>PF06872#EspG protein Length = 398 Score = 28.5 bits (63), Expect = 0.021 Identities = 14/54 (25%), Positives = 27/54 (50%) Query: 111 LLLEAGMEVNDDFKEPTDHLAIYLELLSHLHFSLGESFQQRRMNKLRQKTLSSL 164 L+L+A +++N D+K+P + + +LL L L + + Q L+ L Sbjct: 29 LVLDATIKINSDYKKPWNEMTCAEKLLKILTLGLWNPKYSQDERQQFQGLLTVL 82
>PF06580#Sensor histidine kinase Length = 349 Score = 24.8 bits (54), Expect = 0.031 Identities = 11/66 (16%), Positives = 20/66 (30%), Gaps = 3/66 (4%) Query: 1 MSPAFSSWSDFFAMGGYAFFVWLAVAMTVAPLVLLALHTVLQRRAILRGVAQQRAREARM 60 P + F V + M ++ I + A+EA++ Sbjct: 107 TKPVAFTLPLA---LSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQL 163 Query: 61 RAAQAQ 66 A +AQ Sbjct: 164 MALKAQ 169
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 58.0 bits (140), Expect = 2e-11 Identities = 48/189 (25%), Positives = 85/189 (44%), Gaps = 11/189 (5%) Query: 5 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMAQALNVREGAVQSVMAAYLLTYGVSQLFYG 64 R+ +L+ L +L + + + ++ D+A N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 65 PLSDRVGRRPVILVGMSIFMVATLFAMTTHS-LTVLIAASAMQGMGTG-----VGGVMAR 118 LSD++G + ++L G+ I ++ HS ++LI A +QG G V V+AR Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 119 TLPRDLYEGTQLRHANSLLNMGILVSPLLAPLIGGLLDTLWNWRACYAFLLVLCAGVTFS 178 +P++ G S++ MG V P IGG++ +W ++ V F Sbjct: 131 YIPKE-NRGKAFGLIGSIVAMGEGV----GPAIGGMIAHYIHWSYLLLIPMITIITVPFL 185 Query: 179 MARWMPETR 187 M E R Sbjct: 186 MKLLKKEVR 194
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.0 bits (148), Expect = 2e-13 Identities = 23/116 (19%), Positives = 45/116 (38%), Gaps = 5/116 (4%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHT 114 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 4e-05 Identities = 30/142 (21%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 365 LRPRQLDDLTLAQAIRSLLREMELESRGIVSHLDWRIDETALSESQRVTLFRVCQEGLNN 424 LR ++LA + + ++L S L + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 425 IVKHA-----NASAVTLQGWQQDERLMLVIEDDGSGLPPGSQQ-QGFGLTGMRERVSALG 478 +KH + L+G + + + L +E+ GS +++ G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 479 G---TLTISCTHG-TRVSVSLP 496 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>cloacin#Cloacin signature. Length = 551 Score = 28.9 bits (64), Expect = 0.009 Identities = 13/47 (27%), Positives = 21/47 (44%) Query: 30 NGNGGGHGNNAANQGNNGNGHKGNAGQKTEHRKNGGKPDHVESDISY 76 N GGG G+ G +G+G+ G G GG V + +++ Sbjct: 44 NPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAF 90
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 42.3 bits (99), Expect = 6e-07 Identities = 43/180 (23%), Positives = 63/180 (35%), Gaps = 22/180 (12%) Query: 1 MSTPANF--NGQRPAIDANDAVMLLIDHQSGLFQTVGD--MPMPELRARAAALAKIATLC 56 M T ++ N D N AV+L+ D Q+ P+ EL A L Sbjct: 11 MPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQL 70 Query: 57 NMPVITTASVPQ-------------GPNGPLIPE----IHANAPYA-QYVARKGEINAWD 98 +PV+ TA GP P I AP V K +A+ Sbjct: 71 GIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFK 130 Query: 99 NADFVQAVKATGRKTLIIAGTITSVCMAFPAISAVAEGYKVFAVIDASGTYSKMAQEITM 158 + ++ ++ GR LII G + A A E K F V DA +S ++ + Sbjct: 131 RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEKHQMAL 190
>PERTACTIN#Pertactin signature. Length = 922 Score = 120 bits (302), Expect = 8e-30 Identities = 164/749 (21%), Positives = 289/749 (38%), Gaps = 90/749 (12%) Query: 230 TGDSSEGLRTGQSGSLIRLGDDATIETSGASSTGIYAASSSRTELGNNATITVNGASAHA 289 TG + G+ G+++ L ATI A + G + + Sbjct: 236 TGGRAAGV-AAMDGAIVHL-QRATIRRGDAPAGGAVPGGAVPGGAVPGG-FGPLLDGWYG 292 Query: 290 VYATNATVNLGDNATISVNSASKAASYSKAPAGLYALSRGAINLAGGAAITMAGDNSSES 349 V +++TV+L A V + A+ +S G+++ G I G Sbjct: 293 VDVSDSTVDL---AQSIVEAPQLGAAIRAGRGARVTVSGGSLSAPHGNVIETGGGARRFP 349 Query: 350 YAISTETGGIVDGS--SGGRFVIDGDIRAAGATAASGTLPQ--------------QNSTI 393 S + + G+ G + T A G Q + + Sbjct: 350 PPASPLSITLQAGARAQGRALLYRVLPEPVKLTLAGGAQGQGDIVATELPPIPGASSGPL 409 Query: 394 KLNMTDNSRWDGASYITSATAGTGVISVQMSDATWNMTSSSTLTDLTLNSGAIINFSH-- 451 + + +RW GA+ V S+ + +ATW MT +S + L L S ++F Sbjct: 410 DVALASQARWTGATRA--------VDSLSIDNATWVMTDNSNVGALRLASDGSVDFQQPA 461 Query: 452 EDGEPWQTLTINEDYVGNGGKLVFNTVLNDDDSETDRLQVLGNTSGNTFVAVNNIGGAGA 511 E G ++ L ++ G+G +F + D +D+L V+ + SG + V N G A Sbjct: 462 EAGR-FKVLMVDT-LAGSG---LFRMNVFADLGLSDKLVVMRDASGQHRLWVRNSGSEPA 516 Query: 512 QTIEGIEIVNVAGNSNGTFEKASR---IVAGAYDYNVVQKGKNWYLTSYIEPDEPIIPDP 568 + + +V S TF A++ + G Y Y + G + S + P P P Sbjct: 517 -SGNTMLLVQTPRGSAATFTLANKDGKVDIGTYRYRLAANGNGQW--SLVGAKAPPAPKP 573 Query: 569 VDPVIPDPVDPDPVDPVIPDPVIPDPVDPDPVDPEPVDPVIPDPVIPDIGQSDTPPITEH 628 P P P P P P P P P +P P P ++ + + Sbjct: 574 APQPGPQPGPQPPQPPQPPQP----PQPPQPPQRQPEAPAPQPPAGRELSAAANAAVNTG 629 Query: 629 QFRPEVGSYLANNYAANTLFMTRLHDRLGETQYTDMLTGEKKVTSLWMRNVGAHTRFNDG 688 + A + A L RLGE + G W R + ++ Sbjct: 630 GVGLASTLWYAESNA--------LSKRLGELRLNPDAGG------AWGRGFAQRQQLDNR 675 Query: 689 SGQLKTRINSYVLQLGGDLAQWSTDGLDRWHIGTMAGYANSQNRTQSSVSDYHSRGQVTG 748 +G+ + +LG D A + G RWH+G +AGY + D G Sbjct: 676 AGRRFDQ-KVAGFELGADHA-VAVAG-GRWHLGGLAGYTRGD---RGFTGD--GGGHTDS 727 Query: 749 YSVGLYGTWYANNIDRSGAYVDTWMLYNWFDN--KVMGQDQAA--EKYKSKGITASVEAG 804 VG Y T+ AN+ G Y+D + + +N KV G D A KY++ G+ S+EAG Sbjct: 728 VHVGGYATYIANS----GFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGVSLEAG 783 Query: 805 YSFRLGESAHQSYWLQPKAQVVWMGVQANDHREANGTLVKDDTAGNLLTRMGVKAYINGH 864 F ++L+P+A++ V +R ANG V+D+ ++L R+G++ Sbjct: 784 RRFAH----ADGWFLEPQAELAVFRVGGGAYRAANGLRVRDEGGSSVLGRLGLEV----G 835 Query: 865 NAIDDNKSREFQPFVEANWIHNTQPA-SVKMDDVS--SDMRGTKNIGELKVGIEGQITPR 921 I+ R+ QP+++A+ + A +V+ + ++ +++RGT+ EL +G+ + Sbjct: 836 KRIELAGGRQVQPYIKASVLQEFDGAGTVRTNGIAHRTELRGTR--AELGLGMAAALGRG 893 Query: 922 LNVWGNVAQQVGDQGYSNTQGLLGVKYSF 950 +++ + G + G +YS+ Sbjct: 894 HSLYASYEYSKGPKLAMPWTFHAGYRYSW 922
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 242 bits (620), Expect = 9e-86 Identities = 82/154 (53%), Positives = 110/154 (71%) Query: 5 AIYPGTFDPITNGHLDIVTRATQMFDHVILAIAASPGKKPMFTLDERVALAQKATAHLGN 64 AIYPG+FDPIT GHLDI+ R ++FD V +A+ +P K+PMF++ ER+ KA AHL N Sbjct: 3 AIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPN 62 Query: 65 VEVVGFSDLMANFARDRQANILIRGLRAVADFEYEMQLAHMNRHLMPQLESVFLMPSKEW 124 +V F L N+AR RQA ++RGLR ++DFE E+Q+A+ N+ L LE+VFL S E+ Sbjct: 63 AQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFLTTSTEY 122 Query: 125 SFISSSLVKEVARHQGDVTHFLPDNVHQALMDKL 158 SF+SSSLVKEVAR G+V HF+P +V AL D+ Sbjct: 123 SFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQF 156
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 99.5 bits (248), Expect = 3e-26 Identities = 75/348 (21%), Positives = 125/348 (35%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLNI 47 +VTG AGFIG ++ K L + G ++ +DNL D +++ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMSGEELGDIEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + G E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLF---ASGHFERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 AVNL------------WFLESGKSG-------IFNLGTGRAESFQAVADATLAY-HKKGS 258 + W +E+G ++N+G A + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRNA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 7e-08 Identities = 25/196 (12%), Positives = 62/196 (31%), Gaps = 21/196 (10%) Query: 45 RDQLKSIQADIAAKERDVRQQQQQRASLLAQLKAQEEAISAAARKLRETQSTLDQLNAQI 104 ++ + + Q +L +E S + + + LD+ A+ Sbjct: 157 SRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAER 216 Query: 105 DEMNASIAKLEQQKASQERNLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYFGYLN 164 + A I + E ++ L + + ++ Q + ++A Sbjct: 217 LTVLARINRYENLSRVEKSRLDD-FSSLLHKQAIAKHAVL-----EQENKYVEA-----V 265 Query: 165 QARQETIAELKQTREQVATQKAELEEKQSQQQTLLYEQRAQ-QAKLEQARNERKKTLAGL 223 + ++L+Q ++ + K E + + + ++ Q + E K Sbjct: 266 NELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE-- 323 Query: 224 ESSIQQGQQQLSELRA 239 +QQ S +RA Sbjct: 324 -------RQQASVIRA 332
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 234 bits (598), Expect = 2e-82 Identities = 91/153 (59%), Positives = 118/153 (77%), Gaps = 4/153 (2%) Query: 3 EQNNTEMAFQIQRIYTKDVSFEAPNAPHVFQKDWQPEVKLDLDTASSQLADDVYEVVLRV 62 Q + QIQRIY KDVSFEAPN PH+FQ+DW+P++ DL T + Q+ DD+YEV L + Sbjct: 12 TQATQQPVLQIQRIYVKDVSFEAPNLPHIFQQDWEPKLSFDLSTEAKQVGDDLYEVCLNI 71 Query: 63 TVTASLGEE--TAFLCEVQQAGIFSISGIEGTQMAHCLGAYCPNILFPYARECITSLVSR 120 +V ++ AF+CEV+QAG+F+ISG+E QMAHCL + CPN+LFPYARE ++SLV+R Sbjct: 72 SVETTMESSGDVAFICEVKQAGVFTISGLEEMQMAHCLTSQCPNMLFPYARELVSSLVNR 131 Query: 121 GTFPQLNLAPVNFDALFMNYL--QQQAGEGTEE 151 GTFP LNL+PVNFDALFM+YL Q+QA + TEE Sbjct: 132 GTFPALNLSPVNFDALFMDYLQRQEQAEQTTEE 164
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.028 Identities = 21/87 (24%), Positives = 30/87 (34%), Gaps = 13/87 (14%) Query: 8 MTVI---GAGSYGTALAITLARNGHQVVLWGHD---PKHIATLEHDRCNVAFLPDVPFPD 61 M + AG G ++ L GHQVV G D + +L+ R + P F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVV--GIDNLNDYYDVSLKQARLELLAQPGFQF-- 56 Query: 62 TLHLESDLATALAASRNILVVVPSHVF 88 + DLA + VF Sbjct: 57 ---HKIDLADREGMTDLFASGHFERVF 80
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 70.2 bits (172), Expect = 6e-17 Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 1382 VENKMSGGIASAMAMAGLPQAYAPGANMTSIAGGTFNGESAVAIGI-SMVSESGGWVYKL 1440 + ++ G+A+ A++ L Q G S A G + ++A+AIG+ S +++ + Sbjct: 1 LSKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGV 60 Query: 1441 QGTSNSQGDYSAAIGAGFQW 1460 + + G S G+++ Sbjct: 61 AFNTYN-GGMSYGASVGYEF 79
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 52.9 bits (127), Expect = 2e-09 Identities = 35/106 (33%), Positives = 53/106 (50%), Gaps = 16/106 (15%) Query: 3 IATAGHVDHGKTTLLQAI---TGV------------NADRLPEEKKRGMTIDLGYAYWPQ 47 I HVD GKTTL +++ +G D E++RG+TI G + Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 48 PDGRVLGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTR 93 + +V ID PGH FL+ + + +D A+L+++ DGV AQTR Sbjct: 66 ENTKV-NIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTR 110
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (293), Expect = 1e-33 Identities = 43/124 (34%), Positives = 64/124 (51%), Gaps = 11/124 (8%) Query: 108 LNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEY--PKTAVNVVGYTDSTGSHDLNMRLS 165 + ++V F+ + ATLKP G L + L +V V+GYTD GS N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASSLITQGVDASRIRTSGMGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A +I GMG +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SPLQ 220 ++ Sbjct: 335 KGIK 338
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 8e-05 Identities = 20/52 (38%), Positives = 26/52 (50%), Gaps = 5/52 (9%) Query: 76 VAPDALRHGIGKALL----EYVQQR-FPLLSLEVYQKNQSAVNFYHALGFRI 122 VA D + G+G ALL E+ ++ F L LE N SA +FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 30.1 bits (68), Expect = 0.022 Identities = 23/194 (11%), Positives = 57/194 (29%), Gaps = 40/194 (20%) Query: 12 TGLLLLLALAFVLFYEAINGFHDTANAVATVIY------TRAMRSQLAVVMAAVFNFFGV 65 L++AL+ +L + F + + ++A+ + V+ F Sbjct: 30 VSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYLCFP 89 Query: 66 LLGGLSVAYAIVHML-------------------PTDLLLNMGSAHGLAMVFSMLLAAII 106 LL ++ H++ P + + S L +L ++ Sbjct: 90 LLTVAALMAIASHVVQYGFLISGEAIKPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVL 149 Query: 107 WNLGTWYFGLPASSSHTLIGAIIGIGLTNAMMTGTSVVDALNIPKVINIFGSLIISPIVG 166 ++ W + ++ + T + T ++ + L++ VG Sbjct: 150 LSILIWIIIKG------NLVTLLQLP-TCGIECITPLLGQI--------LRQLMVICTVG 194 Query: 167 LVFAGGLIFLLRRY 180 V + Y Sbjct: 195 FVVISIADYAFEYY 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 4e-18 Identities = 70/413 (16%), Positives = 136/413 (32%), Gaps = 82/413 (19%) Query: 3 KMKRHLVWWGAGILVAVAAIAWWMLRPAGIPEGFAASNGRI--EATEVDIATKIAGRIDT 60 + LV + + V A +L E A +NG++ +I + Sbjct: 54 SRRPRLVAY-FIMGFLVIAFILSVLGQV---EIVATANGKLTHSGRSKEIKPIENSIVKE 109 Query: 61 ILVSEGQFVRQGEVLAKMDTRV----------------LQEQRLEAI------------- 91 I+V EG+ VR+G+VL K+ L++ R + + Sbjct: 110 IIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELK 169 Query: 92 -----------------------AQIKEAESAVAAARALLEQRQSEMRAAQSVVKQREAE 128 Q ++ L+++++E + + + E Sbjct: 170 LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENL 229 Query: 129 LDSVSKRHVRSRSLSQRGAVSVQQLDDDRAAAESARAALETAKAQVSAAKAAIEAARTSI 188 R SL + A++ + + A L K+Q+ ++ I +A+ Sbjct: 230 SRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEY 289 Query: 189 IQ-------------AQTRVEAAQATERRIVADID--DSELKAPRDGRV-QYRVAEPGEV 232 QT T + S ++AP +V Q +V G V Sbjct: 290 QLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 233 LSAGGRVLNMVDLSDVY-MTFFLPTEQAGLLKIGGEARLVLDAAPDLRIPATISFVASVA 291 ++ ++ +V D +T + + G + +G A + ++A P R V V Sbjct: 350 VTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYG---YLVGKVK 406 Query: 292 QFTPKTVETHDERLKLMFRVKARIPPELLRQHLEYV--KTGLPGMAWVRLDER 342 +E D+RL L+F V I L + + +G+ A ++ R Sbjct: 407 NINLDAIE--DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMR 457
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 48.0 bits (114), Expect = 2e-08 Identities = 43/171 (25%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPVTPFEIMMAKV-WSMGLVVLVVSGLSLMLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G + +V LG + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG---IGVVAAALGY-TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLMILVLLPLQMLSGGSTPRESMPQAVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGLSIVWPQFLTLLAIGGVFFL-IALLRFR 367 +P +H + L + I+ + + + I FFL ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 32.7 bits (74), Expect = 6e-04 Identities = 25/93 (26%), Positives = 44/93 (47%), Gaps = 6/93 (6%) Query: 30 RRASWLAGRVLLSRALSPL---PEMVYGEQGKPAFSAGTPLWFNLSHSGDTIALLLSDEG 86 R+A LAGR+ AL + G++ +P + G L+ ++SH T ++S + Sbjct: 46 RKAEHLAGRIAAVHALREVGVRTVPGMGDKRQPLWPDG--LFGSISHCATTALAVISRQ- 102 Query: 87 EVGCDIEVIRPRDNWRSLANAVFSLGEHAEMEA 119 +G DIE I + LA ++ E ++A Sbjct: 103 RIGIDIEKIMSQHTATELAPSIIDSDERQILQA 135
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 48.7 bits (116), Expect = 2e-08 Identities = 75/403 (18%), Positives = 138/403 (34%), Gaps = 42/403 (10%) Query: 13 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHD--AMGFSAFWAGLIISLQYFATLLSR 70 ++ N ++ I+ + IGL + VLPG + D G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 71 PHAGRYADVLGPKKIVVFGLCGCFLSGLGYLLADIASAWPLISLLLLGLGRVILGI-GQS 129 P G +D G + +++ L G + + Y + A L +L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPF-----LWVLYIGRIVAGITGAT 112 Query: 130 FAGTGSTLWGVGVVGSLHIGRVISWNGIVTYGAMAMGAPLGVLCYAWGGLQGLALTVMGV 189 A G+ + + R + M G LG L G Sbjct: 113 GAVAGAYIADITDGDER--ARHFGFMSACFGFGMVAGPVLGGLM----GGFSPHAPFFAA 166 Query: 190 ALLAILLAL----------PRPSVKANKGKPLPFRAVLGRVWLYGMALALA-----SAGF 234 A L L L + P + + +A +A Sbjct: 167 AALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVG 226 Query: 235 GVIATFITLFYDAK-GWDGAAFALTLFSVAFVGT---RLLFPNGINRLGGLNVAMICFGV 290 V A +F + + WD ++L + + + ++ RLG M+ Sbjct: 227 QVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIA 286 Query: 291 EIIGLLLVGTAAMPWMAKIGVLLTGMGFSLVFPALGVVAVKAVPPQNQGAALATYTVFMD 350 + G +L+ A WMA ++L + PAL + + V + QG + Sbjct: 287 DGTGYILLAFATRGWMAFPIMVLLA-SGGIGMPALQAMLSRQVDEERQGQLQGSLAALTS 345 Query: 351 MSLGVTGPLAGLVMTWAGVPV----IYLAAAGLVAMALLLTWR 389 ++ + GPL + A + ++A A L + L R Sbjct: 346 LT-SIVGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF04183#IucA / IucC family Length = 580 Score = 27.9 bits (62), Expect = 0.038 Identities = 17/91 (18%), Positives = 28/91 (30%), Gaps = 14/91 (15%) Query: 121 LGQILDVHVFNRLRQNRRWWLAPTASTLFGNISDTLAFFFIAFWRSPDAFMAEHWMEIAL 180 LG I + L+ + +TL + + AE W+ Sbjct: 347 LGVIWRENPCRWLKPDES---PVLMATLMECDENNQPL--AGAYIDRSGLDAETWLT--- 398 Query: 181 VDYCFKVLISIIFFLPMYGVLL-----NMLL 206 V++ + L YGV L N+ L Sbjct: 399 -QLFRVVVVPLYHLLCRYGVALIAHGQNITL 428
>PF01206#SirA family protein Length = 76 Score = 101 bits (254), Expect = 2e-32 Identities = 28/72 (38%), Positives = 42/72 (58%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQTGETLLIIADDPATTRDIPGFCTFMEHDLLAQET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F H+LL Q+ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 EGLPYRYLLRKA 80 E Y + L++A Sbjct: 65 EDGTYHFRLKRA 76
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 30.2 bits (68), Expect = 0.040 Identities = 17/78 (21%), Positives = 34/78 (43%), Gaps = 3/78 (3%) Query: 336 AEERRAPIERFIDRFSRIYTPVIMVIALLVTLIPPLMFDGGWQEWIYKGLTLLLIGCPCA 395 E++ P E S+I ++ + +L + P+ F GG IY+ ++ ++ A Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVS---A 477 Query: 396 LVISTPAAITSGLAAAAR 413 + +S A+ A A Sbjct: 478 MALSVLVALILTPALCAT 495
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 26.7 bits (59), Expect = 0.026 Identities = 6/29 (20%), Positives = 16/29 (55%) Query: 7 FFIIIIALIVVAASFRFVQQRREKAANEA 35 +++I AA ++F++Q+ K ++ Sbjct: 173 ALMVLIQSTSEAARYKFIEQQIGKRVDKT 201
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 32.4 bits (73), Expect = 0.004 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 275 RTPISGDYRGYQVFSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 331 R P+ G+ R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 332 YAYADRSEYLGDPDFVKVPWQA 353 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 5e-05 Identities = 18/92 (19%), Positives = 34/92 (36%), Gaps = 16/92 (17%) Query: 55 VACIDDIVVGHLSIQVTQRPRRSHVADFGICVDARWHNRGIASALIRTMID------MCD 108 + +++ +G + I+ + + D + D R G+ +AL+ I+ C Sbjct: 69 LYYLENNCIGRIKIRSNWN-GYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVERIELTVFVDNEPAVAVYKKYGFEIEG 140 L + I N A Y K+ F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.5 bits (68), Expect = 0.013 Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 3/50 (6%) Query: 268 FAADESVGVLEYVNDDGVTVKEEVKPETGDYGRVYDALYQTLTVGTPNYV 317 ++AD+ ++Y N DG + K + G+ Y +YQ GT NY+ Sbjct: 1052 YSADDLSNYVDYANADGNKLSNTCK---LNPGKYYLCVYQFENSGTGNYI 1098
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 164 bits (417), Expect = 3e-55 Identities = 43/141 (30%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVLALQDQGFENINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L+ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPASGFSVRDLYEAILELF 152 + + + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.5 bits (63), Expect = 0.031 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKNQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 IAKTCPK----ACVGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 ++K + V + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.008 Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 1/60 (1%) Query: 509 SSAPVQA-VAPAGAGTPVTAPLAGNIWKVIATEGQTVAEGDVLLILEAMKMETEIRAAQA 567 A + +G + + ++I EG++V +GDVLL L A+ E + Q+ Sbjct: 82 IVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS 141
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 95.8 bits (238), Expect = 6e-27 Identities = 38/205 (18%), Positives = 68/205 (33%), Gaps = 20/205 (9%) Query: 7 ESLPTRMRILRAARQCFAENGFHSTSMKTICKASDMSPGTLYHHFPSKEALIEAIILEDQ 66 E+ TR IL A + F++ G STS+ I KA+ ++ G +Y HF K L I + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 67 ERALTHFREPLEGVG-----LVDYLVESTIAVTREDCAQRALVVEIMAEGMR---NPQVA 118 E ++ ++ + T + +R L+ I + V Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 119 EMLTNKYHTIIASLVARFNDAQAKGEIGADVDKEMAARLLLATTYGVL-------SDSSS 171 + N + + AD+ AA ++ G++ Sbjct: 128 QAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDL 187 Query: 172 AENARHVSFATTLRTMLTGLLKCNS 196 + AR +L L C + Sbjct: 188 KKEARDYV-----AILLEMYLLCPT 207
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.1 bits (86), Expect = 5e-05 Identities = 17/94 (18%), Positives = 32/94 (34%), Gaps = 7/94 (7%) Query: 149 IAGARGTPVYAAGA--GKVVYVGNQLRGYGNLIMIKHNEDYITAYAHNDTMLVNNGQSVK 206 + + + V +L G IK E+ I ++V G+SV+ Sbjct: 65 MGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIV-----KEIIVKEGESVR 119 Query: 207 AGQKIATMGSTDAASVRLHFQIRYRATAIDPLRY 240 G + + + A + L Q ++ RY Sbjct: 120 KGDVLLKLTALGAEADTLKTQSSLLQARLEQTRY 153
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 97.3 bits (242), Expect = 4e-28 Identities = 53/183 (28%), Positives = 78/183 (42%), Gaps = 17/183 (9%) Query: 1 MNKMLLAGSAGIVLLSAAASPVWADDNASTFSLGYAQSH-TNHAGTLRGVRLANNYEMSP 59 M K+ SA +L+ A A ST + GYAQS + G L YE Sbjct: 1 MKKIACL-SALAAVLAFTAGTSVAA--TSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDN 57 Query: 60 D-WGLTTSFAWLNGSQRYSDESSNGRVTTRYYSLLAGPSWKINNQLSLYSQVGPVLLHQR 118 G+ SF + S SS +YY + AGP+++IN+ S+Y VG + Sbjct: 58 SPLGVIGSFTYTEKS---RTASSGDYNKNQYYGITAGPAYRINDWASIYGVVGVGYGKFQ 114 Query: 119 DH---GINESDSKVGYGYSAGVAYTPVSNVAINLGYEGADFDATHNSGSLNSNGFNLGVG 175 S G+ Y AG+ + P+ NVA++ YE + S++ + GVG Sbjct: 115 TTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQS------RIRSVDVGTWIAGVG 168 Query: 176 YRF 178 YRF Sbjct: 169 YRF 171
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 633 bits (1635), Expect = 0.0 Identities = 230/856 (26%), Positives = 380/856 (44%), Gaps = 66/856 (7%) Query: 19 SQATEFNASLLDSGNLSNVDLTAFSREGYVAPGNYILDIWLNDQPVREQYPVRVVPVAGR 78 S FN L + DL+ F + PG Y +DI+LN+ + + V Sbjct: 44 SAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRD-VTFNTGDSE 102 Query: 79 DAAVICVTTDMVAMLGLKDKIIHGLKPVTGIPDGQCLELRSA--DSQVRYSAENQRLTFI 136 V C+T +A +GL + + + D C+ L S D+ + QRL Sbjct: 103 QGIVPCLTRAQLASMGLNTA---SVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLT 159 Query: 137 IPQAWMRYQDPDWVPPSRWSDGVTAGLLDYNLMVNRYMPQQGETSTSYSLYGTAGFNLGA 196 IPQA+M + ++PP W G+ AGLL+YN N + G S L +G N+GA Sbjct: 160 IPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGA 219 Query: 197 WRLRSDYQYSRFDS-GQGASQSDFYLPQTYLFRALPALRSKLTLGQTYLSSAIFDSFRFA 255 WRLR + +S S S++ + T+L R + LRS+LTLG Y IFD F Sbjct: 220 WRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFR 279 Query: 256 GLTLASDERMLPPSLQGYAPKISGIANSNAQVTVSQNGRILYQTRVSPGPFELPDLSQ-N 314 G LASD+ MLP S +G+AP I GIA AQVT+ QNG +Y + V PGPF + D+ Sbjct: 280 GAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAG 339 Query: 315 ISGNLDVSVRESDGSVRTWQVNTASVPFMARQGQVRYKVAAGRPLYGGTHNNSTVSPDFL 374 SG+L V+++E+DGS + + V +SVP + R+G RY + AG G N P F Sbjct: 340 NSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSG---NAQQEKPRFF 396 Query: 375 LGEATWGAFNNTSLYGGLIASTGDYQSAALGIGQNMGLLGALSADVTRSDARLPHGQKQS 434 G ++YGG + Y++ GIG+NMG LGALS D+T++++ LP + Sbjct: 397 QSTLLHGLPAGWTIYGGTQLA-DRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHD 455 Query: 435 GYSYRINYAKTFDKTGSTLAFVGYRFSDRHFLSMPEYLQRRATDGGD------------- 481 G S R Y K+ +++G+ + VGYR+S + + + R Sbjct: 456 GQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKF 515 Query: 482 ------AWHEKQSYTVTYSQSVPVLNMSAALSVSRLNYWNAQ-SNNNYMLSFNKVFSLGE 534 A++++ +T +Q + + LS S YW + + N F Sbjct: 516 TDYYNLAYNKRGKLQLTVTQQLG-RTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF---- 570 Query: 535 LQGLSASVSFARNQYTGG-GSQNQVYATISIPWGDSR-----------QVSYSVQKDNRG 582 + ++ ++S++ + G + ++IP+ SYS+ D G Sbjct: 571 -EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNG 629 Query: 583 GLQQTVNYSD--FHNPDTTWNISAGHNRYDTGSN-SSFSGSVQSRLPWGQAAADATLQPG 639 + + + ++++ G+ G++ S+ ++ R +G A + Sbjct: 630 RMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDD 689 Query: 640 QYRSLGLSWYGSVTATAHGAAFSQSMAGNEPRMMIDTGDVAGVPVNGNSGV-TNRFGVGV 698 + L G V A A+G Q + N+ +++ V +GV T+ G V Sbjct: 690 -IKQLYYGVSGGVLAHANGVTLGQPL--NDTVVLVKAPGAKDAKVENQTGVRTDWRGYAV 746 Query: 699 VSAGSSYRRSDISVDVAALPEDVDVSSSVISQVLTEGAVGYRKIDASQGEQVLGHIRLAD 758 + + YR + +++D L ++VD+ ++V + V T GA+ + A G ++L + + Sbjct: 747 LPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HN 805 Query: 759 GASPPFGALVVSGKTGRTAGMVGDGGLAYLTGLSGEDRRTLNVSW--DGRVQCRLTLPET 816 PFGA+V S +++G+V D G YL+G+ + V W + C Sbjct: 806 NKPLPFGAMVTSES-SQSSGIVADNGQVYLSGM--PLAGKVQVKWGEEENAHCVANYQLP 862 Query: 817 VTLSRGPL---LLPCR 829 + L CR Sbjct: 863 PESQQQLLTQLSAECR 878
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 85.2 bits (211), Expect = 6e-21 Identities = 68/297 (22%), Positives = 116/297 (39%), Gaps = 48/297 (16%) Query: 1 MQIIITGGGGFLGQKLASALLNSSL------AFNELLLVDLKMPARLS--DSPRLRCLEA 52 M+ ++TG GF+G ++ LL + N+ V LK ARL P + + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQ-ARLELLAQPGFQFHKI 59 Query: 53 DLT-QPGVLENVITANTSVVYHLAA-------IVSSHAEDDFDLGWKVNLDLTRQLLEAC 104 DL + G+ + + + V+ + + HA D NL +LE C Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD------SNLTGFLNILEGC 113 Query: 105 RRQPQKIRFVFSSSLAVYGG--TLPECVTDTTALTPRSSYGAQKAACELLVNDYTRKGYV 162 R + +++SS +VYG +P D+ P S Y A K A EL+ + Y+ + Sbjct: 114 RHNKIQ-HLLYASSSSVYGLNRKMPFSTDDSVD-HPVSLYAATKKANELMAHTYSHLYGL 171 Query: 163 DGLALRLPTICVRPGKPNRAASSFVSAIIREPLQGE--------------TTICPVSESL 208 LR T+ G+P+ A F A+ L+G+ T I ++E++ Sbjct: 172 PATGLRFFTVYGPWGRPDMALFKFTKAM----LEGKSIDVYNYGKMKRDFTYIDDIAEAI 227 Query: 209 RLWISSPATVIHNLSLAATLPAPGEA--SSINLPGIS-VTVGEMLETLRQAGGQAAR 262 ++ PA A N+ S V + + ++ L A G A+ Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 80.3 bits (198), Expect = 1e-18 Identities = 67/387 (17%), Positives = 144/387 (37%), Gaps = 48/387 (12%) Query: 16 FLDLINLFIASVAFPAMSVDLHTSISALAWVSNGYIAGLTLIIPFSAFLSRYLGARRLII 75 F ++N + +V+ P ++ D + ++ WV+ ++ ++ LS LG +RL++ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 76 FSLILFSVAAAAAGFADSLHS-LVFWRIVQGVGGGLLIPVGQALTWQQFKPHERAGVSSV 134 F +I+ + S S L+ R +QG G + + + R + Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 135 VMMVALLAPACSPAIGGLLVETCGWRWIFF-----------------------ATLPVAV 171 + + + PAIGG++ W ++ + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKG 203 Query: 172 LTLLLAYCWLNVASTTMASARLLHL-----------------PLLTDRLLRFAMIVYLCV 214 + L+ + TT S L + P + L + + + Sbjct: 204 IILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVL 263 Query: 215 PGMFIGISVVGM-----FYLQNVAQLSPAAAGS-LMLPWSIASFVAIMFTGRYFNRLGPR 268 G I +V G + +++V QLS A GS ++ P +++ + G +R GP Sbjct: 264 CGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPL 323 Query: 269 PLIIVGCLLQAAGILLLTNVTPATSHRVLMMIFALMGAGGSLCSSTAQSGAFLTIARRDM 328 ++ +G + L + + TS + ++I ++G G S + + ++ +++ Sbjct: 324 YVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVISTIVSSSLKQQEA 382 Query: 329 PDASALWNLNRQLSFFLGATLLTLLLN 355 +L N LS G ++ LL+ Sbjct: 383 GAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 576 bits (1485), Expect = 0.0 Identities = 170/540 (31%), Positives = 271/540 (50%), Gaps = 57/540 (10%) Query: 4 HILLARVLACAALVLVAPGYSSE----KIPVTGSGFVAKDDSLRTFFDAMALQLKEPVIV 59 H RVL L+L + ++ E IP +VAK +SLR V+V Sbjct: 6 HSFFKRVLTGTLLLLSSYSWAQELDWLPIPYV---YVAKGESLRDLLTDFGANYDATVVV 62 Query: 60 SKMAARKKITGNFEFHDPNALLEKLSLQLGLIWYFDGQAIYIYDASEMRNAVVSLRNVSL 119 S K++G FE +P L+ ++ L+WY+DG +YI+ SE+ + ++ L+ Sbjct: 63 SD-KINDKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEA 121 Query: 120 NEFNNFLKRSGLYNKNYPLRGDNRKGTFYVSGPPVYVDMVVNAATMMDKQND--GIELGR 177 E L+RSG++ + R D YVSGPP Y+++V A +++Q + G Sbjct: 122 AELKQALQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGA 181 Query: 178 QKIGVMRLNNTFVGDRTYNLRDQKMVIPGIATAIERLLQGEEQPLGNIVSSEPPAMPAFS 237 I + L DRT + RD ++ PG+AT ++R+L + + P Sbjct: 182 LAIEIFPLKYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIP------ 235 Query: 238 ANGEKGKAANYAGGMSLQEALKQNAAAGNIKIVAYPDTNSLLVKGTAEQVHFIEMLVKAL 297 Q A + +A A ++ A P N+++V+ + E++ + L+ AL Sbjct: 236 -----------------QAATRASAQA---RVEADPSLNAIIVRDSPERMPMYQRLIHAL 275 Query: 298 DVAKRHVELSLWIVDLNKSDLERLGTSWSGSI-----------TIGDKLGVSLNQASIST 346 D +E++L IVD+N L LG W I T GD+ ++ N A S Sbjct: 276 DKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSL 335 Query: 347 LDG---SRFIAAVNALEEKKQATVVSRPVLLTQENVPAIFDNNRTFYTKLIGERNVALEH 403 +D +A VN LE + A VVSRP LLTQEN A+ D++ T+Y K+ G+ L+ Sbjct: 336 VDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDHSETYYVKVTGKEVAELKG 395 Query: 404 VTYGTMIRVLPRFSADG---QIEMSLDIEDGNDKTPQSDTTTSVDALPEVGRTLISTIAR 460 +TYGTM+R+ PR G +I ++L IEDGN Q ++ ++ +P + RT++ T+AR Sbjct: 396 ITYGTMLRMTPRVLTQGDKSEISLNLHIEDGN----QKPNSSGIEGIPTISRTVVDTVAR 451 Query: 461 VPHGKSLLVGGYTRDANTDTVQSIPFLGKLPLIGSLFRYSSKNKSNVVRVFMIEPKEIVD 520 V HG+SL++GG RD + + +P LG +P IG+LFR S+ VR+F+IEP+ I + Sbjct: 452 VGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRIIDE 511
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 604 bits (1558), Expect = 0.0 Identities = 371/372 (99%), Positives = 371/372 (99%) Query: 1 MIPGSTSGISFSRILSRQTSHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSA 60 MIPGSTSGISFSRILSRQ SHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSA Sbjct: 1 MIPGSTSGISFSRILSRQASHQDATQHTDAQQAEIQQAAEDSSPGAEVQKFVQSTDEMSA 60 Query: 61 ALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFP 120 ALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFP Sbjct: 61 ALAQFRNRRDYEKKSSNLSNSFERVLEDEALPKAKQILKLISVHGGALEDFLRQARSLFP 120 Query: 121 DPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLS 180 DPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLS Sbjct: 121 DPSDLVLVLRELLRRKDLEEIVRKKLESLLKHVEEQTDPKTLKAGINCALKARLFGKTLS 180 Query: 181 LKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSR 240 LKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSR Sbjct: 181 LKPGLLRASYRQFIQSESHEVEIYSDWIASYGYQRRLVVLDFIEGSLLTDIDANDASCSR 240 Query: 241 LEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSL 300 LEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSL Sbjct: 241 LEFGQLLRRLTQLKMLRSADLLFVSTLLSYSFTKAFNAEESSWLLLMLSLLQQPHEVDSL 300 Query: 301 LADIIGLNALLLSHKEHASFLQIFYQVCKAIPSSLFYEEYWQEELLMALRSMTDIAYKHE 360 LADIIGLNALLLSHKEHASFLQIFYQVCKAIPSSLFYEEYWQEELLMALRSMTDIAYKHE Sbjct: 301 LADIIGLNALLLSHKEHASFLQIFYQVCKAIPSSLFYEEYWQEELLMALRSMTDIAYKHE 360 Query: 361 MAEQRRTIEKLS 372 MAEQRRTIEKLS Sbjct: 361 MAEQRRTIEKLS 372
>SSPAKPROTEIN#Invasion protein B family signature. Length = 133 Score = 206 bits (525), Expect = 3e-72 Identities = 43/133 (32%), Positives = 76/133 (57%) Query: 1 MQHLDIAELVRSALEVSGCDPSLIGGIDSHSTIVLDLFALPSICISVKDDDVWIWAQLGA 60 M ++++ +LVR +L GC PS+I +DSHS I + L ++P+I I++ ++ V +WA A Sbjct: 1 MSNINLVQLVRDSLFTIGCPPSIITDLDSHSAITISLDSMPAINIALVNEQVMLWANFDA 60 Query: 61 DSMVVLQQRAYEILMTIMEGCHFARGGQLLLGEQNGELTLKALVHPDFLSDGEKFSTALN 120 S V LQ AY IL ++ ++ + L + L L+ ++ D++ DG F+ L+ Sbjct: 61 PSDVKLQSSAYNILNLMLMNFSYSINELVELHRSDEYLQLRVVIKDDYVHDGIVFAEILH 120 Query: 121 GFYNYLEVFSRSL 133 FY +E+ + L Sbjct: 121 EFYQRMEILNGVL 133
>SSPAMPROTEIN#Salmonella surface presentation of antigen gene type M signature. Length = 147 Score = 167 bits (423), Expect = 2e-56 Identities = 141/147 (95%), Positives = 143/147 (97%) Query: 1 MHSLTRIKVLQRRCTVFHSQCESILLRYQDEDRGLQAEEEAILEQIAGLKLLLDTLRAEN 60 MHSLTRIKVLQRRCTVFHSQCESILLRYQDEDR LQ EEEAI+EQIAGLKLLLDTLRAEN Sbjct: 1 MHSLTRIKVLQRRCTVFHSQCESILLRYQDEDRRLQVEEEAIVEQIAGLKLLLDTLRAEN 60 Query: 61 RQLSREEIYTLLRKQSIVRRQIKDLELQIIQIQEKRSELEKKREEFQKKSKYWLRKEGNY 120 RQLSREEIY LLRKQSIVRRQIKDLELQIIQIQEKRSELEKKREEFQ+KSKYWLRKEGNY Sbjct: 61 RQLSREEIYALLRKQSIVRRQIKDLELQIIQIQEKRSELEKKREEFQEKSKYWLRKEGNY 120 Query: 121 QRWIIRQKRHYIQREIQQEEAESEEII 147 QRWIIRQKR YIQREIQQEEAESEEII Sbjct: 121 QRWIIRQKRLYIQREIQQEEAESEEII 147
>SSPANPROTEIN#Salmonella invasion protein InvJ signature. Length = 336 Score = 598 bits (1542), Expect = 0.0 Identities = 331/336 (98%), Positives = 332/336 (98%) Query: 1 MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSDHKKDRDYGDAFVMHKETAL 60 MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYS KKDRDYGDAFVMHKETAL Sbjct: 1 MGDVSAVSSSGNILLPQQDEVGGLSEALKKAVEKHKTEYSGDKKDRDYGDAFVMHKETAL 60 Query: 61 PVLLAAWRHGAPAKSEHHNGNVSGLHHNGKGELRIAEKLLKVTAEKSVGLISAEAKVDKS 120 P+LLAAWRHGAPAKSEHHNGNVSGLHHNGK ELRIAEKLLKVTAEKSVGLISAEAKVDKS Sbjct: 61 PLLLAAWRHGAPAKSEHHNGNVSGLHHNGKSELRIAEKLLKVTAEKSVGLISAEAKVDKS 120 Query: 121 AALLSPKNRPLESVSGKKLSADLKAVESVSEVTDNATGISDDNIKALPGDNKAIAGEGVR 180 AALLS KNRPLESVSGKKLSADLKAVESVSEVTDNATGISDDNIKALPGDNKAIAGEGVR Sbjct: 121 AALLSSKNRPLESVSGKKLSADLKAVESVSEVTDNATGISDDNIKALPGDNKAIAGEGVR 180 Query: 181 KEGAPLARDVAPARMAAANTGKPEDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA 240 KEGAPLARDVAPARMAAANTGKPEDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA Sbjct: 181 KEGAPLARDVAPARMAAANTGKPEDKDHKKVKDVSQLPLQPTTIADLSQLTGGDEKMPLA 240 Query: 241 AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLH 300 AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLH Sbjct: 241 AQSKPMMTIFPTADGVKGEDSSLTYRFQRWGNDYSVNIQARQAGEFSLIPSNTQVEHRLH 300 Query: 301 DQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEEDDA 336 DQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEEDDA Sbjct: 301 DQWQNGNPQRWHLTRDDQQNPQQQQHRQQSGEEDDA 336
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 538 bits (1386), Expect = 0.0 Identities = 302/303 (99%), Positives = 302/303 (99%) Query: 1 MSLRVRQIDRREWLLAQTATECQRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWL 60 MSLRVRQIDRREWLLAQTATECQRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWL Sbjct: 1 MSLRVRQIDRREWLLAQTATECQRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWL 60 Query: 61 EHVSPALAGAAVSAGAEHLVVPWLAATERPFELPVPHLSCRRLCVENPVPGSALPEGKLL 120 EHVSPALAGAAVSAGAEHLVVPWLAATERPFELPVPHLSCRRLCVENPVPGSALPEGKLL Sbjct: 61 EHVSPALAGAAVSAGAEHLVVPWLAATERPFELPVPHLSCRRLCVENPVPGSALPEGKLL 120 Query: 121 HIMSDRGGLWFEHLPELPAVGGGRPKMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTS 180 HIMSDRGGLWFEHLPELPAVGGGRPKMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTS Sbjct: 121 HIMSDRGGLWFEHLPELPAVGGGRPKMLRWPLRFVIGSSDTQRSLLGRIGIGDVLLIRTS 180 Query: 181 RAEVYCYAKKLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYR 240 RAEVYCYAKKLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYR Sbjct: 181 RAEVYCYAKKLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEFVLYR 240 Query: 241 KNVTLAELETMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESG 300 KNVTLAELE MGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESG Sbjct: 241 KNVTLAELEAMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIHEWLSESG 300 Query: 301 NGE 303 NGE Sbjct: 301 NGE 303
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 303 bits (777), Expect = e-107 Identities = 224/224 (100%), Positives = 224/224 (100%) Query: 1 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS Sbjct: 1 MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLS 60 Query: 61 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL Sbjct: 61 MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL 120 Query: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL Sbjct: 121 KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL 180 Query: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT 224 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT Sbjct: 181 LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT 224
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 88.7 bits (220), Expect = 4e-27 Identities = 86/86 (100%), Positives = 86/86 (100%) Query: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL 60 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL Sbjct: 1 MDDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCL 60 Query: 61 FLLSGWYGEVLLSYGRQVIFLALAKG 86 FLLSGWYGEVLLSYGRQVIFLALAKG Sbjct: 61 FLLSGWYGEVLLSYGRQVIFLALAKG 86
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 188 bits (478), Expect = 3e-61 Identities = 48/237 (20%), Positives = 104/237 (43%), Gaps = 4/237 (1%) Query: 12 LVASAALGFARVAPIFFFLPFLNSGVLSGAPRNAIIILVALGVWPHALNEAPPFLSVAMI 71 + RV + P L+ + + + +++ + P P S + Sbjct: 12 WLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPANDVPVFSFFAL 71 Query: 72 PLVLQEAAVGVMLGCLLSWPFWVMHALGCIIDNQRGATLSSSIDPANGIDTSEMANFLNM 131 L +Q+ +G+ LG + + F + G II Q G + ++ +DPA+ ++ +A ++M Sbjct: 72 WLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIMDM 131 Query: 132 FAAVVYLQNGGLVTMVDVLNKSYQLCDPMNEC--TPSLPPLLTFINQVAQNALVLASPVV 189 A +++L G + ++ +L ++ E + + L + + N L+LA P++ Sbjct: 132 LALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIFLNGLMLALPLI 191 Query: 190 LVLLLSEVFLGLLSRFAPQMNAFAISLTVKSGIAVLIMLLYFS--PVLPDNVLRLSF 244 +LL + LGLL+R APQ++ F I + + + +M +++ F Sbjct: 192 TLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEIF 248
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 340 bits (875), Expect = e-118 Identities = 120/360 (33%), Positives = 205/360 (56%), Gaps = 19/360 (5%) Query: 1 MSSNKTEKPTKKRLEDSAKKGQSFKSKDLIIACLTLGGIAYLVSYGSFN-EFMGIIKIII 59 MS KTE+PT K++ D+ KKGQ KSK+++ L + A L+ + E + +I Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 60 ADNFDQSMADYSLAVFGIGLKYLIPFMLLCL---VCSALPAL----LQAGFVLATEALKP 112 +QS +S A+ + L+ F LC +AL A+ +Q GF+++ EA+KP Sbjct: 61 ---AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKP 117 Query: 113 NLSALNPVEGAKKLFSMRTVKDTVKTLLYLSSFVVAAIICWKKYKVEIFSQLNGNIVGIA 172 ++ +NP+EGAK++FS++++ + +K++L + V+ +I+ W K + + L GI Sbjct: 118 DIKKINPIEGAKRIFSIKSLVEFLKSILKV---VLLSILIWIIIKGNLVTLLQLPTCGIE 174 Query: 173 VIWRELLLALVLTCLACA---LIVLLLDAIAEYFLTMKDMKMDKEEVKREMKEQEGNPEV 229 I L L + C +++ + D EY+ +K++KM K+E+KRE KE EG+PE+ Sbjct: 175 CITPLLGQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEI 234 Query: 230 KSKRREVHMEILSEQVKSDIENSRLIVANPTHITIGIYFKPELMPIPMISVYETNQRALA 289 KSKRR+ H EI S ++ +++ S ++VANPTHI IGI +K P+P+++ T+ + Sbjct: 235 KSKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQT 294 Query: 290 VRAYAEKVGVPVIVDIKLARSLFKTHRRYDLVSLEEIDEVLRLLVWLE--EVENAGKDVI 347 VR AE+ GVP++ I LAR+L+ + E+I+ +L WLE +E +++ Sbjct: 295 VRKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQHSEML 354
