>PF07675#Cleaved Adhesin Length = 1358 Score = 34.3 bits (78), Expect = 0.002 Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 9/56 (16%) Query: 681 DQGATVSYNVYRSTSSSDVFTPEHRIATGVTALTYKDPGLAPRYYYYVVTAVAAEG 736 + +Y +YR+ + +IA+GVT TY+DP LA +Y Y V V G Sbjct: 1254 GNAPSYTYTIYRNNT---------QIASGVTETTYRDPDLATGFYTYGVKVVYPNG 1300
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 30.2 bits (67), Expect = 0.018 Identities = 18/44 (40%), Positives = 22/44 (50%) Query: 185 GGFAGAELYDKVNAYAAAARPELAPRLTELYRGLRPATDAETYV 228 G A A V+ Y AR EL+ RLT L L PAT+ Y+ Sbjct: 175 AGEARATAPSTVSPYGPEARAELSSRLTTLRNTLAPATNDPRYL 218
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 45.7 bits (108), Expect = 2e-07 Identities = 16/60 (26%), Positives = 18/60 (30%) Query: 15 PQRQPPPPAIPPHQPLPDGTAPLPPAPPTVPPPPPLPPAPPTVPPPPPPHPPAAPPAGPA 74 P PP A+ P P P P P P+ P P P P P P Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPK 111 Score = 34.2 bits (78), Expect = 0.001 Identities = 18/76 (23%), Positives = 20/76 (26%), Gaps = 4/76 (5%) Query: 5 QPGSSADEPEPQRQP-PPPAIPPHQPLPDGTAPLPPAPPTVPPPPPLPPAPPTVPPPPPP 63 EPEP+ P PP P P P P P P P P Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASP 124 Query: 64 ---HPPAAPPAGPAGK 76 PA + A Sbjct: 125 FENTAPARLTSSTATA 140
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 113 bits (283), Expect = 2e-32 Identities = 74/262 (28%), Positives = 119/262 (45%), Gaps = 28/262 (10%) Query: 10 AVVTGASRGIGLATVQALTAEGVRVVAAARTITPELKETGAL--------AIPVDLLTPD 61 A +TGA++GIG A + L ++G + A K +L A P D+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSA 70 Query: 62 APAQLIDRATTELGDLDLLVNNVGGGDGGEGQTGGFLSFTDQQWQQSLDLNFLAAVRTSR 121 A ++ R E+G +D+LVN G + G S +D++W+ + +N SR Sbjct: 71 AIDEITARIEREMGPIDILVNV-----AGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 122 AALPSLLRRR-GALVNISSNGARMPHAGPVTYTTAKAALTAFGKALAEEFGPQGVRINTI 180 + ++ RR G++V + SN A +P Y ++KAA F K L E +R N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 181 SPGPVRTAM----WESPDGYGAELARSMGVTQEQLLAQIPAAMGMTTGRLLEPSEVATAV 236 SPG T M W +G + S+ E IP +L +PS++A AV Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSL----ETFKTGIP------LKKLAKPSDIADAV 235 Query: 237 AYLASPLAASMSGTDLLIDGGS 258 +L S A ++ +L +DGG+ Sbjct: 236 LFLVSGQAGHITMHNLCVDGGA 257
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 54.6 bits (131), Expect = 2e-11 Identities = 36/199 (18%), Positives = 68/199 (34%), Gaps = 16/199 (8%) Query: 6 RALRADTERTVRTILEAAERVLAADP--AATMEQIAAAAGVARTTVHRRFATREALVEAL 63 R + + + T + IL+ A R+ + + ++ +IA AAGV R ++ F + L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 64 ATWATERFHQAV-EAARPLTSPPLVALHQVTANVLQVKI------GWSFAMSRTAPSDPE 116 + + E PL L ++ +VL+ + + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 117 AARVHA-------DVLAQCDQLFRRAQEAGLVSADTDLEWARRVYYALIHEASEEGREVV 169 A V + + +Q + EA ++ AD A + I E Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 170 DIGAVDQLAARVVDTLLHG 188 + + A V LL Sbjct: 183 QSFDLKKEARDYVAILLEM 201
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.7 bits (82), Expect = 4e-05 Identities = 20/92 (21%), Positives = 33/92 (35%), Gaps = 7/92 (7%) Query: 60 EQLRACDESFLGVRDELRLVGAVAWTRLPNGALDICRLVVHPVAHRRGVATALLDALDSI 119 + ++ E +G + NG I + V ++GV TALL +I Sbjct: 58 SYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHK--AI 115 Query: 120 E-----PAELTIVSTGTANLPAVALYRRRGFI 146 E ++ T N+ A Y + FI Sbjct: 116 EWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>BACYPHPHTASE#Salmonella/Yersinia modular tyrosine phosphatase signature. Length = 468 Score = 27.8 bits (61), Expect = 0.019 Identities = 9/34 (26%), Positives = 18/34 (52%) Query: 91 CGGGVGRTGTALSAICVFEGMDPKEAVKWVRQNY 124 C GVGRT + A+C+ + + + +V+ + Sbjct: 403 CRAGVGRTAQLIGAMCMNDSRNSQLSVEDMVSQM 436
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 30.0 bits (67), Expect = 0.015 Identities = 16/54 (29%), Positives = 28/54 (51%), Gaps = 2/54 (3%) Query: 255 IVGNALGFDAMPSTAEREEAFAAFDLRPLLDQDANGPMLVVNGTEDVHVPLDDT 308 I GN + FD++P +E + L+ + DA G ++ + T + VP+ DT Sbjct: 490 ITGNTVVFDSLPRLGSKETVEFSVTLKAVSAGDARGEAILSSDT--LTVPVSDT 541
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 1e-15 Identities = 29/205 (14%), Positives = 65/205 (31%), Gaps = 19/205 (9%) Query: 11 RRPGGRAARVRQAVLAATMEVLAEEGIARLSIAEVAARAGVNETTVYRRWGSREKLVLDA 70 R+ A RQ +L + + +++G++ S+ E+A AGV +Y + + L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 71 M------LAGSDEGIPVPDTGTVRTDLAAFARALTEYLATPTGRAVARAASLSSDD---- 120 + + G + L + E T R + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 121 -PDLAEAWQTFWQSRLDQAGAIVSRAVERGELPTDTDAALALELLCSPLQTRSLLGHRPI 179 + +A + D+ + +E LP D A ++ + L+ + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS--GLMENWLF 180 Query: 180 EPDLPERLT------DLVLDGLRGR 198 P + ++L+ Sbjct: 181 APQSFDLKKEARDYVAILLEMYLLC 205
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 111 bits (278), Expect = 1e-28 Identities = 87/405 (21%), Positives = 169/405 (41%), Gaps = 29/405 (7%) Query: 27 FVVIMDTSIIGVALPKMQADLGFSQENLSWVFNAYVVAFGGLLLLGGRLSDLLGAKRLFS 86 F +++ ++ V+LP + D + +WV A+++ F + G+LSD LG KRL Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 87 AGWVVLAVGSLTAGLA-SQVWVELAGRALQGVGAALIAPSALTLLMTLFGARPQELGKAF 145 G ++ GS+ + S + + R +QG GAA AL +++ + GKAF Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFP--ALVMVVVARYIPKENRGKAF 141 Query: 146 ALYGAAAPAGGTAGVFLGGVITQYASWPWVFYINIPVAVIVLAATP-AVMPSGAGRRGSI 204 L G+ G G +GG+I Y W + + IP+ I+ ++ +G Sbjct: 142 GLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHF 199 Query: 205 DLAGAVTVTAGLAAAVYAIVRAPETGWGSAETWLVLLGGVALIAAFVAIQSKRREPLMRL 264 D+ G + ++ G+ + + L+ V FV K +P + Sbjct: 200 DIKGIILMSVGIVFFMLFTTSY---------SISFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 265 GIWR-APNLAGANIAQLLMA--AAWIPMWFFLNLYLQQVLGLDAFASGSA-LLPMTVAIM 320 G+ + P + G ++ A ++ M + ++ V L GS + P T++++ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSM---VPYMMKDVHQLSTAEIGSVIIFPGTMSVI 307 Query: 321 IMMIVLAPRLISRFGPKPLIVLGLLALGAGMFWLSLARPDGNFWVDVLPASLLSAVGMSL 380 I + L+ R GP ++ +G+ L S + W + ++ V L Sbjct: 308 IFGYI-GGILVDRRGPLYVLNIGVTFLSVSFLTASFL-LETTSWFMTI---IIVFVLGGL 362 Query: 381 AFIPSLGT--ALSSARPEEGGLASGIVNTSYQVGSALGLAAMTAL 423 +F ++ + SS + +E G ++N + + G+A + L Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.033 Identities = 11/66 (16%), Positives = 23/66 (34%), Gaps = 8/66 (12%) Query: 28 RPFVAVTIREVASAAGVSVSTVSRAFTAPDQV--------QPTTRQRILDAATKLGYSPN 79 + + ++ E+A AAGV+ + F + + + L+ K P Sbjct: 27 QGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPL 86 Query: 80 PAARSL 85 R + Sbjct: 87 SVLREI 92
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 43.8 bits (103), Expect = 4e-07 Identities = 23/101 (22%), Positives = 31/101 (30%) Query: 74 LPDPPVEPTRSHTPEPAGPPPEEPAPAPEPPPRPAQPAAVQPEPPAQPAPVRPEPPAPDA 133 LP P + + PP+ P PEP P PEPP + V +P Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 102 Query: 134 PVAAVQPAKPVARRPVVRPVTADEEPDGPACPACGTPNLPG 174 P +R V + P PA T + Sbjct: 103 PKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTAT 143 Score = 41.9 bits (98), Expect = 2e-06 Identities = 22/117 (18%), Positives = 36/117 (30%), Gaps = 2/117 (1%) Query: 36 PVAPEPLGPSEQAGPAAVPAVAAAPETEGPASGAPPSPLPDPPVEPTRSHTPEPAGPPPE 95 P++ + P++ P AV P P P + PV + P P Sbjct: 49 PISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPV 108 Query: 96 EPAPAPEPPPRPAQPAAVQPEPPAQPAPVRPEPPAPDAPVAAVQPAKPVARRPVVRP 152 + P+ +P + P PA RP A + + R + R Sbjct: 109 KKVEQPKRDVKPVESRPASPFENTAPA--RPTSSTATAATSKPVTSVASGPRALSRN 163
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 40.8 bits (95), Expect = 9e-07 Identities = 23/182 (12%), Positives = 52/182 (28%), Gaps = 17/182 (9%) Query: 10 TTERLVRAGAELADEIGFAQTTPAELARRFGVKTASLYSHVKNAHDLKTKIALLALEELA 69 T + ++ L + G + T+ E+A+ GV ++Y H K+ DL ++I L+ + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 70 DQVSTAVAGRAGKDALTAFANVYR--DYALEHPGRFAAAQFRLDPQTAAASAGVRHAQMT 127 + A G + + + R + V Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 128 RAILRGYNLAEPHQTHAVRLLGSVFSGYVGLETAGGFSHSTPDSQESWTEILNALDALLR 187 L Y+ + + ++ + + + L+ Sbjct: 132 NLCLESYDR---------------IEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME 176 Query: 188 TW 189 W Sbjct: 177 NW 178
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 33.1 bits (75), Expect = 0.001 Identities = 32/203 (15%), Positives = 62/203 (30%), Gaps = 34/203 (16%) Query: 46 HPDRTP-ASVTATSFAGTVALS--------NCSGSLVRMPNSQATDPGLVMTNGHCLETG 96 + DR T +A + SG +V ++TN H ++ Sbjct: 73 NNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVV--------GKDTLLTNKHVVD-- 122 Query: 97 FPSAGQVITNQSSTRSFTLLNASAGTAGTLRANKVVYATMTDTDVTLYQLTKTYAQIQQS 156 + + ++F + + + D+ + + + Sbjct: 123 -----ATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIG 177 Query: 157 TGIAPLTLSAAHPVQGHAIDVVSGYWKRVYSCFVDGFAYRLKE--GQWTWKDAVRYTPEC 214 + P T+S Q + V+GY D + E G+ T+ + Sbjct: 178 EVVKPATMSNNAETQVNQNITVTGY-------PGDKPVATMWESKGKITYLKGEAMQYDL 230 Query: 215 QVIGGTSGSPVIDTTTGQVTAIN 237 GG SGSPV + +V I+ Sbjct: 231 STTGGNSGSPVFN-EKNEVIGIH 252
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 36.3 bits (83), Expect = 6e-04 Identities = 41/159 (25%), Positives = 68/159 (42%), Gaps = 24/159 (15%) Query: 637 RHPNISRT--IAIVEAA--PEWALIMELLDGPALSQVLE------ENGQLPPASVVQMGR 686 +HPN++ +A+V E AL+M+ +DG S L + G++ + + Sbjct: 189 KHPNLANVHGMAVVPYGNRKEEALLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWGTIK 248 Query: 687 CLGEALL----HLHSLNLCRIDLKPSNIIAHPIRG-PVVVDLGIARWTGVDENDRDTAVG 741 + LL HL + D+KP N++ G PVV+DLG+ +G Sbjct: 249 FIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGF----- 303 Query: 742 SMVGTPAYMAPEQLRSATEADIRSDLYALGVVLYQCITG 780 T ++ APE A +SD++ + L CI G Sbjct: 304 ----TESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.7 bits (98), Expect = 4e-06 Identities = 62/308 (20%), Positives = 106/308 (34%), Gaps = 30/308 (9%) Query: 45 VLP-LFAVLTLNAD-AGRLGVLRAVGQAPILLLSLFVGAWVDRWRARTVMVLTDVGRTLA 102 VLP L L + D G+L A+ + +GA DR+ R V++++ G + Sbjct: 27 VLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVD 86 Query: 103 LGATAVAGLLGWLGLPALL---VVAFAVGALSVFFDVAYQTSLVRLMKRDQLVRGNSALE 159 A A L L + ++ A A + D+ R + Sbjct: 87 YAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGF---------MS 137 Query: 160 GSRSAAQIGGPALGGALVSL-LSAP--IAAASSALFFALSFLSIRRIRRIESIPECSERP 216 + GP LGG + AP AAA + L F + + E P E Sbjct: 138 ACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREAL 197 Query: 217 PGVWRRIHEGLCFVVSDTSLRTVCLASAAFQFSFAAMMTVYLLFLPRELHLSGTAVGLAL 276 + + T + + Q ++++F H T +G++L Sbjct: 198 NPL-----ASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISL 252 Query: 277 AATGP-GALLGSMLAASLPSRFGH-GAVLVSAAALGDGVFLCVPALHGSSAVTVPALLLV 334 AA G +L +M+ + +R G A+++ A G G L A G + Sbjct: 253 AAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRG------WMAFPI 306 Query: 335 SFVFGTGG 342 + +GG Sbjct: 307 MVLLASGG 314
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.4 bits (123), Expect = 5e-10 Identities = 23/112 (20%), Positives = 44/112 (39%), Gaps = 3/112 (2%) Query: 2 IADDDEVTRSGLRTLLAAQPGISVVGEAADGVEAVEQARRLRADVVLMDVRMPRRNGIEA 61 +ADDD R+ L L+ + G V ++ D+V+ DV MP N + Sbjct: 8 VADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 62 TRQLLAESAEPPKVVVITTFENDGYVTAALSAGASGFVLKRLPVRQIAEAVR 113 ++ + P V+V++ A GA ++ K + ++ + Sbjct: 66 LPRIKKARPDLP-VLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 28.2 bits (63), Expect = 0.005 Identities = 10/52 (19%), Positives = 20/52 (38%) Query: 31 SEITQQEYEEAKAALDAEQAEHVAAIDAEAQERARQDYEALIAAGIPPETAA 82 +E + YEE +AA + ++ E + + + E G P + Sbjct: 233 TEEEVKAYEEKRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDG 284
>cloacin#Cloacin signature. Length = 551 Score = 34.3 bits (78), Expect = 3e-04 Identities = 33/116 (28%), Positives = 40/116 (34%), Gaps = 19/116 (16%) Query: 107 GAGGGGNNAGSAGEASSFGGTVTAIGGNGGG-DGMTTGTTNTTSSGTSAPLAGKGQITMG 165 G G G+N G+ + + G T +G GG DG + N G S G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGS-----------G 51 Query: 166 GGPGEGAIRMGMRGLSGRGGDSHLGFGGYGRSTSGPGGASRGRGGGGGGAFSSDGA 221 G G G SG G G G G T G A G A S+ GA Sbjct: 52 SGIHWG-------GGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGA 100
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.043 Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 1/78 (1%) Query: 94 QGLGVREIARRLGRDPSTISRELRRNAATRGGQLDYRAS-IAQWKAEPAARRPKTPKLVA 152 + EIA+ G I + + + S I + + E A+ P P V Sbjct: 30 SSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVL 89 Query: 153 DERLREYVQDRLAGDVRR 170 E L ++ + + RR Sbjct: 90 REILIHVLESTVTEERRR 107
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.1 bits (192), Expect = 6e-20 Identities = 36/178 (20%), Positives = 62/178 (34%), Gaps = 14/178 (7%) Query: 15 PDKRAERSRRTREKIVAAARELFVAQGYGATSLQEVADRAGVAVQTVYFVFRNKRALFKD 74 K + ++ TR+ I+ A LF QG +TSL E+A AGV +Y+ F++K LF + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 75 VVDTS-------IAGDVEPVTTMDRDWFRAACAEPTAAGQLRAHVRGVRDILSRVAPIMP 127 + + S R + R + +I+ + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 128 LIAAAAATDPEIAAQWPAGPDPRYSVQHAAAKALTSKPDARPDVDTARAADLLYGLLS 185 +A + + Y K D+ T RAA ++ G +S Sbjct: 122 EMAVVQQAQRNLCLES-------YDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYIS 172
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.012 Identities = 19/60 (31%), Positives = 24/60 (40%) Query: 238 QGGPAVSGQTVSAPTPAPVPAVPVSAPAPVPPVSPAAASQEPAVPDPLAKPDHVGPDPVG 297 +G +V+G + AP AP P P P P P V VP+ P P P G Sbjct: 97 EGLESVAGIVMGAPAGAPAPKPPRPEPPPRPVVEKECWETIQPVPEHAVPPSFWHPAPKG 156
>INTIMIN#Intimin signature. Length = 939 Score = 35.0 bits (80), Expect = 8e-04 Identities = 47/311 (15%), Positives = 94/311 (30%), Gaps = 21/311 (6%) Query: 89 GANPNSIAVTPDNAHVYVSNRGSNTVSVIDTTTNSVSTTITGFTGGLQGIAIAPDGLHAY 148 G+N + + + SN T++V+ +T FT + DG A Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITVLSNGQVVDQVGVTDFTA--DKTSAKADGTEA- 577 Query: 149 VITFSGLVYVIDTTTNTIVGSPITLAGGADPRFLAITPDSKFVY---VTELGLGQVQVID 205 IT++ V + S ++G A + + + GQV V Sbjct: 578 -ITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSA 636 Query: 206 TTSN---SITTTITGFTQPTGIAITPDGLDAYVADFGTNTVSVIDTTTNTIVGSPINVGL 262 T+ ++ F T +IT D A ++ T P++ Sbjct: 637 KTAEMTSALNANAVIFVDQTKASITEIKADKTTAV-ANGQDAITYTVKVMKGDKPVSNQE 695 Query: 263 APYGLAITPDGTQVYATNVNDGTVTAIDTSTNTPTATITIGAGSSNYKLAVTPDSTRVYV 322 + + +G TST + ++ + P+ Sbjct: 696 VTFTTTLGKLS-NSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVK-APEVEFFTT 753 Query: 323 TDFTTSSVTVIDTTTNTVSTTITGITNPFGDAIAAN--------ASASLSIGKSHSGHFT 374 ++ ++ T T+ + A+ +++ + SG T Sbjct: 754 LTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQVT 813 Query: 375 QGQRGTYTITV 385 ++GT TI+V Sbjct: 814 LKEKGTTTISV 824
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 64.7 bits (157), Expect = 2e-12 Identities = 28/101 (27%), Positives = 44/101 (43%), Gaps = 5/101 (4%) Query: 721 PVAKATASATDGPVPLKVDFSSKGSNDPDGDALSYAWDFDGDGTYDSTEADPSHTYTAKG 780 P A + ++ V +++F S D DG+ +Y WDF GDG S EA +H Y G Sbjct: 775 PKAVIKSDSS-VIVEEEINFDGTESKDEDGEIKAYEWDF-GDGE-KSNEAKATHKYNKTG 831 Query: 781 DVVAQLKVTDSTG--KSGYANIPITAGNTTPKVTIDFPVSG 819 + +L VTD+ G + I + + P + Sbjct: 832 EYEVKLTVTDNNGGINTESKKIKVVEDKPVEVINESEPNND 872 Score = 42.0 bits (98), Expect = 1e-05 Identities = 46/308 (14%), Positives = 82/308 (26%), Gaps = 102/308 (33%) Query: 638 AYFEGASFFYEWSRNYVKEVRFDQDQKLLKINDFLSS---------------QKFNKPMD 682 AYF + + + NYV +V F + ++ ++ N Sbjct: 739 AYF--VNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKAVIKSDSSVIVEEEINFDGT 796 Query: 683 MTFGPDGSLYVLEWGSSFGGGN-----------NDSGLYRIDYA----QGKRIPVAKATA 727 + DG + EW FG G N +G Y + G +K Sbjct: 797 ESKDEDGEIKAYEW--DFGDGEKSNEAKATHKYNKTGEYEVKLTVTDNNGGINTESKKIK 854 Query: 728 SATDGPVPL-----------------KVDFSSKGSNDPDGDALSYAWDF----------- 759 D PV + K + KG+ + + Y +D Sbjct: 855 VVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYSDKYYFDVAKKGNVKITLN 914 Query: 760 -------------DGDGTYDSTEADPSHTYTAKGDVVAQ-----LKVTDSTGKSGYANIP 801 +GD A + KG+ + L V +SG + Sbjct: 915 NLNSVGITWTLYKEGDLNNYVLYATGNDGTVLKGEKTLEPGRYYLSVYTYDNQSGTYTVN 974 Query: 802 ITAG----------------------NTTPKVTIDFPVSGKLISFGDKIPYKVTVTDPED 839 + + KV + + G L + K Y + + +P D Sbjct: 975 VKGNLKNEVKETAKDAIKEVENNNDFDKAMKVDSNSKIVGTLSNDDLKDIYSIDIQNPSD 1034 Query: 840 GPVDCSKV 847 + + Sbjct: 1035 LNIVVENL 1042
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 32.1 bits (72), Expect = 0.001 Identities = 28/106 (26%), Positives = 42/106 (39%), Gaps = 6/106 (5%) Query: 11 MTAAADSVDREANHLTELDSAIGDADHGSNLHRGFAAVRAALDKELPQTPGAVLMLAGRQ 70 +TAA S++ A + +A R AA+RAA +P V AGR Sbjct: 207 LTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRG 266 Query: 71 LIATVGGASGPLYGTLLRRTGKALGDAPRVARQQLAEALGVGVAAV 116 LI GA+ +L + A+ RV + VG A++ Sbjct: 267 LIQVAQGAA-----SLAQAISDAIAVLGRVLASA-PSVMAVGFASL 306
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 37.8 bits (87), Expect = 8e-05 Identities = 59/247 (23%), Positives = 100/247 (40%), Gaps = 20/247 (8%) Query: 97 ISAKKGVPDVAQIEYYALSQYALTKSVADLKPYGAEKLADSYSPGPWNSVQAGDGIYGLP 156 ++A PD+ + YA + +A++ P A D P W++V+ + P Sbjct: 76 VAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKA--FQDKLYPFTWDAVRYNGKLIAYP 133 Query: 157 MDSGPMALFYNKRVFDKYEIAVPTTWDEYVEAARKLHKADPKAYITSDLGDAGLTTSLLW 216 + ++L YNK + P TW+E + A K KA K+ + +L + T L+ Sbjct: 134 IAVEALSLIYNKDLLPN----PPKTWEE-IPALDKELKAKGKSALMFNLQEPYFTWPLIA 188 Query: 217 QAGSHPYKV-----DGAEVGIDFTDAGATKYTETWQKLIDEKLVSPIAGWSDDWYKGLGD 271 G + +K D +VG+D +AGA LI K ++ +S Sbjct: 189 ADGGYAFKYENGKYDIKDVGVD--NAGAKAGLTFLVDLIKNKHMNADTDYSIA-EAAFNK 245 Query: 272 GTIATLPSGAWMPANFASGVKGASGDWRAAPLPQWTKGATGSSENGGSSLALPELGKNRE 331 G A +G W +N + + ++ LP + KG G S + N+E Sbjct: 246 GETAMTINGPWAWSN----IDTSKVNYGVTVLPTF-KGQPSKPFVGVLSAGINAASPNKE 300 Query: 332 LAYAFVE 338 LA F+E Sbjct: 301 LAKEFLE 307
>cloacin#Cloacin signature. Length = 551 Score = 34.3 bits (78), Expect = 7e-04 Identities = 25/78 (32%), Positives = 33/78 (42%), Gaps = 16/78 (20%) Query: 261 PAGSSYGHGDPYAGNHSHGQGHGHYEERHHDGGHRSGPGMGTAVAA------------GA 308 P G G G + G HG G G+ + GG G +AVAA GA Sbjct: 45 PWGGGSGSGIHWGGGSGHGNGGGN----GNSGGGSGTGGNLSAVAAPVAFGFPALSTPGA 100 Query: 309 AGLAVGVVGGMVAAEVVD 326 GLAV + G ++A + D Sbjct: 101 GGLAVSISAGALSAAIAD 118
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 36.5 bits (84), Expect = 3e-06 Identities = 15/48 (31%), Positives = 28/48 (58%), Gaps = 2/48 (4%) Query: 1 MFGI--SEIAIILIVVILVLGAKRLPDLARSAGKSARILKAEAKAMKE 46 MF I SE+ ++ I+ ++VLG +RLP ++ R L++ A ++ Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQN 48
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 24.7 bits (53), Expect = 0.040 Identities = 10/34 (29%), Positives = 20/34 (58%) Query: 7 VQNRLSPTPDATPQAHDARLAHYLADAVDDDRDA 40 + + L + D+ P +++ARL +L+D D+ A Sbjct: 385 ITDILGVSADSRPDSNEARLHEFLSDGTIDEESA 418
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 219 bits (560), Expect = 7e-66 Identities = 106/326 (32%), Positives = 152/326 (46%), Gaps = 38/326 (11%) Query: 191 SASKVSRLWYDGKVQASLDKSVPQIGAPEAWAKGVDGKGVKVAVLDTGVDLNNADIKGRL 250 +V + + + V I AP W + G+GVKVAVLDTG D ++ D+K R+ Sbjct: 8 IPYQVIKQEQQ---VNEIPRGVEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPDLKARI 63 Query: 251 TATRSFVDGAA----TVQDGHGHGTHVASTIVGSGANSGGKYKGVAPGADLLVGKVLTDG 306 R+F D +D +GHGTHVA TI + +G GVAP ADLL+ KVL Sbjct: 64 IGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATENENGVV--GVAPEADLLIIKVLNKQ 121 Query: 307 GGGLSSWIIDGMEWAAAQGADVVNMSLGGSASSPQDAKTEVVDRLSTTTGTLFVISAGND 366 G G WII G+ +A Q D+++MSLGG E V + + L + +AGN+ Sbjct: 122 GSGQYDWIIQGIYYAIEQKVDIISMSLGGPEDV--PELHEAVKKA-VASQILVMCAAGNE 178 Query: 367 GPGA---TTVLSPGTADSALTVGAVDKSDVLARFSSRGPRVGDSAIKPEITAPGVGIVAA 423 G G + PG + ++VGA++ + FS+ V ++ APG I++ Sbjct: 179 GDGDDRTDELGYPGCYNEVISVGAINFDRHASEFSNSNNEV-------DLVAPGEDILS- 230 Query: 424 RAAGTSMGTPVDANYTAADGTSMAAPHVAGAAALLAQR-----HPDWTGRRIKAALVTHA 478 T Y GTSMA PHVAGA AL+ Q D T + A L+ Sbjct: 231 --------TVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRT 282 Query: 479 KPSNAYSVYQQGNGRVDVPAALDPAL 504 P S +GNG + + A + + Sbjct: 283 IPLG-NSPKMEGNGLLYLTAVEELSR 307
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 261 bits (668), Expect = 2e-80 Identities = 165/504 (32%), Positives = 225/504 (44%), Gaps = 61/504 (12%) Query: 74 LGLGGQEQLLVKSVLKDADGTVHARYERTFAGLPVLGGDLVVHTAANGSAKGV--TKATN 131 LG +E+L + D G R+E+ A +G LV H +G + T N Sbjct: 68 LGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVN-DGELSSLSGTLIPN 126 Query: 132 ATITVASTTAARSAGSAKTFAVGRAKAKGVAKARAGT-----ARKVVWAASGTPTLAWET 186 T AA S A+ A A V K R R V++ TP LA+E Sbjct: 127 LDKRTLKTEAAISIQQAEMIAKQD-VADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEV 185 Query: 187 VVGGTQADGTPSELHVITDAKSGKKLFEYQGIE---------------TGIGNSKYSGQV 231 V P + DA GK L ++ ++ G+G Q Sbjct: 186 NV--RFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQK 243 Query: 232 TIGTTPAN--GGYSMTDGTRGGH-KTYDLNHGNSGTGTLFTDPDDTWGDGTTNDPQTTAV 288 I TT ++ G Y + D TRG TYD + G+L+ D D+ + AV Sbjct: 244 YINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQF----FASYDAAAV 299 Query: 289 DAAYGAQLTWDYYKDVHGRNGIKNDGVAAYTRVHYGNNYVNAFWDDNCFCMTYGDGAG-N 347 DA Y A + +DYYK+VHGR A + VHYG Y NAFW+ + M YGDG G Sbjct: 300 DAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQ--MVYGDGDGQT 357 Query: 348 AKPLT-SIDIAAHEMTHGVTSNTAGLIYRGESGGLNEATSDIMAAAVEFWANNASDPGDY 406 P + ID+ HE+TH VT TAGL+Y+ ESG +NEA SDI VEF+AN D+ Sbjct: 358 FLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNP---DW 414 Query: 407 LNGDQI---DIHGDGTPLRYMDKPSKDGKSADAWYPGIESID---VHYSSGPANHWFYLA 460 G+ I + GD LR M P+K G + D VH +SG N YL Sbjct: 415 EIGEDIYTPGVAGDA--LRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSGIINKAAYLL 472 Query: 461 SEGSGAKTVGGVDYDSPTSDGLPVSAIGRDAAAKIWYKALTIYMTSSTDYAGARTATLQA 520 S+G G+ V+ IGRD KI+Y+AL Y+T +++++ R A +QA Sbjct: 473 SQGG-------------VHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQA 519 Query: 521 AADLYGLGSDTYINAANAWAAINV 544 AADLYG S + A+ A+ V Sbjct: 520 AADLYGSTSQEVNSVKQAFNAVGV 543
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 54.3 bits (130), Expect = 2e-10 Identities = 38/231 (16%), Positives = 74/231 (32%), Gaps = 19/231 (8%) Query: 77 RKAVAAAADRGMSSLADALSDRTARLGE---KQDEGDEEEYEPEEGGAEYEEEEEPEEEE 133 + +A + + A A T KQ+ E+ E + + E +E + Sbjct: 1014 NEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAK 1073 Query: 134 PEAEYEEGQAE----EEEEEEEQPEEEYEEEEEQEERQPK----------RRRSSLQPAR 179 + E E +E Q E E ++E + K + S + P + Sbjct: 1074 SNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQ 1133 Query: 180 SRGGAARKKAAPARGEKPRTAKKTAARKTAPPKKT--AAKKTAPAKKTAARKTAPPKKTA 237 + + +A PAR P K +T T AK+T+ + ++ Sbjct: 1134 EQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGN 1193 Query: 238 AKKTAPAKKTAARKTAPPKKTAAKKTAPAKKSAARKTTSSKRAASKRADRR 288 + P T A ++ K + + R + A+ ++ R Sbjct: 1194 SVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR 1244 Score = 52.4 bits (125), Expect = 1e-09 Identities = 31/194 (15%), Positives = 72/194 (37%), Gaps = 7/194 (3%) Query: 96 SDRTARLGEKQDEGDEEEYEPEEGGAEYEEEEEPEEEEPEAEYEEGQAEEEEEEEEQPEE 155 ++ TA+ E E + + E +E + E E+EE+ + + E+ Sbjct: 1059 TETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEK 1118 Query: 156 EYEEEEEQEERQPKRRRSSLQPARSRGGAARKKAAPARGEKPRTAKKTAARKTAPPKKTA 215 E + + PK+ +S + + + AR+ ++P++ T A P K+T+ Sbjct: 1119 TQEVPKVTSQVSPKQEQS--ETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS 1176 Query: 216 AKKTAPAKKTAARKTAP-----PKKTAAKKTAPAKKTAARKTAPPKKTAAKKTAPAKKSA 270 + P ++ T P+ T T P + + + + ++ P Sbjct: 1177 SNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEP 1236 Query: 271 ARKTTSSKRAASKR 284 A +++ + + Sbjct: 1237 ATTSSNDRSTVALC 1250 Score = 43.5 bits (102), Expect = 8e-07 Identities = 34/231 (14%), Positives = 77/231 (33%), Gaps = 10/231 (4%) Query: 62 AELQEQLKGEVFDAGRKAVAAAADRGMSSLADALS----DRTARLGEKQDEGDEEEYEPE 117 AE +Q V + A A + + +T + + E E + Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTET 1100 Query: 118 EGGAEYEEEEEPEEEEPEAEYEEGQAEEEEEEEEQPEEEYEEEEEQEERQPKRRRSSLQP 177 + A E+EE+ + E + + + ++EQ E + E E P +++ Sbjct: 1101 KETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPT---VNIKE 1157 Query: 178 ARSRGGAARKKAAPARGEKPRTAKKTAARKTAPPKKTAAKKTAPAKKTAARKTAPPKKTA 237 +S+ PA+ + + + ++ + P T A T P + Sbjct: 1158 PQSQTNTTADTEQPAK--ETSSNVEQPVTESTTVNTGNSVVENPENTTPA-TTQPTVNSE 1214 Query: 238 AKKTAPAKKTAARKTAPPKKTAAKKTAPAKKSAARKTTSSKRAASKRADRR 288 + + + ++ P A ++ + + A +S + +D R Sbjct: 1215 SSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDAR 1265
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.0 bits (65), Expect = 0.005 Identities = 13/44 (29%), Positives = 26/44 (59%) Query: 46 RVSAPRAMRYAAEQLQELLGRAPESVSAVKPTEGGWQADVEVLE 89 R +P+++ +++LGR P +++A++P + G AD V E Sbjct: 45 RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTE 88
>SECA#SecA protein signature. Length = 901 Score = 25.2 bits (55), Expect = 0.035 Identities = 5/17 (29%), Positives = 9/17 (52%) Query: 41 EAERGACLEYIDQHWTD 57 E+G L+ +D W + Sbjct: 761 HFEKGVMLQTLDSLWKE 777
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 1e-14 Identities = 26/88 (29%), Positives = 42/88 (47%), Gaps = 1/88 (1%) Query: 1 MVRLTRAQQQERTRAAVLAAAKAEFTERGYAAAKVDEIAERAELTRGAVYSNFPSKRALY 60 M R T+ Q+ + TR +L A F+++G ++ + EIA+ A +TRGA+Y +F K L+ Sbjct: 1 MARKTK-QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 LAVLVDMVERAAAAEHSDSAKRSGTTEQ 88 + E AK G Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLS 87
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 83.3 bits (206), Expect = 6e-19 Identities = 56/247 (22%), Positives = 94/247 (38%), Gaps = 37/247 (14%) Query: 257 VPFGEALFGRQGEDVVSGSSLTEPLSELADREPEVWTRLLSALTRLEENYRD-ACYVEFT 315 V +A + + +S+T+ +E+ +L +AL + +E R E + Sbjct: 14 VAIAKAFIHLEPNVDIEKTSITDVSTEIE--------KLTAALEKSKEELRAIKDQTEAS 65 Query: 316 FEAGELWILQVRRGRFVGRAAVRVAVDLADAGTIGRDEALLRVSPQH---LTHVRTPRIT 372 A + I V + + + AL VS + + Sbjct: 66 MGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNEYMK 125 Query: 373 --AIEPRDLFTRGLGASPGVAVGRVATTADSAARLAAGGPVVLLRPETSPLDMHGL--AA 428 A + RD+ R LG GV G +AT A+ V++ + +P D L Sbjct: 126 ERAADIRDVSKRVLGHLIGVETGSLATIAE---------ETVIIAEDLTPSDTAQLNKQF 176 Query: 429 AAGVVTARGGPTSHAAVVARSMGKPAVVGAANLTVDAADGCVRAGGRTLPEGTLIALDGT 488 G T GG TSH+A+++RS+ PAVVG +T + G ++ +DG Sbjct: 177 VKGFATDIGGRTSHSAIMSRSLEIPAVVGTKEVTEK------------IQHGDMVIVDGI 224 Query: 489 GGEVVVG 495 G V+V Sbjct: 225 EGIVIVN 231
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 28.5 bits (63), Expect = 0.021 Identities = 14/44 (31%), Positives = 25/44 (56%) Query: 59 EERHGRHRYVRVADRRVVELIESLAALAPQGSARPRSLSASGRQ 102 + GR V+V D R VE+ +++ A GS P ++A+G++ Sbjct: 86 DSCFGRMYTVKVNDDRNVEITQAVPEYATVGSPYPIEITATGKR 129
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.8 bits (64), Expect = 0.007 Identities = 11/49 (22%), Positives = 17/49 (34%), Gaps = 2/49 (4%) Query: 81 PQLRGSGLGREILRQAEDEAHARGCRTAVLYTITFQAPG--FYHKQGWK 127 R G+G +L +A + A +L T FY K + Sbjct: 99 KDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>PF05844#YopD protein Length = 295 Score = 27.3 bits (60), Expect = 0.027 Identities = 17/52 (32%), Positives = 21/52 (40%), Gaps = 2/52 (3%) Query: 52 LPALPAALPALPAAPSQPNPSYGYQQPAQQGYAPMQPAQLQHAPAPYIPQQP 103 L A AA+P+ P AP S G Q A + P PA P+Q Sbjct: 8 LAATQAAIPSEPIAPGAAGRSVGTPQAAAEL--PQVPAARADRVELNAPRQV 57
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 37.0 bits (85), Expect = 3e-04 Identities = 31/138 (22%), Positives = 39/138 (28%), Gaps = 12/138 (8%) Query: 419 SPAEAGFYVSAEGRGTFHGCRVTGSEGYGFHVMDGCRTTLTRCRTERCARGGYEFAEGGT 478 S A A V T G +TG G M G L R R GG Sbjct: 214 SGAPAAVSVLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGA 273 Query: 479 AHGDG-------TGAGPVVE-----DCTSDESALRSPAAPAPTVLTATQSASGLLGAVPG 526 G G GPV++ D + L AP + A + G V G Sbjct: 274 VPGGAVPGGFGPGGFGPVLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGARVTVSG 333 Query: 527 PRAAEPTPATVPAAEPVR 544 + P + R Sbjct: 334 GSLSAPHGNVIETGGARR 351
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 44.8 bits (106), Expect = 5e-07 Identities = 23/123 (18%), Positives = 44/123 (35%), Gaps = 16/123 (13%) Query: 13 LRCLVTGASGYIGGRLVPALLDAGHRVRAL--------ARTPRKLRDHPWADRVEVVEGD 64 ++ LVTGA+G+IG + LL+AGH+V + + + + + D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 65 VSDAASVRAAMRD--MDVAYYLVHALGSGPGFEETDREAAR-VFGAQ-----ARAAGVGR 116 ++D + + + H L E A + G R + Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 117 IVY 119 ++Y Sbjct: 121 LLY 123
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 65.8 bits (160), Expect = 1e-15 Identities = 28/169 (16%), Positives = 57/169 (33%), Gaps = 13/169 (7%) Query: 4 RAMSTPDRLIEATQELLWERGYVGTSPKAIQQQAGAGQGSMYHHFAGKPDLALTAIRRTA 63 A T +++ L ++G TS I + AG +G++Y HF K DL + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 64 SQMRETARQLF-DGPGTAYERISTYLLR---------ERDVLRGCPVGRLTMDPEVIASD 113 S + E + PG + L+ R +L + E+ Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 114 ELRAPVDETIGWLRGRLAEIIQEGLDQGEFTRLLVPEDVAATIVATVQG 162 + + + R+ + ++ ++ L+ A + + G Sbjct: 128 QAQRNLCLE---SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.3 bits (89), Expect = 5e-05 Identities = 62/283 (21%), Positives = 94/283 (33%), Gaps = 12/283 (4%) Query: 54 HQTGASASTLGLALLGVSAGAVVTMMLTGRLCRRFGSHPVTVVCGVLLPLGIALPAQTHS 113 + + G+ L + + G L RFG PV +V + A+ A Sbjct: 36 VHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPF 95 Query: 114 ALALGLVLLVFGAAYGGMNVAMNSAAVDLVAALRRPVMPSF-HAAFSLGGMVGAGLGGLV 172 L + +V G VA A D+ R F A F G + G LGGL Sbjct: 96 LWVLYIGRIVAGITGATGAVAGAYIA-DITDGDERARHFGFMSACFGFGMVAGPVLGGL- 153 Query: 173 AGGLSPATHLFVLTGIGLLVTAATGPVLLRQPAPKPASTADDAEKPRQPAGRARRMV--- 229 GG SP F + L TG LL + + R R + Sbjct: 154 MGGFSPHAPFFAAAALNGL-NFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 230 -LLFGVIALCTAYGEGALADWGALHLEQDLHAHPGIAAAGYSLFAL--AMTAGRLSGTAL 286 L V + G+ A W + E H + F + ++ ++G + Sbjct: 213 AALMAVFFIMQLVGQVPAALW-VIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGP-V 270 Query: 287 LERLGQTRTLVAGGATAAAGMLLGSLAPTTWLALLGFAVTGLG 329 RLG+ R L+ G G +L + A W+A + G Sbjct: 271 AARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG 313 Score = 32.1 bits (73), Expect = 0.004 Identities = 42/161 (26%), Positives = 55/161 (34%), Gaps = 33/161 (20%) Query: 252 LHLEQDLHAHPGIAAAGYSL--FALAMTAGRLSGTALLERLGQTRTLVAGGATAAAGMLL 309 L D+ AH GI A Y+L FA A G LS +R G+ L+ A AA + Sbjct: 35 LVHSNDVTAHYGILLALYALMQFACAPVLGALS-----DRFGRRPVLLVSLAGAAVDYAI 89 Query: 310 GSLAPTTWLALLGFAVTGLGLANIFPVAVGRAGELAGPGGVAAAST--------LGY--- 358 + AP W+ +G V G+ A G A T G+ Sbjct: 90 MATAPFLWVLYIGRIVAGI-----------TGATGAVAGAYIADITDGDERARHFGFMSA 138 Query: 359 ---GGMLLGPPAIGFLADWFSLPLALTTVALLAAAAAALGY 396 GM+ GP G + FS A L G Sbjct: 139 CFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGC 178
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.8 bits (124), Expect = 6e-10 Identities = 24/118 (20%), Positives = 45/118 (38%), Gaps = 6/118 (5%) Query: 2 IRVLLADDQLLVRAGF-RALLDAQPDIEVAGEAADGEEAVRLVRELRPDTVLMDIRMPHL 60 +L+ADD +R +AL A D+ + + R + D V+ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITS---NAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGLAATRAITGDFELSGVKVVMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVR 118 + I + V++++ +A GA +L K + EL+ + Sbjct: 61 NAFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.049 Identities = 57/362 (15%), Positives = 106/362 (29%), Gaps = 80/362 (22%) Query: 85 FGSSAAAMIYLAAGYPYGPVFLAVAVGCFSAVVSG-----------HRR----------- 122 G + YG L + + + G R+ Sbjct: 18 IGWGVYTLTGFGFASLYGSPKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQII 77 Query: 123 -AAWTAV---GMVWLGHVLVAHWLYRWLPPSDDH-PAAWGQELG---VAAWVVAIIAAAE 174 A GMVW VA+ L + P A+ L + VV + Sbjct: 78 LRVLPACVVIGMVWF----VANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSL 133 Query: 175 FVRVRREQWADQRAEREAAEQRR-ADEERLRMARE------LHDVLAHSISVINVQSSVG 227 ++AE + + A E +L + + + L ++I Sbjct: 134 LYFGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNAL-NNIR--------- 183 Query: 228 LALLDSDPEQARTALTTIKAASKEALGEVRQVLDTLRTPGDAPRTPAPGLDRLPELVEQA 287 AL+ DP +AR LT++ + +L +L +D +L Sbjct: 184 -ALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTV-------VDSYLQLASIQ 235 Query: 288 AGAGLTVTVETD-GVRGAVPPGADLAAFRIVQEALTNVVRHSGSRTAQ-----VRIGYGP 341 L + + + P +VQ + N ++H ++ Q ++ Sbjct: 236 FEDRLQFENQINPAIMDVQVP------PMLVQTLVENGIKHGIAQLPQGGKILLKGTKDN 289 Query: 342 ARIRLRIDDEGPATGDDAG-GSGNGLAGMRERAAALRG-----TIEAGPRADGGFRVRAE 395 + L +++ G + +G GL +RER L G + G Sbjct: 290 GTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSE---KQGKVNAMVL 346 Query: 396 LP 397 +P Sbjct: 347 IP 348
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 46.5 bits (110), Expect = 2e-08 Identities = 19/112 (16%), Positives = 42/112 (37%), Gaps = 4/112 (3%) Query: 5 RGARERARIEVTAAIKGEARKQLAAEGAAKLSLRAVARELGMASSALYRYFPSRDELLTA 64 R ++ A+ E I A + + +G + SL +A+ G+ A+Y +F + +L + Sbjct: 3 RKTKQEAQ-ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 65 LIVDAYDSVGESAEAAHRAARADAAPHITRWTVVAHAVRDWALAHPHEYALI 116 + + ++GE D + V + + L+ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLS---VLREILIHVLESTVTEERRRLLM 110
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 57.0 bits (137), Expect = 8e-12 Identities = 48/170 (28%), Positives = 74/170 (43%), Gaps = 3/170 (1%) Query: 12 ALEGAVVAVAGAAGPAGRATLLRLAEAGATVVASDADATRLAEAVDAARYAHGGATVTGD 71 +EG + + GAA G A LA GA + A D + +L + V + + Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAE--ARHAEAF 62 Query: 72 TVDLLDLAAAREWADKTEKEFGRIDGLVHLVGGWRGSATFAETDLADWNLLEKLLIRTVQ 131 D+ D AA E + E+E G ID LV++ G R + +D +W + V Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD-EEWEATFSVNSTGVF 121 Query: 132 HTSLAFQEGLQRSDRGRYVLISAAGASQPTAGNAAYAASKAAAEAWTLAL 181 + S + + + G V + + A P AAYA+SKAAA +T L Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.6 bits (69), Expect = 0.004 Identities = 8/33 (24%), Positives = 21/33 (63%) Query: 3 VSLALLLLGALAAVVTPRLMARADWPEREPVVA 35 + + ++++G LA++V P LM + +++ V+ Sbjct: 15 IMVVIVIIGVLASLVVPNLMGNKEKADKQKAVS 47
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 31.7 bits (72), Expect = 0.002 Identities = 20/152 (13%), Positives = 42/152 (27%), Gaps = 20/152 (13%) Query: 41 DNRTKAQAGG---GPSVVAPGKPGEPARTLSAEEAAKAAGDDAPNSADFRYVQ----MMI 93 ++ Q G G SV + AEE + S D R + + Sbjct: 23 SSQIVNQTLGQFRGESVQIVSGTLQSIAD-MAEEVTFVFSERKELSLDKRKLSDSQARVS 81 Query: 94 QHHAQALELTGLVPARSESTAIKRLAERITAGQKPEIGAMEGWLKHNGGEK--------- 144 Q + VP + + L ++ + ++ +L+ E Sbjct: 82 DVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEGKSEEPSEQFKMLCG 141 Query: 145 -RKSGHDHSAMPGMATPAQ--LDQLRTADGAA 173 R + + ++ + L + G Sbjct: 142 LRDALKGRPELAHLSHLVEQALVSMAEEQGET 173
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.6 bits (144), Expect = 2e-13 Identities = 42/203 (20%), Positives = 71/203 (34%), Gaps = 23/203 (11%) Query: 1 MPRNRQQIPKAEREAVLVDSAWELFAVKGYKGTSLTEVGKAAGVAANAVRWYFPTKDDLF 60 M R +Q + R+ +L D A LF+ +G TSL E+ KAAGV A+ W+F K DLF Sbjct: 1 MARKTKQEAQETRQHIL-DVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 AATLGRLFLRERERVEADPV-IGGDPRRQLVTFLADL--ESYRGLHREAYDRMDESPALA 117 + E GDP L L + + R + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 118 ------------DVYSRMREWLEGRLLAAVAS-RLSEGADVEPVADMAHVLFEGLLVSA- 163 ++ + +E L + + L A + GL+ + Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 164 -----RELDRPTEEFIDLLMEAL 181 +L + +++ +L+E Sbjct: 180 FAPQSFDLKKEARDYVAILLEMY 202
>SSBTLNINHBTR#Streptomyces subtilisin inhibitor signature. Length = 144 Score = 63.7 bits (154), Expect = 5e-16 Identities = 37/86 (43%), Positives = 45/86 (52%), Gaps = 1/86 (1%) Query: 47 IRGVALFCPPAPDAHHPHAAAACAAIDWAEGDLDALPGSPR-LCIEGYDPVTATATGNRD 105 +R V L C P HP AAAACA + A GD AL +C Y PV T G Sbjct: 59 LRAVTLTCAPTASGTHPAAAAACAELRAAHGDPSALAAEDSVMCTREYAPVVVTVDGVWQ 118 Query: 106 GRPVSWQRTFPNACVMDAVTGPVFRF 131 GR +S++RTF N CV +A + VF F Sbjct: 119 GRRLSYERTFANECVKNAGSASVFTF 144
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 51.7 bits (123), Expect = 3e-09 Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 21/196 (10%) Query: 20 LRIGGGVAALAALPPAL-TACSDSSSGSGKLRIVGVADQQKPIEELVALYRKSHPDDEFS 78 ++ G + AL+AL + +A + + GKL I D K L + +K D Sbjct: 3 IKTGARILALSALTTMMFSASALAKIEEGKLVIWINGD--KGYNGLAEVGKKFEKDTGIK 60 Query: 79 TSFAPTDQVQTVVRTQLAGGNAPDV----HVLYPGSGSAMSMVELARAGLLADLS-DQAW 133 + D+++ A G+ PD+ H + G A++GLLA+++ D+A+ Sbjct: 61 VTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGG---------YAQSGLLAEITPDKAF 111 Query: 134 TKEVPANFHPAYRYKGKTYLYSAGSSAIGAIYNKKAFAEAGVEPPKTWSELLDFCAKLKA 193 ++ A RY GK Y A+ IYNK PPKTW E+ +LKA Sbjct: 112 QDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPN----PPKTWEEIPALDKELKA 167 Query: 194 KGVIPIALGAQTPWVT 209 KG + Q P+ T Sbjct: 168 KGKSALMFNLQEPYFT 183
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.4 bits (63), Expect = 0.006 Identities = 21/103 (20%), Positives = 36/103 (34%), Gaps = 8/103 (7%) Query: 33 DHDGVARLISRDPGALLLAERDGLLAGTVIAGFDGW--RCSVYRLAVHPDCRRRGIATAL 90 D D + + A L + G I W + +AV D R++G+ TAL Sbjct: 52 DDDMDVSYVEEEGKAAFLYYLENNCIGR-IKIRSNWNGYALIEDIAVAKDYRKKGVGTAL 110 Query: 91 MAAAEQ--RFVSLGGRRV---DAMVLEANERAHHTWTAGGYHR 128 + A + + G + D + + A H + G Sbjct: 111 LHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDT 153
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 32.4 bits (74), Expect = 0.003 Identities = 37/170 (21%), Positives = 63/170 (37%), Gaps = 14/170 (8%) Query: 7 LLVAVLLSLACGAFVAAEF--SLTTVERGQLERAVEQGERGAASAMKAVRSLTFQLSGAQ 64 LL + +L ++ A L TV +LE ++G+ G A + R LT L+ Q Sbjct: 69 LLQITIFALGIMPYITASIILQLLTVVIPRLEALKKEGQAGTAKITQYTRYLTVALAILQ 128 Query: 65 -LGITVTNLVVGMLSEPSIAKLIRGPVEAVGLSPSVASSLALVLGTALSTVFLMVVGELV 123 G+ T + S+ + S+ +++ +V+ T +M +GEL+ Sbjct: 129 GTGLVATARSAPLFGRCSVG-------GQIVPDQSIFTTITMVICMTAGTCVVMWLGELI 181 Query: 124 PKNWAI---SSPLAVAKAVATPQRAFTAVFRPFISHLNNTANRIVRRIGL 170 I S L AT A A+ + V +GL Sbjct: 182 TD-RGIGNGMSILMFISIAATFPSALWAIKKQGTLAGGWIEFGTVIAVGL 230
>PF06580#Sensor histidine kinase Length = 349 Score = 32.5 bits (74), Expect = 0.003 Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 9/72 (12%) Query: 306 ILQESLTNVLRH------SGAVPVRVRISVTNGRLEMEVTN--PLTDSMGTPGGGSGLRG 357 ++Q + N ++H G + ++ + NG + +EV N L G+GL+ Sbjct: 259 LVQTLVENGIKHGIAQLPQGGK-ILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQN 317 Query: 358 IRERAALLGGKA 369 +RER +L G Sbjct: 318 VRERLQMLYGTE 329
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 29.3 bits (66), Expect = 0.031 Identities = 24/84 (28%), Positives = 35/84 (41%), Gaps = 14/84 (16%) Query: 4 ILIRGAKVLG----GEPQDVLVDGETIAAVGTGIEAGDATVVEAEGQILLPGLVDLHTHL 59 I ++ ++ G P + G TI VG G E V+ EG+I+ G +D H H Sbjct: 88 IGLKDGRIAAIGKAGNPD--MQPGVTII-VGPGTE-----VIAGEGKIVTAGGMDSHIHF 139 Query: 60 REPGREDSETVLTGTKAAAVGGFT 83 P + E L +GG T Sbjct: 140 ICP--QQIEEALMSGLTCMLGGGT 161
>PERTACTIN#Pertactin signature. Length = 922 Score = 28.1 bits (62), Expect = 0.045 Identities = 22/81 (27%), Positives = 24/81 (29%) Query: 10 PPPQGPGSGPVGWTHQAQHPGPPGPPPTTPPTPRGWSGPAPQHAPAPVSRETTGHIQLPP 69 G S A P P P P P+ P P P P R+ PP Sbjct: 554 ANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Query: 70 GGPVPLPAPPAEPGTGSATLA 90 G A A TG LA Sbjct: 614 AGRELSAAANAAVNTGGVGLA 634
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 26.0 bits (57), Expect = 0.044 Identities = 9/43 (20%), Positives = 18/43 (41%) Query: 1 MFRRTFWFTAGAAAGVWATAKVNRKLKQLTPESLAAQAADKAI 43 ++ W T + G W + + + L + L Q++D I Sbjct: 169 LYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYI 211
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 329 bits (844), Expect = e-105 Identities = 140/693 (20%), Positives = 270/693 (38%), Gaps = 96/693 (13%) Query: 24 VRNVVLVGHSGSGKTTLVEALALTAGAVNRAGRVEDGATVSDYDEIEHRQQRSVQLSLVP 83 + N+ ++ H +GKTTL E+L +GA+ G V+ G T +D +E ++ ++Q + Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 84 VEWGGYKINLLDTPGYTDFVGELRAGLRAADAALFVVSAAQEADAVAGSTRAVWDECAAV 143 +W K+N++DTPG+ DF+ E+ L D A+ ++SA D V TR ++ + Sbjct: 63 FQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK---DGVQAQTRILFHALRKM 119 Query: 144 GMPRAIVVTHLDTARTSFDEMTRICGEIFGGDDPDAVLPLYLPVHGPEGPDGHAPLTGLT 203 G+P + +D + +I + V+ Sbjct: 120 GIPTIFFINKIDQNGIDLS---TVYQDIKEKLSAEIVI---------------------- 154 Query: 204 GLLTQRIFDYSSGDRQENPPADAQRTTLQEARNRLIEGIIAESEDETLMDRYLGGGEIDI 263 Q++ Y P T E + +IEG ++ L+++Y+ G ++ Sbjct: 155 ---KQKVELY--------PNMCVTNFTESEQWDTVIEG------NDDLLEKYMSGKSLEA 197 Query: 264 ETLIDDLERAVARGAFHPVLSAAPAAEGARQGIGTVELLDLITGGFPTPLERPLPEVTPL 323 L + + PV + A+ IG L+++IT F + R Sbjct: 198 LELEQEESIRFHNCSLFPVYHGS-----AKNNIGIDNLIEVITNKFYSSTHRG------- 245 Query: 324 HGAARPVLTCDPHGPLVAEVVKTASDPYVGRVSLVRVFSGTLRPDETVHVFGHGLNDPCH 383 L +V K R++ +R++SG L ++V + Sbjct: 246 ------------QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRIS--------- 284 Query: 384 ETRPFHEAEVRVGALSSPFGKHQRPLTACIAGDLAC----VAKLGSAETGDTLSAQGQPL 439 + ++++ + + + +G++ KL S GDT + Sbjct: 285 -----EKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV-LGDTKLLPQRER 338 Query: 440 LMDPWTTPDPLLPLAIEAHSKADEDKLSQGLSRLVAEDPTMRLEQNQDTHQVVLWCLGEA 499 + +P PLL +E + L L + DP +R + TH+++L LG+ Sbjct: 339 IENP----LPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKV 394 Query: 500 HQDVALDRLRSRYGVQVDAVPHKVSLRETFAGPSTGRGRHVKQSGGHGQYAICEIDVEPL 559 +V L+ +Y V+++ V E + + +A + V PL Sbjct: 395 QMEVTCALLQEKYHVEIEIKEPTVIYMERPLK--KAEYTIHIEVPPNPFWASIGLSVSPL 452 Query: 560 PPGSGIEFVDKVVGGAVPRQFIPSVEKGVRAQAARGVAAGHPLVDIRITLRDGKSHSVDS 619 P GSG+++ V G + + F +V +G+R +G+ G + D +I + G +S S Sbjct: 453 PLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLY-GWNVTDCKICFKYGLYYSPVS 511 Query: 620 SDAAFQTAGALALREAAADTRIQLLEPVAEIQVLVPDDYVGPVMSDLSGRRGRVIGTEQS 679 + A F+ + L + +LLEP ++ P +Y+ +D ++ T+ Sbjct: 512 TPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLK 571 Query: 680 GAGRTLVRAEVPELEIGRYAIDLRSLSHGAGRF 712 ++ E+P I Y DL ++G Sbjct: 572 N-NEVILSGEIPARCIQEYRSDLTFFTNGRSVC 603
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 34.0 bits (78), Expect = 0.002 Identities = 14/102 (13%), Positives = 30/102 (29%), Gaps = 7/102 (6%) Query: 108 SATRLRKARD-------ARLTAVTALFGFLFLPGMLLWVIAFRLRDSLGNTKDKALAALG 160 + ++R AR + + + + L + +++ Sbjct: 10 TPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQSYLPFS 69 Query: 161 NALLPVIGIVALLFLIKLPLTGFLALYVRAMIVAPVIGWLIA 202 AL V+ V L F +A + G+LI+ Sbjct: 70 QALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLIS 111
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 29.7 bits (66), Expect = 0.025 Identities = 24/78 (30%), Positives = 38/78 (48%), Gaps = 9/78 (11%) Query: 132 EAGVVHRDLKPSNILL--SPKGPRIIDFGIAWATGASTLTHVGTAVGSPGFLAPE-QVRG 188 +AGVVH D+KP N++ + P +ID G+ +G + F APE V Sbjct: 263 KAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGF------TESFKAPELGVGN 316 Query: 189 ATVTPATDVFSLGATLAY 206 + +DVF + +TL + Sbjct: 317 LGASEKSDVFLVVSTLLH 334
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 74.7 bits (183), Expect = 2e-18 Identities = 34/168 (20%), Positives = 64/168 (38%), Gaps = 12/168 (7%) Query: 40 MAK--QQRAIRTRRLILDSAATMIERNGYTATSIDGISTTAGTTKGAVYFHFPSKGDIAA 97 MA+ +Q A TR+ ILD A + + G ++TS+ I+ AG T+GA+Y+HF K D+ + Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 98 ALFDEAHDSLRAIAT-----RARGPEASPLQSLIDTTHLLVRQFNGDPVTRACIQLCLER 152 +++ + ++ + P + + LI V + I E Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTV-TEERRRLLMEIIFHKCEF 119 Query: 153 HSPAPQ----ARAYRLTWASTVRLLLESAAARREFREGVSAHAVAALV 196 R L + L+ + + A ++ Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIM 167
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 83.9 bits (207), Expect = 4e-22 Identities = 42/205 (20%), Positives = 76/205 (37%), Gaps = 15/205 (7%) Query: 11 QERALRTRRAILEAASIVFEKRGFVAAPLSEIIAASGVTKGALYFHFSSKEELARGVIEA 70 ++ A TR+ IL+ A +F ++G + L EI A+GVT+GA+Y+HF K +L + E Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 71 QFSAMGQL------RLQGSPLQQAIDSTHAVAHALQHVPLVRAGVRLVIEQGSFTEPDPE 124 S +G+L + G PL + V + R + +I + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEER-RRLLMEIIFHKCEFVGEMA 124 Query: 125 PYLRWVEPAQ--------AFLEQARTEGELRPEVDVLAVAQLIVALFTGTQLMAQVLTQW 176 + L+ L ++ A ++ +G Q Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQS 184 Query: 177 EDLDERITAFWRVVLPGLAMPEALR 201 DL + + ++L + LR Sbjct: 185 FDLKKEARDYVAILLEMYLLCPTLR 209
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 28.4 bits (63), Expect = 0.035 Identities = 17/35 (48%), Positives = 23/35 (65%), Gaps = 1/35 (2%) Query: 129 SAAALEEALGLWRGP-ALEGVGGGVLCGSAAARLD 162 SA LE+ +GL GP A GV GG++ G+ + RLD Sbjct: 21 SAIELEDEVGLECGPYAKVGVVGGMITGAESTRLD 55
>PF07520#Virulence protein SrfB Length = 1041 Score = 32.6 bits (74), Expect = 0.002 Identities = 21/97 (21%), Positives = 35/97 (36%), Gaps = 8/97 (8%) Query: 41 AGKTTLLNIASSYLFPSTGTAKILGEQLGGVGTDVFELRPRIG--IAGIAMAEKLPRRQT 98 AG + + S+ + P + Q GG +R G I G RRQ Sbjct: 635 AGDDLVHRVISAIVLPRLQDSI---AQAGGQFVAER-MRELFGGDIGGQEQQTVQRRRQF 690 Query: 99 VLQTVLTAAYGMTATWHENYEAVDEERARAFLDRLGM 135 ++ ++ A + + E+ E D D LG+ Sbjct: 691 SIRVLVPLAEAILSAC-EDAEEADRIDIP-VADVLGL 725
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.8 bits (176), Expect = 7e-17 Identities = 27/115 (23%), Positives = 46/115 (40%), Gaps = 2/115 (1%) Query: 6 IRVLLVDDHQVVRRGLRTFLEIQDDIEVVGEASDGAEGVARTEELRPDVVLMDIKMPGTD 65 +L+ DD +R L L V S+ A D+V+ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GIEALRKLRELENPAKVLIVTSFTEQRTVVPALRAGASGYVYKDVDPDALAGAIR 120 + L ++++ VL++++ T + A GA Y+ K D L G I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 2e-04 Identities = 22/121 (18%), Positives = 39/121 (32%), Gaps = 4/121 (3%) Query: 37 VPANAEGKPEAQTPVSAAPVVLASVAGTPQV----KAVQASIIEQHSTAEQLVKAADLAR 92 VP+N E P T V K ++ + A + Sbjct: 1010 VPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVA 1069 Query: 93 AEKAAAVKAKAEAAAKAKAAAAAEVKARAEAKARAAAQVKAKAAAERTETQAASRSEART 152 E + VKA + A++ + + E K A + + KA E +TQ + ++ Sbjct: 1070 KEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQV 1129 Query: 153 P 153 Sbjct: 1130 S 1130
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.8 bits (74), Expect = 0.007 Identities = 46/162 (28%), Positives = 63/162 (38%), Gaps = 16/162 (9%) Query: 34 DLTIDDARVSWRHATISWGGHSWFIEDHGSTNGTYVQGRRIHQLEIGPGSAVHLGNATDG 93 DL + D V R A+ G H ++ + GS + G + ++ GSA A Sbjct: 487 DLGLSDKLVVMRDAS---GQHRLWVRNSGSEPAS---GNTMLLVQTPRGSAATFTLANKD 540 Query: 94 PRLSIG------AAAGADVYSGQGAGAQQAPVQQPQQGGAGRQAPVPPQQQQPQQGWQQA 147 ++ IG AA G +S GA A AP PQ G P P Q PQ Sbjct: 541 GKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPAPQPG----PQPGPQPPQPPQPPQPPQ 596 Query: 148 PQVQPQQQPAQPQQPQVPHQQGMARTPGAGGPGGVAGAPPVY 189 P PQ+QP P ++ A A GGV A ++ Sbjct: 597 PPQPPQRQPEAPAPQPPAGRELSAAANAAVNTGGVGLASTLW 638
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.8 bits (67), Expect = 0.022 Identities = 23/122 (18%), Positives = 44/122 (36%), Gaps = 4/122 (3%) Query: 72 EVQDGLHMSAGAAGVLTSVPPLCFAI-FGVMAPRLARRFGPGAVVCAGMIAITAG-LVIR 129 ++D +S G + P I FG + L R GP V+ G+ ++ L Sbjct: 282 MMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTAS 341 Query: 130 PLVGGTAGFLAASALALMG--IAVSNVLMPVIVKRWFPDRVGSMTGLYSMALALGTSLAA 187 L+ T+ F+ + ++G V+ ++ G+ L + L Sbjct: 342 FLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGI 401 Query: 188 AV 189 A+ Sbjct: 402 AI 403
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 48.5 bits (115), Expect = 7e-09 Identities = 56/267 (20%), Positives = 99/267 (37%), Gaps = 38/267 (14%) Query: 5 LDGKRILITGVLMESSIAFHTAKVAQEQGAEVILTAF----PRPTLTERIAKKLPKPAKV 60 ++GK ITG I A+ QGA + A + K + A+ Sbjct: 6 IEGKIAFITGA--AQGIGEAVARTLASQGAHI--AAVDYNPEKLEKVVSSLKAEARHAEA 61 Query: 61 IELDVTNAEHLDRLAGLVRDELGSLDGVVHSIGF---APQDALGGNFLNTPFESVSTAMH 117 DV ++ +D + + E+G +D +V+ G +L E Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSL-------SDEEWEATFS 114 Query: 118 VSAFSLKSLAMACKPLM--SEGGSIVGLTFDAQYAWPQYDW--MGPAKAALEATSRYLAR 173 V++ + + + + M GSIV + + P+ +KAA ++ L Sbjct: 115 VNSTGVFNASRSVSKYMMDRRSGSIVTVGSNPAGV-PRTSMAAYASSKAAAVMFTKCLGL 173 Query: 174 DLGKDDIRCNLISAGPIGS-----------MAAKSIPGFSELADVWNSRSPLAWNMSDPE 222 +L + +IRCN++S G + A + I G E + + PL ++ P Sbjct: 174 ELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLE---TFKTGIPLK-KLAKPS 229 Query: 223 PAGRGVVALLSDFFPKTTGEIIHVDGG 249 V+ L+S T + VDGG Sbjct: 230 DIADAVLFLVSGQAGHITMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 138 bits (348), Expect = 4e-42 Identities = 78/252 (30%), Positives = 125/252 (49%), Gaps = 16/252 (6%) Query: 3 RSVLVTGGNRGIGLAIARAFAENGDKVAITYRSGEPPQILTEAGVLAVR------CDITD 56 + +TG +GIG A+AR A G +A + E + + + R D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 57 AEQVEQAYKEIEDKHGPVEVLVANAGITKDQLLMRMSEEDFTSVLDTNLTGTFRVVKRAN 116 + +++ IE + GP+++LV AG+ + L+ +S+E++ + N TG F + + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 RGMLRAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPG 176 + M+ + G +V + S + A YA+SKA V F + L EL NI N+V+PG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 177 FVDTDMTQVL-----TEEQR-KGIVSQ----VPLGRYAQPEEIAAAVRFLASDDASYITG 226 +TDM L EQ KG + +PL + A+P +IA AV FL S A +IT Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 227 AVIPVDGGLGMG 238 + VDGG +G Sbjct: 249 HNLCVDGGATLG 260
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 200 bits (509), Expect = 5e-62 Identities = 107/347 (30%), Positives = 140/347 (40%), Gaps = 62/347 (17%) Query: 152 MEPLQWDLPAIKADQAHQKTLGSSKVTVAVIDTGVDDTHPDLAPNFNRGASASCVSGAPD 211 + + + I+A +T G V VAV+DTG D HPDL G + + D Sbjct: 19 VNEIPRGVEMIQAPAVWNQTRGR-GVKVAVLDTGCDADHPDLKARIIGGRNFT------D 71 Query: 212 TTDGAWRPKTGESDHGTHVAGTIAAAKNGVGVTGVAPGVKVAGIKVANPDGFFYTESIVC 271 +G + HGTHVAGTIAA +N GV GVAP + IKV N G + I+ Sbjct: 72 DDEGDPEIFKDYNGHGTHVAGTIAATENENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQ 131 Query: 272 GFVWAAEHGVDVTNNSYYTDPWMFNCKNDLDQGALVEAVARATRYAEHKGTVNVASAGNS 331 G +A E VD+ + S D L EAV +A + + +AGN Sbjct: 132 GIYYAIEQKVDIISMSL---------GGPEDVPELHEAVKKAVA----SQILVMCAAGN- 177 Query: 332 KFDLASGAIDDTTSPNDTTAATRTIDPRECLDIPAMLPGVVTVSATGAKGLKSSYSNYGN 391 G DD T L P V++V A S +SN N Sbjct: 178 -----EGDGDDRTD---------------ELGYPGCYNEVISVGAINFDRHASEFSNSNN 217 Query: 392 GVIDVAAPGGDSTVYQTPAPPATSGLILSTLPGGKYGYKAGTSMASPHVAGVAALIKS-- 449 V D+ APG D ILST+PGGKY +GTSMA+PHVAG ALIK Sbjct: 218 EV-DLVAPGED---------------ILSTVPGGKYATFSGTSMATPHVAGALALIKQLA 261 Query: 450 ---THPHASAAAVKALLTAEADATACGAPYDFNGDGKIDAVCEGGKN 493 + + A L + NG + AV E + Sbjct: 262 NASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEELSRI 308
