTRDAAALYESHDGQRFTLQGDSCRLDP--RRALALSMALHELC 241 + VS AD L + L R + ++P M + L Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ---INPAIMDVQVPPMLVQTLV 264 Query: 242 TNALKHGALSLPAGNVLVSWERSTRGEQELLELIWREAGGPPVQP-PTRKGFGTRLLERG 300 N +KHG LP G ++ + + L G ++ G G + + Sbjct: 265 ENGIKHGIAQLPQGGKIL---LKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRER 321 Query: 301 LK--HDLEGEVELSFDPAGVCFRVSIP 325 L+ + E +++LS V V IP Sbjct: 322 LQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.001 Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 7/88 (7%) Query: 30 RVAVLEQQQANSQANNDL---LNQLQQARSDLQALRSTVEQLQHD--NEQLKQ--QSKDQ 82 + AVLEQ+ +A N+L +QL+Q S++ + + + + NE L + Q+ D Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 83 YLDLDGRLNRLEGAGGATPPLPPATGNV 110 L L + E A+ P + V Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKV 338
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 106 bits (266), Expect = 3e-30 Identities = 35/112 (31%), Positives = 51/112 (45%), Gaps = 11/112 (9%) Query: 67 VYFDLDQDSLKPEFQAIMACHAKYLR--DRPSSRITLQGNADERGSREYNMGLGERRGNA 124 V F+ ++ +LKPE QA + L D + + G D GS YN GL ERR + Sbjct: 221 VLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQS 280 Query: 125 VSSSLQAAGGSASQLTVVSYGEERPVCTESNE---------SCWSQNRRVEI 167 V L + G A +++ GE PV + + C + +RRVEI Sbjct: 281 VVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEI 332
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.1 bits (145), Expect = 6e-12 Identities = 46/280 (16%), Positives = 86/280 (30%), Gaps = 35/280 (12%) Query: 39 LWSPE-----RSVEPAAGDPSMEASLDVSAAEARVARQALKATPVETPPPPAPLPEPAPE 93 L++PE ++V+ DV + + A PP PA E Sbjct: 980 LYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 94 DSVPPPQ--PIPEPRPQDA--PTPQQAQAQERVAQPDKVDQERVDALAISAEKAKQEQEA 149 + Q E QDA T Q + K + V A + E A+ E Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREV-------AKEAKSNVKANTQTNEVAQSGSET 1092 Query: 150 KRRQEQIDLTERKRQEEAEQKLRLAKQQEEAD------AKKKQAAAQQAAEEAERQKKIA 203 K Q ++E + K+ K QE K++Q+ Q E R+ Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPT 1152 Query: 204 DIRRQRAQADKEMALAEQKLRQVAAARAQQASAAAATSAQPTAGQGGTSTDLSAKYAAAI 263 ++ A EQ ++ ++ Q + + + + + +T + Sbjct: 1153 VNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVN 1212 Query: 264 QQ-------------KVLAQWVRPPSVPPGQKCTINIRQL 290 + + + V P + + T+ + L Sbjct: 1213 SESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDL 1252 Score = 36.2 bits (83), Expect = 2e-04 Identities = 33/217 (15%), Positives = 63/217 (29%), Gaps = 16/217 (7%) Query: 47 EPAAGDPSMEASLDVSAAE-----ARVARQALKATPVETPPPPAPLPEPAPEDSVPPPQP 101 + + EA +V A A+ + + ET E + V + Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV--EKEEKAKVETEKT 1119 Query: 102 IPEPRPQDAPTPQQAQAQERVAQPDKVDQERVDALAISAEKAKQEQEAKRRQEQIDLTER 161 P+ +P+Q Q++ Q + +E + I +++ A Q + + Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEP-ARENDPTVNIKEPQSQTNTTADTEQPAKETSSN 1178 Query: 162 KRQEEAEQKLRLAKQQEEADAKKKQAAAQQAAEEAERQKKIADIRRQRAQADKEMALAEQ 221 Q E + + A Q +E K + R+ + + Sbjct: 1179 VEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVR-------SVP 1231 Query: 222 KLRQVAAARAQQASAAAATSAQPTAGQGGTSTDLSAK 258 + A + S A T S D AK Sbjct: 1232 HNVEPATTSSNDRSTVALCDLTSTNTNAVLS-DARAK 1267
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 28.4 bits (63), Expect = 0.045 Identities = 20/72 (27%), Positives = 28/72 (38%), Gaps = 17/72 (23%) Query: 17 AADASIRPKRLADYLGQQPVRE----QMEIYIQAAKAR-----------GEAMD--HVLI 59 A A +AD L Q E Q E +I++ K R +D H+L+ Sbjct: 131 LAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLV 190 Query: 60 FGPPGLGKTTLS 71 FGP L + L Sbjct: 191 FGPNSLFQEILD 202
>PF04183#IucA / IucC family Length = 580 Score = 147 bits (372), Expect = 6e-40 Identities = 83/361 (22%), Positives = 122/361 (33%), Gaps = 42/361 (11%) Query: 139 AQAPALRNALHHPDAAERAYRCDQLASYRD-HPFYPTARAKSGLDAAELRHYAPEFAPTF 197 Q R L D D+L HP + + + G L YAPE+A TF Sbjct: 107 LQLLKARRGLSASDLINLNA--DRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTF 164 Query: 198 ALRWLAIPQALAQCTSA---PPAALWP---------QFENLGLPPELTATHLAWPVHPMV 245 L WLA+ + L +F + L L PVHP Sbjct: 165 RLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQ 224 Query: 246 WERLEQEGFA--LPEG-VHRAPSAWLDVRPTLSVRTLVPLQHPH-LHLKLPIPMRTLGAL 301 W++ F EG + S+RTL L +KLP+ + Sbjct: 225 WQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSC- 283 Query: 302 NLRLIKPSTLYDGHWMERALRHIDAVDPALQDRCVFV-DESHGGHV-------------G 347 R I + G R L+ + A D L + E G+V Sbjct: 284 -YRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYR 342 Query: 348 QTRHLAYLVRRYPAL---DDATLVPVAALCAPMPDGRPMAIHLAERFAHGDVLRWWRDYT 404 L + R P D + V +A L + +P+A +R D W Sbjct: 343 YQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGL-DAETWLTQLF 401 Query: 405 ELLLAVHLRLWLRYGVALEANQQNSVMVYADGQATRLLMKDN-DAARIALPQLREA--LP 461 +++ L RYGVAL A+ QN + +G R+L+KD R+ + E LP Sbjct: 402 RVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLP 461 Query: 462 E 462 + Sbjct: 462 Q 462
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 60.2 bits (146), Expect = 4e-12 Identities = 56/172 (32%), Positives = 72/172 (41%), Gaps = 4/172 (2%) Query: 20 LGMPLFLPQVLAELAPSA-AVGWSGVLYVLPTLCTALTASTWGRWADRNGRKRSLLRAQL 78 L MP+ LP +L +L S G+L L L A G +DR GR+ LL + Sbjct: 23 LIMPV-LPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLA 81 Query: 79 GLALGFAIAGFAPSLTWLVIGLIVQGTCGGSLAAANAYLASQPQAGPLARALDWTQYSAR 138 G A+ +AI AP L L IG IV G G + A A AY+A AR + Sbjct: 82 GAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFG 141 Query: 139 LAMVSAPALLGLALALGPAQSLYRALALLPLIAFALT-WRLPADQPAAREPA 189 MV+ P L GL P + A A L + F + LP R P Sbjct: 142 FGMVAGPVLGGLMGGFSPHAPFFAA-AALNGLNFLTGCFLLPESHKGERRPL 192 Score = 33.6 bits (77), Expect = 0.001 Identities = 22/64 (34%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 323 LAHIASGHSAGRLFGRFDACGKWAGVFAGAAAGALAQASGPATPFLAAALAAAAAALTVL 382 +A I G R FG AC G+ AG G L P PF AAA LT Sbjct: 120 IADITDGDERARHFGFMSACFG-FGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 383 VRFP 386 P Sbjct: 179 FLLP 182
>PF04183#IucA / IucC family Length = 580 Score = 289 bits (740), Expect = 3e-92 Identities = 103/511 (20%), Positives = 177/511 (34%), Gaps = 47/511 (9%) Query: 100 DAQALARCLLQALGSAQAINPELLAQSANSVAVT----AALL--RQAQVTAATGEAMIDA 153 D LA+ LL L +++ +A+ + T LL R+ + D Sbjct: 69 DEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNADR 128 Query: 154 EQSMLWGHALHPTPKSREGVDLDQVLACAPEARAAFQLFWF-------------RIDPRL 200 Q +L GH K R G + + APE F+L W +D Sbjct: 129 LQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQ 188 Query: 201 LRTQGRDVRATLR-----QLCGSDDLY---PCHPWEAQRLLDAPLLRSLQARGLIASVGP 252 L T D + R Q G D + P HPW+ Q+ + + A G + S+G Sbjct: 189 LLTAAMDPQEFARFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADF-AEGRMVSLGE 247 Query: 253 LGDALRPTSSVRTLYHPE--LAYFLKCSVHVRLTNCVRKNAWYELESAVALTELLAPSWR 310 GD S+RTL + +K + + T+C R + + + L + Sbjct: 248 FGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFA 307 Query: 311 ALATQV-PGFDVMLEPAATSLDVASVDPALHAADPLAARALSESFGILYRQGIPAAQRAR 369 AT V G ++ EPAA V +AA A E G+++R+ + Sbjct: 308 TDATLVQSGAVILGEPAA-----GYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPD 362 Query: 370 WQPQVAAALFTCDAQGDSVCAARLRALGSAQMDHRTATLLWFRAYAGLLLDGVWSALFQH 429 P + A L CD + A + G W +++ ++ L ++ Sbjct: 363 ESPVLMATLMECDENNQPLAGAYIDRSGLDAET-------WLTQLFRVVVVPLYHLLCRY 415 Query: 430 GIALEPHLQNTVIGFADGWPTRVWVRDLEGT-KLLAHHWPAARLRGVGERARQSLYYTPE 488 G+AL H QN + +G P RV ++D +G +L+ +P + + + R Sbjct: 416 GVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPE--MDSLPQEVRDVTSRLSA 473 Query: 489 QGWNRVAYCALVNNLAEAIFHLGEGDAALQARLWRCVGEIALRWQQRHGAQAALQGLLD- 547 + I L + R ++ + + + ++H + L Sbjct: 474 DYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSL 533 Query: 548 GAPLPGKNNLGTRLWQRADRQSDYTALPNPI 578 P + L D LPN + Sbjct: 534 FRPQIIRVVLNPVKLTWPDLDGGSRMLPNYL 564