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 128 bits (322), Expect = 2e-40 Identities = 39/160 (24%), Positives = 72/160 (45%), Gaps = 4/160 (2%) Query: 4 QNNVSEERVAEMIWDAVSEGATLKDVHGIPQDMMDGLYAHAYEFYNQGRLDEAETFFRFL 63 Q + + + G T+ ++ I D ++ LY+ A+ Y G+ ++A F+ L Sbjct: 3 QETTDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQAL 62 Query: 64 CIYDFYNPDYTMGLAAVCQLKKQFQKACDLYAVAFTLLKNDYRPVFFTGQCQLLMRKAAK 123 C+ D Y+ + +GL A Q Q+ A Y+ + + R F +C L + A+ Sbjct: 63 CVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAE 122 Query: 124 ARQCF----ELVNERTEDESLRAKALVYLEALKTAETEQH 159 A EL+ ++TE + L + LEA+K + +H Sbjct: 123 AESGLFLAQELIADKTEFKELSTRVSSMLEAIKLKKEMEH 162
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 841 bits (2173), Expect = 0.0 Identities = 592/593 (99%), Positives = 592/593 (99%) Query: 1 MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGE 60 MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGE Sbjct: 1 MVNDASSISRSGYTQNPRLAEAAFEGVRKNTDFLKAADKAFKDVVATKAGDLKAGTKSGE 60 Query: 61 SAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKE 120 SAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKE Sbjct: 61 SAINTVGLKPPTDAAREKLSSEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIESQKE 120 Query: 121 MGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAAAKKLTQAQNKLQSLDPADPG 180 MGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAA KKLTQAQNKLQSLDPADPG Sbjct: 121 MGIQVSKEFQTALGEAQEATDLYEASIKKTDTAKSVYDAATKKLTQAQNKLQSLDPADPG 180 Query: 181 YAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQN 240 YAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQN Sbjct: 181 YAQAEAAVEQAGKEATEAKEALDKATDATVKAGTDAKAKAEKADNILTKFQGTANAASQN 240 Query: 241 QVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEF 300 QVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEF Sbjct: 241 QVSQGEQDNLSNVARLTMLMAMFIEIVGKNTEESLQNDLALFNALQEGRQAEMEKKSAEF 300 Query: 301 QEETRKAEETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAA 360 QEETRKAEETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAA Sbjct: 301 QEETRKAEETNRIMGCIGKVLGALLTIVSVVAAVFTGGASLALAAVGLAVMVADEIVKAA 360 Query: 361 TGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMV 420 TGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMV Sbjct: 361 TGVSFIQQALNPIMEHVLKPLMELIGKAITKALEGLGVDKKTAEMAGSIVGAIVAAIAMV 420 Query: 421 AVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLG 480 AVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLG Sbjct: 421 AVIVVVAVVGKGAAAKLGNALSKMMGETIKKLVPNVLKQLAQNGSKLFTQGMQRITSGLG 480 Query: 481 NVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFML 540 NVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFML Sbjct: 481 NVGSKMGLQTNALSKELVGNTLNKVALGMEVTNTAAQSAGGVAEGVFIKNASEALADFML 540 Query: 541 ARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQNADASRFILRQSRA 593 ARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQNADASRFILRQSRA Sbjct: 541 ARFAMDQIQQWLKQSVEIFGENQKVTAELQKAMSSAVQQNADASRFILRQSRA 593
>BACINVASINC#Salmonella/Shigella invasin protein C signature. Length = 409 Score = 514 bits (1325), Expect = 0.0 Identities = 406/409 (99%), Positives = 408/409 (99%) Query: 1 MLISNVGVNPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSSKVSDLGLSPTLSAPAP 60 MLISNVG+NPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSSKVSDLGLSPTLSAPAP Sbjct: 1 MLISNVGINPAAYLNNHSVENSSQTASQSVSAKDILNSIGISSSKVSDLGLSPTLSAPAP 60 Query: 61 GVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVVQTQLREQQAEVGKFFDIS 120 GVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVVQTQLREQQAEVGKFFDIS Sbjct: 61 GVLTQTPGTITSFLKASIQNTDMNQDLNALANNVTTKANEVVQTQLREQQAEVGKFFDIS 120 Query: 121 GMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAKTTASSMMREGMNALSGSISQ 180 GMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAKTTASSMMREGMNALSGSISQ Sbjct: 121 GMSSSAVALLAAANTLMLTLNQADSKLSGKLSLVSFDAAKTTASSMMREGMNALSGSISQ 180 Query: 181 SALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNSVKLGAEGV 240 SALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNSVKLGAEGV Sbjct: 181 SALQLGITGVGAKLEYKGLQNERGALKHNAAKIDKLTTESHSIKNVLNGQNSVKLGAEGV 240 Query: 241 DSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESLGIKDSNKQISPEHQAILSKRLESV 300 DSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESLGIK+SNKQISPEHQAILSKRLESV Sbjct: 241 DSLKSLNMKKTGTDATKNLNDATLKSNAGTSATESLGIKNSNKQISPEHQAILSKRLESV 300 Query: 301 ESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVTVGGIAGASGQYAATQERSEQQISQVN 360 ESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVTVGGIAGAS QYAATQERSEQQISQVN Sbjct: 301 ESDIRLEQNTMDMTRIDARKMQMTGDLIMKNSVTVGGIAGASRQYAATQERSEQQISQVN 360 Query: 361 NRVASTASDEARESSRKSTSLIQEMLKTMESINQSKASALAAIAGNIRA 409 NRVASTASDEARESSRKSTSLIQEMLKTMESINQSKASALAAIAGNIRA Sbjct: 361 NRVASTASDEARESSRKSTSLIQEMLKTMESINQSKASALAAIAGNIRA 409
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 43.3 bits (102), Expect = 2e-08 Identities = 18/128 (14%), Positives = 46/128 (35%), Gaps = 8/128 (6%) Query: 2 QAHQDIIANIGEKLGL-PLTFDDNNQCLLLLDSDIFTSIEAK--DDIWLLNGMIIPLSPV 58 ++ ++ + L + PL FDD+ C +++D+ ++ + LL G++ P Sbjct: 4 LFYKTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGLLEPH--- 60 Query: 59 CGDSIWRQIMVINGELAANNEGTLAYIEAAETLLFIHAI-TDLTNTYHIISQLESFVNQQ 117 D + ++ N L E + +I + + + ++ + Sbjct: 61 -KDIPQQCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWM 119 Query: 118 EALKNILQ 125 + Q Sbjct: 120 RGWREASQ 127
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 300 bits (770), Expect = 1e-98 Identities = 67/212 (31%), Positives = 101/212 (47%), Gaps = 17/212 (8%) Query: 340 GKPVALAGSYPKNTPDALEAHMKMLLEKECSCLVVLTSEDQMQAKQ--LPAYFRGSYTFG 397 G +A YP LE+H +ML E L VL S ++ ++ +P YFR S T+G Sbjct: 252 GNTRTIACQYP--LQSQLESHFRMLAENRTPVLAVLASSSEIANQRFGMPDYFRQSGTYG 309 Query: 398 EVHTNSQKVSSASQGGAI--DQYNMHL-SCGEKQYTIPVLHVKNWPDHQPLPS--TDQLE 452 + S+ G I D Y + + G+K ++PV+HV NWPD + S T L Sbjct: 310 SITVESKMTQQVGLGDGIMADMYTLTIREAGQKTISVPVVHVGNWPDQTAVSSEVTKALA 369 Query: 453 YLADRVKNSNQNGAPGRSSS-----DKHLPMIHCLGGVGRTGTMAAALVLKDNPHSNL-- 505 L D+ + +N + SS K P+IHC GVGRT + A+ + D+ +S L Sbjct: 370 SLVDQTAETKRNMYESKGSSAVGDDSKLRPVIHCRAGVGRTAQLIGAMCMNDSRNSQLSV 429 Query: 506 EQVRADFRDSRNNRMLEDASQF-VQLKAMQAQ 536 E + + R RN M++ Q V +K + Q Sbjct: 430 EDMVSQMRVQRNGIMVQKDEQLDVLIKLAEGQ 461
>PF07212#Hyaluronoglucosaminidase Length = 336 Score = 28.1 bits (62), Expect = 0.044 Identities = 12/39 (30%), Positives = 21/39 (53%) Query: 234 MSTSTLKRKLAEEGTSFSDIYLSARMNQAAKLLRIGNHN 272 +S +K++ +GT+ IY+++ KLLRI N Sbjct: 241 LSIDIVKKQKGGKGTAAQGIYINSTSGTTGKLLRIRNLG 279
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 42.6 bits (100), Expect = 7e-07 Identities = 33/167 (19%), Positives = 63/167 (37%), Gaps = 10/167 (5%) Query: 23 LLKGLDQEQANEVIAVLQMHNIEANKIDSGKLGYSITVAEPDFTAAVYWIKTYQLPPRPR 82 L L + ++A L NI + +G +I V + LP Sbjct: 53 LFSNLSDQDGGAIVAQLTQMNI-PYRFANG--SGAIEVPADKVHELRLRLAQQGLPKGGA 109 Query: 83 VEIAQMFPADSLVSSPRAEKARLYSAIEQRLEQSLQTMEGVLSARVHISYDIDA---GEN 139 V + + S +E+ A+E L ++++T+ V SARVH++ + E Sbjct: 110 VGFE-LLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQ 168 Query: 140 GRPPKPVHLSALAVYERGSPLAHQISDIKRFLKNSFADVDYDNISVV 186 P V ++ QIS + + ++ A + N+++V Sbjct: 169 KSPSASVTVTLEPGRALDEG---QISAVVHLVSSAVAGLPPGNVTLV 212
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 30.5 bits (68), Expect = 0.007 Identities = 16/57 (28%), Positives = 30/57 (52%), Gaps = 8/57 (14%) Query: 201 IISDLTRKWSQAEVAGKLFMSVSSLKRKLAAEEVSFSKIYLDARMNQAIKLLRMGAG 257 ++ LT + Q + F+S SS +R ++++YL+ RM +A++ R G G Sbjct: 66 VLDHLTGRSCQVGSSNSAFVSTSSSRR--------YTEVYLEHRMQEAVEAERAGRG 114
>adhesinb#Adhesin B signature. Length = 310 Score = 321 bits (824), Expect = e-112 Identities = 89/309 (28%), Positives = 164/309 (53%), Gaps = 14/309 (4%) Query: 4 LHRLKTLLIAGIVAILAL-------SPAYAKEKFKVITTFTVIADMAKNVAGDAAEVSSI 56 + + + L++ + + S K V+ T ++IAD+ KN+AGD + SI Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKNIAGDKINLHSI 60 Query: 57 TKPGAEIHEYQPTPGDIKRAQGAQLILANGLNLER----WFARFYQHLSGVPE---VVVS 109 G + HEY+P P D+K+ A LI NG+NLE WF + ++ VS Sbjct: 61 VPVGQDPHEYEPLPEDVKKTSQADLIFYNGINLETGGNAWFTKLVENAKKKENKDYYAVS 120 Query: 110 TGVKPMGITEGPYNGKPNPHAWMSAENALIYVDNIRDALVKYDPDNAQIYKQNAERYKAK 169 GV + + GK +PHAW++ EN +IY NI L + DP N + Y++N + Y K Sbjct: 121 EGVDVIYLEGQSEKGKEDPHAWLNLENGIIYAQNIAKRLSEKDPANKETYEKNLKAYVEK 180 Query: 170 IRQMADPLRAELEKIPADQRWLVTSEGAFSYLARDNDMKELYLWPINADQQGTPKQVRKV 229 + + + + IP +++ +VTSEG F Y ++ ++ Y+W IN +++GTP Q++ + Sbjct: 181 LSALDKEAKEKFNNIPGEKKMIVTSEGCFKYFSKAYNVPSAYIWEINTEEEGTPDQIKTL 240 Query: 230 IDTIKKHHIPAIFSESTVSDKPARQVARESGAHYGGVLYVDSLSAADGPVPTYLDLLRVT 289 ++ ++K +P++F ES+V D+P + V++++ ++ DS++ +Y +++ Sbjct: 241 VEKLRKTKVPSLFVESSVDDRPMKTVSKDTNIPIYAKIFTDSVAEKGEEGDSYYSMMKYN 300 Query: 290 TETIVNGIN 298 E I G++ Sbjct: 301 LEKIAEGLS 309
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 382 bits (982), Expect = e-128 Identities = 143/373 (38%), Positives = 206/373 (55%), Gaps = 39/373 (10%) Query: 350 YQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYNVLKQVEMVAQSDSTVLILG 409 E+ + R + E +L + + ++GRS AM + + + + Q+D T++I G Sbjct: 108 LTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 410 ETGTGKELIARAIHNLSGRSGRRMVKMNCAAMPAGLLESDLFGHERGAFTGASAQRIGRF 469 E+GTGKEL+ARA+H+ R V +N AA+P L+ES+LFGHE+GAFTGA + GRF Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRF 227 Query: 470 ELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSNKLIQTDVRLIAATNRDLKKMV 529 E A+ +LFLDE+GDMP++ Q +LLRVLQ+ E+ +G I++DVR++AATN+DLK+ + Sbjct: 228 EQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSI 287 Query: 530 ADREFRNDLYYRLNVFPIQLPPLRERPEDIPLLVKAFTFKIARRMGRNIDSIPAETLRTL 589 FR DLYYRLNV P++LPPLR+R EDIP LV+ F + A + G ++ E L + Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV-QQAEKEGLDVKRFDQEALELM 346 Query: 590 SGMEWPGNVRELENVVERAVLLTRGNVLQLS-LPDITAVTPDTSPVATESAKEG------ 642 WPGNVRELEN+V R L +V+ + + SP+ +A+ G Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQ 406 Query: 643 ----------------------------EDEYQLIIRVLKETNGVVAGPKGAAQRLGLKR 674 E EY LI+ L T G AA LGL R Sbjct: 407 AVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIK---AADLLGLNR 463 Query: 675 TTLLSRMKRLGID 687 TL +++ LG+ Sbjct: 464 NTLRKKIRELGVS 476
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 27.0 bits (59), Expect = 0.011 Identities = 19/75 (25%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Query: 12 IDGNQAKVD--VCGIQRDVDLTLVGSCDENGQPRLGQWVLVHVGFAMSVINEAEARDTLD 69 I GNQ + D G+ D L ++NG+P G W+ + + F + ++ ++ D + Sbjct: 171 IIGNQIRTDQKFMGV-FDESLKERQEAEKNGEPTGGDWLDIFLSF---IFDKKQSSDVKE 226 Query: 70 ALQN--MFDVEPDVG 82 A+ + V+PD+ Sbjct: 227 AINQEPVPHVQPDIA 241
>INTIMIN#Intimin signature. Length = 939 Score = 27.3 bits (60), Expect = 0.030 Identities = 20/69 (28%), Positives = 33/69 (47%), Gaps = 6/69 (8%) Query: 82 SVDDQVKTTTPAAESQFYTVKSGDTLSAISKQVYGNANLYNKIFEANKPMLKSPE---KI 138 D ++ T FYT+K+G+T++ +SK N + I+ NK + S K Sbjct: 48 GSDSKLLTHNSYQNRLFYTLKTGETVADLSKSQDINLST---IWSLNKHLYSSESEMMKA 104 Query: 139 YPGQVLRIP 147 PGQ + +P Sbjct: 105 EPGQQIILP 113
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.8 bits (241), Expect = 2e-25 Identities = 35/122 (28%), Positives = 61/122 (50%), Gaps = 1/122 (0%) Query: 2 RLLLAEDNRELAHWLEKALVQNGFAVDCVFDGLAADHLLHSEMYALAVLDINMPGMDGLE 61 +L+A+D+ + L +AL + G+ V + + + L V D+ MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VVQRLRKRGQTLPVLLLTARSAVADRVKGLNVGADDYLPKPFELEE-LDARLRALLRRSA 120 ++ R++K LPVL+++A++ +K GA DYLPKPF+L E + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GQ 122 Sbjct: 125 RP 126
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.006 Identities = 23/101 (22%), Positives = 39/101 (38%), Gaps = 21/101 (20%) Query: 370 LLDNALKY----TPEQGIVTARLERDSDAVTLVVEDSGPGIDDEHIHLALQPFHRLDNVG 425 L++N +K+ P+ G + + +D+ VTL VE++G L N Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA--------------LKNTK 308 Query: 426 NVAGAGIGLALVND-IARLHRTHPHFSRSEALGGLYVRIRF 465 G GL V + + L+ T SE G + + Sbjct: 309 E--STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.032 Identities = 44/217 (20%), Positives = 64/217 (29%), Gaps = 49/217 (22%) Query: 992 PPG----TVVAVVGRSGVGKSTLIKLLAGLYSPGSGQIRVGER-----------LIDAAS 1036 PG V + G G+GKSTLI L GL +G + + Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSE 649 Query: 1037 LSDYRRQTGLVTQDVALFSGDIAENI-RYSRPDSSDTEVEIAARRAGLFETV---QHL-- 1090 ++ +RR D + RY V+ R+ ++ T Q+L Sbjct: 650 MTAFRR------ADAEAVKAFFSSRKDRYRGA--YGRYVQDHPRQVVIWCTTNKRQYLFD 701 Query: 1091 PLGFRT--PVNNGG----TDLSAGQRQLIALARAQLAQ----------AHILLLDEATAR 1134 G R PV G L + QL A A I E R Sbjct: 702 ITGNRRFWPVLVPGRANLVWLQKFRGQLFAEALHLYLAGERYFPSPEDEEIYFRPEQELR 761 Query: 1135 -IDRSAEERLITSLTGVTHTEKRIALIVAHRLTTARR 1170 ++ + RL LT A A + + Sbjct: 762 LVETGVQGRLWALLTREG---APAAEGAAQKGYSVNT 795
>FLAGELLIN#Flagellin signature. Length = 507 Score = 280 bits (718), Expect = 8e-91 Identities = 267/510 (52%), Positives = 316/510 (61%), Gaps = 13/510 (2%) Query: 2 AQVINTNSLSLLTQNNLNKSQSALGTAIERLSSGLRINSAKDDAAGQAIANRFTANIKGL 61 AQVINTNSLSLLTQNNLNKSQS+L +AIERLSSGLRINSAKDDAAGQAIANRFT+NIKGL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 TQASRNANDGISIAQTTEGALNEINNNLQRVRELAVQSANSTNSQSDLDSIQAEITQRLN 121 TQASRNANDGISIAQTTEGALNEINNNLQRVREL+VQ+ N TNS SDL SIQ EI QRL Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 EIDRVSGQTQFNGVKVLAQDNTLTIQVGANDGETIDIDLKQINSQTLGLDSLNVQKAYDV 181 EIDRVS QTQFNGVKVL+QDN + IQVGANDGETI IDL++I+ ++LGLD NV + Sbjct: 121 EIDRVSNQTQFNGVKVLSQDNQMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKEA 180 Query: 182 SATDVISSTYSDGTQALTAPTATDIKAALGNPTVTGDTLTAAVSFKDGKYYATVSGYTDA 241 + D+ SS + A A + + + V DT V D Y +G Sbjct: 181 TVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVP--DKVYVNAANGQLTT 238 Query: 242 GDTAKNGKYEVTVDSATGAVSFGATPTKSTVTGDTAVTKVQVNAPVAADAATKKALQDGG 301 D N ++ + + A + A + G V TK G Sbjct: 239 DDAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKG-VTFTIDTKTGNDGNG 297 Query: 302 VSSADANAATLVKMSYTDKNGKTIEGGYALKAGDKYYAA------DYDEATGAIKAKTTS 355 S N + G L++ Y + +D+ T AK + Sbjct: 298 KVSTTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSD 357 Query: 356 YTAADGTTKTAANQLGGVDG----KTEVVTIDGKTYNASKAAGHDFKAQPELAEAAAKTT 411 A + + + G + + VT+ GKT K A E A AA K+T Sbjct: 358 LEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKST 417 Query: 412 ENPLQKIDAALAQVDALRSDLGAVQNRFNSAITNLGNTVNNLSEARSRIEDSDYATEVSN 471 NPL ID+AL++VDA+RS LGA+QNRF+SAITNLGNTV NL+ ARSRIED+DYATEVSN Sbjct: 418 ANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSN 477 Query: 472 MSRAQILQQAGTSVLAQANQVPQNVLSLLR 501 MS+AQILQQAGTSVLAQANQVPQNVLSLLR Sbjct: 478 MSKAQILQQAGTSVLAQANQVPQNVLSLLR 507
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 243 bits (621), Expect = 3e-78 Identities = 95/432 (21%), Positives = 176/432 (40%), Gaps = 56/432 (12%) Query: 18 ERAFSGAGRIVLICSLLFLILGI-WAWFGRLDEVSTGNGKVIPSSREQVLQSLDGGILAQ 76 E S R+V + FL++ + G+++ V+T NGK+ S R + ++ ++ I+ + Sbjct: 50 ETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKE 109 Query: 77 LTVREGDRVQANQIVARLDPTRLASNVGESAAKYRASLASSARLTAEVSDLPL------- 129 + V+EG+ V+ ++ +L ++ ++ + + R + L Sbjct: 110 IIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELK 169 Query: 130 --AFPAELNGWPDLIAAETRLYKSR-----------RAQLADTEAELRDALASVNK---- 172 P N + + T L K + L AE LA +N+ Sbjct: 170 LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENL 229 Query: 173 ------ELAITQRLEKSGAASHVEVLRLQRQKSDLG---------------------LKI 205 L L A + VL + + + + Sbjct: 230 SRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEY 289 Query: 206 TDLRSQYYVQAREALSKANAEVDMLSAILKGREDSVTRLTVRSPVRGIVKNIQVTTIGGV 265 + + + + L + + +L+ L E+ +R+PV V+ ++V T GGV Sbjct: 290 QLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 266 IPPNGEMMEIVPVDDRLLIETRLSPRDIAFIHPGQRALVKITAYDYAIYGGLDGVVETIS 325 + +M IVP DD L + + +DI FI+ GQ A++K+ A+ Y YG L G V+ I+ Sbjct: 350 VTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409 Query: 326 PDTIQDKVKPEIFYYRVFIRTHQDYLQNKSGRRFSIVPGMIATVDIKTGEKTIVDYLIKP 385 D I+D+ + V I ++ L + + GM T +IKTG ++++ YL+ P Sbjct: 410 LDAIEDQRLGL--VFNVIISIEENCLSTG-NKNIPLSSGMAVTAEIKTGMRSVISYLLSP 466 Query: 386 F-NRAKEALRER 396 E+LRER Sbjct: 467 LEESVTESLRER 478
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 5e-04 Identities = 32/224 (14%), Positives = 63/224 (28%), Gaps = 32/224 (14%) Query: 209 DVVQTEARIESARSQLAQYQANLDSAKASLMSWLGWNSLNGINNDFPAKLARSCETATPD 268 + EA +S L Q + + S D P S E Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187 Query: 269 DRLVPAVLAAW-AQANVARANLDYASAQ---MTPTISLEPSVQHYLNDKYPSHEVLDKTQ 324 L+ + W Q NLD A+ + I+ ++ + L Q Sbjct: 188 TSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ 247 Query: 325 YSTWVKVEMPLYQGGGLTARRNAASHAVDAAQSTIQRTRLDVRQKLMEARSQAMSLASAL 384 V + ++ +L +SQ + S Sbjct: 248 AIAKHAVL-------------------------EQENKYVEAVNELRVYKSQLEQIES-- 280 Query: 385 QILRRQQQLSERTRELYQQQYLDLGSRPLLDVLNAEQEVYQARF 428 +IL +++ T +L++ + LD + ++ E+ + Sbjct: 281 EILSAKEEYQLVT-QLFKNEILDKLRQTTDNIGLLTLELAKNEE 323
>INTIMIN#Intimin signature. Length = 939 Score = 43.1 bits (101), Expect = 3e-05 Identities = 66/311 (21%), Positives = 102/311 (32%), Gaps = 30/311 (9%) Query: 2724 TPAQTNGQPLLAFAQDKAGNTGIAAGFTAPDTRVPEAPIITNVVDDVGIYTGAIANGQ-- 2781 +N + A A D+ GN+ T + V D T A A+G Sbjct: 518 VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 2782 VTNDAQPTLNGTAQAGATVS--IYNNGALLGTTTANASGNWSFTPTGNLTEGSHAFT-AT 2838 +T A NG AQA VS I + A+L +AN +G+ T T L + Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVT--LKSDKPGQVVVS 635 Query: 2839 ATNANGTGSVSTAATVIVDTLAPGTPSGTLSADGGSLSGQAEANSTVTVTLAGG------ 2892 A A T +++ A + VD +GQ TV V Sbjct: 636 AKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 2893 VTLTTTAG----------SNGAWSLTLPTKQIEGQLINVTATDAAGN-ASGALGITAPVL 2941 VT TTT G +NG +TL + L++ +D A + + + + Sbjct: 696 VTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLT 755 Query: 2942 PLAARDNITSLDLTSTAVTSTQNYSDYGLLLVGALGNVASVLGN------DTAQVEFIIA 2995 I + T Y L G G N D + + + Sbjct: 756 IDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVTLK 815 Query: 2996 EGGTGDVTIDA 3006 E GT +++ + Sbjct: 816 EKGTTTISVIS 826 Score = 39.3 bits (91), Expect = 4e-04 Identities = 79/414 (19%), Positives = 146/414 (35%), Gaps = 39/414 (9%) Query: 2197 IYNGSALVGTA-QVQANGSWSFT-------PSTSLGAGVWNLTATATDAAGNTSAASEIR 2248 +++ SAL Q+Q +GS S G+ V+ +TA A D GN+S + + Sbjct: 486 VWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQGGSNVYKVTARAYDRNGNSS-NNVLL 544 Query: 2249 SFTIDTTAPAAPVIDTVYDGTGPITGNLSSGQ--ITDEARPVISGTREAN--TTIRLYDN 2304 + T+ + V D T T + G IT A +G +AN + + Sbjct: 545 TITV-LSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSG 603 Query: 2305 GTLLAEIPADNSNSWRYTPDASLATGNHVITVIAVDAAGNASPV-SDSVNFVVDTTPPLT 2363 +L+ A+ + S + T +L + V++ A S + +++V FV T +T Sbjct: 604 TAVLSANSANTNGSGKAT--VTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASIT 661 Query: 2364 PVITSVSDDQAPGLGTIANGQN--TNDPTPTFSGTAEAGATITLYENGTVIGTTTAQ--P 2419 + A +ANGQ+ T + +T + +T + Sbjct: 662 EI--KADKTTA-----VANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDT 714 Query: 2420 DGAWSVSTSKLTSGTHVITAVATDAAGNSSPNSTAFTLTVDTTAPQTPILTSVVDDVAGG 2479 +G V+ + T G +++A +D A + F T+ I+ + V Sbjct: 715 NGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPT 774 Query: 2480 VTGNLANGQITNDNRPTLNGTAEAGSVISIYDGNTLLGVTSANAGGAWSFTPTTGLNDGT 2539 V + A I+ D ++ G + G + + + N Sbjct: 775 VWLQYGQVNLKASGGNGKYTWRSANPAIASVDASS--GQVTLKEKGTTTISVISSDN--- 829 Query: 2540 RTLTVTATDPAGNVSPATSGFTIVVD------TLAPTVPLITSIVDDVPNNTGA 2587 +T T T P + P S D +P + +++V GA Sbjct: 830 QTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGA 883 Score = 36.6 bits (84), Expect = 0.003 Identities = 63/279 (22%), Positives = 90/279 (32%), Gaps = 36/279 (12%) Query: 1508 TLPVTSALPDGVYTLTAIAADAAGNSSGVSNSFTFTVDTVPLLPPVVN--EILDDVAPVT 1565 LP VY +TA A D GNS SN+ T+ TV VV+ + D A T Sbjct: 513 ILPAYVQGGSNVYKVTARAYDRNGNS---SNNVLLTI-TVLSNGQVVDQVGVTDFTADKT 568 Query: 1566 GPLTDG--AFTNDRTLTINGSGENGSTVTIYDNGVAIGTALVTDGVWTFN-----TPELS 1618 DG A T T+ NG + V+ + GTA+++ N T L Sbjct: 569 SAKADGTEAITYTATVKKNGVAQANVPVSF---NIVSGTAVLSANSANTNGSGKATVTLK 625 Query: 1619 EVSHALTFSATDDAGNTTAQTQPITITVDITAPPAPTIQTVDDDGTRVAGRADPYA-TVE 1677 + A T+A I VD T I+ T VA D TV+ Sbjct: 626 SDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKT--TAVANGQDAITYTVK 683 Query: 1678 IHHADGTLVGSAVANGTGEFVVTLSPAQTDG---------GTLTAIAIDRAGNNGPATNF 1728 + D + V T ++ S +TD T ++ A + A + Sbjct: 684 VMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDV 743 Query: 1729 PASDSGLPAVPAITAIEDNVGSVQGNIAAGGATDDTTPT 1767 A + I + G PT Sbjct: 744 KAPEVEFFTTLTIDDGNIEI--------VGTGVKGKLPT 774
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 33/177 (18%), Positives = 69/177 (38%), Gaps = 3/177 (1%) Query: 213 FWLLFMILALGVFSGMVISSSSAQIGMTQYGLLSGAL-VVSLVSIFNSIGRLFWGGLTDK 271 WL + V + MV++ S I + V + + SIG +G L+D+ Sbjct: 17 IWLCILSF-FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 272 LGGYNTLVIVYLFTCVCMLLLLFFNGNTSVFYFSALGVGFAYAGILVIFPGLTSQNFGMR 331 LG L+ + C ++ + S+ + G A + + ++ Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 332 NQGLNYGFMYFGFAVGAVIAPYVTSAIAKYTGSYNTVFILTTVLLLIGVVLTLITKK 388 N+G +G + A+G + P + IA Y ++ + ++ + ++ L + KK Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH-WSYLLLIPMITIITVPFLMKLLKK 191
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 119 bits (299), Expect = 1e-31 Identities = 84/368 (22%), Positives = 148/368 (40%), Gaps = 68/368 (18%) Query: 23 GIDLGTTNSLVATVRSGQAETLPDHEGRHLLPSVVHYQQQGHTVGYAARDNAAQDTANTI 82 IDLGT N+L+ G + +E PSVV A + ++ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVV------------AIRQDRAGSPKSV 52 Query: 83 SSV----KRMMGRSLADIQARYPHLPYRFKASVNGLPMIDTAAGLLNPVRVSADILKALA 138 ++V K+M+GR+ +I A P M D G++ V+ +L+ Sbjct: 53 AAVGHDAKQMLGRTPGNIAAIRP--------------MKD---GVIADFFVTEKMLQHFI 95 Query: 139 ARA-SESLSGELDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDS 197 + S S V++ VP +R+ +++A+ AG + L+ EP AAAI GL Sbjct: 96 KQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPV 155 Query: 198 GKEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG--I 255 + V D+GGGT +++++ L+ V +GGD FD + +Y+R G I Sbjct: 156 SEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSLI 210 Query: 256 ADRSDNRVQRELLDAAIAAKIALSDADTVRVNVAG---WQG-----EITREQFNDLISAL 307 + + R++ E+ A + + V G +G + + + + Sbjct: 211 GEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEP 263 Query: 308 VKRTLLACRRALKDAGVD-PQDVLE--VVMVGGSTRVPLVRERVGEFFGRTPLTAIDPDK 364 + + A AL+ + D+ E +V+ GG + + + E G + A DP Sbjct: 264 LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLT 323 Query: 365 VVAIGAAI 372 VA G Sbjct: 324 CVARGGGK 331
>INTIMIN#Intimin signature. Length = 939 Score = 342 bits (879), Expect = e-107 Identities = 176/578 (30%), Positives = 269/578 (46%), Gaps = 41/578 (7%) Query: 53 KGKTFKEQGANYFINSATQGFDNLTPEALES-QARGYIQGQVTSSAQSYLEGMLSPYGKV 111 K ++ NY A L +L A+ G + A S L+ L YG Sbjct: 154 KSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTA 213 Query: 112 RTSLSIGEGGDLDGSSLDYFIPWYDNQSTLFFSQISAQRKEDRTIGNVGLGVRQNVGNWL 171 +L G + DGSSLD+ +P+YD++ L F Q+ A+ + R N+G G R + + Sbjct: 214 EVNLQSGN--NFDGSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENM 271 Query: 172 LGGNAFYDYDFTRGHRRLGLGTEAWTDYLKFSGNYYHPLSDWKDSKDFDFYEERPARGWD 231 LG N F D DF+ + RLG+G E W DY K S N Y +S W +S + Y+ERPA G+D Sbjct: 272 LGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFD 331 Query: 232 IRMESWLPFYPQLGAKLVYEQYYGDEVALFGTDNLQKDPHAVTVGLNYTPVPLVTVGTDY 291 IR +LP YP LGAKL+YEQYYGD VALF +D LQ +P A TVG+NYTP+PLVT+G DY Sbjct: 332 IRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDY 391 Query: 292 KAGTGDSNDFSVNATVNYQIGTPLAAQLDPENVKIQHSLMGSRTDFVDRNNFIVLEYREK 351 + GTG+ ND + YQ P + Q++P+ V +L GSR D V RNN I+LEY+++ Sbjct: 392 RHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQ 451 Query: 352 DPLDVTLWLKADATNEHPECVIEDTPEAAVGLEKCKWTVNALINHHYKIISASWQAKNNA 411 D L + + + T E I+ ++ GL++ W +AL + +I + Q+ + Sbjct: 452 DILSLNIPHDINGT-ERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQD- 509 Query: 412 ARTLVMPVVKADALTEGNNNRWNLVLPAWVNADTEEQRTALNTWKVRMTLEDEKGNKQNS 471 + +LPA+V + N +KV D GN N+ Sbjct: 510 ---------------------YQAILPAYV-------QGGSNVYKVTARAYDRNGNSSNN 541 Query: 472 GVVEITVQQDRKIELIVDNIADTDRSDHSHEASALADGEDGVVMDLLITDSFGD-ATDRN 530 ++ ITV + +VD + TD + + + SA ADG + + + + A Sbjct: 542 VLLTITVLSN---GQVVDQVGVTDFT--ADKTSAKADGTEAITYTATVKKNGVAQANVPV 596 Query: 531 GNELVDDAMTPVLYDSNDKKVTLAQTPCTTETPCVFIASRDKEAGTVTLSSTLPGTFRWK 590 +V +N A ++ P + S T L++ Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNA--NAVIFVD 654 Query: 591 AKADAYGDSNYVDVTFIGDNLSALNAVIYQVKAANPVN 628 + + T + + A+ + +K PV+ Sbjct: 655 QTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVS 692
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 89.0 bits (220), Expect = 1e-19 Identities = 124/532 (23%), Positives = 196/532 (36%), Gaps = 47/532 (8%) Query: 1318 VNVASGATFGGSNGTTVNGKVTNEGTLVFGDSEETGAIFTLNGDLINMGTMTSGSSASTP 1377 V +AS A + G+ V+ + T V D+ GA+ L + G++ A Sbjct: 415 VALASQARWTGAT-RAVDSLSIDNATWVMTDNSNVGAL-----RLASDGSVDFQQPAEAG 468 Query: 1378 GNTLYVDGDYTGNGGSLYLNTVLGDDDSATDKLVITGDASGTTDLYINGIGNGAQTTNGI 1437 + G+G +N D +DKLV+ DASG L++ G+ + N + Sbjct: 469 RFKVLTVNTLAGSG-LFRMNVFA--DLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTL 525 Query: 1438 EVVDVGGTSTSDAFVLKN---EVNASLYTYRLYWNESDNDWYLASKAQSDDDDSGSDVTP 1494 +V S + F L N +V+ Y YRL N + + +KA + Sbjct: 526 LLVQTPLGSAA-TFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQ---- 580 Query: 1495 PDDDSDVTPSDDGDDGGNVTPPDDGGDVAPQYRADIGAYMGNQ--WMARNLQMQTLYDRE 1552 P P + P A + G W A + L R Sbjct: 581 PGPQPPQPPQPQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLWYA---ESNALSKRL 637 Query: 1553 GSQYRNAD-GSVWARFKAGKAESEAVSGNIDMDSNYSQFQLGGDILAWGNGQQSVTVGVM 1611 G N D G W R A + + + +G D + F+LG D A +G + Sbjct: 638 GELRLNPDAGGAWGRGFAQRQQLDNRAGR-RFDQKVAGFELGAD-HAVAVAGGRWHLGGL 695 Query: 1612 ASYINADTDSTGNRGADGSQFTSSSNVDGYNLGVYATWFADAQTHSGAYVDSWYQYGFYN 1671 A Y D TG+ G D ++G YAT+ AD SG Y+D+ + Sbjct: 696 AGYTRGDRGFTGDGGGH---------TDSVHVGGYATYIAD----SGFYLDATLRASRLE 742 Query: 1672 N--SVESGDAGSESYDSTANAV--SLETGYRYDIALSNGNTVSLTPQAQVVWQNYSADSV 1727 N V D + + V SLE G R+ A + L PQA++ + Sbjct: 743 NDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHA----DGWFLEPQAELAVFRAGGGAY 798 Query: 1728 KDNYGTRIDGQDSDSWTTRLGLRVDGKLYKGSRTVIQPFAEANWLHTSD-DVSVSFDDAT 1786 + G R+ + S RLGL V ++ +QP+ +A+ L D +V + Sbjct: 799 RAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQVQPYIKASVLQEFDGAGTVHTNGIA 858 Query: 1787 VKQDLPANRAELKVGLQADIDKQWSVRAQVAGQTGSNDFGDLNGSLNLRYNW 1838 + +L RAEL +G+ A + + S+ A G RY+W Sbjct: 859 HRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGPKLAMPWTFHAGYRYSW 910
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 37.6 bits (87), Expect = 4e-05 Identities = 31/149 (20%), Positives = 53/149 (35%), Gaps = 28/149 (18%) Query: 290 NQLTSDLLDQWSKGNVRQQHAAQYGRALQAMEASKYDEARKTLQPLLSAEPNNAWYLDLA 349 N+++SD L+Q Y A ++ KY++A K Q L + ++ + Sbjct: 29 NEISSDTLEQL------------YSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGL 76 Query: 350 TDIDLGQKRANDAINRLKNARDLRVN-PVLQLNLANAYLQGGQPKAAETILNRYTFSHKD 408 + + AI+ + + P + A LQ G+ AE+ L Sbjct: 77 GACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLF-------- 128 Query: 409 DGNGWDLLAQAEAALNNRDQELAARAESY 437 LAQ A +EL+ R S Sbjct: 129 -------LAQELIADKTEFKELSTRVSSM 150
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.005 Identities = 9/70 (12%), Positives = 25/70 (35%), Gaps = 6/70 (8%) Query: 283 DHALPALLSGLSESWQVQELSRLWLQLAQHDAKGVLQQTLRTWFEHNCDLTQTAKALHIH 342 + + + ++ L L ++ ++ L + + A L ++ Sbjct: 409 EENMRQYFASFGDALPPSGLYDRVLAEMEYP---LILAALT---ATRGNQIKAADLLGLN 462 Query: 343 VNTLRYRLQR 352 NTLR +++ Sbjct: 463 RNTLRKKIRE 472
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 31.4 bits (71), Expect = 0.007 Identities = 25/122 (20%), Positives = 50/122 (40%), Gaps = 13/122 (10%) Query: 459 SRIAVHPARQREGIGQQLIACACMQVAQCDYLSVSFGYT-------PELWRFWQRCGFVL 511 SR V +R ++ +G + + + ++ +Y S GY + +R G+ Sbjct: 100 SRFFVDKSRAKDILGNEYPISSMLFLSMINY-SKDKGYDGIYTIVSHPMLTILKRSGWG- 157 Query: 512 VRMGNHREASSGCYTAMALLPLSDAGQ-RLAQQEHRRLRRDADILTQWNGEAIPLAALRE 570 +R+ + + LP+ D Q LA++ +R ++ L QW + + A Sbjct: 158 IRVVEQGLSEKEERVYLVFLPVDDENQEALARRINRSGTFMSNELKQW---PLRVPAAIA 214 Query: 571 QA 572 QA Sbjct: 215 QA 216
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 49.4 bits (118), Expect = 5e-09 Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 9/116 (7%) Query: 64 VRDGIVWDFFGAVTLVRRHIDTLEQQLGCRFT-HAATSFPPGTDP---RISINVLESAGL 119 ++DG++ DFF +++ I + R + P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 120 EVSHVLDEPTAVA---DLLALDNAG--VVDIGGGTTGIAIVKQGKVTYSADEATGG 170 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.3 bits (78), Expect = 9e-04 Identities = 12/33 (36%), Positives = 16/33 (48%) Query: 30 MVALLGPSGSGKTTLLRIIAGLEHQSSGHIRFH 62 V L G G GK+TL+ + GL+ S H Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIG 630
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.0 bits (104), Expect = 7e-07 Identities = 80/362 (22%), Positives = 135/362 (37%), Gaps = 30/362 (8%) Query: 14 NFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHELGYSNTMV---GIAVGIQFFATVLTRGY 70 N L I V L + +GL +PV+P + +L +SN + GI + + Sbjct: 4 NRPLIVILSTVALDAVGIGLIMPVLPGLLR-DLVHSNDVTAHYGILLALYALMQFACAPV 62 Query: 71 AGRLADQYGAKRSALQGMFACGLAGAAWLLAALLPVSAPVKFALLIVGRLILGFGESQLL 130 G L+D++G + + LAGAA + + +AP +L +GR++ G + Sbjct: 63 LGALSDRFGRRP-----VLLVSLAGAA--VDYAIMATAPF-LWVLYIGRIVAGITGATGA 114 Query: 131 TGTLTWGLGLVGPTRSGKVMSWNGMAIYGALAAGAPLGLL---IHSHFGFAALAGTTMVL 187 G R+ + + + AG LG L H F A A + Sbjct: 115 VAGAYIADITDGDERA-RHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLN 173 Query: 188 PLLAWAFNGTVRKVPAYTGERPSLWSVVGLIWKPGL-----------GLALQGVGFAVIG 236 L K R +L + W G+ + L G A + Sbjct: 174 FLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALW 233 Query: 237 TFISLYFVSNGWTMAGFTLTAFGGAFVLMR-MLFGWMPDRFGGVKVAVVSLLVETAGLLL 295 T G +L AFG L + M+ G + R G + ++ ++ + G +L Sbjct: 234 VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYIL 293 Query: 296 LWLAPTAWIALVGAALTGAGCSLIFPALGVEVVKRVPAQVRGTALGGYAAFQDISYGVTG 355 L A W+A L +G + PAL + ++V + +G G AA ++ + G Sbjct: 294 LAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLT-SIVG 351 Query: 356 PL 357 PL Sbjct: 352 PL 353 Score = 29.4 bits (66), Expect = 0.027 Identities = 32/137 (23%), Positives = 46/137 (33%), Gaps = 12/137 (8%) Query: 261 AFVLMRMLF----GWMPDRFGGVKVAVVSLLVETAGLLLLWLAPTAWIALVG---AALTG 313 + LM+ G + DRFG V +VSL ++ AP W+ +G A +TG Sbjct: 51 LYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITG 110 Query: 314 AGCSLIFPALGVEVVKRVPAQVRGTALGGYAAFQDISYGVTGPLAGMLATSCGYPSVFLA 373 A G + R G +A V GP+ G L + F A Sbjct: 111 A----TGAVAGAYIADITDGDERARHFGFMSACFGFGM-VAGPVLGGLMGGFSPHAPFFA 165 Query: 374 GAISAVVGILVTILSFR 390 A + L Sbjct: 166 AAALNGLNFLTGCFLLP 182
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 28.3 bits (63), Expect = 0.019 Identities = 18/56 (32%), Positives = 25/56 (44%), Gaps = 3/56 (5%) Query: 68 MVTSFT---AVHDVARFGAEVLRASPRQADLMVVAGTCFTKMAPVIQRLYDQMLEP 120 M+TSFT V + R A P Q L + F M+PVI ++Y +P Sbjct: 60 MMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQP 115
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 1e-08 Identities = 33/148 (22%), Positives = 59/148 (39%), Gaps = 16/148 (10%) Query: 185 PGAVAIVAEDSKVARAMLEKGLNAMGIPHQMHVTGKDAWERIQQLAQEAEAEGKPISEKI 244 GA +VA+D R +L + L+ G ++ W I + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIA-------------AGDG 48 Query: 245 ALVLTDLEMPEMDGFTLTRKIKTDERLKKIPVVIHSSLSGSANEDHVRKVKADGYVAK-F 303 LV+TD+ MP+ + F L +IK + +PV++ S+ + + A Y+ K F Sbjct: 49 DLVVTDVVMPDENAFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106 Query: 304 EINELSSVIQEVMERAAQNVSGPLVSRQ 331 ++ EL +I + + S Q Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLEDDSQ 134
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 30.2 bits (68), Expect = 0.002 Identities = 11/74 (14%), Positives = 27/74 (36%), Gaps = 12/74 (16%) Query: 1 MIDWQDLHHSELTVPQLYALLKLRCAVFV--------VEQRCPYLDVDGDDLVGDNRHIL 52 M++ D++H+ L+ + L LR F + D + + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56 Query: 53 GWHQDELVAYARIL 66 G + ++ R + Sbjct: 57 GIKDNTVICSLRFI 70
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.8 bits (62), Expect = 0.031 Identities = 16/75 (21%), Positives = 29/75 (38%), Gaps = 15/75 (20%) Query: 133 AERDTQAYLKLDHDFHYVFVKYADNKYISQAHLLISARLLAIRYRLDFTAEYITSSNRGH 192 A+R+ L F VF+ + A+RY L+ Y S+ G Sbjct: 62 ADREGMTDLFASGHFERVFISPH------RL---------AVRYSLENPHAYADSNLTGF 106 Query: 193 ATILDMLKNNNVEGV 207 IL+ ++N ++ + Sbjct: 107 LNILEGCRHNKIQHL 121
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 30.6 bits (69), Expect = 0.012 Identities = 36/179 (20%), Positives = 68/179 (37%), Gaps = 12/179 (6%) Query: 25 ILYFFNYMDRVNIGFAALRMNESLGITPEDFANISSIFFISYLIFQIPSSIGLQKLGARK 84 IL FF+ ++ + + + + P +++ F +++ I +LG ++ Sbjct: 21 ILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 85 W--ISSIIIGWGAVTGLIFFAKDTQHIL-LARIFLGVFEAGFFPGMVYYLACWFPARERG 141 II +G+V G F +L +AR G A F ++ +A + P RG Sbjct: 81 LLLFGIIINCFGSVIG--FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRG 138 Query: 142 KVNSFFMLSIAVASVLAAPMSGWIIEHLNTPDYEGWRWLFAIEGIPTVFLGILTFYLLP 200 K +A+ + + G I ++ W +L I I T+ LL Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI-TIITVPFLMKLLK 190
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 1e-17 Identities = 29/104 (27%), Positives = 47/104 (45%) Query: 827 ILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNAIDIVLSDVNMPNMDGYRL 886 ILV DD R +L L GY + ++ ++ D+V++DV MP+ + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 887 TQRIRQLGLTLPVVGVTANALAEEKQRCLESGMDSCLSKPVTLD 930 RI++ LPV+ ++A + E G L KP L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 8e-09 Identities = 26/145 (17%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 1 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP 60 M +++ADD + + ++L + + + ++ L + D +++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGA------PT 114 + L+ IK+ P L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 115 DLPKALAALQKGKKFTPESVSRLLE 139 DL + + + + S+L + Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLED 131
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 534 bits (1378), Expect = 0.0 Identities = 260/389 (66%), Positives = 297/389 (76%), Gaps = 17/389 (4%) Query: 1 MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLFGKVDGLHYFSDDKGSDGDQTYMRIG 60 MK KVL+L++PALL AGAA+AAEIYNKDGNKLDL+GKVDGLHYFSDD DGDQTYMR+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQVNDQLTGYGQWEYQIQGNQTEG-SNDSWTRVAFAGLKFADAGSFDYGRNYGVTY 119 FKGETQ+NDQLTGYGQWEY +Q N TEG +SWTR+AFAGLKF D GSFDYGRNYGV Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVTSWTDVLPEFGGDTYG-ADNFMQQRGNGYATYRNTDFFGLVDGLDFALQYQGKNGSVS 178 DV WTD+LPEFGGD+Y ADN+M R NG ATYRNTDFFGLVDGL+FALQYQGKN S S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 GENDG--------GRSLLNQNGDGYGGSLTYAIGEGFSVGGAITTSKRTADQNNTADARL 230 ++ G + NGDG+G S TY IG GFS G A TTS RT +Q N Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNA--GGT 238 Query: 231 YGNGDRATVYTGGLKYDANNIYLAAQYSQTYNATRFGTSNGNNKSDSYGFANKAQNFEVV 290 GD+A +T GLKYDANNIYLA YS+T N T +G ++ G ANK QNFEV Sbjct: 239 IAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGY---DGGVANKTQNFEVT 295 Query: 291 AQYQFDFGLRPSVAYLQSKGKDISNGYGASYGDQDIVKYVDVGATYYFNKNMSTYVDYKI 350 AQYQFDFGLRP+V++L SKGKD++ + D+D+VKY DVGATYYFNKN STYVDYKI Sbjct: 296 AQYQFDFGLRPAVSFLMSKGKDLTYN-NVNGDDKDLVKYADVGATYYFNKNFSTYVDYKI 354 Query: 351 NLLDKND-FTRDAGINTDDIVALGLVYQF 378 NLLD +D F +DAGI+TDDIVALG+VYQF Sbjct: 355 NLLDDDDPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.9 bits (166), Expect = 2e-15 Identities = 24/114 (21%), Positives = 48/114 (42%), Gaps = 2/114 (1%) Query: 9 VLIVDDHPLMRRGIRQLLELDPAFYVVAEAGDGASAIDLANRIEPDLILLDLNMKGLSGL 68 +L+ DD +R + Q L A Y V + A+ + DL++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALSR--AGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DTLNALRRDGVTAQIIILTVSDSASDIYALIDAGADGYLLKDSDPEVLLEAIRK 122 D L +++ +++++ ++ + GA YL K D L+ I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.009 Identities = 21/74 (28%), Positives = 28/74 (37%), Gaps = 17/74 (22%) Query: 24 PGVKALDNVNLNVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSIIFQGKEVDFHSAK 83 PG K D + L G G GKSTL+ L G+ F D + K Sbjct: 591 PGCKF-DYSVV---------LEGTGGIGKSTLINTLVGLD-------FFSDTHFDIGTGK 633 Query: 84 EALENGISMVHQEL 97 ++ E +V EL Sbjct: 634 DSYEQIAGIVAYEL 647
