>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 27.0 bits (59), Expect = 0.004 Identities = 16/46 (34%), Positives = 18/46 (39%), Gaps = 4/46 (8%) Query: 11 PDRPAGWHGPRGL----GTAACFMRTGIWVADRIPGSLPLTDILLP 52 PDRP G H G C I DR+P P D+ LP Sbjct: 381 PDRPNGRHRKERKEGEDGGLLCKFFPDILACDRLPEPNPAEDLNLP 426
>PRTACTNFAMLY#Pertactin virulence factor family signature. Length = 910 Score = 73.9 bits (181), Expect = 3e-15 Identities = 155/683 (22%), Positives = 226/683 (33%), Gaps = 117/683 (17%) Query: 727 GSSISGG---GKVVQKGSGT----TTFTGNNTYSGGLTVEQGTAEAGIADNAFGSGPLTV 779 G I+GG G +G+ T + +GG V G G FG G Sbjct: 232 GGHITGGRAAGVAAMQGAVVHLQRATIRRGDAPAGGA-VPGGAVPGGAVPGGFGPGGFGP 290 Query: 780 Q---------AGAKADLHDFNTSVGGLIGAGDVTLGSGTLTVNQGFDSIFSGVISGDGGL 830 +G+ +L L A V G+ +TV+ G S G + GG Sbjct: 291 VLDGWYGVDVSGSSVELAQSIVEAPELGAAIRVGRGA-RVTVSGGSLSAPHGNVIETGGA 349 Query: 831 NKSGAGQLTLS-----GANTYGGA-----------TTIDGGVLLQGE--------SGAFS 866 + LS GA+ G A T+ GG QG+ S Sbjct: 350 RRFAPQAAPLSITLQAGAHAQGKALLYRVLPEPVKLTLTGGADAQGDIVATELPSIPGTS 409 Query: 867 SSSAYRTGASGTVDLGGFDT-NMASLDNAGLVNFGGTGCATLHIAD-------------- 911 AS G + S+DNA V + L +A Sbjct: 410 IGPLDVALASQARWTGATRAVDSLSIDNATWVMTDNSNVGALRLASDGSVDFQQPAEAGR 469 Query: 912 ------NYVGHNGIVAINTVLGDDNSLTDMLKVEGNTSGTTSLKVINRGGVGMQTANGIK 965 N + +G+ +N D L+D L V + SG L V N G +AN + Sbjct: 470 FKVLTVNTLAGSGLFRMNVFA--DLGLSDKLVVMQDASGQHRLWVRNSGS-EPASANTLL 526 Query: 966 VVEVVGQSDGVFSLLGDFTTADKQQAVVAGAYAYTLHQGSVDNLDGDWYLRSQLKDTPTP 1025 +V+ S F+L A+K V G Y Y L N +G W L K P P Sbjct: 527 LVQTPLGSAATFTL------ANKDGKVDIGTYRYRL----AANGNGQWSLVGA-KAPPAP 575 Query: 1026 TPTPQPQFNPGVPLYEGAVQNMQRLNRLPTLQQRVGNSYWNGPSYPAIEQGGAPAGADPA 1085 P PQP P P P Q G A G Sbjct: 576 KPAPQPGPQPPQPPQPQPEA--------PAPQPPAGREL------SAAANAAVNTGGVGL 621 Query: 1086 SSPVA--------------GVVTSDNGIWARIGGDYSKLQSSRSLTNMSQNIRTVIIQSG 1131 +S + + G W R +L +R+ Q + + G Sbjct: 622 ASTLWYAESNALSKRLGELRLNPDAGGAWGRGFAQRQQL-DNRAGRRFDQKVAG--FELG 678 Query: 1132 VDGKFYEADTGKLIGGINALYGSAISRINSPSGDGDATTSAWGLGGTLTWYGESGFYVDG 1191 D A +GG L G GDG T + +GG T+ +SGFY+D Sbjct: 679 ADHAVAVAGGRWHLGG---LAGYTRGDRGFT-GDGGGHTDSVHVGGYATYIADSGFYLDA 734 Query: 1192 QAQINWYNNDYN-SDTAGKGLADDKKATGYAVSIETGQRFNIGERWSVTPQAQLMWSKLS 1250 + + ND+ + + G + + G S+E G+RF + W + PQA+L + Sbjct: 735 TLRASRLENDFKVAGSDGYAVKGKYRTHGVGASLEAGRRFTHADGWFLEPQAELAVFRAG 794 Query: 1251 MDTFNNIWEANVSLNDSDSLIGRAGVALDYRNAWQDDAGQIVHTNIYVIANIYQEFMGNG 1310 + V S++GR G+ + R G+ V Y+ A++ QEF G G Sbjct: 795 GGAYRAANGLRVRDEGGSSVLGRLGLEVGKRIELAG--GRQVQP--YIKASVLQEFDGAG 850 Query: 1311 RVGVADTTFSVKQDVTWGGVGLG 1333 V + T +GLG Sbjct: 851 TVHTNGIAHRTELRGTRAELGLG 873
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 34.2 bits (78), Expect = 6e-04 Identities = 11/29 (37%), Positives = 11/29 (37%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 P PPP P P P P P PP Sbjct: 57 PPQAVQPPPEPVVEPEPEPEPIPEPPKEA 85 Score = 33.0 bits (75), Expect = 0.001 Identities = 11/29 (37%), Positives = 12/29 (41%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 PP P P P P P PP +P V Sbjct: 62 QPPPEPVVEPEPEPEPIPEPPKEAPVVIE 90 Score = 32.7 bits (74), Expect = 0.002 Identities = 10/29 (34%), Positives = 11/29 (37%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 P P P P P PP P P +P Sbjct: 68 VVEPEPEPEPIPEPPKEAPVVIEKPKPKP 96 Score = 32.3 bits (73), Expect = 0.002 Identities = 10/29 (34%), Positives = 10/29 (34%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 PPP P P P P P PP Sbjct: 60 AVQPPPEPVVEPEPEPEPIPEPPKEAPVV 88 Score = 31.9 bits (72), Expect = 0.003 Identities = 18/64 (28%), Positives = 21/64 (32%), Gaps = 7/64 (10%) Query: 200 INPAPPPPPPPPSPCP-----PPPCPPPPPSPPVRPSYTI--QIDAVVDNIPIPTGRGDI 252 P P P P PP P P P P P P P + + V P Sbjct: 71 PEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDVKPVESRPASPFENTAP 130 Query: 253 ARVT 256 AR+T Sbjct: 131 ARLT 134 Score = 31.5 bits (71), Expect = 0.004 Identities = 10/29 (34%), Positives = 11/29 (37%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 P P P P P P P P P +P Sbjct: 64 PPEPVVEPEPEPEPIPEPPKEAPVVIEKP 92 Score = 30.3 bits (68), Expect = 0.009 Identities = 9/29 (31%), Positives = 10/29 (34%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 P P P P P P P P +P Sbjct: 70 EPEPEPEPIPEPPKEAPVVIEKPKPKPKP 98 Score = 29.2 bits (65), Expect = 0.021 Identities = 9/29 (31%), Positives = 10/29 (34%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 P P P P P PP P +P Sbjct: 66 EPVVEPEPEPEPIPEPPKEAPVVIEKPKP 94 Score = 28.4 bits (63), Expect = 0.041 Identities = 8/29 (27%), Positives = 9/29 (31%) Query: 202 PAPPPPPPPPSPCPPPPCPPPPPSPPVRP 230 P P P P P P PP + Sbjct: 63 PPPEPVVEPEPEPEPIPEPPKEAPVVIEK 91
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 57.5 bits (139), Expect = 3e-11 Identities = 75/356 (21%), Positives = 138/356 (38%), Gaps = 21/356 (5%) Query: 55 LGMVGLVQFLPALLLVLVTGAAADRFGRRLIMGLSLILEGIVTAALLAFTLAGLFEPLTV 114 L + L+QF A +L GA +DRFGRR ++ +SL A L Sbjct: 49 LALYALMQFACAPVL----GALSDRFGRRPVLLVSLAG---AAVDYAIMATAPFLWVL-- 99 Query: 115 FAALLIFGVARAFLGPSSASLVVNLVPTEDFANAVSWNSSAWQVATIVGPVAGGLLYGIS 174 + ++ G+ A G + + + ++ ++ A + S+ + + GPV GGL+ G S Sbjct: 100 YIGRIVAGITGA-TGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFS 158 Query: 175 PVAAYSIATLF-LIAGSLLIFSIPKPRQHTLIEER-SISTILAGFRYIWKEKIVLGAISL 232 P A + A + F +P+ + R LA FR+ +V +++ Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAV 218 Query: 233 DLFAVLLGGT-VALLPIYARDILDLGPWGLGLLRSAPGIGAVLTALWLAGHPIRDHAGRA 291 L+G AL I+ D +G+ +A GI L + G P+ G Sbjct: 219 FFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITG-PVAARLGER 277 Query: 292 MFLFVGLFGFFNVIFGLSTLT--WLSILALALAGAADMISVYIRETLMQLWTPDHMRGRV 349 L +G+ L+ T W++ + L + + + + ++ + +G++ Sbjct: 278 RALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGIGMPAL-QAMLSRQVDEERQGQL 336 Query: 350 NAVNMVFVGASNELGEFRAGVMAAAIGAVPAVVIGGIRAIAVAAGWAAMFPQLRKA 405 ++ +G ++ AI A G IA AA + P LR+ Sbjct: 337 QGSLAALTSLTSIVGP----LLFTAIYAASITTWNGWAWIAGAALYLLCLPALRRG 388 Score = 36.3 bits (84), Expect = 2e-04 Identities = 40/196 (20%), Positives = 74/196 (37%), Gaps = 14/196 (7%) Query: 12 FAAFRHSAFKKYWGARFLSAFAVQIVSVSVG--WQIYDLTRDAFNLGMVGL----VQFLP 65 A+FR + A F +Q+V W I+ R ++ +G+ L Sbjct: 200 LASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILH 259 Query: 66 ALLLVLVTGAAADRFGRRLIMGLSLILEGIVTAALLAFTLAGLFEPLTVFAALLIFGVAR 125 +L ++TG A R G R + L +I +G L T + P+ V A G+ Sbjct: 260 SLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLAS--GGIGM 317 Query: 126 AFLGPSSASLVVNLVPTEDFANAVSWNSSAWQVATIVGPVAGGLLYGISPVAAYSIATLF 185 P+ +++ V E ++ + +IVGP+ +Y S + Sbjct: 318 ----PALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS--ITTWNGWAW 371 Query: 186 LIAGSLLIFSIPKPRQ 201 + +L + +P R+ Sbjct: 372 IAGAALYLLCLPALRR 387
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 41.1 bits (96), Expect = 2e-07 Identities = 13/69 (18%), Positives = 25/69 (36%), Gaps = 2/69 (2%) Query: 46 KSRNTRGEAHVAFVIDPSGNVLSARIAVSSGDPAVDQLALEAARRASPVPAPPAAIAKAR 105 ++ G+ V F + P G V + +I + ++ A RR P P + Sbjct: 172 QALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPG--SGIV 229 Query: 106 MPITMPLLF 114 + I + Sbjct: 230 VNILFKING 238
