>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 38.0 bits (88), Expect = 1e-04 Identities = 21/104 (20%), Positives = 32/104 (30%), Gaps = 4/104 (3%) Query: 260 DRLAPSALEATQIRPLATPQGSPRASNPPPAEPAPMPPADLGGLQPVSIQLPPVTPSAGG 319 +AP+ LE Q P+ P P EP P PP + + P P Sbjct: 53 TMVAPADLEPPQ-AVQPPPE--PVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVK 109 Query: 320 ATPPPPPPSQAA-KPPSPPPPPLPPAKPRAGGSRTPLIAAAAAA 362 P + P+ P PA+P + + + Sbjct: 110 KVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSV 153 Score = 30.3 bits (68), Expect = 0.031 Identities = 22/111 (19%), Positives = 30/111 (27%), Gaps = 9/111 (8%) Query: 261 RLAPSALEATQIRPLATPQGSP---------RASNPPPAEPAPMPPADLGGLQPVSIQLP 311 A + P P+ P P +P P P + + + Sbjct: 63 PQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVE 122 Query: 312 PVTPSAGGATPPPPPPSQAAKPPSPPPPPLPPAKPRAGGSRTPLIAAAAAA 362 S T P P S A + P + PRA P A A A Sbjct: 123 SRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQA 173
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 74.2 bits (182), Expect = 1e-16 Identities = 40/138 (28%), Positives = 60/138 (43%), Gaps = 16/138 (11%) Query: 318 AQRVAVEDAVDRSVVTIRGDELFASASASVRDEFQPLLLRIADALRKVK---GQVLVTGH 374 A A V T++ D LF A+++ E Q L ++ L + G V+V G+ Sbjct: 201 APAPAPAPEVQTKHFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGY 260 Query: 375 SDNRPIATLRYPSNWKLSQARAQEVADLLGATTGDAGRFTAEGRSDTEPVASNANAEGRA 434 +D + Y N LS+ RAQ V D L + A + +A G ++ PV N + Sbjct: 261 TDRI--GSDAY--NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQ 316 Query: 435 R---------NRRVEITV 443 R +RRVEI V Sbjct: 317 RAALIDCLAPDRRVEIEV 334
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.1 bits (65), Expect = 0.032 Identities = 28/131 (21%), Positives = 47/131 (35%), Gaps = 6/131 (4%) Query: 228 LAPYYL--EQGWSAQESGLLLGFLTAMEV-LSGLLAPALASRSRDRRPVLVGLTALMLAG 284 + PY + S E G ++ F M V + G + L R R VL + Sbjct: 278 MVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDR-RGPLYVLNIGVTFLSVS 336 Query: 285 FLGLAWAPASLPLLWALCLGLGIGGLFPMGLIVC--LDHFDAPQRAGQLAALVQGAGYLI 342 FL ++ + + + +GGL ++ + Q AG +L+ +L Sbjct: 337 FLTASFLLETTSWFMTIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLS 396 Query: 343 AGVSPWIAGLL 353 G I G L Sbjct: 397 EGTGIAIVGGL 407
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.8 bits (61), Expect = 0.026 Identities = 10/36 (27%), Positives = 15/36 (41%) Query: 48 RVAVPAEGYDELVEGLQGLSSHGIRVLLAESGIEPV 83 P + E G+ L I A+SGI+P+ Sbjct: 444 ATLTPVKATPETYPGVITLPEDLIIGFPADSGIKPI 479
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.022 Identities = 16/66 (24%), Positives = 26/66 (39%), Gaps = 4/66 (6%) Query: 118 GLPRPARLLPVPLAPRRERRRGFNQAQQLAERLAGEL----DLHCDPHSLRRVLDTPAQQ 173 G + A + V L P ER N A+ + R EL D P ++ +++ Sbjct: 618 GQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTAT 677 Query: 174 GLDATV 179 G D + Sbjct: 678 GFDFEL 683
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 3e-04 Identities = 9/41 (21%), Positives = 21/41 (51%) Query: 36 SVIGLIEVMKQFSEVQAGQAGILQAFHVEDGEAIEPGQVLA 76 + G + + E++ + I++ V++GE++ G VL Sbjct: 85 TANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLL 125
>PF07132#Harpin protein (HrpN) Length = 356 Score = 31.6 bits (71), Expect = 0.012 Identities = 23/57 (40%), Positives = 30/57 (52%) Query: 621 GSLAGAALGASIGSVVPVVGTLIGGLVGGAIGAWGGSELGGRLGRSLAGDPPAASDN 677 GS+ G LG +G + +G L GGL+GG +G GS LG LG +L G A Sbjct: 62 GSMMGGGLGGGLGGLGSSLGGLGGGLLGGGLGGGLGSSLGSGLGSALGGGLGGALGA 118
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 31.7 bits (71), Expect = 5e-04 Identities = 14/49 (28%), Positives = 25/49 (51%), Gaps = 2/49 (4%) Query: 51 LEALLDEQQRALAAVRASAERRAKDVEQALGEARAQAAEQYAAAVRLLQ 99 L+ ++ A A++ A+A +A+ EQA EA+ +A EQ + Sbjct: 200 LQIRMNTLTAAKASIEAAAANKAR--EQAAAEAKRKAEEQARQQAAIRA 246
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 39.2 bits (91), Expect = 1e-06 Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 76 RSTWAAQDVCYLEDLYVSPDVRGQQIGKQLIEYVRRQAEERRCARLYWHTQESNHRAQRL 135 RS W +ED+ V+ D R + +G L+ A+E L TQ+ N A Sbjct: 83 RSNW--NGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHF 140 Query: 136 Y 136 Y Sbjct: 141 Y 141
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (299), Expect = 6e-35 Identities = 75/258 (29%), Positives = 117/258 (45%), Gaps = 32/258 (12%) Query: 5 RTALVTGATRGIGLALARRLAASGWSVVGI-----------------ARHASDDFPGRLL 47 + A +TGA +GIG A+AR LA+ G + + ARHA + FP Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHA-EAFP---- 63 Query: 48 CCDLADPAQTAETLRGLLSESA-VDALVNNAGIALPQSLENLDLAALQQVFDLNVRVAVQ 106 D+ D A E + E +D LVN AG+ P + +L + F +N Sbjct: 64 -ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 107 LAQACLPGLKRSPAGRIVNLCSRAIHGAR-ERTAYAAAKSALVGVTRTWALELAPLGITV 165 +++ + +G IV + S R AYA++K+A V T+ LELA I Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 166 NAVAPGPIETELFRQTRPVGGEEERRILST-------IPMQRLGRPDEVAALIEFLLSEG 218 N V+PG ET++ E+ I + IP+++L +P ++A + FL+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 219 ASFVTGQVIGVDGGGSLG 236 A +T + VDGG +LG Sbjct: 243 AGHITMHNLCVDGGATLG 260
>PF04335#VirB8 type IV secretion protein Length = 227 Score = 29.8 bits (67), Expect = 0.011 Identities = 13/43 (30%), Positives = 19/43 (44%), Gaps = 3/43 (6%) Query: 7 RRRRLRAWGLLAGALLLALA---ALASLALGSRPVPLAVTLDA 46 R + AW + A LA A A+A+L P +T+D Sbjct: 29 ERSKKLAWVVAGVAGALATAGVVAVAALTPLKTVEPYVITVDR 71
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 37.6 bits (87), Expect = 4e-05 Identities = 53/289 (18%), Positives = 96/289 (33%), Gaps = 28/289 (9%) Query: 2 PTRRRSALPLLALALSLFA-TLAAAGEPKPARIVSTTPSVTGILLAMDAPLVASAATTPS 60 RR L +AL+ L+ A A P RIV+ +LLA+ A T Sbjct: 6 LISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWLPVELLLALGIVPYGVADTINY 65 Query: 61 RLTDAKGFFSQWAKVADQRGVEVLYRNLRFD--IEAVIAQDPDLLVASA---TGADSAAP 115 RL + S+ V+ LR + +E + P +V SA + A Sbjct: 66 RL-----WVSEPPLPDS-----VIDVGLRTEPNLELLTEMKPSFMVWSAGYGPSPEMLAR 115 Query: 116 Y-RAELEAQGVPTLVVDYSKHSWQELATELGRHTGLERQAQAAIQRFDAYTAEVAT-AIA 173 + ++ S E+A L + A+ + +++ + + + Sbjct: 116 IAPGRGFNFSDGKQPLAMARKSLTEMADLLNL----QSAAETHLAQYEDFIRSMKPRFVK 171 Query: 174 PPQGPVSVVGYNIAGSYSIGRQASPQARLLEALGFRVAELPEALAGKVTRASDFQFISRE 233 P+ + + S +L+ G +P A G+ +S + Sbjct: 172 RGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYG-----IPNAWQGETNFWG-STAVSID 225 Query: 234 NLPAAIAGDSVFLLGASDDDVQAFLADPVLANLSAVREKRVYALGPSSF 282 L A D + + D+ A +A P+ + VR R + F Sbjct: 226 RLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWF 274
>DPTHRIATOXIN#Diphtheria toxin signature. Length = 567 Score = 30.9 bits (69), Expect = 0.004 Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 11/73 (15%) Query: 17 RVIGACLLGGLLAAGAPAQAEEATGNARWVSDSLTTFVRS------GPTDGYRIVGTLTS 70 ++ + L+G LL GAP A + V DS +FV G GY V ++ Sbjct: 11 KLFASILIGALLGIGAPPSAHAGADD---VVDSSKSFVMENFSSYHGTKPGY--VDSIQK 65 Query: 71 GQKVELLGTQGNY 83 G + GTQGNY Sbjct: 66 GIQKPKSGTQGNY 78
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 127 bits (319), Expect = 2e-37 Identities = 75/262 (28%), Positives = 126/262 (48%), Gaps = 14/262 (5%) Query: 11 LSSRVALVTGAGRGIGRGIALALARAGADVAVADLDPQVAEETAAAIRSLGRRSLALGVD 70 + ++A +TGA +GIG +A LA GA +A D +P+ E+ +++++ R + A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 71 VSDGDSVRAMVERVATEFGRLDVAVNNAGVISIRKVAELSLADWDRVMNVNARGVFLCCQ 130 V D ++ + R+ E G +D+ VN AGV+ + LS +W+ +VN+ GVF + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 131 AELPLMQAQRWGRIVNLSSIAGKVGLPDLAHYCASKFAVIGFSNALAKEVARDGVTVNAL 190 + M +R G IV + S V +A Y +SK A + F+ L E+A + N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 191 CPGIVGTGM----WRGEDGLSGRWRQAGESEAQSWERHQASLLPQGEAQTVEDMGQLVVY 246 PG T M W E+G + + E+ +P + D+ V++ Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTG--------IPLKKLAKPSDIADAVLF 237 Query: 247 LAC--APHVTGQAIAVDGGFSL 266 L A H+T + VDGG +L Sbjct: 238 LVSGQAGHITMHNLCVDGGATL 259
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 339 bits (871), Expect = e-112 Identities = 134/390 (34%), Positives = 192/390 (49%), Gaps = 59/390 (15%) Query: 273 FDLDALHAAADQAPCLLRGQAGELHVRLSAPRAKARRLEREVPDDAAL---DPRIAESLR 329 FDL L +A L+ P+ + +LE + D L + E R Sbjct: 106 FDLTELIGIIGRA--------------LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYR 151 Query: 330 LAVRVKDRNLPVLIQGETGAGKEVFARQLHQASARRDKPFVALNCAAIPESLIESELFGY 389 + R+ +L ++I GE+G GKE+ AR LH RR+ PFVA+N AAIP LIESELFG+ Sbjct: 152 VLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH 211 Query: 390 VGGAFTGAAAKGMRGLLQQADGGTLFLDEIGDMPLGLQTRLLRVLAEGEVAPLGAARRQA 449 GAFTGA + G +QA+GGTLFLDEIGDMP+ QTRLLRVL +GE +G Sbjct: 212 EKGAFTGAQTRST-GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIR 270 Query: 450 VDIQVICATHRDLAALVAAGGFREDLYFRLGGARFELPPLRERSDRLALIRRILDEETAH 509 D++++ AT++DL + G FREDLY+RL LPPLR+R++ + + R ++ Sbjct: 271 SDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEK 330 Query: 510 CGVRI-ELGEAALECLLGYRWPGNVRQLRHVLRYACALCGGATLQLADLPAELRGEGRTP 568 G+ + + ALE + + WPGNVR+L +++R AL + + ELR E P Sbjct: 331 EGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSE--IP 388 Query: 569 ASACESGGGP--------------------------------------ERDALLDALVRH 590 S E E +L AL Sbjct: 389 DSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTAT 448 Query: 591 RWKPMAAARELGISRATLYRRVRRHGIRMP 620 R + AA LG++R TL +++R G+ + Sbjct: 449 RGNQIKAADLLGLNRNTLRKKIRELGVSVY 478
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.009 Identities = 41/184 (22%), Positives = 65/184 (35%), Gaps = 5/184 (2%) Query: 144 SAALRNAQQLLLAANASQDATLQNTFALAAQAYYDALAAQRSLAASRQVAELAAQNLEAA 203 +A + AA A++ A L+ A A ++L A + E LE A Sbjct: 209 DSAKIKTLEAEKAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKA 268 Query: 204 DAKY---RAGAAALSDRLQAQTALSQASLAQVRDEGALSNALGVIALRMGLAPDTPLRLS 260 +A L+A+ A +A A + + + NA +LR L + Sbjct: 269 LEGAMNFSTADSAKIKTLEAEKAALEAEKADLEHQSQVLNA-NRQSLRRDLDASREAKKQ 327 Query: 261 GELEAQPDTVFVKAIDEMLAEARREHPALLAAQARLKAAAASVEESRAAGRPSLA-LSAN 319 E E Q K + RR+ A A+ +L+A +EE S L + Sbjct: 328 LEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRD 387 Query: 320 LARS 323 L S Sbjct: 388 LDAS 391
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 158 bits (401), Expect = 8e-46 Identities = 79/431 (18%), Positives = 175/431 (40%), Gaps = 55/431 (12%) Query: 22 RPVSFTFLTLLAAVMALLVVGF--FLFGSYTKRSTVSGQLVPASGQVKVHAPQAGIVLRK 79 PVS + +M LV+ F + G +T +G+L + ++ + IV Sbjct: 51 TPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 80 FVQEGQAVRRGERLMVLSSERYGSDAGPVQAG--ISRRLEQRRDSLRDELEKLRRLQDD- 136 V+EG++VR+G+ L+ L++ +D Q+ +R + R L +E + + Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 137 ------------------------------ERDSLTSKVASLQRELTTLAAQTDSQRRLL 166 ++ + + E T+ A+ + L Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 167 ALASDAAARYQGLMDKGYISMDQLQQRQAELLGQRQTLQGLERERTSLRQQLTERRNELA 226 + + L+ K I+ + +++ + + L+ + + + ++ + E Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 227 GLSAR----QANQLAETRRQLSAVEQDLAESEAKRTLL-VTAPESGIATAVLAEA-GQTV 280 ++ ++L +T + + +LA++E ++ + AP S + G V Sbjct: 291 LVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVV 350 Query: 281 DSSRPLLSIVPADTPLQAELYAPSKSIGFIRPGDAVLIRYQAYPYQKFGQYHGKVQSISR 340 ++ L+ IVP D L+ +K IGFI G +I+ +A+PY ++G GKV++I+ Sbjct: 351 TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Query: 341 ASVSYAELSSMVGGVPGLGQDGEQLYRLRVTLDDQAVTAYGQPRPLQSGMLLDADILQDT 400 ++ Q ++ + +++++ ++ + PL SGM + A+I Sbjct: 411 DAI--------------EDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGM 456 Query: 401 RRLYEWVLEPL 411 R + ++L PL Sbjct: 457 RSVISYLLSPL 467
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 29.0 bits (65), Expect = 0.029 Identities = 8/39 (20%), Positives = 14/39 (35%) Query: 232 RIRLRRADGQMTQLGHLVESIASDSPALVTNEKGQPMTE 270 ++ +R A+G+M S + G P E Sbjct: 787 KLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSME 825
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 24.0 bits (51), Expect = 0.046 Identities = 11/43 (25%), Positives = 18/43 (41%) Query: 9 PPGYRPTPLATLGQQLVRLGQAMQNPNTKLGELTELVQACGVD 51 P PL + + L +G A+Q N KL + + + G Sbjct: 105 GPAKNLAPLDVINRSLTIVGNALQQKNQKLLLNQKKITSLGAK 147
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.010 Identities = 18/75 (24%), Positives = 30/75 (40%), Gaps = 7/75 (9%) Query: 262 KRLEDQLKAAQAEVEALRAELQSQRERNTELIFKLGSATNGWGRCEKER-------DAAL 314 LE Q + A ++LR +L + RE +L + E R DA+ Sbjct: 298 ADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASR 357 Query: 315 ARAAELEGKLAELEK 329 +LE + +LE+ Sbjct: 358 EAKKQLEAEHQKLEE 372
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.6 bits (64), Expect = 0.027 Identities = 11/28 (39%), Positives = 15/28 (53%) Query: 119 SLMLLGTMGTGKTHLACAIIQQVLRTEG 146 +LM+ G GTGK +A A+ R G Sbjct: 162 TLMITGESGTGKELVARALHDYGKRRNG 189
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 41.1 bits (96), Expect = 6e-07 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 7/54 (12%) Query: 4 RSRGFTLVELMVIVVLLGV---MVAFAIPSFVNLIKGNSTASARNDLQKSLDYA 54 R RGFTL+E+M+I++L+GV MV A P+ + +S A + L + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPA----SRDDSAAQTLARFEAQLRFV 51