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 64.3 bits (156), Expect = 3e-14 Identities = 49/169 (28%), Positives = 80/169 (47%), Gaps = 4/169 (2%) Query: 5 EGQVAVVTGAASGIGLAMARRFAAEGLKVVLADVEEGALDKAAGELRRDGAQVLARAVDV 64 EG++A +TGAA GIG A+AR A++G + D L+K L+ + A DV Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 65 GERESVQALAEAAYDTFGAVHVLCNNAGVGSGAEGRMWEHEPNDWKWAFAVNVWGVFHGI 124 + ++ + G + +L N AGV G + +W+ F+VN GVF+ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLR--PGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 125 QAFVPRMIAGGGPGHVVNTSSGDGGIAPLPTASVYAVTKSAVVTMTESL 173 ++ M+ G +V S G+ P + + YA +K+A V T+ L Sbjct: 125 RSVSKYMMDRRS-GSIVTVGSNPAGV-PRTSMAAYASSKAAAVMFTKCL 171
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 61.9 bits (150), Expect = 7e-14 Identities = 51/207 (24%), Positives = 83/207 (40%), Gaps = 15/207 (7%) Query: 1 MARSSLTREQVLDTAGALVKRHGPQALTMRALAAELGTAVTSIYWHVGNRESLLDALVER 60 MAR L RE V+D A L+ G LT R LA +LG ++YWHV N+ +LLDAL Sbjct: 1 MAR--LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVE 58 Query: 61 TVQEMGT--LRPAGRTPAARIVSVARGLHRELRARPHLIAMVHERGLTERMFLPAQQALV 118 + L AG + + + + A R L + E+ + + L Sbjct: 59 ILARHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQL- 117 Query: 119 HEVHAAGLRGARAAAAVRAVQFQTVGFLLVERNRERSPVQSPGEGDLWTASTADDDPALA 178 + G A+ AV T+G +L ++ + P + ++ P L Sbjct: 118 RFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPA-------APDENLPPLL 170 Query: 179 RA---LARPADPDRLFADSVRALVEGL 202 R + D ++ F + +L+ G Sbjct: 171 REALQIMDSDDGEQAFLHGLESLIRGF 197
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.1 bits (67), Expect = 0.016 Identities = 16/68 (23%), Positives = 24/68 (35%), Gaps = 4/68 (5%) Query: 9 TAAPWPTAYPQGYAVVDVETTGLARDDRIVSAAVYRLDAQGNVE----DHWYTLVNPERD 64 T + + E A D +V+ + QG V + Y + NPE Sbjct: 422 TGPLFTGTASSNLYSANFEYLTPANADPVVTTQNIIVTGQGEVVIPGGVYDYCITNPEPA 481 Query: 65 PGPVWIHG 72 G +WI G Sbjct: 482 SGKMWIAG 489
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.033 Identities = 19/115 (16%), Positives = 38/115 (33%), Gaps = 13/115 (11%) Query: 28 DFVAELGERHPELPVA--GGFIELSPPPLGDAVTELVERGVKRFAAVPLMLVSAGHAKGD 85 D + + + P+LPV A+ E+G + P L G Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFM-----TAIKAS-EKGAYDYLPKPFDLTELIGIIGR 117 Query: 86 IPAALAREKERHPGISYTYGRPLGPHPALLKVLERRVDAVLGDTDRSEVTVLLVG 140 A R + S +G A+ ++ L ++++T+++ G Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRV-----LARLMQTDLTLMITG 167
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 37.2 bits (86), Expect = 8e-07 Identities = 19/71 (26%), Positives = 39/71 (54%) Query: 1 MILAFEIALIVFSLLLMLLVLMHKGKGGGLSDMFGGGMQSSVGGSSVAERNLDRITVFIG 60 M A + ++ ++ L+ L+++ +GKG + FG G +++ GSS + + R+T + Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 LAWFACIVVLG 71 +F +VLG Sbjct: 61 TLFFIISLVLG 71
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.3 bits (112), Expect = 5e-09 Identities = 21/105 (20%), Positives = 45/105 (42%), Gaps = 2/105 (1%) Query: 2 ARAALTTDAVVDVALLITDEKGPAALTLSAVAGRAGVATPSLYKHVRNLAELRSLVSARI 61 A T ++DVAL + ++G ++ +L +A AGV ++Y H ++ ++L S + Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 62 MNEIADQVGEAVLGRSAD--EAIRAVMMAWRHYALRHPHRYSALI 104 + I + E D +R +++ + R + Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLME 111
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 51.2 bits (122), Expect = 1e-09 Identities = 32/235 (13%), Positives = 62/235 (26%), Gaps = 46/235 (19%) Query: 33 PTPVVGGTRAAQGEFPFMVRLSM-------GCGGALYAKNIVLTAAHCVDGSGNNTSITA 85 T G + + + + G + K+ +LT H VD + + Sbjct: 73 NNDRHQITDTTNGHYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALK 132 Query: 86 TAGVVDLQSSSAI-KVKSTKVLQAPGYNGKGKDWALIKLAKPID-------LPTLKIATN 137 Q + + ++ + G D A++K + + ++ N Sbjct: 133 AFPSAINQDNYPNGGFTAEQITKYSGEG----DLAIVKFSPNEQNKHIGEVVKPATMSNN 188 Query: 138 TTYNNGTFA-IAGWGAATEGGSQQRYLLKATVPFVSDADCQGAYGSDLVPGDEICAGLLD 196 + G+ + + S G + D Sbjct: 189 AETQVNQNITVTGYPGDKPVATM----------WESKGKITYLKGEAM---------QYD 229 Query: 197 TGGVDTCQGDSGGPMFRKDNAGAWIQVGIVSWGQGCARPGYPGVYSEVSTFAANI 251 T G+SG P+F + N +GI G G + V F Sbjct: 230 L---STTGGNSGSPVFNEKNE----VIGIHWGGVPNEFNGAVFINENVRNFLKQN 277
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 72.8 bits (178), Expect = 7e-17 Identities = 49/214 (22%), Positives = 87/214 (40%), Gaps = 16/214 (7%) Query: 26 DGRVVIVTGAGRGLGRAHALAFAAEGAKVVVNDLGVGPGGDGGSAGPARQVVDEIVAAGG 85 +G++ +TGA +G+G A A A++GA + D + +VV + A Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDY---------NPEKLEKVVSSLKAEAR 57 Query: 86 EAVAHGGDIATMEGAASLVAAALETFGRLDTLVNNAGFLRDRMLVNLDEDDWDAVMRVHL 145 A A D+ + A G +D LVN AG LR ++ +L +++W+A V+ Sbjct: 58 HAEAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNS 117 Query: 146 KGHFLPLKHAAAHWRAEAKAGRAPVARVVNTSSGAGLLGSVGQGNYSAAKAGIVGLTLVA 205 G F + + + +V S + Y+++KA V T Sbjct: 118 TGVFNASRSVSKYMMDRRSGS------IVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171 Query: 206 AAEMGRYGVQVNAIAPAA-RTRMTEQTFAQTMAA 238 E+ Y ++ N ++P + T M +A A Sbjct: 172 GLELAEYNIRCNIVSPGSTETDMQWSLWADENGA 205
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.009 Identities = 12/41 (29%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Query: 98 IFAVLWVVWMARAWRGRPMSIAAKPVVWWGTGAVLLIFSIV 138 + ++W V WR I KPV + A+ +IF++V Sbjct: 86 VIGMVWFVANTSIWRLLAF-INTKPVAFTLPLALSIIFNVV 125
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.6 bits (121), Expect = 5e-09 Identities = 81/345 (23%), Positives = 129/345 (37%), Gaps = 14/345 (4%) Query: 52 ATQTGLVLAVGSIPRALLMLGGGVLADRIGPRRVVIGSDAARCLVVLGLAGALLLTSPAV 111 G++LA+ ++ + G L+DR G R V++ S L + A++ T+P + Sbjct: 42 TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVS-----LAGAAVDYAIMATAPFL 96 Query: 112 WMLIAVALVFGVVDALFLPAVGALPPRITAAGQLARVQGLRGLASRTANVVGAPLGGVAV 171 W+L +V G+ A GA IT + AR G V G LGG+ Sbjct: 97 WVLYIGRIVAGITGATG-AVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMG 155 Query: 172 AFGGPRLAFAAAGVLFAVSLPLLLSLRISPSTAQETAEPSGTAWHDLTDGLRHIRRHPVL 231 F P F AA L L L + P + + P + R R V+ Sbjct: 156 GFS-PHAPFFAAAALNG--LNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 232 GPLMLVVALSELGFAGPLNLGLILLARERGWGASGMGWIVAAFGI-GAGASALLLAVRGR 290 LM V + +L P L +I W A+ +G +AAFGI + A A++ Sbjct: 213 AALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAA 272 Query: 291 VPRAGLVMCLTVLIGAVAIAALAHVPSVGLAVTVAVCIGLFAGLGGSLCGALIQTAADPA 350 + L ++ LA +A + V + G+G A++ D Sbjct: 273 RLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAMLSRQVDEE 331 Query: 351 YLGRVTSVSTLFTHA---IAPLSYPVTGAAVAAWGTGPVFVASAA 392 G++ T + PL + AA G ++A AA Sbjct: 332 RQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAA 376
>CHLAMIDIAOM6#Chlamydia cysteine-rich outer membrane protein 6 signature. Length = 547 Score = 27.7 bits (61), Expect = 0.014 Identities = 13/31 (41%), Positives = 18/31 (58%) Query: 38 SVENGQISAGGPYEQTVTSFKVAFDALKQLG 68 S E +S GP + T+T V FD+L +LG Sbjct: 474 SKELQPVSFSGPTKGTITGNTVVFDSLPRLG 504
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.6 bits (64), Expect = 0.041 Identities = 10/90 (11%), Positives = 33/90 (36%), Gaps = 1/90 (1%) Query: 55 AVAFMFTLSMLATIGFIASYVIFPVDKIVYIWPFGHVSALNFSLGLTLGVALFAIGAGAV 114 ++ + + + + + ++ I + + + +++ Sbjct: 149 LLSILIWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISIADYAFEYY 208 Query: 115 HWARTL-MSDVEVADDRHAIEATPEVKAKV 143 + + L MS E+ + +E +PE+K+K Sbjct: 209 QYIKELKMSKDEIKREYKEMEGSPEIKSKR 238
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.0 bits (70), Expect = 0.001 Identities = 17/84 (20%), Positives = 29/84 (34%), Gaps = 6/84 (7%) Query: 5 ATVLVYSDDANTREQVRLAAGRRPAADVPPVEFLECATLPAVLDALDNGGIDVCVLDGET 64 AT+LV DDA R + A R + + + + G D+ V D Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGY------DVRITSNAATLWRWIAAGDGDLVVTDVVM 57 Query: 65 APAGGMGVCRQIKDEIFHCPPVLL 88 + +IK P +++ Sbjct: 58 PDENAFDLLPRIKKARPDLPVLVM 81
>PF01206#SirA family protein Length = 76 Score = 57.8 bits (140), Expect = 5e-13 Identities = 14/68 (20%), Positives = 33/68 (48%) Query: 391 VDALGKRCPIPVIELAKVIGEVPLGGTVTVLSDDEAARLDIPAWCAMREQEYVGEEPADR 450 +DA G CP+P+++ K + + G + V++ D + D ++ E + ++ D Sbjct: 8 LDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEEDG 67 Query: 451 GSAYVVRR 458 + ++R Sbjct: 68 TYHFRLKR 75
>PF07132#Harpin protein (HrpN) Length = 356 Score = 29.3 bits (65), Expect = 0.040 Identities = 19/72 (26%), Positives = 26/72 (36%), Gaps = 2/72 (2%) Query: 225 GVGGSTPDGVLDELSGGRGGMGHGMGHDGMGGKSDSSHAGHGGSPKSAKRRSGPSRIMKK 284 G GS+ G+ L GG G G G G + G GG+ + PS +M Sbjct: 74 GGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALG--GGLGGALGAGMNAMNPSAMMGS 131 Query: 285 SFSELLDSHGGN 296 L+ G Sbjct: 132 LLFSALEDLLGG 143
>cloacin#Cloacin signature. Length = 551 Score = 32.8 bits (74), Expect = 0.004 Identities = 25/68 (36%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 448 GGTGSTGSTGPAGGSTATGGGSVGGGSVGGSGSLAATGSDV----PAGALIAASGAVVAT 503 GG+GS G G GG GG G G+L+A + V PA + A G V+ Sbjct: 48 GGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSI 107 Query: 504 GAGAVIAA 511 AGA+ AA Sbjct: 108 SAGALSAA 115
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.3 bits (65), Expect = 0.023 Identities = 9/20 (45%), Positives = 11/20 (55%) Query: 54 VLALVGPNGAGKSTLLAALA 73 + L G G GKSTL+ L Sbjct: 598 SVVLEGTGGIGKSTLINTLV 617
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.5 bits (193), Expect = 3e-20 Identities = 41/208 (19%), Positives = 68/208 (32%), Gaps = 18/208 (8%) Query: 6 PPDPSRRSERSRRAIYDAALGLVGEVGYPRTTVEAIAARAGVGKQTIYRWWPSKAAVLLE 65 + ++ +R+ I D AL L + G T++ IA AGV + IY + K+ + E Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 66 AFVALGDRVAEENGAGDARGLPDTGDLAADLKVVLRATVDELTDPAFEAPTRALAAEGIV 125 + + E L D VLR + + + R L E I Sbjct: 62 IWELSESNIGE-------LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIF 114 Query: 126 DPQLGAEFVQKLLD-------PSLRLYVARLRAAQEAGQVRADIDPRIALELLVGPLT-- 176 + + S L+ EA + AD+ R A ++ G ++ Sbjct: 115 HKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGL 174 Query: 177 -HRWLLR-TLPLTHEYADAIVDYTLHGL 202 WL + A V L Sbjct: 175 MENWLFAPQSFDLKKEARDYVAILLEMY 202
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 31.7 bits (72), Expect = 0.003 Identities = 28/186 (15%), Positives = 56/186 (30%), Gaps = 34/186 (18%) Query: 17 MDPSKPVDLPLAQTQWEDLRDRYRTLGHTVELLTPR--PELPDMVFAANGATVIDGRV-- 72 + + ++ E+L++ +L V +P+++F + I V Sbjct: 116 LTIDNMISKMISGVVTEELKNYTSSLDDLVNGANLFIIDPMPNVLFTRDPFASIGNGVTI 175 Query: 73 ------------LGARFAYQERYEEAGAHREWFRDNGFTAIHEPAHVNEGEGDFAVTASY 120 + A + ++ W ++ EG GD V Sbjct: 176 NKMFTKVRQRETIFAEYIFKYHPVYKENVPIWLNRWEEASL-------EG-GDELVLNKG 227 Query: 121 ILA-GRGFRSSPLSHNE-AQEFFG-----RPVVGLDLVDPR-YYHLDTALSVLDDAGDEI 172 +L G R+ S + A F ++ + R Y HLDT + +D Sbjct: 228 LLVIGISERTEAKSVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDY--SVF 285 Query: 173 MYYPGA 178 + Sbjct: 286 TSFTSD 291
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 64.1 bits (156), Expect = 3e-13 Identities = 84/361 (23%), Positives = 142/361 (39%), Gaps = 28/361 (7%) Query: 57 TALPPLSMDMYLPALPAVTESLHASAATVQLTLTACLTGMALGQVVVGPM----SDRWGR 112 AL + + + +P LP + L S V L AL Q P+ SDR+GR Sbjct: 14 VALDAVGIGLIMPVLPGLLRDLVHSN-DVTAHYGILLALYALMQFACAPVLGALSDRFGR 72 Query: 113 RRPLLLGMIIYVVATAICVFAPTTELLIGFRLLQGLAGAAGIVIARAVVRDMYDGVEMAR 172 R LL+ + V AI AP +L R++ G+ GA G V A + D+ DG E AR Sbjct: 73 RPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG-AYIADITDGDERAR 131 Query: 173 FFSTLMLISGVAPIVAPLIGGQVLRFTDWRGIFAVLTVVGVVLTLVVQKWLHETLPPQDR 232 F + G + P++GG + F+ F + + L L E+ + R Sbjct: 132 HFGFMSACFGFGMVAGPVLGGLMGGFSP-HAPFFAAAALNGLNFLTGCFLLPESHKGERR 190 Query: 233 HTGGIGDALRTMRGLLADRVFTGYMIAGSLAFAALFSYVSASPFVVQEIYGASPQTFS-L 291 +AL + R T +A +A + V P + I+G + Sbjct: 191 --PLRREALNPLASFRWARGMTV--VAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDAT 246 Query: 292 LFGINSVGLIVVGQINGKVLVGRISL----DKALAFGLSVIVLAAAALLLMTSGVFGHVG 347 GI+ ++ + ++ G ++ +AL G+ L T G Sbjct: 247 TIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRG------ 300 Query: 348 LVPVAAGLFVLMSAMGLAMPNTNAQALMRTKHAAGSASALLGTSSFL--IGAVASPLVGI 405 +A + VL+++ G+ MP QA++ + L G+ + L + ++ PL+ Sbjct: 301 --WMAFPIMVLLASGGIGMPAL--QAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356 Query: 406 A 406 A Sbjct: 357 A 357
>RTXTOXINC#Gram-negative bacterial RTX toxin-activating protein C signature. Length = 170 Score = 29.9 bits (67), Expect = 0.010 Identities = 11/30 (36%), Positives = 17/30 (56%), Gaps = 2/30 (6%) Query: 48 RFGIPRAYGSWADLAADDEVDVVYVATPHS 77 R P AY SWA+L+ ++E+ Y+ S Sbjct: 49 RDDYPVAYCSWANLSLENEIK--YLNDVTS 76
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.8 bits (69), Expect = 0.003 Identities = 19/51 (37%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 24 SIADMMGLNEREVRLARRTVGRGDARSLAQELLSRTQQATREAPAEPAPEI 74 S+++ M LN R V L+RR D S A+ L + Q R A E A E+ Sbjct: 965 SLSNAMILNSRLVNLSRRHTNHID--SFAKRLQALKDQ--RFASLESAAEV 1011
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 15/60 (25%), Positives = 26/60 (43%) Query: 80 DVAELTRVFVRPEHRGTGGGGLLLAAVESAARAFGISTVRLDTRNDLVEARGLYAKHGYR 139 A + + V ++R G G LL A+ + L+T++ + A YAKH + Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 161 bits (410), Expect = 2e-45 Identities = 95/406 (23%), Positives = 176/406 (43%), Gaps = 17/406 (4%) Query: 33 LLAALDQTIVSTALPTIVSDLGGLEH-LSWVVTAYLLASTAATPLWGKLGDQYGRKKLFQ 91 + L++ +++ +LP I +D +WV TA++L + T ++GKL DQ G K+L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 92 TAIVIFLIGSALCGVAQNM-PQLIGFRALQGLGGGGLIVLSMAIVGDIVAPRERGKYQGL 150 I+I GS + V + LI R +QG G L M +V + RGK GL Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 151 FGAVFGATSVLGPLLGGFFTQHLSWRWVFYINLPIGVVALLVIAAVLYIPVRRTQHTIDY 210 G++ +GP +GG ++ W + + +P+ + + L R + D Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFDI 201 Query: 211 LGTFLIASVATCLVLVASLGGTTWAWGSAQVIALAALSVLLLIAFVHVERRAAEPVIPLK 270 G L++ + L T+++ +SVL + FV R+ +P + Sbjct: 202 KGIILMSVGIVFFM----LFTTSYSIS------FLIVSVLSFLIFVKHIRKVTDPFVDPG 251 Query: 271 LFRIRTFSLVAVISFVVGFAMFGAMTYLPTFLQVVHSITPTMSG-VHMLPMVLGLLLTST 329 L + F + + ++ + G ++ +P ++ VH ++ G V + P + +++ Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 330 LSGQIVSRTGRWKVFPIAGTGITAIGLQLLHRLTETSSTLEMSIYFFVFGAGLGLVMQVL 389 + G +V R G V I G ++ L ET+S I FV G GL V+ Sbjct: 312 IGGILVDRRGPLYVLNI-GVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFTKTVI 369 Query: 390 VLVVQNAVTYEDLGVATSGATFFRSIGASFGVAVFGTIFTNRLTDK 435 +V +++ ++ G S F + G+A+ G + + L D+ Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPLLDQ 415
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 29.8 bits (66), Expect = 0.018 Identities = 20/80 (25%), Positives = 31/80 (38%) Query: 196 LPSTVASAPAEETASASASASASAVPSGPASTSPSASAPTSTSPSASTSPSPSASAASQP 255 LP+ + + T+ +A P PA A + ++PSP +AAS Sbjct: 155 LPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLTPLVAEAQSKAEVISTPSPVTAAASPL 214 Query: 256 ATASPSASTPHASRPASSAP 275 T + P + P SAP Sbjct: 215 ITPHQTQPLPTVAAPVLSAP 234
>cdtoxina#Cytolethal distending toxin A signature. Length = 258 Score = 34.7 bits (79), Expect = 9e-05 Identities = 9/60 (15%), Positives = 20/60 (33%) Query: 34 KVRNWQTGYVLGVAGGSTVGGAQIQYEVDTDNLAQKWAIDPVTSSTFLLRNLNSDMCVTA 93 + RN G + G G + + + L++L++ +C+ A Sbjct: 130 QFRNVDVGTCMTSFPGFKGGVQLSTAPCKFGPERFDFQPMATRNGNYQLKSLSTGLCIRA 189
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.0 bits (72), Expect = 0.007 Identities = 62/355 (17%), Positives = 105/355 (29%), Gaps = 42/355 (11%) Query: 119 EASHTYITAVDAHDLDRDDLEPAVAARARAELTTAKDELVRVKGELDRF---AQGLGPLL 175 E +H +T DA RD L ++ +L K +L V G D + + + Sbjct: 934 EPNHNELTLFDASKAQRDHLNVSLVGN-TVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTV 992 Query: 176 --GNAETQLARLA--PAVERARQALLGASNALDAVRASGLRADDLAARLAALAPELTKLN 231 N T A P+V + + A A ++ A + Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSE--TTETVAENSKQESKT 1050 Query: 232 QGAGRHGVPETLQRADRVLRDA------EAVRAEAAQLPERAAEIDHRL------VSLRT 279 ET + V ++A E AQ E V Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110 Query: 280 RAQALTTRTGSVEPVLSELRRRFSAACWQDLQPVPEQAAANVRQAEEKLKEAATARDEQR 339 +A+ T +T V V S++ + + Q P + +E + T D ++ Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 340 WADATSRLSTVRALLNATDEAVSAAGDRLHRLNEVAKDPQQEIQRTRFAIRDAQRLAMAG 399 A TS + T N V ++P+ T +++ Sbjct: 1171 PAKETSSNVEQPVTESTTVNT----------GNSVVENPENTTPATTQPTVNSES----- 1215 Query: 400 RNTPDPRHARPLDDAVARLERAVAGLDGRHPDYWHFLTETDAVRRTAARVVSEIR 454 N P RH R + +E A + R + D V+S+ R Sbjct: 1216 SNKPKNRHRRSVRSVPHNVEPATTSSNDRST-----VALCDLTSTNTNAVLSDAR 1265
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 34.2 bits (78), Expect = 4e-04 Identities = 21/97 (21%), Positives = 30/97 (30%) Query: 181 AEAAAEPDPAPSPVTVPSPVAAPAFPPPAFPPAPTPCPDSQATVQHQQPAYGYPQPAAAQ 240 E EP+P P P+ P A P P P P P + + +PA+ Sbjct: 70 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPF 129 Query: 241 PAPQPAPQPAYGYPQPATAPPAYSYPQPAAAAAPAPD 277 PA + + P P A + P Sbjct: 130 ENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166 Score = 30.7 bits (69), Expect = 0.005 Identities = 21/100 (21%), Positives = 29/100 (29%), Gaps = 10/100 (10%) Query: 184 AAEPDPAPSPVTVPSPVAAPAFPPPAFPPAPTPCPDSQATVQHQQPAYGYPQPAAAQPAP 243 A +P P P P P P P A P P + P+P P Sbjct: 65 AVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK----------PKPVKKVEQP 114 Query: 244 QPAPQPAYGYPQPATAPPAYSYPQPAAAAAPAPDPNFVLP 283 + +P P A + P + A A P + Sbjct: 115 KRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVA 154 Score = 30.3 bits (68), Expect = 0.006 Identities = 21/114 (18%), Positives = 32/114 (28%), Gaps = 1/114 (0%) Query: 176 ISVDEAEAAAEPDPA-PSPVTVPSPVAAPAFPPPAFPPAPTPCPDSQATVQHQQPAYGYP 234 + + P PA P VT+ +P PP P P+ + + P Sbjct: 33 LYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPV 92 Query: 235 QPAAAQPAPQPAPQPAYGYPQPATAPPAYSYPQPAAAAAPAPDPNFVLPPQGPQ 288 +P P+P P+P QP + AP Sbjct: 93 VIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAAT 146
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 29.5 bits (66), Expect = 0.027 Identities = 24/93 (25%), Positives = 36/93 (38%), Gaps = 6/93 (6%) Query: 187 DVVKERVAAITADQLATLIYTSGTTGRPKGVRLPHDNWSYM---AKATVATGLITKDDVQ 243 D + +A A QL + TG+ GV + D W ++ A+ Sbjct: 35 DSAAQTLARFEA-QLRFVQQRGLQTGQFFGVSVHPDRWQFLVLEARDGADPAPADDGWSG 93 Query: 244 YLWLPLAHVFGKVLTSGQIEVGHVTAVDGRVDK 276 Y WLPL G+V TSG I G + + + Sbjct: 94 YRWLPLRA--GRVATSGSIAGGKLNLAFAQGEA 124
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 148 bits (376), Expect = 4e-40 Identities = 107/504 (21%), Positives = 189/504 (37%), Gaps = 111/504 (22%) Query: 19 IRNFCIIAHIDHGKSTLADRMLQLTGV------VDQRQMRAQYLDRMDIERERGITIKSQ 72 I N ++AH+D GK+TL + +L +G VD+ R D +ER+RGITI++ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRT---DNTLLERQRGITIQTG 59 Query: 73 AVRLPWAPNTGEDQGRTHVLNMIDTPGHVDFTYEVSRS----------LAACEG----TV 118 W T V N+IDTPGH+DF EV RS ++A +G T Sbjct: 60 ITSFQW--------ENTKV-NIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTR 110 Query: 119 LLVDAAQGIEAQTLA-------------NLYLAMENDLT--IVP---------------- 147 +L A + + T+ +Y ++ L+ IV Sbjct: 111 ILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFT 170 Query: 148 --------------VLNK-IDLPAAQPEKFSEEL-ANLIGCQPEDVLRVSAKTGVGVDAL 191 +L K + + + + +E C V SAK +G+D L Sbjct: 171 ESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNL 230 Query: 192 LDRVVKDVPAPIGRADAPARAMIFDSVYDSYRGVVTYVRVVDGQLNKRERIRMMSTGATH 251 ++ + + R + +F Y R + Y+R+ G L+ R+ +R+ Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIK 290 Query: 252 ELLEIGVSSPEMTPADGLGVGEVGYI---ITGVKDVRQSKVGDTITSLNKGATEALGGYK 308 + E+ D GE+ + + V +GDT + E Sbjct: 291 ITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSV----LGDTKLLPQRERIE------ 340 Query: 309 DPKPMVFSGLYPLDGSDYPDLREALDKLQLNDAAL-VYEPETSAALGFGFRVGFLGLLHL 367 +P P++ + + P L +AL ++ +D L Y + + + FLG + + Sbjct: 341 NPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEI----ILSFLGKVQM 396 Query: 368 DVIRERLEREFGLELIATAPNVVYR---VEMEDGTEHIVTNPSEFPEGKIDKVHEPVVRA 424 +V L+ ++ +E+ P V+Y ++ + T HI P+ F I P+ Sbjct: 397 EVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPF-WASIGLSVSPLPLG 455 Query: 425 TVLA----------PSEFIGAIME 438 + + F A+ME Sbjct: 456 SGMQYESSVSLGYLNQSFQNAVME 479 Score = 35.6 bits (82), Expect = 6e-04 Identities = 14/81 (17%), Positives = 27/81 (33%), Gaps = 2/81 (2%) Query: 417 VHEPVVRATVLAPSEFIGAIMELCQNRRGTLLGMDYLSEDRVEIRYTLPLAEIVFDFFDQ 476 + EP + + AP E++ ++ L + V + +P I ++ Sbjct: 535 LLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQ-LKNNEVILSGEIPARCI-QEYRSD 592 Query: 477 LKSKTRGYASLDYEPTGEQSA 497 L T G + E G Sbjct: 593 LTFFTNGRSVCLTELKGYHVT 613
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.5 bits (126), Expect = 2e-10 Identities = 28/89 (31%), Positives = 46/89 (51%), Gaps = 5/89 (5%) Query: 1 MDRSLRVVLAEDSVLLREGLIGLLTRFGHEVVAAVGDAEALTAAVAEHGPDIVVTDVRMP 60 M + +++A+D +R L L+R G++V +A L +A D+VVTDV MP Sbjct: 1 MTGA-TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 PGFQDEGLHAAVRLREKQPALPVLVLSQY 89 + R+++ +P LPVLV+S Sbjct: 59 ---DENAFDLLPRIKKARPDLPVLVMSAQ 84
>PF06580#Sensor histidine kinase Length = 349 Score = 36.0 bits (83), Expect = 2e-04 Identities = 16/70 (22%), Positives = 31/70 (44%), Gaps = 6/70 (8%) Query: 358 RVAVSGGHAGGRMFLEIHDDGRGGA--STSGGGSGLTGLADRVSVL---DGRLSLSSPAG 412 ++ + G G + LE+ + G + G+GL + +R+ +L + ++ LS G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 413 GPTRLRVEIP 422 V IP Sbjct: 340 KVN-AMVLIP 348
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 28.9 bits (64), Expect = 0.048 Identities = 27/122 (22%), Positives = 41/122 (33%), Gaps = 15/122 (12%) Query: 12 LAIAVAAAVTTFPAVAQASTPAPVTASATPAAAVPAPTPRRDDFNGDGYPDVAFTAP--- 68 L I AAA A+T PV A+ T A ++ D P ++ A Sbjct: 5 LRIVSAAAAALLAVAPIAATAMPVNAATTINADSAINANTNAKYDVDVTPSISAIAAVAK 64 Query: 69 -------GATVGGTAKAGYVGVVYGSKSGLKTSTKQVFTQDSPGI---PDTAEAGDAFGS 118 ++ G+ A Y G Y + L + DS P EA A+ Sbjct: 65 SDTMPAIPGSLTGSISASYNGKSY--TANLPKDSGNATITDSNNNTVKPAELEADKAYTV 122 Query: 119 SM 120 ++ Sbjct: 123 TV 124
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 25.7 bits (56), Expect = 0.019 Identities = 11/43 (25%), Positives = 19/43 (44%), Gaps = 3/43 (6%) Query: 2 PSVLDRITEVLVSRFGVEPEEVTEDTTMRDLDLDS---LALVE 41 + I + + PE++T+ + D LDS + LVE Sbjct: 229 VFTCENIRKQIAELLQETPEDITDQEDLLDRGLDSVRIMTLVE 271
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.8 bits (173), Expect = 2e-17 Identities = 38/196 (19%), Positives = 69/196 (35%), Gaps = 17/196 (8%) Query: 3 TRTDAPTRREQILKEAARLFAERGFHGVGVDEIGAAVGISGPGLYRHFPGKDAMLAELLV 62 T+ +A R+ IL A RLF+++G + EI A G++ +Y HF K + +E+ Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 63 GISERLLAGGQLRVSEDAACRDGSPHALLDALIEGHIDFAL--DDRPL---ITLHDRELD 117 + E A G P ++L ++ ++ + + R L I H E Sbjct: 65 LSESNIGE----LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 118 RLRDADRKRVRQLQRQYVEVWVEVVR------ELYPDLPEHEARAAVHAVFGLLNSTPHL 171 ++ R L + + + ++ L DL A + L + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME--NW 178 Query: 172 GRPDAQPDRADTAALL 187 D A Sbjct: 179 LFAPQSFDLKKEARDY 194
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 116 bits (293), Expect = 4e-32 Identities = 57/213 (26%), Positives = 98/213 (46%), Gaps = 36/213 (16%) Query: 31 AIVLFTALVRLAVHPLSRAAARGQKARTRLQPQIAELRKKHGKNPERMQKALMELHKAEN 90 +I++ T +VR ++PL++A LQP+I +R++ G + +R+ + +M L+KAE Sbjct: 357 SIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEK 416 Query: 91 VSPLSGCLPSLLQMPAFFLLYHLFSSQTIDGHPNELLGHQLFGAPLGEHWHDALAHGGPF 150 V+PL GC P L+QMP F LY++ +L AP W L+ P+ Sbjct: 417 VNPLGGCFPLLIQMPIFLALYYMLMGSV-----------ELRQAPFA-LWIHDLSAQDPY 464 Query: 151 GAQGMVYLGLYAIVAVVATFNYRRTKAQMAANPVTPTTGPDGQPVPGMGMMTKLMPLMSF 210 + I+ V F ++ ++PTT D P + MP++ Sbjct: 465 --------YILPILMGVTMFFIQK---------MSPTTVTD----PMQQKIMTFMPVI-- 501 Query: 211 ATLFTVSVVPLAAALYVVTSTTWTAVERAFLYR 243 T+F + P LY + S T +++ +YR Sbjct: 502 FTVFFLW-FPSGLVLYYIVSNLVTIIQQQLIYR 533
>SECA#SecA protein signature. Length = 901 Score = 38.3 bits (89), Expect = 4e-05 Identities = 18/55 (32%), Positives = 23/55 (41%), Gaps = 6/55 (10%) Query: 278 EAFAASEATSPADPDLLPQYATTLAARGRAVPWP-PARSAPCWCGSGRTYRECHG 331 E A + S D D AA R+ PC CGSG+ Y++CHG Sbjct: 849 ERLAQMQQLSHQDDDS-----AAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHG 898
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 208 bits (530), Expect = 6e-62 Identities = 100/300 (33%), Positives = 141/300 (47%), Gaps = 33/300 (11%) Query: 215 QVGAPQAWKSGWTGKGVKVAVLDTGIDSTHPDFSGSIGESADFTQGNGAISGAASDGDGH 274 + AP W G+GVKVAVLDTG D+ HPD I +FT + D +GH Sbjct: 28 MIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGH 86 Query: 275 GTHVASTVAGDGTASDGRYRGMAPDAELLVGKVLDDNGGGQESWVLQGMEWAAA-RAPIV 333 GTHVA T+A + G+AP+A+LL+ KVL+ G GQ W++QG+ +A + I+ Sbjct: 87 GTHVAGTIAATENENGV--VGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDII 144 Query: 334 NISLSGAVTDGTDPLSQAVDNLSASHGTLFVAAAGNLGRPG----TVSTPGTADAALTVG 389 ++SL G + L +AV + L + AAGN G + PG + ++VG Sbjct: 145 SMSLGG--PEDVPELHEAVKKA-VASQILVMCAAGNEGDGDDRTDELGYPGCYNEVISVG 201 Query: 390 AVERDDALAGLSSQGPRLGDHAVKPDLTAPGIGIVAARAAGTDGDNTVNDRYTALSGTSM 449 A+ D + S+ + DL APG I++ +Y SGTSM Sbjct: 202 AINFDRHASEFSNSNN-------EVDLVAPGEDILST---------VPGGKYATFSGTSM 245 Query: 450 ATPHVAGAAALLAQA-----HPDWKGPQLKAALTSSAKPVAGQSAYEQGAGRLDVARATA 504 ATPHVAGA AL+ Q D P+L A L P+ S +G G L + Sbjct: 246 ATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGN-SPKMEGNGLLYLTAVEE 304
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.8 bits (74), Expect = 0.002 Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 2/64 (3%) Query: 111 PASPPPPSTQ-FPTVGAPTARPAGGYEPVEDHSDKTTPHPPSEADPAADPDPGPTAGPDP 169 P S P+ Q P V +P PA P E+ + P P + +P A+PD G P Sbjct: 317 PGSAEAPNAQPLPEV-SPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQPGTRP 375 Query: 170 EPTA 173 + A Sbjct: 376 DSPA 379 Score = 31.6 bits (71), Expect = 0.004 Identities = 18/63 (28%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 115 PPPSTQFPTVGAPTARPAGGYEPVEDHSDKTTPHPPSEADPAADPDP--GPTAGPDPEPT 172 P P + AP A+P P E+ ++ P+ P +PDP P A PD + Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370 Query: 173 AGS 175 G+ Sbjct: 371 PGT 373
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.0 bits (85), Expect = 6e-05 Identities = 22/97 (22%), Positives = 34/97 (35%), Gaps = 15/97 (15%) Query: 156 EPGKPGKPGKPSTPATPSAPGAPSGPAQPTAAPTSSAPEGTKPTSSTSSPSSPSSSPSTQ 215 + GK TP A G Q GTKP + + +P + Sbjct: 456 AKLRAGKASDSQTPDAKPGNKAVPGKGQA-------PQAGTKP--------NQNKAPMKE 500 Query: 216 SGGDLAETGSGAPVGLLSAAAAALVAAGGFLVIRRRK 252 + L TG A +AA + AG V++R++ Sbjct: 501 TKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKE 537 Score = 36.2 bits (83), Expect = 9e-05 Identities = 28/104 (26%), Positives = 41/104 (39%), Gaps = 17/104 (16%) Query: 153 KPDEPGKPGKPGKPSTPATPSAPGAPSGPAQPTAAPTSSAPE-GTKPTSSTSSPSSPSSS 211 K E + GK S TP A P AP+ GTKP + + + Sbjct: 450 KQAEELAKLRAGKASDSQTPDAK-----PGNKAVPGKGQAPQAGTKP--------NQNKA 496 Query: 212 PSTQSGGDLAETGSGA-PVGLLSAAAAALVAAGGFLVIRRRKAQ 254 P ++ L TG A P +AAA ++A G + +RK + Sbjct: 497 PMKETKRQLPSTGETANP--FFTAAALTVMATAGVAAVVKRKEE 538
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 34.2 bits (78), Expect = 3e-04 Identities = 14/49 (28%), Positives = 18/49 (36%), Gaps = 2/49 (4%) Query: 11 PPEEDPFLKKPQEPQGPREPQGPQGPQEPPSGSPYDSAPPPPPPPPPPP 59 P + + P EP EP+ P+ P P P P P P P Sbjct: 56 EPPQAV--QPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP 102 Score = 31.9 bits (72), Expect = 0.002 Identities = 14/59 (23%), Positives = 19/59 (32%) Query: 6 PTSGQPPEEDPFLKKPQEPQGPREPQGPQGPQEPPSGSPYDSAPPPPPPPPPPPYDSGP 64 P +PP+ +P P P+ P+E P P P P P P Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110 Score = 29.2 bits (65), Expect = 0.011 Identities = 16/61 (26%), Positives = 17/61 (27%) Query: 10 QPPEEDPFLKKPQEPQGPREPQGPQGPQEPPSGSPYDSAPPPPPPPPPPPYDSGPYGGGG 69 P P P PQ Q P EP + P P PP P P Sbjct: 38 LPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 97 Query: 70 P 70 P Sbjct: 98 P 98 Score = 28.0 bits (62), Expect = 0.028 Identities = 14/88 (15%), Positives = 26/88 (29%), Gaps = 9/88 (10%) Query: 4 DQPTSGQPPEEDPFLKKPQEPQGPREPQGPQGPQEPPSGSPYDSAPPPPPP--------- 54 + +PP+E P + + +P+ +P+ + QE P P P Sbjct: 74 EPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARL 133 Query: 55 PPPPPYDSGPYGGGGPYGGVDPLAGMPP 82 + G L+ P Sbjct: 134 TSSTATAATSKPVTSVASGPRALSRNQP 161
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 5e-04 Identities = 31/218 (14%), Positives = 58/218 (26%), Gaps = 16/218 (7%) Query: 132 QSEQSRPPSGPESGRDPRTPADRAPADRVPADRAPAVREPVDRTPAVREPVDRAPADPRR 191 Q++ PS E PA P++ V E + E ++ + Sbjct: 1004 QADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTA 1063 Query: 192 PASPDPTGGALPGMRDGRSQAPENTAAIRAVGRGGRPPAPRTTEQVPADG-----TMAIR 246 + A ++ A + + + + T V + T + Sbjct: 1064 QNR-EVAKEAKSNVKANTQTN--EVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ 1120 Query: 247 AIAPGAGAQPPAQAQAQA----PAPAQAQAPAPAQNRAPAPAQTPAS--APAELNSPRTP 300 + P Q Q++ PA+ P + T A PA+ S Sbjct: 1121 EVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE 1180 Query: 301 GP--GGGAASWAQQVHQLAQPDQAARPQPQQHQHQHQH 336 P + V + + A QP + Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNK 1218 Score = 30.4 bits (68), Expect = 0.023 Identities = 25/160 (15%), Positives = 44/160 (27%), Gaps = 30/160 (18%) Query: 45 QQGEPMPATASGAAAEPQPQPSAPAPAPVDETGPVFLDEEPYADNRPEPATAWQADASRQ 104 + E T+ + + Q + P P E P +EP + T Sbjct: 1118 KTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADT--------- 1168 Query: 105 TGFGGERDRRVSWGGAGQPGGQGEPGRQSEQSRPPSGPESGRDPRTPADRAPADRVPADR 164 QP + + + + P + PA P Sbjct: 1169 ----------------EQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVN 1212 Query: 165 APAVREPVDRTPAVREPVDRAPADPRRP--ASPDPTGGAL 202 + + +P +R R V P + +S D + AL Sbjct: 1213 SESSNKPKNRH---RRSVRSVPHNVEPATTSSNDRSTVAL 1249
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.002 Identities = 32/147 (21%), Positives = 62/147 (42%), Gaps = 14/147 (9%) Query: 49 VVAFCATLPIVVSALIGGPVIDRVGRRRVSVASDLVCGAAVSAIPVLHYA---DALAFWM 105 V+ F T+ +++ IGG ++DR G V L G ++ L + + +++M Sbjct: 297 VIIFPGTMSVIIFGYIGGILVDRRGPLYV-----LNIGVTFLSVSFLTASFLLETTSWFM 351 Query: 106 LCALMALSGLLHTPGNTARYVLVPDLAEHAGTTLARAASLFDAVSRGARMVGAALAGVLI 165 ++ + G L ++ L + SL + S + G A+ G L+ Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQ---QEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408 Query: 166 ALVGAETVLLL---DAATFLTSALLIA 189 ++ + LL D +T+L S LL+ Sbjct: 409 SIPLLDQRLLPMEVDQSTYLYSNLLLL 435
>INTIMIN#Intimin signature. Length = 939 Score = 32.7 bits (74), Expect = 0.006 Identities = 41/204 (20%), Positives = 59/204 (28%), Gaps = 16/204 (7%) Query: 320 LDASGATLDDTAVYVKSTADGT--FSADFTVSDPAIAAIQVDEG---NDPATVLTTPFAV 374 +D G T D TA + ADGT + TV +A V VL+ A Sbjct: 555 VDQVGVT-DFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSAN 613 Query: 375 TDASATLSAGAAKVKPGGTITLSGGDWPTGTTPAAALCAADGSACDSARISGSTLRINAD 434 T+ S + KPG + + T A A+ D + I A+ Sbjct: 614 TNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVAN 673 Query: 435 GTLAGTVTVAGSTPRAVYALQVTAGGAQALTPLTVAPTFVVLTPSAGPKGTAVTVLGQGF 494 G A T TV + + + + T + T G A L Sbjct: 674 GQDAITYTV-----KVMKGDKPVSNQEVTFTTTLGKLS--NSTEKTDTNGYAKVTLTSTT 726 Query: 495 AKVATVSIVGLRADGSQTSDPVRT 518 + VS R Sbjct: 727 PGKSLVSA---RVSDVAVDVKAPE 747
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 71.8 bits (176), Expect = 1e-15 Identities = 76/396 (19%), Positives = 144/396 (36%), Gaps = 35/396 (8%) Query: 54 VVFLIAFEATAVGTAMPVAARELHGIP-LYAFAFSAYFTTSLFAMVLSGQWADRRGPLGP 112 + F + ++P A + + P + +A+ T + G+ +D+ G Sbjct: 22 LSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRL 81 Query: 113 LATGISAFGVGLLLSGTAGSMW-MFIAGRAVQGLGGGLVIVALYVVISRAYPEHLRPSIM 171 L GI G ++ S + + I R +QG G + VV++R P+ R Sbjct: 82 LLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAF 141 Query: 172 AAFAASWVIPSVVGPLAAGSVTEHLGWRWVFIGIPVLVV-FPLALALPAIRRRASGPADP 230 + + VGP G + ++ W ++ + + ++ P + L R G D Sbjct: 142 GLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFD- 200 Query: 231 TAPVEPYDRRRILLALGISLGAGLLQYAGQERNWFALLPAVVGFGLLVPAVRG----LLP 286 I + +S+G + L+ +V+ F + V +R + Sbjct: 201 -----------IKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 287 PGTGRAARGLPSVVLLRGVAAGSFIAAESFVPLMLVTQRGLSPTMAGL------SLAAGG 340 PG G+ VL G+ G+ S VP M+ LS G +++ Sbjct: 250 PGLGK-NIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVII 308 Query: 341 ATWALGSYVQSRPRLEPYRERLMVGGMVLVAAAIAAAPSVLIDWVPVW-TVAVAWAFGCF 399 + G V R L ++ G+ ++ + A S L++ + T+ + + G Sbjct: 309 FGYIGGILVDRRGPL-----YVLNIGVTFLSVSFLTA-SFLLETTSWFMTIIIVFVLGGL 362 Query: 400 GMGMVIASTSVLLLKLSAPEEAGANSAALQISDGLS 435 + ST V +EAGA + L + LS Sbjct: 363 SFTKTVISTIV--SSSLKQQEAGAGMSLLNFTSFLS 396
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 28.2 bits (62), Expect = 0.033 Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 4/51 (7%) Query: 62 LREIRAVLDSQVDQVAVLREHHRRLLREHDRLETLVRTVERTIAELEEGKD 112 LR+ R++ D V VLRE LLR D E + + +E + +EE D Sbjct: 112 LRQARSLFPDPSDLVLVLRE----LLRRKDLEEIVRKKLESLLKHVEEQTD 158
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 32.4 bits (73), Expect = 0.007 Identities = 23/89 (25%), Positives = 43/89 (48%), Gaps = 1/89 (1%) Query: 12 TAVTQWTEMIGKLTSLQTDASAMKTKADKSTWKGENATVTKEFVTKTAKEFSDAVTEAES 71 ++ Q T ++GKL +L D S + ++ + W+ + KE + +KEF A+ EA+ Sbjct: 80 SSEGQLTLLLGKLMTLLGDVSLSQLESRLAVWQAMIES-QKEMGIQVSKEFQTALGEAQE 138 Query: 72 VRDLLKDAHALLKDAHALLKSAHDDLKDA 100 DL + + A ++ +A L A Sbjct: 139 ATDLYEASIKKTDTAKSVYDAATKKLTQA 167
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 30.5 bits (68), Expect = 0.027 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 9/98 (9%) Query: 115 VRAVGAALCGALGQLHSSEVVHRDLKPSNVMLS-AYG-PKVIDFGIARALGDDRLTRTGT 172 ++ + L L + VVH D+KP NV+ A G P VID G+ G+ Sbjct: 247 IKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQ------P 300 Query: 173 AAGTPAYMSPEQASGQ-EQTPAGDVFALAGILVFAATG 209 T ++ +PE G + DVF + L+ G Sbjct: 301 KGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 36.6 bits (84), Expect = 1e-04 Identities = 29/100 (29%), Positives = 47/100 (47%), Gaps = 13/100 (13%) Query: 114 VRALAADLARALGDIHAAGLVHRDVKPANIMM--TSDGPRVIDFGIARPEHGLTLTTTGE 171 ++ +A L + AG+VH D+KP N++ S P VID G+ + +GE Sbjct: 247 IKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLH--------SRSGE 298 Query: 172 IP--VTPGYGAPEQVLGQR-VGPAADVFSLGAVLVYAATG 208 P T + APE +G +DVF + + L++ G Sbjct: 299 QPKGFTESFKAPELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 131 bits (332), Expect = 1e-37 Identities = 79/284 (27%), Positives = 119/284 (41%), Gaps = 32/284 (11%) Query: 1 MQAETMWRTSTGEGVTVAVIDTGV-REVPELAGQLLEGKDFTDGVTGEHDEA------GT 53 +QA +W + G GV VAV+DTG + P+L +++ G++FTD G+ + GT Sbjct: 29 IQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGT 88 Query: 54 TAAAVIAGTGKGAGGKESAYGLAPGAKILPLKVSDGSEAPQSGERSIAINSDLAPAIRYA 113 A IA T G G+AP A +L +KV + + Q + I YA Sbjct: 89 HVAGTIAATENENGV----VGVAPEADLLIIKVLNKQGSGQY--------DWIIQGIYYA 136 Query: 114 ADSEAKVISISVTASLSIGGAVDEAVKCALSKGKLVFAAVG---DSEFPERPVQNPAAIP 170 + + +IS+S+ + EAVK A++ LV A G D + + P Sbjct: 137 IEQKVDIISMSLGGPED-VPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGYPGCYN 195 Query: 171 GVTGVAALGKDLAALKSSAVGPEVTLSAAGEDVLSACAEPEGLCTSSGSAVATAVAAASA 230 V V A+ D A + S EV L A GED+LS T SG+++AT A + Sbjct: 196 EVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPG-GKYATFSGTSMATPHVAGAL 254 Query: 231 ALIWAKYP-----DWTNYQVLRVMVNTVGGPTSGAVRNNYIGYG 269 ALI D T ++ ++ G G Sbjct: 255 ALIKQLANASFERDLTEPELYAQLIKRT---IPLGNSPKMEGNG 295
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 183 bits (467), Expect = 3e-56 Identities = 87/293 (29%), Positives = 133/293 (45%), Gaps = 26/293 (8%) Query: 38 QWYLDAMQAEQMWKSSTGENVTVAVIDSGVDASIPDLRGRVLKGKDLAAASPGDE--HTD 95 ++ +QA +W + G V VAV+D+G DA PDL+ R++ G++ GD D Sbjct: 23 PRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKD 82 Query: 96 YDNHGTGMASIIAGTGNVRGGGGSFGLAPGVKILPIRLRDTTGKVNGATGNKYLNEDLSV 155 Y+ HGT +A IA T N G G+AP +L I++ + G G + + Sbjct: 83 YNGHGTHVAGTIAATEN---ENGVVGVAPEADLLIIKVLNKQGS--GQY------DWIIQ 131 Query: 156 AIRFAVDHGAKIINASVGDSIGGSQQLTDSVKYALDKGALIFAAVGN---SADEGNLIEY 212 I +A++ II+ S+G +L ++VK A+ L+ A GN D + + Y Sbjct: 132 GIYYAIEQKVDIISMSLGGP-EDVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDELGY 190 Query: 213 PAGTPGVVGVGAIGKDLHKADFSQWGPQVDLSAPGVDMVHGCSGGTKLCRTSGTSDAAAI 272 P V+ VGAI D H ++FS +VDL APG D++ GG K SGTS A Sbjct: 191 PGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGG-KYATFSGTSMATPH 249 Query: 273 VSASAALIWSK-----HLDWTNNQVLRVLLNTVGAPTSGALRNDYVGYGVVRP 320 V+ + ALI D T ++ L+ G G++ Sbjct: 250 VAGALALIKQLANASFERDLTEPELYAQLIKRT---IPLGNSPKMEGNGLLYL 299
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 39.0 bits (90), Expect = 6e-05 Identities = 29/92 (31%), Positives = 41/92 (44%), Gaps = 19/92 (20%) Query: 356 VDLAQVPAPDTVQAPDTVQAPDTVPAADTVPAPDTVPAADTPAEHPVEATPEHHPA---- 411 VD+ +P PD P + +AP+ P + PA + PA +P P +P Sbjct: 305 VDVQVIPRPDL--TPGSAEAPNAQPLPEVSPA-------ENPANNP---APNENPGTRPN 352 Query: 412 -EPPAGTAPDSEPDT--APDTAPDAPPLDTPP 440 EP PD+ PDT P T PD+P + P Sbjct: 353 PEPDPDLNPDANPDTDGQPGTRPDSPAVPDRP 384
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 92.1 bits (229), Expect = 2e-28 Identities = 39/90 (43%), Positives = 54/90 (60%), Gaps = 1/90 (1%) Query: 2 NRSELVAALADRAEVTRKDADAVLAALAETVGEIVAKGDEKVTIPGFLTFERTHRAARTA 61 N+ +L+A +A+ E+T+KD+ A + A+ V +AKG+ KV + GF FE RAAR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGE-KVQLIGFGNFEVRERAARKG 61 Query: 62 RNPQTGDPINIPAGYSVKVSAGSKLKEAAK 91 RNPQTG+ I I A AG LK+A K Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.7 bits (69), Expect = 0.006 Identities = 13/51 (25%), Positives = 16/51 (31%) Query: 140 PAVLRPTPQPPPREPAAEPHPASSEAPQPPASQGTPEPRPALVFVPAPTAP 190 P P P EP EP P + P P+P+P P Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQ 107
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 30.2 bits (68), Expect = 0.013 Identities = 14/60 (23%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 242 AMATFVPKFVLPAAVAWTLAADENMSAHGLHHLDTTAQAMKIHAAF--EAANPRPMATVA 299 A F + +P+A W + +E + + L + K+ + F + + RPM TV+ Sbjct: 207 AFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVS 266
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 5e-06 Identities = 20/81 (24%), Positives = 31/81 (38%), Gaps = 24/81 (29%) Query: 321 LIENSLMHG------GGTVALRTRVTGNQAVIEVTDEGPGVPPDLGARIFERTISGRNST 374 L+EN + HG GG + L+ +EV + G + + ST Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK-----------NTKEST 311 Query: 375 GIGLAVARDLAEADGGRLELL 395 G GL R+ RL++L Sbjct: 312 GTGLQNVRE-------RLQML 325
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 98.4 bits (245), Expect = 5e-26 Identities = 38/128 (29%), Positives = 64/128 (50%) Query: 2 TRVLLAEDDASISEPLARALRREGYEVEVREDGPTALDAGLQGGIDLVVLDLGLPGMDGL 61 +L+A+DDA+I L +AL R GY+V + + T G DLVV D+ +P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVARRLRAEGHTAPILVLTARADEVDTVVGLDAGADDYVTKPFRLAELLARVRALLRRGA 121 ++ R++ P+LV++A+ + + + GA DY+ KPF L EL+ + L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 TEPAPQPA 129 P+ Sbjct: 124 RRPSKLED 131
>cloacin#Cloacin signature. Length = 551 Score = 30.5 bits (68), Expect = 0.015 Identities = 16/64 (25%), Positives = 25/64 (39%) Query: 169 GGGSTTAGGTTTGSTTGSTTAGGTTTAGGTTTGSTTAGGTTTAGGTTAGGTTAAGGTTSG 228 G +T+G G T G + +G ++ + GG+ + G GG Sbjct: 11 TGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGN 70 Query: 229 SGGG 232 SGGG Sbjct: 71 SGGG 74
>PF06776#Invasion associated locus B Length = 214 Score = 25.7 bits (56), Expect = 0.028 Identities = 10/31 (32%), Positives = 13/31 (41%), Gaps = 1/31 (3%) Query: 1 MSLTTDGEPPGPVRFYLACDRSGCRARAVFD 31 + L D G F + C +GC A V D Sbjct: 143 LGLKLDNVDVGRAGF-VRCLPNGCVAEVVMD 172
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 30.8 bits (69), Expect = 0.015 Identities = 14/89 (15%), Positives = 27/89 (30%) Query: 200 DAKAATSEDESAPDADADADTDAVAGGDASEPATPADGASDKATASNDADAADEPSDDAS 259 D +E D + + P + A+ + A + Sbjct: 83 DELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKP 142 Query: 260 EDAEDSEDAAASEADAANTADADSKADKP 288 E + A++A+ A + S +DKP Sbjct: 143 ETTPEPVVKPAADAEPKTAAPSPSSSDKP 171
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 89.3 bits (221), Expect = 2e-23 Identities = 70/259 (27%), Positives = 106/259 (40%), Gaps = 13/259 (5%) Query: 3 LAGKTVIVSGVGAGLGHQVAATVVRDGGSAVLGARTAANLAKSASEIDPEGRHTAHLATD 62 + GK ++G G+G VA T+ G L K S + E RH D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 63 ITDEAQCEALAALALERFGRIDAVVHVAAWDSYFGGIEDADFATWRSVIDVNLLGTLRMT 122 + D A + + A G ID +V+VA G I W + VN G + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 123 RACLPGLK-ERGGSVVVIGTQSSVAAPSQVQQAAYAASKGALTSAMYSMAREFGPHRIRV 181 R+ + R GS+V +G S+ A + AAYA+SK A + E + IR Sbjct: 125 RSVSKYMMDRRSGSIVTVG--SNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 182 NTVLPGWMWGPPVQAYVRFTAHTEGVPEAEVLGRLTER----MALPDLATDGDVAEAAAF 237 N V PG + ++++ + +V+ E + L LA D+A+A F Sbjct: 183 NIVSPG-----STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLF 237 Query: 238 LASDRARAITGQSLLVNAG 256 L S +A IT +L V+ G Sbjct: 238 LVSGQAGHITMHNLCVDGG 256
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 52.8 bits (127), Expect = 3e-09 Identities = 32/134 (23%), Positives = 53/134 (39%), Gaps = 23/134 (17%) Query: 2 LDHLIRGATVVDGTGGPSYPADIGIRDGRIAVIAE---PGTL---------AEEAVTTED 49 +D +I A ++D G ADIG++DGRIA I + P E + E Sbjct: 68 VDTVITNALILDHWG--IVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGE- 124 Query: 50 ATGLVLAPGFVDPHTHY-DAQLFWDPYATPSMNHGVTTVAGGNCGFTLAPLHPERPEDAD 108 G ++ G +D H H+ Q + ++ G+T + GG G L Sbjct: 125 --GKIVTAGGMDSHIHFICPQQIEE-----ALMSGLTCMLGGGTGPAHGTLATTCTPGPW 177 Query: 109 YTRRMMSRVEGMAL 122 + RM+ + + Sbjct: 178 HIARMIEAADAFPM 191
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 132 bits (332), Expect = 2e-39 Identities = 80/258 (31%), Positives = 121/258 (46%), Gaps = 5/258 (1%) Query: 4 LDGRVVLISGAARGQGEQEARLFAAEGARVVIADVLDEQGEALAKELGEGVARFVH---L 60 ++G++ I+GAA+G GE AR A++GA + D E+ E + L + AR Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSL-KAEARHAEAFPA 64 Query: 61 DVSREGEWQAAVAAAKDAFGRIDGLVNNAGILRFNELVTTPLEEFQQVVQVNQVGAFLGI 120 DV A + G ID LVN AG+LR + + EE++ VN G F Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 121 KSVAPEIEAAGGGTIVNTASYTGLTGMAFVGAYAATKHAVLGLTKVAAVELAAKGIRVNA 180 +SV+ + G+IV S + AYA++K A + TK +ELA IR N Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 181 VCPGAVDTAMTNPAALDPTADPEESGAAVAELYRKLVPLGRIGQPEEVAALALFLTSDDS 240 V PG+ +T M D E+ E ++ +PL ++ +P ++A LFL S + Sbjct: 185 VSPGSTETDMQWSLWADENGA-EQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 241 SYITGQPFVIDGGWLAGV 258 +IT +DGG GV Sbjct: 244 GHITMHNLCVDGGATLGV 261
>cloacin#Cloacin signature. Length = 551 Score = 29.7 bits (66), Expect = 0.013 Identities = 22/84 (26%), Positives = 30/84 (35%), Gaps = 4/84 (4%) Query: 76 TGATGASGTNGADGATGPV--GPTGATGASGTNGADGATGPVGPTGATGASGTNGADGAT 133 +G G GA +G + GPTG G + G + P G G SG+ G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWG--GGSGSGIHWGGG 59 Query: 134 GPVGPTGATGAAGTNGADGATGAT 157 G G G +G G + Sbjct: 60 SGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 28.5 bits (63), Expect = 0.027 Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 4/92 (4%) Query: 97 TGATGASGTNGADGATGPV--GPTGATGASGTNGADGATGPVGPTGATGAAGTNGADGAT 154 +G G GA +G + GPTG G + G + P G G +G+ G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWG--GGSGSGIHWGGG 59 Query: 155 GATGPTGATGPAGPVGPSQQANSNVTSVPAGG 186 G G G +G + S V + A G Sbjct: 60 SGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFG 91
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.9 bits (212), Expect = 4e-21 Identities = 54/193 (27%), Positives = 83/193 (43%), Gaps = 7/193 (3%) Query: 199 AAPLTGRTALVTGAARGIGASVASVLARDGAQVICLDIPRSADELKRTAERLGA---TAL 255 A + G+ A +TGAA+GIG +VA LA GA + +D E ++ + A A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 256 PLDITADDAADRIA---AASPDGLDILVHNAGITRDRRLANMPPDRWASVIEVNLGSVLR 312 P D+ A D I +DILV+ AG+ R + ++ + W + VN V Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 313 TTDALLMSGTVNRGGRIVATASIAGIAGNNGQTNYAAGKAGIIGLVRSLAPRAAADHGVT 372 + ++ R G IV S YA+ KA + + L A++ + Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLG-LELAEYNIR 181 Query: 373 VNAVAPGFIETKM 385 N V+PG ET M Sbjct: 182 CNIVSPGSTETDM 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 73.5 bits (180), Expect = 3e-18 Identities = 31/204 (15%), Positives = 62/204 (30%), Gaps = 14/204 (6%) Query: 1 MPRAVREQ------QMMDAAVRTFGQRGYRAASMDEIAELAGVSKPLVYLYLNSKEELFT 54 M R +++ ++D A+R F Q+G + S+ EIA+ AGV++ +Y + K +LF+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 55 ACIQREAKALVAAVRSGVEPELPADRQLWAGLRAFFTHTAKNPDGW----AVLHRQARTH 110 + + + + + + ++ + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 111 GEPFATEVMVMRDEIVAFVTGLIGAAAREAHRDPAL-PDRDVAGLAQALVGAAESL-AGW 168 GE V + + I + L D A + G L W Sbjct: 121 GE--MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENW 178 Query: 169 ANDTPGVSAKEAAATLMNFAWAGL 192 K+ A + Sbjct: 179 LFAPQSFDLKKEARDYVAILLEMY 202
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 857 bits (2215), Expect = 0.0 Identities = 325/625 (52%), Positives = 419/625 (67%), Gaps = 60/625 (9%) Query: 20 LTRAAYADRFGPTVRDRIRLADTELRIEIEDDWAGGPGRSGNEMVFGGGKVIRESMGQSI 79 ++RAAYA+ FGPTV D++RLADTEL IE+E D+ G E+ FGGGKVIR+ MGQS Sbjct: 5 MSRAAYANMFGPTVGDKVRLADTELFIEVEKDFT----THGEEVKFGGGKVIRDGMGQSQ 60 Query: 80 APRDPAGADGPGGPGESDGGEVVMPPDTVITGAVVLDHWGIVKADVAIRDGRITALGKAY 139 R+ DTVIT A++LDHWGIVKAD+ ++DGRI A+GKA Sbjct: 61 VTREGG------------------AVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAG 102 Query: 140 NDETMDPLHEGAGNHNDVGPIPTDFVIGPDTEVIAGNGKILTAGGVDTHVHFICPEQVGE 199 N + + ++GP TEVIAG GKI+TAGG+D+H+HFICP+Q+ E Sbjct: 103 NPDMQPGV---------------TIIVGPGTEVIAGEGKIVTAGGMDSHIHFICPQQIEE 147 Query: 200 ALSAGVTTLIGGGTGPAEGSTATTVTPGSWHLARTFEALDSFPVNVGLLGKGATMSEKSM 259 AL +G+T ++GGGTGPA G+ ATT TPG WH+AR EA D+FP+N+ GKG ++ Sbjct: 148 ALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASLPGAL 207 Query: 260 YDQVDAGVIGFKIHEDWGATPAVIKKCLEVCRQTGVQLALHADSLNEAGFVDDTIRAIDG 319 + V G K+HEDWG TPA I CL V + VQ+ +H D+LNE+GFV+DTI AI G Sbjct: 208 VEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDVQVMIHTDTLNESGFVEDTIAAIKG 267 Query: 320 HSIHVFHVEGAGGGHAPDMIKMVHEGNVLPASTNPTRPLTINTVKEHFDMVMVCHHLNPK 379 +IH +H EGAGGGHAPD+I++ + NV+P+STNPTRP T+NT+ EH DM+MVCHHL+P Sbjct: 268 RTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPTRPYTVNTLAEHLDMLMVCHHLSPT 327 Query: 380 IKEDLAFADSRIRPSTMAAEDILHDLGAISIMSSDAQAMGRIGEMIMRTWQTAHVMKVRR 439 I ED+AFA+SRIR T+AAEDILHD+GA SI+SSD+QAMGR+GE+ +RTWQTA MK +R Sbjct: 328 IPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDSQAMGRVGEVAIRTWQTADKMKRQR 387 Query: 440 GFLEGDKLPEGEQPTGDKGSDNRRARRYVAKYTINPAIAQGVDAVVGSVEPGKLADLVLW 499 G L+ + +DN R +RY+AKYTINPAIA G+ +GS+E GK ADLVLW Sbjct: 388 GRLKEET----------GDNDNFRVKRYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLW 437 Query: 500 EPKFFGVKPHQVIKGGQIAYAQVGDANASIPTPQPVLPRAMWGATGLAPRATSFNFVTQR 559 P FFGVKP V+ GG IA A +GD NASIPTPQPV R M+GA G + +S FV+Q Sbjct: 438 NPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYGRSRTNSSVTFVSQA 497 Query: 560 AIDNGLPERLALGKQFKAISSTR-DVRKADMKENDATPDVRIDPDTFEVIAGGAKVEDVT 618 ++D GL RL + K+ A+ +TR + KA M N TP + +DP+T+EV A G ++ Sbjct: 498 SLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPETYEVRADG----ELL 553 Query: 619 TCIEGQIVERNYPRELPMAQRYFLF 643 TC LPMAQRYFLF Sbjct: 554 TC--------EPATVLPMAQRYFLF 570
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.004 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 209 VLLYGPPGTGKTLLARAV---AGEAGVPFYS-----ISGSDFVEMFVGV------GASRV 254 +++ G GTGK L+ARA+ PF + I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 255 RD-LFEQAKANAPAIVFVDEID 275 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEG---GTLFLDEIG 241
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 50.4 bits (120), Expect = 4e-09 Identities = 29/205 (14%), Positives = 65/205 (31%), Gaps = 36/205 (17%) Query: 203 SIVKVVGTAPSCGKVLEGTGFVFSDRRVMTNAHVVGGVDEPTVQI-----------GGQG 251 + + AP+ + +G V ++TN HVV + G Sbjct: 89 PVTYIQVEAPTGTFI--ASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNG 146 Query: 252 RLYDAKVVLYDWQRDIAVLDVPDLD--------AKPLKFTDTDHDAGTGNSAIVAGFPEN 303 ++ Y + D+A++ + KP ++ + + V G+P + Sbjct: 147 GFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNA-ETQVNQNITVTGYPGD 205 Query: 304 GSYDVRAARVRGRI-DADGPDIYHRGTVRRDVYSLFATVRQGNSGGPLLTPDGKVYGVVF 362 +G+I G + + GNSG P+ +V G+ + Sbjct: 206 KPVATMWES-KGKITYLKGEAM-----------QYDLSTTGGNSGSPVFNEKNEVIGIHW 253 Query: 363 AKSLDDPDTGYALTADEIRQDIAHG 387 ++ + + + +R + Sbjct: 254 GGVPNEFNGAVFIN-ENVRNFLKQN 277
>BACINVASINC#Salmonella/Shigella invasin protein C signature. Length = 409 Score = 30.2 bits (67), Expect = 0.016 Identities = 31/139 (22%), Positives = 60/139 (43%), Gaps = 17/139 (12%) Query: 274 ERDALREAAYFVERLAAEEMPLAGLVLNRVHGSDAARLSAELALAAAENLDGVGIVDQTA 333 ER AL+ A +++L E + N ++G ++ +L AE GV + Sbjct: 202 ERGALKHNAAKIDKLTTESHSIK----NVLNGQNSVKLGAE----------GVDSLKSLN 247 Query: 334 G-KAGLRDPADWSVVSPEAVADPDPSEHEDTED--REPDPEPAPEVATRTETVTEDASVE 390 K G + + + ++ A +E ++ ++ PE ++ R E+V D +E Sbjct: 248 MKKTGTDATKNLNDATLKSNAGTSATESLGIKNSNKQISPEHQAILSKRLESVESDIRLE 307 Query: 391 QLTAGLLRLHAERMQVVAR 409 Q T + R+ A +MQ+ Sbjct: 308 QNTMDMTRIDARKMQMTGD 326
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 28.8 bits (64), Expect = 0.031 Identities = 35/123 (28%), Positives = 47/123 (38%), Gaps = 3/123 (2%) Query: 280 SVSPYGGVRAVVLLPDELLTGDAPAPPTPLAAPGGHDADVSALPRRQAPTPPPTPLFPPA 339 SV +G V A +L + PAP P++ AD L QA PPP P+ P Sbjct: 16 SVCIHGAVVAGLLYTSVHQVIELPAPAQPISVTMVTPAD---LEPPQAVQPPPEPVVEPE 72 Query: 340 AHPAPAPQPTGSFTTAGGLPKRRRKSPVSVVPSTEPGPVRSNEETASRLGAFQRGTRTGR 399 P P P+P PK + K V + P R + SR + T R Sbjct: 73 PEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPAR 132 Query: 400 DTT 402 T+ Sbjct: 133 LTS 135
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.8 bits (150), Expect = 3e-13 Identities = 29/120 (24%), Positives = 48/120 (40%), Gaps = 5/120 (4%) Query: 4 TATRIVVVDDHEVVRAGFAGLLDTQPDFTVVGTASDGAEAVRVCAQQRPDVVLMDVRMPG 63 T I+V DD +R L ++ + V S+ A R A D+V+ DV MP Sbjct: 2 TGATILVADDDAAIRTVLNQAL-SRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 64 TDGIEATAQIRAATPDGGGPRILILTTFDLDEHVYDALAAGAGGFLLKDVTAEHLFDAVR 123 + + +I+ A PD +L+++ + A GA +L K L + Sbjct: 60 ENAFDLLPRIKKARPD---LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 5e-04 Identities = 18/91 (19%), Positives = 37/91 (40%), Gaps = 9/91 (9%) Query: 306 IVQEALTNARRHA-----PGAAVDVELRYAPQTLDLRIRDNGPGPDRSGARASGHGLLGM 360 +VQ + N +H G + ++ T+ L + + G ++ ++G GL + Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNV 318 Query: 361 RERVAAVGGE---LSAGPAPGGGFLIEVRLP 388 RER+ + G + G + V +P Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>cloacin#Cloacin signature. Length = 551 Score = 31.6 bits (71), Expect = 0.018 Identities = 24/46 (52%), Positives = 26/46 (56%), Gaps = 9/46 (19%) Query: 279 NGSGSGTGIERGHGGGSGHGNGTGIANSNGA-------LSVARPVA 317 G GSG+GI GGGSGHGNG G NS G +VA PVA Sbjct: 46 WGGGSGSGI--HWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVA 89
