>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 32.1 bits (73), Expect = 0.007 Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 2/60 (3%) Query: 119 EVTEILVKVGDKV-EAEQSLITVEGDKASMEVPAPFAGTVKEIKVN-VGDKVSTGSLIMV 176 E+ + L + D + L E + + + AP + V+++KV+ G V+T +MV Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 31.7 bits (72), Expect = 0.008 Identities = 16/63 (25%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 26 DKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAP 85 + V +T G S E+ + IVKEI V G+ + G +++ + AD Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK 138 Query: 86 AQA 88 Q+ Sbjct: 139 TQS 141 Score = 30.6 bits (69), Expect = 0.019 Identities = 14/60 (23%), Positives = 28/60 (46%), Gaps = 2/60 (3%) Query: 220 EVTEVMVKVGDKVAA-EQSLITVEGDKASMEVPAPFAGVVKELKVN-VGDKVKTGSLIMI 277 E+ + + + D + L E + + + AP + V++LKV+ G V T +M+ Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Score = 29.8 bits (67), Expect = 0.035 Identities = 20/95 (21%), Positives = 35/95 (36%), Gaps = 3/95 (3%) Query: 230 DKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMIFEVEGAAPAAAP 289 + VA +T G S E+ +VKE+ V G+ V+ G +++ GA A Sbjct: 81 EIVATANGKLTHSGR--SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE-ADTL 137 Query: 290 AKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAEND 324 Q + A + + + + E D Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPD 172
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.2 bits (65), Expect = 0.022 Identities = 26/99 (26%), Positives = 39/99 (39%), Gaps = 20/99 (20%) Query: 110 MVKIEGGEWL----VETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAGDQL-L 164 V +E G L + V L AV GL P +V + D++G L Sbjct: 176 TVTLEPGRALDEGQISAVVHLVSSAVA-----GLPPGNVTLV---------DQSGHLLTQ 221 Query: 165 SDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIG 203 S+ + AQL V + +RI L+ P++G G Sbjct: 222 SNTSGRDLNDAQLKFANDVESRIQRRIEAILS-PIVGNG 259
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 791 bits (2045), Expect = 0.0 Identities = 270/870 (31%), Positives = 431/870 (49%), Gaps = 40/870 (4%) Query: 14 RIATFCALLYCNTAFSAELVEYDHTFLMGQNASNIDLSRYSEGNPAIPGVYDVSVYVNDQ 73 R+ CA SAE + ++ FL + DLSR+ G PG Y V +Y+N+ Sbjct: 29 RLFVACAFAAQAPLSSAE-LYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNG 87 Query: 74 PIINQSITFVAIEGKKNAQACITLKNLLQFHINSPDINNEKAVLLARDETLGNCLNLTEI 133 + + +TF + ++ C+T L +N+ + LLA D C+ LT + Sbjct: 88 YMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASV--SGMNLLADDA----CVPLTSM 141 Query: 134 IPQASVRYDVNDQRLDIDVPQAWVMKNYQNYVDPSLWENGINAAMLSYNLNGYHSETP-G 192 I A+ + DV QRL++ +PQA++ + Y+ P LW+ GINA +L+YN +G + G Sbjct: 142 IHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIG 201 Query: 193 RKNESIYAAFNGGMNLGAWRLRASGNYNWMTDSGS-----NYDFKNRYVQRDIASLRSQL 247 + Y G+N+GAWRLR + +++ + S + N +++RDI LRS+L Sbjct: 202 GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRL 261 Query: 248 ILGESYTTGETFDSVSIRGIRLYSDSRMLPPTLASFAPIIHGVANTNAKVTITQGGYKIY 307 LG+ YT G+ FD ++ RG +L SD MLP + FAP+IHG+A A+VTI Q GY IY Sbjct: 262 TLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIY 321 Query: 308 ETTVPPGAFVIDDLSPSGYGSDLIVTIEESDGSKRTFSQPFSSVVQMLRPGVGRWDISGG 367 +TVPPG F I+D+ +G DL VTI+E+DGS + F+ P+SSV + R G R+ I+ G Sbjct: 322 NSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAG 381 Query: 368 QVLKDD-IQDEPNLFQASYYYGLNNYLTGYTGIQITDNNYTAGLLGLGLNT-SVGAFSFD 425 + + Q++P FQ++ +GL T Y G Q+ D Y A G+G N ++GA S D Sbjct: 382 EYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLAD-RYRAFNFGIGKNMGALGALSVD 440 Query: 426 VTHSNVRIPDDKTYQGQSYRVSWNKLFEETSTSLNIAAYRYSTQNYLGLNDALTLIDEVK 485 +T +N +PDD + GQS R +NK E+ T++ + YRYST Y D Sbjct: 441 MTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGY 500 Query: 486 HPE-----QDLEPKSMRNYSRM---KNQVTVSINQPLKFEKKDYGSFYLSGSWSDYWASG 537 + E ++PK Y+ + ++ +++ Q L + YLSGS YW + Sbjct: 501 NIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL----GRTSTLYLSGSHQTYWGTS 556 Query: 538 QNRSNYSIGYSNSTSWGSYSVSAQRSWNE-DGDTDDSVYLSFTIPIEKLLGTEQRTS-GF 595 + G + + ++++S + N D + L+ IP L ++ ++ Sbjct: 557 NVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRH 616 Query: 596 QSIDTQISSDFKGNNQLNVSSSGYS-DNARVSYSVNTGYTMNKASKDLSYVGGYASYESP 654 S +S D G G ++ +SYSV TGY S +Y Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 655 WGTLAGSISANSDNSRQVSLSTDGGFVLHSGGLTFSNDSFSDSDTLAVVQAPGAQGARIN 714 +G S + D +Q+ GG + H+ G+T +DT+ +V+APGA+ A++ Sbjct: 677 YGNANIGYSHSDDI-KQLYYGVSGGVLAHANGVTLGQPL---NDTVVLVKAPGAKDAKVE 732 Query: 715 YGNST-IDRWGYGVTSALSPYHENRIALDINDLENDVELKSTSAVAVPRQGSVVFADFET 773 D GY V + Y ENR+ALD N L ++V+L + A VP +G++V A+F+ Sbjct: 733 NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA 792 Query: 774 VQGQSAIMNITRSDGKNIPFAADIYDEQGNVIGNVGQGGQAFVRGIEQQGNISIKWLEQS 833 G +M +T + K +PF A + E G V GQ ++ G+ G + +KW E+ Sbjct: 793 RVGIKLLMTLTH-NNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEE 851 Query: 834 KPVSCLAHYQQSPEAEKIAQSIILNGIRCQ 863 C+A+YQ P + L+ C+ Sbjct: 852 NA-HCVANYQL-PPESQQQLLTQLSA-ECR 878
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 511 bits (1318), Expect = 0.0 Identities = 296/296 (100%), Positives = 296/296 (100%) Query: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA Sbjct: 1 MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVA 60 Query: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR Sbjct: 61 DTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGR 120 Query: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT Sbjct: 121 GFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLT 180 Query: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH Sbjct: 181 TLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDH 240 Query: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA Sbjct: 241 DNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMHFVRVLDNAIGGKA 296
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 34.3 bits (78), Expect = 4e-04 Identities = 12/55 (21%), Positives = 28/55 (50%), Gaps = 4/55 (7%) Query: 186 NDYYRKVKELRAKNQITLPVILKNERQINVFLRT----EDIDLINVINEETLLQQ 236 + ++ EL A N T+ +K ++N+ +R D + I V +E+++++ Sbjct: 589 QNIKNQLAELNATNIYTVLDKIKLNAKMNILIRDKRFHYDRNNIAVGADESVVKE 643
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 26.9 bits (59), Expect = 0.011 Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 45 AVYKDHPLQGSWKGYRDAHVEPD 67 +VYK + + G+ A V Sbjct: 153 SVYKAFSDRVTLPGFNSAKVTSL 175
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 6e-05 Identities = 28/127 (22%), Positives = 48/127 (37%), Gaps = 17/127 (13%) Query: 119 DTLRALLDNNI---------VPVINENDAVATAEIKVGDNDNLSALAAILAGADKLLLLT 169 +T++ L++ + VPVI E+ + E V D D A AD ++LT Sbjct: 177 ETIKKLVERGVIVIASGGGGVPVILEDGEIKGVE-AVIDKDLAGEKLAEEVNADIFMILT 235 Query: 170 DQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKLQAA-DVACRAG 228 D G + + +++V +++ + G M K+ AA G Sbjct: 236 DVNGAALY--YGTEKEQWLREV-KVEELRKYYEEG---HFKAGSMGPKVLAAIRFIEWGG 289 Query: 229 IDTIIAA 235 IIA Sbjct: 290 ERAIIAH 296 Score = 30.2 bits (68), Expect = 0.013 Identities = 16/76 (21%), Positives = 33/76 (43%), Gaps = 13/76 (17%) Query: 4 SQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQ----LHAAGHRIVIVTSG-------- 51 + +V+ LG + L ++ + +++ VR+ A+ + A G+ +VI Sbjct: 2 GKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLL 61 Query: 52 -AIAAGREHLGYPELP 66 + AG+ G P P Sbjct: 62 LHMDAGQATYGIPAQP 77
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.023 Identities = 10/30 (33%), Positives = 16/30 (53%) Query: 34 MVTLLGPSGCGKTTILRLVAGLEKPSEGQI 63 V L G G GK+T++ + GL+ S+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHF 627
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.9 bits (57), Expect = 0.035 Identities = 7/45 (15%), Positives = 16/45 (35%), Gaps = 1/45 (2%) Query: 4 KRYPEEFKTEAVKQVVDL-GYSVASVATRLDITTHSLYAWIKKYG 47 R E + + + + A L + ++L I++ G Sbjct: 430 DRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG 474
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 63.3 bits (154), Expect = 3e-12 Identities = 38/316 (12%), Positives = 93/316 (29%), Gaps = 33/316 (10%) Query: 487 TLNLNSLWSKLGTFSISYNDDRRYNSHYYTADYYQNVYSGTFGSLGLRAGIQRYNNGDSN 546 L + + T +S + Y + +Q + F + N Sbjct: 530 QLTVTQQLGRTSTLYLSG-SHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQK 588 Query: 547 ANTGKYIALDLSLPLGNWFSAGMTHQNGYTMANLSARKQFDEGT------------IRTV 594 + +AL++++P +W + Q + A+ S + + Sbjct: 589 -GRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNL 647 Query: 595 GANLSRAISGDTGDDKTLSGGAYAQFDARYASGTLNVNSAADGYVNTNLTANGSVGWQGK 654 ++ +G + +G A + Y + + S +D +G V Sbjct: 648 SYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGY-SHSDDIKQLYYGVSGGVLAHAN 706 Query: 655 NIAASGRTDGNAGVIFNTGLED---DGQISAKINGRIFPLNGKRNYLPLSPYGRYEVELQ 711 + + ++ G +D + Q + + R G + Y V L Sbjct: 707 GVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR-----GYAVLPYATEYRENRVALD 761 Query: 712 NSKNSLDSYDIVSGRKSRLTLYPGNVAVIEPEVKQMVTVSGRIRAEDGTLLANARINNHI 771 + + + D+ + + G + E + + + + + + L A + Sbjct: 762 TNTLADN-VDLDNAVA-NVVPTRGAIVRAEFKARVGIKLLMTLTHNNKPLPFGAMV---- 815 Query: 772 GRTRTDENGEFVMDVD 787 T E+ + V Sbjct: 816 ----TSESSQSSGIVA 827
>INTIMIN#Intimin signature. Length = 939 Score = 391 bits (1006), Expect = e-132 Identities = 113/257 (43%), Positives = 146/257 (56%), Gaps = 8/257 (3%) Query: 41 PVMAARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDS-----DATRNF 95 P++AA +L+ + VT N + ++AA L SQ S D ++ Sbjct: 131 PLVAAGGVAGHTNKLTKMSPDVTKSNMTDDKALNYAAQQAASLGSQLQSRSLNGDYAKDT 190 Query: 96 ITGMATAKANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAI 155 G+A +A+ ++Q WL YGTA V L +F SSL+ L P YD+ + F Q Sbjct: 191 ALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD--GSSLDFLLPFYDSEKMLAFGQVGA 248 Query: 156 HRTDDRTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGY 215 D R +N+G G R F M G N FID D S +TR+G+G EYWRDY K S NGY Sbjct: 249 RYIDSRFTANLGAGQRFFLPE-NMLGYNVFIDQDFSGDNTRLGIGGEYWRDYFKSSVNGY 307 Query: 216 IRASGWKKSPDIEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQ 275 R SGW +S + +DY ERPANG+DIR GYLP++P LGA LMYEQYYGD V LF DK Q Sbjct: 308 FRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDNVALFNSDKLQ 367 Query: 276 KDPHAISAEVTYTPVPL 292 +P A + V YTP+PL Sbjct: 368 SNPGAATVGVNYTPIPL 384
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.016 Identities = 12/42 (28%), Positives = 19/42 (45%) Query: 3 RQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN 44 RQ IL L S+ +IA+ +G +R I F++ Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKD 54
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1369 bits (3546), Expect = 0.0 Identities = 802/1033 (77%), Positives = 915/1033 (88%), Gaps = 1/1033 (0%) Query: 1 MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDT 60 M NFFI RPIFAWV+AII+M+AG LAIL+LPVAQYPTIAPPAV++SA+YPGADA+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQ 120 VTQVIEQNMNGIDNLMYMSS SDS G+V ITLTF+SGTD DIAQVQVQNKLQLA PLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGS 180 EVQQQG+SVEKSSSS+LMV G ++ + TQ+DISDYVA+N+KD +SR +GVGDVQLFG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRL 240 QYAMRIW++ + LNK++LTPVDVI +K QN Q+AAGQLGGTP + GQQLNASIIAQTR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 TSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANAL 300 + EEFGK+ L+VN DGS V L+DVA++ELGGENY++IA NG+PA+GLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQ 360 DTA AI+A+LA+++PFFP G+K++YPYDTTPFV++SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTFA+LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMAL 480 E+ LPPKEAT KSM QIQGALVGIAMVLSAVF+PMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGR 540 SVLVALILTPALCAT+LKP++ H E K GFFGWFN F+ S +HYT+SVG IL STGR Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLT 600 YL++Y +IV GM LF+RLPSSFLP+EDQGVF+TM+QLPAGATQERTQKVL++VT YYL Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKD 660 EK NVESVF VNGF F+G+ QN G+AFVSLK W +R G+EN EA+ RA +I+D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNG 720 V FN+PAIVELGTATGFDFELIDQAGLGH+ LTQARNQLL AA+HP L SVRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 721 LEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYR 780 LEDT QFK+++DQEKAQALGVS++DIN T+ A GG+YVNDFIDRGRVKK+YV ++AK+R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 781 MLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEA 840 MLP+D+ YVR+A+G+MVPFSAF++S W YGSPRLERYNGLPSMEI G+AAPG S+G+A Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 841 MELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFS 900 M LME LASKLP G+GYDWTGMSYQERLSGNQAP+L AIS +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 901 VMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGL 960 VMLVVPLG++G LLAAT NDVYF VGLLTTIGLSAKNAILIVEFAKDLM+KEGKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 961 IEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIF 1020 +EATL AVRMRLRPILMTSLAFILGV+PL IS GAGSGAQNAVG GVMGGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1021 FVPVFFVVVRRRF 1033 FVPVFFVV+RR F Sbjct: 1020 FVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 6e-07 Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 23/212 (10%) Query: 100 TYQATYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTA 159 + Y A +L + + Q+ Q +++ ++ L +Q + Sbjct: 256 EQENKYVEAVNELR--VYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGL 313 Query: 160 AKAAVETARINLAYTKVTSPISGRIGKSNV-TEGALVQNGQATALATVQQLDPIYVDVTQ 218 + + + +P+S ++ + V TEG +V + T + V + D + V Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALV 372 Query: 219 SSNDFLRLKQELA----------NGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVD 268 + D + KV I D I+ + G + ++++ Sbjct: 373 QNKDIGFINVGQNAIIKVEAFPYTRYGYLV---GKVKNINLDAIEDQRLGLVFNVIISIE 429 Query: 269 QTTGSITLRAIFPNPDHTLLPGMFVRARLEEG 300 + S + I L GM V A ++ G Sbjct: 430 ENCLSTGNKNIP------LSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 8e-04 Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 49 PLQITTELPGR-TSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQATYDS 107 ++I G+ T + R E++P + I+ + KEG + G L ++ +A Sbjct: 79 QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA---- 134 Query: 108 AKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAAKAAVETA 167 D K Q++ A+L RYQ L E ++ Sbjct: 135 ---DTLKTQSSLLQARLEQTRYQILS-----RSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 168 RINLA 172 +L Sbjct: 187 LTSLI 191
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 222 bits (567), Expect = 5e-76 Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE 215
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.017 Identities = 19/125 (15%), Positives = 40/125 (32%), Gaps = 6/125 (4%) Query: 28 QNTAFARASSNGDLPTKADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRIKEE 87 N RA L + + L L+ + A L++ ++ E Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSR--LDDFSSLLHKQAIAKHAVLEQENKYVEA 264 Query: 88 TVQLRQKVAEAPEKMRQATAALTALSDVDND--EETRKIL--STLSLRQLETRVAQALDD 143 +LR ++ + + +A V E L +T ++ L +A+ + Sbjct: 265 VNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEER 324 Query: 144 LQNAQ 148 Q + Sbjct: 325 QQASV 329
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 4e-05 Identities = 40/251 (15%), Positives = 77/251 (30%), Gaps = 31/251 (12%) Query: 404 PLPETTSQVLAARQQLQRVQGATKAKKSEPAA----ATRARPVNNAALERLASVTDRVQA 459 P E +Q + + + P+ AR + A + A T Sbjct: 983 PEVEKRNQTVDTTN----ITTPNNIQADVPSVPSNNEEIARV-DEAPVPPPAPATPSETT 1037 Query: 460 RPVPSALEKAPAKKEAYRWKATTPVMQQKE--------VVATPKALKKA---LEHEKTPE 508 V ++ E AT Q +E V A + + A E ++T Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 509 LAAKLAA---------EAIERDPWAAQVSQLSLPKLVEQVALNAWKE-ESDNAVCLHLRS 558 K A E+ +V+ PK + + E +N ++++ Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 559 SQRHLNNRGAQQKLAEALS-MLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARES 617 Q N ++ A+ S ++ E T V N V P A + + + Sbjct: 1158 PQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSN 1217 Query: 618 IIADNNIQTLR 628 + + +++R Sbjct: 1218 KPKNRHRRSVR 1228
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 27.8 bits (62), Expect = 0.047 Identities = 11/43 (25%), Positives = 18/43 (41%) Query: 38 GQLAAVAIVTCDGNVYSAGDSDYRFALESISKVCTLALALEDV 80 G++ + + G +A +D RF + S KV L V Sbjct: 38 GRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARV 80
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 77.8 bits (191), Expect = 5e-19 Identities = 49/212 (23%), Positives = 81/212 (38%), Gaps = 7/212 (3%) Query: 16 KSVLITGCSSGIGLESALELKRQGFHVLAGCRKPDDVERMNS----MGFT--GVLIDLDS 69 K ITG + GIG A L QG H+ A P+ +E++ S D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PESVDRAADEVIALTDNCLYGIFNNAGFGMYGPLSTISRAQMEQQFSANFFGAHQLTMRL 129 ++D + + + N AG G + ++S + E FS N G + + Sbjct: 69 SAAIDEITARIEREMGP-IDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 130 LPAMLPHGEGRIVMTSSVMGLISTPGRGAYAASKYALEAWSDALRMELRHSGIKVSLIEP 189 M+ G IV S + AYA+SK A ++ L +EL I+ +++ P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 190 GPIRTRFTDNVNQTQSDKPVENPGIAARFTLG 221 G T ++ ++ G F G Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTG 219
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.014 Identities = 12/20 (60%), Positives = 13/20 (65%) Query: 41 LVGESGSGKSTLLAILAGLD 60 L G G GKSTL+ L GLD Sbjct: 601 LEGTGGIGKSTLINTLVGLD 620
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 55.1 bits (133), Expect = 3e-10 Identities = 39/163 (23%), Positives = 59/163 (36%), Gaps = 32/163 (19%) Query: 4 DLIIKNGTVILENEARVVDIAVKGGKIAAIG-------QD-----LGDAKEVMDASGLVV 51 D +I N ++ DI +K G+IAAIG Q +G EV+ G +V Sbjct: 69 DTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIV 128 Query: 52 SPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDRAS------- 104 + G +D+H H P + A G+T M+ PA A+ Sbjct: 129 TAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTG--PAHGTLATTCTPGPW 177 Query: 105 -IELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFK 146 I +AA ++ A G + L E+ G K Sbjct: 178 HIARMIEAADA-FPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 384 bits (988), Expect = e-137 Identities = 125/310 (40%), Positives = 175/310 (56%), Gaps = 16/310 (5%) Query: 2 KTLVVALGGNALLQRGEALTAENQYRNIASAVPALARL-ARSYRLAIVHGNGPQVGLLAL 60 K +V+ALGGNAL QRG+ + E N+ +A + AR Y + I HGNGPQVG L L Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSLLL 62 Query: 61 QNLAWKE---VEPYPLDVLVAESQGMIGYMLAQSLSAQPQM----PPVTTVLTRIEVSPD 113 A + + P+DV A SQG IGYM+ Q+L + + V T++T+ V + Sbjct: 63 HMDAGQATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQTIVDKN 122 Query: 114 DPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRD-GKYLRRVVASPQPRKILDSEAIELL 172 DPAF P K +GP Y E + L GW +K D G+ RRVV SP P+ +++E I+ L Sbjct: 123 DPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKL 182 Query: 173 LKEGHVVICSGGGGVPVTDDG---AGSEAVIDKDLAAALLAEQINADGLVILTDADAVYE 229 ++ G +VI SGGGGVPV + G EAVIDKDLA LAE++NAD +ILTD + Sbjct: 183 VERGVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAAL 242 Query: 230 NWGTPQQRAIRHATPDELAPFAKAD----GSMGPNVTAVSGYVRSRGKPAWIGALSRIEE 285 +GT +++ +R +EL + + GSMGP V A ++ G+ A I L + E Sbjct: 243 YYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEKAVE 302 Query: 286 TLAGEAGTCI 295 L G+ GT + Sbjct: 303 ALEGKTGTQV 312
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.029 Identities = 16/150 (10%), Positives = 44/150 (29%), Gaps = 8/150 (5%) Query: 299 RSQLNYSEENLKQARAALERLYTALRGTDKTVAPAGGEAFEARFIEAMDDDFNTP----- 353 + ++ +L QAR R R + P E F +++ Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 354 EAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLGLLEQEPEAFLQSGAQADDSEV 413 E +S + + + A + + + + + + + + F + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSS---LLHKQAI 249 Query: 414 AEIEALIQQRLDARKAKDWAAADAARDRLN 443 A+ L Q+ + + +++ Sbjct: 250 AKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 818 bits (2115), Expect = 0.0 Identities = 402/855 (47%), Positives = 570/855 (66%), Gaps = 20/855 (2%) Query: 20 ICYSSLAILPSFLSYAESYFNPAFLLENGTSVADLSRFERGNHQPAGVYRVDLWRNDEFI 79 + A + LS AE YFNP FL ++ +VADLSRFE G P G YRVD++ N+ ++ Sbjct: 31 FVACAFA-AQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 80 GSQDIVFESTTENTGDKSGGLMPCFNQVLLERIGLNSSAFPELAQQQNNKCINLLKAVPD 139 ++D+ F NTGD G++PC + L +GLN+++ + ++ C+ L + D Sbjct: 90 ATRDVTF-----NTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 140 ATINFDFAAMRLNITIPQIALLSSAHGYIPPEEWDEGIPALLLNYNFTGN----RGNGND 195 AT D RLN+TIPQ + + A GYIPPE WD GI A LLNYNF+GN R GN Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 196 SYFFSEL-SGINIGPWRLRNNGSWNYFRGNG--YHSEQWNNIGTWVQRAIIPLKSELVMG 252 Y + L SG+NIG WRLR+N +W+Y + +W +I TW++R IIPL+S L +G Sbjct: 205 HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLG 264 Query: 253 DGNTGSDIFDGVGFRGVRLYSSDNMYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSY 312 DG T DIFDG+ FRG +L S DNM PDSQ+GFAP + GIAR AQ+TI+QNG+ IY S Sbjct: 265 DGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNST 324 Query: 313 VSPGAFEITDLHPTSSNGDLDVTIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFR 372 V PG F I D++ ++GDL VTI E DG+ Q +T+PYS+VP+LQREG ++ +TAG++R Sbjct: 325 VPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYR 384 Query: 373 SGNSQQSSPFFFQGTALGGLPQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHA 432 SGN+QQ P FFQ T L GLP +T YGGTQL+ Y AF G+G+N+G GA+S+D+T A Sbjct: 385 SGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQA 444 Query: 433 RSQLADASRHEGDSIRFLYAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGY-EYD 491 S L D S+H+G S+RFLY KS+N GTN QL+GYRYST G++ D Y RM GY Sbjct: 445 NSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIET 504 Query: 492 YDGEHRDEPIIVNYHNLRFSRKDRLQLNVSQSLNDFGSLYISGTHQKYWNTSDSDTWYQV 551 DG + +P +Y+NL ++++ +LQL V+Q L +LY+SG+HQ YW TS+ D +Q Sbjct: 505 QDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQA 564 Query: 552 GYTSSWVGISYSLSFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFN 611 G +++ I+++LS+S ++ ++++ LNV++PF+ R ++ A AS++ Sbjct: 565 GLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWL--RSDSKSQWRHASASYS 622 Query: 612 ANRNSNGQNSWLAGVGGTLLEGHNLSYHVSQG----DTSNNGYTGSATANWQAAYGTLGG 667 + + NG+ + LAGV GTLLE +NLSY V G N+G TG AT N++ YG Sbjct: 623 MSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANI 682 Query: 668 GYNYDRDQHDVNWQLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWR 727 GY++ D + + +SGGV+ H NG+TL QPL DT VL+KAPGA ++ENQTG+ TDWR Sbjct: 683 GYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWR 742 Query: 728 GYAVMLYATVYRYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITV 787 GYAV+ YAT YR NR+ALDTNT+ +++D++ +++VVPT+GA+VRA F R+G++ L+T+ Sbjct: 743 GYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL 802 Query: 788 TQGGKPVPFGSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLP 847 T KP+PFG++V S+ + +V D+GQVYLSG PL+G++ V+WG+ N+ C+A+Y LP Sbjct: 803 THNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCVANYQLP 862 Query: 848 KQSLQQAVTVISAVC 862 +S QQ +T +SA C Sbjct: 863 PESQQQLLTQLSAEC 877
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.6 bits (147), Expect = 4e-13 Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 2/122 (1%) Query: 1 MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDYLRTRPVDLIIMDIDLP 60 M ++++ D IR + L + V T + ++ DL++ D+ +P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGY--DVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANGFVSKCNDQNDIFHAVQMI 120 + F L RIK+ + + VL +S+++ A +A + GA ++ K D ++ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LS 122 L+ Sbjct: 119 LA 120
>SALVRPPROT#Salmonella virulence-associated 28kDa protein signature. Length = 241 Score = 26.6 bits (58), Expect = 0.013 Identities = 12/34 (35%), Positives = 20/34 (58%) Query: 51 ERNEKYMASFDEMVPEFIEKMDEALAEIGFVFGE 84 + N +Y ASF +FIE ++ L+E G + G+ Sbjct: 163 QENSQYSASFLHKTRQFIECLESRLSENGVISGQ 196
>PF06291#Lambda prophage Bor protein Length = 102 Score = 164 bits (417), Expect = 7e-57 Identities = 89/97 (91%), Positives = 92/97 (94%) Query: 1 MKKMLLATALALLITGCAQQTFTVQNKQTAVAPKETITHHFFVSGIGQKKTVDAAKICGG 60 MKKML + ALA+LITGCAQQTFTV NK TAV PKETITHHFFVSGIGQKKTVDAAKICGG Sbjct: 6 MKKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKETITHHFFVSGIGQKKTVDAAKICGG 65 Query: 61 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSK 97 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCS+ Sbjct: 66 AENVVKTETQQTFVNGLLGFITLGIYTPLEARVYCSQ 102
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 81/393 (20%), Positives = 144/393 (36%), Gaps = 38/393 (9%) Query: 27 FISIVSLGLLGVAVPVQIQMMTHSTWQV---GLSVTLTGGAMFVGLMVGGVLADRYERKK 83 + V +GL+ +P ++ + HS G+ + L F V G L+DR+ R+ Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 84 VILLARGTCGIGFIGLCLNALL--PEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGR 141 V+L + G ++ + P L +Y+ + G + G A A + Sbjct: 75 VLL-------VSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVA-GAYIADITDG 126 Query: 142 ENLMQAGAITMLTVRLGSVISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPP 201 + + G V P++GGL+ GG + + AA L L LP Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM---GGFSPHAPFFAAAALNGLNFLTGCFLLPE 183 Query: 202 PPQPREHPLK----SLLAGFRFLLASPLVGGIALLGGLLTMAS----AVRVLYPALADNW 253 + PL+ + LA FR+ +V + + ++ + A+ V++ D + Sbjct: 184 SHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG--EDRF 241 Query: 254 QMSAAQIGFLYAAIP-LGAAIGALTSGKLAHSARPGLLMLLSTLGS---FLAIGLFGLMP 309 A IG AA L + A+ +G +A ++L + ++ + Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 310 MWILGVVCLALFGWLSAVSSLLQYTMLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGG 369 M +V LA G ML Q E G++ G A +G L Sbjct: 302 MAFPIMVLLASGGIGMPALQ----AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTA 357 Query: 370 LGAMMTPVASASASGFGLLIIGVLLLLVLVELR 402 + A + + +G+ + L LL L LR Sbjct: 358 IYA----ASITTWNGWAWIAGAALYLLCLPALR 386
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 62.7 bits (152), Expect = 2e-13 Identities = 60/280 (21%), Positives = 100/280 (35%), Gaps = 35/280 (12%) Query: 40 HTLESQPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQ 99 H P RIV+ LLA+ VAD + R W E L Sbjct: 29 HAAAIDPNRIVALEWLPVELLLALGIVPYG---------VADTINY-RLW---VSEPPLP 75 Query: 100 RLYIG-----EPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKS--- 151 I EP+ E + P ++ SA G S + L+ IAP N+ D Sbjct: 76 DSVIDVGLRTEPNLELLTEMKPSFMVWSAGYGPS----PEMLARIAPGRGFNFSDGKQPL 131 Query: 152 --WQSLLTQLGEITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLW 209 + LT++ ++ + A +AQ++ + + K + + ++ Sbjct: 132 AMARKSLTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVF 191 Query: 210 TPESAQGQMLEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGESLFLFAGDQ 269 P S ++L++ G NA Q + + + LAA + + L + Sbjct: 192 GPNSLFQEILDEYGIP--------NAWQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNS 243 Query: 270 KDADAIYANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQ 309 KD DA+ A PL +P V+ + + F SAM Sbjct: 244 KDMDALMATPLWQAMPFVRAGRFQRVPAVWFYGATLSAMH 283
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 444 bits (1142), Expect = e-161 Identities = 146/299 (48%), Positives = 195/299 (65%), Gaps = 18/299 (6%) Query: 1 MAIPKLQAYALPESHDIPQNKVDWAFEPQRAALLIHDMQDYFVSFWGENCPMMEQVIANI 60 MAIP +Q Y +P + D+PQNKV W +P RA LLIHDMQ+YFV + + ++ ANI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRSPEQQKVVDRLTPDADDTV 120 L++ C Q IPV YTAQP Q+ +DRALL D WGPGL P ++K++ L P+ DD V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTTATDAFMRDIKPFMVADALAD 180 L KWRYSAF R+ L +M+++ GR+QLIITG+YAHIGC+ TA +AFM DIK F V DA+AD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSRDEHLMSLKYVAGRSGRVVMTEELL------PAPIPASKA-----------ALREVIL 223 FS ++H M+L+Y AGR VMT+ LL PA + + A +R+ I Sbjct: 181 FSLEKHQMALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCENIRKQIA 240 Query: 224 PLLDESDEPFDDD-NLIDYGLDSVRMMALAARWRKVHGDIDFVMLAKNPTIDAWWKLLS 281 LL E+ E D +L+D GLDSVR+M L +WR+ ++ FV LA+ PTI+ W KLL+ Sbjct: 241 ELLQETPEDITDQEDLLDRGLDSVRIMTLVEQWRREGAEVTFVELAERPTIEEWQKLLT 299
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 364 bits (935), Expect = e-131 Identities = 110/258 (42%), Positives = 149/258 (57%), Gaps = 20/258 (7%) Query: 5 GKNVWVTGAGKGIGYATALAFVEAGAKVTGFD---------------QAFTQEQYPFATE 49 GK ++TGA +GIG A A GA + D +A E +P Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP---- 63 Query: 50 VMDVADAAQVAQVCQRLLAETERLDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFN 109 DV D+A + ++ R+ E +D LVN AG+LR G LS E+W+ TF+VN G FN Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 110 LFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRC 169 + +R G+IVTV S+ A PR M+AY +SKAA +GLELA +RC Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 170 NVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDL 229 N+VSPGST+TDMQ +LW ++ EQ I+G E FK GIPL K+A+P +IA+ +LFL S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 230 ASHITLQDIVVDGGSTLG 247 A HIT+ ++ VDGG+TLG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>BCTLIPOCALIN#Bacterial lipocalin signature. Length = 171 Score = 28.8 bits (64), Expect = 0.013 Identities = 18/98 (18%), Positives = 39/98 (39%), Gaps = 13/98 (13%) Query: 30 QGITIIKTFDAPGGMKGYLGKYQDMGVTIYLTPDGKHAISG--YMYNEKGENLSNTLIEK 87 + + + F+ YLGK+ ++ + G ++ + N+ G ++ N Sbjct: 21 ESVKPVSDFEL----NNYLGKWYEVARLDHSFERGLSQVTAEYRVRNDGGISVLN----- 71 Query: 88 EIYAPAGREMWQRMEQSHWLLDGKKDAPVIVYVFADPF 125 Y+ + W+ E + ++G D + V F PF Sbjct: 72 RGYSEE-KGEWKEAEGKAYFVNGSTDGYLKVSFFG-PF 107
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 97.1 bits (242), Expect = 4e-24 Identities = 78/342 (22%), Positives = 131/342 (38%), Gaps = 32/342 (9%) Query: 8 IGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIISMDENNH------ILVGKPAVSRR 61 + IDLGT N+LI V K L PS++++ ++ VG A Sbjct: 13 LSIDLGTANTLIYV-KGQGIVLN--------EPSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 62 TSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSLKEDAEEFLQRPIKDVVISV 121 P AA+ R M +D F ++ ++ + ++ RP V++ V Sbjct: 64 GRTPGNIAAI--RPMKDGVI----ADFFVTEKMLQHFIKQVHSNS---FMRPSPRVLVCV 114 Query: 122 PAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGLHTQQNTRSLVFDLGGGTFDVT 181 P + +R+ R +A+ AG V LI EP AAA+ GL + T S+V D+GGGT +V Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA 174 Query: 182 VLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRADVARTTLNESELAALYACVEAAK 241 V+ V + +GG+ F +++ V + + Sbjct: 175 VISLNGVVY-----SSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGD 229 Query: 242 CSNQSPLHIRWQYQEETRECEFYENELEDLWLPLLNRLRVPIEQALRDA--RLKPSQID- 298 + + R + R NE+ + L + + AL L + Sbjct: 230 EVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISER 289 Query: 299 SLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIVALGAAI 340 +VL GG + + + R+ + G + DP T VA G Sbjct: 290 GMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGK 331
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 7e-24 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 1/125 (0%) Query: 2 TNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATRKPDLIILDLGLPDGDGI 61 +L+ +D+ AIR L AL G V A DL++ D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EFIRDLRQWSA-VPVIVLSARSEESDKIAALDAGADDYLSKPFGIGELQARLRVALRRHS 120 + + +++ +PV+V+SA++ I A + GA DYL KPF + EL + AL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 ATTAP 125 + Sbjct: 124 RRPSK 128
>PF06580#Sensor histidine kinase Length = 349 Score = 31.8 bits (72), Expect = 0.012 Identities = 10/48 (20%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 785 LLENAVKYAGAQAE----IGIDAHVEGENLQLDVWDNGPGLPPGQEQT 828 L+EN +K+ AQ I + + + L+V + G +++ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKES 310
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 602 bits (1553), Expect = 0.0 Identities = 235/861 (27%), Positives = 379/861 (44%), Gaps = 63/861 (7%) Query: 5 RLSFVSCLVMAMPCAMA-VEFNLNVLDKSMRDRIDISLLKEKGVIAPGEYFVSVAVNNNK 63 RL P + A + FN L + D+S + + PG Y V + +NN Sbjct: 29 RLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGY 88 Query: 64 ISNGQ-KINWQKKGDKTIPCINDSLVDKFGLKPDIRQSLPQI--DRCIDFSSR-PEMLFN 119 ++ N +PC+ + + GL + + D C+ +S + Sbjct: 89 MATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQ 148 Query: 120 FDQANQQLNISIPQAWLAWHSENWAPPSTWKEGVAGVLMDYNLFASSYRPQDGSSSTNLN 179 D Q+LN++IPQA+++ + + PP W G+ L++YN +S + + G +S Sbjct: 149 LDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAY 208 Query: 180 AYGTAGINAGAWRLRSDYQLNKTDSEDNHDQSGGI--SRTYLFRPLPQLGSKLTLGETDF 237 +G+N GAWRLR + + S+ + T+L R + L S+LTLG+ Sbjct: 209 LNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYT 268 Query: 238 SSNIFDGFSYTGAALASDDRMLPWELRGYAPQISGIAQTNATVTISQSGRVIYQKKVPPG 297 +IFDG ++ GA LASDD MLP RG+AP I GIA+ A VTI Q+G IY VPPG Sbjct: 269 QGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPG 328 Query: 298 PFIIDDLNQ-SVQGTLDVKVTEEDGRVNNFQVSAASTPFLTRQGQVRYKLAAGQPRPSMS 356 PF I+D+ G L V + E DG F V +S P L R+G RY + AG+ R + Sbjct: 329 PFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSG-N 387 Query: 357 HQTENETFFSNEVSWGMLSNTSLYGGLLISDDDYHSAAMGIGQNMLWLGALSFDVTWASS 416 Q E FF + + G+ + ++YGG ++ D Y + GIG+NM LGALS D+T A+S Sbjct: 388 AQQEKPRFFQSTLLHGLPAGWTIYGGTQLA-DRYRAFNFGIGKNMGALGALSVDMTQANS 446 Query: 417 HFDTQQDERGLSYRFNYSKQVDATNSTISLAAYRFSDRHFHSYANYLDHKYND------- 469 G S RF Y+K ++ + + I L YR+S + ++A+ + N Sbjct: 447 TLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQD 506 Query: 470 -------------SDAQDEKQTISLSVGQPITPLNLNLYANLLHQTWWNADASTTANITA 516 + A +++ + L+V Q + LY + HQT+W A Sbjct: 507 GVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL-GRTSTLYLSGSHQTYWGTSNVDE-QFQA 564 Query: 517 GFNVDIGDWRDISISTSFNTTHYE-DKDRDNQIYLSISLPFGNGGR-----------VGY 564 G N + DI+ + S++ T K RD + L++++PF + R Y Sbjct: 565 GLNT---AFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASY 621 Query: 565 DMQNSSHS-TIHRMSWNDTLDERN--SWGMSAGL-QSDRPDNGAQVSGNYQHLSSAGEWD 620 M + + + TL E N S+ + G ++G+ + G + Sbjct: 622 SMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNAN 681 Query: 621 ISGTYAASDYSSVSSSWSGSFTATQYGAAFHRRSSTNEPRLMVSTDGVADIPVQGNLDY- 679 I ++ + D + SG A G + N+ ++V G D V+ Sbjct: 682 IGYSH-SDDIKQLYYGVSGGVLAHANGVTLGQP--LNDTVVLVKAPGAKDAKVENQTGVR 738 Query: 680 TNHFGIAVVPLISSYQPSTVAVNMNDLPDGVTVAENVIKETWIEGAIGYKSLASRSGKDV 739 T+ G AV+P + Y+ + VA++ N L D V + V GAI +R G + Sbjct: 739 TDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL 798 Query: 740 NVIIRNASGQFPPLGADIRQDDSGISVGMVGEEGHAWLSGVAENQLFTVVWGE---QSCI 796 + + + + P GA + +S S G+V + G +LSG+ V WGE C+ Sbjct: 799 LMTLT-HNNKPLPFGAMV-TSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 797 IH--LPERLEDTT-KRLILPC 814 + LP + +L C Sbjct: 857 ANYQLPPESQQQLLTQLSAEC 877
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 34.6 bits (79), Expect = 9e-05 Identities = 39/179 (21%), Positives = 78/179 (43%), Gaps = 26/179 (14%) Query: 14 SLLFTAPVYAADEGSGEIHFKGEVIEAPCEIHPEDID-KNIDLGQVTTTHINREHHSNKV 72 ++L + V+AAD + FKG++I C + +++ +I++ + + N++ + Sbjct: 15 AVLMSQHVHAADN----LTFKGKLIIPACTVQNAEVNWGDIEIQNLVQSGGNQKDFT--- 67 Query: 73 AVDIRLINCDLPASDNGSGMPVSKVGVTFDSTAKTTGATPLLSNTSAGEATGVGVRLMDK 132 ++ + P S + + VT S TG + L+ NTS G+ + L + Sbjct: 68 ------VDMNCPYS-------LGTMKVTITSNG-QTGNSILVPNTSTASGDGLLIYLYNS 113 Query: 133 NDGNI----VLGSAAPDLDLDASSSEQTLNFFAWMEQIDNAVDVTAGEVTANATYVLDY 187 N+ I LGS + ++ + + +A + N + AG +A AT V Y Sbjct: 114 NNSGIGNAVTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQSLQAGTFSATATLVASY 172