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 36.7 bits (85), Expect = 1e-04 Identities = 48/224 (21%), Positives = 79/224 (35%), Gaps = 32/224 (14%) Query: 31 DLAALDTHAAWMRAQLPAQCELFYAAKANA----EPPILRTLAPHVDGFEAASGGELAWL 86 DL AL + + +R Q ++ KANA I + DGF + E L Sbjct: 10 DLQALKQNLSIVR-QAATHARVWSVVKANAYGHGIERIWSAI-GATDGFALLNLEEAITL 67 Query: 87 HAQQPQAPLLFGGPGKLDTELAQAAALPDCTVHVESLSELERLAEVASHAGRCVPVFLRM 146 + + P+L G + + T V S +L+ L + ++L++ Sbjct: 68 RERGWKGPILMLE-GFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARL--KAPLDIYLKV 124 Query: 147 NIAVPGAQSTRLMMGGQPSPFGLDPCDLHAAMQRLQASPSLRLAGFHFHLMSHQRDATAQ 206 N + RL G P + Q+L+A ++ LMSH +A Sbjct: 125 NSGM-----NRL---------GFQPDRVLTVWQQLRAMANVGEMT----LMSHFAEAEHP 166 Query: 207 LHLVAAYLRTVQQWRQAYALGPLRVNAGGGFGVDYLAPEASFDW 250 + A R ++Q + N+ PEA FDW Sbjct: 167 DGISGAMAR-IEQAAEGLECRRSLSNSAATL----WHPEAHFDW 205
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.017 Identities = 11/38 (28%), Positives = 18/38 (47%) Query: 239 GGALELPAARRVIAARPAGGWRDIRMFLSQPALMQAEL 276 GG EL + P G+R IR+ L + + + +L Sbjct: 338 GGDKELSYLQLPKELNPFLGFRAIRLCLEKQDIFRTQL 375
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 36.4 bits (84), Expect = 2e-05 Identities = 12/48 (25%), Positives = 26/48 (54%) Query: 1 MIRKQRTRGFTLIELLVALAVFALVAAAAVAVMRQSIDQRDAVRARLQ 48 M + RGFTL+E++V + + ++A+ V + + ++ D +A Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 26.0 bits (57), Expect = 0.038 Identities = 9/16 (56%), Positives = 13/16 (81%) Query: 12 GFSLLELMVALAIFGM 27 GF+LLE+MV + I G+ Sbjct: 9 GFTLLEIMVVIVIIGV 24
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 53.8 bits (129), Expect = 8e-12 Identities = 22/77 (28%), Positives = 40/77 (51%), Gaps = 5/77 (6%) Query: 8 MRARGFTLLEVLAVLVITALASTLVVMTLPDTRRDLHDHADTLAS---ALMHARDEAIMS 64 MR RGFTLLE++ +L++ +++ +V++ P +R D A TLA L + + + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDD--SAAQTLARFEAQLRFVQQRGLQT 58 Query: 65 LRMVEVSIDAGGYAFRR 81 + VS+ + F Sbjct: 59 GQFFGVSVHPDRWQFLV 75
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 182 bits (464), Expect = 2e-62 Identities = 65/139 (46%), Positives = 94/139 (67%), Gaps = 3/139 (2%) Query: 15 AQRRTRGFTLVELMVVIVIIGLLATVVMINVMPSQDRAMMEKARADVAVLEQALETYRLD 74 A + RGFTL+E+MVVIVIIG+LA++V+ N+M ++++A +KA +D+ LE AL+ Y+LD Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLD 62 Query: 75 NLSYPSTEQGLQALLDPPSGLTRPERYRHGGYIRRLPEDPWGHAYQYRRPGRNGGFDVYS 134 N YP+T QGL++L++ P+ Y GYI+RLP DPWG+ Y PG +G +D+ S Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLS 122 Query: 135 LGADGAEGGDADNADIGNW 153 G DG G + DI NW Sbjct: 123 AGPDGEMGTE---DDITNW 138
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 341 bits (875), Expect = e-117 Identities = 172/405 (42%), Positives = 242/405 (59%), Gaps = 8/405 (1%) Query: 1 MPQFDYTVLDLHGRNRHGVISADSINSARAQLEQRQWVPVRVEVAAATAS-------TAV 53 M Q+ Y LD G+ G ADS AR L +R VP+ V+ + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 54 RAARFSGKDLVLFTRQLATLVETA-PLEEALRTIGTQSERRGVRRVTSQTHALVVEGFRL 112 R R S DL L TRQLATLV + PLEEAL + QSE+ + ++ + + V+EG L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 113 SDAMARQGKAFPALYRAMVAAGESAGALPQVLERLADLLERQAQVRSKLQSALVYPTALA 172 +DAM +F LY AMVAAGE++G L VL RLAD E++ Q+RS++Q A++YP L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 173 ATAGAVVIVLMTFVVPKVVDQFDSMGRALPWLTRVVIGVSHFLLHAGIPLLIALVVALVA 232 A AVV +L++ VVPKVV+QF M +ALP TRV++G+S + G +L+AL+ +A Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 233 AVRLLKRPALRLAADRALLRAPLLGRLIRDLHAARMARTLAIMVNSGLPLMEGLMIAART 292 +L++ R++ R LL PL+GR+ R L+ AR ARTL+I+ S +PL++ + I+ Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 293 VDNRALRLATDSMVTAIREGGSLAAAMKRAGVFPPTLLYMASSGENSGRLAPMLERAADY 352 + N R A+REG SL A+++ +FPP + +M +SGE SG L MLERAAD Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 353 LEREFEAFTTAAMSLLEPAIIVLLGGVVAVIVLSILLPILQFNTL 397 +REF + T A+ L EP ++V + VV IVL+IL PILQ NTL Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTL 405
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 31.7 bits (71), Expect = 0.007 Identities = 18/69 (26%), Positives = 27/69 (39%), Gaps = 3/69 (4%) Query: 340 SNSNSNSNSNAAPAAAPATAPVSRTPGTPTGGASHAAIDAARPPAASSGAATAAGVAPRA 399 + S + A P AP T P TP + + + P+ + AA+ + Sbjct: 164 TKLTSEQLTTAQPDDAPGTPA---QPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQT 220 Query: 400 QPAPASAAP 408 QP P AAP Sbjct: 221 QPLPTVAAP 229
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 548 bits (1413), Expect = 0.0 Identities = 269/348 (77%), Positives = 312/348 (89%), Gaps = 1/348 (0%) Query: 1 MFKKLRGMFSNDLSIDLGTANTLIYVRGQGIVLNEPSVVAVRQDRAIGGTRSVAAVGAEA 60 M KK RGMFSNDLSIDLGTANTLIYV+GQGIVLNEPSVVA+RQDRA G +SVAAVG +A Sbjct: 1 MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDRA-GSPKSVAAVGHDA 59 Query: 61 KQMLGRTPGHITTIRPMKDGVIADFTYTEAMLKHFIKKVHKSRFLRPSPRVLVCVPAGST 120 KQMLGRTPG+I IRPMKDGVIADF TE ML+HFIK+VH + F+RPSPRVLVCVP G+T Sbjct: 60 KQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGAT 119 Query: 121 QVERRAIKESAEEAGARDVYLIEEPMAAAIGAGMPVTEARGSMVIDIGGGTTEVAVISLN 180 QVERRAI+ESA+ AGAR+V+LIEEPMAAAIGAG+PV+EA GSMV+DIGGGTTEVAVISLN Sbjct: 120 QVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN 179 Query: 181 GIVYSQSVRVGGDRFDESITNYVRRNHGMLIGEATAERIKLQIGCAYPQDEVQEMEISGR 240 G+VYS SVR+GGDRFDE+I NYVRRN+G LIGEATAERIK +IG AYP DEV+E+E+ GR Sbjct: 180 GVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGR 239 Query: 241 NLAEGVPKMIKINSNEVLEALHEPLSGIVSAVKLALEQTPPELCADVAERGIVLTGGGAL 300 NLAEGVP+ +NSNE+LEAL EPL+GIVSAV +ALEQ PPEL +D++ERG+VLTGGGAL Sbjct: 240 NLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL 299 Query: 301 LRDLDRLISEETGLHVQVADDPLTCVARGGGRALELVDMHGNEFFAPE 348 LR+LDRL+ EETG+ V VA+DPLTCVARGGG+ALE++DMHG + F+ E Sbjct: 300 LRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALEMIDMHGGDLFSEE 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 332 bits (852), Expect = e-109 Identities = 122/338 (36%), Positives = 182/338 (53%), Gaps = 28/338 (8%) Query: 349 VGSDPRMRHNLDNALKLVAHRVSILLCGATGTGKEEFAKAVHRGSPWAARPFVAVNCAAI 408 VG M+ +L+ +++++ G +GTGKE A+A+H PFVA+N AAI Sbjct: 140 VGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAI 199 Query: 409 PEALIESELFGYARGAFTDAAREGRHGKLLQASGGTLFLDEIGDMPLPLQTRLLRVLEEQ 468 P LIESELFG+ +GAFT A G+ QA GGTLFLDEIGDMP+ QTRLLRVL++ Sbjct: 200 PRDLIESELFGHEKGAFTGAQTR-STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQG 258 Query: 469 SVTPLGSDRAMPLELHVISASHRDLAQMVAAGEFREDLYYRLNGVVLHLPPLRERS-DKA 527 T +G + ++ +++A+++DL Q + G FREDLYYRLN V L LPPLR+R+ D Sbjct: 259 EYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIP 318 Query: 528 ELIRTLLR--EENGEQGVRISEEALHKLLSYAWPGNLRQLRNVLRTAAVLCSDEVIRLPN 585 +L+R ++ E+ G R +EAL + ++ WPGN+R+L N++R L +VI Sbjct: 319 DLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREI 378 Query: 586 LPQEIVDAGSAPCLVDGRAVAADDMSGRV------------------------ALDQAER 621 + E+ + A + + L + E Sbjct: 379 IENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEY 438 Query: 622 LVLQQQLERHRWNVSRTADALGISRNTLYRKLRKHGLE 659 ++ L R N + AD LG++RNTL +K+R+ G+ Sbjct: 439 PLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.8 bits (77), Expect = 4e-04 Identities = 16/78 (20%), Positives = 21/78 (26%) Query: 71 KEAPPAPAADAPPPPPAAASAPAPAPAAGSAAPAAATAAAPAALPNPAAGPAPDPATPAA 130 KEAP P P P P + A+P PA + + Sbjct: 88 KEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATS 147 Query: 131 PPATIVPIPKGPEVKVTP 148 P T V + P Sbjct: 148 KPVTSVASGPRALSRNQP 165 Score = 32.3 bits (73), Expect = 0.001 Identities = 14/64 (21%), Positives = 17/64 (26%) Query: 72 EAPPAPAADAPPPPPAAASAPAPAPAAGSAAPAAATAAAPAALPNPAAGPAPDPATPAAP 131 E P P +AP P P P P + PA P + Sbjct: 81 EPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSS 140 Query: 132 PATI 135 AT Sbjct: 141 TATA 144 Score = 31.1 bits (70), Expect = 0.003 Identities = 11/84 (13%), Positives = 15/84 (17%) Query: 71 KEAPPAPAADAPPPPPAAASAPAPAPAAGSAAPAAATAAAPAALPNPAAGPAPDPATPAA 130 + PP P + P P P AP P Sbjct: 66 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRP 125 Query: 131 PPATIVPIPKGPEVKVTPELVAEG 154 P P ++ Sbjct: 126 ASPFENTAPARPTSSTATAATSKP 149 Score = 29.6 bits (66), Expect = 0.010 Identities = 11/72 (15%), Positives = 12/72 (16%) Query: 71 KEAPPAPAADAPPPPPAAASAPAPAPAAGSAAPAAATAAAPAALPNPAAGPAPDPATPAA 130 +A P P P P P A P P P Sbjct: 63 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122 Query: 131 PPATIVPIPKGP 142 P Sbjct: 123 SRPASPFENTAP 134 Score = 28.8 bits (64), Expect = 0.018 Identities = 16/69 (23%), Positives = 16/69 (23%), Gaps = 4/69 (5%) Query: 73 APPAPAADAPPP----PPAAASAPAPAPAAGSAAPAAATAAAPAALPNPAAGPAPDPATP 128 APA PP PP P P P P A P P P P Sbjct: 53 TMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVE 112 Query: 129 AAPPATIVP 137 Sbjct: 113 QPKRDVKPV 121 Score = 28.4 bits (63), Expect = 0.027 Identities = 15/107 (14%), Positives = 23/107 (21%), Gaps = 4/107 (3%) Query: 60 LMFSVVLAACGKEAPPAPAADAPPPPPAAASAPA----PAPAAGSAAPAAATAAAPAALP 115 L+++ V AP P + P A P P P P Sbjct: 32 LLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP 91 Query: 116 NPAAGPAPDPATPAAPPATIVPIPKGPEVKVTPELVAEGKKIYFSAG 162 P P P P + + + + Sbjct: 92 VVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPT 138
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 58.3 bits (141), Expect = 6e-11 Identities = 39/136 (28%), Positives = 64/136 (47%), Gaps = 16/136 (11%) Query: 61 VDDGKSTLIGRLLYDSKRLFDDQLAALESDSRRHGTQGGRIDYALLMDGLAAEREQGITI 120 VD GK+TL LLY+S + +L +++ + R D ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAI--TELGSVDKGTTR-------------TDNTLLERQRGITI 56 Query: 121 DVAYRYFDTDRRKFIVADCPGHEQYTRNMATGASTADVAVVLVDARKGLLTQTRRHSYIV 180 F + K + D PGH + + S D A++L+ A+ G+ QTR + + Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 181 SLLGIGHVVLAVNKMD 196 +GI + +NK+D Sbjct: 117 RKMGIPTIFF-INKID 131
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 28.7 bits (64), Expect = 0.015 Identities = 39/202 (19%), Positives = 67/202 (33%), Gaps = 18/202 (8%) Query: 4 LTRTALAIALAASAAPALAQSAGH---WTTGYGAGYVSPKSNSGTVGGTQAEIKGAPALS 60 + +TA+AIA+A + +AQ+A W TG G+ A + Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAGA 60 Query: 61 FTYEYFLRNNLGVEVHAAVAGKHDLELQGIGKVGSYWSVPPSVLLQYHINGYGTVSPFVG 120 F Y + +G E+ G+ + V + L Y I + +G Sbjct: 61 FG-GYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDLDIYTRLG 119 Query: 121 VGI--NYTTFLGEDTEPTIGSGDLRFDDSIGATAHVGVDFIFNDRSGLRVDARWTDSRSN 178 + T G + GV++ R++ +WT++ + Sbjct: 120 GMVWRADTKSNVYGKNHDTGVSPV---------FAGGVEYAITPEIATRLEYQWTNNIGD 170 Query: 179 VDLNGTRLGKARIDPLTFGVSY 200 GTR L+ GVSY Sbjct: 171 AHTIGTR---PDNGMLSLGVSY 189
>PRPHPHLPASEC#Prokaryotic zinc-dependent phospholipase C signature. Length = 398 Score = 28.4 bits (63), Expect = 0.025 Identities = 6/13 (46%), Positives = 8/13 (61%) Query: 126 VHFVGDIHQPMHA 138 +H+ GDI P H Sbjct: 153 MHYFGDIDTPYHP 165
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.025 Identities = 10/22 (45%), Positives = 14/22 (63%) Query: 25 VVALVGPSGAGKTTVLNAIAGL 46 V L G G GK+T++N + GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 66.9 bits (163), Expect = 8e-15 Identities = 22/79 (27%), Positives = 43/79 (54%), Gaps = 5/79 (6%) Query: 309 PPRYPPDAVAAGLAGFVELQIAVSPTGTPEHIAIVRSTPAGVFDQTVLDAARHWRFTPAL 368 P+YP A A + G V+++ V+P G +++ I+ + PA +F++ V +A R WR+ P Sbjct: 164 QPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGK 223 Query: 369 EDGKAVASEVRVPVRFELD 387 + V + F+++ Sbjct: 224 PGSG-----IVVNILFKIN 237
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.1 bits (143), Expect = 4e-11 Identities = 22/120 (18%), Positives = 45/120 (37%), Gaps = 3/120 (2%) Query: 762 RVWCVDDEPLVCEATRTLLERWECRVDFAGGPDEALSAANAEEVPELLLLDVRMGAYHGP 821 + DD+ + L R V A + +L++ DV M + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDENAF 63 Query: 822 MLLSQLVERWQREPRVILVTAEPDPVLREHALDLG-WGFLSKPVRPPALRALVTQMLMRR 880 LL ++ + P V++++A+ + A + G + +L KP L ++ + L Sbjct: 64 DLLPRIKKARPDLP-VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.0 bits (78), Expect = 0.001 Identities = 41/174 (23%), Positives = 63/174 (36%), Gaps = 37/174 (21%) Query: 76 LMRPLGAVILGAYIDDVGRRKGLIVTL-------AIMASGTVLIVLVPGYASIGLWAPAL 128 LM+ A +LGA D GRR L+V+L AIMA+ L VL Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVL-------------- 99 Query: 129 VLLGRLLQGFSAGAEMGGVSVYLAEMATPGRRGFYASWQSASQQLAIVAAAAIGYALNQL 188 +GR++ G + GA Y+A++ R + + SA +VA +G Sbjct: 100 -YIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL---- 153 Query: 189 MAPQDLAQWGWRIPFGI-----GCVIIPFIFLLRRSLEETAEFAQRRQPVTMKQ 237 + + PF G + FLL S + +R + Sbjct: 154 -----MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLAS 202 Score = 31.7 bits (72), Expect = 0.005 Identities = 14/28 (50%), Positives = 19/28 (67%) Query: 291 LVGVSNFIWLPIGGALSDRFGRKPLLVS 318 L + F P+ GALSDRFGR+P+L+ Sbjct: 51 LYALMQFACAPVLGALSDRFGRRPVLLV 78
>TACYTOLYSIN#Bacterial thiol-activated pore-forming cytolysin signature. Length = 574 Score = 29.9 bits (67), Expect = 0.006 Identities = 17/52 (32%), Positives = 27/52 (51%), Gaps = 2/52 (3%) Query: 2 TRPSTLAAAALLVAAAFAGNAGATSKDAASTDTCA--EQPVPACNKRIVEAA 51 +R + L AAL+V NA + ++ A+T+T EQP P ++ E A Sbjct: 14 SRVAGLLTAALIVGNLVTANADSNKQNTANTETTTTNEQPKPESSELTTEKA 65
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 62.2 bits (151), Expect = 1e-13 Identities = 38/110 (34%), Positives = 56/110 (50%), Gaps = 7/110 (6%) Query: 1 MADLTILVADDHPLFRAAVIHVLQQTLPQAN--VVEASSAATLSAMLRSHPQAELVLLDL 58 M TILVADD R VL Q L +A V S+AATL + + +LV+ D+ Sbjct: 1 MTGATILVADDDAAIRT----VLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDV 55 Query: 59 AMPGARGFSALLHVRGEHPDIPVVVISSNDHPRVIRRAQQFGAAGFIPKS 108 MP F L ++ PD+PV+V+S+ + +A + GA ++PK Sbjct: 56 VMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP 105
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.0 bits (80), Expect = 2e-04 Identities = 19/86 (22%), Positives = 29/86 (33%), Gaps = 9/86 (10%) Query: 145 VEGPSGTQTLELHVFNGQGGQPPTANAAARGAAPAAPPVPSPDAAALAPPQPPQPQPVAP 204 +E P+ Q + + + +PP A PP P P+P AP Sbjct: 36 IELPAPAQPISVTMVTPADLEPPQA---------VQPPPEPVVEPEPEPEPIPEPPKEAP 86 Query: 205 VQQPGGQAPPTVPPQRSDGAQEAPRP 230 V + P P+ QE P+ Sbjct: 87 VVIEKPKPKPKPKPKPVKKVQEQPKR 112