>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature. Length = 1147 Score = 31.2 bits (70), Expect = 0.021 Identities = 62/286 (21%), Positives = 102/286 (35%), Gaps = 54/286 (18%) Query: 453 AKNTGIVDWVANQLNDVAKSINTATTLVKKGEGSLTA---------TLAAEKARQEQIVK 503 AKNTG D V D+ KS+ L K+ E L + A +++++I Sbjct: 598 AKNTGNYDEVKKAQKDLEKSLRKREHLEKEVEKKLESKSGNKNKMEAKAQANSQKDEIFA 657 Query: 504 RQN-----DALKRAREQNVADLQSEVVRTKALLEQSTKNLND--------------ALSR 544 N DA A QN+ ++ E+ LE KNL D S+ Sbjct: 658 LINKEANRDARAIAYAQNLKGIKRELSDK---LENVNKNLKDFDKSFDEFKNGKNKDFSK 714 Query: 545 QADVRKEFADLVKGIQATP-----------------TSGTQTFGDATAAQASARNALT-A 586 + K VK + P + F T A++ N++ Sbjct: 715 AEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNKDFSKVTQAKSDLENSVKDV 774 Query: 587 GNNQKAIEEARRALQILQQLKDAGANSYGFEGVAKEVERIANKAAEVEAGNAKAADDVNR 646 NQK ++ Q + K G F V + + + N + E A A+ + +N Sbjct: 775 IINQKVTDKVDNLNQAVSVAKATG----DFSRVEQALADLKNFSKEQLAQQAQKNESLNA 830 Query: 647 LNLADLEERIK-AVQNVEVSFGMDFESAETLKQQVADIAAGLAEQL 691 +++ + +K V V G+ A TL + +DI L +L Sbjct: 831 RKKSEIYQSVKNGVNGTLVGNGLSQAEATTLSKNFSDIKKELNAKL 876
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 30.0 bits (67), Expect = 0.008 Identities = 13/49 (26%), Positives = 19/49 (38%) Query: 16 PRLPFELPAPPRPHLPMPAPRPLPRPAPGALPRPVPRPMPVPQTLPRTE 64 P E P P P P+ P P+P P+P+ Q P+ + Sbjct: 65 PEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRD 113 Score = 28.0 bits (62), Expect = 0.030 Identities = 13/48 (27%), Positives = 16/48 (33%) Query: 10 PLPRMGPRLPFELPAPPRPHLPMPAPRPLPRPAPGALPRPVPRPMPVP 57 P P E P P P P+P P P+PV + P Sbjct: 63 PPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQP 110
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 220 bits (563), Expect = 2e-66 Identities = 116/460 (25%), Positives = 204/460 (44%), Gaps = 47/460 (10%) Query: 10 KRRTFAIISHPDAGKTTITEKLLLMGKAIAVAGTVKSRKSDRHATSDWMEMEKQRGISIT 69 K +++H DAGKTT+TE LL AI G+V +D +E+QRGI+I Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGT----TRTDNTLLERQRGITIQ 57 Query: 70 TSVMQFPYREHMINLLDTPGHEDFSEDTYRTLTAVDSALMVLDGGKGVEPRTIALMEVCR 129 T + F + +N++DTPGH DF + YR+L+ +D A++++ GV+ +T L R Sbjct: 58 TGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALR 117 Query: 130 LRDTPIVSFINKLDRDIRDPIELLDEIEAVLKIKAAPITWPIGCYKDFKGVYHLADDRII 189 P + FINK+D++ D + +I+ L + V + + Sbjct: 118 KMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQ----------KVELYPNMCVT 167 Query: 190 VYVPGHGHERIETKVIEKLDSDEARAHLGDLYDNFVEELELVQGACHEFDKDAFLKGEMT 249 + E+ +T VIE D DL + ++ L + + F + Sbjct: 168 NFTES---EQWDT-VIEGND---------DLLEKYMSGKSLEALELEQEESIRFHNCSLF 214 Query: 250 PVFFGTALGNFGVDQVLDCIVDWAPQPLSRATHERSVEPTEEKFSGFVFKIQANMDPKHR 309 PV+ G+A N G+D +++ I + R + + G VFKI+ K R Sbjct: 215 PVYHGSAKNNIGIDNLIEVITNKFYSSTHRG---------QSELCGKVFKIE--YSEK-R 262 Query: 310 DRIAFMRICSGKYEKGMKMRHVRLGKDVKIADALTFFSSEREQLEEAYAGDIIGLHNHGT 369 R+A++R+ SG +R K +KI + T + E ++++AY+G+I+ L N Sbjct: 263 QRLAYIRLYSGVLHLRDSVRISEKEK-IKITEMYTSINGELCKIDKAYSGEIVILQNEF- 320 Query: 370 IQIGDTFSE---GENFGFTGIPHFAPELFRRVRLKDPLKSKQLRQGLQELAEEGAT-QVF 425 +++ + P P L V P + + L L E+++ + + Sbjct: 321 LKLNSVLGDTKLLPQRERIENPL--PLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYY 378 Query: 426 FPERNNDIILGAVGVLQFDVVASRLKEEYKVECAYEAINV 465 ++IIL +G +Q +V + L+E+Y VE + V Sbjct: 379 VDSATHEIILSFLGKVQMEVTCALLQEKYHVEIEIKEPTV 418
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 6e-09 Identities = 24/160 (15%), Positives = 60/160 (37%), Gaps = 13/160 (8%) Query: 82 RIAVKQAESLVASRKATL-----EMRQLNAR-RRAEMDEMVVSRESRDDAHNTAAAAMAD 135 + AV + E+ L ++ Q+ + A+ + +V++ +++ + + Sbjct: 251 KHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN 310 Query: 136 YEQAKAQLDAARLNLERTRVVAQVDGYVTNLNVHR-GDYARVGEAKMAVI-DKNSYWVYG 193 +L + + + A V V L VH G E M ++ + ++ V Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTA 370 Query: 194 YFEETKLPYIREGDPVDMQLMS-----GEHLKGHVESIAR 228 + + +I G +++ + +L G V++I Sbjct: 371 LVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Score = 49.4 bits (118), Expect = 7e-09 Identities = 21/179 (11%), Positives = 63/179 (35%), Gaps = 16/179 (8%) Query: 13 LLILLVAVFIGRTLW--VNYMDTPWTRDGRVRAD--VINVAADVSGIVVDVPVRDNQLVK 68 + ++ + + + ++ T +G++ + + IV ++ V++ + V+ Sbjct: 60 VAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVR 119 Query: 69 KGDLLMQIDPDHYRIAVKQAESLVASRKATLEMRQLNARRRAEMDEMVVSRESRDDAHNT 128 KGD+L+++ + +S + + R R E++++ + + Sbjct: 120 KGDVLLKLTALGAEADTLKTQSSLLQARLEQT-RYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 129 AAAAM---------ADYEQAKAQLDAARLNLERTRVVAQVDGYVTNLNVHRGDYARVGE 178 + + + Q LNL++ R A+ + +N + Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKR--AERLTVLARINRYENLSRVEKS 235
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 81.0 bits (200), Expect = 1e-18 Identities = 41/180 (22%), Positives = 85/180 (47%), Gaps = 15/180 (8%) Query: 446 TIGPSLGADNIAKGIDASLWGMLFVSLFIIVIY---RF---FGVIATVALAFNMVMLVAL 499 ++GP + + + + + L + +I+ Y RF F + A VAL ++++ V L Sbjct: 142 SVGPKVSGELVWTAVWS-----LLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGL 196 Query: 500 MSILGATLTLPGIAGIVLTMGMAVDANVLIFSRIREEL--ANGMSVQRAIHEGFNRAFTA 557 ++L L +A ++ G +++ V++F R+RE L M ++ ++ N + Sbjct: 197 FAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVNETLSR 256 Query: 558 ILDANLTSLLVGGILYAMGTGPVKGFAVTMSLGIITSMFTAIMVTRAMVNLIFGGRDFKK 617 + +T+LL + G ++GF M G+ T ++++ V A ++F G D K Sbjct: 257 TVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYV--AKNIVLFIGLDRNK 314
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 303 bits (778), Expect = e-105 Identities = 101/299 (33%), Positives = 163/299 (54%), Gaps = 20/299 (6%) Query: 8 INFMGIRNVAFAVTLILTVIALGSWFTKGINFGLDFTGGTLIELTYEQPADLGKVRGQLV 67 +F + F +++ + ++ G+NFG+DF GGT I D+G R L Sbjct: 14 FDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYRAALE 73 Query: 68 GAGYEDAVVQSFGDAR------DVLVRMPSED------------PELGKKVATALQQADA 109 D ++ D ++R+ ++ EL KV TAL D Sbjct: 74 PLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALTAVDP 133 Query: 110 GNPANLKRVEYVGPQVGEELRDQGGLGMLLALGGILLYVGFRFQWKFALGAILSLVHDAI 169 + E VGP+V EL +L A I+ Y+ RF+W+FALGA+++LVHD + Sbjct: 134 A--LKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVL 191 Query: 170 IVMGVLSFFQVTFDLTVLAAVLAVVGYSLNDTIVIFDRVRENFRVLRKADLVENLNISTS 229 + +G+ + Q+ FDLT +AA+L + GYS+NDT+V+FDR+REN + L + +N+S + Sbjct: 192 LTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLSVN 251 Query: 230 QTLLRTIATSVSTLLAIAALLFFGGDNLFGFSIALFVGVMAGTYSSIYIANVVLIWLNL 288 +TL RT+ T ++TLLA+ +L +GGD + GF A+ GV GTYSS+Y+A +++++ L Sbjct: 252 ETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIGL 310
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 28.7 bits (64), Expect = 0.021 Identities = 12/57 (21%), Positives = 30/57 (52%), Gaps = 10/57 (17%) Query: 45 DAVARASGATDILDAARVVDTLEEALSGCSVVLG------TSARDRRIPW----PLL 91 D+++ ++ A+D++ R + T G +++LG +++D +P+ PL+ Sbjct: 342 DSLSSSTQASDVITNQRSIATTVNLRDGQTLLLGGLTDYKNTSQDSGVPFLSKIPLI 398
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 27.0 bits (59), Expect = 0.045 Identities = 20/76 (26%), Positives = 30/76 (39%), Gaps = 5/76 (6%) Query: 103 ELEELQDSADLAGVATFKRRLKAAQAELEREFAACWDDA-----QRREEAERLVRRMQFL 157 EL + + A A +R A E R+ A + A QRR+E ER + Sbjct: 111 SATELAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQ 170 Query: 158 DKLAQEVRQLEERLDD 173 KLA+ + L + Sbjct: 171 LKLAEAEEKRLAALSE 186
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 107 bits (269), Expect = 1e-27 Identities = 77/363 (21%), Positives = 136/363 (37%), Gaps = 56/363 (15%) Query: 22 VGIDLGTTNSLVAAVRSGVAEPLPDAQGRLILPSAVRYHAERAEVGESARAAAAEDPFNT 81 + IDLGT N+L+ G+ L PS V +RA +S A + Sbjct: 13 LSIDLGTANTLIYVKGQGIV---------LNEPSVVAIRQDRAGSPKSVAAVGHD----- 58 Query: 82 VISVKRLMGRGLEDVKQLGEQLPYRFRQGESHMPFIETVQGLKSPV----EVSADILRE- 136 K+++GR + I ++ +K V V+ +L+ Sbjct: 59 ---AKQMLGRTPGN---------------------IAAIRPMKDGVIADFFVTEKMLQHF 94 Query: 137 LRQRAETTLGGELVGAVITVPAYFDDAQRQATKDAARLAGLNVLRLLNEPTAAAVAYGLD 196 ++Q + ++ VP +R+A +++A+ AG + L+ EP AAA+ GL Sbjct: 95 IKQVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLP 154 Query: 197 KGAEGLVAIYDLGGGTFDISILRLTRGVFEVLATGGDTALGGDDFDHAIAGWVIEEAGLS 256 + D+GGGT +++++ L V +GGD FD AI +V G Sbjct: 155 VSEATGSMVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYGSL 209 Query: 257 ADLDPGSQRQLLQIACAAKERLTDEASVR----VAYGDWSGELSRATLDELIEPFVARSL 312 + ++R +I A E VR L+ + E ++ + + Sbjct: 210 IG-EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIV 268 Query: 313 KSCRRAVRDSGVDLEEI---RSVVMVGGSTRVPRVRTAVGELFGCEPLTDIDPDQVVAIG 369 + A+ +L R +V+ GG + + + E G + DP VA G Sbjct: 269 SAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARG 328 Query: 370 AAI 372 Sbjct: 329 GGK 331
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 30.8 bits (69), Expect = 0.004 Identities = 25/124 (20%), Positives = 40/124 (32%), Gaps = 11/124 (8%) Query: 5 QPKRALLVIDVQNEYVSGNLRIEFPAIQSSLERIGAAMDAAYAAGIPIVVVQHLA---PA 61 P RA+L+I Y + I + GIP+V P Sbjct: 27 DPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQNPD 86 Query: 62 D--------SPLFARGSRQAELHEVVASRPYQHKVEKQLASSFVGTGLADWLRERDIDTL 113 D P G + ++ +A + K S+F T L + +R+ D L Sbjct: 87 DRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQL 146 Query: 114 AVVG 117 + G Sbjct: 147 IITG 150
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 32.6 bits (74), Expect = 0.004 Identities = 25/94 (26%), Positives = 38/94 (40%), Gaps = 12/94 (12%) Query: 161 SSLTNTSVGELFLAGVIPGLL--LAAAFMLLNAVYAYRNGLQARHAAPAWGEILAALSGA 218 +L N G + G+L ++A+F+L N + AA A E+ + G Sbjct: 233 PNLDNIGAG----LDTVSGILSAISASFILSN-----ADADTRTKAA-AGVELTTKVLGN 282 Query: 219 LTALIAPVIIVAGIVLGLVTPTESGALIALYVAL 252 + I+ II GL T + LIA V L Sbjct: 283 VGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTL 316
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 28.8 bits (64), Expect = 0.031 Identities = 27/106 (25%), Positives = 42/106 (39%), Gaps = 23/106 (21%) Query: 12 VGTQNRQEAWLEVFYAL--------PLLKPSSEIVAAVAPILGY--AAGNQALTFTSQQA 61 VG R E LE+ + PS E++A +AP G+ + G Q L + Sbjct: 81 VGL--RTEPNLELLTEMKPSFMVWSAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSL 138 Query: 62 YQLADALKGIDAAQSALL----------SRLA-ESQKPLVATLLAE 96 ++AD L AA++ L R +PL+ T L + Sbjct: 139 TEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLID 184
>PF05272#Virulence-associated E family protein Length = 892 Score = 34.3 bits (78), Expect = 4e-04 Identities = 22/99 (22%), Positives = 34/99 (34%), Gaps = 12/99 (12%) Query: 102 IPTTLPEALRLAADQAEQNHALRLVISEQAPKVQALERLSGAAGTMCIT----------D 151 PE + Q L+ E AP + + + T +T D Sbjct: 751 EIYFRPEQELRLVETGVQGRLWALLTREGAPAAEGAAQKGYSVNTTFVTIADLVQALGAD 810 Query: 152 AAKHLKINPSRLFDWLQQNRWIYRR--SGSARWIGYQPR 188 K + ++ DWL +N W Y R SG R +P+ Sbjct: 811 PGKSSPMLEGQVRDWLNENGWEYLRETSGQRRRGYMRPQ 849
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.1 bits (62), Expect = 0.047 Identities = 18/75 (24%), Positives = 24/75 (32%), Gaps = 5/75 (6%) Query: 50 SKRAVQQAIKWLRSAGIVSVEERQGRSTMYSVTPAAYAPLQEMHPSSKCTRAGNAPTPAD 109 S Q WL G + E G+ + P + P ++ A A P D Sbjct: 815 SPMLEGQVRDWLNENGWEYLRETSGQRRRGYMRPQVWPP-----VIAEDKEADQAHAPGD 869 Query: 110 AAPQPPQEMHPTPAA 124 Q P E P A Sbjct: 870 QDQQQPVEPAAAPWA 884
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 41.1 bits (96), Expect = 7e-07 Identities = 19/54 (35%), Positives = 30/54 (55%), Gaps = 7/54 (12%) Query: 4 RSRGFTLVELMVIVVLLGV---MVAFAIPSFVNLIKGNSTASARNDLQKSLDYA 54 R RGFTL+E+M+I++L+GV MV A P+ + +S A + L + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPA----SRDDSAAQTLARFEAQLRFV 51
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 28.2 bits (63), Expect = 0.020 Identities = 15/74 (20%), Positives = 22/74 (29%), Gaps = 7/74 (9%) Query: 27 QYQAVDGGVERLRLSGGAAVQMTHWRKTAITISGSGWIGTGMLGLDFDNPLELRCNASLG 86 Y A GGV+ + + G R+ + G LG D Sbjct: 315 SYAAAMGGVDVIVFTAGIGENGPEIREFILD-------GLEFLGFKLDKEKNKVRGEEAI 367 Query: 87 ISGRTAVDRVFTIP 100 IS + V +P Sbjct: 368 ISTADSKVNVMVVP 381
>YERSSTKINASE#Yersinia serine/threonine protein kinase signature. Length = 732 Score = 32.8 bits (74), Expect = 0.008 Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 5/110 (4%) Query: 63 ILQQAWQRFDWGDDADIALVAVGGYGRGELHPYSDVDLLILLDSEDQESFREPIEGFLTL 122 I++ + QR D + +G R H + +++L+ L + Q E GFL Sbjct: 538 IVEPSLQRIQKHLDQTHSFSDIGSLVRAHKHLETLLEVLVTLSQQGQPVSSETY-GFLNR 596 Query: 123 LWDIGLEVGQSVRSVQQCAEEARADLTVITTLMECRTICGPDSLRQRMLR 172 L + + + Q + ++QQ E A+A L+++ R+ D RQ + R Sbjct: 597 LTEAKITLSQQLNTLQQQQESAKAQLSILIN----RSGSWADVARQSLQR 642
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 37.5 bits (87), Expect = 3e-05 Identities = 17/79 (21%), Positives = 28/79 (35%), Gaps = 15/79 (18%) Query: 132 GEVVIFSAGTGNPFFTT-------------DSAACLRAIEIDADVVLKATKVDGVYTADP 178 G +VI S G G P D A A E++AD+ + T V+G Sbjct: 186 GVIVIASGGGGVPVILEDGEIKGVEAVIDKDLAGEKLAEEVNADIFMILTDVNGAALY-- 243 Query: 179 FKDPNAEKFERLTYDEVLD 197 + + + +E+ Sbjct: 244 YGTEKEQWLREVKVEELRK 262
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 609 bits (1573), Expect = 0.0 Identities = 219/565 (38%), Positives = 340/565 (60%), Gaps = 13/565 (2%) Query: 401 ERLQAIAASPGIASGPAHVQVAQRFEFQPR-GESPAHERERLLRAKRAVDEEIVGLVERS 459 ++ IAAS G+A A + + + + + E E+L A EE+ + +++ Sbjct: 3 HKITGIAASSGVAIAKAFIHLEPNVDIEKTSITDVSTEIEKLTAALEKSKEELRAIKDQT 62 Query: 460 TVKA---IREIFVTHREMLDDPELAEQVQLRL-NRGESAEAAWSRVVEDSAAQQEALHDA 515 EIF H +LDDPEL + ++ ++ N +AE A V + + E++ + Sbjct: 63 EASMGADKAEIFAAHLLVLDDPELVDGIKGKIENEQMNAEYALKEVSDMFVSMFESMDNE 122 Query: 516 LLAERAADLRDLGRRVLARLCGVEAPREPE--QPYILVMDEVGPSDVARLDAQRVAGILT 573 + ERAAD+RD+ +RVL L GVE + +++ +++ PSD A+L+ Q V G T Sbjct: 123 YMKERAADIRDVSKRVLGHLIGVETGSLATIAEETVIIAEDLTPSDTAQLNKQFVKGFAT 182 Query: 574 ARGGATSHSAIIARALGIPALVGAGAAVLGLEPGTALLLDGEHGWLQVAPSTEQLQQAAA 633 GG TSHSAI++R+L IPA+VG ++ G +++DG G + V P+ E+++ Sbjct: 183 DIGGRTSHSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEE 242 Query: 634 ERDARQQRQARADAQRLEPARTRDGHAVEVCANLGDTAGAARAVELGAEGVGLLRTEFVF 693 +R A ++++ EP+ T+DG VE+ AN+G + G EG+GL RTEF++ Sbjct: 243 KRAAFEKQKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY 302 Query: 694 MNNARAPDLATQEAEYRRVLDALDGRPLVARTLDVGGDKPLPYWPIPHEENPYLGLRGIR 753 M+ + P Q Y+ V+ +DG+P+V RTLD+GGDK L Y +P E NP+LG R IR Sbjct: 303 MDRDQLPTEEEQFEAYKEVVQRMDGKPVVIRTLDIGGDKELSYLQLPKELNPFLGFRAIR 362 Query: 754 LTLQRPQILETQLRALFRAAGERPLRVMFPMVGSLDEWRQARDLALRLREEI------PL 807 L L++ I TQLRAL RA+ L+VMFPM+ +L+E RQA+ + ++++ Sbjct: 363 LCLEKQDIFRTQLRALLRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVS 422 Query: 808 ADLQLGIMVEVPSAALLAPVLAREVDFFSVGTNDLTQYTLAIDRGHPSLSAQADGLHPAV 867 +++GIMVE+PS A+ A + A+EVDFFS+GTNDL QYT+A DR + +S HPA+ Sbjct: 423 DSIEVGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLYQPYHPAI 482 Query: 868 LQLIDMTVRAAHAEGKWVGVCGELAADPLALPLLVGLGVDELSVSARSIALVKAGVRELQ 927 L+L+DM ++AAH+EGKWVG+CGE+A D +A+PLL+GLG+DE S+SA SI ++ + +L Sbjct: 483 LRLVDMVIKAAHSEGKWVGMCGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLS 542 Query: 928 LVAARGLARKALGLASAAEVRALVE 952 + A+KAL L +A EV LV+ Sbjct: 543 KEELKPFAQKALMLDTAEEVEQLVK 567