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 51.8 bits (124), Expect = 3e-09 Identities = 64/402 (15%), Positives = 140/402 (34%), Gaps = 19/402 (4%) Query: 22 RVIICCFLVVMLDGFDTAAIGFIAPDIRTHWQLSASELAPLFGAGLLGLTAGALLCGPLA 81 +++I ++ + + PDI + + + A +L + G + G L+ Sbjct: 14 QILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLS 73 Query: 82 DRFGRKRVIELCVALFGALSLLSAFS-PDIETLVLLRFLTGLGLGGAMPNTIT-MTSEYL 139 D+ G KR++ + + S++ L++ RF+ G G A P + + + Y+ Sbjct: 74 DQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AAAFPALVMVVVARYI 132 Query: 140 PARRRGALVTLMFCGFTLGSAMGGIVSAQLVPLIGWHGILALGGILPLMLFFGLLFALPE 199 P RG L+ +G +G + + I W +L + I + + F L+ L + Sbjct: 133 PKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPF-LMKLLKK 191 Query: 200 SPRWQVRRQLPQAV---VARTVSAITGERYHDTH----------FFLHETAAVAKGSIRQ 246 R + + + V + Y + F H Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPG 251 Query: 247 LFAGRQLVITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQQASWVTAAFQVGGTLGA 306 L +I ++ + F ++ + +M ++ + + G Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG- 310 Query: 307 LLLGVLMDRLNPFRVLAVSYALGAVCIVMIGLSENG-LWLMALAIFGTGIGISGSQVGLN 365 + G+L+DR P VL + +V + W M + I G+S ++ ++ Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIS 370 Query: 366 ALTATLYPTQSRATGVSWSNAIGRCGAIVGSLSGGMMMALNF 407 + ++ Q G+S N G G ++++ Sbjct: 371 TIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412 Score = 41.8 bits (98), Expect = 4e-06 Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 1/169 (0%) Query: 251 RQLVITLMLWVVFFMSLLIIYLLSSWMPTLLNHRGIDLQQASWVTAAFQVGGTLGALLLG 310 R I + L ++ F S+L +L+ +P + N +WV AF + ++G + G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 311 VLMDRLNPFRVLAVSYALGAVCIVMIGLSENGLWLMALAIFGTGIGISGSQVGLNALTAT 370 L D+L R+L + V+ + + L+ +A F G G + + + A Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 371 LYPTQSRATGVSWSNAIGRCGAIVGSLSGGMMM-ALNFSFDTLFFVIAI 418 P ++R +I G VG GGM+ +++S+ L +I I Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITI 179
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 110 bits (276), Expect = 2e-31 Identities = 66/253 (26%), Positives = 115/253 (45%), Gaps = 12/253 (4%) Query: 3 KVAIVTASDSGIGKACALLLAQNGFDIGITWHSDERGAQETAKKAAQFGVRVETIHLDLS 62 K+A +T + GIG+A A LA G I ++ E+ + + A+ E D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE-ARHAEAFPADVR 67 Query: 63 QLPEGAQAIEHLIQRLGRVDVLVNNAGAMTKSAFIDMPFTQWRQIFTVDVDGAFLCAQIA 122 + + + +G +D+LVN AG + + +W F+V+ G F ++ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 ARHMIKQGEGGRIINITSVHEHTPLPQASSYTAAKHALGGLTKSMALELIEHHILVNAVA 182 +++M+ + G I+ + S P ++Y ++K A TK + LEL E++I N V+ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGAIATPM-------NDMDDSDIEPGSEP---SIPIARPGSTHEIASLVAWLCSEGASYT 232 PG+ T M + + I+ E IP+ + +IA V +L S A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGQSLIVDGGFML 245 T +L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 27.9 bits (62), Expect = 0.029 Identities = 8/39 (20%), Positives = 16/39 (41%), Gaps = 1/39 (2%) Query: 152 WLHDLDQHLRH-GVWLILAIVLVVGVRWWLKRRGKAEAR 189 L + +R G W++LA++ + R+ K Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQEKRRVS 253
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 36.3 bits (84), Expect = 9e-05 Identities = 33/146 (22%), Positives = 60/146 (41%), Gaps = 6/146 (4%) Query: 11 LALMLAVPFAPQAVAKTAATTAASQPEIASGSAMI-VDLNTNKVIYSNHPDLVRPIASIT 69 ++L+ +P A A + S+ +++ MI +DL + + + + D P+ S Sbjct: 9 ISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTF 68 Query: 70 KLMTAMVVLDARLPLDEILKVDISQTPEMKGVYSRV---RLNSEISRKNMLLLALMSSEN 126 K++ VL DE L+ I + YS V L ++ + A+ S+N Sbjct: 69 KVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDN 128 Query: 127 RAAASLAHYY--PGGYNAFIKAMNAK 150 AA L P G AF++ + Sbjct: 129 SAANLLLATVGGPAGLTAFLRQIGDN 154
>PF06580#Sensor histidine kinase Length = 349 Score = 217 bits (555), Expect = 4e-68 Identities = 60/216 (27%), Positives = 116/216 (53%), Gaps = 3/216 (1%) Query: 343 LGEGIAQLLSAQILAGQYERQKALLTQSEIKLLHAQVNPHFLFNALNTIKAVIRHDSEQA 402 L G + + + ++ ++++ L AQ+NPHF+FNALN I+A+I D +A Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKA 193 Query: 403 SQLVQYLSTFFRKNLKR-PSEIVTLADEIEHVNAYLQIEKARFQSRLQVQLDVPSTLSRQ 461 +++ LS R +L+ + V+LADE+ V++YLQ+ +F+ RLQ + + + Sbjct: 194 REMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDV 253 Query: 462 KLPAFTLQPIVENAIKHGTSQLLDTGNVAIRARREGQHLMLDIEDNAGLYQPSAG-SSGL 520 ++P +Q +VEN IKHG +QL G + ++ ++ + L++E+ L + S+G Sbjct: 254 QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313 Query: 521 GMSLVDKRLREHFGDDYGISVACEPDCFTRITLRLP 556 G+ V +RL+ +G + I ++ + + +P Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 49/215 (22%), Positives = 87/215 (40%), Gaps = 19/215 (8%) Query: 2 IKVLIVDDEPLARENLRILLQGQDDIEIVGECANAVEAIGAVHKLRPDVLFLDIQMPRIS 61 +L+ DD+ R L L V +NA + D++ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEMVGMLDPEHRPYI--VFLTAFD--EYAIKAFEEHAFDYLLKPIEEKRLEKTLHRLRQ 117 +++ + + RP + + ++A + AIKA E+ A+DYL KP + L + R Sbjct: 62 AFDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 118 ERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMDDVAFVSSRMSGVYVT--SSEGKEGFT 175 E ++ L ++Q + + G S +A + + +T S GK Sbjct: 121 EPKRRPSKLEDDSQDGMPLV---GRSAAMQEIYRVLARLMQTDLTLMITGESGTGK---- 173 Query: 176 ELTLRTLESRTPLLRCHRQFL-VNMAHLQEIRLED 209 EL R L R + F+ +NMA + +E Sbjct: 174 ELVARALHDYGK--RRNGPFVAINMAAIPRDLIES 206
>PF06291#Lambda prophage Bor protein Length = 102 Score = 27.7 bits (61), Expect = 0.010 Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 7 MALPLFALSLSVSITGCDQKNDTLQGKQNNMT 38 M LF+ +L++ ITGC Q+ T+ K +T Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVT 37
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 679 bits (1754), Expect = 0.0 Identities = 242/829 (29%), Positives = 390/829 (47%), Gaps = 28/829 (3%) Query: 13 AALLTSPAWAEEETFDTNFMFG-GLKGEKVSRYQIDSTKPMAGVYEMDVYVNKEWRGTYE 71 A +P + E F+ F+ +SR++ + + G Y +D+Y+N + T + Sbjct: 35 AFAAQAPLSSAELYFNPRFLADDPQAVADLSRFE-NGQELPPGTYRVDIYLNNGYMATRD 93 Query: 72 VNIQDDPDST----CISPDLIASLGIKFTPQSTTV---ENECIALKTVVHGGSVSYDTAA 124 V C++ +AS+G+ S ++ C+ L +++H + D Sbjct: 94 VTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQ 153 Query: 125 FNLYLSVPQAYVLEYEAGYASPETWDRGINAFYTSYYASEYYSHYKSGGSEKNTYANFVS 184 L L++PQA++ GY PE WD GINA +Y S + GG+ Y N S Sbjct: 154 QRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQS 213 Query: 185 GLNLLGWQLHSNANFSKSDN-----SAGKWQSNTLYLERDFPAVLGTMRLGEQYTSGDMF 239 GLN+ W+L N +S + + S KWQ +LERD + + LG+ YT GD+F Sbjct: 214 GLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIF 273 Query: 240 DTVRFRGVRFWRDMQMLPHSKQNFAPVVRGVAQSNALVTVEQNGFIVYQKEVPPGPFVFE 299 D + FRG + D MLP S++ FAPV+ G+A+ A VT++QNG+ +Y VPPGPF Sbjct: 274 DGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTIN 333 Query: 300 DLQLAGGGADLDVSVKEADGTVSRFIVPYSSVPNMVQPGVAKYDFAAGRSRIEGASQQTD 359 D+ AG DL V++KEADG+ F VPYSSVP + + G +Y AG R A Q+ Sbjct: 334 DIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQEKP 393 Query: 360 -FLQGTYQYGVNNLLTLYGGTMLASNYRSFTLGTGWNT-LIGAVSVDGTLSHSKQDNGDV 417 F Q T +G+ T+YGGT LA YR+F G G N +GA+SVD T ++S + Sbjct: 394 RFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQ 453 Query: 418 FDGESYQIAWNKYLPQSATHFSLAAYRYSSRDYRTFNDHVWANNRDNYRRDDDDIYDI-- 475 DG+S + +NK L +S T+ L YRYS+ Y F D ++ D + + Sbjct: 454 HDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKP 513 Query: 476 --ADYYENDFGRKNTFTLNINQTLPDGWGYFTASALWRDYWGRSGTGKDYQLSYSNTWQR 533 DYY + ++ L + Q L S + YWG S + +Q + ++ Sbjct: 514 KFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDEQFQAGLNTAFED 572 Query: 534 LSFTLSATQTYDSDNRE-DKRFNIYLSIPL--TWGVKENGGNRDIHLSNSTTFDDQGYEA 590 +++TLS + T ++ + D+ + ++IP R S S + D G Sbjct: 573 INWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMT 632 Query: 591 NNTSLSGTFGNRDQFNYTTNLS---QQRQEHQTTFGGSVTWNAPLATVGGSYSQSNQYHQ 647 N + GT + +Y+ +T ++ + YS S+ Q Sbjct: 633 NLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQ 692 Query: 648 VGGNIQGGLVAWADGVHLASRLNDTIAIINAPYLEGAAVQGRPYLRTNAKGYAVFEALTP 707 + + GG++A A+GV L LNDT+ ++ AP + A V+ + +RT+ +GYAV T Sbjct: 693 LYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATE 752 Query: 708 YRQNFISLDVSESESDVALLGNRKVTVPYRGAVVVVDFETETSKPFYFLARRADGEPLTF 767 YR+N ++LD + +V L VP RGA+V +F+ + +PL F Sbjct: 753 YRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLTH-NNKPLPF 811 Query: 768 GYEVEDDEGNNVGLVGQGSRVFIRTEKVPVSVKVATDKQQGLFCKITFD 816 G V + + G+V +V++ + V+V +++ C + Sbjct: 812 GAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQ 860
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 26.8 bits (59), Expect = 0.019 Identities = 10/43 (23%), Positives = 17/43 (39%), Gaps = 7/43 (16%) Query: 3 SKLLPCALLLATSFAWAAPA-------TTGIDQYELKSFIADF 38 ++L LLL +S++WA L+ + DF Sbjct: 10 KRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.0 bits (62), Expect = 0.041 Identities = 14/54 (25%), Positives = 23/54 (42%) Query: 41 LLALGASPAMVIDPVEARPFAAIANALLVNVGTLTASRAEAMRAAVESAYDAKT 94 L LGA +++ V + A A +V +TA+ E + AA +T Sbjct: 46 LFGLGAGLGVMVGRVGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRT 99
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.5 bits (87), Expect = 9e-05 Identities = 33/153 (21%), Positives = 53/153 (34%), Gaps = 20/153 (13%) Query: 253 FSEIFFMLALPFFTKRFGIKKVLLLGLITAAIRYGFFVYGGAETYFTYALLFLGILLHGV 312 + L + RFG + VLL+ L AA+ Y +L++G ++ G+ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGI 108 Query: 313 SYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYPQPVN 372 + V D R G ++ C GFG + G LGG+M P Sbjct: 109 TGATGAVAGAYIADI-TDGDERARHFGFMS-ACFGFGMVAGPVLGGLMGGFSPHAP---- 162 Query: 373 GLTFNWAGMWTFGAVMIAVIALLFMIFFRESNK 405 + A + + L ES+K Sbjct: 163 ---------FFAAAALNGLNFLTGCFLLPESHK 186 Score = 34.8 bits (80), Expect = 6e-04 Identities = 49/285 (17%), Positives = 84/285 (29%), Gaps = 15/285 (5%) Query: 29 LNKSGFSAGEIGWSYACTAIAAILSPILVGSVTDRFFSAQKVLAVLMFAGAVLMYFAAQQ 88 L S G A A+ ++G+++DRF +L L A A Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP 94 Query: 89 TTFVGFFPLLLAYSLTYMPTIALTNSIA-FANVPDVERDFPRIRVMGTIGWIASGLACGF 147 +V + ++A +T IA + + R F + G +A + G Sbjct: 95 FLWVLYIGRIVA-GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL 153 Query: 148 LPQMLGYNDISPTNIPLLITAASSALLGVFAFCLPDTPPKSTGKMDIKVMLGLDALVLLR 207 + SP + P AA + L + L K + + L A Sbjct: 154 M------GGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWA 206 Query: 208 DKN------FLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLA 261 VFF + +P A + IF G + + Sbjct: 207 RGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMI 266 Query: 262 LPFFTKRFGIKKVLLLGLITAAIRYGFFVYGGAETYFTYALLFLG 306 R G ++ L+LG+I Y + ++ L Sbjct: 267 TGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLA 311
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 25.8 bits (56), Expect = 0.046 Identities = 12/46 (26%), Positives = 19/46 (41%) Query: 60 SGAVASVSSGAAYTTALTVLGASFGMGGIGMMGICAGLYLSANGIR 105 SG++ +V S A ++ + M C GL L+ IR Sbjct: 136 SGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 85.6 bits (212), Expect = 1e-24 Identities = 30/118 (25%), Positives = 46/118 (38%), Gaps = 3/118 (2%) Query: 6 DRLLRQFSLKLNTDSIVFDENRLCSFIIDNRYRI-LLTSTNSEYIMIYGFCGRPPDNNNL 64 LL FS L +VFD++ C+ IIDN + + L E +++ G P + Sbjct: 7 KTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGLLE--PHKDIP 64 Query: 65 AFEFLNANLWFAENNGPHLCYDNNSQSLLLALNFSLNEGSVEKLECEIEVVIRSMENL 122 L L N GP L D S + + SV L+ E+ ++ M Sbjct: 65 QQCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMRGW 122
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.3 bits (185), Expect = 7e-18 Identities = 27/140 (19%), Positives = 65/140 (46%), Gaps = 2/140 (1%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLINHGDKVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + ++ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTIL-RRC 128 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 129 KPQRELQQQDAESPLMIDES 148 + +L+ + ++ S Sbjct: 124 RRPSKLEDDSQDGMPLVGRS 143
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.0 bits (70), Expect = 0.010 Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 14/66 (21%) Query: 187 RGLLAPVKRLVEGTHRLAAGDFTTRVTPTSADEL-----------GKLAQDFNQLASTLE 235 L+A V+ V H LA + P S + L G L N+LA E Sbjct: 104 SQLMAAVRSKVMEGHSLAD---AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTE 160 Query: 236 KNQQMR 241 + QQMR Sbjct: 161 QRQQMR 166
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 124 bits (313), Expect = 3e-33 Identities = 95/450 (21%), Positives = 199/450 (44%), Gaps = 25/450 (5%) Query: 20 FMQSLDTTIVNTALPSMAKSLGESPLHMHMVVVSYVLTVAVMLPASGWLADKIGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 AAIVLFTLGSLFCALSGT-LNQLVLARVLQGVGGAMMVPVGRLTVMKIVPRAQYMAAMTF 138 I++ GS+ + + + L++AR +QG G A + + V + +P+ A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQIGPLLGPALGGVLVEYASWHWIFLINIPVGIVGAIATFM-LMPNYTIETRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ + + M L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 PGFLLLAIGMAVLTLALDGSKSMGISPWTLAGLAAGGAAAILLYLLHAKKNSGALFSLRL 257 G +L+++G+ L + L + L+++ H +K + L Sbjct: 202 KGIILMSVGIVFFMLFTTSYSISFLIVSVL---------SFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTPTFSLGLLGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+L M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQIVNRFGYRRVLVATTLGLALVSLLFMSVALL----GWYYLLPLVLLLQGMVNSARFS 372 +V+R G VL +G+ +S+ F++ + L W+ + +V +L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDTLASSGNSLLSMIMQLSMSIGVTIAGMLL--GMFGQQHIGIDSSATHH 430 ++T+ L A +G SLL+ LS G+ I G LL + Q+ + ++ + + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 431 VFMYTWLCMAVIIALPAIIFARVPNDTQQN 460 ++ L + II + ++ V +Q++ Sbjct: 428 LYSNLLLLFSGIIVISWLVTLNVYKHSQRD 457
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 881 bits (2277), Expect = 0.0 Identities = 282/1035 (27%), Positives = 502/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILIAAAITLCGILGFRLLPVAPLPQVDFPVIMVSASLPGASPETMASSVAT 65 FI RP+ ++A + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVNEMTSSS-SLGSTRIILEFNFDRDINGAARDVQAAINAAQSLLPGGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSES--WSQGKLYDFASTQLAQTIAQIDGVGDVDVGGSSL 182 + S + +M+ S++ +Q + D+ ++ + T+++++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDEVREAIDSANVRRPQGAIEDSV------HRWQIQTNDELK 236 A+R+ L+ L ++ +V + N + G + + I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGAAVRLGDVASVTDSVQDVRNAGMTNANPAILLMIRKLPEANIIQ 295 E+ + + N +G+ VRL DVA V ++ N PA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDGIRAKLPELRAMIPAAIDLQIAQDRSPTIRASLQEVEETLAISVALVILVVFLFLRS 355 T I+AKL EL+ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATLIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RATLIP +AVPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVISMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LVVSLTLTPMMCGWMLKSSKPRTQPRKRGVG----RLLVALQQGYGTSLKWVLNHTRLVG 530 ++V+L LTP +C +LK K G Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVFLGTVALNIWLYIAIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 +++ VA + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVNNVTGFT-GGSRVNSGMMFITLKPRGER---KETAQQIIDRLRVKLAKEPGAR 641 + +V V GF+ G N+GM F++LKP ER + +A+ +I R +++L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQANASYQYTLLSDSLAALREWEPKIRKALSAL-----PQLADVNSD 696 + + I G ++ L D + + R L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QQDNGAEMNLIYDRDTMSRLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 SQDISALEKMFVINRDGKAIPLSYFAQWRPANAPLSVNHQGLSAASTIAFNLPTGTSLSQ 816 ++K++V + +G+ +P S F + + I GTS Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ATEAINRTMTQLGVPPTVRGSFSGTAQVFQQTMNSQLILIVAAIATVYIVLGILYESYVH 876 A + ++L P + ++G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRSGG 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + G Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPEQAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 +A A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 890 bits (2302), Expect = 0.0 Identities = 292/1036 (28%), Positives = 504/1036 (48%), Gaps = 29/1036 (2%) Query: 13 SRLFILRPVATTLLMAAILLAGIIGYRFLPVAALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L +++AG + LPVA P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVVTLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ +TL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPIYSKVNPADPPIMTLAVTSNAMPMTQVE--DMVETRVAQKISQVSGVGLVTLAGG 189 + I S + +M S+ TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAVAALGLTSETVRTAITGANVNSAKGSLDGP------ERAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G + ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSADEYRRLII-AYQNGAPVRLGDVATVEQGAENSWLGAWANQAPAIVMNVQRQPGANI 302 ++ +E+ ++ + +G+ VRL DVA VE G EN + A N PA + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 IATADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVRDTQFELMLAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAVTLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F++T+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQQSLRKQNRFSRACERMFDRVIASYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S + + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVAFATLLLSVMLWIVIPKGFFPVQDNGIIQGTLQAPQSSSYASMAQRQRQVAERILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV + L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTTFVGVDGANPTLNSARLQINLKPLDARDDR---VQQVISRLQTAVATIPG 653 + V+S+ T G + N+ ++LKP + R+ + VI R + + I Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 654 VALYLQPTQDLTIDTQVSRTQYQFTLQ---ATTLDALSHWVPKL-QNALQSLPQLSEVSS 709 ++ P I + T + F L DAL+ +L A Q L V Sbjct: 660 G--FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDRGLAAWVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTA 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 STPGLAALETIRLTSRDGGTVPLSAIARIEQRFAPLSINHLDQFPVTTFSFNVPEGYSLG 829 ++ + + S +G VP SA + + + P G S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAILDTEKTLALPADITTQFQGSTLAFQAALGSTVWLIVAAVVAMYIVLGVLYESFI 889 DA+ + + LPA I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALIIAGSELDIIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + D+ ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPRDAIFQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIAMVGGLLVSQV 1009 G +A A +R RPILMT+LA +LG LPL +S G G+ + +GI ++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 107 bits (268), Expect = 2e-28 Identities = 81/361 (22%), Positives = 127/361 (35%), Gaps = 58/361 (16%) Query: 6 LITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPH--------SCNPK 57 L+TG G G ++++ LLE G++V GI + N Y D P Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLND------YYDVSLKQARLELLAQPG 53 Query: 58 FHLHYGDLTDASNLTRILQEVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAI 117 F H DL D +T + + V+ V S E+P AD + G L +LE Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 118 RFLGLEKKTRFYQASTSELYGLVQEIPQKETTPF-YPRSPYAVAKLYAYWITVNYRESYG 176 R ++ AS+S +YGL +++P +P S YA K + Y YG Sbjct: 114 RHNKIQ---HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 177 IYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVRM 236 + A F P K T+A+ G +Y RD+ + D Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLE---GKSIDVY-NYGKMKRDFTYIDD---- 222 Query: 237 QWMMLQQEQPEDFVIATGVQYSVRQFVELAAAQLGIKLRFEGEGINEKGIVVSVTGHDAP 296 IA + +R + A + + V G+ +P Sbjct: 223 --------------IAEAI---IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSP 265 Query: 297 GVKPGDVIVAV--------DPRY--FRPAEVETLLGDPSKAHEKLGWKPEITLSEMVSEM 346 V+ D I A+ +P +V D +E +G+ PE T+ + V Sbjct: 266 -VELMDYIQALEDALGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNF 324 Query: 347 V 347 V Sbjct: 325 V 325
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 87.9 bits (218), Expect = 7e-22 Identities = 64/344 (18%), Positives = 128/344 (37%), Gaps = 47/344 (13%) Query: 5 RIFVAGHRGMVGSAIVRQLAQRG-------------DVEL------VLRTRD----ELDL 41 + V G G +G + ++L + G DV L +L ++DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 42 LDGRAVQAFFAGAGIDQVYLAAAKVGGIVANNTYPADFIYENMMIESNIIHAAHLHNVNK 101 D + FA ++V+++ + + + P + N+ NI+ + + Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 102 LLFLGSSCIYPKLARQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSV 161 LL+ SS +Y + P + P + YA K A + +Y+ YG + Sbjct: 121 LLYASSSSVYGLNRKMPFSTD---DSVDHPVS-LYAATKKANELMAHTYSHLYGLPATGL 176 Query: 162 MPTNLYGPHDNFHPDNSHVIPALLRRFHEAAQSHAPEVVVWGSGTPMREFLHVDDMAAAS 221 +YGP PD AL + + + +V + G R+F ++DD+A A Sbjct: 177 RFFTVYGPWGR--PDM-----ALFKFTKAMLEGKSIDV--YNYGKMKRDFTYIDDIAEAI 227 Query: 222 IHVMELA----REVWQENTAPMLSH-----INVGTGVDCTIRELAQTIAKVVGYQGRVVF 272 I + ++ + E P S N+G + + Q + +G + + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 273 DAAKPDGTPRKLLDVTRLHQ-LGWYHEISLEAGLAGTYQWFLEN 315 +P D L++ +G+ E +++ G+ W+ + Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 94.1 bits (234), Expect = 4e-24 Identities = 73/333 (21%), Positives = 123/333 (36%), Gaps = 60/333 (18%) Query: 4 NVLLIGASGFVGT----RLLE-----TAVDDFN-----------IKNLDKQQSHFYPEIT 43 L+ GA+GF+G RLLE +D+ N ++ L + F+ Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHK--- 58 Query: 44 RIGDVRDQQILDQTLA--GFDTVVLLAAEH--RDDVSPTSLYYDVNVQGTRNVLAAMEKN 99 D+ D++ + A F+ V + R + Y D N+ G N+L N Sbjct: 59 --IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 100 GVKNIIFTSSVAVYGLNKKNP-DETHPHD-PFNHYGKSKWQAEEVLREWHA--KAPNERS 155 ++++++ SS +VYGLN+K P D P + Y +K E + + P Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLP---- 172 Query: 156 LTIIRPTVIFGERNRGN--VYNLLKQIAGGKFAMV-GPGTNYKSMAYVGNIVEFIKFKLK 212 T +R ++G R + ++ K + GK V G + Y+ +I E I Sbjct: 173 ATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQD 232 Query: 213 N-----------------VTAGYEVYNYVDKPDLNMNQLVAEVEQSLGKKIPSMHLPYPL 255 A Y VYN + + + + +E +LG + LP Sbjct: 233 VIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQP 292 Query: 256 GMLGGYCFDI--LSKVTGKKYAVS-SVRVKKFC 285 G + D L +V G + VK F Sbjct: 293 GDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 183 bits (465), Expect = 2e-57 Identities = 81/351 (23%), Positives = 153/351 (43%), Gaps = 39/351 (11%) Query: 1 MAILVTGGAGYIGTHTIISLLDKGYDIVVIDNFSNSSKDAL---TQVEKISAKKINFYHG 57 M LVTG AG+IG H LL+ G+ +V IDN N D ++E ++ F+ Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNL-NDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIRDRHVLKDIFSQNSISDVIHFAGLKAVGESVTSPLKYYDNNISGTLCLLNEMLLFNVK 117 D+ DR + D+F+ V AV S+ +P Y D+N++G L +L ++ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119 Query: 118 SIIFSSSATVYGVPKTLPIKESDPLGQITNPYGRTKIMAENILKDLTKAIPDFRATILRY 177 ++++SS++VYG+ + +P D + + Y TK E + + + AT LR+ Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPATGLRF 178 Query: 178 FNPVGAHPSGLIGENPKGIPN-NLFPVISQTIAGRNQSVNIFGSDYATPDGTGIRDYIHV 236 F G P G P+ LF + G+ S++++ G RD+ ++ Sbjct: 179 FTVYG----------PWGRPDMALFKFTKAMLEGK--SIDVYN------YGKMKRDFTYI 220 Query: 237 MDLAAGHFSALDKQREGKN---------------FKVYNLGTGKGYSVLQIIKEFENQIN 281 D+A D ++VYN+G ++ I+ E+ + Sbjct: 221 DDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG 280 Query: 282 KKIKIDLCPRREGDIAQCWSSPDLALEELSWKANLSLEDMIRDTLNWLSKY 332 + K ++ P + GD+ + + E + + +++D +++ +NW + Sbjct: 281 IEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 29.3 bits (65), Expect = 0.028 Identities = 11/49 (22%), Positives = 19/49 (38%), Gaps = 6/49 (12%) Query: 296 ASAMRSHWDVENKLHWRLDVAMNEDDCRIRRGNSAELFSGIRHIAVNIL 344 S D N+ + + ++ R GNS E +G+ A+N Sbjct: 197 GSNFSDRADEANRKMFEHNAKLD------RWGNSMEFINGVAAGALNPF 239
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 582 bits (1502), Expect = 0.0 Identities = 201/395 (50%), Positives = 279/395 (70%), Gaps = 5/395 (1%) Query: 4 KIMAINAGSSSLKFQLLEMPQGDMLCQGLIERIGMADAQVTIKTHSQKWQETVPVADHRD 63 KI+ IN GSSSLK+QL+E G++L +GL ERIG+ D+ +T + +K + + DH+D Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKD 61 Query: 64 AVTLLLEKLLG--YQIINSLRDIDGVGHRVAHGGEFFKDSTLVTDETLAQIERLAELAPL 121 A+ L+L+ L+ Y +I + +ID VGHRV HGGE+F S L+TD+ L I ELAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 122 HNPVNALGIHVFRQLLPDAPSVAVFDTAFHQTLDEPAYIYPLPWHYYAELGIRRYGFHGT 181 HNP N GI Q++PD P VAVFDTAFHQT+ + AY+YP+P+ YY + IR+YGFHGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 182 SHKYVSGVLAEKLGVPLSALRVICCHLGNGSSICAIKNGRSVNTSMGFTPQSGVMMGTRS 241 SHKYVS AE L P+ +L++I CHLGNGSSI A+KNG+S++TSMGFTP G+ MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 242 GDIDPSILPWIAQRENKTPQQLNQLLNNESGLLGVSGVSSDYRDVEQAA-NTGNRQAKLA 300 G IDPSI+ ++ ++EN + +++ +LN +SG+ G+SG+SSD+RD+E AA G+++A+LA Sbjct: 242 GSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLA 301 Query: 301 LTLFAERIRATIGSYIMQMGGLDALVFTGGIGENSARARSAVCHNLQFLGLAVDEEKNQR 360 L +FA R++ TIGSY MGG+D +VFT GIGEN R + L+FLG +D+EKN+ Sbjct: 302 LNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKV 361 Query: 361 NA--TFIQTENALVKVAVINTNEELMIAQDVMRVA 393 I T ++ V V V+ TNEE MIA+D ++ Sbjct: 362 RGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIV 396
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 30.6 bits (69), Expect = 0.010 Identities = 8/39 (20%), Positives = 17/39 (43%) Query: 190 SDFTDALAEKAAKLVFQYLPTAVEKGDCVATRGKMHNAS 228 SDF+ ++ K LV+ +L + + + G + Sbjct: 518 SDFSKVVSSKDKSLVYSFLDNLMSYLETIKNDGPIDTDK 556
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 26.6 bits (58), Expect = 0.017 Identities = 14/32 (43%), Positives = 21/32 (65%), Gaps = 1/32 (3%) Query: 39 QAIAPQYKPWFQPLYEPASGEIESLLFTLQGS 70 + IAP+YK +FQ L E + +++ LL T Q S Sbjct: 739 KQIAPEYKNYFQYLKERITNQVQ-LLLTHQKS 769
>PF03627#PapG Length = 336 Score = 36.9 bits (85), Expect = 1e-04 Identities = 22/93 (23%), Positives = 34/93 (36%), Gaps = 8/93 (8%) Query: 327 DDHVLDAVLPPDIP-------IPSIAEVQRALYDATKAVSGMPGEEVKQRLRTGTVVTTD 379 DD + LP D+P IP + +QR A +P K R ++ Sbjct: 152 DDIIFKVALPADLPLGDYSVTIPYTSGMQRHFASYLGARFKIPYNVAKTLPRENEMLFLF 211 Query: 380 DRNWELRYSASALRFNLSRAVAIDMESATIAAQ 412 R SA +L ++I+ + AAQ Sbjct: 212 KNIGGCRPSAQSLEIKHGD-LSINSANNHYAAQ 243
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 213 bits (543), Expect = 5e-71 Identities = 231/260 (88%), Positives = 246/260 (94%) Query: 1 MIQVTSEQWLYWLHLYFWPLLRVLALISTAPILSERAIPKRVKLGLGIMITLVIAPSLPA 60 M+QVTSEQWL WL+LYFWPLLRVLALISTAPILSER++PKRVKLGL +MIT IAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDTPLFSIAALWLAMQQILIGIALGFTMQFAFAAVRTAGEFIGLQMGLSFATFVDPGSHL 120 ND P+FS ALWLA+QQILIGIALGFTMQFAFAAVRTAGE IGLQMGLSFATFVDP SHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLAMLLFLTFNGHLWLISLLVDTFHTLPIGSNPVNSNAFMALARAGGLIF 180 NMPVLARIMDMLA+LLFLTFNGHLWLISLLVDTFHTLPIG P+NSNAF+AL +AG LIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPVITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGIMLMAALMPLIAPFC 240 LNGLMLALP+ITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGI LMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEIFNLLADIVSEMPI 260 EHLFSEIFNLLADI+SE+P+ Sbjct: 241 EHLFSEIFNLLADIISELPL 260
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.5 bits (165), Expect = 1e-18 Identities = 23/78 (29%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALITGLIISILQAATQINEMTLSFIPKIVAVFIAII 63 + ++ G +A+ + L L+ +VA I GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 330 bits (847), Expect = e-117 Identities = 225/245 (91%), Positives = 233/245 (95%) Query: 1 MRRLLFLSLAGLWLFSPAAAAQLPGLISQPLAGGGQSWSLSVQTLVFITSLTFLPAILLM 60 MRRLL ++ LWL +P A AQLPG+ SQPL GGGQSWSL VQTLVFITSLTF+PAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEQK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSE+K Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALDKGAQPLRAFMLRQTREADLALFARLANSGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEAL+KGAQPLR FMLRQTREADL LFARLAN+GPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 209 bits (534), Expect = 2e-73 Identities = 136/137 (99%), Positives = 136/137 (99%) Query: 1 MSDMNNPSDENTGALDDLWADALNEQKATTNKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 MSDMNNPSDENTGALDDLWADALNEQKATT KSAADAVFQQLGGGDVSGAMQDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 384 bits (987), Expect = e-136 Identities = 86/324 (26%), Positives = 148/324 (45%), Gaps = 10/324 (3%) Query: 5 ILSQAEIDALLNGDS--DTKDEPTPGIASDSDIRPYDPNTQRRVVRERLQALEIINERFA 62 +LSQ EID LL S D E I+ I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 63 RQFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 122 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 123 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 182 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 183 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 240 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 241 HEDQNWRDNLVRQVQHSELELVANFADIPLRLSQILKLKPGDVLPIEKP---DRIIAHVD 297 + L ++ ++++VA + L + IL L+ GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 298 GVPVLTSQYGTVNGQYALRVEHLI 321 Q G V + A ++ I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 405 bits (1041), Expect = e-142 Identities = 193/411 (46%), Positives = 232/411 (56%), Gaps = 40/411 (9%) Query: 1 MITLPQLITTDTDMTAGLTSGKTTGSAEDFLALLAGALGADGAQGKDARITLADLQAAGG 60 MI L LIT D D T L GK + +A+DFLALL+ AL + K A L Sbjct: 1 MIRLAPLITADVDTTT-LPGGKASDAAQDFLALLSEALAGETTTDKAAPQLL-------- 51 Query: 61 KLSKGLLTQHGEPGQAVKLADLLAQKAN---ATDETLTDLTQAQHLLSTLTPSLKTSALA 117 ++ T GEP + ++D AQ+AN DET + Q + LT + + A Sbjct: 52 -VATDKPTTKGEPLISDIVSD--AQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAA 108 Query: 118 ALSKTAQHDEKTPALSDEDLASLSALFAMLPGQPVATPVAGETPAENHIALPSLLRGDMP 177 K DEK L+++ ASLSALFAMLPG V D P Sbjct: 109 VADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKVT-----------------DAP 151 Query: 178 SAPQEETHTLSFSEHEKGKTEASLTRASDDRATGPVLTPLVVAAAATSAKVEVDSPSAPV 237 S F++ T LT A D A G PL A +K EV S +PV Sbjct: 152 STVLPTEKPTLFTK----LTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPV 207 Query: 238 THGAAMPTLSSATAQPQPLPVASAPVLSAPLGSHEWQQTFSQQVMLFTRQGQQSAQLRLH 297 T AA P ++ QP LP +APVLSAPLGSHEWQQ+ SQ + LFTRQGQQSA+LRLH Sbjct: 208 T-AAASPLITPHQTQP--LPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLH 264 Query: 298 PEELGQVHISLKLDDNQAQLQMVSPHSHVRAALEAALPMLRTQLAESGIQLGQSSISSES 357 P++LG+V ISLK+DDNQAQ+QMVSPH HVRAALEAALP+LRTQLAESGIQLGQS+IS ES Sbjct: 265 PQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGES 324 Query: 358 FAGQQQ-SSSQQQSSRAQHTDAFGAEDDIALAAPASLQAAARGNGAVDIFA 407 F+GQQQ +S QQQS R + + EDD L P SLQ GN VDIFA Sbjct: 325 FSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQGRVTGNSGVDIFA 375
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 206 bits (526), Expect = 4e-72 Identities = 130/147 (88%), Positives = 138/147 (93%) Query: 1 MAQHGALETLKDLAEKEVDDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRSNLNTDMGNG 60 MA+HGAL TLKDLAEKEV+DAARLLGEMRRGCQQAEEQLKMLIDYQNEYR+NLN+DM G Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 IASNRWINYQQFIQTLEKAIEQHRLQLTQWTQKVDLALKSWREKKQRLQAWQTLQDRQTA 120 I SNRWINYQQFIQTLEKAI QHR QL QWTQKVD+AL SWREKKQRLQAWQTLQ+RQ+ Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRMDQKKMDEFAQRAAMRKPE 147 AALLAENR+DQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>PilS_PF08805#PilS N terminal Length = 185 Score = 27.2 bits (60), Expect = 0.032 Identities = 5/34 (14%), Positives = 14/34 (41%), Gaps = 2/34 (5%) Query: 112 WTLITSI--LIIIAVAVVLAISSMNVAFRSLNIN 143 TL+ + + +I V A ++ ++ + Sbjct: 28 ATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSS 61
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.011 Identities = 13/60 (21%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 60 WLCIDYLWVSESARSNGLGSKLMEMAEKEGLRKGCVHGLVDTFSFQ--ALPFYEKQGYIL 117 + I+ + V++ R G+G+ L+ A + +++T A FY K +I+ Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>SOPEPROTEIN#Salmonella type III secretion SopE effector protein signature. Length = 239 Score = 397 bits (1020), Expect = e-144 Identities = 163/237 (68%), Positives = 192/237 (81%) Query: 2 TNITLSTQHYRIHRSDVEPVKEKTTEKDIFAKSITAVRNSFISLSTSLSDRFSLHLQTDI 61 T ITLS Q++RI + + +KEK+TEK+ AKSI AV+N FI L + LS+RF H T+ Sbjct: 1 TKITLSPQNFRIQKQETTLLKEKSTEKNSLAKSILAVKNHFIELRSKLSERFISHKNTES 60 Query: 62 PTTHFHRGSASEGRAVLTSKTVKDFMLQKLNSLDIKGNASKDPAYARQTCEAILAAVYSN 121 THFHRGSASEGRAVLT+K VKDFMLQ LN +DI+G+ASKDPAYA QT EAIL+AVYS Sbjct: 61 SATHFHRGSASEGRAVLTNKVVKDFMLQTLNDIDIRGSASKDPAYASQTREAILSAVYSK 120 Query: 122 NKDQCCKLLISKGNSITPFLKEIGEAAQNAGLPGEMKNGVFTPGGAGANPFVVPLIAAAS 181 NKDQCC LLISKG +I PFL+EIGEAA+NAGLPG KN VFTP GAGANPF+ PLI++A+ Sbjct: 121 NKDQCCNLLISKGINIAPFLQEIGEAAKNAGLPGTTKNDVFTPSGAGANPFITPLISSAN 180 Query: 182 IKYPHMFINHNQQVSFKAHAEKIVMKEVTPLFNKGTMPTPQQFQLTIENIANKYLQN 238 KYP MFIN +QQ SFK +AEKI+M EV PLFN+ MPTPQQFQL +ENIANKY+QN Sbjct: 181 SKYPRMFINQHQQASFKIYAEKIIMTEVAPLFNECAMPTPQQFQLILENIANKYIQN 237
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.1 bits (70), Expect = 0.016 Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 16/81 (19%) Query: 288 LGAIESLLCAV----VL---DGMTGTKHKANSELIGQGLGNM---VAPFF------GGIT 331 L + +L A+ +L D T TK A EL + LGN+ ++ + G++ Sbjct: 242 LDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLS 301 Query: 332 ATAAIARSAANVRAGATSPVS 352 +AA A A+ A SP+S Sbjct: 302 TSAAAAGLIASAVTLAISPLS 322
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 52.0 bits (124), Expect = 4e-10 Identities = 52/260 (20%), Positives = 99/260 (38%), Gaps = 22/260 (8%) Query: 4 LSGKRILVTGVASKLSIAYGIAQAMHREGAEL-AFTYQNDKLKGRVEEFAAQLGSSIVLP 62 + GK +TG A I +A+ + +GA + A Y +KL+ V A+ + P Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 63 CDVAEDASIDAMFAELGNVWPKFDGFVHSIGF---APGDQLDGDYVNAVTREGFKIAHDI 119 DV + A+ID + A + D V+ G L + A F + Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEAT----FSVN--- 116 Query: 120 SSYSFVAMAKACRTMLNP-GSALLTLSYLGAERAIPNYNVMGLAKASLEANVRYMANAMG 178 S+ F A + M++ +++T+ A + +KA+ + + + Sbjct: 117 STGVFNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 179 PEGVRVNAISAGPIRTLAASGI--------KDFRKMLAHCEAVTPIRRTVTIEDVGNSAA 230 +R N +S G T + + + L + P+++ D+ ++ Sbjct: 177 EYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVL 236 Query: 231 FLCSDLSAGISGEVVHVDGG 250 FL S + I+ + VDGG Sbjct: 237 FLVSGQAGHITMHNLCVDGG 256
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.007 Identities = 9/16 (56%), Positives = 14/16 (87%) Query: 38 LVGESGSGKSLIAKAI 53 + GESG+GK L+A+A+ Sbjct: 165 ITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 344 bits (884), Expect = e-118 Identities = 125/345 (36%), Positives = 176/345 (51%), Gaps = 22/345 (6%) Query: 2 AEFKDNLLGEANRFLEVLEQVSRLAPLDKPVLIIGERGTGKELIANRLHYLSSRWQGPLI 61 ++ L+G + E+ ++RL D ++I GE GTGKEL+A LH R GP + Sbjct: 133 SQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFV 192 Query: 62 SLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMLVQEKLL 121 ++N AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LL Sbjct: 193 AINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLL 252 Query: 122 RVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVKEGTFRADLLDRLAFDVVQLPPLRE 181 RV++ GE VGG P++ +VR+V ATN DL + +G FR DL RL ++LPPLR+ Sbjct: 253 RVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRD 312 Query: 182 RQSDIMLMAEHFAIQMCRELRLPLFPGFTDRAKETLLHYAWPGNVRELKNVVERSVYRHG 241 R DI + HF Q +E F A E + + WPGNVREL+N+V R + Sbjct: 313 RAEDIPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYP 370 Query: 242 SSE--------HPLDEIVIDPFQRHPA------------EPPAPALPSATATPDLPLKLR 281 EI P ++ A E S Sbjct: 371 QDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYD 430 Query: 282 EFQLQQEKALLQRSLQQAKFNQKRAADLLALTYHQFRALLKKHQL 326 + E L+ +L + NQ +AADLL L + R +++ + Sbjct: 431 RVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.6 bits (64), Expect = 0.019 Identities = 19/104 (18%), Positives = 43/104 (41%), Gaps = 5/104 (4%) Query: 40 LVEVRSNSARALAEKKQLSRRIEQATAQQTEWQEKAELA-LRKDKDDLARAALIEKQKLT 98 + + R + +L K+ +++ + + EL + + + L K++ Sbjct: 232 VEKSRLDDFSSLLHKQAIAK-HAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 99 DLIATLEQEVTLVDDTLARMKKEIGELENKLSETRARQQALMLR 142 + + E+ D L + IG L +L++ RQQA ++R Sbjct: 291 LVTQLFKNEIL---DKLRQTTDNIGLLTLELAKNEERQQASVIR 331
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 25.7 bits (56), Expect = 0.015 Identities = 6/43 (13%), Positives = 14/43 (32%) Query: 30 AGRGELSQSEQQRLLQLTDDAQRMRERIQALEDILDAEHPNWR 72 AG+ + + + A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.3 bits (213), Expect = 2e-22 Identities = 68/249 (27%), Positives = 112/249 (44%), Gaps = 24/249 (9%) Query: 7 KSVLVLGGSRGIGAAIVRRFSADGASVV-FSYAGSR----EAAEKLAAETGSTAIQTDSA 61 K + G ++GIG A+ R ++ GA + Y + ++ K A + A D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARH-AEAFPADVR 67 Query: 62 DRDAIISLV----REYGPLDILVVNAGVALFGDALEQDSDAIDRLFRINIHAPYHASVEA 117 D AI + RE GP+DILV AGV G + + F +N ++AS Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 ARNMP--EGGRIIIIGSVNGDRMPVPGMAAYAASKSALQGLARGLARDFGPRGITINVVQ 175 ++ M G I+ +GS N +P MAAYA+SK+A + L + I N+V Sbjct: 128 SKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 176 PGPIDTDI--------NPEDGPMKELMHSF---MAIKRHGRPEEVAGMVAWLAGPEASFV 224 PG +TD+ N + +K + +F + +K+ +P ++A V +L +A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 225 TGAMHTIDG 233 T +DG Sbjct: 247 TMHNLCVDG 255