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.0 bits (205), Expect = 2e-20 Identities = 29/124 (23%), Positives = 59/124 (47%), Gaps = 1/124 (0%) Query: 2 RVLLIEDDSAIAQSIELMLKSESFNVYTTDLGEEGIDLGKLYDYDIILLDLNLPDMSGYE 61 +L+ +DD+AI + L ++V T D D+++ D+ +PD + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRTLRLSKVKTPILILSGMAGIEDKVRGLGFGADDYMTKPFHKDELIARI-HAIVRRSK 120 +L ++ ++ P+L++S ++ GA DY+ KPF ELI I A+ + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GHAQ 124 ++ Sbjct: 125 RPSK 128
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 31.4 bits (71), Expect = 0.008 Identities = 8/34 (23%), Positives = 16/34 (47%) Query: 269 VVHLDAANARVIVGPREALETHKVFLRDVNWLGD 302 VVH + +N ++ G ++ + V+ GD Sbjct: 158 VVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGD 191
>PF03309#Bvg accessory factor Length = 271 Score = 27.0 bits (60), Expect = 0.017 Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 44 GALAKAIDLSQSALSQHLAKLRALDLVSTRR 74 GA+A + +S A + A LR ++L R Sbjct: 150 GAIAPGVQVSSDAAAARSAALRRVELTRPRS 180
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 28.7 bits (64), Expect = 0.022 Identities = 18/72 (25%), Positives = 33/72 (45%), Gaps = 9/72 (12%) Query: 60 DPWAMRPELISALSSRMTESGARVLVAEGMMGLFDGAIDGKGSSADLARLLDLPVVLVVD 119 D WA + ++ + T+S A + + G D G+ D+ ++D+PV L V+ Sbjct: 17 DLWA---DALNEQKATTTKSAADAVFQQLGGG------DVSGAMQDIDLIMDIPVKLTVE 67 Query: 120 CARQSHSIAALV 131 R +I L+ Sbjct: 68 LGRTRMTIKELL 79
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.026 Identities = 12/81 (14%), Positives = 32/81 (39%), Gaps = 6/81 (7%) Query: 318 DWLLSIPWGKKSKVKQDLNFAQEVLDAEHFGLGKVKERIVEYLAVQARSTKIKGP----- 372 DW+ + W + ++++ L ++ ++V + ++ P Sbjct: 537 DWVKAQQWDEVPRLEKWLVHVLGKTPDDYKPRRLRYLQLVGKYILMGHVARVMEPGCKFD 596 Query: 373 -ILCLVGPPGVGKTSLARSIA 392 + L G G+GK++L ++ Sbjct: 597 YSVVLEGTGGIGKSTLINTLV 617
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 119 bits (299), Expect = 5e-39 Identities = 50/88 (56%), Positives = 61/88 (69%) Query: 4 NKNELVAAVAEKGGLTKADAGTAVDAVLASVTAALKAGEEVRLPGFGVFSVSHRAASTGR 63 NK +L+A VAE LTK D+ AVDAV ++V++ L GE+V+L GFG F V RAA GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 64 NPSTGKEVAIPARNVPKFSAGKGLKDAV 91 NP TG+E+ I A VP F AGK LKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 36.8 bits (85), Expect = 5e-05 Identities = 41/219 (18%), Positives = 71/219 (32%), Gaps = 37/219 (16%) Query: 11 TVVLVAATGAKAADAVIEQEPAPVVVAPTFTWNGAYLGGQIGYGWGRSTLSDEDTSIRVK 70 T + +A A A + AP N Y G ++G+ T + + Sbjct: 4 TAIAIAVALAGFATVA---QAAPKD-------NTWYTGAKLGWSQYHDTGFINN-NGPTH 52 Query: 71 PDGFLGGLYAGYNFDMGNNFVLGVD--GDITYNDLDASHSDTDPDLDLTTGVDSKLRWSG 128 + G + GY + F +G D G + Y + + + LT + + Sbjct: 53 ENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDL 112 Query: 129 AVRARMGVAMDRWMPYIAGGVAFGNVKNSVSLTDGIESIGVSQSKTMTGWAAGAGVDYAA 188 + R+G + R D ++ T GV+YA Sbjct: 113 DIYTRLGGMVWR--------------------ADTKSNVYGKNHDTGVSPVFAGGVEYAI 152 Query: 189 TDNVIVRLEYRYT----DYGHKDFSVVDGDLSVEARNKF 223 T + RLEY++T D +G LS+ +F Sbjct: 153 TPEIATRLEYQWTNNIGDAHTIGTRPDNGMLSLGVSYRF 191
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.1 bits (62), Expect = 0.014 Identities = 15/51 (29%), Positives = 20/51 (39%), Gaps = 5/51 (9%) Query: 91 RCFL---GETDLNQWMVQEGWAVSYGNYQRDEADARRDKRGIWAGKFERPS 138 RC + G T+ + M WA G Q + K GI K +PS Sbjct: 181 RCNIVSPGSTETD--MQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPS 229
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 97.9 bits (244), Expect = 3e-25 Identities = 68/349 (19%), Positives = 121/349 (34%), Gaps = 44/349 (12%) Query: 6 LITGITGQDGAYLAELLLQKGYAVHGIKRRTSQFNTARIDHLYHDPHEQGVDLTLHHGDL 65 L+TG G G ++++ LL+ G+ V GI ++ + + G H DL Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGF--QFHKIDL 61 Query: 66 TDTSSLVRIMQLVRPDEVYNLGAQSHVAVSFEEPEYTANSDALGALRLLEAIRILGMEKQ 125 D + + + V+ + V S E P A+S+ G L +LE R ++ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ-- 119 Query: 126 TRYYQASTSELYGLVQEIPQKETTPF-YPRSPYAAAKLYAYWITVNYREAYGIYACNGIL 184 AS+S +YGL +++P +P S YAA K + Y YG+ A Sbjct: 120 -HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRF 178 Query: 185 FNHESPLRGETFVTRKITRALA---RIKI---GNQNRLY----------LGNLDSLRDWG 228 F P K T+A+ I + G R + + D + Sbjct: 179 FTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPH-A 237 Query: 229 HARDYVEMQWLMLQQDQPEDFVIATGKQYSVREFVTLAAKDIGIEMRWEGSGEAEKGYDA 288 + VE + I + +++ +GI EA+K Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGI--------EAKKNMLP 289 Query: 289 KTGACIVEVDPRYFRPAEVETLLGDATKAHQKLGWKPKISFETLVSEMI 337 +P +V D ++ +G+ P+ + + V + Sbjct: 290 -------------LQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFV 325
>PF05272#Virulence-associated E family protein Length = 892 Score = 29.7 bits (66), Expect = 0.013 Identities = 16/46 (34%), Positives = 19/46 (41%), Gaps = 9/46 (19%) Query: 51 GISVDIARGERVALIGHNGAGKSTFLKTIAGLY-----PISSGTLK 91 G D + V L G G GKST + T+ GL GT K Sbjct: 592 GCKFDYS----VVLEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGK 633
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 30.1 bits (67), Expect = 5e-04 Identities = 18/50 (36%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Query: 5 AQAQGHEVMPQLIFLLLIIAAAWYGYRSFKREAARVSQRVRQAEKEAQNR 54 AQ E+MP + + +A WY R+ AA Q V +A K+AQ R Sbjct: 348 ENAQKGEIMPNIPQM----SAFWYAVRTAVINAASGRQTVDEALKDAQTR 393
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 43.2 bits (102), Expect = 1e-06 Identities = 62/230 (26%), Positives = 97/230 (42%), Gaps = 45/230 (19%) Query: 14 TLGIDFGTTNTVLSVAAPDGTTAVLSVPKDGVEITGYRSILCFWQDRETGERTAESGPWA 73 L ID GT NT++ V G VL+ P S++ QDR P + Sbjct: 12 DLSIDLGTANTLIYV---KGQGIVLNEP----------SVVAIRQDRA-------GSPKS 51 Query: 74 VDAFVNAPHSTRML-QSFKTFAASKSFKDTPVFGRRFKFEDILQTFLETVAAKLGDRLPP 132 V A V + +ML ++ AA + KD V F E +LQ F++ V + R P Sbjct: 52 VAA-VGHD-AKQMLGRTPGNIAAIRPMKDG-VIADFFVTEKMLQHFIKQVHSNSFMRPSP 108 Query: 133 KGNRVVIGRPVIFAGNAPDEALAMLRYEKAFRAFGFTDIHYVYEPVAAAYFYAQQLTADS 192 RV++ P G E A+ ++ + G ++ + EP+AAA ++ + Sbjct: 109 ---RVLVCVP---VGATQVERRAI---RESAQGAGAREVFLIEEPMAAAIGAGLPVSEAT 159 Query: 193 NVLVADFGGGTSDFSIVRFE--VGKEGLRFTPLSQTGLGIAGDTFDYRII 240 +V D GGGT++ +++ V +R I GD FD II Sbjct: 160 GSMVVDIGGGTTEVAVISLNGVVYSSSVR----------IGGDRFDEAII 199
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 29.0 bits (65), Expect = 0.003 Identities = 18/71 (25%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 21 GVTFMALTAFGLQAARILAPASPKRALARMTVCFSIGQIIGPLVAGFMAQHSGS--FTSA 78 G+T G A I R M+ CF G + GP++ G M S F +A Sbjct: 107 GITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAA 166 Query: 79 SLAAALSLIVA 89 + L+ + Sbjct: 167 AALNGLNFLTG 177
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.3 bits (76), Expect = 9e-04 Identities = 47/208 (22%), Positives = 74/208 (35%), Gaps = 9/208 (4%) Query: 3 AAMGVGRFIYTPILPGMMADIGFST---ADAGFIASANYIGYLVGAVVAGYGWSAGIERM 59 A+G+G + P+LPG++ D+ S A G + + + A V G R Sbjct: 17 DAVGIG--LIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRP 74 Query: 60 VVIAGLAASAVFCFAMALFDGVWILSILRFAAGFASAVTMILCTAIVLSHITRAQRAGLG 119 V++ LA +AV MA +W+L I R AG A T + A + +RA Sbjct: 75 VLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGA-TGAVAGAYIADITDGDERARHF 133 Query: 120 AMHFGGVGSGITLSALLVALIRFSGLGWRADWIGAGLLTLVIMAVVTAFVKEGPVGGNNG 179 G G+ +L L+ G A + A L + + E G Sbjct: 134 GFMSACFGFGMVAGPVLGGLM--GGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRP 191 Query: 180 MREPPLPNSFAFHALAFAYGIFGFGYVI 207 +R N A A + + Sbjct: 192 LRR-EALNPLASFRWARGMTVVAALMAV 218