>PF01540#Adhesin lipoprotein Length = 475 Score = 30.9 bits (69), Expect = 0.005 Identities = 16/47 (34%), Positives = 23/47 (48%) Query: 9 TILAAATTAVLALALTACGGDDSGTKSAGPASDAAAAAASTDATDAK 55 T+ A TAVL +A +C D K+ +DAA A+ A + K Sbjct: 10 TLCGIAATAVLPIATISCNDDKLAEKNGKEKADAALKQANALAEELK 56
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.023 Identities = 20/142 (14%), Positives = 39/142 (27%), Gaps = 23/142 (16%) Query: 9 LFAVGDDYWIEDADGRKVFLVDGKAMRVRDTFELKDAQGRILVEIRQKLLSLRDTMLIER 68 L+ G+ Y+ D F + + V + + + R+ + Sbjct: 736 LYLAGERYFPSPEDEEIYFRPEQELRLVETGVQGR----LWALLTREGAPAAEGA----- 786 Query: 69 DGEQLARIKRKRLSLLRNHYRVTLVDGTELDVS-------GKILDREFAIDYDGELLAQI 121 Q + + LV D G++ D ++ Sbjct: 787 --AQKGYSVNTTFVTIAD-----LVQALGADPGKSSPMLEGQVRDWLNENGWEYLRETSG 839 Query: 122 SRRWLTVRDTYGIDVVREDADA 143 RR +R V+ ED +A Sbjct: 840 QRRRGYMRPQVWPPVIAEDKEA 861
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 42.1 bits (99), Expect = 3e-06 Identities = 63/344 (18%), Positives = 104/344 (30%), Gaps = 33/344 (9%) Query: 53 FHVNASALSTFSILQLLVYAGMQIPV----GLMVDRLGTKKVLTLGAVLFTLGQLGFALS 108 + + + IL L +YA MQ G + DR G + VL + + A + Sbjct: 35 LVHSNDVTAHYGIL-LALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 109 PSYGMALASRALLGCGDAMTFISVLRLGARWFPARRGPLIGQVAALFGMAGNLVSTLFIA 168 P + R + G A T A + A FG +A Sbjct: 94 PFLWVLYIGRIVAGITGA-TGAVAGAYIADITD------GDERARHFGFMSACFGFGMVA 146 Query: 169 RALHG-----FGWTTTFVGTSAAGVLVLVPLLLFLKDHPEGHEPPPVEHAGAAYVRKQIA 223 + G F F +A L + L + +G P A + A Sbjct: 147 GPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWA 206 Query: 224 ASWREPGTRLGMWVHFTTQFPAMVFLLLWGLPFLVEAQGLSRSTAGELLTLVVLSNMAFG 283 M V F Q V LW + F + +T G L + + Sbjct: 207 RGMT--VVAALMAVFFIMQLVGQVPAALWVI-FGEDRFHWDATTIGISLAAFGILHSLAQ 263 Query: 284 LVYGQIIARHHEARAPLALG-TVTVTALLWASTIFYPGDRAPMWLLIVLCVVLGVCGPAS 342 + +A R L LG T + + R M I++ + G G + Sbjct: 264 AMITGPVAARLGERRALMLGMIADGTGYILLAFA----TRGWMAFPIMVLLASGGIGMPA 319 Query: 343 MIGFDFARPANPPERQGTASG----IVNMGGFIASM--TTLFAV 380 + + ERQG G + ++ + + T ++A Sbjct: 320 LQAMLSRQVDE--ERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 39.2 bits (91), Expect = 2e-05 Identities = 25/127 (19%), Positives = 35/127 (27%) Query: 289 PAGPIAAPRTASQDAQPVQTDQSAQQPYTQPPVPMSETGSFHLPPPPRQPTPLPHPAQPA 348 PA PI+ A D +P Q Q +P +P P P P P Sbjct: 46 PAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKP 105 Query: 349 TPPTPVPAHAASPFPAPDPSQAPTAAVQHEAALTRAYTAGQPQVPAPGSGVSPHLSAAVP 408 P V P +P + TA + + LS P Sbjct: 106 KPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQP 165 Query: 409 VHAPRTR 415 + R + Sbjct: 166 QYPARAQ 172
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.005 Identities = 15/61 (24%), Positives = 21/61 (34%), Gaps = 7/61 (11%) Query: 12 EGYATGPLPGEREPAPGQASGPYHPPQAYPSPAGGTQGGAQGAAAAQAARR-PRTGARTT 70 G A+ + +P G PQA GT+ A + R+ P TG Sbjct: 460 AGKASDSQTPDAKPGNKAVPGKGQAPQA------GTKPNQNKAPMKETKRQLPSTGETAN 513 Query: 71 P 71 P Sbjct: 514 P 514
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.028 Identities = 13/48 (27%), Positives = 17/48 (35%), Gaps = 3/48 (6%) Query: 268 VIGASNRFAHAAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGHYA 315 ++G S V L I GESG GK + A+ H Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDL--TLMITGESGTGKELVARAL-HDY 183
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 236 bits (604), Expect = 1e-74 Identities = 75/250 (30%), Positives = 113/250 (45%), Gaps = 48/250 (19%) Query: 6 SLFSFITWPVSWVIVQFHTLYGAIFGDDTGWAWGLSIVSLVVLIRICLIPLFVKQIKSTR 65 FI+ P+ ++ H+ G WG SI+ + ++R + PL Q S Sbjct: 331 GWLWFISQPLFKLLKWIHSFVGN---------WGFSIIIITFIVRGIMYPLTKAQYTSMA 381 Query: 66 NMQVLQPKMKAIQERYKSDKQRQSEEMMKLYKETGTNPLSSCLPILAQSPFFFALYHVLS 125 M++LQPK++A++ER DKQR S+EMM LYK NPL C P+L Q P F ALY++L Sbjct: 382 KMRMLQPKIQAMRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLM 441 Query: 126 AIASGKTIGVIDQPLLDSARQAHIFGAPLAAKFMDSEAKVQALGASLLDVRVVTAIMIVM 185 + AP A D A+ I+ ++ Sbjct: 442 -------------------GSVELRQAPFALWIHDLSAQDPYY------------ILPIL 470 Query: 186 MSASQFFTQRQLMTKNVDLTVKTPYMQQQKMLMYIFPVIFAVMGINFPVGVLVYWLTTNV 245 M + FF Q K TV P Q+ +M PVIF V + FP G+++Y++ +N+ Sbjct: 471 MGVTMFFIQ-----KMSPTTVTDP---MQQKIMTFMPVIFTVFFLWFPSGLVLYYIVSNL 522 Query: 246 WTMGQQMYVI 255 T+ QQ + Sbjct: 523 VTIIQQQLIY 532
>cloacin#Cloacin signature. Length = 551 Score = 41.2 bits (96), Expect = 2e-05 Identities = 28/62 (45%), Positives = 33/62 (53%), Gaps = 9/62 (14%) Query: 844 NNNGGTNNGAGNGGAAGGPGTSP--------SPTSSLPGGGNGNGNGNGNGNGNGNGNGT 895 N NGG GGA+ G G S S + GGG+G+GNG GNGN G G+GT Sbjct: 19 NINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS-GGGSGT 77 Query: 896 GG 897 GG Sbjct: 78 GG 79
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 45.9 bits (109), Expect = 1e-07 Identities = 53/263 (20%), Positives = 88/263 (33%), Gaps = 28/263 (10%) Query: 26 LVPVCKGNGYGFGHERLADEAIRFGSDTLAVGTTYEAARI-KDWFSGDLLVLTPFRRGEE 84 + V K N YG G ER+ +D A+ EA + + + G +L+L F ++ Sbjct: 30 VWSVVKANAYGHGIERIWSAIG--ATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQD 87 Query: 85 PVPLPD-RVIRSVSSVDGVHALVGAR------VVIECMSSMKRHGVKEEELG---QLHAA 134 R+ V S + AL AR + ++ S M R G + + + Q A Sbjct: 88 LEIYDQHRLTTCVHSNWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRA 147 Query: 135 IEDVRLEGFALHLPLDRTDGSDAVEEVIGWMDRLRAARLPLHTMFVSHLRAEELGRLQQQ 194 + +V H + D + M R+ A L A L + Sbjct: 148 MANVGEMTLMSHFA--EAEHPDGISGA---MARIEQAAEGLECRRSLSNSAATLWHPEAH 202 Query: 195 FPQTRF---------RARIGTRLWLGDHEATEYRGAVLDVTRVVKGDRFGY-RQQKAASD 244 F R + G ++ V + G+R GY + A + Sbjct: 203 FDWVRPGIILYGASPSGQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDE 262 Query: 245 GWLVVVAGGTSHGVGLEAPKALH 267 + +VA G + G AP Sbjct: 263 QRIGIVAAGYADGYPRHAPTGTP 285
>cloacin#Cloacin signature. Length = 551 Score = 47.4 bits (112), Expect = 1e-08 Identities = 28/73 (38%), Positives = 34/73 (46%), Gaps = 1/73 (1%) Query: 122 GRGGQGGQGGYGGGQQGGGNWGGGPGGGGQQGGGGAPADDPWATSAPAGGQQGGGQQGGG 181 GRG G G GG G G GGG G G + ++PW + +G GGG G Sbjct: 6 GRGHNTGAHSTSGNINGGPT-GLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGN 64 Query: 182 GGWGGSSGGSGGG 194 GG G+SGG G Sbjct: 65 GGGNGNSGGGSGT 77 Score = 43.2 bits (101), Expect = 3e-07 Identities = 30/75 (40%), Positives = 35/75 (46%), Gaps = 5/75 (6%) Query: 125 GQGGQGGYGGGQQGGGNWGGGPGGGGQQGGGGAPADDPWATS-APAGGQQGGGQQGGGGG 183 G G+G G GN GGP G G GGGA W++ P GG G G GGG Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLG--VGGGASDGSGWSSENNPWGGGSGSGIHWGGGS 60 Query: 184 WGGSSG--GSGGGYS 196 G+ G G+ GG S Sbjct: 61 GHGNGGGNGNSGGGS 75 Score = 37.8 bits (87), Expect = 2e-05 Identities = 31/95 (32%), Positives = 32/95 (33%), Gaps = 23/95 (24%) Query: 112 NATAKVTKTTGRGGQGGQGGYGGGQQGGG------NWGGGPGGGGQQGGGGAPADDPWAT 165 N A T GG G G GG G G WGGG G G GGG Sbjct: 10 NTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGS--------- 60 Query: 166 SAPAGGQQGGGQQGGGGGWGGSSGGSGGGYSDEPP 200 G G GG G GG SG G + P Sbjct: 61 --------GHGNGGGNGNSGGGSGTGGNLSAVAAP 87 Score = 30.5 bits (68), Expect = 0.005 Identities = 19/55 (34%), Positives = 20/55 (36%) Query: 122 GRGGQGGQGGYGGGQQGGGNWGGGPGGGGQQGGGGAPADDPWATSAPAGGQQGGG 176 G G G GG G G G GGG GG + P A PA G G Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAG 101
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 29.8 bits (67), Expect = 0.046 Identities = 30/140 (21%), Positives = 57/140 (40%), Gaps = 20/140 (14%) Query: 372 HLRHRLPTQIPRLPARTNTDITLRSRKIPSMFWNSWTVRLAPPEGT-FARILASALAASL 430 R L + +P + + + + + +RL+ + R LA+ +AAS+ Sbjct: 27 QARQLLRER-GLVPLSVDENRGDQQKSGSTGLSLRRKIRLSTSDLALLTRQLATLVAASM 85 Query: 431 LIVDS-----RIDFDTATRRL-----GNVIEGHDLSRVLQRLDNHPGWAD-LVTALVRLA 479 + ++ + +L V+EGH L+ ++ PG + L A+V Sbjct: 86 PLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADAMKC---FPGSFERLYCAMVAAG 142 Query: 480 D---HLDAV-DVPIDYASRR 495 + HLDAV + DY +R Sbjct: 143 ETSGHLDAVLNRLADYTEQR 162
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.3 bits (60), Expect = 0.043 Identities = 13/71 (18%), Positives = 21/71 (29%), Gaps = 4/71 (5%) Query: 40 KGKVRRHIP----DYLLLTGQVPVVVDVKPLHRLSKAEVEFTFDWTRQTVESRGWKYDVW 95 KG D + G P ++ E +++ R+T R Y Sbjct: 789 KGYSVNTTFVTIADLVQALGADPGKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGYMRP 848 Query: 96 SEPPAVELENI 106 P V E+ Sbjct: 849 QVWPPVIAEDK 859
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.1 bits (127), Expect = 5e-11 Identities = 21/121 (17%), Positives = 47/121 (38%), Gaps = 5/121 (4%) Query: 6 ERRTALVDAAIEVLADEGARGLTFRAVDARAGVPVGTSSNYFANRDDLFMQAAARITVRM 65 E R ++D A+ + + +G + + AGV G +F ++ DLF + + Sbjct: 11 ETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNI 70 Query: 66 TPDPAKVEEAMRPTPS---RELVADLMRWLVQRMEDDRTGYLAMLELRLEATRRPALRNR 122 + + P RE++ ++ V E+ R + ++ + E A+ + Sbjct: 71 GELELEYQAKFPGDPLSVLREILIHVLESTVT--EERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 123 L 123 Sbjct: 129 A 129
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.2 bits (91), Expect = 1e-06 Identities = 14/59 (23%), Positives = 27/59 (45%) Query: 82 RSVIEGVRIHADERGSGLGTQLIEWAVDESRRQDCQLVQLTSDASRTDAHRFYERLGFT 140 ++IE + + D R G+GT L+ A++ ++ + L + A FY + F Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.041 Identities = 13/68 (19%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 131 PGRPRLPRRSRDGQPVTQLAYARRGEITPEMEYVAIRENVEPEVVREEIAAGRAVLPANV 190 PG+ + + + + E + + +R V P V+ E+ A +A P + Sbjct: 811 PGKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGYMRPQVWPPVIAEDKEADQAHAPGDQ 870 Query: 191 NHPE-IEP 197 + + +EP Sbjct: 871 DQQQPVEP 878
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 38.8 bits (90), Expect = 5e-05 Identities = 21/116 (18%), Positives = 27/116 (23%), Gaps = 3/116 (2%) Query: 411 VPVAPAVQPGAGPAAARAAVRGEAPAPAAPPAPVAAPPAPAQPVAPVAPQPPAEAPAPAG 470 VAPA P A P P P+ PP A V P P P Sbjct: 53 TMVAPADLE---PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Query: 471 GQRPGAWPTAAAPESGRRPGGWPTASAPGQSPVPQTAPATAPAQAAPAAPVPAVEP 526 P + P S + A+ + +P Sbjct: 110 KVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQP 165 Score = 34.6 bits (79), Expect = 0.001 Identities = 23/101 (22%), Positives = 30/101 (29%), Gaps = 8/101 (7%) Query: 431 RGEAPAPAAP-------PAPVAAPPAPAQPVAPVAPQPPAEAPAP-AGGQRPGAWPTAAA 482 E PAPA P PA + P A P PV P P P + P Sbjct: 40 VIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKP 99 Query: 483 PESGRRPGGWPTASAPGQSPVPQTAPATAPAQAAPAAPVPA 523 + ++ PA+ APA P + Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSS 140 Score = 31.5 bits (71), Expect = 0.009 Identities = 19/96 (19%), Positives = 32/96 (33%), Gaps = 3/96 (3%) Query: 621 APPQTGGGRLSAVAPAPQRPAPAPQQSYEPRPAPAPHQQPGAAPAAEPASQSYSAPEPPR 680 PP+ P P+ P AP +P+P P P +P + P R Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP---VKKVEQPKRDVKPVESR 124 Query: 681 SVAPEDDTPEADDPDLVDSALSGHDLIVRELGATVV 716 +P ++T A +A + + G + Sbjct: 125 PASPFENTAPARPTSSTATAATSKPVTSVASGPRAL 160 Score = 29.6 bits (66), Expect = 0.036 Identities = 17/107 (15%), Positives = 24/107 (22%), Gaps = 1/107 (0%) Query: 400 VPGPEALAHAPVPVAPAVQPGAGPAAARAAVRGEAPAPAAPPAPVAAPPAP-AQPVAPVA 458 + P+A+ P PV P P P P QP V Sbjct: 60 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVK 119 Query: 459 PQPPAEAPAPAGGQRPGAWPTAAAPESGRRPGGWPTASAPGQSPVPQ 505 P A + A + + + PQ Sbjct: 120 PVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQ 166
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 2e-14 Identities = 27/119 (22%), Positives = 48/119 (40%), Gaps = 2/119 (1%) Query: 1 MTTVRVLLADDEHLIRGALAALLALEDDLVVVAEAATGREALAMARAHRPDVAVLDLEMP 60 MT +L+ADD+ IR L L+ V + A A D+ V D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAA--TLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GADGVNVATSLRTELPGCRTMIVTSHGRPGHLKRALAAGVRAFVPKTVSARQLAGIIRT 119 + ++ ++ P +++++ +A G ++PK +L GII Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.026 Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 8/61 (13%) Query: 329 NVLRHG---DPRHCTIRFRASADAAVLL--VENDGAAAATGPGGNSGPGGSGLAGLRERL 383 N ++HG P+ I + + D + VEN G+ A ++G +GL +RERL Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTG---TGLQNVRERL 322 Query: 384 R 384 + Sbjct: 323 Q 323
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 29.9 bits (67), Expect = 0.040 Identities = 19/88 (21%), Positives = 29/88 (32%), Gaps = 11/88 (12%) Query: 577 LRRVLAGAGIHELPPGWGTPSLATSNATA----RTGLRAALPDLIALFDAPLLADAGLVE 632 +RVL G + W LR L D A +DA +V Sbjct: 9 FKRVLTGTLLLLSSYSWAQELDWLPIPYVYVAKGESLRDLLTDFGANYDAT------VVV 62 Query: 633 ARVVRKALRAASEGEPLPLDGLAHLAAT 660 + + + E + P D L H+A+ Sbjct: 63 SDKINDKVSGQFEHDN-PQDFLQHIASL 89
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 53.1 bits (127), Expect = 8e-10 Identities = 25/89 (28%), Positives = 29/89 (32%) Query: 433 PAAVAPAVPTPAPPKPTPTPTPTPKPDAPAPPAPPAPSPTPPPKSTPMPTPTPTPTPTPT 492 P AV P P+P P P P P +AP P P P P PK P P Sbjct: 58 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPV 117 Query: 493 PKPTPPPKPSTPPTPKPPAPAPTPPPSPP 521 P +T P + A P Sbjct: 118 ESRPASPFENTAPARLTSSTATAATSKPV 146 Score = 46.9 bits (111), Expect = 9e-08 Identities = 32/96 (33%), Positives = 37/96 (38%), Gaps = 10/96 (10%) Query: 434 AAVAPAVPTPAPPKPTP----TPTPTPKPDAPAPPAPPAPSPTPPPKSTPMPTPTPTPTP 489 +V + PAP +P TP P A PP P P P P+ P P P P Sbjct: 30 TSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEP-PKEAPVV 88 Query: 490 TPTPKPTPPPKPSTPP----TPKP-PAPAPTPPPSP 520 PKP P PKP PK P + P SP Sbjct: 89 IEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASP 124 Score = 40.4 bits (94), Expect = 1e-05 Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 5/75 (6%) Query: 456 PKPDAPAPPAPPAPSPTPPPKSTPMPTPTPTPTPTPTPKPTPPPKPSTPPTPKPPAPAPT 515 P P P P+ PP++ P P+P P P P P P Sbjct: 39 PAPAQPISVTMVTPADLEPPQAVQPPPEPVVE-----PEPEPEPIPEPPKEAPVVIEKPK 93 Query: 516 PPPSPPAPTVYRVSE 530 P P P V +V E Sbjct: 94 PKPKPKPKPVKKVQE 108 Score = 35.3 bits (81), Expect = 5e-04 Identities = 18/96 (18%), Positives = 21/96 (21%), Gaps = 3/96 (3%) Query: 422 QPKPEAGHAAKPAAVAPAVPTPAP---PKPTPTPTPTPKPDAPAPPAPPAPSPTPPPKST 478 P P PKP P P P P P P S Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASP 124 Query: 479 PMPTPTPTPTPTPTPKPTPPPKPSTPPTPKPPAPAP 514 T T + T P S P+ + Sbjct: 125 FENTAPARLTSSTATAATSKPVTSVASGPRALSRNQ 160
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.5 bits (141), Expect = 3e-12 Identities = 38/253 (15%), Positives = 69/253 (27%), Gaps = 61/253 (24%) Query: 60 PLRVDAQRNLEHVLRAAREVFGELGY-GAPMEDVARRAKVGVGTVYRRFPSKDVLVRRIA 118 + +AQ +H+L A +F + G + ++A+ A V G +Y F K L I Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 119 EEETSRLTDQARTALGQEEEPWSALSRFLRTSVASGAGRLLPPQVLRVGVDTDADADDSN 178 E S + + + P VLR + Sbjct: 64 ELSESNIGELELEYQAKFPG--------------------DPLSVLREILIH-------- 95 Query: 179 AAGESGSIAASVSDSGPGSARDETRVPQQRQGAGQADLRPADGRSTAETGIEDDGTGAGE 238 + T ++R+ + + + E Sbjct: 96 -------------------VLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLE 136 Query: 239 LLEIVGRLVDRARAAGELRRDVTVADV----------LLVIATAAPSLPDAAQQAAASSR 288 + + + + A L D+ L+ AP D ++A Sbjct: 137 SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEARD--- 193 Query: 289 LLDILLEGLRSRP 301 + ILLE P Sbjct: 194 YVAILLEMYLLCP 206
>BACSURFANTGN#Yersinia/Haemophilus virulence surface antigen signature. Length = 322 Score = 27.0 bits (59), Expect = 0.023 Identities = 8/34 (23%), Positives = 12/34 (35%), Gaps = 1/34 (2%) Query: 95 APLRAELADWARRARAAG-LEKDDVSALFTAVLD 127 + E R G E + + L A+LD Sbjct: 205 SERMIERHCLLRPVDVTGTTESEGLDQLLNAILD 238
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 5e-05 Identities = 22/100 (22%), Positives = 31/100 (31%), Gaps = 12/100 (12%) Query: 212 KGFFLAERDGELIGF-----HWTKVHADEHLGEVYVVGIRPDAQGGGLGKALTAIGLRHL 266 K FL + IG +W E + + D + G+G AL + Sbjct: 65 KAAFLYYLENNCIGRIKIRSNWNGYALIED------IAVAKDYRKKGVGTALLHKAIEWA 118 Query: 267 AAEGLPTAMLYVDADNKAALAVYERMGFATHEVDLM-YRT 305 ML N +A Y + F VD M Y Sbjct: 119 KENHFCGLMLETQDINISACHFYAKHHFIIGAVDTMLYSN 158
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.5 bits (248), Expect = 3e-26 Identities = 35/117 (29%), Positives = 58/117 (49%) Query: 10 RILIVDDEPAVREALQRSLAFEGYGTEVAVDGLDALARAESYAPDLIVLDIQMPRMDGLT 69 IL+ DD+ A+R L ++L+ GY + + + DL+V D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 70 AARRLRSAGTTTPILMLTARDTVGDRVTGLDAGADDYLVKPFELDELFARIRALLRR 126 R++ A P+L+++A++T + + GA DYL KPF+L EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 50.8 bits (121), Expect = 4e-09 Identities = 37/207 (17%), Positives = 61/207 (29%), Gaps = 61/207 (29%) Query: 146 IVEVNATSTAGTSTGSGVVITSDGEVVTNNHVISGASSIKVTLST------------GKT 193 + + + GT SGVV+ ++TN HV+ L G Sbjct: 90 VTYIQVEAPTGTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGF 148 Query: 194 YNAKVVGTDADKDLALIKLQG-------ASGLKTATLGDSSAVSVGDQVVAIGSPEGLTG 246 ++ + DLA++K +K AT+ +++ V + G P Sbjct: 149 TAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKP- 207 Query: 247 TVTSGIVSALDRDVTVAKDDSSGQGQGGWGGGGEQWPFEFGGRQFNGDTGNSTTTYKAIQ 306 V+ + +A+Q Sbjct: 208 ------VATMWESKGKITYLKG----------------------------------EAMQ 227 Query: 307 TDASLNPGNSGGALINMNGEVIGINSA 333 D S GNSG + N EVIGI+ Sbjct: 228 YDLSTTGGNSGSPVFNEKNEVIGIHWG 254
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 29.6 bits (66), Expect = 0.034 Identities = 15/68 (22%), Positives = 20/68 (29%) Query: 161 QPAIRPAQPAQPVQQPAPATAETGYLPPHPQPQAASGSYPLPPEAPVAPVAAEPVRAGAP 220 QP PA+ P ++T QP + S P V P Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199 Query: 221 ADAAPAAT 228 + PA T Sbjct: 1200 ENTTPATT 1207
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 35.8 bits (82), Expect = 5e-04 Identities = 31/173 (17%), Positives = 53/173 (30%), Gaps = 5/173 (2%) Query: 299 VQLRRAERAVSATNQDLTGLSGTRLGLAVV--GRLARKHGLNVSFRPSARGGTGALMMLP 356 A+ A S + + G K V A+ T +P Sbjct: 1064 QNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVP 1123 Query: 357 QELLTRTPVPVRASAPQPASESRPEPEPTHETAATTAAEAVPAFSDSPASETTGNLPRFG 416 + +P ++ QP +E E +PT + A ++ PA ET+ N+ + Sbjct: 1124 KVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPV 1183 Query: 417 ESGLPKRPRGRTLAAAEARTNTNGATETPRPRTADPKEQAARFSSFRQAVRAN 469 + E NT AT P + + R ++V N Sbjct: 1184 TESTTVN---TGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHN 1233
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 42.4 bits (99), Expect = 3e-06 Identities = 59/261 (22%), Positives = 97/261 (37%), Gaps = 18/261 (6%) Query: 84 KISNAVKAGNAPDLVSIEYPQLPEYVSQGALQDI--GQYFTDDIKKKLLPQAVELTTLGG 141 K G+ PD++ + + Y G L +I + F D KL P + G Sbjct: 72 KFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDKAFQD----KLYPFTWDAVRYNG 127 Query: 142 KNWAVPFDASPQSFYYRKDLFEKYGVEVPKTWDEFRKAAEKIKKADKKARIGTFFPDDPT 201 K A P S Y KDL PKTW+E A +K KA K+ + + Sbjct: 128 KLIAYPIAVEALSLIYNKDLLPN----PPKTWEEI-PALDKELKAKGKSALMFNLQEPYF 182 Query: 202 TFQAMAWQAGAQWYKPEG--DTWKVSTADAATNKVADYWQGLLDDDLIRANASFSPEWTN 259 T+ +A G + G D V +A + L+ + + A+ +S Sbjct: 183 TWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGLTFLVDLIKNKHMNADTDYSIA-EA 241 Query: 260 SLKNGGTVGYLGAAWGAGVLKGTLPEQSGKWAVAPMPSWDGKPASGMLGGSTFAVTKTSK 319 + G T + W + + V +P++ G+P+ +G + + S Sbjct: 242 AFNKGETAMTINGPWAWS----NIDTSKVNYGVTVLPTFKGQPSKPFVGVLSAGINAASP 297 Query: 320 KAEAAVEFATWMSTTEEGIKA 340 E A EF T+EG++A Sbjct: 298 NKELAKEFLENYLLTDEGLEA 318
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.5 bits (211), Expect = 6e-22 Identities = 59/186 (31%), Positives = 85/186 (45%), Gaps = 8/186 (4%) Query: 4 ALITGATAGIGAAFARRLAADGHNLVLVARNTERLR--EQATELHDRHGIEAEVLTADLS 61 A ITGA GIG A AR LA+ G ++ V N E+L + + RH AE AD+ Sbjct: 11 AFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARH---AEAFPADVR 67 Query: 62 EDKGIAAVEARLTDRHQSVDLLVNNAGFGNKGRYLDVPMADELNMLKVHCEAVLRLTSAA 121 + I + AR+ +D+LVN AG G + + V+ V + + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 122 AAGMRERGRGGVVNVASVAAFVPR---GTYGASKAWVVQFTQGAAKDLAGSGVRLMALCP 178 + M +R G +V V S A VPR Y +SKA V FT+ +LA +R + P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 179 GFVRTE 184 G T+ Sbjct: 188 GSTETD 193
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.7 bits (64), Expect = 0.043 Identities = 22/91 (24%), Positives = 40/91 (43%), Gaps = 13/91 (14%) Query: 320 LASGVGKWLSIV--VLTAAFLVAGLLTSSAVSR-----------RVREFGTLKALGWKSG 366 L +G+G + V V AFL AG++ +SA++ R+ T +A+ + Sbjct: 49 LGAGLGVMVGRVGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQL 108 Query: 367 RVTRQVVGEALVNGLLGGVLGISVGLAGAYV 397 R+ V+GE + G +G+ A + Sbjct: 109 RLGDIVLGEMAWAATKAALAGAGIGVVAAAL 139
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.4 bits (73), Expect = 0.002 Identities = 12/31 (38%), Positives = 19/31 (61%) Query: 34 LVIQGPTGGGKSTLLQMLGGLDRPTSGSVEL 64 +V++G G GKSTL+ L GLD + ++ Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDI 629
>cloacin#Cloacin signature. Length = 551 Score = 39.7 bits (92), Expect = 4e-05 Identities = 36/123 (29%), Positives = 48/123 (39%), Gaps = 7/123 (5%) Query: 220 GGDVVAGDGGRSGGTESGGTESGGSGSGSGGPDSGGAVASGGTDSGGADTAGGSDAAGGS 279 GGD G G +G + G +GG G GGA G S GGS + Sbjct: 3 GGD---GRGHNTGAHSTSGNINGGPTGLGVG---GGASDGSGWSSENNPWGGGSGSGIHW 56 Query: 280 HAAGGSDAAGGSNAAGGSNAAGGSDAAGGSNAAGGSNAAGGSDAAGGSGSGSSGGGDTAT 339 G GG+ +GG + GG+ +A + A G A + AGG S G +A Sbjct: 57 GGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPAL-STPGAGGLAVSISAGALSAA 115 Query: 340 QVD 342 D Sbjct: 116 IAD 118 Score = 37.0 bits (85), Expect = 3e-04 Identities = 27/101 (26%), Positives = 39/101 (38%), Gaps = 4/101 (3%) Query: 241 SGGSGSGSGGPDSGGAVASGGTDSGGADTAGGSDAAGGSHA----AGGSDAAGGSNAAGG 296 SGG G G + G +G G SD +G S GGS + G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 297 SNAAGGSDAAGGSNAAGGSNAAGGSDAAGGSGSGSSGGGDT 337 GG+ +GG + GG+ +A + A G + S+ G Sbjct: 62 HGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 32.0 bits (72), Expect = 0.012 Identities = 19/78 (24%), Positives = 27/78 (34%), Gaps = 1/78 (1%) Query: 277 GGSHAAGGSDAAGGSNAAGGSNAAGGSDAAGGSNAAGGSNAAGGSDAAGGSGSGSSGGGD 336 G+H+ G + GG G A N G + G GGSG G+ GG Sbjct: 11 TGAHSTSG-NINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 337 TATQVDDGGDDMDTSGEP 354 + G ++ P Sbjct: 70 NSGGGSGTGGNLSAVAAP 87
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 70.6 bits (173), Expect = 2e-16 Identities = 59/173 (34%), Positives = 82/173 (47%), Gaps = 9/173 (5%) Query: 93 LVPVVTALACAVLAAATGLRPELAVWLLLAPVGVLLATIDRRVHRLPDRLTLP--AAGAV 150 LV ++TAL +A LLL V V L ID LPD+LTLP G + Sbjct: 112 LVELLTALLSVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLL 171 Query: 151 VVLLGVAALLPEHGGSWLSALLGGAALGAFYFLL-FLINPNGMGFGDVKLALSLGAALGW 209 LLG L + + + A+ G L + Y+ L GMG+GD KL +LGA LGW Sbjct: 172 FNLLGGFVSLGD---AVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGW 228 Query: 210 YGWAVVFAGGFAGFLLGAVYGFGLMVLKRAGRKTGIPFGPFMITGALLGILLG 262 +V L+GA G GL++L+ + IPFGP++ + +L G Sbjct: 229 QALPIVL---LLSSLVGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWG 278
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 31.6 bits (71), Expect = 0.003 Identities = 31/132 (23%), Positives = 52/132 (39%), Gaps = 11/132 (8%) Query: 33 AVDDNNFEATAADTTLLADIPAGQQAQVQTASLTQQAD--AQASAADAAAKKSVE----- 85 A AT ++TT + Q+++ + + AQ AK +V+ Sbjct: 1023 APVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQT 1082 Query: 86 -EAARIQA-AKDAKSKKAAADDKLEQERKAKEAKEAEERASRSSVRSASSFAQQGSYTVA 143 E A+ + K+ ++ + +E+E KAK E E+ V S S Q+ S TV Sbjct: 1083 NEVAQSGSETKETQTTETKETATVEKEEKAKV--ETEKTQEVPKVTSQVSPKQEQSETVQ 1140 Query: 144 EIKAIARQIVPA 155 AR+ P Sbjct: 1141 PQAEPARENDPT 1152
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 154 bits (391), Expect = 4e-42 Identities = 89/463 (19%), Positives = 169/463 (36%), Gaps = 73/463 (15%) Query: 7 IRNVAIVAHVDHGKTTLVDAMLRQAGAFAAHAAENLDERMMDSNDLEREKGITILAKNTA 66 I N+ ++AHVD GKTTL +++L +GA + + D+ LER++GITI T+ Sbjct: 3 IINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITS 62 Query: 67 VKYHPKDGGDPITINIIDTPGHADFGGEVERGLSMVDAVVLLVDASEGPLPQTRFVLRKA 126 ++ +NIIDTPGH DF EV R LS++D +LL+ A +G QTR + Sbjct: 63 FQWEN------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 127 LAAKMPVILCINKTDR-------------------------------------PDSRIAE 149 +P I INK D+ +S + Sbjct: 117 RKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWD 176 Query: 150 VVDETYDLFLDLDADEDQIEFPIVYACARDGVASLTKPEDGTV-------PQDSENLEPF 202 V E D L+ +E + + ++ +++ ++ Sbjct: 177 TVIEGNDDLLEKYMSGKSLEALELEQEESIRFH------NCSLFPVYHGSAKNNIGIDNL 230 Query: 203 FSTILSHVPAPEYDDEAPLQAHVTNLDADNFLGRIALCRVEQGELRKGQTVTWIKRDGTM 262 I + + + ++ L V ++ R+A R+ G L +V +++ Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKE--- 287 Query: 263 SNVRITELLMTEALTRKPAEKAGPGDICAIAGIPDIMIGETLADPENPIALPLITVDEPA 322 ++ITE+ + +KA G+I + + + L D + I P Sbjct: 288 -KIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPL 345 Query: 323 ISMTIGTNTSPLVGKGGKGHKVTARQVKDRLDRELIGNVSLRVLDTERPDAWEVQGRGEL 382 + T+ + + D L + LR + G++ Sbjct: 346 LQTTVEPS-----------KPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKV 394 Query: 383 ALAILVEQMRRE-GFELTVGKPEVVTKQVDGKTHEPIERMTID 424 + + ++ + E+ + +P V+ + K E + + Sbjct: 395 QMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVP 437 Score = 40.2 bits (94), Expect = 2e-05 Identities = 16/89 (17%), Positives = 33/89 (37%), Gaps = 1/89 (1%) Query: 408 KQVDGKTHEPIERMTIDSPEEHLGAITQLMATRKGRMETMTNHGSGWVRMEWIVPSRGLI 467 K+ + EP I +P+E+L + V + +P+R + Sbjct: 529 KKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQ 587 Query: 468 GFRTEFLTQTRGTGIAHSIFEGHEPWFGE 496 +R++ T G + + +G+ GE Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVTTGE 616
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.040 Identities = 10/19 (52%), Positives = 15/19 (78%) Query: 55 TLAVLGESGSGKSVTAQAI 73 TL + GESG+GK + A+A+ Sbjct: 162 TLMITGESGTGKELVARAL 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.4 bits (66), Expect = 0.027 Identities = 26/95 (27%), Positives = 33/95 (34%), Gaps = 11/95 (11%) Query: 9 GSLDSTPNVTDVVEVEAADETAAVAAIEAPVERGEPILQVRNLVKHFPLSQGILFKRQIG 68 G+ D P D+ E+ A P + + LV Q I R + Sbjct: 97 GAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIY--RVLA 154 Query: 69 AVKAVDGVSFDLYQGETLGIVGESGCGKSTVARLL 103 + D TL I GESG GK VAR L Sbjct: 155 RLMQTDL---------TLMITGESGTGKELVARAL 180
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.5 bits (66), Expect = 0.024 Identities = 22/85 (25%), Positives = 28/85 (32%), Gaps = 8/85 (9%) Query: 245 DLYGNPRHPYTRALLSAVPEATADEAPARERIRLAGDVPSPVNPPSGCRFRTRCWKATDK 304 D+YG +L V A A A V S P G TR T+ Sbjct: 86 DVYGFAVINMNNGVLKVVRSKDAKTA--------AVPVASDAAPGIGDEVVTRVVPLTNV 137 Query: 305 CASEAPPLVRVEGSREGHLTACHYP 329 A + PL+R G + HY Sbjct: 138 AARDLAPLLRQLNDNAGVGSVVHYE 162
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 631 bits (1630), Expect = 0.0 Identities = 221/667 (33%), Positives = 345/667 (51%), Gaps = 32/667 (4%) Query: 1 MHTLNLGILAHVDAGKTSLTERLLHTAGVIDEIGSVDDGSTRTDSLALERQRGITIKSAV 60 M +N+G+LAHVDAGKT+LTE LL+ +G I E+GSVD G+TRTD+ LERQRGITI++ + Sbjct: 1 MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI 60 Query: 61 VSFAIDDITVNLIDTPGHPDFIAEVERVLNVLDGAVLVISAVEGVQAQTRVLMRTLQRLR 120 SF ++ VN+IDTPGH DF+AEV R L+VLDGA+L+ISA +GVQAQTR+L L+++ Sbjct: 61 TSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMG 120 Query: 121 IPTLIFVNKVDRGGAQDESLLRSISEKLTPAVLAMGSV-DGPGGRDARCTPYTAADARFT 179 IPT+ F+NK+D+ G ++ + I EKL+ ++ V P + T +T ++ Sbjct: 121 IPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYP---NMCVTNFTESEQ--- 174 Query: 180 DRLTELLADHDDALLAAYVENAAPLPYSRLREALSTQTRQALVHPVFFGSAITGAGVDAL 239 + + + +D LL Y+ + L + S + + PV+ GSA G+D L Sbjct: 175 ---WDTVIEGNDDLLEKYMSGKSLEA-LELEQEESIRFHNCSLFPVYHGSAKNNIGIDNL 230 Query: 240 ISGVRELLPVGEGDADGPVSGTVFKVERGPAGEKIAYVRIFSGTVRTRDRLPFGRGEGRD 299 I + + G VFK+E +++AY+R++SG + RD + R ++ Sbjct: 231 IEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSV---RISEKE 287 Query: 300 EGKVTAISVFDRGSDVREAAVGAGRIAKLRGLGGIRVGDAVGVSDTTAPGHW--FAPPTL 357 + K+T + G + +G I L+ +++ +G + P L Sbjct: 288 KIKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLL 346 Query: 358 ESVVVPCAPASRGELHFALAQLAEQDPLINLRQDDIRKEVSVSLYGEVQKEVIQATLADE 417 ++ V P P R L AL ++++ DPL+ D E+ +S G+VQ EV A L ++ Sbjct: 347 QTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTCALLQEK 406 Query: 418 FGIDVTFRETTTICLERPNGSGAAYEVGDQDPNPFLATIGLRIDPAPIGSGIEYRLEVEL 477 + +++ +E T I +ERP + PNPF A+IGL + P P+GSG++Y V L Sbjct: 407 YHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVSPLPLGSGMQYESSVSL 466 Query: 478 GSMPFSLMRAVEQTVGETLQQGIHGWQVTDCVVTMTHSGYWPRQSHSHAVFDKSMSSTAG 537 G + S AV + + +QG++GW VTDC + + Y+ S ST Sbjct: 467 GYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYY------------SPVSTPA 514 Query: 538 DFRNLTPLVLMSALKEAGTTVYEPMHRFRLELPADLLGPLLPVLAHLRAVPGTPAVQGAT 597 DFR L P+VL LK+AGT + EP F++ P + L A ++ Sbjct: 515 DFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNE 574 Query: 598 CVLEGEIPAARVHELQQQLPALTRGEGVLESGFDRYRAVVGTPPGRPRTDRDPLNRKEYL 657 +L GEIPA + E + L T G V + Y G P +P R P +R + + Sbjct: 575 VILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQP---RRPNSRIDKV 631 Query: 658 LHTVRRI 664 + +I Sbjct: 632 RYMFNKI 638
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 46.9 bits (111), Expect = 2e-08 Identities = 17/70 (24%), Positives = 31/70 (44%), Gaps = 3/70 (4%) Query: 255 VGRCVVDGRWAGFMAVE---VGPEYRRRGLATAVMTALARKALDEGASAAWLQVETDNEG 311 +GR + W G+ +E V +YR++G+ TA++ A + L+ + N Sbjct: 77 IGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINIS 136 Query: 312 ARALYERMGF 321 A Y + F Sbjct: 137 ACHFYAKHHF 146
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.1 bits (67), Expect = 0.024 Identities = 17/57 (29%), Positives = 25/57 (43%) Query: 25 SESGTTDDPDGPPRSPIAANAAEASSSGELASQKLTWKPCPAPSPAQGGGKTPSPLP 81 S+ TT D PR + +AEA ++ L P P+P + G P+P P Sbjct: 299 SQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEP 355
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.8 bits (77), Expect = 0.003 Identities = 20/106 (18%), Positives = 32/106 (30%), Gaps = 4/106 (3%) Query: 906 TEPPPTPAPTPHAPAPTPHVPAARTPQPAGEQRLTPEESRTLASWDRDLDALTGELRRAR 965 EP P P P P P P V P+P P+ + + RD+ + Sbjct: 74 VEPEPEPEPIPEPPKEAPVVIEKPKPKPKP----KPKPVKKVEQPKRDVKPVESRPASPF 129 Query: 966 ATVRDVLVPASLSATQLLRLADDPDGFAQELARPMPRPPQPAARRG 1011 +S + + + L+R P+ P A Sbjct: 130 ENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALR 175
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 41.3 bits (96), Expect = 2e-05 Identities = 26/73 (35%), Positives = 33/73 (45%), Gaps = 5/73 (6%) Query: 820 RHERTADESPEPYAAPEPYTAPAPAPAPAPAPAQAPAPAPAPAPAPAPAPVA----DALP 875 R + T + P A P P +PA PA PAP + P P P P P P A D P Sbjct: 312 RPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQP 371 Query: 876 GPRQPEQHSQPQQ 888 G R P+ + P + Sbjct: 372 GTR-PDSPAVPDR 383 Score = 35.5 bits (81), Expect = 0.001 Identities = 22/61 (36%), Positives = 25/61 (40%), Gaps = 3/61 (4%) Query: 829 PEPYAAPEPYTAPAPAPAPAPAPAQAPA--PAPAPAPAPAPAPVADALPGP-RQPEQHSQ 885 P P P AP P P +PA+ PA PAP P P P D P P+ Q Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370 Query: 886 P 886 P Sbjct: 371 P 371
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 40.8 bits (95), Expect = 2e-05 Identities = 36/206 (17%), Positives = 63/206 (30%), Gaps = 20/206 (9%) Query: 2 SDTTDLMGVTADKNVDSAAPAEGAATGTTARRRRSGTGLDGMVLAELQQ---VASGLGIK 58 S+TT+ + + + + E AT TTA+ R V A Q SG K Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETK 1093 Query: 59 GTARMRKGQLIEVIKEAQAGSSAAPKAAAPAADAETKPKRRATSKARTGDDSAAAAPAEK 118 T + V KE +A P ++ PK+ ++ T A A Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQE---QSETVQPQAEPAREND 1150 Query: 119 AA--AQQQIDIPGQPASDDQPTGERRR------------RRATAQAGSPETKAESKPAAE 164 ++ A +QP E + +PE + Sbjct: 1151 PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210 Query: 165 AKAQTQAEPKSDDRTDAKAEVAVDTA 190 +++ +PK+ R ++ Sbjct: 1211 VNSESSNKPKNRHRRSVRSVPHNVEP 1236 Score = 36.2 bits (83), Expect = 5e-04 Identities = 21/120 (17%), Positives = 39/120 (32%), Gaps = 5/120 (4%) Query: 70 EVIKEAQAGSSAAPKAAAPAAD----AETKPKRRATSKARTGDDSAAAAPAEKAAAQQQI 125 E I P A P+ AE + T + D + A + A + + Sbjct: 1015 EEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKS 1074 Query: 126 DIPGQP-ASDDQPTGERRRRRATAQAGSPETKAESKPAAEAKAQTQAEPKSDDRTDAKAE 184 ++ ++ +G + T + T + + A +TQ PK + K E Sbjct: 1075 NVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQE 1134
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.018 Identities = 18/72 (25%), Positives = 28/72 (38%), Gaps = 9/72 (12%) Query: 245 RIQLQQAFIKALMEQVKSVGVFSNPKTLFDLANTATKAITTDSDLGSVEQLTGFANGLK- 303 Q+A + AL Q+ NP +F+ N I D + E LT + ++ Sbjct: 155 ASMAQEAQLMALKAQI-------NPHFMFNALNNIRALILEDPT-KAREMLTSLSELMRY 206 Query: 304 GLASKNVHMVTL 315 L N V+L Sbjct: 207 SLRYSNARQVSL 218
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 29.6 bits (66), Expect = 0.023 Identities = 16/39 (41%), Positives = 19/39 (48%) Query: 275 QGGAQMHTVAAKAVAFGEAATPAFTAYAHRVVAHARVLA 313 Q A M + + GE A P FTA A V+A A V A Sbjct: 493 QNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAA 531
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 28.5 bits (63), Expect = 0.035 Identities = 21/72 (29%), Positives = 26/72 (36%), Gaps = 1/72 (1%) Query: 177 VMGGLR-SLTGIGGTSGEEHQFEFVGAGTVLLQSTEILMPEQPTGATPAQAGVPGGAGQP 235 V+G +L G T G + V LQ I + P G VPGGA Sbjct: 222 VLGASELTLDGGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGAVPGGAVPGGAVPG 281 Query: 236 GSAPRLPGQLGD 247 G P G + D Sbjct: 282 GFGPGGFGPVLD 293
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.0 bits (75), Expect = 0.002 Identities = 11/87 (12%), Positives = 18/87 (20%), Gaps = 1/87 (1%) Query: 6 PTPAGGPRDEAASSPHDPSAAPRAAHAGPAGPASASAPPTERADAIDPNPSPALRAAAPA 65 P A P E P +P P A P + + Sbjct: 62 PPQAVQPPPEPVVEP-EPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKP 120 Query: 66 ADATPDGPAPGMSRGYRAVFAVREFRA 92 ++ P P + + Sbjct: 121 VESRPASPFENTAPARPTSSTATAATS 147
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 485 bits (1251), Expect = e-174 Identities = 185/401 (46%), Positives = 255/401 (63%), Gaps = 9/401 (2%) Query: 16 RVLVLNSGSSSVKYQLLDMSDRSRLAVGLVERIGEETSRLVHTPLAGSGAESRERIGPIA 75 ++LV+N GSSS+KYQL++ D + LA GL ERIG S L H + E + + Sbjct: 2 KILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLTHN----ANGEKIKIKKDMK 57 Query: 76 DHEAALKAAAGELAADGLGLDSP--ALAAIGHRVVHGGLRFTEPVVIDDEVLKEIERLVP 133 DH+ A+K L G+ + A+GHRVVHGG FT V+I D+VLK I + Sbjct: 58 DHKDAIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIE 117 Query: 134 VAPLHNPANIVGIRTAQALRPDLPQVAVFDTAFHTTMPEYAARYAIDVETADAHRIRRYG 193 +APLHNPANI GI+ + PD+P VAVFDTAFH TMP+YA Y I E ++IR+YG Sbjct: 118 LAPLHNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYG 177 Query: 194 FHGTSHAYVSRKAAELLGRTPEEVNVIVLHLGNGASASAVAGGRCVETSMGLTPLEGLVM 253 FHGTSH YVS++AAE+L + E + +I HLGNG+S +AV G+ ++TSMG TPLEGL M Sbjct: 178 FHGTSHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAM 237 Query: 254 GTRSGDIDPAVTFHLKRVAGMSTDEIDVLLNKKSGLVGLCG-DNDMREIRRR-IDEGDER 311 GTRSG IDP++ +L +S +E+ +LNKKSG+ G+ G +D R++ GD+R Sbjct: 238 GTRSGSIDPSIISYLMEKENISAEEVVNILNKKSGVYGISGISSDFRDLEDAAFKNGDKR 297 Query: 312 AALAFDIYVHRLKKYIGAYSAVLGRVDAVVFTAGVGENSAPVREAAIAGLEEFGLAVDAD 371 A LA +++ +R+KK IG+Y+A +G VD +VFTAG+GEN +RE + GLE G +D + Sbjct: 298 AQLALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKE 357 Query: 372 LNAARSGAPRLISPDHARVAVAVVPTDEELEIAVQTFALIG 412 N G +IS ++V V VVPT+EE IA T ++ Sbjct: 358 KN-KVRGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVE 397
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.7 bits (74), Expect = 0.002 Identities = 22/46 (47%), Positives = 27/46 (58%), Gaps = 2/46 (4%) Query: 94 VHGQRAATARA-VEDEGGTEEEAGEVPGAPAGE-SPEPPAGPPPAR 137 +HG + + A A V E G E AG V GAPAG +P+PP PP R Sbjct: 81 IHGLKVSKAAAQVAREEGLESVAGIVMGAPAGAPAPKPPRPEPPPR 126
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 2e-15 Identities = 33/179 (18%), Positives = 65/179 (36%), Gaps = 16/179 (8%) Query: 4 VLVVEDDPVAADAHQLYVGRVPGFTVAAVAHSRAEAVRALDRTPVDLLLLDLYLPDGHGL 63 +LV +DD + R G+ V + + A R + DL++ D+ +PD + Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVRITS-NAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 64 QLLRSLRAAGHSADVIAVTSARDLTVVREGVSLGVVQYVLKPFTFATLRDRLVRYAEFRA 123 LL ++ A V+ +++ + G Y+ KPF L + R A Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR-ALAEP 122 Query: 124 AAGEASGQDEVDRALGVLRAPQPTRLPKGLSGPTLDAVTRVLRAAPDGVT---SGATGV 179 + +D+ + ++ G S + + R +T +G +G Sbjct: 123 KRRPSKLEDDSQDGMPLV----------GRSAAMQEIYRVLARLMQTDLTLMITGESGT 171
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 32.6 bits (74), Expect = 4e-04 Identities = 11/54 (20%), Positives = 20/54 (37%), Gaps = 1/54 (1%) Query: 93 ISLRPAFRGRGLGVDVLQALCEYGFTVRGLQRLQIETLTDNAPMIAAATRVGFT 146 I++ +R +G+G +L E+ L +ET N + F Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKE-NHFCGLMLETQDINISACHFYAKHHFI 147
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 33.4 bits (76), Expect = 0.003 Identities = 17/85 (20%), Positives = 24/85 (28%), Gaps = 7/85 (8%) Query: 11 PAATEVPQVPLLTPAETAPPAAPAKAAT------PPSSEPAAPAKRKKPAGERAAKTGDG 64 PA E PQ P P + P E P + KP + + Sbjct: 57 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116 Query: 65 -AAPPRPRRGTGSQGVRQARPLGNG 88 P R + + ARP + Sbjct: 117 DVKPVESRPASPFENTAPARPTSST 141
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 258 bits (659), Expect = 6e-80 Identities = 176/573 (30%), Positives = 251/573 (43%), Gaps = 76/573 (13%) Query: 19 AALLAVGVQTGTATATPGSATAAATAGANR-----GALAKQLTPSQRAELIREADASKAA 73 A L A+G+ G G++ + N ++ L EL+ + Sbjct: 5 AMLGAIGLAFGLMAWPFGASAKGKSMVWNEQWKTPSFVSGSLLGRCSQELVYRY-LDQEK 63 Query: 74 TAKELGLGSQEKLVVRDVIQDNDGTTHTRYERTFAGLPVLGGDLVVQETKAGATE-SVTK 132 +LG ++E+L + D G T R+E+ A +G LV + S T Sbjct: 64 NTFQLGGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVNDGELSSLSGTL 123 Query: 133 ASKVSSGQLKAVDTTADVAPAVAQKQALGLAKADGSKKTAADRAP-------RKVVWMAQ 185 + LK A++ +QA +AK D + + +R R V++ + Sbjct: 124 IPNLDKRTLK-------TEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDE 176 Query: 186 GKPQLAYETVVGGLQEDGTPNELHVITDASTGAKLYEWQGVEN---------------GT 230 P+LAYE V L P + DA+ G L +W ++ G Sbjct: 177 ETPRLAYEVNVRFLTPV--PGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGV 234 Query: 231 GNTQYNGQVTLGTAPS-----YTLTDTGRGNH-KTYNLNHGSSGTGTLFTNSTDVWGNGN 284 G Q + T S Y L D RG+ TY+ + + G+L+ + + + Sbjct: 235 GRGVLGDQKYINTTYSSYYGYYYLQDNTRGSGIFTYDGRNRTVLPGSLWADGDNQFFASY 294 Query: 285 PSNAETAAADAHYGAAETWDYYKNVHGRTGIRGDGVGAYSRVHYGNAYVNAFWQDSCFCM 344 + AA DAHY A +DYYKNVHGR G S VHYG Y NAFW S M Sbjct: 295 ----DAAAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQ--M 348 Query: 345 TYGDGEG-NLKPLT-SLDVAAHEMSHGVTAATAKLVYSGESGGLNEATSDIFAAGVEFYS 402 YGDG+G P + +DV HE++H VT TA LVY ESG +NEA SDIF VEFY+ Sbjct: 349 VYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYA 408 Query: 403 NTAEDPGDYLVGEKI---DINGDGTPLRYMDKPSKDGASKDA--WYSGIG-NIDVHYSSG 456 N D+ +GE I + GD LR M P+K G Y+G N VH +SG Sbjct: 409 NRNP---DWEIGEDIYTPGVAGDA--LRSMSDPAKYGDPDHYSKRYTGTQDNGGVHTNSG 463 Query: 457 PANHFFYLLSEGSGAKVINGVSYDSPTSDGLPVTGIGRAKAEQIWFKALATKFTSTTNYA 516 N YLLS+G G+ VTGIGR K +I+++AL T T+N++ Sbjct: 464 IINKAAYLLSQGG-------------VHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFS 510 Query: 517 AARTGTLAVAGELYGTTSAEYKAVGDAWAAINV 549 R + A +LYG+TS E +V A+ A+ V Sbjct: 511 QLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 66.5 bits (162), Expect = 4e-15 Identities = 47/213 (22%), Positives = 77/213 (36%), Gaps = 22/213 (10%) Query: 86 LSRGRIVRAAIELADAEGLPAVSMRRVATTLSTSTMALYRHVPGKAELVRLMSDEVFGER 145 L+R ++ AA+EL + G+ ++ R++A L LY HV K L+ ++ E+ Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 146 PLGTVP---RDWRSGLEVAARWLRSVYGRHPWMAQATASFTRPTASPHAMRYTEWVLHAL 202 ++P W+S L A R R+ A+ TRP E L + Sbjct: 64 HDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLG-TRPD--EKQYDTVETQLRFM 120 Query: 203 RGTGLSPHTMLHIHLTLFAHVQGLAMGADSEAQARQDTGLSDVEWRVRNEPQFNAISASG 262 G S L+ ++ +H +GA E Q + + R A Sbjct: 121 TENGFSLRDGLYA-ISAVSH---FTLGAVLEQQEHT----AALTDRP-------AAPDEN 165 Query: 263 DYPFLNSLFEHDEFELDLDSLFEFGLQRTLDGI 295 P L D + F GL+ + G Sbjct: 166 LPPLLREAL-QIMDSDDGEQAFLHGLESLIRGF 197
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 170 bits (432), Expect = 1e-49 Identities = 85/394 (21%), Positives = 158/394 (40%), Gaps = 14/394 (3%) Query: 5 LFVSMDVSILFYALPAIGADLEPGSTQQLWILDIYGFVLAGLLITMGALGDRIGRRTVLI 64 F ++ +L +LP I D W+ + + G L D++G + +L+ Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 65 TGTVLFAAASVAAAYAQSPGA-LIAARALLGVGGACLMPSTLALVRNLFHDPRQRARAVA 123 G ++ SV S + LI AR + G G A P+ + +V + R +A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA-AFPALVMVVVARYIPKENRGKAFG 142 Query: 124 LWTTVMATGISVGPVVSGALLEHFWWGAVFLVNLPAMALLLVLAPLLLPESRTPGEGRFD 183 L +++A G VGP + G + + W + L+ + + + L LL E R G FD Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGH--FD 200 Query: 184 ILSAVLSLAALLPLIHGIKEVAKHGYQPLPALGITAGLALGFVFLRRQARLVHPMVDLAL 243 I +L ++ + + + + L +F++ ++ P VD L Sbjct: 201 IKGIILMSVGIVFFMLFTTSYSI-SFLIVSVLSF-------LIFVKHIRKVTDPFVDPGL 252 Query: 244 LRRRAFGGPVLVNLLAMAATVGFAAFFSQYVQSVLGKSPFEAAMWSLVP-SLGVVVCAPA 302 + F VL + GF + ++ V S E + P ++ V++ Sbjct: 253 GKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYI 312 Query: 303 GGALARRFDRGYVMGGGFLVSAAGFLSLTRIGTQSPLWMTLAGSAVYAGGLVSAMTLANE 362 GG L R YV+ G + FL+ + + + +MT+ V GGL T+ + Sbjct: 313 GGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVL-GGLSFTKTVIST 371 Query: 363 LALGAAPPERAGSAAAVLESGQELGGALGMALLG 396 + + + AG+ ++L L G+A++G Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 33.3 bits (76), Expect = 0.004 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 14/113 (12%) Query: 134 LDIYRLLITGGLVYGFGRLGNW--PAAFERCVAARGAAARAGGAAIGALLVWILVWNGTV 191 L I RLL+ G ++ FG + + + F + AR AG AA AL++ ++ Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQG-AGAAAFPALVMVVVARYIPK 134 Query: 192 PGMGLAFGLVPGSWLGPDQPMSPVV----------SYGLYVLLTLVIVWPFAR 234 G AFGL+ GS + + + P + SY L + + +I PF Sbjct: 135 ENRGKAFGLI-GSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLM 186
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.003 Identities = 16/89 (17%), Positives = 31/89 (34%) Query: 407 QALSVARRRGRALVEHEELATGSVLPLLADDAVRAFADGMLRALHEHDAKGRGDLVASLR 466 ++ +A L+ + +F D + + + L Sbjct: 384 RSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILA 443 Query: 467 AWLSHHGQWDAAAADLGVHRHTLRYRMRR 495 A + G AA LG++R+TLR ++R Sbjct: 444 ALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 69.1 bits (169), Expect = 5e-14 Identities = 43/143 (30%), Positives = 62/143 (43%), Gaps = 22/143 (15%) Query: 537 VMGHVDHGKTRLLDAIRKTNVVAGEAG------------------GITQHIGAYQVSSEV 578 V+ HVD GKT L +++ + E G GIT G + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI----TSF 63 Query: 579 NGEDRRITFIDTPGHEAFTAMRARGAKSTDIAILVVAANDGVMPQTIEALNHAKAADVPI 638 E+ ++ IDTPGH F A R D AIL+++A DGV QT + + +P Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT 123 Query: 639 VVAVNKIDVEGADPTKVRGQLTE 661 + +NKID G D + V + E Sbjct: 124 IFFINKIDQNGIDLSTVYQDIKE 146
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 29.5 bits (66), Expect = 0.024 Identities = 18/104 (17%), Positives = 45/104 (43%), Gaps = 7/104 (6%) Query: 173 DPGLIIADEPTTALDVMIQAQILRLIEQLVSEQDL--GLIMISHDLAVLSDTCDRLAVMY 230 +I A T AL V ++ +E+++++ D+ +++ A++++ D + Sbjct: 308 KNIIIKAHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVE---AIIAEVQDADGLNL 364 Query: 231 AGRVVEEGPASEVYENAHHPYGKALSGA--FPRIGDPASRFAPR 272 + + + N+ P A++GA + + G +S A Sbjct: 365 GIQWANKNAGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASA 408
>PERTACTIN#Pertactin signature. Length = 922 Score = 36.2 bits (83), Expect = 7e-04 Identities = 23/68 (33%), Positives = 26/68 (38%), Gaps = 7/68 (10%) Query: 338 PQGGYGFPQQPAPPAPQAPEQGGYGFPQPPQAPQPPHVPEQGGYGFPQPPQAPQPPQAPQ 397 G + APPAP+ Q G P P P P PQPPQ PQ Sbjct: 556 GNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQP-------PQPPQPPQRQPEAP 608 Query: 398 TPQWPAQQ 405 PQ PA + Sbjct: 609 APQPPAGR 616 Score = 32.8 bits (74), Expect = 0.007 Identities = 19/62 (30%), Positives = 20/62 (32%) Query: 259 PPPNTPQDTPAPAMPTPWTPAPPQSGLPPLPPAFHPATPQPSAPRSAPQWPAQTPADQTP 318 N P PAP P P P PQP P PQ + PA Q P Sbjct: 554 ANGNGQWSLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613 Query: 319 DG 320 G Sbjct: 614 AG 615 Score = 31.6 bits (71), Expect = 0.015 Identities = 29/84 (34%), Positives = 35/84 (41%), Gaps = 7/84 (8%) Query: 780 AQQQQGLWTSNGSNPPPQYAP-PMPGQQQYSPQQPHQPYPPQQQPYGGQQPPQSYPPQPG 838 A G W+ G+ PP P P PG Q QP QP P Q P QPPQ QP Sbjct: 553 AANGNGQWSLVGAKAPPAPKPAPQPGPQ--PGPQPPQPPQPPQPP----QPPQPPQRQPE 606 Query: 839 PGVQQNGWQQSLPSQAQSAASPAG 862 Q + L + A +A + G Sbjct: 607 APAPQPPAGRELSAAANAAVNTGG 630 Score = 31.6 bits (71), Expect = 0.015 Identities = 23/53 (43%), Positives = 24/53 (45%) Query: 305 APQWPAQTPADQTPDGYGFPHAGAPQPPQAPQPPQGGYGFPQQPAPPAPQAPE 357 A PA PA Q G PQPPQ PQPPQ P+ PAP P E Sbjct: 565 AKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRE 617 Score = 30.5 bits (68), Expect = 0.043 Identities = 19/49 (38%), Positives = 19/49 (38%) Query: 254 APQDVPPPNTPQDTPAPAMPTPWTPAPPQSGLPPLPPAFHPATPQPSAP 302 A P PQ P P P P PPQ PP PP P P P P Sbjct: 565 AKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPP 613
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 30.5 bits (69), Expect = 0.013 Identities = 22/79 (27%), Positives = 33/79 (41%), Gaps = 14/79 (17%) Query: 29 RGSSRGARGPASARLNGRPGQLGSFRLQQLVLLETAVALLLAAWVIEP-LLLAPAVVVAA 87 RG RG + P SAR LV L TA+ + A + P A+++ Sbjct: 96 RGRCRGCQAPISARY-------------PLVELLTALLSVAVAMTLAPGWGTLAALLLTW 142 Query: 88 LLVLLAVVRRHRRSLPEWL 106 +LV L + + LP+ L Sbjct: 143 VLVALTFIDLDKMLLPDQL 161
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 227 bits (580), Expect = 9e-74 Identities = 88/296 (29%), Positives = 146/296 (49%), Gaps = 12/296 (4%) Query: 46 TFPMKQQYEGRPWSLQRVLLDELWQDTKGKGVRVAVIDTGVDNVNPQLKTAVDTSAGADY 105 +QQ P ++ + +W T+G+GV+VAV+DTG D +P LK + Sbjct: 12 VIKQEQQVNEIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADHPDLKARIIGGRNFTD 71 Query: 106 LKGGKSDGTVDEVGHGTKVAGIIAARPRKGTGFVGLAPEATIIPIRQNDEKNSGKDTTMA 165 G + D GHGT VAG IAA G VG+APEA ++ I+ +++ SG+ + Sbjct: 72 DDEGDPEIFKDYNGHGTHVAGTIAATE-NENGVVGVAPEADLLIIKVLNKQGSGQYDWII 130 Query: 166 TAIDHAIAKGADVINISQDTTKALTEASALGRAVARALAKDIVVVASAGNDGMDGKLKRT 225 I +AI + D+I++S + + L AV +A+A I+V+ +AGN+G Sbjct: 131 QGIYYAIEQKVDIISMSLGGPE---DVPELHEAVKKAVASQILVMCAAGNEGDGDDRTDE 187 Query: 226 --YPAAFDGVLAVASSDRNNERAPFSQAGEFVGVAAPGVDIVSTVPGNGQCTDNGTSFSA 283 YP ++ V++V + + + + FS + V + APG DI+STVPG T +GTS + Sbjct: 188 LGYPGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVPGGKYATFSGTSMAT 247 Query: 284 PYVAGVAALMRAKYP-----KWTAAQIVARIEQTAERSVTGHDDFVGWGVVDPVRA 334 P+VAG AL++ T ++ A++ + + G G++ Sbjct: 248 PHVAGALALIKQLANASFERDLTEPELYAQLIKRTI-PLGNSPKMEGNGLLYLTAV 302
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 6e-21 Identities = 37/172 (21%), Positives = 63/172 (36%), Gaps = 15/172 (8%) Query: 4 VLVVDDDIRVAKVNAAYVSRVPGFRVAAQAHSAAEALATIEEQRVDLVLLDHYMPERNGL 63 +LV DDD + V +SR G+ V +AA I DLV+ D MP+ N Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 64 TMVRELRRLGHHTDVIMVTAARDVATVHEAMRHGALQYLVKPFTYAGLRTKLEAYATLRH 123 ++ +++ V++++A T +A GA YL KPF L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF---DLTELIGIIGRALA 120 Query: 124 TLEGGGEAEQGEVDRLFGALWAAGEPDLPKGHSPTTAELVKQALRSAEGPLS 175 + + + + G S E+ + R + L+ Sbjct: 121 EPKRRPSKLEDDSQDGMPLV----------GRSAAMQEIYRVLARLMQTDLT 162
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 37.5 bits (86), Expect = 4e-05 Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 1/74 (1%) Query: 77 HQADVAAKAKAEAQRKAEAKKRAEAKKKAEAKAKAEAKRAAEARAEKARAARSAERTRLG 136 + + +A + Q + A+A +A A KA + AAEA+ + AR R Sbjct: 188 YNVKLFTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAA 247 Query: 137 -SFQLPVAGSYVTT 149 ++ +P GS V T Sbjct: 248 NTYAMPANGSVVAT 261
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 30.3 bits (68), Expect = 0.029 Identities = 12/68 (17%), Positives = 21/68 (30%) Query: 628 PRPSAQSSAAATPPRAGAATTTGPGPATPSAPATGSGKATTADAGTDGGPGVRAGRIPAY 687 + Q P + A+ +T + + GP + P Y Sbjct: 108 VKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQY 167 Query: 688 PAAERAVR 695 PA +A+R Sbjct: 168 PARAQALR 175
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.1 bits (70), Expect = 0.007 Identities = 13/42 (30%), Positives = 21/42 (50%) Query: 146 ADKLIAGASKATATVGAGIGAAAMMPVPPAMLAELAAEITGV 187 D + S A+V +GI AAA + A ++ L +TG+ Sbjct: 364 IDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGI 405
>ARGDEIMINASE#Bacterial arginine deiminase signature. Length = 409 Score = 411 bits (1058), Expect = e-144 Identities = 150/414 (36%), Positives = 218/414 (52%), Gaps = 16/414 (3%) Query: 2 GFHVDSEAGRLRRVILHRPDLELKRLTPSNKDALLFDDVLWVRRARQEHDGFADVLRDRG 61 ++ SE GRL++V+LHRP EL+ LTP LFDD+ ++ ARQEH+ FA +L++ Sbjct: 7 PINIFSEIGRLKKVLLHRPGEELENLTPFIMKNFLFDDIPYLEVARQEHEVFASILKNNL 66 Query: 62 VEVHLFGDLLRESLEIPVA-RRLVLDRVFEEKEYG-PLATEHLRAAFEELPSAELAEALV 119 VE+ DL+ E L VA + + E E L+ F L + ++ Sbjct: 67 VEIEYIEDLISEVLVSSVALENKFISQFILEAEIKTDFTINLLKDYFSSLTIDNMISKMI 126 Query: 120 GGMTKREFLERHSEPTSVRFHVMDLDDFLLGPLPNHLFTRDTSAWIYDGVSINAMRWPAR 179 G+ E S + V + F++ P+PN LFTRD A I +GV+IN M R Sbjct: 127 SGVVTEELKNYTSSLDDL---VNGANLFIIDPMPNVLFTRDPFASIGNGVTINKMFTKVR 183 Query: 180 QRETVHFEAIYRHHPLFTGPDAGVFHHWSEGQDDYPSTIEGGDVLVIGHGAVLIGMSERT 239 QRET+ E I+++HP++ W +++EGGD LV+ G ++IG+SERT Sbjct: 184 QRETIFAEYIFKYHPVY----KENVPIWLN--RWEEASLEGGDELVLNKGLLVIGISERT 237 Query: 240 TPQAVEMLARGLF-DAGSAHTIVALDMPKRRAFMHLDTVMTMIDGDTFTKYAGL-GMLRS 297 ++VE LA LF + S TI+A +PK R++MHLDTV T ID FT + Sbjct: 238 EAKSVEKLAISLFKNKTSFDTILAFQIPKNRSYMHLDTVFTQIDYSVFTSFTSDDMYFSI 297 Query: 298 YTIEPG-EGPRDLKVTDHPPKHMHDAIAHALGLDSIRVLTATQDVHAAQREQWDDGCNVL 356 Y + + + + D ++ LG + A D+ REQW+DG NVL Sbjct: 298 YVLTYNPSSSKIHIKKEKAR--IKDVLSFYLGRKIDIIKCAGGDLIHGAREQWNDGANVL 355 Query: 357 AVEPGVVVAYERNATTNTYLRKEGIEVIEIRGSELGRGRGGPRCMSCPVVRDPV 410 A+ PG ++AY RN TN + GI+V I SEL RGRGGPRCMS P++R+ + Sbjct: 356 AIAPGEIIAYSRNHVTNKLFEENGIKVHRIPSSELSRGRGGPRCMSMPLIREDI 409