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 3e-08 Identities = 14/115 (12%), Positives = 40/115 (34%), Gaps = 5/115 (4%) Query: 6 SRTPGRPRQFDPEQAIETAQHLFHSRGYDAVSVADLTKAFGINPPSFYAAFGSKLGLYTR 65 +T ++ + ++ A LF +G + S+ ++ KA G+ + Y F K L++ Sbjct: 3 RKTKQEAQE-TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 66 VLK----RYRMTDAIPLGALLRHDRPTAKCLIDVLMEAARRYAADPDATGCLVLE 116 + + + + ++ ++E+ + + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK 116
>adhesinb#Adhesin B signature. Length = 310 Score = 28.3 bits (63), Expect = 0.002 Identities = 10/48 (20%), Positives = 18/48 (37%), Gaps = 6/48 (12%) Query: 1 MQKCSLITVLSLSVLMLAGCTTTYTMTTRTGDIIETQGKPEVDTATGM 48 M+KC + +L L+ + LA C++ K V + Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQ------KSSTETGSSKLNVVATNSI 42
>INTIMIN#Intimin signature. Length = 939 Score = 217 bits (554), Expect = 2e-62 Identities = 117/409 (28%), Positives = 187/409 (45%), Gaps = 21/409 (5%) Query: 29 SDNEIQSWIAGTASSISPHLQEGTLE-DYAKGKIKALPGQAANHLVNEGMKSAFPAIIFR 87 +D++ ++ A A+S+ LQ +L DYAK + G A+ + ++ A Sbjct: 158 TDDKALNYAAQQAASLGSQLQSRSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTA---- 213 Query: 88 GGVNLEDGAKYRSSEFDMFIPVEETTSSLLFGQLGFRDHDSSSFDGRTYVNVGVGYRQEV 147 VNL+ G + S D +P ++ L FGQ+G R DS R N+G G R + Sbjct: 214 -EVNLQSGNNFDGSSLDFLLPFYDSEKMLAFGQVGARYIDS-----RFTANLGAGQRFFL 267 Query: 148 NGWLLGVNTFLDADIRYSHLRGGIGGEVYKDSLAFSGNYYFPLTGWKTSAVHELHDERPA 207 +LG N F+D D + R GIGGE ++D S N YF ++GW S + +DERPA Sbjct: 268 PENMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPA 327 Query: 208 YGFDLRTKGTLPDFPWFSGELTYEQYYGDKVDLLGNGTLSRNPRAAGAALVWNPVPLLEV 267 GFD+R G LP +P +L YEQYYGD V L + L NP AA + + P+PL+ + Sbjct: 328 NGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTM 387 Query: 268 RAGYRDAGNGGSQAEGGLRVNYSFGTPLHEQLDYRNV-GAPSNTTNRRAFVDRNYDIVMA 326 YR + ++ Y F P +Q++ + V + + +R V RN +I++ Sbjct: 388 GIDYRHGTGNENDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILE 447 Query: 327 YREQAS-KIRITAMPVSGLSGTLVTLMATVDSRYPIEKVEWSGDAELLAGLQLQGSLGSG 385 Y++Q + I ++G + + V S+Y ++++ W A G Q+Q S Sbjct: 448 YKKQDILSLNIPH-DINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQS 506 Query: 386 -----LILPQLPLTATDGQEYSLYLTVTDSRGTRVTSERIPVRVTQDET 429 ILP Y + D G + + + V + Sbjct: 507 AQDYQAILP--AYVQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQ 553
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 148 bits (375), Expect = 9e-43 Identities = 95/369 (25%), Positives = 167/369 (45%), Gaps = 6/369 (1%) Query: 20 RRILPVFLLVGLYAASTAAVMSVLPFYIREMGGSPLII---GIIIATEAFSQFCAAPLIG 76 R ++ + V L A +M VLP +R++ S + GI++A A QF AP++G Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 77 HLSDRVGRKRILIITLTIAAISLLLLANAQCILFILLARTLFGISAGNLSAAVAYIADCT 136 LSDR GR+ +L+++L AA+ ++A A + + + R + GI+ + A AYIAD T Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT 124 Query: 137 HVRNRRQAIGILTGCIGLGGIVGAGVSGWLSRISLSAPIYAAFILVLGSALVAIWGLKDP 196 R + G ++ C G G + G + G + S AP +AA L + L + L + Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 197 STTSRTADKIAAFSARAILKMPVLRVLIIVMLCHFFAYGMYSSQLPVFLSDTFIWNGLPF 256 R + A + A + ++ ++ FF + Q+P L F + + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLV-GQVPAALWVIFGEDRFHW 243 Query: 257 GPKALSYLLMADGVINIFVQLFLLGWVSQYFSERKLIILIFALLCTGFLTAGIATTIPVL 316 + L A G+++ Q + G V+ ER+ ++L TG++ AT + Sbjct: 244 DATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMA 303 Query: 317 IFAIVCISIADALAKPTYLAALSVHVSPARQGIVIGTAQALIAIADFISPVLGGFVLGYA 376 +V + + + P A LS V RQG + G+ AL ++ + P+L + + Sbjct: 304 FPIMVLL-ASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 377 LYGVWIGIA 385 + W G A Sbjct: 363 I-TTWNGWA 370
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 55.2 bits (133), Expect = 2e-10 Identities = 67/396 (16%), Positives = 138/396 (34%), Gaps = 30/396 (7%) Query: 10 IVFLLFIVYMLNYMDRSALSITAPLIEKELGFN---AAEMGMIFSAFFIGYALFNFIGGW 66 ++ +L V L+ + + P + ++L + A G++ + + + + G Sbjct: 7 LIVILSTVA-LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 67 ASDKVGPKTVFLIAALLWSVFCGLTGLVTGLWTMLIVRVLFGMAEGPVSAAGNKIINNWI 126 SD+ G + V L++ +V + LW + I R++ G+ + AG I + Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGA-YIADIT 124 Query: 127 SRKESATAIGIFSAGSPLGGAVSGPIVGLLALSLGWRPAFGIIFLFGLVWVLLWYFIVSD 186 E A G SA G V+GP++G L F + L F++ + Sbjct: 125 DGDERARHFGFMSA-CFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 187 KPTMSKRLAPEERIDFENHEDVILSDDGRATPSLGYYMKQPMVWATTLAFFSYNYILFFF 246 +R E + + + FF + Sbjct: 184 SHKGERRPLRREAL-------------NPLASFRWARGMTVVAALMAV-FFIMQLVGQVP 229 Query: 247 LTWFPSYLNHSLHLDIKEISIATVIPWVIGAIGMVLGGVCSDVIYRITGNALLSRRLILG 306 + + H D I I+ G + + + + + L R L Sbjct: 230 AALWVIFGEDRFHWDATTIGISLA---AFGILHSLAQAMITGPVAA-----RLGERRALM 281 Query: 307 VCLAGAAVCVAVSGTVSTIGSAITLMSVSLFLLYLTGPIYWAVIQDVVHKDKVGSVGGAM 366 + + + + A +M V L + P A++ V +++ G + G++ Sbjct: 282 LGMIADGTGYILLAFATRGWMAFPIM-VLLASGGIGMPALQAMLSRQVDEERQGQLQGSL 340 Query: 367 HGLANISGIIGPLVTGFIVQFS-GKYDYAFYLAGAI 401 L +++ I+GPL+ I S ++ ++AGA Sbjct: 341 AALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAA 376 Score = 32.9 bits (75), Expect = 0.002 Identities = 31/121 (25%), Positives = 49/121 (40%), Gaps = 13/121 (10%) Query: 299 LSRRLILGVCLAGAAVCVAVSGTVST-----IGSAITLMSVSLFLLYLTGPIYWAVIQDV 353 RR +L V LAGAAV A+ T IG + ++ + TG + A I D+ Sbjct: 70 FGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA------TGAVAGAYIADI 123 Query: 354 VHKDKVGSVGGAMHGLANISGIIGPLVTGFIVQFSGKYDYAFYLAGAIAIVSSLLVFVFV 413 D+ G M + GP++ G + FS F+ A A+ ++ L + Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHA--PFFAAAALNGLNFLTGCFLL 181 Query: 414 K 414 Sbjct: 182 P 182
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 470 bits (1211), Expect = e-169 Identities = 235/386 (60%), Positives = 275/386 (71%), Gaps = 20/386 (5%) Query: 3 KVVVLSAVAAAVMMAGAANAAEIYNKDGNKLDLYGKVDGLHYFSSNHSTDGDQSYIRMGI 62 K VL+ V A++ AGAA+AAEIYNKDGNKLDLYGKVDGLHYFS + S DGDQ+Y+R+G Sbjct: 2 KRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVGF 61 Query: 63 KGETQITDQLTGFGQWEYQVNANRPEDGDSSGSPQSWTRLGFAGLAFADMGSVDYGRNYG 122 KGETQI DQLTG+GQWEY V AN E SWTRL FAGL F D GS DYGRNYG Sbjct: 62 KGETQINDQLTGYGQWEYNVQANTTE----GEGANSWTRLAFAGLKFGDYGSFDYGRNYG 117 Query: 123 VLYDIGSWTDVLPEFGNDSYEASDNFMTGRANGVLTYRNNDFFGLVDGLNIALQYQGKND 182 VLYD+ WTD+LPEFG DSY +DN+MTGRANGV TYRN DFFGLVDGLN ALQYQGKN+ Sbjct: 118 VLYDVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNE 177 Query: 183 GLSKEGDPLSNNAR---KSIAYQNGDGFGASATYDLGMGVSLGAAYTSSKRTLDQMTQDK 239 S + + N R I Y NGDGFG S TYD+GMG S GAAYT+S RT +Q+ Sbjct: 178 SQSADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGG 237 Query: 240 YD-NGDRAEAWTGGVKYDANNIYLAANYTRTYDMTYMGDTL----GGFAHKTDNWEMVGQ 294 GD+A+AWT G+KYDANNIYLA Y+ T +MT G T GG A+KT N+E+ Q Sbjct: 238 TIAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQ 297 Query: 295 YQFDNGLRPSLAFLQSRANDVD----GLGSFDLVKYIDVGSYYYFNKNMSAYVDYKINLL 350 YQFD GLRP+++FL S+ D+ DLVKY DVG+ YYFNKN S YVDYKINLL Sbjct: 298 YQFDFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLL 357 Query: 351 KDGNP----SNPNTDNTVALGLVYEF 372 D +P + +TD+ VALG+VY+F Sbjct: 358 DDDDPFYKDAGISTDDIVALGMVYQF 383
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 30.5 bits (69), Expect = 0.008 Identities = 12/51 (23%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 22 GQGKVADYIPALASVEGSKLGI-AICTVDGQHYQAGDAHERFSIQSISKVL 71 + + I S ++G+ + G+ A A ERF + S KV+ Sbjct: 21 ASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVV 71
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 56.8 bits (137), Expect = 5e-11 Identities = 44/192 (22%), Positives = 85/192 (44%), Gaps = 8/192 (4%) Query: 36 LSDIAESFHMQTAQVGIMLTIYAWVVAVMSLPFMLLTSQMERRKLLICLFVLFIASHVLS 95 L DIA F+ A + T + ++ + + L+ Q+ ++LL+ ++ V+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 96 FLAWN-FTVLVISRIGIAFAHAIFWSITASLAIRLAPAGKRAQALSLIATGTALAMVLGL 154 F+ + F++L+++R A F ++ + R P R +A LI + A+ +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 155 PIGRVVGQYFGWRTTFFAIGMGALITLLCLIKLLPKLPSEHSGSLKSLPLLFRRPALMSL 214 IG ++ Y W + I M +IT+ L+KLL K + LMS+ Sbjct: 157 AIGGMIAHYIHW-SYLLLIPMITIITVPFLMKLLKK------EVRIKGHFDIKGIILMSV 209 Query: 215 YVLTVVVVTAHY 226 ++ ++ T Y Sbjct: 210 GIVFFMLFTTSY 221
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 76.5 bits (188), Expect = 3e-17 Identities = 48/194 (24%), Positives = 84/194 (43%), Gaps = 3/194 (1%) Query: 8 LVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDR 67 L+WL LS L + + I D P A+ + + F+ F++ ++G LSD+ Sbjct: 16 LIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 68 YGRKPILLLGLSIFALGSLGMLWVESAAALLTL-RFVQAVGVCAATVIWQALVTDYYPSQ 126 G K +LL G+ I GS+ S +LL + RF+Q G A + +V Y P + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 127 KINRIFATIMPLVGLSPALAPLLGSWILTHFSWQAIFATLFVITLLLMLPALRLKPSVKA 186 + F I +V + + P +G I + W + L + ++ +P L + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIPMITIITVPFLMKLLKKEV 193 Query: 187 RTEGQDKLTFATLL 200 R +G + L+ Sbjct: 194 RIKGHFDIKGIILM 207
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 385 bits (991), Expect = e-136 Identities = 125/350 (35%), Positives = 202/350 (57%), Gaps = 4/350 (1%) Query: 2 SEKTEQPTEKKLRDGRKEGQVVKSIEITSLFQLIALYLYFHFFTEKMILILIASITFTLQ 61 EKTEQPT KK+RD RK+GQV KS E+ S ++AL ++ + + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAE 62 Query: 62 LVNKPFSYALTQLT-HALIESLTSALLFLGAGVIVATVGSVFLQVGVVIASKAIGFKSEH 120 PFS AL+ + + L+E L ++A + S +Q G +I+ +AI + Sbjct: 63 QSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMA-IASHVVQYGFLISGEAIKPDIKK 121 Query: 121 INPVSNFKQIFSLHSVVELCKSSLKVIMLSLIFAFFFYYYASTFRALPYCGLACGLLVVS 180 INP+ K+IFS+ S+VE KS LKV++LS++ T LP CG+ C ++ Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 181 SLIKWLWVGVMAFYIVVGILDYSFQYYKIRKDLKMSKDDVKQEHKDLEGDPQMKTRRREM 240 +++ L V ++V+ I DY+F+YY+ K+LKMSKD++K+E+K++EG P++K++RR+ Sbjct: 182 QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQF 241 Query: 241 QSEIQSGSLAQSVKQSVAVVRNPTHIAVCLGYHPTDMPIPRVLEKGSDAQANYIVNIAER 300 EIQS ++ ++VK+S VV NPTHIA+ + Y + P+P V K +DAQ + IAE Sbjct: 242 HQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEE 301 Query: 301 NCIPVVENVELARSLFFEVERGDKIPETLFEPVAALLRMVMK--IDYAHS 348 +P+++ + LAR+L+++ IP E A +LR + + I+ HS Sbjct: 302 EGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQHS 351
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 164 bits (418), Expect = 3e-52 Identities = 54/229 (23%), Positives = 100/229 (43%), Gaps = 5/229 (2%) Query: 8 WLIALAVAFIRPLSLSLLLPLLKSGSLGSALLRNGVLMSLTFPILPIIYQQKIMMHIGKD 67 WL +R L+L P+L S+ ++ G+ M +TF I P + + + Sbjct: 12 WLNLYFWPLLRVLALISTAPILSERSVPK-RVKLGLAMMITFAIAPSLPANDVPVF---S 67 Query: 68 YSWLGLVTGEVIIGFLIGFCAAVPFWAVDMAGFLLDTLRGATMGTIFNSTMEAETSLFGL 127 + L L +++IG +GF F AV AG ++ G + T + + Sbjct: 68 FFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLAR 127 Query: 128 LFSQFLCVIFFISGGMEFILNILYESYQYLPPGRTLLFDRQFLKYIQAEWRTLYQLCISF 187 + ++F G +++++L +++ LP G L FL +A ++ + Sbjct: 128 IMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSL-IFLNGLML 186 Query: 188 SVPAIICMVLADLALGLLNRSAQQLNVFFFSMPLKSILVLLTLLISFPY 236 ++P I ++ +LALGLLNR A QL++F PL + + + P Sbjct: 187 ALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPL 235
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 72.5 bits (178), Expect = 9e-21 Identities = 30/85 (35%), Positives = 50/85 (58%) Query: 4 SELTQFVTQLLWIVLFTSMPVVLVASVVGVIVSLVQALTQIQDQTLQFMIKLLAIAITLM 63 +L + L++VL S +VA+++G++V L Q +TQ+Q+QTL F IKLL + + L Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 VSYPWLSGILLNYTRQIMLRIGEHG 88 + W +LL+Y RQ++ G Sbjct: 62 LLSGWYGEVLLSYGRQVIFLALAKG 86
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 231 bits (592), Expect = 9e-80 Identities = 79/215 (36%), Positives = 130/215 (60%), Gaps = 8/215 (3%) Query: 8 LQLIGILFLLSILPLIIVMGTSFLKLAVVFSILRNALGIQQVPPNIALYGLALVLSLFIM 67 + LI +L ++LP II GT F+K ++VF ++RNALG+QQ+P N+ L G+AL+LS+F+M Sbjct: 5 ISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMFVM 64 Query: 68 GPTLLAVKERWHPVQVAGAPFWT-SEWDSKALAPYRQFLQKNSEEKEANYFRNLIKRTWP 126 P + + V + S+ + L YR +L K S+ + +F N + Sbjct: 65 WPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQY 124 Query: 127 ED-------IKRKIKPDSLLILIPAFTVSQLTQAFRIGLLIYLPFLAIDLLISNILLAMG 179 + K +I+ S+ L+PA+ +S++ AF+IG +YLPF+ +DL++S++LLA+G Sbjct: 125 GEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLALG 184 Query: 180 MMMVSPMTISLPFKLLIFLLAGGWDLTLAQLVQSF 214 MMM+SP+TIS P KL++F+ GW L L+ + Sbjct: 185 MMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 51.1 bits (122), Expect = 3e-10 Identities = 21/67 (31%), Positives = 38/67 (56%) Query: 247 LEQIPQQVLFEIGRASLEIGQLRQLKTGDVLPVGGCFAPEVTIRVNDRIIGQGELIACGN 306 + IP ++ E+GR + I +L +L G V+ + G + I +N +I QGE++ + Sbjct: 57 IMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVAD 116 Query: 307 EFMVRIT 313 ++ VRIT Sbjct: 117 KYGVRIT 123
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 52.3 bits (125), Expect = 5e-10 Identities = 28/170 (16%), Positives = 67/170 (39%), Gaps = 15/170 (8%) Query: 23 LYRSLPEDEANQMLALLMQHHIDAEKKQEEDGVTLRVEQSQFINAVELLRLNGYPHRQFT 82 L+ +L + + ++A L Q +I + V + L G P + Sbjct: 53 LFSNLSDQDGGAIVAQLTQMNIPYRFA--NGSGAIEVPADKVHELRLRLAQQGLP-KGGA 109 Query: 83 TADKMFPANQLVVSPQEEQQKINFLK--EQRIEGMLSQMEGVINAKVTIALPTYDEGS-- 138 ++ + +S EQ +N+ + E + + + V +A+V +A+P + S Sbjct: 110 VGFELLDQEKFGISQFSEQ--VNYQRALEGELARTIETLGPVKSARVHLAMP---KPSLF 164 Query: 139 --NASPSSVAVFIKYSPQVNMEAFRVK-IKDLIEMSIPGLQYSKISILMQ 185 S +V + P ++ ++ + L+ ++ GL ++++ Q Sbjct: 165 VREQKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQ 214
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 79.2 bits (195), Expect = 1e-21 Identities = 26/127 (20%), Positives = 49/127 (38%) Query: 16 LKQLLSVDPETVYASGYASWQEGDYSRAVIDFSWLVMAQPWSWRAHIALAGTWMMLKEYT 75 L ++ S E +Y+ + +Q G Y A F L + + R + L + +Y Sbjct: 28 LNEISSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYD 87 Query: 76 TAINFYGHALMLDASHPEPVYQTGVCLKMMGEPGLAREAFQTAIKMSYADASWSEIRQNA 135 AI+ Y + ++D P + CL GE A A ++ + E+ Sbjct: 88 LAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTEFKELSTRV 147 Query: 136 QIMVDTL 142 M++ + Sbjct: 148 SSMLEAI 154
>PF07132#Harpin protein (HrpN) Length = 356 Score = 29.3 bits (65), Expect = 0.011 Identities = 21/87 (24%), Positives = 35/87 (40%), Gaps = 2/87 (2%) Query: 95 GAMLSGVLTIGLGAVGGETGLIAGQAVGHTAGGVMGLGAGVAQRQSDQDKAIADLQQNGA 154 G+M+ G L GLG +G G + G +G GG +G G + + G Sbjct: 62 GSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSAL-GGGLGGALGAGM 120 Query: 155 QSYNKSLTEIMEKATEIMQQIIGVGSS 181 + N S + ++ ++G G S Sbjct: 121 NAMNPS-AMMGSLLFSALEDLLGGGMS 146
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 89.6 bits (222), Expect = 2e-25 Identities = 40/154 (25%), Positives = 66/154 (42%), Gaps = 7/154 (4%) Query: 6 TLQQAHDTMRFFRRGGSLRMLL---DDDVTQPLNTLYRYAMQLMDVKEFAGAARLFQLLT 62 T + F + GG++ ML D L LY A ++ A ++FQ L Sbjct: 8 TQEYQLAMESFLKGGGTIAMLNEISSDT----LEQLYSLAFNQYQSGKYEDAHKVFQALC 63 Query: 63 IYDAWSFDYWFRLGECCQAQKHWGEAIYAYGRAAQIKIDAPQAPWAAAECYLACDNVCYA 122 + D + ++ LG C QA + AI++Y A + I P+ P+ AAEC L + A Sbjct: 64 VLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEA 123 Query: 123 IKALKAVVRICGEVSEHQILRLRAEKMLQQLSDR 156 L + + +E + L R ML+ + + Sbjct: 124 ESGLFLAQELIADKTEFKELSTRVSSMLEAIKLK 157
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 581 bits (1500), Expect = 0.0 Identities = 158/500 (31%), Positives = 261/500 (52%), Gaps = 15/500 (3%) Query: 11 LLFILNTAKSDELSWKGNDFTLYARQMPLAEVLHLLSENYDTAITISPLITATFSGKIPP 70 LL + + + + EL W + A+ L ++L NYD + +S I SG+ Sbjct: 17 LLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKINDKVSGQFEH 76 Query: 71 GPPVDILNNLAAQYDLLTWFDGSMLYVYPASLLKHQVITFNILSTGRFIHYLRSQNILSS 130 P D L ++A+ Y+L+ ++DG++LY++ S + ++I L+ I Sbjct: 77 DNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQALQRSGIWE- 135 Query: 131 PGCEVKEITGTRAVEVSGVPSCLTRISQLASVLDNALIKR--KDSAVSVSIYTLKYATAM 188 P + R V VSG P L + Q A+ L+ R K A+++ I+ LKYA+A Sbjct: 136 PRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEIFPLKYASAS 195 Query: 189 DTQYQYRDQSVVVPGVVSVL-REMSKTSVPASSTNN-----GSPATQALPMFAADPRQNA 242 D YRD V PGV ++L R +S ++ + +N + A ADP NA Sbjct: 196 DRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQARVEADPSLNA 255 Query: 243 VIVRDYAANMAGYRKLITELDQRQQMIEISVKIIDVNAGDINQLGIDWGTAVSLGG---- 298 +IVRD M Y++LI LD+ IE+++ I+D+NA + +LG+DW + G Sbjct: 256 IIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQV 315 Query: 299 --KKIAFNTGLNDGGASGFSTVISDTSNFMVRLNALEKSSQAYVLSQPSVVTLNNIQAVL 356 K + + GA G + R+N LE A V+S+P+++T N QAV+ Sbjct: 316 VIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVI 375 Query: 357 DKNITFYTKLQGEKVAKLESITTGSLLRVTPRLLNDNGTQKIMLNLNIQDGQQSDTQSET 416 D + T+Y K+ G++VA+L+ IT G++LR+TPR+L +I LNL+I+DG Q S Sbjct: 376 DHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGI 435 Query: 417 DSLPEVQNSEIASQATLLAGQSLLLGGFKQGKQIHSQNKIPLLGDIPVVGHLFRNDTTQV 476 + +P + + + + A + GQSL++GG + + + +K+PLLGDIP +G LFR + Sbjct: 436 EGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELT 495 Query: 477 HSVIRLFLIKASVVNNGISH 496 +RLF+I+ +++ GI+H Sbjct: 496 RRTVRLFIIEPRIIDEGIAH 515
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 6e-14 Identities = 31/156 (19%), Positives = 57/156 (36%), Gaps = 13/156 (8%) Query: 691 ILLVDDADINRDIIGKMLVSLGQHVTIAASSNEALTLSQQQRFDLVLIDIRMPEIDGIEC 750 IL+ DD R ++ + L G V I +++ DLV+ D+ MP+ + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 751 VQLWHDEPNNLDPDCMFVALSASVATEDIHRCKKNGIHHYITKPVTLATLARYISIAAEY 810 + PD + +SA + + G + Y+ KP L L Sbjct: 66 LP----RIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIG-------- 113 Query: 811 QLLRNIELQEQDPSRCSALLAT-DDMVINSKIFQSL 845 + R + ++ PS+ +V S Q + Sbjct: 114 IIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEI 149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.0 bits (161), Expect = 6e-15 Identities = 28/119 (23%), Positives = 50/119 (42%), Gaps = 2/119 (1%) Query: 1 MKEYKILLVDDHEIIINGIMNALLPWPHFKIVEHVKNGLEVYNACCAYEPDILILDLSLP 60 M IL+ DD I + AL + V N ++ A + D+++ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GINGLDIIPQLHQRWPAMNILVYTAYQQEYMTIKTLAAGANGYVLKSSSQQVLLAALQT 119 N D++P++ + P + +LV +A IK GA Y+ K L+ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.5 bits (209), Expect = 2e-21 Identities = 31/127 (24%), Positives = 56/127 (44%) Query: 2 ATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDGQ 61 ATI + DDD A+ L GYDV+ + A + +V+ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 GVHDALRQCGSTLAVVFLTGHGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVSS 121 + +++ L V+ ++ A++ ++GA D+L KP + L + RAL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 AAVARRE 128 ++ E Sbjct: 124 RRPSKLE 130
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.015 Identities = 23/103 (22%), Positives = 43/103 (41%), Gaps = 3/103 (2%) Query: 8 TAVGLYFNYFVHGMGVILMSLNMSSLEQQWHTSAAGVSIVISSLGIGRLSVLLIA---GM 64 + + + +G+ L+ + L + S + L + L A G Sbjct: 6 PLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGA 65 Query: 65 LSDRFGRRPFIILGTACYLIFFIGILYAQTIFVAYACGFLAGM 107 LSDRFGRRP +++ A + + + A ++V Y +AG+ Sbjct: 66 LSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI 108
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.5 bits (79), Expect = 8e-04 Identities = 32/166 (19%), Positives = 71/166 (42%), Gaps = 7/166 (4%) Query: 23 FLHGMSVITLAQNMTSLAQKFSTDSAGIAYLISGIGLGRLVSILFFGVLSDKFGRRAIIL 82 F ++ + L ++ +A F+ A ++ + L + +G LSD+ G + ++L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 83 LGAVLYML----FFFGIPASPNLMIAFILAVCVGVANSALDTGGYPALMECFPKASGSAV 138 G ++ F G L++A + A AL + G A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY--IPKENRGKAF 141 Query: 139 ILVKAMVSFGQMIYPLIVSALLVNHIWYGYAVVIPGILFVLITLML 184 L+ ++V+ G+ + P I ++ ++I + Y ++IP I + + ++ Sbjct: 142 GLIGSIVAMGEGVGPAI-GGMIAHYIHWSYLLLIPMITIITVPFLM 186
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.015 Identities = 10/22 (45%), Positives = 13/22 (59%) Query: 28 ILHLVGPNGAGKSTLLARMAGL 49 + L G G GKSTL+ + GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>PF03944#delta endotoxin Length = 633 Score = 28.9 bits (64), Expect = 0.011 Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 72 TQAYTGRPWPLIDGVGQIYGMYVITGLKTTR 102 TQ++T + WP + + Q+ YV+ G R Sbjct: 285 TQSFTSQDWPFLYSLFQVNSNYVLNGFSGAR 315
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 33.9 bits (77), Expect = 0.004 Identities = 34/267 (12%), Positives = 69/267 (25%), Gaps = 39/267 (14%) Query: 5 DIRVSFSAIDKLTRPVETARQSVGSLADSLKKTQADIKSLGTQSRAFSR----LRENFTR 60 + I L L +L+ + + + L Sbjct: 170 FSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKAD 229 Query: 61 TTEKIQKTQRTLNGLRQSQQAGNAMTDKQREHIAQLAAKLDRLNEVRTREKEKLREASRE 120 + ++ + A A+L L+ T + K++ E Sbjct: 230 LEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 289 Query: 121 MVRHGITLSGSDRTIQSAIRRTEQYTHTLDAERQMLAR-VTKARAQYDRMQQVAGRLRGG 179 + + Q L+A RQ L R + +R +++ +L Sbjct: 290 KAALEAEKADLEHQSQV-----------LNANRQSLRRDLDASREAKKQLEAEHQKL--- 335 Query: 180 GAVALGAATAAGYGAGQFLAPAVSFDREVSRVGALTRLDKSDPQFAALREQAKKLGAETQ 239 + A SR LD S L + +KL + + Sbjct: 336 -EEQNKISEA-------------------SRQSLRRDLDASREAKKQLEAEHQKLEEQNK 375 Query: 240 FTSRDAASGQAFLAMAGFTPQAIQAAL 266 + S + L + + ++ AL Sbjct: 376 ISEASRQSLRRDLDASREAKKQVEKAL 402
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 36.7 bits (85), Expect = 1e-07 Identities = 15/47 (31%), Positives = 26/47 (55%), Gaps = 2/47 (4%) Query: 1 MSQKPLKTA--IICITAVLIIWMLHGSLCELRMRLGGAEFAAFLQCK 45 + + L I+C+T ++ ++ SLCE+R R G E AAF+ + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYE 49
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 38.7 bits (90), Expect = 2e-08 Identities = 14/47 (29%), Positives = 27/47 (57%), Gaps = 2/47 (4%) Query: 1 MSQKSL--STIAICIAVVLIIWMLRGSLCELHMRLGGAEFAAFLQCK 45 + + SL + +C+ +++ ++ R SLCE+ R G E AAF+ + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYE 49
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (299), Expect = 6e-39 Identities = 34/89 (38%), Positives = 55/89 (61%) Query: 4 TKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQVKLSGFGNFDLRDKNQRPGR 63 K ++ + + L+K+D+ V+ F + L GE+V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPKTGEDIPITARRVVTFRPGQKLKSRVE 92 NP+TGE+I I A +V F+ G+ LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.012 Identities = 17/59 (28%), Positives = 25/59 (42%) Query: 49 QGLTVGIIILTIGVMAPIASGTLPPSTLIHSFVNWKSLVAIAVGVFVSWLGGRGITLMG 107 Q + L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDG 232
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.002 Identities = 8/37 (21%), Positives = 17/37 (45%), Gaps = 5/37 (13%) Query: 4 LSWIIFGLIAGILAKWIMPG-----KDGGGFFMTIIL 35 + I+ G I+G++ W+ K ++ I+L Sbjct: 163 AAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILL 199
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 27.0 bits (60), Expect = 0.047 Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 5/61 (8%) Query: 77 PHWQHVAAKLMHIALYFTFLALPLLGVAMMASGGKSWSFFGFTVPVFLTPDSTLKSDIKR 136 P Q ++ + ++ L F +L PLL VA + + +GF ++ ++ +K DIK+ Sbjct: 67 PFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFL----ISGEA-IKPDIKK 121 Query: 137 I 137 I Sbjct: 122 I 122
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 190 bits (485), Expect = 9e-65 Identities = 66/187 (35%), Positives = 92/187 (49%), Gaps = 18/187 (9%) Query: 1 MKNIILSTLVITTGVLVVNVAQADTNAFSVGYAQSKVQDFKN-IRGVNVKYRYE-DDSPV 58 MK I + + + A T+ + GYAQS Q N + G N+KYRYE D+SP+ Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKMGGFNLKYRYEEDNSPL 60 Query: 59 SFISSLSYLYGDSQASGSVESEGIHYHDKFEVKYGSFMVGPAYRLSDNFSLYALAGVGTV 118 I S +Y AS D + +Y GPAYR++D S+Y + GVG Sbjct: 61 GVIGSFTYTEKSRTASSG---------DYNKNQYYGITAGPAYRINDWASIYGVVGVGYG 111 Query: 119 KATFKEHSTQDGDSFSNKISSRKTGFAWGAGVQMNPLENIVVDVGYEGSNISSTKINGFN 178 K E+ T D+ GF++GAG+Q NP+EN+ +D YE S I S + + Sbjct: 112 KFQTTEYPTYKHDT-------SDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWI 164 Query: 179 VGVGYRF 185 GVGYRF Sbjct: 165 AGVGYRF 171
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 294 bits (755), Expect = e-103 Identities = 125/276 (45%), Positives = 165/276 (59%), Gaps = 16/276 (5%) Query: 1 MKKPVFFLLTMIICSYISFACANISDYKVMTWNLQGSSASTESKWNVNVRQLLSGTAGVD 60 MKK + L+ + S+ + A +++D++V TWNLQG+SA+TESKWN+NVRQL+SG VD Sbjct: 1 MKKYIISLI--VFLSFYAQA--DLTDFRVATWNLQGASATTESKWNINVRQLISGENAVD 56 Query: 61 ILMVQEAGAVPTSAVPTGRHIQPFGVGIPIDEYTWNLGTTSRQDIRYIYHSAIDVGARRV 120 IL VQEAG+ P++AV TG I GIP+ E WNL T SR YIY SA+D RV Sbjct: 57 ILAVQEAGSPPSTAVDTGTLIP--SPGIPVRELIWNLSTNSRPQQVYIYFSAVDALGGRV 114 Query: 121 NLAIVSRQRADNVYVLRPTTVASRPVIGIGLGNDVFLTAHALASGGPDAAAIVRVTINFF 180 NLA+VS +RAD V+VL P RP++GI +GND F TAHA+A DA A+V NFF Sbjct: 115 NLALVSNRRADEVFVLSPVRQGGRPLLGIRIGNDAFFTAHAIAMRNNDAPALVEEVYNFF 174 Query: 181 RQ---PQMRHLSWFLAGDFNRSPDRLENDLMTEHLERVVAVLAPTEPTQIGGGILDYGVI 237 R P + L+W + GDFNR P LE +L T + R +++P TQ LDY V Sbjct: 175 RDSRDPVHQALNWMILGDFNREPADLEMNL-TVPVRRASEIISPAAATQTSQRTLDYAVA 233 Query: 238 VDRAPYSQR------VEALRNPQLASDHYPVAFLAR 267 + + V R Q++SDH+PV R Sbjct: 234 GNSVAFRPSPLQAGIVYGARRTQISSDHFPVGVSRR 269
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 80.2 bits (197), Expect = 4e-20 Identities = 56/170 (32%), Positives = 85/170 (50%), Gaps = 12/170 (7%) Query: 22 VYRVDSTPPDVIFRDGFSLLGYNRNFQQFISGRSCSGGSSDSRYIATTSSVNQT------ 75 VYR DS PP+ +F++GF+ G N N ++GRSC GSS+S +++T+SS T Sbjct: 41 VYRYDSRPPEDVFQNGFTAWGNNDNVLDHLTGRSCQVGSSNSAFVSTSSSRRYTEVYLEH 100 Query: 76 ---YAIARAYYSRSTFKGNLYRYQIRADNNFYSLLPS-ITYLETQGGHFN-AYEKTMMRL 130 A+ R T Y Y++RADNNFY S Y++T G + + Sbjct: 101 RMQEAVEAERAGRGTGHFIGYIYEVRADNNFYGAASSYFEYVDTYGDNAGRILAGALATY 160 Query: 131 QREYVSTLSILPENIQKAVALVYDSATGLVKDGVSTMNSSYLGLSTTSNP 180 Q EY++ I PENI++ + ++ TG N+ Y+ T +NP Sbjct: 161 QSEYLAHRRIPPENIRRVTRVYHNGITGETTT-TEYSNARYVSQQTRANP 209
>BORPETOXINB#Bordetella pertussis toxin B subunit signature. Length = 226 Score = 31.9 bits (72), Expect = 4e-04 Identities = 29/101 (28%), Positives = 41/101 (40%), Gaps = 7/101 (6%) Query: 30 TNAYYSDEVISEIHVGQIDTSPYFCIKTVKANGSGTPVV-ACAVSKQSIWAPSFKELLDQ 88 T+ YYS+ + + T+ C V+ SG PV+ AC + + L Sbjct: 126 TDHYYSNVTATRLLS---STNSRLCAVFVR---SGQPVIGACTSPYDGKYWSMYSRLRKM 179 Query: 89 ARYFYSTGQSVRIHVQKNIWTYPLFVNAFSANALVGLSSCS 129 Y G SVR+HV K Y F AL G+S C+ Sbjct: 180 LYLIYVAGISVRVHVSKEEQYYDYEDATFETYALTGISICN 220
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 54.7 bits (131), Expect = 2e-09 Identities = 49/259 (18%), Positives = 92/259 (35%), Gaps = 26/259 (10%) Query: 513 PSEEEYAERKRPEQPALATFAMPDVPPAPTPVEPAVSVATAKKDNVAAAQPAQPGLFSRF 572 P E+ + DVP P+ + A+ D PA P S Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSN-----NEEIARVDEAPVPPPA-PATPSET 1036 Query: 573 LNALKQLFSGEETKTVETAAPKAEEKAERQQDRRKPRQNNRRDRNERRDTRDNRAGRDGG 632 S +E+KTVE A E + ++ K ++N + +T+ N + G Sbjct: 1037 TE-TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKA-----NTQTNEVAQSGS 1090 Query: 633 ESRDDNRRNRRQAQQQNAEAR---DTRQQETAEKVKTGDEQQQTPRRERSRRRNDDKRQA 689 E+++ ++ E + +T + + KV + Q +P++E+S A Sbjct: 1091 ETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTS----QVSPKQEQSETVQPQAEPA 1146 Query: 690 QQEVKALNREELPVQETEQEERVQQVQPRRKQRQLNQKVRFTNSAVVETVDTPVVVDEPR 749 ++ +N +E Q + QP ++ N + T S V T ++ V E Sbjct: 1147 RENDPTVNIKEPQSQTNTTAD---TEQPAKETSS-NVEQPVTESTTVNTGNSVVENPENT 1202 Query: 750 PVENVEQPVPAPRTELAKV 768 + P +E + Sbjct: 1203 TPATTQ---PTVNSESSNK 1218 Score = 39.3 bits (91), Expect = 1e-04 Identities = 51/372 (13%), Positives = 88/372 (23%), Gaps = 47/372 (12%) Query: 630 DGGESRDDNRRNRRQAQQQNAEARDTRQQETAEKVKTGDEQQQTPRRERSRRRNDDKRQA 689 D G + R + N E Q + T + Q S + Sbjct: 963 DLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDE 1022 Query: 690 QQEVKALNREELPVQETEQEERVQQVQPRRKQRQLNQKVRFTNSAVVETVDTPVVVDEPR 749 ET E Q+ + K Q + N V + V + Sbjct: 1023 APVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKE-AKSNVKANTQ 1081 Query: 750 PVENVEQPVPAPRTELAKVDLPVVADIAPEQDDSVEPRDNTGMPRRSRRSPRHLRVSGQR 809 E + T+ + A + E+ VE +++ P+ + Sbjct: 1082 TNEVAQSGSETKETQTTETKET--ATVEKEEKAKVETE-------KTQEVPKVTSQVSPK 1132 Query: 810 RRRYRDERYPTQSPMPLTVACASPEMASGKVWIRYPIVRPQETQVVEEQREADLALPQPV 869 + + + + P V +E Q + AD P Sbjct: 1133 QEQSETVQPQAEPARE-----------------NDPTVNIKEPQS-QTNTTADTEQPAKE 1174 Query: 870 VAEPQVIAATVALEPQASVQAVENVAVEPQTVAEPQAPEVVEVETTHPEVIAAPVDEQPQ 929 Q V + + PE TT P V + ++ Sbjct: 1175 T-------------SSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKN 1221 Query: 930 LIAESDTPEAQEVIA------DAEPVAETADASITVAENVADVVVVEPEEETKAEAAVVE 983 S V D VA S ++D AV + Sbjct: 1222 RHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQ 1281 Query: 984 HTAEETVIATAQ 995 H ++ + Q Sbjct: 1282 HISQLEMNNEGQ 1293
>FLAGELLIN#Flagellin signature. Length = 507 Score = 41.2 bits (96), Expect = 4e-06 Identities = 30/138 (21%), Positives = 59/138 (42%) Query: 1 MRISTQMMYEQNMSGITNSQAEWMKLGEQMSTGKRVTNPSDDPIAASQAVVLSQAQAQNS 60 I+T + + + SQ+ E++S+G R+ + DD + A + + Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 QYALARTFATQKVSLEESVLSQVTTAIQTAQEKIVYAGNGTLSDDDRASLATDLQGIRDQ 120 Q + E L+++ +Q +E V A NGT SD D S+ ++Q ++ Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 LMNLANSTDGNGRYIFAG 138 + ++N T NG + + Sbjct: 122 IDRVSNQTQFNGVKVLSQ 139
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 664 bits (1714), Expect = 0.0 Identities = 438/553 (79%), Positives = 487/553 (88%), Gaps = 8/553 (1%) Query: 2 SSLINHAMSGLNAAQAALNTVSNNINNYNVAGYTRQTTILAQANSTLGAGGWIGNGVYVS 61 SSLIN+AMSGLNAAQAALNT SNNI++YNVAGYTRQTTI+AQANSTLGAGGW+GNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRGAQNQSSGLTTRYEQMSKIDNLLADKSSSLSGSLQSFFTSLQTLV 121 GVQREYDAFITNQLR AQ QSSGLT RYEQMSKIDN+L+ +SSL+ +Q FFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKAEGLVNQFKTTDQYLRDQDKQVNIAIGSSVAQINNYAKQIANLND 181 SNAEDPAARQALIGK+EGLVNQFKTTDQYLRDQDKQVNIAIG+SV QINNYAKQIA+LND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRMTGVGAGASPNDLLDQRDQLVSELNKIVGVEVSVQDGGTYNLTMANGYTLVQGSTA 241 QISR+TGVGAGASPN+LLDQRDQLVSELN+IVGVEVSVQDGGTYN+TMANGY+LVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPTRTTVAYVDEAAGNIEIPEKLLNTGSLGGLLTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADP+RTTVAYVD AGNIEIPEKLLNTGSLGG+LTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFADAFNAQHTKGYDADGNKGKDFFSIGSPVVYSNSNNADKTVSLTAKVVDSTKVQAT 361 ALAFA+AFN QH G+DA+G+ G+DFF+IG P V N+ N V++ A V D++ V AT Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGD-VAIGATVTDASAVLAT 359 Query: 362 DYKIVFDGTDWQVTRTADNTTFTATKDADGKLEIDGLKVTVGTGAQKNDSFLLKPVSNAI 421 DYKI FD WQVTR A NTTFT T DA+GK+ DGL++T NDSF LKPVS+AI Sbjct: 360 DYKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAI 419 Query: 422 VDMNVKVTNEAEIAMASESKLDPDVDTGDSDNRNGQALLDLQ-NSNVVGGNKTFNDAYAT 480 V+M+V +T+EA+IAMASE D GDSDNRNGQALLDLQ NS VGG K+FNDAYA+ Sbjct: 420 VNMDVLITDEAKIAMASEE------DAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYAS 473 Query: 481 LVSDVGNKTSTLKTSSTTQANVVKQLYKQQQSVSGVNLDEEYGNLQRYQQYYLANAQVLQ 540 LVSD+GNKT+TLKTSS TQ NVV QL QQQS+SGVNLDEEYGNLQR+QQYYLANAQVLQ Sbjct: 474 LVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQ 533 Query: 541 TANALFDALLNIR 553 TANA+FDAL+NIR Sbjct: 534 TANAIFDALINIR 546
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 499 bits (1285), Expect = 0.0 Identities = 263/316 (83%), Positives = 289/316 (91%), Gaps = 3/316 (0%) Query: 1 MIGDGKLLASAAWDAQSLNELKAKAGQDPAANIRPVARQVEGMFVQMMLKSMREALPKDG 60 MI D KLLASAAWDAQSLNELKAKAG+DPAANIRPVARQVEGMFVQMMLKSMR+ALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSDQTRLYTSMYDQQIAQQMTAGKGLGLADMMVKQMTGGQTMPADDAPQVPLKFSLET 120 LFSS+ TRLYTSMYDQQIAQQMTAGKGLGLA+MMVKQMT Q +P + P P+KF LET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VNSYQNQALTQLVRKAIPKTPDSSDAPLSGDSKDFLARLSLPARLASEQSGVPHHLILAQ 180 V YQNQAL+QLV+KA+P+ D S L GDSK FLA+LSLPA+LAS+QSGVPHHLILAQ Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDS---LPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQ 177 Query: 181 AALESGWGQRQILRENGEPSYNVFGVKATASWKGPVTEITTTEYENGEAKKVKAKFRVYS 240 AALESGWGQRQI RENGEPSYN+FGVKA+ +WKGPVTEITTTEYENGEAKKVKAKFRVYS Sbjct: 178 AALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYS 237 Query: 241 SYLEALSDYVALLTRNPRYAAVTTAATAEQGAVALQNAGYATDPNYARKLTSMIQQLKAM 300 SYLEALSDYV LLTRNPRYAAVTTAA+AEQGA ALQ+AGYATDP+YARKLT+MIQQ+K++ Sbjct: 238 SYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSI 297 Query: 301 SEKVSKTYSANLDNLF 316 S+KVSKTYS N+DNLF Sbjct: 298 SDKVSKTYSMNIDNLF 313
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 429 bits (1104), Expect = e-153 Identities = 153/362 (42%), Positives = 215/362 (59%), Gaps = 9/362 (2%) Query: 5 LAGIVLALVTTLAHAERIRDLTSVQGVRENSLIGYGLVVGLDGTGDQTTQTPFTTQTLNN 64 A L+ A RI+D+ S+Q R+N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 14 SALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMRA 73 Query: 65 MLSQLGITVPTGTNMQLKNVAAVMVTASYPPFARQGQTIDVVVSSMGNAKSLRGGTLLMT 124 ML LGIT G + KN+AAVMVTA+ PPFA G +DV VSS+G+A SLRGG L+MT Sbjct: 74 MLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIMT 132 Query: 125 PLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAIIERELPTQFGAGNT 184 L G D Q+YA+AQG ++V G A +++ R+ NGAIIERELP++F Sbjct: 133 SLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSVN 192 Query: 185 INLQLNDEDFTMAQQITDAINRAR----GYGSATALDARTVQVRVPSGNSSQVRFLADIQ 240 + LQL + DF+ A ++ D +N G A D++ + V+ P + R +A+I+ Sbjct: 193 LVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEIE 251 Query: 241 NMEVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQLNVNQPNTPFGGG 300 N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF G Sbjct: 252 NLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSRG 309 Query: 301 QTVVTPQTQIDLRQSGGSLQSVRSSANLNSVVRALNALGATPMDLMSILQSMQSAGCLRA 360 QT V PQT I Q G + ++ +L ++V LN++G +++ILQ ++SAG L+A Sbjct: 310 QTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQA 368 Query: 361 KL 362 +L Sbjct: 369 EL 370
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 353 bits (908), Expect = e-127 Identities = 211/232 (90%), Positives = 223/232 (96%) Query: 1 MQKYALHAYPVMALMVATLTGCAWIPAKPLVQGATTAQPIPGPVPVANGSIFQSAQPINY 60 MQK A H Y + +L+V +LTGCAWIP+ PLVQGAT+AQP+PGP PVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTSFGFDTVPRYLQGLFGNS 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKT+FGFDTVPRYLQGLFGN+ Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADMEASGGNSFNGKGGANASNTFSGTLTVTVDQVLANGNLHVVGEKQIAINQGTEFIRF 180 RAD+EASGGN+FNGKGGANASNTFSGTLTVTVDQVL NGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNSVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSN+VPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.6 bits (121), Expect = 5e-09 Identities = 53/253 (20%), Positives = 92/253 (36%), Gaps = 24/253 (9%) Query: 56 AFLATAAFIGRPFGGALFGLLADKFGRKPLMMWSIVAYSVGTGLSGLASGVIMLTLSRFI 115 A A F P GAL +D+FGR+P+++ S+ +V + A + +L + R + Sbjct: 50 ALYALMQFACAPVLGAL----SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 116 VGMGMAGEYACASTYAVESWPKHLKSKASAFLVSGFGIGNIIAAYFMPSFAEAYGWRAAF 175 G+ A + A + +++ F+ + FG G ++A + + A F Sbjct: 106 AGITGATGAVAGAYIA-DITDGDERARHFGFMSACFGFG-MVAGPVLGGLMGGFSPHAPF 163 Query: 176 FV-GLLPVLLVIYIRARAPESKEWEE--AKLSGLGKHSQSAWSVFSLSMKGLFNRA---- 228 F L L + PES + E + L + W+ + L Sbjct: 164 FAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQ 223 Query: 229 ---QFPLTLCVFIVLFSIFGANWPIFGLLPTYLAGEGFDTGVVSNLMTAAAFGTVLGN-- 283 Q P L V+F +W + LA G ++ M LG Sbjct: 224 LVGQVPAAL---WVIFGEDRFHWDA-TTIGISLAAFGI-LHSLAQAMITGPVAARLGERR 278 Query: 284 -IVWGLCADRIGL 295 ++ G+ AD G Sbjct: 279 ALMLGMIADGTGY 291
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.3 bits (151), Expect = 4e-14 Identities = 30/158 (18%), Positives = 58/158 (36%), Gaps = 8/158 (5%) Query: 20 RQLILTAALAVFSQYGIHGARLEQVAERAGVSKTNLLYYYPSKEALYVAVMRQILDVWLA 79 RQ IL AL +FSQ G+ L ++A+ AGV++ + +++ K L+ + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 80 PLKAFRAEF--SPLEAIKEYIRLKLEVSRDYPQASRLF-CMEMLAGAPLLMEELTGDLKA 136 ++A+F PL ++E + LE + + L + M + + Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132 Query: 137 LIDEKSALIAGWVHSG-----KLAPVSPHHLIFMIWAA 169 L E I + A + ++ Sbjct: 133 LCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY 170