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 3e-09 Identities = 37/195 (18%), Positives = 73/195 (37%), Gaps = 21/195 (10%) Query: 112 DLIAELDAETEQIAVAKAETALKDAQTTRQRIARLRATNTATEVQAVGAELAVANAQLAL 171 + + EL Q+ + E+ + A+ Q + +L +++ + + +LA Sbjct: 263 EAVNELRVYKSQLE--QIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELA- 319 Query: 172 QDAQLALSRRMVRAPITGIVGILPVNA-GNYVTA-QTSIARIDDRSTVLIDIWVPERFAP 229 + ++RAP++ V L V+ G VT +T + + + T+ + V + Sbjct: 320 -KNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIG 378 Query: 230 QIKVGQPLTAESTAFPGEIYKGRIN------AVDNMLDEAS--------RTLHVRAEVPN 275 I VGQ + AFP Y G + +D + D+ N Sbjct: 379 FINVGQNAIIKVEAFPYTRY-GYLVGKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGN 437 Query: 276 AEDRLRAGMSFSVTI 290 L +GM+ + I Sbjct: 438 KNIPLSSGMAVTAEI 452 Score = 43.3 bits (102), Expect = 1e-06 Identities = 14/91 (15%), Positives = 41/91 (45%) Query: 89 VTPYSSGYMTKLHVRAGDTVKEGDLIAELDAETEQIAVAKAETALKDAQTTRQRIARLRA 148 + P + + ++ V+ G++V++GD++ +L A + K +++L A+ + R L Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 149 TNTATEVQAVGAELAVANAQLALQDAQLALS 179 + ++ + ++ ++ S Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTS 189
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1097 bits (2838), Expect = 0.0 Identities = 451/570 (79%), Positives = 507/570 (88%) Query: 1 MPARISRATYAQMFGPTVGDKVRLADTDLIIEVERDLTTYGEEVKFGGGKVIRDGMGQSQ 60 M R+SRA YA MFGPTVGDKVRLADT+L IEVE+D TT+GEEVKFGGGKVIRDGMGQSQ Sbjct: 1 MSYRMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQ 60 Query: 61 LSRAEGAMDTVITNALILDHSGIYKADIGLLDGRIALIGKAGNPDTQPGISIIIGPGTEI 120 ++R GA+DTVITNALILDH GI KADIGL DGRIA IGKAGNPD QPG++II+GPGTE+ Sbjct: 61 VTREGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEV 120 Query: 121 IAGEGKIVTAGGIDTHVHFISPQQVDEALNAGITCMVGGGTGPAHGTLATTCTPGPWHIA 180 IAGEGKIVTAGG+D+H+HFI PQQ++EAL +G+TCM+GGGTGPAHGTLATTCTPGPWHIA Sbjct: 121 IAGEGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIA 180 Query: 181 RLIQSFDGLPMNIGVFGKGNASLPGALEEMVRAGACGLKLHEDWGCTPAAIDNCLSVADH 240 R+I++ D PMN+ GKGNASLPGAL EMV GA LKLHEDWG TPAAID CLSVAD Sbjct: 181 RMIEAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADE 240 Query: 241 FDVQVAIHTDTLNEGGFVEDTLNAFKGRTIHSFHTEGAGGGHAPDIIRVCQYPNVLPAST 300 +DVQV IHTDTLNE GFVEDT+ A KGRTIH++HTEGAGGGHAPDIIR+C PNV+P+ST Sbjct: 241 YDVQVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSST 300 Query: 301 NPTRPYTVNTIAEHLDMLMVCHHLSPAIPEDIAFAESRIRKETIAAEDILHDMGAFSIIS 360 NPTRPYTVNT+AEHLDMLMVCHHLSP IPEDIAFAESRIRKETIAAEDILHD+GAFSIIS Sbjct: 301 NPTRPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIIS 360 Query: 361 SDSQAMGRVGEMIIRCWQTADKMKKQRGSLPDDRPGNDNYRARRYIAKYTINPAIAHGMA 420 SDSQAMGRVGE+ IR WQTADKMK+QRG L ++ NDN+R +RYIAKYTINPAIAHG++ Sbjct: 361 SDSQAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLS 420 Query: 421 HEIGSVEVGKRADLVLWNSAFFGVKPDMVLLGGWIATAPMGDANGSIPTPQPMHTRPMFG 480 HEIGS+EVGKRADLVLWN AFFGVKPDMVLLGG IA APMGD N SIPTPQP+H RPMFG Sbjct: 421 HEIGSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFG 480 Query: 481 SFGKALTNTSITFVSQAAMDEGLREKIGVDKQLVAVVNTRGGIGKHSMILNNAMPQMEVD 540 ++G++ TN+S+TFVSQA++D GL ++GV K+LVAV NTRGGIGK SMI N+ P +EVD Sbjct: 481 AYGRSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVD 540 Query: 541 PETYEVRADGELLTCEPVDVVPMAQRYFLF 570 PETYEVRADGELLTCEP V+PMAQRYFLF Sbjct: 541 PETYEVRADGELLTCEPATVLPMAQRYFLF 570
>TRNSINTIMINR#Translocated intimin receptor (Tir) signature. Length = 549 Score = 30.1 bits (67), Expect = 0.009 Identities = 30/93 (32%), Positives = 50/93 (53%), Gaps = 11/93 (11%) Query: 14 AQQAISSAKSLSTQKS-KMSELERATRD--GAAI--GKKRADIAKKIADKAKQLSSYQAK 68 A A S+ K TQ++ K E ++ D G AI G+ + DI ++IA +AK+ + A+ Sbjct: 275 ANAAESATKDQLTQEAFKNPENQKVNIDANGNAIPSGELKDDIVEQIAQQAKE-AGEVAR 333 Query: 69 QFKADEQAVKKVAQEQKRLSDERTKHEAFIKQS 101 Q QAV+ AQ Q+R D+ + + ++ S Sbjct: 334 Q-----QAVESNAQAQQRYEDQHARRQEELQLS 361
>PERTACTIN#Pertactin signature. Length = 922 Score = 30.1 bits (67), Expect = 0.002 Identities = 17/53 (32%), Positives = 18/53 (33%) Query: 15 FVLAKVFGNDKPSPVPPSIPVAPQAATQPAEQAPQPLGFIQATSPRQTDQPPA 67 V AK KP+P P P Q PQP Q QPPA Sbjct: 562 LVGAKAPPAPKPAPQPGPQPGPQPPQPPQPPQPPQPPQPPQRQPEAPAPQPPA 614
>FLAGELLIN#Flagellin signature. Length = 507 Score = 24.2 bits (52), Expect = 0.045 Identities = 7/23 (30%), Positives = 15/23 (65%) Query: 4 DRLSIAAEIERLIDMLDQMDDDT 26 D SI EI++ ++ +D++ + T Sbjct: 107 DLKSIQDEIQQRLEEIDRVSNQT 129
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 86.7 bits (214), Expect = 1e-20 Identities = 51/151 (33%), Positives = 78/151 (51%), Gaps = 9/151 (5%) Query: 71 LSGDKQKFIDTLLPAAIEHGQRIGVDPRIIVAQAAQETGWG-------RSAPGNNFFGIK 123 L GD + F+ L A Q+ GV +I+AQAA E+GWG P N FG+K Sbjct: 145 LPGDSKAFLAQLSLPAQLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVK 204 Query: 124 SHG--QGGGQNLTTHEVINGQRVKINDSFRTFASPQDSVAGYADFIASNKRYRPMREAQG 181 + G +G +TT E NG+ K+ FR ++S ++++ Y + N RY + A Sbjct: 205 ASGNWKGPVTEITTTEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAAS 264 Query: 182 LDAQLQALGASGYATDPNYARSVGAIARSIN 212 + QAL +GYATDP+YAR + + + + Sbjct: 265 AEQGAQALQDAGYATDPHYARKLTNMIQQMK 295
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.1 bits (83), Expect = 3e-05 Identities = 21/101 (20%), Positives = 32/101 (31%), Gaps = 7/101 (6%) Query: 59 LEQVD--GNAIFGAFHGEELLGIAGHHRHERRTERHRGTLASVYVEPQARGLKLGEALVQ 116 + V+ G A F + +G R + + V R +G AL+ Sbjct: 57 VSYVEEEGKAAFLYYLENNCIG----RIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLH 112 Query: 117 KVIDHA-ARHVVVLDARVVATNGAAKRIYYALGFKTCGVER 156 K I+ A H L N +A Y F V+ Sbjct: 113 KAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGAVDT 153
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 43.3 bits (102), Expect = 1e-08 Identities = 28/75 (37%), Positives = 38/75 (50%), Gaps = 1/75 (1%) Query: 78 RKEARAGAANAAALSGLRYDNRPGKVSIATGVGGFKGSTALAAGIGYTSKNENARYNVSV 137 KE + G AN +ALS L N GK S++ VGG++ TALA G+G + V Sbjct: 2 SKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRI-TDRFTAKAGV 60 Query: 138 AYNEAGTSWNAGASF 152 A+N + GAS Sbjct: 61 AFNTYNGGMSYGASV 75
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 39.0 bits (91), Expect = 2e-05 Identities = 25/124 (20%), Positives = 45/124 (36%), Gaps = 11/124 (8%) Query: 134 VPIINENDTVATTEIRYGDNDRLAARVATMMGADLLILLSDIDGLYTAPPHKNPDAQFLP 193 VP+I E+ + E D D ++A + AD+ ++L+D++G + Q+L Sbjct: 197 VPVILEDGEIKGVEAVI-DKDLAGEKLAEEVNADIFMILTDVNGAALY--YGTEKEQWL- 252 Query: 194 FVETITPQIEAMAGAAASELSRGGMKTKLDAG-KIANAAGTAMIITSGTRFGPLSAIDRG 252 + + E G M K+ A + G II + G Sbjct: 253 --REVKVE-ELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAIIAHLEK---AVEALEG 306 Query: 253 ERAT 256 + T Sbjct: 307 KTGT 310
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 27.5 bits (61), Expect = 0.031 Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 34 GLFGGSFNPPHGGHALVAEIAIRRLKLDQLWWMVTPGNPLKDSRELAPLSERLRLSEEVA 93 ++ GSF+P GH + E R DQ++ V NP K + + + ERL + Sbjct: 3 AIYPGSFDPITFGHLDIIERGCR--LFDQVYVAVL-RNPNK--QPMFSVQERLEQIAKAI 57 Query: 94 ED-PRIKVTALE 104 P +V + E Sbjct: 58 AHLPNAQVDSFE 69