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 5e-05 Identities = 14/45 (31%), Positives = 26/45 (57%), Gaps = 4/45 (8%) Query: 1 MKRQRGYTLIEVIVAFALLALALSL----LLGSLSGAARQVRAAD 41 +QRG+TL+E++V ++ + SL L+G+ A +Q +D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSD 48
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 30.3 bits (68), Expect = 0.003 Identities = 25/108 (23%), Positives = 48/108 (44%), Gaps = 1/108 (0%) Query: 21 RARGTSLLEMLLVIALIALAGVLAAAALNGGIDGMRLRTAGKAIASQLRYTRTQAIATGT 80 R RG +LLEM+L++ L+ ++ + A D +T + A QLR+ + + + TG Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEA-QLRFVQQRGLQTGQ 60 Query: 81 PQRFLIDPQQRRWEAPGGHHGDLPPSLEVRFTGARQVQSRQDQGAIQF 128 + P + ++ G P + ++G R + R + A Sbjct: 61 FFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSG 108
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 136 bits (343), Expect = 3e-44 Identities = 40/132 (30%), Positives = 61/132 (46%), Gaps = 18/132 (13%) Query: 15 QAGMSLLEIIIVIVLIGAVLTLVGSRVLGGADRGKANLAKSQIQTLAGKIENFQLDTGKL 74 Q G +LLEI++VIV+IG + +LV ++G ++ A S I L ++ ++LD Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 75 PSKLDDLVTQPGDSSGWLGPYVKPAELN------------DPWGHAIEYRAPGDGQPFDL 122 P+ T G S P + P N DPWG+ PG+ +DL Sbjct: 67 PT------TNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 123 ISLGKDGKPGGS 134 +S G DG+ G Sbjct: 121 LSAGPDGEMGTE 132
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 428 bits (1102), Expect = e-151 Identities = 134/411 (32%), Positives = 212/411 (51%), Gaps = 12/411 (2%) Query: 1 MPLYRYKALDAHGEMLDGQMEAASDAEVALRLQEQGHLPV---ETRLATGENDSPSLRML 57 M Y Y+ALDA G+ G EA S + L+E+G +P+ E R ++ S L L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLS-L 59 Query: 58 LRKKPFDNAALVQFTQQLATLIGAGQPLDRALSILMDLPEDEKSRRVIGDVRDTVRGGAP 117 RK + L T+QLATL+ A PL+ AL + E +++ VR V G Sbjct: 60 RRKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHS 119 Query: 118 LSSALERQHGLFSKLYINMVRAGEAGGSMQDTLQRLADYLERSRALRGKVINALIYPAIL 177 L+ A++ G F +LY MV AGE G + L RLADY E+ + +R ++ A+IYP +L Sbjct: 120 LADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVL 179 Query: 178 LAVVGCALLFLLGYVVPQFAQMYESLDVALPWFTQAVLSVGLLVRD--SWIVLIVVPGVL 235 V + LL VVP+ + + + ALP T+ ++ + VR W++L ++ G + Sbjct: 180 TVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFM 239 Query: 236 G--LWLDRKRRNAAFRASLDQWLLRQKVVGSLIARLETARLTRTLGTLLRNGVPLLAAIG 293 + L +++R +F + LL ++G + L TAR RTL L + VPLL A+ Sbjct: 240 AFRVMLRQEKRRVSF----HRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMR 295 Query: 294 IARNVMSNLALVEDVANAADDVKNGHGLSMSLARGKRFPRLALQMIQVGEESGALDTMLL 353 I+ +VMSN ++ A D V+ G L +L + FP + MI GE SG LD+ML Sbjct: 296 ISGDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLE 355 Query: 354 KTADTFELETAQAIDRALAALVPFITLVLASVVGLVIISVLVPLYDLTNAI 404 + AD + E + + AL P + + +A+VV +++++L P+ L + Sbjct: 356 RAADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 204 bits (520), Expect = 1e-62 Identities = 104/359 (28%), Positives = 148/359 (41%), Gaps = 69/359 (19%) Query: 156 PQLVPNDPLYAQYQWHLSNPNGGINAPAAWDLSQGAGVVVAVLDTGILPGHPDFAGNILQ 215 Q++ + + + I APA W+ ++G GV VAVLDTG HPD I+ Sbjct: 10 YQVIKQEQQVNEIPRGV----EMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIG 65 Query: 216 GYDFITDAEVSRRPTDARVPGALDYGDWEEADNVCYAGSQAQESSWHGTHVSGTVAEATN 275 G +F D E + + HGTHV+GT+A AT Sbjct: 66 GRNFTDDDEGDPEIFK--------------------------DYNGHGTHVAGTIA-ATE 98 Query: 276 NGVGMAGVAPKATILPVRVLGRCG-GYTSDIADAIVWASGGSVDGVPANSNPAEVINMSL 334 N G+ GVAP+A +L ++VL + G G I I +A VD +I+MSL Sbjct: 99 NENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD----------IISMSL 148 Query: 335 GGGEPCDSATQLAINSAVSRGTTVVVAAGNSSEDAAN----HSPASCNNTITVGATRITG 390 GG E A+ AV+ V+ AAGN + P N I+VGA Sbjct: 149 GGPEDVP-ELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVGAINFDR 207 Query: 391 GIAYYSNYGSKVDLSGPGGGGSVDGNPGGYIWQAGYTGATTPTSGSYTYMGLGGTSMASP 450 + +SN ++VDL PG I G Y GTSMA+P Sbjct: 208 HASEFSNSNNEVDLVAPGED----------ILSTVPGG---------KYATFSGTSMATP 248 Query: 451 HVAGVVALVQSAAIGLGDGPLTPAAVEALLKQTSRRFPVTPPASTPIGSGIVDAKAALE 509 HVAG +AL++ A + LT + A L + + +P G+G++ A E Sbjct: 249 HVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKME---GNGLLYLTAVEE 304
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 56.8 bits (136), Expect = 6e-10 Identities = 62/181 (34%), Positives = 88/181 (48%), Gaps = 28/181 (15%) Query: 764 GGDSNASGYFSTAVGGTSIANGRGATAIGYESIGNGTASTALGFASVAWGDGGTAIGTES 823 G +++A G S A+G T+ A A A+G SI G S A+G S A GD G S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 824 LAYGDDSTAVGANAAAADTGSIAVGTYANAFGPRAISLGGQSRATGDESIALGWEASAFG 883 A D A+GA A+ +DTG +++G S+A S+A+G + Sbjct: 122 TAQ-KDGVAIGARASTSDTG---------------VAVGFNSKADAKNSVAIGHSSHVAA 165 Query: 884 THSVSLGGGAVASADNSVALGAGSIADRANTVSVGAAGTERQIANVAAGTEGTDAVNLDQ 943 H S+A+G S DR N+VS+G RQ+ ++AAGT+ TDAVN+ Q Sbjct: 166 NH------------GYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQ 213 Query: 944 L 944 L Sbjct: 214 L 214 Score = 51.8 bits (123), Expect = 2e-08 Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 21/154 (13%) Query: 72 GRGAAAPASRATAIGANSHASATGAVATGADSSASGVNSSAIGRQTNAIGENAVAIGYNS 131 G A+A + AIGA + A+ AVA GA S A+GVNS AIG + A+G++AV G S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 132 FVRQSG----------ENGVALGANAGVTGANSVALGAGSRTHEDDVVSVGSGNGRGG-- 179 ++ G + GVA+G N+ NSVA+G S + S+ G+ Sbjct: 122 TAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDR 181 Query: 180 ---------PATRRITNVTAGVNATDAVNVAQLR 204 R++T++ AG TDAVNVAQL+ Sbjct: 182 ENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLK 215 Score = 51.8 bits (123), Expect = 2e-08 Identities = 69/239 (28%), Positives = 111/239 (46%), Gaps = 10/239 (4%) Query: 1095 SGESATAVGAESVANGTSAAAFGFGAEATSNYSTALGGYSSASGFNSTALGNFSTASGSN 1154 S + A+G E A G A A +S A+G + A+ + A+G S A+G N Sbjct: 40 SPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVN 99 Query: 1155 TVAVGGDAAATGAYSIAAGQGSVASGYNSVSVGGALLGLLPTEASGDYSTAVGGAAWAPG 1214 +VA+G + A G ++ G S A + V++G ++ D AVG + A Sbjct: 100 SVAIGPLSKALGDSAVTYGAASTAQK-DGVAIGA-------RASTSDTGVAVGFNSKADA 151 Query: 1215 LNSTALGNFAESTGES--SVALGADSVADRDFAVSVGSAGNERQITNVAAGTQGTDAVNL 1272 NS A+G+ + S+A+G S DR+ +VS+G RQ+T++AAGT+ TDAVN+ Sbjct: 152 KNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNV 211 Query: 1273 DQLNAVAEAGAATSKYFQASGSADSDAGAYVEGENALAAGEGANATGTGTTALGAGAQA 1331 QL E + A A+++A A + + L + + T A +A Sbjct: 212 AQLKKEIEKTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEA 270 Score = 49.9 bits (118), Expect = 8e-08 Identities = 81/308 (26%), Positives = 130/308 (42%), Gaps = 33/308 (10%) Query: 371 GTQTSASGTSSTAVGGPVDLIPGLGFFVQTQASGEASTALGAGAIASGTYTTAVGTLSEA 430 G SA G S A+G +A+ A+ A+GAG+IA+G + A+G LS+A Sbjct: 62 GLNASAKGIHSIAIGA------------TAEAAKGAAVAVGAGSIATGVNSVAIGPLSKA 109 Query: 431 SGTEATAVGYFAYAPGEG------------ATAVGPESWASGELSTALGYYS--TARGAN 476 G A G + A +G AVG S A + S A+G+ S A Sbjct: 110 LGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGY 169 Query: 477 SVALGANSVATRANTVSVGAAGDERQVTNVAAGTEGTDAVNLDQLTAVSEVASTTARSFV 536 S+A+G S R N+VS+G RQ+T++AAGT+ TDAVN+ QL E+ T + Sbjct: 170 SIAIGDRSKTDRENSVSIGHESLNRQLTHLAAGTKDTDAVNVAQLK--KEIEKTQENTNK 227 Query: 537 ATGEGAALAQGVDSVAAGSNASAYSDYSTALGSSSAASAQGATAVGSGANATTDNATAVG 596 + E A A + S ++Y+ + + + +A+ S D Sbjct: 228 RSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQS-----KDVLNMAK 282 Query: 597 FNSTAVAENTTALGGNSSASGDGSTAVGGASQATASGATALGYESIANGADSTAVGAGSV 656 +S +VA T + S +T A A AL ++ + S+ + Sbjct: 283 AHSNSVARTTLETAEEHANSVARTTLETAEEHANKKSAEALASANVYADSKSSHTLKTAN 342 Query: 657 AFGDTSTA 664 ++ D + + Sbjct: 343 SYTDVTVS 350 Score = 48.4 bits (114), Expect = 3e-07 Identities = 54/171 (31%), Positives = 82/171 (47%), Gaps = 5/171 (2%) Query: 1939 SITPAATSTAVGTTAVANHITGTAIGGSAYAHGPNDTAIGSNARVNADGSTAVGANTQIA 1998 SI AT+ A AVA A G ++ A GP A+G +A STA I Sbjct: 72 SIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIG 131 Query: 1999 AVATNA---VAMGEGAQVTAASGTAIGQGARATAQG--AVALGQGAVADRANTVSVGSVG 2053 A A+ + VA+G ++ A + AIG + A ++A+G + DR N+VS+G Sbjct: 132 ARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHES 191 Query: 2054 GERQVANVAAGTRATDAVNKGQLDSGVAAANSYTDSRYNAMADSFESYQGD 2104 RQ+ ++AAGT+ TDAVN QL + T+ R + + +Y + Sbjct: 192 LNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAYADN 242 Score = 44.1 bits (103), Expect = 5e-06 Identities = 54/142 (38%), Positives = 74/142 (52%), Gaps = 11/142 (7%) Query: 643 ANGADSTAVGAGSVAFGDTSTAVGGASVAFGADSAAFGANAAAGGTASTAIGANSSAFGE 702 A G +++A G S+A G T+ A GA+VA GA S A G N S AIG S A G+ Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVN-------SVAIGPLSKALGD 112 Query: 703 RTVALGGASNASGDDSIALGASSQASALGTTAVGSNANASIANATAVGFNS--SAGDDYA 760 V G AS A D +A+GA + S G AVG N+ A N+ A+G +S +A Y+ Sbjct: 113 SAVTYGAASTAQ-KDGVAIGARASTSDTG-VAVGFNSKADAKNSVAIGHSSHVAANHGYS 170 Query: 761 TALGGDSNASGYFSTAVGGTSI 782 A+G S S ++G S+ Sbjct: 171 IAIGDRSKTDRENSVSIGHESL 192 Score = 43.7 bits (102), Expect = 8e-06 Identities = 64/250 (25%), Positives = 105/250 (42%), Gaps = 23/250 (9%) Query: 1486 GFIPARASGTGAAAFGAGAWATADYTTAIGWNSYADGVNASALGQSAAALADNTLALGGG 1545 G + A A G + A GA A A A+G S A GVN+ A+G + AL D+ + G Sbjct: 61 GGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAA 120 Query: 1546 SRADAVGASVVGVDASATGINSTGVGRQVNAIGENAVSVGYNSFVRQSAVNGVALGANAG 1605 S A G + +G AS + + V+VG+NS + ++ Sbjct: 121 STAQKDGVA-IGARASTS---------------DTGVAVGFNSKADAKNSVAIGHSSHVA 164 Query: 1606 ATGADSVALGSGSRTYEADTVSIGSGNGRGGPATRRIVNVSDGQAATDAVNKGQLDALAA 1665 A S+A+G S+T ++VSIG + R++ +++ G TDAVN QL Sbjct: 165 ANHGYSIAIGDRSKTDRENSVSIGHES-----LNRQLTHLAAGTKDTDAVNVAQLKKEIE 219 Query: 1666 DVQTTSGMLKTTGDGVASATGDRATAA--GAGATASGARSVAVASGSRASATGASAMGVD 1723 Q + A+A D +++ G + ++S +R A S ++ Sbjct: 220 KTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQSKDVLN 279 Query: 1724 SSASGVNSTA 1733 + + NS A Sbjct: 280 MAKAHSNSVA 289 Score = 43.3 bits (101), Expect = 8e-06 Identities = 50/149 (33%), Positives = 74/149 (49%), Gaps = 11/149 (7%) Query: 552 AAGSNASAYSDYSTALGSSSAASAQGATAVGSGANATTDNATAVGFNSTAVAENTTALGG 611 A G NASA +S A+G+++ A+ A AVG+G+ AT N+ A+G S A+ ++ G Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGA 119 Query: 612 NSSASGDGSTAVGGASQATASGATALGYESIANGADSTAVGAG---------SVAFGDTS 662 S+A DG GA +T+ A+G+ S A+ +S A+G S+A GD S Sbjct: 120 ASTAQKDGVAI--GARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRS 177 Query: 663 TAVGGASVAFGADSAAFGANAAAGGTAST 691 SV+ G +S A GT T Sbjct: 178 KTDRENSVSIGHESLNRQLTHLAAGTKDT 206 Score = 41.8 bits (97), Expect = 3e-05 Identities = 48/134 (35%), Positives = 71/134 (52%), Gaps = 14/134 (10%) Query: 610 GGNSSASGDGSTAVGGASQATASGATALGYESIANGADSTAVGAGSVAFGDTSTAVGGAS 669 G N+SA G S A+G ++A A A+G SIA G +S A+G S A GD++ Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSA------- 114 Query: 670 VAFGADSAAFGANAAAGGTAST-----AIGANSSAFGERTVALGGASNASGDD--SIALG 722 V +GA S A A G AST A+G NS A + +VA+G +S+ + + SIA+G Sbjct: 115 VTYGAASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIG 174 Query: 723 ASSQASALGTTAVG 736 S+ + ++G Sbjct: 175 DRSKTDRENSVSIG 188 Score = 41.0 bits (95), Expect = 5e-05 Identities = 38/141 (26%), Positives = 71/141 (50%) Query: 1033 GAFSQASGDYAVAVGGESEAAGAQSTALGAAAGAYGDGSLAVGALSQAQGSESTAMGYFA 1092 G + A G +++A+G +EAA + A+GA + A G S+A+G LS+A G + G + Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 1093 SASGESATAVGAESVANGTSAAAFGFGAEATSNYSTALGGYSSASGFNSTALGNFSTASG 1152 +A + S ++ A F A+A ++ + + +A+ S A+G+ S Sbjct: 122 TAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDR 181 Query: 1153 SNTVAVGGDAAATGAYSIAAG 1173 N+V++G ++ +AAG Sbjct: 182 ENSVSIGHESLNRQLTHLAAG 202 Score = 39.9 bits (92), Expect = 1e-04 Identities = 37/103 (35%), Positives = 59/103 (57%), Gaps = 4/103 (3%) Query: 1691 AAGAGATASGARSVAVASGSRASATGASAMGVDSSASGVNSTAMGRQTNSIGENGVALGY 1750 A G A+A G S+A+ + + A+ A A+G S A+GVNS A+G + ++G++ V G Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGA 119 Query: 1751 NSFVRESGSNAVALGANAGASGADSVALGSGSRTYDANTVSVG 1793 S ++ G VA+GA A S VA+G S+ N+V++G Sbjct: 120 ASTAQKDG---VAIGARASTSDT-GVAVGFNSKADAKNSVAIG 158 Score = 39.9 bits (92), Expect = 1e-04 Identities = 42/128 (32%), Positives = 70/128 (54%), Gaps = 9/128 (7%) Query: 1421 AAFGGYSESTGRLSSALGYGAVASSDYSTAVGAVALASGASAVAVGEFSEATGDESVAVG 1480 A G + + G S A+G A A+ + AVGA ++A+G ++VA+G S+A GD +V G Sbjct: 59 GAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYG 118 Query: 1481 GSTFFGFIPARASGTGAAAFGAGAWATADYTTAIGWNSYADGVNASALGQSAAALADNTL 1540 ++ + A GA A +T+D A+G+NS AD N+ A+G S+ A++ Sbjct: 119 AAS--------TAQKDGVAIGARA-STSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGY 169 Query: 1541 ALGGGSRA 1548 ++ G R+ Sbjct: 170 SIAIGDRS 177 Score = 37.2 bits (85), Expect = 8e-04 Identities = 36/130 (27%), Positives = 66/130 (50%) Query: 1310 AAGEGANATGTGTTALGAGAQAVVDNATAVGVGALAGGTGAAALGNNAQAVGENSSAVGS 1369 A G A+A G + A+GA A+A A AVG G++A G + A+G ++A+G+++ G+ Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGA 119 Query: 1370 NALASEIGATANGAGAQAISTYTTALGSEAVASDNQAIAAGFRSTASNVGSAAFGGYSES 1429 + A + G + + + S+A A ++ AI A++ S A G S++ Sbjct: 120 ASTAQKDGVAIGARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKT 179 Query: 1430 TGRLSSALGY 1439 S ++G+ Sbjct: 180 DRENSVSIGH 189 Score = 34.1 bits (77), Expect = 0.006 Identities = 46/152 (30%), Positives = 75/152 (49%), Gaps = 4/152 (2%) Query: 968 AQGEDATAAGSNATADGDYGSAFGSSSQATAIGAVAIGSGASATAQYADAAGYNAAASGF 1027 + A G NA+A G + A G++++A AVA+G+G+ AT + A G + A G Sbjct: 53 VRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGD 112 Query: 1028 GSVSNGAFSQASGDYAVAVGGESEAAGAQSTALGAAAGAYGDGSLAVGALSQ--AQGSES 1085 +V+ GA S A D VA+G + + A+G + A S+A+G S A S Sbjct: 113 SAVTYGAASTAQKD-GVAIGARASTSDT-GVAVGFNSKADAKNSVAIGHSSHVAANHGYS 170 Query: 1086 TAMGYFASASGESATAVGAESVANGTSAAAFG 1117 A+G + E++ ++G ES+ + A G Sbjct: 171 IAIGDRSKTDRENSVSIGHESLNRQLTHLAAG 202 Score = 32.6 bits (73), Expect = 0.019 Identities = 42/137 (30%), Positives = 56/137 (40%), Gaps = 1/137 (0%) Query: 393 GLGFFVQTQASGEASTALGAGAIASGTYTTAVGTLSEASGTEATAVGYFAYAPGEGATAV 452 G+ Q S A ALG A G + A G + A+G A A A AV Sbjct: 30 GIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAV 89 Query: 453 GPESWASGELSTALGYYSTARGANSVALGANSVATRANTVSVGAAGDERQVTNVAAGTEG 512 G S A+G S A+G S A G ++V GA S A + + V++GA Sbjct: 90 GAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQK-DGVAIGARASTSDTGVAVGFNSK 148 Query: 513 TDAVNLDQLTAVSEVAS 529 DA N + S VA+ Sbjct: 149 ADAKNSVAIGHSSHVAA 165 Score = 31.8 bits (71), Expect = 0.030 Identities = 44/133 (33%), Positives = 64/133 (48%), Gaps = 4/133 (3%) Query: 960 GTGTGTADAQGEDATAAGSNATADGDYGSAFGSSSQATAIGAVAIGSGASATAQYADAAG 1019 G G A A+G + A G+ A A A G+ S AT + +VAIG + A A G Sbjct: 59 GAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYG 118 Query: 1020 YNAAASGFGSVSNGAFSQASGDYAVAVGGESEAAGAQSTALGAAA--GAYGDGSLAVGAL 1077 + A G V+ GA + S D VAVG S+A S A+G ++ A S+A+G Sbjct: 119 AASTAQKDG-VAIGARASTS-DTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDR 176 Query: 1078 SQAQGSESTAMGY 1090 S+ S ++G+ Sbjct: 177 SKTDRENSVSIGH 189 Score = 31.4 bits (70), Expect = 0.041 Identities = 37/113 (32%), Positives = 55/113 (48%), Gaps = 8/113 (7%) Query: 237 AAGDAANAVGTATTALGTGANAVAANATAVGANALASGQNSAAFGHNAQANGPASVAVGG 296 A G A+A G + A+G A A A AVGA ++A+G NS A GP S A+G Sbjct: 60 AGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAI-------GPLSKALGD 112 Query: 297 AAVDEDGEPLVTNGGVPVTTGATSAGVGGTAVGASANADGFAASSFGVGAYAA 349 +AV GV + A+++ G AVG ++ AD + + G ++ A Sbjct: 113 SAVTYGAASTAQKDGVAIGARASTSDT-GVAVGFNSKADAKNSVAIGHSSHVA 164