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.3 bits (89), Expect = 1e-05 Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 5/103 (4%) Query: 18 KPTAMVVVADPRVRSTVTRHLWALGVRDVIEASSIAEARPRVGN-PRDICVADVHLPDGS 76 T +V D +R+ + + L G DV S+ A + D+ V DV +PD + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGY-DVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 77 GLTLLSETRAAGWPNG--LALSAADDIGAVRNALAGGVKGYVV 117 LL + A P+ L +SA + A G Y+ Sbjct: 62 AFDLLPRIKKA-RPDLPVLVMSAQNTFMTAIKASEKGAYDYLP 103
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.3 bits (63), Expect = 0.014 Identities = 12/54 (22%), Positives = 19/54 (35%), Gaps = 1/54 (1%) Query: 52 TVYAAICGGSEFLGGMGLALGLFTPLAAAALIGVMI-NAMVTVTAAHGLWETQG 104 V I G ++ + IG+ NA++ V A L E +G Sbjct: 903 VVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEG 956
>cloacin#Cloacin signature. Length = 551 Score = 37.0 bits (85), Expect = 9e-05 Identities = 26/77 (33%), Positives = 33/77 (42%), Gaps = 9/77 (11%) Query: 278 GAGPGNGSCGSTNNGGSGGGGGGCSSGASCGSGSSCS---------SGSGCGGSSGSSCS 328 G G G+ ++ N G G G GAS GSG S SG GG SG Sbjct: 6 GRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNG 65 Query: 329 SSSGSSCGGGSSCGSSS 345 +G+S GG + G+ S Sbjct: 66 GGNGNSGGGSGTGGNLS 82 Score = 34.3 bits (78), Expect = 7e-04 Identities = 18/47 (38%), Positives = 21/47 (44%) Query: 275 WCAGAGPGNGSCGSTNNGGSGGGGGGCSSGASCGSGSSCSSGSGCGG 321 W G+G GNG + GGSG GG + A G S G GG Sbjct: 56 WGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGG 102 Score = 33.5 bits (76), Expect = 0.001 Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 6/61 (9%) Query: 280 GPGNGSCGSTNNGGSGGG------GGGCSSGASCGSGSSCSSGSGCGGSSGSSCSSSSGS 333 GP G + GSG GGG SG G GS +G G G S G S + + S Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLS 82 Query: 334 S 334 + Sbjct: 83 A 83 Score = 32.8 bits (74), Expect = 0.002 Identities = 21/83 (25%), Positives = 34/83 (40%), Gaps = 7/83 (8%) Query: 258 GSRSSSDSSGMFVAPVMWCAGAGPGNGSCGSTNNGGSGGGGGGCSSGASCGSGSSCSSGS 317 +SD SG W G+G G G + +G GG G + G+ S+ ++ Sbjct: 29 VGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPV 88 Query: 318 GCG-------GSSGSSCSSSSGS 333 G G+ G + S S+G+ Sbjct: 89 AFGFPALSTPGAGGLAVSISAGA 111 Score = 32.8 bits (74), Expect = 0.002 Identities = 25/79 (31%), Positives = 31/79 (39%), Gaps = 11/79 (13%) Query: 278 GAGPGNGSCGSTNNGGSGGGG--GGCSSGASC---------GSGSSCSSGSGCGGSSGSS 326 G G S NGG G G GG S G+ GSGS G G G +G Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGG 67 Query: 327 CSSSSGSSCGGGSSCGSSS 345 +S G S GG+ ++ Sbjct: 68 NGNSGGGSGTGGNLSAVAA 86 Score = 31.6 bits (71), Expect = 0.005 Identities = 20/66 (30%), Positives = 26/66 (39%), Gaps = 5/66 (7%) Query: 278 GAGPGNGSC-----GSTNNGGSGGGGGGCSSGASCGSGSSCSSGSGCGGSSGSSCSSSSG 332 G G G G+ S NN GG G G G G G+ +G+ GGS S+ Sbjct: 26 GLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85 Query: 333 SSCGGG 338 + G Sbjct: 86 APVAFG 91 Score = 28.9 bits (64), Expect = 0.035 Identities = 20/52 (38%), Positives = 25/52 (48%), Gaps = 3/52 (5%) Query: 294 SGGGGGGCSSGASCGSGSSCSSGSGCGGSSGSSCSSSSGSS---CGGGSSCG 342 SGG G G ++GA SG+ +G G G+S S S GGGS G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSG 53
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.025 Identities = 12/36 (33%), Positives = 19/36 (52%) Query: 17 IEGANGTGKSTLLRLLAGIDAPTEGRITDRRPRTAY 52 +EG G GKSTL+ L G+D ++ + +Y Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSY 636
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.9 bits (67), Expect = 0.048 Identities = 37/162 (22%), Positives = 56/162 (34%), Gaps = 24/162 (14%) Query: 79 RTVALGGPGADRFHAHAVHLPAGTGLPGDVPAITAWRSPNWASTTPD--GGTPGRMASLP 136 RTV L P + H H V + T L + + A D R+ S P Sbjct: 131 RTVELPQPDPETGHTHRVQIALDTALSDQDQS-----AHYVAPERADSEKPREFRLVSDP 185 Query: 137 ASAAFGPEALNDFAVSR--------SPWLAAVFADLRRASEESSSTRVVLVERQSADVAR 188 + ++ + L S WL +F D +RA S + AR Sbjct: 186 GAMSWFLQRLEADEDGNAVDLQLWVSDWLKEMFLDFKRAERPGRSISEENLPHMFEHWAR 245 Query: 189 WIA----LAGAVLPPENARRLTFTTYT-RRPAQSPHRVVGVL 225 +++ + AV PP+ + F R A +P V VL Sbjct: 246 YLSYLQVIQRAVAPPK----MRFANTVAPRDAVAPVEVDLVL 283
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 61.4 bits (149), Expect = 3e-12 Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 14/134 (10%) Query: 25 VDDGKSTLVGRLLHDSKSVLTDQLEAVEHASRSRGQEAPDLALLTDGLRAEREQGITIDV 84 VD GK+TL LL++S ++ +L +V +R TD ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAI--TELGSV-DKGTTR----------TDNTLLERQRGITIQT 58 Query: 85 AYRYFATPRRRFILADTPGHVQYTRNMVTGASTAELAVVLVDARNGVVEQTRRHAAVAAL 144 F + + DTPGH+ + + S + A++L+ A++GV QTR Sbjct: 59 GITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRK 118 Query: 145 LRVPHVVLAVNKMD 158 + +P + +NK+D Sbjct: 119 MGIPTIFF-INKID 131
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 225 bits (575), Expect = 7e-68 Identities = 114/318 (35%), Positives = 161/318 (50%), Gaps = 40/318 (12%) Query: 224 VPQVNAPQAWAEGYDGKGSTVAVLDTGIDATHPDVKDRILETKSFVPGEE-----VLDKH 278 V + AP W + G+G VAVLDTG DA HPD+K RI+ ++F +E D + Sbjct: 26 VEMIQAPAVWNQTR-GRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYN 84 Query: 279 GHGTHVASTIAGSGAASEGVNKGVAPGADLIIGKVLSNEGSGADSGIIEAMEWAKAEGAD 338 GHGTHVA TIA + + V GVAP ADL+I KVL+ +GSG II+ + +A + D Sbjct: 85 GHGTHVAGTIAATENENGVV--GVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD 142 Query: 339 VVSMSLGSSIPDDGSDPMSQAVDALSADGGPLFVIAAGNAYGAG----TIGSPGSAEKAL 394 ++SMSLG + + +AV A L + AAGN +G PG + + Sbjct: 143 IISMSLG---GPEDVPELHEAVKKAVASQI-LVMCAAGNEGDGDDRTDELGYPGCYNEVI 198 Query: 395 TVAAVDKQDNRAGFSSMGPLVRSYGLKPDLSAPGVDINAAASQAVPGVSGMYRTMSGTSM 454 +V A++ + + FS+ + DL APG DI + VPG G Y T SGTSM Sbjct: 199 SVGAINFDRHASEFSNSNN-------EVDLVAPGEDILS----TVPG--GKYATFSGTSM 245 Query: 455 ATPHVAGAAAILKQR-----HPDWSGGRIKDALMSSSKKLDAYTPYEQGTGRLDVKAAVD 509 ATPHVAGA A++KQ D + + L+ + L +P +G G L + A + Sbjct: 246 ATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPL-GNSPKMEGNGLLYLTAVEE 304 Query: 510 -----TTIEATGSVAVAS 522 T G ++ AS Sbjct: 305 LSRIFDTQRVAGILSTAS 322
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.0 bits (70), Expect = 0.009 Identities = 16/50 (32%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 290 SWRTPNRVRLPVPAAGLGV--AMVVAGMSPNVYVLVAMVTAAGVFVAPAL 337 SW P V L VP +GV A + +VY +V ++T G+ A+ Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAI 942
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 29.6 bits (66), Expect = 0.026 Identities = 12/55 (21%), Positives = 24/55 (43%), Gaps = 2/55 (3%) Query: 383 TLEMAASWTDLPVIYDEVVDAIQSVPGTLAASAHQSHAYTDGACVYFSLRGDVAP 437 LE AA V+ D ++D +Q+ P + ++ + C ++R +A Sbjct: 189 ALEYAAGRCAFTVMTDSLLDQLQNAPADVQKTSANTGKKNVFTCE--NIRKQIAE 241
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 45.6 bits (108), Expect = 3e-07 Identities = 27/82 (32%), Positives = 40/82 (48%), Gaps = 1/82 (1%) Query: 68 ILTATAPALAIIFNPVGGWLATRIGRVPPLLIAKVFAIAGALLAAFAGDFTVVWLGRVLV 127 IL A + PV G L+ R GR P LL++ A + A A V+++GR++ Sbjct: 47 ILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVA 106 Query: 128 GVAYGIDFAVAMALLAEYTPAK 149 G+ G AVA A +A+ T Sbjct: 107 GIT-GATGAVAGAYIADITDGD 127
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 265 bits (679), Expect = 1e-77 Identities = 118/600 (19%), Positives = 214/600 (35%), Gaps = 80/600 (13%) Query: 121 KPVKADKQSSAAAGDECGDISGVINATGSALVQQLKALPRITCTYPLFSLTGEDARKTF- 179 +P+ S A ++ + S LV+ +K + LF+ D TF Sbjct: 76 RPLGPSIAPSRARNNKIYTFDELNRMNYSDLVELIKTI-SYENVPDLFNFN--DGSYTFF 132 Query: 180 -REAQMVTVANALRDASATYSGNNSAAIGQLVLFLRAGYYVQDNHANVVGDYGTALDSAA 238 ++ + L D+ TY+ ++ I LV FLRAGYY+ + + L + Sbjct: 133 SNRDRVQAIIYGLEDSGRTYTADDDKGIPTLVEFLRAGYYLGFYNKQLSYLNTPQLKNEC 192 Query: 239 LGALDAFFASPHSKDVTDANGEIFNEVVTLIDSAHAAGRYAGVVKWMLGSY------DGT 292 L A+ A + + + T A + + LI +A A ++L + G+ Sbjct: 193 LPAMKAIQYNSNFRLGTKAQDGVVEALGRLIGNASADPEVINNCIYVLSDFKDNIDKYGS 252 Query: 293 WPSQMN---LAMQHVEWVVEN------GFKAKNDDRGWRAALKADPTILNTWAGFITRNS 343 S+ N M+ +++ + G+ AKN + + + L + + + Sbjct: 253 NYSKGNAVFNLMKGIDYYTNSVIYNTKGYDAKNTE--FYNRIDPYMERLESLCTIGDKLN 310 Query: 344 AQLNRLDVVSNVGRYLGYALDVPELKDRVRPLLKDLINRYPNVGPTAPITMNLGWYTRQY 403 + +V+N Y G E + L+ + YP ++ Sbjct: 311 N--DNAWLVNNALYYTGRMGKFREDPSISQRALERAMKEYPY------LSYQYIEAANDL 362 Query: 404 DRNNCAAYAIC----------DLGDRVLPAILPIQHTCTPDLKI-RAQD-MSPGQLAGTC 451 D N + D ++ LP +T + +A D ++ ++ Sbjct: 363 DLNFGGKNSSGNDIDFNKIKADAREKYLPK----TYTFDDGKFVVKAGDKVTEEKIKRLY 418 Query: 452 TSLVNQDAYFHRVIGDKGA-IPGDVNTNLEVVVFDDYTQYSLYAWAIYNIDVDNGGMYEE 510 + A F RV+ + A G+ + L VV+++ +Y L I DNGG+Y E Sbjct: 419 WASKEVKAQFMRVVQNDKALEEGNPDDILTVVIYNSPEEYKLNR-IINGFSTDNGGIYIE 477 Query: 511 GNPAAAGNQARFIAHEAHWLRPDFQIWNLN----HEYTHYLDGRYN---MAGDFEASLTT 563 N F +E P+ I+ L HE+THYL GRY M G E Sbjct: 478 -------NIGTFFTYER---TPEESIYTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEG 527 Query: 564 PTIWWVEGIAENISYGYRNE----RNADAIGEAGKKTYK--LSDLFDTVYNQDGDPEVNS 617 W+ EG AE + R + R + G A + + L + Y S Sbjct: 528 VLTWYEEGTAEFFAGSTRTDGIKPRKSVTQGLAYDRNNRMSLYGVLHAKYG--------S 579 Query: 618 NRVYRWGFLAVRYMLQAHPADVETVLNKYRTGDWNGARTFLKQTIGTSY-DAGFATWLTT 676 Y +GF YM + + N + D +G + ++ + + ++ + Sbjct: 580 WDFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDS 639 Score = 73.2 bits (179), Expect = 3e-15 Identities = 26/168 (15%), Positives = 51/168 (30%), Gaps = 28/168 (16%) Query: 535 QIWNLNHEYTHYLDGRYNMAGDFEASLTTPTIWWVEGIAENISYGYRNERNADAIGEAGK 594 + LN +Y Y+D N + + L + + A++I+ + + I + Sbjct: 625 SDYGLNDKYQDYMDSLLNNIDNLDVPLVS-DEYVNGHEAKDINEITNDIKEVSNIKDL-- 681 Query: 595 KTYKLSDLFDTVYNQDGDPEVNSNRVYRWGFLAVRYMLQAHP-----ADVETVLNKYRTG 649 + F T Y+ R ++ R + + + + +L + Sbjct: 682 SSNVEKSQFFTTYD------------MRGTYVGGRSQGEENDWKDMNSKLNDILKELSKK 729 Query: 650 DWNGARTFLKQ--------TIGTSYDAGFATWLTTVCATNDCGPLPEA 689 WNG +T YD F T P+A Sbjct: 730 SWNGYKTVTAYFVNHKVDGNGNYVYDVVFHGMNTDTNTDVHVNKEPKA 777
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.2 bits (133), Expect = 3e-11 Identities = 27/118 (22%), Positives = 43/118 (36%), Gaps = 3/118 (2%) Query: 5 IRLLLADDHPVVRAGLRAVLDSEPDFCVVAEAATAERAVELAATGEFDVVLMDLQFGAGM 64 +L+ADD +R L L V + A A G+ D+V+ D+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRWIAAGDGDLVVTDVVMP-DE 60 Query: 65 HGSRATAAITARPDGPRVLILTTYDSDADILAAVEAGAAGYLLKDAPPEELAAAVRTA 122 + I VL+++ ++ + A E GA YL K EL + A Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 39.0 bits (91), Expect = 4e-05 Identities = 36/168 (21%), Positives = 59/168 (35%), Gaps = 37/168 (22%) Query: 6 VNLVLRSTRVVTPDGTRPAAVAVADGRI---------------DAVLPYGTEVPAGARSE 50 V+ V+ + ++ G A + + DGRI ++ GTEV AG Sbjct: 68 VDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGK- 126 Query: 51 DFGDDVLLPGLVDTHVHVNDPGRTEWEGFRTATRAAAAGGITTLLDM---PLNSLPPTTS 107 ++ G +D+H+H P + E A G+T +L P + TT Sbjct: 127 -----IVTAGGMDSHIHFICPQQIE---------EALMSGLTCMLGGGTGPAHGTLATTC 172 Query: 108 VA---HLRTKQQVAAPKAHIDTGFWGGAIPSNVKDLRPLYEAGVFGFK 152 H+ + AA ++ F G S L + G K Sbjct: 173 TPGPWHIARMIE-AADAFPMNLAFAGKGNASLPGALVEMVLGGATSLK 219
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 106 bits (265), Expect = 1e-29 Identities = 79/252 (31%), Positives = 113/252 (44%), Gaps = 19/252 (7%) Query: 14 RAALVTGGSRGIGAATALRLARDGADVALTYVRDEDGAQAVVKEIQSYGRRGIALRADSA 73 + A +TG ++GIG A A LA GA +A E + VV +++ R A AD Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEK-LEKVVSSLKAEARHAEAFPADVR 67 Query: 74 DPDAAPAAVRRAADTLGRLDILVNNAGIGVLGPIESLTPADVDRVLAVNVRAVFLACRTA 133 D A R +G +DILVN AG+ G I SL+ + + +VN VF A R+ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 134 AGLMGD--GGRIISLGTALSRHAGGP--GSTLYTMSKSALAGLTKPLARELGPRGITVNL 189 + M D G I+++G S AG P Y SK+A TK L EL I N+ Sbjct: 128 SKYMMDRRSGSIVTVG---SNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 190 VQPGPVDTDL-------NPADGPLAAGQLS----ATALDRFGSVDEVASLIAYLASDEAA 238 V PG +TD+ + G L L + ++A + +L S +A Sbjct: 185 VSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAG 244 Query: 239 YITGTEVTVDGG 250 +IT + VDGG Sbjct: 245 HITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 38.7 bits (90), Expect = 3e-05 Identities = 61/275 (22%), Positives = 101/275 (36%), Gaps = 15/275 (5%) Query: 41 GLLTSAFAIGMVVGAPLMALFSRNWPRRRALLFFLCVFSAVHVIGALTPSYGVLLATRVV 100 G+L + +A+ AP++ S + RR LL L + + I A P VL R+V Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 101 GALANAGFWAVALVTAVSMVGPEARARATSVVVGGVTIACVAGVPAGAALGGHWGWRSAF 160 + A AVA + + RAR + VAG P L G + + F Sbjct: 106 AGITGATG-AVAGAYIADITDGDERARHFGFMSACFGFGMVAG-PVLGGLMGGFSPHAPF 163 Query: 161 WAVALVSVPAVVVIARTIPGARPKATPAPARDELGALARPR-------LLLTLLTSALVQ 213 +A A ++ + +P + R+ L LA R + + ++Q Sbjct: 164 FAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQ 223 Query: 214 GATFCAFSYFEPLATHVTGFGAAWVPALLALFG-LGSFVGVTVAGRIIDARPVALTTAGL 272 + + + A + LA FG L S + G + A + A + Sbjct: 224 LVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPV--AARLGERRALM 281 Query: 273 LSLAVGWTGFALTAGSPFATVALVFVQGMLAFGTG 307 L + TG+ L A FAT + M+ +G Sbjct: 282 LGMIADGTGYILLA---FATRGWMAFPIMVLLASG 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 90.7 bits (225), Expect = 3e-23 Identities = 33/164 (20%), Positives = 68/164 (41%), Gaps = 6/164 (3%) Query: 2 PRVLLIEDDPSVREGVELGLRRRGHELRSVETGEEGLAALGEFRPDLVLLDLMLPGMNGV 61 +L+ +DD ++R + L R G+++R + DLV+ D+++P N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QVCRLIRET-SQLPIIMLTARGDDFDVVVGLEAGADDYIVKPARTEVIEARIRAVL---R 117 + I++ LP+++++A+ + E GA DY+ KP + I L + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 118 RLAEPAGRGGIEFHGELAVDRAGLSVAKAGQRLLLAPSELKLLL 161 R + + A + + R L ++L L++ Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR--LMQTDLTLMI 165
>PF06580#Sensor histidine kinase Length = 349 Score = 42.2 bits (99), Expect = 3e-06 Identities = 43/264 (16%), Positives = 91/264 (34%), Gaps = 60/264 (22%) Query: 230 LAELAWTFNESSTKLQESVEELQRAEARARRFASDVSHELRTPLAGMLAVTEVLDEDAAQ 289 + W+ ++ ++ + + + A + +L L AQ Sbjct: 126 VVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQEA--QLM-----ALK---------AQ 169 Query: 290 LNA----DTAAAVR-LISAETGKLATLVEDLMEISRFDAKAADLHL----DEVDVAETIR 340 +N + +R LI + K ++ L E+ R+ + ++ DE+ + Sbjct: 170 INPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADEL---TVVD 226 Query: 341 K--TLQGRHWEDRVRTEL--PDGIRAMLDPRRFDIVVANLVGNALRHGAQPV----TVRL 392 L +EDR++ E I + P ++V LV N ++HG + + L Sbjct: 227 SYLQLASIQFEDRLQFENQINPAIMDVQVPP---MLVQTLVENGIKHGIAQLPQGGKILL 283 Query: 393 RTERRGAARWLVTEVADNGPGIDPAVLPHIFDRFYKADAARTRSAGSGLGLAITQENVR- 451 + + + EV + G A + +G GL +E ++ Sbjct: 284 KGTKDNG--TVTLEVENTGSL-----------------ALKNTKESTGTGLQNVRERLQM 324 Query: 452 LHGGTVR-AVNGPAGGAVLTVELP 474 L+G + ++ G V +P Sbjct: 325 LYGTEAQIKLSEKQGKVNAMVLIP 348
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 160 bits (406), Expect = 2e-44 Identities = 104/424 (24%), Positives = 185/424 (43%), Gaps = 22/424 (5%) Query: 51 ATPRHIRLVFLGLMLTLLLAALDQMIVATALPKIVGELHGLE-KMSWAVTAYLLASTIGL 109 + RH +++ L + + L++M++ +LP I + + +W TA++L +IG Sbjct: 8 SNLRHNQILIW-LCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGT 66 Query: 110 PIYGKLGDLFGRKGVFQFAIVVFVIGSALAGWSRTMDE-LIAFRAVQGIGGGGLMIGVQA 168 +YGKL D G K + F I++ GS + + LI R +QG G V Sbjct: 67 AVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMV 126 Query: 169 IIADVVPPRERGRFMGLIGAAFGLASVAGPLLGGFFTDHASWRWCFYINVPFGLITLAVI 228 ++A +P RG+ GLIG+ + GP +GG + W + + +P +IT+ + Sbjct: 127 VVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY--IHWSYLLLIP--MITIITV 182 Query: 229 TVVLKLPRPTVRPR--LDILGALLLAAASTCLVLLTSWGGTEYAWGSRTILGLAAGAAGT 286 ++KL + VR + DI G +L++ +L T T Y+ + L+ Sbjct: 183 PFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFT----TSYSISFLIVSVLSFL---- 234 Query: 287 ALLFVVVEHRAAEPIIPLRLFRDSIFNVTALVGAVVGVALFGAASYLPTFLQMVDGATAT 346 +FV + +P + L ++ F + L G ++ + G S +P ++ V + Sbjct: 235 --IFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTA 292 Query: 347 ESG-LLMLPMMGGIVGASVVSGQLISRTGRYRVYPILGGAVSVVGMWLLSRLETDTPRFE 405 E G +++ P ++ + G L+ R G V +G V S L T F Sbjct: 293 EIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVL-NIGVTFLSVSFLTASFLLETTSWFM 351 Query: 406 YSIAQAVLGIGIGLVMPVLVLAVQNSVEPADLGAATSANNYFRQIGGSVGAAVFGTLFAG 465 I VLG G+ V+ V +S++ + GA S N+ + G A+ G L + Sbjct: 352 TIIIVFVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410 Query: 466 RLAD 469 L D Sbjct: 411 PLLD 414
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 69.6 bits (170), Expect = 8e-17 Identities = 46/204 (22%), Positives = 79/204 (38%), Gaps = 14/204 (6%) Query: 17 VTLDAILDAATEIADDRGLDAVTFRVVADRLGVSPMAIHRTTGGIDALQHALVSRIVGE- 75 + ++++DAA E+ ++ G+D +T R +A +LG+ ++ AL AL I+ Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 76 VTRSVHWP-DDWCGVVRLFADTLHDLLMRHPVILEAH--RRASLVGPGADDVALRVVDAL 132 S+ + W +R A + L+R+ + H R + LR + Sbjct: 64 HDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGTRPDEKQYDTVETQLRF---M 120 Query: 133 RTAGLDEEGAVYAYGALHDFVTG-------HVAIRLGRGDPEQLRLPPERRAMSVFADHH 185 G +YA A+ F G H A R LPP R D Sbjct: 121 TENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDENLPPLLREALQIMDSD 180 Query: 186 DYDRRFAYGLDLVIGGIAAAAAPV 209 D ++ F +GL+ +I G + Sbjct: 181 DGEQAFLHGLESLIRGFEVQLTAL 204
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 31.3 bits (70), Expect = 0.006 Identities = 42/157 (26%), Positives = 64/157 (40%), Gaps = 15/157 (9%) Query: 232 ADALQASDAELRVQEAKARRFVADVSHELRTPLAAMTMVATVLEEDADQLPPDAARAARA 291 A L+ AE + Q+A + + E +T L A+ V A +L A AAR Sbjct: 77 AQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVI------ASRLMQMALEAARQ 130 Query: 292 VGAET-----ARLSRLVEDLMEISRFDAKAVRLNAAETDLA---DTVRASLALRGWTDRV 343 V +T + L + ++ L++ + +L DL D + A+L+L GW R Sbjct: 131 VIGQTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRG 190 Query: 344 QTHLHE-GVRAVVDRRRIDVIVANLVGNALRHGAPPV 379 LH G + D +D VA R AP V Sbjct: 191 DPTLHPGGCKVSADEGDLDASVATRWQELCRLAAPGV 227
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 97.6 bits (243), Expect = 9e-26 Identities = 39/140 (27%), Positives = 63/140 (45%), Gaps = 5/140 (3%) Query: 2 PHVLLIEDDASVRDGMELVLRRHGYGVDTAATGEQALALLAGERGSRVELAVLDLMLPGM 61 +L+ +DDA++R + L R GY V + +A G L V D+++P Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD---LVVTDVVMPDE 60 Query: 62 DGFEVCRRIRARSATLPVIMLTARGDDSDIVTGLEAGADDYVVKPVTAPVLEARIRAAL- 120 + F++ RI+ LPV++++A+ + E GA DY+ KP L I AL Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 -RRAEPSARQRSDADLAGLV 139 + PS + D LV Sbjct: 121 EPKRRPSKLEDDSQDGMPLV 140
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 29.7 bits (66), Expect = 0.022 Identities = 19/96 (19%), Positives = 33/96 (34%) Query: 79 VTVAASEGKTLTMGQALYELNDKPVTLLYGPVPMFREMKAGDRGSDVLQLERNLRDLGYG 138 +TV + G T + + + DKPV ++ P KA + ++ L + Y Sbjct: 837 LTVTDNNGGINTESKKIKVVEDKPVEVINESEPNNDFEKANQIAKSNMLVKGTLSEEDYS 896 Query: 139 ANLYVDARYDENTEAAVKQWQKSLNRETTGKVGKGD 174 Y D N + + T K G + Sbjct: 897 DKYYFDVAKKGNVKITLNNLNSVGITWTLYKEGDLN 932
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 30.5 bits (69), Expect = 0.005 Identities = 24/101 (23%), Positives = 40/101 (39%), Gaps = 18/101 (17%) Query: 89 GRPAEQLGPLIEIIEETVRDITAVGRPWEVQVIGSLDMLPGVSARVLKQAAAATAGRGGL 148 G A+Q+ + T +I A+ RP + VI + + +KQ + + R Sbjct: 56 GHDAKQM------LGRTPGNIAAI-RPMKDGVIADFFVTEKMLQHFIKQVHSNSFMRPSP 108 Query: 149 KVDVAVGYGG----RREIVDAVKSAFKEHIAAGGDPAELVE 185 +V V V G RR I ++ + AG L+E Sbjct: 109 RVLVCVPVGATQVERRAIRESAQG-------AGAREVFLIE 142
>INTIMIN#Intimin signature. Length = 939 Score = 30.8 bits (69), Expect = 0.027 Identities = 45/263 (17%), Positives = 77/263 (29%), Gaps = 48/263 (18%) Query: 215 APIVVNEVGTHTIRYRATDKAGNTAAEKSVGFAVAAPPTDDRTPPETSATVSGEKDDQGR 274 VV++VG T + + V P + VSG Sbjct: 551 NGQVVDQVGVTDFTADKTSAKADGTEAITYTATVKKNGVAQANVPVSFNIVSGTAV---- 606 Query: 275 YLGMATVTVTASDTGSGVNTIEYATGTDGAWQPYTAPVMVHETGTHQVRYRATDKAGNAA 334 +A+ GSG T+ + G QV A +A Sbjct: 607 -----LSANSANTNGSGKATVTLKSDKPG-----------------QVVVSAKTAEMTSA 644 Query: 335 AEKSVDFTVVAPPTQDKTPPETSAEVEGDKN---SDNAYITSAEVTVTATDAGSGVDKVE 391 + + T+ + E++ DK ++ + V V D +V Sbjct: 645 LN--ANAVIFVDQTK-----ASITEIKADKTTAVANGQDAITYTVKVMKGDKPVSNQEVT 697 Query: 392 YSLDGGPYLAYTTTVIVDRVGYHTVAHRATDKAGNASVAKQVSFTVAESGGVPAPNCPEF 451 ++ G +T D GY V +T G + V+ +VS + V AP F Sbjct: 698 FTTTLGKL--SNSTEKTDTNGYAKVTLTSTTP-GKSLVSARVS---DVAVDVKAPEVEFF 751 Query: 452 DE------RLTVIVGTVDTGVPN 468 + ++ V +P Sbjct: 752 TTLTIDDGNIEIVGTGVKGKLPT 774
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 35.0 bits (80), Expect = 4e-04 Identities = 14/85 (16%), Positives = 25/85 (29%), Gaps = 3/85 (3%) Query: 321 THEKPAQEKPAQEKPAQEKPAQEKPAQDKPAQDKPAQDKPAPDKTAPDKTAPDKTAPDK- 379 A + P + E + P K A +KP P K P + Sbjct: 60 LEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAP--VVIEKPKPKPKPKPKPVKKVEQPKRD 117 Query: 380 TASGDTVPGKTAKESAAHDPAAHGS 404 ++ P + +A P + + Sbjct: 118 VKPVESRPASPFENTAPARPTSSTA 142
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 162 bits (411), Expect = 1e-49 Identities = 78/342 (22%), Positives = 142/342 (41%), Gaps = 38/342 (11%) Query: 1 MTWLITGGAGYIGAHVVRSMVGAGERVVVLDDLST--------GVVERLP-ADVPLIRGS 51 M +L+TG AG+IG HV + ++ AG +VV +D+L+ +E L + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 AADRALLDRVLAQYDVTGVVHLAAKKQVGESVEKPLLYYRENMAGLTVLLEAVVAAGVRR 111 ADR + + A V + V S+E P Y N+ G +LE ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 112 FLFSSSAAVYGV-PDVELITEDTPCVPINPYGETKLAGEWLVRATGRAHSLSTGCLRYFN 170 L++SS++VYG+ + T+D+ P++ Y TK A E + + L LR+F Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFT 180 Query: 171 VAG-AATPELSDTGVFNVIPMFFDRLTRGEAPRIFGDDYATPDGTCIRDYIHVADLADAH 229 V G P++ + F + G++ ++ G RD+ ++ D+A+A Sbjct: 181 VYGPWGRPDM-------ALFKFTKAMLEGKSIDVYN------YGKMKRDFTYIDDIAEAI 227 Query: 230 LAVARRLAEQDAGDLT--------------VNIGRGEGVSVRELAGLVGEVSGRPEKPEI 275 + + + D NIG V + + + + G K + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 276 EARRPGDAAKAVASAVRMSEELGWTARRGVREMVESAWQGWR 317 +PGD + A + E +G+T V++ V++ +R Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYR 329
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 34.5 bits (79), Expect = 3e-04 Identities = 22/107 (20%), Positives = 41/107 (38%), Gaps = 4/107 (3%) Query: 168 VLAVVAVAFGSYPGPSWLLIIPALVMQFLFNTGLAMIMARLGSKTPDLAQLMPFVMRTWM 227 + VVA A G S L +P + + L L M++ L V+ + Sbjct: 131 GIGVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPIL 190 Query: 228 YASGVMFSIPVMLKDKPDWIANVLQYNPAAIYMDLIRFALIDGYGSE 274 + SG +F + + P ++ P + +DLIR ++ + Sbjct: 191 FLSGAVFPVDQL----PIVFQTAARFLPLSHSIDLIRPIMLGHPVVD 233
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 40.5 bits (94), Expect = 2e-05 Identities = 34/127 (26%), Positives = 45/127 (35%), Gaps = 21/127 (16%) Query: 356 LGVDGDAPAEADAALVP----PPGPVHRPPAEDGTGSHRRPNPTLNPGPGAGPGPSPAAS 411 G D D ++P PG P A+ NP NP P PG P Sbjct: 295 FGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPE 354 Query: 412 PAPQASANRQPYV----------PTQPLRLHQPHQQARREGEAP-------PLPLRAERL 454 P P + + P P P R + H++ R+EGE P L +RL Sbjct: 355 PDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKERKEGEDGGLLCKFFPDILACDRL 414 Query: 455 DRPTPAD 461 P PA+ Sbjct: 415 PEPNPAE 421
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 29.7 bits (67), Expect = 0.014 Identities = 16/64 (25%), Positives = 23/64 (35%), Gaps = 7/64 (10%) Query: 249 YTAAPLALL----DRALRIKAVTEGHGVPLRAAALHYPLAHPAVAGVLVGTRSPDEVRDA 304 T PL + ++ + E GVP+ PLA LV P E +A Sbjct: 277 ETPLPLVTFKYTDAQVQTVRKIAEEEGVPILQRI---PLARALYWDALVDHYIPAEQIEA 333 Query: 305 AALL 308 A + Sbjct: 334 TAEV 337
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.7 bits (116), Expect = 9e-09 Identities = 29/143 (20%), Positives = 49/143 (34%), Gaps = 15/143 (10%) Query: 3 RVLAVDDEEPALEEL-LYLLRADPRIRSAEGATGATEALRRIGGAVDAGPDDPSAIDVVF 61 +L DD+ L L RA +R A + G D+V Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG------------DLVV 52 Query: 62 LDIHMAGLTGLDVAQLLAGFAAPPLIVFVTAHEGF--AVHAFDLKAVDYVLKPVRRERLA 119 D+ M D+ + ++ ++A F A+ A + A DY+ KP L Sbjct: 53 TDVVMPDENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELI 112 Query: 120 EAVRRVAEQVGDRSAPVLDTAND 142 + R + R + + D + D Sbjct: 113 GIIGRALAEPKRRPSKLEDDSQD 135
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 25.9 bits (57), Expect = 0.042 Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 13/73 (17%) Query: 35 TALGGAYVRSLMRSQLRAGLTAFTVLAAVVGTLPLVFEALHSAAL------VWAVLGFAA 88 A+ V + QL+ L A T L ++VG PL+F A+++A++ W + G A Sbjct: 321 QAMLSRQVDEERQGQLQGSLAALTSLTSIVG--PLLFTAIYAASITTWNGWAW-IAGAAL 377 Query: 89 Y----PPLTLAAW 97 Y P L W Sbjct: 378 YLLCLPALRRGLW 390
>PF06580#Sensor histidine kinase Length = 349 Score = 212 bits (540), Expect = 2e-67 Identities = 70/229 (30%), Positives = 114/229 (49%), Gaps = 26/229 (11%) Query: 175 QLELAELDRSR--TQLIEAEIRALRAQISPHFIFNSLAAIASFVRTDPEQARELLLEFAD 232 + AE+D+ + + EA++ AL+AQI+PHF+FN+L I + + DP +ARE+L ++ Sbjct: 143 NYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSE 202 Query: 233 FTRYSFR-SHGDFTTLADELHSIDQYLALVRARFGERLAVTLQVAPEVLPVALPFLCLQP 291 RYS R S+ +LADEL +D YL L +F +RL Q+ P ++ V +P + +Q Sbjct: 203 LMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQT 262 Query: 292 LVENAVKHGLEGAVTLPRAPGSVRAGETPTRITIRALDAGSEAEVVIEDDGTGMDPQRLR 351 LVEN +KHG+ +I ++ + +E+ G+ Sbjct: 263 LVENGIKHGIAQL-------------PQGGKILLKGTKDNGTVTLEVENTGSLALK---- 305 Query: 352 RILRGEGGKSTGIGLLNVDERLRQVYGDDYGLVIETGIGAGMKVTVRLP 400 +STG GL NV ERL+ +YG + + + G V +P Sbjct: 306 -----NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKV-NAMVLIP 348
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 51.2 bits (122), Expect = 3e-10 Identities = 13/61 (21%), Positives = 14/61 (22%), Gaps = 2/61 (3%) Query: 58 AGPAPEPTPPPAPPPPPPPPPPPPPPPPPPPLPAPPPLAPPRPKPEPVPPPPSPTPSVRP 117 A A E A P P P P KP P T P Sbjct: 449 AKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAP--QAGTKPNQNKAPMKETKRQLP 506 Query: 118 T 118 + Sbjct: 507 S 507
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.8 bits (147), Expect = 1e-13 Identities = 26/174 (14%), Positives = 58/174 (33%), Gaps = 2/174 (1%) Query: 2 PKQVDHADRRRRIAEAVCRLADERGLEGVTLRDVAACAQVSMGAVQRCFRTKEEMLVFAL 61 + + + R+ I + RL ++G+ +L ++A A V+ GA+ F+ K ++ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 62 GYIGERISERVQARLVRCPAQSAAT--ALGHAVTEVSLLQEEHRAEARVWLAFVAQAAVS 119 I E + P + + V E ++ +E R + Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 120 EALARTLKANYAALQEAFTRLISEAGEGADCAVPLDPQREARTLLALADGLTAH 173 + + + + + + E L +R A + GL + Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMEN 177
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.002 Identities = 10/50 (20%), Positives = 17/50 (34%) Query: 18 VKAEYRGRGVSIAMKTFGMGFVRMCGARTIRTFHHPANTSAIAMNRTMGF 67 V +YR +GV A+ + + + + N SA F Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHF 146
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 67.9 bits (166), Expect = 9e-14 Identities = 51/226 (22%), Positives = 86/226 (38%), Gaps = 21/226 (9%) Query: 487 RIDLYPTADPQSQQARDLASGPVRAAV---AQHTPAGTTAHVGGTAAIYADISTAVDHDL 543 R + P+ + Q + A +SG A + A PAG G + Sbjct: 817 RYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQ----A 872 Query: 544 KIVFPVAAALIALILLLLLRSLLAPVILMLSVGLGFAATLGAATLLFQHVLGKPGVNFSL 603 + ++ ++ L L L S PV +ML V LG L AATL + Sbjct: 873 PALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLF--------NQKNDV 924 Query: 604 P-LVLFLFVVALGTDYNILISDRIREEMQRPG-PARAAVARA-VQHTTPAIATAGLVLAG 660 +V L + L ILI + ++ M++ G A A P + T+ + G Sbjct: 925 YFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILG 984 Query: 661 SFAT-LATTPGNE-QIAFATT-LGILLSALVLSLVLVPALTALLGR 703 ++ G+ Q A +G ++SA +L++ VP ++ R Sbjct: 985 VLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR 1030 Score = 53.3 bits (128), Expect = 3e-09 Identities = 56/298 (18%), Positives = 111/298 (37%), Gaps = 46/298 (15%) Query: 204 MGLILLINVLVFRSVLAALLPLVAVAMIIGVAGGAVAGAAILTGRKLDAGTPDLISVVL- 262 + L+ L+ L +++ A L+P +AV +++ +A G ++ T + +VL Sbjct: 348 IMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILA----AFGYSINTLT--MFGMVLA 401 Query: 263 LGIGIDYLLFLL---FRFREQLRARPEQSAREAAGQVSGRVGTAITSAALTIVAGF---A 316 +G+ +D + ++ R + + P+++ ++ Q+ G A+ A+ + A F A Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQG----ALVGIAMVLSAVFIPMA 457 Query: 317 TLGVATFGQFRSLGPAIAVAVLVMLLGSLTLLPALLAAAGRKMFWPSKALGHEPDEGRAA 376 G +T +R I A+ + +L +L L PAL A + P A HE G Sbjct: 458 FFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCA----TLLKPVSAEHHENKGGFFG 513 Query: 377 RFG--------------ARVARRPMTMTFASVALLAALAAGLIGI------RMDYGQGNA 416 F ++ ++A + + + D G Sbjct: 514 WFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLT 573 Query: 417 AAKTPAAATATEISRAL-----PAGVSDPTSVFVTATDGGTLTAGRLDGLSRALTQVK 469 + PA AT + L ++ +V T G +G+ A +K Sbjct: 574 MIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLK 631
>PF06580#Sensor histidine kinase Length = 349 Score = 32.1 bits (73), Expect = 0.004 Identities = 18/88 (20%), Positives = 33/88 (37%), Gaps = 13/88 (14%) Query: 311 NARKYA-----GPARASVRLTYRQDRVTVEVRDDGGSTPPQEGASSVGSGGYGLIGMRER 365 N K+ + ++ T VT+EV + G S+ G GL +RER Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKEST----GTGLQNVRER 321 Query: 366 VALHGG---TLAVGPQADGGFAVVADLP 390 + + G + + + G + +P Sbjct: 322 LQMLYGTEAQIKLSEK-QGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 71.4 bits (175), Expect = 1e-16 Identities = 28/118 (23%), Positives = 44/118 (37%), Gaps = 2/118 (1%) Query: 9 PRIRVLIADDQPLVRRGLSLILSPDPSFEVVGEAEDGAQAVALARRLRPDVVVMDIRMPV 68 +L+ADD +R L+ LS ++V + A D+VV D+ MP Sbjct: 2 TGATILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPD 59 Query: 69 LDGVGATGELAATVPGCRVLALSTFDMDEYVVGALRAGACGFLPKDSSPEDLSTAIRT 126 + + P VL +S + + A GA +LPK +L I Sbjct: 60 ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 45.2 bits (107), Expect = 6e-08 Identities = 14/85 (16%), Positives = 31/85 (36%), Gaps = 1/85 (1%) Query: 18 AADGVEAVERARQLRPDVVLMDVRMPRLNGIEATWQLLAESAEPPKVVVITTFENDGYVT 77 ++ D+V+ DV MP N + ++ + P V+V++ Sbjct: 33 TSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIKKARPDLP-VLVMSAQNTFMTAI 91 Query: 78 AALSAGASGFVLKRLPVPQIAEAVR 102 A GA ++ K + ++ + Sbjct: 92 KASEKGAYDYLPKPFDLTELIGIIG 116
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 62.1 bits (151), Expect = 1e-12 Identities = 93/390 (23%), Positives = 150/390 (38%), Gaps = 31/390 (7%) Query: 3 LALLALAIGAFGIGTTEFVIMGVLPQVAGDFGVTIPAA---GWLVSGYALGVVFGAPLLT 59 + L +A+ A GIG +IM VLP + D + G L++ YAL AP+L Sbjct: 9 VILSTVALDAVGIG----LIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 60 VLGTKVSRKKMLMFLMTLFVIGNALSAIAPSFGVMLIGRIVSSLAHGAFFGIGSVVAAGL 119 L + R+ +L+ + + A+ A AP V+ IGRIV+ + G+ + A + Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYI-ADI 123 Query: 120 VAPEKKASAISLMFMGLTVANIVGVPGGTYIGQAAGWRVTFVIVAALGVIGFLGVAKLVP 179 +++A M + G G +G F AAL + FL L+P Sbjct: 124 TDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 180 ET----GRPDSVTVRTEFAAF------RNVQVWLAMAMTVLGYGGVFAAITYITPMMTEV 229 E+ RP A+F V +A+ + G V AA+ I + Sbjct: 183 ESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI--FGEDR 240 Query: 230 AGYTEGAVTWLLVLFGI-GMFLGNLLGGKFADR--RLMPMLLTTLAALTAALLLFTATAH 286 + + L FGI ++ G A R ++L +A T +LL AT Sbjct: 241 FHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRG 300 Query: 287 NKVLAAITLSLIGALGFATVPPLQKWVLDQASAAPTLASAANIGAFNLGNALAAWLGGVV 346 + L G +G +P LQ + Q G+ +L + +G ++ Sbjct: 301 WMAFPIMVLLASGGIG---MPALQAMLSRQVDEE---RQGQLQGSLAALTSLTSIVGPLL 354 Query: 347 IAAGLGYTSPNWVGAI-LSGTALLLALLAA 375 A + W G ++G AL L L A Sbjct: 355 FTAIYAASITTWNGWAWIAGAALYLLCLPA 384
>PF06580#Sensor histidine kinase Length = 349 Score = 42.9 bits (101), Expect = 1e-06 Identities = 18/83 (21%), Positives = 34/83 (40%), Gaps = 10/83 (12%) Query: 320 IIQESVTNVVRHA---RADACRVTVDYRA--GDLAIEVADRGRG--DGPASGTGYGLAGM 372 ++Q V N ++H ++ + G + +EV + G TG GL + Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNV 318 Query: 373 RERVALLHGE---FSAAPRPGGG 392 RER+ +L+G + + G Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKV 341
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 4e-20 Identities = 28/114 (24%), Positives = 47/114 (41%), Gaps = 2/114 (1%) Query: 4 RVALVDDQPLVRTALQMVITEAPDLEVVGQAGTGEEAVRLVAAVRPDLVVMDIRMPGMDG 63 + + DD +RT L ++ A +V R +AA DLVV D+ MP + Sbjct: 5 TILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 64 IEATRRITEGDDGPQVIVLTTFDDDDYVYGALRAGASGFLVKDMALDDILAAIR 117 + RI + V+V++ + A GA +L K L +++ I Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 54.1 bits (130), Expect = 8e-11 Identities = 26/113 (23%), Positives = 42/113 (37%), Gaps = 2/113 (1%) Query: 4 ILVVDDDALVRLGLVDLLSTDPELTVVAEAADGLAAVEQASGHRVDVALVDVRMPRMDGI 63 ILV DDDA +R L LS + A + D+ + DV MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAA--TLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 64 AATRRLRALPDPPRVITLTTFDLDEYVYDALAAGADGFLLKDTEPREIIRAVH 116 R++ V+ ++ + A GA +L K + E+I + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 30.3 bits (68), Expect = 0.005 Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 3/74 (4%) Query: 106 GQFGSLISELREVRYAPVHFDAAEDLSYWRARVADKVSVGATALTGPTADPSRR---VQL 162 G+ I L V+ A VH + + R + + SV T G D + V L Sbjct: 137 GELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQISAVVHL 196 Query: 163 VNAPGAEVGPGQIA 176 V++ A + PG + Sbjct: 197 VSSAVAGLPPGNVT 210
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 46.7 bits (111), Expect = 9e-08 Identities = 52/240 (21%), Positives = 83/240 (34%), Gaps = 18/240 (7%) Query: 66 LLAIFLGAWSDHQAHKRRLLILADLVRAAVLLSVPVAYLSGAVTLGQLYAVALLTGAAGV 125 A LGA SD RR ++L L A +V A ++ A L LY ++ G G Sbjct: 58 ACAPVLGALSDR--FGRRPVLLVSLAGA----AVDYAIMATAPFLWVLYIGRIVAGITGA 111 Query: 126 LFNTAYPPFFVRLVPRASYVDANSKLSASRSASYVAGPAIGGALVQ-ALTAPVTLA--VD 182 A + + +SA VAGP +GG + + AP A ++ Sbjct: 112 TGAVA-GAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALN 170 Query: 183 ALTFLASAVLISKVSVNEPPAASGSTTAPSLLRRARTGLSFVVRHPVLRAALGCAATVNF 242 L FL L+ + V+ A + + Sbjct: 171 GLNFLTGCFLL------PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQL 224 Query: 243 FTFVAGSGLIVLFANRSLGLSAGVIGIAF-GIGATGALLGAVFAPKISRRFGVGRSIVVG 301 V + L V+F A IGI+ G +L A+ ++ R G R++++G Sbjct: 225 VGQV-PAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLG 283
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 219 bits (559), Expect = 1e-65 Identities = 100/297 (33%), Positives = 142/297 (47%), Gaps = 34/297 (11%) Query: 221 QIGTPAAWEAGLSGKGVKVAVLDTGVDPAHPDLKDRVSETKSFIEGQE-----VADRNGH 275 I PA W G+GVKVAVLDTG D HPDLK R+ ++F + E D NGH Sbjct: 28 MIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGH 86 Query: 276 GTHVSSTVGGSGAASDGKEKGVAPGATLAVGKVLSDQGFGSESQIIAGMEWAAKDVHAKI 335 GTHV+ T+ + + GVAP A L + KVL+ QG G II G+ +A + I Sbjct: 87 GTHVAGTIAATENENGV--VGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQ-KVDI 143 Query: 336 VSMSLGSSQGSDGTDPMAQAVNTLSKDTGALFVIAAGNAGAPG----TIGSPGAADSALT 391 +SMSLG G + + +AV L + AAGN G +G PG + ++ Sbjct: 144 ISMSLG---GPEDVPELHEAVKKAVAS-QILVMCAAGNEGDGDDRTDELGYPGCYNEVIS 199 Query: 392 IGAVDSADRRASFSSQGPRLGDNALKPDLSAPGVDILAARSQLVSGSGPYTSMSGTSMAT 451 +GA++ + FS+ + DL APG DIL+ G Y + SGTSMAT Sbjct: 200 VGAINFDRHASEFSNSNN-------EVDLVAPGEDILSTVPG-----GKYATFSGTSMAT 247 Query: 452 PHVAGVAALLAEK-----HPDWSGQQLKDGLMSTSKQISGTSYEVGAGRVDVPSAIA 503 PHVAG AL+ + D + +L L+ + + + G G + + + Sbjct: 248 PHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEE 304
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.0 bits (78), Expect = 8e-04 Identities = 25/141 (17%), Positives = 54/141 (38%), Gaps = 8/141 (5%) Query: 194 RGVRYRAVYAPEALEWPGVLDDIRELVRHGEQARVL---PGLGIKLAIADRRLALMPLSL 250 + A+ +A WPG ++REL + L + ++ + R + + Sbjct: 336 KRFDQEALELMKAHPWPG---NVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPI 392 Query: 251 DLNDVRAAVIRPSTLLDALTGYWEMCWKQALPLNAPAEDPLGEEDRLVL--TLLVSGLKD 308 + R+ + S ++ + + ALP + + L E + ++ L + Sbjct: 393 EKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQ 452 Query: 309 EAIARQLGWSVRTMRRRISRL 329 A LG + T+R++I L Sbjct: 453 IKAADLLGLNRNTLRKKIREL 473
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 178 bits (453), Expect = 2e-51 Identities = 86/227 (37%), Positives = 117/227 (51%), Gaps = 26/227 (11%) Query: 183 VPLIGAPGVWQRKDPAGSRVTGKGTTVAILDSGVDYTHPDLGGGLGKGHKVVGGHDFVNG 242 V +I AP VW + G+G VA+LD+G D HPDL +++GG +F + Sbjct: 26 VEMIQAPAVWNQ-------TRGRGVKVAVLDTGCDADHPDLKA------RIIGGRNFTDD 72 Query: 243 DE----DPKDDNGHGTHVAGIIAGRAAEKGGVTGVAPGANLLAYKVMDADGSGYTSDIIA 298 DE KD NGHGTHVAG IA E G V GVAP A+LL KV++ GSG II Sbjct: 73 DEGDPEIFKDYNGHGTHVAGTIAATENENGVV-GVAPEADLLIIKVLNKQGSGQYDWIIQ 131 Query: 299 GVEAASDPANPHRADVINMSLGGPGDGTDPLGRAATAAVQAGVVVVAAAGNDGPG---TG 355 G+ A + D+I+MSLGGP D L A AV + ++V+ AAGN+G G T Sbjct: 132 GI----YYAIEQKVDIISMSLGGPEDV-PELHEAVKKAVASQILVMCAAGNEGDGDDRTD 186 Query: 356 TVSSPATADGVVAVGASTSNLRLPSAYLAGKKPELIQTYRGILSANP 402 + P + V++VGA + + + +L+ ILS P Sbjct: 187 ELGYPGCYNEVISVGAINFDRHASEFSNSNNEVDLVAPGEDILSTVP 233 Score = 80.7 bits (199), Expect = 4e-18 Identities = 42/117 (35%), Positives = 58/117 (49%), Gaps = 16/117 (13%) Query: 542 VTLRGTDTTDRIASFSSRGPAQDFGSKPDLVAPGVEIRSTVPKALYGPGQYRMSGTSMAA 601 +++ + + FS+ + DLVAPG +I STVP G SGTSMA Sbjct: 198 ISVGAINFDRHASEFSNSNN------EVDLVAPGEDILSTVP----GGKYATFSGTSMAT 247 Query: 602 PHVAGAAALLRQL-----HPGRTPAEIKAELIGTAKPLSGTGPTTQGSGRLDVAAAA 653 PHVAGA AL++QL T E+ A+LI PL + P +G+G L + A Sbjct: 248 PHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNS-PKMEGNGLLYLTAVE 303
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 37.2 bits (86), Expect = 8e-05 Identities = 33/157 (21%), Positives = 62/157 (39%), Gaps = 4/157 (2%) Query: 18 LRENWAQFTLLVIVTASVGSLVGLERTTVPLIGTDVFGLTSNLAVFSFIVAFGLAKALTN 77 LR N L ++ SV + + L ++P I D F + AF L ++ Sbjct: 10 LRHNQILIWLCILSFFSVLNEMVLN-VSLPDIAND-FNKPPASTNW-VNTAFMLTFSIGT 66 Query: 78 LAAGALTARFRRRQLLLAGWLIGVPVPFVLAWGPSWW-WVLAANVLLGVNQGMTWSMTVN 136 G L+ + ++LLL G +I + G S++ ++ A + G ++ + Sbjct: 67 AVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMV 126 Query: 137 MKIDLVGPARRGLATGLNEAAGYVAVGTTALLTGYLA 173 + + RG A GL + + G + G +A Sbjct: 127 VVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIA 163
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 122 bits (306), Expect = 7e-36 Identities = 78/253 (30%), Positives = 122/253 (48%), Gaps = 13/253 (5%) Query: 2 LTGRNAVVTGGSRGIGRAIVERLCRDGAHVVFNYATSDDAAEEVVRTVQDNGGKAWAIRL 61 + G+ A +TG ++GIG A+ L GAH+ + + E+VV +++ A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIA-AVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 62 DLADPDAPEQLMEAAEAQLGGLDILVNNAALCLTPSLIADTDPAVFDKVMTVNTRTVFMT 121 D+ D A +++ E ++G +DILVN A + L P LI ++ +VN+ VF Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 IRHAARRMRD--GGRIVNISTANTVRPGPGISAYAASKGAVEQLTTIAAHELGARGITVN 179 R ++ M D G IV + + P ++AYA+SK A T EL I N Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 180 TVSPGATDTDLLRG--TNQPQALEAVAGM-------TPLGRMGEPSDVADVVAFLAGHDG 230 VSPG+T+TD+ ++ A + + G PL ++ +PSD+AD V FL Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 231 RWITGQNVRATGG 243 IT N+ GG Sbjct: 244 GHITMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 123 bits (310), Expect = 1e-32 Identities = 93/421 (22%), Positives = 163/421 (38%), Gaps = 26/421 (6%) Query: 27 RRWQALAVCLIAGFMTLLDVSIVNVALPSIREGLHTPESDLQWVLSGYSLAFGLFLIPAG 86 R Q L I F ++L+ ++NV+LP I + P + WV + + L F + G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 87 RLGDARGRRVVFMAGLALFTLASAACGAAQSSL-WLVVARLVQGLAGGLISPQISALIQQ 145 +L D G + + + G+ + S S L++AR +QG + ++ + Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 146 MFSGQERGRAFGMFGSVVAISTAVGPLSGGLLIQAAGAEEGWRWVFYVNLPLGAVCLLLA 205 + RG+AFG+ GS+VA+ VGP GG++ W + + +P+ + + Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH------WSYLLLIPMITIITVPF 184 Query: 206 RRLLPDTPSAGRVRLRDLDPLGVLLLGTGVLALLLPFVQSQQWPGNLKWLLLVAAVTLLA 265 L R++ D G++L+ G++ +L F S L+ +V Sbjct: 185 LMKLL--KKEVRIK-GHFDIKGIILMSVGIVFFML-FTTSY------SISFLIVSVLSFL 234 Query: 266 AFVGWESRCGRRGTRPVVDLSLFRVRSYWLGCLLSLLYFAGFTSIFFITTLYLQSGLHYT 325 FV + R+ T P VD L + + +G L + F + ++ + Sbjct: 235 IFV----KHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLS 290 Query: 326 ALQAGLAITPFAVGAALTASP-GGRLVGRFGRPLVLTGLSTVAVGLAATALAAHLVPGRG 384 + G I + + GG LV R G VL T L+ + L A + Sbjct: 291 TAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTF---LSVSFLTASFLL-ET 346 Query: 385 AGWAMVAPLLLAGVGSGLVVAPNQTLTLSQVPVAGAGSAGGTLQTGQRVGSAIGIAAVGS 444 W M ++ G T+ S + AG+ L + GIA VG Sbjct: 347 TSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 445 M 445 + Sbjct: 407 L 407
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 32.5 bits (74), Expect = 0.004 Identities = 42/209 (20%), Positives = 64/209 (30%), Gaps = 28/209 (13%) Query: 248 IGTFGSFIGFGFAFGQVLQV----QFHAQFDTPVKAACLTFLGPLLGSLSRPLGGLLADR 303 IG I FG G V V + Q T + + F G + + +GG+L DR Sbjct: 260 IGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDR 319 Query: 304 FGGARVTFWTFAAMA---LGAGVVLEASRQHSLALFLCGFVALFVLSGAGNGSTYKMIPA 360 G V ++ L A +LE + V + ++ Sbjct: 320 RGPLYVLNIGVTFLSVSFLTASFLLETTSW----FMTIIIVFVLGGLSFTKTVISTIVS- 374 Query: 361 IFRARARAEIAGGTSPAEAEQRSRRRTTALIGVAGAIGAFGGVLVNLAFRQSFLETHNGQ 420 + + E G S T+ + I GG+L Q L Q Sbjct: 375 --SSLKQQEAGAGMSLLN--------FTSFLSEGTGIAIVGGLLSIPLLDQRLLPMEVDQ 424 Query: 421 AAYL------AFLGYYGLCLVVTWAFYLR 443 + YL F G + +VT Y Sbjct: 425 STYLYSNLLLLFSGIIVISWLVTLNVYKH 453
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 28.7 bits (63), Expect = 0.047 Identities = 21/61 (34%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 102 PVLPPLRGLHAPDGLKAGVHAFRTLADCARLAEGAAGAERAVVIGGGVLGVSAARALAAL 161 PV PP+ G + G+H+ + A A+GAA A A I GV V+ AL Sbjct: 52 PVRPPVPGAGGLNASAKGIHSI-AIGATAEAAKGAAVAVGAGSIATGVNSVAIGPLSKAL 110 Query: 162 G 162 G Sbjct: 111 G 111
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 97.2 bits (242), Expect = 3e-25 Identities = 62/343 (18%), Positives = 119/343 (34%), Gaps = 57/343 (16%) Query: 22 RIFVAGHRGLVGSAVVRRLIAAGHEVI-------------TRDRDHL-----------DL 57 + V G G +G V +RL+ AGH+V+ + R L DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 58 RDAARTEAFLREVRPDAVVLAAAKVGGIMANNTYPVQFLEDNLRIQLSVIAGAHAAGAER 117 D + V ++ + + + P + + NL L+++ G + Sbjct: 62 ADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 118 LLFLGSSCIYPKRAPQPIPESSLLTGPLEPTNEAYALAKIAGIVQTQSYRRQFGASYISA 177 LL+ SS +Y P + P+ YA K A + +Y +G Sbjct: 121 LLYASSSSVYGLNRKMPFSTDDSVDHPVSL----YAATKKANELMAHTYSHLYGLPATGL 176 Query: 178 MPTNLYGPGDNFDLETSHVLPALIRRFHEAGRDGSPVVTLWGSGSPRREFLHVDDLAAAC 237 +YGP D+ + +F +A +G + ++ G +R+F ++DD+A A Sbjct: 177 RFFTVYGPWGRPDMA--------LFKFTKAMLEGKSID-VYNYGKMKRDFTYIDDIAEAI 227 Query: 238 LLLLERYDGDEP------------------VNVGCGEDLTIHELANIVGDVTEYQGCVEW 279 + L + + N+G + + + + D + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 280 DTSKPDGTPRKLLDVSRL-TSLGFAPQIPLRDGIARTYAWWLE 321 +P D L +GF P+ ++DG+ W+ + Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRD 330
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 100 bits (250), Expect = 3e-26 Identities = 71/328 (21%), Positives = 119/328 (36%), Gaps = 34/328 (10%) Query: 6 LITGVTGQDGSYLSELLLEKGYTVHGLIRRSSSFNTERIDHIYQGPEEENRSFVLHHADL 65 L+TG G G ++S+ LLE G+ V G+ + ++ + + F DL Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFH--KIDL 61 Query: 66 ADGVALVNLLRDIRPDEVYNLGAQSHVRVSFDAPLYTGDITGLGTIRLLEAVRASGIDTR 125 AD + +L + V+ + VR S + P D G + +LE R + I Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 126 IYQASSSEMFGATPPPQNEKTPF-------HPRSPYSVAKVYSYWATVNYREAYGMFAVN 178 +Y ASSS ++G N K PF HP S Y+ K + Y YG+ A Sbjct: 122 LY-ASSSSVYGL-----NRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATG 175 Query: 179 GILFNHESPRRGETFVTRKITRGVARIRAGLQTHLHLGNLDAVRDWGYAPEYVDAMWRML 238 F P K T+ + G ++ RD+ Y + +A+ R+ Sbjct: 176 LRFFTVYGPWGRPDMALFKFTK---AMLEGKSIDVY-NYGKMKRDFTYIDDIAEAIIRLQ 231 Query: 239 QCDNPDDYVVATGEGVSVRQFLEYAFAHAG-------LDW----REHVRYDAKYE----R 283 D G Y + G +D+ + + +AK + Sbjct: 232 DVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPLQ 291 Query: 284 PSEVDALIGDAAKAEELLGWKPAVKSRE 311 P +V D E++G+ P ++ Sbjct: 292 PGDVLETSADTKALYEVIGFTPETTVKD 319
>SURFACELAYER#Lactobacillus surface layer protein signature. Length = 439 Score = 31.2 bits (70), Expect = 0.017 Identities = 40/196 (20%), Positives = 64/196 (32%), Gaps = 27/196 (13%) Query: 16 ARAAAAALCLLAGALTAAASGGSPAAAL------TPPVSLTADDLTTWQTNGIVWSMAAS 69 A AA A+ + A A S + TP +S A + I S+ S Sbjct: 19 APIAATAMPVNAATTINADSAINANTNAKYDVDVTPSISAIAAVAKSDTMPAIPGSLTGS 78 Query: 70 -----------------DAGVVYTGGTFSTVRPPDAAAGTSEQPAVNFAAFDAATGAPTG 112 T +TV+P + A + V +F+ + G Sbjct: 79 ISASYNGKSYTANLPKDSGNATITDSNNNTVKPAELEADKAYTVTVPDVSFNFGS-ENAG 137 Query: 113 CSLSFTLSSGTATVRALALSPDQKTLYVG-GQFGAVSG--VGVSNIAAIDTATCTPRQGF 169 ++ ++ T T+ V Q G V + N+ AIDT + + Sbjct: 138 KEITIGSANPNVTFTEKTGDQPASTVKVTLDQDGVAKLSSVQIKNVYAIDTTYNSNVNFY 197 Query: 170 KVSVSATVRALAVTAD 185 V+ ATV AV+ D Sbjct: 198 DVTTGATVTTGAVSID 213
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 32.6 bits (74), Expect = 0.001 Identities = 23/73 (31%), Positives = 32/73 (43%), Gaps = 16/73 (21%) Query: 129 VTGEIADAKPAVEHLCTQHEELVREASQGYADGTYKDEQIRPGRYHDVTPTKNCTWQITG 188 +TG A A P +L Q ++LV E +Q V+ T+ IT Sbjct: 185 LTGVGAGASP--NNLLDQRDQLVSELNQ-IVGVE-------------VSVQDGGTYNITM 228 Query: 189 ANGKNLVSGSSAS 201 ANG +LV GS+A Sbjct: 229 ANGYSLVQGSTAR 241
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 35.9 bits (82), Expect = 3e-04 Identities = 50/220 (22%), Positives = 92/220 (41%), Gaps = 33/220 (15%) Query: 61 LSHPHLVAVFDFGAWEDRFYLVMELVEGRSLGDLLRAEERLGAEQVARIAGQAAAGLAA- 119 L++ H +AV +G ++ L+M+ V+G D LR + + +I +A G Sbjct: 193 LANVHGMAVVPYGNRKEE-ALLMDEVDGWRCSDTLRT--LADSWKQGKINSEAYWGTIKF 249 Query: 120 -AHR----------QGIVHRDIKPGNLMLD-AEGSVKIGDFGIAQFVDDPSAALTTTGQI 167 AHR G+VH DIKPGN++ D A G + D G+ + T + Sbjct: 250 IAHRLLDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTES--- 306 Query: 168 VGTSLYLAPERALGRT-AGAASDMYSLGCVIYQLLLG---EPPFRSDTA----TATLYQH 219 + APE +G A SD++ + + + G P + + T+ Sbjct: 307 -----FKAPELGVGNLGASEKSDVFLVVSTLLHCIEGFEKNPEIKPNQGLRFITSEPAHV 361 Query: 220 VDTAPVPLRQRGV-DLSPAFDSYLLGLLAKQPEDRPSAQQ 258 +D P+ + G+ + A+ ++ +L + RP + + Sbjct: 362 MDENGYPIHRPGIAGVETAYTRFITDILGVSADSRPDSNE 401
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 142 bits (360), Expect = 1e-37 Identities = 117/473 (24%), Positives = 193/473 (40%), Gaps = 58/473 (12%) Query: 71 GMYSVAYQRTYRGLPVVGGDAVVVADSEG--RVRGTQSAVSRRINVPTTPTVSAKSAETT 128 G + +++ +G V + + GT + + T +S + AE Sbjct: 87 GHTVMRFEQAIAASLCMGAVLVAHVNDGELSSLSGTLIPNLDKRTLKTEAAISIQQAEMI 146 Query: 129 SRKKLT--------TVTRVDSHRLVVRATGKTSRLAWETVLTGRSAKSPSRLHVFVDAGT 180 +++ + RLV+ +T RLA+E + P +DA Sbjct: 147 AKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNVR-FLTPVPGNWIYMIDAAD 205 Query: 181 GKVLDSYDDVR---------------AGTGNSQWNGPSPLSIDTTASGGSYSLRDPNR-P 224 GKVL+ ++ + G G ++ ++ G Y L+D R Sbjct: 206 GKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQKYINTTYSSYYGYYYLQDNTRGS 265 Query: 225 GLSCADYSTGSVFSKSSDSWGTGNASSKETGCA-DVMWAAQHEWNMLRDWLGRNGHDGNG 283 G+ D +V S + G + A D + A ++ ++ GR +DG+ Sbjct: 266 GIFTYDGRNRTVLPGSLWADGDNQFFASYDAAAVDAHYYAGVVYDYYKNVHGRLSYDGSN 325 Query: 284 RSWPVKV--GLNDVNAYWDGSSVSIGHNNANQWI---GAMDVVGHEFGHGIDQYTPG-GA 337 + V G NA+W+GS + G + ++ G +DVVGHE H + YT G Sbjct: 326 AAIRSTVHYGRGYNNAFWNGSQMVYGDGDGQTFLPFSGGIDVVGHELTHAVTDYTAGLVY 385 Query: 338 NNESG-LGEATGDIMGALTEAYTNEPAPYDDPDYTVGEKINLVG--NGPIRIMYNPSQTG 394 NESG + EA DI G L E Y N +PD+ +GE I G +R M +P++ G Sbjct: 386 QNESGAINEAMSDIFGTLVEFYAN-----RNPDWEIGEDIYTPGVAGDALRSMSDPAKYG 440 Query: 395 DPNCYSSSIPNTEE----HAAAGPLNHWFYLLAEGSNPGGGKPSSPTCNSSSVTGVGIQS 450 DP+ YS T++ H +G +N YLL++G SVTG+G Sbjct: 441 DPDHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQGG----------VHYGVSVTGIGRDK 490 Query: 451 AGKVFYGGMLLK-TSGMTYKRYRTTTLTAARNL-DSGCVLFDRTKAAWDAIGV 501 GK+FY ++ T + + R + AA +L S + K A++A+GV Sbjct: 491 MGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVKQAFNAVGV 543
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 2e-06 Identities = 16/82 (19%), Positives = 32/82 (39%), Gaps = 12/82 (14%) Query: 292 VTNAAKH-----SRATRISVSVKGDGSGVSVSVRDNGTGGADPM----GSGLSGLRSRVD 342 V N KH + +I + D V++ V + G+ G+GL +R R+ Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQ 323 Query: 343 AL---DGRLYIDSPSGGPTTII 361 L + ++ + G ++ Sbjct: 324 MLYGTEAQIKLSEKQGKVNAMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 51.0 bits (122), Expect = 8e-10 Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 4/95 (4%) Query: 2 LAEDSTLLREGLVRLLAEEGHEVLAAVGDGTALVRAVEADPPDLVVVDIRMPPTHTDEGL 61 +A+D +R L + L+ G++V + L R + A DLVV D+ MP + Sbjct: 8 VADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN---AF 63 Query: 62 RAALEIRERWPLVGVLVLSQHVERNYAVRLLSANA 96 I++ P + VLV+S A++ A Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGA 98
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 41.2 bits (96), Expect = 1e-06 Identities = 11/65 (16%), Positives = 26/65 (40%) Query: 3 TRTTGTSRADLIADAALALLAERGMRGLTHRAVDERAGLPQGSTSNYARTRQSLLEVTVQ 62 T+ I D AL L +++G+ + + + AG+ +G+ + + + L + Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 63 RLAER 67 Sbjct: 65 LSESN 69
>PF07520#Virulence protein SrfB Length = 1041 Score = 30.3 bits (68), Expect = 0.023 Identities = 10/30 (33%), Positives = 13/30 (43%) Query: 322 LYSMVPKGIAGHTTSFFDAYGDPDKDKAKR 351 LYS + + G +F D G P D A Sbjct: 561 LYSELTQKFDGRIDTFLDLKGQPRPDPAGG 590
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (260), Expect = 4e-29 Identities = 71/250 (28%), Positives = 98/250 (39%), Gaps = 14/250 (5%) Query: 7 GKVALITGASRGIGYGIAEALVARGDRVCITGRGEDALKEAVEQLGSDRVIGVAGKA--H 64 GK+A ITGA++GIG +A L ++G + + L++ V L ++ A A Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 65 DEAHRAAAVERTMEAFGRVDFLINNAGTNPVFGPIAELDLNVARKVFETNVISALGFAQL 124 D A R G +D L+N AG G I L F N ++ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 125 TWKAWQKENGGAIVNIASVAGISASPFVGAYGMSKAAMVNLTLQLAHEFAPV-VRVNAIA 183 K G+IV + S + AY SKAA V T L E A +R N ++ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 184 PAVVKTKFAKALYEGREAEAAA----------AYPLGRLGVPEDIGGAAAFLTSSQSDWI 233 P +T +L+ PL +L P DI A FL S Q+ I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 234 TGQTLVVDGG 243 T L VDGG Sbjct: 247 TMHNLCVDGG 256
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 128 bits (322), Expect = 4e-38 Identities = 90/254 (35%), Positives = 140/254 (55%), Gaps = 12/254 (4%) Query: 5 EQRVAIVTGAARGIGAATAVRLAAEGRAVAVLDLDEAACKDTVEKITAAGGTALAVGCDV 64 E ++A +TGAA+GIG A A LA++G +A +D + + V + A A A DV Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 65 SDSAQVEAAVARVAAEIGAPTILVNNAGVLRDNLLFKMSESDWDTVMNVHLKGAFLMAKA 124 DSA ++ AR+ E+G ILVN AGVLR L+ +S+ +W+ +V+ G F +++ Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 125 VQKHMVDAKFGRIVSLSSSSALGNR-GQANYSAVKAGLQGFTKTLAKELGKFGITANAVA 183 V K+M+D + G IV++ S+ A R A Y++ KA FTK L EL ++ I N V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 184 PGFIVTEMTAQ------TAARVGMGF-EEFQAAAATQIPVQRVGRPEDIANAIAFFTGDE 236 PG T+M A +V G E F+ T IP++++ +P DIA+A+ F + Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFK----TGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 237 AGFVSGQVMYVAGG 250 AG ++ + V GG Sbjct: 243 AGHITMHNLCVDGG 256