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 123 bits (311), Expect = 7e-37 Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 11/126 (8%) Query: 51 QDFTVNVGDRIFFDLDSSLIRADAQQTLSKQAQWLQRY--PQYSITIEGHADERGTREYN 108 Q + + F+ + + ++ + Q L + L S+ + G+ D G+ YN Sbjct: 211 QTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYN 270 Query: 109 LALGQRRAAATRDFLASRGVPTNRMRTISYGNERPVA--VCDAD-------TCWSQNRRA 159 L +RRA + D+L S+G+P +++ G PV CD C + +RR Sbjct: 271 QGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRV 330 Query: 160 VTVLNG 165 + G Sbjct: 331 EIEVKG 336
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 30.7 bits (69), Expect = 0.002 Identities = 24/113 (21%), Positives = 35/113 (30%), Gaps = 11/113 (9%) Query: 66 TDDNPNSLYQAAYQYLMSGDYKAAEAGFREHVKRYPADPMTAEARFW--LGESLYGQGRY 123 + D LY A+ SG Y+ A F+ D RF+ LG G+Y Sbjct: 32 SSDTLEQLYSLAFNQYQSGKYEDAHKVFQALCVLDHYDS-----RFFLGLGACRQAMGQY 86 Query: 124 PEAATLF---IDTQRDYPD-SKRAPENMFKLGMALEKMDNHDVACATFAQIPQ 172 A + P A E + + G E +A A + Sbjct: 87 DLAIHSYSYGAIMDIKEPRFPFHAAECLLQKGELAEAESGLFLAQELIADKTE 139
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.7 bits (77), Expect = 0.003 Identities = 23/82 (28%), Positives = 32/82 (39%), Gaps = 18/82 (21%) Query: 200 VLLVGPPGTGKTLLARSV---AGEANVPFFT-----ISGSDFVEMFVGV------GASRV 245 +++ G GTGK L+AR++ N PF I G GA Sbjct: 163 LMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTR 222 Query: 246 RD-MFEQAKKNAPCIIFIDEID 266 FEQA+ +F+DEI Sbjct: 223 STGRFEQAEGGT---LFLDEIG 241
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 28.7 bits (64), Expect = 0.027 Identities = 30/181 (16%), Positives = 52/181 (28%), Gaps = 32/181 (17%) Query: 90 SFLIGGGAGYQVTDYFRTDLTLDYMTRSRFSGHVSGPDCNGDTGCASDERSHYSALSILA 149 G GYQV Y ++ D++ R + G S E Y A + Sbjct: 55 QLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKG--------------SVENGAYKAQGVQL 100 Query: 150 NAYVDLGNLGGVTPYVGAGIGGTRVNWSDLVDITSGFSQEGAANWRFTYALMAGASVDLT 209 A + + Y G R + V + + + G +T Sbjct: 101 TAKLGYPITDDLDIYTRLGGMVWRADTKSNVYGKN-------HDTGVSPVFAGGVEYAIT 153 Query: 210 HNLKLDAGYRYRHVNGGKMFEGNQWTDAG-YDKGLNIHDIRVGLRYMFGGSDNAAYASQA 268 + Y++ N DA + + +G+ Y FG + A + A Sbjct: 154 PEIATRLEYQWT----------NNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPA 203 Query: 269 A 269 Sbjct: 204 P 204
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 125 bits (314), Expect = 1e-36 Identities = 56/188 (29%), Positives = 90/188 (47%), Gaps = 5/188 (2%) Query: 6 KVVIVTGGASGIGEATARAFIREGAKVVIADFSDHGQQL---ADELAGAHEQALFIKTDV 62 K+ +TG A GIGEA AR +GA + D++ + + + H +A DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF--PADV 66 Query: 63 ADTRAVQALIARTVENYGRLDIMFANAGIAADAPIDELDEAAWQKTIDINLTGVYLCDKY 122 D+ A+ + AR G +DI+ AG+ I L + W+ T +N TGV+ + Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 123 AIDQMRSQGGGVIVNCGSIHSHVGKSGVTAYAAAKGGVKLLTQTLAIDYGPQNIRVNAVC 182 M + G IV GS + V ++ + AYA++K + T+ L ++ NIR N V Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGYIDTPL 190 PG +T + Sbjct: 187 PGSTETDM 194
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 609 bits (1573), Expect = 0.0 Identities = 376/481 (78%), Positives = 430/481 (89%), Gaps = 2/481 (0%) Query: 45 GTVLVADDDAAIRTVLNQALSRAGYDVRVTSNAASLWRWVAAGDGDLVISDVMMPDENAF 104 T+LVADDDAAIRTVLNQALSRAGYDVR+TSNAA+LWRW+AAGDGDLV++DV+MPDENAF Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 105 DLLPRIKKIRPDLPVVVMSAQNTFMTAIRASEAGAYEYLPKPFDLTELINIVGRALSEPR 164 DLLPRIKK RPDLPV+VMSAQNTFMTAI+ASE GAY+YLPKPFDLTELI I+GRAL+EP+ Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 165 QKPAVALPDEQGENMPLVGRSPAMQEIYRLLARMMQTDLTVMVTGESGTGKELVARALHE 224 ++P+ D Q + MPLVGRS AMQEIYR+LAR+MQTDLT+M+TGESGTGKELVARALH+ Sbjct: 124 RRPSKLEDDSQ-DGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 225 YGRRRKGPFVAINMAAIPRDLIESELFGHEKGAFTGAQNRSSGRFEQANGGTLFLDEIGD 284 YG+RR GPFVAINMAAIPRDLIESELFGHEKGAFTGAQ RS+GRFEQA GGTLFLDEIGD Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGD 242 Query: 285 MPMEAQTRLLRVLQQGEYMTVGGRTPIKTDVRIVAATNRDLRQIIAQGLFREDLYYRLNV 344 MPM+AQTRLLRVLQQGEY TVGGRTPI++DVRIVAATN+DL+Q I QGLFREDLYYRLNV Sbjct: 243 MPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNV 302 Query: 345 VPLRLPPLRERSEDVPDLVRHFFKRAAEEGVPEKRITNAGLEMMRRYPWPGNVRELENLV 404 VPLRLPPLR+R+ED+PDLVRHF ++A +EG+ KR LE+M+ +PWPGNVRELENLV Sbjct: 303 VPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGNVRELENLV 362 Query: 405 RRLAALYPQEEIAPEIIETELKAELAKPDVVAAAGGEMENISISQAVEQNMQRYFASFGS 464 RRL ALYPQ+ I EIIE EL++E+ + A ++SISQAVE+NM++YFASFG Sbjct: 363 RRLTALYPQDVITREIIENELRSEIPDSP-IEKAAARSGSLSISQAVEENMRQYFASFGD 421 Query: 465 DLPPPGLYQRVLAEVEYPLILACLTATRGNQIKAADLLGLNRNTLRKKIRELGVNIYRGA 524 LPP GLY RVLAE+EYPLILA LTATRGNQIKAADLLGLNRNTLRKKIRELGV++YR + Sbjct: 422 ALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVSVYRSS 481 Query: 525 K 525 + Sbjct: 482 R 482
>PF06580#Sensor histidine kinase Length = 349 Score = 40.2 bits (94), Expect = 2e-05 Identities = 11/60 (18%), Positives = 23/60 (38%), Gaps = 12/60 (20%) Query: 638 KEERGEGHIRIHAYRADGQLVVDVIDNGKGLPGDDRQKLLEPYMTTREKGTGLGLAIVRK 697 + G I + + +G + ++V + G + ++ TG GL VR+ Sbjct: 273 AQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE------------STGTGLQNVRE 320
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 421 bits (1083), Expect = e-146 Identities = 168/482 (34%), Positives = 258/482 (53%), Gaps = 39/482 (8%) Query: 2 AADILVVDDEVDIRDLVAGILSDEGHETRTAFDADSALAAINDRAPRLVFLDIWLQGSRL 61 A ILV DD+ IR ++ LS G++ R +A + I LV D+ + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPD--E 60 Query: 62 DGLALLDEIKKQHPELPVVMISGHGNIETAVSAIRRGAYDFIEKPFKADRLILVAERALE 121 + LL IKK P+LPV+++S TA+ A +GAYD++ KPF LI + RAL Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 122 TSKLKREVSDLRKRTGDQLELVGTSLAMNQLRQTIERVAPTNSRIMITGPSGAGKELVAR 181 K + + + G LVG S AM ++ + + R+ T+ +MITG SG GKELVAR Sbjct: 121 EPKRRPSKLEDDSQDGM--PLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVAR 178 Query: 182 AIHAQSSRANGPFVTVNAATITPERMEIELFGTE----MDGGERKVGALEEAHGGILYLD 237 A+H R NGPFV +N A I + +E ELFG E R G E+A GG L+LD Sbjct: 179 ALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLD 238 Query: 238 EVADMPRETQNKILRVLVDQQFERVGGTKRVKVDVRIISSTAQNLEGMIAEGTFREDLFH 297 E+ DMP + Q ++LRVL ++ VGG ++ DVRI+++T ++L+ I +G FREDL++ Sbjct: 239 EIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYY 298 Query: 298 RLSVVPVQVPALAARREDIPSLVEFFMKQIAEQAGIKPRKIGPDAMAVLQAHSWPGNLRQ 357 RL+VVP+++P L R EDIP LV F++Q AE+ G+ ++ +A+ +++AH WPGN+R+ Sbjct: 299 RLNVVPLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVRE 357 Query: 358 LRNNVERLMILTRGDDPDELVTADLLPAEIGDTLPRAPTES------------------- 398 L N V RL L P +++T +++ E+ +P +P E Sbjct: 358 LENLVRRLTALY----PQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMR 413 Query: 399 -------DQHIMALPLREARERFEKEYLIAQINRFGGNISRTAEFVGMERSALHRKLKSL 451 D + E ++A + GN + A+ +G+ R+ L +K++ L Sbjct: 414 QYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIREL 473 Query: 452 GV 453 GV Sbjct: 474 GV 475
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.0 bits (65), Expect = 0.037 Identities = 11/31 (35%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Query: 1 MRVIVCG-AGQVGYGIAERLAAEENDVSVID 30 M+ +V G AG +G+ +++RL + V ID Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGID 31
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 32.2 bits (73), Expect = 0.002 Identities = 11/33 (33%), Positives = 18/33 (54%) Query: 51 LTVVQFSDIFRIMLIKYQQGVWLDTDVYLLKQF 83 + FSDI R+ L+ G+W+D VY+ + Sbjct: 129 MLDAWFSDILRLFLLCKYGGLWIDATVYMFDKV 161