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 30.6 bits (69), Expect = 0.006 Identities = 11/41 (26%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 14 VDDAPRMQDYTLEADEGRDM-MLLDALIQLKEKDPSLSFRR 53 +++ + T+E + + MLLDAL+++ + DP L + Sbjct: 339 IENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYV 379
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 27/196 (13%), Positives = 56/196 (28%), Gaps = 12/196 (6%) Query: 48 EVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSE-EKASTPAQRQQASL 106 E+ + I+ ++ EG +V +L +L + +S +A R Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 107 EEQNNDAL----SPAIRRLLAEHNLDASAIKGTGVGGRLTRED----VEKHLAKAPAKES 158 + L P + + T ++ E +L K A+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 159 APAAAAPAAQPALAARSEKRVPMTRLRKRVA---ERLLEAKNSTAMLTTFNEVNMKPIMD 215 A + + + L + A +LE +N V + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 216 LRKQYGEAFEKRHGIR 231 + + A E+ + Sbjct: 278 IESEILSAKEEYQLVT 293
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 60.1 bits (145), Expect = 9e-12 Identities = 34/199 (17%), Positives = 69/199 (34%), Gaps = 8/199 (4%) Query: 99 EQERLKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEE 158 E E+ Q QA+ + E A A ++ E Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVP----SNNEEIARVDEAPVPPPAPATPSETTET 1039 Query: 159 AAK--KAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAA--AAEARKKAATE 214 A+ K + +K E +A + A+ ++ A+ A + +K + E A +E ++ TE Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 215 AAEKAKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKK 274 E A E E+KA E + + K+ + +A ++ + + Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 275 AAAAKAAAEKAAAAKAAAE 293 + A + A + ++ Sbjct: 1160 SQTNTTADTEQPAKETSSN 1178 Score = 57.0 bits (137), Expect = 9e-11 Identities = 30/236 (12%), Positives = 85/236 (36%), Gaps = 11/236 (4%) Query: 68 QSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAKQA 127 Q+ S ++E+ ++ +E ++ + +K E+ A + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKN--EQDATET 1061 Query: 128 ELKQKQ-AEEAAAKAAAD------AKAKAEADAKAAEEAAKKAAADAKKKAEAEAAKAAA 180 + ++ A+EA + A+ A++ +E E + A + ++KA+ E K Sbjct: 1062 TAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQE 1121 Query: 181 EAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAA 240 + ++ + ++++E + A AR+ T ++ +++ A E+ A + + Sbjct: 1122 VPKVTSQVSPK--QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNV 1179 Query: 241 EKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAAAEADD 296 E+ + + + A ++ K + ++ + Sbjct: 1180 EQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Score = 56.2 bits (135), Expect = 2e-10 Identities = 28/228 (12%), Positives = 75/228 (32%), Gaps = 2/228 (0%) Query: 66 RMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQERLKQLEKERLAAQEQKKQAEEAAK 125 R ++E+ + + + Q+ E +E Q E + +EKE A E +K E Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 126 QAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAK--KAAADAKKKAEAEAAKAAAEAQ 183 +++ KQ + + A+ + + E ++ A + E + + Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 184 KKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAEAEKKAAAEKAAADKKAAAEKA 243 ++ + E A + + + K + ++ ++ +++ Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245 Query: 244 AADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAAEKAAAAKAA 291 +D +A A+ A + A ++ ++ + Sbjct: 1246 TVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQ 1293 Score = 55.5 bits (133), Expect = 2e-10 Identities = 32/265 (12%), Positives = 86/265 (32%), Gaps = 14/265 (5%) Query: 51 DAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAE-ELREKQAAEQER------L 103 D V A + ++ ++K+ + + EQ A E + ++ A++ + Sbjct: 1021 DEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANT 1080 Query: 104 KQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAAKKA 163 + E + ++ ++ Q K+ +K+ KA + + E ++ + K+ Sbjct: 1081 QTNEVAQSGSETKETQ-TTETKETATVEKE-----EKAKVETEKTQEVPKVTSQVSPKQE 1134 Query: 164 AADA-KKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEKAKAE 222 ++ + +AE K+ ++ + A+ ++ + Sbjct: 1135 QSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNS 1194 Query: 223 AEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAAAAKAAA 282 + A + +++ K + + + + A + A + Sbjct: 1195 VVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTS 1254 Query: 283 EKAAAAKAAAEADDIFGELSSGKNA 307 A + A A F L+ GK Sbjct: 1255 TNTNAVLSDARAKAQFVALNVGKAV 1279
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 40.0 bits (93), Expect = 3e-06 Identities = 30/159 (18%), Positives = 53/159 (33%), Gaps = 20/159 (12%) Query: 7 RLDKNDAAVLLVDHQAGLLSLVRDIEP--DKFKNNVLALGDLAKYFNLPTILTT---SFE 61 D N A +L+ D Q + + N+ L + +P + T S Sbjct: 25 VPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQN 84 Query: 62 TGPNGPLV----PELKAQFPDTPYIAR----PGNI-------NAWDNEDFVKAVKATGKK 106 L P L + + I ++ +A+ + ++ ++ G+ Sbjct: 85 PDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRD 144 Query: 107 QLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNE 145 QLII G+ + A A E F V DA F+ Sbjct: 145 QLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.5 bits (63), Expect = 0.012 Identities = 26/92 (28%), Positives = 37/92 (40%), Gaps = 14/92 (15%) Query: 6 LTAFITVVCATSSVMAADDNAITDGSVTFNGKVIAPACTLVAATKDSVVTLPDVSATKLQ 65 L + V + V AAD+ +TF GK+I PACT+ A V D+ L Sbjct: 9 LPVMLGAVLMSQHVHAADN-------LTFKGKLIIPACTVQNAE----VNWGDIEIQNLV 57 Query: 66 TNGQVS---GVQIDVPIELKDCDTTVTKNATF 94 +G V ++ P L T+T N Sbjct: 58 QSGGNQKDFTVDMNCPYSLGTMKVTITSNGQT 89
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 827 bits (2139), Expect = 0.0 Identities = 414/862 (48%), Positives = 569/862 (66%), Gaps = 18/862 (2%) Query: 15 GVPSFIGGLVVFVSAAFNAQAETWFDPAFFKDDPSMVADLSRFEKGQKITPGVYRVDIVL 74 G + F + A + AE +F+P F DDP VADLSRFE GQ++ PG YRVDI L Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYL 84 Query: 75 NQTIVDTRNVNFVEITPEKGIAACLTTESLDAMGVNTDAFPAFKQLDKQACVPLAEIIPD 134 N + TR+V F E+GI CLT L +MG+NT + L ACVPL +I D Sbjct: 85 NNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHD 144 Query: 135 ASVTFNVNKLRLEISVPQIAIKSNARGYVPPERWDEGINALLLGYSFSGANSIHSSADSD 194 A+ +V + RL +++PQ + + ARGY+PPE WD GINA LL Y+FSG + + + Sbjct: 145 ATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNS 204 Query: 195 SGDSYFLNLNSGVNLGPWRLRNNSTWSR-----SSGQTAEWKNLSSYLQRAVIPLKGELT 249 +LNL SG+N+G WRLR+N+TWS SSG +W++++++L+R +IPL+ LT Sbjct: 205 --HYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLT 262 Query: 250 VGDDYTAGDFFDSVSFRGVQLASDDNMLPDSLKGFAPVVRGIAKSNAQITIKQNGYTIYQ 309 +GD YT GD FD ++FRG QLASDDNMLPDS +GFAPV+ GIA+ AQ+TIKQNGY IY Sbjct: 263 LGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYN 322 Query: 310 TYVSPGAFEISDLYSTSSSGDLLVEIKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAK 369 + V PG F I+D+Y+ +SGDL V IKEADGS ++VP+SSVPLLQR+G +Y++T + Sbjct: 323 STVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGE 382 Query: 370 YRTNSNEQQESKFAQATLQWGGPWGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDAT 429 YR+ + +Q++ +F Q+TL G P G T YGG Q A+ YRA FG+G N+G GA+S D T Sbjct: 383 YRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMT 442 Query: 430 QAKSTLADQSEHKGQSYRFLYAKTLNHLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGY-- 487 QA STL D S+H GQS RFLY K+LN GTN QL+GYRYSTSG++ +DT Y M+GY Sbjct: 443 QANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNI 502 Query: 488 EFNDGDDEDTPMWSRYYNLFYTKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLL 547 E DG + P ++ YYNL Y KRGKLQ+ ++QQLG + YLSGS QTYW T D Sbjct: 503 ETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQF 562 Query: 548 QFGYNTQIKDLSLGISWNYSKSRGQPDADQVFALNFSLPLNLLLPRSNDSYTRKKNYAWM 607 Q G NT +D++ +S++ +K+ Q DQ+ ALN ++P + L + S R +A Sbjct: 563 QAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWR---HASA 619 Query: 608 TSNTSIDNEGHTTQNLGLTETLLDDGNLSYSVQQGYNSEGKTANGS---ASMDYKGAFAD 664 + + S D G T G+ TLL+D NLSYSVQ GY G +GS A+++Y+G + + Sbjct: 620 SYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGN 679 Query: 665 ARVGYNYSDNGSQQQLNYALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGL 724 A +GY++SD+ +QL Y +SG ++AH+ G+TLGQ L +T VL+ APGA++ +V N TG+ Sbjct: 680 ANIGYSHSDD--IKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 725 KTDWRGYTVVPYATSYRENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGAR 784 +TDWRGY V+PYAT YRENR+ALD +L NVDL+NAV NVVPT+GA+V AEF A G + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIK 797 Query: 785 VLMKTSKQGIPLRFGAIATLDGVQANSGIIDDDGSLYMAGLPAKGTISVRWGEAPDQICH 844 +LM + PL FGA+ T + +SGI+ D+G +Y++G+P G + V+WGE + C Sbjct: 798 LLMTLTHNNKPLPFGAMVTSES-SQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 845 INYELTEQQINSAITRMDAICR 866 NY+L + +T++ A CR Sbjct: 857 ANYQLPPESQQQLLTQLSAECR 878
>CLENTEROTOXN#Clostridium enterotoxin signature. Length = 319 Score = 31.6 bits (71), Expect = 0.004 Identities = 13/48 (27%), Positives = 22/48 (45%) Query: 295 VGVVVTDSQNNIISPAGGTLPLSIPDDADSIARMNVYPVSTTGVPPET 342 + V TD + I+ A T L++ D +S N+Y ++ P T Sbjct: 188 LTVPSTDIEKEILDLAAATERLNLTDALNSNPAGNLYDWRSSNSYPWT 235
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 75.4 bits (185), Expect = 2e-18 Identities = 44/176 (25%), Positives = 71/176 (40%), Gaps = 23/176 (13%) Query: 12 TFDPQQSALIVVDMQNAYATPGGYLDLAGFDVSTTRPVIANIQTAVTAARAAGMLIIWFQ 71 DP ++ L++ DMQN + +D S + ANI+ G+ +++ Sbjct: 25 VPDPNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQLGIPVVY-- 76 Query: 72 NGWDEQYVEAGGPGSPNFHKSNALKTMRKQPQLQGKLLAKGSWDYQLVDELVPQPGDIVL 131 PGS N L G L G ++ +++ EL P+ D+VL Sbjct: 77 ---------TAQPGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELAPEDDDLVL 121 Query: 132 PKPRYSGFFNTPLDSILRSRGIRHLVFTGIATNVCVESTLRDGFFLEYFGVVLEDA 187 K RYS F T L ++R G L+ TGI ++ T + F + + DA Sbjct: 122 TKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDA 177
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 2e-15 Identities = 30/165 (18%), Positives = 62/165 (37%), Gaps = 8/165 (4%) Query: 10 GKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQIAELAGVSKTNLLYYFPSKEALYIAV 69 K + ++ IL AL FSQ G T L +IA+ AGV++ + ++F K L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 70 LRQILDIWLAPLKAFREDF--APLAAIKEYIRLKLEVSRDYPQASRLFCM-----EMLAG 122 ++ F PL+ ++E + LE + + L + E + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 123 APLLMDELTGDLKALIDEKSALIAGWVKSGKL-APIDPQHLIFMI 166 ++ D + +++ L A + + ++ Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 29.8 bits (67), Expect = 0.047 Identities = 27/183 (14%), Positives = 61/183 (33%), Gaps = 23/183 (12%) Query: 450 WPRAAENELKK-AEVIEPRNINLEVEQAWTALTLQEWQQA--AVLTHDVVEREPQDPGVV 506 + A E + A +++ + +E + + L ++ ++E E + + Sbjct: 47 YLEVARQEHEVFASILKNNLVEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTI 106 Query: 507 -RLK---RAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYS---PPLKDNWRGFA 559 LK ++ + N+ I+G E + DL P+ + F Sbjct: 107 NLLKDYFSSLTIDNMISKMISGVVT--EELKNYTSSLDDLVNGANLFIIDPMPNVL--FT 162 Query: 560 GFGYADGQFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDN 619 D S G G+ + + + R E +AE +F + + W + + Sbjct: 163 ----RDPFASIGNGVT---INKMFTKVRQ--RETIFAEYIFKYHPVYKENVPIWLNRWEE 213 Query: 620 WRI 622 + Sbjct: 214 ASL 216
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 41.5 bits (97), Expect = 5e-06 Identities = 17/49 (34%), Positives = 29/49 (59%) Query: 354 TLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQILNTLVNLR 402 L+N S V+L +E N+ Q+ Y +NAQ ++T + I + L+N+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 36.9 bits (85), Expect = 1e-04 Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 6 AVSGLNAAATNLDVIGNNIANSATYGFKSGTASFAD----MFAGSKVGLGVKVAGI 57 A+SGLNAA L+ NNI++ G+ T A + AG VG GV V+G+ Sbjct: 7 AMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVSGV 62
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 43.8 bits (103), Expect = 4e-07 Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 14/81 (17%) Query: 3 SSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDLLYQTIRQPGAQSSEQTTL 62 S + A +GL+A Q ++ +NN+++ + G+ RQ + + +TL Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQIGTGVRPVATERLHSQ 83 +G +G GV +R + Sbjct: 48 GAGGWVGNGVYVSGVQREYDA 68 Score = 41.1 bits (96), Expect = 3e-06 Identities = 11/41 (26%), Positives = 21/41 (51%) Query: 220 ETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL 260 S VN+ EE N+ + Q+ Y N++ + T + + L + Sbjct: 505 SISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 349 bits (897), Expect = e-126 Identities = 232/232 (100%), Positives = 232/232 (100%) Query: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY Sbjct: 1 MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPTPVANGSIFQSAQPINY 60 Query: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA Sbjct: 61 GYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKTNFGFDTVPRYLQGLFGNA 120 Query: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF Sbjct: 121 RADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRF 180 Query: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM Sbjct: 181 SGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 427 bits (1100), Expect = e-152 Identities = 157/363 (43%), Positives = 213/363 (58%), Gaps = 9/363 (2%) Query: 4 FLSALILLLVTTAAQAERIRDLTSVQGVRQNSLIGYGLVVGLDGTGDQTTQTPFTTQTLN 63 F + L A RI+D+ S+Q R N LIGYGLVVGL GTGD +PFT Q++ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 64 NMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQTIDVVVSSMGNAKSLRGGTLLM 123 ML LGIT G + KN+AAVMVTA+LPPF G +DV VSS+G+A SLRGG L+M Sbjct: 73 AMLQNLGITTQGGQS-NAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLIM 131 Query: 124 TPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQLNGGRITNGAVIERELPSQFGVGN 183 T L G D Q+YA+AQG ++V G A +++ R+ NGA+IERELPS+F Sbjct: 132 TSLSGADGQIYAVAQGALIVNGFSAQGDAATLTQGVTTSARVPNGAIIERELPSKFKDSV 191 Query: 184 TLNLQLNDEDFSMAQQIADTINRVR----GYGSATALDARTIQVRVPSGNSSQVRFLADI 239 L LQL + DFS A ++AD +N G A D++ I V+ P + R +A+I Sbjct: 192 NLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKPRV-ADLTRLMAEI 250 Query: 240 QNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVAQGNLSVTVNRQANVSQPDTPFGG 299 +N+ V T AKVVIN RTG++V+ +V + AV+ G L+V V V QP PF Sbjct: 251 ENLTVE-TDTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQP-APFSR 308 Query: 300 GQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRALNALGATPMDLMSILQSMQSAGCLR 359 GQT V PQT I Q G + ++ L +V LN++G +++ILQ ++SAG L+ Sbjct: 309 GQTAVQPQTDIMAMQEGSKV-AIVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGALQ 367 Query: 360 AKL 362 A+L Sbjct: 368 AEL 370
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 511 bits (1318), Expect = 0.0 Identities = 313/313 (100%), Positives = 313/313 (100%) Query: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG Sbjct: 1 MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMRDALPKDG 60 Query: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET Sbjct: 61 LFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLET 120 Query: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL Sbjct: 121 VVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAAL 180 Query: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL Sbjct: 181 ESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYL 240 Query: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK Sbjct: 241 EALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAGYATDPHYARKLTNMIQQMKSISDK 300 Query: 301 VSKTYSMNIDNLF 313 VSKTYSMNIDNLF Sbjct: 301 VSKTYSMNIDNLF 313
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 684 bits (1766), Expect = 0.0 Identities = 546/546 (100%), Positives = 546/546 (100%) Query: 2 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 61 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 121 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 181 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 241 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 242 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 301 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 302 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 361 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPAVLQNTKNKGDVAIGATVTDASAVLATD 360 Query: 362 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 421 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV Sbjct: 361 YKISFDNNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPVSDAIV 420 Query: 422 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 481 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN Sbjct: 421 NMDVLITDEAKIAMASEEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYASLVSDIGN 480 Query: 482 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 541 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD Sbjct: 481 KTATLKTSSATQGNVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFD 540 Query: 542 ALINIR 547 ALINIR Sbjct: 541 ALINIR 546
>FLAGELLIN#Flagellin signature. Length = 507 Score = 45.4 bits (107), Expect = 2e-07 Identities = 41/226 (18%), Positives = 79/226 (34%), Gaps = 9/226 (3%) Query: 7 MMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPIAASQAVVLSQAQAQNSQYTLAR 66 ++ Q N+ +S + + E++S+G R+ + DD + A + +Q + Sbjct: 11 LLTQNNLNKSQSSLSSAI---ERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQASRNA 67 Query: 67 TFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTLSDDDRASLATDIQGLRDQLLNLAN 126 E L+++ +Q +E V A+NGT SD D S+ +IQ +++ ++N Sbjct: 68 NDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEEIDRVSN 127 Query: 127 TTDGNGRYIFAGYKTETAPFSEEKGKYVGGAESIKQQVDASRSMVIGHTGDKIFDSITSN 186 T NG + + G E+I + +G G + + Sbjct: 128 QTQFNGVKVLSQDNQMKIQVGANDG------ETITIDLQKIDVKSLGLDGFNVNGPKEAT 181 Query: 187 AVAEPDGSASETNLFAMLDSAIAALKTPVADSEADKETAAAALDKT 232 + T A + + TA DK Sbjct: 182 VGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKV 227
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 66.2 bits (161), Expect = 6e-13 Identities = 47/288 (16%), Positives = 84/288 (29%), Gaps = 36/288 (12%) Query: 513 PSEEEFAERKRPEQPALATFAMPDVPPAPT-PAEPAAPVVAPAPKAAPATPAAPAQPGLL 571 P E+ + DVP P+ E A AP P APATP+ Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETT----- 1037 Query: 572 SRFFGALKALFSGGEETKPTEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRDTRSER-- 629 ET + Q QN + + + ++ Sbjct: 1038 ---------------ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 630 TEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTADEQQAPRRERSRRRNDDKRQ 689 E + + E + + ++TA + + TEK + + + + + + Q Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ 1142 Query: 690 AQ---QEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSV--AEEAVVAPV 744 A+ + +N++E Q + +P + + Q V +V V P Sbjct: 1143 AEPARENDPTVNIKEPQSQTNTTADTEQPA--KETSSNVEQPVTESTTVNTGNSVVENPE 1200 Query: 745 VEETVAAEPIVQEAPA------PRTELVKVPLPVVAQTAPEQQEENNA 786 +P V + R + VP V T A Sbjct: 1201 NTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 63.5 bits (154), Expect = 4e-12 Identities = 46/261 (17%), Positives = 82/261 (31%), Gaps = 26/261 (9%) Query: 551 VAPAPKAAPATPAAPAQPGLLSRFFGALKALFSGGEETKPTEQP-APKAEAKPERQQDRR 609 P + S E + E P P A A P Sbjct: 991 TVDTTNITTPNNIQADVPSVPSN----------NEEIARVDEAPVPPPAPATPSETT--- 1037 Query: 610 KPRQNNRRDRNERRDTRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEV------T 663 N ++++++ D E +NR A++ + + + Q EV T Sbjct: 1038 -----ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSET 1092 Query: 664 EKARTADEQQAPRRERSRRRNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQR 723 ++ +T + ++ E+ + + + Q+ K + + QE + + + R Sbjct: 1093 KETQTTETKETATVEKEEKAKVETEKTQEVPK-VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 724 QLNQKVRYEQSVAEEAVVAPVVEETVAAEPIVQEAPAPRTELVKVPLPVVAQTAPEQQEE 783 +N K Q+ P E + E V E+ T V P A Q Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 784 NNADNRDNGGMPRRSRRSPRH 804 N+ + RRS RS H Sbjct: 1212 NSESSNKPKNRHRRSVRSVPH 1232
>SECA#SecA protein signature. Length = 901 Score = 57.2 bits (138), Expect = 2e-12 Identities = 16/28 (57%), Positives = 20/28 (71%) Query: 125 IDGTRPQFGRNDPCPCGSGKKFKKCCGQ 152 + GRNDPCPCGSGKK+K+C G+ Sbjct: 872 AQTGERKVGRNDPCPCGSGKKYKQCHGR 899
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 7e-22 Identities = 40/152 (26%), Positives = 64/152 (42%), Gaps = 3/152 (1%) Query: 10 ILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDALELLGGFTPDLMICDIAMPRMNGLKL 69 IL+ +D+ R++L+ S G + ++ + DL++ D+ MP N L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 70 LEHIRNRGDQTPVLVISATENMADIAKALRLGVEDVLLKPVKDLNRLREMVFACLYPSMF 129 L I+ PVLV+SA KA G D L KP DL L ++ L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRAL--AEP 122 Query: 130 NSRVEEEERLFRDWDAMVDNPAAAAKLLQELQ 161 R + E +D +V AA ++ + L Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLA 154
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.008 Identities = 9/16 (56%), Positives = 11/16 (68%) Query: 55 VVGESGCGKSTFARAI 70 + GESG GK ARA+ Sbjct: 165 ITGESGTGKELVARAL 180
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.1 bits (127), Expect = 7e-10 Identities = 26/158 (16%), Positives = 61/158 (38%), Gaps = 13/158 (8%) Query: 120 EAMNALHAEALEMNIKFDQELAAKFEADHEMALLMNKDFDRDREEQRRLAEQARREHEER 179 A + E + N K + + K E D + R +A++A+ + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTA----------QNREVAKEAKSNVKAN 1079 Query: 180 IKREAAEQARRDAEAKHKAEIEAAARREAEEKARAELAERQ---RIEAEQRAEREKKETE 236 + Q+ + + E + A E EEKA+ E + Q ++ ++ ++E+ ET Sbjct: 1080 TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 237 ERARREKEEAVAAERRRQEEAEAARLVEEQRKAEEEAR 274 + E ++ +++ + ++ A+E + Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Score = 40.0 bits (93), Expect = 1e-05 Identities = 18/95 (18%), Positives = 37/95 (38%), Gaps = 8/95 (8%) Query: 185 AEQARRDAE-AKHKAEIEAAARREAEEKARAELAERQRIEAEQRAEREKKETEERARREK 243 +E AE +K +++ ++A E R+ + + + +T E A+ Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATE---TTAQNREVAKEAKSNVKANTQTNEVAQSGS 1090 Query: 244 EEAVAAERRRQEEAEAARLVEEQRKAEEEARRAAD 278 E +E A VE++ KA+ E + + Sbjct: 1091 ETKETQTTETKETAT----VEKEEKAKVETEKTQE 1121 Score = 38.9 bits (90), Expect = 2e-05 Identities = 23/130 (17%), Positives = 48/130 (36%), Gaps = 5/130 (3%) Query: 169 AEQARREHE-ERIKREAAEQARRDAEAKHKAEIEAAARREAEEKARAELAERQRIEAEQR 227 E+ + + I QA + + EI A A +E AE Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN- 1043 Query: 228 AEREKKETEERARREKEEAVAAERRRQEEAEAARLVEEQRKAEEEARRAADKEHRRTVNR 287 +++ +T E+ ++ E A + R+ EA V+ + E A+ ++ + +T Sbjct: 1044 -SKQESKTVEKNEQDATETTA--QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 288 RVYADLIAQG 297 + A + + Sbjct: 1101 KETATVEKEE 1110
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.2 bits (70), Expect = 4e-04 Identities = 16/57 (28%), Positives = 20/57 (35%), Gaps = 2/57 (3%) Query: 41 GPMPAVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKV 97 P+PA G GS E + EA W +P A V +V KV Sbjct: 268 APLPA--EGKFAVIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 259 bits (662), Expect = 7e-90 Identities = 239/239 (100%), Positives = 239/239 (100%) Query: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA Sbjct: 1 MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQA 60 Query: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESR 120 Query: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF Sbjct: 121 PASPFENTAPARLTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 180 Query: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ Sbjct: 181 DVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGSGIVVNILFKINGTTEIQ 239
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 341 bits (877), Expect = e-117 Identities = 125/341 (36%), Positives = 182/341 (53%), Gaps = 23/341 (6%) Query: 6 DNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKELIASRLHYLSSRWQGPFISLNC 65 L+G + + E+ ++ L D ++I GE GTGKEL+A LH R GPF+++N Sbjct: 137 MPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINM 196 Query: 66 AALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGGTLFLDELATAPMMVQEKLLRVIE 125 AA+ +L++SELFGHE GAFTGAQ R GRFE+A+GGTLFLDE+ PM Q +LLRV++ Sbjct: 197 AAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQ 256 Query: 126 YGELERVGGSQPLQVNVRLVCATNADLPAMVNEGTFRADLLDRLAFDVVQLPPLRERESD 185 GE VGG P++ +VR+V ATN DL +N+G FR DL RL ++LPPLR+R D Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAED 316 Query: 186 IMLMAEYFAIQMCREIKLPLFPGFTERARETLLNYRWPGNIRELKNVVERSVYRHGTSDY 245 I + +F Q +E F + A E + + WPGN+REL+N+V R + Sbjct: 317 IPDLVRHFVQQAEKEGLDVK--RFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVI 374 Query: 246 PLDDIIID---PFKRRPPEDAIAVSETTSLPTLPLD------------------LREFQM 284 + I + P E A A S + S+ + Sbjct: 375 TREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLA 434 Query: 285 QQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI 325 + E L+ +L + NQ +AA+LLGL + R +++ + Sbjct: 435 EMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 24.6 bits (53), Expect = 0.030 Identities = 7/43 (16%), Positives = 17/43 (39%) Query: 30 SGRSELSQSEQQRLAQLADEAKRMRERIQALESILDAEHPNWR 72 +G+ + + A A++A + + E L + +W Sbjct: 37 AGQLGIEATGSGVCAGPAEQANALAGDVACAEQWLGDKPVSWS 79
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 32.0 bits (72), Expect = 5e-04 Identities = 28/93 (30%), Positives = 46/93 (49%), Gaps = 7/93 (7%) Query: 16 LFTATLQAADVTITVNGRVVAKPCTIQT-KEANVNLGDLYTRNLQQPGSASGWHNITLSL 74 L T+ ADV I + G V PCTI + V+ G++ N + ++ G +S+ Sbjct: 11 LLTSVAVLADVQINIRGNVYIPPCTINNGQNIVVDFGNI---NPEHVDNSRGEVTKNISI 67 Query: 75 TDCPVETSAVTAIVTGSTDNTGYYKNEGTAENI 107 + CP ++ ++ VTG+T G +N A NI Sbjct: 68 S-CPYKSGSLWIKVTGNTMGVG--QNNVLATNI 97
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 53.3 bits (128), Expect = 7e-10 Identities = 41/192 (21%), Positives = 83/192 (43%), Gaps = 8/192 (4%) Query: 36 LSDIAQSFHMQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLS 95 L DIA F+ A + T + ++ + + ++ Q+ ++LL+ ++ V+ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 96 FLSWS-FTVLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGL 154 F+ S F++L+++R A F ++ + R P R +A LI + A+ +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 155 PLGRIVGQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSI 214 +G ++ Y W I + +IT+ L+KLL + LMS+ Sbjct: 157 AIGGMIAHYIHWSY-LLLIPMITIITVPFLMKLLK------KEVRIKGHFDIKGIILMSV 209 Query: 215 YLLTVVVVTAHY 226 ++ ++ T Y Sbjct: 210 GIVFFMLFTTSY 221
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 1e-06 Identities = 42/239 (17%), Positives = 82/239 (34%), Gaps = 18/239 (7%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLI---GYAMTIALTIGVVFSLGF 63 R +L++ L +G G +P + L R S D+ G + + + + Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLL-RDLVHSNDVTAHYGILLALYALMQFACAPVL 63 Query: 64 GILADKFDKKRYMLLAITAFASGFIAITLVNNVTLVVLFFALINCAYSVFATVLKAWFAD 123 G L+D+F ++ +L+++ A + + + ++ + + + A A+ AD Sbjct: 64 GALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIAD 122 Query: 124 NLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSINLPFWLAAICSAFPMLFIQIWVK 183 + + F G GP LG L+ S + PF+ AA + L + Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 184 RSEK---------IIATETGSVWSPKVLLQDKALLWFTCSGFLASFVSGAFASCISQYV 233 S K + W + A L F+ V A+ + Sbjct: 183 ESHKGERRPLRREALNPLASFRW--ARGMTVVAALMAV--FFIMQLVGQVPAALWVIFG 237 Score = 32.9 bits (75), Expect = 0.002 Identities = 22/155 (14%), Positives = 60/155 (38%), Gaps = 2/155 (1%) Query: 7 RSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDLIGYAMTIALTIGVVF-SLGFGI 65 +AL+A ++ + I+ ++ IG ++ + + ++ G Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP 269 Query: 66 LADKFDKKRYMLLAITAFASGFIAITLVNNVTLVVLFFALINCAYSVFATVLKAWFADNL 125 +A + ++R ++L + A +G+I + + L+ + L+A + + Sbjct: 270 VAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQV 328 Query: 126 SSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI 160 + ++ + ++ +GP L T + SI Sbjct: 329 DEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASI 363
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (249), Expect = 2e-27 Identities = 70/244 (28%), Positives = 114/244 (46%), Gaps = 16/244 (6%) Query: 2 IVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDELGDNLYIAQ---LDVRNR 58 I +TGA G GE + R QG + A E+L+++ L A+ DVR+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETMIDTNNKGLVYMTRAVL 118 AAI+E+ A + E IDILVN AG+ L H S E+WE N+ G+ +R+V Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 119 PGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLNLRTDLHGTAVRVTDIEPG 178 M++R G I+ +GS P Y ++KA F+ L +L +R + PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 LVGGTEFSNVRFKGDDGKAE------KTYQNTVALT----PEDVSEAV-WWVSTLPAHVN 227 T+ + ++G + +T++ + L P D+++AV + VS H+ Sbjct: 189 ST-ETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 228 INTL 231 ++ L Sbjct: 248 MHNL 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.0 bits (114), Expect = 4e-08 Identities = 33/118 (27%), Positives = 55/118 (46%), Gaps = 16/118 (13%) Query: 44 VGAFIFGKMGDRIGRKKVLFITITMMGICTTLIGVLPTYAQIGVFAPILLVTLRIIQGLG 103 +G ++GK+ D++G K++L I + + + V ++ + + A R IQG G Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMA-------RFIQGAG 116 Query: 104 AGAEISGAGTMLAEYAPKGKR----GIISSFVAMGTNCGTLSATAI-----WAFMFFI 152 A A + ++A Y PK R G+I S VAMG G I W+++ I Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLI 174
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 60.6 bits (147), Expect = 5e-17 Identities = 19/46 (41%), Positives = 32/46 (69%) Query: 4 QKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVFTAYEP 49 + +++ ++++CLT+++ +TRK LCE+R R G EVA F AYE Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 31.2 bits (71), Expect = 0.002 Identities = 14/61 (22%), Positives = 28/61 (45%), Gaps = 5/61 (8%) Query: 74 SNKAELTAIIARETGKPRWEAATEVTAMINKIAISIKAYHVRTGEQRSEMPDGAASLRHR 133 +NK +L A +A T + ++A V A+ + ++ + GE+ + G +R R Sbjct: 2 ANKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAK-----GEKVQLIGFGNFEVRER 56 Query: 134 P 134 Sbjct: 57 A 57
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 37.3 bits (86), Expect = 3e-05 Identities = 36/192 (18%), Positives = 56/192 (29%), Gaps = 58/192 (30%) Query: 2 PPRALLLV-DLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRGEAVI-----ASQD--- 52 P RA+LL+ D+QN F +L + C G V+ SQ+ Sbjct: 28 PNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPDD 87 Query: 53 -------WHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLHQKAI 105 W P + + + P D + T W Sbjct: 88 RALLTDFWGPGLNSGPYEEKIITELAPEDDDLV-LTKW---------------------- 124 Query: 106 AAVFHKGENPLVDSYSAFFDNGRRQKTSLDDWLRDHEIDELIVMGLATDYCVKFTVLDAL 165 YSAF +T+L + +R D+LI+ G+ T +A Sbjct: 125 -------------RYSAFK------RTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAF 165 Query: 166 QLGYKVNVITDG 177 K + D Sbjct: 166 MEDIKAFFVGDA 177
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.9 bits (93), Expect = 2e-05 Identities = 30/129 (23%), Positives = 50/129 (38%), Gaps = 1/129 (0%) Query: 65 ALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAATGAAFVPDMY-WLIFFRFLMGTG 123 A M + IG+ G + D G +R ++I + + LI RF+ G G Sbjct: 57 AFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG 116 Query: 124 MGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPMLSAAIGVVVIAFFSWRIMFLLGG 183 A + +IP RGK + + + AIG ++ + W + L+ Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM 176 Query: 184 IGILLAWFL 192 I I+ FL Sbjct: 177 ITIITVPFL 185
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 31.0 bits (70), Expect = 0.011 Identities = 33/142 (23%), Positives = 48/142 (33%), Gaps = 23/142 (16%) Query: 71 MFLGALVGGIIGDKTGRRNAFILYEAIHIASMVVGAFSPNMDF-LIACRFVMGVGLGALL 129 +G V G + D+ G + + I+ V+G + LI RF+ G G A Sbjct: 62 FSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP 121 Query: 130 VTLFAGFTEYMPGRNR----GTWSSRVSFIGNWSYPLCSLIAMGLTPLISA----EWNWR 181 + Y+P NR G S V+ + G+ P I +W Sbjct: 122 ALVMVVVARYIPKENRGKAFGLIGSIVA------------MGEGVGPAIGGMIAHYIHWS 169 Query: 182 VQLLIPAILSLIATALAWRYFP 203 LLIP I I T Sbjct: 170 YLLLIPMI--TIITVPFLMKLL 189
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 27.7 bits (61), Expect = 0.022 Identities = 18/61 (29%), Positives = 26/61 (42%) Query: 49 QGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRGVTLMGS 108 Q +I L IG + + LPPS ++ N ++ A VS LG +TL G Sbjct: 174 QRSAIVDGGLHIGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPAAVSVLGASELTLDGG 233 Query: 109 Q 109 Sbjct: 234 H 234
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.2 bits (68), Expect = 0.017 Identities = 10/57 (17%), Positives = 17/57 (29%), Gaps = 2/57 (3%) Query: 164 RFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRF--RLGMLVFFGMLGWALLTAMNQ 218 R L R + + + A L + P R R M ++L + Sbjct: 26 RKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEI 82
>PF01206#SirA family protein Length = 76 Score = 92.5 bits (230), Expect = 6e-29 Identities = 16/71 (22%), Positives = 37/71 (52%) Query: 7 DYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCPQSINNIPLDARNHGYTVLDIQQ 66 D LD G CP P + + + + GE+L V++ P S+ + ++ G+ +L+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 67 DGPTIRYLIQK 77 + T + +++ Sbjct: 65 EDGTYHFRLKR 75
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 17/54 (31%), Positives = 27/54 (50%), Gaps = 2/54 (3%) Query: 80 APNYLRRGVASLILRHILQVAQDRCLHRLSLETGTQAGFTACHQLYLKHGFADC 133 A +Y ++GV + +L ++ A++ L LET +ACH Y KH F Sbjct: 98 AKDYRKKGVGTALLHKAIEWAKENHFCGLMLET-QDINISACH-FYAKHHFIIG 149
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 117 bits (294), Expect = 5e-38 Identities = 103/103 (100%), Positives = 103/103 (100%) Query: 2 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 61 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL Sbjct: 1 SAIQGIEGVISQLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTL 60 Query: 62 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 104 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV Sbjct: 61 GEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 756 bits (1953), Expect = 0.0 Identities = 479/555 (86%), Positives = 515/555 (92%), Gaps = 5/555 (0%) Query: 3 ATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAKAPDYRTLFSNLSDQDGGA 62 +TA Q K LEWLNRLRANP+IPLIVAGSAAVA++VA++LWAK PDYRTLFSNLSDQDGGA Sbjct: 5 STATQPKPLEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGA 64 Query: 63 IVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 122 IV+QLTQMNIPYRF+ SGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ Sbjct: 65 IVAQLTQMNIPYRFANGSGAIEVPADKVHELRLRLAQQGLPKGGAVGFELLDQEKFGISQ 124 Query: 123 FSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPSLFVREQKSPSASVTVNLLPGRA 182 FSEQVNYQRALEGEL+RTIET+GPVK ARVHLAMPKPSLFVREQKSPSASVTV L PGRA Sbjct: 125 FSEQVNYQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRA 184 Query: 183 LDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLTQSNTSGRDLNDAQLKYASDVEGRI 242 LDEGQISA+VHLVSSAVAGLPPGNVTLVDQ GHLLTQSNTSGRDLNDAQLK+A+DVE RI Sbjct: 185 LDEGQISAVVHLVSSAVAGLPPGNVTLVDQSGHLLTQSNTSGRDLNDAQLKFANDVESRI 244 Query: 243 QRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTEEQYRPNGDESHAALRSRQLNESEQSG 302 QRRIEAILSPIVGNGN+HAQVTAQLDFA+KEQTEE Y PNGD S A LRSRQLN SEQ G Sbjct: 245 QRRIEAILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVG 304 Query: 303 SGYPGGVPGALSNQPAPANNAPISTPPANQNNRQQ--QASTTSNS---GPRSTQRNETSN 357 +GYPGGVPGALSNQPAP N API+TPP NQ N Q Q ST++NS GPRSTQRNETSN Sbjct: 305 AGYPGGVPGALSNQPAPPNEAPIATPPTNQQNAQNTPQTSTSTNSNSAGPRSTQRNETSN 364 Query: 358 YEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGKPLPLSNEQMKQIEDLTREAMGFSEK 417 YEVDRTIRHTKMNVGD++RLSVAVVVNYKTL DGKPLPL+ +QMKQIEDLTREAMGFS+K Sbjct: 365 YEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKPLPLTADQMKQIEDLTREAMGFSDK 424 Query: 418 RGDSLNVVNSPFNSSDESGGELPFWQQQAFIDQLLAAGRWLLVLLVAWLLWRKAVRPQLT 477 RGD+LNVVNSPF++ D +GGELPFWQQQ+FIDQLLAAGRWLLVL+VAW+LWRKAVRPQLT Sbjct: 425 RGDTLNVVNSPFSAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVAWILWRKAVRPQLT 484 Query: 478 RRAEAMKAVQQQAQAREEVEDAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 537 RR E KA Q+QAQ R+E E+AVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR Sbjct: 485 RRVEEAKAAQEQAQVRQETEEAVEVRLSKDEQLQQRRANQRLGAEVMSQRIREMSDNDPR 544 Query: 538 VVALVIRQWINNDHE 552 VVALVIRQW++NDHE Sbjct: 545 VVALVIRQWMSNDHE 559