>STREPKINASE#Streptococcus streptokinase protein signature. Length = 440 Score = 30.1 bits (67), Expect = 0.016 Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 338 TIDAVQVLGGYGYTLDFP-VERLMREAKVLQIVEGTNQ 374 T+++VQ + G + LD P V V VEGTNQ Sbjct: 20 TVNSVQAIAGPEWLLDRPSVNNSQLVVSVAGTVEGTNQ 57
>PF06776#Invasion associated locus B Length = 214 Score = 29.9 bits (67), Expect = 0.013 Identities = 11/65 (16%), Positives = 19/65 (29%), Gaps = 1/65 (1%) Query: 7 PRARLRALAAAACTVALGATLLGAAGTASAGAALTATQAAAPAAAVAAPTAADDKVVGYF 66 P + + A + L + A A L A A + + A V Sbjct: 22 PALKAIQMGPAELSPMLASCRRLARRN-GARLMLAGAMAIALSFGWSDRADAQGAVRSVH 80 Query: 67 TNWGV 71 +W + Sbjct: 81 GDWQI 85
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 135 bits (342), Expect = 8e-41 Identities = 84/268 (31%), Positives = 127/268 (47%), Gaps = 17/268 (6%) Query: 12 VSAQLLRGQKALVTGANSGIGMATAIALGRAGADVVVNYVAGADEAEKVVAQIKDFGVRA 71 ++A+ + G+ A +TGA GIG A A L GA + ++ EKVV+ +K A Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAA-VDYNPEKLEKVVSSLKAEARHA 59 Query: 72 YAHEADVSDEAQVVAMVARMVEAFGTIDIMVANAGLQRDAAATEMTLAQWQKVIDVNLTG 131 A ADV D A + + AR+ G IDI+V AG+ R ++ +W+ VN TG Sbjct: 60 EAFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTG 119 Query: 132 QFLCAREAAKEFLRRGVVEEVSRAAGKIICMSSVHQIIPWSGHVNYASSKGGVAMLMQTL 191 F +R +K + R +G I+ + S +P + YASSK M + L Sbjct: 120 VFNASRSVSKYMMD--------RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171 Query: 192 AQELAPQRIRVNAVAPGAIRTPINRDAWSSPEAEADLLR--------LIPYRRVGDPEDI 243 ELA IR N V+PG+ T + W+ +++ IP +++ P DI Sbjct: 172 GLELAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDI 231 Query: 244 ANAVVALASDLLDYVVGATLYVDGGMTL 271 A+AV+ L S ++ L VDGG TL Sbjct: 232 ADAVLFLVSGQAGHITMHNLCVDGGATL 259
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 31.5 bits (71), Expect = 0.012 Identities = 16/60 (26%), Positives = 23/60 (38%), Gaps = 7/60 (11%) Query: 325 ELPEEILDHFEGYRGSFPVRIGNGAADQLQLDIYGEAVYAVAQGGEIAQQTTYQGWRALA 384 + EE+ D F+GY I N +Q+ L+ QG QQ A+A Sbjct: 309 DTLEELRDSFDGY-------INNAFVNQIHLNFVMPPQAQQQQGQGQQQQAQATAQEAVA 361
>FIMBRILLIN#Porphyromonas gingivalis: fimbrillin protein signature. Length = 348 Score = 29.2 bits (65), Expect = 0.011 Identities = 12/39 (30%), Positives = 17/39 (43%) Query: 83 AHYEPYDWTARTFAAPRSLEPAPVVLIEGVGAGRRALRP 121 A+Y DW R + P + P ++E A LRP Sbjct: 198 ANYTHVDWLGRDYTEPSNNAPQGFYVLESTYAQNAGLRP 236
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 31.4 bits (71), Expect = 0.006 Identities = 12/41 (29%), Positives = 18/41 (43%) Query: 22 RGVDAYTMGAYPQAEEEFRAAVRIDPGMADGWLGLHALRAD 62 + Y G Y A + F+A +D + +LGL A R Sbjct: 42 LAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQA 82
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 31.9 bits (72), Expect = 0.003 Identities = 23/99 (23%), Positives = 39/99 (39%), Gaps = 5/99 (5%) Query: 133 DVPAVPKGEVTVTGRLKADETTSASGIKDISDLPDRQVMLINSAQEAERLSRPVLGGYIE 192 D+P +P+ + D+ +A+ I + + M+ + + PVL I Sbjct: 154 DIPNIPQAQRQAAQPPLNDQKRAAARIAWLKNCAGIDYMVKDPNNPGHMMVNPVLLN-IP 212 Query: 193 QTAPEPVGGSPELIEAPDDSSIGPHMAYAVQWWLFAAGV 231 Q P PVG P+ P + +I H QW G+ Sbjct: 213 QGNPNPVGQPPQRANQPANFAIHNHE----QWRSLVVGL 247
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.3 bits (239), Expect = 5e-26 Identities = 65/257 (25%), Positives = 101/257 (39%), Gaps = 11/257 (4%) Query: 4 GLKDRVYIVTGASRGLGNATARALAEDGARVI---ITGRDEKSVEAAAAELGPDAVGLVA 60 G++ ++ +TGA++G+G A AR LA GA + + V ++ A A Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 61 DNADPASAQRLVDSAHERFGRLDGILISVGGPAPGFVADNTDEQWQSAFESVFLGAVRLA 120 D D A+ + G +D ++ G PG + +DE+W++ F G + Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 121 RAAAATL--GEGGVIGFVLSGSVYEPIAGLTISNGLRPGLAGFAKSLADELGPRGIRVVG 178 R+ + + G I V S P + + F K L EL IR Sbjct: 125 RSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 179 VLPGRISTDRMRELDARSGDAEASRTTNEA-----GIPLRRYGTPEEFGRTAAFLLSPAA 233 V PG TD L A + GIPL++ P + FL+S A Sbjct: 185 VSPGSTETDMQWSLWA-DENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 234 SYLTGVMLPVDGGSRHG 250 ++T L VDGG+ G Sbjct: 244 GHITMHNLCVDGGATLG 260
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 27.2 bits (60), Expect = 0.045 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 8/58 (13%) Query: 108 RGRALEGVLADEAGTLDGVARAQV--------VLTGRRSSPRARIRLLMEPHAAPDEA 157 RALEG LA TL V A+V + + SP A + + +EP A DE Sbjct: 131 YQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEG 188
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 24.8 bits (54), Expect = 0.024 Identities = 17/39 (43%), Positives = 19/39 (48%), Gaps = 1/39 (2%) Query: 6 AGMVAGMALG-FAGYFGGFGAFLLVAALGAIGFVVGRFL 43 GMVAG LG G F F AAL + F+ G FL Sbjct: 142 FGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFL 180
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 27.1 bits (60), Expect = 0.023 Identities = 30/141 (21%), Positives = 57/141 (40%), Gaps = 22/141 (15%) Query: 6 EVLEFLNEQLTAELTAINQYFLHAKMQDNFGWTKLAKYTRS--ESFDEM-----KHAEIL 58 V LN QL N + L++K+ F W + + E F+E+ + + + Sbjct: 12 LVENSLNTQL------SNWFLLYSKLH-RFHWYVKGPHFFTLHEKFEELYDHAAETVDTI 64 Query: 59 TDRILFLDGLPNY---QRLFHVRV-----GQTVTEMFQADRQVEVEAIDRLKRGIELMRG 110 +R+L + G P + H + + +EM QA + K I L Sbjct: 65 AERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEE 124 Query: 111 KGDITSANIFESILEDEEQHI 131 D +A++F ++E+ E+ + Sbjct: 125 NQDNATADLFVGLIEEVEKQV 145
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 31.8 bits (72), Expect = 0.004 Identities = 18/76 (23%), Positives = 31/76 (40%), Gaps = 19/76 (25%) Query: 139 GFDTAVGIATEAIDRLHTTAESHMRVLVVEVMGRHAGWIALHSGLAGGANVILIPEQRFD 198 D V I E+ D L + + L++E+MGRH +N+ LI ++ Sbjct: 95 NQDRIVVIDFESTDEL---GFNSIYSLIIEIMGRH-------------SNMTLIRKRDNI 138 Query: 199 IGQVCAWVT---SRFR 211 I +T + +R Sbjct: 139 IMDSIKHITPDINTYR 154
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 74.9 bits (184), Expect = 9e-18 Identities = 29/114 (25%), Positives = 49/114 (42%), Gaps = 1/114 (0%) Query: 14 IRVMVVDDHPMWRDAVARDLSESGFEVVATAGDGPQAVRRAKAVTPDVLVLDLNLPGMPG 73 ++V DD R + + LS +G++V + R A D++V D+ +P Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVR-ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 74 VQVCKELVGSHPGLRVLVLSASGEHADVLEAVKSGATGYLLKSASTQELTEAVR 127 + + + P L VLV+SA ++A + GA YL K EL + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.4 bits (66), Expect = 0.028 Identities = 17/101 (16%), Positives = 35/101 (34%), Gaps = 4/101 (3%) Query: 161 IAIGYVVEVARASERTLARALEIEAATRERERLARDIHDSVLQVLAMVQRRGTALGGEAA 220 +AI + I + E E+L + S ++ A+ + ++G + A Sbjct: 14 VAIAKAFIHLEPNVD--IEKTSITDVSTEIEKLTAALEKSKEELRAIKDQTEASMGADKA 71 Query: 221 ELGRMAGEQEVALRTLVSSGLVPTTRVSEDAAEGAVVRSVE 261 E+ A V + G+ + AE A+ + Sbjct: 72 EI--FAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSD 110
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.040 Identities = 19/118 (16%), Positives = 37/118 (31%), Gaps = 5/118 (4%) Query: 237 FGWQGRVELHYGSMEFLGPHVPLVSTLALGLSVVAFGWLLVWRLRACDFRVNTPADAAFT 296 GW +G G P + ++ +++ G +L R+ R Sbjct: 18 IGWGVYTLTGFGFASLYGS--PKLHSMIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQ 75 Query: 297 AVLLFTTTSRVISPQYMLWLVGLAAVCLVFRDSRMGLPAVLVLLATGVTQLEFPLGFV 354 +L VI M+W V ++ + A + LA + + F+ Sbjct: 76 IILRVLPACVVIG---MVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFM 130
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 34.7 bits (79), Expect = 5e-04 Identities = 28/180 (15%), Positives = 55/180 (30%), Gaps = 11/180 (6%) Query: 22 SAAAATAAATLGAATANADPQDAPRTAKARVDRLYSEAERATEQYNKAGENADRLRGELK 81 +A+ A A LGA + + +++ E+ E+ +K + L+ + Sbjct: 19 TASVAVALTVLGAGLVVNTNEVSAVATRSQT----DTLEKVQERADKFEIENNTLKLKNS 74 Query: 82 RTQDRAARDQERLNRMRTALGSAVSAQYRSGGLDPSLALLLSSDPDTYLDRAATLDRLTE 141 ++ + L +S + +S R A L++ E Sbjct: 75 DLSFNNKALKDHND----ELTEELSNAKEKLRKNDKSLSEKASKIQELEARKADLEKALE 130 Query: 142 HRATELRQLQQAQRSLAQTRAEAARALADLERNRAAVTRHKR---TVERKLARAKQLLDA 198 ++L +A A ADLE+ + L K L+A Sbjct: 131 GAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEA 190
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 37.7 bits (87), Expect = 5e-05 Identities = 34/192 (17%), Positives = 70/192 (36%), Gaps = 5/192 (2%) Query: 31 QAAHADPKPSKGEVKAEVEKLGHEAGEANEQYYGAKEKQQKLEKEVGALQDKVARGQQEI 90 A + K + A L A K + LE E AL+ + A ++ + Sbjct: 140 SAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKAL 199 Query: 91 NTLRNGLGSLAAAQYRSGGIDPSVQLFLSS---NPDSFLDEASALDQLTAKQTETLEKIQ 147 N + +A ++ + + ++ ++A ++ Sbjct: 200 EGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALE 259 Query: 148 EKQRVLAQERKEAQDKLGDLADVRKTLGAKKKKLQDKLAEAQRLLNTMTEAERTKMRKDE 207 +Q L + + A + + KTL A+K L+ + A+ + + + A R +R+D Sbjct: 260 ARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAEKADLEH-QSQVLNANRQSLRRDL 318 Query: 208 QRASRSASDRVE 219 ASR A ++E Sbjct: 319 D-ASREAKKQLE 329 Score = 35.0 bits (80), Expect = 4e-04 Identities = 29/182 (15%), Positives = 60/182 (32%), Gaps = 3/182 (1%) Query: 43 EVKAEVEKLGHEAGEANEQYYGAKEKQQKLEKEVGALQDKVARGQQEINTLRNGLGSLAA 102 E++A L A K + LE E AL + A ++ + N + +A Sbjct: 117 ELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSA 176 Query: 103 AQYRSGGIDPSVQLFLSSNPDSFLDEASALDQLTAKQT---ETLEKIQEKQRVLAQERKE 159 +++ + + + +AK + ++ L + + Sbjct: 177 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEG 236 Query: 160 AQDKLGDLADVRKTLGAKKKKLQDKLAEAQRLLNTMTEAERTKMRKDEQRASRSASDRVE 219 A + + KTL A+K L+ + AE ++ L K + + A+ E Sbjct: 237 AMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEAE 296 Query: 220 LG 221 Sbjct: 297 KA 298 Score = 32.0 bits (72), Expect = 0.004 Identities = 30/200 (15%), Positives = 63/200 (31%), Gaps = 17/200 (8%) Query: 30 SQAAHADPKPSKGEVKAEVEKLGHEAGEANEQYYGAKEKQQKLEKEVGALQDKVARGQQE 89 +A A+ + + + + ++ LEK + + + Sbjct: 188 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAK 247 Query: 90 INTLRNGLGSLAAAQYRSGGIDPSVQLFLSSNPDSFLDEASALDQLTAKQTETLEKIQEK 149 I TL +L A Q F + + L+ A ++ + Sbjct: 248 IKTLEAEKAALEARQAELEKALEGAMNFS----TADSAKIKTLEAEKAALEAEKADLEHQ 303 Query: 150 QRVLAQERKEAQDKLGDLADVRKTLGAKKKKLQDKLA-------------EAQRLLNTMT 196 +VL R+ + L + +K L A+ +KL+++ +A R Sbjct: 304 SQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQL 363 Query: 197 EAERTKMRKDEQRASRSASD 216 EAE K+ + + + S Sbjct: 364 EAEHQKLEEQNKISEASRQS 383
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 38.1 bits (88), Expect = 7e-05 Identities = 30/123 (24%), Positives = 54/123 (43%), Gaps = 10/123 (8%) Query: 140 QRADAERADEESRRELERLRDELAQARSQTKS---ETERLRGELDAARKEADSLQRKLRS 196 + E L E A Q++ + LR +LDA+R+ L+ + + Sbjct: 275 FSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQK 334 Query: 197 VANEVKRGEAALRRSRAETDAVRSEAAAQVSAAESESRRLKARLGEAEASVEAGRR---A 253 + + K EA+ + R + DA R E+E ++L+ + +EAS ++ RR A Sbjct: 335 LEEQNKISEASRQSLRRDLDASREAKK----QLEAEHQKLEEQNKISEASRQSLRRDLDA 390 Query: 254 ARE 256 +RE Sbjct: 391 SRE 393 Score = 32.7 bits (74), Expect = 0.003 Identities = 34/122 (27%), Positives = 55/122 (45%), Gaps = 4/122 (3%) Query: 138 EVQRADAERADEESRRELERLRDELAQARSQTK-SETER--LRGELDAARKEADSLQRKL 194 R R + SR ++L E + Q K SE R LR +LDA+R+ L+ + Sbjct: 308 NANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEH 367 Query: 195 RSVANEVKRGEAALRRSRAETDAVRSEAAAQVSAAESESRRLKARLGEAEASVEAGRRAA 254 + + + K EA+ + R + DA R EA QV A E+ A L + +E ++ Sbjct: 368 QKLEEQNKISEASRQSLRRDLDASR-EAKKQVEKALEEANSKLAALEKLNKELEESKKLT 426 Query: 255 RE 256 + Sbjct: 427 EK 428 Score = 32.3 bits (73), Expect = 0.004 Identities = 23/116 (19%), Positives = 51/116 (43%), Gaps = 3/116 (2%) Query: 137 EEVQRADAERADEESRRELERLRDELAQARSQTKSETERLRGELDAARKEADSLQRKLRS 196 E+ + +R+ L R D +A+ Q ++E ++L + + SL+R L + Sbjct: 296 EKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 355 Query: 197 VANEVKRGEAALRRSRAE---TDAVRSEAAAQVSAAESESRRLKARLGEAEASVEA 249 K+ EA ++ + ++A R + A+ ++++ L EA + + A Sbjct: 356 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAA 411
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 606 bits (1563), Expect = 0.0 Identities = 231/1043 (22%), Positives = 442/1043 (42%), Gaps = 50/1043 (4%) Query: 4 LSRFSLAQRALIGLISIVALVFGAIAIPQLKQQLLPTIELPMVSVLAPYQGASPDVVEKQ 63 ++ F + + +++I+ ++ GA+AI QL PTI P VSV A Y GA V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 64 VVEPLENSIKAVDGVTGTTSTA-SEGNAVIMASFDFGSEGTKQLVADIQQAVNRARAQLP 122 V + +E ++ +D + +ST+ S G+ I +F G++ V +Q + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQV-QVQNKLQLATPLLP 119 Query: 123 DDV-DPQVIAGSTDDIPAVVLAVTSDK---DQQALADQLDRTVVPALEDISGVGQVTVDG 178 +V + + +V SD Q ++D + V L ++GVG V + G Sbjct: 120 QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 179 VQDLQVSITPDDKKLAGAGLNAGTLSQALQAGGATVPAGSF------SESGKSRTVQVGG 232 + I D L L + L+ + AG + ++ Sbjct: 180 -AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 233 AFTSLKQIEDLRVTGQDPATGKPGEPVRVGDVATVKQEPSTAVSITRTNGKPSLAVMATM 292 F + ++ + + G VR+ DVA V+ I R NGKP+ + + Sbjct: 239 RFKNPEEFGKVTL-----RVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKL 293 Query: 293 DKDGSAVAISDAVKDKLPDLRKDLGASAELTVVSDQGPAVSKAISGLTTEGALGLLFAVI 352 +A+ + A+K KL +L+ ++ D P V +I + ++ + Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 353 VILVFLASLRSTLVTAVSIPLSVVLALIVLWTRDLSLNMLTLGALTIAIGRVVDDSIVVL 412 V+ +FL ++R+TL+ +++P+ ++ +L S+N LT+ + +AIG +VDD+IVV+ Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 413 ENIKRHL-GYGEERQSAIITAVKEVAGAVTSSTLTTVAVFLPIGLVGGMVGELFGSFSLT 471 EN++R + + A ++ ++ GA+ + AVF+P+ GG G ++ FS+T Sbjct: 414 ENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSIT 473 Query: 472 VTAALLASLLVSLTVVPVLSYWFLRAPKGATENPDEARREAEEKEARSRLQKLYVPVLRF 531 + +A+ S+LV+L + P L L+ P A + ++ Y + Sbjct: 474 IVSAMALSVLVALILTPALCATLLK-PVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 532 ATRRRITSIVIAIVVFLATFGMAPLLKTNFFDQGEQEVLSIKQELAPGTSLAAADKAARK 591 ++I ++ + L ++F + +Q V +L G + K + Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 592 VEKVLTEDEGVKDYQVTVGSSGFMAAFGGGTGANQASYQVTLKD----SGDFDATQKRID 647 V ++E V +GF G N V+LK +GD ++ + I Sbjct: 593 VTDYYLKNEKANVESV-FTVNGFSF---SGQAQNAGMAFVSLKPWEERNGDENSAEAVIH 648 Query: 648 TALGKLDGIGDTTIAA---------GDGFGSQDLSVVVKAADADVLKKASEEVRAEVAE- 697 A +L I D + G G + D L +A ++ A+ Sbjct: 649 RAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQH 708 Query: 698 LKDVTDVQSDLAQSVPRISVKAN-AKAADAGFNQATLGAAVAGAVRGTPSGKAIMDDTER 756 + V+ + + + ++ + KA G + + + ++ A+ GT I + Sbjct: 709 PASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVK 768 Query: 757 DVVIKSAHPATTMAE-LKNLSL-----GPVELGRIADVELVPGPVSMTRIDGQRAATITA 810 + +++ + E + L + V V G + R +G + I Sbjct: 769 KLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQG 828 Query: 811 KPT-GDNTGAVSSSLQTKINALKLPDGATATIGGVSEDQNDAFLKLGLAMLAAIAIVFML 869 + G ++G + ++ + KLP G G+S + + + + + +VF+ Sbjct: 829 EAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLC 886 Query: 870 LVATFKSLIQPLILLVSIPFAATGAIGLLVITGTPMGVPAMIGMLMLIGIVVTNAIVLID 929 L A ++S P+ +++ +P G + + V M+G+L IG+ NAI++++ Sbjct: 887 LAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE 946 Query: 930 LINQ-YRAQGMGVVEAVIEGGRHRLRPILMTALATIFALLPMALGVTGEGGFISQPLAVV 988 +G GVVEA + R RLRPILMT+LA I +LP+A+ G G + + Sbjct: 947 FAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAIS-NGAGSGAQNAVGIG 1005 Query: 989 VIGGLVTSTLLTLLLVPTLYAMV 1011 V+GG+V++TLL + VP + ++ Sbjct: 1006 VMGGMVSATLLAIFFVPVFFVVI 1028 Score = 112 bits (282), Expect = 3e-27 Identities = 90/521 (17%), Positives = 185/521 (35%), Gaps = 47/521 (9%) Query: 8 SLAQRALIGLISIVALVFGAIAIPQLKQQLLPTIE--LPMVSVLAPYQGASPDVVEK--- 62 L LI + + + +L LP + + + + P GA+ + +K Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLP-AGATQERTQKVLD 591 Query: 63 QVVEPLENS----IKAVDGVTG-TTSTASEGNAVIMASFDFGSE--GTKQLVADIQQAVN 115 QV + + +++V V G + S ++ + S E G + + Sbjct: 592 QVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAK 651 Query: 116 RARAQLPDDV-----DPQVIAGSTDDIPAVVLAVTSDKDQQALADQLDRTVVPALEDISG 170 ++ D P ++ T L + AL ++ + A + + Sbjct: 652 MELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPAS 711 Query: 171 VGQVTVDGVQD-LQVSITPDDKKLAGAGLNAGTLSQALQAGGATVPAGSFSESGKSRTVQ 229 + V +G++D Q + D +K G++ ++Q + F + G+ + + Sbjct: 712 LVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLY 771 Query: 230 VGGAFTSLKQIEDLRVTGQDPATGKPGEPVRVGDVATVKQEPSTAVSITRTNGKPSLAVM 289 V ED+ + GE V T + + R NG PS+ + Sbjct: 772 VQADAKFRMLPEDV---DKLYVRSANGEMVPFSAFTTSHWVYG-SPRLERYNGLPSMEIQ 827 Query: 290 ATMDKD---GSAVAISDAVKDKLPDLRKDLGASAELTVVSDQGPAVSKAISGLTTEGALG 346 G A+A+ + + KLP G + T +S Q + Sbjct: 828 GEAAPGTSSGDAMALMENLASKLPA-----GIGYDWTGMSYQERL---------SGNQAP 873 Query: 347 LLFAVIVILVFLA------SLRSTLVTAVSIPLSVVLALIVLWTRDLSLNMLTLGALTIA 400 L A+ ++VFL S + + +PL +V L+ + ++ + L Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 401 IGRVVDDSIVVLENIK-RHLGYGEERQSAIITAVKEVAGAVTSSTLTTVAVFLPIGLVGG 459 IG ++I+++E K G+ A + AV+ + ++L + LP+ + G Sbjct: 934 IGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNG 993 Query: 460 MVGELFGSFSLTVTAALLASLLVSLTVVPVLSYWFLRAPKG 500 + + V ++++ L+++ VPV R KG Sbjct: 994 AGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCFKG 1034
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 58.7 bits (142), Expect = 3e-12 Identities = 24/119 (20%), Positives = 49/119 (41%), Gaps = 4/119 (3%) Query: 5 IKVLLVDDQALLRSAFRVLVDSEADMEVVGEAADGAQAVELARSTRADVVLMDIRMPGTD 64 +L+ DD A +R+ + S A +V ++ A + D+V+ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 65 GLTATRMVSADPELADVRVVMLTTFEVDEYVVQSLRAGASGFLGKGAEPEELLNAIRVA 123 + D+ V++++ +++ GA +L K + EL+ I A Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118
>PF06580#Sensor histidine kinase Length = 349 Score = 41.4 bits (97), Expect = 4e-06 Identities = 53/370 (14%), Positives = 106/370 (28%), Gaps = 94/370 (25%) Query: 58 SGVVLMVLGAVVLI----WRRRKPMAVLAATAGLTVVELVRSDPPAPVVMSTVIALYTVA 113 + + ++G V+ + +R+ L + V + VI + Sbjct: 44 FNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRV----------LPACVVIGMVWFV 93 Query: 114 ARTDRPTTWRVGLLTMAALTAAAMSFGAAPWYSQENFGVFAWTGMAGAVGDAVRSRRAFV 173 A T + WR+ A + + F W+ Sbjct: 94 ANT---SIWRLLAFINTKPVAFTLPLALS-IIFNVVVVTFMWSL--------------LY 135 Query: 174 DAIRERAERAERTRDEEARRRVAEERLRIARDLHDVVAHHIALVNVQAGVAAHVMDKRPD 233 + ++ ++ + + ++ L + H + N + A ++ + P Sbjct: 136 FGWH-FFKNYKQAEIDQWKMASMAQEAQLMA-LKAQINPHF-MFNALNNIRALIL-EDPT 191 Query: 234 QAKEALAHVREASRSALNELRATVGLLRQSGDPEAPTEPAPGLAVLDELVDTVR------ 287 +A+E L + S L +R + LR S + L + + V Sbjct: 192 KAREMLTSL-----SEL--MRYS---LRYSNARQVS---------LADELTVVDSYLQLA 232 Query: 288 --RAG--LPVEVACTDRRPPLPAAVDLAAYRV----IQEALTNVRKHA----GPGAKAEV 335 + L E + +V +Q + N KH G K + Sbjct: 233 SIQFEDRLQFENQINP---------AIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILL 283 Query: 336 SVVRVGATAEVTVIDNGSGGGVRNGDGGGHGLLGMRERVTALGGSLTAGPRYG------- 388 + T + V + GS + G GL +RER+ L G Sbjct: 284 KGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLY-----GTEAQIKLSEKQ 338 Query: 389 GGFRVHAILP 398 G ++P Sbjct: 339 GKVNAMVLIP 348
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 57.7 bits (139), Expect = 2e-11 Identities = 39/199 (19%), Positives = 68/199 (34%), Gaps = 36/199 (18%) Query: 58 EYQDVIKNVLPSVVQIE----ASNSLGSGVIYDSKGHIVTNAHVVGNEKTFKVTV----- 108 + D V I+ + SGV+ K ++TN HVV + Sbjct: 78 QITDTTNGHYAPVTYIQVEAPTGTFIASGVVV-GKDTLLTNKHVVDATHGDPHALKAFPS 136 Query: 109 -----ATGEKVLRASLVAAYPEQ-DLAVIKLAGVPAG------LKPAKFGDSEKVEVGQI 156 A + Y + DLA++K + +KPA ++ + +V Q Sbjct: 137 AINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQN 196 Query: 157 VLAMGSPLGLSSSVTQGIVSALGRTVSESSAGGGTGATIANMVQTSAAINPGNSGGALVN 216 + G P V+ + + + + G +Q + GNSG + N Sbjct: 197 ITVTGYPGDKP-------VATMWESKGKITYLKGEA------MQYDLSTTGGNSGSPVFN 243 Query: 217 LNSEVIGIPTLGAIDPQIG 235 +EVIGI G + + Sbjct: 244 EKNEVIGIHW-GGVPNEFN 261
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 109 bits (274), Expect = 5e-31 Identities = 75/256 (29%), Positives = 109/256 (42%), Gaps = 11/256 (4%) Query: 5 EGRRALITGGGSGIGQATVHRVLAEGGRVVAADVNEAGLKATYATAVADG-TADRLTTLV 63 EG+ A ITG GIG+A + ++G + A D N L+ ++ A+ A+ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP--- 63 Query: 64 LDISDEAAVQAGVASAVATLGGLDVLVNAAGILRSEHTHKTSLEFFNKILAVNLTGTFLM 123 D+ D AA+ A +G +D+LVN AG+LR H S E + +VN TG F Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 124 IREAIPALLAGDKPVVVNFSSTSASFAHPYMSAYAASKGGVQSMTHALASEYSKQGLRVV 183 R ++ +V S A M+AYA+SK T L E ++ +R Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 184 AVAPGSISSDM-----TSGNGPGLPADADMSLFMKLSPALGEGFASPDTVAGVVAMLGSQ 238 V+PGS +DM NG + F K L + A P +A V L S Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETF-KTGIPLKK-LAKPSDIADAVLFLVSG 241 Query: 239 DGAFITGTEIRIDGGT 254 IT + +DGG Sbjct: 242 QAGHITMHNLCVDGGA 257
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.6 bits (157), Expect = 6e-15 Identities = 33/183 (18%), Positives = 58/183 (31%), Gaps = 10/183 (5%) Query: 8 PSLTERRKAATQLDIARAAAALFAERGPEGTTAEDIAHRAGVALRTFYRYFRSKQDAVGP 67 T++ T+ I A LF+++G T+ +IA AGV Y +F+ K D Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 68 LLSGGAERWRALLE--AAEPGDALAGVLEQAVTEALRVPGADAAEQLSWTRGLLRAAVED 125 + L A+ VL + + L + +L ++ E Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRL--LMEIIFHKCEF 119 Query: 126 PALRAVWYRVNQDSEERLLPVLTRL------AGDGADPLEVRLAAAAATDAVRVALEAWA 179 AV + ++ + + A L R AA + +E W Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWL 179 Query: 180 ETD 182 Sbjct: 180 FAP 182
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 40.5 bits (95), Expect = 5e-06 Identities = 46/244 (18%), Positives = 72/244 (29%), Gaps = 45/244 (18%) Query: 5 RIAVTGSTGLIGAALVRSLRADGHEVV-----------RLVRHPARAGDEVEWDPKRGYV 53 + VTG+ G IG + + L GH+VV L + + + + + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 54 DGAGLV-------GCDAVVHLAG-AGVGDHRWTEEYKREIRDSRVLGTAAIAEAVASLGV 105 + + V V R++ E DS + G I E + Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAV---RYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 106 PPKVLLCGSAIGYYGDTGDRAIDESAPHGTGFLPSVCVDWEAAAAPAAAAGIRTVYAR-- 163 + S++ YG AA A + Y+ Sbjct: 119 QHLLYASSSSV--YGLNRKMPFSTDDSVDHPVSLY-------AATKKANELMAHTYSHLY 169 Query: 164 ----TGLVVAREGGAWGR----LFPLFRAGLGGR----LGNGRQYWSFIALHDHIAALRH 211 TGL G WGR LF +A L G+ G+ F + D A+ Sbjct: 170 GLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 212 LLDT 215 L D Sbjct: 230 LQDV 233
>cloacin#Cloacin signature. Length = 551 Score = 36.2 bits (83), Expect = 4e-04 Identities = 31/109 (28%), Positives = 37/109 (33%), Gaps = 12/109 (11%) Query: 161 GGAGGARAAGGL--GRSGGASGAAGAPGAAEAGGSARPGGPGGARGIGAQGVHGSHWPGG 218 G GA + G G G GA + P G G GI G G H GG Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG-HGNGG 66 Query: 219 SGHGATGASGVSGRGAVRGPVPSRPSGPPAPPGSPAPSTAPASLGTGLS 267 + G SG G + P G PA ST P + G +S Sbjct: 67 GNGNSGGGSGTGGNLS--------AVAAPVAFGFPALST-PGAGGLAVS 106
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 61.8 bits (150), Expect = 6e-12 Identities = 38/168 (22%), Positives = 77/168 (45%), Gaps = 23/168 (13%) Query: 504 AFITAVTFLLMLFCFRSYVIAVTSILLNLLSVAAAYGVMVAVFQHGWGASLIGSEGVGAI 563 + + L L R+ +I ++ + LL + ++ A +G S+ Sbjct: 348 IMLVFLVMYLFLQNMRATLIPTIAVPVVLL---GTFAILAA-----FGYSI--------- 390 Query: 564 EAWIPLFVLVVLFGLSMDYHVFVVSRI-REARDRGLHTRAAIDEGIRRTAGAVTGAAVIM 622 + +F +V+ GL +D + VV + R + L + A ++ + + GA+ G A+++ Sbjct: 391 -NTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVL 449 Query: 623 VAVF---AVFGTLSMQDMQQMGVGLAVAVLLDATIVRMILLPSVMALL 667 AVF A FG + +Q + + A+ L + +V +IL P++ A L Sbjct: 450 SAVFIPMAFFGGSTGAIYRQFSITIVSAMAL-SVLVALILTPALCATL 496 Score = 52.9 bits (127), Expect = 4e-09 Identities = 48/318 (15%), Positives = 106/318 (33%), Gaps = 30/318 (9%) Query: 75 DVAREVSAAIGRTGEVANLAAPIPSEDGKDALITFDMKGDAATAPDRVQPVLDAVSAVRA 134 DVAR + GE N+ A +GK A A A D + + ++ ++ Sbjct: 264 DVAR-----VELGGENYNVIA---RINGKPAAGLGIKLATGANALDTAKAIKAKLAELQP 315 Query: 135 DHP-DVTIHQFGEASAGKWLGDLLSEDFKKAEFTAVPLALGILLVAFGAVVAALLPVGLA 193 P + + + + L + K F A+ L ++ + + A L+P Sbjct: 316 FFPQGMKVLYPYDTTP---FVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAV 372 Query: 194 LTACMAAFGLLSLASHQLHLFQTTYSVMFLMGFAVG----VDYCLFYLRR-ERDERAAGR 248 + F +L F + + + + G + VD + + ER Sbjct: 373 PVVLLGTFAIL-------AAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKL 425 Query: 249 DAETALRIAAATSGRAVLVSGLTVMVAMAGM-FLSGLM--LFKGFALATIIVVFIAMLGS 305 + A + + A++ + + M F G +++ F++ + + +++L + Sbjct: 426 PPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVA 485 Query: 306 VTVLPALLSWLGDRIDAGRVPFLNRRSSRRGNRRARASGGFAGTVLKPVLARPKIF--AA 363 + + PAL + L + + N S + +L + Sbjct: 486 LILTPALCATL-LKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIY 544 Query: 364 ASVVVLLALAAPALGMKT 381 A +V + + L Sbjct: 545 ALIVAGMVVLFLRLPSSF 562
>PF06580#Sensor histidine kinase Length = 349 Score = 34.5 bits (79), Expect = 8e-04 Identities = 11/70 (15%), Positives = 25/70 (35%), Gaps = 7/70 (10%) Query: 355 RVWVDIHHADAMLRVSVTDNGRGGAAV---GSGSGLSGIERRLGTF---DGIMAVSSPAG 408 ++ + + + + V + G +G+GL + RL + + +S G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 409 GPTMVTMEIP 418 + IP Sbjct: 340 KVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 45.2 bits (107), Expect = 6e-08 Identities = 38/163 (23%), Positives = 67/163 (41%), Gaps = 12/163 (7%) Query: 2 RVVLAEDLFLLRDGLVRLLEAYDFEIAAAVETGPELTRALDELEPDVAVVDVRLPPSHTD 61 +++A+D +R L + L +++ L R + + D+ V DV +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPD---E 60 Query: 62 EGLQCALAARQARPGLPVLVLSQHVEQLYARELLADGNGGIGYLLKDRVFDAEQFIDAVR 121 ++ARP LPVLV+S + A + A G YL K FD + I + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIK--ASEKGAYDYLPKP--FDLTELIGIIG 116 Query: 122 RVAAGGTAMDPQVISQLLSRRSQDKPMGGLTPRELEVMELMAQ 164 R A + S+L P+ G + E+ ++A+ Sbjct: 117 RA----LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 2e-15 Identities = 29/141 (20%), Positives = 55/141 (39%), Gaps = 9/141 (6%) Query: 6 RRRMGVEERRQQLIGVALELFSHRSPDEVSIDEIAAAAGISRPLVYHYFPGKQSLYEAAL 65 + + +E RQ ++ VAL LFS + S+ EIA AAG++R +Y +F K L+ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 66 RRAADELAARFVE---PREGPLGARLLRVMGRFFD--FVEEHGPGF-SALMRGGPAVGSS 119 + + +E G + L ++ + EE + VG Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG-- 121 Query: 120 TANAMIDGVRQAAYEQILAHL 140 A++ ++ + + Sbjct: 122 -EMAVVQQAQRNLCLESYDRI 141
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (262), Expect = 3e-29 Identities = 62/194 (31%), Positives = 87/194 (44%), Gaps = 5/194 (2%) Query: 11 KTAVVTGAGSGIGRAVALALTGAGWSVALAGRRPEPLAETAALAGKNARVI-TVPTDVSR 69 K A +TGA GIG AVA L G +A PE L + + AR P DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 PEDVDALFSSARECFGRLDLLFNNAGAFGPRSVPVEDLSVEDWRSVVDVNVTGAFLCAQA 129 +D + + G +D+L N AG R + LS E+W + VN TG F +++ Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVL--RPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 130 AYRLMKAQDPQGGRIINNGSVSAHAPRPHSVAYTATKHAMTGLTKSLSLDGRPYRIACGQ 189 + M + + G I+ GS A PR AY ++K A TK L L+ Y I C Sbjct: 127 VSKYMMDR--RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 190 IDVGNAATDMTERM 203 + G+ TDM + Sbjct: 185 VSPGSTETDMQWSL 198
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 66.7 bits (163), Expect = 1e-14 Identities = 67/362 (18%), Positives = 108/362 (29%), Gaps = 91/362 (25%) Query: 3 LRILITGATGFIGSHVVAAARA-----------TPGVRLRLMTHRTALTATAGAGPGIET 51 ++ L+TGA GFIG HV + L R L A PG + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ----PGFQF 56 Query: 52 VHGDLADPATLRG--SCEGVDAVIHCASRIG-----GDEPTARSVNDQGTRALAEEAVRC 104 DLAD + + + V R+ + N G + E Sbjct: 57 HKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN 116 Query: 105 GVTRIVHLSTASVYGRG---PFTRLRPGQAEPDPASVTSLTRAAAE------QHVLAAGG 155 + +++ S++SVYG PF+ P S+ + T+ A E H+ Sbjct: 117 KIQHLLYASSSSVYGLNRKMPFSTDDS---VDHPVSLYAATKKANELMAHTYSHLYGLPA 173 Query: 156 VVVRPHIVYGAGDRWAVPGLVALVRQLSAVLTGCEARHSLIDVRTLGR------------ 203 +R VYG W P + AL + A+L G IDV G+ Sbjct: 174 TGLRFFTVYGP---WGRPDM-ALFKFTKAMLEG-----KSIDVYNYGKMKRDFTYIDDIA 224 Query: 204 -ALLGAALSPKEPAG-----------------VYHVNHPEPVSCSQLLSTVVDELRLPWG 245 A++ VY++ + PV + + D L + Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE-- 282 Query: 246 ATGIDVDTARERLADVPFALHHLGMLAVAHWFTD-ERVGQDFDWEPGEGFATAFARHAPW 304 + + DV D + + + + P W Sbjct: 283 ---AKKNMLPLQPGDVL------------ETSADTKALYEVIGFTPETTVKDGVKNFVNW 327 Query: 305 YR 306 YR Sbjct: 328 YR 329
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 87.8 bits (217), Expect = 1e-23 Identities = 40/169 (23%), Positives = 69/169 (40%), Gaps = 16/169 (9%) Query: 4 QARAIQTRRSILVAAAAVFDERGYSSATISEILARAGVTKGALYFHFTSKEDLALGVMD- 62 + A +TR+ IL A +F ++G SS ++ EI AGVT+GA+Y+HF K DL + + Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 63 ---------VQLDSDPLPAQLTKLQELVDQGMLLAHRLRHEPLVRASVGLAMDQA----- 108 ++ + L+ L+E++ + L+ + + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 109 VEGLDRGTPFRAWIDRLEHLLTAAKNQGELLPHVNARETAEMLAGSFSG 157 V+ R DR+E L L + R A ++ G SG Sbjct: 126 VQQAQRNLCLE-SYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 60.2 bits (146), Expect = 6e-13 Identities = 27/131 (20%), Positives = 49/131 (37%), Gaps = 2/131 (1%) Query: 12 RVLLAEDQGMMRGALALLLGLEPDIEVVAQVGAGDEIVAAALLSRPDVALLDIELPGRSG 71 +L+A+D +R L L +V + D+ + D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 72 LDAAADLREEVPDCRVLILTTFGRPGYLRRAMEAGAAGFLVKDGPVEELAAAIRRVLSGE 131 D +++ PD VL+++ +A E GA +L K + EL I R L+ Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 132 TVIDPALAAAA 142 L + Sbjct: 123 KRRPSKLEDDS 133
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 35.0 bits (80), Expect = 0.001 Identities = 36/174 (20%), Positives = 64/174 (36%), Gaps = 25/174 (14%) Query: 15 PSRLVVTVRRAADGGTAGA-GFVLGIDTVLTCAHVVNDALGRPM-LEARPPQLEEILVEV 72 V ++ A GT A G V+G DT+LT HVV+ G P L+A P + Sbjct: 86 HYAPVTYIQVEAPTGTFIASGVVVGKDTLLTNKHVVDATHGDPHALKAFPSA-------I 138 Query: 73 RGTSTE--QYFARLLHWVAPRAKDGSTVR---EGDSEWLGDLAVLRIDGPAGGLPAAPDR 127 + + A + + D + V+ ++ +G++ PA A + Sbjct: 139 NQDNYPNGGFTAEQITKYSGEG-DLAIVKFSPNEQNKHIGEVV-----KPATMSNNAETQ 192 Query: 128 AAMSTDQEVSAWHGGGRAATLARLTVASLHGSHGYLDGEATGMAVGPGYSGGPL 181 + V+ + G AT+ + + G ++ G SG P+ Sbjct: 193 VNQNI--TVTGYPGDKPVATMWE-SKGKITYLKGE--AMQYDLSTTGGNSGSPV 241
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 35.9 bits (82), Expect = 0.001 Identities = 29/109 (26%), Positives = 45/109 (41%), Gaps = 5/109 (4%) Query: 9 RLAEALRVLSACGHDLDADQLLDVLWLARS--LPAGPGAPLHRERPETGQPSAGPG--PE 64 R ++V++ G D + +DV + R P AP + PE P+ P P Sbjct: 284 RNGNPVQVVATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEV-SPAENPANNPA 342 Query: 65 PDRVSLRRPLPEPDDRDLPDLTAPSLYAAARQPPAPQSPLPRHGRDSRK 113 P+ RP PEPD PD + +P +P P +GR ++ Sbjct: 343 PNENPGTRPNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKE 391
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 132 bits (334), Expect = 4e-36 Identities = 85/400 (21%), Positives = 165/400 (41%), Gaps = 16/400 (4%) Query: 26 CVGQFLVVLDVSVVNVALPSMRSDLAMTAAGLQWVLNAYSIAFAGFMLLGGRAADIYGRK 85 C+ F VL+ V+NV+LP + +D A WV A+ + F+ + G+ +D G K Sbjct: 20 CILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIK 79 Query: 86 RMFLIGLGLFTAASLAGGLAQEGWQLL-AARAAQGLGAAVLAPATLTLLTTTVPEGPART 144 R+ L G+ + S+ G + + LL AR QG GAA PA + ++ R Sbjct: 80 RLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIPKENRG 138 Query: 145 KAIGTWMAVGAGGGAAGGLIGGVLTDLLSWRWVLLINVPVGVLVLAGAAVWLAEGRAGDR 204 KA G ++ A G G IGG++ + W + L+ +P+ ++ + L + + Sbjct: 139 KAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSY--LLLIPMITIITVPFLMKLLKKEVRIK 196 Query: 205 RRIDFLGAVLVTAGLAFVAYGIVQTEESGWTAEATLAPLLGGVALLIAFVVVEARTAEPL 264 D G +L++ G+ F T +++ L+ V + FV + +P Sbjct: 197 GHFDIKGIILMSVGIVFFMLF---------TTSYSISFLIVSVLSFLIFVKHIRKVTDPF 247 Query: 265 MPLRVLGARAVTSANAAMFVIGSATFSMWYFMTVYAQTVLGYSPLQAGLALM-PTSLAVV 323 + + +I + + V S + G ++ P +++V+ Sbjct: 248 VDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVI 307 Query: 324 IGSKCAPRVMARAGAKNLALIGTTVAAAGFGWQSTMGADGSYLTSVCLPGVLMMAGAGLA 383 I ++ R G + IG T + F S + S+ ++ + V ++ G Sbjct: 308 IFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIII--VFVLGGLSFT 365 Query: 384 STPLASLAITGAAHGEAGLVSGLVNTSRTMGGALGLAVLS 423 T ++++ + EAG L+N + + G+A++ Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.5 bits (165), Expect = 3e-15 Identities = 37/186 (19%), Positives = 67/186 (36%), Gaps = 11/186 (5%) Query: 2 IRVLIADDEPMIRKGVGSVLSTDPEIDVVAEAADGHDAVELVRRHRPAVAVLDIRMPGMN 61 +L+ADD+ IR + L + DV ++ + + V D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GIEAAAEIRRTVPETGVVMLTTFGEDDYILQALGGGAAGFLIKSGEPEELIAGVRAVADG 121 + I++ P+ V++++ ++A GA +L K + ELI + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA--- 118 Query: 122 AAYLSPKVAARVVAHLSATGAGALAGRRTA---ARERVRALTGRERDVLAFLGSGLSNGQ 178 L+ + L GR A + L + ++ SG Sbjct: 119 ---LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKEL 175 Query: 179 IARRLH 184 +AR LH Sbjct: 176 VARALH 181
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 28.7 bits (64), Expect = 0.038 Identities = 22/107 (20%), Positives = 33/107 (30%), Gaps = 7/107 (6%) Query: 16 LAACVVLGAGAAVVAGLAPGGLGRAGAVEVTGGASASAYRSLTGAVADGPSWTGPLLEAA 75 + A + GAGAA L + R E G A + GP+ G + Sbjct: 107 IMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI 166 Query: 76 TEGTL-------VVLGLLLVWAWWGAVRRGDTRLSAGTVLTGIGTVL 115 L ++ L+ VR G +L +G V Sbjct: 167 HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVF 213
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 41.0 bits (96), Expect = 6e-06 Identities = 42/150 (28%), Positives = 63/150 (42%), Gaps = 11/150 (7%) Query: 31 AFVTILTEALPAG----VLPAMSGDLGVSEARA---GLLITVYALAAALTAIPMTAWTLI 83 T+ +A+ G VLP + DL S G+L+ +YAL A + A + Sbjct: 10 ILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDR 69 Query: 84 LPRRTLLLALLLGFAATNMVTAMSTGFALTLAARVVSGVFAGLLWAMVPAYAARLAPQRS 143 RR +LL L G A + A + + R+V+G+ G A+ AY A + Sbjct: 70 FGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI-TGATGAVAGAYIADITDGDE 128 Query: 144 GKAIATALAGMTVGLSLGIPAGTALGGLIG 173 A M+ G+ AG LGGL+G Sbjct: 129 R---ARHFGFMSACFGFGMVAGPVLGGLMG 155
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 33.8 bits (77), Expect = 8e-04 Identities = 27/110 (24%), Positives = 45/110 (40%), Gaps = 8/110 (7%) Query: 56 LTGAGATAVSSLF------SPAETTSASVG-IFGVVFLAISVLSFARAAQRLFEQTWELK 108 + G +S T++A+ G I V LAIS LSF A + F++ +++ Sbjct: 279 VLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTLAISPLSFLSIADK-FKRANKIE 337 Query: 109 PLSVRNTRNGLWWILTLGGYAAVTTLLSALLGGGPLGLAALACGVLVTAA 158 S R + G L + T + A L LA+++ G+ A Sbjct: 338 EYSQRFKKLGYDGDSLLAAFHKETGAIDASLTTISTVLASVSSGISAAAT 387
>PF05272#Virulence-associated E family protein Length = 892 Score = 31.2 bits (70), Expect = 0.013 Identities = 11/32 (34%), Positives = 15/32 (46%), Gaps = 4/32 (12%) Query: 28 FLPGAKIGVV----GPNGAGKSTVLKIMAGLE 55 PG K G G GKST++ + GL+ Sbjct: 589 MEPGCKFDYSVVLEGTGGIGKSTLINTLVGLD 620
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 37.6 bits (87), Expect = 8e-05 Identities = 20/130 (15%), Positives = 29/130 (22%), Gaps = 4/130 (3%) Query: 308 PAPVQTPPPPSSAPPAAYSPTTPVAPATPPPGYGPPATSQHAQHAQPTQAAQ-HAQPTQA 366 AP PP + PP P P P A + + + + Sbjct: 55 VAPADLEPPQAVQPPPE-PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQ 113 Query: 367 AQPHGPYGPPTPVQPQGPYGTPAQAQAQAQAQAHAYAPTQVPTHAQMYPGHPMPQAPQPA 426 + P P + A A + PQ P A Sbjct: 114 PKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTS--VASGPRALSRNQPQYPARA 171 Query: 427 KRKGNRGAVI 436 + G V Sbjct: 172 QALRIEGQVK 181
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 51.6 bits (123), Expect = 2e-09 Identities = 36/195 (18%), Positives = 70/195 (35%), Gaps = 16/195 (8%) Query: 23 PRLEQHQQTLEKELATVTERLE-------SVRTALTALRSLSTSPLSSST-TEAQEVKAE 74 P +E+ QT++ T ++ S + + P + +T +E E AE Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 75 DVKAEAVDVKAEAETESVAAPRIPQQAQDSVDSAAPAEVPQEPAAAAPARRTAR-KTSAP 133 + K E+ K + E A Q + V A + V A+ + K + Sbjct: 1043 NSKQES---KTVEKNEQDATETTAQNRE--VAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 134 KGRKQAPAKPKTERGQAKKAVATKSAKPAKAAAP--AKATAPAKDAKPAKATAPAKDAKP 191 K+ K E+ + + + K +P ++ A+PA+ P + K Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157 Query: 192 AKARASKKAAPAAPA 206 +++ + A PA Sbjct: 1158 PQSQTNTTADTEQPA 1172
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 32.0 bits (72), Expect = 2e-04 Identities = 18/64 (28%), Positives = 24/64 (37%), Gaps = 14/64 (21%) Query: 31 GTWVPALAFVLFPWAIIAGALAVTLGTAGIHYACHGTGRLWTAIAGTTLGIIGFVGTMTL 90 G W P L L A AG V L++ +AGTTLGI G + Sbjct: 458 GDWKP-LFLTLEKKAADAGVSYVVAL-------------LFSLLAGTTLGIWGIAIVTGI 503 Query: 91 IWAL 94 + + Sbjct: 504 LCSY 507
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.5 bits (60), Expect = 0.037 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 2/58 (3%) Query: 43 VDPSVNASVAAKAADDAVAAQSASDEASAE--AEAEAAAEAARNRPEAVRDAFAGLQA 98 V A + + + + A AS EA+A A +AAAEA R E R A A Sbjct: 190 VKLFTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAA 247
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 47.7 bits (113), Expect = 3e-09 Identities = 23/129 (17%), Positives = 45/129 (34%), Gaps = 13/129 (10%) Query: 2 LRAARRAFTQRPYAEVTIRGIAADAGVSPSLVVKHFGRKEELFNTVAD------------ 49 L A R F+Q+ + ++ IA AGV+ + HF K +LF+ + + Sbjct: 17 LDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELE 76 Query: 50 -FGPAAAELFDAPLDMLGRHMVVTLVSRRRELQSDPLLRVVFSLGNRDERSLLRDRFHEQ 108 + ++L + T+ RR L + + +G + + Sbjct: 77 YQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLE 136 Query: 109 VTDVLAARL 117 D + L Sbjct: 137 SYDRIEQTL 145
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 109 bits (275), Expect = 4e-28 Identities = 78/408 (19%), Positives = 167/408 (40%), Gaps = 22/408 (5%) Query: 24 VLAFCGVVVAVMQTIVVPLLPHIPALTGATPAAASWLVTVTLLTGAVFTPVLGRVGDMYG 83 +L+F V+ ++ + LP I PA+ +W+ T +LT ++ T V G++ D G Sbjct: 21 ILSFFSVLNEMVLNVS---LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLG 77 Query: 84 KRRVLVASLVVLVVGSVLCAVS-SHIGVLITGRALQGAALAVVPLGISILRDEL-PPERV 141 +R+L+ +++ GSV+ V S +LI R +QGA A P + ++ P E Sbjct: 78 IKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENR 137 Query: 142 LSAVALMSSTLGIGAAVGLPVAALVVENFDWHTMFWVSGVIGVIDIVLVLWCVPESPLRT 201 A L+ S + +G VG + ++ W + + +I +I + ++ + + R Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIP-MITIITVPFLMKLLKKEV-RI 195 Query: 202 RGRFDAVGALGLSGALVCLLLAVTQGADWGWTSARTVGLLVAAVVVALVWGAYELRVPTP 261 +G FD G + +S +V +L T + L+ +V+ L++ + +V P Sbjct: 196 KGHFDIKGIILMSVGIVFFMLFTTS-YSISF--------LIVSVLSFLIFVKHIRKVTDP 246 Query: 262 MVDLRVSARPAVLLTNVAALLIGFAFYANSLVTAQMVQEPKATGYGLGASLVVSGLCLLP 321 VD + ++ + +I + M++ + L ++ + + + P Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMK----DVHQL-STAEIGSVIIFP 301 Query: 322 GGVMMVALSPVSARISAKYGPKASLALAAGVIAAG-YVVRYFTSHSLWLIIAGATVVASG 380 G + ++ + + + GP L + ++ + + W + V G Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 381 TAIAYSALPALVMRGVPVSETGAANGLNTLMRSIGQAFCSATVAAVLA 428 + + + +V + E GA L + + A V +L+ Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 30.4 bits (68), Expect = 0.014 Identities = 17/51 (33%), Positives = 21/51 (41%), Gaps = 8/51 (15%) Query: 94 WAKSAGVGGW-----PGFVAAAAEAGMVGALADWFAVTALFKRPLGLPIPH 139 W+ G W P AA AG + W A T +RP LP+PH Sbjct: 50 WSAWIKPGDWLEHVSPALAGAAVSAGAEHLVVPWLAAT---ERPFELPVPH 97
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 29.0 bits (65), Expect = 0.036 Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 3/46 (6%) Query: 282 KTVVVALGINDVQQFPQETDPQRIADALRSMTQRA---HARGLRVV 324 K VV+ALG N +QQ Q+ + + D +R ++ ARG VV Sbjct: 3 KRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVV 48
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.7 bits (168), Expect = 2e-15 Identities = 28/115 (24%), Positives = 44/115 (38%), Gaps = 2/115 (1%) Query: 33 IRVLVVDDHALFRRGLEIVLAQEEDIQVVGEAGDGAEAVDKAADLLPDIVLMDVRMPKRG 92 +LV DD A R L L++ V + A A D+V+ DV MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 93 GIEACTSIKEVAPSAKIIMLTISDEEADLYDAIKAGATGYLLKEISTDEVATAIR 147 + IK+ P +++++ + A + GA YL K E+ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 29.8 bits (67), Expect = 0.035 Identities = 14/76 (18%), Positives = 31/76 (40%), Gaps = 9/76 (11%) Query: 381 RKGTRIRVVGDEQPVIAEADARRVER-VLRNLVVNAVEHG-----EGRDVVVRMAVAGGA 434 + R++ P I + +V +++ LV N ++HG +G ++++ G Sbjct: 235 QFEDRLQFENQINPAIMDV---QVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGT 291 Query: 435 VAVAVRDYGVGLKPGE 450 V + V + G Sbjct: 292 VTLEVENTGSLALKNT 307
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.4 bits (240), Expect = 2e-25 Identities = 31/141 (21%), Positives = 62/141 (43%), Gaps = 1/141 (0%) Query: 2 KGRVLVVDDDTALAEMLGIVLRGEGFEPSFVADGDKALAAFREAKPDLVLLDLMLPGRDG 61 +LV DDD A+ +L L G++ ++ DLV+ D+++P + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 IEVCRLIRAE-SGVPIVMLTAKSDTVDVVVGLESGADDYIVKPFKPKELVARIRARLRRS 120 ++ I+ +P+++++A++ + + E GA DY+ KPF EL+ I L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 EEPAPEQLAIGDLVIDVAGHS 141 + + + + G S Sbjct: 123 KRRPSKLEDDSQDGMPLVGRS 143
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 29.6 bits (66), Expect = 0.027 Identities = 18/69 (26%), Positives = 20/69 (28%), Gaps = 4/69 (5%) Query: 29 VDGSGPAGNW--SPTQPPTGQWSPPSTPGTGPGAPPPAPGWGGGPQGPGWGGPHGSGWRQ 86 DG G + GQWS P AP PAP G P P P + Sbjct: 543 KDGKVDIGTYRYRLAANGNGQWSLVGAKA--PPAPKPAPQPGPQPPQPPQPQPEAPAPQP 600 Query: 87 PPVAAKPGV 95 P Sbjct: 601 PAGRELSAA 609
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 35.6 bits (82), Expect = 3e-04 Identities = 31/148 (20%), Positives = 56/148 (37%), Gaps = 17/148 (11%) Query: 36 VVGQDPAVTGLV----VALLCRGHVLLEGVPGVAKTLLVRAL-AASLDLDTKRVQFTPDL 90 +VG+ A+ + + +++ G G K L+ RAL + V Sbjct: 139 LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAA 198 Query: 91 MPSDVTGSLVYDARTAEFS---------FQPGPVFTNLLLADEINRTPPKTQSSLLEAME 141 +P D+ S ++ F+ F+ T L DEI P Q+ LL ++ Sbjct: 199 IPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT--LFLDEIGDMPMDAQTRLLRVLQ 256 Query: 142 ERQVTVDGTPRLLPEPF-LVAATQNPIE 168 + + T G + +VAAT ++ Sbjct: 257 QGEYTTVGGRTPIRSDVRIVAATNKDLK 284
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.019 Identities = 33/165 (20%), Positives = 68/165 (41%), Gaps = 24/165 (14%) Query: 319 VLIEALFLGIVGSVLGVGAGVGLAV-GLMKLMGAMGMDLSTKDLTVAWTTPVVGLALGIV 377 L+ LFL + + L V + + G ++ A G ++T LT+ LA+G++ Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT--LTMFGMV----LAIGLL 405 Query: 378 V----TVVAAYIPARRAGKISPMAALRDAGTPADGRAGRVRAAI-GLVLTLAGGAALLAA 432 V VV K+ P A + +++ A+ G+ + L+ +A Sbjct: 406 VDDAIVVVENVERVMMEDKLPPKEATEKS-------MSQIQGALVGIAMVLSAVFIPMAF 458 Query: 433 TRADKSSEGSLFLGVGVVLTLIGFIVIGPLLAGFVVRVLSALMLR 477 S G+++ +T++ + + L+A + L A +L+ Sbjct: 459 F---GGSTGAIYRQFS--ITIVSAMALSVLVALILTPALCATLLK 498
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 103 bits (258), Expect = 7e-26 Identities = 80/400 (20%), Positives = 157/400 (39%), Gaps = 22/400 (5%) Query: 6 LAAIDGTIVSTAVPQIVGDLGGF-SVFSWLFSGYLLAVTVSLPVYGKLSDTFGRKPVLVA 64 + ++ +++ ++P I D + +W+ + ++L ++ VYGKLSD G K +L+ Sbjct: 25 FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLF 84 Query: 65 GIVLFLFGSVLCAAAWNMAA-LIAFRVVQGLGGGALQGTVQTIAADLYPLKERPKIQAKL 123 GI++ FGSV+ + + LI R +QG G A V + A P + R K + Sbjct: 85 GIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLI 144 Query: 124 STVWATSAVAGPVIGGLFAVYADWRWIFLINLPVGALALWLVVRHLHEPARTRRAAGAPR 183 ++ A GP IGG+ A Y W +L+ +P+ + + L + + Sbjct: 145 GSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKG----- 197 Query: 184 PRIDWAGALAVFATGTLLLTALVQGGVAWPWFSAPSLGLLAGSVVLGALTVVIERRAAEP 243 D G + + + ++ S+ L SV+ + V R+ +P Sbjct: 198 -HFDIKGIILMSVGIVFFMLFT----------TSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 244 VIPGWVWRRRTIASVNLALGAMGLLMVAPTVFLPTYAQSVLGLGPIAAGF-VLSVMTLSW 302 + + + L G + + +P + V L G ++ T+S Sbjct: 247 FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSV 306 Query: 303 PVSAAFSNRVYNRIGFRRTAIIGMSCALLILLAFPLLPYPGEPWQPALIMLLLGAALGLF 362 + + +R G IG++ + L L + +I+ +LG L Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG-GLSFT 365 Query: 363 QLPLIVGVQSTVGWAERGTTTASVLFCRQVGQSVGAALFG 402 + + V S++ E G + + F + + G A+ G Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.5 bits (68), Expect = 0.003 Identities = 17/49 (34%), Positives = 20/49 (40%), Gaps = 1/49 (2%) Query: 15 PGRLPKPSRRHQPPPPHDPEHLPPWQSSKPSPPPERPSAPTTPVPAPGR 63 P P P QP P P+ P Q +P PP+R P P GR Sbjct: 569 PAPKPAPQPGPQPGPQ-PPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGR 616 Score = 28.9 bits (64), Expect = 0.008 Identities = 15/48 (31%), Positives = 21/48 (43%) Query: 5 SPPPSPYSSWPGRLPKPSRRHQPPPPHDPEHLPPWQSSKPSPPPERPS 52 +PP + PG P P P PP P+ P Q +P P+ P+ Sbjct: 567 APPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPA 614
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 32.7 bits (74), Expect = 0.002 Identities = 24/155 (15%), Positives = 43/155 (27%), Gaps = 6/155 (3%) Query: 119 GTAEETVAEARKEAAEVREQAESAMAETRRRTASVLAHQEQEHSERWKTAEREVAEAEAA 178 E EA+ + E A + + + Q E E + E A+ E Sbjct: 1063 AQNREVAKEAKSNVKANTQTNEVAQSGSETKET-----QTTETKETATVEKEEKAKVETE 1117 Query: 179 QAAHHDELTEQAEARLAEARRALARTEEAARHGQEDAEAQGAELIAAARVREERVVRETE 238 + ++T Q + E + E AR + + E+ +ET Sbjct: 1118 KTQEVPKVTSQVSPK-QEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS 1176 Query: 239 RILREHEEGREEVQAHMAHVRNSLAALTGRVTPAE 273 + + V + V N P Sbjct: 1177 SNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.0 bits (72), Expect = 0.010 Identities = 26/75 (34%), Positives = 30/75 (40%), Gaps = 1/75 (1%) Query: 377 GVHHAATMLADPSMGGPGALQPPGPPGVPGAPQPPGPPGPPAP-PAPPGSTPPPGGGVHH 435 + A A PG P PP P PQPP PP PP P P PP G + Sbjct: 561 SLVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSA 620 Query: 436 AATMLAGPGQVGPSA 450 AA G VG ++ Sbjct: 621 AANAAVNTGGVGLAS 635 Score = 30.1 bits (67), Expect = 0.048 Identities = 19/60 (31%), Positives = 20/60 (33%) Query: 440 LAGPGQVGPSAPQPPGPPGMPQGGAPGPVPPNPHTPPPPAYGYPQAPTGQPTVGPGYQAV 499 L G P P P P PP P PP P P+AP QP G A Sbjct: 562 LVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAA 621
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 46.7 bits (111), Expect = 4e-08 Identities = 27/158 (17%), Positives = 53/158 (33%), Gaps = 27/158 (17%) Query: 1 MVRIRVLVVDDHRIFAESLAAALAAEPDVDVAAAGSGPAALRCLERAAAEGRGYDVMLVD 60 M +LV DD L AL+ DV + R + D+++ D Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRA-GYDVRITSNAATLWRWIAAGD-----GDLVVTD 54 Query: 61 AELGILAAARGRRAPVPVPRSGENGPVDGISLVAGVRSGQPSVHTVVLAEKDDPLRAALA 120 + + L+ ++ +P + +V++ ++ + A A Sbjct: 55 VVMP---------------------DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKA 93 Query: 121 LQAGASGWVAKDCSLQRLLTVIRGVLRDETHLPPALLT 158 + GA ++ K L L+ +I L + P L Sbjct: 94 SEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLED 131
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 35.3 bits (81), Expect = 3e-05 Identities = 16/67 (23%), Positives = 27/67 (40%), Gaps = 3/67 (4%) Query: 64 TWAHWLHVDQLWVDARHRGCGLGSRLLAEAERVAGADRACTRSRLETWGFQAP--DFYRK 121 W + ++ + V +R G+G+ LL +A A + C LET FY K Sbjct: 85 NWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFC-GLMLETQDINISACHFYAK 143 Query: 122 RGYEVSG 128 + + Sbjct: 144 HHFIIGA 150
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 151 bits (384), Expect = 1e-45 Identities = 85/334 (25%), Positives = 144/334 (43%), Gaps = 44/334 (13%) Query: 7 KYLVTGGAGYVGSVVAQHLLEAGHAVTVLDDLSTGF-------REGVPA--GAEFIEGRI 57 KYLVTG AG++G V++ LLEAGH V +D+L+ + R + A G +F + + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 58 QDAAK----WLDPSYDGVLHFAAYSQVGESVVDPEKYWVNNVGGSVALLAAMREAGVRTL 113 D + ++ V V S+ +P Y +N+ G + +L R ++ L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 114 VFSSTAATYGEPVTTPITESDATA-PTNPYGATKLAVDHMITGEAAAHGLAAVSLRYFNV 172 +++S+++ YG P + D+ P + Y ATK A + M + +GL A LR+F V Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 173 AGAYGSCGERHSPESHLIPLVLQVALGQRESISVYGDDYPTPDGTCVRDYIHVADLAEAH 232 G +G P+ L + G +SI VY G RD+ ++ D+AEA Sbjct: 182 YGPWG------RPDMALFKFTKAMLEG--KSIDVYN------YGKMKRDFTYIDDIAEAI 227 Query: 233 LLALDAATEGE----------------HLVCNLGNGNGFSVREVIETVREVTGHPVPETA 276 + D + + V N+GN + + + I+ + + G + Sbjct: 228 IRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNM 287 Query: 277 APRRAGDPAVLVASAATARERLGWTPSRADLTGI 310 P + GD A E +G+TP G+ Sbjct: 288 LPLQPGDVLETSADTKALYEVIGFTPETTVKDGV 321
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 3e-06 Identities = 26/135 (19%), Positives = 52/135 (38%), Gaps = 6/135 (4%) Query: 4 RLMVVDDHRLLAEALASALKLRGHRVLAAAAPTSGAAELVVSRAPEVCLFGTAAPAEPGA 63 ++V DD + L AL G+ V + + + + ++ + P E Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSN-AATLWRWIAAGDGDLVVTDVVMPDENA- 62 Query: 64 FDPIVRIRRERPQVAVVVLGPVPSPRGIAAAFAAGAAGYV----RHDERMEGVERAMVKA 119 FD + RI++ RP + V+V+ + A GA Y+ E + + RA+ + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 120 RAGEAAVAPQLLQGA 134 + + + G Sbjct: 123 KRRPSKLEDDSQDGM 137
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.8 bits (74), Expect = 0.005 Identities = 18/47 (38%), Positives = 19/47 (40%) Query: 25 GGFGAPTPPPADPFGKQPVTPPAGGFGAPQTPSPAGTPQTPPQQPGP 71 G P P PA G QP P PQ P P PQ P+ P P Sbjct: 564 GAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAP 610 Score = 30.8 bits (69), Expect = 0.019 Identities = 19/49 (38%), Positives = 21/49 (42%) Query: 56 PSPAGTPQTPPQQPGPGYGYPQGQPPQPGYGYPQGQPPQPGYGYPQSPV 104 P+P PQ PQ P P QPPQP P+ PQP G S Sbjct: 573 PAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAA 621
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 31.1 bits (70), Expect = 0.010 Identities = 18/79 (22%), Positives = 24/79 (30%), Gaps = 3/79 (3%) Query: 1 MTQPPSQQPPQGGFGAPQEPPQGSPQPPQGPPPGYGSPQTPGQAPGQAPGYGYPQQPGPY 60 M P +PPQ P P P+P P P + P P +P Sbjct: 49 MVTPADLEPPQAV--QPPPEPVVEPEPEPEPIP-EPPKEAPVVIEKPKPKPKPKPKPVKK 105 Query: 61 NQQQPGPYAQQPGPYNQQP 79 Q+QP + P Sbjct: 106 VQEQPKRDVKPVESRPASP 124
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.0 bits (80), Expect = 6e-04 Identities = 20/101 (19%), Positives = 25/101 (24%), Gaps = 2/101 (1%) Query: 3 QPPGQQPPQGGFGAPY-DPPPTPIQPPPSPPGYGSAPPPPGQAPGPYGAPGQAAGPYGAP 61 P QPP P +P P P P +P P P P P + P Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKP 116 Query: 62 AQPGPYGVPQPGPYGAPPQPGPYNAPPQPGPYDAPTRPGPY 102 + P P A A + P Sbjct: 117 VESRP-ASPFENTAPARLTSSTATAATSKPVTSVASGPRAL 156 Score = 33.4 bits (76), Expect = 0.002 Identities = 28/120 (23%), Positives = 34/120 (28%), Gaps = 12/120 (10%) Query: 1 MTQPPGQQPPQGGFGAPYDPPPTPIQPPPSPPGYGSAPPPPGQAPGPYGAPGQAAGPYGA 60 M P +PPQ A PP ++P P P P PP +AP P P Sbjct: 49 MVTPADLEPPQ----AVQPPPEPVVEPEPEPE---PIPEPPKEAPVVIEKPKPKPKP--- 98 Query: 61 PAQPGPYGVPQPGPYGAPPQPGPYNAPPQPGPYDAPTRPGPYNAPTQPGSYGQPPQPQPG 120 +P P Q P A P A A T P+ Sbjct: 99 --KPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVASGPRAL 156