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 175 bits (444), Expect = 7e-59 Identities = 65/160 (40%), Positives = 100/160 (62%), Gaps = 5/160 (3%) Query: 3 IAIYAGSFDPVTNGHIDVLKGALRLADQVIVAIGMHPGKKPLFSFDERVALIEASAKAVL 62 AIY GSFDP+T GH+D+++ RL DQV VA+ +P K+P+FS ER+ I + Sbjct: 2 NAIYPGSFDPITFGHLDIIERGCRLFDQVYVAVLRNPNKQPMFSVQERLEQIAKAIA--- 58 Query: 63 HKDAARVSVIAFDGLVIDAARKHGAQLMVRGLRDGTDLDYEMQMAGMNGTMAPELQTVFL 122 V +F+GL ++ AR+ A ++RGLR +D + E+QMA N T+A +L+TVFL Sbjct: 59 --HLPNAQVDSFEGLTVNYARQRQAGAILRGLRVLSDFELELQMANTNKTLASDLETVFL 116 Query: 123 PADPAVRTITATLVRQIASMGGDIKPFVPVAVAAALNTKF 162 ++++LV+++A GG+++ FVP VAAAL +F Sbjct: 117 TTSTEYSFLSSSLVKEVARFGGNVEHFVPSHVAAALYDQF 156
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 2e-12 Identities = 25/155 (16%), Positives = 52/155 (33%), Gaps = 5/155 (3%) Query: 3 PTKRENSREKILRAATELAQEVGPAHISLDAVAARAGLSKGGLLYSFPTKAKLLEAMVEK 62 + + +R+ IL A L + G + SL +A AG+++G + + F K+ L + E Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 63 YMQEHEQAMAVQETLQSGERNRVARAFLDVYRIQADKEPPACGVLAALAENPDFMVPVRH 122 + + G+ V R L E ++ + F Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEII-----FHKCEFV 120 Query: 123 YHRALLDRMVSDAVDPDTALIAYLAIAGMQSGKLL 157 A++ + + I +++ L Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLP 155
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 7e-05 Identities = 17/89 (19%), Positives = 37/89 (41%), Gaps = 1/89 (1%) Query: 60 GVLQKINFKANQDVKQGDILLQMEDSIQRADLAAAEAEAVLAQQNLKRADTLRT-RGVGA 118 ++++I K + V++GD+LL++ AD ++ + A+ R L + Sbjct: 105 SIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNK 164 Query: 119 VSNVDTTAMPANAAVALVKKMRATLAQKS 147 + + P V+ + +R T K Sbjct: 165 LPELKLPDEPYFQNVSEEEVLRLTSLIKE 193
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 805 bits (2080), Expect = 0.0 Identities = 317/1032 (30%), Positives = 521/1032 (50%), Gaps = 30/1032 (2%) Query: 4 SDIFIRRPVLATVVSLMIVLLGLQGIAQLSVREYPKVDETVITVTTAYAGASADLIQGFI 63 ++ FIRRP+ A V+++++++ G I QL V +YP + ++V+ Y GA A +Q + Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TAPIAEAVATTENIDYVTSSS-RPSSSTVTVQMKLGADPDAALTEVIAKVNQVRGNLPDE 122 T I + + +N+ Y++S+S S T+T+ + G DPD A +V K+ LP E Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 SDDPVIVKGTGQSFATMYLA--AQNPNMTSEQITEYLKRVIQPRMSTIQGVAKAEILGGQ 180 I S M + NP T + I++Y+ ++ +S + GV ++ G Q Sbjct: 122 VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQ 181 Query: 181 VYSMRVWLDPIQLAARQITAPEVLSAIKASN------FLSAPGKTKNEYVATSITLKSTL 234 Y+MR+WLD L ++T +V++ +K N L + + SI ++ Sbjct: 182 -YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 235 QTPEAFGAMPIKALGD-EVVRLRDVAKVELAAESTDTIVSFNGSAGTFLGVYPTPAANPI 293 + PE FG + ++ D VVRL+DVA+VEL E+ + I NG LG+ AN + Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 294 DMAAAVRKELPSIQASLPEGMSLVLVYDATEQISSSINEVFTTIGEAVAIVILVIIVFLG 353 D A A++ +L +Q P+GM ++ YD T + SI+EV T+ EA+ +V LV+ +FL Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 354 SFRSVLIPIVTIPISLIGVCFFLYVLGFSINLLSLLAMVLAIGLVVDDAIVVLENIHRHI 413 + R+ LIP + +P+ L+G L G+SIN L++ MVLAIGL+VDDAIVV+EN+ R + Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 414 -EEGLHPIDAAFKGMKEITGSIVAMTITLAAVFTPLGFTGGLTGSLFREFAFTLAGAVII 472 E+ L P +A K M +I G++V + + L+AVF P+ F GG TG+++R+F+ T+ A+ + Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 473 SGIAALTISPMMCSRMLK------HGDQTRFQKFIDRTFSRFEKWYHARVSNSLNYRWIT 526 S + AL ++P +C+ +LK H ++ F + + TF Y V L Sbjct: 481 SVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRY 540 Query: 527 LAIVLCLMGLTGFLFMNTSSELAPEEDSGALFSMFQAPQYATSAYTNLYAEQI--DALTK 584 L I ++ LF+ S PEED G +M Q P AT T +Q+ L Sbjct: 541 LLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKN 600 Query: 585 DLPEQKTRFQIVGMD---GGTTSGIALWVLKDWNERDRSQKQIQQDLTARISKVAGVQ-A 640 + ++ F + G +G+A LK W ER+ + + + ++ ++ Sbjct: 601 EKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDG 660 Query: 641 FIFAPPSLP----GTGGGLPISIALQSTGPADQVFALAEEIKAEA-QASGQFIIVQNSLS 695 F+ GT G + Q+ D + ++ A Q + V+ + Sbjct: 661 FVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGL 720 Query: 696 FNAPQTTITIDRDRAATLGVQVSDIGSTLGLLTGGASIAKFDRDSNSYDIITQVPDSYRA 755 + Q + +D+++A LGV +SDI T+ GG + F + Q +R Sbjct: 721 EDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRM 780 Query: 756 NPEMLGNFYVRSVSGSMVPLSSVIQINENAAPAAIEQFNQLNSATISALPLPGVTTGQGL 815 PE + YVRS +G MVP S+ + +E++N L S I PG ++G Sbjct: 781 LPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD-A 839 Query: 816 QTLVDIARSKMPEGFFLDYSCQSRLEVEQGNTILIAFGFAVFVIYLVLAAQFESFRDPFI 875 L++ SK+P G D++ S E GN + V++L LAA +ES+ P Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 876 IMMSVPLSIFGAIVPLNIGLGTLNIYTQVGLITLVGLITKHGILMVEFANQQRRLHGLSR 935 +M+ VPL I G ++ + ++Y VGL+T +GL K+ IL+VEFA G Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 936 RDAIVVAAETRLRPILMTTAAMALGVVPLIIATGAGAAARYSMGLVIFTGITIGTIFTLF 995 +A ++A RLRPILMT+ A LGV+PL I+ GAG+ A+ ++G+ + G+ T+ +F Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 996 VVPMFYTFIAKK 1007 VP+F+ I + Sbjct: 1020 FVPVFFVVIRRC 1031
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 42.2 bits (99), Expect = 3e-06 Identities = 57/383 (14%), Positives = 130/383 (33%), Gaps = 56/383 (14%) Query: 39 STTTIGWMGTSYSLAFTIGCIFIPHLVRRVGHVRVFSALLTLLSMALLFHALVVNPAAWM 98 + W+ T++ L F+IG L ++G R+ + + + + + + + Sbjct: 47 PPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLL 106 Query: 99 IF----RGITGFSLAGSYMIIES-WLNERVTNESRGMIFSI------------------- 134 I +G + M++ + ++ + ++ G+I SI Sbjct: 107 IMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI 166 Query: 135 -------YMIITMVGLLLGQYILPFGNAATQTLFIICAIIYASALLPTALSSAQSPNPLT 187 +IT++ + +L I I+ + ++ L + Sbjct: 167 HWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFL 226 Query: 188 QVSLDLKGLYRRSPAAV--------------------VGSFIAGIVAGTWNFLAAIYGEM 227 VS+ ++ + V G I G VAG + + + ++ Sbjct: 227 IVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDV 286 Query: 228 NGLSTFGIAT-MLASAMIGGAIFQYPLGRASDFVDRRYMMILAGAIGFTLSFIMVLFHP- 285 + LST I + ++ + IF Y G D Y++ + ++SF+ F Sbjct: 287 HQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTF-LSVSFLTASFLLE 345 Query: 286 -TSPYTLYAMMFLFGSVVFPIYSLNVAHANDYADASEFVKISGGLLIVYGVGSVLGPAIS 344 TS + ++F+ G + F ++ ++ +S + + G AI Sbjct: 346 TTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSF-LSEGTGIAIV 404 Query: 345 GPLMDVIGANGFFVTMAIAYCIY 367 G L+ + + + M + Y Sbjct: 405 GGLLSIPLLDQRLLPMEVDQSTY 427
>PF05844#YopD protein Length = 295 Score = 30.4 bits (68), Expect = 0.026 Identities = 24/104 (23%), Positives = 32/104 (30%), Gaps = 9/104 (8%) Query: 657 IAAIASGYADGFAGLYDTLKQEGAFSPDAAPAGKRALRSALLDYLSVQEKSPERAER--- 713 + A+AS LK A S + R+ L+D +R Sbjct: 129 VGALASAVVGSLG----ALKNGKAISQEKTLQKNIDGRNELIDAKMQALGKTSDEDRKIV 184 Query: 714 -QFVEADNMTDRATALAVLVHRFGDSGEARQALATFEQTFGQDA 756 + AD D AL F A Q T Q+F Q A Sbjct: 185 GKVWAADQAQDSV-ALRAAGRAFESRNGALQVANTVIQSFVQMA 227