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 2e-20 Identities = 30/117 (25%), Positives = 56/117 (47%), Gaps = 1/117 (0%) Query: 2 KILLIEDNQKTIEWVRQGLTEAGYVVDYACDGRDGLHLALQEHYSLIILDIMLPGLDGWQ 61 IL+ +D+ + Q L+ AGY V + L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRALRTAHQS-PVICLTARDSVEDRVKGLEAGANDYLVKPFSFAELLARVRAQLRQ 117 +L ++ A PV+ ++A+++ +K E GA DYL KPF EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 18/102 (17%), Positives = 38/102 (37%), Gaps = 15/102 (14%) Query: 348 ILLQRVLSNLLTNAIRYSDENAVIRIESAYDDNVAEIRVANPGSHPADADKLFRRFWRGD 407 +L+Q ++ N + + I + I ++ D+ + V N GS K Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE-------- 309 Query: 408 NARHTAGFGLGLSLVNA-IALLHGGSASYRYADEHNIFSVRL 448 G GL V + +L+G A + +++ + + Sbjct: 310 ------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 656 bits (1693), Expect = 0.0 Identities = 187/396 (47%), Positives = 254/396 (64%), Gaps = 5/396 (1%) Query: 166 LNNQPWQTIKNTLTHNGHHYTNTQLPAAEMKIGAKDIFPSAYQGKGVCSWDTRNIHHANN 225 LNN+ W + ++H+G +Y PA+ MKIG K+IF Y GKG+C TR H N Sbjct: 146 LNNKNWGPVNKNISHHGKNYGFQLTPASHMKIGNKNIFVKEYNGKGICCASTRESDHIAN 205 Query: 226 LWMSTVSVHEDGKDKTLFCGIRHGVLSPYH-EKDPLLRQVGAENKAKEVLTAALFSKPEL 284 +W+S V V ++GK+ +F GIRHGV+S Y +K+ R V A NKA+E+++AAL+S+PEL Sbjct: 206 MWLSKV-VDDEGKE--IFSGIRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPEL 262 Query: 285 LNRALEGEAVSLKLVSVGLLTASNIFGKEGTMVEDQMRAWQSL-TQPGKMIHLKIRNKDG 343 L++AL G+ V LK+VS LLT +++ G E +M++DQ+ A + L ++ G+ L IRN DG Sbjct: 263 LSQALSGKTVDLKIVSTSLLTPTSLTGGEESMLKDQVNALKGLNSKRGEPTKLLIRNSDG 322 Query: 344 DLQTVKIKPDVAAFNVGVNELALKLGFGLKASDRYNAEALHQLLGNDLRPEARPGGWVGE 403 L+ V + V FN GVNELALK+G G + D+ N E++ LLG++ GGW E Sbjct: 323 LLKEVSVNLKVVTFNFGVNELALKMGLGWRNVDKLNDESICSLLGDNFLKNGVIGGWAAE 382 Query: 404 WLAQYPDNYEVVNTLARQIKDIWKNNLHHKDGGEPYKLAQRLAMLAHEIDAVPAWNCKSG 463 + + P V LA QIK+I L D GEPYKL+QR+ +LA+ I AVP WNCKSG Sbjct: 383 AIEKNPPCKNDVIYLANQIKEIINKKLQKNDNGEPYKLSQRMTLLAYTIGAVPCWNCKSG 442 Query: 464 KDRTGMMDSEIKREHISLHQTHMLSAPGSLPDSGGQKIFQKVLLNSGNLEIQKQNTGGAG 523 KDRTGM D+EIKRE I H+T S S S +++F +L+NSGN+EIQ+ NTG G Sbjct: 443 KDRTGMQDAEIKREIIRKHETGQFSQLNSKLSSEEKRLFSTILMNSGNMEIQEMNTGVPG 502 Query: 524 NKVMKNLSPEVLNLSYQKRVGDENIWQSVKGISSLI 559 NKVMK L L LSY +R+GD IW VKG SS + Sbjct: 503 NKVMKKLPLSSLELSYSERIGDSKIWNMVKGYSSFV 538
>PF07824#Type III secretion chaperone Length = 120 Score = 165 bits (419), Expect = 1e-56 Identities = 33/114 (28%), Positives = 63/114 (55%), Gaps = 1/114 (0%) Query: 1 MESLLNRLYDALGLDAPE-DEPLLIIDDGIQVYFNESDHTLEMCCPFMPLPDDILTLQHF 59 ME L + + ALG+ + + D+ +++DD + +Y + ++ + CPF LP++I L + Sbjct: 1 MEDLADVICRALGIPSIDTDDQAIMLDDDVLIYIEKEGDSINLLCPFCALPENINDLIYA 60 Query: 60 LRLNYTSAVTIGADADNTALVALYRLPQTSTEEEALTGFELFISNVKQLKEHYA 113 L LNY+ + + D + +L+A L + E+ E +IS V+ LK+ +A Sbjct: 61 LSLNYSEKICLATDDEGGSLIARLDLTGINEFEDIYVNTEYYISRVRWLKDEFA 114
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.5 bits (79), Expect = 7e-04 Identities = 39/158 (24%), Positives = 62/158 (39%), Gaps = 6/158 (3%) Query: 8 VMLLLCGLLLLT-LAIAVLNTLVPLWLAQANLPTWQVGMVSSSYFTGNLVGTLFTGYLIK 66 +++ LC L + L VLN +P N P V++++ +GT G L Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 67 RIGFNRSYYLASLIFAAGCVGLGVMVGFWSWMSW-RFIAGIGCAMIWVVVESALMCSGTS 125 ++G R +I G V V F+S + RFI G G A +V + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 126 HNRGRLLAAYMMVYYMGTFLGQLLVSKVSGELLHVLPW 163 NRG+ + MG +G + G + H + W Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPA----IGGMIAHYIHW 168
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.2 bits (133), Expect = 2e-10 Identities = 30/125 (24%), Positives = 49/125 (39%), Gaps = 17/125 (13%) Query: 4 RILVLGASGYIGQHLVFALSQQGHQVRA---------AARRVERLEKQRLANVSCHKVDL 54 + LV GA+G+IG H+ L + GHQV + + RLE HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 HWPENLPALLRD--IDTVYYLVH------GMGEGGDFIAHERQAALNVRDALRQTPVKQL 106 E + L + V+ H + + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 107 IFLSS 111 ++ SS Sbjct: 122 LYASS 126
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 67.5 bits (165), Expect = 8e-15 Identities = 70/370 (18%), Positives = 122/370 (32%), Gaps = 71/370 (19%) Query: 1 MKVLVTGATSGLGRNAVEFLRNKGISVRA---------TGRNEAMGKLLEKMGAEFVHAD 51 MK LVTGA +G + + L G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 104 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 105 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAAGEEVINLLAQANPQT--- 161 +++ ++ SS S+Y + D + +A +K A E L+A Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANE----LMAHTYSHLYGL 171 Query: 162 RFTVLRPQSLFGPHDK--VFIPRLAHMMHHYGSVLLPHGGSALVDMTYYENAIHAMWLAS 219 T LR +++GP + + + + M S+ + + G D TY ++ A+ Sbjct: 172 PATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 220 QPGCDHLPS--------------GRAYNITNGENRTLRSIVQKLIDELTIDCRIRSVPYP 265 R YNI N L +Q L D L I+ + +P Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ 291 Query: 266 MLDMIARSMERFGKKSAKEPPLTHYGVSKLNFDFTLDTTRAQEELGYQPIVTLDEGIERT 325 D+ T DT E +G+ P T+ +G++ Sbjct: 292 PGDV----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNF 324 Query: 326 AAWLRDHGNL 335 W RD + Sbjct: 325 VNWYRDFYKV 334
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 26/160 (16%), Positives = 62/160 (38%), Gaps = 3/160 (1%) Query: 31 FAAAAPLLMHDVGMTAVQFGTASSIYYILYGVSKFGSGLLADRINPRVFLAPVLLVIAMI 90 + P + +D ++ + + + + G L+D++ + L +++ Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFG 92 Query: 91 NVGIGMCNNVTILLTLYCFTAIAQGCGFPP-IAKAISQWYSKSERGGWYSLWNTSHNVGG 149 +V + ++ LL + F A FP + ++++ K RG + L + +G Sbjct: 93 SVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGE 152 Query: 150 ALAPLIASAVITYTGNWRYAFFVPAFITLVQAIISAIFMR 189 + P I + Y W Y +P IT++ ++ Sbjct: 153 GVGPAIGGMIAHYIH-WSYLLLIP-MITIITVPFLMKLLK 190
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 27.9 bits (62), Expect = 0.016 Identities = 11/23 (47%), Positives = 14/23 (60%) Query: 56 AVLDHLAWQWNSDTWRDNWPVSL 78 +L H++W W S NWPVSL Sbjct: 8 EILGHVSWLWASSPLHRNWPVSL 30
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.8 bits (67), Expect = 0.005 Identities = 21/82 (25%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Query: 3 VGMYGSMPFVASSMVVNTFANFKRSSKRRLARHEVIGLKPVLEDIGPDLDEVSFTMRLDT 62 V +G +A F R KRR++ H + P+ IG + T R Sbjct: 223 VRTFGPWMLLALLAGFMAFRVMLRQEKRRVSFHRRLLHLPL---IGR-IARGLNTARYAR 278 Query: 63 TLGVVPLAALSLLRVMHSAQEV 84 TL ++ +A+ LL+ M + +V Sbjct: 279 TLSILNASAVPLLQAMRISGDV 300
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 34.7 bits (79), Expect = 0.002 Identities = 34/123 (27%), Positives = 58/123 (47%), Gaps = 17/123 (13%) Query: 129 AKGLTARE--KELKLSIDRNREAQSRSVEQVIRYKTALAQARTT--ILDAKRAQDELNRS 184 KGL+ +E K +K + N+E V + + + A+A A+ T + K+AQ +L +S Sbjct: 562 TKGLSPQEANKLIKDFLSSNKEL----VGKTLNFNKAVADAKNTGNYDEVKKAQKDLEKS 617 Query: 185 LEKRREL------KMEQLGEAKGQLVRSGVQTTAVAAGVFAAANNTANFNRENKMIGLTA 238 L KR L K+E K ++ + Q + +FA N A NR+ + I Sbjct: 618 LRKREHLEKEVEKKLESKSGNKNKM-EAKAQANSQKDEIFALINKEA--NRDARAIAYAQ 674 Query: 239 DMK 241 ++K Sbjct: 675 NLK 677
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.007 Identities = 16/50 (32%), Positives = 22/50 (44%), Gaps = 1/50 (2%) Query: 31 LVLLGPSGAGKSSLLRVLNLLEMPRSGTLTIAGNHFDFTKTPSDKAIREL 80 +VL G G GKS+L+ L L+ S T G D + + EL Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDF-FSDTHFDIGTGKDSYEQIAGIVAYEL 647
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 30.5 bits (68), Expect = 0.004 Identities = 34/119 (28%), Positives = 50/119 (42%), Gaps = 31/119 (26%) Query: 81 FDAVMAG--MDITPEREKQVLFTTPYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQ 138 D+V+A M + E +QV+ TP DNSAL + QL Q Sbjct: 112 LDSVIASRLMQMALEAARQVIGQTPTVDNSALI-------KQIQQL-----------LQQ 153 Query: 139 KFIMDKHPEITTVPYDSYQNAKLDLQNGRIDAVFGDTAVVTEW-LKANPKLAPVGDKVT 196 + + P++ P DLQ R+D + G T + W L+ +P L P G KV+ Sbjct: 154 EPLFSGKPQLRVHPD--------DLQ--RVDDMLGATLSLHGWRLRGDPTLHPGGCKVS 202
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.3 bits (71), Expect = 0.011 Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 6/106 (5%) Query: 394 LMIGMITFQFSNFSFGIGNAAGLLFAGIML-GFLRANHPTFG-YIPQ--GALNMVKEFGL 449 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 450 MVFMAGVGLSAGSGISNGLGAVGGQM--LIAGLVVSLVPVVICFLF 493 M G G+ AG + +G A + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.2 bits (109), Expect = 1e-08 Identities = 17/80 (21%), Positives = 33/80 (41%) Query: 7 RRANDPKRREKIIQATLEAVKTYGVHAVTHRKIAAIAQVPLGSMTYYFAGMDALLSEAFT 66 + + R+ I+ L GV + + +IA A V G++ ++F L SE + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 67 LFTENMSRQYQDFFAQVTDA 86 L N+ ++ A+ Sbjct: 65 LSESNIGELELEYQAKFPGD 84
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 33/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 218 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFTGGWFI 275 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 276 DRYSRVTVVR-ASALM--GALGIGLIIFVDSDWVA-GVSVILWGLGASLGFPLTISAASD 331 DR + V+ + L ++ S ++ + +L GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 332 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 361 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407 Score = 28.7 bits (64), Expect = 0.042 Identities = 32/135 (23%), Positives = 56/135 (41%), Gaps = 11/135 (8%) Query: 38 IRDILSVSTAEMGAVLFGLSIGSMSGILCS---AWLVKRFGTRKVIRTTMTCAVTGMVIL 94 ++D+ +STAE+G+V+ + G+MS I+ LV R G V+ +T + Sbjct: 283 MKDVHQLSTAEIGSVI--IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTA 340 Query: 95 SVALWCASPLIFALGLAVFGASFGAAEVAINVEGAAVERELNKTVLPMMHGFYSFGTLAG 154 S L S + + + V G + I+ V L + +F + Sbjct: 341 SFLLETTSWFMTIIIVFVLG-GLSFTKTVIS---TIVSSSLKQQEAGAGMSLLNFTSFLS 396 Query: 155 AGVGMALTA--LSVP 167 G G+A+ LS+P Sbjct: 397 EGTGIAIVGGLLSIP 411
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.1 bits (104), Expect = 6e-07 Identities = 66/356 (18%), Positives = 127/356 (35%), Gaps = 51/356 (14%) Query: 48 QAGLDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLATLLAKNIEQ 107 A +WV T+ + G + G LSD++G + ++L G++ + + + Sbjct: 48 PASTNWVNTAFMLTFSIGTAV---YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFS 104 Query: 108 FT-FLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLVGAAWVH 166 RF+QG A+ + + K L+ ++ + +GP +G H Sbjct: 105 LLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAH 164 Query: 167 VLPWEGMFILFAALAAIAFFGLQRAMPETATRRGE------------------------- 201 + W +L + I L + + + +G Sbjct: 165 YIHW-SYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSI 223 Query: 202 ------TLSFKALGRDYRLV---------IKNRRFVAGALALGFVSLPLLAWIAQSPIII 246 LSF + R V KN F+ G L G + + +++ P ++ Sbjct: 224 SFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMM 283 Query: 247 ISGEQLSSYEYG-LLQVPVFGALIAGNLVLARLTSRRTVRSLIVMGGWPIVAGLIIAAAA 305 QLS+ E G ++ P ++I + L RR ++ +G + + A+ Sbjct: 284 KDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS-- 341 Query: 306 TVVSSHAYLWMTAGLSVYAFGIGLANAGLVRLTLFSSDMSKGTVSAAMGMLQMLIF 361 + +MT + V+ G GL+ V T+ SS + + A M +L F Sbjct: 342 -FLLETTSWFMTIII-VFVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF 394
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 47.1 bits (112), Expect = 5e-08 Identities = 49/207 (23%), Positives = 78/207 (37%), Gaps = 25/207 (12%) Query: 1 MTQYASSLRSLAAGSVLLFLFASPVKAEEQTIAPPGVDAR-AWILMDYASGKVLAEGNAD 59 M + SL A ++ L + ASP E+ ++ + R I MD ASG+ L AD Sbjct: 1 MRYIRLCIISLLA-TLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRAD 59 Query: 60 EKLDPASLTKIMTSYVVGQALKAGKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQV 119 E+ S K++ V + AG +L + + +P V D + Sbjct: 60 ERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGM 113 Query: 120 SVADLNKGIIIQSGNDACIALADYVAGSQESFIGLMNAYAKRLGLTNTT---FQTVHGLD 176 +V +L I S N A L V G + A+ +++G T ++T Sbjct: 114 TVGELCAAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEA 168 Query: 177 APGQF---STARDMA------LLGKAL 194 PG +T MA L + L Sbjct: 169 LPGDARDTTTPASMAATLRKLLTSQRL 195
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 30.8 bits (69), Expect = 0.013 Identities = 17/55 (30%), Positives = 24/55 (43%), Gaps = 5/55 (9%) Query: 230 VLQTAKALGIPVKGHVEQLSLLGGAQLVSRYQGLSADHIEYLDEAGVAAMRDGGT 284 VL+ +P G +S+LG ++L L HI AGVAAM+ Sbjct: 202 VLRDTNVTAVPASGAPAAVSVLGASELT-----LDGGHITGGRAAGVAAMQGAVV 251
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.022 Identities = 2/39 (5%), Positives = 19/39 (48%) Query: 56 LTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVMERQKQI 94 + + + + + +++ + Q+++ + ++ E + + Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV 292
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 115 bits (289), Expect = 2e-33 Identities = 36/119 (30%), Positives = 55/119 (46%), Gaps = 4/119 (3%) Query: 56 EEQARLQMQQLQQNNIVYFDLDKYDIRSDFAAMLDAHANFLRSN--PSYKVTVEGHADER 113 +Q + + V F+ +K ++ + A LD + L + V V G+ D Sbjct: 205 APAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI 264 Query: 114 GTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDEAAYAKNRRAVL 172 G+ YN L ERRA +V YL KG+ AD+IS G+ P V G+ K R A++ Sbjct: 265 GSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESNP-VTGN-TCDNVKQRAALI 321
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.8 bits (147), Expect = 5e-12 Identities = 28/199 (14%), Positives = 66/199 (33%), Gaps = 6/199 (3%) Query: 64 YNRQQDQQASARRAEEERKKLQQQQAEELQQKQAAEQERLKQLEKERLAAQEQQKQAEEA 123 YN + +++ Q E R+ + A + E Sbjct: 981 YNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETV 1040 Query: 124 AKLAQQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKKKAEAEAVKAAADAKKKAEAEAA 183 A+ ++Q+ + E+ + A + + A +A ++ K + V A+ +E + Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEV-----AQSGSETKET 1095 Query: 184 KAAADAKKKAEAEAAKAAAEAKKKAEAEAAKAAAEAKKKADAAAAKAAAEAKKKADAAAA 243 + + + KA E +K E + + K+ + + AE ++ D Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQE-VPKVTSQVSPKQEQSETVQPQAEPARENDPTVN 1154 Query: 244 KAAADAKKKAAAEKAAAAE 262 ++ A+ A+ Sbjct: 1155 IKEPQSQTNTTADTEQPAK 1173 Score = 53.5 bits (128), Expect = 8e-10 Identities = 29/184 (15%), Positives = 62/184 (33%), Gaps = 4/184 (2%) Query: 55 VDPGAVVQQYNRQQDQQASARRAEEERKKLQQQQAEELQQKQAAEQERLKQLEKERLAAQ 114 VD + N Q D S EE ++ + +E E + ++ Sbjct: 992 VDTTNITTPNNIQADVP-SVPSNNEEIARVDEAPVPPPAPATPSETTETVA-ENSKQESK 1049 Query: 115 EQQKQAEEAAKLAQQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKKKAEAEAVKAAADA 174 +K ++A + Q ++ A+EA + E + + + E + A + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE-TATVEK 1108 Query: 175 KKKAEAEAAKAAADAKKKAEAEAAKAAAEA-KKKAEAEAAKAAAEAKKKADAAAAKAAAE 233 ++KA+ E K K ++ + +E + +AE K+ + A Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 234 AKKK 237 + Sbjct: 1169 EQPA 1172 Score = 53.1 bits (127), Expect = 1e-09 Identities = 24/219 (10%), Positives = 71/219 (32%), Gaps = 21/219 (9%) Query: 66 RQQDQQASARRAEEERKKLQQQQAEE--LQQKQAAEQER------LKQLEKERLAAQEQQ 117 + A + E + + +Q A E Q ++ A++ + + E + ++ ++ Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKE 1094 Query: 118 KQ-----------AEEAAKLAQQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKKKAEAE 166 Q EE AK+ ++ Q E + + K+ ++E + A+ ++ + Sbjct: 1095 TQTTETKETATVEKEEKAKVETEKTQ--EVPKVTSQVSPKQEQSETVQPQAEPARENDPT 1152 Query: 167 AVKAAADAKKKAEAEAAKAAADAKKKAEAEAAKAAAEAKKKAEAEAAKAAAEAKKKADAA 226 ++ A+ + A + E ++ + E + A + Sbjct: 1153 VNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVN 1212 Query: 227 AAKAAAEAKKKADAAAAKAAADAKKKAAAEKAAAAEGVD 265 + + + + + ++ + D Sbjct: 1213 SESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCD 1251 Score = 46.6 bits (110), Expect = 2e-07 Identities = 24/215 (11%), Positives = 60/215 (27%), Gaps = 6/215 (2%) Query: 59 AVVQQYNRQQDQQASARRAEEERKKLQQQQAEELQQKQAAEQERLKQLEKERLAAQEQQK 118 A Q Q + E K+ + EE + + + + E ++ +Q K Sbjct: 1078 ANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ-----EVPKVTSQVSPK 1132 Query: 119 QAEEAAKLAQQQQQQAEEAAKAAADAKKKAEAEAAKAAADAKKKAEAEAVKAAADAKKKA 178 Q + Q + + + + + + A + + E + Sbjct: 1133 QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTG 1192 Query: 179 EAEAAKAAADAKKKAEAEAAKAAAEAKKKAEAEAAKAAAEAKKKADAAAAKAAAEAKKKA 238 + + ++ K + ++ + A ++ + A Sbjct: 1193 NSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDL 1252 Query: 239 DAAAAKAA-ADAKKKAAAEKAAAAEGVDDLLGDLS 272 + A +DA+ KA + V + L Sbjct: 1253 TSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLE 1287
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 31.0 bits (70), Expect = 0.004 Identities = 12/41 (29%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDNAPRMQDYTLEGEEGRDM-MLLDALIQLKEKDPSLSFRR 53 ++N + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.006 Identities = 11/33 (33%), Positives = 16/33 (48%), Gaps = 6/33 (18%) Query: 50 KIDFTLTEGNRLALIGHNGSGKTTLLRVLAGAY 82 K D+++ L G G GK+TL+ L G Sbjct: 594 KFDYSVV------LEGTGGIGKSTLINTLVGLD 620
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 30.0 bits (67), Expect = 0.008 Identities = 14/51 (27%), Positives = 22/51 (43%), Gaps = 4/51 (7%) Query: 20 LTLVSSANIACGFHAGDAQTMLT---CVREALKNGVAIGAHPSFPDRDNFG 67 + + IA G G T+LT V + A+ A PS ++DN+ Sbjct: 95 VEAPTGTFIASGVVVGK-DTLLTNKHVVDATHGDPHALKAFPSAINQDNYP 144
>STREPTOPAIN#Streptopain (C10) cysteine protease family signature. Length = 398 Score = 31.2 bits (70), Expect = 0.011 Identities = 17/73 (23%), Positives = 33/73 (45%), Gaps = 1/73 (1%) Query: 2 LDTNMKTQLRAYLEKLTKPVELIATLDDS-AKSAEIKELLAEIAELSDKVTFKEDNTLPV 60 D N K + +++E + ++ LD + A +AEIK+ + + S + + + N + Sbjct: 109 FDANGKENIASFMESYVEQIKENKKLDTTYAGTAEIKQPVVKSLLDSKGIHYNQGNPYNL 168 Query: 61 RKPSFLITNPGSQ 73 P PG Q Sbjct: 169 LTPVIEKVKPGEQ 181
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 28.4 bits (63), Expect = 0.019 Identities = 18/98 (18%), Positives = 41/98 (41%), Gaps = 13/98 (13%) Query: 30 QGITILKSFEAPGGMKGYLGKYQDMGVTIYLTPDGKHAISG--YMYNEKGENLSNALIEK 87 + + + FE YLGK+ ++ + G ++ + N+ G ++ N Sbjct: 21 ESVKPVSDFEL----NNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLN----- 71 Query: 88 EIYAPAGREMWQKMEKASWILDGKKDAPVVLYVFADPF 125 Y+ + W++ E ++ ++G D + + F PF Sbjct: 72 RGYSEE-KGEWKEAEGKAYFVNGSTDGYLKVSFFG-PF 107
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 337 bits (866), Expect = e-120 Identities = 105/257 (40%), Positives = 148/257 (57%), Gaps = 20/257 (7%) Query: 9 KTVWVTGAGKGIGYATALAFVDAGARVFGFDRE---------------FTQENYPFATEV 53 K ++TGA +GIG A A GA + D E +P Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP----- 63 Query: 54 MDVADAAQVAQVCQRVLQKTPRLDVLVNAAGILRMGATDALSVDDWQQTFAVNVGGAFNL 113 DV D+A + ++ R+ ++ +D+LVN AG+LR G +LS ++W+ TF+VN G FN Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 114 FSQTMAQFRRQQGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALTVGLELAGCGVRCN 173 ++ G+IVTV S+ A PR M+AY +SKAA +GLELA +RCN Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 174 VVSPGSTDTDMQRTLWVSEDAEQQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 233 +VSPGST+TDMQ +LW E+ +Q I+G E FK GIPL K+A+P +IA+ +LFL S A Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 234 SHITLQDIVVDGGSTLG 250 HIT+ ++ VDGG+TLG Sbjct: 244 GHITMHNLCVDGGATLG 260
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 424 bits (1092), Expect = e-153 Identities = 147/299 (49%), Positives = 192/299 (64%), Gaps = 18/299 (6%) Query: 1 MAIPKLQSYALPTALDIPTNKVNWAFEPERAALLIHDMQDYFVSFWGRNCPMMDQVIANI 60 MAIP +Q Y +PTA D+P NKV+W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRQYCKEHHIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVEALTPDEADTV 120 L+ C + IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P++ D V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKDTGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRKEHLMALNYVAGRSGRVVMTESLL------PTPVPASKA-----------ALRALIL 223 FS ++H MAL Y AGR VMT+SLL P V + A +R I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDETDEPLD-DENLIDYGLDSVRMMGLAARWRKVHGDIDFVMLAKNPTIDAWWALLS 281 LL ET E + E+L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W LL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 59.6 bits (144), Expect = 3e-12 Identities = 46/210 (21%), Positives = 80/210 (38%), Gaps = 21/210 (10%) Query: 105 EPNAETVAAQMPDLILISATGGDSALALYDQLSAIAPTLVINYDDKS-----WQSLLTQL 159 EPN E + P ++ SA G S + L+ IAP N+ D + LT++ Sbjct: 86 EPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPLAMARKSLTEM 141 Query: 160 GEITGQEKQAAARIAEFEAQLTTVKQRIALPPQPVSALVYTPAAHSANLWTPESAQGKLL 219 ++ + A +A++E + ++K R L ++ P S ++L Sbjct: 142 ADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEIL 201 Query: 220 TQLGFTLATLPRGLQTSKSQGKRHDIIQLGGENLAAGLNGQSLFLFAGDNKDVAALYTNP 279 + G A + + + + LAA + L ++KD+ AL P Sbjct: 202 DEYGIPNAW--------QGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATP 253 Query: 280 LLAHLPAVQNKRVYALGTETFRLDYYSATL 309 L +P V+ R + F Y ATL Sbjct: 254 LWQAMPFVRAGRFQRVPAVWF----YGATL 279
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.7 bits (64), Expect = 0.048 Identities = 69/397 (17%), Positives = 130/397 (32%), Gaps = 66/397 (16%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQVGLSVTLTGGAMFIGLMVGGVLADRYERKKVIL 86 F S+++ +L V++P T IG V G L+D+ K+++L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 87 LARGTCGIGFIGLCVNALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQ 146 G + V ++A ++ G F +L ++ + +EN + Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL----VMVVVARYIPKENRGK 139 Query: 147 AGAITMLTVRLGSVISPMLGGILLASGGVAWNYGLAAAGTFITLLPLLTLPRLPVPPQPR 206 A + V +G + P +GG++ + W+Y L IT++ + L +L Sbjct: 140 AFGLIGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIP--MITIITVPFLMKLLKKEVRI 195 Query: 207 ------------------------------------------------ENPFIAL-LAAF 217 +PF+ L Sbjct: 196 KGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKN 255 Query: 218 RFLLASPLIGGIALLGGLVTMASAVRVLYPALAMSWQMSAAQIGLLYAAI-PLGAAIGAL 276 + L GGI T+A V ++ + Q+S A+IG + + I Sbjct: 256 IPFMIGVLCGGIIF----GTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 277 TSGQLAHSVRPGLIMLVSTVG---SFLAVGLFAIMPVWIAGVICLALFGWLSAISSLLQY 333 G L P ++ + SFL W +I + + G LS +++ Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIST 371 Query: 334 TLLQTQTPENMLGRMNGLWTAQNVTGDAIGAALLGGL 370 + + + M L + + G A++GGL Sbjct: 372 IVSSSLKQQEAGAGM-SLLNFTSFLSEGTGIAIVGGL 407
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 32.9 bits (75), Expect = 1e-05 Identities = 8/24 (33%), Positives = 17/24 (70%) Query: 8 FAMIGGMITAPLLSLFIIPAAYKL 31 ++GGM++A LL++F +P + + Sbjct: 1004 IGVMGGMVSATLLAIFFVPVFFVV 1027
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 2e-16 Identities = 29/122 (23%), Positives = 58/122 (47%), Gaps = 2/122 (1%) Query: 1 MKPASVIIMDEHPIVRMSIEVLLGKNSNIQVVLKTDDSRTAIEYLRTYPVDLVILDIELP 60 M A++++ D+ +R + L + V T ++ T ++ DLV+ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYD--VRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GTDGFTLLKRIKSIQEHTRILFLSSKSEAFYAGRAIRAGANGFVSKRKDLNDIYNAVKMI 120 + F LL RIK + +L +S+++ A +A GA ++ K DL ++ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LS 122 L+ Sbjct: 119 LA 120
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 115 bits (291), Expect = 8e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIEKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.002 Identities = 34/133 (25%), Positives = 68/133 (51%), Gaps = 15/133 (11%) Query: 191 ERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPD- 249 LE A +E + +L R +++ ++ S+ +Q++A ++L E + + Sbjct: 291 AALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK---KQLEAEHQKLEEQNKISEA 344 Query: 250 ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDWMVQVPWNARSK 308 ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D + A+ + Sbjct: 345 SRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE----AKKQ 397 Query: 309 VKKDLRQAQEILD 321 V+K L +A L Sbjct: 398 VEKALEEANSKLA 410
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.0 bits (96), Expect = 9e-06 Identities = 40/190 (21%), Positives = 76/190 (40%), Gaps = 15/190 (7%) Query: 221 RNNAWLI-LLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYG 279 R+N LI L ++ + + + ++++ + VN L +I A+YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 280 GILMQRLSLFRALLIFGILQGASNAGYWLLSITDKNMFSMGAAVFFENLCGGMGTAAFVA 339 L +L + R LL I+ + ++ + FS+ + G G AAF A Sbjct: 71 K-LSDQLGIKRLLLFGIIINCFGS----VIGFVGHSFFSL---LIMARFIQGAGAAAFPA 122 Query: 340 LLM----TLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAH-GWPTFYLFSVVAAVP 394 L+M K F L+ ++ A+G VGP G + + W L ++ + Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMG-EGVGPAIGGMIAHYIHWSYLLLIPMITIIT 181 Query: 395 GLLLLLVCRQ 404 L+ + ++ Sbjct: 182 VPFLMKLLKK 191
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 85.3 bits (211), Expect = 4e-20 Identities = 84/383 (21%), Positives = 149/383 (38%), Gaps = 26/383 (6%) Query: 16 GLGTVFSLRMLGMFMVLPVLTTY--GMALQGASEALIGIAIGIYGLAQAIFQIPFGLLSD 73 L TV L +G+ +++PVL + A GI + +Y L Q G LSD Sbjct: 10 ILSTVA-LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSD 68 Query: 74 RIGRKPLIVGGLAVFVAGSVIAALSHSIWGIILGRALQG-SGAIAAAVMALLSDLTREQN 132 R GR+P+++ LA I A + +W + +GR + G +GA A A ++D+T Sbjct: 69 RFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDE 128 Query: 133 RTKAMAFIGVSFGITFAIAMVLGPIVTHSLGLNALFWMIAALATLGILLTIWVVPNSTNH 192 R + F+ FG VLG ++ +A F+ AAL L L +++P S Sbjct: 129 RARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 193 VLNRESGMVKGSFSKVLAEPRLLKLNFGIMCLHILLMSTFVA-LPGQLADAGFPAAEHWK 251 + + G+ + L+ F+ L GQ+ A + + Sbjct: 188 ERRPLRREALNPLAS-------FRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDR 240 Query: 252 VYLATMVIAFA--------AVVPFIIYAEVKRRMKQVFLFCVGLII-VAEIVLWGAGQHF 302 + I + ++ +I V R+ + +G+I +L Sbjct: 241 FHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRG 300 Query: 303 WELVIGVQLFFLAFNLMEAL---LPSLISKESPAGYKGTAMGVYSTSQFLGVALGGSLGG 359 W + L M AL L + +E +G+ + S + +G L ++ Sbjct: 301 WMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA 360 Query: 360 WIDGTFDGQTVFLAGAVLAMVWL 382 T++G ++AGA L ++ L Sbjct: 361 ASITTWNG-WAWIAGAALYLLCL 382
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 56.4 bits (136), Expect = 7e-11 Identities = 56/306 (18%), Positives = 108/306 (35%), Gaps = 17/306 (5%) Query: 19 FTSWMLDAFDFFILVFVLSDLAEWFHAS---VSDVSIAIMLTLAVRPIGALLFGRMAEKY 75 ++ LDA +++ VL L S + I + L ++ A + G +++++ Sbjct: 11 LSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF 70 Query: 76 GRRPILMLNILFFTVFELLSAWSPTFMAFLIFRVMYGVAMGGIWGVASSLAMETIPDRSR 135 GRRP+L++++ V + A +P I R++ G+ G VA + + R Sbjct: 71 GRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDER 129 Query: 136 ----GLMSGIFQAGYPCGYLFASVIFGLFYSMVGWRGMFLIGA---LPVVLLPYIWFKVP 188 G MS F G + A + G F A L Sbjct: 130 ARHFGFMSACFGFG-----MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 189 ESPVWLAARARKENTALLPVLRKQWKLCLYLVLVMAFFNFFSHGTQDLYPTFLKMQHGFD 248 R N + + L+ V L+ F + + +D Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 249 PHLISI-IAIFYNIAAMLGGIFYGTLSERIGRKKAIMIAAFLALPVLPLWAFSSGSFTIG 307 I I +A F + ++ + G ++ R+G ++A+M+ L AF++ + Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 308 LGAFLM 313 L+ Sbjct: 305 PIMVLL 310 Score = 33.6 bits (77), Expect = 0.001 Identities = 37/186 (19%), Positives = 77/186 (41%), Gaps = 10/186 (5%) Query: 3 TPLNWTTTQRHVAFASFTSWMLDAF-DFFILVFVLSDLAEWFHASVSDVSIAIMLTLAVR 61 W VA +++ ++V+ + FH + + I++ + Sbjct: 201 ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG-EDRFHWDATTIGISLAAFGILH 259 Query: 62 PIG-ALLFGRMAEKYGRRPILMLNILF-FTVFELLSAWSPTFMAFLIFRVMYGVAMG--G 117 + A++ G +A + G R LML ++ T + LL+ + +MAF I ++ +G Sbjct: 260 SLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPA 319 Query: 118 IWGVASSLAMETIPDRSRGLMSGIFQAGYPCGYLFASVIFGLFYSMVGWRG-MFLIGA-L 175 + + S E + +G ++ + G L + I+ S+ W G ++ GA L Sbjct: 320 LQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYA--ASITTWNGWAWIAGAAL 377 Query: 176 PVVLLP 181 ++ LP Sbjct: 378 YLLCLP 383
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 48.3 bits (115), Expect = 4e-08 Identities = 18/112 (16%), Positives = 37/112 (33%), Gaps = 7/112 (6%) Query: 74 ELRSRVGGTLDAVSVPEGRLVSRGQLLFQIDPRPFEVALDTAVAQLRQAEVLARQAQADF 133 E++ + + V EG V +G +L ++ E + L QA + + Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 134 DRIQR-------LVASGAVSRKNADDVTATRNARQAQMQSAKAAVAAARLEL 178 I+ L + ++V + + Q + + L L Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Score = 34.4 bits (79), Expect = 7e-04 Identities = 20/106 (18%), Positives = 37/106 (34%), Gaps = 13/106 (12%) Query: 112 LDTAVAQLRQAEVLARQAQADFDRIQRLVASGAVSRKNADDVTATRNARQAQMQSAKAAV 171 L +QL Q E A+ ++ + +L + ++ + + Sbjct: 268 LRVYKSQLEQIESEILSAKEEYQLVTQLFKN---------EILDKLRQTTDNIGLLTLEL 318 Query: 172 AAARLELSWTRITAPIAGRVDRILVTRGNLVSGGVAGNATLLTTIV 217 A + I AP++ +V ++ V GGV A L IV Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKVHT----EGGVVTTAETLMVIV 360
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1046 bits (2706), Expect = 0.0 Identities = 435/1040 (41%), Positives = 660/1040 (63%), Gaps = 19/1040 (1%) Query: 6 FFIARPIFAIVLSLLMLLAGAIAFLKLPLSEYPAVTPPTVQVSASYPGANPQVIADTVAA 65 FFI RPIFA VL++++++AGA+A L+LP+++YP + PP V VSA+YPGA+ Q + DTV Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLEQVINGVDGMLYMNTQMAIDGRMVISIAFEQGTDPDMAQIQVQNRVSRALPRLPEEVQ 125 +EQ +NG+D ++YM++ G + I++ F+ GTDPD+AQ+QVQN++ A P LP+EVQ Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 126 RIGVVTEKTSPDMLMVVHLVSPQKRYDSLYLSNFAIRQVRDELARLPGVGDVLVWGAGEY 185 + G+ EK+S LMV VS +S++ V+D L+RL GVGDV ++G +Y Sbjct: 124 QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQY 182 Query: 186 AMRVWLDPAKIANRGLTASDIVTALREQNVQVAAGSVGQQPEASA-AFQMTVNTLGRLTS 244 AMR+WLD + LT D++ L+ QN Q+AAG +G P ++ R + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 245 EEQFGEIVVKIGADGEVTRLRDVARVTLGADAYTLRSLLNGEAAPALQIIQSPGANAIDV 304 E+FG++ +++ +DG V RL+DVARV LG + Y + + +NG+ A L I + GANA+D Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 305 SNAIRGKMDELQQNFPQDIEYRIAYDPTVFVRASLQSVAITLLEALVLVVLVVVLFLQTW 364 + AI+ K+ ELQ FPQ ++ YD T FV+ S+ V TL EA++LV LV+ LFLQ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 365 RASIIPLVAVPVSLVGTFALMHLFGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHISQ 424 RA++IP +AVPV L+GTFA++ FG+S+NTL++FG+VL+IG++VDDAIVVVENVER + + Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 425 GKSPG-EAAKKAMDEVTGPILSITSVLTAVFIPSAFLAGLQGEFYRQFALTIAISTILSA 483 K P EA +K+M ++ G ++ I VL+AVFIP AF G G YRQF++TI + LS Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 484 INSLTLSPALAAILLRPHHDTAKADWLTRLMGTVTGGFFHRFNRFFDSASNRYVSAVRRA 543 + +L L+PAL A LL+P ++ GGFF FN FD + N Y ++V + Sbjct: 483 LVALILTPALCATLLKP---------VSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 544 VRGSVIVMVLYAGFVGLTWLGFHQVPNGFVPAQDKYYLVGIAQLPSGASLDRTEAVVKQM 603 + + +++YA V + F ++P+ F+P +D+ + + QLP+GA+ +RT+ V+ Q+ Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQV 593 Query: 604 SAIALA--EPGVESVVVFPGLSVNGPVNVPNSALMFAMLKPFDEREDPSLSANAIAGKLM 661 + L + VESV G S +G N+ + F LKP++ER SA A+ + Sbjct: 594 TDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 662 HKFSHIPDGFIGIFPPPPVPGLGATGGFKLQIEDRAELGFEAMTKVQSEIMSKAMQTP-E 720 + I DGF+ F P + LG GF ++ D+A LG +A+T+ +++++ A Q P Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 721 LANMLASFQTNAPQLQVDIDRVKAKSMGVSLTDIFETLQINLGSLYVNDFNRFGRTWRVM 780 L ++ + + Q ++++D+ KA+++GVSL+DI +T+ LG YVNDF GR ++ Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 781 AQADAPFRMQQEDIGLLKVRNAKGEMIPLSAFVTIMRQSGPDRIIHYNGFPSVDISGGPA 840 QADA FRM ED+ L VR+A GEM+P SAF T G R+ YNG PS++I G A Sbjct: 772 VQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAA 831 Query: 841 PGFSSGQATDAIEKIVRETLPEGMVFEWTDLVYQEKQAGNSALAIFALAVLLAFLILAAQ 900 PG SSG A +E + + LP G+ ++WT + YQE+ +GN A A+ A++ ++ FL LAA Sbjct: 832 PGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAAL 890 Query: 901 YNSWSLPFAVLLIAPMSLLSAIVGVWVSGGDNNIFTQIGFVVLVGLAAKNAILIVEFAR- 959 Y SWS+P +V+L+ P+ ++ ++ + N+++ +G + +GL+AKNAILIVEFA+ Sbjct: 891 YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKD 950 Query: 960 AKEHDGADPLTAVLEASRLRLRPILMTSFAFIAGVVPLVLATGAGAEMRHAMGIAVFAGM 1019 E +G + A L A R+RLRPILMTS AFI GV+PL ++ GAG+ ++A+GI V GM Sbjct: 951 LMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 1020 LGVTLFGLLLTPVFYVVVRR 1039 + TL + PVF+VV+RR Sbjct: 1011 VSATLLAIFFVPVFFVVIRR 1030 Score = 89.5 bits (222), Expect = 4e-20 Identities = 68/427 (15%), Positives = 143/427 (33%), Gaps = 36/427 (8%) Query: 643 FDEREDPSLSANAIAGKLMHKFSHIPDGFIGIFPPPPVPGLGATGGFKLQIEDRAELGFE 702 F DP ++ + KL +P + ++ + + ++ Sbjct: 94 FQSGTDPDIAQVQVQNKLQLATPLLPQEV----QQQGISVEKSSSSYLMVAGFVSDNP-- 147 Query: 703 AMTKVQSEIMSKAMQTPELANM--LASFQTNAPQLQVDI--DRVKAKSMGVSLTDIFETL 758 T+ + L+ + + Q Q + I D ++ D+ L Sbjct: 148 GTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQL 207 Query: 759 QIN--------LGSLYVNDFNRFGRTWRVMAQADAPFRMQQEDIGLLKVR-NAKGEMIPL 809 ++ LG + + + P E+ G + +R N+ G ++ L Sbjct: 208 KVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP-----EEFGKVTLRVNSDGSVVRL 262 Query: 810 SAFVTIMRQSGPDRII-HYNGFPSVDISGGPAPGFSSGQATDAIEKIV---RETLPEGM- 864 + +I NG P+ + A G ++ AI+ + + P+GM Sbjct: 263 KDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMK 322 Query: 865 ---VFEWTDLVYQEKQAGNSALAIFALAVLLAFLILAAQYNSWSLPFAVLLIAPMSLLSA 921 ++ T V + + + + A++L FL++ + + P+ LL Sbjct: 323 VLYPYDTTPFV---QLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGT 379 Query: 922 IVGVWVSGGDNNIFTQIGFVVLVGLAAKNAILIVE-FARAKEHDGADPLTAVLEASRLRL 980 + G N T G V+ +GL +AI++VE R D P A ++ Sbjct: 380 FAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQ 439 Query: 981 RPILMTSFAFIAGVVPLVLATGAGAEMRHAMGIAVFAGMLGVTLFGLLLTPVFYVVVRRM 1040 ++ + A +P+ G+ + I + + M L L+LTP + + Sbjct: 440 GALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKP 499 Query: 1041 ALKRENR 1047 + Sbjct: 500 VSAEHHE 506
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 28.8 bits (64), Expect = 0.042 Identities = 21/70 (30%), Positives = 27/70 (38%), Gaps = 4/70 (5%) Query: 75 AIALRNNRDLRKAGLNVEAARALYRIQRAEMLPTLGIATAMDAGRTPADLSVMDEPEINR 134 AIA+RNN A VE +R R + L D R PADL + + R Sbjct: 155 AIAMRNN----DAPALVEEVYNFFRDSRDPVHQALNWMILGDFNREPADLEMNLTVPVRR 210 Query: 135 RYEMAGATTA 144 E+ A Sbjct: 211 ASEIISPAAA 220
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 134 bits (339), Expect = 7e-43 Identities = 59/183 (32%), Positives = 88/183 (48%), Gaps = 21/183 (11%) Query: 1 MKRRSSFLVFLGLLLASPLALANDQHTVSFGYAQTHLSSLKNSDSKDLRGFNFKYRYEFN 60 MK+ + +L + TV+ GYAQ+ N + GFN KYRYE + Sbjct: 1 MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMN----KMGGFNLKYRYEED 56 Query: 61 ET-WGMLGSFTATRNEMENYTWKEGKLHKNGSDSVDYGSLMFGPTYRFNDYVSLYGNAGI 119 + G++GSFT T + K Y + GP YR ND+ S+YG G+ Sbjct: 57 NSPLGVIGSFTYTEKSRTASSGDYNK--------NQYYGITAGPAYRINDWASIYGVVGV 108 Query: 120 ATMKF--------NKHSKEDSFAYGAGVIFNPVKSISIDASWEASRFFAVDTNTFGVSVG 171 KF + + F+YGAG+ FNP++++++D S+E SR +VD T+ VG Sbjct: 109 GYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDVGTWIAGVG 168 Query: 172 YRF 174 YRF Sbjct: 169 YRF 171
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 759 bits (1962), Expect = 0.0 Identities = 262/880 (29%), Positives = 417/880 (47%), Gaps = 63/880 (7%) Query: 4 TINLNRKS-LALLIAIVCSGSAQG----EEYYFDPALLQGATYGQ-NIARFNE-QQTPSG 56 I +R + + + + C+ +AQ E YF+P L +++RF Q+ P G Sbjct: 17 HIRKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPG 76 Query: 57 DYLADVYVNGTLVTASTNIRFDAVKEGQQTEPCLPLSVMKAAQIKSLPATDAA----TEC 112 Y D+Y+N + A+ ++ F+ Q PCL + + + + + + C Sbjct: 77 TYRVDIYLNNGYM-ATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDAC 135 Query: 113 RPLREWVPHAGWQFDSATLRLLLTIPMTELTHKPRGYISPSEWDSGALALFLRHNTNWTH 172 PL + A Q D RL LTIP ++++ RGYI P WD G A L +N + Sbjct: 136 VPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNS 195 Query: 173 TENTDSHYRYQYLWSGLNMGVNLGLWQVRHQSNLRYANSNQS-GSAWRYNSVRTWVQRPV 231 +N Y + L G+N+G W++R + Y +S+ S GS ++ + TW++R + Sbjct: 196 VQN-RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDI 254 Query: 232 ASINSILSLGDSYTDSSLFGSLSFNGAKLVTDERMRPQGKRGYAPEVRGVAASSAHVVVK 291 + S L+LGD YT +F ++F GA+L +D+ M P +RG+AP + G+A +A V +K Sbjct: 255 IPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIK 314 Query: 292 QLGKVIYETNVPPGPFYIDDLYNTRYQGDLEVEVIEASGKTSRFTVPYSSVPDSVRPGNW 351 Q G IY + VPPGPF I+D+Y GDL+V + EA G T FTVPYSSVP R G+ Sbjct: 315 QNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHT 374 Query: 352 HYSLAFGRVRQYY--DIENRFFEGTFQHGVNNTITLNLGSRIAQRYQAWLAGGVWATGM- 408 YS+ G R + RFF+ T HG+ T+ G+++A RY+A+ G G Sbjct: 375 RYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGAL 434 Query: 409 GAFGLNATWSNARAEHNARQQGWRAELSYSKTFT-TGTNLVLAAYRYSTNGFRDLQDVLG 467 GA ++ T +N+ +++ G Y+K+ +GTN+ L YRYST+G+ + D Sbjct: 435 GALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTY 494 Query: 468 VRREAKTGI-------------DYYSDTLHQRNRLSATVSQPLGRLGTLNLSASTADYYN 514 R DYY+ ++R +L TV+Q LGR TL LS S Y+ Sbjct: 495 SRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWG 554 Query: 515 NQSRITQLQMGYSNQWRNISYGVNIARQRTTWDYDRFYHGVNEPLDVSSRQKYTETTMSF 574 + Q Q G + + +I++ ++ + + W + ++ Sbjct: 555 TSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKG------------------RDQMLAL 596 Query: 575 NVSIPLDWGENRTSVA------MNYNQSSQSRSSTISMTGSSG---ENSDLSWSVYGGYE 625 NV+IP S + +Y+ S ++ G G E+++LS+SV GY Sbjct: 597 NVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYA 656 Query: 626 RYRNSNSDSSAPTTFGGNLQQNTRFGALRANYDQGDNYRQEGLGASGTLVLHSGGLTAGP 685 + NS S+ L +G Y D+ +Q G SG ++ H+ G+T G Sbjct: 657 GGGDGNSGSTG----YATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQ 712 Query: 686 YTSDTFALIHADGAQGAIVQNGQGAVVDRFGYAILPSLSPYRVNNVTLDTRKMRSDAELT 745 +DT L+ A GA+ A V+N G D GYA+LP + YR N V LDT + + +L Sbjct: 713 PLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLD 772 Query: 746 GGSQQIVPYAGAIARVNFATISGKAVLISVKMPDGGIPPMGADVFNGEGTNIGMVGQSGQ 805 +VP GAI R F G +L+++ + P GA V + + G+V +GQ Sbjct: 773 NAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQ 831 Query: 806 IYARIAHPSGSLLVRWGTGANQRCRVAYQLDLHTKEPFLY 845 +Y +G + V+WG N C YQL +++ L Sbjct: 832 VYLSGMPLAGKVQVKWGEEENAHCVANYQLPPESQQQLLT 871