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 341 bits (876), Expect = e-119 Identities = 117/329 (35%), Positives = 197/329 (59%), Gaps = 2/329 (0%) Query: 1 MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANVTQISNKQLTDVLAEFE 60 +S LTG K+ ILL++IG + +++VFK+LSQ E+++L+ +A + I+++ +VL EF+ Sbjct: 12 VSALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFK 71 Query: 61 QEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRDTASGIETLNFMEPQSAAD 120 + + DY R +L K+LG ++A ++ + L + + E + +P + + Sbjct: 72 ELMMAQEFIQKGGIDYARELLEKSLGTQKAVDIINN-LGSALQSRPFEFVRRADPANILN 130 Query: 121 LIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLRIATFGGVQPAALAELTEVLN 180 I+ EHPQ IA IL +L +A+ IL+ ++ +V RIA P + E+ VL Sbjct: 131 FIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLE 190 Query: 181 GLLDGQ-NLKRSKMGGVRTAAEIINLMKTQQEEAVITAVREFDGELAQKIIDEMFLFENL 239 L + + GGV EIIN+ + E+ +I ++ E D ELA++I +MF+FE++ Sbjct: 191 KKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDI 250 Query: 240 VDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLRNMSQRAADILRDDLANRGPVRLS 299 V +DDRSIQR+L+E+D + L ALK + P++EK +NMS+RAA +L++D+ GP R Sbjct: 251 VLLDDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRK 310 Query: 300 QVENEQKAILLIVRRLAETGEMVIGSGED 328 VE Q+ I+ ++R+L E GE+VI G + Sbjct: 311 DVEESQQKIVSLIRKLEEQGEIVISRGGE 339
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 377 bits (969), Expect = e-137 Identities = 228/228 (100%), Positives = 228/228 (100%) Query: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI Sbjct: 1 MSDNLPWKTWTPDDLAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQGYQAGI 60 Query: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL Sbjct: 61 AEGRQQGHKQGYQEGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRL 120 Query: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT Sbjct: 121 MQMALEAARQVIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGAT 180 Query: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV Sbjct: 181 LSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGVV 228
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 205 bits (521), Expect = 3e-71 Identities = 147/147 (100%), Positives = 147/147 (100%) Query: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG Sbjct: 1 MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAG 60 Query: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST Sbjct: 61 ITSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQST 120 Query: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147 AALLAENRLDQKKMDEFAQRAAMRKPE Sbjct: 121 AALLAENRLDQKKMDEFAQRAAMRKPE 147
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 475 bits (1224), Expect = e-171 Identities = 375/375 (100%), Positives = 375/375 (100%) Query: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK Sbjct: 1 MIRLAPLITADVDTTTLPGGKASDAAQDFLALLSEALAGETTTDKAAPQLLVATDKPTTK 60 Query: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA Sbjct: 61 GEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAAVADKNTTKDEKA 120 Query: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP Sbjct: 121 DDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKPTLFTKLTSEQLTTAQPDDAP 180 Query: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW Sbjct: 181 GTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPLITPHQTQPLPTVAAPVLSAPLGSHEW 240 Query: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA Sbjct: 241 QQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAA 300 Query: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS Sbjct: 301 LPVLRTQLAESGIQLGQSNISGESFSGQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVS 360 Query: 361 LQGRVTGNSGVDIFA 375 LQGRVTGNSGVDIFA Sbjct: 361 LQGRVTGNSGVDIFA 375
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 381 bits (979), Expect = e-135 Identities = 85/324 (26%), Positives = 147/324 (45%), Gaps = 10/324 (3%) Query: 5 ILSQAEIDALLNGDS--EVKDEPTASVSGESDIRPYDPNTQRRVVRERLQALEIINERFA 62 +LSQ EID LL S + E +S I YD + +E+++ L +++E FA Sbjct: 4 VLSQDEIDQLLTAISSGDASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHETFA 63 Query: 63 RHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNLNLIHLKPLRGTGLVVFSPSL 122 R L LR + V ++ Y EF R++P P+ L +I + PL+G ++ PS+ Sbjct: 64 RLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVDPSI 123 Query: 123 VFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKLALEGYSDAWKAINPLEVEYVRS 182 F +D LFGG G+ KV+ R+ T E V+ ++ L ++W + L + Sbjct: 124 TFSIIDRLFGGTGQ-AAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLGQI 181 Query: 183 EMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNICLPFSMIEPLRELLVNPPLENS--R 240 E +F I P+++VV ++G G N C+P+ IEP+ L + +S R Sbjct: 182 ETNPQFAQI-VPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVRR 240 Query: 241 NEDQNWRDNLVRQVQHSQLELVANFADISLRLSQILKLNPGDVLPIEKP---DRIIAHVD 297 + + L ++ +++VA + L + IL L GD++ + D + + Sbjct: 241 SSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSIG 300 Query: 298 GVPVLTSQYGTLNGQYALRIEHLI 321 Q G + + A +I I Sbjct: 301 NRKKFLCQPGVVGKKIAAQILERI 324
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 213 bits (543), Expect = 8e-75 Identities = 123/137 (89%), Positives = 133/137 (97%) Query: 1 MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAAETVFQQFGGGDVSGTLQDIDLIMDI 60 MSDMNNP+D+N GA+DDLWA+AL+EQK+T++KSAA+ VFQQ GGGDVSG +QDIDLIMDI Sbjct: 1 MSDMNNPSDENTGALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQDIDLIMDI 60 Query: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV Sbjct: 61 PVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGEVVVVADKYGV 120 Query: 121 RITDIITPSERMRRLSR 137 RITDIITPSERMRRLSR Sbjct: 121 RITDIITPSERMRRLSR 137
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 334 bits (858), Expect = e-119 Identities = 245/245 (100%), Positives = 245/245 (100%) Query: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM Sbjct: 1 MRRLLSVAPVLLWLITPLAFAQLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLM 60 Query: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEK 120 Query: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK Sbjct: 121 ISMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELK 180 Query: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA Sbjct: 181 TAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLA 240 Query: 241 QSFYS 245 QSFYS Sbjct: 241 QSFYS 245
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 67.1 bits (164), Expect = 1e-18 Identities = 22/78 (28%), Positives = 42/78 (53%) Query: 4 ESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQINEMTLSFIPKIIAVFIAII 63 + ++ G +A+ + L L+ +VA + GL++ + Q TQ+ E TL F K++ V + + Sbjct: 2 DDLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLF 61 Query: 64 IAGPWMLNLLLDYVRTLF 81 + W +LL Y R + Sbjct: 62 LLSGWYGEVLLSYGRQVI 79
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 204 bits (520), Expect = 2e-67 Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL Sbjct: 61 NDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHL 120 Query: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF Sbjct: 121 NMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLIF 180 Query: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC Sbjct: 181 LNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFC 240 Query: 241 EHLFSEIFNLLADIISELPLI 261 EHLFSEIFNLLADIISELPLI Sbjct: 241 EHLFSEIFNLLADIISELPLI 261
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.045 Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 15/62 (24%) Query: 320 AKYILTPVLWKYLYRYAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRG 379 A+Y + PVLW Y+ R+ K + G+ VY +R +DG+E RG Sbjct: 166 ARYQVGPVLWGYVVRFIK---SDGDKLTLPYVY------------SRSQRDGSEAWKWRG 210 Query: 380 WD 381 WD Sbjct: 211 WD 212
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 34.8 bits (80), Expect = 2e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 9/92 (9%) Query: 37 AQKLAADDDVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPA-- 94 +KLA + + D+ +ILT + +L + Q + EE R+ E F A Sbjct: 219 GEKLAEEVNADIFMILTDV---NGAALYYGTEKEQWLREVKVEELRKYYEE--GHFKAGS 273 Query: 95 --EKIEAVCHAIAAHSFSAQIAPLTTEAKIVQ 124 K+ A I A IA L + ++ Sbjct: 274 MGPKVLAAIRFIEWGGERAIIAHLEKAVEALE 305
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 35/181 (19%), Positives = 61/181 (33%), Gaps = 37/181 (20%) Query: 290 ENILFLARADKNNVLVKLDSLS----------------LNKEVENLLDYL--EYLSDEKE 331 NI L D L SLS L E+ + YL + E Sbjct: 180 NNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239 Query: 332 ICFKVECNQQIFADKI---LLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNSYLNIDIAS 388 + F+ + N I ++ L+Q ++ N I + I P+ +I + D N + +++ + Sbjct: 240 LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKD-NGTVTLEVEN 298 Query: 389 PGTKINEPEKLFRRFWRGDNSRHSVGQGLGLSLVKA-IAELHGGSATYHYLNKHNVFRIT 447 G+ + K G GL V+ + L+G A K Sbjct: 299 TGSLALKNTKE--------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344 Query: 448 L 448 + Sbjct: 345 V 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-20 Identities = 30/117 (25%), Positives = 60/117 (51%), Gaps = 1/117 (0%) Query: 2 KILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDDYALIILDIMLPGMDGWQ 61 IL+ +D+ + + Q LS AGY + S+ D L++ D+++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILQTLRTA-KQTPVICLTARDSVDDRVRGLDSGANDYLVKPFSFSELLARVRAQLRQ 117 +L ++ A PV+ ++A+++ ++ + GA DYL KPF +EL+ + L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>INTIMIN#Intimin signature. Length = 939 Score = 706 bits (1822), Expect = 0.0 Identities = 219/790 (27%), Positives = 349/790 (44%), Gaps = 70/790 (8%) Query: 148 QQIASTSQQIGSLLAEDMNSEQAANMARGWASSQASGAMTDWLSRFGTARITLGVDEDFS 207 QQ AS Q+ S +N + A + A G A +QAS + WL +GTA + L +F Sbjct: 168 QQAASLGSQLQS---RSLNGDYAKDTALGIAGNQASSQLQAWLQHYGTAEVNLQSGNNFD 224 Query: 208 LKNSQFDFLHPWYETPDNLFFSQHTLHRTDERTQINNGLGWRHFTPTWMSGINFFFDHDL 267 S DFL P+Y++ L F Q D R N G G R F P M G N F D D Sbjct: 225 --GSSLDFLLPFYDSEKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDF 282 Query: 268 SRYHSRAGIGAEYWRDYLKLSSNGYLRLTNWRSAPELDNDYEARPANGWDVRAESWLPAW 327 S ++R GIG EYWRDY K S NGY R++ W + DY+ RPANG+D+R +LP++ Sbjct: 283 SGDNTRLGIGGEYWRDYFKSSVNGYFRMSGWHESYN-KKDYDERPANGFDIRFNGYLPSY 341 Query: 328 PHLGGKLVYEQYYGDEVALFDKDDRQSNPHAITAGLNYTPFPLMTFSAEQRQGKQGENDT 387 P LG KL+YEQYYGD VALF+ D QSNP A T G+NYTP PL+T + R G END Sbjct: 342 PALGAKLMYEQYYGDNVALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDL 401 Query: 388 RFAVDFTWQPGSAMQKQLDPNEVAARRSLAGSRYDLVDRNNNIVLEYRKKELVRLTLTDP 447 +++ F +Q +Q++P V R+L+GSRYDLV RNNNI+LEY+K++++ L + Sbjct: 402 LYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPHD 461 Query: 448 VTGKSGEVKSLVSSLQTKYALKGYNVEATALEAAGGKVVTTG----KDILVTLPAYRFTS 503 + G + + +++KY L + +AL + GG++ +G +D LPAY Sbjct: 462 INGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAY---- 517 Query: 504 TPETDNTWPIEVTAEDVKGNLSNREQ-SMVVVQAPTLSQKDSSVSLSTQTLNADSHSTAT 562 N + + A D GN SN ++ V+ + + + +A + T Sbjct: 518 VQGGSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 563 LTFIAH------DAAGNPVVGLVLSTRHEGVQDITLSDWKDNGDGSYTQILTTGAMSGTL 616 +T+ A A PV ++S G ++ + NG G T L + + Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSANTNGSGKATVTLKSDKPGQVV 633 Query: 617 TLMPQLNGVDAAKAPAVVNIISVSSSRTHSSIKIDKDRYLSGNPIEVTVELR-DENDKPV 675 A A AV I + + + IK DK ++ +T ++ + DKPV Sbjct: 634 VSAKTAEMTSALNANAV--IFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPV 691 Query: 676 KEQKQQLNNAVSIDNVKPGVTTDWKETADGVYKATYTAYTKGSGL-TAKLLMQNWNEDLH 734 Q+ + K +T+ K +G K T T+ T G L +A++ + Sbjct: 692 SNQEVTFTTTLG----KLSNSTE-KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAP 746 Query: 735 TAGFIIDANPQSAKIATLSASNNGVLANENAANTVSVNVADEGSNPINDHTVTFAVLSGS 794 F I + G L + + ++ Sbjct: 747 EVEFFTTLTIDDGNIEIVGTGVKGKLPTV---------------------WLQYGQVNLK 785 Query: 795 ATSFNNQNTAKTDVNGLATFDLKSSK---QEDNTVEVTLENGVKQTLIVSFVGDSSTAQV 851 A+ N + T ++ +A+ D S + +E T +++ + QT ++ + + + Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQT--ATYTIATPNSLI 843 Query: 852 DLQKSKNEVVADGNDSVTMTATVRDAKGNLLNDVMVTF----------NVNSAEAKLSQT 901 SK D ++ + N L +V + + + + + QT Sbjct: 844 VPNMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAWGAANKYEYYKSSQTIISWVQQT 903 Query: 902 EVNSHDGIAT 911 ++ G+A+ Sbjct: 904 AQDAKSGVAS 913 Score = 199 bits (508), Expect = 5e-54 Identities = 93/375 (24%), Positives = 151/375 (40%), Gaps = 32/375 (8%) Query: 830 LENGVKQTLIVSFVGDSSTAQ--VDLQKSKNEVVADGNDSVTMTATVRDAKGNLLNDVMV 887 N V T+ V G D K ADG +++T TATV+ N V V Sbjct: 538 SSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQAN-VPV 596 Query: 888 TFNVNSAEAKLSQTEVNSH-DGIATATLTSLKNGDYRVTASVSSGSQANQQVNFIGDQST 946 +FN+ S A LS N++ G AT TL S K G V+A + + A I T Sbjct: 597 SFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQT 656 Query: 947 AALTLSVPSGDITVTNTAPQYMTATLQ-DKNGNPLKDKEITFSVPNDVASKFSISNGGKG 1005 A + + T +T T++ K P+ ++E+TF+ + + Sbjct: 657 KASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVTFT------TTLGKLSNSTE 710 Query: 1006 MTDSNGVAIASLTGTLAGTHMIMARLANSNVSDAQPMTFVADKDRAVVVLQTSKAEIIGN 1065 TD+NG A +LT T G ++ AR+++ V P + + + EI+G Sbjct: 711 KTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEV----EFFTTLTIDDGNIEIVGT 766 Query: 1066 GVDETTLTATVK-DPSNHPVAGITVNFTMPQDVAANFTLENNGIAITQANGEAHVTLKGK 1124 GV T ++ N +G +T + N IA A+ VTLK K Sbjct: 767 GVKGKLPTVWLQYGQVNLKASGGNGKYT--------WRSANPAIASVDAS-SGQVTLKEK 817 Query: 1125 KAGTHTVTATLGNNNTSDSQPVTFVADKASAQVVLQISKDEITGNGVDSATLTATVKDQF 1184 GT T++ +SD+Q T+ ++ +V +SK + V++ Sbjct: 818 --GTTTISVI-----SSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLPSS 870 Query: 1185 DNEVNNLPVTFSSAS 1199 NE+ N+ + +A+ Sbjct: 871 QNELENVFKAWGAAN 885 Score = 87.0 bits (215), Expect = 7e-19 Identities = 91/396 (22%), Positives = 130/396 (32%), Gaps = 51/396 (12%) Query: 1126 AGTHTVTATLGNNNTSDSQPVTFVADKASAQVVLQIS--------KDEITGNGVDSATLT 1177 + + VTA + N + S V S V+ K +G ++ T T Sbjct: 522 SNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYT 581 Query: 1178 ATVKDQFDNEVNNLPVTFSSASSGLTLTPGVSNTNESGIAQATLAGVAFGEKTVTASLAN 1237 ATVK + N PV+F+ S L+ +NTN SG A TL G+ V+A A Sbjct: 582 ATVKKNGVAQANV-PVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAE 640 Query: 1238 NGASDNKTVHFIGDTAAAKIIELAPVPDSIIAGTPQNSSGSVITATV-VDNNGFPVKGVT 1296 ++ N D A I E+ + +A IT TV V PV Sbjct: 641 MTSALNANAVIFVDQTKASITEIKADKTTAVANGQ-----DAITYTVKVMKGDKPVSNQE 695 Query: 1297 VNFTSNAATAEMTNGGQAVTNEQGKATVTYTNTRSSIESGARPDTVEASLENGSSTLSTS 1356 V FT+ + T+ G A VT T+T G S +S Sbjct: 696 VTFTTTLGKLSNS---TEKTDTNGYAKVTLTSTTP-----------------GKSLVSAR 735 Query: 1357 I-NVNADASTAHLTLLQALFDTVSAGETTSLYIEVKDNYGNGVPQQ--EVTLSVSPSEGV 1413 + +V D + L T+ G + G GV + V L Sbjct: 736 VSDVAVDVKAPEVEFFTTL--TIDDGNIEIV--------GTGVKGKLPTVWLQYGQVNLK 785 Query: 1414 TPSNNAIYTTNHDGNFYASFTATKAGV---YQLTATLENGDSMQQTVTYVPNVANAEITL 1470 N YT AS A+ V + T T+ S QT TY N+ I Sbjct: 786 ASGGNGKYTWRSANPAIASVDASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVP 845 Query: 1471 AASKDPVIADNNDLTTLTATVADTEGNAIANTEVTF 1506 SK D + + N + N + Sbjct: 846 NMSKRVTYNDAVNTCKNFGGKLPSSQNELENVFKAW 881 Score = 63.9 bits (155), Expect = 6e-12 Identities = 86/448 (19%), Positives = 154/448 (34%), Gaps = 44/448 (9%) Query: 1441 YQLTATLENGDSMQQTVTYVPNVANAEITLAASKDPVIADNNDLT-----------TLTA 1489 Y + + Q + P N TL+ S+ ++ NN++ + Sbjct: 403 YSMQFRYQFDKPWSQQIE--PQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNIPH 460 Query: 1490 TVADTEGNA---IANTEVTFTLPEDVKANFTL-SDGGKVITDAEGKAK---VTLKGTKAG 1542 + TE + + + L V + L S GG++ A+ L G Sbjct: 461 DINGTERSTQKIQLIVKSKYGLDRIVWDDSALRSQGGQIQHSGSQSAQDYQAILPAYVQG 520 Query: 1543 AH-----TVTASMTGGKS---EQLVVNFIADTLTAQ----VNLNVTEDNFIANNVGMTRL 1590 T A G S L + +++ + + + A+ Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITY 580 Query: 1591 QATVTDGNGNPLANEAVTFTLPADVSASFTLGQGGSAITDINGKAEVTLSGTKSGTYPVT 1650 ATV NG AN V+F + VS + L SA T+ +GKA VTL K G V+ Sbjct: 581 TATVKK-NGVAQANVPVSFNI---VSGTAVLSAN-SANTNGSGKATVTLKSDKPGQVVVS 635 Query: 1651 VSVNNYGVSDTKQVTLIADAGTAKLASLTSVYSFVVSTTEGATMTASVTDANGNPVEGIK 1710 + + D A + + + + V+ + A PV + Sbjct: 636 AKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQE 695 Query: 1711 VNFRGTSVTLSSTSVETDDRGFAEILVTSTEVGLKTVSASLADKPTEVISRLLNASADVN 1770 V F T LS+++ +TD G+A++ +TST G VSA ++D +V + + + Sbjct: 696 VTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFFTTL- 754 Query: 1771 SATITSLEIPEGQVMVAQDVAVKAHVNDQFGNPVAHQPVTFSAEPSSQMI----ISQNTV 1826 TI I V + Q + ++ ++ I S V Sbjct: 755 --TIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQV 812 Query: 1827 STNTQGVAEVTMTPERNGSYMVKASLPN 1854 + +G +++ N + + PN Sbjct: 813 TLKEKGTTTISVISSDNQTATYTIATPN 840 Score = 55.8 bits (134), Expect = 2e-09 Identities = 44/161 (27%), Positives = 63/161 (39%), Gaps = 5/161 (3%) Query: 1887 TLTATLTSANGTPVEGQVINFSVTPEGATLSGGKVRTNSSGQAPVVLTSNKVGTYTVTAS 1946 T TAT+ NG ++F++ A LS TN SG+A V L S+K G V+A Sbjct: 579 TYTATVKK-NGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAK 637 Query: 1947 FHNGVTIQTQTTVKVTGNSSTAHVASFIADPSTIAATNTDLSTLKATVEDGSGNLIEGLT 2006 + + + + A + AD +T A D T V G + Sbjct: 638 TAEMTS-ALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKVMKG-DKPVSNQE 695 Query: 2007 VYFALKSGSATLTSLTAVTDQNGIATTSVKGAMTGSVTVSA 2047 V F G + + T TD NG A ++ G VSA Sbjct: 696 VTFTTTLGKLSNS--TEKTDTNGYAKVTLTSTTPGKSLVSA 734
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 38/259 (14%), Positives = 95/259 (36%), Gaps = 18/259 (6%) Query: 79 LGGVIFGHFGDRLGRKRMLMLTVWMMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFA 138 +G ++G D+LG KR+L+ + + + + + SF ++ I+ ++ A Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSL----LIMARFIQGAGAAA 119 Query: 139 VGGEWGGAALLSVESAPKNKK-AFYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWG 197 + + K S V +G GVG + + I Sbjct: 120 FPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------------H 167 Query: 198 WRIPFLFSIVLVLGALWVRNGMEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIA 257 W L ++ ++ ++ +++ + + + ++ +L + + Sbjct: 168 WSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLI 227 Query: 258 LRLCELLTMYIVTAFALNYSTQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRR 317 + + L +++ + + GL + + IG+L GG+ T+ F + + Sbjct: 228 VSVLSFL-IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV 286 Query: 318 VYITGTLIGTLSAFPFFMA 336 ++ IG++ FP M+ Sbjct: 287 HQLSTAEIGSVIIFPGTMS 305
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 41.6 bits (97), Expect = 2e-05 Identities = 121/616 (19%), Positives = 195/616 (31%), Gaps = 75/616 (12%) Query: 321 TVTGINRLGAFSVVEGKADNVVLENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTATTVS 380 VT + GA + V + + +GG + G A + R Sbjct: 207 NVTAVPASGAPAAVSVLGASELTLDGGH--ITGGRAAGVAAMQGAVVHLQRATIRRGDAP 264 Query: 381 MGNGGVLLADSGAAVSGTRSDGKAFSIGGGQA----DALMLEKGSSFTLNAGDTATDTTV 436 G A G AV G G + G +E S A Sbjct: 265 AGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVG 324 Query: 437 NGGLFTARGGTLAGTTTLNNGAILTLSGKTV---NNDTLTIR-EGDALLQGGSLTGNGSV 492 G T GG+L+ G ++ G L+I + A QG +L Sbjct: 325 RGARVTVSGGSLSAPH----GNVIETGGARRFAPQAAPLSITLQAGAHAQGKALLYRVLP 380 Query: 493 EKSGSGTLTVSNTTLTQKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDP 552 E LT++ Q + E S DV GA Sbjct: 381 EPV---KLTLTGGADAQGDIVATELPSIPGTSIGPLDVALASQARWT--------GATRA 429 Query: 553 TNVTLASGATWNIPDNATVQSVVDDLSHAGQIHF-TSTRTGKFVPATLKVKNLNGQNGTI 611 + ATW + DN+ V ++ L+ G + F G+F L V L G +G Sbjct: 430 VDSLSIDNATWVMTDNSNVGAL--RLASDGSVDFQQPAEAGRF--KVLTVNTLAG-SGLF 484 Query: 612 SLRVRPDMAQNNADRLVIDGGRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTE 671 + V D+ + D+LV+ A+G+ L + N+G+ + T + V + A T Sbjct: 485 RMNVFADLGLS--DKLVVMQD-ASGQHRLWVRNSGSEPASANTL---LLVQTPLGSAATF 538 Query: 672 EGAFVQGNRLQAGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRIVAGSR 731 A ++ G + Y L + + W L A A P Sbjct: 539 TLANK-DGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPA 597 Query: 732 SHQTGVNGENNSVRLSIQGGHLGHDNNGGIARG-----------ATPESSGSYG--FVRL 778 + + ++ G +G + A P++ G++G F + Sbjct: 598 PQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQR 657 Query: 779 E------GDLMRTEVAG--------MSVTAGVYGAAGHSSVDVKDDDGSRAGTVRDDAGS 824 + G +VAG ++V G + G + D + G D+ Sbjct: 658 QQLDNRAGRRFDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTDSVH 717 Query: 825 LGGYLNLVHTSSGLWADIVAQGTRHSMKASSDNND-------FRARGWGWLGSLETGLPF 877 +GGY + SG + D + +R +D +R G G SLE G F Sbjct: 718 VGGYATYI-ADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGA--SLEAGRRF 774 Query: 878 SITDNLMLEPQLQYTW 893 + D LEPQ + Sbjct: 775 THADGWFLEPQAELAV 790
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.1 bits (112), Expect = 4e-08 Identities = 30/167 (17%), Positives = 62/167 (37%), Gaps = 27/167 (16%) Query: 1 MNILLFGKTGQVGWELQRALAPLGN-LIAFDVHSTDY--------------------CGD 39 M L+ G G +G+ + + L G+ ++ D + Y D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 40 FSNPEGVAETVRSIRPDIIVNAAAHTAVDKAESEPEF---AQLINATSVEAIAKAANEVG 96 ++ EG+ + S + + + AV + P + L ++ + + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK-IQ 119 Query: 97 AWVIHYSTDYVFPGNGDMPWLETDATA-PLNVYGETKLAGEKALQEY 142 +++ S+ V+ N MP+ D+ P+++Y TK A E Y Sbjct: 120 H-LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTY 165
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 183 bits (465), Expect = 4e-57 Identities = 87/360 (24%), Positives = 149/360 (41%), Gaps = 48/360 (13%) Query: 1 MKILVTGGAGFIGSAVVRHIINNTQDSVVNVDKLT--YAGN-RESLADVSDSERYVFEHA 57 MK LVTG AGFIG V + ++ VV +D L Y + +++ ++ + F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DICDAPAMARIFAQHQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYVLLEAARNYWSA 117 D+ D M +FA + V V S+ P A+ ++N+ G +LE R+ Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LDSDKKNSFRFHHISTDEVYGDLPHPDEVNNTEELPLFTETTAYAPSSPYSASKASSDHL 177 + S+ VYG ++P T+ + P S Y+A+K +++ + Sbjct: 117 ------KIQHLLYASSSSVYGL---------NRKMPFSTDDSVDHPVSLYAATKKANELM 161 Query: 178 VRAWKRTYGLPTIVTNCSNNYGPYHFPEKLIPLVILNALEGKALPIYGKGDQIRDWLYVE 237 + YGLP YGP+ P+ + LEGK++ +Y G RD+ Y++ Sbjct: 162 AHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYID 221 Query: 238 D-------------HARALYTVVTEGKA-----GETYNIGGHNEKKNIDVVLTICDLLDE 279 D HA +TV T A YNIG + + +D + + D L Sbjct: 222 DIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG- 280 Query: 280 IVPKEKSYREQITYVADRPGHDRRYAIDAEKIGRALGWKPQETFESGIRKTVEWYLSNTK 339 + +K+ +PG + D + + +G+ P+ T + G++ V WY K Sbjct: 281 -IEAKKNMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 86.4 bits (214), Expect = 2e-21 Identities = 66/344 (19%), Positives = 132/344 (38%), Gaps = 47/344 (13%) Query: 5 RVFIAGHRGMVGSAIRRQLEQRG-------------DVEL------VLRTRD----ELNL 41 + + G G +G + ++L + G DV L +L +++L Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 42 LDSRAVHDFFASERIDQVYLAAAKVGGIVANNTYPADFIYQNMMIESNIIHAAHQNDVNK 101 D + D FAS ++V+++ + + + P + N+ NI+ N + Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 102 LLFLGSSCIYPKLAKQPMAESELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYGRDYRSV 161 LL+ SS +Y K P + P + YA K A + +Y+ YG + Sbjct: 121 LLYASSSSVYGLNRKMPFSTD---DSVDHPVS-LYAATKKANELMAHTYSHLYGLPATGL 176 Query: 162 MPTNLYGPHDNFHPSNSHVIPALLRRFHEATAQNAPDVVVWGSGTPMREFLHVDDMAAAS 221 +YGP P L +F +A + + V+ G R+F ++DD+A A Sbjct: 177 RFFTVYGPWGR--PD------MALFKFTKAMLEGKS-IDVYNYGKMKRDFTYIDDIAEAI 227 Query: 222 IHVMELAH----EVWLENTQPMLSH-----INVGTGVDCTIRELAQTIAKVVGYKGRVVF 272 I + ++ + +E P S N+G + + Q + +G + + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 273 DASKPDGTPRKLLDVTRLHQ-LGWYHEISLEAGLASTYQWFLEN 315 +P D L++ +G+ E +++ G+ + W+ + Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 104 bits (262), Expect = 1e-27 Identities = 76/353 (21%), Positives = 122/353 (34%), Gaps = 42/353 (11%) Query: 6 LITGVTGQDGSYLAEFLLEKGYEVHGIKRRASSFNTERVDHIYQDPH--------TCNPK 57 L+TG G G ++++ LLE G++V GI + N Y D P Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGI----DNLND------YYDVSLKQARLELLAQPG 53 Query: 58 FHLHYGDLSDTSNLTRILREVQPDEVYNLGAMSHVAVSFESPEYTADVDAMGTLRLLEAI 117 F H DL+D +T + + V+ V S E+P AD + G L +LE Sbjct: 54 FQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGC 113 Query: 118 RFLGLEKKTRFYQASTSELYGLVQEIPQKETTPF-YPRSPYAVAKLYAYWITVNYRESYG 176 R ++ AS+S +YGL +++P +P S YA K + Y YG Sbjct: 114 RHNKIQ---HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYG 170 Query: 177 MYACNGILFNHESPRRGETFVTRKITRAIANIAQGLESCLYLGNMDSLRDWGHAKDYVKM 236 + A F P K T+A+ G +Y RD+ + D + Sbjct: 171 LPATGLRFFTVYGPWGRPDMALFKFTKAMLE---GKSIDVY-NYGKMKRDFTYIDDIAEA 226 Query: 237 QWMMLQQEQPEDFVIATGVQYSVRQFVEMAAAQLGIKLRFEGTGVEEKGIVVSVTGHDAP 296 + D +G + E + DA Sbjct: 227 IIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIG------NSSPVELMDYIQAL-EDAL 279 Query: 297 GVKPGDVIIAVDPRY--FRPAEVETLLGDPTKAHEKLGWKPEITLREMVSEMV 347 G++ +P +V D +E +G+ PE T+++ V V Sbjct: 280 GIE-------AKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 33.9 bits (77), Expect = 7e-04 Identities = 22/92 (23%), Positives = 36/92 (39%), Gaps = 2/92 (2%) Query: 156 AQGCENKNVIIIGAGT-IGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSE 214 A+G E K I GA IG + + GA + A+D + EKL S + ++ Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAH-IAAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 215 MSAPQMQSVLRELRFNQLILETAGVPQTVELA 246 A S + ++ E + V +A Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVA 93
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 36.0 bits (83), Expect = 2e-04 Identities = 53/268 (19%), Positives = 89/268 (33%), Gaps = 17/268 (6%) Query: 29 LSKSGFSAGEIGWSYACTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGALLMYFAAQQ 88 L S G A A+ ++G+++DRF ++ + ++ AGA + Y Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAI--- 89 Query: 89 TTFAGFFPLLLAYSLTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIG-WIASGLACGF 147 A F +L + T A T ++A A + D+ R R G + G+ G Sbjct: 90 MATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG- 147 Query: 148 LPQILGY-ADISPTNIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILL 206 P + G SP + P A + L + FL K + + L A Sbjct: 148 -PVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRW 205 Query: 207 RDKN------FLVFFFCSFLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFML 260 VFF + +P A + IF G + + Sbjct: 206 ARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAM 265 Query: 261 ALPFFTKRFGIKKVLLLGLVTAAIRYGF 288 R G ++ L+LG++ Y Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYIL 293 Score = 34.0 bits (78), Expect = 0.001 Identities = 32/153 (20%), Positives = 53/153 (34%), Gaps = 20/153 (13%) Query: 253 FSEIFFMLALPFFTKRFGIKKVLLLGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGV 312 + L + RFG + VLL+ L AA+ Y +L++G ++ G+ Sbjct: 54 LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAP-----FLWVLYIGRIVAGI 108 Query: 313 SYDFYYVTAYIYVDKKAPVHMRTAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVN 372 + V D R G ++ C GFG + G LGG+M F+ P Sbjct: 109 TGATGAVAGAYIAD-ITDGDERARHFGFMS-ACFGFGMVAGPVLGGLMGG--FSPHAP-- 162 Query: 373 GLTFNWSGMWTFGAVMIAIIAVLFMIFFRESDN 405 + A + + + ES Sbjct: 163 ---------FFAAAALNGLNFLTGCFLLPESHK 186
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 27.9 bits (62), Expect = 0.007 Identities = 13/42 (30%), Positives = 21/42 (50%), Gaps = 1/42 (2%) Query: 6 KMLLGALLLVTSAAWAAPATAGSTNTSGISKYE-LSSFIADF 46 ++L G LLL++S +WA ++K E L + DF Sbjct: 11 RVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDF 52
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 715 bits (1846), Expect = 0.0 Identities = 240/843 (28%), Positives = 392/843 (46%), Gaps = 35/843 (4%) Query: 2 LRMTPLASAI---VALLLGIEAYAAEETFDTHFMIGGMKDQQVANIRL--DDNQPLPGQY 56 R+ + A +AE F+ F+ Q VA++ + + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADD--PQAVADLSRFENGQELPPGTY 78 Query: 57 DIDIYVNKQWRGKYEIIVKDNPQET----CLSREVIKRLGIN-----SDNFASGKQCLTF 107 +DIY+N + ++ E CL+R + +G+N N + C+ Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 108 EQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYLSQYYSDY 167 ++ + D+G RL+ ++PQA++ GY+PPE W+ GINA +Y S Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQN 198 Query: 168 KASGNNKSTYVRFNSGLNLLGWQLHSDASFSKTNNNPGV-----WKSNTLYLERGFAQLL 222 + GN+ Y+ SGLN+ W+L + ++S +++ W+ +LER L Sbjct: 199 RIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLR 258 Query: 223 GTLRVGDMYTSSDIFDSVRFRGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVTIEQNGF 282 L +GD YT DIFD + FRG +L D MLP+S++ F P + GIA+ A VTI+QNG+ Sbjct: 259 SRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGY 318 Query: 283 VVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQPGVSKYDL 342 +Y VPPGPF I D+ AG DL V++KEADGS + VPY++VP + + G ++Y + Sbjct: 319 DIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSI 378 Query: 343 AAGRSHIEGASKQSD-FVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGAGWNT-RIGAIS 400 AG A ++ F Q+ +G T+YGG+ +A+ Y AF G G N +GA+S Sbjct: 379 TAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALS 438 Query: 401 VDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRTFNDHVWANNK 460 VD T+++S + DGQS + YNK ++++ T L +RYS+ Y F D ++ Sbjct: 439 VDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMN 498 Query: 461 DNYRRDENDVYDI----ADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLWRDYWGRSG 516 ++ V + DYY + ++ ++Q L ++ LS + YWG S Sbjct: 499 GYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSN 557 Query: 517 SSKDYQLSYSNNLRRISYTLAASQAYDENHHE-EKRFNIFISIPFD--WGDDVSTPRRQI 573 + +Q + I++TL+ S + ++ + ++IPF D + R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHA 617 Query: 574 YMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGN---ETTAGANLTWNAPV 630 S S + D G +N G+ GT+ + +Y V + G+ +T A L + Sbjct: 618 SASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGY 677 Query: 631 ATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDAYVNGQKYR 690 N YS S +Q VSGG++A + GV L L++T ++ APG KDA V Q Sbjct: 678 GNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGV 737 Query: 691 TTNRNGVVIYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVLVNFDTDQRKP 750 T+ G + T YREN + LD + +L P RGA+V F + Sbjct: 738 RTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA-RVGI 796 Query: 751 WFIKALRADGQSLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVNVAIDKQQGLSCT 810 + L + + L FG V + G+V Q+++ + V V +++ C Sbjct: 797 KLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHCV 856 Query: 811 ITF 813 + Sbjct: 857 ANY 859
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.8 bits (150), Expect = 2e-13 Identities = 22/113 (19%), Positives = 46/113 (40%), Gaps = 2/113 (1%) Query: 9 VMIVDDHPLMRRGVRQLLELDPGSEVVAEAGDGASAIDLANRLDIDVILLDLNMKGMSGL 68 +++ DD +R + Q L G +V + A+ D D+++ D+ M + Sbjct: 6 ILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 69 DTLNALRRDGVTAQIIILTVSDASSDVFALIDAGADGYLLKDSDPEVLLEAIR 121 D L +++ +++++ + + GA YL K D L+ I Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 28.0 bits (62), Expect = 0.008 Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%) Query: 34 KHIVLWLGLALACLGLAMVLWLLVL-QNVPV 63 + I+ +L + L C LAM+ W + L N PV Sbjct: 15 RRILFYLLMLLFCQQLAMIFWRIGLPDNAPV 45
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 30.2 bits (68), Expect = 0.016 Identities = 19/124 (15%), Positives = 47/124 (37%), Gaps = 20/124 (16%) Query: 339 EMHNGKLTIVG-----RLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEF--- 390 E +G + G +++ + + ++++ + H +++ + + + ++ Sbjct: 19 ESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDAIKLVLDALVNSDYGVI 78 Query: 391 ---------GHRPVAVMEYDHESVDLSEWVKDKLARFQQPVRWLTLPPELKNGGIKISRQ 441 GHR V EY SV +++ V + + L P + GIK Q Sbjct: 79 KDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDC-IELAPLHNPANI--EGIKACTQ 135 Query: 442 ALKE 445 + + Sbjct: 136 IMPD 139
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 34.8 bits (80), Expect = 6e-05 Identities = 14/79 (17%), Positives = 32/79 (40%), Gaps = 12/79 (15%) Query: 1 MIEWQDLHHSELSVSQLYALLQLRCAVFV--------VEQNCPYQDIDGDDLTGDNRHIL 52 M+E D++H+ LS ++ L LR F + D + + ++ Sbjct: 1 MLEIFDVNHTLLSETKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNN----NTTYLF 56 Query: 53 GWKNDELVAYARILKSDDD 71 G K++ ++ R +++ Sbjct: 57 GIKDNTVICSLRFIETKYP 75
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 29.9 bits (67), Expect = 0.007 Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 91 NGISIEDQDFAANLFRVARKCLSTGRLDDALPLLQRATEQLPEVSEYWLALAIQYRRCKK 150 N IS + + L+ +A +G+ +DA + Q S ++L L + + Sbjct: 29 NEISSDTLE---QLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQ 85 Query: 151 TEAAAQA 157 + A + Sbjct: 86 YDLAIHS 92
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 406 bits (1046), Expect = e-148 Identities = 249/251 (99%), Positives = 249/251 (99%) Query: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR Sbjct: 1 MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWR 60 Query: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM Sbjct: 61 DYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGM 120 Query: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADGFYPVLSWLTWPM 180 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMAD YPVLSWLTWPM Sbjct: 121 ANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPM 180 Query: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA Sbjct: 181 SVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKPQENPNAQA 240 Query: 241 IQDDLKDIDSE 251 IQDDLKDIDSE Sbjct: 241 IQDDLKDIDSE 251
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 121 bits (306), Expect = 4e-32 Identities = 92/404 (22%), Positives = 167/404 (41%), Gaps = 17/404 (4%) Query: 19 VTIALSLATFMQMLDSTISNVAIPTISGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQ 78 + I L + +F +L+ + NV++P I+ WV T+F + +I V G+L+ Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 79 RIGELRLFLLSVTFFSLSSLMCSLS-TNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPP 137 ++G RL L + S++ + + +LI R +QG A L ++ R P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 138 EKRTFALALWSMTVIIAPICGPILGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRE 197 E R A L V + GP +GG I W +L+ +PM I+ L L +E Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 198 TETSPVKMNLPGLTLLVLGVGGLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWES 257 ++ G+ L+ +G+ + ML F +S I +VSV+S + V Sbjct: 193 VRIKG-HFDIKGIILMSVGI--VFFML--------FTTSYSISFLIVSVLSFLIFVKHIR 241 Query: 258 TSENPILDLSLFKSRNFTIGIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPI 317 +P +D L K+ F IG++ + +G + ++P ++++ + G Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 318 GIMPLLIS-PLIGRYGNKIDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQG 376 G M ++I + G ++ ++ +V + S T F II+ G Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 377 FAVACFFLPLTTISFSGLPDNKFANASSMSNFFRTLSGSVGTSL 420 + ++TI S L + S+ NF LS G ++ Sbjct: 362 LSFTK--TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 78.3 bits (193), Expect = 6e-18 Identities = 62/412 (15%), Positives = 122/412 (29%), Gaps = 96/412 (23%) Query: 13 RRKYFSLLAVVLFIAFSGAYAYWSMELEDMISTDDAYVT-GNADPISAQVSGSVTVVNHK 71 RR ++ F+ + + ++E + + + G + I + V + K Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLG-QVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 72 DTNYVRQGDILVSLDKTDATIALNKA---------------------------------- 97 + VR+GD+L+ L A K Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 98 ------------------KNNLANIVRQTNKLYLQDKQYSAEVASARIQ---YQQSLEDY 136 K + Q + L + AE + + Y+ Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 137 NRRV----PLAKQGVISKE----------TLEHTKDTLISSKAALNAAIQAYKANKALVM 182 R+ L + I+K + S + + I + K LV Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 183 N-------TPLNR-QPQVVEAADATKEAWLALKRTDIKSPVTGYIAQRSVQ-VGETVSPG 233 L + + + + + I++PV+ + Q V G V+ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 234 QSLMAVVPARQ-MWVNANFKETQLTDVRIGQSVNIISDLYGENVVFHGRVTGINMGTGNA 292 ++LM +VP + V A + + + +GQ+ I + F G +G Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVE------AFPYTRYGYLVGK--- 404 Query: 293 FSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEH----PLRIGLSMTATIDT 340 + + +V V +S++ L PL G+++TA I T Sbjct: 405 VKNINLDAIEDQRLGLVFNVI--ISIEENCLSTGNKNIPLSSGMAVTAEIKT 454