>PF06580#Sensor histidine kinase Length = 349 Score = 42.9 bits (101), Expect = 4e-06 Identities = 36/194 (18%), Positives = 76/194 (39%), Gaps = 41/194 (21%) Query: 595 FLLNVINDILDMSKIEAGH-------------FSLDREEIDLCPL------INETVRIIS 635 F+ N +N+I + + +SL L ++ +++ S Sbjct: 174 FMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLAS 233 Query: 636 LQAEEKNIAVETRIEDAMELYADRRAIKQVLI-NLLSNAVKFTSYGGRITVRARKTGAAL 694 +Q E++ + E +I A+ + Q L+ N + + + GG+I ++ K + Sbjct: 234 IQFEDR-LQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTV 292 Query: 695 FMTIQDTGVGIPKSALRKIGQPFEQVENQFTKTHTGSGLGLA-ISRSLAELHGGWLRIRS 753 + +++TG K+ T +G GL + L L+G +I+ Sbjct: 293 TLEVENTGSLALKN------------------TKESTGTGLQNVRERLQMLYGTEAQIKL 334 Query: 754 TERVGTVVSVC-IP 766 +E+ G V ++ IP Sbjct: 335 SEKQGKVNAMVLIP 348
>PF06580#Sensor histidine kinase Length = 349 Score = 35.2 bits (81), Expect = 4e-04 Identities = 20/102 (19%), Positives = 38/102 (37%), Gaps = 20/102 (19%) Query: 363 LVDNAIKYA-GGEGRTATVTLLMEKDAQWVRIVVADNGPGIPADKRDHATERFVRLEESR 421 LV+N IK+ + + L KD V + V + G L Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGS----------------LALKN 306 Query: 422 TQPGSGLGLSLAKSVMKLHGG---ALRLEDNGPGLRAVLEFP 460 T+ +G GL + +++ G ++L + + A++ P Sbjct: 307 TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.7 bits (212), Expect = 2e-21 Identities = 34/128 (26%), Positives = 59/128 (46%), Gaps = 4/128 (3%) Query: 2 KILVIEDDREAARYLEKAFAEAGHSADIAGDGETGYALAENGNYDVLVVDRMLPKRDGLS 61 ILV +DD L +A + AG+ I + T + G+ D++V D ++P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VVAGLRAKGMETPVLILSALGEVDDRVTGLRAGGDDYLTKPYAFSELLARVE----VLQR 117 ++ ++ + PVL++SA + G DYL KP+ +EL+ + +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 118 RSSPREAD 125 R S E D Sbjct: 125 RPSKLEDD 132
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 62.7 bits (152), Expect = 9e-13 Identities = 32/164 (19%), Positives = 53/164 (32%), Gaps = 24/164 (14%) Query: 129 HERPVAQGSGFVISEDGYVVTNNHVVS----DGDAYTVVLD--------DGTELDAKLIG 176 SG V+ ++TN HVV D A +G ++ Sbjct: 97 APTGTFIASGVVVG-KDTLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITK 155 Query: 177 ADPRTDLAVLKINA------PKRKFVYVAFGDDNKVRVGDWVVAVGNPFGLGGTVTSGIV 230 DLA++K + ++ + +V + G P Sbjct: 156 YSGEGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPVATMW--- 212 Query: 231 SARGRDIGAGPYDDFIQIDAAVNKGNSGGPAFDLSGEVIGINTA 274 ++G+ +Q D + GNSG P F+ EVIGI+ Sbjct: 213 ESKGKITYLKGE--AMQYDLSTTGGNSGSPVFNEKNEVIGIHWG 254
>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD chaperone signature. Length = 168 Score = 34.9 bits (80), Expect = 2e-04 Identities = 20/116 (17%), Positives = 38/116 (32%), Gaps = 4/116 (3%) Query: 169 GRASDAVSAYHTSIRIAGENLARILGLGEALTAASGGTVTAEAEKLFKKAAELSPDDIRP 228 G+ DA + + + LGLG A A + A + + R Sbjct: 50 GKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMG---QYDLAIHSYSYGAIMDIKEPRF 106 Query: 229 QYYLAQGEMQDGHPDRAADRLQAFLDKAPADAPWRGQLEKTIAILRDPASAKQAEA 284 ++ A+ +Q G A L + AD +L ++ + + K+ Sbjct: 107 PFHAAECLLQKGELAEAESGLFLAQELI-ADKTEFKELSTRVSSMLEAIKLKKEME 161
>PF06580#Sensor histidine kinase Length = 349 Score = 30.2 bits (68), Expect = 0.016 Identities = 21/101 (20%), Positives = 37/101 (36%), Gaps = 21/101 (20%) Query: 338 LLENAGKWG----RKCITIRLAAVAGEQRQFEIVIEDDGPGLEADKIEAALKRGSRVDET 393 L+EN K G + I L + + +E+ G + T Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTK-DNGTVTLEVENTGSL--------------ALKNT 307 Query: 394 KPGTGLGLAIVQDTVRE-YGGSLHLG-KDALGGLAVRVVLP 432 K TG GL V++ ++ YG + + G + V++P Sbjct: 308 KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.9 bits (210), Expect = 3e-21 Identities = 31/123 (25%), Positives = 61/123 (49%), Gaps = 1/123 (0%) Query: 2 RILIVEDDKDLNRQLSEAMIAAGYVVDSAYDGEEGHYLGDTEPYDAVVLDIGLPQMDGIS 61 IL+ +DD + L++A+ AGY V + D VV D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VVERWRRSGRTIPVLMLTARDRWSDKVAGIDAGADDYVAKPFHIEEVLARL-RALIRRAA 120 ++ R +++ +PVL+++A++ + + + GA DY+ KPF + E++ + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GHA 123 + Sbjct: 125 RPS 127
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 137 bits (346), Expect = 9e-45 Identities = 66/137 (48%), Positives = 95/137 (69%), Gaps = 7/137 (5%) Query: 7 MLKEFQEFALKGNMVDLAIGVIIGGAFGGLVNSIVNDIIMPIIGLITGGIDFSNMFIQLA 66 ++KEF+EFA++GN+VDLA+GVIIG AFG +V+S+V DIIMP +GL+ GGIDF + L Sbjct: 3 IIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLIGGIDFKQFAVTLR 62 Query: 67 GDPKTTLAAAREAGATIAYGNFITLLINFLIIAWVLFLVVKLMNRLKKREEAKPAPAAPS 126 A + YG FI + +FLI+A+ +F+ +KL+N+L +++E A AP+ Sbjct: 63 ------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPAAAPAPT 116 Query: 127 -EEVLLTEIRDILAKQQ 142 EEVLLTEIRD+L +Q Sbjct: 117 KEEVLLTEIRDLLKEQN 133
>PF06580#Sensor histidine kinase Length = 349 Score = 39.1 bits (91), Expect = 8e-05 Identities = 27/108 (25%), Positives = 38/108 (35%), Gaps = 26/108 (24%) Query: 915 LIQNLVSNSIKY-----SRKGGILLGVRRRGNFVDLQVLDTGIGIAPQKLKLVFREFTRL 969 L+Q LV N IK+ + G ILL + V L+V +TG Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------ 306 Query: 970 NEGMREAEGLGLGLSIVDRIARVL---SLPLSLASTPGKGTVFSLRIP 1014 E G GL V ++L + L+ GK + IP Sbjct: 307 -----TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM-VLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 66.4 bits (162), Expect = 5e-15 Identities = 33/117 (28%), Positives = 55/117 (47%), Gaps = 3/117 (2%) Query: 4 IIADDHPLFRGALRQVLSGQSENVEIIEAGDFDTVRKLVGEKDDTDLLLLDLTMPGGTGL 63 ++ADD R L Q LS +V I + T+ + + D DL++ D+ MP Sbjct: 7 LVADDDAAIRTVLNQALSRAGYDVRI--TSNAATLWRWI-AAGDGDLVVTDVVMPDENAF 63 Query: 64 SGLVALKALQPALPIIIVSATDDPATIHHALELGASGFISKSASMETIGEAVGAVLA 120 L +K +P LP++++SA + T A E GA ++ K + + +G LA Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.6 bits (69), Expect = 0.010 Identities = 9/35 (25%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 276 VLARMRERVGPDMPLIGVGGIDSAETALAKIKAGA 310 +L R+++ PD+P++ + ++ TA+ + GA Sbjct: 65 LLPRIKKA-RPDLPVLVMSAQNTFMTAIKASEKGA 98
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 34/193 (17%), Positives = 58/193 (30%), Gaps = 38/193 (19%) Query: 218 MQKQAERMSRLIDDLLSLSRLEMRAHLAVNESVDVAATLAHVADTLTPLAAGLG--VTIE 275 + + + ++ L L R +R + V +A L V L + + E Sbjct: 186 ILEDPTKAREMLTSLSELMRYSLR--YSNARQVSLADELTVVDSYLQLASIQFEDRLQFE 243 Query: 276 RHLPEHPVHVMGARDELIQVF--QNLVENACKYGQEGKR--VIIRLSEEDTGNATEVVAS 331 + D + Q LVEN K+G I L V Sbjct: 244 NQINP------AIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGT--VTLE 295 Query: 332 IQDFGPGIAAEHLPRLTERFYRIDVETSRAHKGTGLGLAIVKHILARHRG---RLVVRSQ 388 +++ G + TG GL V+ L G ++ + + Sbjct: 296 VENTGSL------------------ALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEK 337 Query: 389 LGEGSTFMVRLPG 401 G+ MV +PG Sbjct: 338 QGKV-NAMVLIPG 349