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 45.8 bits (108), Expect = 4e-07 Identities = 29/137 (21%), Positives = 55/137 (40%), Gaps = 14/137 (10%) Query: 291 DSIPNEAEKMDEEKIVALINKAIDARMAKAD---EETDAKAKADAEEEARKEKADAEEKE 347 P A + + VA +K + K + ET A+ + A+E KA+ + E Sbjct: 1025 VPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE 1084 Query: 348 AEEAKAKA-DAEEKAAKEKADAEAKEKADAE-----EAERMAKEKADSQLRQEIAEL--- 398 ++ ++ + + KE A E +EKA E E ++ + + Q + E + Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAE 1144 Query: 399 --RSRIPTELSDEERNE 413 R PT E +++ Sbjct: 1145 PARENDPTVNIKEPQSQ 1161 Score = 45.1 bits (106), Expect = 6e-07 Identities = 38/200 (19%), Positives = 69/200 (34%), Gaps = 12/200 (6%) Query: 315 ARMAKADEETDAKAKADAEEEARKEKADAE-EKEAEEAKAKADAEEKAAKEKADAEAKEK 373 A+ +ET + ++EKA E EK E K + K + + E Sbjct: 1086 AQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEP 1145 Query: 374 ADAEEAERMAKEKADSQLR-----QEIAELRSRIPTELSDEERNEIADAQVKADSVFSCF 428 A + KE Q E S + +++ ++ V+ + Sbjct: 1146 ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205 Query: 429 GKRAPVPLSGEKPLAYRRRLMIQLQEHSPDFKTV---DLSTIADSALLSVAEKTIYADAQ 485 + V R R ++ H+ + T D ST+A L S + +DA+ Sbjct: 1206 TTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDAR 1265 Query: 486 KSA---SLSVGPGMLREIKR 502 A +L+VG + + I + Sbjct: 1266 AKAQFVALNVGKAVSQHISQ 1285
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 32.1 bits (72), Expect = 0.001 Identities = 31/130 (23%), Positives = 47/130 (36%), Gaps = 10/130 (7%) Query: 26 YSRGYQRADTSWKLQWAQRDLTDATITLQREVTERAKEQRRQHAADEERKRADEELAKIQ 85 Y R R + + T+A +LQ + AA + A A+ Q Sbjct: 173 YMRFLDREMEGLTAAYNVKLFTEAISSLQIRMN-------TLTAAKASIEAAAANKAREQ 225 Query: 86 ADADAAERARGGLQQQLAAVQ-RQLAGSETGRLSALAAASQ--AKAETGILLAQLLGEAD 142 A A+A +A +QQ A A G + A AA A+ LAQ + +A Sbjct: 226 AAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAI 285 Query: 143 DLAGKFAKEA 152 + G+ A Sbjct: 286 AVLGRVLASA 295
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 26.3 bits (57), Expect = 0.042 Identities = 22/89 (24%), Positives = 35/89 (39%), Gaps = 3/89 (3%) Query: 3 IDKQALREEFRYMQVHYSDPADRA--RQVIYIAAEALLDENLQLQREKDATEAVALALRD 60 I +QA+RE Y DR + + LQ + A ++ Sbjct: 157 IGEQAVREGNINGPEAYMRFLDREMEGLTAAYNVKLFTEAISSLQIRMNTLTAAKASIEA 216 Query: 61 DM-RQAREQLAAAERRIAELEAKLETADK 88 +AREQ AA +R AE +A+ + A + Sbjct: 217 AAANKAREQAAAEAKRKAEEQARQQAAIR 245
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.9 bits (62), Expect = 0.003 Identities = 11/43 (25%), Positives = 18/43 (41%), Gaps = 3/43 (6%) Query: 1 MNALEKAIQVAGNSSKLAEKLGVSSMTISHWKKRYGGVVPKGR 43 + AL GN K A+ LG++ T+ + G V + Sbjct: 442 LAALTAT---RGNQIKAADLLGLNRNTLRKKIRELGVSVYRSS 481
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 33.0 bits (75), Expect = 5e-04 Identities = 14/62 (22%), Positives = 26/62 (41%), Gaps = 7/62 (11%) Query: 146 VGLAHVKLSNNTIPVGFGINETLSASKNNFAWGAGIGAKYAVTDNIMIDASYKYINAGKV 205 VG+ + K P S F++GAG+ ++ +N+ +D SY+ V Sbjct: 106 VGVGYGKFQTTEYPTYKH-----DTSDYGFSYGAGL--QFNPMENVALDFSYEQSRIRSV 158 Query: 206 SI 207 + Sbjct: 159 DV 160
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 72.2 bits (177), Expect = 5e-15 Identities = 99/652 (15%), Positives = 196/652 (30%), Gaps = 80/652 (12%) Query: 78 PAAERQKALAALSRPLLRNSNLVCGVSEAK-------DSSECGYVATDKEDVAVIFDENN 130 Q + L+R L + G++ A C + + D D Sbjct: 98 TGDSEQGIVPCLTRAQLASM----GLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQ 153 Query: 131 GQLSLFLNRDWLPDEERRDKRWLTPT--PEGVSAF-----IHRQTLYLSDDLHSRNMTLN 183 +L+L + + ++ R + ++ P G++A ++ +S LN Sbjct: 154 QRLNLTIPQAFMS---NRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLN 210 Query: 184 GSGALGLGDGRYLGGNWAAIWNQSEHYNNSQTWFDNLFVRQDLGNQYYLQAGRMDQRNLS 243 L +G R L N +N S+ + S+ + + +L+ R S Sbjct: 211 LQSGLNIGAWR-LRDNTTWSYNSSDSSSGSKNKWQH--------INTWLE--RDIIPLRS 259 Query: 244 SATGGDFGFSLLPLS--RFDGLRTGTTQAYVNHEVDQNATPVMVQVTRNARIDIYRGSEL 301 T GD F G + + + A + A++ I + Sbjct: 260 RLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYD 319 Query: 302 LGSQFLTPGMHTLDTHSLPPGSYPLALRIYEDGILRRTESQPFSKGGNSF-SAQTQWFIQ 360 + + + PG T++ S L + I E + + P+S T++ I Sbjct: 320 IYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSIT 379 Query: 361 GGQEDTGDKASHYDGETVMAAGFRTGLRKNISLTEGISLAHE----AWYSETRLNSQHAV 416 G+ +G+ + + + GL ++ G LA + + + A+ Sbjct: 380 AGEYRSGN--AQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 417 -LDGTLDLSAGILHGTDSTSGNTEQVTYNDGFSASLWRNHTESDACSGRHPQSVHASMTC 475 +D T + L G + + YN + S T R+ S + + Sbjct: 438 SVDMTQ--ANSTLPDDSQHDGQSVRFLYNKSLNES----GTNIQLVGYRYSTSGYFNFAD 491 Query: 476 QTSMNASLSVPVGNWYALLGYSTSRTEGRPVYRGYDDNSDKENVF----------WRQAY 525 T N Y + Y+ +K Y Sbjct: 492 TTYSRM-------NGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLY 544 Query: 526 IPASHRE-------SAQASATYNLNMAGMNINTHGGVWRTRNDGVNDDGLFMSVSVSYAS 578 + SH+ Q A N +N + + D L ++V++ ++ Sbjct: 545 LSGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSH 604 Query: 579 Q-PPTMTGSNGYTSAGTDIHSSRNQKTQTSWNVNHVRSWQQDLYRELSVGFSGYNDDSWS 637 + SA + N + V +L + G++G D + Sbjct: 605 WLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSG 664 Query: 638 GSLGGRMS--GRMGELSATISNSHQRNAGSASSLTAGYSSSLALSRNGLFWG 687 + ++ G G + S+S L G S + NG+ G Sbjct: 665 STGYATLNYRGGYGNANIGYSHS-----DDIKQLYYGVSGGVLAHANGVTLG 711
>PF05775#Enterobacteria AfaD invasin protein Length = 142 Score = 93.8 bits (233), Expect = 2e-27 Identities = 38/132 (28%), Positives = 67/132 (50%), Gaps = 2/132 (1%) Query: 14 SVTLLVAASSLMPIANAAEKLQTTLRVGTYFRAGHVPDGMVLAQGRVTYHGSHSGFRVWS 73 S++L + LM + + ++ TL Y + DG+ LA GR+ +HSGFRVW Sbjct: 4 SISLTLCGILLMLMGSFSQAADITLMNHKYM-GNLLHDGVKLATGRIICQDTHSGFRVWI 62 Query: 74 DEQKAGNTPTVLLLSGQQDPRHHIQVRLEGEGWQPDTVSGRGAILRTAADNAS-FSVVVD 132 + ++ G ++ + P+H++++R+ G GW G + T ++AS F + VD Sbjct: 63 NARQEGGGAGKYIVQSTEGPQHNLRIRISGNGWSSFVEKGIQGVFNTIKEDASIFYIEVD 122 Query: 133 GNQEVPADTWTL 144 GNQ+V + Sbjct: 123 GNQQVQPGKYLF 134
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 823 bits (2127), Expect = 0.0 Identities = 309/872 (35%), Positives = 452/872 (51%), Gaps = 52/872 (5%) Query: 4 KQPALLLFIAGVVHCANA-------HAYTFDASML-GDAAKGVDMSLFNQG-VQQPGTYR 54 K F+ V CA A F+ L D D+S F G PGTYR Sbjct: 20 KHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 55 VDVMVNGKRVDTRDVVFKLEKDGQGTPFLAPCLTVSQLSRYGVKTEDYPQLWKAAKTPDE 114 VD+ +N + TRDV F QG + PCLT +QL+ G+ T + A D Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQG---IVPCLTRAQLASMGLNTASVSGMNLLAD--DA 134 Query: 115 CADL-SAIPQAKAVLDTNNQQLQLSIPQVALRTKFKGIAPEDLWDDGIPAFLMNYSARTT 173 C L S I A A LD Q+L L+IPQ + + +G P +LWD GI A L+NY+ Sbjct: 135 CVPLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGN 194 Query: 174 QTDYKMDMERRDNSSWVQLQPGINIGAWRVRNATSWQR-----SGQQSGKWQAAYTYAER 228 ++ + +++ LQ G+NIGAWR+R+ T+W S KWQ T+ ER Sbjct: 195 SVQNRIG--GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLER 252 Query: 229 GLYSLKSRLTLGQKTSQGEIFDSVPFTGVMLASDDNMVPYSERQFAPVVRGIARTQARVE 288 + L+SRLTLG +QG+IFD + F G LASDDNM+P S+R FAPV+ GIAR A+V Sbjct: 253 DIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVT 312 Query: 289 VKQNGYTIYNTTVAPGPFALRDLSVTDSSGDLHVTVWEADGSTQMFVVPYQTPAIALHQG 348 +KQNGY IYN+TV PGPF + D+ +SGDL VT+ EADGSTQ+F VPY + + +G Sbjct: 313 IKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREG 372 Query: 349 YLKYSLLAGRYRSSDSATDKAQIAQATLMYGLPWNLTAYGGIQSATHYQAALLGLGGSLG 408 + +YS+ AG YRS ++ +K + Q+TL++GLP T YGG Q A Y+A G+G ++G Sbjct: 373 HTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMG 432 Query: 409 RWGSLSVDGSDTHSQRQGEAVQQGASWRLRYSNQLTATGTNLFLTRWQYASQGYNTLSDV 468 G+LSVD + +S ++ G S R Y+ L +GTN+ L ++Y++ GY +D Sbjct: 433 ALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADT 492 Query: 469 LDSYRHNGNRL-------------WSWRENLQPSSRTTLMLSQSWGRHLGNLSLIGSRTD 515 S + N + + L ++Q GR L L GS Sbjct: 493 TYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQT 551 Query: 516 WRNRPGHDDSYGLSWGTSIGVGLLSLNWNQNRTLWRNGEHRKENITSLWFSMPLSRWTGN 575 + D+ + T+ +L+++ + W+ G ++ + +L ++P S W + Sbjct: 552 YWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKG---RDQMLALNVNIPFSHWLRS 608 Query: 576 -------NVSASWQMTSPSHGGQTQQVGVNGEAFSQ-QLDWEVRQSYRADAPPGGGNNSA 627 + SAS+ M+ +G T GV G L + V+ Y G+ Sbjct: 609 DSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGY 668 Query: 628 LHLAWNGDYGLLGGDYSYSRAMRQMGVNIAGGIVIHHHGVTLGQPLQGSVALVEAPGASG 687 L + G YG YS+S ++Q+ ++GG++ H +GVTLGQPL +V LV+APGA Sbjct: 669 ATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKD 728 Query: 688 VPVGGWPGVKTDFRGDTTVGNLSVYQENTVSLDPSRLPDDAEVTQTDVRVVPTEGAVVEA 747 V GV+TD+RG + + Y+EN V+LD + L D+ ++ VVPT GA+V A Sbjct: 729 AKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRA 788 Query: 748 KFHTRIGARALMTLKREDGSAIPFGAQVTVNGQDGSAALVDTDSQVYLTGLADKGELTVK 807 +F R+G + LMTL + +PFGA VT + S+ +V + QVYL+G+ G++ VK Sbjct: 789 EFKARVGIKLLMTLTH-NNKPLPFGAMVT-SESSQSSGIVADNGQVYLSGMPLAGKVQVK 846 Query: 808 WGA---QQCRVNYRLPAHKGIAGLYQMSGLCR 836 WG C NY+LP L Q+S CR Sbjct: 847 WGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 70.3 bits (172), Expect = 2e-15 Identities = 36/128 (28%), Positives = 58/128 (45%), Gaps = 16/128 (12%) Query: 317 QHSRVVFRGDAMFVPGQKTVSDAIRPVINKAAREIARVG---GAVTVTGHTDSQPIHSAE 373 Q + D +F + T+ + +++ +++ + G+V V G+TD I S Sbjct: 211 QTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDA 268 Query: 374 FPSNLVLSEKRAAEVAALLTSGGVPAGRVHIVGKGDTVPVADN---------GSKAGRAK 424 + N LSE+RA V L S G+PA ++ G G++ PV N A Sbjct: 269 Y--NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAP 326 Query: 425 NRRVEILV 432 +RRVEI V Sbjct: 327 DRRVEIEV 334
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.005 Identities = 38/185 (20%), Positives = 58/185 (31%), Gaps = 31/185 (16%) Query: 529 ALREWQGDAPVV----FPEVSAAVVA--AIVADWTGIP--AGRMVKDEASQVLELPARLA 580 +++ + D PV+ A+ A D+ P ++ + E R + Sbjct: 68 RIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPS 127 Query: 581 QRVTGQDGALAQIGE--RIQTAR---AGLGDPRKPVGVFMLAGPSGVGKTETALALAEAI 635 + + +G +Q A L + M+ G SG GK A AL + Sbjct: 128 KLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL---MITGESGTGKELVARALHDYG 184 Query: 636 YGGEQNLVTINMSEFQEAHTVSTLKGAPPGYVGYGEGGVLTEAVRRHPWSV-------VL 688 V INM+ S L G E G T A R + Sbjct: 185 KRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFEQAEGGTLF 236 Query: 689 LDEIE 693 LDEI Sbjct: 237 LDEIG 241
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 46.5 bits (110), Expect = 4e-08 Identities = 32/174 (18%), Positives = 62/174 (35%), Gaps = 9/174 (5%) Query: 23 APRVITLSPANTELAFAAGITPVGVSSYSDY------PPEAQKIEQVSTWQGMNLERIVA 76 R++ L EL A GI P GV+ +Y PP + V NLE + Sbjct: 35 PNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTE 94 Query: 77 LKPDLVVAWRG-GNAERQVNQLTSLGIKVMWVDAVSIEQIADTLRQLAAWSPQPEKAQQA 135 +KP +V G G + + ++ + +L ++A A+ Sbjct: 95 MKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETH 154 Query: 136 AQTLLNEYAALNAEYAGKAKKRVFLQFGMNP--LFTSGKGSIQHQVLTTCGGEN 187 + ++ + + + + L ++P + G S+ ++L G N Sbjct: 155 LAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPN 208
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 498 bits (1283), Expect = 0.0 Identities = 245/296 (82%), Positives = 266/296 (89%) Query: 1 MRDLYPLTRRRLLTAMALSPLLWQMNTAQAAAIDPRRIVALEWLPVELLLALGITPYGVA 60 M L ++RRRLLTAMALSPLLWQMNTA AAAIDP RIVALEWLPVELLLALGI PYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DVPNYKLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEKLARIAPGR 120 D NY+LWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPE LARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFDFSDGKKPLAVARRSLVELAQTLNLEATAEKHLAQYDRFIASQKPHFIRRGGRPLLMT 180 GF+FSDGK+PLA+AR+SL E+A LNL++ AE HLAQY+ FI S KP F++RG RPLL+T Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVLGPNCLFQEVLDEYGIVNAWQGETNFWGSTAVSIDRLAMYKEADVICFDH 240 TLIDPRHMLV GPN LFQE+LDEYGI NAWQGETNFWGSTAVSIDRLA YK+ DV+CFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 GNSTDMNALMATPLWQAMPFVRAGRFHRVPAVWFYGATLSTMHFVRILNNVLGGKA 296 NS DM+ALMATPLWQAMPFVRAGRF RVPAVWFYGATLS MHFVR+L+N +GGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/141 (14%), Positives = 50/141 (35%), Gaps = 1/141 (0%) Query: 343 VPYPNNTVAQRFHPTNVSGGLSATQQAPVSRDSQRQAAMAQFQQRSHTSPANLSGETSRD 402 + PNN A + + ++ +APV + + + + S + Sbjct: 997 ITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPS-ETTETVAENSKQESKTVEKNE 1055 Query: 403 RQRKAASQQLNQIAQRNNYRGYDGTQNSSRREAAQQTLNKSTTQQHRSELKAKAQQHPVS 462 + + Q ++A+ TQ + ++ +T TT+ + K ++ V Sbjct: 1056 QDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVE 1115 Query: 463 QQQRDTARQRIESSTPQQRQA 483 ++ + +P+Q Q+ Sbjct: 1116 TEKTQEVPKVTSQVSPKQEQS 1136
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.3 bits (84), Expect = 4e-04 Identities = 43/282 (15%), Positives = 85/282 (30%), Gaps = 38/282 (13%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGVVKEIKVSVGDKTETGALIMIFDSADGAADAAP 85 + V +T G S E+ + +VKEI V G+ G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AKA--------EEKKEAAPAAAPAAAAAKDVHVPDIGSDEVEVTEVMVKVG------DTV 131 ++ + + + + + + V EV+ T Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 132 EAEQSLITVEGDKASMEVPAPFAGTVKEIKVNTGDKVSTGSLIMVFEVAGAAPAKAEAAP 191 + ++ + DK E A + ++ +K + A K Sbjct: 199 QNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHK-QAIA-KHAVLE 256 Query: 192 AAAAPAAATGVKDVNVPDIGGDEVEVTEVMVK-----------VGDKVA--------AEQ 232 A V + E E+ + + DK+ Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTL 316 Query: 233 SLITVEGDKASMEVPAPFAGTVKEIKIST-GDKVKTGSLIMV 273 L E + + + AP + V+++K+ T G V T +MV Sbjct: 317 ELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.8 bits (67), Expect = 0.039 Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 4/85 (4%) Query: 226 DKVAAEQSLITVEGDKASMEVPAPFAGTVKEIKISTGDKVKTGSLIMVFEVEGAAPAAAP 285 + VA +T G S E+ VKEI + G+ V+ G ++ ++ A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVL--LKLTALGAEADT 136 Query: 286 AKQEAAAPAPAAKAEKPAAPAAKAE 310 K +++ + + + E Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIE 161
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.014 Identities = 16/79 (20%), Positives = 27/79 (34%), Gaps = 3/79 (3%) Query: 4 RRQPLIPGWLIPGLCAAALMITVALAAFLALWLNAPSGAWSTIWRDSYLWHVVRFSFWQA 63 R GWL + L + A +W A + W + +++ Sbjct: 60 RSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLL---AFINTKPVAFTLPL 116 Query: 64 FLSAVLSVVPAVFLARALY 82 LS + +VV F+ LY Sbjct: 117 ALSIIFNVVVVTFMWSLLY 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.008 Identities = 20/110 (18%), Positives = 38/110 (34%), Gaps = 18/110 (16%) Query: 34 CKALREEGYRVILVNS-----------NPATIMTDPEMADATYIEPIHWEVVRKIIEKER 82 +AL GY V + ++ + ++TD M D + + I+K R Sbjct: 20 NQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD------LLPRIKKAR 73 Query: 83 PDAVLPTMGGQTALNCALELERQGVLEEFGVTM-IGATADAIDKAEDRRR 131 PD + M Q A++ +G + + I +A + Sbjct: 74 PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 38.3 bits (89), Expect = 1e-05 Identities = 21/102 (20%), Positives = 43/102 (42%), Gaps = 4/102 (3%) Query: 154 NPFTLGHRYLVEQAAAACDWLHLFVVKEDAS--FFSYTDRWALIEQGIAGIDNVTLHSGS 211 +P T GH ++E+ D +++ V++ FS +R I + IA + N + S Sbjct: 10 DPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIAHLPNAQVDSFE 69 Query: 212 AYMISRATFPGYFLKEKGV--VDDCHCQIDLQLFREHLAPAL 251 ++ A +G+ + D ++ + + LA L Sbjct: 70 GLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDL 111
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 141 bits (357), Expect = 3e-39 Identities = 84/388 (21%), Positives = 152/388 (39%), Gaps = 86/388 (22%) Query: 5 IGIDLGTTNSCVAIMDGTQARVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58 + IDLGT N+ + + Q VL PS++A QD VG AK+ Sbjct: 13 LSIDLGTANTLIYVKG--QGIVLNE-------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPYKIIGADNGDAWLDVKGQKMAPPQISAE 118 P N + AI+ +K +A ++ + Sbjct: 64 GRTPGN-IAAIR---------------------------------PMKDGVIADFFVTEK 89 Query: 119 VLKK-MKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAAL 177 +L+ +K+ + P ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 90 MLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAI 149 Query: 178 AYGL--DKEVGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDTR 235 GL + G+ V D+GGGT ++++I ++ V + +GG+ FD Sbjct: 150 GAGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEA 197 Query: 236 LINYLVDEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADAT 291 +INY+ + G + AE+ K E+ SA + ++ + Sbjct: 198 IINYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEG 244 Query: 292 GPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIND--VILVGGQTRMPM 348 P+ + + LE+L E + + + VAL+ SDI++ ++L GG + Sbjct: 245 VPRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRN 302 Query: 349 VQKKVAEFFGKEPRKDVNPDEAVAIGAA 376 + + + E G +P VA G Sbjct: 303 LDRLLMEETGIPVVVAEDPLTCVARGGG 330
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 770 bits (1989), Expect = 0.0 Identities = 335/877 (38%), Positives = 491/877 (55%), Gaps = 70/877 (7%) Query: 14 LSFLFICCS----IKPALAHDHFNPLSLENDEPGVENVDLSVFEKGGQAE-GTYNVDIYI 68 LF+ C+ + A +FNP L +D DLS FE G + GTY VDIY+ Sbjct: 27 FVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 69 NNASVETKNIAFKNKKSADNKLSLQPCLSVAQLKQWGVKTENFPELQN-DPNGCTDL-SL 126 NN + T+++ F + D++ + PCL+ AQL G+ T + + + C L S+ Sbjct: 85 NNGYMATRDVTFN---TGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSM 141 Query: 127 LAGAVAKFNVIGNRLDLAIPQIALIADPREFVPTSEWDEGINAFLLNYSFTGSQDHDIDE 186 + A A+ +V RL+L IPQ + R ++P WD GINA LLNY+F+G+ + Sbjct: 142 IHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN-RI 200 Query: 187 NRTENSEYANLRPGINIGAWRFRNYSTW-----NHDSDGQNSWDSAYTYVSRDIEFLKGQ 241 + Y NL+ G+NIGAWR R+ +TW + S +N W T++ RDI L+ + Sbjct: 201 GGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSR 260 Query: 242 LIAGENNTPADVFDSISFKGVQISSDDDMLPDSMKGFAPVIRGVAKSSAQVTVEQNGYTI 301 L G+ T D+FD I+F+G Q++SDD+MLPDS +GFAPVI G+A+ +AQVT++QNGY I Sbjct: 261 LTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDI 320 Query: 302 YKTNVPAGPFAINDLYPTGGSGDLYVTIKESDGSEQHFIVPYASVPVLQREGHLKYDLTV 361 Y + VP GPF IND+Y G SGDL VTIKE+DGS Q F VPY+SVP+LQREGH +Y +T Sbjct: 321 YNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITA 380 Query: 362 GRTRSSDSHSAQQNFAELTALYGLAGGITAYGGIESTLSNDIYHAALIGTGLNLGDLGAL 421 G RS ++ + F + T L+GL G T YGG + D Y A G G N+G LGAL Sbjct: 381 GEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLA---DRYRAFNFGIGKNMGALGAL 437 Query: 422 SLDVTNSWSKIKAGDVVSDTLTGQSWRIRYSKDIQSTGTNFTVAGYRYSTKDYYALEDVL 481 S+D+T + S + GQS R Y+K + +GTN + GYRYST Y+ D Sbjct: 438 SVDMTQANSTLPDD----SQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTT 493 Query: 482 DTYSD--------------------NSHYDHVRNRTDLSLSQDII-YGSISLTLYNEDYW 520 + + + + R + L+++Q + ++ L+ ++ YW Sbjct: 494 YSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYW 553 Query: 521 N-DTHTTSLGIGYNNTWHNVSYGINYSYTLNADNSQDEDDDTEDSNDQQISINISIPLDA 579 G N + ++++ ++YS T NA DQ +++N++IP Sbjct: 554 GTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKG---------RDQMLALNVNIPFSH 604 Query: 580 FMPS--------TYATYNMNSAKDGDTTHTVGLNGTALAQKNLSWSVQEGYSS---QEKA 628 ++ S A+Y+M+ +G T+ G+ GT L NLS+SVQ GY+ Sbjct: 605 WLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSG 664 Query: 629 TSGNVSATYNGTYADINGGYSYDNHMRRLNYGVQGGVLLHRNGLTLSQPMDDTIILVKAP 688 ++G + Y G Y + N GYS+ + +++L YGV GGVL H NG+TL QP++DT++LVKAP Sbjct: 665 STGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAP 724 Query: 689 GAAGVPVNNETGVDTDFRGYAVVPYASPYHRNEVSLDTTGIRKNIELIDTSKTLVPTRGA 748 GA V N+TGV TD+RGYAV+PYA+ Y N V+LDT + N++L + +VPTRGA Sbjct: 725 GAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGA 784 Query: 749 VVRAEYKTNIGYKALMALTRINNLPVPFGATVSSLTKPDNHSSFVGDAGQAWLTGLEKQG 808 +VRAE+K +G K LM LT NN P+PFGA V+S + S V D GQ +L+G+ G Sbjct: 785 IVRAEFKARVGIKLLMTLTH-NNKPLPFGAMVTSES--SQSSGIVADNGQVYLSGMPLAG 841 Query: 809 RLLVKWGPTAADQCQVSYRIPSSPSASGVEILHEQCQ 845 ++ VKWG C +Y++P + L +C+ Sbjct: 842 KVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.6 bits (230), Expect = 6e-24 Identities = 32/139 (23%), Positives = 58/139 (41%) Query: 1 MQQPQVWLVEDEQGIADTLIYTLQLEGFTVELFARGLPALEKARQQRPDAVILDVGLPDI 60 M + + +D+ I L L G+ V + + D V+ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLERHPALPILFLTARSDEVDRLLGLEIGADDYVAKPFSPREVSARVRTLLR 120 + F+L ++ + P LP+L ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFAAPSPVVRTGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 33.6 bits (77), Expect = 7e-04 Identities = 15/73 (20%), Positives = 35/73 (47%), Gaps = 10/73 (13%) Query: 71 GKFYPLHTGHIYLIQRACSQVDELHIIMGYDDTRDRGLFEDSAMSQQPTVSDRLRWLLQT 130 G F P+ GH+ +I+R C D++++ + + + +F +V +RL + + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVL-RNPNKQPMF---------SVQERLEQIAKA 56 Query: 131 FKYQKNIRIHAFN 143 + N ++ +F Sbjct: 57 IAHLPNAQVDSFE 69
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 26.3 bits (58), Expect = 0.048 Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 1/57 (1%) Query: 61 IIALTDIFAGSVNNEFVRYLS-RENFHLLAGINLPLVIDLFMSENDGNTTHTIMTAL 116 + AL I S+N+ V + REN + L V++L ++E T T MT L Sbjct: 209 VAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSRTVMTGMTTL 265
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 171 bits (436), Expect = 4e-48 Identities = 91/381 (23%), Positives = 157/381 (41%), Gaps = 52/381 (13%) Query: 106 LIGHNESLKRPIEQLKTALFYPDGGLPLLMTGESGTGKSYLAQLMHEYAIAQALLSP--D 163 L+G + +++ L + L L++TGESGTGK +A+ +H+ + Sbjct: 139 LVGRSAAMQEIYRVLARLM---QTDLTLMITGESGTGKELVARALHD-------YGKRRN 188 Query: 164 APFISFNCAQYASNPELLAANLFGYVKGAFTGAQSDRPGAFEAADGGMLFLDEVHRLSAE 223 PF++ N A A +L+ + LFG+ KGAFTGAQ+ G FE A+GG LFLDE+ + + Sbjct: 189 GPFVAINMA--AIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMD 246 Query: 224 GQEKLFTWLDRGEIYRVGDTAQGHPVSVRLVFATT----EEIHS-TFLTTFLRRI-PIQV 277 Q +L L +GE VG VR+V AT + I+ F R+ + + Sbjct: 247 AQTRLLRVLQQGEYTTVGGR-TPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 278 NLPDLQHRSRQEKEALILLFFWTEAKKLS-ATLILKPRLLQILNQYVYRGNVGELKNVVK 336 LP L R R E ++ F +A+K L+++ + + GNV EL+N+V+ Sbjct: 306 RLPPL--RDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLVR 363 Query: 337 YAVATAWAKKPGQETVTVSLHDLPDAMLSALPSLNESLADDTPVSISPDTNLTWLLRARD 396 A ++ + + + S +P A S+S + +R Sbjct: 364 RLTALY-------PQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 397 EMQG-MIHDTQCHVLALYELVRSGKEGWETVQKRMGDEIEALFDRLIFTGDDNVHSQRLL 455 G + + + L E+ E + L T + + + LL Sbjct: 417 ASFGDALPPSGLYDRVLAEM-----------------EYPLILAALTATRGNQIKAADLL 459 Query: 456 LITSQVREEFYRLEKRFNMQL 476 + R + + + + Sbjct: 460 GLN---RNTLRKKIRELGVSV 477
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.017 Identities = 8/21 (38%), Positives = 14/21 (66%) Query: 30 ESNVLITGPNGCGKSTLLRAI 50 + ++ITG +G GK + RA+ Sbjct: 160 DLTLMITGESGTGKELVARAL 180
>cloacin#Cloacin signature. Length = 551 Score = 30.8 bits (69), Expect = 0.004 Identities = 37/147 (25%), Positives = 58/147 (39%), Gaps = 20/147 (13%) Query: 54 ARVKLSHDKLNDLRERKASLETRALAAMSKNVDAAL--LNEVAEEIARLENAILAEEQVL 111 +VK D+ N R ++ T + A +N + A LN+ E++AR + QV Sbjct: 294 DQVKQRQDEEN--RRQQEWDATHPVEAAERNYERARAELNQANEDVARNQERQAKAVQVY 351 Query: 112 TNLEASRDAVEKAVTATGQRIAQFEQQLEVVKATEAMQRAQQAVTTSTVGAASNVSTAAE 171 + ++ DA K + I QF + A + M G A Sbjct: 352 NSRKSELDAANKTLADAIAEIKQFNRF-----AHDPM-----------AGGHRMWQMAGL 395 Query: 172 SLKRLQTRQAERQARLDAAAQLEKVAD 198 +R QT +QA DAAA+ + AD Sbjct: 396 KAQRAQTDVNNKQAAFDAAAKEKSDAD 422
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.013 Identities = 12/55 (21%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 165 VVPDDSRLSFDILIPPEDVMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 218 +VP+D L L+ +D+ +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 29.0 bits (64), Expect = 0.030 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 3/65 (4%) Query: 225 NRMRAEREAVARRHRSQGQEEAEKLRAAADYEVTK---TLAEAERQGRIMRGEGDAEAAK 281 N+ R + A A+R + + +RAA Y + +A A +G I +G A A+ Sbjct: 220 NKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQ 279 Query: 282 LFADA 286 +DA Sbjct: 280 AISDA 284
>SECA#SecA protein signature. Length = 901 Score = 33.3 bits (76), Expect = 0.002 Identities = 26/144 (18%), Positives = 55/144 (38%), Gaps = 6/144 (4%) Query: 282 HVVDAADVRVQENIEAVNTVLEEIDAHEIPTLMVMNKIDMLDDFEPRIDRDEENK-PIRV 340 ++D +DV N + IDA+ P + ++ + + R+ D + PI Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQSGVGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIEY 424 +R I R +++P EY Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 30.1 bits (68), Expect = 0.028 Identities = 26/161 (16%), Positives = 57/161 (35%), Gaps = 18/161 (11%) Query: 31 VENSLDAGATRVDIDIER---GGAKLIR-IRDNGCGIKKEELALALARHATSKIASLDDL 86 ++ SLD A + ++ I R A++ ++ N G E + A+ + +L++ Sbjct: 5 IQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLNLEEA 64 Query: 87 EAIISLGFRGEAL----------ASISSVSRLTLTSRTAEQAEAWQAYAEGRDMDVTVK- 135 + G++G L I RLT + Q +A Q +D+ +K Sbjct: 65 ITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKV 124 Query: 136 -PAAHPVGTTLEVLDLFYNTPARRKFMRTEK--TEFNHIDE 173 + +G + + + + + F + Sbjct: 125 NSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEH 165
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.5 bits (110), Expect = 9e-09 Identities = 28/189 (14%), Positives = 54/189 (28%), Gaps = 15/189 (7%) Query: 3 REDILGEALKLLETQGIADTTLEMVAERVNRPLDTLQRFWPDKEAILYDALRYLSQQVDI 62 R+ IL AL+L QG++ T+L +A+ + + DK + + + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 63 WRRQLLLDETLSAEQKLLARYSA-LSECVSNNRYPGCLFIAACTFYPDPTHPIHQLANQQ 121 + L L V+ R + F+ + Q Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRL---LMEIIFHKCEFVGEMAVVQQA 129 Query: 122 KRTAHDFTHELLTTL--------EID---DPAMVARQMELVLEGCLSRMLVNRSQADVDT 170 +R +++ + + A M + G + L D+ Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKK 189 Query: 171 AQRLAEDIL 179 R IL Sbjct: 190 EARDYVAIL 198
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 393 bits (1012), Expect = e-126 Identities = 200/864 (23%), Positives = 330/864 (38%), Gaps = 88/864 (10%) Query: 20 LALAIAVALGSGTASAGEKLDMSFIQGGAGINPEVWAALNGDY-APGRYLVDLSLNGKDI 78 L +A A A + +SA + F+ ++ NG PG Y VD+ LN + Sbjct: 30 LFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 79 GKRILDVTPQDSEA---LCLSEAWLAKAGIYVSAEYFRKGYDAMRQCWVLAKA-PAVKVD 134 R + DSE CL+ A LA G+ ++ A C L Sbjct: 90 ATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTAS-VSGMNLLADDACVPLTSMIHDATAQ 148 Query: 135 FDVATQSLSLAIPQKGLVKMPENV----EWDYGTEAFRMNYNANANSGRYN---TSAFGS 187 DV Q L+L IPQ + WD G A +NYN + NS + S + Sbjct: 149 LDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAY 208 Query: 188 ADLKA--NIGRWVVSSSATASTGDGGSNEATINMFT-----ATRAIRSLSADLAVGKTST 240 +L++ NIG W + + T S S+ + N + R I L + L +G T Sbjct: 209 LNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYT 268 Query: 241 GDSLLGSTGTYGVSLSRNNSMKPGSL-GYTPVFSGIANGPSRVTLTQNGRMLYSGMMPSG 299 + G L+ +++M P S G+ PV GIA G ++VT+ QNG +Y+ +P G Sbjct: 269 QGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPG 328 Query: 300 PFSVTDVPLYS-SGDVTMTVTGDDGREQTQVFPLSVMAGQLSPGQHEFSVAAGIPDDDSD 358 PF++ D+ SGD+ +T+ DG Q P S + G +S+ AG + Sbjct: 329 PFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNA 388 Query: 359 LEGG--VFAASYGYGL-DGLTLRTGGVFNQDWQGASAGAVLGLGYLGALSADGAYATAK- 414 + F ++ +GL G T+ G ++ + G +G LGALS D A + Sbjct: 389 QQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTL 448 Query: 415 YRDGSRSGNKVKLAWSKQLALTNTGLR-VSWSHQSEEYEDMSSF---------------- 457 D G V+ ++K L + T ++ V + + + Y + + Sbjct: 449 PDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGV 508 Query: 458 --NPAETWLQQNQGRRTRDEWNAGISQPVGGLFSLSASGWQRSYYPASTTGSYRYADDNG 515 + N R + ++Q +G +L SG ++Y+ + Sbjct: 509 IQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYW-----------GTSN 557 Query: 516 KETGITGTLSTQIKSVSLNLGWSGSRNMNGENTW-SASASVSVPF--------TLFERKY 566 + L+T + ++ L +S ++N + + +V++PF R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 567 SSSTTVSTGKDGGTGVSTGISGAL--NDRFSYGLGGGRDSDGGISS----YLNAAYSGDR 620 S+S ++S +G G+ G L ++ SY + G G +S Y Y G Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 621 ANLNGTVNHSSGSGTSGSVSASGSVLAVPAARDIMFSRTTGDTVAVVSVKDTPGVKVMSG 680 N N +HS SG VLA + + DTV +V KV + Sbjct: 678 GNANIGYSHSDDI-KQLYYGVSGGVLAHANG--VTLGQPLNDTVVLVKAPGAKDAKVENQ 734 Query: 681 NETS-DSDGNLVVP-LNSYDWNTVTIDAGTLPLDTELSTTSRKVVPTDSAVVWMPFDALK 738 D G V+P Y N V +D TL + +L VVPT A+V F A Sbjct: 735 TGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARV 794 Query: 739 VHRYLLQVRMPDGAFVPGGTWARDSNNTPLGFVANNGVLMINAVDRPGDITL-------G 791 + L+ + + +P G ++ G VA+NG + ++ + G + + Sbjct: 795 GIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENA 853 Query: 792 QCRI----PAAKLQETAKLQEITC 811 C P Q+ C Sbjct: 854 HCVANYQLPPESQQQLLTQLSAEC 877
>FIMREGULATRY#Escherichia coli: P pili regulatory PapB protein signature. Length = 104 Score = 103 bits (257), Expect = 2e-32 Identities = 39/80 (48%), Positives = 58/80 (72%) Query: 14 VRAGELEPGAVSEEQFWLLVDISPIHSEKIILALKDYFVSGYSRKVVCERHGMSGGYLST 73 +R L PG++SE F+LL+ IS IHS+++ILA+KDY V G+SRK VCE++ M+ GY ST Sbjct: 18 IRESVLLPGSMSEMHFFLLIGISSIHSDRVILAMKDYLVGGHSRKEVCEKYQMNNGYFST 77 Query: 74 SVNRLNFISRNVHKLAGYYS 93 ++ RL ++ +LA YY+ Sbjct: 78 TLGRLIRLNALAARLAPYYT 97
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.5 bits (71), Expect = 0.001 Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 6/65 (9%) Query: 89 LAVDKSLHGQGVGRALVRDAGLRVIQVAETIGIRGMLVHALSDE--AREFYQRVGFVPSP 146 +AV K +GVG AL+ A I+ A+ G+++ A FY + F+ Sbjct: 95 IAVAKDYRKKGVGTALLHKA----IEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150 Query: 147 MDPMM 151 +D M+ Sbjct: 151 VDTML 155
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.1 bits (119), Expect = 2e-07 Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 30/190 (15%) Query: 96 DSAQVEKKGNGKRRNKKEEEELKKQLDEAENAKK--EADKAK-EEAEKAKEAAEKALNEA 152 A+ + + + L++ LD + AKK EA+ K EE K EA+ ++L Sbjct: 293 LEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 352 Query: 153 FEVQNSSK-QIEEMLQNFLADNVAKDNLAQQSDASQQNTQA---KATQASKQNDAEKVLP 208 + +K Q+E Q N + S+AS+Q+ + + +A KQ + Sbjct: 353 LDASREAKKQLEAEHQKLEEQN-------KISEASRQSLRRDLDASREAKKQVEKALEEA 405 Query: 209 QPI-------NKNTSTGK--SNSSKNEEN-KLDAESVKEPLKVTLALAAES----NSGSK 254 NK K + K E KL+AE+ + LK LA AE +G Sbjct: 406 NSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEA--KALKEKLAKQAEELAKLRAGKA 463 Query: 255 DDSITNFTKP 264 DS T KP Sbjct: 464 SDSQTPDAKP 473 Score = 48.1 bits (114), Expect = 9e-07 Identities = 35/136 (25%), Positives = 63/136 (46%), Gaps = 4/136 (2%) Query: 98 AQVEKKGNGKRRNKKEEEELKKQLDEAENAKKEADKAKEEAEKAKEAAEKALNEAFEVQN 157 A+ +K + ++ + L++ LD + AKK+ +KA EEA A EK E E + Sbjct: 365 AEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKK 424 Query: 158 SSKQIEEMLQNFL-ADNVA-KDNLAQQSD--ASQQNTQAKATQASKQNDAEKVLPQPINK 213 +++ + LQ L A+ A K+ LA+Q++ A + +A +Q K +P Sbjct: 425 LTEKEKAELQAKLEAEAKALKEKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQA 484 Query: 214 NTSTGKSNSSKNEENK 229 + K N +K + Sbjct: 485 PQAGTKPNQNKAPMKE 500 Score = 43.9 bits (103), Expect = 2e-05 Identities = 17/115 (14%), Positives = 41/115 (35%), Gaps = 19/115 (16%) Query: 101 EKKGNGKRRNKKEEEELKKQLDEAENAKKEAD-------KAKEEAEKAKEAAEKALNEAF 153 ++ ++ + + + + E + + + A ++L Sbjct: 260 ARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQ-SQVLNANRQSLRRDL 318 Query: 154 EVQNSSK-QIEEMLQNFLADNVAKDNLAQQSDASQQNTQAK---ATQASKQNDAE 204 + +K Q+E Q N + S+AS+Q+ + + +A KQ +AE Sbjct: 319 DASREAKKQLEAEHQKLEEQN-------KISEASRQSLRRDLDASREAKKQLEAE 366
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 266 bits (682), Expect = 8e-87 Identities = 87/425 (20%), Positives = 175/425 (41%), Gaps = 25/425 (5%) Query: 9 LMMIIISLTILIIILTYFIEINSVVHGQGVITTKDNAQLISLSKGGTIQDIYVAEGDTVK 68 + I+ ++ IL+ ++ V G +T ++ I + +++I V EG++V+ Sbjct: 60 VAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVR 119 Query: 69 KGELLAKVVNLDLQKEYQRYRTQKGYLDKDVNEI-------SFILDKENESGLITLDGTR 121 KG++L K+ L E +TQ L + + S L+K E L + Sbjct: 120 KGDVLLKLT--ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQ 177 Query: 122 SLSNKEVKANIELVHSQIRA-------KELKKTSLDSEISGLQEKLSSKEKELALLAEEI 174 ++S +EV L+ Q KEL +E + +++ E + + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 175 NILSPLVKKGISPYTNFLNKKQAYIKVKSEINDIESSITLKKDDIELVVNDIEALNNELR 234 + S L+ K L ++ Y++ +E+ +S + + +I + + + + Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 235 LSLSKIISKNLQELEVVNSTLKVIEKQINEEDIYSPVDGVIYKINKSATTHGGVIQAADL 294 + + + + ++ L E++ I +PV + ++ T GGV+ A+ Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQL--KVHTEGGVVTTAET 355 Query: 295 LFEIKPKVRTMLADVKILPKYRDQIYVDEAVKLDVQSIIQPKIKSYNATIDNISPDSYEE 354 L I P+ T+ + K I V + + V++ + + NI+ D+ E+ Sbjct: 356 LMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIED 415 Query: 355 NTGGTIQRYYKVIIAFDVNE----DDLRWLKPGMTVDASVITGKHSIMEYLLSPLMKGVD 410 G + VII+ + N + L GM V A + TG S++ YLLSPL + V Sbjct: 416 QRLGL---VFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVT 472 Query: 411 KAFSE 415 ++ E Sbjct: 473 ESLRE 477
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 2e-24 Identities = 36/128 (28%), Positives = 64/128 (50%), Gaps = 2/128 (1%) Query: 3 KILLVDDDRELTSLLKELLEMEGFNVLVAHDGEQALELL-DDSIDLLLLDVMMPKKNGID 61 IL+ DDD + ++L + L G++V + + + DL++ DV+MP +N D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 TLKALRQTH-QTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSHW 120 L +++ PV++++A+ + + + E GA DYLPKPF+ EL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 SEQQQSSD 128 + D Sbjct: 125 RPSKLEDD 132
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.037 Identities = 19/108 (17%), Positives = 37/108 (34%), Gaps = 28/108 (25%) Query: 354 LENIVRNALRY------SHTKIEVGFSVDKDGITITVDDDGPGVSPEDREQIFRPFYRTD 407 ++ +V N +++ KI + + D +T+ V++ G +E Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE---------- 309 Query: 408 EARDRESGGTGLGLAIVESAMQQHRGWVKAD---DSPLGGLRLTLWLP 452 TG GL V +Q G +A G + + +P Sbjct: 310 --------STGTGLQNVRERLQMLYG-TEAQIKLSEKQGKVNAMVLIP 348
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 26.7 bits (58), Expect = 0.043 Identities = 15/42 (35%), Positives = 21/42 (50%) Query: 70 AEAQVIIEQANKRRAQILDEAKTEAEQERTKIVAQAQAEIEA 111 A+A + ANK R Q EAK +AE++ + A A A Sbjct: 210 AKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYA 251
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.1 bits (112), Expect = 8e-08 Identities = 65/384 (16%), Positives = 118/384 (30%), Gaps = 36/384 (9%) Query: 66 AEMGYVFSAFAWLYTLCQIPGGWFLDRIGSRLTYFIAIFGWSVATLLQGFATGLLSLIGL 125 A G + + +A + C G DR G R +++ G +V + A L L Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 126 RAITGIFEAPAFPANNRMVTSWFPEHERASAVGFYTSGQFVGLAFLTPLLIWIQEMLSWH 185 R + GI A + ERA GF ++ G+ P+L + S H Sbjct: 103 RIVAGITGAT-GAVAGAYIADITDGDERARHFGFMSACFGFGMV-AGPVLGGLMGGFSPH 160 Query: 186 WVFIVTGGIGIIWSLVWFKVYQPPRLTKSLSQAELEYIRDGGGLVDGDAPAKKEARQPLT 245 F + + L + + P ++EA PL Sbjct: 161 APFFAAAALNGLNFLTGCFLLPESHKGE-------------------RRPLRREALNPLA 201 Query: 246 KADWKLVFHRKLVGVYLGQFAVNSTLWFFLTWFPNYLTQEKGITALKAGFMTTV-PFLAA 304 W + + F + + + A G L + Sbjct: 202 SFRWARGM-TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHS 260 Query: 305 FFGVLLSGWLADKLVKKGFSLGVARKTPIICGLLISTC--IMGANYTNDPLWIMALMAIA 362 +++G +A +L + ++ G++ I+ A T + ++ +A Sbjct: 261 LAQAMITGPVAARL---------GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLA 311 Query: 363 FFGNGFASITWSLISSLAPMRLIGLTGGMFNFIGGLGGISVPLVIGYL-AQSYGFAPALV 421 G G ++ +++S G G + L I PL+ + A S Sbjct: 312 SGGIGMPALQ-AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWA 370 Query: 422 YISVVALLGALSYILLVGDVKRVG 445 +I+ AL L G G Sbjct: 371 WIAGAALYLLCLPALRRGLWSGAG 394
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 6e-10 Identities = 28/162 (17%), Positives = 64/162 (39%), Gaps = 5/162 (3%) Query: 681 RLLLIEDNMLTQRITAEMLTGKGVKVSVAESANDALRCLAEGESFDVALVDFDLPDYDGL 740 +L+ +D+ + + + L+ G V + +A R +A G+ D+ + D +PD + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDENAF 63 Query: 741 TLAQQLMSLYPAMKRIGFSAH-VIDDNLRQRTAGLFCGIIQKPVPREELYRMIAHYLQGK 799 L ++ P + + SA ++ G + + KP EL +I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAY-DYLPKPFDLTELIGIIGRALAEP 122 Query: 800 SHNARAMLNEHQLAGDMASVGP--EKLRQWVALFKDSALPLV 839 + ++ Q + +++ + +A + L L+ Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLM 164