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 200 bits (510), Expect = 3e-61 Identities = 103/379 (27%), Positives = 147/379 (38%), Gaps = 80/379 (21%) Query: 137 QVDLRMYPLQTSGALPNDPLLQTNQWHLIDPVGGIDVAQAWKTTQGEGVVVAVLDTGILP 196 +V + Y + + + + + I W T+G GV VAVLDTG Sbjct: 4 KVHIIPYQV-----IKQEQQVNEIPRGV----EMIQAPAVWNQTRGRGVKVAVLDTGCDA 54 Query: 197 DHPDLAGNLLTGYDFITDPFFSRRATAERVPGALDLGDWIAEDGDCGLFSVASDSSWHGT 256 DHPDL ++ G +F D D G + D + HGT Sbjct: 55 DHPDLKARIIGGRNFT--------------------------DDDEGDPEIFKDYNGHGT 88 Query: 257 HVAGTVAEATNNGIGGAGVAYRAKVLPVRVLGHCG-GQLSDISDAIVWASGGHVDGVPDN 315 HVAGT+A AT N G GVA A +L ++VL G GQ I I +A VD Sbjct: 89 HVAGTIA-ATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD----- 142 Query: 316 RDPAEVINLSLGGGGACGSAMQAAINGAVARGTTVVVAAGNSTADVSTTA----PANCAN 371 +I++SLGG + A+ AVA V+ AAGN T P Sbjct: 143 -----IISMSLGGPED-VPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYNE 196 Query: 372 VIAVAATRATGALADYSNFGRQIDLAGPGGSSMFFATNDGPIRSFVWQTLYTGKTTPTSG 431 VI+V A +++SN ++DL PG + T+ GK Sbjct: 197 VISVGAINFDRHASEFSNSNNEVDLVAPG--------------EDILSTVPGGKYA---- 238 Query: 432 QFTYGGSDFAGTSMASPHVAGTAALVQSALIADGKPPLSPAAMENLLKRTARAFPVSIPV 491 F+GTSMA+PHVAG AL++ A + L+ + L + S Sbjct: 239 -------TFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNS--- 288 Query: 492 ATPAGSGIVDAGAAVARAL 510 G+G++ A + Sbjct: 289 PKMEGNGLLYLTAVEELSR 307
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 54.9 bits (131), Expect = 9e-10 Identities = 63/242 (26%), Positives = 104/242 (42%), Gaps = 19/242 (7%) Query: 323 SDYAIAIGYDSNVFPNAPGNTDA-------VAIGHSAGSFAPRTVSLGGFALASGDGGIS 375 +D A+ + Y G +A +AIG +A + V++G ++A+G ++ Sbjct: 43 ADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVA 102 Query: 376 IGHDSTAYNENSVALGARATTSRFNGDSTVVGADAQANGVDAVAIGYGAKVGSWVDDAWN 435 IG S A +++V GA +T + D +GA A + VA+G+ +K + A Sbjct: 103 IGPLSKALGDSAVTYGAASTAQK---DGVAIGARASTSDT-GVAVGFNSKADAKNSVAIG 158 Query: 436 RSASSA------VALGAHSYAFRSNTVSVGDVQAGLTRQITSVAAGTEATDAVNVAQLDT 489 S+ A +A+G S R N+VS+G L RQ+T +AAGT+ TDAVNVAQL Sbjct: 159 HSSHVAANHGYSIAIGDRSKTDRENSVSIG--HESLNRQLTHLAAGTKDTDAVNVAQLKK 216 Query: 490 VRAATSRIDGYLAVTPATTDATAASAQGQGAMALGGASSALGASATAVGFNASSVGQSSS 549 T + A + + + + ++ T + QS Sbjct: 217 EIEKTQENTNKRSAELLANANAYADNKSSSVLGIANNYTDSKSAETLENARKEAFAQSKD 276 Query: 550 AL 551 L Sbjct: 277 VL 278 Score = 53.0 bits (126), Expect = 4e-09 Identities = 55/168 (32%), Positives = 82/168 (48%), Gaps = 5/168 (2%) Query: 814 SITPAATSTAVGTAAVANHITGTAIGGSAYAHGPNDTAIGSNARVNADGSTAVGANTQIA 873 SI AT+ A AAVA A G ++ A GP A+G +A STA I Sbjct: 72 SIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIG 131 Query: 874 AVATNA---VAMGEGAQVTAASGTAIGQGARATAQG--AVALGQGAVADRANTVSVGSVG 928 A A+ + VA+G ++ A + AIG + A ++A+G + DR N+VS+G Sbjct: 132 ARASTSDTGVAVGFNSKADAKNSVAIGHSSHVAANHGYSIAIGDRSKTDRENSVSIGHES 191 Query: 929 GERQVANVAAGTRATDAVNKGQLDSGVAAANSYTDSRYNAMADSFESY 976 RQ+ ++AAGT+ TDAVN QL + T+ R + + +Y Sbjct: 192 LNRQLTHLAAGTKDTDAVNVAQLKKEIEKTQENTNKRSAELLANANAY 239 Score = 47.2 bits (111), Expect = 3e-07 Identities = 55/177 (31%), Positives = 89/177 (50%), Gaps = 24/177 (13%) Query: 510 ATAASAQGQGAMALGGASSALGASATAVGFNASSVGQSSSALGSLAVAAGERSVAVASGS 569 ASA+G ++A+G + A +A AVG + + G +S A+G L+ A G+ +V + S Sbjct: 62 GLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAAS 121 Query: 570 RAAATGASALGADSSASGVNSTAMGRQTNSIAENGVALGYNSFVRESGSNAVALGANAGA 629 A G A+GA +S S + GVA+G+NS S A+ ++ A Sbjct: 122 TAQKDGV-AIGARASTS---------------DTGVAVGFNSKADAKNSVAIGHSSHVAA 165 Query: 630 SGADSVALGSGSRTYDANTVSVGSGNGRGGPATRRIVNVGAGTIASASTDAINGGQL 686 + S+A+G S+T N+VS+G + R++ ++ AGT TDA+N QL Sbjct: 166 NHGYSIAIGDRSKTDRENSVSIGHES-----LNRQLTHLAAGT---KDTDAVNVAQL 214 Score = 41.8 bits (97), Expect = 1e-05 Identities = 33/97 (34%), Positives = 54/97 (55%), Gaps = 2/97 (2%) Query: 189 ASGVGATAVGGGALAGTPYASAIGSGASASGVQSTALGYRAQTSSDGATAVGGLSSASGF 248 A G+ + A+G A A A A+G+G+ A+GV S A+G ++ D A G S+A Sbjct: 67 AKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKD 126 Query: 249 LSTAGGYSSRASADTSTAFGYRARSDGASSVAVGDTS 285 G +S ++DT A G+ +++D +SVA+G +S Sbjct: 127 GVAIGARAS--TSDTGVAVGFNSKADAKNSVAIGHSS 161 Score = 36.8 bits (84), Expect = 4e-04 Identities = 52/171 (30%), Positives = 78/171 (45%), Gaps = 16/171 (9%) Query: 175 ANGFVVGQREQATQASGVGATAVGGGALAGTPYASAIGSGASASGVQSTALGYRAQTSSD 234 A+ + A Q S A+G P A G ASA G+ S A+G A+ + Sbjct: 25 ADDYDGIPNLTAVQISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKG 84 Query: 235 GATAVGGLSSASGFLSTAGGYSSRASADTSTAFG--YRARSDGA----------SSVAVG 282 A AVG S A+G S A G S+A D++ +G A+ DG + VAVG Sbjct: 85 AAVAVGAGSIATGVNSVAIGPLSKALGDSAVTYGAASTAQKDGVAIGARASTSDTGVAVG 144 Query: 283 DTSLASGAQSVVVGGVSNFGSITAATGLGGIALGSGAQSQSDYAIAIGYDS 333 S A SV +G S+ AA IA+G +++ + +++IG++S Sbjct: 145 FNSKADAKNSVAIGHSSH----VAANHGYSIAIGDRSKTDRENSVSIGHES 191 Score = 31.0 bits (69), Expect = 0.029 Identities = 37/139 (26%), Positives = 66/139 (47%), Gaps = 9/139 (6%) Query: 104 PAADAEIPAFADGEDALALGNASNALGDGTMALGGGSLALDRDATAIGHNAAAAGESSIA 163 + A A G ++A+G + A +A+G GS+A ++ AIG + A G+S++ Sbjct: 57 VPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKALGDSAVT 116 Query: 164 LGGVATVFDYDANGFVVGQREQATQASGVGATAVGGGALAGTPYASAIG--SGASASGVQ 221 G +T +G +G R + AVG + A + AIG S +A+ Sbjct: 117 YGAASTA---QKDGVAIGARASTSDT----GVAVGFNSKADAKNSVAIGHSSHVAANHGY 169 Query: 222 STALGYRAQTSSDGATAVG 240 S A+G R++T + + ++G Sbjct: 170 SIAIGDRSKTDRENSVSIG 188
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 27.5 bits (61), Expect = 0.040 Identities = 12/65 (18%), Positives = 19/65 (29%), Gaps = 4/65 (6%) Query: 118 ASNVAVSAKLTYQDGQVAGEQN---ATLNTTGAETTNLS-FSKPDGWPAGTYTAQVMVDG 173 + V+ Q + E L +LS F P GTY + ++ Sbjct: 27 FVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNN 86 Query: 174 KPAGT 178 T Sbjct: 87 GYMAT 91