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.1 bits (117), Expect = 3e-09 Identities = 22/148 (14%), Positives = 53/148 (35%), Gaps = 31/148 (20%) Query: 4 IIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETLKPDIVIIDVDIPGVNGIQV 63 ++ DD + L + ++ + + + + D+V+ DV +P N + Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRIT-SNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSKKEGMNNIIAAIEAAKNGYCYF 123 L ++K + ++++SA+N + AI+A++ G + Sbjct: 66 LPRIKKARPDLPVLVMSAQNT------------------------FMTAIKASEKGAYDY 101 Query: 124 ---PFSLNRFVGSLTSDQQKLDSLSKQE 148 PF L + + L ++ Sbjct: 102 LPKPFDLTE---LIGIIGRALAEPKRRP 126
>PF04605#Virulence-associated protein D (VapD) Length = 125 Score = 26.4 bits (58), Expect = 0.049 Identities = 15/73 (20%), Positives = 22/73 (30%), Gaps = 13/73 (17%) Query: 15 TNKSPRNAATCRGRYEKQAKG----EFLMSDMLAVEQETNND---------VRQFLNKIN 61 T+K P N K K + + E + F K+ Sbjct: 49 TSKEPINERRVIRIVNKLTKKFTWLGECVKEFDITEIGEQYSLKETIQDLCAKDFHQKLK 108 Query: 62 ELRNKAPKNEETK 74 E K PKN++ K Sbjct: 109 EFTEKTPKNQKLK 121
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 28.0 bits (62), Expect = 0.023 Identities = 17/105 (16%), Positives = 40/105 (38%), Gaps = 15/105 (14%) Query: 94 MKGVMNDKTRFHADKWVGYSKVLAW-----VSLSHKDTFTGA---------KRFQYFQTM 139 M+G ++ +T ++ K + K + W + L D + + QT+ Sbjct: 81 MQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQTL 140 Query: 140 -YDMERQINANLPVGGLPNVDTERTGKLFQRDDFSEDSHANDPKL 183 Y++ + +GG + + ++ Q++ SE N + Sbjct: 141 GYNIGGNFQSAPSLGGNGSFNYSKSISYTQQNYVSEVEQQNSKSV 185
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.5 bits (121), Expect = 2e-09 Identities = 33/116 (28%), Positives = 50/116 (43%), Gaps = 9/116 (7%) Query: 63 VRDGIVWDFFGAVTIVRRHLD-TLEQQFGRRFSHAATSFPPGTDP---RISINVLESAGL 118 ++DG++ DFF +++ + F R P G R + AG Sbjct: 76 MKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGA 135 Query: 119 EVSHVLDEPTAVA---DLLQLDNAG--VVDIGGGTTGIAIVKKGKVTYSADEATGG 169 +++EP A A L + G VVDIGGGTT +A++ V YS+ GG Sbjct: 136 REVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLNGVVYSSSVRIGG 191
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 114 bits (288), Expect = 5e-30 Identities = 81/371 (21%), Positives = 144/371 (38%), Gaps = 74/371 (19%) Query: 23 GIDLGTTNSLVATVRSGQAETLADHEGRHLLPSVVHYQQQGHS-------VGYDARTNAA 75 IDLGT N+L+ G + +E PSVV +Q VG+DA+ Sbjct: 14 SIDLGTANTLIYVKGQG----IVLNE-----PSVVAIRQDRAGSPKSVAAVGHDAK-QML 63 Query: 76 LDTANTISSVKRLMGRSLADIQQRYPHLPYQFQASENGLPMIETAAGLLNPVRVSADILK 135 T I++++ + +AD V+ +L+ Sbjct: 64 GRTPGNIAAIRPMKDGVIADF-------------------------------FVTEKMLQ 92 Query: 136 ALAARATEALAGE-LDGVVITVPAYFDDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYG 194 + V++ VP +R+ +++A+ AG + L+ EP AAAI G Sbjct: 93 HFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAG 152 Query: 195 LDSGQEGVIAVYDLGGGTFDISILRLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAG 254 L + V D+GGGT +++++ L+ V +GGD FD + +Y+R G Sbjct: 153 LPVSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 255 --IPDRSDNRVQRELLDAAIAAKIALSDADSVTVNVAG---WQG-----EISREQFNELI 304 I + + R++ E+ A + + V G +G ++ + E + Sbjct: 208 SLIGEATAERIKHEI-------GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEAL 260 Query: 305 APLVKRTLLACRRALKDAGVE-ADEVLE--VVMVGGSTRVPLVRERVGEFFGRPPLTSID 361 + + A AL+ E A ++ E +V+ GG + + + E G P + + D Sbjct: 261 QEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAED 320 Query: 362 PDKVVAIGAAI 372 P VA G Sbjct: 321 PLTCVARGGGK 331
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 26.3 bits (58), Expect = 0.032 Identities = 23/87 (26%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 4 KTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVSKIRV--GMTQQQVAYALGT 61 K + AVL + AG LER ++ Q + + + VS+ + GMT ++ A Sbjct: 69 KVV-LCGAVLARVDAGDEQLERKIH---YRQQDLVDYSPVSEKHLADGMTVGELCAA--A 122 Query: 62 PLMSDPFGTNTWFYVFRQQPGHEGVTQ 88 MSD N + G G+T Sbjct: 123 ITMSDNSAANL---LLATVGGPAGLTA 146
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 24.5 bits (53), Expect = 0.049 Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 11/48 (22%) Query: 19 TGVSD-SLTALT--LATVAALLTGGGAAGAASVALTPFVGVPVGIFVG 63 TG D SLT ++ LA+V++ G AA S+ VG PV VG Sbjct: 361 TGAIDASLTTISTVLASVSS---GISAAATTSL-----VGAPVSALVG 400
>PF07675#Cleaved Adhesin Length = 1358 Score = 26.2 bits (57), Expect = 0.014 Identities = 11/36 (30%), Positives = 14/36 (38%), Gaps = 1/36 (2%) Query: 31 INVDRVPEAAEALRAQG-FRQLPVVIAGDLSWSGFR 65 V PEA R QG + Q V + + FR Sbjct: 750 KTVVTAPEAIRGTRVQGTWYQKTVQLPAGTKYVAFR 785
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.014 Identities = 20/105 (19%), Positives = 35/105 (33%), Gaps = 17/105 (16%) Query: 1 MKPRQRQAAILEYLQKQGKCSVEEL-----AQYFDTTGTTIRKDLVILEHAGTVIRTYGG 55 M QR I E + + +EL ++ T T+ +D+ E + T G Sbjct: 1 MNKGQRHIKIREIITANEIETQDELVDILKKDGYNVTQATVSRDIK--ELHLVKVPTNNG 58 Query: 56 ---VVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIIL 97 L ++ P+ K + +A V I+L Sbjct: 59 SYKYSLPADQRFNPLS-------KLKRSLMDAFVKIDSASHLIVL 96
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 374 bits (961), Expect = e-127 Identities = 125/388 (32%), Positives = 196/388 (50%), Gaps = 33/388 (8%) Query: 149 IAALAAGALS----------NALLIEQLESQNMLPGDATPFEAVKQTQMIGLSPGMTQLK 198 I A GA +I + ++ ++ ++G S M ++ Sbjct: 91 IKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY 150 Query: 199 KEIEIVAASDLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAALPESVAESELFG 258 + + + +DL ++I+GE+GTGKELVA+A+H+ R P V +N AA+P + ESELFG Sbjct: 151 RVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFG 210 Query: 259 HVKGAFTGAISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRCLR 318 H KGAFTGA + +G+FE A+ GTLFLDEIG++ + Q +LLRVLQ G+ VG +R Sbjct: 211 HEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 319 VDVRVLAATNRDLREEVLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRL 378 DVR++AATN+DL++ + G FR DL++RL+V PL +PPLR+R +D+ L +F +Q Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE- 329 Query: 379 RQGLSRVVLSAGARNLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVIL-----EAQH 433 ++GL A L++ + +PGNVRELE+ + R L E+I E Sbjct: 330 KEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPD 389 Query: 434 FAFPEVTLPTPEVAAVPVVKQNLR-----------------EATEAFQRETIRQALAQNH 476 + + ++ V++N+R + I AL Sbjct: 390 SPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATR 449 Query: 477 HNWAACARMLETDVANLHRLAKRLGLKD 504 N A +L + L + + LG+ Sbjct: 450 GNQIKAADLLGLNRNTLRKKIRELGVSV 477
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.036 Identities = 17/93 (18%), Positives = 29/93 (31%), Gaps = 7/93 (7%) Query: 3 TTMLEVAKRAGVSKATVSRVLSG-----NGYVSQETKDRVFQAVEESGYRPNLLARNLSA 57 T++ E+AK AGV++ + + + +E P L Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 58 KSTQTLGLVVTNTLYHGIYFSELLFHAARMAEE 90 L VT + E++FH E Sbjct: 92 ILIHVLESTVTEERRRLLM--EIIFHKCEFVGE 122
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 29.5 bits (66), Expect = 0.034 Identities = 22/130 (16%), Positives = 40/130 (30%), Gaps = 16/130 (12%) Query: 303 SAPSWTQISRVVVDKIIQNENGNRVAAVVNQ-FRNIAPQSPLELIMGGYRNNQASILERR 361 +A QI + + + ++ VVN F + EL Q S +++ Sbjct: 404 TADQMKQIEDLTREAMGFSDKRGDTLNVVNSPFSAVDNTGG-ELPF----WQQQSFIDQ- 457 Query: 362 HDVLMFNQGWQQYGNVINEIVTVGLGYKTALRKALYTFAEGFKNKDFKGAGVSVHETAER 421 G + +V + ++ A+R L E K + E A Sbjct: 458 ---------LLAAGRWLLVLVVAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEEAVE 508 Query: 422 HFYRQSELLI 431 + E L Sbjct: 509 VRLSKDEQLQ 518
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 55.7 bits (134), Expect = 2e-10 Identities = 39/167 (23%), Positives = 69/167 (41%), Gaps = 1/167 (0%) Query: 38 LDIGVIAGALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAI 97 L+ V+ +LP I + F WV ++ ML +IG G LS +LG K L+ G I Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 98 LFVLGSIGSAFATS-VEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLM 156 + GS+ S +LI AR + G + ++ + RGK + + Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 157 VTLGIVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPR 203 V +G + ++ +W +L + + + + L+ L R Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR 194
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 111 bits (278), Expect = 1e-31 Identities = 72/257 (28%), Positives = 129/257 (50%), Gaps = 11/257 (4%) Query: 3 LSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGIN-IVEPTETIEQ-VTALGRRFL 60 ++A +EGK+A +TG G+G+ +A LA G I ++ E E + + A R Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 61 SLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDALEFSEKDWDDVMNLNIKSV 120 + AD+R I + R E G IDILVN AG++R S+++W+ ++N V Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 121 FFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTASKSGVMGVTRLMANEWAKHN 180 F S++ +K+ + + G I+ + S + + +Y +SK+ + T+ + E A++N Sbjct: 121 FNASRSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 181 INVNAIAPGYMATNNTQQLRADEQRSAEILD--------RIPAGRWGLPSDLMGPIVFLA 232 I N ++PG T+ L ADE + +++ IP + PSD+ ++FL Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 233 SSASDYVNGYTIAVDGG 249 S + ++ + + VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 70.7 bits (173), Expect = 4e-18 Identities = 28/164 (17%), Positives = 65/164 (39%), Gaps = 9/164 (5%) Query: 1 MSTETIEIFNNSDEWANQLKHALSKGENLALLHGLTPDILDRIYAYAFDYHEKGNITDAE 60 M ET + + E+ ++ L G +A+L+ ++ D L+++Y+ AF+ ++ G DA Sbjct: 1 MQQETTD----TQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSLAFNQYQSGKYEDAH 56 Query: 61 IYYKFLCIYAFENHEYLKDFASVCQPKKKYQQAYDLYKLSYNYFPYDDYSVIYRMGQCQI 120 ++ LC+ + + + Q +Y A Y + + +C + Sbjct: 57 KVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI-KEPRFPFHAAECLL 115 Query: 121 GAKNIDNAMQCFYH----IINNCEDDSVKSKAQAYIELLNDNSE 160 + A + I + E + ++ + +E + E Sbjct: 116 QKGELAEAESGLFLAQELIADKTEFKELSTRVSSMLEAIKLKKE 159
>FIMBRIALPAPE#Escherichia coli: P pili tip fibrillum papE protein signature. Length = 173 Score = 28.1 bits (62), Expect = 0.015 Identities = 36/163 (22%), Positives = 66/163 (40%), Gaps = 35/163 (21%) Query: 14 AMILSNNVFADEGHGIVKFKGEVISAPCSIKPGDEDLTVNLGEVADTVLKSDQKSLAE-- 71 A+++S +V A + + FKG++I C++ ++ VN G++ L + + Sbjct: 15 AVLMSQHVHAADN---LTFKGKLIIPACTV----QNAEVNWGDIEIQNLVQSGGNQKDFT 67 Query: 72 -----PFTIHLQDCMLSQGGTTYSKAKVTFTTANTMTGQSDLLKNTKETEIGGATGVGVR 126 P+++ ++ G T + V T+ + G L N+ + IG A Sbjct: 68 VDMNCPYSLGTMKVTITSNGQTGNSILVPNTSTASGDGLLIYLYNSNNSGIGNA------ 121 Query: 127 ILDSQSGEVTLGTPVV---ITFNNTNS----YQELNFKARMES 162 VTLG+ V IT Y +L +K M+S Sbjct: 122 --------VTLGSQVTPGKITGTAPARKITLYAKLGYKGNMQS 156
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 633 bits (1633), Expect = 0.0 Identities = 222/825 (26%), Positives = 381/825 (46%), Gaps = 56/825 (6%) Query: 16 ASAYAVEFNKDLIEAEDRENVNLSQFETDGQLPVGKYSLSTLINNKRTPIHLDLQWVLID 75 S+ + FN + + + +LS+FE +LP G Y + +NN D+ + D Sbjct: 42 LSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMA-TRDVTFNTGD 100 Query: 76 N--QTAVCVTPEQLTLLGFTDEFIEKTQQNLIDGCYPIEK-EKQITTYLDKGKMQLSISA 132 + C+T QL +G + D C P+ T LD G+ +L+++ Sbjct: 101 SEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLTSMIHDATAQLDVGQQRLNLTI 160 Query: 133 PQAWLKYKDANWTPPELWNHGIAGAFLDYNLYASHYAPHQGDNSQNISSYGQAGVNLGAW 192 PQA++ + + PPELW+ GI L+YN + G NS Q+G+N+GAW Sbjct: 161 PQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNLQSGLNIGAW 220 Query: 193 RLRTDYQYDQSFNNGKS-QATNLDFPRIYLFRPIPAMNAKLTIGQYDTESSIFDSFHFSG 251 RLR + + + ++ S +L R I + ++LT+G T+ IFD +F G Sbjct: 221 RLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGDIFDGINFRG 280 Query: 252 ISLKSDENMLPPDLRGYAPQITGVAQTNAKVTVSQNNRIIYQENVPPGPFAITNLFNT-L 310 L SD+NMLP RG+AP I G+A+ A+VT+ QN IY VPPGPF I +++ Sbjct: 281 AQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGN 340 Query: 311 QGQLDVKVEEEDGRVTQWQVASNSIPYLTRKGQIRYTTAMGKPTSVGGDSLQQPFFWTGE 370 G L V ++E DG + V +S+P L R+G RY+ G+ S G ++P F+ Sbjct: 341 SGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRS-GNAQQEKPRFFQST 399 Query: 371 FSWGWLNNVSLYGGSVLTNRDYQSLAAGVGFNLNSLGSLSFDVTRSDAQLHNQDKETGYS 430 G ++YGG+ L +R Y++ G+G N+ +LG+LS D+T++++ L + + G S Sbjct: 400 LLHGLPAGWTIYGGTQLADR-YRAFNFGIGKNMGALGALSVDMTQANSTLPDDSQHDGQS 458 Query: 431 YRANYSKRFESTGSQLTFAGYRFSDKNFVTMNEYIND--------------------TNH 470 R Y+K +G+ + GYR+S + + T++ Sbjct: 459 VRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDY 518 Query: 471 YTNYQNEKESYIVTFNQYLESLRLNTYVSLARNTYWDAS-SNVNYSLSLSRDFDIGPLKN 529 Y N++ +T Q L Y+S + TYW S + + L+ F ++ Sbjct: 519 YNLAYNKRGKLQLTVTQQLGR-TSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF-----ED 572 Query: 530 VSTSLTFSRIN--WEEDNQDQLYLNISIPWGTSR-----------TLSYGMQRNQDNEIS 576 ++ +L++S W++ L LN++IP+ + SY M + + ++ Sbjct: 573 INWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMT 632 Query: 577 HTASWYDS--SDRNNSWSVSASGDNDEFKDMKASLRASYQHNTENGRLYLSGTSQRDSYY 634 + A Y + D N S+SV + ++ A+ + G + + D Sbjct: 633 NLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDD-IK 691 Query: 635 SLNASWNGSFTATRHGAAFHDYSGSADSRFMIDADGTEDIPLNNKRAV-TNRYGIGVIPS 693 L +G A +G D+ ++ A G +D + N+ V T+ G V+P Sbjct: 692 QLYYGVSGGVLAHANGVTLGQPLN--DTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPY 749 Query: 694 VSSYITTSLSVDTRNLPENVDIENSVITTTLTEGAIGYAKLDTRKGYQIIGVIRLADGSH 753 + Y +++DT L +NVD++N+V T GAI A+ R G +++ + + Sbjct: 750 ATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTLT-HNNKP 808 Query: 754 PPLGISVKDETSHKELGLVADGGFVYLNGIQDDNKLALRWGDKSC 798 P G V E+S + G+VAD G VYL+G+ K+ ++WG++ Sbjct: 809 LPFGAMVTSESS-QSSGIVADNGQVYLSGMPLAGKVQVKWGEEEN 852
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 51.6 bits (123), Expect = 7e-09 Identities = 47/287 (16%), Positives = 92/287 (32%), Gaps = 16/287 (5%) Query: 197 PNNAFDAEGLTKLTQETERRRRERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQ 256 N A+ + + E R A + + ++ E +QE+ + Sbjct: 999 TPNNIQAD-VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVA---ENSKQESKTVEKN 1054 Query: 257 EQQVKTRTAEQNARIAAFEAERRREAE-QTRILAERQIQETEIDREQAVRSRKVEAEREV 315 EQ TA+ R A EA+ +A QT +A+ + E + + VE E + Sbjct: 1055 EQDATETTAQN--REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKA 1112 Query: 316 RIKEIEQQQVTEIANQTKSIAIAAKSEQ---QSQAEARANLALAEAVSAQQNVETTRQTA 372 +++ + Q+V ++ +Q +++ Q + E + + E S T Q A Sbjct: 1113 KVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPA 1172 Query: 373 EADRAKQVALIAAAQDAET------KAVELTVRAKAEKEAAEMQAAAIVELAEATRKKGL 426 + + + + T T +E + R Sbjct: 1173 KETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPH 1232 Query: 427 AEAEAQRALNDAINVLSDEQTSLKFKLALLQALPAVIEKSVEPMKSI 473 A + ND V + TS L A ++ K++ Sbjct: 1233 NVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAV 1279
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 29.0 bits (65), Expect = 0.028 Identities = 10/37 (27%), Positives = 20/37 (54%) Query: 347 GVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRL 383 G FD + GH+ + +L D++ VAV + + + + Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPM 43
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 537 bits (1385), Expect = 0.0 Identities = 173/397 (43%), Positives = 254/397 (63%), Gaps = 11/397 (2%) Query: 11 VLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAFLSVN-GGEPAP--LAHHSYEGA 67 +LVINCGSSS+K+ ++++ D VL G+A+ I ++ L+ N GE ++ A Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHNANGEKIKIKKDMKDHKDA 62 Query: 68 LKAIAFELEKRNLN-----DSVALIGHRIAHGGSIFTESAIITDEVIDNIRRVSPLAPLH 122 +K + L + + +GHR+ HGG FT S +ITD+V+ I LAPLH Sbjct: 63 IKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPLH 122 Query: 123 NYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLPWKYYEELGVRRYGFHGTS 182 N AN+ GI++ Q+ P V VAVFDT+FHQTM AYLY +P++YY + +R+YGFHGTS Sbjct: 123 NPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGTS 182 Query: 183 HRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQSVDTSMGMTPLEGLMMGTRSG 242 H+YVSQRA +LN + ++ HLGNG+SI AV+NG+S+DTSMG TPLEGL MGTRSG Sbjct: 183 HKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRSG 242 Query: 243 DVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLSSDLR-VLEKAWHEGHERAQLAI 301 +D +S++ + N S ++ ++NK+SG+ GISG+SSD R + + A+ G +RAQLA+ Sbjct: 243 SIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKRAQLAL 302 Query: 302 KTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLIRRLVMEHLAVLGLEIDTEMNNRS 361 F +R+ + I +AA++ +D I+FT GIGEN IR +++ L LG ++D E N Sbjct: 303 NVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNKVR 362 Query: 362 NSCGERIVSSENARVICAVIPTNEEKMIALDAIHLGK 398 E I+S+ +++V V+PTNEE MIA D + + Sbjct: 363 GE--EAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.014 Identities = 8/22 (36%), Positives = 13/22 (59%) Query: 4 VLITGATGLVGGHLLRMLINEP 25 L+TGA G +G H+ + L+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 73.4 bits (180), Expect = 2e-15 Identities = 69/313 (22%), Positives = 109/313 (34%), Gaps = 77/313 (24%) Query: 396 IMGHVDHGKTSLLDYI-----RSTKVASGEAG-------------GITQHIGAYHVETEN 437 ++ HVD GKT+L + + T++ S + G GIT G + EN Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 438 GMITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAV 497 + +DTPGH F + R D +L+++A DGV QT + +P + + Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 498 NKIDKPEADPDRV----KNELSQYGI-----------------LPEEWG----------- 525 NKID+ D V K +LS + E+W Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 526 ---------------GESQFV---------HVSAKAGTGIDELLDAILLQAEVLELKAVR 561 ES H SAK GID L++ I + Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 562 KGMASGAVIESFLDKGRGPVATVLVREGTLHKGDIVL-CGFEYGRVRAMRNELGQEVLEA 620 + G V + + R +A + + G LH D V E ++ M + E+ + Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 621 GPSIPVEILGLSG 633 + EI+ L Sbjct: 306 DKAYSGEIVILQN 318
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.5 bits (102), Expect = 2e-06 Identities = 39/199 (19%), Positives = 70/199 (35%), Gaps = 19/199 (9%) Query: 143 DLAGNATDQANGVQPAPGTTSAENTQQDVSL-----------------PPISSTPTQGQT 185 DL ++ N T+ N Q DV PP +TP++ Sbjct: 979 DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038 Query: 186 PVATDGQQRVEVQGDLNNALTQPQNQQQLNNVAVNSTLPTEPATVAPVRNGNASRDTAKT 245 VA + +Q + T+ Q + S + T ++G+ +++T T Sbjct: 1039 TVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 246 QTAERPSTTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAATSTPA 305 +T E + + + + E + V ++ P + + +P A A P Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 306 PKETATTAPVQTASPAQTT 324 +T TTA T PA+ T Sbjct: 1159 QSQTNTTA--DTEQPAKET 1175 Score = 42.0 bits (98), Expect = 4e-06 Identities = 41/203 (20%), Positives = 68/203 (33%), Gaps = 10/203 (4%) Query: 126 APSTTSSDQTASGEKSIDLAGNATDQANGVQPAPGTTSAENTQQDVSLPPISST-PTQGQ 184 P+ +D + + ++A D+A PAP T S + S T Q Sbjct: 999 TPNNIQADVPSVPSNNEEIA--RVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 185 TPVATDGQQRVEVQGDLNNALTQPQN----QQQLNNVAVNSTLPTEPATVAPVRNGNASR 240 T Q R + +N Q Q +T E ATV + A Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVE--KEEKAKV 1114 Query: 241 DTAKTQTAERPSTTRPARQQAVIEPKKPQATVKTEPKPVAQTPKRTEPAAPVASTKAPAA 300 +T KTQ + ++ +Q+ E +PQA E P + A T+ PA Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQS-ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 301 TSTPAPKETATTAPVQTASPAQT 323 ++ ++ T + + Sbjct: 1174 ETSSNVEQPVTESTTVNTGNSVV 1196
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 32.1 bits (73), Expect = 8e-04 Identities = 27/91 (29%), Positives = 40/91 (43%), Gaps = 18/91 (19%) Query: 32 FYDSDQEIEKRTGADVGWVFDLEGEEGFRD----------REEKVINELTEKQGIVLATG 81 FYD + KR + GW+ + G+R E + I +L E+ IV+A+G Sbjct: 136 FYDEETA--KRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEAETIKKLVERGVIVIASG 193 Query: 82 GGSVKSRETRNRLSARGVVVYLETTIEKQLA 112 GG V + +GV E I+K LA Sbjct: 194 GGGVPVILEDGEI--KGV----EAVIDKDLA 218
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 287 bits (736), Expect = 1e-93 Identities = 80/301 (26%), Positives = 132/301 (43%), Gaps = 18/301 (5%) Query: 117 LENRSITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDNKTALSALEQWVAQMDL 176 L + +I D + +A SA+ + D N +++RD+ + ++ + +D Sbjct: 219 LSDATIQQVTVDNQRIPQAAT-RASAQARVEADPSLNAIIVRDSPERMPMYQRLIHALDK 277 Query: 177 PVGQVELSAHIVTINEKSLRELGVKWTLADAQHAGGVGQVTTLGSDLSVATATTHVGFNI 236 P ++E++ IV IN L ELGV W + + T G ++A+ G Sbjct: 278 PSARIEVALSIVDINADQLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASN----GALG 333 Query: 237 GRINGRLLDL---ELSALEQKQQLDIIASPRLLASHLQPASIKQGSEIPYQVSSGESGAT 293 ++ R LD ++ LE + +++ P LL A I SE Y +G+ A Sbjct: 334 SLVDARGLDYLLARVNLLENEGSAQVVSRPTLLTQENAQAVIDH-SETYYVKVTGKEVA- 391 Query: 294 SVEFKEAVLG--MEVTPTVLQKG---RIRLKLHISQNVPGQVLQQADGEVLAIDKQEIET 348 E K G + +TP VL +G I L LHI +G + I + ++T Sbjct: 392 --ELKGITYGTMLRMTPRVLTQGDKSEISLNLHIEDGNQKPNSSGIEG-IPTISRTVVDT 448 Query: 349 QVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDGKEDERRELVVFITPRL 408 V G++L +GGI+ + VPLLGDIP+ G LFR + R + I PR+ Sbjct: 449 VARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPYIGALFRRKSELTRRTVRLFIIEPRI 508 Query: 409 V 409 + Sbjct: 509 I 509 Score = 37.2 bits (86), Expect = 1e-04 Identities = 28/139 (20%), Positives = 51/139 (36%), Gaps = 24/139 (17%) Query: 1 MKQWIAALLLMLIPGVQAA----KPQKVTLMVDDVPVAQVLQALAEQEKLNLVVSPDVSG 56 K+ + LL+L A P + + +L +VVS ++ Sbjct: 9 FKRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKIND 68 Query: 57 TVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNNNIARQEAEQARAQANLP 116 VS + LQ + L+ +GN+L + ++N+ +A Sbjct: 69 KVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYI----FKNSEVA-------------- 110 Query: 117 LENRSITLQYADAGELAKA 135 +R I LQ ++A EL +A Sbjct: 111 --SRLIRLQESEAAELKQA 127
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 4e-06 Identities = 21/92 (22%), Positives = 34/92 (36%), Gaps = 16/92 (17%) Query: 55 VACIDGDVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMREMIE------MCD 108 + ++ + +G + I + + D + D R K GV +AL+ + IE C Sbjct: 69 LYYLENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKK--GVGTALLHKAIEWAKENHFCG 125 Query: 109 NWLRVDRIELTVFVDNAPAIKVYKKYGFEIEG 140 L I N A Y K+ F I Sbjct: 126 LMLETQDI-------NISACHFYAKHHFIIGA 150
>NAFLGMOTY#Sodium-type flagellar protein MotY precursor signature. Length = 293 Score = 31.6 bits (71), Expect = 0.007 Identities = 27/82 (32%), Positives = 37/82 (45%), Gaps = 17/82 (20%) Query: 275 RTPISGDYRGYQVYSMPPPSSGGIHIVQILNI--LENFDMKKYGF-GSADAMQIMAEAEK 331 R P+ G+ R + SMPPP G H +I N+ + FD G+ G A I++E EK Sbjct: 77 RRPM-GETRNVSLISMPPPWRPGEHADRITNLKFFKQFD----GYVGGQTAWGILSELEK 131 Query: 332 YAYADRSEYLGDPDFVKVPWQA 353 Y P F WQ+ Sbjct: 132 GRY---------PTFSYQDWQS 144
>PF04619#Dr-family adhesin Length = 160 Score = 29.5 bits (66), Expect = 0.008 Identities = 12/65 (18%), Positives = 23/65 (35%), Gaps = 4/65 (6%) Query: 29 VGAKYGHKMIEFDAKLSKDGEIFLLHDDNLERTSNGWGVAGELNWQD----LLRVDAGSW 84 +G ++ D + G+ FL+ D+N ++ W + D GSW Sbjct: 70 LGCDARQVALKADTDNFEQGKFFLISDNNRDKLYVNIRPTDNSAWTTDNGVFYKNDVGSW 129 Query: 85 YSKMF 89 + Sbjct: 130 GGIIG 134
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.003 Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 7/43 (16%) Query: 33 IVMVGPSGCGKSTLLRMVAGLERVTEGDIWINDQRVTEMEPKD 75 +V+ G G GKSTL+ + GL+ + +D KD Sbjct: 599 VVLEGTGGIGKSTLINTLVGLD-------FFSDTHFDIGTGKD 634
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 39.3 bits (91), Expect = 2e-05 Identities = 39/160 (24%), Positives = 66/160 (41%), Gaps = 14/160 (8%) Query: 134 GHLLSQPFNSSTPVLYYNKDAFKKAGLDPEQPPKTWQDLADYAAKLKASGMKCGYASGWQ 193 G L++ P L YNKD PPKTW+++ +LKA G + + Sbjct: 127 GKLIAYPIAVEALSLIYNKDLLP-------NPPKTWEEIPALDKELKAKGKSALMFNLQE 179 Query: 194 GWIQLENFSAWNGLPFASKNNGFDGTDAVLEF--NKPEQVKHIAMLEEMNKKGDFSYVGR 251 + +A G F +N +D D ++ K + +++ + D Y Sbjct: 180 PYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDY--- 236 Query: 252 KDESTEKFYNGDCAMTTASSGSLANIREYAKFNYGVGMMP 291 + F G+ AMT + +NI + +K NYGV ++P Sbjct: 237 -SIAEAAFNKGETAMTINGPWAWSNI-DTSKVNYGVTVLP 274
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 53.5 bits (128), Expect = 1e-09 Identities = 39/181 (21%), Positives = 62/181 (34%), Gaps = 14/181 (7%) Query: 19 EQTPEKETEVQNEQPVVEEI---VQAQEPVKASEQAVEEQPQAHTEAEAETFAADVVEVT 75 TP + TE E E Q+ + + Q E +A + +A T EV Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTN---EVA 1086 Query: 76 EQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEAETV 135 + +E+++ Q E E E +E E+ V ++ VSP++ Q+E Sbjct: 1087 QSGSETKETQTT----ETKETATVEKEEKAKVETEKTQEVPKVTSQ-VSPKQEQSETVQP 1141 Query: 136 EIVEAAEEEA---AKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPTK 192 + A E + KE + A E + V P E V E P Sbjct: 1142 QAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPEN 1201 Query: 193 E 193 Sbjct: 1202 T 1202 Score = 45.4 bits (107), Expect = 4e-07 Identities = 29/157 (18%), Positives = 53/157 (33%), Gaps = 10/157 (6%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASE------QAVEEQPQAHTEAEAETFAAD 70 Q +T E T + E+ VE + P S+ Q+ QPQA E + Sbjct: 1096 QTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 71 VVEVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQA 130 ++ ++ QP E + E V E+ V + PE+ P Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNVEQPVTES-TTVNTGNSVVENPENTTPATTQP---TV 1211 Query: 131 EAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEA 167 +E+ + + + + E T + + + A Sbjct: 1212 NSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248 Score = 41.2 bits (96), Expect = 1e-05 Identities = 31/153 (20%), Positives = 57/153 (37%), Gaps = 7/153 (4%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVE-EQPQAHTEAEAETFAADVV--- 72 + ++ P+ ++V +Q E + EP + ++ V ++PQ+ T A+T Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSS 1177 Query: 73 EVTEQVAESEKAQPEAEVVAQPEPVVEETPEPVAIEREELPLPEDVNAEAVSPEEWQAEA 132 V + V ES VV PE T +P E P++ + +V E Sbjct: 1178 NVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS-ESSNKPKNRHRRSVRSVPHNVEP 1236 Query: 133 ETVEIVEAAEEEAAKEEITDEELETALAAEAAE 165 T + A ++T L+ A+ Sbjct: 1237 ATTSSNDR--STVALCDLTSTNTNAVLSDARAK 1267 Score = 38.1 bits (88), Expect = 9e-05 Identities = 29/178 (16%), Positives = 53/178 (29%), Gaps = 7/178 (3%) Query: 17 QKEQTPEKETEVQNEQPVVEEIVQAQEPVKASEQAVEEQPQAHTEAE-AETFAADVVEVT 75 +E E ++ V+ E+ Q+ K ++ ++ + E A+ EV Sbjct: 1065 NREVAKEAKSNVKAN-TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 76 EQVAESEKAQPEAEVV-AQPEPVVEETPEPVAIEREELPLPEDVNAEAVSP-EEWQAEAE 133 + ++ Q ++E V Q EP E P E + + A+ P +E + E Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQS---QTNTTADTEQPAKETSSNVE 1180 Query: 134 TVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVMVVPPAEEEQPVEEIAQEQEKPT 191 E A P + V + E T Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPAT 1238 Score = 34.3 bits (78), Expect = 0.001 Identities = 30/144 (20%), Positives = 50/144 (34%), Gaps = 9/144 (6%) Query: 52 VEEQPQAHTEAEAETFAADVVEVT-EQVAESEKAQPEAEVVAQPEPVVE-ETPEPVAIER 109 VE++ Q T +V E A+ + V P P ET E VA Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 110 EELPLPEDVNAEAVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELETALAAEAAEEAVM 169 ++ ++ V E A T + E A+E + + + E A + +E Sbjct: 1045 KQ-------ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 170 VVPPAEEEQPVEEIAQEQEKPTKE 193 EE A+ + + T+E Sbjct: 1098 TETKETATVEKEEKAKVETEKTQE 1121
>SHIGARICIN#Ribosome inactivating protein family signature. Length = 289 Score = 25.9 bits (57), Expect = 0.042 Identities = 6/21 (28%), Positives = 13/21 (61%) Query: 7 FFIVIIGLIVVAASFRFMQQR 27 +V+I AA ++F++Q+ Sbjct: 173 ALMVLIQSTSEAARYKFIEQQ 193
>PF01206#SirA family protein Length = 76 Score = 105 bits (265), Expect = 3e-34 Identities = 24/72 (33%), Positives = 41/72 (56%) Query: 9 DHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIADDPATTRDIPGFCTFMEHELVAKET 68 D +LDA GL CP P++ +KT+ M GE L ++A DP + +D F HEL+ ++ Sbjct: 5 DQSLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKE 64 Query: 69 DGLPYRYLIRKG 80 + Y + +++ Sbjct: 65 EDGTYHFRLKRA 76
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.8 bits (132), Expect = 2e-10 Identities = 80/398 (20%), Positives = 147/398 (36%), Gaps = 32/398 (8%) Query: 13 LRLNLRIVSIVMFNFASYLTIGLPLAVLPGYVHDVM--GFSAFWAGLVISLQYFATLLSR 70 ++ N ++ I+ + IGL + VLPG + D++ G++++L Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 71 PHAGRYADSLGPKKIVVFGLCGCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGI-GQS 129 P G +D G + +++ L G + + Y L V L +GR++ GI G + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWV-----LYIGRIVAGITGAT 112 Query: 130 FAGTGSTLWGVGVVGSL--HIGRVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIM 187 A G+ + + H G + + G +G +G H A AL + Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL 172 Query: 188 GVALVAILLAIPRPTVK--ASKGKPLPFRAVLGRVWLYGMALALA-----SAGFGVIATF 240 LL + + P + + +A +A V A Sbjct: 173 NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAAL 232 Query: 241 ITLFYDAK-GWDGAAFALTLFSCAFVGT---RLLFPNGINRIGGLNVAMICFSVEIIGLL 296 +F + + WD ++L + + + ++ R+G M+ + G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 297 LVGVATMPWMAKIG-VLLAGAGFSLVFPALGVVAVKAVPQQNQGAALATYTVFMDLSLGV 355 L+ AT WMA VLLA G + PAL + + V ++ QG + L+ + Sbjct: 293 LLAFATRGWMAFPIMVLLASGGIGM--PALQAMLSRQVDEERQGQLQGSLAALTSLT-SI 349 Query: 356 TGPLAGLVMSWAGVPV----IYLAAAGLVAIALLLTWR 389 GPL + A + ++A A L + L R Sbjct: 350 VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.020 Identities = 10/34 (29%), Positives = 19/34 (55%) Query: 25 QAVLNNVSLTLKSGETVALLGRSGCGKSTLARLL 58 Q + ++ +++ T+ + G SG GK +AR L Sbjct: 147 QEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 49.9 bits (119), Expect = 5e-09 Identities = 41/171 (23%), Positives = 73/171 (42%), Gaps = 7/171 (4%) Query: 200 REREHGTVEHLLVMPITPFEIMMAKI-WSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPL 258 R T E +L + +I++ ++ W+ L +G+ +V G + L Sbjct: 93 RMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY----TQWLSLL 148 Query: 259 FMLGV-ALSLFATTSIGIFMGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQD 317 + L V AL+ A S+G+ + +A S LV+ P+ LSG P + +P + Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 318 IMLTMPTTHFVSLAQAILYRGAGFEIVWPQFLTLMAIGGAFF-TIALLRFR 367 +P +H + L + I+ ++ + I FF + ALLR R Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.045 Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 37 ARCMVGLIGPDGVGKSSLLSLISGAR 62 V L G G+GKS+L++ + G Sbjct: 595 FDYSVVLEGTGGIGKSTLINTLVGLD 620
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 65.2 bits (159), Expect = 8e-19 Identities = 17/50 (34%), Positives = 32/50 (64%) Query: 1 MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQESYELAAFLACKLKE 50 +P+ + ++++C TLL FT++ R SLCE+ + E+AAF+A + + Sbjct: 3 LPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYESGK 52
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 27.5 bits (61), Expect = 0.017 Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 77 MTCLTVFIISVALLMVGLWNATLLLSEKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKET 136 MT T II LL L + + GLA FL+ F V I P E Sbjct: 61 MTSFTRIIIVFGLLRNALGTPSAP-PNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEE 119 Query: 137 QVTQEE 142 +++ +E Sbjct: 120 KISMQE 125
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 102 bits (256), Expect = 3e-27 Identities = 76/348 (21%), Positives = 127/348 (36%), Gaps = 67/348 (19%) Query: 2 IIVTGGAGFIGSNIVKALNDKGITDILVVDNLKD--------------GTKFVNLVDLNI 47 +VTG AGFIG ++ K L + G ++ +DNL D +++ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 48 ADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSK-------EL 100 AD + + + A F E +F + +Y ++N + Y+ + Sbjct: 62 ADR----EGMTDLFASGHF---ERVFISPHRLAV-----RYSLENPHAYADSNLTGFLNI 109 Query: 101 LHYCLEREIP-FLYASSAATYGGRTSD-FIESREYEKPLNVYGYSKFLFDEYVRQILPEA 158 L C +I LYASS++ YG F + P+++Y +K + Sbjct: 110 LEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 159 NSQIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA 218 G R+F VYGP + MA F + G+S ++ KRDF Y+ D+A Sbjct: 170 GLPATGLRFFTVYGPWG--RPDMA--LFKFTKAMLEGKSIDVY-NYGKMKRDFTYIDDIA 224 Query: 219 DVNL------------WFLENGVSG-------IFNLGTGRAESFQAVADATLAY-HKKGQ 258 + + W +E G ++N+G A + + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAK 284 Query: 259 IEYIPFPDKLKGRYQAFTQADLTNLRAA-GYDKPFKTVAEGVTEYMAW 305 +P G T AD L G+ P TV +GV ++ W Sbjct: 285 KNMLPLQ---PGDVL-ETSADTKALYEVIGF-TPETTVKDGVKNFVNW 327
>SECA#SecA protein signature. Length = 901 Score = 41.8 bits (98), Expect = 1e-05 Identities = 38/129 (29%), Positives = 56/129 (43%), Gaps = 18/129 (13%) Query: 233 NLSMLALRAGAQRFHAQPLSANDTLKNKLLAALPFKPTGAQARVVAEIERDM-ALDVPMM 291 LS L+ F A+ L + L+N + A A R ++ M DV ++ Sbjct: 37 KLSDEELKGKTAEFRAR-LEKGEVLENLIPEAF------AVVREASKRVFGMRHFDVQLL 89 Query: 292 ---RLVQGDV-----GSGKTLVAALAA-LRAIAHGKQVALMAPTELLAEQHANNFRNWFA 342 L + + G GKTL A L A L A+ GK V ++ + LA++ A N R F Sbjct: 90 GGMVLNERCIAEMRTGEGKTLTATLPAYLNALT-GKGVHVVTVNDYLAQRDAENNRPLFE 148 Query: 343 PLGIEVGWL 351 LG+ VG Sbjct: 149 FLGLTVGIN 157
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 71/391 (18%), Positives = 129/391 (32%), Gaps = 33/391 (8%) Query: 20 LLVAFLTGIAGALQTPTLSIFLADELKARPIM--VGFFFTGSAIMGILVSQFLARHSDKQ 77 L L + L P L L D + + + G A+M + L SD+ Sbjct: 11 LSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRF 70 Query: 78 GDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFASTANPQMFALAREHADRTG 137 G R ++L+ + + A ++L ++ A AD T Sbjct: 71 GRR-PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV----AGITGATGAVAGAYIADITD 125 Query: 138 RET-VMFSTFLRAQISLAWVIGPPLAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLP-- 194 + F+ A V GP L + GFS + AA + L LP Sbjct: 126 GDERARHFGFMSACFGFGMVAGPVLGGLMG-GFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 195 --SIQRNIPVVT-QPVEILPSTHRKRDTRLLFVVCSMMWAANNLYMINMPLFIIDELHLT 251 +R + P+ L V +M + +F D H Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 252 DKLTGEMI-GIAAGLEIPMMLIAGYYMKRIGKRLLMLIAIVSGMCFYASVLMATTPAVEL 310 G + + +I G R+G+R +++ +++ Y +L+A + Sbjct: 245 ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGY--ILLAFATRGWM 302 Query: 311 ELQILNAIFLGILCGIGMLYFQDLMPEKI---------GSATTLYANTSRVGWIIAGSVD 361 + L GIGM Q ++ ++ GS L + TS VG ++ ++ Sbjct: 303 ---AFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Query: 362 GIMVEIWSYHALFWLAIGMLGIAMICLLFIK 392 + W+ W I + ++CL ++ Sbjct: 360 AASITTWNG----WAWIAGAALYLLCLPALR 386 Score = 32.1 bits (73), Expect = 0.004 Identities = 18/102 (17%), Positives = 34/102 (33%) Query: 17 AAFLLVAFLTGIAGALQTPTLSIFLADELKARPIMVGFFFTGSAIMGILVSQFLARHSDK 76 AA + V F+ + G + IF D +G I+ L + Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 77 QGDRKLLILLCCLFGVLACTLFAWNRNYFILLSTGVLLSSFA 118 + + ++L + L A+ ++ VLL+S Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGG 314