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 1/115 (0%) Query: 4 HIVIVEDEPVTQARLQAYFEQEGYRVSVTDSGAGLRDIMEHEHVSLILLDINLPDENGLM 63 I++ +D+ + L + GY V +T + A L + L++ D+ +PDEN Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 LTRALRER-STVGIILVTGRCDQIDRIVGLEMGADDYVTKPLELRELVVRVKNLL 117 L +++ + +++++ + + I E GA DY+ KP +L EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 41.0 bits (96), Expect = 8e-06 Identities = 72/408 (17%), Positives = 138/408 (33%), Gaps = 60/408 (14%) Query: 29 RHILITIWLGYALFY--FTRKSFNAAAPEILASGILTRSDIGLLATLFYITYGVSKFVSG 86 RH I IWL F+ N + P+I + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSNARYFMGIGLIATGIVNILFGFSTSLWAFALLWALNAFFQGFGS---PVCARLL 143 +SD+ + + G+I +++ S F L + F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPLVMAAVALHYGWRVGMMVAGLLAIGVGMVLC 202 A Y + RG + L + +G + P + +A + W +++ + I V Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITV----- 182 Query: 203 WRLRDRPQAIGLPPVGDWRHDALEVAQQQEGAGLSRKEILAKYVLLNPYIWLLSLCYVLV 262 P + L ++ G L I+ + Y + VL Sbjct: 183 ------PFLMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVSMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNG----------------NRGPMNLIFAAGILLSVGSL---WLMPFASYVMQ 347 GS +F G RGP+ ++ LSV L +L+ S+ M Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMT 352 Query: 348 AACFFTTGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLGASL 395 F G F + +I + ++ AGA + ++L Sbjct: 353 IIIVFVLGGLSF-TKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 36.0 bits (83), Expect = 3e-04 Identities = 27/168 (16%), Positives = 64/168 (38%), Gaps = 16/168 (9%) Query: 49 FNIAQNDMISTYGLSMTELGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--- 89 Query: 109 MLGFSASMGAGSTSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 F + +G S F ++ + F Q G + + + ++ P+ RG G Sbjct: 90 --CFGSVIGFVGHSFFSLLIM---ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRF 212 +G + A+Y+ + + + P +I +I ++ Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP-MITIITVPFLMKL 188
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.7 bits (85), Expect = 1e-04 Identities = 40/208 (19%), Positives = 77/208 (37%), Gaps = 13/208 (6%) Query: 33 ITVEFLPVSLLTP----MAQDLGISEGVAGQSVTVTAFVAMFSSLFITQIIQATDR--RY 86 + ++ + + L+ P + +DL S V + A A+ + +DR R Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 87 IVILFAVLLTA-SCLMVSFANSFTLLLLGRACLGLALGGFWAMSASLTMRLVPARTVPKA 145 V+L ++ A +++ A +L +GR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 146 LSVIFGAVSIALVIAAPLGSFLGGIIGWRNVFNAAAVMGVLCVIWVVKSLP-SLPGEPSH 204 + +V LG +GG F AAA + L + LP S GE Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 205 QKQ---NMFSLLQRPGVMAGMIAIFMSF 229 ++ N + + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.2 bits (70), Expect = 0.012 Identities = 15/114 (13%), Positives = 34/114 (29%), Gaps = 2/114 (1%) Query: 17 DKEQKQEQTEEQQIVEEQRPVEPPVETAADIDAQTPAHSKAETEAFAEEVVDVTEKVQES 76 +++ K E + Q++ + V P E + + Q + + +E T ++ Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT 1168 Query: 77 EKP-QPVEPEPATAVETAAPQIAVEREELPLPEEVKDEAISPEEWQAEAETVEV 129 E+P + V + PE P + + Sbjct: 1169 EQPAKETSSNVEQPVTESTTVNTGNSVV-ENPENTTPATTQPTVNSESSNKPKN 1221 Score = 30.8 bits (69), Expect = 0.017 Identities = 22/128 (17%), Positives = 41/128 (32%), Gaps = 12/128 (9%) Query: 17 DKEQKQEQTEEQQIVEEQRPVEPPVETAADIDA--QTPAHSKAETEAFAEEVVD------ 68 + EQ E VE PV + ++ + + T A + V+ Sbjct: 1159 QSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Query: 69 VTEKVQESEKPQPVEPEPATAVETAAPQIAVEREELPLPEEVKDEAISPEEWQAEAETVE 128 + + S + P EPAT + + L + +S +A+ + Sbjct: 1219 PKNRHRRSVRSVPHNVEPAT-TSSNDRSTVALCD---LTSTNTNAVLSDARAKAQFVALN 1274 Query: 129 VIAAVEEE 136 V AV + Sbjct: 1275 VGKAVSQH 1282
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 43.2 bits (101), Expect = 1e-06 Identities = 46/176 (26%), Positives = 73/176 (41%), Gaps = 17/176 (9%) Query: 133 SGHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQELADYTAKLRAAGMKCGYASGW 192 +G L++ P L YNKD L P PPKTW+E+ +L+A G + Sbjct: 126 NGKLIAYPIAVEALSLIYNKD------LLP-NPPKTWEEIPALDKELKAKGKSALMFNLQ 178 Query: 193 QGWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIALLEEMNKKGDFSYVG 250 + + +A G F +N +D D ++ K + L++ + D Y Sbjct: 179 EPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY-- 236 Query: 251 RKDESTEKFYNGDCAMTTASSGSLANIRQYAKFNYGVGMMPYDADIKGAPQNAIIG 306 + F G+ AMT + +NI +K NYGV ++P KG P +G Sbjct: 237 --SIAEAAFNKGETAMTINGPWAWSNIDT-SKVNYGVTVLP---TFKGQPSKPFVG 286
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.041 Identities = 10/29 (34%), Positives = 16/29 (55%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTSGDI 61 +V+ G G GKSTL+ + GL+ + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHF 627
>PF04619#Dr-family adhesin Length = 160 Score = 27.6 bits (61), Expect = 0.032 Identities = 11/60 (18%), Positives = 21/60 (35%), Gaps = 4/60 (6%) Query: 29 VGARYGHTMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGGW 84 +G ++ D + G+ FL+ D+N ++ W + D G W Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 36.0 bits (83), Expect = 1e-04 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFSLLEHTFIEYGQTGKGQSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 25.1 bits (54), Expect = 0.024 Identities = 17/46 (36%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 3 IPWQGLAPDTLDNLIESFV---LREGTDYGEHERSLEQKVADVKRQ 45 +PW+ PD L FV E T E E SLEQ++A ++ Q Sbjct: 5 LPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQ 50
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.5 bits (68), Expect = 0.021 Identities = 21/85 (24%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 522 VQKQENQADDAPKENNANSAQSRKDQKRREAELRTLT---QPLRKEITRLEKEMEKLNAQ 578 + E + A +E N N ++ RE E T + + I+ L+ M L A Sbjct: 151 TRTAEEIGEQAVREGNINGPEAYMRFLDREMEGLTAAYNVKLFTEAISSLQIRMNTLTAA 210 Query: 579 LA----QAEEKLGDSSLYDPSRKAE 599 A A K + + + RKAE Sbjct: 211 KASIEAAAANKAREQAAAEAKRKAE 235
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 27.7 bits (61), Expect = 0.025 Identities = 35/138 (25%), Positives = 52/138 (37%), Gaps = 22/138 (15%) Query: 11 YAHPESQDSVANRVLLKPAIQHNNVTVHDLYARYPDFFID--TPYEQ-----ALLREHDV 63 Y P + D N+V P + +HD+ + D F +P + L+ V Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 64 IVFQH--PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLVGKYWRSVITTGEPESA---- 117 Q P+ + P DR L F GPG N G Y +IT PE Sbjct: 69 ---QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLNS--GPYEEKIITELAPEDDDLVL 121 Query: 118 --YRYDALNRYPMSDVLR 133 +RY A R + +++R Sbjct: 122 TKWRYSAFKRTNLLEMMR 139
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 128 bits (323), Expect = 2e-38 Identities = 80/226 (35%), Positives = 121/226 (53%), Gaps = 9/226 (3%) Query: 28 AAKPAATADSKAAFKNDDQKAAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A A + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQTFEARVKSAAQAKMEKDAADNEAKGKTFRDAFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG F A + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLLYKVEKEGTGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL YK+ GTG P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPALAYGKTGVPG-IPANSTLVFDVELLDIKPA 251 + + G ++ +P LAYG V G I N TL+F + L+ +K A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.7 bits (64), Expect = 0.022 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 218 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 219 SK 220 + Sbjct: 114 AT 115
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 616 bits (1591), Expect = 0.0 Identities = 178/698 (25%), Positives = 305/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVGQIKTRLGANPVPLQLAIGAEEGFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMQDLANEWHQNLIESAAEASEELMEKYLGGEELTEEEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KQALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 +Q R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKTARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPENPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P+ ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYREAIRAKVTDIEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKKA---EYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKSGPLAGYPVVDLGVRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D + +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDDAPNNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 186 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 187 AKIIELAGFLDSYIPEPE 204 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 36.8 bits (85), Expect = 1e-05 Identities = 18/103 (17%), Positives = 43/103 (41%), Gaps = 10/103 (9%) Query: 44 EYHESIDEMKHADKYIERILFLEGIPN--LQDLGKL------GIGEDVEEMLRSDLRLEL 95 E ++ E D ER+L + G P +++ + G EM+++ + Sbjct: 52 ELYDHAAE--TVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYK 109 Query: 96 EGAKDLREAIAYADSVHDYVSRDMMIEILADEEGHIDWLETEL 138 + + + + I A+ D + D+ + ++ + E + L + L Sbjct: 110 QISSESKFVIGLAEENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 141 bits (358), Expect = 2e-44 Identities = 59/143 (41%), Positives = 86/143 (60%), Gaps = 2/143 (1%) Query: 4 ALPFLIFYASFSLLLGIYDARTGLLPDRFTCPLLWGGLLYHQICLPERLPDALWGAIAGY 63 L L+ + L D LLPD+ T PLLWGGLL++ + L DA+ GA+AGY Sbjct: 134 TLAALLLT-WVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGDAVIGAMAGY 192 Query: 64 GGFALIYWGYRLRYQKEGLGYGDVKYLAALGAWHCWETLPLLVFLAAMLACGGFGVALLV 123 +YW ++L KEG+GYGD K LAALGAW W+ LP+++ L++++ G+ L++ Sbjct: 193 LVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLV-GAFMGIGLIL 251 Query: 124 RGKSALINPLPFGPWLAVAGFIT 146 P+PFGP+LA+AG+I Sbjct: 252 LRNHHQSKPIPFGPYLAIAGWIA 274
>adhesinb#Adhesin B signature. Length = 310 Score = 29.0 bits (65), Expect = 0.001 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 1 MKR---LIPVALLTTLLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGG 57 MK+ L+ + L LA C+ + +V TN+ + T++ IAG Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN-------IAGD 53 Query: 58 AAAVAGLT 65 + + Sbjct: 54 KINLHSIV 61
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1386 bits (3589), Expect = 0.0 Identities = 914/1032 (88%), Positives = 972/1032 (94%) Query: 1 MANFFIRRPIFAWVLAIILMMAGALAIMQLPVAQYPTIAPPAVSISATYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILMMAGALAI+QLPVAQYPTIAPPAVS+SA YPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSFLMVAGFVSDNPNTTQDDISDYVASNIKDSISRLNGVGDVQLFGA 180 EVQQQGISVEKSSSS+LMVAGFVSDNP TTQDDISDYVASN+KD++SRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDANLLNKYQLTPVDVINQLTVQNDQIAAGQLGGTPALPGQQLNASIIAQTRL 240 QYAMRIWLDA+LLNKY+LTPVDVINQL VQNDQIAAGQLGGTPALPGQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KDPQEFGKVTLRVNTDGSVVHLKDVARIELGGENYNVVARINGKPASGLGIKLATGANAL 300 K+P+EFGKVTLRVN+DGSVV LKDVAR+ELGGENYNV+ARINGKPA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTATAIKAKLAELQPFFPQGMKVVYPYDTTPFVKISIHEVVKTLFEAIILVFLVMYLFLQ 360 DTA AIKAKLAELQPFFPQGMKV+YPYDTTPFV++SIHEVVKTLFEAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NIRATLIPTIAVPVVLLGTFAVLAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N+RATLIPTIAVPVVLLGTFA+LAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDNLSPREATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MED L P+EATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPVSAEHHEKKSGFFGWFNTRFDHSVNHYTNSVSGIVRNTGRY 540 SVLVALILTPALCATLLKPVSAEHHE K GFFGWFNT FDHSVNHYTNSV I+ +TGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LIIYLLIVVGMAVLFLRLPTSFLPEEDQGVFLTMIQLPSGATQERTQKVLDQVTHYYLNN 600 L+IY LIV GM VLFLRLP+SFLPEEDQGVFLTMIQLP+GATQERTQKVLDQVT YYL N Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQGQNSGMAFVSLKPWEERNGEENSVEAVIARATRAFSQIRDG 660 EKANVESVFTVNGFSFSGQ QN+GMAFVSLKPWEERNG+ENS EAVI RA +IRDG Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 LVFPFNMPAIVELGTATGFDFELIDQGGLGHDALTKARNQLLGMVAKHPDLLVRVRPNGL 720 V PFNMPAIVELGTATGFDFELIDQ GLGHDALT+ARNQLLGM A+HP LV VRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTPQFKLDVDQEKAQALGVSLSDINETISAALGGYYVNDFIDRGRVKKVYVQADAQLRM 780 EDT QFKL+VDQEKAQALGVSLSDIN+TIS ALGG YVNDFIDRGRVKK+YVQADA+ RM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPGDINNLYVRSANGEMVPFSTFSSARWIYGSPRLERYNGMPSMELLGEAAPGRSTGEAM 840 LP D++ LYVRSANGEMVPFS F+++ W+YGSPRLERYNG+PSME+ GEAAPG S+G+AM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 SLMENLASQLPNGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFSV 900 +LMENLAS+LP GIGYDWTGMSYQERLSGNQAPAL AIS +VVFLCLAALYESWSIP SV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGVVGALLAASLRGLNNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMEKEGRGLI 960 MLVVPLG+VG LLAA+L NDVYF VGLLTTIGLSAKNAILIVEFAKDLMEKEG+G++ Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLEASRMRLRPILMTSLAFILGVMPLVISRGAGSGAQNAVGTGVMGGMLTATLLAIFF 1020 EATL A RMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGM++ATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVVKRRF 1032 VPVFFVV++R F Sbjct: 1021 VPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 2e-06 Identities = 24/137 (17%), Positives = 48/137 (35%), Gaps = 15/137 (10%) Query: 98 ATYQADYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 + K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 VAAKAAVESARINLAYTKVTSPISGRIGKSNV-TEGALVTNGQSTELATVQQLDPIYVDV 215 + + + +P+S ++ + V TEG +VT + T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVE 230 + D F+ + Q+ Sbjct: 371 LVQNKDIGFINVGQNAI 387 Score = 37.1 bits (86), Expect = 1e-04 Identities = 22/127 (17%), Positives = 41/127 (32%), Gaps = 13/127 (10%) Query: 46 TAPLAVTTELPGR-TSAFRIAEVRPQVSGIVLKRNFTEGSDVEAGQSLYQIDPATYQADY 104 + + G+ T + R E++P + IV + EG V G L ++ +AD Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEAD- 135 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVVAAKAAVE 164 K++++ A L RY L E ++ + Sbjct: 136 ------TLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 128 bits (324), Expect = 2e-39 Identities = 82/216 (37%), Positives = 130/216 (60%), Gaps = 3/216 (1%) Query: 1 MAKKTKADALKTRQHLIETAIAQFALRGVANTTLNDIADAADVTRGAIYWHFENKTQLFN 60 MA+KTK +A +TRQH+++ A+ F+ +GV++T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EVW-LQQPPLRELIQDRLTGCWNDNPLQDLREKFIAALQYIAAVPRQQALMQILYHKCEF 119 E+W L + + EL + +PL LRE I L+ R++ LM+I++HKCEF Sbjct: 61 EIWELSESNIGELELEYQAKF-PGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 HNGM-ISEQAIREKMGFHHQSMLEVLQRCMDKKLISGSLDLDVILIILHGSFSGIVKNWL 178 M + +QA R + + + L+ C++ K++ L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNPTSYDLYKQAPALVDNVLKMLSPDGSVRQLMPNE 214 P S+DL K+A V +L+M ++R NE Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.009 Identities = 14/55 (25%), Positives = 22/55 (40%), Gaps = 16/55 (29%) Query: 4 VLITGATGLVGGHLLRMLINTPQVSAIAAPTRRPLTDIVGV--YNP-HDPQLTDA 55 L+TGA G +G H+ + L+ +VG+ N +D L A Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGH-------------QVVGIDNLNDYYDVSLKQA 44
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.0 bits (62), Expect = 0.028 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 22/111 (19%) Query: 42 NKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIA-------NDRL 94 K+L GN + A T + IA + V AI+ D+ Sbjct: 277 TKVL--GNVGKGISQYIIAQRAAQGLSTSAAAAGLIA----SAVTLAISPLSFLSIADKF 330 Query: 95 HD----EVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVA 141 E Y+++ + LG+ GD LLA + A++A++T T++A Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETG-----AIDASLTTISTVLA 376
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.9 bits (77), Expect = 0.003 Identities = 24/120 (20%), Positives = 38/120 (31%), Gaps = 8/120 (6%) Query: 289 QAVEMQPAAAPDAPVEPGVEETQPQMTNGVASPSQASVSDLTDDAPSQSATPVSAPQTPP 348 Q+ +QP A P +P V +PQ + A + S PV+ T Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTN----TTADTEQPAKETSSNVEQPVTESTTVN 1190 Query: 349 ATASAPADPSAELKIYDTSSQPLD-QVLAQVQQDGASIVVGPLLKNNVEALMKSNTPLNV 407 S +P ++QP + ++ V + N A SN V Sbjct: 1191 TGNSVVENPENTT---PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTV 1247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 38.1 bits (88), Expect = 3e-05 Identities = 26/92 (28%), Positives = 39/92 (42%), Gaps = 2/92 (2%) Query: 156 AQGCEGKNVIIVGAGT-IGLLALQCARELGARSVTAIDINPQKLELAKALGATHTCNSRE 214 A+G EGK I GA IG + GA + A+D NP+KLE + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MTADDIQTALSDIQFDQLVLETAGTPQTVSLA 246 AD +A D ++ E V++A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>LUXSPROTEIN#Bacterial autoinducer-2 (AI-2) production protein LuxS signature. Length = 171 Score = 287 bits (736), Expect = e-103 Identities = 130/170 (76%), Positives = 145/170 (85%) Query: 2 PLLDSFAVDHTRMQAPAVRVAKTMNTPHGDAITVFDLRFCIPNKEVMPEKGIHTLEHLFA 61 PLLDSF VDHTRM APAVRVAKTM TP GD ITVFDLRF PNK+++ EKGIHTLEHL+A Sbjct: 1 PLLDSFTVDHTRMNAPAVRVAKTMQTPKGDTITVFDLRFTAPNKDILSEKGIHTLEHLYA 60 Query: 62 GFMRDHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVADAWKAAMADVLKVQDQNQIP 121 GFMR+HLNG+ VEIIDISPMGCRTGFYMSLIGTP EQ+VADAW AAM DVLKV++QN+IP Sbjct: 61 GFMRNHLNGDSVEIIDISPMGCRTGFYMSLIGTPSEQQVADAWIAAMEDVLKVENQNKIP 120 Query: 122 ELNVYQCGTYQMHSLSEAQDIARHILERDVRVNSNKELALPKEKLQELHI 171 ELN YQCGT MHSL EA+ IA++ILE V VN N ELALP+ L+EL I Sbjct: 121 ELNEYQCGTAAMHSLDEAKQIAKNILEVGVAVNKNDELALPESMLRELRI 170
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 129 bits (326), Expect = 7e-35 Identities = 94/405 (23%), Positives = 164/405 (40%), Gaps = 23/405 (5%) Query: 17 IALSLATFMQVLDSTIANVAIPTIAGNLGSSLSQGTWVITSFGVANAISIPLTGWLAKRF 76 I L + +F VL+ + NV++P IA + + WV T+F + +I + G L+ + Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVKLFMWSTVAFAAASWACGVS-SSLNMLIFFRVVQGVVAGPLIPLSQSLLLNNYPPAK 135 G +L ++ + S V S ++LI R +QG A L ++ P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RSIALALWSMTVIVAPICGPILGGYISDNYHWGWIFFINVPIGIAVVLMTLHTLRGRETH 195 R A L V + GP +GG I+ HW ++ I + I I V + L+ Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKKEVRI 195 Query: 196 TERRRIDAVGLALLVIGIGSLQIMLDRGKELDWFSSQEIIILTVVAVIAISFLIVWELTD 255 D G+ L+ +GI + ML F++ I +V+V++ + Sbjct: 196 KG--HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 256 DHPIVDLSLFKSRNFTIGCLCISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGI 315 P VD L K+ F IG LC + + G + ++P ++++V+ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 316 IPVILS-PIIGRFAHKLDMRRLVTFSFIMYAVCFYWRAWTFEPGMDFGASAWPQFIQGF- 373 + VI+ I G + ++ +V F ++ S + I F Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFMTIIIVFV 358 Query: 374 --AVACFFMPLTTITLSGLPPERLAAASSLSNFTRTLAGSIGTSI 416 ++ ++TI S L + A SL NFT L+ G +I Sbjct: 359 LGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 74.1 bits (182), Expect = 2e-16 Identities = 61/418 (14%), Positives = 125/418 (29%), Gaps = 97/418 (23%) Query: 19 KRKTALLLLTLLFVIIAVAYGIYWFLVLRHIEETDDA----YVAGNQVQIMAQVSGSVTK 74 + L F++ + VL +E A +G +I + V + Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILS-VLGQVEIVATANGKLTHSGRSKEIKPIENSIVKE 109 Query: 75 VWADNTDFVKEGDVLVTLDQT--------------------------------------- 95 + + V++GDVL+ L Sbjct: 110 IIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELK 169 Query: 96 -------------DAKQAFERAKTALASSVRQTHQLMINSKQ-------LQANIDVQKTA 135 + + K ++ Q +Q +N + + A I+ + Sbjct: 170 LPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENL 229 Query: 136 LAQAQSDLNRRVPLGNANLIGREELQHARDAVASAQAQLDVAIQQYNSNQAMILNSNLED 195 +S L+ L + I + + + A +L V Q ++ IL++ E Sbjct: 230 SRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEY 289 Query: 196 QPAVQQAATEVRN------------------AWLALERTRIVSPMTGYVSRRAVQ-PGAQ 236 Q Q E+ + + + I +P++ V + V G Sbjct: 290 QLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 237 ISPTTPLMAVVPATD-LWVDANFKETQLANMRIGQPVTVITDIYGDDVKY---TGKVVGL 292 ++ LM +VP D L V A + + + +GQ + + + +Y GKV + Sbjct: 350 VTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNI 408 Query: 293 DMGTGSAFSLLPAQNATGNWIKVVQRLPVRVELDARQLEQHPLRIGLSTLVTVDTANR 350 + ++ G V+ + + PL G++ + T R Sbjct: 409 -----NLDAIE--DQRLGLVFNVIISIEENCLSTGNK--NIPLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.4 bits (110), Expect = 1e-07 Identities = 31/165 (18%), Positives = 66/165 (40%), Gaps = 2/165 (1%) Query: 34 LDTIAHHFSLSASSAGFIVTAAQLGYAAGLLFLVPLGDMFE-RRTLIVSMTLLAAGGMLI 92 L IA+ F+ +S ++ TA L ++ G L D +R L+ + + G ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 93 TASSQSLSMMILGTALTGLFSVVAQILVPLA-ATLATPATRGKVVGTIMSGLLLGILLAR 151 S++I+ + G + LV + A RGK G I S + +G + Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 152 TVAGLLANLGGWRTVFWVASALMALMAVALWRGLPKLKSDTHLNY 196 + G++A+ W + + + + + +++ H + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.4 bits (66), Expect = 0.014 Identities = 8/55 (14%), Positives = 17/55 (30%) Query: 277 FAIMKLPLADINAQNAMMHAGKSSEADVQGHVDGWINAHQQQFDGWVKEALAAQK 331 F + ++P + S +D + HV + + Q + Q Sbjct: 133 FVLNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVTSDNQSARYLTLPEVNKQT 187
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 27.6 bits (61), Expect = 0.026 Identities = 16/78 (20%), Positives = 30/78 (38%), Gaps = 8/78 (10%) Query: 49 GSRVLESSPAQMTAAVDVSKAGISKTFTTRNQLTRNQSILMHLVDGPFKKLIGGWK---- 104 G+ VLE P+ + +D G + + LT I +++G +++ + Sbjct: 113 GNAVLEVDPSITFSIIDRLFGGTGQAAKVQRDLT---DIENSVMEGVIVRILANVRESWT 169 Query: 105 -FTPLSPEACRIEFQLDF 121 L P +IE F Sbjct: 170 QVIDLRPRLGQIETNPQF 187
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.3 bits (71), Expect = 0.009 Identities = 31/198 (15%), Positives = 64/198 (32%), Gaps = 36/198 (18%) Query: 177 QQQSQERAARAELLQYQLKELNDFNPQAGEFEQIDEEYKRLANSGQLLTTSQNALALLAD 236 + QS AR E +YQ+ + + E + DE Y + + ++L + + Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS- 196 Query: 237 GEDVNLQSQLYSAKQLVSELVGMDSKLSGILDMLEEATIQLTEASDELRHYCERLDLDPN 296 Q+Q Y Q L ++ +L A I E + Sbjct: 197 ----TWQNQKY---QKELNLDKKRAERLTVL-----ARINRYENLSRV------------ 232 Query: 297 RLFELEQRIAKQISLARKHHVSPEALPQLYQSLLEEQQQLDDQADSLETLTLAVNKHHQQ 356 + R+ SL K ++ ++LE++ + + + L + + + Sbjct: 233 ----EKSRLDDFSSLLHKQAIA-------KHAVLEQENKYVEAVNELRVYKSQLEQIESE 281 Query: 357 ALETAQALHQQRQFYAQE 374 L + Q + E Sbjct: 282 ILSAKEEYQLVTQLFKNE 299
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.0 bits (78), Expect = 0.001 Identities = 72/429 (16%), Positives = 140/429 (32%), Gaps = 45/429 (10%) Query: 28 IQALLSVFLGYLAYYIVRNNFTLSTPYLKEQLDLSATQI---GLLSSCMLIAYGISKGVM 84 I L +V L + ++ P L L S G+L + + V+ Sbjct: 8 IVILSTVALDAVGIGLI----MPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 85 SSLADKASPKVFMACGLVLCAIVNVGLGFSSAFWIFAALVVFNGLFQGMGVGPSFITIAN 144 +L+D+ + + L A+ + + W+ + G+ G IA+ Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 145 WFPRRERGRVGAFWNISHNVGGGIVA-PIVGAAFAILGSEHWQSASYIVPACVAIIFALI 203 ER R F +S G G+VA P++G A + A + + L Sbjct: 123 ITDGDERAR--HFGFMSACFGFGMVAGPVLGGLMGGFSPH----APFFAAAALNGLNFLT 176 Query: 204 VLVLGKGSPREEGLPSLEQMMPEEKVVLKTKNMAKAPENMSAWQIFCTYVLRNKNAWYIS 263 L +PE + + P A ++ + Sbjct: 177 GCFL----------------LPE------SHKGERRPLRREALNPLASFRWARGMTVVAA 214 Query: 264 LVDVFVYMVRFGMISWLPIYLLTVKHFSKEQMSVAFLFFEWA---AIPSTLLAGWLSDKL 320 L+ VF M G + + F + ++ + ++ ++ G ++ +L Sbjct: 215 LMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARL 274 Query: 321 FKGRRMPLAMICMALIFVCLIGYWKSESLLMVTIFAAIVGCLIYVPQFLASVQTMEIVPS 380 + R + L MI ++ L + + + A G + Q + S Q E Sbjct: 275 GERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQG 334 Query: 381 FAVGSAVGLRGFMSYIFGASLGTSLFGVMVDKLGWYGGFYLLMGGIVCCILFCYLSHRGA 440 GS L ++ I G L T+++ + + G+ + G + + L RG Sbjct: 335 QLQGSLAALTS-LTSIVGPLLFTAIYAA---SITTWNGWAWIAGAALYLLCLPAL-RRGL 389 Query: 441 LELERQRQN 449 QR + Sbjct: 390 WSGAGQRAD 398
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 28.7 bits (64), Expect = 0.050 Identities = 5/35 (14%), Positives = 15/35 (42%), Gaps = 4/35 (11%) Query: 330 QQLVQRMFDTAISFRLAQLKDAWRALHSAETRLKR 364 +++ + LA ++++W + RL + Sbjct: 150 NSVMEGVIVRI----LANVRESWTQVIDLRPRLGQ 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 248 bits (636), Expect = 4e-80 Identities = 120/474 (25%), Positives = 192/474 (40%), Gaps = 73/474 (15%) Query: 7 SILLIDDDVDVLDAYTQMLEQAGYRVRGFTHPFEAKEWVKADWEGIVLSDVCMPGCSGID 66 +IL+ DDD + Q L +AGY VR ++ W+ A +V++DV MP + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 LMTLFHQDDDQLPILLITGHGDVPMAVDAVKKGAWDFLQKPVDPGKLLILIEDALRQRRS 126 L+ + LP+L+++ A+ A +KGA+D+L KP D +L+ +I AL + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 127 VIARRQYCQQTLQVELIGRSEWMNQFRQRLQQLAETDIAVWFYGEHGTGRMTGARYLHQL 186 ++ + Q L+GRS M + + L +L +TD+ + GE GTG+ AR LH Sbjct: 125 RPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDY 183 Query: 187 GRNAKGPFVRYELT--PENAGQLETF-----------------IDQAQGGTLVLSHPEYL 227 G+ GPFV + P + + E F +QA+GGTL L + Sbjct: 184 GKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDM 243 Query: 228 TREQQHHLAR-LQSLEHRP----------FRLVGVGSASLVEQAAANQIAAELYYCFAMT 276 + Q L R LQ E+ R+V + L + +LYY + Sbjct: 244 PMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVV 303 Query: 277 QIACQSLSQRPDDIEPLFRHYLRKACLRLNHPVPEIAGELLKGIMRRAWPSNVRELANAA 336 + L R +DI L RH++++A + V E L+ + WP NVREL N Sbjct: 304 PLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 337 ELFAV-----------------------------------GVLPLAETVNPQLL------ 355 + E Q Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDA 422 Query: 356 LQEPTPLDRRVEEYERQIITEALNIHQGRINEVAEYLQIPRKKLYLRMKKYGLS 409 L DR + E E +I AL +G + A+ L + R L ++++ G+S Sbjct: 423 LPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 475 bits (1224), Expect = e-173 Identities = 148/320 (46%), Positives = 213/320 (66%), Gaps = 11/320 (3%) Query: 1 MKKHAIAVMMIAVFSESVYAESTLFIPDVSPESVTTSLSVGVLNGKSRELVYD-TDTGRK 59 M+ + +++ + S +A + +P+++ +S+G L+GK++E VY + GRK Sbjct: 1 MRAKLLGIVLTTPIAISSFASTET--LSFTPDNINADISLGTLSGKTKERVYLAEEGGRK 58 Query: 60 LSQLDWKIKNVATLQGDLSWEPYSFMTLDARGWTSLASGSGHMVDHDWMSSEQPG-WTDR 118 +SQLDWK N A ++G ++W+ +++ A GWT+L S G+MVD DWM S PG WTD Sbjct: 59 VSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDE 118 Query: 119 SIHPDTSVNYANEYDLNVKGWLLQGDNYKAGVTAGYQETRFSWTARGGSYIYDNGR---- 174 S HPDT +NYANE+DLN+KGWLL NY+ G+ AGYQE+R+S+TARGGSYIY + Sbjct: 119 SRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRD 178 Query: 175 YIGNFPHGVRGIGYSQRFEMPYIGLAGDYRINDFECNVLFKYSDWVNAHDNDEHY--MRK 232 IG+FP+G R IGY QRF+MPYIGL G YR DFE FKYS WV + DNDEHY ++ Sbjct: 179 DIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKR 238 Query: 233 LTFREKTENSRYYGASIDAGYYITSNAKIFAEFAYSKYEEGKGGTQIIDKTSGDTAYFGG 292 +T+R K ++ YY +++AGYY+T NAK++ E A+++ KG T + D + +T+ + Sbjct: 239 ITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNN-NTSDYSK 297 Query: 293 DAAGIANNNYTVTAGLQYRF 312 + AGI N N+ TAGL+Y F Sbjct: 298 NGAGIENYNFITTAGLKYTF 317
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.030 Identities = 22/113 (19%), Positives = 46/113 (40%), Gaps = 12/113 (10%) Query: 199 WIIATMVWMFPAAGGAKIVVIILMTWLIALGDTTHIVVGSVEILYLV-FNGTLPWSDFLW 257 I W+ G I+ ++ +I + V + I L+ F T P + F Sbjct: 61 SFIKRQGWLKLNMG-QIILRVLPACVVIGM----VWFVANTSIWRLLAFINTKPVA-FTL 114 Query: 258 PFALPTLAGNICGGTFIFALMSHAQIRNDMSNKRKEEARLRGERLERERKKAE 310 P AL ++ N+ TF+++L+ K ++A + ++ ++A+ Sbjct: 115 PLAL-SIIFNVVVVTFMWSLLYFGWHFF----KNYKQAEIDQWKMASMAQEAQ 162
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 398 bits (1025), Expect = e-144 Identities = 238/251 (94%), Positives = 248/251 (98%) Query: 1 MKLRLSALALGTTLLVGCASSGTEQQGRSDPFEGFNRTMYNFNFNVLDPYVVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGT+QQGRSDP EGFNRTMYNFNFNVLDPY+VRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAIMVNYFLQGDPYQGMVHFTRFFLNTLLGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPA+MVNYFLQGDPYQGMVHFTRFFLNT+LGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRVEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLREDGGDMADTLYPVLSWLTWPM 180 ANPKLQR EPHRFGSTLGHYGVGYGPYVQLPFYGSFTLR+DGGDMAD LYPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SIGKWTIEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGKLKPQENPNAQA 240 S+GKWT+EGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGG+LKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDELKEIDSE 251 IQD+LK+IDSE Sbjct: 241 IQDDLKDIDSE 251
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 28.7 bits (64), Expect = 0.029 Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 6/63 (9%) Query: 204 VRNIVGS-LLEVGAHNQPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRFDLPKPP 262 +NI GS ++ + PES + E AA LAA +K++ V VDY + ++ KP Sbjct: 496 TKNIPGSHVIVKNIMDIPESTLLE--AAN---LAAYYSKSQNSSNVPVDYTEVKNVKKPN 550 Query: 263 MGP 265 Sbjct: 551 GAK 553
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 29.7 bits (66), Expect = 0.008 Identities = 22/89 (24%), Positives = 34/89 (38%), Gaps = 19/89 (21%) Query: 53 PDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPSRMASNNVELDPIPAETPKPKPQPK 112 PD+ P + +A QP P + P+ +NN P P E P +P P+ Sbjct: 313 PDLTPGSAEAPNAQP--------------LPEVSPAENPANN----PAPNENPGTRPNPE 354 Query: 113 PQQPVVVASTPTPAPKPAAD-DKPAPTGK 140 P + + P +P D PA + Sbjct: 355 PDPDLNPDANPDTDGQPGTRPDSPAVPDR 383
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 33.6 bits (76), Expect = 0.002 Identities = 13/37 (35%), Positives = 24/37 (64%), Gaps = 2/37 (5%) Query: 469 KDVDQQYLDFLDSLRND-DAKAVLFQNEM-ENLEMHN 503 K +D ++L+ + SL +D D+ +LF + E LE++N Sbjct: 186 KSLDPEFLNLIKSLSDDSDSSDLLFSQKFKEKLELNN 222
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 348 bits (894), Expect = e-118 Identities = 121/371 (32%), Positives = 185/371 (49%), Gaps = 24/371 (6%) Query: 122 NMSGVRRLQEQVVELNQLLYADHHE---KHHAIITENPEMLSNIAKAKRLAASNIPVTIV 178 +++ + + + + + + + ++ + M RL +++ + I Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166 Query: 179 GETGTGKELFSRLIHQCSKRANKPFIALNCGALPPTLIESTLFGTVRGAYTGAENS-QGY 237 GE+GTGKEL +R +H KR N PF+A+N A+P LIES LFG +GA+TGA+ G Sbjct: 167 GESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGR 226 Query: 238 LELANGGTLFLDELNAMPIEMQSKLLRFLQDKTFWRLGGQQQLHSDVRIVAAMNEAPVKL 297 E A GGTLFLDE+ MP++ Q++LLR LQ + +GG+ + SDVRIVAA N+ + Sbjct: 227 FEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQS 286 Query: 298 IQQERLRADLFYRLSVGMLTLPPLRARPEDIPLLANYFIDKYRNDVPQDIHGLSETARAD 357 I Q R DL+YRL+V L LPPLR R EDIP L +F+ + + D+ + A Sbjct: 287 INQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALEL 345 Query: 358 LLNHAWPGNVRMLENAIVRSMIMQEKDGLLKHIIF-------------------EQDELN 398 + H WPGNVR LEN + R + +D + + II ++ Sbjct: 346 MKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSIS 405 Query: 399 LGVPETAPENPLPSSPDPQYEGSLEVRVANYERHLIETALDTHQGNIAAAARSLNVSRTT 458 V E + G + +A E LI AL +GN AA L ++R T Sbjct: 406 QAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNT 465 Query: 459 LQYKVQKYAIR 469 L+ K+++ + Sbjct: 466 LRKKIRELGVS 476
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 31.7 bits (72), Expect = 0.006 Identities = 23/133 (17%), Positives = 47/133 (35%), Gaps = 20/133 (15%) Query: 87 VLKAIRDAGICAEANSQYEVRKCLEIGFRGDQIVFNGVVKKPADLEYAIANDLYLINVDS 146 + AI A N + E E G++G ++ G DLE + L Sbjct: 46 IWSAIGATDGFALLNLE-EAITLRERGWKGPILMLEGFFH-AQDLEIYDQHRLTT----C 99 Query: 147 LYELEHIDAIS-RKLKKVANVCVRVEPNVPSATHAELVTAFHAKSGLDLEQAEETCRRIL 205 ++ + A+ +LK ++ ++V + + + G ++ +++ Sbjct: 100 VHSNWQLKALQNARLKAPLDIYLKVN------------SGMN-RLGFQPDRVLTVWQQLR 146 Query: 206 AMPYVHLRGLHMH 218 AM V L H Sbjct: 147 AMANVGEMTLMSH 159
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 6e-06 Identities = 36/172 (20%), Positives = 71/172 (41%), Gaps = 10/172 (5%) Query: 123 KVALAQAQGQLAKDNATLANARRDLARYQQ---LAKTNLVSRQELDAQQAL--VNETQGT 177 K A+ + + + + L + L + + AK +L + L + +T Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 178 IKADEANVASAQLQLDWSRITAPVSGRV-GLKQVDVGNQISSSDTAGIVVITQTHPIDLI 236 I +A + + S I APVS +V LK G +++++T +V++ + +++ Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVT 369 Query: 237 FTLPESDIATVVQAQKAGKALVVEAWDRTNSHKL-SEGVLLSLDNQIDPTTG 287 + DI + Q A + VEA+ T L + ++LD D G Sbjct: 370 ALVQNKDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419 Score = 40.6 bits (95), Expect = 8e-06 Identities = 20/122 (16%), Positives = 46/122 (37%), Gaps = 13/122 (10%) Query: 79 GTVTAA-NTVTVRSRVDGQLIALHFQEGQQVNAGDLLAQIDPSQFKVALAQAQGQLAKDN 137 G +T + + ++ + + + +EG+ V GD+L ++ + + Q Sbjct: 88 GKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQ------- 140 Query: 138 ATLANARRDLARYQQLAKTNLVSRQELDAQQALVNETQGTIKADEANVASAQLQLDWSRI 197 ++L AR + RYQ L+++ EL+ L + + L + Sbjct: 141 SSLLQARLEQTRYQILSRS-----IELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Query: 198 TA 199 + Sbjct: 196 ST 197
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 5e-09 Identities = 32/129 (24%), Positives = 56/129 (43%), Gaps = 20/129 (15%) Query: 132 AMMVHIRHTAHSQ-LPEAITQAVIGRPINFQGLGGDDANRQAQGILERAAKRAGFQEVVF 190 M+ H HS + ++ P+ R+A + +A+ AG +EV Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGA-----TQVERRA---IRESAQGAGAREVFL 140 Query: 191 QYEPVAAGLDYEATLREEKRVLVVDIGGGTTDCSMLLMGPQWRQRADRENSLLGHSGCRV 250 EP+AA + + E +VVDIGGGTT+ +++ + ++ S R+ Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 251 GGNDLDIAL 259 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 35.1 bits (81), Expect = 5e-04 Identities = 33/137 (24%), Positives = 55/137 (40%), Gaps = 23/137 (16%) Query: 332 RLSYRLV---RCAEESKIALSG--QADITARLPFISDDLA------VAISQQGLEAALDQ 380 R +Y + AE K + D + +LA ++ + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 381 PLARILEQVQLALDSAQEKPDV--------IYLTGGSARSPLIKKALSEQLPGIPVAGGD 432 PL I+ V +AL+ Q P++ + LTGG A + + L E+ GIPV + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 433 D-FGSVTAGLARWAEVV 448 D V G + E++ Sbjct: 320 DPLTCVARGGGKALEMI 336
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.005 Identities = 17/84 (20%), Positives = 36/84 (42%), Gaps = 1/84 (1%) Query: 138 STTAEGAQRRLAEYIQQVDEEVAKELEVDLKDNITLQTKTLQESLETQEVVAQEQKDLRI 197 +T R +A+ + + + EV + T +T+T E+ ET V +E+ + Sbjct: 1058 ATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT-TETKETATVEKEEKAKVET 1116 Query: 198 KQIEEALRYADEAKITQPQIQQTQ 221 ++ +E + + Q Q + Q Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQ 1140
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 27.9 bits (62), Expect = 0.024 Identities = 19/102 (18%), Positives = 35/102 (34%), Gaps = 13/102 (12%) Query: 105 FGDASHQWLFLYQLEQLLAERKTADPASSYTAKLYASGTKRIAQKVGEE---GVETALAA 161 + S Q+ L L L R P ++ + L +A++ GE G A Sbjct: 129 SEEPSEQFKMLCGLRDALKGR----PELAHLSHLVEQALVSMAEEQGETIVLGARITPEA 184 Query: 162 TVNDRFELTNEAS--DLMYHLLVLLQDQDLNLTAVIDNLRKR 201 + + D ++ Q + A+ +L+KR Sbjct: 185 YRESQSGVNPLQPLRDTYRDAVMGYQ----GIYAIWSDLQKR 222
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 367 bits (944), Expect = e-133 Identities = 192/235 (81%), Positives = 209/235 (88%), Gaps = 7/235 (2%) Query: 1 MSNELPWQVWTPDDLAPPPETFVPVEADNVTLTDDTPEPELTAEQQLEQELAQLKIQAHE 60 MS+ LPW+ WTPDDLAPP FVP+ T+ ++ AE LEQ+LAQL++QAHE Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEE-------AEPSLEQQLAQLQMQAHE 53 Query: 61 QGYNAGLAEGRQKGHAQGYQEGLAQGLEQGQAQAQTQQAPIHARMQQLVSEFQNTLDALD 120 QGY AG+AEGRQ+GH QGYQEGLAQGLEQG A+A++QQAPIHARMQQLVSEFQ TLDALD Sbjct: 54 QGYQAGIAEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALD 113 Query: 121 SVIASRLMQMALEAARQVIGQTPAVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRV 180 SVIASRLMQMALEAARQVIGQTP VDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRV Sbjct: 114 SVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRV 173 Query: 181 EEMLGATLSLHGWRLRGDPTLHHGGCKVSADEGDLDASVATRWQELCRLAAPGVL 235 ++MLGATLSLHGWRLRGDPTLH GGCKVSADEGDLDASVATRWQELCRLAAPGV+ Sbjct: 174 DDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 339 bits (870), Expect = e-118 Identities = 114/329 (34%), Positives = 196/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLSGTDKSVILLMTIGEDRAAEVFKHLSTREVQALSTAMANVRQISNKQLTDVLSEFE 60 +S L+G K+ ILL++IG + +++VFK+LS E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANEYLRSVLVKALGEERASSLLEDILETRDTTSGIETLNFMEPQSAAD 120 + + +Y R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLKRSQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEPPLREKFLRNMSQRAADILRDDLANRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 786 bits (2031), Expect = 0.0 Identities = 558/559 (99%), Positives = 559/559 (100%) Query: 2 SATASTATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQ 61 SATASTATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQ Sbjct: 1 SATASTATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQ 60 Query: 62 DGGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKF 121 DGGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKF Sbjct: 61 DGGAIVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKF 120 Query: 122 GISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLE 181 GISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLE Sbjct: 121 GISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLE 180 Query: 182 PGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDV 241 PGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDV Sbjct: 181 PGRALDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDV 240 Query: 242 ESRIQRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNIS 301 ESRIQRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNIS Sbjct: 241 ESRIQRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNIS 300 Query: 302 EQVGAGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRNTQRN 361 EQVGAGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPR+TQRN Sbjct: 301 EQVGAGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRN 360 Query: 362 ETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMG 421 ETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMG Sbjct: 361 ETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMG 420 Query: 422 FSDKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVR 481 FSDKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVR Sbjct: 421 FSDKRGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVR 480 Query: 482 PQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSD 541 PQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSD Sbjct: 481 PQLTRRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSD 540 Query: 542 NDPRVVALVIRQWMSNDHE 560 NDPRVVALVIRQWMSNDHE Sbjct: 541 NDPRVVALVIRQWMSNDHE 559