>OUTRMMBRANEA#Outer membrane protein A signature. Length = 346 Score = 24.9 bits (54), Expect = 0.049 Identities = 13/24 (54%), Positives = 15/24 (62%), Gaps = 1/24 (4%) Query: 33 TAIALAVLLAA-PSTASAAPGPAT 55 TAIA+AV LA + A AAP T Sbjct: 4 TAIAIAVALAGFATVAQAAPKDNT 27
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.5 bits (66), Expect = 0.004 Identities = 11/54 (20%), Positives = 19/54 (35%), Gaps = 2/54 (3%) Query: 95 VMVHPRHQGKGYGRDLMDAAAQAARGMEGMEAIRL-TCRGGTGVDRFYTSCGYK 147 + V ++ KG G L+ A + A+ + L T FY + Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKE-NHFCGLMLETQDINISACHFYAKHHFI 147
>cloacin#Cloacin signature. Length = 551 Score = 30.8 bits (69), Expect = 0.006 Identities = 35/123 (28%), Positives = 46/123 (37%), Gaps = 18/123 (14%) Query: 26 SGGDKKNTDDSRPGGKGPAHAITPGASPSGPAISQQPGGRDES----DGSGSGGGDDSGT 81 SGGD + + G + G G A S G E+ GSGSG G+ Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGA-SDGSGWSSENNPWGGGSGSGIHWGGGS 60 Query: 82 GAGSDGGASDGGNGADGTDTGSGSDTGAGGASASGATIGQQVPAGSSLPDCAAGALQLSL 141 G G+ GG + G G+ G SA A + PA L AG L +S+ Sbjct: 61 GHGNGGGNGNSGGGS----------GTGGNLSAVAAPVAFGFPA---LSTPGAGGLAVSI 107 Query: 142 STE 144 S Sbjct: 108 SAG 110
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 88.3 bits (219), Expect = 2e-22 Identities = 35/121 (28%), Positives = 55/121 (45%), Gaps = 1/121 (0%) Query: 1 MAETHVLFVEDDDVIREATQLALERDGFVVTAMPDGLSGLDAFRADRPDIALLDVMVPGL 60 M +L +DD IR AL R G+ V + + A D+ + DV++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 DGVSLCRRIRDE-STVPVIMLSARADSIDVVLGLEAGADDYVTKPFDGAVLVARIRAVLR 119 + L RI+ +PV+++SA+ + + E GA DY+ KPFD L+ I L Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 120 R 120 Sbjct: 121 E 121
>TYPE3OMBPROT#Type III secretion system outer membrane B protein family signature. Length = 538 Score = 30.8 bits (69), Expect = 0.013 Identities = 24/109 (22%), Positives = 44/109 (40%), Gaps = 9/109 (8%) Query: 186 VREAVGGVVQDETDELARAVDA-------LTDALNERIEAERRVTADIAHELRTPVTGLL 238 +R V + + RAV A ++ AL R E + + +L+ T LL Sbjct: 223 IRHGVISAYGLKKNSSERAVAARNKAEELVSAALYSRPELLSQALSGKTVDLKIVSTSLL 282 Query: 239 TAAELLPPGRPTELVRDRAQAMRTLVEDVLEVARLDSASERAELQEIEL 287 T L G +++D+ A++ L E +L + L+E+ + Sbjct: 283 TPTSLT--GGEESMLKDQVNALKGLNSKRGEPTKLLIRNSDGLLKEVSV 329
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 155 bits (394), Expect = 6e-44 Identities = 96/410 (23%), Positives = 182/410 (44%), Gaps = 18/410 (4%) Query: 30 VMLALMITMLLAMLDNLIVGTAMPTIVGDLGGLEH-LSWVVTAYTLATAASTPIWGKLGD 88 +++ L I ++L+ +++ ++P I D +WV TA+ L + T ++GKL D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 89 MYGRKGIFLTSIVLFLIGSVLSGMAQDMGQ-LIGFRAVQGLGAGGLMVGVMAIIGDLVPP 147 G K + L I++ GSV+ + LI R +QG GA VM ++ +P Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 148 RERGKYQGMMAGVMAIAMIGGPLVGGTITDHLGWRWSFYINLPLGAVALAMVTAVLHLPK 207 RGK G++ ++A+ GP +GG I ++ WS+ + +P+ + + + + L K Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH--WSYLLLIPMITI-ITVPFLMKLLKK 191 Query: 208 RERTEAKVDYLGAGLLTLGITAIVLVTTWGGSEYDWNSAVIMELMAIGVASLVGFFFVET 267 R + D G L+++GI +L TT Y + + + V S + F Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTT----SYSIS------FLIVSVLSFLIFVKHIR 241 Query: 268 KAAEPIIPLHIFRNRNFTLMSVVGFMSGFVMFGAVLFLPLFQQSVQGASATNSG-LLLLP 326 K +P + + +N F + + G + + G V +P + V S G +++ P Sbjct: 242 KVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFP 301 Query: 327 MLLSMMVVSLIAGRVTTSTGKYKIFPVVGSVLMVTGLFLLSQMDTGTTRFTSGIYMAVLG 386 +S+++ I G + G + +G + S + T+ F + I + VLG Sbjct: 302 GTMSVIIFGYIGGILVDRRGPLYVL-NIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLG 360 Query: 387 AGMGFLMQITMLVAQNSVEMKDMGVASSATTLFRTLGSSFGVAIMGALFT 436 G+ F + + +S++ ++ G S L G+AI+G L + Sbjct: 361 -GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 78.1 bits (192), Expect = 3e-20 Identities = 35/100 (35%), Positives = 50/100 (50%), Gaps = 2/100 (2%) Query: 1 MGSTPQPRRGNTRQRIQDVALELFAEQGYEKTSLREISERLDVTKAALYYHFKTKEDILV 60 M + TRQ I DVAL LF++QG TSL EI++ VT+ A+Y+HFK K D+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 SIFDDLNRPVEELIE--WGRGQPHNLETKKEILRRYSEAL 98 I++ + EL + L +EIL E+ Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLEST 100
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 32.9 bits (75), Expect = 0.006 Identities = 34/179 (18%), Positives = 58/179 (32%), Gaps = 24/179 (13%) Query: 499 EESSRLLRMEDELHKRVIGQKDAIKAL---SQAIRRTRAGLKDPKRPGGSFIFAGPSGVG 555 R L ++ L S A++ L + + + G SG G Sbjct: 113 GIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTG 172 Query: 556 KTELSKTLAEFLFGDEDALIALDMSEFSEKHTVSRLFGSPPGYVGYEEGGQLTEKVRRKP 615 K +++ L ++ +A++M+ S LFG E G T R Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRST 224 Query: 616 --FS-----VVLFDEVEKAHPDIFNSLLQILEDG---RLTDSQGRVVDFKNTVIIMTTN 664 F + DE+ D LL++L+ G + D + I+ TN Sbjct: 225 GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN 280
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 38.4 bits (89), Expect = 5e-06 Identities = 19/74 (25%), Positives = 32/74 (43%), Gaps = 5/74 (6%) Query: 70 DARVIGCGALHVMWEDLAEVRTLAVDHSIRGAGVGHQVLDKLLQTARWLGVRRVFCLTFE 129 + IG + W A + +AV R GVG +L K ++ A+ + T + Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 130 VD-----FFAKHGF 138 ++ F+AKH F Sbjct: 133 INISACHFYAKHHF 146
>PERTACTIN#Pertactin signature. Length = 922 Score = 32.4 bits (73), Expect = 0.001 Identities = 22/90 (24%), Positives = 35/90 (38%) Query: 100 PVAAALLERCQALAERSVRARLAGRSAPPTAPAPRSRLLALPGGRAADAEPERPKTPAAP 159 P + + Q + LA + R RL A G+ + + P P Sbjct: 515 PASGNTMLLVQTPRGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPPAPKPA 574 Query: 160 PRPAPPPERPAPKPSEVFPPRRPVPPPQQR 189 P+P P P P+P + P +P PPQ++ Sbjct: 575 PQPGPQPGPQPPQPPQPPQPPQPPQPPQRQ 604
>PF03309#Bvg accessory factor Length = 271 Score = 333 bits (855), Expect = e-118 Identities = 137/269 (50%), Positives = 190/269 (70%), Gaps = 12/269 (4%) Query: 1 MLLTIDVGNTHTVLGLFDGE----EIVEHWRISTDARRTADELAVLLQGLMGMHPLLGEE 56 MLL IDV NTHTV+GL G ++V+ WRI T+ TADELA+ + GL+G Sbjct: 1 MLLAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTIDGLIGDDA----- 55 Query: 57 LGDGIEGIAICSTVPAVLHELREVTRRYYGDVPAVLVEPGIKTGVPILMDNPKEVGADRI 116 + + G + STVP+VLHE+R + +Y+ +VP VL+EPG++TG+P+L+DNPKEVGADRI Sbjct: 56 --ERLTGASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGADRI 113 Query: 117 INAVAAVDLYGGPAIVVDFGTATTFDAVSARGEYTGGVIAPGIEISVEALGVKGAQLRKI 176 +N +AA YG AIVVDFG++ D VSA+GE+ GG IAPG+++S +A + A LR++ Sbjct: 114 VNCLAAYHKYGTAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRV 173 Query: 177 ELARPRSVIGKNTVEAMQSGIIYGFAGQVDGVVARMKKELAADPD-DVTVIATGGLAPMV 235 EL RPRSVIGKNTVE MQ+G ++GFAG VDG+V R++ ++ DV V+ATG AP+V Sbjct: 174 ELTRPRSVIGKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVAVVATGHTAPLV 233 Query: 236 LGESSVIDEHEPWLTLIGLRLVYERNVSR 264 L + ++ ++ LTL GLRLV+ERN + Sbjct: 234 LPDLRTVEHYDRHLTLDGLRLVFERNRAN 262
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.029 Identities = 9/33 (27%), Positives = 15/33 (45%), Gaps = 1/33 (3%) Query: 134 HVEDGDRVAPGQKLLTVT-TRTRDLLTGERSAL 165 V++G+ V G LL +T +S+L Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSL 143
>FbpA_PF05833#Fibronectin-binding protein Length = 577 Score = 29.5 bits (66), Expect = 0.005 Identities = 9/44 (20%), Positives = 19/44 (43%), Gaps = 1/44 (2%) Query: 51 EVQKVIAKEAKKRREAAEAF-AQGGRTEQAEREKAEGELLDAYL 93 ++QK++ + + + + E + K GELL A + Sbjct: 303 DLQKIVMNNINRCTKKDKILNNTLKKCEDKDIFKLYGELLTANI 346
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 127 bits (320), Expect = 8e-34 Identities = 83/421 (19%), Positives = 174/421 (41%), Gaps = 28/421 (6%) Query: 17 VLLTLAAGQFLMALDSSVMNVSIATVADDVGTTVTGIQGAITAYTLVMAMFMIPGGKAGA 76 +L+ L F L+ V+NVS+ +A+D TA+ L ++ GK Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 77 LIGRKRAFVIGCGIYGCGSLITALAPNLPVLLLGWSFLEGVGAALILPAIVALVAGNFAT 136 +G KR + G I GS+I + + LL+ F++G GAA ++ +VA Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 137 ERRPAAYGLVAAAGAVAIALGPLIGGVATTYFSWRWVFAGEVLVVLGILVLARRIADAAS 196 E R A+GL+ + A+ +GP IGG+ Y W ++ ++ ++ + L + + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR 194 Query: 197 DERPRIDLVGAALSALGLGIFVYGVLRSDEWGWFRPKPDAPSWLGVSLVVWLMLAGLLLV 256 + D+ G L ++G+ F+ S + L+V ++ Sbjct: 195 IKGH-FDIKGIILMSVGIVFFMLFT-TSYSISF--------------LIVSVLSFL---- 234 Query: 257 WLFLRREARLVEQRREPLIHPSMLENKQLTGGLTMFFFQYLVQMGVFFVVPLYLSVALGL 316 +F++ ++ +P + P + +N G+ + G +VP + L Sbjct: 235 -IFVKHIRKV----TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQL 289 Query: 317 SALTTGAR-LLPLSITLLAAAVLIPRFFPDVSPRRVVRLGVLALLSGAVALMAALDADAG 375 S G+ + P +++++ + P V+ +GV L L A+ + Sbjct: 290 STAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS--FLTASFLLETT 347 Query: 376 AEIVTIPLLLIGLGMGSLASQLGSVTVSAVPEQQSAEVGGVQNAVTNLGASLGTALAGSI 435 + +TI ++ + G+ + + ++ S++ +Q++ + N + L G A+ G + Sbjct: 348 SWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGL 407 Query: 436 M 436 + Sbjct: 408 L 408
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 187 bits (477), Expect = 6e-59 Identities = 89/366 (24%), Positives = 138/366 (37%), Gaps = 64/366 (17%) Query: 1 MRVLVTGGAGFIGSHIVKTLISRGHEPVVLDSL-------LPTAHRSVTGPPELGGAAWV 53 M+ LVTG AGFIG H+ K L+ GH+ V +D+L L A + P G + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP---GFQFH 57 Query: 54 RGDVRDRDVVRQ--ALSGMDAVCHQAAMVGLGKDFADAPDYVGCNDLGTAVLLAAMAETG 111 + D+ DR+ + A + V + + + Y N G +L Sbjct: 58 KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNK 117 Query: 112 VERLVLAGSMVVYGEGRYECPSHGWVRPGPRAEQDLVSGRFEPLCPQCGAELSPGLVGED 171 ++ L+ A S VYG R P + +D Sbjct: 118 IQHLLYASSSSVYGLNRKM----------PFST-------------------------DD 142 Query: 172 APADPRNVYATTKLAQEHLAAAWARTTGGRAVSLRYHNVYGPRMPRDTPYAGVASLFRSA 231 + P ++YA TK A E +A ++ G A LR+ VYGP D F A Sbjct: 143 SVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMAL----FKFTKA 198 Query: 232 LARGEAPRVFEDGGQRRDFVHVRDVAAANAVALEAI-------DVRVPGALTS------Y 278 + G++ V+ G +RDF ++ D+A A + I V S Y Sbjct: 199 MLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVY 258 Query: 279 NTGSGDPHTVGEMAAALAAGHGGPSPVVTGEFRLGDVRHITADSSRLKSELGWRPEVGFA 338 N G+ P + + AL G + + GDV +AD+ L +G+ PE Sbjct: 259 NIGNSSPVELMDYIQALEDALGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVK 318 Query: 339 EGMAEF 344 +G+ F Sbjct: 319 DGVKNF 324
>PF07299#Fibronectin-binding protein (FBP) Length = 219 Score = 41.4 bits (97), Expect = 4e-07 Identities = 28/120 (23%), Positives = 50/120 (41%), Gaps = 16/120 (13%) Query: 2 EPLSEKQIRSSFVNCTKGEAARLRLPLDFDELPWDDLDFLGWVDPGAPLRAHLVVSRAQG 61 + ++ + ++ F +A +L+LP D +EL +L +L W+D G+ R ++ + Sbjct: 92 QEVTAQTLKKLF-----PKAKKLKLP-DMEELDMKELSYLSWIDKGSS-RKFIIAKNDKN 144 Query: 62 PL-GISLRIPSVRRTSAVKSSMCQICLTGHASSGVTLLAAPLAGARGREGNTVGIYICAD 120 G+ S K S+C +C H V + + G G YIC D Sbjct: 145 KFVGLQGTF-----QSLNKKSICSLC---HGHEEVGMFLVEIKGDIPGTFVKKGNYICKD 196
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 28.2 bits (63), Expect = 0.021 Identities = 13/41 (31%), Positives = 19/41 (46%) Query: 91 NSKWKRDPKALKAQEKCASLSLPIPESVLKEQRPELSEEEI 131 K D AL ++K A L + I + + LS+EEI Sbjct: 5 KEKEILDVSALTGKQKAAILLVSIGSEISSKVFKYLSQEEI 45
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 7e-04 Identities = 16/106 (15%), Positives = 34/106 (32%), Gaps = 21/106 (19%) Query: 431 LRQVVGNLVVNAVRVTAPGGTVNLALVRDGDLAVIQVRDTGKGIPPEDLPHLFDRFWRAD 490 ++ +V N + + + GG + L +D ++V +TG Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT------------ 307 Query: 491 AARGRATGGSGLGLSIAR---QIVTDHRGRIDVESTVGVGTTFSVV 533 +G GL R Q++ +I + G ++ Sbjct: 308 ------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 8e-20 Identities = 40/164 (24%), Positives = 76/164 (46%), Gaps = 10/164 (6%) Query: 3 ARILVAEDDVKQARLIGIYLEREGNEVQIVADGRSAIDRARSSRPDLIVLDVMMPNVDGL 62 A ILVA+DD ++ L R G +V+I ++ + + DL+V DV+MP+ + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 DVCRILRAE-SQVPILLLTARTTEEDMLLGLDLGADDYMAKPYSPRELTARV-RALLRRS 120 D+ ++ +P+L+++A+ T + + GA DY+ KP+ EL + RAL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 121 KAAGRTGPAVLTAGDLEIDTARFE------VRVAG--VPVVLTG 156 + + L +A + R+ + +++TG Sbjct: 124 RRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITG 167
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 28.1 bits (62), Expect = 0.028 Identities = 12/34 (35%), Positives = 19/34 (55%) Query: 157 PTEPVAFAREVFARLGVYEGEKLDAWYRLFHDSD 190 PT PV + L + +G+++D +RL HDS Sbjct: 100 PTNPVTGEIPTLSALDIPDGDEVDVQWRLVHDSA 133
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 37.6 bits (87), Expect = 9e-05 Identities = 21/111 (18%), Positives = 29/111 (26%), Gaps = 2/111 (1%) Query: 314 PAAPTALQDAAPPATKPPAQQPPGGVQAMPAVTTATPPPSQAPAPAPTPTPTPAYGYPSM 373 P Q + P +PP VQ P P P P P P P Sbjct: 41 IELPAPAQPISVTMVAPADLEPPQAVQPPPEPV-VEPEPEPEPIPEPPKEAPVVIEKPKP 99 Query: 374 PAQPHPGQGQPYGYGYP-AAPQQQAPQPPGSGPTPSYGPTYPTPVPQPEPA 423 +P P + P + P P P+ + +P Sbjct: 100 KPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPV 150
>INTIMIN#Intimin signature. Length = 939 Score = 30.0 bits (67), Expect = 0.036 Identities = 50/290 (17%), Positives = 79/290 (27%), Gaps = 28/290 (9%) Query: 288 YVYKQDTTKPVRTYDFPNTGNSSGADTLEDAGLAWAPDTSRLFAVTVNSYGVRSLRVLTD 347 YV V + GNSS L +TV S G V Sbjct: 517 YVQGGSNVYKVTARAYDRNGNSSNNVLL---------------TITVLSNG---QVVDQV 558 Query: 348 AVKSATTVTVNAPAKSERGKKLTVTGRVKSEGAFPVGAKATVTRTDIESPKGKTLPAVTL 407 V T +A A + +T T VK G + L A + Sbjct: 559 GVTDFTADKTSAKADGT--EAITYTATVKKNGVAQANVPVSFNIVS----GTAVLSANSA 612 Query: 408 KSDGSFSFTDTPTAG--GQVTYKVSYAGDVAHSAASGSDKVAVSRAATSLTLNRNKALYS 465 ++GS T T + GQV A + A+ V A+ + +K Sbjct: 613 NTNGSGKATVTLKSDKPGQVVVSAKTAEMTSALNANAVIFV-DQTKASITEIKADKTTAV 671 Query: 466 YGTDVSFTAHLGTTYKNRTVELWVDPFGPDKPKKLVKTGKVNAKGNLSTTV-DMTRDTTV 524 + T + ++ V F K T K + G T+ T ++ Sbjct: 672 ANGQDAITYTVKVMKGDKPVSNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSL 731 Query: 525 TAVFKGDGRYASKTVTSTAYAKVRVSTSVSKQYKTAKIGSTPYAYFHKKT 574 + D K + + + + T G P + Sbjct: 732 VSARVSDVAVDVKAPEVEFFTTLTIDDGNIEIVGTGVKGKLPTVWLQYGQ 781
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 27.3 bits (60), Expect = 0.033 Identities = 14/83 (16%), Positives = 36/83 (43%) Query: 1 MRPRSSYKAPPSQSLIYSAVLQSMAEHGPRRMNMALAARIADTDRQLLYRNWPDRNVLVR 60 M ++ +A ++ I L+ ++ G ++ A+ A R +Y ++ D++ L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 ESAESELQRVLFVASDLRSEQEG 83 E E + + + +++ G Sbjct: 61 EIWELSESNIGELELEYQAKFPG 83
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.6 bits (162), Expect = 7e-16 Identities = 25/93 (26%), Positives = 46/93 (49%), Gaps = 2/93 (2%) Query: 4 RRPRAKAADKRQRLMAAAARVLHEQGVERTTIADIAQAADVPAGNVYYYFKTKGELVEAA 63 R+ + +A + RQ ++ A R+ +QGV T++ +IA+AA V G +Y++FK K +L Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 64 LSEHTRHLEALTGRL--DQLTDPRERLKGLVDA 94 ++ L DP L+ ++ Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIH 95
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.014 Identities = 29/126 (23%), Positives = 46/126 (36%), Gaps = 35/126 (27%) Query: 2 IVVTGATGNVGRALVRMLTDAGVPVTAV-------------ARHITDADMPPGVRATAAD 48 +VTGA G +G + + L +AG V + AR A PG + D Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ--PGFQFHKID 60 Query: 49 LAGPAGLRVAFD--GAEALFLLVAG-------DDPHG-----------ILEVAKTAGVRK 88 LA G+ F E +F+ ++PH ILE + ++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 89 VVLLSS 94 ++ SS Sbjct: 121 LLYASS 126
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 150 bits (381), Expect = 2e-42 Identities = 87/410 (21%), Positives = 160/410 (39%), Gaps = 18/410 (4%) Query: 24 RRWTMLALICAAQFMLVLDVTVVNVALPDMAVDLDLGRTALTWVVTAYTLCFAGLMLLGG 83 R +L +C F VL+ V+NV+LPD+A D + + WV TA+ L F+ + G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 84 RLADVLGARRTLLAGLVVFTAASLVCGLAGSGAT-LIGGRIAQGVGAALLSPAALSLVTT 142 +L+D LG +R LL G+++ S++ + S + LI R QG GAA + +V Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVAR 130 Query: 143 SFHGKERNRALGVWAAIGGTGSAIGVLAGGALTSGPGWQWVFYVNVPVGIALLVAVPAFV 202 + R +A G+ +I G +G GG + W ++ +P + ++ VP + Sbjct: 131 YIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLL--LIP--MITIITVPFLM 186 Query: 203 P-PRPERPSAGRLDVAGALLATAGTGSLVYGLVTAGDFGWSAAWTLVPVVGAAALYAAFA 261 + E G D+ G +L + G + T+ + L ++ F Sbjct: 187 KLLKKEVRIKGHFDIKGIILMSVGIVFFMLF-TTSYSISFLIVSVLSFLI--------FV 237 Query: 262 AVERVAREPLMDLRMFTRRPVLAGAFLMLFATALLIAFFFLGSVFLQHGRGFGPMRTGLV 321 R +P +D + P + G + F + ++ G V Sbjct: 238 KHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSV 297 Query: 322 FL-PVAVAVGIGAHIGSRLVGTVGSRATAVGAMVIAAGGCLPLTRVGADSSVYGGLLPGL 380 + P ++V I +IG LV G + + L + + +S + + + Sbjct: 298 IIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWF--MTIII 355 Query: 381 AVAAFGLGAVFVTATATALGMVAHEEAGLASGVVNTFHEVGGSIGVAVGS 430 GL + + +EAG ++N + G+A+ Sbjct: 356 VFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVG 405
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 62.0 bits (150), Expect = 6e-14 Identities = 31/177 (17%), Positives = 52/177 (29%), Gaps = 15/177 (8%) Query: 5 PPPAGPRAEAKRQAIVKAAREAFLREGF-GVGMDAIAAEAGVSKVTVYNHFGSKEALFTA 63 A+ RQ I+ A F ++G + IA AGV++ +Y HF K LF+ Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 64 VITGALDEPLGGPSTKALAGLPDAADLRTAFLNTARAWVSAVRGNADVIALRNLVAAELH 123 + + D R + V + R L+ + Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLS-------VLREILIHVLESTVTEERRRLLMEIIF 114 Query: 124 RFPELAGAW------QHHGPAGHHPAVADALRSLAERGRLDIP-DLETAIIQLYALL 173 E G Q + + + L+ E L A I + + Sbjct: 115 HKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 48.8 bits (116), Expect = 5e-10 Identities = 19/75 (25%), Positives = 34/75 (45%), Gaps = 3/75 (4%) Query: 74 RARIEDVVVDTEARGQGIAALLTQEALTLAREAGARTVDLTSRPDRAAANRLYERLGFR- 132 A IED+ V + R +G+ L +A+ A+E + L ++ +A Y + F Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFII 148 Query: 133 -ARESTVYR-FPMDG 145 A ++ +Y FP Sbjct: 149 GAVDTMLYSNFPTAN 163
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 46.2 bits (109), Expect = 2e-07 Identities = 40/253 (15%), Positives = 81/253 (32%), Gaps = 13/253 (5%) Query: 206 AARAKQEADIAEAIAKRASE---QARLKAAEEIAIAERTFYLKQAEI---KAETEAAAAK 259 A +KQE+ E + A+E Q R A E A + + E+ +ET+ Sbjct: 1041 AENSKQESKTVEKNEQDATETTAQNREVAKE--AKSNVKANTQTNEVAQSGSETKETQTT 1098 Query: 260 ANAAGPLAEAARQQEVLAEQEKVAQRQAALTDRELDTKVRKPADAARYQAEQEAEARRIA 319 E + +V E+ + + + ++ K + + + QAE E Sbjct: 1099 ETKETATVEKEEKAKVETEKTQEVPKVTS----QVSPKQEQS-ETVQPQAEPARENDPTV 1153 Query: 320 QVKEAEADAERSRLTGQGEKLHRSALADAVRIEGEAEAAAIAAKGAAEAEAMQKKADAFA 379 +KE ++ + T Q K S + V + + + Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 380 QYGDAAVLQMLVEVLPHVVAKASEPLSAIDKMTVISTDGASQLSRTVTDNVAQGMELLSS 439 + + + V S+ D+ TV D S + V + + ++ Sbjct: 1214 ESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVAL 1273 Query: 440 TTGVDLAALLKNL 452 G ++ + L Sbjct: 1274 NVGKAVSQHISQL 1286 Score = 38.9 bits (90), Expect = 5e-05 Identities = 44/311 (14%), Positives = 97/311 (31%), Gaps = 26/311 (8%) Query: 175 SLSGQGLILDAFQIQDITTEGSYLEDLGRPEAARAKQEAD---IAEAIAKRASEQARLKA 231 SL G + L A++ + G Y DL PE + Q D I +A + Sbjct: 956 SLVGNTVDLGAWKYKLRNVNGRY--DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSN 1013 Query: 232 AEEIAIAERTFYLKQAEIKAETEAAAAKANAAGPLAEAARQQEVL-------AEQEKVAQ 284 EEIA + E A A + +AE ++Q+ A + Sbjct: 1014 NEEIA--------RVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQN 1065 Query: 285 RQAALTDRELDTKVRKPADAARYQAEQEAEARRIAQVKEAEADAERSRLTGQGEKLHRSA 344 R+ A + + + A+ +E + + E++++ + + Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 345 LADAVRIEGEAEAAAIAAKGAAEAEAMQKKADAFAQYGDAAVLQMLVEVLPHVVAKASEP 404 + + ++E A+ A E + + +Q A + + V + Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 405 LSAIDKMTVISTDGASQLSRTVTDNVAQGMELLSSTTG-VDLAALLKNLKGGAASATSAD 463 + ++ + + + T V + ++ N++ S+ Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSS---- 1241 Query: 464 LPDAAPAASAN 474 D + A + Sbjct: 1242 -NDRSTVALCD 1251
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 80.5 bits (198), Expect = 1e-17 Identities = 55/294 (18%), Positives = 84/294 (28%), Gaps = 20/294 (6%) Query: 153 AAEVEAPAEPQPAEPVVAPTAEAEPQPAPVVAETEPEPVAAPAEAEPEPAAVAAEAEVEA 212 + P Q P + P +A + PV PA A P + Sbjct: 994 TTNITTPNNIQADVP-------SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046 Query: 213 PSETEPKAETAAVEAEPAAELEPVEAEAPTEAEP---EPVAAPADEAEAPAEPKAEPAT- 268 S+T K E A E EA++ +A E + ++ E E AT Sbjct: 1047 ESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATV 1106 Query: 269 -AEVKAPAETEPDAEPAAVEAEPEP-----AAELEPVEAEAPAEAEVKAPTETEPDAEPA 322 E KA ETE E V ++ P E + V A Sbjct: 1107 EKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTA 1166 Query: 323 AVE--AEPEPAAELEPVEVEAPAEAEPEPVAAPADEAEAPAEPKAEPATAEVKAPTEPQP 380 E A+ + +PV V P + A +P ++ + Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226 Query: 381 VAAEAEVKAPAETEPKAEIATGTAPEATPTSEPALPLARVKSHAPGLVDSYKAA 434 V + PA T + + L AR K+ ++ KA Sbjct: 1227 VRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFV-ALNVGKAV 1279 Score = 77.8 bits (191), Expect = 7e-17 Identities = 52/224 (23%), Positives = 79/224 (35%), Gaps = 13/224 (5%) Query: 201 PAAVAAEAEVEAPSETEPKAETAAVEAEPAAELEPVEAEAPTEAEPEPVAAPADEAEAPA 260 P V+ + T P A V + P+ E + P P A P++ E A Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAP-ATPSETTETVA 1041 Query: 261 E-PKAEPATAEVKA--PAETEPDAEPAAVEAEPEPAAELEPVE-AEAPAEAEVKAPTETE 316 E K E T E ET A EA+ A + E A++ +E + TET+ Sbjct: 1042 ENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETK 1101 Query: 317 PDAEPAAVEAEPEPAAELEPVEVEAPAEAEPEPVAAPADEAEAPAEPKAEPATAE-VKAP 375 E A VE E + E E + ++ P ++ + AEP E +K P Sbjct: 1102 ---ETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEP 1158 Query: 376 TEPQPVAAEAEVKAPAETEPKA--EIATGTAPEATPTSEPALPL 417 A+ + PA+ + T + T S P Sbjct: 1159 QSQT--NTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPE 1200 Score = 73.9 bits (181), Expect = 1e-15 Identities = 58/306 (18%), Positives = 89/306 (29%), Gaps = 31/306 (10%) Query: 96 TVPAQGSAPRPKPKPAEPEAEVAEPVAAKPDEVEVEPVATEPEAAPTAEVKPEAAPAAAE 155 TV + P A+ DE V P A + T E E + ++ Sbjct: 991 TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSE-TTETVAENSKQESK 1049 Query: 156 VEAPAEPQPAEPVVAPTAEAEPQPAPVVAETEPEPVAAPAEAEPEPAAVAAEAEVEAPSE 215 E E Q V E + A E A +E + +E Sbjct: 1050 TVEKNEQDATET--------TAQNREVAKEAKSNVKANTQTNEV--AQSGSETKETQTTE 1099 Query: 216 TEPKAETAAVEAEPAAELEPVE-AEAPTEAEPEPVAAPADEAEAPAEPKAEPAT------ 268 T+ ETA VE E A++E + E P P E +P+AEPA Sbjct: 1100 TK---ETATVEKEEKAKVETEKTQEVPKVTSQVS---PKQEQSETVQPQAEPARENDPTV 1153 Query: 269 --AEVKAPAETEPDAEPAAVEAEPEPAAELEPVEAEAPAEAEVKAPTETEPD-AEPAAVE 325 E ++ T D E A E + + V+ P T P +P Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNS 1213 Query: 326 AEPEPAAELEPVEVEA-PAEAEPEPVAAPADEAEAPAE---PKAEPATAEVKAPTEPQPV 381 V + P EP ++ A + ++ +A + + Sbjct: 1214 ESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVAL 1273 Query: 382 AAEAEV 387 V Sbjct: 1274 NVGKAV 1279 Score = 65.5 bits (159), Expect = 5e-13 Identities = 55/253 (21%), Positives = 83/253 (32%), Gaps = 20/253 (7%) Query: 82 SDLVAAAFDKASIATVPAQGSAPRPKPKPAEPEAEVAEPVAAKPDEVEVEPVATEPEAAP 141 +D+ + + IA V AP P P PA P +E E VA + E +A Sbjct: 1005 ADVPSVPSNNEEIARVD---EAPVPPPAPATP-SETTETVAENSKQESKTVEKNEQDATE 1060 Query: 142 TAEVKPEAAPAAAEVEAPAEPQPAE--PVVAPTAEAEPQPAPVVAETEPEPVA-APAEAE 198 T E A A A Q E + T E + A E E A E Sbjct: 1061 TTAQNREVAKEAKS-NVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119 Query: 199 PEPAAVAAEA--EVEAPSETEPKAETAAVEAEPAAELEPVEAEAPTEAEPEPVAAPADEA 256 E V ++ + E +P+AE A E +P ++ +++ T A+ E PA E Sbjct: 1120 QEVPKVTSQVSPKQEQSETVQPQAEPAR-ENDPTVNIKEPQSQTNTTADTE---QPAKET 1175 Query: 257 EAPAEPKAEPATAEVKAPAETEPDAEPAAVEAEPEPAAELEPVEAE------APAEAEVK 310 + E +T + E +P +E V+ Sbjct: 1176 SSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVE 1235 Query: 311 APTETEPDAEPAA 323 T + D A Sbjct: 1236 PATTSSNDRSTVA 1248 Score = 61.2 bits (148), Expect = 1e-11 Identities = 44/270 (16%), Positives = 82/270 (30%), Gaps = 24/270 (8%) Query: 16 AEQDAPTATVPPQTERTAPAESEPVTVTVNESAAETASVRETASATKASVPAPASHRSAT 75 + D P+ VP E A + PV + +ET S ++ + + AT Sbjct: 1003 IQADVPS--VPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT-VEKNEQDAT 1059 Query: 76 GDSGLASDLVAAAFDKASIATVPAQGSAPRPKPKPAEPEAEVAEPVAAKPDEVEVEPVAT 135 + ++ A T + + + K + K ++ +VE T Sbjct: 1060 ETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKT 1119 Query: 136 EPEAAPTAEVKPEAAPAAAEVEAPAEPQPAEPVVAPTAEAEPQPAPVVAETEPEPVAAPA 195 + T++V P+ Q V P AE + P V E P Sbjct: 1120 QEVPKVTSQVSPK--------------QEQSETVQPQAEPARENDPTVNIKE------PQ 1159 Query: 196 EAEPEPAAVAAEAEVEAPSETEPKAETAAVEAEPAAELEPVEAEAPTEAEPEPVAAPADE 255 A A+ + + +P E+ V + P E P +P + +++ Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP-ENTTPATTQPTVNSESSNK 1218 Query: 256 AEAPAEPKAEPATAEVKAPAETEPDAEPAA 285 + V+ + D A Sbjct: 1219 PKNRHRRSVRSVPHNVEPATTSSNDRSTVA 1248
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.001 Identities = 21/109 (19%), Positives = 37/109 (33%), Gaps = 19/109 (17%) Query: 274 RLLLAQLVANLLANAVTYNVPDGTVEVSLVTAGDGVLLEVRNTGPVVDAADIPGLFEPFR 333 +L+ LV N + + + G + + V LEV NTG + Sbjct: 257 PMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL-------------- 302 Query: 334 RGEGKDRMGRGSGLGLSIVRS-IAVAHGG-TVTAVPGPEGGLAVTVRLP 380 +G GL VR + + +G + +G + V +P Sbjct: 303 ---ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 78.3 bits (193), Expect = 5e-19 Identities = 36/148 (24%), Positives = 66/148 (44%), Gaps = 1/148 (0%) Query: 10 RVLVAEDEEILAELVATGLRRAGFAVDTVYSGDAALAYLGLHDYDVVVLDRDLPRVHGDD 69 +LVA+D+ + ++ L RAG+ V + ++ D D+VV D +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 70 VARGLVASGSRTRILMLTAAGSMEDRVAGLDLGADDYLGKPFEFPELVSRV-RALRRRSA 128 + + + +L+++A + + + GA DYL KPF+ EL+ + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 129 RPVPPQLERHGIRLDTVRRTASREGREL 156 RP + + R A +E + Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRV 152
>PF06776#Invasion associated locus B Length = 214 Score = 30.7 bits (69), Expect = 0.018 Identities = 14/36 (38%), Positives = 18/36 (50%) Query: 2 RQVSRALTAALAAMALSAGAPGPAHAQPAAESIPGA 37 R +R + A A+ALS G A AQ A S+ G Sbjct: 47 RNGARLMLAGAMAIALSFGWSDRADAQGAVRSVHGD 82
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 29.0 bits (65), Expect = 0.022 Identities = 27/108 (25%), Positives = 44/108 (40%), Gaps = 12/108 (11%) Query: 11 STVLGRRLGGELQSLRVAAGKTQRQAAEVLSATPTKVVKMESGWVPMRDPDIAALCTLYG 70 S V R+ A G A ++L TP + + PM+D IA + Sbjct: 37 SVVAIRQDRAGSPKSVAAVGH---DAKQMLGRTPGNIAAIR----PMKDGVIAD----FF 85 Query: 71 VSEPRILAHLLELAKTDRERRKVKGWWNETPTLATQVEYIAMEDAAVK 118 V+E ++L H ++ ++ R P ATQVE A+ ++A Sbjct: 86 VTE-KMLQHFIKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQG 132
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 30.5 bits (68), Expect = 0.018 Identities = 23/50 (46%), Positives = 26/50 (52%), Gaps = 8/50 (16%) Query: 76 TTVDVGQVIIAVDVAPGSGD---AAPAPE--PAAQP--EPEPEAPKGRQP 118 TTVDV QVI D+ PGS + A P PE PA P P P G +P Sbjct: 303 TTVDV-QVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRP 351
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 67.2 bits (164), Expect = 3e-15 Identities = 25/116 (21%), Positives = 48/116 (41%), Gaps = 2/116 (1%) Query: 6 KITVFLLDDHEVVRRGVHELLSVEDDIEVVGEAATAADALVRIPATRPDVAVLDVRLPDG 65 T+ + DD +R +++ LS V + AA I A D+ V DV +PD Sbjct: 3 GATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 66 SGVEVCREVRSRDENIKCLMLTSYADDEALFDAIMAGASGYVLKAIRGNELLNAVR 121 + ++ ++ ++ L++++ A GA Y+ K EL+ + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF07132#Harpin protein (HrpN) Length = 356 Score = 34.3 bits (78), Expect = 0.001 Identities = 21/62 (33%), Positives = 25/62 (40%) Query: 470 GGSTDAGTGTADGGSGTADGGTGAADGGSGTADGGTGAADGGTGAADGGAGGAATGATTG 529 G G G GG G++ GG G G G G + G G+A GG G A GA Sbjct: 62 GSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGAGMN 121 Query: 530 TS 531 Sbjct: 122 AM 123
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.4 bits (73), Expect = 0.006 Identities = 43/167 (25%), Positives = 74/167 (44%), Gaps = 34/167 (20%) Query: 79 QHTNIVSVFDTGEDELGGALMPY-------IVMEYVEGQPLGSVLQ--ADIRNYGAMPAD 129 +H N+ +V G A++PY ++M+ V+G L+ AD G + ++ Sbjct: 189 KHPNLANVH-------GMAVVPYGNRKEEALLMDEVDGWRCSDTLRTLADSWKQGKINSE 241 Query: 130 R---ALKVTADVLAALDTSHEM---GLVHRDIKPGNVMVTK-RGVVKVMDFGIARAMQSG 182 +K A L LD ++ + G+VH DIKPGNV+ + G V+D G+ Sbjct: 242 AYWGTIKFIAHRL--LDVTNHLAKAGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQ 299 Query: 183 VTSMTQTGMVVGTPQYLSPEQALGR-GVDARSDLYSVGIMLFQLLTG 228 T++ + +PE +G G +SD++ V L + G Sbjct: 300 PKGFTES--------FKAPELGVGNLGASEKSDVFLVVSTLLHCIEG 338
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 33.6 bits (77), Expect = 0.001 Identities = 51/273 (18%), Positives = 84/273 (30%), Gaps = 67/273 (24%) Query: 211 ETYPPGSTFKVVTAAAALENGLYTGID-----EPTKSPLPYRLPLTTGNLENEGNIPCEN 265 E +P STFKVV A L + L P++ +L + + Sbjct: 60 ERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTV---- 115 Query: 266 ASLRDA-LRVSCNTVFGKISDDLGNQKMIDQANKFGFNKEIFTPVRADASVYPKDNRPQN 324 L A + +S N+ + +G + F ++I D + Sbjct: 116 GELCAAAITMSDNSAANLLLATVGGPAGLTA-----FLRQI-----GDNVTRLDRWETEL 165 Query: 325 AMAGIGQASNRATPLQMAMVAAAVANDGKLMQPYMVAERKAPNLDVIYTHEKEQLSQPLS 384 A G A + TP MA + SQ LS Sbjct: 166 NEALPGDARDTTTPASMAATLRKLL-----------------------------TSQRLS 196 Query: 385 GENAQKLQQMMETVVKNGTGQ---RAKIP-GVTIGGKTGTAQHGLNNSEKPYAWFISYAK 440 + ++L Q M V + R+ +P G I KTG + G ++ Sbjct: 197 ARSQRQLLQWM---VDDRVAGPLIRSVLPAGWFIADKTGAGERGARGI-------VALLG 246 Query: 441 TDSGSPVAVAVVVEDGQA----NRDDISGGGLA 469 ++ + V + + D A I+G G A Sbjct: 247 PNNKAERIVVIYLRDTPASMAERNQQIAGIGAA 279
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 37.0 bits (85), Expect = 3e-04 Identities = 34/119 (28%), Positives = 55/119 (46%), Gaps = 27/119 (22%) Query: 90 IVMEYVDG----STLRELLHSGR-------------KLLPERTLEMTVGILQALEYSHRA 132 ++M+ VDG TLR L S + K + R L++T + +A Sbjct: 212 LLMDEVDGWRCSDTLRTLADSWKQGKINSEAYWGTIKFIAHRLLDVT-------NHLAKA 264 Query: 133 GIVHRDIKPANVMLTR-TGQVKVMDFGIARAMGDS--GMTMTQTAAVIGTAQYLSPEQA 188 G+VH DIKP NV+ R +G+ V+D G+ G+ G T + A +G + E++ Sbjct: 265 GVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTESFKAPELGVGNLGASEKS 323
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.4 bits (73), Expect = 0.004 Identities = 28/102 (27%), Positives = 39/102 (38%), Gaps = 10/102 (9%) Query: 107 FERDWYGQQT------PAPTSAPTHREQPVAHPFPLDDETVGLRTADTRRLVDRAMTTRQ 160 F RD G T P P P E P A P P E + TR Sbjct: 295 FGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLP---EVSPAENPANNPAPNENPGTR- 350 Query: 161 PNSGPEPELGSASDAESFAESGTGPETADPEPRTGGRAERRR 202 PN P+P+L ++ ++ + GT P++ R GR + R Sbjct: 351 PNPEPDPDLNPDANPDTDGQPGTRPDSPAVPDRPNGRHRKER 392
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.5 bits (61), Expect = 0.042 Identities = 11/54 (20%), Positives = 21/54 (38%), Gaps = 1/54 (1%) Query: 1 MSA-RILVVDNYDSFVFNLVQYLYQLGAECEVLRNDEVTTAHAQDGFDGVLLSP 53 M+ ILV D+ + L Q L + G + + N G ++++ Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTD 54
>PF07675#Cleaved Adhesin Length = 1358 Score = 28.1 bits (62), Expect = 0.048 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Query: 111 LTGRSVA--VTLDDAPPNATANPGYPDPQPND-LVIHQQDLQAVVNALWQ 157 LTG +V VTL + PN T NP P+P PN + + + A W+ Sbjct: 598 LTGSAVGQKVTLKWSAPNGTPNPN-PNPNPNPGTTTLSESFENGIPASWK 646
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 39.4 bits (92), Expect = 8e-05 Identities = 14/81 (17%), Positives = 29/81 (35%), Gaps = 2/81 (2%) Query: 1224 PRVLLIEEHEEIALALTETLERRGMQVARASTDNEAVALATRMRPNLVVMDLMQVRRRRA 1283 +L+ ++ I L + L R G V S +LVV D++ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 1284 GIVDWLRANGQLNRTPLVVYT 1304 ++ ++ P++V + Sbjct: 64 DLLPRIKKARP--DLPVLVMS 82
>SSBTLNINHBTR#Streptomyces subtilisin inhibitor signature. Length = 144 Score = 36.4 bits (83), Expect = 1e-05 Identities = 42/128 (32%), Positives = 53/128 (41%), Gaps = 20/128 (15%) Query: 5 LALTAIA---SLAALSAAAPAATAATGPLPLPLPLPLLHADDAGTRLTVTVSGTGDPAAE 61 L LTA A LA S A+PA A+ P L L + H + A T + Sbjct: 11 LGLTATAVCGPLAGASLASPATAPASLYAPSALVLTVGHGESAATAAPLRAV-------- 62 Query: 62 GVFELKCGPAG-GSHPAAQQACDRLEELAGEGADPFA-PVPGDAMCTQQFGGPATARVTG 119 L C P G+HPAA AC EL DP A MCT+++ P V G Sbjct: 63 ---TLTCAPTASGTHPAAAAAC---AELRAAHGDPSALAAEDSVMCTREYA-PVVVTVDG 115 Query: 120 TWRGRGID 127 W+GR + Sbjct: 116 VWQGRRLS 123
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 94.1 bits (234), Expect = 2e-24 Identities = 35/112 (31%), Positives = 61/112 (54%) Query: 22 RVLVVDDEAPLAELLSMALRYEGWEVRSAGDGAGAVRMARDFRPDAVILDVMLPDTDGFA 81 +LV DD+A + +L+ AL G++VR + A R D V+ DV++PD + F Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 82 VLGRLRRELSEVPVLFLTARDAVEDRIAGLTAGGDDYVTKPFSLEEVVARLR 133 +L R+++ ++PVL ++A++ I G DY+ KPF L E++ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 31.4 bits (71), Expect = 0.007 Identities = 25/131 (19%), Positives = 40/131 (30%), Gaps = 27/131 (20%) Query: 361 HWRLELPDEPATVYGDPTRLHQVLVNLLANARTH--TPPGTTVTVRVRATAGHPWVTLEV 418 + ++ V P L Q LV N H + ++ T + VTLEV Sbjct: 241 QFENQINPAIMDVQ-VPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 419 QDDGPGIPPRLLPHVFERFARGDASRSRHAGSTGLGLAIVHAVIAAHGG---RVGVASVP 475 ++ G STG GL V + G ++ ++ Sbjct: 297 ENTGSLALKNT------------------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQ 338 Query: 476 GHTVFAVHLPA 486 G V +P Sbjct: 339 GKVNAMVLIPG 349
>cloacin#Cloacin signature. Length = 551 Score = 45.5 bits (107), Expect = 7e-07 Identities = 33/145 (22%), Positives = 49/145 (33%), Gaps = 4/145 (2%) Query: 504 GHRGSIATAGPS--GASSMGGPGGGGRGGPGGMGGGMRPPGQGNQQGGGMGQPPTGAQGG 561 GH + + G + G GGG G G P G G+ G G GG Sbjct: 8 GHNTGAHSTSGNINGGPTGLGVGGGASDGSG-WSSENNPWGGGSGSGIHWGGGSGHGNGG 66 Query: 562 NQQNGRQPGAMPGTGTAPGTAPG-GTGEDGTPGGGGMGGLLNGSSVSAEAEKLLEKNAGD 620 N G +A G TPG GG+ ++ ++SA ++ G Sbjct: 67 GNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMAALKGP 126 Query: 621 YTWAAAAIGSQNAASYQLATGDPVM 645 + + + Q+A DP M Sbjct: 127 FKFGLWGVALYGVLPSQIAKDDPNM 151
>cdtoxinb#Cytolethal distending toxin B signature. Length = 269 Score = 34.2 bits (78), Expect = 4e-04 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 10/86 (11%) Query: 201 PGRQKVRQILLGDFNAAPAAPELAPLWEELTDIEPGGPTYPAQDPVQRIDYVAVSKDSVR 260 P Q + ++LGDFN PA E+ E P Q + +DY AV+ +SV Sbjct: 180 PVHQALNWMILGDFNREPADLEMNLTVPVRRASEIISPAAATQTSQRTLDY-AVAGNSVA 238 Query: 261 VRDAAVAETL---------ASDHRPV 277 R + + + +SDH PV Sbjct: 239 FRPSPLQAGIVYGARRTQISSDHFPV 264
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 159 bits (404), Expect = 1e-45 Identities = 88/408 (21%), Positives = 176/408 (43%), Gaps = 15/408 (3%) Query: 22 ILGVICLAQLTVLLDNTVLNVAIPSLTQELDASTADVQWMINAYSLVQSGLLLTAGSSAD 81 IL +C+ +L+ VLNV++P + + + A W+ A+ L S G +D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 82 RYGRKKMLVAGLALFGIGSLVAGLAQSSTQ-LIAARAGMGIGGALLMTTTLAVVVQIFDD 140 + G K++L+ G+ + GS++ + S LI AR G G A + VV + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPK 134 Query: 141 SERVKAIGIWSTVSSLGFAVGPLIGGVMLDHFWWGAIFLINIPVAVIGLVAVVRLVPESK 200 R KA G+ ++ ++G VGP IGG++ + W +L+ IP+ I V + + + + Sbjct: 135 ENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKE 192 Query: 201 NPSGERPDLLGALLSTIGMASVVYAIISGPEHGWTSGRVLLTAFIGVAVLIGFVLWELHI 260 D+ G +L ++G+ + S + + ++ + FV + Sbjct: 193 VRIKGHFDIKGIILMSVGIVFFMLFTTS---YSISF-LIVSVLSFLI-----FVKHIRKV 243 Query: 261 PYPMLDMHFFRNQKFIGAVAGAILVAFGMGGSLFLLTQQLQFVVGYGPLEAGLRTA-PLA 319 P +D +N F+ V ++ + G + ++ ++ V E G P Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 320 LSVVALNLTGLGARLVPKLGTPVTIAAGMSLLAAGLAAIALLGGDGYGGMLLGLVVMGAG 379 +SV+ +G LV + G + G++ L+ + L M + +V + G Sbjct: 304 MSVIIFGY--IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGG 361 Query: 380 IALAMPAMANAIMSAIPPEKAGVGAGVNGTLAEFGNGLGVAILGAVLN 427 ++ ++ + S++ ++AG G + + G G+AI+G +L+ Sbjct: 362 LSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 74.6 bits (183), Expect = 3e-18 Identities = 49/221 (22%), Positives = 88/221 (39%), Gaps = 24/221 (10%) Query: 33 AGLDRDRITAASVRLLDAEGLAKFSMRRLAAELDVTAMSLYWYVDTKDDLLE-LALDSV- 90 A L+R+ + A++ LL+ G+ + R+LA +L + +LYW+V K LL+ LA++ + Sbjct: 2 ARLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILA 61 Query: 91 -YSEIAPPREDAHWHDRLRELAVSYRELLVRHGWVSPLAGHFLNMGPHSMLFSHAMQDVV 149 + + + P W LR A+S+R L+R+ + + + Sbjct: 62 RHHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLG-TRPDEKQYDTVETQLRFM 120 Query: 150 RATGLPLHQQTGALSAVFQFVYGFGTIEAHFVQRSAESGVSQDEFFQQALGTIRSQPQLS 209 G L A+SAV F G + + + DE L Sbjct: 121 TENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAPDE-------------NLP 167 Query: 210 RIVESSQNLMDARGGDTVEEMRDRDFTFALDLLIAGIEAMR 250 ++ + +MD+ G ++ F L+ LI G E Sbjct: 168 PLLREALQIMDSDDG-------EQAFLHGLESLIRGFEVQL 201
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 134 bits (339), Expect = 1e-35 Identities = 91/423 (21%), Positives = 176/423 (41%), Gaps = 21/423 (4%) Query: 24 SGAPMTHRQIMEALAGLMLGMFVAILSSTVVSNALPEIISDLGGGQSAYTWVVTASLLAM 83 S + + H QI+ L L F ++L+ V++ +LP+I +D ++ WV TA +L Sbjct: 6 SQSNLRHNQILIWLCILS---FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTF 62 Query: 84 TATTPLWGKLSDLFSKKLLVQIALVIYVAGSVVAGMSTSS-GMLIACRVVQGIGVGGLSA 142 + T ++GKLSD K L+ ++I GSV+ + S +LI R +QG G A Sbjct: 63 SIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPA 122 Query: 143 LAQIVMAAMIAPRERGRYSGYLGAVFAVATVGGPLLGGVITDTSWMGWRWCFYVGVPFAI 202 L +V+A I RG+ G +G++ A+ GP +GG+I W + + +P Sbjct: 123 LVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY----IHWSYLLLIPMIT 178 Query: 203 VALVVLQKTLKLPVVKREVKVDWWGALFISAAVSLLLVWVTFAGDKYDWLSWQTGVMLAG 262 + V L V+ + D G + +S + +++ T Y L Sbjct: 179 IITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTT----SYSIS------FLIV 228 Query: 263 SLILTLLFVFIESRASEPIIPLRLFRNRTITLTSLASLFVGIAMFAGTVFFSQYFQLARG 322 S++ L+FV + ++P + L +N + L + + + Sbjct: 229 SVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQ 288 Query: 323 KSPTMSG-VMTIPMIAGLFVSSTVSGQIITRTGRWKAWLVSGGFLVTAGLGLLGTIRYDT 381 S G V+ P + + + G ++ R G + FL + L + T Sbjct: 289 LSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLT-ASFLLETT 347 Query: 382 EYWHIAVFMAVMGLGIGMMMQNLVLAAQNQVAPADLGSASSVVTFFRSLGGAIGVSALGA 441 ++ + + V+G G+ + + + + G+ S++ F L G++ +G Sbjct: 348 SWFMTIIIVFVLG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 442 VMA 444 +++ Sbjct: 407 LLS 409
>cloacin#Cloacin signature. Length = 551 Score = 33.9 bits (77), Expect = 5e-04 Identities = 30/88 (34%), Positives = 36/88 (40%), Gaps = 10/88 (11%) Query: 47 AGAGPEGAPSGAVAPSGKVTLVPLDRGGKGGGSAGDRADGSGPSPAASAAGDGSGGTSTA 106 +G G +GA + SG + P G GG S DGSG S + G GSG Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGAS-----DGSGWSSENNPWGGGSGSGIHW 56 Query: 107 SGAAGRPRGTTGPGAVGAGSGTGSSGGG 134 G +G G G SG GS GG Sbjct: 57 GGGSGH-----GNGGGNGNSGGGSGTGG 79
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 28.2 bits (63), Expect = 0.011 Identities = 12/70 (17%), Positives = 22/70 (31%), Gaps = 6/70 (8%) Query: 14 LWFFLWIMWLFLLFKVISDIFRSDDLGGW-GKAGWLIVALVLPYLGVLVYVIVRGK---- 68 +W + + LL I L G + +I + + + Y + Sbjct: 154 IWIIIKGNLVTLLQLPTCGIECITPLLGQILRQLMVICTVGFVVISIADYAFEYYQYIKE 213 Query: 69 -SMGKRDIKE 77 M K +IK Sbjct: 214 LKMSKDEIKR 223
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.012 Identities = 24/168 (14%), Positives = 51/168 (30%), Gaps = 9/168 (5%) Query: 166 NLAAPHAAAVASQARIAEAKA-DQEASQREQ-QAAALKAEYERDTAIKRAGFLAETEQYN 223 A ++ + E A + A RE + A + T E Sbjct: 1038 ETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQT 1097 Query: 224 ARAAQAGPLAQARASQEVIEEQTSLAERQAALAAQRLEAEVRRPADAEAYRQRTLAEAAR 283 + + + ++ E+ + + + ++ ++ ++E +P AE R+ + Sbjct: 1098 TETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQ-AEPARENDPTVNIK 1156 Query: 284 DRVKFEADGSAYTERTLAQAQADANSVRATSLRDGNQELIAANRIVEN 331 E T Q A S + + N +VEN Sbjct: 1157 -----EPQSQTNTTADTEQP-AKETSSNVEQPVTESTTVNTGNSVVEN 1198
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 43.9 bits (103), Expect = 9e-07 Identities = 31/152 (20%), Positives = 54/152 (35%), Gaps = 7/152 (4%) Query: 135 SDNLPDAKSLPGVGSLFSGE-SEADKSAAAAAAAPLTTAGLTTAEAEQGATDAGETLRA- 192 D P P S + +E K + A TTA+ + A +A ++A Sbjct: 1020 VDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKAN 1079 Query: 193 ----RILQQAEQQQDAAAAEAKAAQEKAAAEKAAAEAKKQQDAAEAKA-AAEKKKAEEEA 247 + Q + ++ E K EKA E +K Q+ + + + K++ E Sbjct: 1080 TQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETV 1139 Query: 248 KAKAEALRLAKLAASYAIPTSSYTITSTFGQA 279 + +AE R + P S T+ Q Sbjct: 1140 QPQAEPARENDPTVNIKEPQSQTNTTADTEQP 1171
>PERTACTIN#Pertactin signature. Length = 922 Score = 35.8 bits (82), Expect = 4e-04 Identities = 43/160 (26%), Positives = 57/160 (35%), Gaps = 16/160 (10%) Query: 339 TPAEPLALSSMRARGMARDAARHRHTLAARENWASPYGPGSAPPYGPGSAPPYGPRSAPP 398 TP A ++ + D +R+ LAA N APP P+ AP Sbjct: 526 TPRGSAATFTLANKDGKVDIGTYRYRLAANGNGQWSLVGAKAPP---------APKPAPQ 576 Query: 399 YGPRSAPPYGPAYAPPYGPAYAPPYGPGHGPGFASPGQHASPRHGPSAQVTAHAKAQAKA 458 GP+ P PP P PP P P +P P G A+A Sbjct: 577 PGPQPGPQPPQPPQPPQPP--QPPQPPQRQPEAPAP----QPPAGRELSAAANAAVNTGG 630 Query: 459 HGRAAARAVAEYESFATSLASLRRQARRGAA-GPDFAERE 497 G A+ AE + + L LR G A G FA+R+ Sbjct: 631 VGLASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQ 670
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.020 Identities = 9/36 (25%), Positives = 16/36 (44%), Gaps = 6/36 (16%) Query: 520 LVANSLKHGTPPM------RLGLRRTDRRLIIEVTD 549 LV N +KHG + L + + + +EV + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVEN 298
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.4 bits (123), Expect = 3e-09 Identities = 61/278 (21%), Positives = 106/278 (38%), Gaps = 10/278 (3%) Query: 13 ALSAFGLGFTVPYLYVYVAQV--RDLGAGTAGVVLAVFAMAALAVLPFTGRAIDRRGPLP 70 AL A G+G +P L + + + G++LA++A+ A P G DR G P Sbjct: 15 ALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 71 VLVVASAVASLGAAALGLSSGVTASVLSAAVLGAGTAVMQPALATMLVWCSSTATRTRAF 130 VL+V+ A A++ A + + + + V G A A A + + R R F Sbjct: 75 VLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYI-ADITDGDERARHF 133 Query: 131 AMQFFLQNLGLGIGGLVGGQIVDTSRPETFTLLFLIEAAMFVVLGVVACTVRLSRTPSFS 190 G+ G ++GG + S F AA+ + + C + Sbjct: 134 GFMSACFGFGMVAGPVLGGLMGGFSP----HAPFFAAAALNGLNFLTGCFLLPESHKGER 189 Query: 191 DVRPTDGSEAPGGLRALLSHRAMVQLCVLGFVLFFACYGQFESGL-AAYGTEAAGIQPST 249 + R + L + F++ GQ + L +G + +T Sbjct: 190 RPLRREALNPLASFRWARGMTVVAALMAVFFIMQL--VGQVPAALWVIFGEDRFHWDATT 247 Query: 250 LGIALAANTAVIVVAQFVVLRLVERRRRSRVIAWVGLI 287 +GI+LAA + +AQ ++ V R R +G+I Sbjct: 248 IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMI 285
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.8 bits (145), Expect = 9e-13 Identities = 25/115 (21%), Positives = 43/115 (37%), Gaps = 2/115 (1%) Query: 2 TTVLIADDQPMQRFGFRMLLESQDDMTVVGEAANGHEALSLVSRHHPDVALMDIRMPLLD 61 T+L+ADD R L + +N ++ D+ + D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 62 GIEATRRIIRAGARTRVLIVTTFDLDRYAYDGLRAGASGFLIKDALPEELLSGIR 116 + RI +A VL+++ + A GA +L K EL+ I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 33.3 bits (76), Expect = 0.001 Identities = 64/359 (17%), Positives = 114/359 (31%), Gaps = 68/359 (18%) Query: 37 LVLLMSVAFSAPLLWRRTHPLAVLAFMTPFSLANVWTGAIVQAAYLQEIAVFNIALRLPM 96 + LM + + + M L V +V V N ++ + Sbjct: 47 AISLMGLVLTHAYRSFIKRQGWLKLNMGQIILR-VLPACVVIGMV---WFVANTSIWRLL 102 Query: 97 RALAWAGAAVTAPLVVGMLRFPHGWDVLFVPHLWAFALVSLLGIVVRTRKEYTEALVDRA 156 + A T PL + ++ ++V+ V +W SLL K Y +A Sbjct: 103 AFINTKPVAFTLPLALSII-----FNVVVVTFMW-----SLLYFGWHFFKNYKQA----- 147 Query: 157 HRLELERDQQARLAAAAERTRIAREMHDIIGH----NLSVITGLADGGAYAAAKSPDRAA 212 Q ++A+ A+ ++ I H L+ I L + P +A Sbjct: 148 ------EIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRALI-------LEDPTKAR 194 Query: 213 QALEAIGTTSRQALTELRRLLGVLRDHPAEADRTPQPTLDDIDTLLT--GVRAAG-LPVH 269 + L ++ R +L L D L +D+ L ++ L Sbjct: 195 EMLTSLSELMRYSLRYSNARQVSLADE-----------LTVVDSYLQLASIQFEDRLQFE 243 Query: 270 LHIRGRPPSYPPTAGRQLTVYRVVQEALTNTLKHGGTHPSLTAEVTLTYRATE--LEALI 327 I P +VQ + N +KHG ++ L + + Sbjct: 244 NQI-------NPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEV 296 Query: 328 TDTGTTGAE--PEGSGQGITGMRERASLYDGTLEAGPLLPKAIATDSAAGGWRVRLRLP 384 +TG+ + E +G G+ +RER + GT EA I G + +P Sbjct: 297 ENTGSLALKNTKESTGTGLQNVRERLQMLYGT-EAQ------IKLSEKQGKVNAMVLIP 348
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.4 bits (76), Expect = 2e-04 Identities = 16/78 (20%), Positives = 30/78 (38%), Gaps = 4/78 (5%) Query: 101 AHVVGVFVRPEARGEGLAEELFRAGADWAWSLVEPRIERVRLYVHEDNARAAVLYRRIGF 160 A + + V + R +G+ L +WA E + L + N A Y + F Sbjct: 90 ALIEDIAVAKDYRKKGVGTALLHKAIEWA---KENHFCGLMLETQDINISACHFYAKHHF 146 Query: 161 VATG-ESVPVPGDPSARE 177 + +++ P+A E Sbjct: 147 IIGAVDTMLYSNFPTANE 164
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 43.4 bits (102), Expect = 9e-07 Identities = 22/91 (24%), Positives = 30/91 (32%), Gaps = 2/91 (2%) Query: 138 PSQRQEPRPDAQNPQQTEPQPTPEPEPRPTAHSPEAVPTPAPAPAPAPAPVEHTPPE--P 195 P Q +P P+ + EP+P PEP + P P P P P E + P Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKP 116 Query: 196 ALPSPRTPLVVYGPAATRRPAVIQAVQEADG 226 P +P PA A + Sbjct: 117 VESRPASPFENTAPARLTSSTATAATSKPVT 147 Score = 34.2 bits (78), Expect = 9e-04 Identities = 20/90 (22%), Positives = 28/90 (31%), Gaps = 2/90 (2%) Query: 150 NPQQTEPQPTPEPEPRPTAHSPEAVPTPAPAPAPAPAPVEHTPPEPALPSPRTPLVVYGP 209 P EP +P P P P AP +E P+P V P Sbjct: 51 TPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110 Query: 210 AATRRPAVIQ--AVQEADGPALVVTSDPTV 237 +P + + E PA + +S T Sbjct: 111 KRDVKPVESRPASPFENTAPARLTSSTATA 140 Score = 30.0 bits (67), Expect = 0.017 Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 136 PVPSQRQEPRPDAQNPQQTEPQPTPEPEPRPTAHSPEAVPTPAPAPAPAPAPVEHTPPEP 195 PV EP P + P++ P +P+P+P P+ V P PVE P P Sbjct: 67 PVVEPEPEPEPIPEPPKE-APVVIEKPKPKPKP-KPKPVKKVQEQPKRDVKPVESRPASP 124 Query: 196 A 196 Sbjct: 125 F 125
>cloacin#Cloacin signature. Length = 551 Score = 38.9 bits (90), Expect = 3e-05 Identities = 26/79 (32%), Positives = 32/79 (40%) Query: 363 SGDSGSGGARPANAVSGGVAAHSSRNSGGGSGVGGGSVPSAAPPPRSGSGPTSGTPHGSR 422 SG G G A++ SG + + GG G S P GSG GS Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 423 SPRGGGSGSSGNNSTGGGG 441 GGG+G+SG S GG Sbjct: 62 HGNGGGNGNSGGGSGTGGN 80 Score = 29.7 bits (66), Expect = 0.029 Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 4/54 (7%) Query: 356 SSRSGQNSGDSGSGGARPANAVSGGVAAH----SSRNSGGGSGVGGGSVPSAAP 405 S SG +S ++ GG + GG + H + NSGGGSG GG AAP Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAP 87
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 29.7 bits (66), Expect = 0.013 Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 5/54 (9%) Query: 81 GSGGGSGNGGSKPDSSSTAATGTKPVTGKNGSIPSGFAHDEQGAQSAASNFAVA 134 GSGGG G GGSK +SS+ K T + + EQ A++ A+ A A Sbjct: 33 GSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQA-----EQAARAKAAAEAQA 81
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 42.7 bits (100), Expect = 2e-06 Identities = 23/108 (21%), Positives = 29/108 (26%), Gaps = 8/108 (7%) Query: 214 PAADPSADPSDPAATEPP-------APNDSTEPPAEVIPSDPASPSPSDTATVEPIPPVS 266 PA S PA EPP P EP E IP P +P +P P Sbjct: 46 PAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPK-EAPVVIEKPKPKPKPK 104 Query: 267 PSPSAPASSSPAATLPPAPPSTVPKPPITSRAGWGADESMSPEAPEYT 314 P P P P + + + P + Sbjct: 105 PKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTS 152 Score = 40.3 bits (94), Expect = 1e-05 Identities = 23/132 (17%), Positives = 32/132 (24%), Gaps = 11/132 (8%) Query: 219 SADPSDPAATEPPAPNDSTEPPAEVIPSDPASPSPSDTATVEPIPPVSPSPSAPASSSPA 278 P+ P + AP D P A P P EP P P P A Sbjct: 43 LPAPAQPISVTMVAPADLEPPQA-------VQPPPEPVVEPEPEPEPIPEPPKEAPVVIE 95 Query: 279 ATLPPAPPSTVPKPPITSRAGWGADESMSPEAPEYTDTVKAVFVHHTAGTSN----YSCA 334 P P P + P +P ++ + Sbjct: 96 KPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVAS 155 Query: 335 DSAAIVRSVYAY 346 A+ R+ Y Sbjct: 156 GPRALSRNQPQY 167 Score = 31.9 bits (72), Expect = 0.008 Identities = 11/91 (12%), Positives = 23/91 (25%), Gaps = 1/91 (1%) Query: 210 AADIPAADPSADPSDPAATEPPAPNDSTEPPAEVIPSDPASPSPSDTATVEPIPPVSPSP 269 + +P +P P + P P V+P+ SP Sbjct: 70 PEPVVEPEPEPEPI-PEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASP 128 Query: 270 SAPASSSPAATLPPAPPSTVPKPPITSRAGW 300 + + + ++ P + S Sbjct: 129 FENTAPARPTSSTATAATSKPVTSVASGPRA 159
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 66.1 bits (161), Expect = 9e-15 Identities = 57/208 (27%), Positives = 95/208 (45%), Gaps = 13/208 (6%) Query: 87 GGVPYLDFLAPGIIAQSAMFIAIFYGIMIIWER--DSGVLTKLMVTPTPRTALVTGKAFA 144 GGV Y FLA G++A SAM A F I + R ++ T +V G+ Sbjct: 61 GGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAW 120 Query: 145 AGVKAVIQAAVVIVIAALIGVGMTWNPLRLLGVVVVVLLASAFFSCLSMSIAGIVLTRDR 204 A KA + A + V+AA +G + L L V+ + LA F+ L M + + + D Sbjct: 121 AATKAALAGAGIGVVAAALGYTQWLSLLYALPVIALTGLA---FASLGMVVTALAPSYDY 177 Query: 205 LMGIGQAITMPLFFASNALYPVALMPGWLQAISKVNPLSYEVDALRGLLIGTQA-----H 259 + + P+ F S A++PV +P Q ++ PLS+ +D +R +++G H Sbjct: 178 FIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDVCQH 237 Query: 260 LGLDLAVLAFAALAGIVAAGSLLGRLAR 287 +G A+ + + ++ L RL R Sbjct: 238 VG---ALCIYIVIPFFLSTALLRRRLLR 262
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 43.8 bits (103), Expect = 2e-07 Identities = 17/91 (18%), Positives = 34/91 (37%), Gaps = 3/91 (3%) Query: 19 GRVDEAKAMLAKRLAQDPEDVRAWSQLGRCHEQLKEYEQAVEATGAALAIDPEYVNALII 78 G+ ++A + D D R + LG C + + +Y+ A+ + +D + Sbjct: 50 GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFH 109 Query: 79 RTYALRRLRRTDES---LAAAQEAVRLAPHY 106 L + E+ L AQE + + Sbjct: 110 AAECLLQKGELAEAESGLFLAQELIADKTEF 140
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.031 Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 14/82 (17%) Query: 42 VAEAAVALQHAPGDAAARALMMRA-MGLPAPADDKAEKAEEPPKAEEPEQPAAHRPSTGF 100 V++AA + G + ++M A G PAP +PP+ E P +P + Sbjct: 86 VSKAAAQVAREEGLESVAGIVMGAPAGAPAP---------KPPRPEPPPRPVVEKEC--- 133 Query: 101 DWAAAENEVAGAVPPRFVAPAP 122 W + AVPP F PAP Sbjct: 134 -WETIQPVPEHAVPPSFWHPAP 154