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 35/208 (16%), Positives = 71/208 (34%), Gaps = 13/208 (6%) Query: 88 IIVEFLPVSLLTP----MAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDR--RY 141 + ++ + + L+ P + +DL S V + A A+ +DR R Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRR 73 Query: 142 VVILFAVLL-TLSCLLVSFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKA 200 V+L ++ + +++ A +L IGR G+ G A++ + + + Sbjct: 74 PVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARH 132 Query: 201 LSVIFGAVSIALVIAAPLGSFLGELIGWRNVFNAAAVMG----VLCIFWIIKSLPSLPGE 256 + +V LG +G F AAA + + F + +S Sbjct: 133 FGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 257 PSHQKQNTFRLLQRPGVMAGMIAIFMSF 284 + N + M + A+ F Sbjct: 192 LRREALNPLASFRWARGMTVVAALMAVF 219
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 38.2 bits (89), Expect = 9e-05 Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 17/105 (16%) Query: 22 AVSRGDAVADYIIDNVSILDLINGGEISGPIVIKGRYIAGVG----------AEYTDAPA 71 V+R D +I N ILD + G + I +K IA +G P Sbjct: 60 QVTREGGAVDTVITNALILD--HWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPG 117 Query: 72 LQRIDARGATAVPGFIDAHLHIESSMMTPVTFETATLPRGLTTVI 116 + I G G +D+H+H + P E A L GLT ++ Sbjct: 118 TEVIAGEGKIVTAGGMDSHIH----FICPQQIEEA-LMSGLTCML 157
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.1 bits (78), Expect = 0.001 Identities = 28/168 (16%), Positives = 61/168 (36%), Gaps = 17/168 (10%) Query: 49 FNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFMLILSAIC 108 N++ D+ + + + F +T+ +G + +D K+ L F +I++ C Sbjct: 33 LNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIIN--C 90 Query: 109 MLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTI----TKWTPRRKRGTFLGFW 164 +G SL +M + F Q G + + + ++ P+ RG G Sbjct: 91 FGSVIGFVGHSFFSLLIM------ARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 165 NISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRY 212 +G + A+Y+ + + + P + I+ L Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWSY---LLLIP--MITIITVPFLMK 187
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.6 bits (95), Expect = 9e-06 Identities = 65/408 (15%), Positives = 137/408 (33%), Gaps = 60/408 (14%) Query: 29 RHILLTIWLGYALFY--FTRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSG 86 RH + IWL F+ N ++P+I + + + T F +T+ + V G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 IVSDRSNARYFMGIGLIATGIINILFGFSTSLWAFAVLWVLNAFFQGWGS---PVCARLL 143 +SD+ + + G+I +++ S F L ++ F QG G+ P ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHS---FFSLLIMARFIQGAGAAAFPALVMVV 127 Query: 144 TAWY-SRTERGGWWALWNTAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLC 202 A Y + RG + L + +G + P + A + W ++ M ++ + Sbjct: 128 VARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW--SYLLLIPMITIITVPF- 184 Query: 203 WRLRDRPQALGLPAVGEWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLV 262 + L +I G L I+ + Y VL Sbjct: 185 --------LMKLLKKEVRIKGHFDIK----GIILMSVGIVFFMLFTTSYSISFLIVSVLS 232 Query: 263 YVV-----RAAINDWGNLYMSETLGVDLVTANTAVTMFELGGFI-----------GALVA 306 +++ R + + + + + + + + + GF+ A Sbjct: 233 FLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 307 GWGSDKLFNGNRGPMNLIFAAGILL-SVGSLWLMPFASYVMQATCFFTIGFFVFGPQMLI 365 GS +F G + + GIL+ G L+++ + + F T F + + Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFL-SVSFLTASFLLETTSWFM 351 Query: 366 ---------GMAAAECS---------HKEAAGAATGFVGLFAYLGASL 395 G++ + ++ AGA + ++L Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>PF06580#Sensor histidine kinase Length = 349 Score = 39.8 bits (93), Expect = 2e-05 Identities = 28/142 (19%), Positives = 56/142 (39%), Gaps = 11/142 (7%) Query: 365 LRPRQLDDLTLEQAIRSLMREMELEGRGIVSHLEWRIDESALSENQRVTLFRVCQEGLNN 424 LR ++L + + ++L L++ + + +V + Q + N Sbjct: 208 LRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPM-LVQTLVEN 266 Query: 425 IVKHA-----DASAVTLQGWQQDERLMLVIEDDGSGLPPGSGQ-QGFGLTGMRERVTALG 478 +KH + L+G + + + L +E+ GS + + G GL +RER+ L Sbjct: 267 GIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY 326 Query: 479 G---TLHISCLHG-TRVSVSLP 496 G + +S G V +P Sbjct: 327 GTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 2e-13 Identities = 29/174 (16%), Positives = 59/174 (33%), Gaps = 20/174 (11%) Query: 2 ITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDIS 61 T+ + DD +R+ Q L V + + + + D+ MPD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLELLSQLPK---GMATIMLSVHDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATG 118 +LL ++ K + +++S ++ +A GA +L K ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR---- 117 Query: 119 GCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQG---MAVKEIAAELGLSPKTV 169 A+ R L + + + + + A L + T+ Sbjct: 118 --------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL 163
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.048 Identities = 23/80 (28%), Positives = 31/80 (38%), Gaps = 10/80 (12%) Query: 367 LGDAEIGDNVNIGAGTITCNYDGANKFKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTT 426 LGD + D V + AG+ N G DV T G AT A T Sbjct: 616 LGDGD--DKVFLSAGSA--NIYAGK------GHDVVYYDKTDTGYLTIDGTKATEAGNYT 665 Query: 427 VTRNVGENALAISRVPQTQK 446 VTR +G + + V + Q+ Sbjct: 666 VTRVLGGDVKVLQEVVKEQE 685
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 27.3 bits (60), Expect = 0.028 Identities = 20/101 (19%), Positives = 37/101 (36%), Gaps = 18/101 (17%) Query: 31 AAIEKRQKEIADGLASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQ--ANKRRSQILD 88 +EK +++ + A K+ + T + A++ ++ Q K + + Sbjct: 1049 KTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEK 1108 Query: 89 EAKAEAEQERTKIVA----------------QAQAEIEAER 113 E KA+ E E+T+ V Q QAE E Sbjct: 1109 EEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN 1149
>SECA#SecA protein signature. Length = 901 Score = 30.2 bits (68), Expect = 0.004 Identities = 11/71 (15%), Positives = 30/71 (42%) Query: 14 AKARRKTREELDQEARDRKRQKKRRGHAPGSRAAGGNTTSGSKGQNAPKDPRIGSKTPIP 73 +K + + EE+++ + R+ + +R ++ + + + ++G P P Sbjct: 827 SKVQVRMPEEVEELEQQRRMEAERLAQMQQLSHQDDDSAAAAALAAQTGERKVGRNDPCP 886 Query: 74 LGVTEKVTKQH 84 G +K + H Sbjct: 887 CGSGKKYKQCH 897
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 602 bits (1553), Expect = 0.0 Identities = 206/478 (43%), Positives = 300/478 (62%), Gaps = 11/478 (2%) Query: 1 MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALASKTPDVLLSDIRMPGM 60 M + V DDD++IR VL +AL+ AG N A + +A+ D++++D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYLPKPFDIDEAVALVERAIS 120 + LL +IK+ P LPV++M+A + A+ A ++GA+DYLPKPFD+ E + ++ RA++ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 HYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRSSISVLINGESGTGKELVAHA 180 + + ++G + AMQ+++R++ RL ++ ++++I GESGTGKELVA A Sbjct: 121 EPKRRPSKLEDDSQDGM-PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 181 LHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFTGANTIRQGRFEQADGGTLFLDE 240 LH + R PF+A+NMAAIP+DLIESELFGHEKGAFTGA T GRFEQA+GGTLFLDE Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 241 IGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRIIAATHQNLEQRVQEGKFREDLFHR 300 IGDMP+D QTRLLRVL G++ VGG P++ DVRI+AAT+++L+Q + +G FREDL++R Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 301 LNVIRVHLPPLRERREDIPRLARHFLQVAARELGVEAKLLHPETEAALTRLAWPGNVRQL 360 LNV+ + LPPLR+R EDIP L RHF+Q A +E G++ K E + WPGNVR+L Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVREL 358 Query: 361 ENTCRWLTVMAAGQEVLIQDLPGELFESTVAESTSQMQPDSWATLLAQWADRALRS---- 416 EN R LT + + + + EL + S + ++Q + +R Sbjct: 359 ENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFAS 418 Query: 417 -----GHQNLLSEAQPELERTLLTTALRHTQGHKQEAARLLGWGRNTLTRKLKELGME 469 L E+E L+ AL T+G++ +AA LLG RNTL +K++ELG+ Sbjct: 419 FGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>PF06580#Sensor histidine kinase Length = 349 Score = 28.3 bits (63), Expect = 0.042 Identities = 34/190 (17%), Positives = 72/190 (37%), Gaps = 41/190 (21%) Query: 171 IIEQADRLRNLVDRL---LGPQLPGTRVTE-SIHKVAERV---VTLVSMELPDNVRLIRD 223 I+E + R ++ L + L + + S+ V + L S++ D ++ Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 224 YDPSLPELAHDPDQIEQVLLN-IVRNALQ---ALGPEGGEIILRTRTAFQLTLHGERYRL 279 +P++ ++ Q+ +L+ +V N ++ A P+GG+I+L+ Sbjct: 246 INPAIMDV-----QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGT------KDNGTVT- 293 Query: 280 AARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGK---IEFTSWP 336 ++VE+ G + ++ TG GL R + G I+ + Sbjct: 294 ---LEVENTGSLALKNTKE------------STGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 337 GHTEFSVYLP 346 G V +P Sbjct: 339 GKVNAMVLIP 348
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 180 bits (458), Expect = 4e-51 Identities = 97/445 (21%), Positives = 170/445 (38%), Gaps = 81/445 (18%) Query: 4 KLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQE--RVMDSNDLEKERGITILAKNT 61 K+ NI ++AHVD GKTTL + LL SG + D+ LE++RGITI T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 62 AIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAFDGPMPQTRFVTKKAFAYGL 121 + +W + ++NI+DTPGH DF EV R +S++D +L++ A DG QTR + G+ Sbjct: 62 SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121 Query: 122 KPIVVINKVDRPGARPDWVVDQVFD-------------LFVNLDATDEQLD--------- 159 I INK+D+ G V + + L+ N+ T+ Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181 Query: 160 --------------------------------FPIVYASALNGIAGLDHEDMAEDMTPLY 187 FP+ + SA N I G+D+ L Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNI-GIDN---------LI 231 Query: 188 QAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGVIGIGRIKRGKVKPNQQVTIIDSEGKTR 247 + I + + ++ +++Y+ + R+ G + V I + E Sbjct: 232 EVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI-- 289 Query: 248 NAKVGKVLGHLGLERIETDLAEAGDIVAITGLGELNISDTVCDTQNVEALPALSVDEPTV 307 K+ ++ + E + D A +G+IV + L ++ + DT+ + + P + Sbjct: 290 --KITEMYTSINGELCKIDKAYSGEIVILQNEF-LKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 308 SMFFCVNTSPFCGKEGKFVTSRQILDRLNKELVHNVALRVEETEDADAFRVSGRGELHLS 367 + + D L LR +S G++ + Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQME 397 Query: 368 VLIENMRRE-GFELAVSRPKVIFRE 391 V ++ + E+ + P VI+ E Sbjct: 398 VTCALLQEKYHVEIEIKEPTVIYME 422 Score = 32.5 bits (74), Expect = 0.005 Identities = 13/75 (17%), Positives = 29/75 (38%), Gaps = 1/75 (1%) Query: 398 EPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIGFRSEFMT 457 EPY + + +++ + ++ + V L IP+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 458 MTSGTGLLYSTFSHY 472 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGY 610
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.028 Identities = 31/161 (19%), Positives = 64/161 (39%), Gaps = 15/161 (9%) Query: 227 NVFFVYAVYCGLTFFIPFLKNIYLLP----------VALVGAYGIINQYCLKMIGGPIGG 276 N+ F+ V CG F + ++P A +G+ I +I G IGG Sbjct: 255 NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGG 314 Query: 277 MISDKILKSPSKYLCYTFIISTAALVLLIMLPHESMPVYLGMACTLGFGAIVFTQRAVFF 336 ++ D+ + P L + + + L E+ ++ + G + FT+ Sbjct: 315 ILVDR--RGPLYVLNIGVTFLSVSFLTASFLL-ETTSWFMTIIIVFVLGGLSFTK--TVI 369 Query: 337 APIGEAKIAENKTGAAMALGSFIGYAPAMFCFSLYGYILDL 377 + I + + + + GA M+L +F + ++ G +L + Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 6e-06 Identities = 31/155 (20%), Positives = 64/155 (41%), Gaps = 5/155 (3%) Query: 114 LTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQQLAEQQRLAQQSR 173 + +QAD+ P+ E+ ++ P + +AE + Q+S+ Sbjct: 992 VDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK--QESK 1049 Query: 174 TTEQSWQQQT-RTSQAAPVQAQPRQSKPASSQQPYQDLLQTPAHTTAQSKPQQAAPVARA 232 T E++ Q T T+Q V + + + A++Q + T ++ ++ A V + Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 233 ADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQ 267 A T + ++ + Q + EQ+ETV+ Q Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSPKQ--EQSETVQPQ 1142
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 756 bits (1953), Expect = 0.0 Identities = 396/396 (100%), Positives = 396/396 (100%) Query: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK Sbjct: 1 MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYNGLAEVGKKFEKDTGIK 60 Query: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQDKLYPFTW 120 Query: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP Sbjct: 121 DAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALDKELKAKGKSALMFNLQEP 180 Query: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE Sbjct: 181 YFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIAE 240 Query: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE Sbjct: 241 AAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASPNKE 300 Query: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP Sbjct: 301 LAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIP 360 Query: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK Sbjct: 361 QMSAFWYAVRTAVINAASGRQTVDEALKDAQTRITK 396
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.7 bits (79), Expect = 6e-04 Identities = 13/35 (37%), Positives = 18/35 (51%) Query: 32 VVFVGPSGCGKSTLLRMIAGLETITSGDLFIGEKR 66 VV G G GKSTL+ + GL+ + IG + Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>PERTACTIN#Pertactin signature. Length = 922 Score = 27.0 bits (59), Expect = 0.048 Identities = 15/50 (30%), Positives = 19/50 (38%), Gaps = 4/50 (8%) Query: 119 GGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSG----GAQSRPQQSAPAAP 164 G APAGG + GG GG + + G + QS AP Sbjct: 261 GDAPAGGAVPGGAVPGGAVPGGFGPLLDGWYGVDVSDSTVDLAQSIVEAP 310
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.020 Identities = 5/33 (15%), Positives = 13/33 (39%), Gaps = 1/33 (3%) Query: 17 ELVEKR-QRFATILSIIMLAVYIGFILLIAFAP 48 EL+E R +++ ++ + +L Sbjct: 47 ELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQ 79
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 29.9 bits (67), Expect = 0.006 Identities = 6/21 (28%), Positives = 11/21 (52%) Query: 179 FGNLDDPNSEISQLLRQKPTY 199 GNL++P ++ L+ P Sbjct: 75 TGNLEEPAVMVNYFLQGDPYQ 95
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 3e-04 Identities = 20/84 (23%), Positives = 32/84 (38%), Gaps = 5/84 (5%) Query: 50 HLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNVGSKLLAWAEEEARQAG 109 L L+ +G I + + N I+++ V R VG+ LL A E A++ Sbjct: 68 FLYYLENNCIGRIKIRSNW-----NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122 Query: 110 AEMTELSTNVKRHDAHRFYLREGY 133 L T A FY + + Sbjct: 123 FCGLMLETQDINISACHFYAKHHF 146
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.013 Identities = 17/70 (24%), Positives = 25/70 (35%), Gaps = 8/70 (11%) Query: 36 CVVLHGHSGSGKSTLLRSLYANYLPDEGQIQIKHGDEWVDLVTAPARKVVEI------RK 89 VVL G G GKSTL+ +L + I G + + + E+ R+ Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQIAGIV--AYELSEMTAFRR 655 Query: 90 TTVGWVSQFL 99 V F Sbjct: 656 ADAEAVKAFF 665
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 7e-06 Identities = 21/99 (21%), Positives = 38/99 (38%), Gaps = 18/99 (18%) Query: 442 LIENALE-ALGP-EPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSE 499 L+EN ++ + GG+I + +G + EV + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------TKES 310 Query: 500 RGVGLALVKQQVENLGG---SIAVESEPGIFTQFFVQIP 535 G GL V+++++ L G I + + G V IP Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 26.8 bits (59), Expect = 0.011 Identities = 9/28 (32%), Positives = 16/28 (57%) Query: 32 LAIIEHTDVDESLKGQGIGKQLVAKVVE 59 A+IE V + + +G+G L+ K +E Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIE 116
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.8 bits (67), Expect = 0.023 Identities = 36/190 (18%), Positives = 66/190 (34%), Gaps = 14/190 (7%) Query: 44 NHAISLFSAYA-SLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL 102 H L + YA P+LG +DR G R ++ + + ++ + L Sbjct: 43 AHYGILLALYALMQFACAPVLGAL-SDRF-GRRPVLLVSLAGAAVDYAIMAT-APFLWVL 99 Query: 103 YLALAIIICGYGLFKSNISCLLGELYDEND-HRRDGGFSLLYAAGNIGSIAAPIACGLAA 161 Y+ + G+ + + + D D R F + A G +A P+ GL Sbjct: 100 YIGRIV----AGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 162 QWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKF-ALPVWSWLVVMLC 220 + H F A + L FL+G + +++ L L + W M Sbjct: 156 G-FSPHAPFFAAA---ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTV 211 Query: 221 LAPVFFTLLL 230 +A + + Sbjct: 212 VAALMAVFFI 221
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 36.8 bits (85), Expect = 7e-05 Identities = 16/97 (16%), Positives = 36/97 (37%), Gaps = 7/97 (7%) Query: 391 PLDEKQLAALNTEIDNIVTLPELNNLS-----IIYQIKAVSALVKGKTDESYQAINTGID 445 ++ A+ + + T+ LN +S +Y + A + GK +++++ Sbjct: 6 TDTQEYQLAMESFLKGGGTIAMLNEISSDTLEQLYSL-AFNQYQSGKYEDAHKVFQALCV 64 Query: 446 LEMSWLNYVL-LGKVYEMKGMNREAADAYLTAFNLRP 481 L+ + L LG + G A +Y + Sbjct: 65 LDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDI 101
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.6 bits (105), Expect = 5e-08 Identities = 28/188 (14%), Positives = 51/188 (27%), Gaps = 13/188 (6%) Query: 3 REDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPDKEAILYDALRYLSQQIDV 62 R+ +L AL+L QG+++T+L +A+ + + DK + + I Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 63 WRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIAACTFYPDPGH----PIHQLA 118 + L + E + F+ + Q Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLEST--VTEERRRLLMEIIFHKCEFVGEMAVVQQAQ 130 Query: 119 DQQKSAAYDFTHELLTT-------LEVDDPAMVAKQMELVLEGCLSRMLVNRSQADVDTA 171 +YD + L A M + G + L D+ Sbjct: 131 RNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKE 190 Query: 172 HRLAEDIL 179 R IL Sbjct: 191 ARDYVAIL 198
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 27.3 bits (60), Expect = 0.010 Identities = 11/48 (22%), Positives = 21/48 (43%), Gaps = 9/48 (18%) Query: 36 TRGEVLAVGNGRILENGE--VKPLDVKV-------GDIVIFNDGYGVK 74 T E+ A+G ++L +++ G++V ND GV+ Sbjct: 244 TLAELEAMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVE 291
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 50.8 bits (121), Expect = 2e-08 Identities = 50/312 (16%), Positives = 105/312 (33%), Gaps = 18/312 (5%) Query: 121 SRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDS 180 + ++ QERA + N L + +D ++ LT L+ + Sbjct: 49 TDTLEKVQERADKFEIENNTLKLKNSDLSFNNKALKDHNDELTE---ELSNAKEKLRKND 105 Query: 181 ARLKALVDEL-ELAQLSANNRQELARLRSELAEKES--QQLDAYLQALRNQLNSQRQLEA 237 L ++ EL A+ + L + + + L+A AL + + + Sbjct: 106 KSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAAR-KADLEKAL 164 Query: 238 ERALESTELLAENSADLPKDIVAQFKINRELSAALNQQAQRMDLVASQQRQAASQTLQVR 297 E A+ + + L + A EL AL +++ + ++ + Sbjct: 165 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALA 224 Query: 298 QALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQQLDTEMAQLRVQRLRYEDLLNKQ 357 L + L + A A++ L + L+ A+L + Sbjct: 225 ARKADLEKA---LEGAMNFSTADSAKIKTLEA--EKAALEARQAELEKALEGAMNFSTAD 279 Query: 358 PLLRQIHQADGQPLTAE------QNRILEAQLRTQRELLNSLLQGGDTLLLELTKLKVSN 411 + +A+ L AE Q+++L A ++ R L++ + L E KL+ N Sbjct: 280 SAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQN 339 Query: 412 GQLEDALKEVNE 423 E + + + Sbjct: 340 KISEASRQSLRR 351 Score = 42.7 bits (100), Expect = 7e-06 Identities = 48/239 (20%), Positives = 92/239 (38%), Gaps = 23/239 (9%) Query: 20 ATAPDSKQITQELEQAKAAKPAQPEVVEALQSALNALEERKGSLER-IKQYQQVIDNYPK 78 A A + + LE A A ++ L++ ALE R+ LE+ ++ Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSA 281 Query: 79 LSATLRAQLNNMRDEPRSVSPGMSTDALNQEILQVSSQLLDKSRQAQQEQERAREIADSL 138 TL A+ + E + + Q + LD SR+A+++ E + + Sbjct: 282 KIKTLEAEKAALEAEKADL---EHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Query: 139 NQLPQQQTDARRQLNEIERRLGTLTGNTPLNQAQNFALQSDSARLKAL--VDELELAQLS 196 N++ ++A RQ + R L L+++ +L+ + E L Sbjct: 339 NKI----SEASRQ--SLRRDLDASR-------EAKKQLEAEHQKLEEQNKISEASRQSLR 385 Query: 197 AN---NRQELARLRSELAEKESQQLDAYLQALRNQLNSQRQLEAERALESTELLAENSA 252 + +R+ ++ L E S +L A + + S++ E E+A +L AE A Sbjct: 386 RDLDASREAKKQVEKALEEANS-KLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKA 443
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.019 Identities = 28/134 (20%), Positives = 45/134 (33%), Gaps = 11/134 (8%) Query: 329 VLQQQLETPLPLDDEPQPAPRSIPENRVAAGRNHFAEPAAREPVAPRYTP---APASGSR 385 +Q E + + EP+P P E V + +PV P SR Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESR 124 Query: 386 PAAPWPNAQPGYQ---KQQGEVYRQLLQTPAPMQKLKAPEPQEPALAANSQSFGRVLTIV 442 PA+P+ N P + + + + L +PQ PA A + G+V Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKF 184 Query: 443 HSDCALLERDGNIS 456 + DG + Sbjct: 185 D-----VTPDGRVD 193
>SECA#SecA protein signature. Length = 901 Score = 30.6 bits (69), Expect = 0.016 Identities = 25/144 (17%), Positives = 53/144 (36%), Gaps = 6/144 (4%) Query: 282 HVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLEDFEPRIDRDEENK-PNRV 340 ++D +DV N + IDA+ P L ++ + + R+ D + P Sbjct: 665 ELLDVSDVSETINSIREDVFKATIDAYIPPQSL--EEMWDIPGLQERLKNDFDLDLPIAE 722 Query: 341 WLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKEWMEEDGSV 400 WL + L + + + + + + R + LQ ++ W E ++ Sbjct: 723 WLDKEPELHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAM 782 Query: 401 SLQVRMPIVDWRRLCKQEPALIDY 424 +R I R +++P +Y Sbjct: 783 D-YLRQGIH-LRGYAQKDP-KQEY 803
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.006 Identities = 25/81 (30%), Positives = 30/81 (37%), Gaps = 10/81 (12%) Query: 17 GSSKPGGNSEGNGNKGGRDQGPPDLDDIFRKLSKKLGGLGGGKGTGSGGGSSSQGP---- 72 S G +SE N GG G G GGG GTG G S+ P Sbjct: 33 ASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTG-GNLSAVAAPVAFG 91 Query: 73 -----RPQLGGRVVTIAAAAI 88 P GG V+I+A A+ Sbjct: 92 FPALSTPGAGGLAVSISAGAL 112
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 30.6 bits (69), Expect = 0.029 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 165 VVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAV-GKIVEVLGDNM 218 +VP+D L L+ I +G ++++ P R + GK+ + D + Sbjct: 359 IVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAI 413
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.5 bits (61), Expect = 0.037 Identities = 6/19 (31%), Positives = 7/19 (36%), Gaps = 2/19 (10%) Query: 105 FNGDVQI--ELTGYWTWEQ 121 F G + L W EQ Sbjct: 62 FKGQEDLGNGLKAIWQVEQ 80
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 84.3 bits (208), Expect = 1e-21 Identities = 68/249 (27%), Positives = 113/249 (45%), Gaps = 22/249 (8%) Query: 6 GKTVLILGGSRGIGAAIVRRFVTDGANVR-FTYAGSKD---AAKRLAQETGATAVFTDSA 61 GK I G ++GIG A+ R + GA++ Y K + A+ A A D Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 62 DRDAVIDVV----RKSGALDILVVNAGIGVFGEALELNADDIDRLFKINIHAPYHASVEA 117 D A+ ++ R+ G +DILV AG+ G L+ ++ + F +N ++AS Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 118 ARQMP--EGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGLARDFGPRGITINVVQ 175 ++ M G I+ +GS N +P MAAYA+SK+A + L + I N+V Sbjct: 128 SKYMMDRRSGSIVTVGS-NPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 176 PGPIDTDA--------NPANGPMRDMLHSL---MAIKRHGQPEEVAGMVAWLAGPEASFV 224 PG +TD N A ++ L + + +K+ +P ++A V +L +A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 225 TGAMHTIDG 233 T +DG Sbjct: 247 TMHNLCVDG 255
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.0 bits (119), Expect = 7e-10 Identities = 20/117 (17%), Positives = 43/117 (36%), Gaps = 7/117 (5%) Query: 5 KQSRVPGRPRRFAPEQAISAAKVLFHQKGFDAVSVAEVTDYLGINPPSLYAAFGSKAGLF 64 ++++ + R + + A LF Q+G + S+ E+ G+ ++Y F K+ LF Sbjct: 3 RKTKQEAQETR---QHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 65 SRVLNEYVGT----EAIPLADILRDDRPVGECLVEVLKEAARRYSQNGGCAGCMVLE 117 S + E A D V ++ + E+ + + + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK 116
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 31.1 bits (70), Expect = 0.013 Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 4/63 (6%) Query: 199 NNLQKLNNLLKLNNIQGLNNPQELNNPQNLNDSQELNNSQELNSPQELNDPQELNNSQDL 258 N L++ + N NNP +NP N N+ NN E N+P N+P +N D Sbjct: 272 NFLKQNIEDIHFANDDQPNNP---DNPDNPNNPDNPNNPDEPNNPDNPNNPDNPDNG-DN 327 Query: 259 NNS 261 NNS Sbjct: 328 NNS 330
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 144 bits (365), Expect = 1e-44 Identities = 86/256 (33%), Positives = 133/256 (51%), Gaps = 8/256 (3%) Query: 7 LAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVEKLHQEGIQAVAAPFN 66 + GK ITG+AQGIG +A L GA I D E+ E V L E A A P + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 67 VTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQ 126 V ID IE+++GPID+LVN AG+ R ++EW +VN T VF S+ Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 AVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGI 186 +V+++M++R++G ++ + S + + R ++ YA+SK A M T+ + +ELA +NI+ N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 187 APGYFKTEMTKALVEDE--------AFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDF 238 +PG +T+M +L DE P + P ++ A +FL S + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 239 VNGHLLFVDGGMLVAV 254 + H L VDGG + V Sbjct: 246 ITMHNLCVDGGATLGV 261
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.2 bits (120), Expect = 6e-09 Identities = 49/310 (15%), Positives = 121/310 (39%), Gaps = 20/310 (6%) Query: 69 FFGAMADKYGRKPMMMWAIFIYSVGTGLSGIATNLYMLAVCRFIVGL-GMSGEYACASTY 127 GA++D++GR+P+++ ++ +V + A L++L + R + G+ G +G A A Y Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATG--AVAGAY 119 Query: 128 AVESWPKNLQSKASAFLVSGFSVGNIIAAQIIPQFAEVYGWRNSFFI-----GLLPVLLV 182 + + +++ F+ + F G ++A ++ + FF GL + Sbjct: 120 IADITDGDERARHFGFMSACFGFG-MVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGC 178 Query: 183 LWIRKSAPESQEWIEDKYKDKSTFLSVFRKPHLSISMIVFLVCFCLFGANWPINGLLPSY 242 + +S + + + + + FR + + F + + L Sbjct: 179 FLLPESHKGERR--PLRREALNPL-ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI 235 Query: 243 LADNGVNTVVISTLMTIAGLG---TLTGTIFFGFVGDKIGVKKAFVVGLITSFIFLCPLF 299 ++ + + +++A G +L + G V ++G ++A ++G+I L Sbjct: 236 FGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLA 295 Query: 300 FISVKNSSLIGLCLFGLM-FTNLGIAGLVPKFIYDYFPTKLRGLGTGLIYNLGATGGMAA 358 F + + + L + ++ + + + +L+G L + + Sbjct: 296 FATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALT----SLTSIVG 351 Query: 359 PVLATYISGY 368 P+L T I Sbjct: 352 PLLFTAIYAA 361
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 64.2 bits (156), Expect = 6e-14 Identities = 44/240 (18%), Positives = 92/240 (38%), Gaps = 13/240 (5%) Query: 36 TPQRIVVLELSFADALAAVDVIPIGIADDNDAKRILPEVRAHLKPWQSVGTRAQPSLEAI 95 P RIV LE + L A+ ++P G+AD + + + E VG R +P+LE + Sbjct: 34 DPNRIVALEWLPVELLLALGIVPYGVADTINYRLWVSE-PPLPDSVIDVGLRTEPNLELL 92 Query: 96 AALKPDLIIADSSRHAGVYIALQQIAPVLLLKSR--NETYAENLQSAAIIGEMVGKKREM 153 +KP ++ S+ + L +IAP + A +S + +++ + Sbjct: 93 TEMKPSFMVW-SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAA 151 Query: 154 QARLEQHKERMAQWASQLPKGTR---VAFGTSREQQFNLHTQETWTGSVLASLGLNVPAA 210 + L Q+++ + + K + + + + +L G +P A Sbjct: 152 ETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYG--IPNA 209 Query: 211 MAGAS----MPSIGLEQLLAVNPAWLLVAHYREESIVKRWQQDPLWQMLTAAQKQQVASV 266 G + ++ +++L A +L + + PLWQ + + + V Sbjct: 210 WQGETNFWGSTAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRV 269
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.006 Identities = 20/77 (25%), Positives = 30/77 (38%), Gaps = 10/77 (12%) Query: 85 LAVIPEYQGMGVGGRLIRTGIE--------HLRLMGCQTVFVLGHATYYPRHGFEPCAGD 136 +AV +Y+ GVG L+ IE L L Q + + +Y +H F A D Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLE-TQDINISA-CHFYAKHHFIIGAVD 152 Query: 137 KGYPAPYPIPEEHKACW 153 + +P E W Sbjct: 153 TMLYSNFPTANEIAIFW 169
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 30.2 bits (68), Expect = 0.007 Identities = 9/51 (17%), Positives = 24/51 (47%) Query: 138 LHAVDARVNELEELLPLLMKDKLLAKGVSHLLSSQLTRILRTHAAMSVLGH 188 + V+ +VN+ +P L + + +++ +S L +S + + A + Sbjct: 80 VSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSE 130
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 142 bits (361), Expect = 7e-40 Identities = 83/387 (21%), Positives = 149/387 (38%), Gaps = 84/387 (21%) Query: 5 IGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQDGET------LVGQPAKRQA 58 + IDLGT N+ + + + E PS++A QD VG AK+ Sbjct: 13 LSIDLGTANTLIYVKGQGIV-LNE--------PSVVAIRQDRAGSPKSVAAVGHDAKQML 63 Query: 59 VTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAWVEVKGQKMAPPQISAE 118 P N + AI+ + +D I F + + Sbjct: 64 GRTPGN-IAAIRPM-----------KDGVIADFFVTEK------------------MLQH 93 Query: 119 VLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRIAGLEVKRIINEPTAAALA 178 +K++ + P ++ VP +R+A +++ + AG +I EP AAA+ Sbjct: 94 FIKQVHS---NSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIG 150 Query: 179 YGL--DKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEVLATNGDTHLGGEDFDSRL 236 GL + TG+ V D+GGGT ++++I ++ V + +GG+ FD + Sbjct: 151 AGLPVSEATGS---MVVDIGGGTTEVAVISLNGV---------VYSSSVRIGGDRFDEAI 198 Query: 237 INYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA----QQTDVNLPYITADATG 292 INY+ + G + AE+ K E+ SA + ++ + Sbjct: 199 INYVRRNYGSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGV 245 Query: 293 PKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQD-AGLSVSDIDD--VILVGGQTRMPMV 349 P+ + + LE+L E + + + VAL+ SDI + ++L GG + + Sbjct: 246 PRGFTLN-SNEILEALQEP-LTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNL 303 Query: 350 QKKVAEFFGKEPRKDVNPDEAVAIGAA 376 + + E G +P VA G Sbjct: 304 DRLLMEETGIPVVVAEDPLTCVARGGG 330
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 61.4 bits (149), Expect = 4e-17 Identities = 18/46 (39%), Positives = 30/46 (65%) Query: 23 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 68 +++ ++++C+T ++ +TRK LCE+ R G EVA F AYES Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>HOKGEFTOXIC#Hok/Gef cell toxic protein family signature. Length = 52 Score = 60.6 bits (147), Expect = 5e-17 Identities = 18/46 (39%), Positives = 30/46 (65%) Query: 4 HKAMIVALIVICITAVVAALVTRKDLCEVHIRTGQTEVAVFTAYES 49 +++ ++++C+T ++ +TRK LCE+ R G EVA F AYES Sbjct: 5 RSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGYREVAAFMAYES 50
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 28.2 bits (63), Expect = 0.037 Identities = 17/69 (24%), Positives = 28/69 (40%), Gaps = 10/69 (14%) Query: 187 FISGTGFAMDYRRLSGHALKGSEIIRLVEESDPVAELALRRYELRLAKSLAHVVNILDP- 245 +G + D+R L A + D A+LAL + R+ K++ + Sbjct: 273 VYGISGISSDFRDLEDAAF---------KNGDKRAQLALNVFAYRVKKTIGSYAAAMGGV 323 Query: 246 DVIVLGGGM 254 DVIV G+ Sbjct: 324 DVIVFTAGI 332
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.1 bits (125), Expect = 1e-09 Identities = 74/356 (20%), Positives = 126/356 (35%), Gaps = 35/356 (9%) Query: 5 ILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGH---MISYYALGVVVGAPIIALF 61 + ++AL G+G+ IM VL L ++ S H +++ YAL AP++ Sbjct: 11 LSTVALDAVGIGL----IMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 62 SSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSGFPHGAFFGVGAIVLSKIIK 121 S R+ + +LL +A + A+ + +L IGR+V+G GA + I Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD--IT 124 Query: 122 PGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTFLLIAVFNIAVMASVYFWVPDI 181 G A G +S ++ P+ L FS F A N + F +P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 182 RDEAKGNLREQ----------FHFLRSPAPWLI--FAATMFGNAGVFAWFSYVKPYMMFI 229 + LR + + A + F + G W + Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFG------E 238 Query: 230 SGFSETAMTFIMMLVGLGM---VLGNMLSGRISGRYSPLRIAAVTDFIIVLALLMLFFCG 286 F A T + L G+ + M++G ++ R R + ++L F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 287 GMKTTSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAF--NLGSAVG 340 I + G+ LQ +L + E G G +A +L S VG Sbjct: 299 RGWMAFPIMVLLASGGIG--MPALQAMLSRQV-DEERQGQLQGSLAALTSLTSIVG 351
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 41.4 bits (97), Expect = 2e-05 Identities = 27/204 (13%), Positives = 61/204 (29%), Gaps = 18/204 (8%) Query: 487 EARIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 EA ++ Q + Q ++E + E + +E + L Sbjct: 133 EADTLKTQSSLLQARLEQ---TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT- 188 Query: 547 ATLRGQLDAITKQLQRDENEAQSLRQDEQALTQQWQAVTASLNITLQPLDDIQPWLDAQD 606 + ++ Q Q + E R + + + + LDD L Q Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 607 -------EHERQL-RLLSQRHELQGQIAAHNQQIIQYQQQIEQRQQLLLTTLTGYALTLP 658 E E + +++ + Q+ +I+ +++ + QL L Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLF------KNEILD 302 Query: 659 QEDEEESWLATRQQEAQSWQQRQN 682 + + + E ++RQ Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQ 326 Score = 35.6 bits (82), Expect = 0.001 Identities = 35/199 (17%), Positives = 72/199 (36%), Gaps = 13/199 (6%) Query: 671 QQEAQSWQQRQNELTALQNRIQQLTPILETLPQSDELPHCEETVVLENWRQVHEQCLALH 730 + + Q + Q R Q L+ +E + E + +V + Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK 192 Query: 731 SQQQTLQQQDVLAAQSLQKAQAQFDTAL--------QASVFDDQQAFLAALMDEQTLTQL 782 Q T Q Q +L K +A+ T L + V + ++L+ +Q + + Sbjct: 193 EQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKH 252 Query: 783 EQLKQNLENQRRQAQTLVTQTAETLAQHQQHRPDDGLALTVTVEQIQQELAQTHQKLREN 842 L+Q EN+ +A + L Q + + + + E+ KLR+ Sbjct: 253 AVLEQ--ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL---DKLRQT 307 Query: 843 TTSQGEIRQQLKQDADNRQ 861 T + G + +L ++ + +Q Sbjct: 308 TDNIGLLTLELAKNEERQQ 326 Score = 33.3 bits (76), Expect = 0.005 Identities = 25/212 (11%), Positives = 65/212 (30%), Gaps = 19/212 (8%) Query: 375 QTSDREHLRQWQQQLTHAEQKLNALAAITLTLTADEV------ATALAQHAEQRPLRQHL 428 + Q L A + ++ ++ +++ Q+ + + + Sbjct: 129 ALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLT 188 Query: 429 VALHGQIVPQQKRLAQLQVAIQNVTQEQTQRNAALNEMRQRYKEKTQQLADVKTICEQEA 488 + Q Q + Q ++ + E+ A +N + + +L D ++ ++A Sbjct: 189 SLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQA 248 Query: 489 --RIKTLEAQRAQLQAGQPCPLCGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEG 546 + LE + ++A + Y++ + L A E Sbjct: 249 IAKHAVLEQENKYVEAVN-----------ELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297 Query: 547 ATLRGQLDAITKQLQRDENEAQSLRQDEQALT 578 + +L T + E + +QA Sbjct: 298 NEILDKLRQTTDNIGLLTLELAKNEERQQASV 329
>FRAGILYSIN#Fragilysin metallopeptidase (M10C) enterotoxin signature. Length = 405 Score = 29.7 bits (66), Expect = 0.022 Identities = 13/70 (18%), Positives = 23/70 (32%), Gaps = 4/70 (5%) Query: 149 KQQHLLAAITDYYQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFP 208 K+ ++ I ++Y + + + I T D + + I A Sbjct: 135 KEAQMMNEIAEFYAAPFKKTRAINEKEAFECI-YDSRTRSA--GKD-IVSVKINIDKAKK 190 Query: 209 AQNFPPADYI 218 N P DYI Sbjct: 191 ILNLPECDYI 200
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.9 bits (236), Expect = 1e-24 Identities = 33/149 (22%), Positives = 62/149 (41%), Gaps = 9/149 (6%) Query: 4 RILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNEPWPDLILLDWMLPGGSGIQ 63 ILV +D+A IR ++ L + G+ + + + DL++ D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 64 FIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDYITKPFSPKELVARIKAVMRRI 123 + +K+ D+PV++++A+ ++ E GA DY+ KPF EL+ I + Sbjct: 65 LLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 124 SPMAVEEVIEMQGLSLDPTSHRVMAGEEP 152 E L D + G Sbjct: 121 -----EPKRRPSKLEDDSQDGMPLVGRSA 144