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 108 bits (272), Expect = 5e-28 Identities = 78/362 (21%), Positives = 138/362 (38%), Gaps = 61/362 (16%) Query: 319 RVLILGVNGFIGNHLSERLLRDGRYEVHGMDIGSDAIE-RLK-------ADPHFHFVEGD 370 + L+ G GFIG H+S+RLL G ++V G+D +D + LK A P F F + D Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAG-HQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 371 IGIHSEWLE--YHVKKCDVILPLVAIATPIEYT-RNPLRVFELDFEENLRIVRYCVKYG- 426 + E + + + + + Y+ NP + + L I+ C Sbjct: 61 LADR-EGMTDLFASGHFERVFISPHRLA-VRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 427 KRVVFPSTSEVYGMCQDPDFDEDRSNLVVGPINKQRWIYSVSKQLLDRVIWAYGQ-QGLR 485 + +++ S+S VYG+ + F D S V P++ +Y+ +K+ + + Y GL Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDS--VDHPVS----LYAATKKANELMAHTYSHLYGLP 172 Query: 486 FTLFRPFNWMGPRLDRLDSARIGSSRAITQLILHLVEGTPIRLVDGGAQKRCFTDVDDGI 545 T R F GP R D A ++A+ +EG I + + G KR FT +DD Sbjct: 173 ATGLRFFTVYGPW-GRPDMALFKFTKAM-------LEGKSIDVYNYGKMKRDFTYIDDIA 224 Query: 546 EALARIIDN---------------RDGRCDGQIVNIGNPDNEASIRQLGEELLRQFEAHP 590 EA+ R+ D ++ NIGN + + L Sbjct: 225 EAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVE-LMDYIQALEDALGIEA 283 Query: 591 LRAQFPPFAGFREVESRSFYGDGYQDVAHRKPSIDNARRLLDWQPTIELRETIGKTLDFF 650 + P G DV ++ + P +++ + ++++ Sbjct: 284 KKNMLPLQPG---------------DVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328 Query: 651 LH 652 Sbjct: 329 RD 330
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 69.5 bits (170), Expect = 2e-14 Identities = 34/131 (25%), Positives = 56/131 (42%), Gaps = 7/131 (5%) Query: 787 DAPCILVAEDNPVNQLVVRGFLAKRGYAVRLAGNGRLALDEYLRDPNGIQLILMDGEMPE 846 ILVA+D+ + V+ L++ GY VR+ N L++ D MP+ Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD--LVVTDVVMPD 59 Query: 847 MDGFEATRLIRREERAQGWPRVPIVALTAHILDEHRRAGIEAGMDAYLGKPVDRAELYAT 906 + F+ I++ P +P++ ++A E G YL KP D EL Sbjct: 60 ENAFDLLPRIKKA-----RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114 Query: 907 LERLLGQPSRQ 917 + R L +P R+ Sbjct: 115 IGRALAEPKRR 125
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 28.5 bits (63), Expect = 0.032 Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 1/62 (1%) Query: 160 LGSDDLEGLRVAVQGLGH-VGYALAEQLAAVGAELLVCDLDPGRVQLAVEQLGAHPLAPE 218 + + +EG + G +G A+A LA+ GA + D +P +++ V L A E Sbjct: 1 MNAKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE 60 Query: 219 AL 220 A Sbjct: 61 AF 62
>PF06438#Heme acquisition protein HasAp Length = 205 Score = 276 bits (706), Expect = 1e-97 Identities = 204/205 (99%), Positives = 205/205 (100%) Query: 1 MSISISYSTTYSGWTVADYLADWSAYFGDVNHRPGQVVDGSNTGGFNPGPFDGSQYALKS 60 MSISISYSTTYSGWTVADYLADWSAYFGDVNHRPGQVVDGSNTGGFNPGPFDGSQYALKS Sbjct: 1 MSISISYSTTYSGWTVADYLADWSAYFGDVNHRPGQVVDGSNTGGFNPGPFDGSQYALKS 60 Query: 61 TASDAAFIAGGDLHYTLFSNPSHTLWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLG 120 TASDAAFIAGGDLHYTLFSNPSHTLWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLG Sbjct: 61 TASDAAFIAGGDLHYTLFSNPSHTLWGKLDSIALGDTLTGGASSGGYALDSQEVSFSNLG 120 Query: 121 LDSPIAQGRDGTVHKVVYGLMSGDSSALQGQIDALLKAVDPSLSINSTFDQLAAAGVAHA 180 LDSPIAQGRDGTVHKVVYGLMSGDSSALQGQIDALLKAVDPSLSINSTFDQLAAAGVAHA Sbjct: 121 LDSPIAQGRDGTVHKVVYGLMSGDSSALQGQIDALLKAVDPSLSINSTFDQLAAAGVAHA 180 Query: 181 TPAAAAAEIGVVGVQELPHDLALAA 205 TPAAAAAE+GVVGVQELPHDLALAA Sbjct: 181 TPAAAAAEVGVVGVQELPHDLALAA 205
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 417 bits (1073), Expect = e-145 Identities = 96/435 (22%), Positives = 170/435 (39%), Gaps = 8/435 (1%) Query: 15 AALELDEK---RFSRLGWGLVLLGFVGFLLWAGLAPLDKGVGVSGTVMVAGSRKAVQHPT 71 A LEL E R RL ++ V + + L ++ +G + +G K ++ Sbjct: 44 AHLELIETPVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIE 103 Query: 72 GGLVRHIRVHEGERVEAGQVLLEMDATQARAQADGLFAQYLAALASLARLSAERDEKARI 131 +V+ I V EGE V G VLL++ A A A + L A R Sbjct: 104 NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELN 163 Query: 132 EFPAELLALDDPRLPTLLEQQ----RQLHDSRRRALRLELDGLAETVAGSQAQLDGLQAA 187 + P EL D+P + E++ L + + + + +A+ + A Sbjct: 164 KLP-ELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLAR 222 Query: 188 LRSKEQQRAALEEQLRGLRQLASEGYVPRNRLLDSERLLAQVNGEIAGDLGSLGSTRRQI 247 + E + +L L + + ++ +L+ E + E+ L +I Sbjct: 223 INRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEI 282 Query: 248 LELRLRMAQRREKFQEEVRASLADAQVRAEELRNRLASARFDLANSEVRAPVAGLVVGQE 307 L + + F+ E+ L L LA S +RAPV+ V + Sbjct: 283 LSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLK 342 Query: 308 VFTEGGVIAPGQQLMEILPERQPLLVDARLPVEMVDKVRVGLPVELMFSAFNQSTTPRVE 367 V TEGGV+ + LM I+PE L V A + + + + VG + AF + + Sbjct: 343 VHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLV 402 Query: 368 GEVTLVSADRLLDERSEAPYYRVRIRVGEEGVRRLAGLEIRPGMPVEAFVRSGERSLLNY 427 G+V ++ D + D+R + + + + GM V A +++G RS+++Y Sbjct: 403 GKVKNINLDAIEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISY 462 Query: 428 LFKPLADRTHLALGE 442 L PL + +L E Sbjct: 463 LLSPLEESVTESLRE 477
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.007 Identities = 20/171 (11%), Positives = 49/171 (28%), Gaps = 11/171 (6%) Query: 60 LPSLRYDYNKARNDSTVSQGDARVERDYRSYASTLSLEQPLFDYEAYARYRQ-GEAQAL- 117 L +L + + + S++ Q R S + P ++ E + L Sbjct: 127 LTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 118 ---FADEQFRGRSQELA---VRLFAAYSETLFAREQVVLAEAQRRALETQLAFNQRAFEE 171 EQF + + L +E L ++ E R +++L + Sbjct: 187 LTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHK 246 Query: 172 GEGTRTDLLE---TRARLSLTRAEEIAASDRAAAARRTLEAMLGQALEDRE 219 + +LE + ++ + + + + + Sbjct: 247 QAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFK 297
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 56.0 bits (135), Expect = 6e-11 Identities = 25/161 (15%), Positives = 59/161 (36%), Gaps = 17/161 (10%) Query: 41 IVSSKAKGRVQVLHVRRGDEVKQGDLLISLDSPELEAQLDALHAARNQAQAQLDESLHGT 100 + V+ + V+ G+ V++GD+L+ L + EA ++ QA+ + + Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 101 REESIRALKASLAQAEAELRNAESDFQRNQQMVERGFLSRTQFDLSRRERDVARDRVAEA 160 R + L E +N ++++ L + QF + ++ + + Sbjct: 158 RSIELNKLPELKLPDEPYFQNV-----SEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212 Query: 161 RANLDEGLKGDREERRQALQAAVRRADAQIAELQAQIDDLQ 201 RA + A + R + ++++DD Sbjct: 213 RAER------------LTVLARINRYENLSRVEKSRLDDFS 241 Score = 52.9 bits (127), Expect = 7e-10 Identities = 29/205 (14%), Positives = 77/205 (37%), Gaps = 24/205 (11%) Query: 75 LEAQLDALHAARNQAQAQLDESLHGTREESIRALKASLAQAEAELRNAESDFQRNQQMVE 134 ++ Q + Q + LD+ + + A + + E R +S ++ Sbjct: 191 IKEQFSTWQNQKYQKELNLDK-----KRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 135 RGFLSRTQFDLSRRERDVARDRVAEARANLDE------GLKGDREERRQALQAAV----R 184 + +++ + A + + ++ L++ K + + Q + + R Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 185 RADAQIAELQAQI----DDLQ---VRAPVNGEVGPIPA-EQGELINAYSPLLTLVRLDDS 236 + I L ++ + Q +RAPV+ +V + +G ++ L+ +V DD+ Sbjct: 306 QTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 237 YFV-FNLREDILAKVRKGDRIVMQV 260 V ++ + + G +++V Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKV 390
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 28.4 bits (63), Expect = 0.039 Identities = 27/122 (22%), Positives = 50/122 (40%), Gaps = 1/122 (0%) Query: 246 LGYRQSASFFMLLGIVLPFLIAVIALSEFIAELLPTEESVYLTMTFITLPLFYMAGYSWP 305 LGY Q S L ++ +A +L + L P+ + T + P+ +++G +P Sbjct: 139 LGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFP 198 Query: 306 EQAMPDWVRWLADAIPSTWAIRAIAEMNQMDLPLREVSDHALVLLGMAATYALLGTLLYQ 365 +P + A +P + +I I + + P+ +V H L L T L + Sbjct: 199 VDQLPIVFQTAARFLPLSHSIDLIRPI-MLGHPVVDVCQHVGALCIYIVIPFFLSTALLR 257 Query: 366 YR 367 R Sbjct: 258 RR 259
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 55.7 bits (134), Expect = 5e-12 Identities = 21/71 (29%), Positives = 33/71 (46%) Query: 151 RSAILEDMVVDRHARGQGVGRELIGRAVERARSWGCYKLALSSHQDRETAQRFYAALGFT 210 A++ED+ V + R +GVG L+ +A+E A+ L L + +A FYA F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 211 SHGVSLALHLG 221 V L+ Sbjct: 148 IGAVDTMLYSN 158
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 38.7 bits (90), Expect = 3e-05 Identities = 36/177 (20%), Positives = 61/177 (34%), Gaps = 21/177 (11%) Query: 31 LLQAHLSHRSALHSRFRFDPAAVMDCLRAEVLGQEPALQAVEDMLKVVRADIADPRRPLF 90 ++ L+ S+ D M ++G+ A+Q + +L + L Sbjct: 114 IIGRALAEPKRRPSKLEDDSQDGMP-----LVGRSAAMQEIYRVLARL----MQTDLTL- 163 Query: 91 SALFLGPTGVGKTEIVRALARALHGDAEGFCRVDMNTLSQEHYAAALTGAPPG-YVGA-K 148 + G +G GK + RAL F ++M + ++ + L G G + GA Sbjct: 164 --MITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQT 221 Query: 149 EGTTLLEQDKLDGSPGRPGIVLFDELEKASPEVVHALLNVLDNGLLRVASGERTYHF 205 T EQ +G G + DE+ + LL VL G G Sbjct: 222 RSTGRFEQ--AEG-----GTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRS 271
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 28.4 bits (63), Expect = 0.013 Identities = 18/93 (19%), Positives = 35/93 (37%), Gaps = 3/93 (3%) Query: 75 AADRVFVKHGY--LPTAELVDHLRALRAERVLVCGIQADTCVLAAGFALFDAGLQPTLIG 132 D V K Y L++ +R +++++ GI A L F ++ +G Sbjct: 116 DDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVG 175 Query: 133 DLVLGSSLDRSGELGVRLWKHHFGQVVSLAEVL 165 D V SL++ ++ + V +L Sbjct: 176 DAVADFSLEKH-QMALEYAAGRCAFTVMTDSLL 207
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.026 Identities = 16/100 (16%), Positives = 35/100 (35%), Gaps = 17/100 (17%) Query: 341 VDNLLRNAVRFNPVGQPLEVRASSAGDYLRLSVRDHGPGIAAELQEQLGEPFFRAPNQSS 400 V+N +++ + P G + ++ + + L V + G +E Sbjct: 264 VENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE-------------- 309 Query: 401 PGHGLGLA-IARRAIERHGGHLRLG-NHPDGGFIATLSLP 438 G GL + R +G ++ + G A + +P Sbjct: 310 -STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 103 bits (258), Expect = 9e-28 Identities = 42/117 (35%), Positives = 63/117 (53%) Query: 4 LLLIDDDRELCELLGTWLVQEGFSVRASHDGAQARRALAEQTPDAVVLDVMLPDGSGLEL 63 +L+ DDD + +L L + G+ VR + + A R +A D VV DV++PD + +L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 64 LKQLRGDHPDLPVLMLSARGEPLDRILGLELGADDYLAKPCDPRELTARLRAVLRRT 120 L +++ PDLPVL++SA+ + I E GA DYL KP D EL + L Sbjct: 66 LPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 28.1 bits (62), Expect = 0.010 Identities = 16/76 (21%), Positives = 31/76 (40%), Gaps = 8/76 (10%) Query: 22 EEPAPAPIPAAQPSITQATAELERRLVETERQRDELVSRMRQENRQLREQ--------LQ 73 E P P P PA T+ AE ++ +T + ++ + +NR++ ++ Q Sbjct: 1022 EAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQ 1081 Query: 74 AAQAQRQPPLLTEEQT 89 + + E QT Sbjct: 1082 TNEVAQSGSETKETQT 1097
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 30.4 bits (68), Expect = 9e-04 Identities = 13/45 (28%), Positives = 18/45 (40%) Query: 53 AAGFTGSLIVAEFDSLAAAQSWAEADPYRAAGVYAEVVVKPFKKV 97 G GS+ E ++ A W + +P A V A V KV Sbjct: 278 VIGGLGSVAGFEKNTREAVDRWIQENPNAAETVEAVFNVAAAAKV 322
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 90.9 bits (225), Expect = 4e-24 Identities = 56/195 (28%), Positives = 91/195 (46%), Gaps = 5/195 (2%) Query: 11 LKDRVILVTGAGRGIGAAAAKTFAAHGATVLLLGKTEEYLNEVYDAIEAAGHPQAAVIPF 70 ++ ++ +TGA +GIG A A+T A+ GA + + E L +V +++A A F Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA---F 62 Query: 71 NLETAQPHQFEELAATLENEFGRIDGLLHNASILGPRSPMQQISGENFMRVMQVNVNAMF 130 + +E+ A +E E G ID L++ A +L P + +S E + VN +F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRP-GLIHSLSDEEWEATFSVNSTGVF 121 Query: 131 MLTTAMLPLMKLSSDASIIFTSSSVGRKGRAYWGAYSVSKFATEGLMQTLADELDGTSAI 190 + ++ M SI+ S+ R AY+ SK A + L EL I Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE-YNI 180 Query: 191 RANSVNPGATRTSMR 205 R N V+PG+T T M+ Sbjct: 181 RCNIVSPGSTETDMQ 195
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 36.6 bits (85), Expect = 2e-04 Identities = 20/41 (48%), Positives = 23/41 (56%), Gaps = 3/41 (7%) Query: 341 DAHRALRMA---TLNGARALGLERLIGSLEAGKAADLVAFD 378 D R R T+N A A GL IGSLE GK ADLV ++ Sbjct: 398 DNFRVKRYIAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 118 bits (297), Expect = 1e-38 Identities = 35/89 (39%), Positives = 54/89 (60%), Gaps = 1/89 (1%) Query: 2 TKSELIERIVTHQGQLSAKDVELAIKTMLEQMSQALATGDRIEIRGFGSFSLHYRAPRVG 61 K +LI + V +L+ KD A+ + +S LA G+++++ GFG+F + RA R G Sbjct: 3 NKQDLIAK-VAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 62 RNPKTGESVRLDGKFVPHFKPGKELRDRV 90 RNP+TGE +++ VP FK GK L+D V Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 257 bits (659), Expect = 2e-86 Identities = 101/341 (29%), Positives = 159/341 (46%), Gaps = 30/341 (8%) Query: 19 LITGVAGFIGSNLLETLLKLDQKVVGLDNFATGHQRNLDEVRSLVSEKQWSNFKFIQGDI 78 L+TG AGFIG ++ + LL+ +VVG+DN + +L + R + + F+F + D+ Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQ--PGFQFHKIDL 61 Query: 79 RNLDDCNNACA--GVDYVLHQAALGSVPRSINDPITSNATNIDGFLNMLIAARDAKVQSF 136 + + + A + V +V S+ +P +N+ GFLN+L R K+Q Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 137 TYAASSSTYGDHPGLP-KVEDTIGKPLSPYAVTKYVNELYADVFSRCYGFSTIGLRYFNV 195 YA+SSS YG + +P +D++ P+S YA TK NEL A +S YG GLR+F V Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 196 FGRRQDPNGAYAAVIPKWTSSMIQGDDVYINGDGETSRDFCYIENTVQANLLAATAGLDA 255 +G P+ A K+T +M++G + + G+ RDF YI++ +A + A Sbjct: 182 YGPWGRPDMAL----FKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 256 RNQ----------------VYNIAVGGRTSLNQLFFALRDGLAENGVSYHREPVYRDFRE 299 Q VYNI L AL D L G+ + + Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDAL---GIEAKKN--MLPLQP 292 Query: 300 GDVRHSLADISKAAKLLGYAPKYDVSAGVALAMPWYIMFLK 340 GDV + AD +++G+ P+ V GV + WY F K Sbjct: 293 GDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDFYK 333