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 51.3 bits (123), Expect = 8e-10 Identities = 53/269 (19%), Positives = 96/269 (35%), Gaps = 32/269 (11%) Query: 1 MHALDIDSGAQL-GVEADQLVCTASVHKLCLLVALYDRAAAGDLDLTEQVECSSDPRTPG 59 M +D+ SG L AD+ S K+ L A+ R AGD L ++ Sbjct: 42 MIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDY 101 Query: 60 PTGLAAMLDAARLSLRDLAYLMMAVSDNAAADLLLARI-GLDAVNGATARLGLDATRAVH 118 L +++ +L + +SDN+AA+LLLA + G + ++G + TR Sbjct: 102 SPVSEKHLADG-MTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDR 160 Query: 119 TFGAMLASVKEDAGPAGAQALADPHVVARLRALDPARSNRSTPRDMTRLLRAVWRDEACL 178 + ++ DA + +TP M LR + + Sbjct: 161 WETELNEALPGDA------------------------RDTTTPASMAATLRKLLTSQRLS 196 Query: 179 PEHGAAIRRVM-GLQVWPHRLASGFPFDDVLVAGKTGSLPT-LRNEVGVVEYPDGGRYAV 236 + + M +V + S P +A KTG+ R V ++ + V Sbjct: 197 ARSQRQLLQWMVDDRVAGPLIRSVLP-AGWFIADKTGAGERGARGIVALLGPNNKAERIV 255 Query: 237 AVFTRTARTAATLPAADAVIGTAARIAVD 265 ++ R T A++ + I ++ Sbjct: 256 VIYLRD--TPASMAERNQQIAGIGAALIE 282
>SECA#SecA protein signature. Length = 901 Score = 24.8 bits (54), Expect = 0.027 Identities = 10/37 (27%), Positives = 18/37 (48%) Query: 22 IELAPVDGSIKMRESDDPDVVVTTTVAKLRAFVLGVK 58 ++ V + M D PD+V T K++A + +K Sbjct: 407 LDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIK 443
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 25.6 bits (56), Expect = 0.037 Identities = 8/26 (30%), Positives = 11/26 (42%), Gaps = 1/26 (3%) Query: 47 GDA-VVTTGAFESQQAFQAAFAAVAR 71 GD V A S Q F +++V Sbjct: 342 GDLQVTIKEADGSTQIFTVPYSSVPL 367
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 2e-08 Identities = 20/78 (25%), Positives = 40/78 (51%) Query: 5 RTPRENWVEEGLRVLASGGVDAVRVEALAKSLGVTKGGFYGYFADRDALLKEMLDTWERE 64 + R++ ++ LR+ + GV + + +AK+ GVT+G Y +F D+ L E+ + E Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 65 ATDDVLDRIEREGGDLMD 82 + L+ + GD + Sbjct: 70 IGELELEYQAKFPGDPLS 87
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.8 bits (74), Expect = 0.005 Identities = 22/52 (42%), Positives = 30/52 (57%), Gaps = 5/52 (9%) Query: 108 AGVVHRDLKPANLMLT-AGGEVKVLDFGIARYMSASAKSSKVMGTLAYMAPE 158 AGVVH D+KP N++ A GE V+D G+ S S + K T ++ APE Sbjct: 264 AGVVHNDIKPGNVVFDRASGEPVVIDLGL---HSRSGEQPKGF-TESFKAPE 311
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 44.4 bits (105), Expect = 4e-07 Identities = 64/354 (18%), Positives = 120/354 (33%), Gaps = 18/354 (5%) Query: 34 IFSIVTTEILPIGL----LTSIGSDFAVSDGTA---GLMMTMPGLLAAVSAPLVTVVTAR 86 I S V + + IGL L + D S+ G+++ + L+ AP++ ++ R Sbjct: 10 ILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDR 69 Query: 87 VDRRVMLCAFMLLLALADFLVAAATDYRLVLVSRVMVGITIGGFWSIGAGLAGRLVRPAS 146 RR +L + A+ ++A A ++ + R++ GIT G ++ + Sbjct: 70 FGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDE 128 Query: 147 VGRATAVIFSAVPLGSVLGVPAGTFIGGLTGWRTAFVAMGVLTMGVLALMLLVIP----- 201 R + + G V G G +GG F A L ++P Sbjct: 129 RARHFGFMSACFGFGMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 202 ---ALPPTQVSRASVLRTVLGRTGTRFALLLTFLIVLSHFATYTYVTPFLEQVTRADPAL 258 L ++ + R G T + + F++ L F E D Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT 247 Query: 259 ITVFLLVYGAAGIVGNFVGGALVTRRPRVAVSLAAGLIATATALLPVLGTGEAGAVALLI 318 I + L +G + + V R +L G+IA T + + ++ Sbjct: 248 IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIM 307 Query: 319 VWGVAYGAVPVCSQTWFAKAAPDAPEAASVLFTASFQA-TFALGALTGGAILDH 371 V + G Q ++ + + A+ + T +G L AI Sbjct: 308 VLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 31.6 bits (71), Expect = 0.003 Identities = 30/134 (22%), Positives = 42/134 (31%), Gaps = 10/134 (7%) Query: 25 GVAGGVLSTIAVAGAAGPAQAEPVTQTIEMPTITAGLSTAVAASAQATEQVAQDLQTQAQ 84 GVA G L+ AG A + A + A+ V L + A Sbjct: 230 GVAAGALNPFISAGEALGIGD--ILYGTRYAIDKAAMRNIAPLPAEGKFAVIGGLGSVAG 287 Query: 85 EDAAAATAAKTAKKAKAEAVRKAEAKKKAEAAAKAKAEAAERASRT-AARTTLSATSGSS 143 + A + A E A A AA+ A AA+ +A SG Sbjct: 288 FEKNTREAVDRWIQENPNAAETVE-------AVFNVAAAAKVAKLAKAAKPGKAAVSGDF 340 Query: 144 AGSAVASASSSSSS 157 A S + S S+ Sbjct: 341 ADSYKKKLALSDSA 354
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 48.7 bits (116), Expect = 5e-09 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 2 RVVIAEDSVLLREGLTRLLTDLGHDVVAGVGDAEALIKTVRDLAGQDALPDVVVADVRMP 61 +++A+D +R L + L+ G+DV +A L + + D+VV DV MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIA-----AGDGDLVVTDVVMP 58 Query: 62 PTHTDEGVRAAVRLRKDYPGIGVLVLSQY 90 + R++K P + VLV+S Sbjct: 59 DEN---AFDLLPRIKKARPDLPVLVMSAQ 84
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 1e-04 Identities = 18/85 (21%), Positives = 32/85 (37%), Gaps = 11/85 (12%) Query: 368 FTVSELLQNVSKHARATRAS-----VDVWRTADRLMLQVTDNGRGGADV---SSGSGLAG 419 V L++N KH A + + + L+V + G S+G+GL Sbjct: 258 MLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQN 317 Query: 420 LTERLDAV---DGVLVVDSPQGGPT 441 + ERL + + + + QG Sbjct: 318 VRERLQMLYGTEAQIKLSEKQGKVN 342
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 34.7 bits (79), Expect = 6e-04 Identities = 42/180 (23%), Positives = 68/180 (37%), Gaps = 45/180 (25%) Query: 108 PWLWSSLTDPVGWRAVLYSFIRLPWGVLTFTVTLVSLFVLWPVLPYIARLLANADRAMAR 167 PW WS++ + + VT++ F P P++ L A + A Sbjct: 255 PWAWSNIDT----------------SKVNYGVTVLPTFKGQPSKPFVGVLSAGINAA--- 295 Query: 168 ALLSPSDELERRIAE--LESDRGVVVDTAAADLRRIERDLHDGAQARLVALAMGLGLAKE 225 SP+ EL + E L +D G L + +D GA A L +E Sbjct: 296 ---SPNKELAKEFLENYLLTDEG---------LEAVNKDKPLGAVA--------LKSYEE 335 Query: 226 KLTDDPEAAARMVDEAHGEVKVALQELRDLARGIHPAVLT----DRGLDAALSAIASRCT 281 +L DP AA M + GE+ + ++ + AV+ + +D AL +R T Sbjct: 336 ELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDEALKDAQTRIT 395
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 32.8 bits (74), Expect = 0.002 Identities = 24/80 (30%), Positives = 28/80 (35%), Gaps = 10/80 (12%) Query: 297 PGSSDAPWHHARPAFDTTGGPQAEPPVREGAGRGEAPRSDTSVPEATPTADTTAPTDTPD 356 PGS++AP P P P E G P D P+ P A+ PD Sbjct: 317 PGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPD---PDLNPDAN-------PD 366 Query: 357 QPEPPAQDPTPEPAPDRPAG 376 P P PDRP G Sbjct: 367 TDGQPGTRPDSPAVPDRPNG 386 Score = 31.6 bits (71), Expect = 0.005 Identities = 21/61 (34%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 312 DTTGGPQAEPPVREGAGRGEAPRSDTSVPEATPTADTTAPTDTPDQPEPPAQDPTPEPAP 371 +TT Q P G EAP + +PE +P + P + P E P P PEP P Sbjct: 302 NTTVDVQVIPRPDLTPGSAEAPNAQ-PLPEVSPAEN---PANNPAPNENPGTRPNPEPDP 357 Query: 372 D 372 D Sbjct: 358 D 358
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.2 bits (148), Expect = 5e-14 Identities = 28/142 (19%), Positives = 60/142 (42%), Gaps = 6/142 (4%) Query: 3 AEERRESVIRAAITEFARGGYAATSTEAIAKRVGVSQPYLFRLFPNKQAMFLAAAERCLA 62 A+E R+ ++ A+ F++ G ++TS IAK GV++ ++ F +K +F E + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 63 DTRKVFSDAAEGLEGDEA---LHAMAAAYQRLIVGDPDKLLMQMQTYAAVAAAEASGDHE 119 + ++ + GD + + + + +LLM++ + E + + Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 120 FGESTRAGWLQMWDEIHLALGA 141 R L+ +D I L Sbjct: 129 AQ---RNLCLESYDRIEQTLKH 147
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 155 bits (393), Expect = 2e-44 Identities = 87/400 (21%), Positives = 162/400 (40%), Gaps = 14/400 (3%) Query: 23 FMAALDNLVVTTALPSIRESLGGELAELEWTVNAYTLTFAVLLMLGAALGDRFGRRRLFL 82 F + L+ +V+ +LP I A W A+ LTF++ + L D+ G +RL L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 83 AGLTVFTGASAAAALSPGINE-LIAFRAVQGVGAAIMMPLTLTLLTAAVPPARRGTALGI 141 G+ + S + LI R +QG GAA L + ++ +P RG A G+ Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 142 FSAITGLAVAGGPLIGGSLTEHLSWQWIFWLNVPIGLVLLPLARLRLTESHAPDSRLDIP 201 +I + GP IGG + ++ W ++ + + I ++ +P L + DI Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPM-ITIITVPFLMKLLKKEVRIKGHFDIK 202 Query: 202 GTLLVSAGLFGIVYGLVNADSDGWTSPTVLTALFAGAALIGGFIHHGFHAKNPMLPMRLF 261 G +L+S G+ + S + V F F+ H +P + L Sbjct: 203 GIILMSVGIVFFMLF---TTSYSISFLIVSVLSF------LIFVKHIRKVTDPFVDPGLG 253 Query: 262 RSRAFFGINMAGLLMFLGMFGSIFLLSQYFQGVLGYSPTEAG-LRMLPWTGMPMLVAPIA 320 ++ F + G ++F + G + ++ + V S E G + + P T ++ I Sbjct: 254 KNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIG 313 Query: 321 GILSDRLGGRPVVVAGLALQAVGLALFAMVIGPDASYSSQLPGLIVGGVGMALYFAPAAG 380 GIL DR G V+ G+ +V + + + + ++ G++ + Sbjct: 314 GILVDRRGPLYVLNIGVTFLSVSFLTASFL--LETTSWFMTIIIVFVLGGLSFTKTVIST 371 Query: 381 LVMSSVRPAEQGIASGANNALREVGGALGVAVLATVFSSQ 420 +V SS++ E G N + G+A++ + S Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIP 411
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.8 bits (62), Expect = 0.032 Identities = 11/30 (36%), Positives = 18/30 (60%) Query: 1 MRITVFGATGGIGREIVRQAVAAGHEVTAV 30 M+ V GA G IG + ++ + AGH+V + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGI 30
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.1 bits (166), Expect = 2e-16 Identities = 33/164 (20%), Positives = 60/164 (36%), Gaps = 2/164 (1%) Query: 2 EQKPARVRIIDAAHQLMLTIGLARATTKEIARAAGCSEAALYKHFPSKEELFVAVLKERL 61 E + R I+D A +L G++ + EIA+AAG + A+Y HF K +LF + + Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 62 PRLNPLLKRLIE-TPGVGERTVEQNLTEIARQAALFYEQSFPIAASLYAEPRLKERHNAA 120 + L PG + + L + + + + + E Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQ 127 Query: 121 MRELGTGPHMPIRGLDAYLRSEQAAGRVRADADTYAAASLLLGA 164 + ++ L+ A + AD T AA ++ G Sbjct: 128 QAQRNLCLES-YDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGY 170
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 34.5 bits (79), Expect = 1e-05 Identities = 15/39 (38%), Positives = 26/39 (66%), Gaps = 1/39 (2%) Query: 41 LFYRQIVAELRKVVWPTRNQLTTYTSVVIVFVVVMIGLV 79 F R+ E+RKV+WPTR Q T +T++++ V ++ L+ Sbjct: 70 AFAREARTEVRKVIWPTR-QETLHTTLIVAAVTAVMSLI 107
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 391 bits (1006), Expect = e-138 Identities = 126/371 (33%), Positives = 178/371 (47%), Gaps = 21/371 (5%) Query: 9 ARAEIDLAALRANVRVLRARAAGAQLMAVVKSDAYGHGAVPCARAALEAGATWLGTATPQ 68 +A +DL AL+ N+ ++R A A++ +VVK++AYGHG A + Sbjct: 5 IQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATD--GFALLNLE 62 Query: 69 EALALRAAGLGGRV-MCWLWTPGGPWREAIEADIDVSVSGMWALREVVAAATEAGIPARV 127 EA+ LR G G + M + + + V W L+ + A +A P + Sbjct: 63 EAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKA--PLDI 120 Query: 128 QLKADTGLGRNGCQPADWPELVAAARAAEDAGTVRITGLWSHFACADEPGHPSIAAQLNL 187 LK ++G+ R G QP ++ + V L SHFA A+ P I+ + Sbjct: 121 YLKVNSGMNRLGFQP---DRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDG--ISGAMAR 175 Query: 188 FRDMVAYAEKEGVDPEVRHIANSPATLTIPEAHFDLVRTGIAMYGISPSPELGTPADFGL 247 E R ++NS ATL PEAHFD VR GI +YG SPS + A+ GL Sbjct: 176 IEQAAEGLECR------RSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGL 229 Query: 248 RPVMRLVASVALVKRVPAGHGVSYGHHYTTSTETTLGLVPVGYADGIPRHASGRAPVLVG 307 RPVM L + + V+ + AG V YG YT E +G+V GYADG PRHA PVLV Sbjct: 230 RPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVD 289 Query: 308 GVRRRIAGRVAMDQFVVDLDGD-ETEVGTEAVLFGPGDRGEPSAEDWAQACDTIAYEIVT 366 GVR G V+MD VDL + +GT L+G E +D A A T+ YE++ Sbjct: 290 GVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGK----EIKIDDVAAAAGTVGYELMC 345 Query: 367 RISSRVPRVHL 377 ++ RVP V + Sbjct: 346 ALALRVPVVTV 356
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 35.2 bits (81), Expect = 3e-04 Identities = 19/114 (16%), Positives = 34/114 (29%), Gaps = 25/114 (21%) Query: 176 QADGV-TVGID------------QLGRDLKAVIDAAAPE---GRLVLVGHSMGGMTMMAL 219 Q G VG + +D A+ID E +++L+G+S G + + Sbjct: 75 QQQGWPVVGWSSLKYYWKQKDPKDVTQDTLAIIDKYQAEFGTQKVILIGYSFGAEVIPFV 134 Query: 220 AEQYPQLIRDRVAAVAFVGTS---------SGKLGEVTFGLPIAGVNAVRRVLP 264 + P R V + S S + + V + Sbjct: 135 LNEMPARYRKNVLGAVLLSPSQSSDFEIHVSEMVTSDNQSARYLTLPEVNKQTT 188
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.5 bits (61), Expect = 0.034 Identities = 14/40 (35%), Positives = 22/40 (55%), Gaps = 1/40 (2%) Query: 28 ESPEQMQALGRRIAGVLRPGDLVMLTGELGAGKTTLTRGL 67 S MQ + R +A +++ +M+TGE G GK + R L Sbjct: 142 RSA-AMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 2e-05 Identities = 17/81 (20%), Positives = 32/81 (39%), Gaps = 1/81 (1%) Query: 64 IVGYAGLAAA-GDLADVQTIGVTRDHWGGGLGSELLSDLLKHATAFECAEVLLEVRVDNT 122 +G + + A ++ I V +D+ G+G+ LL ++ A ++LE + N Sbjct: 76 CIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINI 135 Query: 123 RAQKLYERFGFEPIGFRRGYY 143 A Y + F Y Sbjct: 136 SACHFYAKHHFIIGAVDTMLY 156
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 57.2 bits (138), Expect = 5e-12 Identities = 39/211 (18%), Positives = 77/211 (36%), Gaps = 25/211 (11%) Query: 34 RLDPDAMVATARRIIEEEGLDALSMRRVAKELGSTPMALYHYVQDKDEL---LMLTLSGT 90 RL+ ++++ A ++ E G+D L+ R++A++LG LY +V++K L L + + Sbjct: 3 RLNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILAR 62 Query: 91 AAAFPRPELPEDPRERL------LAVAVHMHGILEQIPWVLDILALGELTDRNALWMVEE 144 + P E + L A+ + ++ LG D VE Sbjct: 63 HHDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKV-------HLGTRPDEKQYDTVET 115 Query: 145 IIGSALACGLSPTRAVRAYRTIWSYVYGDLVFRRAAERRAENPPSRPYFPEMITEEDAAA 204 + G S + A + + G ++ ++ + P+ P D Sbjct: 116 QLRFMTENGFSLRDGLYAISAVSHFTLGAVLEQQEHTAALTDRPAAP---------DENL 166 Query: 205 LPRLTEIKDRWREYAADYEVAEELDAIIEGL 235 P L E + L+++I G Sbjct: 167 PPLLREALQIMDSDDGEQAFLHGLESLIRGF 197
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 129 bits (326), Expect = 7e-35 Identities = 93/406 (22%), Positives = 162/406 (39%), Gaps = 20/406 (4%) Query: 11 LLVVALVVQFMVALDMSVVNVALPDMRRDLGFTPEGLLWVVNAYALAFGGLLMLGGRLAD 70 +L+ ++ F L+ V+NV+LPD+ D P WV A+ L F + G+L+D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 71 LIGGSRVLTAGLVLFGAASLAGGLAWSPGG-LIAARAAQGIGAAALAPVAFALIAIAFPA 129 +G R+L G+++ S+ G + S LI AR QG GAAA P ++ + Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVARYIP 133 Query: 130 GPARSRALGLWGMAGAAGGAVGVLAGGVLTDAASWRAVMLVNVPIVVFALVGAVRSGLES 189 R +A GL G A G VG GG++ W L+ +P++ V + L Sbjct: 134 KENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMK-LLK 190 Query: 190 RPARTGARLDVAGALLATAGTALLVLGLVRTSTHPWGSARTLSTLGVAVFLLVVFAAVEL 249 + R D+ G +L + G +L T+++ L V+V ++F Sbjct: 191 KEVRIKGHFDIKGIILMSVGIVFFMLF---TTSYSISF------LIVSVLSFLIFVKHIR 241 Query: 250 RAGTPLLRLGLLKGRPVLTANLFCLLLSSGQFAAF-YFASLYMQQVLGYGPTAAGAAFV- 307 + P + GL K P + + C + G A F M+ V G+ + Sbjct: 242 KVTDPFVDPGLGKNIPFMIG-VLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIF 300 Query: 308 PFSVGVVAGSVVATRTVAALGTRRLLAAGGALAALGLAGFAATAQADGSFLYSILGPSLV 367 P ++ V+ + V G +L G ++ + + + + + V Sbjct: 301 PGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL--LETTSWFMTIIIVFV 358 Query: 368 CGAGIGMCFVPLGTAATTGVASDETGMASGLLNSARQVGGSLGLAV 413 G G+ + T ++ + E G LLN + G+A+ Sbjct: 359 LG-GLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAI 403
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 35.3 bits (81), Expect = 5e-04 Identities = 37/177 (20%), Positives = 54/177 (30%), Gaps = 32/177 (18%) Query: 214 GLLYASVEGSPPYDKGSAIATLTAVMTEPLDPPKNAGPLEEVIYGLLARDPDQRLDDAGA 273 GLLY SV + ++T V L+PP+ P E + +P+ Sbjct: 26 GLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPEPV-----VEPE-------- 72 Query: 274 RALLNDVIHAPEKPDPVVLPPADATQIMALPGQAAEPGSKPASKSGESGEGARDRLRGAL 333 PE P I +P KP + RD Sbjct: 73 ----------PEPEPIPEPPKEAPVVI---EKPKPKPKPKPKPVKKVQEQPKRDVKPVES 119 Query: 334 RSARNAKAAPAAAVGAAAASTTAPPLPSTPPSTAPSTGSSKPARPSTPAKPAAASAA 390 R A + A + ++ A+ A P T ++ P S P PA A A Sbjct: 120 RPASPFENTAPARLTSSTAT-AATSKPVTSVASGPRALSRNQ-----PQYPARAQAL 170
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.6 bits (71), Expect = 0.017 Identities = 28/84 (33%), Positives = 34/84 (40%), Gaps = 13/84 (15%) Query: 214 PAYETDPTGPYAPPPAPAPPVAPAEVPAARGPAAIETGRATGDPYDDDDPYDDPHPGDRY 273 P + P AP P P V+PAE P A PA E +P D D D +P Sbjct: 311 PRPDLTPGSAEAPNAQPLPEVSPAENP-ANNPAPNENPGTRPNPEPDPDLNPDANPDT-- 367 Query: 274 ADDPHDGVPGELEAVRPPVNPALP 297 DG PG P +PA+P Sbjct: 368 -----DGQPGT-----RPDSPAVP 381
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 42.0 bits (98), Expect = 6e-06 Identities = 67/252 (26%), Positives = 102/252 (40%), Gaps = 48/252 (19%) Query: 54 VAEADRIVLHARTQKEARAAARI-----THPGVVTVHD--VIEYDDRP--WIVMQYVDG- 103 VA+ +R + E A I HP + VH V+ Y +R ++M VDG Sbjct: 161 VAKIERSIAEGHLFAELEAYKHIYKTAGKHPNLANVHGMAVVPYGNRKEEALLMDEVDGW 220 Query: 104 ------PSLADAAKESGEIEPR----EAARIGLHVLGALRAAHGAGVLHRDVKPGNVLLA 153 +LAD+ K+ G+I I +L AGV+H D+KPGNV+ Sbjct: 221 RCSDTLRTLADSWKQ-GKINSEAYWGTIKFIAHRLLDVTNHLAKAGVVHNDIKPGNVVFD 279 Query: 154 K-DGQVLLTDFGIAAIEGDSTITRTGELVGSIDYLAPERVRGG-DPGPASDLWSLGATLY 211 + G+ ++ D G+ + G+ T + APE G SD++ + +TL Sbjct: 280 RASGEPVVIDLGLHSRSGEQPKGFTES------FKAPELGVGNLGASEKSDVFLVVSTLL 333 Query: 212 TAVEGRSPFRRTSPISTMQAV--VTEEPP-----------PPGRAG---PLASVITALLR 255 +EG F + I Q + +T EP PG AG IT +L Sbjct: 334 HCIEG---FEKNPEIKPNQGLRFITSEPAHVMDENGYPIHRPGIAGVETAYTRFITDILG 390 Query: 256 KDPEDRPSAAEA 267 + RP + EA Sbjct: 391 VSADSRPDSNEA 402
>cloacin#Cloacin signature. Length = 551 Score = 41.2 bits (96), Expect = 9e-06 Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 8/101 (7%) Query: 478 SDNGDGGSGSTASGGASGSGSGSGSAGPATAGGSTTGAGATSNGSTTAGAATGGSTTAGS 537 S N +GG GG + GSG S GGS +G G G S Sbjct: 17 SGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSG 76 Query: 538 TGGSLASTGT--------VALPVAAGAAVALAAGGVLYATA 570 TGG+L++ ++ P A G AV+++AG + A A Sbjct: 77 TGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIA 117 Score = 30.1 bits (67), Expect = 0.030 Identities = 28/90 (31%), Positives = 35/90 (38%), Gaps = 9/90 (10%) Query: 478 SDNGDGGSGSTASGGASGSG----SGSGSAGPATAGGSTTGAGATSNGSTTAGAATGGST 533 SD S + GG SGSG GSG G S G+G N S A G Sbjct: 34 SDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFP 93 Query: 534 TAGSTGGSLASTGTVALPVAAGAAVALAAG 563 + G G +A+ ++AGA A A Sbjct: 94 ALSTPGA-----GGLAVSISAGALSAAIAD 118
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 27.5 bits (61), Expect = 0.027 Identities = 13/43 (30%), Positives = 20/43 (46%), Gaps = 7/43 (16%) Query: 72 SSAIPALVDLAL-------KNPGAFGYAIAIGELAVGIGTLIG 107 ++A PALV + + AFG +I + G+G IG Sbjct: 117 AAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIG 159
>PF06580#Sensor histidine kinase Length = 349 Score = 32.9 bits (75), Expect = 0.002 Identities = 15/80 (18%), Positives = 27/80 (33%), Gaps = 8/80 (10%) Query: 347 NAAKYG----GEGGAVQVYAEVEGRTVFVSVRDRGPGFDLDSVPGDRMG---VRESIIGR 399 N K+G +GG + + + TV + V + G ++ G VRE + Sbjct: 266 NGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQML 325 Query: 400 MQRNGGTARLRSVPGGGTEV 419 +L G + Sbjct: 326 YGTEAQI-KLSEKQGKVNAM 344
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 44.1 bits (104), Expect = 2e-07 Identities = 23/110 (20%), Positives = 42/110 (38%), Gaps = 8/110 (7%) Query: 14 RVRVVLVDDHRMFRTGVQAEIGRTEETGVEVVGEAADVDQAVTVITATRPEVVLLDVHLP 73 +++ DD RT + + R G +V ++ I A ++V+ DV +P Sbjct: 3 GATILVADDDAAIRTVLNQALSRA---GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 74 GGGGVEVLRRCAPLMGAAENPVRFLALSVSDAAEDVIGVIRGGARGYVTK 123 ++L R + A + L +S + I GA Y+ K Sbjct: 59 DENAFDLLPR----IKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPK 104
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 29.1 bits (65), Expect = 0.011 Identities = 14/57 (24%), Positives = 25/57 (43%), Gaps = 3/57 (5%) Query: 190 LAVAAAFRRRGIGAALCAHLTATAFELGCRVVWLEPGDADVERIYAGIGYRRVGEKL 246 +AVA +R++G+G AL A E + LE D ++ + Y + + Sbjct: 95 IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHF---YAKHHFII 148
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 3e-05 Identities = 26/207 (12%), Positives = 52/207 (25%), Gaps = 24/207 (11%) Query: 15 SAARTAATLAIAGAATAAALPGSAHADPQLTPAQVRAEVDRLYHDAEVATEQYNGAKEKA 74 R L Q + + L EQ++ + + Sbjct: 149 EQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIK------EQFSTWQNQK 202 Query: 75 TAAADAVDTLRDEAARRTERLNASRNALGSLAAAQYRTGGLDPAVQLALSSDPDQYLERA 134 +D R E R+N N + R + Q + + Sbjct: 203 YQKELNLDKKRAERLTVLARINRYENLSRVE---KSRLDDFSSLLH-------KQAIAKH 252 Query: 135 SYVDRVGDRQAAEVDG-VERQVARIAQLRSQAGGKLAALASRQAELKKHKATIRTKLADA 193 + +++ + + E + +++ Q+ S+ K I KL Sbjct: 253 AVLEQ--ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN---EILDKLRQT 307 Query: 194 QRLLATLSPAERAAYESSDSAHSAGRA 220 + L+ A S RA Sbjct: 308 TDNIGLLT--LELAKNEERQQASVIRA 332
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 39.7 bits (92), Expect = 2e-05 Identities = 25/161 (15%), Positives = 49/161 (30%), Gaps = 8/161 (4%) Query: 110 AAQYRTGSIAPSTTFFLADDPQSYFDESQLMSRMTGQQQKAVTDFRTQQAKASKKRAEAV 169 + IA + + E+ +Q+ + Q A + + V Sbjct: 1009 SVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREV 1068 Query: 170 QSLETLTSTQTTLRTSKRNVQEKLGEARAMLSKLTA----EEKARLAALERKKE----AE 221 T + E + +K TA EEKA++ + ++ ++ Sbjct: 1069 AKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQ 1128 Query: 222 AKRKAQELARQQAAAEAEADRKAAEAAKETESGSGTGTGTG 262 K ++ Q AE + KE +S + T T Sbjct: 1129 VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTE 1169 Score = 29.6 bits (66), Expect = 0.025 Identities = 38/296 (12%), Positives = 77/296 (26%), Gaps = 36/296 (12%) Query: 10 PRTRVRTTTPAVGLTTAALASVTLLSAQSATAAPAPKPGIEDVQKKVDDLYRQAGTATQQ 69 ++ P+V +A V PAP E + ++ +++ T + Sbjct: 999 TPNNIQADVPSVPSNNEEIARVDEAPVPP----PAPATPSETTETVAENSKQESKTVEKN 1054 Query: 70 YNRAKEA----------------STTQRAKVDALLEDVAERADKLNDARRTLGAYAAAQY 113 A E + TQ +V + E T+ A+ Sbjct: 1055 EQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKV 1114 Query: 114 RTGSIAPSTTFFLADDPQSYFDESQLMSRMTGQQQKAVTDFRTQQAKASKKRAEAVQSLE 173 T P+ E+ ++ + + Q++ + + E Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 174 T------LTSTQTTLRTSKRNVQEKLGEARAMLSKLTAEEKARLAALERKKEAEAKRKAQ 227 T + TT+ T V+ A T + + + K + Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPA-----TTQPTVNSESSNKPKNRHRRSVRS 1229 Query: 228 ELARQQAAAEAEADRKAAEAAKETESGSGTGTGTGTGSDSSATTKAEKALAFAAAQ 283 + A + DR T + + SD+ A + A Sbjct: 1230 VPHNVEPATTSSNDRSTVALCDLTSTNTNAVL-----SDARAKAQFVALNVGKAVS 1280
>LIPPROTEIN48#Mycoplasma P48 major surface lipoprotein signature. Length = 428 Score = 66.6 bits (162), Expect = 3e-14 Identities = 69/319 (21%), Positives = 118/319 (36%), Gaps = 50/319 (15%) Query: 13 VTAALALTATACGESS--------------TESSGSDKGKMKIGMAYDV--------GGR 50 + A L A +CG + T ++ + K +K + G Sbjct: 14 IAAILPAVAVSCGNNDESNISFKEKDISKYTTTNANGKQVVKNAELLKLKPVLITDEGKI 73 Query: 51 GDNSFNDSAARGLDKAKSEFSAETKELTAKNGETPADREQRLESLAEGGYNPVIAVGFAY 110 D SFN SA L + E N E ++ E S G+ + GF + Sbjct: 74 DDKSFNQSAFEALKAINKQTGIE-----INNVEPSSNFESAYNSALSAGHKIWVLNGFKH 128 Query: 111 KDAVDKIAAKY------PKVSFGLVD--SVATAKNVDSIVFTEEQGSYLAGVAAA--LKS 160 + ++ + + ++ +D K S+ F ++ ++ G A A L Sbjct: 129 QQSIKQYIDAHREELERNQIKIIGIDFDIETEYKWFYSLQFNIKESAFTTGYAIASWLSE 188 Query: 161 KDGQ---VGFIGGVDLPLIKKFAAGFQQGVLD-TKPKAKVQIQYLSTGSDLSGFGSPDKG 216 +D V GG P + F GF +G+L + +I + S SGF + +K Sbjct: 189 QDESKRVVASFGGGAFPGVTTFNEGFAKGILYYNQKHKSSKIYHTSPVKLDSGFTAGEKM 248 Query: 217 KEAAKGMLDKGADVIFAAAGG--SGAGSIEAVAGK---KGAWSIGVDSDQALDPALSKYK 271 +L + S AG + KG + IGVDSDQ + + K Sbjct: 249 NTVINNVLSSTPADVKYNPHVILSVAGPATFETVRLANKGQYVIGVDSDQ----GMIQDK 304 Query: 272 DTIMTSVVKNVDTGVFDLV 290 D I+TSV+K++ V++ + Sbjct: 305 DRILTSVLKHIKQAVYETL 323
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.8 bits (72), Expect = 0.007 Identities = 23/103 (22%), Positives = 36/103 (34%), Gaps = 16/103 (15%) Query: 220 TTTKQLAELMVGSELPSPETRESTVTDIPMLTVE------GLRLTAT-DPDGVVRSVLDG 272 T A VG E+P ++T D TVE L++ + V ++ Sbjct: 447 TLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVERKTVGIKLKVKPQINEGDSVLLEIE- 505 Query: 273 IGFTIHKGEVLGIAGVEGNGQSELVDAIMGMRHLDTGVLTLDG 315 EV +A + S+L A R ++ VL G Sbjct: 506 -------QEVSSVADAASSTSSDL-GATFNTRTVNNAVLVGSG 540
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 29.4 bits (66), Expect = 0.026 Identities = 23/71 (32%), Positives = 33/71 (46%), Gaps = 5/71 (7%) Query: 62 AALAMAVPIGLAGLGGLWAERAGV-VNIGLEGM----MILGTFFGAWAGWQTNPWLGVLA 116 +L AV +AG LW+ + G EGM L GAW GWQ P + +L+ Sbjct: 179 VSLGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLS 238 Query: 117 GVIGGALGGLL 127 ++G +G L Sbjct: 239 SLVGAFMGIGL 249
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.020 Identities = 12/41 (29%), Positives = 16/41 (39%), Gaps = 3/41 (7%) Query: 368 ELHAKPGDTVTAGQPLLTLHTDTPEKFDYALKALPSSYDIA 408 E+ K G++V G LL L T + SS A Sbjct: 109 EIIVKEGESVRKGDVLLKL---TALGAEADTLKTQSSLLQA 146
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 233 bits (595), Expect = 6e-71 Identities = 111/304 (36%), Positives = 152/304 (50%), Gaps = 38/304 (12%) Query: 188 VPQIGVPSAWKAGYTGKGVKIAVLDTGVDTTHPDLQGQILDTKNFTSS-----PDTKDRV 242 V I P+ W G+GVK+AVLDTG D HPDL+ +I+ +NFT KD Sbjct: 26 VEMIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYN 84 Query: 243 GHGTHVSSIAAGTGAKSGGKLKGVAPDAKLLEGKVLDDDGFGDDSGILAGMEWAVAQGAD 302 GHGTHV+ A T ++G GVAP+A LL KVL+ G G I+ G+ +A+ Q D Sbjct: 85 GHGTHVAGTIAATENENGVV--GVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVD 142 Query: 303 IINLSLGGGDTPEIDPLEAAVNKLSADKGVLFAIAAGNEGAGAG---TVGSPGSADAALT 359 II++SLGG + ++ L AV K +L AAGNEG G +G PG + ++ Sbjct: 143 IISMSLGGPE--DVPELHEAVKKA-VASQILVMCAAGNEGDGDDRTDELGYPGCYNEVIS 199 Query: 360 VGAVDDNDELADFSSRGPRNGDGAIKPDVTAPGVDITAAAAPGSAIDQEVGQNPPGYLTI 419 VGA++ + ++FS+ + D+ APG DI + G Y T Sbjct: 200 VGAINFDRHASEFSNSNN-------EVDLVAPGEDILSTVPGG------------KYATF 240 Query: 420 SGTSMATPHVAGAAALLKQQ-----HPQWKYAELKGALTASTKPGAYTPFEQGSGRIAVD 474 SGTSMATPHVAGA AL+KQ EL L T P +P +G+G + + Sbjct: 241 SGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLT 300 Query: 475 KAIA 478 Sbjct: 301 AVEE 304
>PF06776#Invasion associated locus B Length = 214 Score = 32.2 bits (73), Expect = 0.001 Identities = 13/46 (28%), Positives = 17/46 (36%), Gaps = 1/46 (2%) Query: 11 RARRALALSVTGLMAAPALVLGTGGSAQAASCTTST-GPYQKQVEK 55 ARR A + A AL G A A S G +Q + + Sbjct: 44 LARRNGARLMLAGAMAIALSFGWSDRADAQGAVRSVHGDWQIRCDT 89
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 60.7 bits (147), Expect = 4e-12 Identities = 64/366 (17%), Positives = 117/366 (31%), Gaps = 49/366 (13%) Query: 68 LPAISASLGATAGQASWTVSAATGALALCVLPMSALSERFGRRQMMTASLTVAVLVGLLV 127 LP I+ +W +A ++ LS++ G ++++ + + ++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 128 PFAPS-LGWLIALRAVQGAALAGLPASAMAYLAEEVRPKALVAAIGLFVAGNSIGGMSGR 186 S LI R +QGA A PA M +A + + A GL + ++G G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 187 ILTGWVAQLWGWRAALGAVGLLAVACAVVFHFMIPRARNFTPGTLNPKALAKTVGEHLSD 246 + G +A W L + + + + R G + K + + Sbjct: 157 AIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVR--IKGHFDIKGIILMSVGIVFF 214 Query: 247 PLLRRLYAIGALFMTVFGAVYTVIGYRLVEAPF--------------------------- 279 L Y+I L ++V + V R V PF Sbjct: 215 MLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAG 274 Query: 280 -------------SLPQGVVGSIFL--VYLVGTVSSAAAGRLVARLGRRGALYLAVSTTA 324 L +GS+ + + + G LV R G L + V+ + Sbjct: 275 FVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLS 334 Query: 325 AGLL-LSLADQLAAVL--LGLVLITAGFFAGHAVASSSVSRTATKGRAQASA-LYQSAYY 380 L S + + + +V + G V S+ VS + + A A L + Sbjct: 335 VSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF 394 Query: 381 VGSSAG 386 + G Sbjct: 395 LSEGTG 400
>PF06580#Sensor histidine kinase Length = 349 Score = 41.0 bits (96), Expect = 7e-06 Identities = 16/107 (14%), Positives = 36/107 (33%), Gaps = 24/107 (22%) Query: 388 ILANLIGNALKHGGSP------VRVSVRTEGDELVIEVRDHGPGIPEDVLPHVFDRFYKA 441 ++ L+ N +KHG + + + + + +EV + G ++ Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT----------- 307 Query: 442 SASRPRSEGSGLGLSIAMEN-AHIHGGDITAANSPDGDGAVFVLRLP 487 E +G GL E ++G + S ++ +P Sbjct: 308 ------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 95.7 bits (238), Expect = 6e-25 Identities = 40/139 (28%), Positives = 74/139 (53%), Gaps = 4/139 (2%) Query: 7 LLLIEDDDAIRTALELSLSRQGHRVATAATGEDGLKLLREQRPDLIVLDVMLPGIDGFEV 66 +L+ +DD AIRT L +LSR G+ V + + + DL+V DV++P + F++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 67 CRRIRRTD-QLPIILLTARSDDIDVVVGLESGADDYVVKP-VQGRVLDARIRAV--LRRG 122 RI++ LP+++++A++ + + E GA DY+ KP ++ RA+ +R Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRR 125 Query: 123 ERESTDSAAFGNVVIDRSA 141 + D + G ++ RSA Sbjct: 126 PSKLEDDSQDGMPLVGRSA 144
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.014 Identities = 15/57 (26%), Positives = 23/57 (40%), Gaps = 6/57 (10%) Query: 59 MAVVDAPVGANGGSGGG------AAYGEVIGERKPPAQAEDAETAFTAYVRERRASL 109 +A V +P A GG+GGG + P +D E F ++ + A L Sbjct: 384 LADVSSPTAAAGGAGGGEPPKKRDPSAGAGTDPGGPGGGDDGEDPFGEWLDDEVARL 440
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 27.3 bits (61), Expect = 0.025 Identities = 11/28 (39%), Positives = 16/28 (57%) Query: 87 KDQFVREVADAEGLSKSKAAAVVDAAID 114 K + +VA+A L+K +AA VDA Sbjct: 4 KQDLIAKVAEATELTKKDSAAAVDAVFS 31
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.8 bits (163), Expect = 7e-15 Identities = 31/153 (20%), Positives = 56/153 (36%), Gaps = 13/153 (8%) Query: 12 SSILIVDDMEENLVALEAVLGSLA-QVVRAQSGEEALKAMLRQEFAVVLIDVMMPGMNGF 70 ++IL+ DD L L V + + + + +V+ DV+MP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 ETAANIKGLDQTKDVPIILLTGAAVDPNYAYRGYTVGAADFLIKPFDPWLLRTKVNVFLD 130 + IK D+P+++++ A + GA D+L KPFD L + Sbjct: 64 DLLPRIKKAR--PDLPVLVMSAQN-TFMTAIKASEKGAYDYLPKPFD---LTELIG---- 113 Query: 131 LHRKNRQLVDQAEQLKRLLTADGGHPGIPSAAP 163 R L + + +L + + Sbjct: 114 --IIGRALAEPKRRPSKLEDDSQDGMPLVGRSA 144
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.8 bits (215), Expect = 2e-19 Identities = 39/137 (28%), Positives = 62/137 (45%), Gaps = 3/137 (2%) Query: 1264 RILIVDDDIRNVFALTHVLGRVGISVKYAENGREGLEVLDRTPDVSLVLMDIMMPEMDGY 1323 IL+ DDD L L R G V+ N + LV+ D++MP+ + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGD-GDLVVTDVVMPDENAF 63 Query: 1324 EMIAAIRRTPRFAGLPVIALTAKAMPGDREKAIESGANDYVPKPVDVDRLLSVICRLLDP 1383 +++ I++ LPV+ ++A+ KA E GA DY+PKP D+ L+ +I R L Sbjct: 64 DLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 1384 QCTSPEPRPDPSDNARS 1400 P D S + Sbjct: 122 PKRRPSKLEDDSQDGMP 138
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 41.1 bits (96), Expect = 3e-06 Identities = 28/161 (17%), Positives = 53/161 (32%), Gaps = 15/161 (9%) Query: 71 PALVLSNGHCMESGFPGPGEVVFNQPSTRSFTLLNASGSGVGTLRASKIAYGTMTDTDIS 130 +L+N H +++ P + + N G A +I + D++ Sbjct: 111 KDTLLTNKHVVDATHGDPHALKAFPSAI------NQDNYPNGGFTAEQI-TKYSGEGDLA 163 Query: 131 VYQLTRTYAQIESSYGIKALELNTAHPVQ-GTAITVVSGYWKRTYACNVDGFVYRLKEGE 189 + + + +K ++ Q ITV Y + +G+ Sbjct: 164 IVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTG------YPGDKPVATMWESKGK 217 Query: 190 WTWKDSVRYTSACQTIGGTSGSPVIDNATGKVVAVNNTGNE 230 T+ T GG SGSPV N +V+ ++ G Sbjct: 218 ITYLKGEAMQYDLSTTGGNSGSPVF-NEKNEVIGIHWGGVP 257
>TETREPRESSOR#Tetracycline repressor protein signature. Length = 218 Score = 58.0 bits (140), Expect = 3e-12 Identities = 44/231 (19%), Positives = 85/231 (36%), Gaps = 38/231 (16%) Query: 38 LSADAIVTAAIAVADEDGMAALSMRAVGERLGRTAMALYTYVPSKSELLDLMYDAVHAEL 97 L+ ++++ AA+ + +E G+ L+ R + ++LG LY +V +K LLD + + A Sbjct: 4 LNRESVIDAALELLNETGIDGLTTRKLAQKLGIEQPTLYWHVKNKRALLDALAVEILARH 63 Query: 98 PTRYAGIDN--WRTGLTDWAHDTLAFLLRHPWVLQVSQARPVLGPHEYTGLDTLVRLLNG 155 W++ L + A LLR+ +V +Y ++T +R + Sbjct: 64 HDYSLPAAGESWQSFLRNNAMSFRRALLRYRDGAKVHLGT-RPDEKQYDTVETQLRFMTE 122 Query: 156 TGLDASLRRRLVGTLTHFVRGCAGTVAEARQAAAVTGESDEEWWFARSALLGEVAPDFAD 215 G + ++HF G V E ++ A D Sbjct: 123 NGFSLRDGLYAISAVSHFTLGA---VLEQQEHTA----------------------ALTD 157 Query: 216 RYPSLSAMESEGTPQQPPSAPGEEAMPYLEREARE-TFAVGLDVMLDGIDA 265 R P + EA+ ++ + E F GL+ ++ G + Sbjct: 158 R---------PAAPDENLPPLLREALQIMDSDDGEQAFLHGLESLIRGFEV 199
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 45.1 bits (107), Expect = 5e-07 Identities = 23/73 (31%), Positives = 35/73 (47%), Gaps = 9/73 (12%) Query: 1 MDVVIRNALVIDGTGTPAHRADVAIGDGRIIEIHPEHAPGPRP-------TGRRTLDADG 53 +D VI NAL++D G +AD+ + DGRI I P +P G + +G Sbjct: 68 VDTVITNALILDHWGI--VKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEG 125 Query: 54 LALSPGFIDMHAH 66 ++ G +D H H Sbjct: 126 KIVTAGGMDSHIH 138
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.027 Identities = 7/41 (17%), Positives = 18/41 (43%) Query: 181 AFWPVLLSILVSPEENTPVWLTVVSLISVMTAFGWASIARL 221 F P L ++ +P P + + ++ AF + + ++ Sbjct: 40 EFLPAHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQV 80
>cloacin#Cloacin signature. Length = 551 Score = 35.5 bits (81), Expect = 6e-04 Identities = 33/132 (25%), Positives = 48/132 (36%), Gaps = 4/132 (3%) Query: 121 SALDEFGHGGPAAGPRPTPNLGVRTPGPSGPTAGPVTGASSLTPNLDGAG---GPGPGGP 177 S D GH A N G G G + +S P G+G G G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 178 RGPGGPAGPQGPGA-SGGVPPRMSDDTAVLTPQFAAPASAGPGGNVSGDTLTSGIPVVPP 236 G GG G G G+ +GG ++ A P + P + G ++S L++ I + Sbjct: 62 HGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIADIMA 121 Query: 237 EHRSPSLFPSAG 248 + P F G Sbjct: 122 ALKGPFKFGLWG 133
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.022 Identities = 49/325 (15%), Positives = 99/325 (30%), Gaps = 45/325 (13%) Query: 54 GALGLLVFVGAYLVLVFRHTSKALDRRAVHTTIAFLGALAAV--LSLTLGAAWLVLFVYV 111 G L F A L + S + I+ +G + S WL L + Sbjct: 21 GVYTLTGFGFASLYGSPKLHS-----MIFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQ 75 Query: 112 AVSVGATMPLRNARWLIPVVVSALVCIGLTVDHPREITTAL----VFPALFGGFAMTGVR 167 + + S + P T L +F + F + + Sbjct: 76 IILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLY 135 Query: 168 QLIRTTIQLREARATVAQLAANEERLRLARDLHDLLGHSL--SLITLKSELAGRMLPGHP 225 ++A ++A+ + +L + H + +L +++ ++ P Sbjct: 136 FGWHFFKNYKQAEIDQWKMASMAQEAQLMALKAQINPHFMFNALNNIRA-----LILEDP 190 Query: 226 EQAAAQVADIEQVSRQALVDVRSAVTGYRRPTLPGELAGARTALAAAGI--------TAD 277 +A + + ++ R +L + +L EL + L A I Sbjct: 191 TKAREMLTSLSELMRYSLRYSNARQV-----SLADELTVVDSYLQLASIQFEDRLQFENQ 245 Query: 278 VPADAPDGLPEKPEEVLAWALREAVTNVVRH---SSARHCTVILTPRQTLDGRALELTVA 334 + +V ++ V N ++H + ++L + D + L V Sbjct: 246 INPAI------MDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTK--DNGTVTLEVE 297 Query: 335 DDGVGAAGTKP---GNGLTGITERL 356 + G A G GL + ERL Sbjct: 298 NTGSLALKNTKESTGTGLQNVRERL 322
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 2e-14 Identities = 26/135 (19%), Positives = 51/135 (37%), Gaps = 2/135 (1%) Query: 1 MSMIRLLLAEDQSMVREALAALLGLEPDIEVVAQVARGDEVLAAAHEHRIDVALLDIEMP 60 M+ +L+A+D + +R L L V + + D+ + D+ MP Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 GMTGIDAAAALRRELPAVKVVVVTTFGRPGYLRRAMESGADAFLVKDAPAAQLAAAVRKV 120 D +++ P + V+V++ +A E GA +L K +L + + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LAGERVIDPTLAAAA 135 LA + L + Sbjct: 119 LAEPKRRPSKLEDDS 133
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 27.6 bits (61), Expect = 0.040 Identities = 23/132 (17%), Positives = 35/132 (26%), Gaps = 10/132 (7%) Query: 20 LGRALMWP---------AVAAGVGMLVIYNSIETSVDDKPPAPPAAVAPAAVPEVLGSHA 70 L R WP AV AG+ ++ IE +P + VAPA + Sbjct: 10 LPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQPISV-TMVAPADLEPPQAVQP 68 Query: 71 APRPVTPSAPAVGPAMSRSVPTRLQIPSLAVKAPFTDLSIGADGRLNPPPPNDSNLVGWF 130 P PV P P + I K + + + Sbjct: 69 PPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASP 128 Query: 131 KGGVTPGERGAA 142 P ++ Sbjct: 129 FENTAPARPTSS 140
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 27.8 bits (62), Expect = 0.046 Identities = 11/22 (50%), Positives = 16/22 (72%) Query: 8 VAVTGASGAVGGRVAQRLVRAG 29 VTGA+G +G V++RL+ AG Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAG 24
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.0 bits (119), Expect = 7e-10 Identities = 21/168 (12%), Positives = 47/168 (27%), Gaps = 10/168 (5%) Query: 12 RPGGRTARVRESVLRAAGDALAEHGFDRLDLADVARRAEVGKTTVYRRWSTPTGLIADLL 71 + R+ +L A ++ G L ++A+ A V + +Y + + L +++ Sbjct: 4 KTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIW 63 Query: 72 DDMAEQSSPRTDT------GSLTEDLRANARLVVTTLTDPRQGALFKSVIAAATCDPRTT 125 + G LR V+ + + L +I Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 126 EALHRFYAIRIKEW----SGCVTEAVERGELPAGTDADEVIRAVSAPL 169 + + E + +E LPA + + Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYI 171
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 116 bits (291), Expect = 3e-30 Identities = 88/413 (21%), Positives = 180/413 (43%), Gaps = 16/413 (3%) Query: 29 RQKLVLALLLGAQFMIAVDFSILNVALPVVGEGLGFSLSHLQWIATAFALAAAGFTLLFG 88 R +L L F ++ +LNV+LP + + W+ TAF L + T ++G Sbjct: 11 RHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYG 70 Query: 89 RVADLVGRKRLFLGGMVVLGLSSALGGLATSP-EVLLTARVLQGLATAAVTPAGLALLTT 147 +++D +G KRL L G+++ S +G + S +L+ AR +QG AA PA + ++ Sbjct: 71 KLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAF-PALVMVVVA 129 Query: 148 AFKEGPLRERALGLNGALMSAGFTAGAILGGLLTDLLSWRWAFFVNVPVAALVVFLAPAV 207 + R +A GL G++++ G G +GG++ + W++ + +P+ ++ Sbjct: 130 RYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIH--WSYLLLIPMITIITVPFLMK 187 Query: 208 ITDSRPARRPRLDVPGAVTVTGGLLLLVYGLTQAGESGWTTPTTLVALLAGLALLLGFWS 267 + + D+ G + ++ G++ + T + +++ L+ L+ F Sbjct: 188 LLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSY--------SISFLIVSVLSFLI-FVK 238 Query: 268 IEKRAASPLVPVHILKRRSVIWGNTVGLIAFVTETSLVFLLTLYLQEVLGYSPLATGLAF 327 ++ P V + K + G G I F T V ++ +++V S G Sbjct: 239 HIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVI 298 Query: 328 GVLG-IGTVIGGAFGGRAVGRYGSRMTIVTGGVIQAVATLCLVALGTSGAWIWLLLVATF 386 G + +I G GG V R G + G +V+ L L + +W +++ Sbjct: 299 IFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFV 358 Query: 387 IGGIGNMLVIVGFMVTATSGLPDEEQGLATGLATMTQQVGITMGIPVMSAVVT 439 +GG+ ++ +V+++ L +E G L T + GI ++ +++ Sbjct: 359 LGGLSFTKTVISTIVSSS--LKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 27.7 bits (61), Expect = 0.020 Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 8/83 (9%) Query: 51 DWLLVQYGATV-RPGDVVILRHPFQQDLLIVKRAAERRRGGW-----WVLADNPFAGGDS 104 +WLL Q R G L +P +Q + + AE+R W W+ +P G + Sbjct: 12 EWLLAQTATECQRHGREATLEYPTRQGMWVRLSDAEKRWSAWIKPGDWLEHVSPALAGAA 71 Query: 105 TDYGTVPEELVLARVRARYRPLK 127 G E LV+ + A RP + Sbjct: 72 VSAGA--EHLVVPWLAATERPFE 92
>PF06917#Periplasmic pectate lyase Length = 555 Score = 27.2 bits (60), Expect = 0.040 Identities = 11/26 (42%), Positives = 14/26 (53%), Gaps = 4/26 (15%) Query: 50 RRHGRLDNIEAYARKTLINTYIAACR 75 R+ R+DN A A TL IAA + Sbjct: 492 HRYFRIDNPIALALLTL----IAAKQ 513
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 27.5 bits (61), Expect = 0.003 Identities = 13/67 (19%), Positives = 25/67 (37%), Gaps = 1/67 (1%) Query: 3 EATDLAARAGDRDPRVGLRAVAALRRLLEQLEAVQVRSA-RVQGWSWQEIAAELGVSRQA 61 +A + R L R+L ++E + +A + + A LG++R Sbjct: 406 QAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNT 465 Query: 62 VHKKYGR 68 + KK Sbjct: 466 LRKKIRE 472
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 28.5 bits (63), Expect = 0.049 Identities = 21/100 (21%), Positives = 46/100 (46%), Gaps = 2/100 (2%) Query: 137 GRKSDWESAFGDLGDFGDKETWRAAKEELRKA--KQEWKEQARRAKDESRRAREDAQQAR 194 G+ ++ A D + G+ + + A+++L K+ K+E E+ K ES+ ++ +A+ Sbjct: 586 GKTLNFNKAVADAKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAK 645 Query: 195 RQAKEAQDRAREQMQNAARQVQEHFARGDWPSGVREGLAE 234 QA +D + A + A G++ L++ Sbjct: 646 AQANSQKDEIFALINKEANRDARAIAYAQNLKGIKRELSD 685
>PERTACTIN#Pertactin signature. Length = 922 Score = 31.2 bits (70), Expect = 0.003 Identities = 20/58 (34%), Positives = 23/58 (39%) Query: 136 QTPPQAAASPATQAAPPMPPPPSSPPGHPPAPTAPPAAVPGASAGNPDAGASTGAPAH 193 + PP +P P PP P PP P PP P A A P AG A A+ Sbjct: 566 KAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPAGRELSAAAN 623
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 39.6 bits (92), Expect = 3e-05 Identities = 33/182 (18%), Positives = 55/182 (30%), Gaps = 42/182 (23%) Query: 46 GFLGSGFFIAPSWVLTCAHVAMEGEGRHVNVVFKPDPGSAETAVEGAVVVALPERRHAAA 105 F+ SG + +LT HV G + A P + Sbjct: 101 TFIASGVVVGKDTLLTNKHVVDATHGDPHALK------------------AFPSAINQDN 142 Query: 106 GPGGV----RVPAPSGGWPAPDLALIRL--LRPVEHPCVYVTERPAGMFG----GGSVLY 155 P G ++ SG DLA+++ +H V ++ Sbjct: 143 YPNGGFTAEQITKYSGE---GDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITV 199 Query: 156 TGWT-DGGSGQLTRFSGRCQVMGTFGDWAEDDEQMRLDGDRMYPGLSGGPVVDLARGEVV 214 TG+ D + G+ + M+ D G SG PV + + EV+ Sbjct: 200 TGYPGDKPVATMWESKGKITYLKGEA--------MQYDLS-TTGGNSGSPVFN-EKNEVI 249 Query: 215 GV 216 G+ Sbjct: 250 GI 251
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 39.0 bits (90), Expect = 1e-04 Identities = 27/82 (32%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Query: 45 PLLSAGPAEAGRPAGRPAPQVTGDEAPDPAPDDDEPAEQRDLGDADRRIALYPVPRTASP 104 P L+ G AEA P +P P+V+ E P P +E R + D + P T Sbjct: 313 PDLTPGSAEA--PNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTDGQ 370 Query: 105 GGPRPDGPAGRGRSAARGGRAR 126 G RPD PA R R + R Sbjct: 371 PGTRPDSPAVPDRPNGRHRKER 392
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 42.7 bits (100), Expect = 1e-06 Identities = 36/249 (14%), Positives = 71/249 (28%), Gaps = 16/249 (6%) Query: 42 SLEKRIEELHLETQNAQAQVNDAEPSYAGLGARVEKILRLAEEEAKDLREEARRAAE--Q 99 + E E +++ + A R +EAK + + E Q Sbjct: 1031 ATPSETTETVAENSKQESKTVEKNEQDA---TETTAQNREVAKEAKSNVKANTQTNEVAQ 1087 Query: 100 HRELAESAAQQVRNDAESFAAERKAKAEDEGVRIVEKAKGEAT--SLRTEAQKDAAQKRE 157 + + + E KAK E E + V K + + ++E + A+ Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAR 1147 Query: 158 EADALFEETRAKAAQAAADFETNLAKRRDQSERDLASRQAKAEKRLAEIEH--------R 209 E D ++ AK + + + +E+ Sbjct: 1148 ENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATT 1207 Query: 210 AEQLRLEAEKLRTDAERRARQTVETAQRQSEDIVADANAKADRIRSESERELAALTNRRD 269 + E+ + RR+ ++V + D + A S A L++ R Sbjct: 1208 QPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVA-LCDLTSTNTNAVLSDARA 1266 Query: 270 SINAQLTNV 278 NV Sbjct: 1267 KAQFVALNV 1275
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 62.4 bits (151), Expect = 1e-11 Identities = 54/387 (13%), Positives = 116/387 (29%), Gaps = 38/387 (9%) Query: 192 NETRQRLGSEAESARADAEAILLRARK-DAERLLNAASSQAQEATSHAEQLRTSTTAETE 250 R L D A + R + L + + T + T + + Sbjct: 947 KAQRDHLNVSLVGNTVDLGAWKYKLRNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQAD 1006 Query: 251 QTRQQTTELNRA---------------AEQRMQEAETQLREARLAAEKVTSEAKEA-AVK 294 + A +E AE +E++ EK +A E A Sbjct: 1007 VPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK-TVEKNEQDATETTAQN 1065 Query: 295 RLAAAESQNEQRTRTARSEIARLVGEA-------TKDAESLKAEAEQ-ALADARAEADRL 346 R A E+++ + T +E+A+ E TK+ +++ E + + E ++ Sbjct: 1066 REVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKV 1125 Query: 347 KSEAAEKARTAAAEDAAAQLAKAARAAEEVLTKASEDAK-STTRAASEEADRIRREAETE 405 S+ + K + A+ A+ + S+ + T ++E + TE Sbjct: 1126 TSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTE 1185 Query: 406 ADRLRG--EAAEQADQLKGAAKDDTKEYRAKTVELQEEARRLRGEAEQLRSEAVAEGERI 463 + + E + A T + R +R + + + Sbjct: 1186 STTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSND-- 1243 Query: 464 RGEARREAVQQIEEGAKTAEELLSKAKADAEE--LRTTAGTESERVRTEATERATALRKQ 521 R V + + +LS A+A A+ L + E Sbjct: 1244 -----RSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNNEGQYNVWV 1298 Query: 522 AEEALERARAEAEQLRTESEEQARSVT 548 + ++ + + ++ R S+ + Sbjct: 1299 SNTSMNKNYSSSQYRRFSSKSTQTQLG 1325 Score = 52.8 bits (126), Expect = 1e-08 Identities = 36/266 (13%), Positives = 81/266 (30%), Gaps = 26/266 (9%) Query: 433 AKTVELQEEARRLRGEAEQLRSEAVAEGERIRGEARREAVQQIEEGAKTAEELLSKAKAD 492 ++T E E + + + + E E +EA ++ +T E ++++ ++ Sbjct: 1034 SETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE--VAQSGSE 1091 Query: 493 AEELRTTAGTES------ERVRTEATERATALRKQAEEALERARAEAEQLRTESEEQARS 546 +E +TT E+ E+ + E + + ++ + ++ ++E Q + E + Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 547 VTTVAEQAAAELREETERAVAARQAKAADELTRLHTEAETRVTTAEQALNDARSEAE--- 603 + E + A + ++ T T + E N + + Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 604 ----------RIRRETNEESERLRAEAAERLRALQEQAETEAERLRDEAAADASRSRAEG 653 R RR + T A +A S A Sbjct: 1212 NSESSNKPKNRHRRSVRSVPHNVEPATTS-----SNDRSTVALCDLTSTNTNAVLSDARA 1266 Query: 654 ESAAVRLRSEAAAEAERLKSEAQESA 679 ++ V L A + E Sbjct: 1267 KAQFVALNVGKAVSQHISQLEMNNEG 1292 Score = 50.8 bits (121), Expect = 4e-08 Identities = 38/310 (12%), Positives = 94/310 (30%), Gaps = 10/310 (3%) Query: 685 EAAAAAERVGTEAAEALAAAQEEANRRRREAEETLDAARTEANQERERAREQSEELLASA 744 E + V T Q + EE ++ E +A Sbjct: 984 EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043 Query: 745 RKRVEQAQAEAQRLVEEADSRAMELVSAAEQTAQQVRDSVNGLQEQAEAEIAGLRSAAEH 804 K+ + VE+ + A E + + A++ + +V + E +G + Sbjct: 1044 SKQESKT-------VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 805 VAERTKSEAQEEADR--VRSDAHAERDRASEDAARIRREAQEESEAAKAMAERTVSDAIA 862 E ++ E+ ++ V ++ E + + + + +++ A+ E + I Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIK 1156 Query: 863 ESERLRADTAEYSQRMRTEASDALASAEQDAARSRAEAREDANRMRSDAATQ-ADRLVGE 921 E + TA+ Q + +S+ + + + + + A TQ Sbjct: 1157 EPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESS 1216 Query: 922 ATSEAERIRTESTQQATQLAEEATQQATRLVDEATQQATRVADEATDGAERLRAEAAATV 981 + R+ + + V +T +D + + A Sbjct: 1217 NKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVG 1276 Query: 982 ASAQEHAART 991 + +H ++ Sbjct: 1277 KAVSQHISQL 1286 Score = 46.2 bits (109), Expect = 9e-07 Identities = 48/322 (14%), Positives = 97/322 (30%), Gaps = 26/322 (8%) Query: 63 PAYDSADIGYQAEQLLRNAQIQAEQLRTDAERELRDARAQTQRILQEHAEHQARLQAELH 122 P + + + IQA+ + E AR + A E Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEI-ARVDEA-PVPPPAPATPSETTETV 1040 Query: 123 NEAVQRRQQLDQELAERRQTVESHVNENVAWAEQLRARTESQARRL-------LEESRAE 175 E +++ E E+ T + N VA + + +Q + E E Sbjct: 1041 AEN-SKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099 Query: 176 AEQSLAAARAEAGRLANETRQ---RLGSEAESARADAEAILLRARKDAER--LLNAASSQ 230 +++ + E ++ E Q ++ S+ + +E + +A E +N Q Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQ 1159 Query: 231 AQEATSHAEQL---RTSTTAETEQTRQQTTE-LNRAAE--QRMQEAETQLREARLAAEKV 284 +Q T+ + TS+ E T T N E + A TQ ++ K Sbjct: 1160 SQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKP 1219 Query: 285 TSEAKEAAVKRLAAAESQNEQRTRTARSEIARLVGEATKDAESLKAEAEQALADARAEAD 344 + + + E + + L T S Q +A + Sbjct: 1220 KNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVA-----LN 1274 Query: 345 RLKSEAAEKARTAAAEDAAAQL 366 K+ + ++ + + Sbjct: 1275 VGKAVSQHISQLEMNNEGQYNV 1296 Score = 46.2 bits (109), Expect = 1e-06 Identities = 49/330 (14%), Positives = 109/330 (33%), Gaps = 26/330 (7%) Query: 441 EARRLRGEAEQLRSEAVAEGERIRGEARREAVQQIEEG--AKTAEELLSK-AKADAEELR 497 E R + + + + + + E + +++E A S+ + AE + Sbjct: 986 EKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSK 1045 Query: 498 TTAGTESERVRTEATERATALRKQAEEALERARAEAEQLRT--ESEEQARSVTTVAEQAA 555 + T E+ +ATE R+ A+EA +A + E + TT ++ A Sbjct: 1046 QESKTV-EKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA 1104 Query: 556 AELREETERAVAARQAKAADELTRLHTEAETRVTTAEQALNDARSEAERIRRETNEESE- 614 +EE + + + T++ + +SE + + E E++ Sbjct: 1105 TVEKEEKAKVETEKTQEVPK-------------VTSQVSPKQEQSETVQPQAEPARENDP 1151 Query: 615 RLRAEAAERLRALQEQAETEAERLRDEAAADASRSRAEGESAAVRLRSEAAAEAERLKSE 674 + + + E A+ + S +V E A + Sbjct: 1152 TVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTV 1211 Query: 675 AQESADRVRSEAAAAAERVGTEAAEALAAAQEEANRRRREAEETLDAARTEANQERERAR 734 ES+++ ++ + V A ++ + R D T N AR Sbjct: 1212 NSESSNKPKNRHRRSVRSVPHNVEPATTSSND------RSTVALCDLTSTNTNAVLSDAR 1265 Query: 735 EQSEELLASARKRVEQAQAEAQRLVEEADS 764 +++ + + K V Q ++ + E + Sbjct: 1266 AKAQFVALNVGKAVSQHISQLEMNNEGQYN 1295 Score = 45.1 bits (106), Expect = 2e-06 Identities = 50/336 (14%), Positives = 104/336 (30%), Gaps = 27/336 (8%) Query: 846 SEAAKAMAERTVSDAIAESERLRADTAEYSQRMRTEASDALASAEQDAARSRAEAREDAN 905 +++A V+D E + S+ R + +L D + + R Sbjct: 917 TKSATGNFTLQVADKTGEPNHNELTLFDASKAQRDHLNVSLVGNTVDLGAWKYKLRNVNG 976 Query: 906 RMRSDAATQADRLVGEATSEAERIRTESTQQATQLAEEATQQATRLVDEATQQATRVADE 965 R R T + I T + QA + + + VDEA Sbjct: 977 RYDLYNPEVEKR---NQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVP------- 1026 Query: 966 ATDGAERLRAEAAATVASAQEHAARTREESEQVRADAEAAAEQMRAEARQEADRLLDEAR 1025 A +E TVA + ++T E++EQ + A ++ EA+ Sbjct: 1027 --PPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNE 1084 Query: 1026 EAAAKRRADAAEQADQLINKAQEEALRAATEAEEQADTMVGVARKEAVRITSEATVEGNS 1085 A + + + E+ +A E E+ E ++TS+ + + Sbjct: 1085 VAQSGSETKETQTTETKETATVEKEEKAKVETEKTQ---------EVPKVTSQVSPKQ-- 1133 Query: 1086 LVERARTDADELLVGARRDATAIRERAEELRTRIESEIEELHDRARRETSEQM-KTAGER 1144 E++ T + D T + + ++ E+ + + ++ Sbjct: 1134 --EQSETVQPQAEPARENDPTVNIKEPQSQTNT-TADTEQPAKETSSNVEQPVTESTTVN 1190 Query: 1145 VDNLMKAATEQRDDAAAKAKELLADANSEASKVRIA 1180 N + E A + +N ++ R + Sbjct: 1191 TGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRS 1226
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.042 Identities = 15/68 (22%), Positives = 26/68 (38%) Query: 9 EQARAGRPRAVARLISLVEGASPQLREVMAALAPLTGNAYVVGLTGSPGVGKSTSTSALV 68 + R + ++ + G S ++E+ LA L + +TG G GK AL Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALH 181 Query: 69 SAYRRAGK 76 +R Sbjct: 182 DYGKRRNG 189
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 47.4 bits (112), Expect = 2e-07 Identities = 30/81 (37%), Positives = 41/81 (50%), Gaps = 8/81 (9%) Query: 133 AGIVHRDVKPGNVML--ASDGPRLIDFGIARDAGATPLTTTSRMVGSPAFMSPEHVAGSG 190 AG+VH D+KPGNV+ AS P +ID G+ +G P T +F +PE G+ Sbjct: 264 AGVVHNDIKPGNVVFDRASGEPVVIDLGLHSRSGEQPKGFTE------SFKAPELGVGNL 317 Query: 191 RVVPASDVFCLASVLCYAATG 211 SDVF + S L + G Sbjct: 318 GASEKSDVFLVVSTLLHCIEG 338
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.1 bits (195), Expect = 3e-19 Identities = 30/118 (25%), Positives = 57/118 (48%) Query: 2 RLLIVEDEKRLAMSLAGGLAAEGFAVDVVHDGLEGLHRAAEGAYDLVVLDIMLPGMNGYR 61 +L+ +D+ + L L+ G+ V + + A G DLVV D+++P N + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VCAALRAAGHEMPILMLTAKDGEYDEAEGLDTGADDYLTKPFSYVVLVARIRALLRRR 119 + ++ A ++P+L+++A++ + + GA DYL KPF L+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.0 bits (145), Expect = 2e-13 Identities = 32/202 (15%), Positives = 73/202 (36%), Gaps = 13/202 (6%) Query: 11 RTGRPRSAAADEAILEATRASLVDLGWSKLTMSDVATRAGVAKTTLYRRWAGKNELVVDA 70 R + + + IL+ G S ++ ++A AGV + +Y + K++L + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 71 VA-------VLFDELELPDLGSLSADVQAVVLQFAALLERPETQTALMAVV---AESTRD 120 L E + G + ++ +++ E + LM ++ E + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 121 EALRARIRDSIVDRQKRLVLQGRQRAQERGELPVEQDEAVAATTDDLIFDVIAGAVVHRA 180 A+ + + ++ + Q + E LP + AA ++ I+G + + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA---IIMRGYISGLMENWL 179 Query: 181 LVSAEPVDEDWARRFTVLLLAG 202 + AR + +LL Sbjct: 180 FAPQSFDLKKEARDYVAILLEM 201
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.8 bits (67), Expect = 0.006 Identities = 16/68 (23%), Positives = 32/68 (47%), Gaps = 16/68 (23%) Query: 67 SLIIGVLLITLGLTMWFHHIVRVFAG-VAAILLALISIPVANIGGFLI----GF---LFS 118 +L ++L+ L ++ +F + A L+ I++PV +G F I G+ + Sbjct: 343 TLFEAIMLVFL--------VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLT 394 Query: 119 LLGGALSI 126 + G L+I Sbjct: 395 MFGMVLAI 402