>PF06580#Sensor histidine kinase Length = 349 Score = 34.1 bits (78), Expect = 0.001 Identities = 19/105 (18%), Positives = 33/105 (31%), Gaps = 26/105 (24%) Query: 325 LVYNAVNH----TPEGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKAR 380 LV N + H P+G I ++ + VE+ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 381 SRQTGGSGLGLAIVKHAVNH---HESRLNIESTVGKGTRFSFVIP 422 +G GL V+ + E+++ + GK +IP Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 71/347 (20%), Positives = 135/347 (38%), Gaps = 20/347 (5%) Query: 62 KFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLEPGTQLRWMAALAVVIAFCS 121 +F +P++ + F RR LL + V A M W+ + ++A + Sbjct: 56 QFACAPVLGALSDRF--GRRPVLLVSLAGAAVDYAIMAT----APFLWVLYIGRIVAGIT 109 Query: 122 ASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSGGLALWLADKWLGWQGMYWLMA 181 + V A+ D+ +ER + GM+ L + ++ A Sbjct: 110 GATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG--FSPHAPFFAAA 167 Query: 182 AL-LIPCIIATLLAPEP--TDTIPVPKTLEQAVVAPLRDFFGRNNAWLILLLIVLYKLGD 238 AL + + L PE + P+ + + + A L+ + ++ +G Sbjct: 168 ALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQ 227 Query: 239 AFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGALYGGILMQRLSLFRALLIFGIL 298 A +L F +DA +G+ G+L ++ A+ G + RL RAL+ G++ Sbjct: 228 VPA-ALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM-LGMI 285 Query: 299 QGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGTSAFVALLMTLCNKSFSATQFALLS 358 A GY LL+ + + V GG+G A A+L ++ L+ Sbjct: 286 --ADGTGYILLAFATRGWMAFPIMVLL--ASGGIGMPALQAMLSRQVDEERQGQLQGSLA 341 Query: 359 ALSAVGRVYVGPVAGWFVEAHGWSTF--YLFSVAAAVPGLILLLVCR 403 AL+++ + VGP+ + A +T+ + + AA+ L L + R Sbjct: 342 ALTSLTSI-VGPLLFTAIYAASITTWNGWAWIAGAALYLLCLPALRR 387
>PF06291#Lambda prophage Bor protein Length = 102 Score = 26.5 bits (58), Expect = 0.027 Identities = 11/34 (32%), Positives = 18/34 (52%) Query: 3 KKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQ 36 KK+LF ++ GCA+ T+ PT P++ Sbjct: 7 KKMLFSAALAMLITGCAQQTFTVGNKPTAVTPKE 40
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.043 Identities = 16/73 (21%), Positives = 29/73 (39%), Gaps = 13/73 (17%) Query: 60 ERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIG 119 E P+ E + ++G+ A + +Y RL D +++ G Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQ----EIYRVLARLMQTD---------LTLMITG 167 Query: 120 PTGSGKTLLAETL 132 +G+GK L+A L Sbjct: 168 ESGTGKELVARAL 180
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.3 bits (78), Expect = 0.002 Identities = 34/133 (25%), Positives = 68/133 (51%), Gaps = 15/133 (11%) Query: 191 ERLEYLMAMMESEIDLLQVEKRIRNRVKKQMEKSQREYYLNEQMKAIQKELGEMDDAPD- 249 LE A +E + +L R +++ ++ S+ +Q++A ++L E + + Sbjct: 291 AALEAEKADLEHQSQVLNAN---RQSLRRDLDASREAK---KQLEAEHQKLEEQNKISEA 344 Query: 250 ENEALKRKIDAAKMPKEAKEKAEAELQKLKMMSPMS-AEATVVRGYIDWMVQVPWNARSK 308 ++L+R +DA++ EAK++ EAE QKL+ + +S A +R +D + A+ + Sbjct: 345 SRQSLRRDLDASR---EAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASRE----AKKQ 397 Query: 309 VKKDLRQAQEILD 321 V+K L +A L Sbjct: 398 VEKALEEANSKLA 410
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (294), Expect = 3e-38 Identities = 49/88 (55%), Positives = 67/88 (76%) Query: 2 NKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVALVGFGTFAVKERAARTGR 61 NK LI K+A +++K + A+DA+ ++V+ L +G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEITIAAAKVPSFRAGKALKDAV 89 NPQTG+EI I A+KVP+F+AGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>OMPTIN#Omptin serine protease signature. Length = 317 Score = 527 bits (1359), Expect = 0.0 Identities = 317/317 (100%), Positives = 317/317 (100%) Query: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS Sbjct: 1 MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGKTKERVYLAEEGGRKVS 60 Query: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR Sbjct: 61 QLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMVDQDWMDSSNPGTWTDESR 120 Query: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI Sbjct: 121 HPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYSFTARGGSYIYSSEEGFRDDI 180 Query: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT 240 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT Sbjct: 181 GSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTFKYSGWVESSDNDEHYDPGKRIT 240 Query: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGA 300 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGA Sbjct: 241 YRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRVTNKKGNTSLYDHNNNTSDYSKNGA 300 Query: 301 GIENYNFITTAGLKYTF 317 GIENYNFITTAGLKYTF Sbjct: 301 GIENYNFITTAGLKYTF 317
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 28/190 (14%), Positives = 66/190 (34%), Gaps = 46/190 (24%) Query: 306 EELTRMAKMVSDML-FLAQADNNQLIPEKKMLNLADEVGKVFDFFEALAEDRGVELRFVG 364 + M +S+++ + + N + + LADE+ V + + ++F Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQVS------LADELTVVDSYLQLA------SIQF-E 237 Query: 365 DKCQV-------AGDPLMLRRALSNLLSNALRY----TPTGETIVVRCQTVDHLVQVIVE 413 D+ Q D + + L+ N +++ P G I+++ + V + VE Sbjct: 238 DRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVE 297 Query: 414 NPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLAIVK---SIVVAHKGTVAVTSDAR 470 N G+ E +G GL V+ ++ + + ++ Sbjct: 298 NTGSLALKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 471 GTRFVITLPA 480 ++ +P Sbjct: 340 KVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 35/117 (29%), Positives = 62/117 (52%) Query: 2 KLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGDYDLIILDIMLPDVNGWD 61 +L+ +D+ L + L+ AG+ V + N + GD DL++ D+++PD N +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKPFAFAELLARVRTLLRR 118 ++ ++ A +P+L+++A T +K E GA DYL KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 4e-05 Identities = 25/189 (13%), Positives = 60/189 (31%), Gaps = 13/189 (6%) Query: 254 QAQTVNSDSLQSVKLPA-GLSSQILLQRPDIMEAEHALM-----AANANIGAARAAFFPS 307 + +S + +K + +I+++ + + L+ A A+ ++ Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQS----- 141 Query: 308 ISLTSGISTASSDLSSLFNASSGMWNFIPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYE 367 SL + + + + P F + L + + ++Q Sbjct: 142 -SLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN 200 Query: 368 QKIQNAFKEVADALALRQSLNDQISAQQRYLASLQITLQRARALYQHGAVSYLEVLDAER 427 QK Q + A R ++ +I+ + + L +L A++ VL+ E Sbjct: 201 QKYQ-KELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQEN 259 Query: 428 SLFATRQTL 436 L Sbjct: 260 KYVEAVNEL 268
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 25.9 bits (57), Expect = 0.033 Identities = 9/56 (16%), Positives = 24/56 (42%), Gaps = 1/56 (1%) Query: 3 KALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVVKGIDLESKKITIHH 58 + +++ + SL + A+ E + ++ Q+ G++ +DL S + Sbjct: 2 RYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMI-EMDLASGRTLTAW 56
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 695 bits (1794), Expect = 0.0 Identities = 214/1059 (20%), Positives = 440/1059 (41%), Gaps = 54/1059 (5%) Query: 1 MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSDVQVIIKTSYPGQAPQI 60 M + IRR + A+ L + G I+ PV P ++ V + +YPG Q Sbjct: 1 MANFFIRR----PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQT 56 Query: 61 VENQVTYPLTTTMLSVPGAKTVRGFSQ-FGDSYVYVIFEDGTDPYWARSRVLEYLNQVQG 119 V++ VT + M + + S G + + F+ GTDP A+ +V L Sbjct: 57 VQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATP 116 Query: 120 KLPAGVSAELGP-DATGVGWIYEYALVDRSGKHDLADLRSLQDWFLKYELKTIPDVAEVA 178 LP V + + + ++ V + D+ +K L + V +V Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 SVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAGGSSIELA------EAEYMVR 232 G ++ +D L +Y ++ +V + L N + + + + Sbjct: 177 LFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 ASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQIGPEMRRGIAELNGEGEVAGGVVILR 292 A + ++F + L+ + +G V L+DVA+V++G E IA +NG+ AG + L Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLA 294 Query: 293 SGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRAIDNLSGKLLEEFIVVAVV 352 +G NA + A+K KL L+ P+G++++ YD + + +I + L E ++V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 CALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMSLGGIAIAVGAMVDAAIVMIE 412 LFL ++R+ L+ I++P+ L F ++ G + N +++ G+ +A+G +VD AIV++E Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 413 NAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPALFISLLIITLSFIPIFTLEGQEG 472 N + + E D + + ++ AL ++++ FIP+ G G Sbjct: 415 NVERVMME----------DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 473 RLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGKIPPESSNPLNRF----------LI 522 ++ + T AMA + L+A+++ P L ++ + E F + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKP-VSAEHHENKGGFFGWFNTTFDHSV 523 Query: 523 RVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQINEGDLLYMPSTLPGISA 582 Y + K+L LL+ AL V ++ ++ FLP+ ++G L M G + Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 583 AEAASMLQKTDKLIM--SVPEVARVFGKTGKAETATDSAPLEMVETTIQLKPQEQW-RPG 639 +L + + V VF G + + + LKP E+ Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQN---AGMAFVSLKPWEERNGDE 640 Query: 640 MTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIGIKVSGTVLADI-DAMAE 698 + + +I + + + +++ + I +G + A + Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQ 700 Query: 699 QIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTVADVQLFVTSAVGGAMVGE 758 + A+ + S LE +E+++EKA G++++D+ +++A+GG V + Sbjct: 701 LLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVND 760 Query: 759 TVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITLADVADIKVSTGPSMLKTENA 818 ++ + ++ +R P+ + +L + + + + + G L+ N Sbjct: 761 FIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNG 820 Query: 819 RPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSVAFSGQFELLERANHKLKLMVPM 878 P+ I +A L + +A K L G ++G + ++ +V + Sbjct: 821 LPSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAI 878 Query: 879 TLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWLLWWMGFHLSVATGTGFIALAGVAA 938 + +++F+ L + + ++ VP +VG + V G + G++A Sbjct: 879 SFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSA 938 Query: 939 EFGVVMLMYLRHAIEAVPSLNNPQTFSEQKLDEALYHGAVLRVRPKAMTVAVIIAGLLPI 998 + ++++ + + +E + + EA +R+RP MT I G+LP+ Sbjct: 939 KNAILIVEFAKDLMEK----------EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPL 988 Query: 999 LWGTGAGSEVMSRIAAPMIGGMITAPLLSLFIIPAAYKL 1037 GAGS + + ++GGM++A LL++F +P + + Sbjct: 989 AISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVV 1027
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 47.2 bits (112), Expect = 3e-08 Identities = 36/146 (24%), Positives = 63/146 (43%), Gaps = 5/146 (3%) Query: 197 AREREQGTLDQLLVSPLTTWQIFIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALF 256 R Q T + +L + L I +G+ A A IG+ A + + L+L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGA---GIGVVAAALGYTQWLSLL 148 Query: 257 YFTMVI--YGLSLVGFGLLISSLCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQN 314 Y VI GL+ G+++++L + + + P + LSG V PV+ +P+ Q Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQT 208 Query: 315 LTWINPIRHFTDITKQIYLKDASLDI 340 P+ H D+ + I L +D+ Sbjct: 209 AARFLPLSHSIDLIRPIMLGHPVVDV 234
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.012 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 21/90 (23%) Query: 293 TPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKELTKKFGDFAATDHVNFAV 352 PR E + +LG P + + + K HV + Sbjct: 547 VPRLEKWLVHVLGKTPDDYKP-------------RRLRYLQLVGKYI----LMGHVARVM 589 Query: 353 KRGEIFG----LLGPNGAGKSTTFKMMCGL 378 + G F L G G GKST + GL Sbjct: 590 EPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619 Score = 29.3 bits (65), Expect = 0.047 Identities = 11/23 (47%), Positives = 13/23 (56%) Query: 34 YVTGLVGPDGAGKTTLMRMLAGL 56 Y L G G GK+TL+ L GL Sbjct: 597 YSVVLEGTGGIGKSTLINTLVGL 619
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 62.9 bits (153), Expect = 4e-13 Identities = 42/259 (16%), Positives = 92/259 (35%), Gaps = 25/259 (9%) Query: 83 ALMQAKAGVSVAQAQYDLMLAGYRNEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRT 142 Q + + +A+ +LA E + + + + L + Sbjct: 201 QKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENK 260 Query: 143 ISA--NDLENARSSRDQAQATLKSAQDKLRQYRSGNREQ---DIAQAKASLEQAQAQLAQ 197 N+L +S +Q ++ + SA+++ + + + + Q ++ +LA+ Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAK 320 Query: 198 AELNLQDSTLIAPSDGTLLTRAV-EPGTVLNEGGTVFTVSLT-RPVWVRAYVDERNLDQA 255 E Q S + AP + V G V+ T+ + + V A V +++ Sbjct: 321 NEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 256 QPGRKVLLYTDGRPDKPYH---GQIGFVSPTAEFTPKTVETPDLRTDLVYRLRIVVT--- 309 G+ ++ + P Y G++ ++ A D R LV+ + I + Sbjct: 381 NVGQNAIIKVEAFPYTRYGYLVGKVKNINLDA--------IEDQRLGLVFNVIISIEENC 432 Query: 310 ----DADDALRQGMPVTVQ 324 + + L GM VT + Sbjct: 433 LSTGNKNIPLSSGMAVTAE 451
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.7 bits (178), Expect = 7e-18 Identities = 33/214 (15%), Positives = 77/214 (35%), Gaps = 17/214 (7%) Query: 9 KGEQAKKQLIAAALAQFGEYGMNATT-REIAAQAGQNIAAITYYFGSKEDLYLACAQWIA 67 + ++ ++ ++ AL F + G+++T+ EIA AG AI ++F K DL+ + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 68 DFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRACRNMIKLLTQDDTVNLSKFISREQL 127 IGE E + P + +RE+++ + + + + + F E + Sbjct: 68 SNIGELEL---EYQAKFPGDP---LSVLREILIHVLESTVTEERRRLLMEII-FHKCEFV 120 Query: 128 SPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDANDTRMILHTHALIGEILAFRLGKETIL 187 A + + + + + +A L T + + G Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKH--CIEAKMLPADLMTRRAAIIMRGYISG----- 173 Query: 188 LRTGWTAFDEEKTELINQTVTCHIDLILQGLSQR 221 L W + + + ++ ++L+ Sbjct: 174 LMENWLFAPQSFD--LKKEARDYVAILLEMYLLC 205
>SECA#SecA protein signature. Length = 901 Score = 29.8 bits (67), Expect = 0.025 Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 4/67 (5%) Query: 246 QQVLVFTRTKHGANHLAEQLNKDGIRSAAIHG-NKSQGARTRALADFKSGDIRVLVATDI 304 Q VLV T + + ++ +L K GI+ ++ + A A A + + V +AT++ Sbjct: 450 QPVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNM 506 Query: 305 AARGLDI 311 A RG DI Sbjct: 507 AGRGTDI 513
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.2 bits (102), Expect = 8e-07 Identities = 41/201 (20%), Positives = 64/201 (31%), Gaps = 34/201 (16%) Query: 16 AFLFLFAPTAFAAEQTVEAPSVDARAW----------ILMDYASGKVLAEGNADEKLDPA 65 + L A A P + I MD ASG+ L ADE+ Sbjct: 7 CIISLLATLPLAV-HASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMM 65 Query: 66 SLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGNPALRGSSVMFLKPGDQVSVADLN 125 S K++ V + A +L + + +P V D ++V +L Sbjct: 66 STFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSP------VSEKHLADGMTVGELC 119 Query: 126 KGVIIQSGNDACIALADYVAGSQESFIGLMNGYAKKLGLTNTT---FQTVHGLDAPGQF- 181 I S N A L V G + + +++G T ++T PG Sbjct: 120 AAAITMSDNSAANLLLATVGGPAG-----LTAFLRQIGDNVTRLDRWETELNEALPGDAR 174 Query: 182 --STARDMA------LLGKAL 194 +T MA L + L Sbjct: 175 DTTTPASMAATLRKLLTSQRL 195
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.8 bits (93), Expect = 1e-05 Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 23/269 (8%) Query: 71 LLGPLSDRIGRRPVMLAGVVWFIVTCLAILLAQNIEQFTLLRFLQGISLCFIGAVGYAAI 130 +LG LSDR GRRPV+L + V + A + + R + GI+ GAV A I Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYI 120 Query: 131 QESFEEAVCIKITALMANVALIAPLLGPLVG---AAWIHVLPWEGMFVLFAALAAISFFG 187 + + + M+ + GP++G + P F AAL ++F Sbjct: 121 ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAP----FFAAAALNGLNFLT 176 Query: 188 LQRAMPETATRIGEKLSLKELGRDYKLVLKNG-RFVAGALALGFVSLPLLAWIAQSP--I 244 +PE+ L + L G VA +A+ F ++ + Q P + Sbjct: 177 GCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFF----IMQLVGQVPAAL 232 Query: 245 IIITGEQLSSYEYGLLQVPIFGALIAGNL----LLARLTSRRTVRSLIIMGGWPIMIGLL 300 +I GE ++ + + + I +L + + +R R +++G G + Sbjct: 233 WVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYI 292 Query: 301 VAAAATVISSHAYLWMTAGLSIYAFGIGL 329 + A AT ++ + + + GIG+ Sbjct: 293 LLAFAT----RGWMAFPIMVLLASGGIGM 317
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.7 bits (77), Expect = 0.001 Identities = 34/150 (22%), Positives = 65/150 (43%), Gaps = 6/150 (4%) Query: 218 LLIGVVVLAMAFAEGSANDWL-PLLMVDGHGFSP-TSGSLIYAGFTLGMTVGRFTGGWFI 275 +IGV+ + F + + P +M D H S GS+I T+ + + + GG + Sbjct: 258 FMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILV 317 Query: 276 DRYSRVAVVR-ASALM--GALGIGLIIFVDSAWVA-GVSVVLWGLGASLGFPLTISAASD 331 DR + V+ + L ++ S ++ + VL GL + TI ++S Sbjct: 318 DRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSL 377 Query: 332 TGPDAPTRVSVVATTGYLAFLVGPPLLGYL 361 +A +S++ T +L+ G ++G L Sbjct: 378 KQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 4e-10 Identities = 14/81 (17%), Positives = 31/81 (38%) Query: 2 RRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGSMTYYFSGIDELLLEAFS 61 + + R+ I+ L G+ + + +IA AGV G++ ++F +L E + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 62 SFTEIMSRQYQAFFSDVSDAP 82 + + + P Sbjct: 65 LSESNIGELELEYQAKFPGDP 85
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.1 bits (73), Expect = 0.006 Identities = 21/106 (19%), Positives = 34/106 (32%), Gaps = 6/106 (5%) Query: 394 LMIGMITFQFSTFSFGMGNAAGLLFAGIML-GFMRANHPTFG-YIPQ--GALSMVKEFGL 449 L++ + +L+ G ++ G A G YI + FG Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF 135 Query: 450 MVFMAGVGLSAGSGINNGLGAIGGQM--LIAGLIVSLVPVVICFLF 493 M G G+ AG + +G A + L + CFL Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLL 181
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.010 Identities = 9/18 (50%), Positives = 12/18 (66%) Query: 31 LVLLGPSGAGKSSLLRVL 48 +VL G G GKS+L+ L Sbjct: 599 VVLEGTGGIGKSTLINTL 616
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 28.0 bits (62), Expect = 0.041 Identities = 20/54 (37%), Positives = 26/54 (48%), Gaps = 9/54 (16%) Query: 2 RRFFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRIKVLVIHYTADD 55 R+ LV ALL AG A I K+G +LD Y ++ L HY +DD Sbjct: 3 RKVLALVIPALLAAGAAHAAEIYNKDGNKLDL-------YGKVDGL--HYFSDD 47
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 75.2 bits (185), Expect = 2e-17 Identities = 70/363 (19%), Positives = 123/363 (33%), Gaps = 65/363 (17%) Query: 1 MKVLVTGATSGLGRNAVEFLCQKGISVRA---------TGRNEAMGKLLEKMGAEFVPAD 51 MK LVTGA +G + + L + G V +A +LL + G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LTELVSSQAKVMLAGIDTLWHCS-------SFTSPWGTQQAFDLANVRATRRLGEWAVAW 104 L + + ++ S +P A+ +N+ + E Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPH----AYADSNLTGFLNILEGCRHN 116 Query: 105 GVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQTRFT 164 +++ ++ SS S+Y + D + +A +K A+E + + S T Sbjct: 117 KIQHLLYASSSSVYGL-NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSH-LYGLPAT 174 Query: 165 ILRPQSLFGPHDK--VFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLASQEA 222 LR +++GP + + + + M SI + + G D TY ++ A+ Sbjct: 175 GLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVI 234 Query: 223 CDKLPS--------------GRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLD 268 RVYNI N L +Q L D L I+ + +P D Sbjct: 235 PHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGD 294 Query: 269 MIARSMERLGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVITLDEGIEKTAAW 328 + T D E +G+ P T+ +G++ W Sbjct: 295 V----------------LETS-----------ADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 329 LRD 331 RD Sbjct: 328 YRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 55.6 bits (134), Expect = 1e-10 Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 17/125 (13%) Query: 4 RILVLGASGYIGQHLVRTLSQQGHQILA---------AARHVDRLAKLQLANVSCHKVDL 54 + LV GA+G+IG H+ + L + GHQ++ + RL L HK+DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 55 SWPDNLPALLQD--IDTVYFLVH------SMGEGGDFIAQERQVALNVRDALREVPVKQL 106 + + + L + V+ H S+ + LN+ + R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 107 IFLSS 111 ++ SS Sbjct: 122 LYASS 126
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 27.9 bits (62), Expect = 0.021 Identities = 19/90 (21%), Positives = 32/90 (35%), Gaps = 8/90 (8%) Query: 9 LFLLGLTWGCELFAHDGTVNISGSFRRNTCVLAQDSKQINVQLGDVSLTRFSHGNYGPEK 68 F + L C A + F N LA D + L+RF +G P Sbjct: 25 GFFVRLFVACAFAAQAPLSSAELYF--NPRFLADDPQ------AVADLSRFENGQELPPG 76 Query: 69 SFIINLQDCGTDVSTVDVTFSGTPDGVQSE 98 ++ +++ ++T DVTF+ Sbjct: 77 TYRVDIYLNNGYMATRDVTFNTGDSEQGIV 106
>CHLAMIDIAOMP#Chlamydia major outer membrane protein signature. Length = 393 Score = 28.4 bits (63), Expect = 0.044 Identities = 19/67 (28%), Positives = 28/67 (41%), Gaps = 8/67 (11%) Query: 137 GVNGDAVDPKSVTSWADL------WKPEYKGSLLLTDDAREVFQMALRKLGYSGNTTDPK 190 G GD DP T+W D + ++ +L D + FQM + +GN T P Sbjct: 42 GFGGDPCDP--CTTWCDAISMRMGYYGDFVFDRVLKTDVNKEFQMGDKPTSTTGNATAPT 99 Query: 191 EIEAAYN 197 + A N Sbjct: 100 TLTAREN 106
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.0 bits (67), Expect = 0.017 Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 46 LTLLGPSGCGKTTVLRLIAGLE-TVDSGRIMLDNED 80 + L G G GK+T++ + GL+ D+ + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKD 634
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.048 Identities = 11/69 (15%), Positives = 22/69 (31%), Gaps = 20/69 (28%) Query: 389 NACKYCLE------FVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQ 442 N K+ + + + + + + + VE+ G + +E Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE--------------ST 311 Query: 443 GVGLAVARE 451 G GL RE Sbjct: 312 GTGLQNVRE 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 6e-22 Identities = 31/124 (25%), Positives = 62/124 (50%) Query: 2 RVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHIPDIAIVDLGLPDEDGLS 61 +LV +D+A +R L + AG+ V +A ++ D+ + D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKPFHIEEVMARMQALMRRNSG 121 L+ R + LP+LV++A+ ++ ++ GA DY+ KPF + E++ + + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 LASQ 125 S+ Sbjct: 125 RPSK 128
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 143 bits (361), Expect = 3e-39 Identities = 62/206 (30%), Positives = 102/206 (49%), Gaps = 1/206 (0%) Query: 258 GKAFYYQPVLCTVQAKSTLTVEEEQDRLRQAIDFTLLDLMTLTAKAEASGLDDIAAIFSG 317 KAF + ++ S V E ++L A++ + +L + + EAS D A IF+ Sbjct: 17 AKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKAEIFAA 76 Query: 318 HHTLLDDPELLAAASELLQHEHCTAEYAWQQVLKELSQQYQQLDDEYLQARYIDVDDLLH 377 H +LDDPEL+ +++E AEYA ++V ++ +D+EY++ R D+ D+ Sbjct: 77 HLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMKERAADIRDVSK 136 Query: 378 RTLVHLT-QTKEELPQFNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPVSHSALIAR 436 R L HL L T+++AE++ PS QL+ VKG G SHSA+++R Sbjct: 137 RVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTSHSAIMSR 196 Query: 437 ELGIGWICQQGEKLYAIQPEETLTLD 462 L I + E IQ + + +D Sbjct: 197 SLEIPAVVGTKEVTEKIQHGDMVIVD 222
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 28.5 bits (63), Expect = 0.019 Identities = 10/47 (21%), Positives = 26/47 (55%) Query: 138 VESLRQSSEQNLSVPVALEAASSIAESAAQSTITMQARKGRASYLGE 184 E++ + ++N + +EA ++A +A + + A+ G+A+ G+ Sbjct: 293 REAVDRWIQENPNAAETVEAVFNVAAAAKVAKLAKAAKPGKAAVSGD 339
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 244 bits (625), Expect = 6e-76 Identities = 91/363 (25%), Positives = 155/363 (42%), Gaps = 33/363 (9%) Query: 308 QMRQLMTSQLGKVSHTFAHMPQDDPQTRRLIHFGRQAARSSFPVLLCGEEGVGKALLSQA 367 + S+L S + + + + ++ +++ GE G GK L+++A Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARA 179 Query: 368 IHNESERAAGPYIAVNCELYGDAALAEEFIG---GDRTDNENGRLSRLELAHGGTLFLEK 424 +H+ +R GP++A+N + E G G T + R E A GGTLFL++ Sbjct: 180 LHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDE 239 Query: 425 IEYLAVELQSALLQVIKQGVITRLDARRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYA 484 I + ++ Q+ LL+V++QG T + R I DV+++A T DL + Q F LYY Sbjct: 240 IGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYR 299 Query: 485 LHAFEITIPPLRMRRGSIPALVNNKLRSLEKRFSTRLKIDDDALARLVSCAWPGNDFELY 544 L+ + +PPLR R IP LV + ++ EK + D +AL + + WPGN EL Sbjct: 300 LNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 545 SVIENLALSSDNGRIRVSDLPEHLFTEQATDDVSATRLSTS------------------- 585 +++ L I + L +E + + Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 586 -----------LSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRKMKQHGIDAGQ 634 AE+E I+ A T G + + LLG+ R TL +K+++ G+ + Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYR 479 Query: 635 FKR 637 R Sbjct: 480 SSR 482
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 214 bits (545), Expect = 9e-60 Identities = 242/979 (24%), Positives = 400/979 (40%), Gaps = 115/979 (11%) Query: 14 RLAELKIRSPSIQLIKFGAIGLNAIIFSPLLIAADTGSQYGTNITINDGDRI---TGDTA 70 + A L+ + ++ L GA ++ I Q+G +I +D + +G T Sbjct: 10 KAAPLRRTTLAMALGALGAAPAAHADWNNQSIVKTGERQHGIHIQGSDPGGVRTASGTTI 69 Query: 71 DPSGN-LYGVMTPAGNTPGNINLGNDVTVN---VNDASGYAKGIIIQGKNSSLTANRLTV 126 SG G++ N + N + ++D + K L A+ T+ Sbjct: 70 KVSGRQAQGILLE--NPAAELQFRNGSVTSSGQLSDDGIRRFLGTVTVKAGKLVADHATL 127 Query: 127 DVVGQT---SAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSNGIG 183 VG T I + + G+ A + ST++ G+ I + +T + I + G+ Sbjct: 128 ANVGDTWDDDGIALYVAGEQAQASIAD-STLQGAG-GVQIERGANVTVQRSAIVD-GGLH 184 Query: 184 LTINDYGTSVDLGSGSKITTDGS-TGVYIGGLNGNNANGAARFTATDLTID---VQGYSA 239 + DL + D + T V G + A++LT+D + G A Sbjct: 185 IGALQSLQPEDLPPSRVVLRDTNVTAVPASGAPA----AVSVLGASELTLDGGHITGGRA 240 Query: 240 MGINVQKNSVVDLGTNSTIKTNGDNAHGLWSFGQVSANAL-------TVDVTGAAANGVE 292 G+ + +VV L +TI+ A G G V A+ GV+ Sbjct: 241 AGVAAMQGAVVHL-QRATIRRGDAPAGGAVPGGAVPGGAVPGGFGPGGFGPVLDGWYGVD 299 Query: 293 VRGGTTTIGADSHISSAQGGGLVTSGSDAIINFTGTAAQRNSIFSGGSYGASAQTATAVV 352 V G + + A S + + + G + G A + +G + +G +T A Sbjct: 300 VSGSSVEL-AQSIVEAPELGAAIRVGRGARVTVSGGSLS-------APHGNVIETGGARR 351 Query: 353 NM-QNTDITVD-RNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDLV 410 Q +++ + G+ A G L L +TG A A+G T + + Sbjct: 352 FAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTSI- 410 Query: 411 IDMSTPDQMAIATQHDDGYAASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLSD 470 P +A+A+ + WTG++ Sbjct: 411 ----GPLDVALAS------------------------------------QARWTGAT--R 428 Query: 471 NVNGGKLDVAMNNSVWNVTSNSNLDTLAL-SHSTVDFASHGSTAGTFATLNVENLSGNST 529 V+ +D N+ W +T NSN+ L L S +VDF + AG F L V L+G+ Sbjct: 429 AVDSLSID----NATWVMTDNSNVGALRLASDGSVDFQQ-PAEAGRFKVLTVNTLAGSGL 483 Query: 530 FIMRADVVGEGNGVNNKGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAAS 589 F M D L + ++G H L +RN GSE + N +L V AA+ Sbjct: 484 FRMNV------FADLGLSDKLVVMQDASGQHRLWVRNSGSEPASANTLLLVQTPLGSAAT 537 Query: 590 FSASS---QVELGGYLYDVRKNG-TNWELYASGTVPEPTPNPEPTPAPAQPPIVNPD-PT 644 F+ ++ +V++G Y Y + NG W L + P P P P+P P P QPP P+ P Sbjct: 538 FTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPGPQPPQPPQPQPEAPA 597 Query: 645 PEPAPTPKPTTTADAGGNYLNVGYL--LNYVENRTLMQRMGDLRNQSKDGNIWLRSYG-- 700 P+P + + A+A N VG L Y E+ L +R+G+LR G W R + Sbjct: 598 PQPPAGRELSAAANAAVNTGGVGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQR 657 Query: 701 GSLDSFASGKLSGFDMGYSGIQFGGDKRLSDVM-PLYVGLYIGSTHASPDYSG-GDGTAR 758 LD+ A + FD +G + G D ++ ++G G T ++G G G Sbjct: 658 QQLDNRAGRR---FDQKVAGFELGADHAVAVAGGRWHLGGLAGYTRGDRGFTGDGGGHTD 714 Query: 759 SDYMGMYASYMAQNGFYSDLVIKASRQKNSFHVLDSQNNGVNANGTANGMSISLEAGQRF 818 S ++G YA+Y+A +GFY D ++ASR +N F V S V +G+ SLEAG+RF Sbjct: 715 SVHVGGYATYIADSGFYLDATLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRF 774 Query: 819 NLSPTGYGFYIEPQTQLTYSHQNEMTMKASNGLNIHLNHYESLLGRASMILGYDIT-AGN 877 + G+++EPQ +L +A+NGL + S+LGR + +G I AG Sbjct: 775 THAD---GWFLEPQAELAVFRAGGGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAGG 831 Query: 878 SQLNVYVKTGAIREFSGDTEYLLNNSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADYT 937 Q+ Y+K ++EF G N + +G G+G++A + H+ Y +Y+ Sbjct: 832 RQVQPYIKASVLQEFDGAGTVHTNGIAHRTELRGTRAELGLGMAAALGRGHSLYASYEYS 891 Query: 938 QGNLFDQK-QVNGGYRFSF 955 +G + GYR+S+ Sbjct: 892 KGPKLAMPWTFHAGYRYSW 910
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 33.0 bits (75), Expect = 0.003 Identities = 24/81 (29%), Positives = 37/81 (45%), Gaps = 16/81 (19%) Query: 288 LGAIESLLCAV----VL---DGMTGTKHKANSELVGQGLGNI---IAPFF------GGIT 331 L + +L A+ +L D T TK A EL + LGN+ I+ + G++ Sbjct: 242 LDTVSGILSAISASFILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLS 301 Query: 332 ATAAIARSAANVRAGATSPIS 352 +AA A A+ A SP+S Sbjct: 302 TSAAAAGLIASAVTLAISPLS 322
>INTIMIN#Intimin signature. Length = 939 Score = 257 bits (658), Expect = 5e-79 Identities = 120/378 (31%), Positives = 197/378 (52%), Gaps = 21/378 (5%) Query: 79 GEQAKAFALGKVRDALSQQVNQHVESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDN 138 G+ AK ALG + Q + +++WL +G A V+++ N F GS + +P D+ Sbjct: 184 GDYAKDTALGIAGN----QASSQLQAWLQHYGTAEVNLQSGNN--FDGSSLDFLLPFYDS 237 Query: 139 DRYLTWSQLGLTQQDNGLVSNVGVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWG 198 ++ L + Q+G D+ +N+G GQR+ ++GYN F D + R G G E W Sbjct: 238 EKMLAFGQVGARYIDSRFTANLGAGQRFFLPENMLGYNVFIDQDFSGDNTRLGIGGEYWR 297 Query: 199 EYLRLSANFYQPFAAWHE--QTATQEQRMARGYDLTARMRMPFYQHLNTSVSLEQYFGDR 256 +Y + S N Y + WHE ++R A G+D+ +P Y L + EQY+GD Sbjct: 298 DYFKSSVNGYFRMSGWHESYNKKDYDERPANGFDIRFNGYLPSYPALGAKLMYEQYYGDN 357 Query: 257 VDLFNSGTGYHNPVALSLGLNYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKK 316 V LFNS NP A ++G+NYTP+PLVT+ ++ G EN + Y+F P + Sbjct: 358 VALFNSDKLQSNPGAATVGVNYTPIPLVTMGIDYRHGTGNENDLLYSMQFRYQFDKPWSQ 417 Query: 317 QLSAGEVAESQSLRGSRYDNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQI 376 Q+ V E ++L GSRYD QRNN LEY+++ L++ + + T ++L + Sbjct: 418 QIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI-PHDINGTERSTQKIQLIV 476 Query: 377 RSRYGIRQLIWQGDTQILS-----LTPGAQANSAEGWTLIMPDWQNGEGASNHWRLSVVV 431 +S+YG+ +++W D+ + S G+Q SA+ + I+P + +G SN ++++ Sbjct: 477 KSKYGLDRIVWD-DSALRSQGGQIQHSGSQ--SAQDYQAILPAYV--QGGSNVYKVTARA 531 Query: 432 EDNQGQRVSSNEITLTLV 449 D G SSN + LT+ Sbjct: 532 YDRNGN--SSNNVLLTIT 547
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.7 bits (181), Expect = 2e-17 Identities = 32/117 (27%), Positives = 56/117 (47%), Gaps = 2/117 (1%) Query: 7 ATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQGIELAESLDPDLILLDLNMPGMN 66 ATIL+ DD +RT + Q +S A + SN + D DL++ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRGADGYLLKDMEPEDLLKALHQA 123 + L ++++ ++V S N + A ++GA YL K + +L+ + +A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 53.3 bits (128), Expect = 1e-09 Identities = 36/172 (20%), Positives = 73/172 (42%), Gaps = 23/172 (13%) Query: 424 PESSRELLSQIRNELNASWAQLRELLTTFRLQLTEPGLRPALEASCEEYSAKFGFPVKLD 483 P +RE+L+ + + S + +LT +++ + S +F ++ + Sbjct: 190 PTKAREMLTSLSELMRYSLRYSNARQVSLADELT------VVDSYLQLASIQFEDRLQFE 243 Query: 484 YQLPPRL----VPSHQAIHLLQIAREALSNALKH-----SQASEVVVTVAQNDNQVKLTV 534 Q+ P + VP L+Q E N +KH Q ++++ +++ V L V Sbjct: 244 NQINPAIMDVQVPPM----LVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 535 QDNGCGVPENAIRSNHYGMIIMRDRAQSLRG-DCRVRRRESGGTEVVVTFIP 585 ++ G +N S G+ +R+R Q L G + +++ E G + IP Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.011 Identities = 35/166 (21%), Positives = 60/166 (36%), Gaps = 22/166 (13%) Query: 258 IMSLLYLATFGSFIGFSAGFAMLSKTQFPDVQILQYAFFGPFIGALARSA---GGALSDR 314 I+S + L+ + I A A L K + + FFG F S ++ Sbjct: 474 IVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKI 533 Query: 315 LGGTRVTLVNFILMAIFSGLLFLTLPTD----GQGGSFMAFFAVFLALFLTAGLGSGSTF 370 LG T L+ + L+ +LFL LP+ G F+ L +G+T Sbjct: 534 LGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTM----------IQLPAGATQ 583 Query: 371 QMISVIFRKLTMDRVKAEGGSDER-----AMREAATDTAAALGFIS 411 + + ++T +K E + E + A + F+S Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVS 629
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.5 bits (222), Expect = 4e-24 Identities = 30/105 (28%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 7 KFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGVDALNKLQAGGYGFVISDWNMPNMDGL 66 LV DD + +R ++ L G++ V + + AG V++D MP+ + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYD-VRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 ELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAGASGYVVKPF 111 +LL I+ LPVL+++A+ I A++ GA Y+ KPF Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPF 106
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 8e-14 Identities = 35/188 (18%), Positives = 72/188 (38%), Gaps = 23/188 (12%) Query: 1 MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDLIKKFNPDVLTLDVEMP 60 M+ +L DD A +R ++ + ++ V + I + D++ DV MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 RMDGLDFLEKLMRLRPMPVVMVSSLTGKGS-EVTLRALELGAIDFVTKPQLGIREGMLAY 119 + D L ++ + RP V+V ++ + + ++A E GA D++ KP + E + Sbjct: 59 DENAFDLLPRIKKARPDLPVLV--MSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGII 115 Query: 120 NEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIAIGASTGGTEAIRHVLQPLP 179 +AE R +K + + +G S E R + + + Sbjct: 116 GRALAEPKRRPSKLEDDSQDGMP-----------------LVGRSAAMQEIYRVLARLMQ 158 Query: 180 LSSPALLI 187 ++ Sbjct: 159 TDLTLMIT 166
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.010 Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 11/93 (11%) Query: 46 LISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPNIEE 105 L +SSP A P + G + ++ PGGGDD GE +++ Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAG---AGTDPGGPGGGDD-----GEDPFGEWLDD 435 Query: 106 LKKRM---EQSRLRKLRGDLDQLIESDPKLRAL 135 R+ + L+ R L + + S P L Sbjct: 436 EVARLRLRGRWLLKPRRAALIEALRSAPALAGC 468
>PF05844#YopD protein Length = 295 Score = 33.1 bits (75), Expect = 0.001 Identities = 12/28 (42%), Positives = 22/28 (78%), Gaps = 2/28 (7%) Query: 76 MDLLALLYRLMAKSRQMGMFSLERDIEN 103 ++LL +L+R+ K+R++G+ L+RD EN Sbjct: 74 VELLLILFRIAQKARELGV--LQRDNEN 99
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 50.1 bits (120), Expect = 8e-09 Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 20/129 (15%) Query: 132 AMMLH-IRQQAQAQLPEAITQAVIGRPINFQGLGGDEANTQAQGILERAAKRAGFRDVVF 190 M+ H I+Q + ++ P+ + + + I E +A+ AG R+V Sbjct: 89 KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQV-------ERRAIRE-SAQGAGAREVFL 140 Query: 191 QYEPVAAGLDYEATLQEEKRVLVVDIGGGTTDCSLLLMGPQWRSRLDREASLLGHSGCRI 250 EP+AA + + E +VVDIGGGTT+ +++ + ++ S RI Sbjct: 141 IEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVAVISLN-----------GVVYSSSVRI 189 Query: 251 GGNDLDIAL 259 GG+ D A+ Sbjct: 190 GGDRFDEAI 198 Score = 37.4 bits (87), Expect = 9e-05 Identities = 33/137 (24%), Positives = 57/137 (41%), Gaps = 23/137 (16%) Query: 332 RLSYRLV---RSAEECKIALSSV--AETRASLPFISNELAT------LISQRGLESALSQ 380 R +Y + +AE K + S + + LA ++ + AL + Sbjct: 203 RRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQE 262 Query: 381 PLTRILEQVQLALDNAQEKPDV--------IYLTGGSARSPLIKKALAEQLPGIPIAGGD 432 PLT I+ V +AL+ Q P++ + LTGG A + + L E+ GIP+ + Sbjct: 263 PLTGIVSAVMVALE--QCPPELASDISERGMVLTGGGALLRNLDRLLMEET-GIPVVVAE 319 Query: 433 D-FGSVTAGLARWAEVV 448 D V G + E++ Sbjct: 320 DPLTCVARGGGKALEMI 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 48.7 bits (116), Expect = 3e-08 Identities = 47/369 (12%), Positives = 106/369 (28%), Gaps = 87/369 (23%) Query: 4 SYKSRWVIVIVVVIAAIAAFWFWQGRNDSRSAAPG-----ATKQAQQSPAGGRRG---MR 55 S + R V ++ IA G+ + + A G + + ++ Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 56 SG-------PLA---PVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDG--QLIALHF 103 G L + A + L T ++ ++ +L Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 104 QEGQQVKAGDLLAEI------------DPSQFKVALAQAQGQLA-------KDKATLANA 144 Q V ++L Q ++ L + + + + + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 145 RRDLARYQQLAKTNLVSRQELDAQQALVSETEGTIKADEASVA----------------- 187 + L + L +++ + Q+ E ++ ++ + Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 188 --------------------------SAQLQLDWSRITAPVDGRV-GLKQVDVGNQISSG 220 + + S I APV +V LK G +++ Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 221 DTTGIVVITQTHPIDLVFTLPESDIATVVQAQKAGKPLVVEAWDRTNSKKL-SEGTLLSL 279 +T +V++ + +++ + DI + Q A + VEA+ T L + ++L Sbjct: 354 ETL-MVIVPEDDTLEVTALVQNKDIGFINVGQNA--IIKVEAFPYTRYGYLVGKVKNINL 410 Query: 280 DNQIDATTG 288 D D G Sbjct: 411 DAIEDQRLG 419