>PF07520#Virulence protein SrfB Length = 1041 Score = 28.8 bits (64), Expect = 0.042 Identities = 24/119 (20%), Positives = 46/119 (38%), Gaps = 10/119 (8%) Query: 40 MHMSEALVSAYPPARRLDRPLWLLRELLHRLPQVIGSYGSDVVILQRELLSTIPTLEFLT 99 + ++EA++SA A DR + ++L +P +G G + T L++L Sbjct: 696 VPLAEAILSACEDAEEADRIDIPVADVLGLVPTPVGEEGDEEGHEDASPQVTDEILDYLE 755 Query: 100 K--------APRILDVDDAIWLHRRGIAANSIARRVDHIVCG--NQYLADYFGQFGRPT 148 K R+ D+ + A + ++V +C + D GRP+ Sbjct: 756 KPATQLGAEGWRLADMVLSASREDLDAIAREVFQKVLGNMCEVIDHLGCDVVLLTGRPS 814
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 50.9 bits (122), Expect = 1e-09 Identities = 46/253 (18%), Positives = 92/253 (36%), Gaps = 48/253 (18%) Query: 14 KANVQGT---LDLAREAVSRGVRRFIFISSIKVNGEGTEPGRPY-TADSPPNPVDPYGVS 69 +N+ G L+ R ++ ++ SS V G + P+ T DS +PV Y + Sbjct: 100 DSNLTGFLNILEGCRHN---KIQHLLYASSSSVYGLNRKM--PFSTDDSVDHPVSLYAAT 154 Query: 70 KREAEQALLDLAEETGLEVVIIRPVLVYGPGVKAN--VQTMMRWLKRGVPLPL-GAIHNR 126 K+ E + GL +R VYGP + + + + + G + + + Sbjct: 155 KKANELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMK 214 Query: 127 RSLVSLDNLVDLIITCIEHPA-----------------AVGQVFLVSDGEDLSTTELLRR 169 R +D++ + II + A +V+ + + + + ++ Sbjct: 215 RDFTYIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQA 274 Query: 170 MGRALGAPAR--LLPVPASWIGAAAKVLNRQAFARRLCGSLQVDIMKTRQVLGWTPPVGV 227 + ALG A+ +LP+ V + A D +V+G+TP V Sbjct: 275 LEDALGIEAKKNMLPLQ------PGDV--LETSA---------DTKALYEVIGFTPETTV 317 Query: 228 DQALEKTARSFLD 240 ++ + D Sbjct: 318 KDGVKNFVNWYRD 330
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 33.3 bits (76), Expect = 0.003 Identities = 16/62 (25%), Positives = 26/62 (41%), Gaps = 2/62 (3%) Query: 575 KLQRELEALPGQIDAVEAELAGVQETIAQ--QDFYLRPQDEQRETLARLDALQQELDALL 632 + EL Q++ +E+E+ +E Q F D+ R+T + L EL Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNE 322 Query: 633 ER 634 ER Sbjct: 323 ER 324
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 27.4 bits (61), Expect = 0.019 Identities = 12/39 (30%), Positives = 18/39 (46%), Gaps = 2/39 (5%) Query: 17 DPVMKRAAALATSNQARLSVVHVV-EPMAMAFGGDVPMD 54 V +RA + A V ++ EPMA A G +P+ Sbjct: 119 TQVERRAIRESAQG-AGAREVFLIEEPMAAAIGAGLPVS 156
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.9 bits (168), Expect = 2e-16 Identities = 25/93 (26%), Positives = 40/93 (43%), Gaps = 1/93 (1%) Query: 4 SETVERILDAAEQLFAEKGFAETSLRLITSKAGVNLAAVNYHFGSKKALIQAVFSRFLGP 63 ET + ILD A +LF+++G + TSL I AGV A+ +HF K L ++ Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 64 FCASLEKELDRRQAKPEAQ-HATLEDLLHLLVS 95 + + P + L +L V+ Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVT 102
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 28.8 bits (64), Expect = 0.022 Identities = 29/128 (22%), Positives = 45/128 (35%), Gaps = 22/128 (17%) Query: 15 HPALALLRPLEALYRRVANGRRADFLSGRKPAYRAPLPVLVVGNITVGGTGKTPM----I 70 L P R R+A+ L+GR A A L + V + G + P+ + Sbjct: 26 REHDLLWLPHHDRLRSAGRKRKAEHLAGRIAAVHA-LREVGVRTVPGMGDKRQPLWPDGL 84 Query: 71 LWMIEHCRARGLRVGVISRGYGARPPTTPWRVRAEQDAAEAGDEPLMIVRRSGVPLMIDP 130 I HC L V + + G + E+ ++ L P +ID Sbjct: 85 FGSISHCATTALAV-ISRQRIG---------IDIEKIMSQHTATEL-------APSIIDS 127 Query: 131 DRPRALQA 138 D + LQA Sbjct: 128 DERQILQA 135
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 57.8 bits (139), Expect = 2e-10 Identities = 54/316 (17%), Positives = 94/316 (29%), Gaps = 41/316 (12%) Query: 760 RRSRGQRRRSNRRERQREVSGELEGSEATDNA-----AAPLNTVAAAAAAGIAVA--SEA 812 R G+ N +R + + +N + P N A V + A Sbjct: 972 RNVNGRYDLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPA 1031 Query: 813 VEANVEQAPATTSEAAGETTASDETDASTSEAVETQGA-----DSEANT---------GE 858 + + A S+ +T +E DA+ + A + A + +ANT E Sbjct: 1032 TPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSE 1091 Query: 859 TADIEAPVTVSVVRDEAGQSTLLVAQATEEAPFASESVESREDAESAVQPATEAAEEVAA 918 T + + T E + + + T+E P + V +++ VQP E A E Sbjct: 1092 TKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARE--- 1148 Query: 919 PVPVEAAAPSEPATTEEPTPAIAAVPANATGRALNDPREKRRLQREAERLAR--EAAAAA 976 P + ++ T A PA T + P + + E A Sbjct: 1149 NDPTVNI---KEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPA 1205 Query: 977 EAAAQAAPAVEEVPAVASEEA----SAQEEPAA---PQAEEIAQADVPSQ-----ADEAQ 1024 P + EPA +A D+ S +A+ Sbjct: 1206 TTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDAR 1265 Query: 1025 EAVQAEPEASGEDATD 1040 Q G+ + Sbjct: 1266 AKAQFVALNVGKAVSQ 1281 Score = 53.9 bits (129), Expect = 3e-09 Identities = 50/349 (14%), Positives = 102/349 (29%), Gaps = 36/349 (10%) Query: 508 EAQPVSSTRTLVRQEAAVKTVAPQQPAPQHTEAPVEPAKPMPEPSLFQGLVKSLVGLFAG 567 + +++ + +V + + EAPV P P PS V A Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEEIARVD--EAPVPPPAP-ATPSETTETV-------AE 1042 Query: 568 KDQPAAKPAETSKPAAERQTRQDERRNGRQQNRRRDGRDGNRRDEERKPREERAERQPRE 627 + +K E ++ A T Q+ ++ + N + +E + +E Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 628 ERAERPNREERSERRREERAERPAREERQPREGREERAERTPREERQPREGREGREERSE 687 + + E + + + + P++ + E + R+ +E +S+ Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQV-SPKQEQSETVQPQAEPARENDPTVNIKEPQSQ 1161 Query: 688 RRREERAERPAREERQPREGREERAERPAREERQPREDRQARDAAALEAEALPNDESLEQ 747 E+PA+E E + +E Sbjct: 1162 TNTTADTEQPAKETS--------SNVEQPVTESTTVN---------------TGNSVVEN 1198 Query: 748 DEQDDTDGERPRRRSRGQRRRSNRRERQ-REVSGELEGSEATDNAAAPLNTVAAAAAAGI 806 E +P S + NR R R V +E + + N + + + Sbjct: 1199 PENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTN 1258 Query: 807 AVASEAVEANVEQAPATTSEAAGETTASDETDASTSEAVETQGADSEAN 855 AV S+A A + +A + + E + V N Sbjct: 1259 AVLSDAR-AKAQFVALNVGKAVSQHISQLEMNNEGQYNVWVSNTSMNKN 1306 Score = 53.5 bits (128), Expect = 4e-09 Identities = 36/187 (19%), Positives = 60/187 (32%), Gaps = 27/187 (14%) Query: 896 VESREDAESAVQPATEAAEEVAAP-VPVEAAAPSEPATTEEPTPAIAAVPANATGRALND 954 VE R T + P VP + P PA A A N Sbjct: 985 VEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENS 1044 Query: 955 PREKRRLQR------EAERLAREAAAAAEAAAQAAPAVEEVPAVASEEASAQ----EEPA 1004 +E + +++ E RE A A++ +A EV SE Q +E A Sbjct: 1045 KQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETA 1104 Query: 1005 APQAEEIAQADVPSQADEAQEA--------------VQAEPEASGEDATDTEH--AKKTE 1048 + EE A+ + + + QAEP + + + ++ Sbjct: 1105 TVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNT 1164 Query: 1049 ESETSRP 1055 ++T +P Sbjct: 1165 TADTEQP 1171 Score = 48.5 bits (115), Expect = 2e-07 Identities = 53/338 (15%), Positives = 94/338 (27%), Gaps = 62/338 (18%) Query: 616 PREERAERQPREERAERPNREERSERRREERAERPAREERQPREGREERAERTPREERQP 675 P E+ + PN + E AR + P A TP E + Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVP---PPAPATPSETTET 1039 Query: 676 REGREGREERSERRREERAERPAREERQPREGREERAERPAREERQPREDRQARDAAALE 735 +E ++ + E+ A + R+ + E ++ A + Q + A Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAK--EAKSNVKA--------NTQTNEVAQSG 1089 Query: 736 AEALPNDESLEQDEQDDTDGERPRRRSRGQRRRSNRRERQREVSGELEGSEATDNAAAPL 795 +E E+ + ++ E+ + + + +VS + E SE A P Sbjct: 1090 SET---KETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPA 1146 Query: 796 NTVAAAAAAGIAVASEAVEANVEQAPATTSEAAGETTASDETDASTSEAVETQGADSEAN 855 + A+ EQ TS + T + + VE + A Sbjct: 1147 RENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206 Query: 856 TGETADIEAPVTVSVVRDEAGQSTLLVAQATEEAPFASESVESREDAESAVQPATEAAEE 915 T T + E+ S ++R P Sbjct: 1207 TQPTVNSES----------------------------SNKPKNRHRRSVRSVPHNV---- 1234 Query: 916 VAAPVPVEAAAPSEPATTEEPTPAIAAVPANATGRALN 953 EPATT + A+ + T N Sbjct: 1235 -------------EPATTSSNDRSTVAL-CDLTSTNTN 1258 Score = 43.9 bits (103), Expect = 3e-06 Identities = 47/237 (19%), Positives = 74/237 (31%), Gaps = 25/237 (10%) Query: 427 EALKDRTAEVRARVPFQVAAFLLNEKRNAITKIELRTRARIFILPDDHLETPHFEVQRLR 486 A T E A Q + + +++A + T EV + Sbjct: 1030 PATPSETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSG 1089 Query: 487 DDSPELVAGQTSYEMATVEHEEAQPVSSTRTLVRQEAAVKT--VAPQQPAPQHTEAPVEP 544 ++ E +T E ATVE EE V + +T QE T V+P+Q + + EP Sbjct: 1090 SETKETQTTETK-ETATVEKEEKAKVETEKT---QEVPKVTSQVSPKQEQSETVQPQAEP 1145 Query: 545 AKPMPEPSLFQGLVKSLVGLFAGKDQPAAKPAETSKPAAERQTRQDERRNGRQQNRRRDG 604 A +P+ K+ ++T+ A Q ++ N Q Sbjct: 1146 A-RENDPT------------VNIKE----PQSQTNTTADTEQPAKETSSNVEQPVTESTT 1188 Query: 605 RDGNRRDEERKPREERAERQP--REERAERPNREERSERRREERAERPAREERQPRE 659 + E A QP E + +P R R PA R Sbjct: 1189 VNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 27.8 bits (62), Expect = 0.045 Identities = 22/85 (25%), Positives = 39/85 (45%), Gaps = 7/85 (8%) Query: 19 VKADNSGVDLANVKM---SMNPFCEIAVEEAVRLKEKGVATEIVAVSVGPTAAQEQLRTA 75 VKA+ G + + + + F + +EEA+ L+E+G I+ + G AQ+ Sbjct: 34 VKANAYGHGIERIWSAIGATDGFALLNLEEAITLRERGWKGPIL-MLEGFFHAQD---LE 89 Query: 76 LALGADRAILVESNDELNSLAVAKL 100 + V SN +L +L A+L Sbjct: 90 IYDQHRLTTCVHSNWQLKALQNARL 114
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.034 Identities = 6/16 (37%), Positives = 8/16 (50%) Query: 258 FRRAYGMTPAAYRRQC 273 +R AYG + RQ Sbjct: 672 YRGAYGRYVQDHPRQV 687
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 27.1 bits (60), Expect = 0.049 Identities = 9/53 (16%), Positives = 18/53 (33%), Gaps = 8/53 (15%) Query: 74 ADHLSAAIFLQRELGGCLAIGARITQVQAKFSGLFNLGEAFPVDGRQFEHLFE 126 L+ A+ G L + + SGL++ ++ P + L Sbjct: 66 QCLLAGALNPLLNAGPGLGLDEK--------SGLYHAYQSIPREKLSVPTLKR 110
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 39.9 bits (93), Expect = 7e-06 Identities = 49/266 (18%), Positives = 96/266 (36%), Gaps = 43/266 (16%) Query: 43 PSRAVSHDINLTEMMVALGLQTRMVGYTGISGW--WKNADPGLIAALKPLPELV-----A 95 P+R V+ + E+++ALG+ G + W + +P PLP+ V Sbjct: 35 PNRIVALEWLPVELLLALGIVP--YGVADTINYRLWVS-EP-------PLPDSVIDVGLR 84 Query: 96 RYPTAETLLDVDADFFFAGWGYGMRVGGDLTPASLEPLG-VKVYELSESCAQIGEPRRAS 154 P E L ++ F GYG +P L + + + S+ + R++ Sbjct: 85 TEPNLELLTEMKPSFMVWSAGYGP------SPEMLARIAPGRGFNFSDGKQPLAMARKS- 137 Query: 155 LDELYRDLRNLGRIFDVEPRAERLVASLQARIERARAGIPANTEAPRVF--LYDSGEDRP 212 L + + +++ AE +A + I + P + L D Sbjct: 138 -------LTEMADLLNLQSAAETHLAQYEDFIRSMKPRFVKRGARPLLLTTLIDPRHMLV 190 Query: 213 FTSGRLGMPQALIEAAGGRSVTDDVAASW--TQVNWESVVA-RDPQVIVIVDYGETSAAQ 269 F + Q +++ G + W T V+ + + A +D V+ D+ + Sbjct: 191 FGPN--SLFQEILDEYGIPNAWQGETNFWGSTAVSIDRLAAYKDVDVLCF-DHDNSKDMD 247 Query: 270 KQRFLEENPALRSLTAIRERRFIVLP 295 L P +++ +R RF +P Sbjct: 248 A---LMATPLWQAMPFVRAGRFQRVP 270
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 70.0 bits (171), Expect = 4e-17 Identities = 32/190 (16%), Positives = 65/190 (34%), Gaps = 8/190 (4%) Query: 14 ESARGKLLQTAAHLFRSKGYERTTVRDLASAVGIQSGSIFHHFKSKDEILRSVMEETILY 73 + R +L A LF +G T++ ++A A G+ G+I+ HFK K ++ + E + Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 74 NTALMRAALAD-AEDLRERVLGLIRCELQSIMGGTGEAMAVLVYEWRSLSAEGQAYILGL 132 L A D + ++ L+S + + + + + A + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 133 RDIYEQMWLD----VLGEARLAGYCQG--DPFILRRFLTGALSWT-TTWFRPEGPMSLDQ 185 + D L A + G +S W L + Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKK 189 Query: 186 LAEEALALVI 195 A + +A+++ Sbjct: 190 EARDYVAILL 199
>PF06580#Sensor histidine kinase Length = 349 Score = 45.2 bits (107), Expect = 2e-07 Identities = 35/172 (20%), Positives = 72/172 (41%), Gaps = 24/172 (13%) Query: 198 QIGELVSGLKDFAR--LDRAFSEEVDLND---CVRNAVLIARTAIKDKAEISSQLGELPL 252 + E+++ L + R L + + +V L D V + + +A +D+ + +Q+ + Sbjct: 192 KAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIM 251 Query: 253 IACAPSQINQVLL-NLLTNAAQAMERFGRILLKSWADERQVFLSVQDNGKGMPAEVLGRI 311 P + Q L+ N + + + + G+ILLK D V L V++ G Sbjct: 252 DVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA-------- 303 Query: 312 FDPFFTTKPVGQGTGLGLSISYKIIQQHGG---TIRVASEPGRGTRFLISLP 360 K + TG GL + +Q G I+++ + G+ ++ +P Sbjct: 304 ------LKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVN-AMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 97.6 bits (243), Expect = 5e-25 Identities = 29/136 (21%), Positives = 57/136 (41%), Gaps = 2/136 (1%) Query: 7 RILFVDDEERILRSLAMQF-RRHYEVLTESDPRRALERLKTERIQVLVSDQRMPQMSGAE 65 IL DD+ I L R Y+V S+ + ++V+D MP + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 66 LLAQARERYPETLRILLTGYSDLDAAVDALNDGGIFRYLTKPWNPQEMAFTLRQAAEIAS 125 LL + ++ P+ ++++ + A+ A + G + YL KP++ E+ + +A Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKAS-EKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 126 RQGLPAPPAATLAAPL 141 R+ + PL Sbjct: 124 RRPSKLEDDSQDGMPL 139 Score = 54.8 bits (132), Expect = 1e-10 Identities = 27/139 (19%), Positives = 55/139 (39%), Gaps = 5/139 (3%) Query: 142 SVLLLDDDPETLDCVGAFCHAGGHRLLRARNLAEALVWLNTEPVEVLVSDLKLAGEHTAP 201 ++L+ DDD + G+ + N A W+ +++V+D+ + E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 202 LLKSLAQAHPRLLSLVVTPFRDTQALLELINQAQIFRYLPKPIRRGLFEKGLKAAAEQAL 261 LL + +A P L LV++ ++ + + YLPKP L +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKAS-EKGAYDYLPKP----FDLTELIGIIGRAL 119 Query: 262 LWRGRSLPEVDRLAEVPRD 280 R +++ ++ Sbjct: 120 AEPKRRPSKLEDDSQDGMP 138