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 114 bits (286), Expect = 1e-36 Identities = 90/103 (87%), Positives = 96/103 (93%) Query: 2 AAIQGIEGVISQLQATAMAARGQDTHSQSTVSFAGQLHAALDRISDRQTAARVQAEKFTL 61 +AIQGIEGVISQLQATAM+AR Q++ Q T+SFAGQLHAALDRISD QTAAR QAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGIALNDVMADMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPG+ALNDVM DMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.025 Identities = 10/53 (18%), Positives = 17/53 (32%), Gaps = 2/53 (3%) Query: 164 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFIGMIGWALLT 214 R L R + + + A L + P R R M + ++L Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLG 78
>PF05844#YopD protein Length = 295 Score = 31.9 bits (72), Expect = 0.002 Identities = 12/28 (42%), Positives = 21/28 (75%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQQGMFSLERDIEN 103 ++LL +L+R+ K+R+ G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 42.2 bits (99), Expect = 1e-06 Identities = 25/118 (21%), Positives = 46/118 (38%), Gaps = 11/118 (9%) Query: 162 FKTGSAEVEPYMRDILRAIAPVL---NGIPNRISLAGHTDDFPYANGEKGYSNWELSADR 218 F A ++P + L + L + + + G+TD G Y N LS R Sbjct: 223 FNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRI----GSDAY-NQGLSERR 277 Query: 219 ANASRRELVAGGLDNGKVLRVVGMAATMRLSDRGPDDAINRR--ISLLVLNKQAEQAI 274 A + L++ G+ K+ GM + ++ D+ R I L +++ E + Sbjct: 278 AQSVVDYLISKGIPADKI-SARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 7e-06 Identities = 23/151 (15%), Positives = 49/151 (32%), Gaps = 52/151 (34%) Query: 376 ELDKSLIERIIDPLT--HLVRNSLDHGIEMPEKRLEAGKNVVGNLILSAEHQGGNICIEV 433 +++ ++++ + P+ LV N + HGI G ++L G + +EV Sbjct: 245 QINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTLEV 296 Query: 434 TDDGAGLNRERILAKAMSQGMAVNENMTDDEVGMLIFAPGFSTAEQVTDVSGRGVGMDVV 493 + G+ + G G+ V Sbjct: 297 ENTGSLALKNTK--------------------------------------ESTGTGLQNV 318 Query: 494 KRNIQEMGG---HVEIQSKQGSGTTIRILLP 521 + +Q + G +++ KQG +L+P Sbjct: 319 RERLQMLYGTEAQIKLSEKQG-KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.5 bits (157), Expect = 1e-13 Identities = 30/141 (21%), Positives = 61/141 (43%), Gaps = 6/141 (4%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 SEMIAEKVRTAARARIAAHKP 140 +AE R ++ + Sbjct: 116 GRALAEPKRRPSKLEDDSQDG 136
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.7 bits (220), Expect = 7e-24 Identities = 29/105 (27%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGFGFIISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG +++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADSAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 420 bits (1082), Expect = e-149 Identities = 102/351 (29%), Positives = 179/351 (50%), Gaps = 14/351 (3%) Query: 7 DDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVCIIWFGGESLARQLAGMLSAGLH 66 +KTE PTP ++ AR++GQ+ +S+E+ S +++ ++ + + ++ + Sbjct: 3 GEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLML--IP 60 Query: 67 FDHRMVNDPNLILGQIILLIKAAMMALLPLIAGVVLVALISPVMLGGLIFSGKSLQPKFS 126 + + + + ++ PL+ L+A+ S V+ G + SG++++P Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 127 KLNPLPGIKRMFSAQTGAELLKAVLKSTLVGCVTGFYLWHNWPQMMRLMAESPIVAMGNA 186 K+NP+ G KR+FS ++ E LK++LK L+ + + N +++L P + Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQL----PTCGIECI 176 Query: 187 LDLVGLCALLVVLGVIPMVGF------DVFFQIFSHLKKLRMSRQDIRDEFKESEGDPHV 240 L+G +L L VI VGF D F+ + ++K+L+MS+ +I+ E+KE EG P + Sbjct: 177 TPLLG--QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEI 234 Query: 241 KGKIRQMQRAAAQRRMMEDVPKADVIVTNPTHYSVALQYDENKMSAPKVVAKGAGLIALR 300 K K RQ + R M E+V ++ V+V NPTH ++ + Y + P V K Sbjct: 235 KSKRRQFHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQT 294 Query: 301 IREIGAEHRVPTLEAPPLARALYRHAEIGQQIPGQLYAAVAEVLAWVWQLK 351 +R+I E VP L+ PLARALY A + IP + A AEVL W+ + Sbjct: 295 VRKIAEEEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQN 345
>INTIMIN#Intimin signature. Length = 939 Score = 248 bits (635), Expect = 1e-75 Identities = 126/444 (28%), Positives = 216/444 (48%), Gaps = 24/444 (5%) Query: 22 SFSLSLLLLTASGTICAQAQDPFDQNRL----PDLGMMPESHEGEKHFAEMAKAFGEASM 77 F S L L S + A N+L PD+ + + ++A A + + Sbjct: 118 PFEYSALPLLGSAPLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQL 177 Query: 78 KNNDLDTGEQARQFAFGQVRDVVSEQVNQQLESWLSAWGSASVDINVDNEGHFNGSRGSW 137 ++ L+ G+ A+ A G + Q + QL++WL +G+A V++ N F+GS + Sbjct: 178 QSRSLN-GDYAKDTALG----IAGNQASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDF 230 Query: 138 FIPLQDKQRYLTWSQLGLTQQTDGLVSNIGVGQRWAQDGWLLGYNTFYDNLLDENLQRAG 197 +P D ++ L + Q+G +N+G GQR+ +LGYN F D + R G Sbjct: 231 LLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLG 290 Query: 198 FGAEAWGEYLRLSANYYQPFADWQT--HTATLEQRMARGYDINAQMRLPFYQHINTSVSL 255 G E W +Y + S N Y + W + ++R A G+DI LP Y + + Sbjct: 291 IGGEYWRDYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMY 350 Query: 256 EQYFGDSVDLFDSGTGYHNPVALKLGLNYTPVPLLTMTAQHKQGESGVSQNNLGLTLNYR 315 EQY+GD+V LF+S NP A +G+NYTP+PL+TM ++ G + + Y+ Sbjct: 351 EQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQ 410 Query: 316 FGVPLKKQLAASEVAQSQSLRGSRYDTPQRNSLPTMEYRQRKTLTVFLATPPWDLTPGET 375 F P +Q+ V + ++L GSRYD QRN+ +EY+++ L++ + + T T Sbjct: 411 FDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERST 469 Query: 376 VALKLQVRSVHGIRHLSWQGDTQALSLTAG----TDTRSTEGWTIIMPAWDHREGAANRW 431 ++L V+S +G+ + W D AL G + ++S + + I+PA+ +G +N + Sbjct: 470 QKIQLIVKSKYGLDRIVW--DDSALRSQGGQIQHSGSQSAQDYQAILPAY--VQGGSNVY 525 Query: 432 RLSVVVEDEKGQRVSSNEITLALT 455 +++ D G SSN + L +T Sbjct: 526 KVTARAYDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.2 bits (177), Expect = 5e-17 Identities = 33/117 (28%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLVSMAPDISVVGEASNGEQGIDLAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A V SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKALSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALQQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 51.4 bits (123), Expect = 4e-09 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 17/123 (13%) Query: 473 SARFGFTVKLDYQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SHADDVVVTV 523 S +F ++ + Q+ P + VP L+Q E N +KH +++ Sbjct: 233 SIQFEDRLQFENQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKG 285 Query: 524 TQCGKQVKLKVQDNGCGVPENAERSNHYGMIIMRDRAQSLRG-DCQVRRRETGGTEVTVT 582 T+ V L+V++ G +N + S G+ +R+R Q L G + Q++ E G + Sbjct: 286 TKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 583 FIP 585 IP Sbjct: 346 LIP 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.026 Identities = 18/58 (31%), Positives = 28/58 (48%), Gaps = 1/58 (1%) Query: 128 TPFSTFIIISLLCGFAGANF-ASSMANISFFFPKQKQGGALGLNGGLGNMGVSVMQLV 184 + FS I+ + G A F A M ++ + PK+ +G A GL G + MG V + Sbjct: 101 SFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAI 158
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.1 bits (96), Expect = 7e-06 Identities = 17/48 (35%), Positives = 29/48 (60%) Query: 356 LTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 403 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 499 LSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 37.6 bits (87), Expect = 9e-05 Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 4/60 (6%) Query: 2 SFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 + A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>SYCECHAPRONE#Gram-negative bacterial type III secretion SycE chaperone signature. Length = 130 Score = 28.5 bits (63), Expect = 0.010 Identities = 16/34 (47%), Positives = 20/34 (58%), Gaps = 2/34 (5%) Query: 44 LKNQDPTNPLQNNELTTQLAQISTVSGIEKLNTT 77 L N+ P N L NN L TQL + V G E+L T+ Sbjct: 89 LWNRQPLNSLDNNSLYTQLEML--VQGAERLQTS 120
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.024 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 2e-15 Identities = 22/103 (21%), Positives = 46/103 (44%), Gaps = 7/103 (6%) Query: 6 TTTKGEQAKSQLIAAALAQFGEYGLHATT-RDIAALAGQNIAAITYYFGSKEDLYLACAQ 64 T + ++ + ++ AL F + G+ +T+ +IA AG AI ++F K DL+ + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 65 WIADFLGEKFRPHAEKAERLFSQPAPDRDAIRELILLACKNMI 107 +GE E + P +RE+++ ++ + Sbjct: 65 LSESNIGELEL---EYQAKFPGDPLS---VLREILIHVLESTV 101
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.0 bits (148), Expect = 2e-12 Identities = 48/286 (16%), Positives = 104/286 (36%), Gaps = 28/286 (9%) Query: 55 ASLNVDEGDAIKAGQVLGELDHAPYENALMQAKAGVSVAQAQYDLMLAGYRDEEIAQAAA 114 NV E + L + + ++N Q + + +A+ +LA E Sbjct: 175 YFQNVSEEEV-LRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 115 AVRQAQAAYDYAQNFYNRQQGLWKSRTISA--NDLENARSSRDQAQATLKSAQDKLSQYR 172 R + + + L + N+L +S +Q ++ + SA+++ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL-V 292 Query: 173 TGNREQDI----AQAKASLEQAKAQLAQAQLDLQDTTLIAPANGTLLTRAV-EPGSMLNA 227 T + +I Q ++ +LA+ + Q + + AP + + V G ++ Sbjct: 293 TQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT 352 Query: 228 GSTVLTLSLT-RPVWVRAYVDERNLSQTQPGRDILLYTDGRPDKPYH---GKIGFVSPTA 283 T++ + + V A V +++ G++ ++ + P Y GK+ ++ A Sbjct: 353 AETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA 412 Query: 284 EFTPKTVETPDLRTDLVYRLRIIVT-------DADDALRQGMPVTV 322 D R LV+ + I + + + L GM VT Sbjct: 413 --------IEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTA 450
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.6 bits (71), Expect = 0.009 Identities = 22/89 (24%), Positives = 29/89 (32%), Gaps = 21/89 (23%) Query: 294 PRFEDAFIDLLGGAGTSESPLGSILHTVEGTAGETVIEAQELTKKFGDFAATDHVNFVVQ 353 PR E + +LG P + Q + K HV V++ Sbjct: 548 PRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVME 590 Query: 354 RGEIFG----LLGPNGAGKSTTFKMMCGL 378 G F L G G GKST + GL Sbjct: 591 PGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.7 bits (66), Expect = 0.043 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 34 YVTGLVGPDGAGKTTLMRMLAGL 56 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 45.7 bits (108), Expect = 1e-07 Identities = 35/139 (25%), Positives = 60/139 (43%), Gaps = 5/139 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFVGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCATQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYL 333 P+ H D+ + I L Sbjct: 209 AARFLPLSHSIDLIRPIML 227
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 44.3 bits (104), Expect = 2e-06 Identities = 52/275 (18%), Positives = 85/275 (30%), Gaps = 34/275 (12%) Query: 366 PEPETPRQSFAPVAPTAVMTPP--QVQQPSAP-----------APQTSPAPLPASTSQVL 412 PE E Q V T + TP Q PS P AP PAP S + Sbjct: 983 PEVEKRNQ---TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 413 AARNQLQRAQGVTKTKK--SEPAAASRARPVNNSALERLASVSERVQARPTPSALETAPV 470 A N Q ++ V K ++ +E A + R + + + E A Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQN-----------REVAKEAKSNVKANTQTNEVAQS 1088 Query: 471 KKEAYRWKATTPVVQTKEVVATPKALKKALEHEKTPELAAKLAAEAIERDPWAAQVSQLS 530 E T +TKE K K +E EKT E K+ ++ + + V + Sbjct: 1089 GSET----KETQTTETKETATVEKEEKAKVETEKTQE-VPKVTSQVSPKQEQSETVQPQA 1143 Query: 531 LPKLVEQVALNAWKEQNGNAVCLHLRSTQRHLNSSGAQQKLAQALSDLTGTTVELTIVED 590 P +N + Q+ + +S+ Q + + VE Sbjct: 1144 EPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203 Query: 591 DNPAVRTPLEWRQAIYEEKLAQARESIIADNNIQT 625 T + + ++ S+ + T Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 27.3 bits (60), Expect = 0.041 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 116 QEFERRLLAMTQE--RKIRLAQATSLVEQQTLQKEVEIYEGRLARCRHALEKIENVLARL 173 E ER LA +E RK A + E + +KE+E + R E E LA L Sbjct: 125 AEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAAL 184 Query: 174 T 174 + Sbjct: 185 S 185
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 36.6 bits (84), Expect = 6e-04 Identities = 41/219 (18%), Positives = 81/219 (36%), Gaps = 18/219 (8%) Query: 92 RQKVAQAPEKMRQ-ATAALNALSDVDNDDEMRKTLSALSLRQLELRVA--QVLDDLQNSQ 148 R ++A+A EK R+ A AA A + + + + A + RQL+L A + L L Sbjct: 129 RLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALSEEA 188 Query: 149 NDLAAYNSQLVSLQTQPERVQNAMYTASQQI-------QQIRNRLDGNNVGEAALRPSQQ 201 + +L + Q++ ++ + T + ++ L G A + Sbjct: 189 KAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQASAKYK 248 Query: 202 VLLQAKQALLNAQID--------QQRKSLEGNTVLQDTLQKQRDYVTANSNRLEHQLQLL 253 L + + L D + + G +++ QKQ NR+ + + Sbjct: 249 ELDELVKKLSPRANDPLQNRPFFEATRRRVGAGKIREEKQKQVTASETRINRINADITQI 308 Query: 254 QEAVNSKRLTLTEKTAQEAISPDETARIQANPLVKQELD 292 Q+A++ A+ + + + Q N L Q D Sbjct: 309 QKAISQVSNNRNAGIARVHEAEENLKKAQNNLLNSQIKD 347
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 204 bits (519), Expect = 8e-69 Identities = 187/214 (87%), Positives = 199/214 (92%) Query: 1 MARKTKQQALETRQHILDVALRLFSQQGVSATSLAEIANAAGVTRGAIYWHFKNKSDLFS 60 MARKTKQ+A ETRQHILDVALRLFSQQGVS+TSL EIA AAGVTRGAIYWHFK+KSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELEIEYQAKFPDDPLSVLREILVHILEATVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELE+EYQAKFP DPLSVLREIL+H+LE+TVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMVVVQQAQRSLCLESYDRIEQTLKHCINAKMLPENLLTRRAAILMRSFISGLMENWLF 180 GEM VVQQAQR+LCLESYDRIEQTLKHCI AKMLP +L+TRRAAI+MR +ISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARAYVTILLEMYQLCPTLRASTVN 214 APQSFDLKKEAR YV ILLEMY LCPTLR N Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATN 214
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 43.3 bits (102), Expect = 1e-06 Identities = 33/216 (15%), Positives = 75/216 (34%), Gaps = 27/216 (12%) Query: 100 TYQATYDSAKGDLAKAQAAANIAELTVKRYQKLLGTQYISKQEYDQALADAQQATAAVVA 159 + Y A +L + + ++ + Q +++ ++ L +Q T + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSSV-TEGALVQNGQASALATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET-LMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA------------NGSLKQENGKAKVDLVTSDGIKFPQSGTLEFSDVT 266 + D + G L KV + D I+ + G + ++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYL-----VGKVKNINLDAIEDQRLGLVFNVIIS 427 Query: 267 VDQTTGSITLRAIFPNPDHTLLPGMFVRARLQEGTK 302 +++ S + I L GM V A ++ G + Sbjct: 428 IEENCLSTGNKNIP------LSSGMAVTAEIKTGMR 457 Score = 32.9 bits (75), Expect = 0.002 Identities = 24/133 (18%), Positives = 45/133 (33%), Gaps = 10/133 (7%) Query: 49 PLQITTELPGR-TVAYRIAEVRPQVSGIILKRNFV-EGSDIEAGVSLYQIDP-------A 99 ++I G+ T + R E++P + I+ K V EG + G L ++ Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIV-KEIIVKEGESVRKGDVLLKLTALGAEADTL 137 Query: 100 TYQATYDSAKGDLAKAQAAANIAELTVKRYQKLLGTQYISKQEYDQALADAQQATAAVVA 159 Q++ A+ + + Q + EL KL Y ++ L Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFST 197 Query: 160 AKAAVETARINLA 172 + +NL Sbjct: 198 WQNQKYQKELNLD 210
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3544), Expect = 0.0 Identities = 811/1033 (78%), Positives = 918/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISATYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDPISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPTELTKYQLTPVDVINAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ L KY+LTPVDVIN +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTDEFGKILLKVNQDGSQVRLRDVAKIELGGENYDVIAKFNGQPASGLGIKLATGANAL 300 + +EFGK+ L+VN DGS VRL+DVA++ELGGENY+VIA+ NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTATAIRAELKKMEPFFPPGMKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+L +++PFFP GMK++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 TEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPVAKGDHGEGKKGFFGWFNRLFDKSTHHYTDSVGNILRSTGR 540 SVLVALILTPALCAT+LKPV+ H E K GFFGWFN FD S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLLLYLIIVVGMAYLFVRLPSSFLPDEDQGVFLTMVQLPAGATQERTQKVLDEVTDYYLN 600 YLL+Y +IV GM LF+RLPSSFLP+EDQGVFLTM+QLPAGATQERTQKVLD+VTDYYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKANVESVFAVNGFGFAGRGQNTGIAFVSLKDWAERPGEKNKVEAITQRATAAFSQIKD 660 EKANVESVF VNGF F+G+ QN G+AFVSLK W ER G++N EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLFGEVAKYPDLLVGVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQL G A++P LV VRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSISDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS+SDIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDINDWYVRGSDGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D++ YVR ++G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MAMMEELASKLPSGIGYDWTGMSYQERLSGNQAPALYAISLIVVFLCLAALYESWSIPFS 900 MA+ME LASKLP+GIGYDWTGMSYQERLSGNQAPAL AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 VEATLEAVRMRLRPILMTSLAFMLGVMPLVISSGAGSGAQNAVGTGVLGGMVTATVLAIF 1020 VEATL AVRMRLRPILMTSLAF+LGV+PL IS+GAGSGAQNAVG GV+GGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 2e-04 Identities = 17/123 (13%), Positives = 38/123 (30%), Gaps = 28/123 (22%) Query: 300 TFTFEVDDSLSVLGNEEQLRSAISNLVYNAVNH----TPAGTHITVNWRRAAHGAEFCIQ 355 F +++ ++ + + + LV N + H P G I + + ++ Sbjct: 241 QFENQINPAIM---DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVE 297 Query: 356 DNGPGIAAEHIPRLTERFYRVDKARSRQTGGSGLGLAIVKHALNH---HESRLEIDSSPG 412 + G +G GL V+ L E+++++ G Sbjct: 298 NTGSLAL------------------KNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 413 KGT 415 K Sbjct: 340 KVN 342
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.8 bits (241), Expect = 2e-25 Identities = 34/149 (22%), Positives = 63/149 (42%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNKLNEPWPDLILLDWMLPGGSGLQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKREALTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPGSHRVMTGDSP 152 E L D + G S Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.021 Identities = 14/70 (20%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 149 KQQQLLHAIADYYQQQYREACQLRGERKLPVIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ Q+++ IA++Y +++ + E++ T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAIN-EKEAFECIYDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQHFPPADYI 218 + P DYI Sbjct: 191 ILNLPECDYI 200
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 46.0 bits (109), Expect = 7e-07 Identities = 31/198 (15%), Positives = 70/198 (35%), Gaps = 13/198 (6%) Query: 373 TQQSHDRAQLSQWQQQLLSDTRQRDALPPLTLDLTPQALAEARALHTRQRPLRHRLAALQ 432 TQ S +A+L Q + Q+LS + + + LP L L P + R L ++ Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL------IK 192 Query: 433 GQIIPKQKRQAQLQAAIARHHQEQTQYTQHLTDKRLSYKTKAQELADVRTICEQ----EA 488 Q Q ++ Q + + + E+ + + + L D ++ + + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 489 RIKDLESQRAHLQS--GQPCPLCGSTTHPAIAAYQALELSANQTRRDALEKEVKTLAEEG 546 + + E++ + ++A + +L + + L+K +T Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNI- 311 Query: 547 AALRGQLDALTQQLQRDE 564 L +L ++ Q Sbjct: 312 GLLTLELAKNEERQQASV 329
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.7 bits (124), Expect = 2e-09 Identities = 70/356 (19%), Positives = 122/356 (34%), Gaps = 35/356 (9%) Query: 5 IFSLALGTFGLGMAEFGIMGVLTELARDVGITIPAAGH---MISFYAFGVVLGAPVMALF 61 + ++AL G+G+ IM VL L RD+ + H +++ YA APV+ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 62 SSRFSLKHILLFLVTLCVMGNAIFTFSSSYLMLAVGRLVSGFPHGAFFGVGAIVLSKIIR 121 S RF + +LL + + AI + +L +GR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 122 PGKVTAAVAGMVSGMTVANLVGIPVGTYLSQEFSWRYTFLLIAVFNIAVLTAIFFWVPDI 181 G A G +S +V PV L FS F A N F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 182 RDKAQGSLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYIKPFMMYI 229 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 230 SGFSETSMTFIMMLVGLGM---VLGNLLSGKLSGRYTPLRIAVVTDLIIVLSLMALFFFS 286 F + T + L G+ + +++G ++ R R ++ ++ + Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLG---MIADGTGYILLA 295 Query: 287 GYKTASLTFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAIG 340 + F + + P +L E G G +A +L S +G Sbjct: 296 FATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVG 351
>PF06291#Lambda prophage Bor protein Length = 102 Score = 30.0 bits (67), Expect = 0.002 Identities = 21/68 (30%), Positives = 30/68 (44%), Gaps = 11/68 (16%) Query: 28 VNDKEIICSPDESNTHTFVILEGVVSLVRGDKVLIGIVQAPFIFGLADGVAKKEAQYKLI 87 V +K +P E+ TH F VS + K V A I G A+ V K E Q + Sbjct: 29 VGNKPTAVTPKETITHHFF-----VSGIGQKKT----VDAAKICGGAENVVKTETQQTFV 79 Query: 88 AESGCIGY 95 +G +G+ Sbjct: 80 --NGLLGF 85
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 121 bits (304), Expect = 5e-30 Identities = 99/436 (22%), Positives = 166/436 (38%), Gaps = 59/436 (13%) Query: 597 TYSANGEADNSYTDNVVA---ATGNYKVRIDNATGAGSVADYKGNELIRVNDVNTDATFS 653 + N AD +D +V A+G +++ + N+ GS L+ + + ATF+ Sbjct: 483 LFRMNVFADLGLSDKLVVMQDASGQHRLWVRNS---GSEPASANTLLLVQTPLGSAATFT 539 Query: 654 AAN---KADLGAYTYQAKQEGNTV------------------------------------ 674 AN K D+G Y Y+ GN Sbjct: 540 LANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPAPQ 599 Query: 675 VLEQMELTDYANMALSIP--SANTNIWNLEQDTVGTRLTNARHGLADNGGAWVSYFGGNF 732 EL+ AN A++ + +W E + + RL R D GGAW F Sbjct: 600 PPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRL-NPDAGGAWGRGFAQRQ 658 Query: 733 NGDNGTIN-YDQDVNGIMVGVDTKVDGNNAKWIVGAAAGFAKGDLS---DRTGQVDQDSQ 788 DN +DQ V G +G D V +W +G AG+ +GD D G D Sbjct: 659 QLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTD---- 714 Query: 789 SAYIYSSARFANN--IFVDGNLSYSHFNNDLSANMSDGTYVDGNTSSDAWGFGLKLGYDW 846 S ++ A + + ++D L S ND SDG V G + G L+ G + Sbjct: 715 SVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRF 774 Query: 847 KLGDAGYVTPYGSVSGLFQSGDDYQLSNNMKVDGQSYDSMRYEIGVDAGYTFTYSEDQAL 906 D ++ P ++ G Y+ +N ++V + S+ +G++ G + + + Sbjct: 775 THADGWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGGRQV 834 Query: 907 TPYFKLAYVYD-DSNNDADVNGDSIDNGVEGSAVRVGLGTQFSFTKNFSAYTDANYLGGG 965 PY K + + + D NG + + G+ +GLG + + S Y Y G Sbjct: 835 QPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYSKGP 894 Query: 966 DVDQDWSANVGVKYTW 981 + W+ + G +Y+W Sbjct: 895 KLAMPWTFHAGYRYSW 910
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 32.3 bits (73), Expect = 0.003 Identities = 19/69 (27%), Positives = 29/69 (42%) Query: 254 DVLREIRERTELPLGAYQVSGEYAMIKFAAMAGAIDEEKVVLESLGSIKRAGADLIFSYF 313 + E+ + +L L QV G A F +D E L I+ A +IF+ Sbjct: 466 NQFLELEKTKQLRLDTDQVYGNIATYNFENGRVRVDTGSNWSEVLPQIQETTARIIFNGK 525 Query: 314 ALDLAEKNI 322 L+L E+ I Sbjct: 526 DLNLVERRI 534
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 345 bits (886), Expect = e-115 Identities = 122/379 (32%), Positives = 191/379 (50%), Gaps = 51/379 (13%) Query: 191 DALDMTRLTRR--QRVDYPPGKGLQTRYELGDIRGQSPQMEQLRQTITLYARSRAAVLIQ 248 D ++ + R P K + + G+S M+++ + + ++ ++I Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMIT 166 Query: 249 GETGTGKELAAQAIHQTFFHRQPHRQNKPSPPFVAVNCGAITESLLEAELFGYEEGAFTG 308 GE+GTGKEL A+A+H R+N P FVA+N AI L+E+ELFG+E+GAFTG Sbjct: 167 GESGTGKELVARALHD-----YGKRRNGP---FVAINMAAIPRDLIESELFGHEKGAFTG 218 Query: 309 SRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVLEEKAVTRVGGHQPIPVDVRVIS 368 ++ G FE A GGTLFLDEIG+MP+ QTRLLRVL++ T VGG PI DVR+++ Sbjct: 219 AQTR-STGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVA 277 Query: 369 ATHCDLDREIMQGRFRPDLFYRLSILRLTLPPLRERQADILPLAENFLKQSLAAMEIPFT 428 AT+ DL + I QG FR DL+YRL+++ L LPPLR+R DI L +F++Q + Sbjct: 278 ATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLD-- 334 Query: 429 ESIRHGLTQCQPLLLAWRWPGNIRELRNMMERLALFLS---------------------- 466 ++ + L+ A WPGN+REL N++ RL Sbjct: 335 --VKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPI 392 Query: 467 ----VDPAPTLDRQFMRQLLPELMVNTAELTPST---------VDAHALQDVLARFNGDK 513 Q + + + + + + P + ++ + L G++ Sbjct: 393 EKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQ 452 Query: 514 TAAARYLGISRTTLWRRLK 532 AA LG++R TL ++++ Sbjct: 453 IKAADLLGLNRNTLRKKIR 471
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 33.6 bits (76), Expect = 7e-04 Identities = 23/70 (32%), Positives = 33/70 (47%), Gaps = 8/70 (11%) Query: 258 KGERQGRQVGLEEGLAEGLEKGLEKGQHVAALRIAR--------QMLADGLDRETVQRFT 309 +G +QG + G +EGLA+GLE+GL + + A AR Q D LD R Sbjct: 62 EGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLM 121 Query: 310 GLTAEELQDV 319 + E + V Sbjct: 122 QMALEAARQV 131 Score = 30.9 bits (69), Expect = 0.005 Identities = 16/47 (34%), Positives = 26/47 (55%) Query: 238 PHTKERLMTLIERIRAADRRKGERQGRQVGLEEGLAEGLEKGLEKGQ 284 P +++L L + + G +GRQ G ++G EGL +GLE+G Sbjct: 38 PSLEQQLAQLQMQAHEQGYQAGIAEGRQQGHKQGYQEGLAQGLEQGL 84
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 47.6 bits (113), Expect = 5e-08 Identities = 35/141 (24%), Positives = 64/141 (45%), Gaps = 5/141 (3%) Query: 58 SLYLAGGMALQWLLGPLSDRIGRRPVLIAGALIFTLACAATLLTTSMTQFLV-ARFVQGT 116 L + G A+ G LSD++G + +L+ G +I + S L+ ARF+QG Sbjct: 59 MLTFSIGTAV---YGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGA 115 Query: 117 SICFIATVGYVTVQEAFGQTKAIKLMAIITSIVLVAPVIGPLSGAALMHFVHWKVLFGII 176 + V V + K +I SIV + +GP G + H++HW L +I Sbjct: 116 GAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL-LI 174 Query: 177 AVMGLLALCGLLLAMPETVQR 197 ++ ++ + L+ + + V+ Sbjct: 175 PMITIITVPFLMKLLKKEVRI 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 83/396 (20%), Positives = 141/396 (35%), Gaps = 31/396 (7%) Query: 9 PRHPIFTALFGMMVLTLGMGVGRFLYTPMLPVMLAEKQLTFNQLSWIASANYAGYLAGSL 68 P P+ L + + +G+G L P+LP +L + + N ++ A Y Sbjct: 3 PNRPLIVILSTVALDAVGIG----LIMPVLPGLLRDLVHS-NDVTAHYGILLALYALMQF 57 Query: 69 LFSFGLFHLPSRL--RPMLLASAVATGILILSMAIFTQPAVVMLVRFLAGVASAGMMIFG 126 + L L R RP+LL S + MA V+ + R +AG+ A + G Sbjct: 58 ACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG 117 Query: 127 SMI-----VLHHTRHPFVIAALFSGVGAGIALGNEYVIGGLHYALSAHSLWLGAGALAGI 181 + I RH ++A F G G+ G V+GGL S H+ + A AL G+ Sbjct: 118 AYIADITDGDERARHFGFMSACF---GFGMVAGP--VLGGLMGGFSPHAPFFAAAALNGL 172 Query: 182 LLLIVAMLIPPRAHALPPAPLARIENQPMPWWQLA-LLYGFAGFGYIIVATYLPLMAKSA 240 L L+P +H PL R P+ ++ A + A + L +A Sbjct: 173 NFLTGCFLLPE-SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAA 231 Query: 241 GSPLLTAHL--WSLVGLAIIPGCFGWLWA----------AKHWGVLPCLTANLLIQSACV 288 + W + I FG L + A G L ++ Sbjct: 232 LWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY 291 Query: 289 LLSLASDSLLLLILSSIGFGATFMGTTSLVMPLARQLSAPGNINLLGLVTLTYGIGQILG 348 +L + + + + +G +L L+RQ+ L G + + I+G Sbjct: 292 ILLAFATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVG 351 Query: 349 PLAASLSGNGAPAIINATLCGAAALFFAALISAAQQ 384 PL + + N A A + + A ++ Sbjct: 352 PLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 36.6 bits (85), Expect = 1e-04 Identities = 32/129 (24%), Positives = 49/129 (37%), Gaps = 33/129 (25%) Query: 26 CDVLLANGKIIAVGADIPGDIVPDCT--------VINLSGRMLCPGFIDQHVHLIGG--- 74 D+ L +G+I A+G D+ P T VI G+++ G +D H+H I Sbjct: 86 ADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQI 145 Query: 75 ------------GGEAGP------TTRTP-EVSLSRLTEA--GITTVVGLLGTDSVSRHP 113 GG GP TT TP ++R+ EA + G + S P Sbjct: 146 EEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNAS-LP 204 Query: 114 ASLLAKTRA 122 +L+ Sbjct: 205 GALVEMVLG 213
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 29.2 bits (65), Expect = 0.030 Identities = 15/64 (23%), Positives = 25/64 (39%), Gaps = 7/64 (10%) Query: 130 PPPPPPVVAKRVESAPRPTEPARNPFKSSDDRLTGVTSSNTVTRPAARASAGAGDKVVIA 189 P P P K+VE R +P + S + + RP + + A K V + Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFE-------NTAPARPTSSTATAATSKPVTS 152 Query: 190 IDAG 193 + +G Sbjct: 153 VASG 156
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 32.1 bits (73), Expect = 0.005 Identities = 39/163 (23%), Positives = 60/163 (36%), Gaps = 13/163 (7%) Query: 80 CVFILVGAAAQYFILTYGIIIDRSMIANMMDTTPAETFALM-TPQMVLTLG---LSGVLA 135 CV +V A +L+ + +M P T LM V T G L +LA Sbjct: 177 CVLTVVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLA 236 Query: 136 AVIAFWVKIRPATPRLRSGLYRLASVLISILLVILVAAFFYKDYASLFRNNKQLIKALSP 195 +AF V +R R+ L LI + L A + + + L + L++A+ Sbjct: 237 GFMAFRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRI 296 Query: 196 SNSIVASWSWYSHQRLANLPLVRIGEDAHRN--------PLML 230 S V S + H+ VR G H+ P+M Sbjct: 297 S-GDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMR 338
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 8e-24 Identities = 46/144 (31%), Positives = 69/144 (47%), Gaps = 1/144 (0%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLH 61 IL+ +DD + L A GY S A + +G L+V D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLTRIRQKKYTLPVLILTARDTLNDRISGLDVGADDYLVKPFALEELHARI-RALLRRHN 120 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 NQGESELTVGNLTLNIGRHQAWRD 144 + E + +GR A ++ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQE 148
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 2e-04 Identities = 38/182 (20%), Positives = 78/182 (42%), Gaps = 34/182 (18%) Query: 184 ARLDQMMDSVSQLLQLARVGQSFSSGNYQEVKLLEDV-ILPSYDELNTM-LETR-QQTLL 240 + +M+ S+S+L++ S N ++V L +++ ++ SY +L ++ E R Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 241 LPESAADVVVRGDATLLRMLLRNLVENAHRY----SPEGTHITIHISADPDAI-MAVEDE 295 + + DV V ML++ LVEN ++ P+G I + + D + + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 296 GPGIDESKCGKLSEAFVRMDSRYGGIGLGLSIV-SRITQLHQGQFFLQNRTERTGTRAWV 354 G + + G GL V R+ L+ + ++ ++ A V Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 355 ML 356 ++ Sbjct: 346 LI 347
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.5 bits (100), Expect = 2e-06 Identities = 53/284 (18%), Positives = 104/284 (36%), Gaps = 40/284 (14%) Query: 85 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYATIGIWAPILLLLCKMAQGFSVGGE 144 G L D++GR+ +L +++ ++ + P +W +L + ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 145 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEENFLEWGW 200 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 201 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKHWRS 260 PFF A L + L K E+ P SF+ + Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFRWARGMTVVA 213 Query: 261 LLSCIGLVIATNVTYYMLLTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVMGLLS 319 L + ++ + + + H+ G+ + ++ L + G ++ Sbjct: 214 ALMAVFFIM--QLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 320 DRFGRRPFVIMGSIA-LFALAIPAFILINSNVIGLIFAGLLMLA 362 R G R +++G IA + AF + F +++LA Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFA----TRGWMAFPIMVLLA 311 Score = 38.7 bits (90), Expect = 5e-05 Identities = 37/164 (22%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 286 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVIMGSIALFALAIPAFI 344 L H+ + +G+L+ + A+M PV+G LSDRFGRRP ++ ++L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLL---VSLAGAAVDYAI 89 Query: 345 LINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIR---YSALAAAFNISVLIAG 401 + + + +++ G ++A I V + + + R + ++A F ++AG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 402 LTPTLAAWLVESSQDLMMPAYYLMVIAVIGLITGI-SMKETANR 444 P L + S P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFS--PHAPFFAAAALNGLNFLTGCFLLPESHKG 187
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 2e-04 Identities = 21/86 (24%), Positives = 33/86 (38%), Gaps = 9/86 (10%) Query: 51 LALRNGEVVGMISLHMQFHLHHANWIG--EIQELVVLPQMRGQKVGSQLLAWAEEEARQA 108 L +G I + +NW G I+++ V R + VG+ LL A E A++ Sbjct: 69 LYYLENNCIGRIKIR-------SNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKEN 121 Query: 109 GAELTELSTNIKRRDAHRFYVREGYK 134 L T A FY + + Sbjct: 122 HFCGLMLETQDINISACHFYAKHHFI 147
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.1 bits (65), Expect = 0.040 Identities = 12/58 (20%), Positives = 24/58 (41%), Gaps = 1/58 (1%) Query: 16 MAINVVIIAMQLLLAYFYTDIYGLSAADVGVLFVVVRMIDAII-DPAMGVLTDKLNTR 72 I + ++ Y D++ LS A++G + + + II G+L D+ Sbjct: 266 GIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPL 323
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.4 bits (63), Expect = 0.034 Identities = 32/140 (22%), Positives = 58/140 (41%), Gaps = 27/140 (19%) Query: 10 SRAAIAATAMASALLLIKIFAWWYTGSVSILAALVD-SLVDIAASLTNLLVVRYSLQPAD 68 ++AA+A + + W S+L AL +L +A + ++V +L P+ Sbjct: 123 TKAALAGAGIGVVAAALGYTQWL-----SLLYALPVIALTGLAFASLGMVVT--ALAPSY 175 Query: 69 DEHTFGHGKAESLAALAQSMFISGSAL--------------FLFLTSIQNLIKPTPMNDP 114 D F ++L + +F+SG+ FL L+ +LI+P + P Sbjct: 176 DYFIF----YQTLV-ITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHP 230 Query: 115 GVGIGVTVIALICTIILVTF 134 V + V AL I++ F Sbjct: 231 VVDVCQHVGALCIYIVIPFF 250
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 31.7 bits (72), Expect = 0.005 Identities = 31/161 (19%), Positives = 55/161 (34%), Gaps = 8/161 (4%) Query: 186 AQLSYIFAATLFSLFGLLFMWLCYAGVKERYVEVKPVDKAQKPGLLQSFRAIAGNRPLFI 245 + AA L L L +L K E +P+ + + L SFR G + Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKG---ERRPLRR-EALNPLASFRWARGMTVVAA 214 Query: 246 LCIANLCTLGAFNVKLAIQVYYTQYVLN-DPILLSWM--GFFSMGCIFIGVFLMPGAVRR 302 L V A+ V + + + D + F + + + R Sbjct: 215 LMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLA-QAMITGPVAAR 273 Query: 303 FGKKKVYIGGLLIWVAGDLLNYFFGGGSVSFVAFSCLAFFG 343 G+++ + G++ G +L F G ++F LA G Sbjct: 274 LGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG 314
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 178 bits (454), Expect = 1e-50 Identities = 100/448 (22%), Positives = 170/448 (37%), Gaps = 87/448 (19%) Query: 4 NLRNIAIIAHVDHGKTTLVDKLLQQSGTFDARAETQE--RVMDSNDLEKERGITILAKNT 61 + NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAHGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIIYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIIDHVPAPDVDLDGPLQMQISQLDYNNYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + L ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLTHLGLERIDSDIAEAGDIIAITGLG-ELN--ISDTICDPQNVEALPALSVDE 304 K+ ++ T + E D A +G+I+ + +LN + DT PQ + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLPQR----ERIENPL 343 Query: 305 PTVSMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGEL 364 P + + + D L LR +S G++ Sbjct: 344 PLLQTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKV 394 Query: 365 HLSVLIENMRRE-GFELAVSRPKVIFRE 391 + V ++ + E+ + P VI+ E Sbjct: 395 QMEVTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.034 Identities = 33/189 (17%), Positives = 71/189 (37%), Gaps = 39/189 (20%) Query: 171 IIEQADRLRNLVDRL-------LGPQHPGMHIT--ESIHKVAERVVALVSMELPDNVRLI 221 I+E + R ++ L L ++ + + V + + L S++ D ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYS-NARQVSLADELTVV-DSYLQLASIQFEDRLQFE 243 Query: 222 RDYDPSLPELPHDPEQIEQVLL-NIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLA 280 +P++ ++ P + Q L+ N +++ + L P+GG+I L+ Sbjct: 244 NQINPAIMDVQV-PPMLVQTLVENGIKHGIAQL-PQGGKILLKGT------KDNGTVT-- 293 Query: 281 ARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHAGK---IEFTSWPG 337 ++VE+ G + ++ TG GL R + G I+ + G Sbjct: 294 --LEVENTGSLALKNTKE------------STGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 338 HTEFSVYLP 346 V +P Sbjct: 340 KVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 597 bits (1540), Expect = 0.0 Identities = 204/478 (42%), Positives = 299/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGNEVLAALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNIEVNGPTTDMIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLERRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L++ + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRIHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETETALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFEASAPDSPSHLPPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>SECA#SecA protein signature. Length = 901 Score = 28.3 bits (63), Expect = 0.018 Identities = 14/74 (18%), Positives = 27/74 (36%) Query: 11 KAFGKQRRKTREELNQEARDRKRLKKHRGHAPGSRAAGGNSASGGGNQNQQKDPRIGSKT 70 K + + EE+ + + R+ + +SA+ Q + ++G Sbjct: 824 STLSKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRND 883 Query: 71 PVPLGVTEKVTQQH 84 P P G +K Q H Sbjct: 884 PCPCGSGKKYKQCH 897