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 920 bits (2379), Expect = 0.0 Identities = 300/1036 (28%), Positives = 513/1036 (49%), Gaps = 29/1036 (2%) Query: 13 SRLFIMRPVATTLLMVAILLAGIIGYRALPVSALPEVDYPTIQVVTLYPGASPDVMTSAV 72 + FI RP+ +L + +++AG + LPV+ P + P + V YPGA + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 73 TAPLERQFGQMSGLKQMSSQS-SGGASVITLQFQLTLPLDVAEQEVQAAINAATNLLPSD 131 T +E+ + L MSS S S G+ ITL FQ D+A+ +VQ + AT LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 132 LPNPPVYSKVNPADPPIMTLAVTSTAMPMTQVE--DMVETRVAQKISQISGVGLVTLSGG 189 + + S + +M S TQ + D V + V +S+++GVG V L G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 190 QRPAVRVKLNAQAIAALGLTSETVRTAITGANVNSAKGSLDGP------SRAVTLSANDQ 243 Q A+R+ L+A + LT V + N A G L G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 244 MQSAEEYRQLII-AYQNGAPIRLGDVATVEQGAENSWLGAWANKEQAIVMNVQRQPGANI 302 ++ EE+ ++ + +G+ +RL DVA VE G EN + A N + A + ++ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 303 ISTADSIRQMLPQLTESLPKSVKVTVLSDRTTNIRASVDDTQFELMMAIALVVMIIYLFL 362 + TA +I+ L +L P+ +KV D T ++ S+ + L AI LV +++YLFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 363 RNIPATIIPGVAVPLSLIGTFAVMVFLDFSINNLTLMALTIATGFVVDDAIVVIENISRY 422 +N+ AT+IP +AVP+ L+GTFA++ +SIN LT+ + +A G +VDDAIVV+EN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 423 I-EKGEKPLAAALKGAGEIGFTIISLTFSLIAVLIPLLFMGDIVGRLFREFAITLAVAIL 481 + E P A K +I ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 482 ISAVVSLTLTPMMCARML---SQESLRKQNRFSRASEKMFDRIIAAYGRGLAKVLNHPWL 538 +S +V+L LTP +CA +L S E + F FD + Y + K+L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 539 TLSVALSTLLLSVLLWVFIPKGFFPVQDNGIIQGTLQAPQSSSFANMAQRQRQVADVILQ 598 L + + V+L++ +P F P +D G+ +Q P ++ + QV D L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 599 DPA--VQSLTSFVGVDGTNPSLNSARLQINLKPLDERDDR---VQKVIARLQTAVDKVPG 653 + V+S+ + G + + N+ ++LKP +ER+ + VI R + + K+ Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR- 658 Query: 654 VDLFLQPTQDLTIDTQVSRTQYQFTLQ---ATSLDALSTWVPQLMEKLQQLP-QLSDVSS 709 D F+ P I + T + F L DAL+ QL+ Q P L V Sbjct: 659 -DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 710 DWQDKGLVAYVNVDRDSASRLGISMADVDNALYNAFGQRLISTIYTQANQYRVVLEHNTE 769 + + + VD++ A LG+S++D++ + A G ++ + ++ ++ + + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 770 NTPGLAALDTIRLTSSDGGVVPLSSIAKIEQRFAPLSINHLDQFPVTTISFNVPDNYSLG 829 +D + + S++G +VP S+ + + + P I S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 830 DAVQAIMDTEKTLNLPVDITTQFQGSTLAFQSALGSTVWLIVAAVVAMYIVLGILYESFI 889 DA A+M+ + LP I + G + + + L+ + V +++ L LYES+ Sbjct: 838 DA-MALMENLAS-KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 890 HPITILSTLPTAGVGALLALLIAGSELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQ 949 P++++ +P VG LLA + + DV ++G++ IG+ KNAI++++FA ++ Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 950 GMSPREAIYQACLLRFRPILMTTLAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQV 1009 G EA A +R RPILMT+LA +LG LPL +S G G+ + +GIG++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1010 LTLFTTPVIYLLFDRL 1025 L +F PV +++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 922 bits (2385), Expect = 0.0 Identities = 288/1035 (27%), Positives = 507/1035 (48%), Gaps = 36/1035 (3%) Query: 6 LFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPVIIVSASLPGASPETMASSVAT 65 FI RP+ +L++ + + G L LPVA P + P + VSA+ PGA +T+ +V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERSLGRIAGVSEMTSSS-SLGSTRIILQFDFDRDINGAARDVQAAINAAQSLLPSGMP 124 +E+++ I + M+S+S S GS I L F D + A VQ + A LLP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SRPTYRKANPSDAPIMILTLTSDT--YSQGELYDFASTQLAPTISQIDGVGDVDVGGSSL 182 + S + +M+ SD +Q ++ D+ ++ + T+S+++GVGDV + G+ Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRVGLNPQALFNQGVSLDDVRTAVSNANVRKPQG------ALEDGTHRWQIQTNDELK 236 A+R+ L+ L ++ DV + N + G AL I K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 TAAEYQPLIIHYN-NGGAVRLGDVATVTDSVQDVRNAGMTNAKPAILLMIRKLPEANIIQ 295 E+ + + N +G VRL DVA V ++ N KPA L I+ AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEVEQTLIISVALVILVVFLFLRS 355 T +I+AKL ELQ P + + D +P ++ S+ EV +TL ++ LV LV++LFL++ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 GRATIIPAVSVPVSLIGTFAAMYLCGFSLNNLSLMALTIATGFVVDDAIVVLENIARHL- 414 RAT+IP ++VPV L+GTFA + G+S+N L++ + +A G +VDDAIVV+EN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLLLMGGLPGRLLREFAVTLSVAIGIS 474 E + P +A + ++ ++ +++ L AVF+P+ GG G + R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 LLVSLTLTPMMCGWMLKASKPREQKRLRGFG----RMLVALQQGYGKSLKWVLNHTRLVG 530 +LV+L LTP +C +LK + GF Y S+ +L T Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 531 VVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQADQSISFQ----AMRGKLQDFMKII 586 ++ +A + L++ +P +F PE+D GV + IQ + + + ++K Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 587 RD-DPAVDNVTGFT-GGSRVNSGMMFITLKPRDERS---ETAQQIIDRLRVKLAKEPGAN 641 + +V V GF+ G N+GM F++LKP +ER+ +A+ +I R +++L K Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 642 LFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRKKLATL-----PELADVNSD 696 + + I G + ++ L D + + R +L + L V + Sbjct: 662 VIPFNMPAIVELGTATGFDFE---LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 697 QQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRY 756 ++ A+ L D++ LG+ + N ++ A G ++ K+ ++ D ++ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 757 TQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGLSAASTISFNLPTGKSLSD 816 ++K++V + G+ +P S F + + I G S D Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 817 ASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILIIAAIATVYIVLGILYESYVH 876 A A ++ ++L P+ + + G + + + N L+ + V++ L LYES+ Sbjct: 839 AMALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSI 896 Query: 877 PLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRHGN 936 P++++ +P VG LLA LFN + ++G++ IG+ KNAI++V+FA + Sbjct: 897 PVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956 Query: 937 LTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQLL 996 EA A +R RPI+MT+LA + G LPL +S G GS + +GI ++GG+V + LL Sbjct: 957 KGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLL 1016 Query: 997 TLYTTPVVYLFFDRL 1011 ++ PV ++ R Sbjct: 1017 AIFFVPVFFVVIRRC 1031 Score = 79.9 bits (197), Expect = 3e-17 Identities = 77/446 (17%), Positives = 162/446 (36%), Gaps = 26/446 (5%) Query: 592 VDNVTGFTGGS-RVNSGMMFITLKPRDERSETAQQIIDRLRVKLAKEPGANLFLMAVQDI 650 +DN+ + S S + +T + + Q+ ++L++ P + Q I Sbjct: 72 IDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE----VQQQGI 127 Query: 651 RVGGRQSNASYQYTLLSDDLAALREW-----EPKIRKKLATLPELADVNSDQQDNGAE-- 703 V S+ +SD+ ++ ++ L+ L + DV GA+ Sbjct: 128 SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL----FGAQYA 183 Query: 704 MNLVYDRDTMARLGID----VQAANSLLNNAFGQRQISTIYQPMNQYKVVMEVDPRYTQD 759 M + D D + + + + + + T P Q + R+ Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNP 243 Query: 760 ISALEKMFVINNEGKAIPLSYFAK--WQPANAPLSVNHQGLSAASTISFNLPTGKSLSDA 817 + +N++G + L A+ N + G AA +L D Sbjct: 244 EEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL-DT 302 Query: 818 SAAIDRAMTQL--GVPSTVRGSFA-GTAQVFQETMNSQVILIIAAIATVYIVLGILYESY 874 + AI + +L P ++ + T Q +++ V + AI V++V+ + ++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 875 VHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLIGIVKKNAIMMVDFALEAQRH 934 L +P +G L F + + + G++L IG++ +AI++V+ Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 935 GNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSGGDGSELRQPLGITIVGGLVMSQ 994 L P+EA ++ ++ + +P+ GG + + ITIV + +S Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 995 LLTLYTTPVVYLFFDRLRLRFSRKPK 1020 L+ L TP + + + K Sbjct: 483 LVALILTPALCATLLKPVSAEHHENK 508
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (310), Expect = 8e-33 Identities = 98/435 (22%), Positives = 190/435 (43%), Gaps = 25/435 (5%) Query: 20 FMQSLDTTIVNTALPSMAQSLGESPLHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFF 79 F L+ ++N +LP +A + P + V +++LT ++ G L+D++G++ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 80 TAIVLFTLGSLFCALSGTLNELL-LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTF 138 I++ GS+ + + LL +AR +QG G A + + V + +P+E A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 139 VTLPGQVGPLLGPALGGLLVEYASWHWIFLINIPVGIIGAIATLL-LMPNYTMQTRRFDL 197 + +G +GPA+GG++ Y HW +L+ IP+ I + L+ L+ FD+ Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 198 SGFLLLAVGMAVLTLALDGSKGTGLSPLTIAGLVAVGVVALVLYLLHARNNNRALFSLKL 257 G +L++VG+ L + L V V++ ++++ H R L Sbjct: 202 KGIILMSVGIVFFMLFTTSYSISFLI---------VSVLSFLIFVKHIRKVTDPFVDPGL 252 Query: 258 FRTRTFSLGLAGSFAGRIGSGMLPFMTPVFLQIGLGFSPFHAG-LMMIPMVLGSMGMKRI 316 + F +G+ M P ++ S G +++ P + + I Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 317 VVQVVNRFGYRRVLVATTLGLSLVTLLFMTTALL----GWYYVLPFVLFLQGMVNSTRFS 372 +V+R G VL +G++ +++ F+T + L W+ + V L G+ S + Sbjct: 313 GGILVDRRGPLYVL---NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL--SFTKT 367 Query: 373 SMNTLTLKDLPDNLASSGNSLLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVF 432 ++T+ L A +G SLL+ LS G+ I G LL + + Q+ + Sbjct: 368 VISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQSTY 427 Query: 433 MYT--WLSMALIIAL 445 +Y+ L + II + Sbjct: 428 LYSNLLLLFSGIIVI 442
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 31.0 bits (70), Expect = 0.010 Identities = 27/95 (28%), Positives = 35/95 (36%), Gaps = 20/95 (21%) Query: 164 RQTSWLIVALATLLAALATFLLA------RGLLAPVKRLVDGTHKLAAGDFTTRVTPTSE 217 RQ + L+ A L AL L+A V+ V H LA + P S Sbjct: 75 RQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD---AMKCFPGSF 131 Query: 218 DEL-----------GKLAQDFNQLASTLEKNQQMR 241 + L G L N+LA E+ QQMR Sbjct: 132 ERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMR 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 6e-18 Identities = 28/136 (20%), Positives = 65/136 (47%), Gaps = 1/136 (0%) Query: 11 PRILIVEDEPKLGQLLIDYLRAASYAPTLISHGDQVLPYVRQTPPDLILLDLMLPGTDGL 70 IL+ +D+ + +L L A Y + S+ + ++ DL++ D+++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 TLCREIR-RFSDIPIVMVTAKIEEIDRLLGLEIGADDYICKPYSPREVVARVKTILRRCK 129 L I+ D+P+++++A+ + + E GA DY+ KP+ E++ + L K Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 130 PQRELQQQDAESPLII 145 + + D++ + + Sbjct: 124 RRPSKLEDDSQDGMPL 139
>PF09025#YopR Core Length = 143 Score = 28.8 bits (64), Expect = 0.038 Identities = 28/102 (27%), Positives = 40/102 (39%), Gaps = 6/102 (5%) Query: 374 WPRSEQENSPAATRRLFSFQAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDA 433 + ++ PAA RRL + GAL + A L + L + +PL Sbjct: 32 FEQALGGEPPAAGRRLAGLENGALGERLLQRFAQPLQGLEADRLELKAMLRAELPLGRQQ 91 Query: 434 ----WQMLSAPLRQPGIVALREYLRQRPPACIRPLN-QVDNL 470 Q+L A PG L + R+ I PLN +DNL Sbjct: 92 QTFLLQLLGAVEHAPGGEYLAQLARRELQVLI-PLNGMLDNL 132
>INTIMIN#Intimin signature. Length = 939 Score = 27.3 bits (60), Expect = 0.028 Identities = 19/94 (20%), Positives = 31/94 (32%) Query: 36 LNGTEIAITYVYKGDKVLKQSSETKIQFASIGATTKEDAAKTLEPLSAKYKNIAGVEEKL 95 + + AITY K K K S ++ F + KT AK + K Sbjct: 671 VANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKS 730 Query: 96 TYTDTYAQENVTIDMEKVDFKALQGISGINVSAE 129 + + V + +V+F I N+ Sbjct: 731 LVSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIV 764
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.4 bits (175), Expect = 1e-16 Identities = 41/177 (23%), Positives = 77/177 (43%), Gaps = 12/177 (6%) Query: 2 IKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVHKLRPDVLFLDIQMPRIS 61 +L+ DD+ R L L ++ ++ SNA + D++ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GLEMVGMLDPEHRPYI--VFLTAFD--EYAIKAFEEHAFDYLLKPIDEARLEKTLARLRQ 117 +++ + + RP + + ++A + AIKA E+ A+DYL KP D L + R Sbjct: 62 AFDLLPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 118 ERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRMSGVYVT--SHEGKE 172 E ++ L ++Q + + G S + +A + + +T S GKE Sbjct: 121 EPKRRPSKLEDDSQDGMPLV---GRSAAMQEIYRVLARLMQTDLTLMITGESGTGKE 174
>PF06580#Sensor histidine kinase Length = 349 Score = 220 bits (562), Expect = 4e-69 Identities = 63/216 (29%), Positives = 115/216 (53%), Gaps = 3/216 (1%) Query: 343 LGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIKAVIRRDSEQA 402 L G + + + +M ++++ L AQ+NPHF+FNALN I+A+I D +A Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKA 193 Query: 403 SQLVQYLSTFFRKNLKR-PSEFVTLADEIEHVNAYLQIEKARFQSRLQVNIAIPQELSQQ 461 +++ LS R +L+ + V+LADE+ V++YLQ+ +F+ RLQ I + Sbjct: 194 REMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDV 253 Query: 462 QLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNAGL-YQPVTNASGL 520 Q+P +Q +VEN IKHG +QL G++ + ++ + LE+E+ L + ++G Sbjct: 254 QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGT 313 Query: 521 GMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLP 556 G+ V +RL+ +G + I ++ + + +P Sbjct: 314 GLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 43.6 bits (103), Expect = 5e-07 Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 18/195 (9%) Query: 1 MPKFRVSLFSLALMLAVPFAPQAVAKTAAATTASQPEIASGSAMI-VDLNTNKVIYSNHP 59 M R+ + SL + +P A A + S+ +++ MI +DL + + + + Sbjct: 1 MRYIRLCIISL--LATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRA 58 Query: 60 DLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVYSRV---RLNSEISRKDM 116 D P+ S K++ VL DE+L+ I + YS V L ++ ++ Sbjct: 59 DERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGEL 118 Query: 117 LLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTRFV--EPTGLS-----V 169 A+ S+N +AA+L GG + A + +G N TR E Sbjct: 119 CAAAITMSDN-SAANLLLATVGG----PAGLTAFLRQIGDNVTRLDRWETELNEALPGDA 173 Query: 170 HNVSTARDLTKLLIA 184 + +T + L Sbjct: 174 RDTTTPASMAATLRK 188
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 28.3 bits (63), Expect = 0.019 Identities = 5/33 (15%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 152 WLHNLDQHLKHW-VWLILVVVL-VVGVRWWLKR 182 L + ++ + W++L ++ + R L++ Sbjct: 215 VLMGMSDAVRTFGPWMLLALLAGFMAFRVMLRQ 247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (284), Expect = 1e-32 Identities = 71/253 (28%), Positives = 116/253 (45%), Gaps = 12/253 (4%) Query: 3 QVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTAREVVSHGVRAEIVQLDLG 62 ++A IT + GIG+ A LA QG I ++ E+ K + AE D+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKA-EARHAEAFPADVR 67 Query: 63 NLPEGALALEKLIQRLGRIDVLVNNAGAMTKAPFLDMAFDEWRKIFTVDVDGAFLCSQIA 122 + ++ + +G ID+LVN AG + ++ +EW F+V+ G F S+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 ARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHALGGLTKAMALELVRHKILVNAVA 182 ++ M+ + + G I+ + S P +AY ++K A TK + LEL + I N V+ Sbjct: 128 SKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGAIATPM-------NGMDDSDVKPDAEP---SIPLRRFGATHEIASLVVWLCSEGANYT 232 PG+ T M + +K E IPL++ +IA V++L S A + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 233 TGQSLIVDGGFML 245 T +L VDGG L Sbjct: 247 TMHNLCVDGGATL 259
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 28.2 bits (63), Expect = 0.044 Identities = 31/127 (24%), Positives = 53/127 (41%), Gaps = 5/127 (3%) Query: 122 GAKAMREAVPAHLPVSVKVRLGWDSGEK-KFEIADAVQQAGATELVVHGRTKEQGY-RAE 179 G EA+ ++ + +G + E+ K EI A E+ V GR +G R Sbjct: 190 GGDRFDEAIINYVRRNYGSLIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGF 249 Query: 180 HIDWQAIGD-IRQRLNIPVIANGEIWDWQSAQQCMAISGCDAVMIGRGALNIPNLSRVVK 238 ++ I + +++ L V A + + IS V+ G GAL + NL R++ Sbjct: 250 TLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGAL-LRNLDRLL- 307 Query: 239 YNEPRMP 245 E +P Sbjct: 308 MEETGIP 314
>ECOLIPORIN#E.coli/Salmonella-type porin signature. Length = 383 Score = 536 bits (1381), Expect = 0.0 Identities = 252/383 (65%), Positives = 292/383 (76%), Gaps = 16/383 (4%) Query: 1 MKVKVLSLLVPALLVAGAANAAEVYNKDGNKLDLYGKVDGLHYFSDNKDVDGDQTYMRLG 60 MK KVL+L++PALL AGAA+AAE+YNKDGNKLDLYGKVDGLHYFSD+ DGDQTYMR+G Sbjct: 1 MKRKVLALVIPALLAAGAAHAAEIYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVG 60 Query: 61 FKGETQVTDQLTGYGQWEYQIQGNSAENE-NNSWTRVAFAGLKFQDVGSFDYGRNYGVVY 119 FKGETQ+ DQLTGYGQWEY +Q N+ E E NSWTR+AFAGLKF D GSFDYGRNYGV+Y Sbjct: 61 FKGETQINDQLTGYGQWEYNVQANTTEGEGANSWTRLAFAGLKFGDYGSFDYGRNYGVLY 120 Query: 120 DVTSWTDVLPEFGGDTYG-SDNFMQQRGNGFATYRNTDFFGLVDGLNFAVQYQGKNGNPS 178 DV WTD+LPEFGGD+Y +DN+M R NG ATYRNTDFFGLVDGLNFA+QYQGKN + S Sbjct: 121 DVEGWTDMLPEFGGDSYTYADNYMTGRANGVATYRNTDFFGLVDGLNFALQYQGKNESQS 180 Query: 179 GEGFTSGV--TNNGRDALRQNGDGVGGSITYDY-EGFGIGGAISSSKRTDAQN-TAAYIG 234 + G NNG D NGDG G S TYD GF G A ++S RT+ Q I Sbjct: 181 ADDVNIGTNNRNNGDDIRYDNGDGFGISTTYDIGMGFSAGAAYTTSDRTNEQVNAGGTIA 240 Query: 235 NGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSL------GWANKAQNFEAVAQYQF 288 GD+A+ +T GLKYDANNIYLA Y++T N T G G ANK QNFE AQYQF Sbjct: 241 GGDKADAWTAGLKYDANNIYLATMYSETRNMTPYGKTDKGYDGGVANKTQNFEVTAQYQF 300 Query: 289 DFGLRPSLAYLQSKGKNLGR---GYDDEDILKYVDVGATYYFNKNMSTYVDYKINLLD-D 344 DFGLRP++++L SKGK+L DD+D++KY DVGATYYFNKN STYVDYKINLLD D Sbjct: 301 DFGLRPAVSFLMSKGKDLTYNNVNGDDKDLVKYADVGATYYFNKNFSTYVDYKINLLDDD 360 Query: 345 NQFTRDAGINTDNIVALGLVYQF 367 + F +DAGI+TD+IVALG+VYQF Sbjct: 361 DPFYKDAGISTDDIVALGMVYQF 383
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 47.9 bits (114), Expect = 9e-09 Identities = 26/145 (17%), Positives = 60/145 (41%), Gaps = 20/145 (13%) Query: 1 MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINNLPKLDAHVLITDLSMP 60 M +++ADD + + ++L + + + ++ L + D +++TD+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLDIEGIVLKQGA------PT 114 + L+ IK+ P L ++V++ N +A+ ++GA P Sbjct: 59 D---ENAFDLLPRIKKARPDLPVLVMSAQNTFM--TAIKA-------SEKGAYDYLPKPF 106 Query: 115 DLPKALAALQKGKKFTPESVSRLLE 139 DL + + + + S+L + Sbjct: 107 DLTELIGIIGRALAEPKRRPSKLED 131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.2 bits (203), Expect = 3e-18 Identities = 29/106 (27%), Positives = 48/106 (45%) Query: 827 ILVVDDHPINRRLLADQLGSLGYQCKTANDGVDALNVLSKNHIDIVLSDVNMPNMDGYRL 886 ILV DD R +L L GY + ++ ++ D+V++DV MP+ + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 887 TQRIRQLGLTLPVIGVTANALAEEKQRCLESGMDSCLSKPVTLDVI 932 RI++ LPV+ ++A + E G L KP L + Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTEL 111
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 563 bits (1452), Expect = 0.0 Identities = 181/484 (37%), Positives = 270/484 (55%), Gaps = 35/484 (7%) Query: 1 MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLFADIHPDVVLMDIRMPE 60 MT IL+ DD+ +R +L+ A + G++ +N T A D+V+ D+ MP+ Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 61 MDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDYVIKPFDLDELNLIVQRAL 120 + L ++ PV++M+A TA++A GA+DY+ KPFDL EL I+ RAL Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 121 QLQSMKKEIRHLHQALSTSWQWGH-ILTNSPAMMDICKDTAKIALSQASVLISGESGTGK 179 + L Q G ++ S AM +I + A++ + +++I+GESGTGK Sbjct: 120 AEP------KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGK 173 Query: 180 ELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHEKGAFTGAQTLRQGLFERANEG 239 EL+ARA+H +R GPF+ +N AA+P L+ESELFGHEKGAFTGAQT G FE+A G Sbjct: 174 ELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGG 233 Query: 240 TLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIKVDIRIIAATNRDLQAMVKEGTFR 299 TL LDEIG+MP+ Q +LLR+LQ+ E+ +GG I+ D+RI+AATN+DL+ + +G FR Sbjct: 234 TLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFR 293 Query: 300 EDLFYRLNVIHLILPPLRDRREDISLLANHFLQKFSSENQRDIIDIDPMAMSLLTAWSWP 359 EDL+YRLNV+ L LPPLRDR EDI L HF+Q+ E + D A+ L+ A WP Sbjct: 294 EDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWP 352 Query: 360 GNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQPV---------CNAGEVKTAPVGERN- 409 GN+REL N++ R + +I E + ++R + +G + + E N Sbjct: 353 GNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENM 412 Query: 410 ----------------LKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYKLQE 453 + +E +I+ L GN+ + A +LG++R L K++E Sbjct: 413 RQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472 Query: 454 YGID 457 G+ Sbjct: 473 LGVS 476
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 36.2 bits (83), Expect = 2e-05 Identities = 37/171 (21%), Positives = 72/171 (42%), Gaps = 25/171 (14%) Query: 5 FLTLLCVSSAIAHAADEDITFHGTLLSPPTCSISGGKTIEVEFRDLIIDDINGNYGRKEV 64 F++LL S A+ AD I G + PP C+I+ G+ I V+F ++ + ++ + G Sbjct: 7 FISLLLTSVAVL--ADVQINIRGNVYIPP-CTINNGQNIVVDFGNINPEHVDNSRGEVTK 63 Query: 65 PYELTCDSTTRHPDWEMTLTWTG-TQTSFNDAAIETDVPGFGIELQH------------- 110 ++C + + + TG T + + T++ FGI L Sbjct: 64 NISISCP----YKSGSLWIKVTGNTMGVGQNNVLATNITHFGIALYQGKGMSTPLTLGNG 119 Query: 111 DGQRFKLNTPLAINATDFTQKPKLEAVPVKASDAVLSDTNFSAYATLRVDY 161 G +++ L + FT +VP + +L+ +F A++ + Y Sbjct: 120 SGNGYRVTAGLDTARSTFT----FTSVPFRNGSGILNGGDFRTTASMSMIY 166
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 39.3 bits (91), Expect = 2e-06 Identities = 33/136 (24%), Positives = 62/136 (45%), Gaps = 12/136 (8%) Query: 45 PPCSIKGSQ---VEFGNMIADNVDGTNYRQDAKYTLNCTNSLANDLRMQLKGNTSTINGE 101 PPC+I Q V+FGN+ ++VD + +++C + L +++ GNT + Sbjct: 32 PPCTINNGQNIVVDFGNINPEHVDNSRGEVTKNISISCPYK-SGSLWIKVTGNTMGVGQN 90 Query: 102 TVLSTNITGLGIRI-ENSADNSLFAVGENSWTPFNIN-------NQPQLKAVPVKASGAQ 153 VL+TNIT GI + + ++ +G S + + + +VP + Sbjct: 91 NVLATNITHFGIALYQGKGMSTPLTLGNGSGNGYRVTAGLDTARSTFTFTSVPFRNGSGI 150 Query: 154 LAAGEFNASLTMVVDY 169 L G+F + +M + Y Sbjct: 151 LNGGDFRTTASMSMIY 166
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 208 bits (531), Expect = 2e-63 Identities = 66/268 (24%), Positives = 111/268 (41%), Gaps = 17/268 (6%) Query: 6 NSTVSYNGNYGS-GTDSSQVGYFSRV--DDATHYQLNIGTSDK-----HTSVDGYYSHDG 57 +++ SY+ ++ G ++ G + + D+ Y + G + ++ ++ G Sbjct: 616 HASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRG 675 Query: 58 SLAQVDLSANYHEGQYTSAGLSLQGGATLTTHGGALHRTQNMGGTRLLIDADGVADVPVE 117 ++ H + GG +G L Q + T +L+ A G D VE Sbjct: 676 GYGNANIGY-SHSDDIKQLYYGVSGGVLAHANGVTLG--QPLNDTVVLVKAPGAKDAKVE 732 Query: 118 GNGAAVYTNMFGKAVVSDVNNYYRNQAYIDLNKLPENAEATQSVVQATLTEGAIGYRKFA 177 N V T+ G AV+ Y N+ +D N L +N + +V T GAI +F Sbjct: 733 -NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFK 791 Query: 178 VISGQKAMAVLRLQDGSHPPFGAEVKNDNEQTVGLVDDDGSVYLAGVKPGEHMSVFW--S 235 G K + L + PFGA V +++ Q+ G+V D+G VYL+G+ + V W Sbjct: 792 ARVGIKLLMTLT-HNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEE 850 Query: 236 GVAHC--DINLPDPLPADLFNGLLLPCQ 261 AHC + LP L L C+ Sbjct: 851 ENAHCVANYQLPPESQQQLLTQLSAECR 878
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 539 bits (1389), Expect = 0.0 Identities = 149/596 (25%), Positives = 262/596 (43%), Gaps = 42/596 (7%) Query: 5 SLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKY 64 RL + +A + + + + ++ F+ RFL DL RF + + PG Y Sbjct: 19 RKHRLAGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTY 78 Query: 65 NLQVQLNKQPLAEEYDIYWYAGEDDVSKSYACLTPELVAQFGLKEDVAKNLQWSHDGKCL 124 + + LN +A D+ + D CLT +A GL + D C+ Sbjct: 79 RVDIYLNNGYMAT-RDVTFNT-GDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACV 136 Query: 125 KPGQL-EGVEIKADLSQSALVISLPQAYLEYTWPDWDPPSRWDDGISGIIADYSITAQTR 183 + + D+ Q L +++PQA++ + PP WD GI+ + +Y+ + + Sbjct: 137 PLTSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSV 196 Query: 184 HEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNYQHTRSNDDDDEFGGDDTQKKWEWSR 243 GG+ S+ N G+N+G WR+R + +Y + S+ + KW+ Sbjct: 197 QNRIGGN-SHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGS--------KNKWQHIN 247 Query: 244 YYAWRALPSLKAKLALGEDYLNSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHT 303 + R + L+++L LG+ Y DIFDG N+ G +++DD MLP + RG+AP I G+A Sbjct: 248 TWLERDIIPLRSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARG 307 Query: 304 TAKVTVSQMGRVIYETQVPAGPFRIQDL-GDSVSGTLHIRIEEQNGQVQEYDISTASMPY 362 TA+VT+ Q G IY + VP GPF I D+ SG L + I+E +G Q + + +S+P Sbjct: 308 TAQVTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPL 367 Query: 363 LTRPGQVRYKIMMGRPQEWGHHVEGGFFSGAEASWGIANGWSLYGGALGDENYQSAALGV 422 L R G RY I G + E F + G+ GW++YGG + Y++ G+ Sbjct: 368 LQREGHTRYSITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGI 427 Query: 423 GRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYRFS 482 G+++ GA++ D+T +++ L D DG S R Y+K ++ + + GYR+S Sbjct: 428 GKNMGALGALSVDMTQANSTLPDD-----SQHDGQSVRFLYNKSLNESGTNIQLVGYRYS 482 Query: 483 EENFMTMSEYLDASDSEMVRTGND-------------------KEMYTATYNQNFRDAGV 523 + ++ + + D + T Q Sbjct: 483 TSGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTS- 541 Query: 524 SVYLNYTRHTYWD-REEQTNYNIMLSHYFNMGSIRNMSVSLTGYRYEYDNRADKGM 578 ++YL+ + TYW + L+ F + ++S + + + D+ + Sbjct: 542 TLYLSGSHQTYWGTSNVDEQFQAGLNTAFEDIN---WTLSYSLTKNAWQKGRDQML 594
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 34.5 bits (79), Expect = 8e-04 Identities = 45/314 (14%), Positives = 112/314 (35%), Gaps = 36/314 (11%) Query: 69 LGSLVLGWISDHIGRQKIFTFSFLLITLASFLQFFATTP-EHLIGLRILIGIGLGGDYSV 127 +G+ V G +SD +G +++ F ++ S + F + LI R + G G ++ Sbjct: 64 IGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPAL 123 Query: 128 GHTLLAEFSPRRHRGILLGAFSVVWT----VGYVLASIAGHHFISENPEAWRWLLASAAL 183 ++A + P+ +RG G + VG + + H+ W +LL + Sbjct: 124 VMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI------HWSYLLLIPMI 177 Query: 184 PALLITLLRWGTPESPRWLLRQGRFAEAHAIVHRYFGPHVLLGDEVVTATHKHIKTLF-- 241 + + L + R +G F I+ +L + + + L Sbjct: 178 TIITVPFLMKLLKKEVR---IKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFL 234 Query: 242 -SSRYWRRTA--------FNSVFFVCLVIPWFVIYT----WLPTIAQTIGLEDALTASLM 288 ++ R+ ++ F+ V+ +I+ ++ + + L+ + + Sbjct: 235 IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEI 294 Query: 289 LNALLIVGALLGLV-------LTHLLAHRKFLLGSFLLLAATLVVMACLPSGSSLTLLLF 341 + ++ G + ++ L L L+ + + + L +S + + Sbjct: 295 GSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTII 354 Query: 342 VLFSTTISAVSNLV 355 ++F + + V Sbjct: 355 IVFVLGGLSFTKTV 368
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 102 bits (255), Expect = 4e-28 Identities = 73/257 (28%), Positives = 116/257 (45%), Gaps = 11/257 (4%) Query: 11 MDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGANIFIPSFVKDNGETKEMIEK-QGVEVD 69 M+ ++GK A +TG G+G+A A LA GA+I + + E K + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 70 FMQVGITAEGAPQKIIAACCERFGTVDILVNNAGICKLNKVLDFGRADWDPMIDVNLTAA 129 + A +I A G +DILVN AG+ + + +W+ VN T Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 130 FELSYEAAKIMIPQKSGKIINICSLFSYLGGQWSPAYSATKHALAGFTKAYCDELGQYNI 189 F S +K M+ ++SG I+ + S + + AY+++K A FTK EL +YNI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 190 QVNGIAPGYYATDI--TLATRSNPETNQRVLDH-------IPANRWGDTQDLMGAAVFLA 240 + N ++PG TD+ +L N Q + IP + D+ A +FL Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAE-QVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 241 SPASNYVNGHLLVVDGG 257 S + ++ H L VDGG Sbjct: 240 SGQAGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.018 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 8/103 (7%) Query: 48 GLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVMLCIQIA 107 G++++ + + G ++D+F R ++ ++ + +MAT P LWV+ +I Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 108 FAITTILMLWSVSIKAASLLGD---HSEQGKIMGWMEGLRGVG 147 IT + A + + D E+ + G+M G G Sbjct: 106 AGITG-----ATGAVAGAYIADITDGDERARHFGFMSACFGFG 143
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 29.3 bits (65), Expect = 0.038 Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 9/132 (6%) Query: 211 GYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLA-----GEGN 265 P L N + A+ +E K YE+GK I+L + + ++ + + Sbjct: 147 RETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSDSS 206 Query: 266 KAFTSEEFTHFLEELTKQYPIVSIEDGLDESDW---DGFAYQTKVLG-DKIQLVGDDLFV 321 S++F LE K I I++ L E F+Y ++L D+F Sbjct: 207 DLLFSQKFKEKLELNNKSIDINFIKENLTEFQHAFSLAFSYYFAPDHRTVLELYAPDMFE 266 Query: 322 TNTKILKEGIEK 333 K+ K G EK Sbjct: 267 YMNKLEKGGFEK 278
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 773 bits (1998), Expect = 0.0 Identities = 317/849 (37%), Positives = 469/849 (55%), Gaps = 48/849 (5%) Query: 31 SGMLCTTANAEEYYFDPIMLETTKSGMQTTDLSRFSKKYAQLPGTYQVDIWLNKKKVSQK 90 + ++ E YF+P L DLSRF PGTY+VDI+LN ++ + Sbjct: 35 AFAAQAPLSSAELYFNPRFLAD--DPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATR 92 Query: 91 KITFTAN-AEQLLQPQFTVEQLRELGIKVDEIPALAEKDDDSVINSLEQIIPGTAAEFDF 149 +TF +EQ + P T QL +G+ + + DD+ + L +I A+ D Sbjct: 93 DVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVP-LTSMIHDATAQLDV 151 Query: 150 NHQQLNLSIPQIALYRDARGYVSPSRWDDGIPTLFTNYSFTGSDNRYRQGNRSQRQYLNM 209 Q+LNL+IPQ + ARGY+ P WD GI NY+F+G+ + R G S YLN+ Sbjct: 152 GQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNRIGGNSHYAYLNL 211 Query: 210 QNGANFGPWRLRNYSTWTRNDQTSS------WNTISSYLQRDIKALKSQLLLGESATSGS 263 Q+G N G WRLR+ +TW+ N SS W I+++L+RDI L+S+L LG+ T G Sbjct: 212 QSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYTQGD 271 Query: 264 IFSSYTFTGVQLASDDNMLPNSQRGFAPTVRGIANSSAIVTIRQNGYVIYQSNVSAGAFE 323 IF F G QLASDDNMLP+SQRGFAP + GIA +A VTI+QNGY IY S V G F Sbjct: 272 IFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPGPFT 331 Query: 324 INDLYPSSNSGDLEVTIEESDGTQRRFIQPYSSLPMMQRPGHLKYSATAGRYRADANSDS 383 IND+Y + NSGDL+VTI+E+DG+ + F PYSS+P++QR GH +YS TAG YR+ Sbjct: 332 INDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNAQQE 391 Query: 384 KEPEFAEATAIYGLNNTFTLYGGLLGSEDYYALGIGIGGTLGALGALSMDINRADTQFDN 443 K P F ++T ++GL +T+YGG ++ Y A GIG +GALGALS+D+ +A++ + Sbjct: 392 K-PRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTLPD 450 Query: 444 QHSFHGYQWRTQYIKDIPETNTNIAVSYYRYTNDGYFSFNEA------------------ 485 G R Y K + E+ TNI + YRY+ GYF+F + Sbjct: 451 DSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQDGVIQ 510 Query: 486 ----NTRNWDYNSRQKSEIQFNISQTIFDGVSLYASGSQQDYWGNNDKNRNISVGVSGQQ 541 T ++ ++ ++Q ++Q + +LY SGS Q YWG ++ + G++ Sbjct: 511 VKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAGLNTAF 570 Query: 542 WGVGYSLNYQYSRYTDQN-NDRALSLNLSIPLERWLPRSR--------VSYQMTSQKDRP 592 + ++L+Y ++ Q D+ L+LN++IP WL SY M+ + Sbjct: 571 EDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDSKSQWRHASASYSMSHDLNGR 630 Query: 593 TQHEMRLDGSLLDDGRLSYSLEQSLDDDNNHNS----SLNASYRSPYGTFSAGYSYGNDS 648 + + G+LL+D LSYS++ + NS +YR YG + GYS+ +D Sbjct: 631 MTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYGNANIGYSHSDDI 690 Query: 649 SQYNYGVTGGVVIHPHGVTLSQYLGNAFALIDANGASGVRIQNYPGIATDPFGYAVVPYL 708 Q YGV+GGV+ H +GVTL Q L + L+ A GA +++N G+ TD GYAV+PY Sbjct: 691 KQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVRTDWRGYAVLPYA 750 Query: 709 TTYQENRLSVDTTQLPDNVDLEQTTQFVVPNRGAMVAARFNANIGYRVLVTVSDRNGKPL 768 T Y+ENR+++DT L DNVDL+ VVP RGA+V A F A +G ++L+T+ N KPL Sbjct: 751 TEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKLLMTL-THNNKPL 809 Query: 769 PFGALASNDDTGQQSIVDEGGILYLSGISSKSQSWTVRWGNQADQQCQFAFSTPDSEPTT 828 PFGA+ +++ + IV + G +YLSG+ + V+WG + + C + P Sbjct: 810 PFGAMVTSESSQSSGIVADNGQVYLSGMPLAGK-VQVKWGEEENAHCVANYQLPPESQQQ 868 Query: 829 SVLQGTAQC 837 + Q +A+C Sbjct: 869 LLTQLSAEC 877
>FIMBRIALPAPF#Escherichia coli: P pili tip fibrillum papF protein signature. Length = 167 Score = 29.7 bits (66), Expect = 0.011 Identities = 42/160 (26%), Positives = 67/160 (41%), Gaps = 21/160 (13%) Query: 208 VKLSIQGNLTAPQSCKINQGDVIKVNFGFINGQKFTTRNAMPDGFTPVDFDITYDCGDTS 267 V+++I+GN+ P C IN G I V+FG IN + V +I+ C S Sbjct: 21 VQINIRGNVYIP-PCTINNGQNIVVDFGNINPEHVDNSRG------EVTKNISISCPYKS 73 Query: 268 KIKNSLQMRIDGTTGVVDQYNLVARRRSSDNVPDVGIRIENLGGGVANIPFQNG------ 321 SL +++ G T V Q N++A N+ GI + G + NG Sbjct: 74 ---GSLWIKVTGNTMGVGQNNVLA-----TNITHFGIALYQGKGMSTPLTLGNGSGNGYR 125 Query: 322 ILPVDPSGHGTVNMRAWPVNLVGGELETGKFQGTATITVI 361 + + T + P G L G F+ TA++++I Sbjct: 126 VTAGLDTARSTFTFTSVPFRNGSGILNGGDFRTTASMSMI 165
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 30.4 bits (68), Expect = 0.029 Identities = 11/72 (15%), Positives = 24/72 (33%), Gaps = 4/72 (5%) Query: 487 AGVNGGSGIALTGSPITLRATTDSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGE 546 + V+G + + + I + + ++ T D + G R A + + Sbjct: 330 SEVHGNAEVHASFFDIGGSVSAGFSNSNSS----TVAIDHSLSLAGERTWAETMGLNTAD 385 Query: 547 IAFIKPMIAMRN 558 A + I N Sbjct: 386 TARLNANIRYVN 397
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 27.6 bits (61), Expect = 0.036 Identities = 26/111 (23%), Positives = 44/111 (39%), Gaps = 22/111 (19%) Query: 42 NKILCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIA-------NDRL 94 K+L GN + A T + IA + V AI+ D+ Sbjct: 277 TKVL--GNVGKGISQYIIAQRAAQGLSTSAAAAGLIA----SAVTLAISPLSFLSIADKF 330 Query: 95 HD----EVYAKQVRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVA 141 E Y+++ + LG+ GD LLA + A++A++T T++A Sbjct: 331 KRANKIEEYSQRFKKLGYDGDSLLAAFHKETG-----AIDASLTTISTVLA 376
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 72.0 bits (176), Expect = 6e-16 Identities = 32/184 (17%), Positives = 63/184 (34%), Gaps = 38/184 (20%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQL------------NDGREFDAKLIGSDDQ 137 + SGV++ K +LTN HV++ L +G ++ + Sbjct: 102 FIASGVVVG--KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 138 SDIALLQIQN-------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALG 190 D+A+++ + ++++ + +V G P V+ + Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP-------VATMW 212 Query: 191 RSGLNLEGLEN-FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 S + L+ +Q D S GNSG + N E+IGI+ G+ Sbjct: 213 ESKGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFNGA 263 Query: 250 MART 253 + Sbjct: 264 VFIN 267
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 52.7 bits (126), Expect = 8e-10 Identities = 31/160 (19%), Positives = 59/160 (36%), Gaps = 26/160 (16%) Query: 77 RTLGSGVIMDQRGYIITNKHVINDADQIIVALQ------------DGRVFEALLVGSDSL 124 + SGV++ + ++TNKHV++ AL+ +G + Sbjct: 101 TFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGE 159 Query: 125 TDLAVLKI-------NATGGLPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATG 177 DLA++K + + ++ + + G P + T + G Sbjct: 160 GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKG 216 Query: 178 RIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINT 217 +I + +Q D S GNSG + N E++GI+ Sbjct: 217 KI---TYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHW 253
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.045 Identities = 37/167 (22%), Positives = 61/167 (36%), Gaps = 27/167 (16%) Query: 3 VAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSGED 62 + GAA GIG+A+A L G+ ++ D P V S A + F + Sbjct: 11 AFITGAAQGIGEAVARTL---ASQGAHIAAVDYNP-EKLEKVVSSLKAEARHAEAFPADV 66 Query: 63 ATPA------------LEGADVVLISAGVARK------PGMDRSDLFNVNAGIVKNLVQQ 104 A + D+++ AGV R + F+VN+ V N + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 105 VAKTCPK----ACIGIITNPVNTT-VAIAAEVLKKAGVYDKNKLFGV 146 V+K + + + +NP ++AA KA K G+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGL 173
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 169 bits (430), Expect = 4e-57 Identities = 44/141 (31%), Positives = 71/141 (50%), Gaps = 5/141 (3%) Query: 15 KALLKEEKFSSQGEIVAALQEQGFDNINQSKVSRMLTKFGAVRTRNAKMEMVYCLPAELG 74 + ++ + +Q E+V L++ G+ N+ Q+ VSR + + V+ Y LPA+ Sbjct: 11 REIITANEIETQDELVDILKKDGY-NVTQATVSRDIKELHLVKVPTNNGSYKYSLPADQR 69 Query: 75 VPTTSSPLKNLV---LDIDYNDAVVVIHTSPGAAQLIARLLDSLGKAEGILGTIAGDDTI 131 S ++L+ + ID ++V+ T PG AQ I L+D+L E I+GTI GDDTI Sbjct: 70 FNPLSKLKRSLMDAFVKIDSASHLIVLKTMPGNAQAIGALMDNLDWEE-IMGTICGDDTI 128 Query: 132 FTTPANGFTVKDLYEAILELF 152 K + + ILEL Sbjct: 129 LIICRTHDDTKVVQKKILELL 149