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.003 Identities = 12/43 (27%), Positives = 21/43 (48%) Query: 103 DEINRATPKSQSALLEAMEEGQVTIEGATRPLPEPFFVIATQN 145 DEI +Q+ LL +++G+ T G P+ ++A N Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATN 280
>VACJLIPOPROT#VacJ lipoprotein signature. Length = 251 Score = 272 bits (698), Expect = 3e-95 Identities = 75/231 (32%), Positives = 113/231 (48%), Gaps = 15/231 (6%) Query: 16 LACASLALAPTLSLAAS--------EEDPWESINRPIFTFN-DTLDTYALKPLAQGYQKV 66 L ++LAL TL + + DP E NR ++ FN + LD Y ++P+A ++ Sbjct: 3 LRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNFNVLDPYIVRPVAVAWRDY 62 Query: 67 TPNFVQDGVHNFFNNLGDVKNLANNLLQAKFHNAGVDTSRLLFNSTFGLAGLIDVATPMG 126 P ++G+ NF NL + + N LQ + V +R N+ G+ G IDVA Sbjct: 63 VPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTRFFLNTILGMGGFIDVAGMAN 122 Query: 127 LQ---RNDEDFGQTLGYWGVGSGPYVMLPFLGPSTLRDAPAKIPDIYVSPYHYMDDVRAR 183 + FG TLG++GVG GPYV LPF G TLRD + D ++ + Sbjct: 123 PKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRDDGGDMADALYPVLSWLTWPMSV 182 Query: 184 NVMFGINTVDTRANLLKSEKLI--SGDKYIFIRNAYLQNREFKVKDGEVED 232 + + ++TRA LL S+ L+ S D YI +R AY Q +F GE++ Sbjct: 183 G-KWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYFQRHDFIANGGELKP 232
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 110 bits (277), Expect = 7e-29 Identities = 39/128 (30%), Positives = 60/128 (46%), Gaps = 1/128 (0%) Query: 6 ATLLIIDDDEVVRESLAAYLEDSNFKVLQALNGLQGLQIFESEQPDLVICDLRMPQIDGL 65 AT+L+ DDD +R L L + + V N + + DLV+ D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 66 ELIRRIRQTASETPIIVLSGAGVMSDAVEALRLGAADYLIKPLEDLAVLEHSVRRALDRA 125 +L+ RI++ + P++V+S A++A GA DYL KP DL L + RAL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPF-DLTELIGIIGRALAEP 122 Query: 126 YLRVENQR 133 R Sbjct: 123 KRRPSKLE 130
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 42.7 bits (100), Expect = 5e-08 Identities = 27/105 (25%), Positives = 40/105 (38%) Query: 2 AITAALQPIESEPVITKSRVGAFTGTELDELLWAHDIETLLIAGATTSGVVLTTVRQAFD 61 I L P + + V+TK R AF T L E++ + L+I G L T +AF Sbjct: 107 KIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFM 166 Query: 62 LDYQLVVLRDGCVDGDAELHDYLMARVISDHATITEIDEVAKTLR 106 D + + D D E H + A D + L+ Sbjct: 167 EDIKAFFVGDAVADFSLEKHQMALEYAAGRCAFTVMTDSLLDQLQ 211
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 103 bits (259), Expect = 1e-26 Identities = 85/362 (23%), Positives = 148/362 (40%), Gaps = 13/362 (3%) Query: 15 RNLAVCLFGAFTTVFAMTLILPFLPVYIGQLGVSGHAAIVQWSGIAYAATFVTAGLVAPL 74 R L V L + LI+P LP + L S GI A + AP+ Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVT--AHYGILLALYALMQFACAPV 62 Query: 75 WGMLGDRYGRKPMLVRASLGMAITMLLMGLASDIWQFIGLRLLAGIAGGYSSGATILVAV 134 G L DR+GR+P+L+ + G A+ +M A +W R++AGI G + A +A Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIAD 122 Query: 135 QAPKSRSAWALGLLSSGVMAGNLLGPLVGGFLPPLIGIRATFWGASGLIFIAFVFTTFML 194 A G +S+ G + GP++GG + A F+ A+ L + F+ F+L Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGCFLL 181 Query: 195 RETA---RPSVPAVEEPPKVGWSNMPNKAVILAMLATGLLLMIANMSVEPIITVYIETLL 251 E+ R + P + V+ A++A ++ + + ++ E Sbjct: 182 PESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRF 241 Query: 252 EDSRRVTSVAGLAMSA-AALGSIISATYLGKVADRIGYGVIMIAALSVAAVLLIPQAFVY 310 + G++++A L S+ A G VA R+G ++ + I AF Sbjct: 242 HWD---ATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 311 AGWQLIALRFLMGMALGGL-LPCMAAVIRHSVPERFVGSAMGWSLSAQFAGQVIGPVIGG 369 GW + L +A GG+ +P + A++ V E G G + ++GP++ Sbjct: 299 RGWMAFPIMVL--LASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356 Query: 370 FV 371 + Sbjct: 357 AI 358 Score = 51.4 bits (123), Expect = 3e-09 Identities = 43/177 (24%), Positives = 73/177 (41%), Gaps = 4/177 (2%) Query: 217 PNKAVILAMLATGLLLMIANMSVEPIITVYIETLLEDSRRVTSVAGLAMSAAALGSIISA 276 PN+ +I+ + L + + + P++ + L+ S VT+ G+ ++ AL A Sbjct: 3 PNRPLIVILSTVALDAVGIGL-IMPVLPGLLRDLVH-SNDVTAHYGILLALYALMQFACA 60 Query: 277 TYLGKVADRIGYGVIMIAALSVAAVLLIPQAFVYAGWQLIALRFLMGMALGGLLPCMAAV 336 LG ++DR G +++ +L+ AAV A W L R + G+ G A Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAY 119 Query: 337 IRHSVPERFVGSAMGWSLSAQFAGQVIGPVIGGFVGGQFGIRSVFLVTSLLMLAGAL 393 I G+ + G V GPV+GG + G F + F + L L Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNFL 175
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 45.4 bits (107), Expect = 3e-08 Identities = 25/73 (34%), Positives = 36/73 (49%) Query: 1 MRYKPEQKQATRALLLSKAAPLVKRQGFASTGLDTLMKAAGLTTGAFYSQFSSKAELLEA 60 R ++ Q TR +L A L +QG +ST L + KAAG+T GA Y F K++L Sbjct: 2 ARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSE 61 Query: 61 ILQRELSAQHDAF 73 I + S + Sbjct: 62 IWELSESNIGELE 74
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 27.9 bits (62), Expect = 0.045 Identities = 14/48 (29%), Positives = 22/48 (45%), Gaps = 8/48 (16%) Query: 18 IPVVG----RYLFFSISQPEQVAATLASLAA---ATDGYQLVVGIGHS 58 PVVG +Y ++ P+ V ++ A G Q V+ IG+S Sbjct: 79 WPVVGWSSLKY-YWKQKDPKDVTQDTLAIIDKYQAEFGTQKVILIGYS 125
>MICOLLPTASE#Microbial collagenase metalloprotease (M9) signature. Length = 1104 Score = 27.8 bits (61), Expect = 0.012 Identities = 12/24 (50%), Positives = 15/24 (62%) Query: 33 NLNAYASADGSKLMGTWICTPGKW 56 N YA+ADG+KL T PGK+ Sbjct: 1059 NYVDYANADGNKLSNTCKLNPGKY 1082
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 29.1 bits (65), Expect = 0.028 Identities = 12/35 (34%), Positives = 16/35 (45%) Query: 104 DSGRLFGALRTLSERYPLLDVEVLSAAQDDALALL 138 L AL +S+ PLL V SA + L+ L Sbjct: 357 QREMLLDALLEISDSDPLLRYYVDSATHEIILSFL 391
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 114 bits (286), Expect = 7e-37 Identities = 34/89 (38%), Positives = 55/89 (61%) Query: 5 TKAEIAERLYEELGLNKREAKELVELFFEEIRQALEQNEQVKLSGFGNFDLRDKRQRPGR 64 K ++ ++ E L K+++ V+ F + L + E+V+L GFGNF++R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 65 NPKTGEEIPITARRVVTFRPGQKLKARVE 93 NP+TGEEI I A +V F+ G+ LK V+ Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAVK 91
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.035 Identities = 40/257 (15%), Positives = 77/257 (29%), Gaps = 39/257 (15%) Query: 225 DQPARQALAPALLRGLGGAGVAEEALQQAAATFVENTEGLLLLDL-----NAIVQLARVE 279 D A + + L G L++ D+ NA L R++ Sbjct: 11 DDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDLLPRIK 70 Query: 280 GLAMER----------IADAVRRYKVGVTE---DPWLKID-RQRIRQADEIVRRRVKGQQ 325 + A++ + G + P+ + I +A +RR + Sbjct: 71 KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKRRPSKLE 130 Query: 326 HAVTHMLDIVKR--AMTGV--GASRKGNRPRGVAFLAGPTGVGKTELAKTVTSLLFGDES 381 + +V R AM + +R + + G +G GK +A+ + Sbjct: 131 DDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTL-MITGESGTGKELVARALHDYGKRRNG 189 Query: 382 AYIRFDMSEFSAEHADQRLIGAPPGYVGYDVGGELTNAIREKP--FS-----VVLFDEIE 434 ++ +M+ + + L G G T A F + DEI Sbjct: 190 PFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRSTGRFEQAEGGTLFLDEIG 241 Query: 435 KAHPRILDKFLQILDDG 451 + L++L G Sbjct: 242 DMPMDAQTRLLRVLQQG 258
>PF07328#T-DNA border endonuclease VirD1 Length = 144 Score = 28.1 bits (62), Expect = 0.027 Identities = 20/75 (26%), Positives = 32/75 (42%), Gaps = 13/75 (17%) Query: 264 MLRIRFDEARSAAAGAALEDLDETLATAIRQFQFRDIRPKAASEIADLGRASRLLGHTDK 323 M+R R+ EA AAG A +D+ ++ + + +E+A+ LG Sbjct: 1 MIRGRWREAEDGAAGPA--RVDKVISVKMTE-----------AELAEFDAQIAELGLNRN 47 Query: 324 RITETVYRRVGEIVE 338 R RR+G VE Sbjct: 48 RALRIAARRIGGFVE 62
>PF05272#Virulence-associated E family protein Length = 892 Score = 54.3 bits (130), Expect = 1e-09 Identities = 40/114 (35%), Positives = 57/114 (50%), Gaps = 7/114 (6%) Query: 4 SQIAQRLADRVIDVAHHLLPGGKREGSEWRVGSVNGEKGQSLGVHLKGEKAGVWCDFSTG 63 + +A L R D+ LPGG G E+ GS+ G KG S V++ G WCDFSTG Sbjct: 12 TSLADALLTRAKDLLPEWLPGGVLVGHEYECGSLAGGKGDSCKVNVT---TGKWCDFSTG 68 Query: 64 ETG-DLLDLWRAVRSCDMGTALTEAKSYLG---IAEPKLEAPSRKAYVRPDRPK 113 E+G DLLDL+ + + A + G +A + AP+ +P RP+ Sbjct: 69 ESGRDLLDLYAEIHGLKVSKAAAQVAREEGLESVAGIVMGAPAGAPAPKPPRPE 122
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.046 Identities = 25/180 (13%), Positives = 58/180 (32%), Gaps = 21/180 (11%) Query: 330 TVSSLRQFATEANGVAREAMANIDQTLSRPLAGQAFKQFYADAQKAAEDSAQATIDAREE 389 + F + + I + S + K+ D ++A + A I+ E Sbjct: 169 KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYEN 228 Query: 390 VKKTGDAFVEESSKSQKAIKQTV--DAIDSQIRALQLQAEMVGMSTREQTLFKLALDGAT 447 + KS+ ++ ++ L+ + + V L Sbjct: 229 LS--------RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYV---EAVNEL------RVY 271 Query: 448 QSQLDQAEAALNAVDAFDKVKKQQEDYKSLVADLRTEEEQLTDQMRERLAVLDAMQGLSD 507 +SQL+Q E+ + + + + + +K+ + D + + LA + Q S Sbjct: 272 KSQLEQIESEILSAKE--EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASV 329
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 31.3 bits (70), Expect = 7e-04 Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 61 AEQVRQVAALRQADEQRARDAAQALEQGRQQAAERYAA 98 A+ + AA +A EQ A +A + E+ +Q A AA Sbjct: 210 AKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAA 247 Score = 26.3 bits (57), Expect = 0.047 Identities = 15/59 (25%), Positives = 24/59 (40%), Gaps = 7/59 (11%) Query: 39 LDAALADLVACRAARGELESAVAEQVRQVAALRQADEQRARDAAQALEQGRQQAAERYA 97 L + L A +A+ + A + A R+A+EQ +Q +AA YA Sbjct: 200 LQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQAR-------QQAAIRAANTYA 251
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 636 bits (1641), Expect = 0.0 Identities = 245/1054 (23%), Positives = 434/1054 (41%), Gaps = 55/1054 (5%) Query: 9 SLRNRLLVIIGALVLMAYGAFTLTRTPVDVFPDLNKPTVTLMTEAGGMAAEEVEQLITFP 68 +R + + A++LM GA + + PV +P + P V++ G A+ V+ +T Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 69 LETAMNGLPSVESVRSVS-SAGLSFIYVTFDWKTDIFRARQMVSERLTSMEEGLAPGVTP 127 +E MNG+ ++ + S S SAG I +TF TD A+ V +L L V Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 128 TMGPIS-SVMGEIMQIAIPIGAKPSGQKNAAPPLSAMDTREYADWVLRPRLMAIPGVAQV 186 + S +M + P + D +Y ++ L + GV V Sbjct: 125 QGISVEKSSSSYLMVAGF---------VSDNPGTTQDDISDYVASNVKDTLSRLNGVGDV 175 Query: 187 IPIGGEVRQFQVQPNTTRMSELGVTASDLDAALKGFSANTSGGFL------EINGREYLI 240 G + ++ + +++ +T D+ LK + + G L I Sbjct: 176 QLFGAQ-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASI 234 Query: 241 RNLGRTSRLDDLRNLPLAVRA-GQPILLHQVADVQFAPAIKRGDAGFEGLPAVILGIQKQ 299 R ++ + L V + G + L VA V+ A G PA LGI+ Sbjct: 235 IAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLA 294 Query: 300 PTADTIALTRSIESALADMKGSLPAGMAEPQVTFRQANFIEASISTLQGKLIGASVFVAV 359 A+ + ++I++ LA+++ P GM + + F++ SI + L A + V + Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGM-KVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 360 ILFFFLGTLRPLVIALTAIPASIFVTGLVFHYFGLSINTMTLGGLAIAIGGLVDDAVVDV 419 +++ FL +R +I A+P + T + FG SINT+T+ G+ +AIG LVDDA+V V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 420 ENIMRRLKEDRTRHPENRLTPLVIVARASMEVRSAILYATMIIVLVFLPLFALPGMEGRL 479 EN+ R + E++L P ++ +++ A++ M++ VF+P+ G G + Sbjct: 414 ENVERVMM-------EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAI 466 Query: 480 FVPLGIAFIVSTLASLLVSVTVTPVLSYYLLPKMRTLDHGDT---------RLLAWLKTR 530 + I + + S+LV++ +TP L LL K + +H + Sbjct: 467 YRQFSITIVSAMALSVLVALILTPALCATLL-KPVSAEHHENKGGFFGWFNTTFDHSVNH 525 Query: 531 YQGGLQRVLQRPRAALGMAAVAVTLAVAAVPFFPTTFLPPFNEGTLLVGLRLNPGVTLAE 590 Y + ++L L + A+ V V P++FLP ++G L ++L G T Sbjct: 526 YTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQER 585 Query: 591 SSALAQQAE--LLVAQVPEVQHVGRRSGRAELDEHAEGVHVSELDVGLLPASELKR---S 645 + + Q L + V+ V +G + + + V L P E S Sbjct: 586 TQKVLDQVTDYYLKNEKANVESVFTVNGFSFSG---QAQNAGMAFVSLKPWEERNGDENS 642 Query: 646 MEEITADIRSRLAHLPGSIGIGQPISHRIDHMLSGVRSQIA-IKVFGEDLDVLRGQADLL 704 E + + L + I + I + + I G D L + L Sbjct: 643 AEAVIHRAKMELGKIRDGFVIPFNMP-AIVELGTATGFDFELIDQAGLGHDALTQARNQL 701 Query: 705 RAKLAGIPG-LADLEIEKQVLAPQIKIRVDYAAAGRYGVAAPQILSTLQSLVEGEKITEV 763 A P L + Q K+ VD A GV+ I T+ + + G + + Sbjct: 702 LGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDF 761 Query: 764 IEGNRRFALVVRLPEQAR-SIEGLSRILIDTPMGR-VPLSRLATIEDSDGPNQVSRDDGR 821 I+ R L V+ + R E + ++ + + G VP S T G ++ R +G Sbjct: 762 IDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGL 821 Query: 822 RRIVLSANAQ-GRPLSEVVADIRSVVQEVRLPEGYFITLGGQFQAQEEASRLVGLLSIVS 880 + + A G + +A + ++ + LP G G + + L +S Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAIS 879 Query: 881 LTLMFVVLYTRYKSVVLSALIMVNIPLALVGAVLGLWLSGQPLSVAALVGFITLAGISVR 940 ++F+ L Y+S + +M+ +PL +VG +L L Q V +VG +T G+S + Sbjct: 880 FVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAK 939 Query: 941 NGILKVSHYLNLMRMEGEDFDQKMIVRGSLERLSPVLMTALVTAFALAPLLFEASRPGTE 1000 N IL V +LM EG+ + + RL P+LMT+L + PL ++ G+ Sbjct: 940 NAILIVEFAKDLMEKEGKGV-VEATLMAVRMRLRPILMTSLAFILGVLPLAI-SNGAGSG 997 Query: 1001 ILHPVAVVIFSGLVSSTLLDTFLTPAMFWLFGRK 1034 + V + + G+VS+TLL F P F + R Sbjct: 998 AQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 67.9 bits (166), Expect = 1e-13 Identities = 55/358 (15%), Positives = 144/358 (40%), Gaps = 21/358 (5%) Query: 695 DVLRGQADLLRAKLAGIPGLADLEI---EKQVLAPQIKIRVDYAAAGRYGVAAPQILSTL 751 D+ A ++ L+ + G+ D+++ + + +I +D +Y + +++ L Sbjct: 153 DISDYVASNVKDTLSRLNGVGDVQLFGAQYAM-----RIWLDADLLNKYKLTPVDVINQL 207 Query: 752 QS----LVEGEKITEVIEGNRRFALVVRLPEQARSIEGLSRILI--DTPMGRVPLSRLAT 805 + + G+ ++ + + ++ E ++ + ++ V L +A Sbjct: 208 KVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVAR 267 Query: 806 IED-SDGPNQVSRDDGRRRIVLSAN-AQGRPLSEVVADIRSVVQEVR--LPEG-YFITLG 860 +E + N ++R +G+ L A G + I++ + E++ P+G + Sbjct: 268 VELGGENYNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPY 327 Query: 861 GQFQAQEEASRLVGLLSIVSLTLMFVVLYTRYKSVVLSALIMVNIPLALVGAVLGLWLSG 920 + + V ++ L+F+V+Y +++ + + + +P+ L+G L G Sbjct: 328 DTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFG 387 Query: 921 QPLSVAALVGFITLAGISVRNGILKVSHYLNLMRMEGEDFDQKMIVRGSLERLSPVLMTA 980 ++ + G + G+ V + I+ V + +M + ++ + + ++ A Sbjct: 388 YSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPP-KEATEKSMSQIQGALVGIA 446 Query: 981 LVTAFALAPLLFEASRPGTEILHPVAVVIFSGLVSSTLLDTFLTPAMFWLFGRKPAER 1038 +V + P+ F G I ++ I S + S L+ LTPA+ + + Sbjct: 447 MVLSAVFIPMAFFGGSTG-AIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 28.3 bits (63), Expect = 0.041 Identities = 20/79 (25%), Positives = 30/79 (37%), Gaps = 5/79 (6%) Query: 40 GQSVRKGQVLAYIEP-----ASGVLERSGQMAQVAELRAGQALAQKRLARLRELSETVPR 94 G+SVRKG VL + + + S A++ + R L +L EL Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 95 KEIEAAESEVNSLTERARA 113 +E EV LT + Sbjct: 175 YFQNVSEEEVLRLTSLIKE 193