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.3 bits (128), Expect = 8e-10 Identities = 30/149 (20%), Positives = 57/149 (38%), Gaps = 22/149 (14%) Query: 64 ASALGTVTAL-NTVTVSPQVGGQLMSLNFKEGQEVKKGDLLAQIDPRT-------LQASY 115 A+A G +T + + P + + KEG+ V+KGD+L ++ Q+S Sbjct: 84 ATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSL 143 Query: 116 DQALAAKRQNQALLA---TSRVNYQRSNDPAYKQYVS-----------RTDLDTQRNQVA 161 QA + + Q L +++ + D Y Q VS + T +NQ Sbjct: 144 LQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKY 203 Query: 162 QYEAAVAANDAQMRSAQVQLQFTRVTAPI 190 Q E + A+ + ++ + + Sbjct: 204 QKELNLDKKRAERLTVLARINRYENLSRV 232 Score = 35.2 bits (81), Expect = 5e-04 Identities = 22/177 (12%), Positives = 64/177 (36%), Gaps = 29/177 (16%) Query: 93 EGQEVKKGDLLAQIDPRTLQASYDQ-------ALAAKR----------QNQALLATSRVN 135 + + ++ +LA+I+ + ++ +L K+ +N+ + A + + Sbjct: 210 DKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELR 269 Query: 136 YQRSNDPAYKQYVSRTDLD-TQRNQVAQYEAAVAANDAQMRSAQV---------QLQFTR 185 +S + + + Q+ + E + + Q + Sbjct: 270 VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASV 329 Query: 186 VTAPIDGIAGIRGV-DVGNIVTSSSTIVTLT-QIRPIYVSFNLPERELQAVRTGQTA 240 + AP+ V G +VT++ T++ + + + V+ + +++ + GQ A Sbjct: 330 IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNA 386
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 732 bits (1892), Expect = 0.0 Identities = 296/1072 (27%), Positives = 497/1072 (46%), Gaps = 65/1072 (6%) Query: 23 STIFIRRPIATSLLMAGVLLLGILGYRQLPVSALPEIDAPSLVVTTQYPGANATTMASLV 82 + FIRRPI +L +++ G L QLPV+ P I P++ V+ YPGA+A T+ V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 83 TTPLERQFGQISGLQMMTSDS-SAGLSTIILQFSMERDIDIASQDVQAAIRQAT--LPSS 139 T +E+ I L M+S S SAG TI L F D DIA VQ ++ AT LP Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 140 LPYQPVYNRVNPADAAILTLKLTSDS--LPLREVNRYADAILAQRLSQVPGVGLVSIAGN 197 + Q + + + ++ SD+ +++ Y + + LS++ GVG V + G Sbjct: 122 VQQQGIS-VEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 198 VRPAVRIQVNPAQLSNMGLTMESLRSALTQTNVSAPKGSLN------GKTQSYSIGTNDQ 251 A+RI ++ L+ LT + + L N G L G+ + SI + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 252 LTDAAQYRETII-SYKDGRPVRLADVANVVDGVENDQLAAWADGKQAVLLEIRRQPGANI 310 + ++ + + DG VRL DVA V G EN + A +GK A L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 311 VQTVEQIRNILPQLRSVLPADVHLEVFSDRTETIRASVHEVKFTLVLTIALVVAVIFVFL 370 + T + I+ L +L+ P + + D T ++ S+HEV TL I LV V+++FL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 371 RRLWATIIPSVAVPLSLAGTFGVMAFAGMSLDNLSLMALVVATGFVVDDAIVMIENIVRY 430 + + AT+IP++AVP+ L GTF ++A G S++ L++ +V+A G +VDDAIV++EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 431 IEQGKSGP-EAAEIGAKQIGFTVLSLTVSLVAVFLPLLLMPGVTGRLFHEFAWVLSIAVV 489 + + K P EA E QI ++ + + L AVF+P+ G TG ++ +F+ + A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 490 ISMLVSLTLTPMMCAYLLKPDALPEGEDAHERASAAGKTNLWTRTVGAYERSLDWVLAHQ 549 +S+LV+L LTP +CA LLKP + E ++ + +V Y S+ +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHE--NKGGFFGWFNTTFDHSVNHYTNSVGKILGST 537 Query: 550 PLTLAVAIGAVALTVVLYVAIPKGLLPEQDTGLITGVVQADQNVAFPQMEQRTQAVAAAL 609 L + VA VVL++ +P LPE+D G+ ++Q + ++ V Sbjct: 538 GRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYY 597 Query: 610 RKDPA--VTGVAAFIGAGTMNPTLNQGQLSIVLKTRGDREG----LDEVLPRLQNAVAGI 663 K+ V V G N G + LK +R G + V+ R + + I Sbjct: 598 LKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKI 657 Query: 664 PGVALFLKPVQDV-TLDTRVAATEYQYSISDVDSSELATWAGR-MTEAMRKLPELADVDN 721 + + + L T + + L + + A + L V Sbjct: 658 RDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 722 NLANQGRALELSIDRDKASMLGVPMQTIDDTLYDSFGQRQISTIFTELNQYRVVLEVAPE 781 N +L +D++KA LGV + I+ T+ + G ++ ++ ++ + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 782 FRTSTALMNQLAVASNGSGALTGTNATSFGQVTSSNSSTATGVGAQNTGIVVGAGSIIPL 841 FR +++L V S G ++P Sbjct: 778 FRMLPEDVDKLYVRSA-------------------------------------NGEMVPF 800 Query: 842 AALAEAKVTNTPLVVSHQQQLPAVTISFNLAPGHSLSQAVAAIEKAREELKIPTQVHAQF 901 +A + + LP++ I APG S A+A +E +L P + + Sbjct: 801 SAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKL--PAGIGYDW 858 Query: 902 VGKAAEFTGSQTDIVWLLLASIVVIYIVLGVLYESYIHPLTIISTLPPAGVGALLALMMC 961 G + + S L+ S VV+++ L LYES+ P++++ +P VG LLA + Sbjct: 859 TGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLF 918 Query: 962 GLSLSVDGIVGIVLLIGIVKKNAIMMIDFAIDA-RREGATAHDAIRRACLLRFRPIMMTT 1020 V +VG++ IG+ KNAI++++FA D +EG +A A +R RPI+MT+ Sbjct: 919 NQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTS 978 Query: 1021 AAAMLGALPLALGTGIGSELRRPLGIAIVGGLLLSQLVTLYTTPVIYLYMER 1072 A +LG LPLA+ G GS + +GI ++GG++ + L+ ++ PV ++ + R Sbjct: 979 LAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 76.4 bits (188), Expect = 4e-16 Identities = 58/319 (18%), Positives = 117/319 (36%), Gaps = 14/319 (4%) Query: 766 FTELNQYRVVLEVAPEFRTSTALMNQLAVASNGS-GALTGTNATSFGQVTSSNSSTATGV 824 LN+Y++ L Q + G G + + Sbjct: 190 ADLLNKYKLTPV-----DVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPE 244 Query: 825 GAQNTGIVVGA-GSIIPLAALAEAKVT--NTPLVVSHQQQLPAVTISFNLAPGHSLSQAV 881 + V + GS++ L +A ++ N ++ + PA + LA G + Sbjct: 245 EFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGANALDTA 303 Query: 882 AAIEKAREELK--IPTQVHAQFVGKAAEF-TGSQTDIVWLLLASIVVIYIVLGVLYESYI 938 AI+ EL+ P + + F S ++V L +I+++++V+ + ++ Sbjct: 304 KAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMR 363 Query: 939 HPLTIISTLPPAGVGALLALMMCGLSLSVDGIVGIVLLIGIVKKNAIMMIDFAIDARRE- 997 L +P +G L G S++ + G+VL IG++ +AI++++ E Sbjct: 364 ATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMED 423 Query: 998 GATAHDAIRRACLLRFRPIMMTTAAAMLGALPLALGTGIGSELRRPLGIAIVGGLLLSQL 1057 +A ++ ++ +P+A G + R I IV + LS L Sbjct: 424 KLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL 483 Query: 1058 VTLYTTPVIYLYMERAGER 1076 V L TP + + + Sbjct: 484 VALILTPALCATLLKPVSA 502
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 750 bits (1937), Expect = 0.0 Identities = 287/1034 (27%), Positives = 492/1034 (47%), Gaps = 26/1034 (2%) Query: 3 ISAPFIKRPIGTSLLAIGLFVIGLMCYLRLGVAALPNIQIPIIFVHATQSGADASTMAST 62 ++ FI+RPI +LAI L + G + L+L VA P I P + V A GADA T+ T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 63 VTAPLERHLGQLPGIDRMRSSS-SESSSLVVLVFQSSRNIDSAAQDIQTAINASQSDLPS 121 VT +E+++ + + M S+S S S + L FQS + D A +Q + + LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 122 GLGTPMYSKANPNDDPVIAIALTSET--QSADELYNVADSLLAQRLRQITGISSVDIAGA 179 + S + ++ S+ + D++ + S + L ++ G+ V + GA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 180 STPAVRVDVDLRALNALGLTPDDLRNAVRAANVTSPTGFL------SDGNTTMAIISNDS 233 A+R+ +D LN LTP D+ N ++ N G L +II+ Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 234 VSKAADFAQLAISTQSNGRIVRLGDVATVDDGQQDAYQAAWFDGKPAVVMYAFTRAGANI 293 +F ++ + S+G +VRL DVA V+ G ++ A +GKPA + GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 VETVDQVKAQIPELRSYLQPGTTLTPYFDRTPTIRASLHEVQATLMISLAMVILTMALFL 353 ++T +KA++ EL+ + G + +D TP ++ S+HEV TL ++ +V L M LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 RRLAPTLIAAVTVPLSLAGSALVMYVLGFTLNNLSLLALVIAIGFVVDDAIVVIENVMRH 413 + + TLI + VP+ L G+ ++ G+++N L++ +V+AIG +VDDAIVV+ENV R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 L-DEGMSRLDAALAGAREIGFTIVSITASLVAVFIPMLFASGMIGAFFREFTVTLVAAIV 472 + ++ + +A +I +V I L AVFIPM F G GA +R+F++T+V+A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 VSMLVSLTLTPALCSRFLSPHAEP--ETPDRFGAWLDRMHERMLRAYTVALDFSLRHALL 530 +S+LV+L LTPALC+ L P + E F W + + + YT ++ L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 531 LSLTPLLLIAATIFLGSAVKKGSFPAQDTGLIWGRANSSATVSFADMVSRQRRITDMLMA 590 L L++A + L + P +D G+ A + ++TD + Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 591 DP-----AVKTVGARLGSGRQGSSASFNIELKKRDE--GRRDTTAEVVARLSAKADRYPD 643 + +V TV SG+ ++ + LK +E G ++ V+ R + + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 644 LDLRLRAIQDLPSDGGGGTSQGAQYRVSLQGNDLAQLQEWLPKLQAALKKNP-HLRDVGT 702 D + G + + G L + +L ++P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 703 DVDTAGLRQNIVIDRAKAARLGISVGAIDGALYGAFGQRSISTIYSDLNQYSVVVNALPS 762 + + + +D+ KA LG+S+ I+ + A G ++ + V A Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 763 QTATPKALDQIFVPNRAGQMVPITAVATQAPGLAPPQIIHENQYTTMELSYNLAPGVSTG 822 P+ +D+++V + G+MVP +A T P++ N +ME+ APG S+G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 823 EADLIIKSTVEGLRMPDGIRLS-GDDSFNVQLSPNSMGILLLAAVLTVYIVLGMLYESLI 881 +A ++++ ++P GI S+ +LS N L+ + + V++ L LYES Sbjct: 838 DAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 882 HPVTILSTLPAAGVGALLALFITNTELSVISMIALVLLIGIVKKNAIMMIDFALVAQRVH 941 PV+++ +P VG LLA + N + V M+ L+ IG+ KNAI++++FA Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 942 GMDARAAAREASIVRFRPIMMTTMVAILAAVPLAVGLGEGSELRRPLGIAMIGGLVFSQS 1001 G A A +R RPI+MT++ IL +PLA+ G GS + +GI ++GG+V + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1002 LTLLSTPALYVIFS 1015 L + P +V+ Sbjct: 1016 LAIFFVPVFFVVIR 1029 Score = 108 bits (271), Expect = 6e-26 Identities = 80/506 (15%), Positives = 164/506 (32%), Gaps = 31/506 (6%) Query: 2 NISAPFIKRPIGTSLLAIGLFVIGLMCYLRLGVAALPNIQIPIIFVHA-TQSGADASTMA 60 N + L+ + ++ +LRL + LP + +GA Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 STVT----------APLERHLGQLPGIDRMRSSSSESSSLVVLVFQSSRNIDS-AAQDIQ 109 + + + G + + + V L RN D +A+ + Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 110 TAINASQSDLPSGLGTPMYSKANPNDDPVIAIALTSETQSA-----DELYNVADSLLAQR 164 + G P + A E D L + LL Sbjct: 648 HRAKMELGKIRDGFVIPF--NMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMA 705 Query: 165 LRQITGISSVDIAG-ASTPAVRVDVDLRALNALGLTPDDLRNAVRAANVTSPTGFLSDGN 223 + + SV G T +++VD ALG++ D+ + A + D Sbjct: 706 AQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRG 765 Query: 224 TTMAIIS---NDSVSKAADFAQLAISTQSNGRIVRLGDVATVDDGQQDAYQAAWFDGKPA 280 + D +L + + +NG +V T + + ++G P+ Sbjct: 766 RVKKLYVQADAKFRMLPEDVDKLYVRS-ANGEMVPFSAFTTSHWVYG-SPRLERYNGLPS 823 Query: 281 VVMYAFTRAGANIVETVDQVKAQIPELRSYLQPGTTLTPYFDRTPTIRASLHEVQATLMI 340 + + G + A + L S L G + + R S ++ A + I Sbjct: 824 MEIQGEAAPGTS----SGDAMALMENLASKLPAGIGYD-WTGMSYQERLSGNQAPALVAI 878 Query: 341 SLAMVILTMALFLRRLAPTLIAAVTVPLSLAGSALVMYVLGFTLNNLSLLALVIAIGFVV 400 S +V L +A + + + VPL + G L + + ++ L+ IG Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 401 DDAIVVIENVM-RHLDEGMSRLDAALAGAREIGFTIVSITASLVAVFIPMLFASGMIGAF 459 +AI+++E EG ++A L R I+ + + + +P+ ++G Sbjct: 939 KNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGA 998 Query: 460 FREFTVTLVAAIVVSMLVSLTLTPAL 485 + ++ +V + L+++ P Sbjct: 999 QNAVGIGVMGGMVSATLLAIFFVPVF 1024
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 250 bits (641), Expect = 8e-82 Identities = 156/398 (39%), Positives = 224/398 (56%), Gaps = 7/398 (1%) Query: 17 ALIFIFITVLIDVLSFGVIIPVLPDLVRHFTGGDYVVAAGWIGWFGFLFAAIQFVCSPLQ 76 LI I TV +D + G+I+PVLP L+R + V A G L+A +QF C+P+ Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAH--YGILLALYALMQFACAPVL 63 Query: 77 GALSDRFGRRPVILLSCLGLGLDFILMAIAHSLPMLLLARVISGVCSASFSTANAYIADV 136 GALSDRFGRRPV+L+S G +D+ +MA A L +L + R+++G+ A+ + A AYIAD+ Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADI 123 Query: 137 TPPDKRAGAFGMLGAAFGIGFVAGPLIGGWLGSIGLRWPFWFAAGLALLNVLYGWFVLPE 196 T D+RA FG + A FG G VAGP++GG +G PF+ AA L LN L G F+LPE Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 197 SLPAQRRTARLDWSHANPLGALKLLRRYPQVFGLASVVFLANLAHYVYPSIFVLFAGYQY 256 S +RR R + NPL + + R V L +V F+ L V +++V+F ++ Sbjct: 184 SHKGERRPLRREAL--NPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241 Query: 257 HWGPREVSWVLAGVGICSIIVNALLVGRLVRRLGERRALLLGLGCGVIGFIIYGLADSGT 316 HW + LA GI + A++ G + RLGERRAL+LG+ G+I+ A G Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 317 AFLIGVPISALWAIAAPSAQALITREVGADAQGRVQGALTGLVSLAGIVGPLLFANVFAW 376 + + A I P+ QA+++R+V + QG++QG+L L SL IVGPLLF ++A Sbjct: 302 MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361 Query: 377 FIGS--GAPLHLPGAPWLLAAVLLAAG-WGMAWKRAAR 411 I + G A +LL L G W A +RA R Sbjct: 362 SITTWNGWAWIAGAALYLLCLPALRRGLWSGAGQRADR 399
>SECA#SecA protein signature. Length = 901 Score = 31.0 bits (70), Expect = 0.001 Identities = 9/16 (56%), Positives = 10/16 (62%) Query: 7 DPCPCGRPADYARCCG 22 DPCPCG Y +C G Sbjct: 883 DPCPCGSGKKYKQCHG 898
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 47.0 bits (111), Expect = 6e-07 Identities = 46/247 (18%), Positives = 82/247 (33%), Gaps = 27/247 (10%) Query: 1108 IEYDEQAQRLKLPERSRGDEPAVADATDAAPS--IEAAAESAGVQGAA-------SADGM 1158 I+ D + E +R DE V A PS E AE++ + + + Sbjct: 1003 IQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETT 1062 Query: 1159 ATNGVPMHTASPATEETPPAAQ---------ETQTGQRKPAVATTSKQNKTAKTASSTRA 1209 A N A + + ETQT + K AT K+ K T+ Sbjct: 1063 AQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKET-ATVEKEEKAKVETEKTQE 1121 Query: 1210 AAQPQAK-RPKKSPSRTPALAGKPASDKRPA-GVPAVSSGVASRSNVGKTTRSSKTPGKP 1267 + ++ PK+ S T +PA + P + S + ++ + + + + + Sbjct: 1122 VPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQ 1181 Query: 1268 IAATSASNATSRKVAAASAALKTAAAKPRATAASTGQPARGAGKTTSTRAVAKPSPATTR 1327 S + T V A +P + S+ +P K R+V + P Sbjct: 1182 PVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKP-----KNRHRRSV-RSVPHNVE 1235 Query: 1328 GAKAGAP 1334 A + Sbjct: 1236 PATTSSN 1242
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.4 bits (66), Expect = 0.038 Identities = 37/224 (16%), Positives = 74/224 (33%), Gaps = 44/224 (19%) Query: 48 AVLHARLQRQLDALRADELSRELPRTAQAYLAHWLAQGWLERRLPEGAAEEEYELSRAAT 107 A +H ++ ++S E+ + A ++ + ++ E+ A Sbjct: 19 AFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAAHL 78 Query: 108 QAI-------RFIVGLRESSSSATESRLSLVIQQLVQLAGQTEADPEL--RLAALRDERA 158 + + +A E L V V + + + + R A +RD Sbjct: 79 LVLDDPELVDGIKGKIENEQMNA-EYALKEVSDMFVSMFESMD-NEYMKERAADIRDVSK 136 Query: 159 RIDAEIERVASGRVAALDGKRALERARDLIHLSDELAEDFHRVRDDFEQLNRQFRERIID 218 R+ + V +G +A + + + ++++L D QLN+QF + Sbjct: 137 RVLGHLIGVETGSLATIA--------EETVIIAEDLTPS------DTAQLNKQFVKGFAT 182 Query: 219 DEGAR-------------------GDVLEQLFDGVDVIADSEAG 243 D G R +V E++ G VI D G Sbjct: 183 DIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEG 226
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.002 Identities = 11/43 (25%), Positives = 21/43 (48%), Gaps = 3/43 (6%) Query: 71 GLIGIGLVVGIVASFL---PASIGNALSIPLALLGGMSANYAY 110 I LV ++ FL A++ +++P+ LLG + A+ Sbjct: 344 LFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAF 386
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 29.6 bits (66), Expect = 0.030 Identities = 38/140 (27%), Positives = 48/140 (34%), Gaps = 22/140 (15%) Query: 245 VITEAVDACVRDGTSWDLELPLTSATGRRL---------WVHSTGSVEHVDGRKRLIGAV 295 ++ + C R G LE P RL W+ +EHV L GA Sbjct: 14 LLAQTATECQRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWLEHVS--PALAGAA 71 Query: 296 QDVTDRHRAVDALAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAARSL--GRSVEQM 353 H V LAA+ER F L H RL NP +L G+ + M Sbjct: 72 VSAGAEHLVVPWLAATERPFE--------LPVPHLSCRRLCVENPVPGSALPEGKLLHIM 123 Query: 354 EGRSLVEFVR-PERHAALRG 372 R + F PE A G Sbjct: 124 SDRGGLWFEHLPELPAVGGG 143
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.035 Identities = 11/49 (22%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 308 PLQALLAQDRRSQLLKTLSVWFGAGMRMAPTAKALGIHRNTLDYRMQRI 356 +LA+ +L L+ A LG++RNTL +++ + Sbjct: 428 LYDRVLAEMEYPLILAALTA---TRGNQIKAADLLGLNRNTLRKKIREL 473