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.3 bits (128), Expect = 4e-10 Identities = 28/163 (17%), Positives = 59/163 (36%), Gaps = 16/163 (9%) Query: 6 RKFSRTAITVVLVILAFIAIFNAWVYYTE----SPWTRDARFSADVVAIAPDVSGLITQV 61 SR V I+ F+ I + + S I P + ++ ++ Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 62 NVHDNQLVKKGQILFTIDQPR-------YQKALEEAQADVAYYQVLAQEKRQEAGRRNRL 114 V + + V+KG +L + Q +L +A+ + YQ+L++ E + L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRS--IELNKLPEL 168 Query: 115 GVQAMSREEIDQANNVL---QTVLHQLAKAQATRDLAKLDLER 154 + + VL + Q + Q + +L+L++ Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDK 211 Score = 51.4 bits (123), Expect = 2e-09 Identities = 28/147 (19%), Positives = 54/147 (36%), Gaps = 15/147 (10%) Query: 100 LAQEKRQEAGRRNRLGVQ-AMSREEIDQANNVLQT-VLHQLAKAQAT-------RDLAKL 150 E R + ++ + ++EE + + +L +L + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEE 323 Query: 151 DLERTVIRAPADGWVTNLNVYT-GEFITRGSTAVALVKQNSFY-VLAYMEETKLEGVRPG 208 + +VIRAP V L V+T G +T T + +V ++ V A ++ + + G Sbjct: 324 RQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVG 383 Query: 209 YRAEIT----PLGSNKVLKGTVDSVAA 231 A I P L G V ++ Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINL 410
>DNABINDNGFIS#DNA-binding protein FIS signature. Length = 98 Score = 157 bits (399), Expect = 3e-54 Identities = 98/98 (100%), Positives = 98/98 (100%) Query: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ Sbjct: 1 MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNGQDVNDLYELVLAEVEQ 60 Query: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN Sbjct: 61 PLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 127 bits (321), Expect = 6e-39 Identities = 78/209 (37%), Positives = 122/209 (58%), Gaps = 3/209 (1%) Query: 1 MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVTRGAIYWHFENKTQLFN 60 MA++TK EA +TRQ +++ A+ F+Q GVS T+L +IA AA VTRGAIYWHF++K+ LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 EMW-LQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAKIPRQQALLKILYHKCEF 119 E+W L + ++ EL E A DP LRE LI L+ R++ L++I++HKCEF Sbjct: 61 EIWELSESNIGELELE-YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 120 NDEM-LAEGVIREKMGFNPQTLREVLQACQQQGCVANNLDLDVVMIIIDGAFSGIVQNWL 178 EM + + R + + + L+ C + + +L II+ G SG+++NWL Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 179 MNMAGYDLYKQAPALVDNVLRMFMPDENI 207 +DL K+A V +L M++ + Sbjct: 180 FAPQSFDLKKEARDYVAILLEMYLLCPTL 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.9 bits (101), Expect = 1e-06 Identities = 38/217 (17%), Positives = 70/217 (32%), Gaps = 38/217 (17%) Query: 98 ATYQANYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADA-RQADAAV 156 K +L + E+ A + Q + I D RQ + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLV----------TQLFKNEILDKLRQTTDNI 311 Query: 157 IAAKATVESARINLAYTKVTAPISGRIGK-STVTEGALVTNGQTTELATVQQLDPIYVDV 215 + + + AP+S ++ + TEG +VT +T + V + D + V Sbjct: 312 GLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTA 370 Query: 216 TQSSND--FMRLKQSVEQGNLHKENATSNVELVMENGQTYP-LKGTLQ--FSDVTVDEST 270 + D F+ + Q+ +++ Y L G ++ D D+ Sbjct: 371 LVQNKDIGFINVGQNAI------------IKVEAFPYTRYGYLVGKVKNINLDAIEDQRL 418 Query: 271 GSIT--LRAV------FPNPQHTLLPGMFVRARIDEG 299 G + + ++ N L GM V A I G Sbjct: 419 GLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTG 455 Score = 34.4 bits (79), Expect = 7e-04 Identities = 22/127 (17%), Positives = 43/127 (33%), Gaps = 13/127 (10%) Query: 46 TAPLEVKTELPGR-TNAYRIAEVRPQVSGIVLNRNFTEGSDVQAGQSLYQIDPATYQANY 104 +E+ G+ T++ R E++P + IV EG V+ G L ++ +A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEA-- 134 Query: 105 DSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAKATVE 164 + K++++ A L RY L E ++ + Sbjct: 135 -----DTLKTQSSLLQARLEQTRYQIL-----SRSIELNKLPELKLPDEPYFQNVSEEEV 184 Query: 165 SARINLA 171 +L Sbjct: 185 LRLTSLI 191 Score = 29.0 bits (65), Expect = 0.031 Identities = 11/34 (32%), Positives = 15/34 (44%), Gaps = 1/34 (2%) Query: 65 AEVRPQVSGIVLNRN-FTEGSDVQAGQSLYQIDP 97 + +R VS V TEG V ++L I P Sbjct: 328 SVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVP 361
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1406 bits (3642), Expect = 0.0 Identities = 1034/1034 (100%), Positives = 1034/1034 (100%) Query: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAM 840 Query: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV Sbjct: 841 ALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1021 VPVFFVVIRRCFKG 1034 VPVFFVVIRRCFKG Sbjct: 1021 VPVFFVVIRRCFKG 1034
>adhesinb#Adhesin B signature. Length = 310 Score = 27.5 bits (61), Expect = 0.004 Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 10/68 (14%) Query: 1 MKR---LIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTTQDNWETAGAIAGG 57 MK+ L+ + L LA C+ + +V TN+ + T++ IAG Sbjct: 1 MKKCRFLVLLLLAFVGLAACSSQKSSTETGSSKLNVVATNSIIADITKN-------IAGD 53 Query: 58 AAAVAGLT 65 + + Sbjct: 54 KINLHSIV 61
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 84.6 bits (209), Expect = 2e-21 Identities = 53/200 (26%), Positives = 95/200 (47%), Gaps = 15/200 (7%) Query: 59 DFSLAALWRNENHAGVKDANPVAVNQETPKLSIALNGIVLTSNDETSFVLINEGSEQKRY 118 DF+L + +N AG DA N L+++L G++ +D S +I++ +EQ Sbjct: 64 DFTLFGVSPEKNKAGALDA-SQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSR 122 Query: 119 SLNEALESAPGT--FIRKINKTSVVFETHGHYEKVTLH-------PGLP--DIIKQPDSE 167 +NE + PG I I VV + G YE + L+ G+P + +Q Sbjct: 123 GVNEEV---PGYNAKIVSIRPDRVVLQYQGRYEVLGLYSQEDSGSDGVPGAQVNEQLQQR 179 Query: 168 SQNVLADYIIATPIRDGEQIYGLRLNPRKGLNAFTTSLLQPGDIALRINNLSLTHPDEVS 227 + ++DY+ +PI + ++ G RLNP ++F LQ D+A+ +N L L ++ Sbjct: 180 ASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQAK 239 Query: 228 QALSLLLTQQSAQFTIRRNG 247 +A+ + + T+ R+G Sbjct: 240 KAMERMADVHNFTLTVERDG 259
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 719 bits (1856), Expect = 0.0 Identities = 348/630 (55%), Positives = 469/630 (74%), Gaps = 13/630 (2%) Query: 7 ITCCLLAALLMPCAGHAENEQYGANFNNADIRQFVEIVGQHLGKTILIDPSVQGTISVRS 66 +T + AALL A E++ A+F DI++F+ V ++L KT++IDPSV+GTI+VRS Sbjct: 12 LTLLIFAALLF---RPAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRS 68 Query: 67 NDTFSQQEYYQFFLSILDLYGYSVITLDNGFLKVVRSANVKTSPGMIADSSRPGVGDELV 126 D ++++YYQFFLS+LD+YG++VI ++NG LKVVRS + KT+ +A + PG+GDE+V Sbjct: 69 YDMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVV 128 Query: 127 TRIVPLENVPARDLAPLLRQMMDAGSVGNVVHYEPSNVLILTGRASTINKLIEVIKRVDV 186 TR+VPL NV ARDLAPLLRQ+ D VG+VVHYEPSNVL++TGRA+ I +L+ +++RVD Sbjct: 129 TRVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDN 188 Query: 187 IGTEKQQIIHLEYASAEDLAEILNQLISESHGKSQMPALLSAKIVADKRTNSLIISGPEK 246 G + L +ASA D+ +++ +L ++ KS +P + A +VAD+RTN++++SG Sbjct: 189 AGDRSVVTVPLSWASAADVVKLVTEL-NKDTSKSALPGSMVANVVADERTNAVLVSGEPN 247 Query: 247 ARQRITSLLKSLDVEESEEGNTRVYYLKYAKATNLVEVLTGVSEKLKDEKGNARKPSSSG 306 +RQRI +++K LD +++ +GNT+V YLKYAKA++LVEVLTG+S ++ EK A+ Sbjct: 248 SRQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAK---PVA 304 Query: 307 AMD-NVAITADEQTNSLVITADQSVQEKLATVIARLDIRRAQVLVEAIIVEVQDGNGLNL 365 A+D N+ I A QTN+L++TA V L VIA+LDIRR QVLVEAII EVQD +GLNL Sbjct: 305 ALDKNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNL 364 Query: 366 GVQWANKNVGAQQFTNTGLPIFNAAQGVADYKKNGGITSANPAWDMFSAYNGMAAGFFNG 425 G+QWANKN G QFTN+GLPI A G Y K+G ++S+ S++NG+AAGF+ G Sbjct: 365 GIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLA--SALSSFNGIAAGFYQG 422 Query: 426 DWGVLLTALASNNKNDILATPSIVTLDNKLASFNVGQDVPVLSGSQTTSGDNVFNTVERK 485 +W +LLTAL+S+ KNDILATPSIVTLDN A+FNVGQ+VPVL+GSQTTSGDN+FNTVERK Sbjct: 423 NWAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERK 482 Query: 486 TVGTKLKVTPQVNEGDAVLLEIEQEVSSVD---SSSNSTLGPTFNTRTIQNAVLVKTGET 542 TVG KLKV PQ+NEGD+VLLEIEQEVSSV SS++S LG TFNTRT+ NAVLV +GET Sbjct: 483 TVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGET 542 Query: 543 VVLGGLLDDFSKEQVSKVPLLGDIPLVGQLFRYTSTERAKRNLMVFIRPTIIRDDDVYRS 602 VV+GGLLD + KVPLLGDIP++G LFR TS + +KRNLM+FIRPT+IRD D YR Sbjct: 543 VVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQ 602 Query: 603 LSKEKYTRYRQEQQQRIDGKSKALVGSEDL 632 S +YT + Q ++ ++ + ++DL Sbjct: 603 ASSGQYTAFNDAQSKQRGKENNDAMLNQDL 632
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 517 bits (1332), Expect = 0.0 Identities = 195/405 (48%), Positives = 282/405 (69%), Gaps = 8/405 (1%) Query: 2 NYRYRAMTQDGQKLQGIIDANDERQARLRLREEGLFLLDIRPQK-------SSGVKTRRP 54 Y Y+A+ G+K +G +A+ RQAR LRE GL L + + S+G+ RR Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 55 -RISHSELTLFTRQLATLSAAALPLEESLAVIGQQSSNKRLGDVLNQVRSAILEGHPLSD 113 R+S S+L L TRQLATL AA++PLEE+L + +QS L ++ VRS ++EGH L+D Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 114 ALQHFPTLFDSLYRTLVKAGEKSGLLAPVLEKLADYNENRQKIRSKLIQSLIYPCMLTTV 173 A++ FP F+ LY +V AGE SG L VL +LADY E RQ++RS++ Q++IYPC+LT V Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 174 AIGVVIILLTAVVPKITEQFVHMKQQLPLSTRILLGLSDTLQRTGPTLLATVFIVAVGFW 233 AI VV ILL+ VVPK+ EQF+HMKQ LPLSTR+L+G+SD ++ GP +L + + F Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 234 LWLKRGNNRHRFHAMLLRVALIGPLICAINSARYLRTLSILQSSGVPLLDGMNLSTESLN 293 + L++ R FH LL + LIG + +N+ARY RTLSIL +S VPLL M +S + ++ Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 294 NLEIRQRLANAAENVRQGNSIHLSLEQTAIFPPMMLYMVASGEKSGQLGTLMVRAADNQE 353 N R RL+ A + VR+G S+H +LEQTA+FPPMM +M+ASGE+SG+L +++ RAADNQ+ Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 354 TLQQNRIALTLSIFEPALIITMALIVLFIVVSVLQPLLQLNSMIN 398 +++ L L +FEP L+++MA +VLFIV+++LQP+LQLN++++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLMS 407
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 250 bits (639), Expect = 3e-89 Identities = 145/145 (100%), Positives = 145/145 (100%) Query: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL Sbjct: 61 LDNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDL 120 Query: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145 LSAGPDGEMGTEDDITNWGLSKKKK Sbjct: 121 LSAGPDGEMGTEDDITNWGLSKKKK 145
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 146 bits (369), Expect = 2e-47 Identities = 51/156 (32%), Positives = 78/156 (50%), Gaps = 22/156 (14%) Query: 3 QQRGFTLLEMMLVLALVAITASVVLFTY--GREDVASTRARETAARFTAALELAIDRATL 60 +QRGFTLLEMML+L L+ ++A +VL + R+D A+ +T ARF A L R Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAA----QTLARFEAQLRFVQQRGLQ 57 Query: 61 SGQPVGIHFSDSAWRIMV----PGKTP-------SAWRWVPLQEDAADESQNDWDEELSI 109 +GQ G+ W+ +V G P S +RW+PL+ S + +L++ Sbjct: 58 TGQFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGRVATSGSIAGGKLNL 117 Query: 110 HL---QPFKPDDSNQPQVVILADGQITPFSLLMANA 142 + + P D P V+I G++TPF L + A Sbjct: 118 AFAQGEAWTPGD--NPDVLIFPGGEMTPFRLTLGEA 151
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.2 bits (68), Expect = 0.001 Identities = 17/90 (18%), Positives = 41/90 (45%), Gaps = 8/90 (8%) Query: 1 MNKQSGMTLLEVLLAMSIFTAVALTLMSSMQGQ--RNAIERMRNETLALWIADNQLQSQD 58 +KQ G TLLE+++ + I +A ++ ++ G + ++ ++ +AL A + + D Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK-LD 62 Query: 59 SFGEENTSSSGKELING-----EEWNWRSD 83 + T+ + L+ N+ + Sbjct: 63 NHHYPTTNQGLESLVEAPTLPPLAANYNKE 92
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.4 bits (76), Expect = 3e-04 Identities = 12/47 (25%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 4 RQQGFTLLEVMAALAIFSMLSVLAFMIFSQASELHQRSQKEIQQFNQ 50 RQ+GFTLLE+M L + + + + + F + + + + + +F Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRD--DSAAQTLARFEA 46
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 159 bits (404), Expect = 3e-50 Identities = 76/166 (45%), Positives = 98/166 (59%), Gaps = 2/166 (1%) Query: 55 VPLILCVAAAIACALAPFTPIVTGALFLYFCFVLTLSVIDFRTQLLPDKLTLPLLWLGLV 114 V L+ + + T A L ++ L+ ID LLPD+LTLPLLW GL+ Sbjct: 113 VELLTALLSVAVAMTLAPGWG-TLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLL 171 Query: 115 FNAQYGLIDLHDAVYGAVAGYGVLWCVYWGVWLVCHKEGLGYGDFKLLAAAGAWCGWQTL 174 FN G + L DAV GA+AGY VLW +YW L+ KEG+GYGDFKLLAA GAW GWQ L Sbjct: 172 FNLLGGFVSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQAL 231 Query: 175 PMILLIASLGGIGYAIVSQLLQRRTITT-IAFGPWLALGSMINLGY 219 P++LL++SL G I LL+ + I FGP+LA+ I L + Sbjct: 232 PIVLLLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLW 277
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 35.2 bits (81), Expect = 3e-05 Identities = 28/150 (18%), Positives = 59/150 (39%), Gaps = 24/150 (16%) Query: 5 TKVINYLNKLLGNE---LVAINQYFLHARMFKNWGLKRLNDVEYHESIDEM-----KHAD 56 T V N LN L N ++++ +W +K + HE +E+ + D Sbjct: 11 TLVENSLNTQLSNWFLLYSKLHRF--------HWYVKGPHFFTLHEKFEELYDHAAETVD 62 Query: 57 RYIERILFLEGLPN--LQDLGKL------NIGEDVEEMLRSDLALELDGAKNLREAIGYA 108 ER+L + G P +++ + EM+++ + + + IG A Sbjct: 63 TIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLA 122 Query: 109 DSVHDYVSRDMMIEILRDEEGHIDWLETEL 138 + D + D+ + ++ + E + L + L Sbjct: 123 EENQDNATADLFVGLIEEVEKQVWMLSSYL 152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 79.5 bits (196), Expect = 3e-18 Identities = 57/198 (28%), Positives = 87/198 (43%), Gaps = 13/198 (6%) Query: 13 VNVGTIGHVDHGKTTLTAAI------TTVLAKTYGGAARAFDQIDNAPEEKARGITINTS 66 +N+G + HVD GKTTLT ++ T L G R DN E+ RGITI T Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT----DNTLLERQRGITIQTG 59 Query: 67 HVEYDTPTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHILLGRQV 126 + +D PGH D++ + + +DGAIL+++A DG QTR R++ Sbjct: 60 ITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKM 119 Query: 127 GVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWE 186 G+P I F+NK D + L V +++E LS + + +W+ Sbjct: 120 GIP-TIFFINKIDQNGID--LSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 187 AKILELAGFLDSYIPEPE 204 I L+ Y+ Sbjct: 177 TVIEGNDDLLEKYMSGKS 194
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 613 bits (1583), Expect = 0.0 Identities = 178/698 (25%), Positives = 304/698 (43%), Gaps = 81/698 (11%) Query: 9 RYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAAT 68 + NIG+ AH+DAGKTT TE +L+ +G ++G V G D E++RGITI + T Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61 Query: 69 TAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERSMRVLDGAVMVYCAVGGVQPQSETVWR 128 + W ++NIIDTPGH+DF EV RS+ VLDGA+++ A GVQ Q+ ++ Sbjct: 62 SFQWEN-------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 129 QANKYKVPRIAFVNKMDRMGANFLKVVNQIKTRLGANPVPLQLAIGAEEHFTGVVDLVKM 188 K +P I F+NK+D+ G + V IK +L A V Q V M Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNM 164 Query: 189 KAINWNDADQGVTFEYEDIPADMVELANEWHQNLIESAAEASEELMEKYLGGEELTEAEI 248 N+ +++Q ++ E +++L+EKY+ G+ L E+ Sbjct: 165 CVTNFTESEQ------------------------WDTVIEGNDDLLEKYMSGKSLEALEL 200 Query: 249 KGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILDDGKDTPAE 308 + R N + V GSA N G+ +++ + + S Sbjct: 201 EQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVITNKFYSSTH----------------- 243 Query: 309 RHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHA 368 FKI L + R+YSGV++ D+V S K + + + Sbjct: 244 ---RGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEK-EKIKITEMYTSIN 299 Query: 369 NKREEIKEVRAGDIAAAIG----LKDVTTGDTLCDPDAPIILERMEFPEPVISIAVEPKT 424 + +I + +G+I L V GDT P ER+E P P++ VEP Sbjct: 300 GELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQR----ERIENPLPLLQTTVEPSK 354 Query: 425 KADQEKMGLALGRLAKEDPSFRVWTDEESNQTIIAGMGELHLDIIVDRMKREFNVEANVG 484 +E + AL ++ DP R + D +++ I++ +G++ +++ ++ +++VE + Sbjct: 355 PQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIK 414 Query: 485 KPQVAYRETIRQKVTDVEGKHAKQSGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGV 544 +P V Y E +K E + + + + + PL GS G ++ + + G Sbjct: 415 EPTVIYMERPLKK---AEYTIHIEVPPNPFWASIGLSVSPLPLGS---GMQYESSVSLGY 468 Query: 545 IPGEYIPAVDKGIQEQLKAGPLAGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEG 604 + + AV +GI+ + G L G+ V D I +G Y+ S+ F++ A I ++ Sbjct: 469 LNQSFQNAVMEGIRYGCEQG-LYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQV 527 Query: 605 FKKAKPVLLEPIMKVEVETPEENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMF 664 KKA LLEP + ++ P+E D + + + + V + E+P + Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587 Query: 665 GYATQLRSLTKGRASYTMEFLKYDEAPSNVAQAVIEAR 702 Y + L T GR+ E Y + V + R Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVT---TGEPVCQPR 622
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.021 Identities = 14/62 (22%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 ASSVEDLVTQTLEFTIEEVNADRNV-SNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI 218 A +V+D VTQ +E + ++ + S + + + L + D A QV ++L + Sbjct: 54 AQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQL 113 Query: 219 SK 220 + Sbjct: 114 AT 115
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 134 bits (339), Expect = 1e-40 Identities = 80/226 (35%), Positives = 125/226 (55%), Gaps = 9/226 (3%) Query: 28 AAKPATAADSKAAFKNDDQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAF 87 A A AA + D K +Y++GA LG K + GI ++ D L G+QD Sbjct: 14 AMSTAMAATDATSLTTDKDKLSYSIGADLG-------KNFKNQGIDINPDVLAKGMQDGM 66 Query: 88 A-DKSKLSDQEIEQTLQAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSST 146 + + L++++++ L F+ + + A+ K A +N+AKG + + G+ + Sbjct: 67 SGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIVVLPS 126 Query: 147 GLVYQVVEAGKGEAPKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGL 206 GL Y++++AG G P SDTV V Y GTLIDG FD++ G+P +F++ VIPGWTE L Sbjct: 127 GLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEAL 186 Query: 207 KNIKKGGKIKLVIPPELAYGKAGVPG-IPPNSTLVFDVELLDVKPA 251 + + G ++ +P +LAYG V G I PN TL+F + L+ VK A Sbjct: 187 QLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVKKA 232
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 30.7 bits (69), Expect = 0.021 Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 261 TAIDPFKGLLLG---LFFISVGMSLNLGVLYTHL-LWVVISVVVLVAVKILVLYLLARLY 316 A+ P L + L+FIS + L +++ + W +++ V+ ++ L Sbjct: 318 AAVAPHLDLTVDYGWLWFISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKA-- 375 Query: 317 GVRSSERMQ 325 S +M+ Sbjct: 376 QYTSMAKMR 384
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 31.9 bits (72), Expect = 0.001 Identities = 32/135 (23%), Positives = 51/135 (37%), Gaps = 16/135 (11%) Query: 12 YAHPESQDSVANRVLLKPATQLSNVTVHDLYAHYPDFFIDIPREQALLREHEVIVFQH-- 69 Y P + D N+V P + + +HD+ ++ D F L + + Sbjct: 9 YQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCV 68 Query: 70 ----PLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAGKYWRSVITTGEPESA------Y 119 P+ + P DR L F GPG N +G Y +IT PE + Sbjct: 69 QLGIPVVYTAQPGSQNP-DDRALLTDFW-GPGLN--SGPYEEKIITELAPEDDDLVLTKW 124 Query: 120 RYDALNRYPMSDVLR 134 RY A R + +++R Sbjct: 125 RYSAFKRTNLLEMMR 139
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 32.7 bits (74), Expect = 0.005 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 22/152 (14%) Query: 504 KVEPFDGDLEDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKE 563 + D + ++ E + + ++ R+ +R R + L E Sbjct: 272 AMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAE 331 Query: 564 IARLEKEME---------------------KLNAQLAQAEEKLGDSELYDQSRKAELTAC 602 +LE++ + +L A+ + EE+ SE QS + +L A Sbjct: 332 HQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDAS 391 Query: 603 LQQQASAKSGLEECEMAWLEAQEQLEQMLLEG 634 + + + LEE L A E+L + L E Sbjct: 392 REAKKQVEKALEEANSK-LAALEKLNKELEES 422 Score = 32.0 bits (72), Expect = 0.008 Identities = 13/125 (10%), Positives = 39/125 (31%), Gaps = 7/125 (5%) Query: 513 EDYQQWLSDVQKQENQTDEAPKENANSAQARKDQKRREAELRAQTQPLRKEIARLEKEME 572 + + ++ + E A A + D ++ + +++ Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFST-------ADSAKIK 179 Query: 573 KLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQEQLEQMLL 632 L A+ A E + + E + TA + + ++ + ++ LE + Sbjct: 180 TLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMN 239 Query: 633 EGQSN 637 ++ Sbjct: 240 FSTAD 244
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 31.8 bits (72), Expect = 0.002 Identities = 10/46 (21%), Positives = 21/46 (45%), Gaps = 2/46 (4%) Query: 71 PEANDFGLLEQTFIEYGQSGKGKSRKYLHTYDEAVPWNQVPGTFTP 116 P+ + + E ++ KG SRK++ ++ + + GTF Sbjct: 112 PDMEELDMKELSY--LSWIDKGSSRKFIIAKNDKNKFVGLQGTFQS 155
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.9 bits (101), Expect = 2e-06 Identities = 48/275 (17%), Positives = 94/275 (34%), Gaps = 32/275 (11%) Query: 44 PVSQVAFSFGLLSLGLAIS----SSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSDNL 99 + V +G+L A+ + V G L +RFG + V + S + + + A + L Sbjct: 37 HSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL 96 Query: 100 MMLWLS---AGVLVGLADGAGYLL----TLSNCVKWFPERKGLISAFAIGSYGLGSLGFK 152 +L++ AG+ AG + + F + LG Sbjct: 97 WVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGG---- 152 Query: 153 FIDTQLLETVGLEKTFVIWGAIALLMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMR 212 L+ F A+ L + G L+ ++ K E + R Sbjct: 153 -----LMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWAR 207 Query: 213 --KPQYWMLAVMFLTACMSG----LYVIGVAKDIAQSLAHLDVVSAANAVTVISIAN-LS 265 ++AV F+ + L+VI + H D + ++ I + L+ Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVI-----FGEDRFHWDATTIGISLAAFGILHSLA 262 Query: 266 GRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 ++ G ++ ++ R + +G + G L FA Sbjct: 263 QAMITGPVAARLGERRALMLGMIADGTGYILLAFA 297 Score = 36.3 bits (84), Expect = 2e-04 Identities = 37/155 (23%), Positives = 64/155 (41%), Gaps = 9/155 (5%) Query: 241 AQSLAHLDVVSAANAVTVISIANLSGRLVLGILSDKIARIRVITIGQVISLVGMAALLFA 300 AH ++ A A+ + A + G L SD+ R V+ + + V A + A Sbjct: 39 NDVTAHYGILLALYALMQFACAPVLGAL-----SDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 301 PLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFGLNNLAKNYGVIYLGFGIGSICGSIIA 360 P V + I VA G T V + +++ + A+++G + FG G + G ++ Sbjct: 94 PFLWVLYIGRI--VAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG 151 Query: 361 SLFGGF--YVTFYVIFALLILSLALSTTIRQPEQK 393 L GGF + F+ AL L+ + K Sbjct: 152 GLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHK 186
>ECOLNEIPORIN#E.coli/Neisseria porin superfamily signature. Length = 331 Score = 27.5 bits (61), Expect = 0.048 Identities = 19/90 (21%), Positives = 37/90 (41%), Gaps = 13/90 (14%) Query: 119 SMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQISYNQQFGENIWKAQSGLS 178 S+ + D+ + H S + + + R G++ P ++SY F + Sbjct: 228 SVAVQQQDAKLV-EENYSHNSQTEVAATLAYRFGNVTP--RVSYAHGFKGSF-------- 276 Query: 179 RMTATNQNGNWLDVTVGADMLLNQNIAAYA 208 ATN N ++ V VGA+ ++ +A Sbjct: 277 --DATNYNNDYDQVVVGAEYDFSKRTSALV 304
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 2e-05 Identities = 17/52 (32%), Positives = 26/52 (50%), Gaps = 5/52 (9%) Query: 76 VAPKAVRRGIGKALM----QYVQQRHP-HLMLEVYQKNQPAINFYQAQGFHI 122 VA ++G+G AL+ ++ ++ H LMLE N A +FY F I Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 113 bits (285), Expect = 2e-32 Identities = 41/122 (33%), Positives = 62/122 (50%), Gaps = 11/122 (9%) Query: 108 LNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEY--PKTAVNVIGYTDSTGGHDLNMRLS 165 + ++V F+ + ATLKP G L + L +V V+GYTD G N LS Sbjct: 215 FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLS 274 Query: 166 QQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGK---------AQNRRVEITL 216 ++RA SV LI++G+ A +I +G+G +NP+ N+ K A +RRVEI + Sbjct: 275 ERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV 334 Query: 217 SP 218 Sbjct: 335 KG 336
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 59.9 bits (145), Expect = 6e-12 Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 1/184 (0%) Query: 5 RNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGAVQSVMGAYLLTYGVSQLFYG 64 R+ +L+ L +L + + + ++ D+A D N + V A++LT+ + YG Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 65 PISDRVGRRPVILVGMSIFMLATLVA-VTTSSLTVLIAASAMQGMGTGVGGVMARTLPRD 123 +SD++G + ++L G+ I +++ V S ++LI A +QG G + + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 124 LYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWNWRACYLFLLVLCAGVTFSMARWM 183 + A L+ + + + P IGG++ +W L ++ V F M Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLK 190 Query: 184 PETR 187 E R Sbjct: 191 KEVR 194
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 120 bits (302), Expect = 2e-39 Identities = 50/89 (56%), Positives = 66/89 (74%) Query: 2 NKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQLVGFGTFKVNHRAERTGR 61 NK LI +AE EL+K + AA+++ +A++ L +G+ VQL+GFG F+V RA R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKEIKIAAANVPAFVSGKALKDAVK 90 NPQTG+EIKI A+ VPAF +GKALKDAVK Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>PF06580#Sensor histidine kinase Length = 349 Score = 37.5 bits (87), Expect = 9e-05 Identities = 49/262 (18%), Positives = 104/262 (39%), Gaps = 43/262 (16%) Query: 204 ILFALATVLLA-SVLSFFW-YRRYLRSRQLLQDEMKRKEKLVALGHLAAGV-AHEIRNPL 260 I+F + V S+L F W + + + ++ Q +M + L L A + H + N L Sbjct: 120 IIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL 179 Query: 261 SSIKGLAKYFAERAPAGGEAHQLAQVM---AKEADRLNRVVSELLELVKPTHLALQAVDL 317 ++I+ L +A L+++M + ++ +++ L +V ++L L ++ Sbjct: 180 NNIRALILEDPTKAREM--LTSLSELMRYSLRYSNARQVSLADELTVVD-SYLQLASIQF 236 Query: 318 NTLINHSLQLVSQDANSREIQLRFTANDTLPEIQADPDRLTQVLL-NLYLNAIQAIGQHG 376 + Q+ + ++Q+ P L Q L+ N + I + Q G Sbjct: 237 EDRLQFENQI---NPAIMDVQV--------------PPMLVQTLVENGIKHGIAQLPQGG 279 Query: 377 VISVTASESGAGVKISVTDSGKGIAADQLDAIFTPYFTTKAEGTGLGLAVVHNIVEQHGG 436 I + ++ V + V ++G + E TG GL V ++ G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNT------------KESTGTGLQNVRERLQMLYG 327 Query: 437 ---TIQVASQEGKGSTFTLWLP 455 I+++ ++GK + +P Sbjct: 328 TEAQIKLSEKQGKV-NAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 524 bits (1351), Expect = 0.0 Identities = 183/468 (39%), Positives = 253/468 (54%), Gaps = 35/468 (7%) Query: 8 ILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQVREQVFDLVLCDVRMAEMDGIAT 67 ILV DDD + T+L L GY+V + ++ + DLV+ DV M + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 68 LKEIKALNPAIPVLIMTAYSSVETAVEALKTGALDYLIKPLDFDNLQATLEKALAHTHSI 127 L IK P +PVL+M+A ++ TA++A + GA DYL KP D L + +ALA Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 128 DAETPAVTASQFGMVGKSPAMQHLLSEIALVAPSEATVLIHGDSGTGKELVARAIHASSA 187 ++ + +VG+S AMQ + +A + ++ T++I G+SGTGKELVARA+H Sbjct: 126 PSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGK 185 Query: 188 RSEKPLVTLNCAALNESLLESELFGHEKGAFTGADKRREGRFVEADGGTLFLDEIGDISP 247 R P V +N AA+ L+ESELFGHEKGAFTGA R GRF +A+GGTLFLDEIGD+ Sbjct: 186 RRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPM 245 Query: 248 MMQVRLLRAIQEREVQRVGSNQIISVDVRLIAATHRDLAAEVNAGRFRQDLYYRLNVVAI 307 Q RLLR +Q+ E VG I DVR++AAT++DL +N G FR+DLYYRLNVV + Sbjct: 246 DAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPL 305 Query: 308 EVPSLRQRREDIPLLAGHFLQRFAERNRKAVKGFTPQAMDLLIHYDWPGNIRELENAVER 367 +P LR R EDIP L HF+Q+ + VK F +A++L+ + WPGN+RELEN V R Sbjct: 306 RLPPLRDRAEDIPDLVRHFVQQAEKEGLD-VKRFDQEALELMKAHPWPGNVRELENLVRR 364 Query: 368 AVVLLTGEYISERELPLAIASTPIPLGQSQDIQP-------------------------- 401 L + I+ + + S + Sbjct: 365 LTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALP 424 Query: 402 --------LVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR 441 L E+E +ILAAL T GN+ +AA LG+ R TL K+ Sbjct: 425 PSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 31.3 bits (71), Expect = 7e-04 Identities = 23/62 (37%), Positives = 32/62 (51%), Gaps = 9/62 (14%) Query: 37 IANFFVAEKVLQDLVLQLHPRSTWHSFLPAKRMDIVVSALEMNEGGLSQVEERILHEVVA 96 IA+FFV EK+LQ + Q+H S P+ R+ + V G +QVE R + E Sbjct: 81 IADFFVTEKMLQHFIKQVHSNSF---MRPSPRVLVCVPV------GATQVERRAIRESAQ 131 Query: 97 GA 98 GA Sbjct: 132 GA 133
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.9 bits (80), Expect = 4e-05 Identities = 16/54 (29%), Positives = 21/54 (38%), Gaps = 5/54 (9%) Query: 78 IDPDVRGCGVGRVLVEHALSMAPE-----LTTNVNEQNEQAVGFYKKVGFKVTG 126 + D R GVG L+ A+ A E L + N A FY K F + Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150
>BINARYTOXINB#Binary toxin B family signature. Length = 764 Score = 32.3 bits (73), Expect = 0.004 Identities = 14/58 (24%), Positives = 23/58 (39%) Query: 289 ETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIASFQQQLSDMGYK 346 ET+ PD+ L A P L Y + N D +T + + QL+++ Sbjct: 544 ETTKPDMTLKEALKIAFGFNEPNGNLQYQGKDITEFDFNFDQQTSQNIKNQLAELNAT 601
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 30.4 bits (68), Expect = 0.007 Identities = 21/95 (22%), Positives = 38/95 (40%), Gaps = 3/95 (3%) Query: 20 AAGTVKVFSNGSSEAKTLTGAEHLIDLVGQPRLANSWWPGAVISEELATAAALRQQQALL 79 A + + + LT + L D+V + N+ + A AA++ + L Sbjct: 73 AKAAAEAQAKAKANRDALT--QRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERL 130 Query: 80 TRLAEQGADSSADDAAAINALRQQIQALKVTGRQK 114 RLA+ + + AA A ++ Q K R+K Sbjct: 131 -RLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREK 164
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 35.6 bits (82), Expect = 4e-04 Identities = 20/87 (22%), Positives = 42/87 (48%), Gaps = 3/87 (3%) Query: 279 VIGVMLSIFQQFVGINVVLYYAPEVFKTLGASTDIALLQTIIVGVINLTFTVLAIMT--- 335 +I ++ ++ VGI +++ P + + L S D+ I++ + L A + Sbjct: 7 LIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGAL 66 Query: 336 VDKFGRKPLQIIGALGMAIGMFSLGTA 362 D+FGR+P+ ++ G A+ + TA Sbjct: 67 SDRFGRRPVLLVSLAGAAVDYAIMATA 93
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 31.1 bits (70), Expect = 0.011 Identities = 22/124 (17%), Positives = 43/124 (34%), Gaps = 21/124 (16%) Query: 128 GDEWQLALSDGETGKNYLSDAFKFGGEQKLQLKETTAQPEGERANLRVITQNRQALSDIT 187 ++WQ+ T DA L+L T + L+ + A+ ++ Sbjct: 367 NNQWQVTRLASNTTFTVTPDANGKVAFDGLELTFTGTPAVNDSFTLKPV---SDAIVNMD 423 Query: 188 AILPDGNKVMMSSLRQFSGTQPLYTLDGDGTLTNNQSGVKYRPNNQ--------IGFYQS 239 ++ D K+ M+S GD N Q+ + + N++ Y S Sbjct: 424 VLITDEAKIAMAS----------EEDAGDSDNRNGQALLDLQSNSKTVGGAKSFNDAYAS 473 Query: 240 ITAD 243 + +D Sbjct: 474 LVSD 477
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.020 Identities = 12/22 (54%), Positives = 13/22 (59%) Query: 32 MVALLGPSGSGKSTLLRHLSGL 53 V L G G GKSTL+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGL 619
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 43.3 bits (102), Expect = 2e-06 Identities = 57/290 (19%), Positives = 105/290 (36%), Gaps = 55/290 (18%) Query: 85 FFGMLGDKYGRQKILAITIVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGE 144 G L D++GR+ +L +++ ++ + P +W +L I ++ G + G Sbjct: 62 VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF-----LW---VLYIGRIVAGIT-GAT 112 Query: 145 YTGASIFVAEYSPDRKR----GFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGW 200 A ++A+ + +R GFM + FG +AG VLG G++ S Sbjct: 113 GAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLG-GLMGGFSP------------ 159 Query: 201 RIPFFIALPLGIIGLYLRHALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRS 260 PFF A L + L K E+ P SF+ W Sbjct: 160 HAPFFAAAALNGLNFLTGCFLLPESH------KGERRPLRREALNPLASFR------WAR 207 Query: 261 LLTCIGLVIATNVTYYML----LTYMPSYLSHNLHYS-EDHGVLIIIAIMIGMLFVQPVM 315 +T + ++A ++ + H+ G+ + ++ L + Sbjct: 208 GMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMIT 267 Query: 316 GLLSDRFGRRPFVLLG----SVALFVLA--------IPAFILINSNVIGL 353 G ++ R G R ++LG +LA P +L+ S IG+ Sbjct: 268 GPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGM 317 Score = 39.0 bits (91), Expect = 4e-05 Identities = 39/164 (23%), Positives = 73/164 (44%), Gaps = 16/164 (9%) Query: 286 LSHNLHYSEDHGVLI-IIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVALFVLAIPAFI 344 L H+ + +G+L+ + A+M PV+G LSDRFGRRP +L+ L A+ I Sbjct: 35 LVHSNDVTAHYGILLALYALM--QFACAPVLGALSDRFGRRPVLLVS---LAGAAVDYAI 89 Query: 345 LINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIR---YSALAAAFNISVLVAG 401 + + + +++ G ++A I V + + + R + ++A F +VAG Sbjct: 90 MATAPFLWVLYIG-RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFG-MVAG 147 Query: 402 LTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITG-VTMKETANR 444 P L + S + P + + + +TG + E+ Sbjct: 148 --PVLGGLMGGFSPH--APFFAAAALNGLNFLTGCFLLPESHKG 187
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 8e-05 Identities = 40/182 (21%), Positives = 81/182 (44%), Gaps = 34/182 (18%) Query: 181 ARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLEDV-ILPSYDELSTML--DQRQQTLL 237 + +M+ S+S+L++ S N + V L +++ ++ SY +L+++ D+ Q Sbjct: 191 TKAREMLTSLSELMR-----YSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 238 LPESAADITVQGDATLLRMLLRNLVENAHRY----SPQGSNIMIKLQEDDGAV-MAVEDE 292 + + D+ V ML++ LVEN ++ PQG I++K +D+G V + VE+ Sbjct: 246 INPAIMDVQV------PPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 293 GPGIDESKCGELSKAFVRMDSRYGGIGLGLSIV-SRITQLHHGQFFLQNRQETSGTRAWV 351 G + + G GL V R+ L+ + ++ ++ A V Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMV 345 Query: 352 RL 353 + Sbjct: 346 LI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 1e-23 Identities = 41/121 (33%), Positives = 60/121 (49%) Query: 2 KILIVEDDTLLLQGLILAAQTEGYACDSVTTARMAEQSLEAGHYSLVVLDLGLPDEDGLH 61 IL+ +DD + L A GY + A + + AG LVV D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 FLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKPFALEELHARIRALLRRHNN 121 L RI++ + LPVL+++A++T I + GA DYL KPF L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 Q 122 + Sbjct: 125 R 125
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.2 bits (73), Expect = 5e-04 Identities = 15/48 (31%), Positives = 18/48 (37%) Query: 97 PAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGF 144 R KG+ L A+E A+E F LET A Y F Sbjct: 99 KDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 29.2 bits (65), Expect = 0.014 Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 4/45 (8%) Query: 145 PLLVSHGIALGCLVSTILGLPAWAERRLRLRNCSISRVDYQESLW 189 P +V GIA G V T+ GL W ++ N D + +W Sbjct: 42 PAIVG-GIATGAAVGTVSGLLGWGLKQAEEAN---KTPDKPDKVW 82
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 7e-22 Identities = 33/139 (23%), Positives = 60/139 (43%) Query: 1 MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKARKQVPDVMILDVGLPDI 60 M T+ + +D+ I L L + G+ V + + D+++ DV +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYVAKPFSPREVCARVRTLLR 120 + F+L ++ P LPVL ++A++ + + E GA DY+ KPF E+ + L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 RVKKFSTPSPVIRIGHFEL 139 K+ + L Sbjct: 121 EPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.002 Identities = 47/207 (22%), Positives = 77/207 (37%), Gaps = 51/207 (24%) Query: 298 LTQNARMQAL---------VETL--LRQARLENRQEVVLTAVDVAALFR---RVSEARTV 343 + Q A++ AL L +R LE+ + ++ L R R S AR V Sbjct: 157 MAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQV 216 Query: 344 QLAE-----------------KKITLHV-TPTEVNVAAEPALLEQAL-GNLLDNAIDFTP 384 LA+ ++ + P +L Q L N + + I P Sbjct: 217 SLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLP 276 Query: 385 ESGCITLSAEVDQEHVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSE 444 + G I L D VTL+V +TGS N ++S+G GL V E Sbjct: 277 QGGKILLKGTKDNGTVTLEVENTGSLALK----------------NTKESTGTGLQNVRE 320 Query: 445 -VARLFNGEVTLR-NVQEGGVLASLRL 469 + L+ E ++ + ++G V A + + Sbjct: 321 RLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 30/122 (24%), Positives = 60/122 (49%), Gaps = 1/122 (0%) Query: 1 MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILSEYDINLVIMDINLPGK 60 M IL+ +D+ R L GYDV ++ A + + ++ D +LV+ D+ +P + Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 NGLLLARELRE-QANVALMFLTGRDNEVDKILGLEIGADDYITKPFNPRELTIRARNLLS 119 N L +++ + ++ ++ ++ ++ + I E GA DY+ KPF+ EL L+ Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 RT 121 Sbjct: 121 EP 122