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 55.2 bits (133), Expect = 2e-10 Identities = 67/315 (21%), Positives = 115/315 (36%), Gaps = 9/315 (2%) Query: 6 KNRTYRHLFTAQVIALVGTGL-MTVALGLLAYELAGADAGAVLGSALAIKMLAYVGVAPV 64 NR + + + VG GL M V GLL + D A G LA+ L APV Sbjct: 3 PNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPV 62 Query: 65 AQAFADQFPRRSLLVALDLVRAVVAICLPFVTEVWQIYLLIFVLQAASAGFTPTFQATIP 124 A +D+F RR +L+ AV + +W +Y+ ++ + A I Sbjct: 63 LGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG-RIVAGITGATGAVAGAYIA 121 Query: 125 DILPDEEDYTKALSLSRLAYDLESLISPMLAAALLTVISFHNLFAGTVLGFLVSAALVVS 184 DI ++ + + + P+L + FA L L L Sbjct: 122 DITD-GDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGL--NFLTGC 178 Query: 185 VRLPTTIPGPRRGIWDR---TTRGTRIYLATPRLRGLLAISLAVSAAGAMVIVNTVVLVK 241 LP + G RR + R + L+A+ + G + V+ + Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 242 ARFGLGEVEVASALAAFGG-GSMVAAFVLPSLLEKVADRTAMLTGATVLVVGTGIGALLP 300 RF + +LAAFG S+ A + + ++ +R A++ G G + A Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFAT 298 Query: 301 SYALLLPLWLIIGFG 315 + P+ +++ G Sbjct: 299 RGWMAFPIMVLLASG 313
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 46.4 bits (110), Expect = 2e-08 Identities = 19/115 (16%), Positives = 40/115 (34%), Gaps = 7/115 (6%) Query: 70 KTVELRSRVGGAVDAVSVPEGSLVRKGQLLFQIDPRPFQVALDTAVAQLRQAEVLASQAQ 129 ++ E++ V + V EG VRKG +L ++ + + L QA + ++ Q Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 130 ADFDRAER-------LVATGAVARKTYDDAASARNARQAQVQAAKAAVAAAQLDL 177 E L + ++ + + Q + +L+L Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNL 209 Score = 27.1 bits (60), Expect = 0.046 Identities = 12/85 (14%), Positives = 28/85 (32%), Gaps = 9/85 (10%) Query: 111 LDTAVAQLRQAEVLASQAQADFDRAERLVATGAVARKTYDDAASARNARQAQVQAAKAAV 170 L +QL Q E A+ ++ +L + + + Sbjct: 268 LRVYKSQLEQIESEILSAKEEYQLVTQLFKN---------EILDKLRQTTDNIGLLTLEL 318 Query: 171 AAAQLDLSYARVTAPIAGRVDRVLV 195 A + + + AP++ +V ++ V Sbjct: 319 AKNEERQQASVIRAPVSVKVQQLKV 343
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1067 bits (2761), Expect = 0.0 Identities = 433/1042 (41%), Positives = 654/1042 (62%), Gaps = 19/1042 (1%) Query: 5 RFFINRPIFAIVLSVLMLIAGAISYFQLPLSEYPQVTPPTVQVTASYPGANPQVIADTVA 64 FFI RPIFA VL++++++AGA++ QLP+++YP + PP V V+A+YPGA+ Q + DTV Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 SPLEQAVNGVEGMMYMQSQMSTDGRMVLTISFEQHIDPDVAQIQVQNRVSRALPRLPPEV 124 +EQ +NG++ +MYM S + G + +T++F+ DPD+AQ+QVQN++ A P LP EV Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 125 QRIGVVTDKTAPDILMVVHMLSPGDRYDPLYVSNYAMLNVRDELARLPGIANVIIGGEGE 184 Q+ G+ +K++ LMV +S +S+Y NV+D L+RL G+ +V + G + Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQ 181 Query: 185 YAMRVWLDPEKVASRGMTASDVVAAIREQNVQVAAGSIGQQPNASA-AFQVSVNALGRLT 243 YAMR+WLD + + +T DV+ ++ QN Q+AAG +G P S+ A R Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 244 TEEQFGDIVIKAGANGQVTRLRDVARLELGSDNYTMRGQLDGENAVGLQILMTPGSNALD 303 E+FG + ++ ++G V RL+DVAR+ELG +NY + +++G+ A GL I + G+NALD Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 304 TSSAVRATMERLQAKFPEGIEYKIAYDPTVFVRASLQSVAVTLLEAILLVVIVVVLFLQS 363 T+ A++A + LQ FP+G++ YD T FV+ S+ V TL EAI+LV +V+ LFLQ+ Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 364 WRASIIPLIAVPVSLVGTFAVMHMFGFSLNTLSLFGLVLSIGIVVDDAIVVVENVERHMA 423 RA++IP IAVPV L+GTFA++ FG+S+NTL++FG+VL+IG++VDDAIVVVENVER M Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 424 -LGESPKDAARKAMDEVTGPILAITSVLAAVFIPSAFLSGLQGEFYRQFALTIAFSTILS 482 PK+A K+M ++ G ++ I VL+AVFIP AF G G YRQF++TI + LS Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 483 AINSLTLSPALAAILLKPHHGAAKPDRLTRIIDGVFGGFFRRFNRFFDRASNSYVGGVRR 542 + +L L+PAL A LLKP ++ GGFF FN FD + N Y V + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENK---------GGFFGWFNTTFDHSVNHYTNSVGK 532 Query: 543 AVRGSAIVLLLYVGFLGLTWLGFHKVPAGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKE 602 + + LL+Y + + F ++P+ F+P +D+ + + QLP GA+ +RT+ V+ + Sbjct: 533 ILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQ 592 Query: 603 MTKIALA--EPGVESVVAFPGLSVNGPVNQPNTALMFAMLKPFDERKDPSLSAFAIQGKL 660 +T L + VESV G S +G N + F LKP++ER SA A+ + Sbjct: 593 VTDYYLKNEKANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRA 650 Query: 661 MGKFSQIPDGFVGIFPPPPVPGLGSMGGFKLQIEDRAGLGPEALAQAQGQIMGKAMQAP- 719 + +I DGFV F P + LG+ GF ++ D+AGLG +AL QA+ Q++G A Q P Sbjct: 651 KMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPA 710 Query: 720 ELANMLASFQTNAPQLQVDIDRVKAKSQGVSLTEVFDTLQVNLGSLYVNDFNRFGRTYRV 779 L ++ + + Q ++++D+ KA++ GVSL+++ T+ LG YVNDF GR ++ Sbjct: 711 SLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKL 770 Query: 780 MAQADAQFRMQAEDIGMLKVRNAAGDMIPLSAIATIERSSGPDRVMHYNGFPSADISGGP 839 QADA+FRM ED+ L VR+A G+M+P SA T G R+ YNG PS +I G Sbjct: 771 YVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEA 830 Query: 840 APGYSSGQATAAIEKIVSESLPDGMTYEWTDLTFQEKRVGNTAIYIFALAVLLAFLFLAA 899 APG SSG A A +E + S+ LP G+ Y+WT +++QE+ GN A + A++ ++ FL LAA Sbjct: 831 APGTSSGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAA 889 Query: 900 QYNSWSLPFAVLLIAPMALLSAIAGVWLSGGDNNIFTQIGFVVLVGLAAKNAILIVEFAR 959 Y SWS+P +V+L+ P+ ++ + L N+++ +G + +GL+AKNAILIVEFA+ Sbjct: 890 LYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAK 949 Query: 960 -AKESEGADPLAAVLEAARLRLRPILMTSFAFIAGVVPLVLASGAGAEMRHAMGIAVFAG 1018 E EG + A L A R+RLRPILMTS AFI GV+PL +++GAG+ ++A+GI V G Sbjct: 950 DLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGG 1009 Query: 1019 MLGVTVFGLVLTPVFYVVVRKL 1040 M+ T+ + PVF+VV+R+ Sbjct: 1010 MVSATLLAIFFVPVFFVVIRRC 1031 Score = 100 bits (251), Expect = 2e-23 Identities = 92/528 (17%), Positives = 179/528 (33%), Gaps = 53/528 (10%) Query: 548 AIVLLLYVGFLGLTWLGFHKVPAGFVPAQDKYYLVGIAQLPTGASLDRTEAVVKEMTKIA 607 A VL + + G L ++P P + A P GA + V +T+ Sbjct: 12 AWVLAIILMMAGA--LAILQLPVAQYPTIAPPAVSVSANYP-GAD---AQTVQDTVTQ-- 63 Query: 608 LAEPGVESVVAFPGLSVNGPVNQPNTALMFAMLKPFDERKDPSLSAFAIQGKLMGKFSQI 667 +++ L + ++ + F DP ++ +Q KL + Sbjct: 64 ---VIEQNMNGIDNLMYMSSTSDSAGSVTITLT--FQSGTDPDIAQVQVQNKLQLATPLL 118 Query: 668 PDGFVGIFPPPPVPGLGSMGGFKLQIE---DRAGLGPEALAQAQGQIMGKAMQAPELANM 724 P + S + + D G + ++ + L+ + Sbjct: 119 PQEV----QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNV-----KDTLSRL 169 Query: 725 --LASFQTNAPQLQVDI--DRVKAKSQGVSLTEVFDTLQVN--------LGSLYVNDFNR 772 + Q Q + I D ++ +V + L+V LG + Sbjct: 170 NGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQ 229 Query: 773 FGRTYRVMAQADAQFRMQ-AEDIGMLKVR-NAAGDMIPLSAIATIERSSGPDRVM-HYNG 829 + AQ R + E+ G + +R N+ G ++ L +A +E V+ NG Sbjct: 230 LNASII------AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARING 283 Query: 830 FPSADISGGPAPGYSSGQATAAIEKIVSE---SLPDGMTYEWT--DLTFQEKRVGNTAIY 884 P+A + A G ++ AI+ ++E P GM + F + + + + Sbjct: 284 KPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSI-HEVVK 342 Query: 885 IFALAVLLAFLFLAAQYNSWSLPFAVLLIAPMALLSAIAGVWLSGGDNNIFTQIGFVVLV 944 A++L FL + + + P+ LL A + G N T G V+ + Sbjct: 343 TLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAI 402 Query: 945 GLAAKNAILIVE-FARAKESEGADPLAAVLEAARLRLRPILMTSFAFIAGVVPLVLASGA 1003 GL +AI++VE R + P A ++ ++ + A +P+ G+ Sbjct: 403 GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGS 462 Query: 1004 GAEMRHAMGIAVFAGMLGVTVFGLVLTPVFYVVVRKLALRREARHARG 1051 + I + + M + L+LTP + K + G Sbjct: 463 TGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGG 510
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 30.1 bits (67), Expect = 0.022 Identities = 22/101 (21%), Positives = 40/101 (39%), Gaps = 10/101 (9%) Query: 234 RRAEIALRTAEANRAAYTRQAAKDRNALVLLLGQPLTP------ELSRQLDEAVALPDDI 287 R+AE R A RAA T + + + G+ L L++ + +A+A+ + Sbjct: 232 RKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRV 291 Query: 288 VPTDLPSGLPSELLARRPDIRAAEQMLIGANANIGAARAAF 328 + + PS + + R AEQ + + R A Sbjct: 292 LAS-APSVMAVGFASLTYSSRTAEQW---QDQTPDSVRYAL 328
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 5e-04 Identities = 57/324 (17%), Positives = 101/324 (31%), Gaps = 9/324 (2%) Query: 72 GRRNGYVVGVGFGVASGLIAALGIMLASFWIFCAGTFLAGFYGAYVQSYRFAAADTAEDA 131 GRR +V + I A W+ G +AG GA AD + Sbjct: 71 GRRPVLLVSLAGAAVDYAIMATA---PFLWVLYIGRIVAGITGATGAVAGAYIADITDGD 127 Query: 132 LKAKAISWVMVGGLAGAIIGPQLVIFTRDAVAGTPYVGSFLSQALLPLIALPILLMLRTP 191 +A+ ++ G + GP L P+ + L L +L Sbjct: 128 ERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 192 SQTQAEAVADSGRTVLQLLAMPRYLLAVAAGVVSYGVMAFVMTAAPVAMVNHGHSVDNAA 251 + A + + + A+ A ++ V A V D Sbjct: 188 ERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT 247 Query: 252 LGIQWHLLAMFGP---SFFTGRLMVRYGKERVTAVGMVLLAASGVVALGGLGLSHFWGSL 308 +GI + + TG + R G+ R +GM + +G + L + Sbjct: 248 IGISLAAFGILHSLAQAMITGPVAARLGERRALMLGM-IADGTGYILLAFATRGWMAFPI 306 Query: 309 ALLGIGWNLSFIGATAMVTDCHTPAERGKAQGMNDFFVFAATAAVSFLAGSI--LHSSGW 366 +L + AM++ +G+ QG + L +I + W Sbjct: 307 MVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTW 366 Query: 367 QAVNWMIFPALALILVPLLWQGRY 390 W+ AL L+ +P L +G + Sbjct: 367 NGWAWIAGAALYLLCLPALRRGLW 390
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 27.0 bits (59), Expect = 0.041 Identities = 16/70 (22%), Positives = 27/70 (38%), Gaps = 5/70 (7%) Query: 63 ILQFAHDRTPGPSASFYSPSAMAQRAERLSAGFQRRFAGRDLRELEAMLTEGQDRVLDCV 122 I Q A D +PG + Q + +SA + RD + + L+ +RVL+ Sbjct: 35 IQQAAEDSSPGAEVQKF-----VQSTDEMSAALAQFRNRRDYEKKSSNLSNSFERVLEDE 89 Query: 123 AHHSNASLFD 132 A + Sbjct: 90 ALPKAKQILK 99
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 32.6 bits (74), Expect = 0.004 Identities = 19/90 (21%), Positives = 26/90 (28%) Query: 399 ALLPGAAVATEKEPAASSRPDQSGGSHAIPPSTQRNPADPLESMLAMFETTPEPEQSVEA 458 A++ G + + P Q + P+ P + E PEPE E Sbjct: 27 AVVAGLLYTSVHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEP 86 Query: 459 PPEGADDAAVPLDPPASAPGPSAPTAAPAP 488 P E P P P P P Sbjct: 87 PKEAPVVIEKPKPKPKPKPKPVKKVEQPKR 116
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 27.9 bits (62), Expect = 0.008 Identities = 7/41 (17%), Positives = 15/41 (36%), Gaps = 5/41 (12%) Query: 36 VSKGMPRAGATALVWVAKLAVLGVLLYVAFWFALVMLGVAA 76 VS + +L+ A + ++ Y+ F + A Sbjct: 147 VSGELVWTAVWSLL----AATVVIMFYIWVRFEWQF-ALGA 182
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 28.7 bits (64), Expect = 0.033 Identities = 13/46 (28%), Positives = 20/46 (43%), Gaps = 12/46 (26%) Query: 168 SQSELARRLAADGFPVQRSHITRMAD---AVR---------YLLPA 201 +Q EL L DG+ V ++ ++R V+ Y LPA Sbjct: 21 TQDELVDILKKDGYNVTQATVSRDIKELHLVKVPTNNGSYKYSLPA 66
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 65.2 bits (159), Expect = 5e-13 Identities = 30/120 (25%), Positives = 49/120 (40%), Gaps = 9/120 (7%) Query: 832 SILLAEDHPFNRLTLTMQLESLGHRVTSTEDGEEAFERWQGEDFDVVITDGMMPRMDGYE 891 +IL+A+D R L L G+ V T + + D D+V+TD +MP + ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 892 LARRIRSQEALGGRRRCLVIALTASAEKDALERCLAAGMDRVLFKP----TTLDELARAL 947 L RI+ R V+ ++A + G L KP + + RAL Sbjct: 65 LLPRIKKA-----RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 2e-05 Identities = 20/82 (24%), Positives = 35/82 (42%), Gaps = 4/82 (4%) Query: 74 DDQVIGHCQLLFDRRNGVVRLARIALAPSARGQGLGLPMLEALLAEAFA-DADIERVELN 132 ++ IG ++ NG + IA+A R +G+G +L A +A + + L Sbjct: 73 ENNCIGRIKIR-SNWNGYALIEDIAVAKDYRKKGVGTALLH--KAIEWAKENHFCGLMLE 129 Query: 133 VYDWNAAARHLYRRAGFREEGL 154 D N +A H Y + F + Sbjct: 130 TQDINISACHFYAKHHFIIGAV 151
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 106 bits (265), Expect = 6e-27 Identities = 32/154 (20%), Positives = 69/154 (44%), Gaps = 5/154 (3%) Query: 14 RFSVLLVDDEPLILSSLRRLLRNQPYDLLLAESGEQALQLLESRPVDLVVSDARMPNMDG 73 ++L+ DD+ I + L + L YD+ + + + + + DLVV+D MP+ + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 74 AALLAEIHRRSPETIRILLTGHADLPTIAKAINEGRIHHYLSKPWNDDELLLTLRQSLEY 133 LL I + P+ ++++ T KA +G + YL KP++ EL+ + ++L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKG-AYDYLPKPFDLTELIGIIGRALAE 121 Query: 134 LHSERERRRLERLTQE----QNDRLQQLNATLEK 163 + + ++ +Q++ L + Sbjct: 122 PKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 5e-04 Identities = 29/188 (15%), Positives = 63/188 (33%), Gaps = 44/188 (23%) Query: 288 REGIGRVRKIVQDLKNFSR-VDAEDDWQWTDLHQGIESTLNIVASE-------LKYRADV 339 E + R+++ L R + + L + + + L++ + Sbjct: 187 LEDPTKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDRLQFENQI 246 Query: 340 VREYGDLPEVKCLPSQINQVVMNLVMNAAQ-AMGPER--GRIVIRTGHTVEHAWIEVEDS 396 D+ +P + Q LV N + + G+I+++ +EVE++ Sbjct: 247 NPAIMDVQ----VPPMLVQT---LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENT 299 Query: 397 GQGISPEILPRIFDPFFTTKPVGKGTGLGLS-------LSYGIVQKHGGTIEVRSQPGVG 449 G K + TG GL + YG + I++ + G Sbjct: 300 GSLA--------------LKNTKESTGTGLQNVRERLQMLYG--TEAQ--IKLSEKQGKV 341 Query: 450 SAFRIVLP 457 +A +++P Sbjct: 342 NA-MVLIP 348