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1048 bits (2711), Expect = 0.0 Identities = 462/1036 (44%), Positives = 654/1036 (63%), Gaps = 13/1036 (1%) Query: 1 MNRFFVDRPVFAAVISIVLVLAGLICIRILPVAQYPELTPPQVVVSATYPGASAETVAQT 60 M FF+ RP+FA V++I+L++AG + I LPVAQYP + PP V VSA YPGA A+TV T Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VAAPLEQQINGVENMLYMQSSSLGSGTMQLTVTFALGTDPDQATINVNNRVQRATSSLPQ 120 V +EQ +NG++N++YM S+S +G++ +T+TF GTDPD A + V N++Q AT LPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQRLGVTVDKRSTTILGMVAMFATTDRYDRTYVGNYALLNVVDDLKRLPGVGDVQLLGN 180 EVQ+ G++V+K S++ L + + + + +Y NV D L RL GVGDVQL G Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 IDYSMRVWLRPDRLAQYNLTPSDVSAAIQEQNAQFAAGRFGDQPDPHAGPFTYTATTQGR 240 Y+MR+WL D L +Y LTP DV ++ QN Q AAG+ G P + Q R Sbjct: 181 -QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 241 LPDAAAFENIILRSSSQNAATLRLKDVARVELGTESYLVNSNLNGTPAVPIAIYLQPGAN 300 + F + LR + + + +RLKDVARVELG E+Y V + +NG PA + I L GAN Sbjct: 240 FKNPEEFGKVTLRVN-SDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 301 ALNTMELIQNRMNELKASFPAGIDYAIPFDTTKFIKVSIEEVVHTFIEAIILVVLVVFIF 360 AL+T + I+ ++ EL+ FP G+ P+DTT F+++SI EVV T EAI+LV LV+++F Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 361 LQNWRATLIPVIAVPISIIGTFAGMYVLGFSINLLTLFGLVLAIGIVVDDAIVVLENVER 420 LQN RATLIP IAVP+ ++GTFA + G+SIN LT+FG+VLAIG++VDDAIVV+ENVER Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 IMTTEKLSPRKAAIKAMGEVTGPVIAIVLVLCAVFIPVAFMGGLVGEMYKQFAVTIAISV 480 +M +KL P++A K+M ++ G ++ I +VL AVFIP+AF GG G +Y+QF++TI ++ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 481 TLSGLVALTLTPALCALILKP---GHHEPILPF-RIFNRAFERVTSGYTRGVRFFLKRAT 536 LS LVAL LTPALCA +LKP HHE F FN F+ + YT V L Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 537 IGLIIFAGLLGSTYYLFERVPGSLLPDEDQGFLFGVAVLPPAASLERTTVVLDQVSENIR 596 L+I+A ++ LF R+P S LP+EDQG + LP A+ ERT VLDQV++ Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 597 KNPA--VDNVFAVSGFDLLSGGLKTSAGTMFIMLKDWKERTTPDADARNLPRTIMGMNAG 654 KN V++VF V+GF G +AG F+ LK W+ER + A + Sbjct: 599 KNEKANVESVFTVNGFSF--SGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGK 656 Query: 655 IKDGMVLAFNPPPIMGLSTTGGFELYVQDRTGGGVESLTQATKLITEAAAKRP-ELQGVR 713 I+DG V+ FN P I+ L T GF+ + D+ G G ++LTQA + AA+ P L VR Sbjct: 657 IRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 714 TTFDPYVPQYDIQLDREKAKAMGVPINSVFTAMQATFGSLYVNDFTLYGRNYQVNLQSEA 773 Q+ +++D+EKA+A+GV ++ + + G YVNDF GR ++ +Q++A Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 774 EFRRDPGDLKHVFVRADSGSMIPLDALVTVKRIVGPDQLERFNAFNAAKVTGNPAPGYTS 833 +FR P D+ ++VR+ +G M+P A T + G +LER+N + ++ G APG +S Sbjct: 777 KFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSS 836 Query: 834 GDAIKAMQEVAAQVLPQGYQIAWTGSAYQEVSTSGTGSQAMIFGLIMVFLILAAQYERWS 893 GDA+ M+ +A++ LP G WTG +YQE + + ++VFL LAA YE WS Sbjct: 837 GDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 894 LPLAVITAVPFAIFGALLATDLRGLTNDVYFQIGLVTLIGLAVKNAILIVEFAV-LERES 952 +P++V+ VP I G LLA L NDVYF +GL+T IGL+ KNAILIVEFA L + Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 953 GKSAIEAAASAARLRFRPIVMTSLTFILGVVPLAVSTGAGSASRHSIGTGVIGGMLAATF 1012 GK +EA A R+R RPI+MTSL FILGV+PLA+S GAGS +++++G GV+GGM++AT Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1013 IATFFIPMFYSLIARK 1028 +A FF+P+F+ +I R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031 Score = 90.7 bits (225), Expect = 2e-20 Identities = 82/523 (15%), Positives = 176/523 (33%), Gaps = 35/523 (6%) Query: 528 VRFFLKRATIGLIIFAGLLGSTYYLFERVPGSLLPDEDQGFLFGVAVLPPAASLERTTVV 587 FF++R ++ L+ + ++P + P + A P A + V Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 588 LDQVSENIRKNPAVDNVFAVSGFDLLSGGLKTSAGTMFIMLKDWKERTTPDADARNLPRT 647 + +N+ + + + S SAG++ I L ++ T PD A+ Sbjct: 62 TQVIEQNMNGIDNLMYMSSTS----------DSAGSVTITL-TFQSGTDPD-IAQVQ--- 106 Query: 648 IMGMNAGIKDGMVLAFNPPPIMGLSTTGGFELYVQDRTGGGVESLTQATKLITEAAAKRP 707 + + I ++ + + + + + + + Sbjct: 107 VQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNV--KD 164 Query: 708 ELQGVRTTFDPYV----PQYDIQLDREKAKAMGVPINSVFTAMQA----TFGSLYVNDFT 759 L + D + I LD + + V ++ Sbjct: 165 TLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPA 224 Query: 760 LYGRNYQVNLQSEAEFRRDPGDLKHVFVRAD-SGSMIPLDALVTVKRIVGPDQ-LERFNA 817 L G+ ++ ++ F+ +P + V +R + GS++ L + V+ + R N Sbjct: 225 LPGQQLNASIIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING 283 Query: 818 FNAAKVTGNPAPG---YTSGDAIKAMQEVAAQVLPQG--YQIAWTGSAYQEVSTSGTGSQ 872 AA + A G + AIKA PQG + + + ++S + Sbjct: 284 KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEV-VK 342 Query: 873 AMIFGLIMVFLILAAQYERWSLPLAVITAVPFAIFGALLATDLRGLTNDVYFQIGLVTLI 932 + +++VFL++ + L AVP + G G + + G+V I Sbjct: 343 TLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAI 402 Query: 933 GLAVKNAILIVEFAVLERESGKSAIEAAASAARLRFR-PIVMTSLTFILGVVPLAVSTGA 991 GL V +AI++VE K + A + + + +V ++ +P+A G+ Sbjct: 403 GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGS 462 Query: 992 GSASRHSIGTGVIGGMLAATFIATFFIPMFYSLIARKPPKKHE 1034 A ++ M + +A P + + + +H Sbjct: 463 TGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHH 505
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.9 bits (114), Expect = 4e-08 Identities = 26/134 (19%), Positives = 48/134 (35%), Gaps = 9/134 (6%) Query: 65 VRARVGGILLHRNFVEGTQVKAGEVLFEIDPAPYQAELEKAQAQVAQA--EAQYQQSIRD 122 ++ I+ EG V+ G+VL ++ +A+ K Q+ + QA E Q + Sbjct: 99 IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSR 158 Query: 123 AERAEQLVQQKVQSAAVRDSA-----FATRDLNKAAVAAAKAQLRTAELNLSYTKVTAPI 177 + +L + K+ + L K + + Q ELNL K A Sbjct: 159 SIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL--DKKRAER 216 Query: 178 SGITSQEQVNEGSL 191 + ++ E Sbjct: 217 LTVLARINRYENLS 230 Score = 41.0 bits (96), Expect = 6e-06 Identities = 17/98 (17%), Positives = 38/98 (38%), Gaps = 10/98 (10%) Query: 98 YQAELEKAQAQVAQAEAQYQQSIRDAERAEQLVQQKVQSAAVRDSAFATRDLNKAAVAAA 157 EL ++Q+ Q E++ + + + QL + ++ + + Sbjct: 264 AVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQ---------TTDNIGLL 314 Query: 158 KAQLRTAELNLSYTKVTAPISGITSQEQVN-EGSLIGT 194 +L E + + AP+S Q +V+ EG ++ T Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTT 352
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 114 bits (287), Expect = 5e-34 Identities = 66/202 (32%), Positives = 106/202 (52%) Query: 1 MRRTKAEAAETREAILLAAEQVFLERGVNQSTLTEIACYAGVTRGAIYFHFEDKLDIFQS 60 R+TK EA ETR+ IL A ++F ++GV+ ++L EIA AGVTRGAIY+HF+DK D+F Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 IIGRARFPQEEIMLQAARFDHPNPLHILEQSIVAALELFATDERQQVVFTIINQRCEYVG 120 I + E+ L+ +PL +L + ++ LE T+ER++++ II +CE+VG Sbjct: 62 IWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVG 121 Query: 121 EMAPVIDRLKEMRSNVLALFIGLLKVAERRGELASEWSAETAAQILLAMVGGFLNEWLHG 180 EMA V + + LK L ++ AA I+ + G + WL Sbjct: 122 EMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181 Query: 181 EKGFDLIIHGSRVISTVIQSLR 202 + FDL ++ +++ Sbjct: 182 PQSFDLKKEARDYVAILLEMYL 203
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 29.2 bits (65), Expect = 0.020 Identities = 36/163 (22%), Positives = 61/163 (37%), Gaps = 22/163 (13%) Query: 74 GTVEDIVSLWHPGLA--GPQLRSLIEKYDAYCIAEGARSAIAIEAVHETLAVLRG----- 126 GT E ++ L G+ PQL L++KY G + + + + +L Sbjct: 94 GTAEKLIGLTERGVTIFAPQLDKLLQKYQKAGNILGGGAENIGDNLGKAGGILSTFQNFL 153 Query: 127 ----AGYRLGIATNDSEAGARVT----AKALGIDHLFDVMIG--YDTAARPKPFPDPLLY 176 + ++ ++G V+ AKA I+ L + ++ F L Sbjct: 154 GTALSSMKIDELIKKQKSGGNVSSSELAKA-SIE-LINQLVDTVASLNNNVNSFSQQLNT 211 Query: 177 FAEKLGLSPHEIAMVGDNLHDLETAHAAGAGLAV--GVLSGNS 217 L + H + VG+ L +L GAGL G+LS S Sbjct: 212 LGSVLSNTKH-LNGVGNKLQNLPNLDNIGAGLDTVSGILSAIS 253
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.0 bits (83), Expect = 2e-04 Identities = 19/96 (19%), Positives = 32/96 (33%), Gaps = 2/96 (2%) Query: 259 GLVTPLSHVEMIRAPEGGMVL-FHVAPGDVVEAGAKLATVVTRPGEPEGDIAITAPQAGR 317 G +T + I+ E +V V G+ V G L + E + ++ R Sbjct: 88 GKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQAR 147 Query: 318 ILTRRSLRYVRRGDDLLKLLADKPSAVKKRAGALEA 353 L + + + R +L KL K E Sbjct: 148 -LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEE 182