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 35.8 bits (82), Expect = 3e-04 Identities = 35/155 (22%), Positives = 62/155 (40%), Gaps = 10/155 (6%) Query: 99 SPSATDSGDKGDTSTPKPS------ATPSASDAAKPETKAADAPAAAAPSASPTPTKSTN 152 +P + SG G K AT S A +T+A A A A + + K+ Sbjct: 28 TPDGSGSGGGGGKGGSKSESSAAIHATAKWSTAQLKKTQAEQAARAKAAAEAQAKAKANR 87 Query: 153 PLDPLGVGDALKDLFDGPDKETASPSPSATTASPKPSQSDAAEPAEKPAEKATDAVKETA 212 + LKD+ + + AS +PSAT + + + AE KA + ++ A Sbjct: 88 D----ALTQRLKDIVNEALRHNASRTPSATELAHANNAAMQAEDERLRLAKAEEKARKEA 143 Query: 213 DKTAAAIRDAADKAGKSVEELDESAKGLDTKKDED 247 + A ++A + + E E+ + L + E+ Sbjct: 144 EAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEE 178
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 33.0 bits (75), Expect = 8e-04 Identities = 53/261 (20%), Positives = 91/261 (34%), Gaps = 15/261 (5%) Query: 2 TTANPAKAMDASTPWAAVLRTETRLFLRE-PASLFWILVFPTALLTILGLIPSFRDPDDA 60 TA P +++ W AV R + + ASL L P L+ + GL Sbjct: 6 VTALPGGSLN----WIAVWRRNYIAWKKAALASLLGHLAEP--LIYLFGLGAGLGVMVGR 59 Query: 61 LGGRRVIDLYVPVSVLL-AMIMAGLQAMPPVLTGYRERGILRRMSTTPVRPSALLTAQIA 119 +GG V AM A + + + M T +R ++ ++A Sbjct: 60 VGGVSYTAFLAAGMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMA 119 Query: 120 LHGAAALGSAALVMAVGRIAFGVTLPGQPFGYVLALLLSTASVLV-LGALLCALSRTTKA 178 A + A + V A Y L ++ T LG ++ AL+ + Sbjct: 120 WAATKAALAGAGIGVVA--AALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDY 177 Query: 179 SAAISSVVNLVMMFSAGVWIPVQSMPDTLRRIVEVTPFGAASQALDRAASGGWPG---WA 235 ++V ++F +G PV +P + P + S L R G P Sbjct: 178 FIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPL-SHSIDLIRPIMLGHPVVDVCQ 236 Query: 236 ELGVMALWAALVTLLATRLFR 256 +G + ++ + L+T L R Sbjct: 237 HVGALCIYIVIPFFLSTALLR 257
>PF06580#Sensor histidine kinase Length = 349 Score = 35.2 bits (81), Expect = 4e-04 Identities = 35/183 (19%), Positives = 68/183 (37%), Gaps = 26/183 (14%) Query: 250 LQVVTSIADTDPALARQHLDRAAALARHSLGEARRSVHDLVPAA--LEHDDLPGALKKTV 307 L + ++ DP AR+ L + L R+SL + V A L D L Sbjct: 179 LNNIRALILEDPTKAREMLTSLSELMRYSLRYSN---ARQVSLADELTVVDSYLQLASI- 234 Query: 308 TGWGERHGVRAEFTVTGTVEPVHDEIAATLLRIAEEALANAGRHA-----GASRVGITLS 362 + R +F + ++ L++ E N +H ++ + + Sbjct: 235 -----QFEDRLQFENQINPAIMDVQVPPMLVQTLVE---NGIKHGIAQLPQGGKILLKGT 286 Query: 363 FMGDELTLDVRDDGCGFDPVALPPYSGAGGFGLGGMRARAERVAG---TVEVETEPGRGT 419 +TL+V + G +AL + G GL +R R + + G +++ + G+ Sbjct: 287 KDNGTVTLEVENTG----SLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN 342 Query: 420 AVC 422 A+ Sbjct: 343 AMV 345
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 70.2 bits (172), Expect = 2e-16 Identities = 37/160 (23%), Positives = 58/160 (36%), Gaps = 8/160 (5%) Query: 9 ITLVVVDDHPVVRDGLRGMFDSAPGFQVLGEASNGVEGVDLVARLDPDVVLMDLRMPGGG 68 T++V DD +R L A G+ V SN +A D D+V+ D+ MP Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 69 GVAAIAELTGRGARSKVLVLTTYDTDSDTLPAIEAGATGYLLKDAPRDELFNAVRAAADG 128 + + VLV++ +T + A E GA YL K EL + A Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121 Query: 129 RTVLSPAVASRLVSRVRTPAAPGNDSLSAREREVLELVAK 168 + G SA +E+ ++A+ Sbjct: 122 PKRR---PSKLEDDSQDGMPLVGR---SAAMQEIYRVLAR 155
>BACINVASINB#Salmonella/Shigella invasin protein B signature. Length = 593 Score = 32.4 bits (73), Expect = 0.004 Identities = 19/80 (23%), Positives = 28/80 (35%) Query: 75 DGADSVATSGALKISAKQGKLTTVKVADPKGTEVEGKIAADGTSWTPDQHLAAATKYKVH 134 D A SV + K++ Q KL ++ ADP + E + G T + Sbjct: 151 DTAKSVYDAATKKLTQAQNKLQSLDPADPGYAQAEAAVEQAGKEATEAKEALDKATDATV 210 Query: 135 AVAKDAKGRESAKDTSFTTL 154 DAK + D T Sbjct: 211 KAGTDAKAKAEKADNILTKF 230
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 773 bits (1997), Expect = 0.0 Identities = 267/571 (46%), Positives = 362/571 (63%), Gaps = 11/571 (1%) Query: 8 AMSIDRHEYASVHGPRAGDRVRLGDSGLTVRVESDAQQYGEEFLAGFGKTARDGLHLKAA 67 + + R YA++ GP GD+VRL D+ L + VE D +GEE G GK RDG+ ++ Sbjct: 2 SYRMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMG-QSQ 60 Query: 68 AVRD--TCDVVISNVLVIDAVQGIRKVSIGIREGRISAIGRAGNPDTLDGVDVVVGTGTT 125 R+ D VI+N L++D GI K IG+++GRI+AIG+AGNPD GV ++VG GT Sbjct: 61 VTREGGAVDTVITNALILDH-WGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTE 119 Query: 126 IVSGEGLIATAGAVDTHVHLLSPRIMEASLASGVTTIIGQEFGPVWGVGVNS----PWAL 181 +++GEG I TAG +D+H+H + P+ +E +L SG+T ++G GP G + PW + Sbjct: 120 VIAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHI 179 Query: 182 RHAFNAFDAWPVNIGFLGRGSSSHEAPLVEALAEGGACGFKVHEDMGAHTRALDTALRVA 241 A DA+P+N+ F G+G++S LVE + GGA K+HED G A+D L VA Sbjct: 180 ARMIEAADAFPMNLAFAGKGNASLPGALVEMV-LGGATSLKLHEDWGTTPAAIDCCLSVA 238 Query: 242 EEHDVQVALHSDGLNECLSVEDTLRVLEGRTIHAFHIEGCGGGHVPNVLKMAGVPNVIGS 301 +E+DVQV +H+D LNE VEDT+ ++GRTIHA+H EG GGGH P+++++ G PNVI S Sbjct: 239 DEYDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPS 298 Query: 302 STNPTLPFGRDAVAEHYGMIVSVHDLKTDLPGDAAMARDRIRAGTMGAEDVLHDLGAIGI 361 STNPT P+ + +AEH M++ H L +P D A A RIR T+ AED+LHD+GA I Sbjct: 299 STNPTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSI 358 Query: 362 TSSDAQGMGRAGETVRRTFAMAGKMKAELGPMDGDGPADDNARVLRYIAKLTINPAIAHG 421 SSD+Q MGR GE RT+ A KMK + G + + +DN RV RYIAK TINPAIAHG Sbjct: 359 ISSDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHG 418 Query: 422 LAHEIGSIETGKLADIVLWRPEFFGAKPQLVLKSGFPAYGVTGDPNAATDTCEPLVLGPQ 481 L+HEIGS+E GK AD+VLW P FFG KP +VL G A GDPNA+ T +P+ P Sbjct: 419 LSHEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPM 478 Query: 482 FGAYGATAADLSVAFVSQAATQLG-ADLMPTRRRRVAVRGTR-GIGPGDLVHNSRTGEVA 539 FGAYG + + SV FVSQA+ G A + + VAV+ TR GIG ++HNS T + Sbjct: 479 FGAYGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIE 538 Query: 540 VDAHSGLVTLDGDPLRSEPADSVSLNRLYFL 570 VD + V DG+ L EPA + + + YFL Sbjct: 539 VDPETYEVRADGELLTCEPATVLPMAQRYFL 569
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 90.8 bits (225), Expect = 8e-25 Identities = 24/172 (13%), Positives = 59/172 (34%), Gaps = 5/172 (2%) Query: 3 PAPRRRNTAPPREEVLAAAMATIAERGLDGLTMAGLGREVGMSSGHLLYYFRTKDELLLQ 62 ++ R+ +L A+ +++G+ ++ + + G++ G + ++F+ K +L + Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 63 TLEWSEGRLGAQRRTLLSGRV-TVRERLDAYIDLYLPDGHRDPHWTLWLEVWNRSQNADD 121 E SE +G + L + L + L +E+ Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 122 DA---RARQAAIEGAWHRDLVALLAEGASRGELRT-VDAERFATRLRALLDG 169 + + Q + + + L L + R A +R + G Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISG 173
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.4 bits (92), Expect = 2e-05 Identities = 59/335 (17%), Positives = 114/335 (34%), Gaps = 64/335 (19%) Query: 37 FFPEGNETANLMNTMGIFAVGFFMRPVGGWLLGRIGDRKGRKAALTLTVTLMSASAVLIA 96 + TA+ + ++A M+ +LG + DR GR+ L +++ + ++A Sbjct: 35 LVHSNDVTAHYGILLALYA---LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMA 91 Query: 97 IAPTYDVAGYGGVAVLLVARLLQGLSVGGEYAASATYLTEASAPHRR----GFASSFQYV 152 AP + VL + R++ G++ G A + Y+ + + R GF S+ Sbjct: 92 TAPF--------LWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACFGF 142 Query: 153 SMTAGQLIGLGLQIILQRNMSDAALHSWGWRIPFIVGALGAAIVFYLRRSMLETEVYAES 212 M AG ++G GL + + PF A + F +L E Sbjct: 143 GMVAGPVLG-GL------------MGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGER 189 Query: 213 GAAEQEDRGTLKAL-WQHKRE--------AFLVMALTMGGTVAYYTYTTYLTKFLSKSAG 263 +E L + W F++ + + + + + + G Sbjct: 190 RPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIG 249 Query: 264 MEKSTASLVSFCALFVFMCIQPLA-----------GLLSDRIGRRPLLITFAVGSTFLTV 312 + S A+ +L M P+A G+++D G ++ ++ Sbjct: 250 I--SLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTG---YILLAFATRGWMAF 304 Query: 313 PIMTMLKHAGTFWPAFGLALLALVVVTGYTSINAC 347 PIM +L G PA + S Sbjct: 305 PIMVLLASGGIGMPA----------LQAMLSRQVD 329
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 30.7 bits (69), Expect = 0.023 Identities = 19/90 (21%), Positives = 35/90 (38%), Gaps = 2/90 (2%) Query: 138 VVAGPQGIRYTHP--DPALIGKHLVGPYKEALAGHGFTKSFSGSQGPSLNSVVPVKRLDG 195 + P + PA + V L G K+ +G+ S S +P L+ Sbjct: 36 RIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFGVSPEKNKAGALDASQMSNLPPSTLNL 95 Query: 196 SVAGVVSVGLTDKSVNSVAARSIPFSIAVG 225 S+ GV++ +S+ ++ + FS V Sbjct: 96 SLTGVMAGDDDSRSIAIISKDNEQFSRGVN 125
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 47.4 bits (112), Expect = 3e-07 Identities = 42/275 (15%), Positives = 84/275 (30%), Gaps = 12/275 (4%) Query: 219 QADLRDARLRLLADDLVRLHTALRSEIADEAALKQRREAAEAELKSALAREAELEDEVRR 278 + + + L + A +A L++ E A + A+ LE E Sbjct: 128 ALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAA 187 Query: 279 LGPRLQRAQQTWYELSQLAERVRGTISLADARVKSAGAAPEEERRGTGFRDPESMEREAA 338 L R ++ + I +A + A + E+ Sbjct: 188 LEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL------------EKALE 235 Query: 339 RIREQEAELEAALEAAEHALDDTAAHRAELERELAAEERRLKDAARAIADRREGLARLNG 398 A ++ E A +AELE+ L + I A L Sbjct: 236 GAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALEA 295 Query: 399 QVNAARSRAGSAKAEIDRLAAARDEAQERAVAAQEEYEQLKAEVEGLDAGDAELGERHEA 458 + ++ A L D ++E + E+++L+ + + +A L +A Sbjct: 296 EKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 355 Query: 459 AKRELAEAEAALSAAREAATAAERKRAAVAARHEA 493 ++ + EA E +E R ++ +A Sbjct: 356 SREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDA 390 Score = 45.4 bits (107), Expect = 1e-06 Identities = 53/331 (16%), Positives = 113/331 (34%), Gaps = 12/331 (3%) Query: 162 EEAAGVLKHRKRKEKALRKLDAMGANLARVQDLTDELRRQLKPLGRQAAVARRAAVIQAD 221 + G + ++ L+A A LA + ++ + + + Sbjct: 127 KALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKA 186 Query: 222 LRDARLRLLADDLVRLHTALRSEIADEAALKQRREAAEAELKSALAREAELEDEVRRLGP 281 +AR L L ++ A L+ + A A + Sbjct: 187 ALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSA 246 Query: 282 RLQRAQQTWYELSQLAERVRGTISLADARVKSAGAAPEEERRGTGFRDPESMEREAARIR 341 +++ + L + + A + A + + ++E E A + Sbjct: 247 KIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEA-----EKAALEAEKADLE 301 Query: 342 EQEAELEAALEAAEHALDDTAAHRAELERELA--AEERRLKDAARAIADR-----REGLA 394 Q L A ++ LD + + +LE E E+ ++ +A+R R RE Sbjct: 302 HQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKK 361 Query: 395 RLNGQVNAARSRAGSAKAEIDRLAAARDEAQERAVAAQEEYEQLKAEVEGLDAGDAELGE 454 +L + + ++A L D ++E ++ E+ +++ L+ + EL E Sbjct: 362 QLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEE 421 Query: 455 RHEAAKRELAEAEAALSAAREAATAAERKRA 485 + ++E AE +A L A +A K+A Sbjct: 422 SKKLTEKEKAELQAKLEAEAKALKEKLAKQA 452 Score = 39.3 bits (91), Expect = 1e-04 Identities = 55/344 (15%), Positives = 111/344 (32%), Gaps = 21/344 (6%) Query: 171 RKRKEKALRKLDAMGANLARVQDLTDELRRQLKPLGRQAAVARRAAVIQADLRDARLRLL 230 + EKAL + + + L+ + A A+ + A+++ L Sbjct: 157 KADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTL 216 Query: 231 ADDLVRLHTALRSEIADEAALKQRREAAEAELKSALAREAELEDEVRRLGPRLQRAQQTW 290 + L A A++K+ A +A LE L L+ A Sbjct: 217 EAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFS 276 Query: 291 YELSQLAERVRGTISLAD---ARVKSAGAAPEEERRGTGFRDPESMEREAARIREQEAEL 347 S + + + + A ++ R+ RD ++ ++ + +L Sbjct: 277 TADSAKIKTLEAEKAALEAEKADLEHQSQVLNANRQSLR-RDLDASREAKKQLEAEHQKL 335 Query: 348 EAALEAAEHA-------LDDTAAHRAELERELAAEERRLKDAARAIADRREGLARLNGQV 400 E + +E + LD + + +LE E E + K + + R L Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAK 395 Query: 401 NAARSRAGSAKAEIDRLAAARDEAQERAVAAQEEYEQLKAEVEGLDAGDAELGERHEAAK 460 A +++ L E +E ++E +L+A++E +A K Sbjct: 396 KQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEA----------EAKALK 445 Query: 461 RELAEAEAALSAAREAATAAERKRAAVAARHEALALGLRRKDGT 504 +LA+ L+ R + + A G + GT Sbjct: 446 EKLAKQAEELAKLRAGKASDSQTPDAKPGNKAVPGKGQAPQAGT 489 Score = 31.2 bits (70), Expect = 0.026 Identities = 56/370 (15%), Positives = 116/370 (31%), Gaps = 30/370 (8%) Query: 696 ELTEGQRRAGERRSASAGLVEELGERRRAAEREKSGVAQQLGRLAGQARGAAGEAERMTA 755 + + S + + L + E S ++L + A + + + A Sbjct: 61 KFEIENNTLKLKNSDLSFNNKALKDHNDELTEELSNAKEKLRKNDKSLSEKASKIQELEA 120 Query: 756 SAARAQEALERATEEAEELAERLLVAEEMPVEEEPNTSVRDRLAADGANARQTEMEARLQ 815 A ++ALE A + + ++ + + E+ + + L A Sbjct: 121 RKADLEKALEGAMNFSTADSAKI---KTLEAEKAALAARKADLEKALEGAM----NFSTA 173 Query: 816 VRTHEERVKALAGRADSLDRGARAEREARARAEQRRARLRHEAAVASAVASGARQLLAHV 875 + ++A ++ E + A + + Sbjct: 174 DSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKA----- 228 Query: 876 EVSVVRAERERDAAEAAKAERERELAAERNQGRELKSELDKLTDSVHRGEVLGAEKRLRI 935 E+ + A ++ + L++ +L ++ +I Sbjct: 229 -----DLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKI 283 Query: 936 EQLEAKALEELGVEPAGLAAEYGPNQLVPPSPAAEGEELPEDPEHPRNQPKPFVRAEQ-- 993 + LEA+ L E A L + A + L D + R K Q Sbjct: 284 KTLEAE-KAALEAEKADLEHQSQVLN-------ANRQSLRRDLDASREAKKQLEAEHQKL 335 Query: 994 EKRLKSAERAYQQLGKVNPLALEEFSALEERHKFLSEQLEDLKKTRADL---IQVIREVD 1050 E++ K +E + Q L + + E LE H+ L EQ + + +R L + RE Sbjct: 336 EEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAK 395 Query: 1051 ERVEQVFTEA 1060 ++VE+ EA Sbjct: 396 KQVEKALEEA 405
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 24/90 (26%), Positives = 37/90 (41%), Gaps = 1/90 (1%) Query: 75 IGAATAGRIADRIGRIRCMQIASVLFTISAVGSALPFALWDLAMWRIIGGFAIGMASVIG 134 A G ++DR GR + ++ + A LW L + RI+ G +V G Sbjct: 58 ACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAG 117 Query: 135 PAYIAEVSPPAYRGRLGSFQQAAIVIGIAI 164 AYIA+++ R R F A G+ Sbjct: 118 -AYIADITDGDERARHFGFMSACFGFGMVA 146
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 40.4 bits (94), Expect = 6e-06 Identities = 41/192 (21%), Positives = 71/192 (36%), Gaps = 18/192 (9%) Query: 17 VISGLVVSSRKKKQLPPAPSSTPTIT---------PPAEPHVGEEAETPREEPRRTIEEV 67 V++GL+ +S + PAP+ ++T P A E P EP E + Sbjct: 23 VVAGLLYTSVHQVIELPAPAQPISVTMVTPADLEPPQAVQPPPEPVVEPEPEP----EPI 78 Query: 68 APPSVEAPAEEAPETVEPEAPAAPALEVPEPTAGRLVRLRARLARSQNSLGKGLLTLLSR 127 P EAP +P+ P +V E + + +R A + LT + Sbjct: 79 PEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAPARLTSSTA 138 Query: 128 DNL--DEDTWEEIEDTLLTADVGVAPTQELVERLRERVRVLGTRTPEGLRSLLREELLTL 185 T L+ + P + R+ +V+V TP+G + ++L+ Sbjct: 139 TAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDG--RVDNVQILSA 196 Query: 186 LGTD-FDRAVKT 196 + F+R VK Sbjct: 197 KPANMFEREVKN 208
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 36.6 bits (84), Expect = 2e-04 Identities = 12/36 (33%), Positives = 20/36 (55%) Query: 276 AASGAVAGLVAITPSGGAVSPLGAIAVGAIAGVLCA 311 AA V+ +VA+ S A + LG + + G+LC+ Sbjct: 471 AADAGVSYVVALLFSLLAGTTLGIWGIAIVTGILCS 506
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 29.9 bits (67), Expect = 0.009 Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 11/96 (11%) Query: 130 LERLDIGVCAKKRPHTLLQGQRQRIAVARALAASPSVIFADEPTAALHRADRTHVLRTL- 188 +ER ++G+ P + G ++A + S S +D T R++ Sbjct: 312 VERQNVGISMSVFPVAMAGGNIVLDITSKADSLSSSTQASDVITNQ----------RSIA 361 Query: 189 TSAARSHGITVVLATHDAEVATLADRTVPLLDGRPV 224 T+ G T++L T D VP L P+ Sbjct: 362 TTVNLRDGQTLLLGGLTDYKNTSQDSGVPFLSKIPL 397
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.031 Identities = 12/43 (27%), Positives = 22/43 (51%), Gaps = 4/43 (9%) Query: 170 AAGNTVVIKPSDTTPASTVLIAEIIGQILPKGVFNVICGDRDT 212 +A + +V+K T P + I ++ + + + ICGD DT Sbjct: 89 SASHLIVLK---TMPGNAQAIGALMDNLDWEEIMGTICGD-DT 127
>BLACTAMASEA#Beta-lactamase class A signature. Length = 286 Score = 30.5 bits (69), Expect = 0.011 Identities = 17/51 (33%), Positives = 17/51 (33%), Gaps = 3/51 (5%) Query: 81 RGGSGVHDLESNRPADR---DARFRAGSVTKVFTAAVVLQLAGEGRLDLNR 128 R G DL S R D RF S KV VL G L R Sbjct: 39 RVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLER 89
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 56.4 bits (136), Expect = 2e-11 Identities = 18/115 (15%), Positives = 44/115 (38%), Gaps = 3/115 (2%) Query: 3 IRVVVADDQELVRSGFAMILDAQPDIEVVAEAGDGAAAVDAVRRLGPEVALLDIRMPGTD 62 ++VADD +R+ L ++ +V + A + ++ + D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQAL-SRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GIEACRTINAE-TGCRTVMLTTFDSDEYVYEALHAGASGFLLKDVRRDDLVHAVR 116 + I ++++ ++ +A GA +L K +L+ + Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF06580#Sensor histidine kinase Length = 349 Score = 28.3 bits (63), Expect = 0.049 Identities = 18/90 (20%), Positives = 30/90 (33%), Gaps = 10/90 (11%) Query: 304 IVQEALTNVVRHAAAD-----TVFVQLDYGTGALIITVTDDGCGFAGGV----GMGLIGI 354 +VQ + N ++H A + ++ G + + V + G G GL + Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNV 318 Query: 355 GER-AAAHGGTADTGAGPGGRGFRVRVTIP 383 ER +G A V IP Sbjct: 319 RERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 129 bits (325), Expect = 1e-38 Identities = 77/260 (29%), Positives = 125/260 (48%), Gaps = 11/260 (4%) Query: 3 LTAYDLTGRSAFITGAAGGIGRAGAILLAAAGATVHCADRDEKGLLETRNLIAEAGGTSH 62 + A + G+ AFITGAA GIG A A LA+ GA + D + + L + + + + Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 63 IHTLDVTDPGRIKAAV----AAAGNLDILAAVAGIMHTSSVLETADDDLDRVLSVNFKGV 118 DV D I G +DIL VAG++ + +D++ + SVN GV Sbjct: 61 AFPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 119 LYACQEVARSMIARGAPGSLITMASGAVDAASPGLLCYSAAKAAVVQLTKTLATELGPHS 178 A + V++ M+ R + GS++T+ S + Y+++KAA V TK L EL ++ Sbjct: 121 FNASRSVSKYMMDRRS-GSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 179 IRVNAVAPGWIRTPM-----TARHDAEQQQRAEATMARIS-PLGRVGEPEDVAHTLVYLA 232 IR N V+PG T M + AEQ + + PL ++ +P D+A +++L Sbjct: 180 IRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLV 239 Query: 233 SDASAFMTGQILRPNGGVAM 252 S + +T L +GG + Sbjct: 240 SGQAGHITMHNLCVDGGATL 259
>PF05946#Toxin-coregulated pilus subunit TcpA Length = 199 Score = 30.3 bits (68), Expect = 0.046 Identities = 13/48 (27%), Positives = 24/48 (50%), Gaps = 2/48 (4%) Query: 1366 GVVTRGAVQAEGVEGGFSATYRILSAFEDNGQARRGYV--VEGLGAAQ 1411 G+V+ G + ++ + F T + +F N A + + V+GL AQ Sbjct: 72 GLVSLGKISSDEAKNPFIGTNMNIFSFPRNAAANKAFAISVDGLTQAQ 119
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 26.1 bits (57), Expect = 0.034 Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 5/65 (7%) Query: 44 ALLAALTAQQTFGDGQHLT----LDARGAGLAAAALALVLRAPFLVVVGSAVVVTAGV-R 98 +LLAA + D T L + +G++AAA ++ AP +VG+ + +G+ Sbjct: 352 SLLAAFHKETGAIDASLTTISTVLASVSSGISAAATTSLVGAPVSALVGAVTGIISGILE 411 Query: 99 ALGQA 103 A QA Sbjct: 412 ASKQA 416
>PF07520#Virulence protein SrfB Length = 1041 Score = 29.6 bits (66), Expect = 0.021 Identities = 12/59 (20%), Positives = 25/59 (42%) Query: 5 GTSPLNRAEQFIWLTARALEQRRFAHHFLKGSAEAVETALAAYLNEDGGYGHALEPDLR 63 S L+ ++++W L+ RF +H + A +LNE G ++ ++ Sbjct: 378 TLSGLSSPKRYLWDDDAVLQDWRFQNHHDPNNLPRPVRAAMRHLNEAGDVLAQVKTEIG 436
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.7 bits (59), Expect = 0.037 Identities = 14/51 (27%), Positives = 24/51 (47%), Gaps = 9/51 (17%) Query: 43 ARRLRIWQLAPIVMLAAVGSLMFAFPLAFEFGDGGAV-----VAMLGLLIS 88 A R+R L PI+M + ++ PLA G G + ++G ++S Sbjct: 966 AVRMR---LRPILMTSLA-FILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 30.1 bits (67), Expect = 0.026 Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 310 WYVESIMVHELAHQWFGDSVSPRAWSDLWLN-EGHASWYEARYAE 353 + +E + HE H G V P W EG +WYE AE Sbjct: 494 YTLEELFRHEFTHYLQGRYVVPGMWGQGEFYQEGVLTWYEEGTAE 538
>BINARYTOXINA#Clostridial binary toxin A signature. Length = 454 Score = 32.3 bits (73), Expect = 0.005 Identities = 21/83 (25%), Positives = 35/83 (42%), Gaps = 5/83 (6%) Query: 1 MTSSSSLPQD--AQDAQSATENVTDSLTESLRADALM--EEDVAWSHEIDGERDGEQFDR 56 + +SS P AQD Q A+ +TD D L E + W + + ER + D Sbjct: 16 LILTSSFPSYTYAQDLQIASNYITDRAFIERPEDFLKDKENAIQWEKK-EAERVEKNLDT 74 Query: 57 SERAALRRVAGLSTELEDVTEVE 79 E+ AL S ++ + ++ Sbjct: 75 LEKEALELYKKDSEQISNYSQTR 97
>PF04183#IucA / IucC family Length = 580 Score = 240 bits (615), Expect = 2e-73 Identities = 90/349 (25%), Positives = 122/349 (34%), Gaps = 37/349 (10%) Query: 177 RRAPGAPAEADLFLTAEQSLLLGHPLHPTPKSREGLSESESRLYSPELHGSFPLHWMAVD 236 RR A +L Q LL GHP K R G + Y+PE +F LHW+AV Sbjct: 113 RRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVK 172 Query: 237 RSVLATDSA--------WTDGGRPVSATELITSHAEGLQLPDNTTPIPLHPWQARELGHR 288 R + T P + + L N P+P+HPWQ ++ Sbjct: 173 REHMIWRCDNEMDIHQLLTAAMDPQEFAR-FSQVWQENGLDHNWLPLPVHPWQWQQKIAT 231 Query: 289 PAVTALLDAGLLHDLGPHGKHWHPTSSVRTVHRPGAE--LMLKLSLGVRITNSRRENLRK 346 + A G + LG G W S+RT+ L +KL L + T+ R + Sbjct: 232 DFI-ADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGR 290 Query: 347 ELHRGVEVHRLLRSGLAAQWHAVHPGFDIVRDPAWLAVDGP--------DGEPVAGLDVM 398 + G R L+ A V G I+ +PA V L V+ Sbjct: 291 YIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEMLGVI 350 Query: 399 LRHNPF---GPYDDAVCIAALTAPRPWPGRTGMHSRIAEIVISLAAATGRAVGAVATEWF 455 R NP P + V +A L LA A G A W Sbjct: 351 WRENPCRWLKPDESPVLMATLME----CDENNQ---------PLAGAYIDRSGLDAETWL 397 Query: 456 LRYLDRVVRPVLWLDAHAGVALEAHQQNTLVLLDPHGWPVGGRYRDNQG 504 + VV P+ L GVAL AH QN + + G P +D QG Sbjct: 398 TQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKE-GVPQRVLLKDFQG 445
>PF04183#IucA / IucC family Length = 580 Score = 515 bits (1329), Expect = e-179 Identities = 201/612 (32%), Positives = 284/612 (46%), Gaps = 42/612 (6%) Query: 22 LNRTVWDKAAARLLAKMLGQFAYEEVIEPVRQADGGDTYTLGLDDGGTLSFSARRGVYGS 81 +N WD RL+AKML + YE+V Q D L G F A RG++G Sbjct: 1 MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLP---GAQWRFIAERGIWGW 57 Query: 82 WHIAPDSVRETCGSARESPAESMREGVRGTPAEPLRDRNTDTVPFRDPLQFLARARHILG 141 I ++R EP+ L + + +L Sbjct: 58 LWIDAQTLR--------------------CADEPV-----------LAQTLLMQLKQVLS 86 Query: 142 IDGATLGHLIREITTTLAADARLDHT--ALCADRLADLDYAELEGHQTGHPWLVANKGRL 199 + AT+ ++++ TL D +L L A L +L+ L+ +GHP V NKGR Sbjct: 87 MSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFNKGRR 146 Query: 200 GFSATDASRYAPEARTPVRLPWIAVSTRIAAYRGVTGLATPEQLYVQELDPSVRDSFAAV 259 G+ RYAPE RL W+AV +R + QL +DP F+ V Sbjct: 147 GWGKEALERYAPEYANTFRLHWLAVKREHMIWRCDNEM-DIHQLLTAAMDPQEFARFSQV 205 Query: 260 LRARGLDPGSYLCLPVHPWQWDEWIVPVFAPAIAAGDIVPLHTDADLRLPQQSIRTFTNV 319 + GLD +L LPVHPWQW + I F A G +V L D L QQS+RT TN Sbjct: 206 WQENGLDHN-WLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNA 264 Query: 320 ARPDRHTVKLPLSILNTLVWRGLPTERTLAAPAVTAWVQGLRDRDAFLRDTCQVILLGEV 379 +R +KLPL+I NT +RG+P A P + W+Q + DA L + VIL GE Sbjct: 265 SRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVIL-GEP 323 Query: 380 ASVTVEHPLYDHLPETPYQFKEILGAIWREPLQPRLAPGERARTLASLLHTDPQGRAFTA 439 A+ V H Y L PY+++E+LG IWRE L P E +A+L+ D + Sbjct: 324 AAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAG 383 Query: 440 ELVARSGLTPTAWLTRLFAALLPPLLHFLYRYGTVFSPHGENAIVVFDNQDVPVRLAIKD 499 + RSGL WLT+LF ++ PL H L RYG HG+N + VP R+ +KD Sbjct: 384 AYIDRSGLDAETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKE-GVPQRVLLKD 442 Query: 500 FVDDVNISARPLPEHESMPQDVRRILLTEEPSFLTQFIHAGLFIGVFRFLSPLCEEQLGV 559 F D+ + PE +S+PQ+VR + +L + G F+ V RF+SPL +LGV Sbjct: 443 FQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPL-MVRLGV 501 Query: 560 PEDDFWSLVRAEILRYHARFPELKERFEMFDMLTPRIERLCLNRNRLHVDGYRDRPRRPH 619 PE F+ L+ A + Y + P++ ERF +F + P+I R+ LN +L D R Sbjct: 502 PERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTW-PDLDGGSRML 560 Query: 620 AAIHGTVPNPLH 631 + NPL Sbjct: 561 PNYLEDLQNPLW 572
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 27.8 bits (62), Expect = 0.037 Identities = 11/35 (31%), Positives = 22/35 (62%) Query: 159 VGGEMVVEGEQVVVGDVSSPATEVGYEVLCRRHHR 193 +G + + G+++ + DV++ A VGYE++C R Sbjct: 316 IGTPVELWGKEIKIDDVAAAAGTVGYELMCALALR 350
>PF07132#Harpin protein (HrpN) Length = 356 Score = 60.5 bits (146), Expect = 8e-11 Identities = 52/168 (30%), Positives = 63/168 (37%), Gaps = 7/168 (4%) Query: 209 AAIGGALGGPFALLGGGLGKLLGNLTGKGLGKILGNDAGNVLGKGLAGGGKGAGGAAGGA 268 + +GG LGG LG LG L G L G GLG LG+ G+ LG L GG GA GA A Sbjct: 63 SMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGAGMNA 122 Query: 269 GKAAGGLGKGAGGAGAGGLGKGAGGAGAGAAGKGAGGLGKGAGGAGAGAAGKGAGGLGKG 328 + +G A LG G G G K A +G Sbjct: 123 MNPSAMMGSLLFSALEDLLGGGMSQQQGGLFG------NKQPSSPEISAYTQGVNDALSA 176 Query: 329 AGGAGAGAAGKGAGAAGAGAGKGAGSAGAGAGKGAGAA-GAGLGKGAG 375 G G G G +GAGA G+ G +G+ AG Sbjct: 177 ILGNGLSQTKGQTSPLQLGNNGLQGLSGAGAFNQLGSTLGMSVGQKAG 224 Score = 50.5 bits (120), Expect = 1e-07 Identities = 49/190 (25%), Positives = 66/190 (34%), Gaps = 23/190 (12%) Query: 248 NVLGKGLAGGGKGAGGAAGGAGKAAGGLGKGAGGAGAGGLGKGAGGAGAGAAGKGAGGLG 307 +++ + G GG GG G LG GG GGLG G G + G GG Sbjct: 53 DIMTTMMFMGSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGL 112 Query: 308 KGAGGAGAGAAGKGA-----------GGLGKGAGGAGAGAAGKGAGAAGAGAGKGAGSAG 356 GA GAG A A LG G G G ++ + G Sbjct: 113 GGALGAGMNAMNPSAMMGSLLFSALEDLLGGGMSQQQGGLFGNKQPSSPEISAYTQGVND 172 Query: 357 AGAGKGAGAAGAGLGKGAGAAGDGAAGAGGRAGAGAAGQAISEESARKLGERLGNIMGRT 416 A + G GL + G G G G AG + +LG LG +G+ Sbjct: 173 A----LSAILGNGLSQTKGQTSPLQLGNNGLQGLSGAG------AFNQLGSTLGMSVGQK 222 Query: 417 N--ESLNHVG 424 + LN++ Sbjct: 223 AGLQELNNIS 232
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 26.7 bits (59), Expect = 0.043 Identities = 15/71 (21%), Positives = 28/71 (39%), Gaps = 7/71 (9%) Query: 4 FQEQLAEAMAGLAEQTKKIQQVQEELARASASATSKDRMVTASVNAHGEILSFKFHTEGY 63 F+ ++ + L + T I + EL A + ++ A V+ ++ K HTEG Sbjct: 296 FKNEILDK---LRQTTDNIGLLTLEL--AKNEERQQASVIRAPVS--VKVQQLKVHTEGG 348 Query: 64 RTMPGAQLAEV 74 L + Sbjct: 349 VVTTAETLMVI 359
>cloacin#Cloacin signature. Length = 551 Score = 34.7 bits (79), Expect = 0.001 Identities = 25/87 (28%), Positives = 34/87 (39%), Gaps = 12/87 (13%) Query: 364 AGGDGAGGDGGGTGGKGGGNLDLGAPPPVTGPSGSTSGSNLPKNNN---------LGLGP 414 +GGDG G + G G N G P + G++ GS NN + G Sbjct: 2 SGGDGRGHNTGAHSTSGNIN---GGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGG 58 Query: 415 NPVTGPSGGTSGTGNPPGGGGSLTVPA 441 G GG +G G GG+L+ A Sbjct: 59 GSGHGNGGGNGNSGGGSGTGGNLSAVA 85 Score = 29.7 bits (66), Expect = 0.045 Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 7/61 (11%) Query: 648 NPAAPPTQGNVSTQSLGALGRGGAGGGTGTGTPFMP-------PMGMGGGGAPGGGGNGG 700 N A T GN++ G GGA G+G + P + GGG G GG G Sbjct: 10 NTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNG 69 Query: 701 D 701 + Sbjct: 70 N 70 Score = 29.7 bits (66), Expect = 0.045 Identities = 17/47 (36%), Positives = 20/47 (42%), Gaps = 1/47 (2%) Query: 360 FGNGAGGDGAGGDGGGTGGKGGGNLDLGAPPPVTG-PSGSTSGSNLP 405 G G+G G G G GGNL A P G P+ ST G+ Sbjct: 57 GGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGL 103
>PF05272#Virulence-associated E family protein Length = 892 Score = 35.4 bits (81), Expect = 0.002 Identities = 19/46 (41%), Positives = 27/46 (58%) Query: 686 QGARRVGASAVAGQVVPYRTEWTAPRLPAPDPAPQPVAEEESEESL 731 Q AR G +VAG V+ AP+ P P+P P+PV E+E E++ Sbjct: 92 QVAREEGLESVAGIVMGAPAGAPAPKPPRPEPPPRPVVEKECWETI 137
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 129 bits (326), Expect = 6e-36 Identities = 77/304 (25%), Positives = 125/304 (41%), Gaps = 20/304 (6%) Query: 107 QVPWAQSFLGIDRAWELSRGAGVKVAVIGTGADLRRVPALDGRVTGGPDVVAGGT----V 162 ++P + W +RG GVKVAV+ TG D P L R+ GG + + Sbjct: 21 EIPRGVEMIQAPAVWNQTRGRGVKVAVLDTGCDADH-PDLKARIIGGRNFTDDDEGDPEI 79 Query: 163 RDDCVGYGTFLAGIVAGGQQQGLEAAGVAPEAEVIAVRATSKQGATTPEALAKGIRAATG 222 D G+GT +AG +A + GVAPEA+++ ++ +KQG+ + + +GI A Sbjct: 80 FKDYNGHGTHVAGTIAATEN-ENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIE 138 Query: 223 SGAQIIHVALSVPSAPKQLKDAVLAAQKAGALVVAPASAREWESGAGASQAENGPAYPAA 282 II ++L P +L +AV A + LV+ A G G + + YP Sbjct: 139 QKVDIISMSLGGPEDVPELHEAVKKAVASQILVMCAA----GNEGDGDDRT-DELGYPGC 193 Query: 283 LPGVLAVSSVGPGGEPEAPGTGKGRRSQPRLSAPGVSVTGPGPGGRGQFTGRGDAVAGAF 342 V++V ++ ++ L APG + PGG+ G ++A Sbjct: 194 YNEVISVGAINFDRH---ASEFSNSNNEVDLVAPGEDILSTVPGGKYATFS-GTSMATPH 249 Query: 343 VAGTAALVLS-----YHPRLTAEQVAHRLESTAYGAVGDTPDPRIGLGIVDPVRALSAVL 397 VAG AL+ + LT ++ +L GL + V LS + Sbjct: 250 VAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKMEGNGLLYLTAVEELSRIF 309 Query: 398 PEER 401 +R Sbjct: 310 DTQR 313
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.4 bits (68), Expect = 0.049 Identities = 17/62 (27%), Positives = 24/62 (38%), Gaps = 6/62 (9%) Query: 606 LVFAGPPGTGKTTVARLYGSILASLGVLRSGHLVEVSRADLVAQIIGGTAIKTTE--TFN 663 +V G G GK+T+ L L H + D QI G A + +E F Sbjct: 599 VVLEGTGGIGKSTLIN----TLVGLDFFSDTHFDIGTGKDSYEQIAGIVAYELSEMTAFR 654 Query: 664 KA 665 +A Sbjct: 655 RA 656
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.3 bits (70), Expect = 0.005 Identities = 19/74 (25%), Positives = 27/74 (36%), Gaps = 3/74 (4%) Query: 215 PATSTDPGQERTPGQESGATPGTDSQGGQSRNPDSGQGDGSSADPVPSPTPSDNTGGQTN 274 P PG P + P + NP + G+ +P P P + + T+ Sbjct: 311 PRPDLTPGSAEAPNAQP--LPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDANPDTD 368 Query: 275 PPPATTP-SPAAPG 287 P T P SPA P Sbjct: 369 GQPGTRPDSPAVPD 382 Score = 29.3 bits (65), Expect = 0.023 Identities = 23/74 (31%), Positives = 33/74 (44%), Gaps = 18/74 (24%) Query: 233 ATPGTDSQGGQSRN------PD--SGQGDGSSADPVP----------SPTPSDNTGGQTN 274 AT G DSQG + + PD G + +A P+P +P P++N G + N Sbjct: 293 ATFGRDSQGNTTVDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPN 352 Query: 275 PPPATTPSPAAPGD 288 P P +P A D Sbjct: 353 PEPDPDLNPDANPD 366
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.9 bits (114), Expect = 4e-08 Identities = 73/321 (22%), Positives = 126/321 (39%), Gaps = 36/321 (11%) Query: 28 LSMMGIGVV-----TMVSQLTGRYGLA---GALSATLAMSAAVIGPLISRLVDRHGQRRV 79 L +GIG++ ++ L + G L A A+ P++ L DR G+R V Sbjct: 16 LDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPV 75 Query: 80 LRPATLVALAAVAGLLICAQQRLADWTLFVFAAGAGCVPSVGSMIRARWAEIYRGSPRQL 139 L + +A AAV ++ L W L++ AG + G++ A A+I G R Sbjct: 76 LLVS--LAGAAVDYAIMATAPFL--WVLYIGRIVAGITGATGAVAGAYIADITDGDERAR 131 Query: 140 HTAYSWESIVDEVCFIFGPIISIGLSTAWFPEAGPLLAAGFL-----LVGVFWLTAQRAT 194 H + + S + GP++ GL + P A P AA L L G F L Sbjct: 132 H--FGFMSACFGFGMVAGPVLG-GLMGGFSPHA-PFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 195 EPVPHPREQHTRGSALRS----RGLQVLVVTFVATGAIFGAIDVVTVAFAEEQGHKAAAS 250 E P RE ++ R + L+ F + + V F E++ H A + Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT 247 Query: 251 LVLAVYALGSCLAGAVFGLLHLKGKPSTRW------LVGVCAMAVSMIPLQLAGNLP--F 302 + +++ A G + ++ + + G + R ++G+ A I L A F Sbjct: 248 IGISLAAFG--ILHSLAQAM-ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAF 304 Query: 303 LAVALFVAGLAIAPTMVTTMA 323 + L +G P + ++ Sbjct: 305 PIMVLLASGGIGMPALQAMLS 325
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 75.6 bits (186), Expect = 3e-18 Identities = 35/119 (29%), Positives = 54/119 (45%), Gaps = 1/119 (0%) Query: 2 RVLVVEDEQLLADAVATGLRREAMAVDVVYDGAAALERVEVNDYDVVVLDRDLPLVHGDD 61 +LV +D+ + + L R V + + A + D D+VV D +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VCRRIVELGMPTRVLMLTASGDVSDRVEGLELGADDYLPKPFAFTELTARV-RALGRRT 119 + RI + VL+++A ++ E GA DYLPKPF TEL + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 3e-04 Identities = 22/104 (21%), Positives = 40/104 (38%), Gaps = 23/104 (22%) Query: 310 LVQNAVRYNV---PEGGWVEVTTEPRSGQAVLVVSNTGPVVPAYEIDNLFEPFRRLRTER 366 LV+N +++ + P+GG + + +G L V NTG L + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS----------------LALKN 306 Query: 367 TGSDKGVGLGLSIARSVARAHGG--RIVAEPREGGGLVMRVSLP 408 T G GL ++ + +G +I ++G V +P Sbjct: 307 TKESTGTGL-QNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>PF06580#Sensor histidine kinase Length = 349 Score = 37.2 bits (86), Expect = 2e-04 Identities = 22/119 (18%), Positives = 43/119 (36%), Gaps = 28/119 (23%) Query: 720 VDVDPGLLERAVAN-----IVENAVKY--SPCAE--RVTVAASALGGRVELRVADRGPGV 770 ++P +++ V +VEN +K+ + + ++ + + G V L V + G Sbjct: 244 NQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA 303 Query: 771 PDDAKERIFEPFQRYGDAPRGAGVGLGLAVARGFVESMGG---TLGAEDTPGGGLTMVL 826 + KE G GL R ++ + G + + G MVL Sbjct: 304 LKNTKE--------------STGTGLQNVRER--LQMLYGTEAQIKLSEKQGKVNAMVL 346
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 96.1 bits (239), Expect = 4e-25 Identities = 35/120 (29%), Positives = 64/120 (53%), Gaps = 1/120 (0%) Query: 2 TRVLVVDDEPQIVRALVINLKARKYEVDAAPDGATALQLAAARHPDVVVLDLGLPDMDGV 61 +LV DD+ I L L Y+V + AT + AA D+VV D+ +PD + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 EVIKGLR-GWTRVPILVLSARHTSDEKVEALDAGADDYVTKPFGMDELLARLRASVRRAE 120 +++ ++ +P+LV+SA++T ++A + GA DY+ KPF + EL+ + ++ + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.8 bits (67), Expect = 0.007 Identities = 12/31 (38%), Positives = 20/31 (64%), Gaps = 1/31 (3%) Query: 1 MRVAIAG-AGAVGRSIAGELLENGHEVLLVD 30 M+ + G AG +G ++ LLE GH+V+ +D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGID 31
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.011 Identities = 10/31 (32%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 1 MHIVIMG-CGRVGAALAQTLEQQGHTVAVID 30 M ++ G G +G +++ L + GH V ID Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGID 31
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 41.2 bits (96), Expect = 3e-05 Identities = 45/265 (16%), Positives = 90/265 (33%), Gaps = 16/265 (6%) Query: 744 AREQARRTRIGELHVEREALEAEREQLAEALRAVTGRREELDAELAAVPGDDDLRHAHAR 803 AR+ + A A+ + L A+ R+ EL+ L + A+ Sbjct: 155 ARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA--MNFSTADSAK 212 Query: 804 VTAAADALQRARARQRERAAELDRAADEADHTATELSE-TAAAMNLPTDREGLASVHQAL 862 + AR+ + L+ A + + + ++ A L + L + Sbjct: 213 IKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGA 272 Query: 863 ADHTAHLAALWPALR---ERADAEHAVTGDQAETGRAELLVSELTERTTEAARRAASADE 919 + + +A L +AE A Q++ A + R +A+R A E Sbjct: 273 MNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNANR---QSLRRDLDASREAKKQLE 329 Query: 920 ----HLRTLRSTVGAAVAELQRRLEETAGAARVCESEQQRAQADLRDADRRASHAEGRIE 975 L A+ L+R L+ + A + E+E Q+ + + ++ ++ Sbjct: 330 AEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLD 389 Query: 976 RLNED---VTDATAARERAVAALQR 997 E V A +AAL++ Sbjct: 390 ASREAKKQVEKALEEANSKLAALEK 414 Score = 36.6 bits (84), Expect = 8e-04 Identities = 33/135 (24%), Positives = 60/135 (44%), Gaps = 4/135 (2%) Query: 744 AREQARRTRIGELHVEREALEAEREQLAEALRAVTGRREELDAELAAVPGDDDLRHAHAR 803 A + A +L + + L A R+ L L A +++L+AE + + + A +R Sbjct: 288 AEKAALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEA-SR 346 Query: 804 VTAAADALQRARARQRERAAELDRAADEADHTATELSETAAAMNLPTDREGLASVHQALA 863 + D L +R +++ AE + E + +E S + +L RE V +AL Sbjct: 347 QSLRRD-LDASREAKKQLEAEHQKL--EEQNKISEASRQSLRRDLDASREAKKQVEKALE 403 Query: 864 DHTAHLAALWPALRE 878 + + LAAL +E Sbjct: 404 EANSKLAALEKLNKE 418
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 50.6 bits (121), Expect = 1e-09 Identities = 33/174 (18%), Positives = 62/174 (35%), Gaps = 17/174 (9%) Query: 2 RIDVVIADDQQLVRAGFRMILEAQPGIDVVGEAADGVECVDLARRLRPQVVLADIRMPRL 61 +++ADD +R L + G DV ++ +V+ D+ MP Sbjct: 3 GATILVADDDAAIRTVLNQALS-RAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGLEVTRQLAGPGVADPMNVVVITTFDQDDYVRTALRNGACGFLLKDATPALLVEAVHAA 121 + ++ ++ P V+V++ + A GA +L K P L E + Sbjct: 61 NAFDLLPRIKKARPDLP--VLVMSAQNTFMTAIKASEKGAYDYLPK---PFDLTELIGII 115 Query: 122 ARGDALVSPAVTVRLLKRLEQAELGTASGGAEAFGLSGRELDIVRLVA-VGRTN 174 R + KR + G G S +I R++A + +T+ Sbjct: 116 GR---------ALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTD 160
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 53.3 bits (128), Expect = 3e-09 Identities = 32/153 (20%), Positives = 60/153 (39%), Gaps = 9/153 (5%) Query: 181 IGFALAAVILVMTFGSLIAAGLPLLTAVVGVGVSIAAIKALSATFDLNSNTSALATM-LG 239 L +++ + ++ A +P + V + + A + A F + NT + M L Sbjct: 346 EAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAA----FGYSINTLTMFGMVLA 401 Query: 240 IAVGIDYALFIVSR-YRSERAAGYGAGEAAARANGTAGSAVVFAGLTVVIA---LAGLAV 295 I + +D A+ +V R EA ++ A+V + + +A Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGG 461 Query: 296 VNLPILTAMGLAAGGAVVIAVLVAVTLVPALLA 328 I + A+ ++VLVA+ L PAL A Sbjct: 462 STGAIYRQFSITIVSAMALSVLVALILTPALCA 494 Score = 49.8 bits (119), Expect = 3e-08 Identities = 32/170 (18%), Positives = 66/170 (38%), Gaps = 23/170 (13%) Query: 530 ALVVGLAVLVLILVFRSVLVPLKAALGFLLSVLAALGALVAVFQWGWLKDLVGLDQTGPI 589 ++V L + + + R+ L+P A + LG + +G+ + Sbjct: 348 IMLVFLVMYLFLQNMRATLIPTIAV------PVVLLGTFAILAAFGY---------SINT 392 Query: 590 MSLMPILMVGIVFGLAMDYQVFLVTRM-REAYVNGADARTAIESGFRHSAKVVTAAALIM 648 +++ ++ + GL +D + +V + R + + A E + A+++ Sbjct: 393 LTMFGMV---LAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVL 449 Query: 649 IAVF---AGFVGSQDAMLKSMGFGLAIAVFFDAFIVRMTIVPAALALLGK 695 AVF A F GS A+ + + A+ V + + PA A L K Sbjct: 450 SAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVL-VALILTPALCATLLK 498 Score = 32.9 bits (75), Expect = 0.005 Identities = 36/194 (18%), Positives = 68/194 (35%), Gaps = 10/194 (5%) Query: 150 DALADGRDRGLTIEASGDALAAPEGSASAEA-IGFALAAVILVM--TFGSLIAAGLPLLT 206 + LA G+ + +G + A A + + V L + + S +L Sbjct: 844 ENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLV 903 Query: 207 AVVGVGVSIAAIKALSATFDLNSNTSALATMLGIAVGIDYALFIVSRYRSERAA-GYGAG 265 +G+ + + A + N + + I + A+ IV + G G Sbjct: 904 VPLGI---VGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 266 EAAARANGTAGSAVVFAGLTVVIALAGLAVVNLP---ILTAMGLAAGGAVVIAVLVAVTL 322 EA A ++ L ++ + LA+ N A+G+ G +V A L+A+ Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 323 VPALLAFAPERVRG 336 VP +G Sbjct: 1021 VPVFFVVIRRCFKG 1034
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 159 bits (404), Expect = 6e-51 Identities = 55/197 (27%), Positives = 87/197 (44%), Gaps = 13/197 (6%) Query: 24 LFPGEAELIRNSVEGRRKEFTTARWCARRALGELGVAPAPILKGERGAPIWPGGVVGSMT 83 L+ + +R++ R+ E R A AL E+GV P + G++ P+WP G+ GS++ Sbjct: 31 LWLPHHDRLRSAGRKRKAEHLAGRIAAVHALREVGVRTVPGM-GDKRQPLWPDGLFGSIS 89 Query: 84 HCAGYRAAAVARRADVLTVGIDAEPHEALPDGVHESIALATELQRELELRRTWPEIHWDR 143 HCA A ++R+ +GID E + + ++ +R++ P Sbjct: 90 HCATTALAVISRQ----RIGIDIEKIMSQHTATELAPSIIDSDERQILQASLLPFPLALT 145 Query: 144 LLFSAKESVYKAWFPLTHRWLGFEQADIVLHSNGSFTAGLLISTMEPDLAAGATATPTAF 203 L FSAKESVYKA+ GF A + + + LL P AA A T Sbjct: 146 LAFSAKESVYKAF-SDRVTLPGFNSAKVTSLTATHISLHLL-----PAFAAT-MAERT-V 197 Query: 204 SGRWLVADGLMVTAIVA 220 W D ++T + A Sbjct: 198 RTEWFQRDNSVITLVSA 214
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.7 bits (90), Expect = 1e-05 Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 4/84 (4%) Query: 2 RVVIAEDNVLLSNGLELLLTAKGFHVAAITQDAPGFVAAVTEHRPDVTIVDVRLPPTFRD 61 +++A+D+ + L L+ G+ V T +A + D+ + DV +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMP---DE 60 Query: 62 EGIHAAIHARRQHPGLPVLVLSQY 85 ++ P LPVLV+S Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQ 84
>PF06580#Sensor histidine kinase Length = 349 Score = 42.5 bits (100), Expect = 1e-06 Identities = 11/67 (16%), Positives = 28/67 (41%), Gaps = 6/67 (8%) Query: 318 RTTVRVAREGDRLSIEVTDDGVGGADETL---GTGIAGIRHRVLAL---DGTVHIHSPSG 371 + ++ ++ +++EV + G T GTG+ +R R+ L + + + G Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339 Query: 372 GPTTITV 378 + + Sbjct: 340 KVNAMVL 346
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 41.5 bits (97), Expect = 1e-07 Identities = 16/72 (22%), Positives = 25/72 (34%), Gaps = 1/72 (1%) Query: 32 PRRCSHRRHAARARLL-TADELFCAEGVRSVRIDRVIAHAGAAKATLYNAFGTKDGLVRA 90 R+ R +L A LF +GV S + + AG + +Y F K L Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 91 YLQARHAATAEH 102 + + E Sbjct: 62 IWELSESNIGEL 73
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 36.3 bits (84), Expect = 9e-06 Identities = 24/89 (26%), Positives = 32/89 (35%), Gaps = 12/89 (13%) Query: 16 LVTGVTSGIGRAVAKRLAADGMSVVV-----AGRNARRGAETVKEITTDGGRARFVEADL 70 LVTG IG V+KRL G VV + ++ + G +F + DL Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPG--FQFHKIDL 61 Query: 71 EDPAGIDRLAAEVGCS-----ASRSGRRY 94 D G+ L A R RY Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRY 90
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (263), Expect = 2e-29 Identities = 73/256 (28%), Positives = 118/256 (46%), Gaps = 15/256 (5%) Query: 20 GLRGKSFLVTGGSRGLGYAVTRVLVAEGASVAI--CGRDADTLARASSELRRDFDAQVVT 77 G+ GK +TG ++G+G AV R L ++GA +A + +S + Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF-- 62 Query: 78 GAVDVLAPDELEDFTRQAGRELGGLDGLVANIGGKRGSGLLDS-TREDWQATWELNGGHA 136 DV +++ T + RE+G +D LV N+ G GL+ S + E+W+AT+ +N Sbjct: 63 -PADVRDSAAIDEITARIEREMGPIDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGV 120 Query: 137 VRTVRSALDSL--RPGGSVVIVASISGWKPRFP-AQYGAAKASEIYLAGALCQELAPYGV 193 RS + R GS+V V S PR A Y ++KA+ + L ELA Y + Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 194 RVNTVSPGS--ILLPGKSW---DRLRRRDSATYEAYAERNPNGRLLNADEVARVIAFLLS 248 R N VSPGS + W + + + E + P +L ++A + FL+S Sbjct: 181 RCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVS 240 Query: 249 PASGAVNGAHIPVDGG 264 +G + ++ VDGG Sbjct: 241 GQAGHITMHNLCVDGG 256
>PF06580#Sensor histidine kinase Length = 349 Score = 37.9 bits (88), Expect = 5e-05 Identities = 16/87 (18%), Positives = 32/87 (36%), Gaps = 12/87 (13%) Query: 343 LLTNAAKHA-----RADRVWIDIRHEREALRISVGDDGCGGATV---SAGTGLGGIESRI 394 L+ N KH + ++ + + + + V + G S GTGL + R+ Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKESTGTGLQNVRERL 322 Query: 395 AAF---DGVLSVNSPQGGPTMTTMEIP 418 + + ++ QG + IP Sbjct: 323 QMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 40.6 bits (95), Expect = 2e-06 Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 4/84 (4%) Query: 2 RIVLAEDLFLLREGLVRLLTAHGFEIAAAVDNGPELLDATVEHRPDVALVDVRLPPTFTD 61 I++A+D +R L + L+ G+++ N L D+ + DV +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPD---E 60 Query: 62 EGLRAAIEARRRIPGLPVLVLSQY 85 ++ P LPVLV+S Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQ 84
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 42.1 bits (99), Expect = 7e-06 Identities = 33/159 (20%), Positives = 56/159 (35%), Gaps = 13/159 (8%) Query: 506 VVIPLVLVVVFVILIALLRAVVAPVLLMATVVLSYFAALGISWQLFQHVLGFPAVDTQVM 565 ++ + VVVF+ L AL + PV +M V L L + LF Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAAT-LFNQKNDVYF------ 926 Query: 566 LIGFLFLVALGVDYNIFLIHRIREDVGHHGH--RSGVL-SGLTSTGGVITGAGAVLAATF 622 ++G L + L I ++ ++ + G L + ++ + A + Sbjct: 927 MVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVL 986 Query: 623 --AALTSAPQVAFIEIGIVVAIGVLIDTFLVRSVLVPAL 659 A A A +GI V G++ T L VP Sbjct: 987 PLAISNGAGSGAQNAVGIGVMGGMVSATLLAI-FFVPVF 1024 Score = 32.1 bits (73), Expect = 0.009 Identities = 20/121 (16%), Positives = 36/121 (29%), Gaps = 26/121 (21%) Query: 564 VMLIGFLFLVALGVDYNIFL---------------------IHRIREDVGHHGHRSGVLS 602 V+L F L A G N + R+ + + Sbjct: 375 VLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME-DKLPPKEATEK 433 Query: 603 GLTSTGGVITGAGAVLAATF---AALTSAPQVAFIEIGIVVAIGVLIDTFLVRSVLVPAL 659 ++ G + G VL+A F A + + + I + + + + L PAL Sbjct: 434 SMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALI-LTPAL 492 Query: 660 A 660 Sbjct: 493 C 493
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 57.7 bits (139), Expect = 2e-12 Identities = 30/189 (15%), Positives = 63/189 (33%), Gaps = 19/189 (10%) Query: 7 RRVRRTHRALRAALVDLVLEKGFHALSVEEIAERADVARATFYAHYRDKEDLLLGIVRDL 66 + + T + + + L ++G + S+ EIA+ A V R Y H++DK DL I Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI---W 63 Query: 67 AEDRERLLPAVEQAQAQGFTGLP------VLYIFRHAEQE---RRVYQVILRG------- 110 + + QA+ ++++ E R + ++I Sbjct: 64 ELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEM 123 Query: 111 EGDGRALREFSAIICKRVETVFRERAAQLGVTPRIPFDVIARAWTGELIGVLTWWVENDT 170 +A R R+E + + + A G + G++ W+ Sbjct: 124 AVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQ 183 Query: 171 GYSAAEITG 179 + + Sbjct: 184 SFDLKKEAR 192
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 38.3 bits (89), Expect = 5e-05 Identities = 33/161 (20%), Positives = 71/161 (44%), Gaps = 10/161 (6%) Query: 23 RYNSRRAWLITALIVAFMVINYADKSVLGLAAVPIMDELHISNSTYGLISSSFYLLFSLS 82 R+N WL ++ F V+N + VL ++ I ++ + ++ ++++F L FS+ Sbjct: 11 RHNQILIWL--CILSFFSVLN---EMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIG 65 Query: 83 GLLVGFASSRIS-SRMLLFTLTVLWAVAQLPVLFVAAVPTLIAGRVLLGAAEGPAAPMSM 141 + G S ++ R+LLF + + + + + + LI R + GA + M Sbjct: 66 TAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVM 125 Query: 142 HALYKWFPTTRR----GLPSALQIGGAALGTLISAPLLTWL 178 + ++ P R GL ++ G +G I + ++ Sbjct: 126 VVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI 166
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 55.4 bits (133), Expect = 8e-12 Identities = 25/166 (15%), Positives = 56/166 (33%), Gaps = 7/166 (4%) Query: 2 AERREELLRAAVEQIEVRGVAAVRIADVAAVLGVSNALVLYHFSTKEKLVAAAFAHAAEA 61 E R+ +L A+ +GV++ + ++A GV+ + +HF K L + + + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 62 DLAHLRKLLSRRTSAVR-RLRAAVRWY-APTGQAKGWRLWIEGWAASLRD----PALRNV 115 + ++ LR + T + RL +E ++ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 116 AGDLDQQWKAELAEVIEEGAAAGEFHCD-DPMSVAWRLTALLDGLA 160 +L + + + ++ A D A + + GL Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 208 bits (531), Expect = 5e-62 Identities = 103/312 (33%), Positives = 153/312 (49%), Gaps = 39/312 (12%) Query: 201 TLDKSVPQIGADRAHRAGITGKGTRVAVLDTGYDRDHPDLKSAVVASQDFTEDGD----- 255 + + V I A G+G +VAVLDTG D DHPDLK+ ++ ++FT+D + Sbjct: 21 EIPRGVEMIQAPAVWNQT-RGRGVKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEI 79 Query: 256 VQDMQGHGTHVSSIIAGSGAASEGRYAGVAPGAELVEGKVLNNDGYGYDSWILAGMQWAV 315 +D GHGTHV+ IA + + GVAP A+L+ KVLN G G WI+ G+ +A+ Sbjct: 80 FKDYNGHGTHVAGTIAATENENGV--VGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAI 137 Query: 316 DQDVKVVNMSLGSRVASDGTDPLSAAVDKLSAEHGTLFVIAAGNSGD-----RTISAPGA 370 +Q V +++MSLG + L AV K L + AAGN GD + PG Sbjct: 138 EQKVDIISMSLGG---PEDVPELHEAVKKA-VASQILVMCAAGNEGDGDDRTDELGYPGC 193 Query: 371 ADAALTVGSVTKSGEMSAFTSRGPRQGRPAVKPEISAPGSDIVAARAAGTLDDAAVTERY 430 + ++VG++ S F++ + ++ APG DI++ G Y Sbjct: 194 YNEVISVGAINFDRHASEFSNSNN-------EVDLVAPGEDILSTVPGGK---------Y 237 Query: 431 ASLSGTSMASPHVAGAAALLAQR-----HPDWSGARLKAALIGSAAPVDGATVSDTGSGL 485 A+ SGTSMA+PHVAGA AL+ Q D + L A LI P+ + G+GL Sbjct: 238 ATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSP-KMEGNGL 296 Query: 486 TDVPAALAAAVV 497 + A + + Sbjct: 297 LYLTAVEELSRI 308
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 42.3 bits (99), Expect = 3e-07 Identities = 24/184 (13%), Positives = 53/184 (28%), Gaps = 13/184 (7%) Query: 3 RAGLTTERVVEAAADLADSIGFDKVTISALARGFGVKDASLYSHVRNLHDLRTRVALLAA 62 A T + +++ A L G ++ +A+ GV ++Y H ++ DL + + L+ Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 63 GEFIDRIAAAVAGRAGKDALVAFADAYRAFALERPGRYEATQMRIDPAVAARSSAYHRTI 122 + A G V + R+ + + + Sbjct: 68 SNIGELELEYQAKFPGDPLSVLREILIHVLES----TVTEERRRLLMEIIFHKCEFVGEM 123 Query: 123 ETTGAMLRAYGLAEPDLTDAVRLLRSTFHGYCALEASGGFGAPRDVQTSWERSVGALHFL 182 R + L+ + A + + G + L Sbjct: 124 AVVQQAQRNL--CLESYDRIEQTLK-------HCIEAKMLPADLMTRRAAIIMRGYISGL 174 Query: 183 LEHW 186 +E+W Sbjct: 175 MENW 178
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 0.002 Identities = 22/99 (22%), Positives = 31/99 (31%), Gaps = 1/99 (1%) Query: 226 APKAGSKTGSTPAAQPKTAPRQKAKPRHQTTEPKQQPATSQHQAAKPRHQTTEPKQRPAT 285 AP S+T T A K + K TE Q + AK + A Sbjct: 1029 APATPSETTETVAENSKQESKTVEKNEQDATETTAQ-NREVAKEAKSNVKANTQTNEVAQ 1087 Query: 286 SQHQAAKPQHRTTEPKQHPEKAESHKPQRAEKHSDTLVA 324 S + + Q T+ EK E K + + V Sbjct: 1088 SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVT 1126 Score = 31.6 bits (71), Expect = 0.008 Identities = 16/91 (17%), Positives = 29/91 (31%), Gaps = 5/91 (5%) Query: 242 KTAPRQKAKPRHQTTEPKQQPATSQHQAAKPRHQTTEPKQRPATSQHQAAKPQHR----- 296 +T + + E K + T + Q PKQ + + A+P Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTV 1153 Query: 297 TTEPKQHPEKAESHKPQRAEKHSDTLVAPVA 327 + Q + Q A++ S + PV Sbjct: 1154 NIKEPQSQTNTTADTEQPAKETSSNVEQPVT 1184
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 31.1 bits (70), Expect = 0.006 Identities = 18/90 (20%), Positives = 25/90 (27%) Query: 298 ADAEPGVGGIVEPAVDPARPAETQKVVILPEPAPPTPAAAVETIAETFSAAPVMPLERRL 357 EP V EP P P E V+ P+P P V+ + + + Sbjct: 68 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPAS 127 Query: 358 GQVEFGPGRSPHSGTAARRGGVSAEPAAPA 387 P R S A A+ Sbjct: 128 PFENTAPARPTSSTATAATSKPVTSVASGP 157
>PF06580#Sensor histidine kinase Length = 349 Score = 43.7 bits (103), Expect = 1e-06 Identities = 19/119 (15%), Positives = 36/119 (30%), Gaps = 20/119 (16%) Query: 401 LPEPTGDATALSMVWQNLIGNAVK--FRRPDVPCRITVGCVRDGDDWHFSVADNGIGIAP 458 + D M+ Q L+ N +K + +I + +D V + G Sbjct: 246 INPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG----- 300 Query: 459 EFSQKVFVIFQRLHGREQYEGTGIGLA-LCRKIVEFHGGRIWLDPEAAEG-TCVRFTLP 515 L + E TG GL + ++ +G + +G +P Sbjct: 301 -----------SLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 55.6 bits (134), Expect = 1e-10 Identities = 30/136 (22%), Positives = 57/136 (41%), Gaps = 4/136 (2%) Query: 44 ILLVEDDAGDALLVEEMLADSELDSALTWCRTLTEARRFLAGCRTPCCVLLDLHLSDVYG 103 IL+ +DDA ++ + L+ + D + R++A V+ D+ + D Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWIAA-GDGDLVVTDVVMPDENA 62 Query: 104 LDAVTQIVESAPDAAIVVLTGRAEADTGLSAVATGAQDYLVKGRLDPEALGRSVRYALQR 163 D + +I ++ PD ++V++ + T + A GA DYL K D L + AL Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKP-FDLTELIGIIGRALAE 121 Query: 164 KQVERAAAALRANRLM 179 + + + M Sbjct: 122 PKRRPSKLEDDSQDGM 137
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 36.6 bits (84), Expect = 1e-04 Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 4/91 (4%) Query: 153 LTGRRALLTGGRAKIGMYIGLRLLRDGAHTTITTRFPNDAIRRFKAMPDSDEWIHRLKIV 212 + G+ A +TG IG + L GAH P + ++ Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP-- 63 Query: 213 GIDLRDPAQVVALADSVAAE-GPLDILINNA 242 D+RD A + + + E GP+DIL+N A Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVA 93
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 34.2 bits (78), Expect = 3e-04 Identities = 12/36 (33%), Positives = 20/36 (55%) Query: 6 ALSAVPRLVGSAVVGALIGAVVGVLTNTPLGILAGI 41 L++V + +A +L+GA V L GI++GI Sbjct: 374 VLASVSSGISAAATTSLVGAPVSALVGAVTGIISGI 409
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 29.7 bits (66), Expect = 0.031 Identities = 22/159 (13%), Positives = 50/159 (31%), Gaps = 28/159 (17%) Query: 79 EEGLAALTCGAFHIRSGGRAYFNTTPLGRAVTGTLLVRAMLEDNVQIWGDGSTFKGNDIE 138 EEG A A R+ G + G + R L + + + Sbjct: 533 EEGTAEFF--AGSTRTDGIKPRKSVTQG--LAYDRNNRMSLYGVLH-----AKYGSW--- 580 Query: 139 RFYRYGLLA-----NPHLRIYKPWLD----------ADFVTELGGRKEMSEWLLAHDLPY 183 FY YG N ++ ++ + D++ + +++ + Sbjct: 581 DFYNYGFALSNYMYNNNMGMFNKMTNYIKNNDVSGYKDYIASMSSDYGLNDKYQDYMDSL 640 Query: 184 RDSTEK-AYSTDANIWGATHEAKTLEHLDTGVETVEPIM 221 ++ + ++ + HEAK + + ++ V I Sbjct: 641 LNNIDNLDVPLVSDEYVNGHEAKDINEITNDIKEVSNIK 679
>PF06580#Sensor histidine kinase Length = 349 Score = 37.9 bits (88), Expect = 6e-05 Identities = 14/59 (23%), Positives = 22/59 (37%), Gaps = 2/59 (3%) Query: 330 ERLTITVEDDGRTGGNHAHPGTGHGLIGMRERASTVGGCLYA--GERPEGGFTVTAELP 386 +T+ VE+ G + TG GL +RER + G +G +P Sbjct: 290 GTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.9 bits (158), Expect = 2e-14 Identities = 25/118 (21%), Positives = 43/118 (36%), Gaps = 4/118 (3%) Query: 3 IRVLLADDQALLRGTFRMLFDSTDDMETVGEASNGQEALELARAERPHVVLMDIRMPEMD 62 +L+ADD A +R + V SN A +V+ D+ MP+ + Sbjct: 4 ATILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLDATRLISESEDLSAVKVLILTTFEDDEHVAEALRAGASGFLGKGARPEELLDAVRT 120 D I + + VL+++ +A GA +L K EL+ + Sbjct: 62 AFDLLPRI--KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117