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 44.2 bits (104), Expect = 2e-09 Identities = 12/39 (30%), Positives = 24/39 (61%) Query: 28 NRRLILDAALDVFLAYGFRGSTIDQIAEKAGMSKPNLLY 66 R+ ILD AL +F G +++ +IA+ AG+++ + + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYW 50
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 42.8 bits (101), Expect = 2e-06 Identities = 29/94 (30%), Positives = 38/94 (40%), Gaps = 16/94 (17%) Query: 9 VIKGGTVITADRTFRADILIEDDKIAAIG-----DSLEGD--------EVIDASGCYVMP 55 VI ++ +ADI ++D +IAAIG D G EVI G V Sbjct: 71 VITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAGEGKIVTA 130 Query: 56 GGIDPHTHLQMPFMGTYSSDDFDTGTAAALAGGT 89 GG+D H H P + +G L GGT Sbjct: 131 GGMDSHIHFICP---QQIEEALMSGLTCMLGGGT 161
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 698 bits (1804), Expect = 0.0 Identities = 293/1033 (28%), Positives = 495/1033 (47%), Gaps = 30/1033 (2%) Query: 14 LFIRRPVFAFVINILIVVAGLAAFTGVDIRELPDVDRPVITISTDFSGASAETIDRQVTQ 73 FIRRP+FA+V+ I++++AG A + + + P + P +++S ++ GA A+T+ VTQ Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 74 VLENAVARVSGVKSISSTS-SFERSRVTVEFNDGVDLNVAAADMRDAISRVANNLPEEAD 132 V+E + + + +SSTS S +T+ F G D ++A +++ + LP+E Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 133 PSRIIKADSNADPVMRLAVTSDTMAV--DDMTVLVEDQIEDVLSAVPGVADVQINGDRDK 190 I S++ +M SD DD++ V ++D LS + GV DVQ+ G Sbjct: 124 QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQY 182 Query: 191 IFRIDIDQARLASYGLTIADISNALSSMGLDAPAGSLRSSDQ------SIVVRATANLEK 244 RI +D L Y LT D+ N L AG L + + + A + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 245 PEDFENVYIKGRTQ-----IRDVATVTLGPDIESSAVRSNSKTAIGLGIVRQAQSNTLDI 299 PE+F V ++ + ++DVA V LG + + R N K A GLGI +N LD Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 300 SQGVRAAVANLQKTLPEGVSIAVTSDDANFINGAIHEVEIALIASVIIVVAIIFMFLWDA 359 ++ ++A +A LQ P+G+ + D F+ +IHEV L ++++V ++++FL + Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 360 RATLIPALSMPAALIGTIAAIYLVGFSVNILTLLALVLATGLVVDDAIVVLENVVSR-RN 418 RATLIP +++P L+GT A + G+S+N LT+ +VLA GL+VDDAIVV+ENV Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 419 QGMGPRAAAVLGTQEVFFAVIATTLTLAAVFVPISFLPGQAGGLFREFGFVLAIAVLLSS 478 + P+ A ++ A++ + L+AVF+P++F G G ++R+F + A+ LS Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 479 VVALTLCPMLASRFLKEASATVESEGHGPLFLR--RIGGGLANFYRKTLHACLSAPFIVV 536 +VAL L P L + LK SA E G F N Y ++ L + + Sbjct: 483 LVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 537 LVAVLFAGASYVGYGLIRQELTPSEDRAVALLRINGPQGISVEFLQSQLDKIEEAI--QP 594 L+ L V + + P ED+ V L I P G + E Q LD++ + Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 595 LRDSGEITTTYAIAGSGGSSNNGFVVLTRAPWKERQR---SQQEIMADITNRIKGITAVR 651 + + T + SG + N G ++ PW+ER S + ++ + I Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 652 VFTTQP---NSLGIRGAGNGLQFAIVGGEYAKLQPAAQAVVAALEKDP-RFVQPRLSVEP 707 V LG + G + L A ++ + P V R + Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 708 TQAQISVEINRERASDLGIDITGLANAVQAVLDGRKIGSVYVGDRSFDVKRVSTTNPIND 767 AQ +E+++E+A LG+ ++ + + L G + R + + Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 768 PTDLENIFMKTADGRYVPMSSIASVVEKAVPPQLNRELRQRSVAITTNLRDDFALGNAFA 827 P D++ +++++A+G VP S+ + P+L R S+ I + G+A A Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 828 AAQEIAAPLLPPGSHIIPLAEASTLSETSSGMAIVFGFAIVIILLVLAAQFESFISALIV 887 + +A+ LP G + + + + + V++ L LAA +ES+ + V Sbjct: 842 LMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSV 900 Query: 888 MATVPLGLGCAVFAMILTGTSLNVYSQIGLVLLVGIMAKNGILIVEFADQLRDK-GLNVR 946 M VPLG+ + A L +VY +GL+ +G+ AKN ILIVEFA L +K G V Sbjct: 901 MLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVV 960 Query: 947 EAIEEAANIRLRPVCMTMICAVLGGVPLVLASGAGAEARVALGWVIVGGLGLATIATLYV 1006 EA A +RLRP+ MT + +LG +PL +++GAG+ A+ A+G ++GG+ AT+ ++ Sbjct: 961 EATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFF 1020 Query: 1007 TPVAYLLLGRFTK 1019 PV ++++ R K Sbjct: 1021 VPVFFVVIRRCFK 1033 Score = 114 bits (286), Expect = 1e-27 Identities = 81/507 (15%), Positives = 176/507 (34%), Gaps = 36/507 (7%) Query: 9 GGSTALFIRRPVFAFVINILIVVAGLAAFTGVDIRELPDVDRPVITISTDF-SGASAETI 67 S + +I LIV + F + LP+ D+ V +GA+ E Sbjct: 527 TNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERT 586 Query: 68 DRQVTQVLENAVARVS-GVKSISSTSSFERSRVTVEFNDGV-----------DLNVAAAD 115 + + QV + + V+S+ + + F S D N A A Sbjct: 587 QKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAV 646 Query: 116 MRDAIS-----RVANNLPEEADPSRIIKADSNADPVMRLAVTSDTMAVDDMTVLVEDQIE 170 + A R +P + + D + + + D +T + Sbjct: 647 IHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFEL---IDQAGLGHDALTQARNQLLG 703 Query: 171 DVLSAVPGVADVQINGDRDKI-FRIDIDQARLASYGLTIADISNALSSMGLDAPAGSLRS 229 + V+ NG D F++++DQ + + G++++DI+ +S+ Sbjct: 704 MAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763 Query: 230 SDQS--IVVRA-TANLEKPEDFENVYIKGRT----QIRDVATVTLGPDIESSAVRSNSKT 282 + + V+A PED + +Y++ T R N Sbjct: 764 RGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRL-ERYNGLP 822 Query: 283 AIGLGIVRQAQSNTLDISQGVRAAVANLQKTLPEGVSIAVTSDDANFINGAIHEVEIALI 342 ++ + +++ D A + NL LP G+ T + ++ + Sbjct: 823 SMEIQGEAAPGTSSGD----AMALMENLASKLPAGIGYDWTGMSYQERL-SGNQAPALVA 877 Query: 343 ASVIIVVAIIFMFLWDARATLIPALSMPAALIGTIAAIYLVGFSVNILTLLALVLATGLV 402 S ++V + + L +P ++G + A L ++ ++ L+ GL Sbjct: 878 ISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLS 937 Query: 403 VDDAIVVLENVVS-RRNQGMGPRAAAVLGTQEVFFAVIATTLTLAAVFVPISFLPGQAGG 461 +AI+++E +G G A ++ + ++ T+L +P++ G G Sbjct: 938 AKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSG 997 Query: 462 LFREFGFVLAIAVLLSSVVALTLCPML 488 G + ++ ++++A+ P+ Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVF 1024 Score = 91.1 bits (226), Expect = 1e-20 Identities = 82/527 (15%), Positives = 186/527 (35%), Gaps = 46/527 (8%) Query: 532 PFIVVLVAVLFAGASYVGYGLIRQELTPSEDRAVALLRINGPQGISVEFLQSQL-DKIEE 590 P ++A++ A + + P+ + N P G + +Q + IE+ Sbjct: 9 PIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQVIEQ 67 Query: 591 AIQPLRDSGEITTTYAIAGSGGSSNNGFVVLTRAPWKERQRSQQEIMADITNRIKGITAV 650 + + + + + + S GS + LT + +Q ++ + A Sbjct: 68 NMNGIDN---LMYMSSTSDSAGSVT---ITLTFQSGTDPDIAQVQVQNKLQL------AT 115 Query: 651 RVFTTQPNSLGIRGAGNGLQFAIVGGEYAKLQPAAQAVVAALEKDPRFVQPRLSVEP--- 707 + + GI + + +V G + Q ++ V+ LS Sbjct: 116 PLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVA--SNVKDTLSRLNGVG 173 Query: 708 ------TQAQISVEINRERASDLGIDITGLANAVQA----VLDGRKIGSVYVGDRSFDVK 757 Q + + ++ + + + + N ++ + G+ G+ + + + Sbjct: 174 DVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 758 RVSTTNPINDPTDLENIFMKT-ADGRYVPMSSIASVVE-KAVPPQLNRELRQRSVAITTN 815 ++ T +P + + ++ +DG V + +A V + R + + + Sbjct: 234 IIAQTR-FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 816 LRDDFALGNAFAAAQEIAA------PLLPPGSHIIPLAEASTLSETS-SGMAIVFGFAIV 868 L NA A+ I A P P G ++ + + + S + AI+ Sbjct: 293 LATG---ANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIM 349 Query: 869 IILLVLAAQFESFISALIVMATVPLGLGCAVFAMILTGTSLNVYSQIGLVLLVGIMAKNG 928 ++ LV+ ++ + LI VP+ L + G S+N + G+VL +G++ + Sbjct: 350 LVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDA 409 Query: 929 ILIVE-FADQLRDKGLNVREAIEEAANIRLRPVCMTMICAVLGGVPLVLASGAGAEARVA 987 I++VE + + L +EA E++ + + + +P+ G+ Sbjct: 410 IVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ 469 Query: 988 LGWVIVGGLGLATIATLYVTPVAYLLLGRFTKPKVEEEERLERELVR 1034 IV + L+ + L +TP L KP E + Sbjct: 470 FSITIVSAMALSVLVALILTPA---LCATLLKPVSAEHHENKGGFFG 513