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.8 bits (106), Expect = 5e-07 Identities = 31/172 (18%), Positives = 65/172 (37%), Gaps = 16/172 (9%) Query: 124 TYKAALAQAEGTLMQNQAQLKNAEIDLQRYKGLYAEDSIAKQTLDTQEAQVRQLQGTIRT 183 L + L Q ++++ +A+ + Q L+ + + ++RQ I Sbjct: 263 EAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILD---------KLRQTTDNIGL 313 Query: 184 NQGQVDDARLNLTFTEVRAPISGR-LGLRQVDIGNLVTSGDTTPLVVITQVKPISVVFSL 242 ++ + +RAP+S + L+ G +VT+ +T +V++ + + V + Sbjct: 314 LTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTALV 372 Query: 243 PQQQIGTVVEQMNGPGKLTVTALDRNQDKVLAEGTLT--TLDNQIDTTTGTV 292 + IG + + V A + L G + LD D G V Sbjct: 373 QNKDIGFINVGQ--NAIIKVEAFPYTRYGYL-VGKVKNINLDAIEDQRLGLV 421 Score = 41.4 bits (97), Expect = 6e-06 Identities = 26/125 (20%), Positives = 49/125 (39%), Gaps = 8/125 (6%) Query: 80 ALGTVTAF-NTVNVKPRVNGELVKVLFQEGQEVKAGDLLAVVDPRTYKAALAQAEGTLMQ 138 A G +T + +KP N + +++ +EG+ V+ GD+L + +A + + +L+Q Sbjct: 86 ANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQ 145 Query: 139 NQAQL--KNAEIDLQRYKGLYAEDSIAKQTLDT-QEAQVRQLQGTIR----TNQGQVDDA 191 + + L + E +V +L I+ T Q Q Sbjct: 146 ARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK 205 Query: 192 RLNLT 196 LNL Sbjct: 206 ELNLD 210
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 840 bits (2171), Expect = 0.0 Identities = 301/1036 (29%), Positives = 514/1036 (49%), Gaps = 29/1036 (2%) Query: 4 SRPFILRPVATTLLMVAILLSGLIAYRFLPISALPEVDYPTIQVVTLYPGASPEIMTSSI 63 + FI RP+ +L + ++++G +A LP++ P + P + V YPGA + + ++ Sbjct: 2 ANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTV 61 Query: 64 TAPLENQLGQIPGLNEMSSSS-SGGASVITLQFSLQSNLDVAEQEVQAAINAAQSLLPND 122 T +E + I L MSS+S S G+ ITL F ++ D+A+ +VQ + A LLP + Sbjct: 62 TQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQE 121 Query: 123 LPNQPVFSKVNPADAPILTLAVMSDG--MPLPQIQDLVDTRLAQKISQISGVGLVSISGG 180 + Q + S + + ++ +SD I D V + + +S+++GVG V + G Sbjct: 122 VQQQGI-SVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QRPAVRVRANPTALAAAGLSLEDLRSTVTSNNLNGPKGSFDGPTRAS------TLDANDQ 234 Q A+R+ + L L+ D+ + + N G G ++ A + Sbjct: 181 QY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239 Query: 235 LRSADAYRDLII-AYKNGSPLRIRDVASVEDDAENVRLAAWANNLPAVVLNIQRQPGANV 293 ++ + + + + +GS +R++DVA VE EN + A N PA L I+ GAN Sbjct: 240 FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299 Query: 294 IEVVDRIKALLPQLQSTLPGNLDVQVLTDRTTTIRASVKDVQFELALAVALVVMVTFLFL 353 ++ IKA L +LQ P + V D T ++ S+ +V L A+ LV +V +LFL Sbjct: 300 LDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFL 359 Query: 354 RNVYATLIPSFAVPLSLIGTFGVMYLSGFSINNLTLMALTIATGFVVDDAIVMVENIARY 413 +N+ ATLIP+ AVP+ L+GTF ++ G+SIN LT+ + +A G +VDDAIV+VEN+ R Sbjct: 360 QNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERV 419 Query: 414 L-EQGDSPLEAALKGSKQIGFTIISLTFSLIAVLIPLLFMGDVAGRLFREFAITLAVAIL 472 + E P EA K QI ++ + L AV IP+ F G G ++R+F+IT+ A+ Sbjct: 420 MMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMA 479 Query: 473 ISGFVSLTLTPMLSAKLLRHIDEDQQ---GRFARAAGRVIDGLIAQYAKALRVVLRHQPL 529 +S V+L LTP L A LL+ + + G F D + Y ++ +L Sbjct: 480 LSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 530 TLLVAIATLALTALLYLAMPKGFFPVQDTGVIQGVAEAPQSISFQAMSERQRALAEVVLK 589 LL+ +A +L+L +P F P +D GV + + P + + + + + LK Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 590 DPA--VASLSSYIGVDGSNPTLNTGRLLINLKPHSERDV---TASEVIQRLQPELDHLPG 644 + V S+ + G S N G ++LKP ER+ +A VI R + EL + Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 645 IKLYMQPVQDLTIEDRVARTQYQFTLQD---ADPDVLAEWVPKLVARLQELP-QLADVAS 700 + P I + T + F L D D L + +L+ + P L V Sbjct: 660 GFVI--PFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRP 717 Query: 701 DWQDKGLQAYLNIDRDTASRLGVKLSDIDSVLYNAFGQRLISTIFTQATQYRVVLEVAPQ 760 + + Q L +D++ A LGV LSDI+ + A G ++ + ++ ++ + Sbjct: 718 NGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAK 777 Query: 761 FQLGPQALEQLYVPSSDGTQVRLSSLAKVEERHTLLAINHIAQFPSATLSFNLAKGYSLG 820 F++ P+ +++LYV S++G V S+ + + PS + A G S G Sbjct: 778 FRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSG 837 Query: 821 EAVEAIRGVEASLELPLSMQGSFRGAALAFEASLSNTLLLILASVVTMYIVLGILYESFI 880 +A+ + + + +LP + + G + S + L+ S V +++ L LYES+ Sbjct: 838 DAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 881 HPVTILSTLPSAGVGALLALMLAGQEIGIVAIIGIILLIGIVKKNAIMMIDFALDAERNE 940 PV+++ +P VG LLA L Q+ + ++G++ IG+ KNAI++++FA D E Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 941 GKPPHEAIYQACLLRFRPILMTTMAALLGALPLMLAGGAGAELRQPLGITMVGGLLLSQV 1000 GK EA A +R RPILMT++A +LG LPL ++ GAG+ + +GI ++GG++ + + Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1001 LTLFTTPVIYLYFDRL 1016 L +F PV ++ R Sbjct: 1016 LAIFFVPVFFVVIRRC 1031
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 814 bits (2105), Expect = 0.0 Identities = 289/1032 (28%), Positives = 511/1032 (49%), Gaps = 31/1032 (3%) Query: 7 FIRRPVATTLLTLALLLAGTLSFGLLPVAPLPNVDFPAIVVSASLPGASPETMASSVATP 66 FIRRP+ +L + L++AG L+ LPVA P + PA+ VSA+ PGA +T+ +V Sbjct: 5 FIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQV 64 Query: 67 LERSLGRIAGISEMTSSS-SLGSTTVVLVFDLEKDIDGAAREVQAAINGAMSLLPSGMPN 125 +E+++ I + M+S+S S GS T+ L F D D A +VQ + A LLP + Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQQ 124 Query: 126 NPSYRKANPSDMPIMVLTLTSET--QSRGEMYDLASTVLAPKLSQVQGVGQVSIGGSSLP 183 S +MV S+ ++ ++ D ++ + LS++ GVG V + G+ Sbjct: 125 -QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY- 182 Query: 184 AVRVDLNPDAMSQYGLSLDSVRTAIAAANSNGPKG------AVEKDDKHWQVDANDQLRK 237 A+R+ L+ D +++Y L+ V + N G A+ + + A + + Sbjct: 183 AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFKN 242 Query: 238 AREYEPLVIHYNADNGAAVRLGDVAKVSDSVEDVRNAGFSDDLPAVLLIVTRQPGANIIE 297 E+ + + N+D G+ VRL DVA+V E+ + PA L + GAN ++ Sbjct: 243 PEEFGKVTLRVNSD-GSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 298 ATDAIHAQLPVLQELLGPQVKLNVMDDRSPSIRASLEEAELTLLISVALVILVVFLFLRN 357 AI A+L LQ +K+ D +P ++ S+ E TL ++ LV LV++LFL+N Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 358 GRATLIPSLAVPVSLIGTFAVMYLCDFSLNNLSLMALIIATGFVVDDAIVVVENIARRI- 416 RATLIP++AVPV L+GTFA++ +S+N L++ +++A G +VDDAIVVVEN+ R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 417 EEGDPPIQAAITGARQVGFTVLSMTLSLVAVFIPLLLMGGLTGRLFREFAVTLSAAILVS 476 E+ PP +A Q+ ++ + + L AVFIP+ GG TG ++R+F++T+ +A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 477 LVVSLTLTPMLCARLLRPLKRPEG---ASLARRSDRFFAAFMLRYRASLGWALEHSRLMV 533 ++V+L LTP LCA LL+P+ + F + Y S+G L + + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 534 VIMLACIAMNLWLFVVVPKGFLPQQDSGRLRGYAVADQSISFQSLSAKMGEYRKILSSDP 593 +I +A + LF+ +P FLP++D G + + + + + Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 594 AVE-----NVVGFIGGGRWQSSNTGSFFVTLKPIGERDP----VEKVLTRLRERIAKVPG 644 V GF G Q+ N G FV+LKP ER+ E V+ R + + K+ Sbjct: 602 KANVESVFTVNGFSFSG--QAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 645 AALYLNAGQDVRLGGRDSNAQYEFTLRS-DDLTLLREWAPKVEAAMRKLP-QLVDVNSDS 702 + + G + +E ++ L + ++ + P LV V + Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 703 QDKGVQTRLVIDRDRAATLGINVEMVDAVLNDSFGQRQVSTIFNPLNQYRVVMEVDQQYQ 762 + Q +L +D+++A LG+++ ++ ++ + G V+ + ++ ++ D +++ Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 763 QSPEILRQVQVIGNDGQRVPLSAFSHYEPSRAPLEVNHQGQFAATTLSFNLAPGAQIGPT 822 PE + ++ V +G+ VP SAF+ + + + APG G Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 823 REAIMQALEPLHIPVDVQTSFEGNAGAVQDTQNQMPWLILLALLAVYIVLGILYESYVHP 882 + L P + + G + + + NQ P L+ ++ + V++ L LYES+ P Sbjct: 840 MALMENLASKL--PAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIP 897 Query: 883 LTILSTLPSAGVGALLALILCRSELSLIALIGIILLIGIVKKNAIMMIDFALEAERNHGL 942 ++++ +P VG LLA L + + ++G++ IG+ KNAI++++FA + G Sbjct: 898 VSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGK 957 Query: 943 SPREAILEACMMRFRPIMMTTLAALLGALPLIFGIGGDAALRRPLGITIVGGLIGSQLLT 1002 EA L A MR RPI+MT+LA +LG LPL G + + +GI ++GG++ + LL Sbjct: 958 GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLA 1017 Query: 1003 LYTTPVVYLYLD 1014 ++ PV ++ + Sbjct: 1018 IFFVPVFFVVIR 1029
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.3 bits (89), Expect = 6e-05 Identities = 25/216 (11%), Positives = 62/216 (28%), Gaps = 30/216 (13%) Query: 229 RADVAQARTQLKSTQAQAIDLKYQ--RAQLEHAIAVLVGLPPAQFNLPPVASVPKLPDLP 286 + A TQ+ + + + R Q+ L LP + P ++ Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 287 AVVP----------SQLLERRPDIASAERKVISANAQIGVAKAAY------FPDLTLSAA 330 + +Q ++ ++ + ++ A+I + D + Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 331 GGYRSGSLSNWISTPNRFWSIGPQFAMTLFDGGLIGSQVDQAEATYDQTVATYRQTVLDG 390 + + N++ + + I S++ A+ Y ++ +LD Sbjct: 246 KQA--IAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK 303 Query: 391 FREVEDYLVQLSVLDEESGVQREALESAREALRLAE 426 R+ D + L L E + + Sbjct: 304 LRQTTDNIGLL----------TLELAKNEERQQASV 329 Score = 31.3 bits (71), Expect = 0.009 Identities = 18/150 (12%), Positives = 43/150 (28%), Gaps = 18/150 (12%) Query: 171 ASAADLAAVRLSQQSQLAQNYLQLRVMDEQIRLLNDTVTAYERSLKVAENK-------YR 223 + + + Q+Q Q L L + + + YE +V +++ Sbjct: 186 RLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLH 245 Query: 224 AGIVTRADVAQARTQLKSTQAQAIDLKYQRAQLEHAIAVLVGLPPAQFNLPPVASVPKLP 283 + + V + + + K Q Q+E I A+ V Sbjct: 246 KQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILS------AKEEYQLVTQ----- 294 Query: 284 DLPAVVPSQLLERRPDIASAERKVISANAQ 313 + +L + +I ++ + Sbjct: 295 LFKNEILDKLRQTTDNIGLLTLELAKNEER 324
>PF06580#Sensor histidine kinase Length = 349 Score = 35.6 bits (82), Expect = 3e-04 Identities = 25/105 (23%), Positives = 40/105 (38%), Gaps = 24/105 (22%) Query: 370 LVSNAVRH----TPQGGRIDVRIGERAGHTEVRVSNDGPGIPPEYLPHLFERFYRRAGRQ 425 LV N ++H PQGG+I ++ + G + V N G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN---------------- 306 Query: 426 TGAQAGTGLGLAIV-QSIMAYHGGRAEAE-SVPQQKTHLRLLFPS 468 + TG GL V + + +G A+ + S Q K + +L P Sbjct: 307 --TKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 80.6 bits (199), Expect = 7e-20 Identities = 34/145 (23%), Positives = 63/145 (43%), Gaps = 8/145 (5%) Query: 2 RILIIEDEVKTADYLHQGLTESGYIVDRANDGIDGLHMALQHPYELVILDVNLPGIDGWD 61 IL+ +D+ L+Q L+ +GY V ++ +LV+ DV +P + +D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLRRLRER-SSARVMMLTGHGRLTDKVRGLDLGADDFMVKPFQFPELLARVRSLLRRHDQ 120 LL R+++ V++++ ++ + GA D++ KPF EL+ + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE--- 121 Query: 121 APMQDVLRVADLELDASRHRAFRGR 145 R + LE D+ GR Sbjct: 122 ----PKRRPSKLEDDSQDGMPLVGR 142
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 46.0 bits (109), Expect = 2e-07 Identities = 40/212 (18%), Positives = 82/212 (38%), Gaps = 22/212 (10%) Query: 216 ISSPQLSDQRSEFAAAQRRLSLAQSTYKREQQLWKEGISAEQEFLLARQGLQ-EAEIALN 274 I+ + +Q +++ A L + +S + +Q+ E +SA++E+ L Q + E L Sbjct: 249 IAKHAVLEQENKYVEAVNELRVYKS---QLEQIESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 275 NARAKIAALGG--NPSLQGGNRYELRAPFAGVLVE-KHLTQGEPVDGTANVFTLS-DLSS 330 I L + + +RAP + + + K T+G V + + + + Sbjct: 306 QTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDT 365 Query: 331 VWATFNVPAQLLGQVRVGSKVKVLAQALDS----EVEGTVSYIG-DLLGEQTRAATARVT 385 + T V + +G + VG + +A + G V I D + +Q V Sbjct: 366 LEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVI 425 Query: 386 LSNPEST---------WRPGLFVSVQVAEATR 408 +S E+ G+ V+ ++ R Sbjct: 426 ISIEENCLSTGNKNIPLSSGMAVTAEIKTGMR 457 Score = 31.3 bits (71), Expect = 0.010 Identities = 19/119 (15%), Positives = 42/119 (35%), Gaps = 13/119 (10%) Query: 168 LAQVVSLPGEIRFNEDRTAHIVPRLPGIVDSVPANLGQAVKQGELLAVISSPQLSDQRSE 227 + V + G++ + I P IV + G++V++G++L +++ ++ Sbjct: 80 VEIVATANGKLTHSGRSKE-IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGA---EAD 135 Query: 228 FAAAQRRLSLAQSTYKREQQLWKE---------GISAEQEFLLARQGLQEAEIALNNAR 277 Q L A+ R Q L + + E F + +L + Sbjct: 136 TLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQ 194
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 811 bits (2097), Expect = 0.0 Identities = 237/1055 (22%), Positives = 435/1055 (41%), Gaps = 56/1055 (5%) Query: 5 IIQFAIEQRWLVLLAVLGMAGVGIGSYQKLSIDAVPDITNVQVQINTAAPGYSPLEVEQR 64 + F I + + + + G + +L + P I V ++ PG V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 ITYPVETVMAGLPGLQETRSLS-RPGISQVTVIFEEGTDIYFARQQVNERLSTAREQLPE 123 +T +E M G+ L S S G +T+ F+ GTD A+ QV +L A LP+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 124 DISPTLGPISTGLGEIYLWTVEAEEGATKEDGSAYTPTDLRTIQDWIIRPQLRNVKGVAE 183 ++ + YL D T D+ ++ L + GV + Sbjct: 121 EVQQQGISVEKSSS-SYLMVA-----GFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGD 174 Query: 184 INTIGGYAKQFLIAPDPKKLAAYKLTLGDLQNAVLRNNENVGAGYI------ERRGEQLL 237 + G I D L YKLT D+ N + N+ + AG + + Sbjct: 175 VQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 238 IRAPGQVKDMDDIRGIIV-SNVDGVPIRIRDVAEVGLGKELRTGAATENGREVVLGTVFM 296 I A + K+ ++ + + N DG +R++DVA V LG E A NG+ + + Sbjct: 234 IIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKL 293 Query: 297 LIGENSREVAQAVGQRLEEINRTLPKGVKAITVYDRTTLVDKAVATVKKNLVEGAALVIA 356 G N+ + A+A+ +L E+ P+G+K + YD T V ++ V K L E LV Sbjct: 294 ATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFL 353 Query: 357 VLFLFLGNIRAALITATIIPLSMLFTFTGMVGNRVSANLMSLG--ALDFGIIVDGAVVIV 414 V++LFL N+RA LI +P+ +L TF + S N +++ L G++VD A+V+V Sbjct: 354 VMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVV 413 Query: 415 ENAIRRLAHAQAHHGRQLTRAERFHEVFAASREARRALVFGQIIIMVVYLPIFALTGVEG 474 EN + + + + ALV +++ V++P+ G G Sbjct: 414 EN---------VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTG 464 Query: 475 KMFHPMAFTVVTALLGAMILSVTFVPAAIALFITGKVKEEE----------NFVMRRARL 524 ++ + T+V+A+ ++++++ PA A + E N + Sbjct: 465 AIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVN 524 Query: 525 AYEPALRWVLGHRALVVGGALGAILLTGLVASRMGSEFIPSLSEGDFAMQGLRVPGTSL- 583 Y ++ +LG + + ++ R+ S F+P +G F G + Sbjct: 525 HYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQE 584 Query: 584 -TQSVEMQQTLERKLMGKFPEIERVFARTGTAEIASDLMPPNASDSYVMLKPQSQWPDPK 642 TQ V + Q + L + +E VF G + NA ++V LKP + + Sbjct: 585 RTQKV-LDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDE 640 Query: 643 KSREALLEELQAAALEVP-GSVYEFSQPIQLRFNELISGVRSDVA-VKVFGDDMQVLNDT 700 S EA++ + ++ G V F+ P EL + D + G L Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGTATGFDFELIDQAGLGHDALTQA 697 Query: 701 AEKI-SKVLQGIDGASEVKVEQTTGLPVLTVDIDRDKAARFGLNVGDIQDTVATALGGRN 759 ++ Q V+ +++D++KA G+++ DI T++TALGG Sbjct: 698 RNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTY 757 Query: 760 AGTLFEGDRRFDIVIRLPETLRADLPALSNLLIPLPPNNLARIDFIPLSDVARLDLSPGP 819 + R + ++ R + L + + +P S G Sbjct: 758 VNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANG-----EMVPFSAFTTSHWVYGS 812 Query: 820 NQISRENGKRRIVVSANVRGRDIGSFVLEAQQKLQDGVKIPAGYWTTWGGQFEQLQSAAK 879 ++ R NG + + + + L K+PAG W G Q + + Sbjct: 813 PRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGN 870 Query: 880 RLQVVVPVALLLVFTLLFAMFNNVKDGLLVFTGIPFALTGGVLALWLRGIPLSISAAVGF 939 + +V ++ ++VF L A++ + + V +P + G +LA L + VG Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGL 930 Query: 940 IALSGVAVLNGLVMISFIRNLL-QEGRSLDQAVWEGAITRLRPVLMTALVASLGFVPMAL 998 + G++ N ++++ F ++L+ +EG+ + +A RLRP+LMT+L LG +P+A+ Sbjct: 931 LTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAI 990 Query: 999 ATGTGAEVQRPLATVVIGGILSSTMLTLLVLPVLY 1033 + G G+ Q + V+GG++S+T+L + +PV + Sbjct: 991 SNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFF 1025 Score = 70.6 bits (173), Expect = 2e-14 Identities = 70/527 (13%), Positives = 160/527 (30%), Gaps = 46/527 (8%) Query: 2 FERIIQFAIEQRWLVLLAVLGMAGVGIGSYQKLSIDAVPDITNVQVQINTAAPGYSPLEV 61 + + + LL + + + +L +P+ P + E Sbjct: 526 YTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQER 585 Query: 62 EQRI---------TYPVETVMA--GLPGLQETRSLSRPGISQVTV-IFEEGTDIYFARQQ 109 Q++ V + + G + G++ V++ +EE + + Sbjct: 586 TQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEA 645 Query: 110 VNERLSTAREQLPED-ISPTLGPISTGLGEIYLWTVEAEEGATKEDGSAYTPTDLRTIQD 168 V R ++ + + P P LG D + L ++ Sbjct: 646 VIHRAKMELGKIRDGFVIPFNMPAIVELG------TATGFDFELIDQAGLGHDALTQARN 699 Query: 169 WIIRPQLRNVKGVAEINTIGGY-AKQFLIAPDPKKLAAYKLTLGDLQNAVLRNNENVGAG 227 ++ ++ + + G QF + D +K A ++L D+ + Sbjct: 700 QLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVN 759 Query: 228 YIERRGEQ--LLIRAPGQ-VKDMDDIRGIIVSNVDGVPIRIRDVAEVGLGKELRTGAAT- 283 RG L ++A + +D+ + V + +G + G+ Sbjct: 760 DFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTS----HWVYGSPRL 815 Query: 284 --ENGREVVLGTVFMLIGENSREVAQAVGQRLEEINRTLPKGVKAITVYDRTTLVDKAVA 341 NG + G +S + + E + LP G+ + + Sbjct: 816 ERYNGLPSMEIQGEAAPGTSSGDAMALM----ENLASKLPAGI-GYDWTGMSYQERLSGN 870 Query: 342 TVKKNLVEGAALVIAVLFLFLGNIRAALITATIIPLSMLFTFTGMVGNRVSANLMSLGAL 401 + +V L + + ++PL ++ ++ + L Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGL 930 Query: 402 --DFGIIVDGAVVIVENAIRRLAHAQAHHGRQLTRAERFHEVFAASREARRALVFGQIII 459 G+ A++IVE A G+ + A A R R ++ + Sbjct: 931 LTTIGLSAKNAILIVEFAK----DLMEKEGKGVVEA-----TLMAVRMRLRPILMTSLAF 981 Query: 460 MVVYLPIFALTGVEGKMFHPMAFTVVTALLGAMILSVTFVPAAIALF 506 ++ LP+ G + + V+ ++ A +L++ FVP + Sbjct: 982 ILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVI 1028
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 100 bits (250), Expect = 1e-27 Identities = 74/253 (29%), Positives = 108/253 (42%), Gaps = 15/253 (5%) Query: 8 KVALVSGAAQGIGLGVVRRLLEEGARVVAVDRSELVHELAGDACLCLT-------ADLER 60 K+A ++GAAQGIG V R L +GA + AVD + E + AD+ Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 61 YAECQRVLERTLERFGRLDILVNNVGGTLWAKPYQHYAEDEIEAELRRSLLPTLWCCRAA 120 A + R G +DILVN V G L +++E EA + R+ Sbjct: 69 SAAIDEITARIEREMGPIDILVN-VAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 121 LPAMLGQGSGAIVNVSSVATRGVNRV---PYGAAKGGVNALTACLAFETADQGIRVNAVA 177 M+ + SG+IV V S GV R Y ++K T CL E A+ IR N V+ Sbjct: 128 SKYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 178 PGGTDAPPRRIPRNAAAQSEEERRWYRQIVEQTLDSSLMKRYGSIDEQVAAILFLASDEA 237 PG T+ + + A + + +E +K+ + A+LFL S +A Sbjct: 187 PGSTETD---MQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 238 SYITGVTLPVAGG 250 +IT L V GG Sbjct: 244 GHITMHNLCVDGG 256
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 29.5 bits (66), Expect = 0.025 Identities = 19/61 (31%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 114 LIASAALAGSGVAIIQALVPGVVKRWFPR-RVPAAMGLYSASLMAGGGTAAVLSPRIAEH 172 LI + + G+G A ALV VV R+ P+ A GL + + G G + IA + Sbjct: 106 LIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHY 165 Query: 173 F 173 Sbjct: 166 I 166
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 61.4 bits (149), Expect = 3e-12 Identities = 21/104 (20%), Positives = 44/104 (42%) Query: 64 SVELRPRVSGYIDRVAFHEGALVKKGDLLFQIDPRPFEAEVKRLEAQLQQARAAQARSVN 123 S E++P + + + EG V+KGD+L ++ EA+ + ++ L QAR Q R Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI 155 Query: 124 EAQRGERLRASNAISAELADARTTAAQEAKAAVAATQAQLDAAR 167 ++ E + + + + +E + + Q + Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Score = 46.0 bits (109), Expect = 2e-07 Identities = 18/122 (14%), Positives = 39/122 (31%), Gaps = 10/122 (8%) Query: 84 ALVKKGDLLFQIDPRPFEAEVKRLEAQLQQARAAQARSVNEAQRGERLRASNAISAELAD 143 +L+ K + + E + + + + + E L A Sbjct: 242 SLLHKQAI-----AKHAVLEQENKYVEAVNELRVYKSQLEQIES-EILSAKEEYQLVTQL 295 Query: 144 ARTTAAQ---EAKAAVAATQAQLDAARLNLSFTRITAPIDGRVSRAEV-TAGNLVNSGET 199 + + + +L + I AP+ +V + +V T G +V + ET Sbjct: 296 FKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAET 355 Query: 200 LL 201 L+ Sbjct: 356 LM 357
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.8 bits (121), Expect = 4e-10 Identities = 37/201 (18%), Positives = 66/201 (32%), Gaps = 11/201 (5%) Query: 1 MAKRGRPCGFD-REQALRRALDVFWEAGYEGATMAALKEAMGGICAPSMYAAYGSKEALF 59 MA++ + + R+ L AL +F + G ++ + +A G+ ++Y + K LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAA-GVTRGAIYWHFKDKSDLF 59 Query: 60 RSAVELYLSQECQLSKGAFA------LPTARESIAALLESAAVSYTTEGKPRGCLVDLST 113 EL S +L A L RE + +LES T E + + Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLEST---VTEERRRLLMEIIFHK 116 Query: 114 TNFSPANKGVEDYLRDHRRRAARLLRERFARGVADGDVPAGADLDALTSFYSSVLQGLSI 173 F V+ R+ + + + + +PA + GL Sbjct: 117 CEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLME 176 Query: 174 QARDGASRQQLLAIGRCAMAA 194 L R +A Sbjct: 177 NWLFAPQSFDLKKEARDYVAI 197
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 82.6 bits (204), Expect = 2e-20 Identities = 38/122 (31%), Positives = 62/122 (50%), Gaps = 1/122 (0%) Query: 2 HVLLTEDDDLIASGIVAGLNAQGLTVDRVASAADTQALLQVARFDVLVLDLGLPDEDGLR 61 +L+ +DD I + + L+ G V ++AA + D++V D+ +PDE+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 LLQRLRQQGVDLPVLVLTARDAVTDRVAGLQAGADDYLLKPFDLRELGARLHT-LQRRSA 120 LL R+++ DLPVLV++A++ + + GA DYL KPFDL EL + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GR 122 Sbjct: 125 RP 126
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 48.7 bits (116), Expect = 3e-08 Identities = 39/178 (21%), Positives = 72/178 (40%), Gaps = 3/178 (1%) Query: 31 LCFLIVAMDGFDTAAIGFIAPALAHDWQLSPAQLSPILGAALAGLALGAFAAGPLADRFG 90 LC L + + P +A+D+ PA + + A + ++G G L+D+ G Sbjct: 19 LCIL-SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLG 77 Query: 91 RKSVLLLSVLFFGGWSLASAYAGS-AETLALLRFFTGLGLGGAMPNAITLTSEYCPRRHR 149 K +LL ++ S+ S L + RF G G + + + Y P+ +R Sbjct: 78 IKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENR 137 Query: 150 ALMVTAMFCGFTLGSALGGLLAARMVPALGWESVLLLGGGLPLASLPLLWACLPESVR 207 + +G +G + + + W S LLL + + ++P L L + VR Sbjct: 138 GKAFGLIGSIVAMGEGVGPAIGGMIAHYIHW-SYLLLIPMITIITVPFLMKLLKKEVR 194 Score = 30.6 bits (69), Expect = 0.014 Identities = 36/196 (18%), Positives = 71/196 (36%), Gaps = 13/196 (6%) Query: 256 AELRGGTLLLWATF--FMGLLIIYLLTNWLPTLIGGTGFSLGEAATISAMFQLGGTLGAL 313 + LR +L+W F +L +L LP + ++ F L ++G Sbjct: 8 SNLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTA 67 Query: 314 LLGSAMDRFDAHRVLSLAYVGGALFILG--IASLYHSFA---LLALCVAGVGFCISGSQV 368 + G D+ R+L G + G I + HSF ++A + G G + V Sbjct: 68 VYGKLSDQLGIKRLLLF---GIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALV 124 Query: 369 GANALAADFYPTRSRATGVSWALGLGRIGSIVGSLSGGALLG-LGLGFSGILALLVIPAL 427 + A + P +R + +G VG GG + + + ++ ++ I + Sbjct: 125 M--VVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITV 182 Query: 428 LAAVAVHRLGRRRARP 443 + + + R Sbjct: 183 PFLMKLLKKEVRIKGH 198
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 27.7 bits (61), Expect = 0.030 Identities = 13/43 (30%), Positives = 20/43 (46%) Query: 59 RGLRPTPYGMTLFNHAQRVLTEMERARQNLEAMRSGSGSRVLL 101 PTP G+ L N +T + R ++ R+ SG+ V L Sbjct: 76 VSWSPTPDGIWLMNAEGTGITHLNRQKEGEYTGRTPSGADVTL 118
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 34.1 bits (78), Expect = 0.002 Identities = 19/81 (23%), Positives = 26/81 (32%), Gaps = 10/81 (12%) Query: 15 LDFPRASRLSRSVRAALLSLAMAAGAAPLCASAAEAAAEQARPYAIPAGQ--LGDVLNRF 72 + FP S R + LL L+ + A L PY A L D+L F Sbjct: 1 MAFPLHSFFKRVLTGTLLLLSSYSWAQEL--------DWLPIPYVYVAKGESLRDLLTDF 52 Query: 73 AREAGITLSATPAQTGGYSSQ 93 T+ + S Q Sbjct: 53 GANYDATVVVSDKINDKVSGQ 73
>PF05860#haemagglutination activity domain. Length = 117 Score = 81.4 bits (201), Expect = 9e-20 Identities = 23/130 (17%), Positives = 47/130 (36%), Gaps = 23/130 (17%) Query: 34 DKAAGGNTGLGQAGNGVPIVNIATPNGAGLSNNHFRDYNVGANGLILNNATGKTQGTQLG 93 D N+ + I+ T G+ L ++ F++++V +G N Sbjct: 6 DTTLPINSNI-TTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFNNPT-------- 55 Query: 94 GIILGNPNLKGQAAQVILNQVTGGNRSTLAGYTEVAGQSARVIVANPHGITCQGCGFINT 153 Q I+++VTGG+ S + G A + + NP+GI ++ Sbjct: 56 ------------NIQNIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGIIFGQNARLDI 102 Query: 154 PRATLTTGKP 163 + + + Sbjct: 103 GGSFVGSTAN 112
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 33.0 bits (75), Expect = 4e-04 Identities = 18/68 (26%), Positives = 27/68 (39%), Gaps = 4/68 (5%) Query: 103 LSHAYRRRGLGAHLFHLAATQARHLGASGLYVSATPSQN--TVDFYTRLGCRLCMEPDEE 160 ++ YR++G+G L H A A+ GL + T N FY + + D Sbjct: 97 VAKDYRKKGVGTALLHKAIEWAKENHFCGLMLE-TQDINISACHFYAKHHFIIG-AVDTM 154 Query: 161 LYRLEPED 168 LY P Sbjct: 155 LYSNFPTA 162
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 331 bits (851), Expect = e-111 Identities = 120/355 (33%), Positives = 179/355 (50%), Gaps = 35/355 (9%) Query: 186 ERLAALHHDHAEGFEMLLGDSQPIRTLKTRAQRVAALDAPLLIHGETGTGKELVARGCHA 245 +R + D ++ L+G S ++ + R+ D L+I GE+GTGKELVAR H Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 246 LSARHNSPFLALNCAALPENLAESELFGYAPGAFTGAQRGGKPGLLELAHQGTVFLDEIG 305 R N PF+A+N AA+P +L ESELFG+ GAFTGAQ G E A GT+FLDEIG Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRST-GRFEQAEGGTLFLDEIG 241 Query: 306 EMSPYLQAKLLRFLSDGSFRRVGGDREVRVDVRILSATHRNLEKMVAEGSFREDLFYRLN 365 +M Q +LLR L G + VGG +R DVRI++AT+++L++ + +G FREDL+YRLN Sbjct: 242 DMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLN 301 Query: 366 VLSLEVPPLRERGHDILLLARHFMQQACAQIQRPVCRLAPGTYPALLNNRWPGNVRQLQN 425 V+ L +PPLR+R DI L RHF+QQA + V R + + WPGNVR+L+N Sbjct: 302 VVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMKAHPWPGNVRELEN 360 Query: 426 VIFRAAAICESSLVDIGDLEIAGTAVARQND----------------------------- 456 ++ R A+ ++ +E + + Sbjct: 361 LVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFG 420 Query: 457 ---GEVGSLEEAVEGFEKALLEKLYVSYPSTRQLAAR-LQTSHTAIAHRLRKYGI 507 G + + E L+ + + AA L + + ++R+ G+ Sbjct: 421 DALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 33.9 bits (78), Expect = 0.002 Identities = 17/36 (47%), Positives = 21/36 (58%) Query: 520 YTRNAARTIGLERRIGSLEPGKQADFIVLDRDVFEV 555 YT N A GL IGSLE GK+AD ++ + F V Sbjct: 409 YTINPAIAHGLSHEIGSLEVGKRADLVLWNPAFFGV 444 Score = 30.9 bits (70), Expect = 0.018 Identities = 23/79 (29%), Positives = 37/79 (46%), Gaps = 10/79 (12%) Query: 19 HALGAADLLVVNARIFTANPQQPFAEALAVEDGRILAVGDEAGLRALADGDSQVVDLG-- 76 GA D ++ NA I + + ++DGRI A+G +AG + G + +V G Sbjct: 63 REGGAVDTVITNALIL--DHWGIVKADIGLKDGRIAAIG-KAGNPDMQPGVTIIVGPGTE 119 Query: 77 -----GKRLMPGLIDTHSH 90 GK + G +D+H H Sbjct: 120 VIAGEGKIVTAGGMDSHIH 138
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 36.4 bits (84), Expect = 8e-05 Identities = 32/177 (18%), Positives = 59/177 (33%), Gaps = 15/177 (8%) Query: 137 RPGSDLHAYPWLNPTNLGRMADVLASDLERLAPGAAATIQANLATLKKQL--LEATASNE 194 + D HA WLN N A +A L P + NL +L L+ + ++ Sbjct: 133 KGKEDPHA--WLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDK 190 Query: 195 TRLAKADNLSVISLSERLGYLLAGLNLDPLDV-EIQADDGWTETNIQAFAEELKSEDIAL 253 A+ +++ Y + + EI ++ T I+ E+L+ + Sbjct: 191 FNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPS 250 Query: 254 VLHHRQPPKPLADAIA-ASGARL---VVVDT--EAADPVAGLESDMK----AIVEGL 300 + ++ + + + D+ E S MK I EGL Sbjct: 251 LFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNLDKIAEGL 307
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 166 bits (423), Expect = 9e-52 Identities = 71/309 (22%), Positives = 130/309 (42%), Gaps = 23/309 (7%) Query: 21 ALLAALLLALLAPLAQA------EDGKRLRIGITLHPYYSYVSNIVGDKAEVVPLIPAGF 74 L L L+ + +A A G++L++ T NI GDK ++ ++P G Sbjct: 5 GTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQ 64 Query: 75 NPHAYEPRAEDIKRIGTLDVVVLNGVGHD--------DFAERMIASSEKPGIPVIEANAK 126 +PH YEP ED+K+ D++ NG+ + E + K V + Sbjct: 65 DPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDV 124 Query: 127 VPLLAATGMAARGAGKVVNPHTFLSISASITQVNTIARELGKLDPANAKAYTRNARAYAK 186 + L +PH +L++ I IA++L DP N + Y +N + Y Sbjct: 125 IYLEGQ------NEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTD 178 Query: 187 RLRALRADALARLNKAPAADFRVATIHGAYDYLLREFGLEVTAVVEPAHGIEPSPSQLKK 246 +L L ++ + NK PA + T GA+ Y + +G+ + E E +P Q+K Sbjct: 179 KLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKT 238 Query: 247 TIDQLKALDVKVIFSEIDFPSTYVETIQRESGVKLY-SLSHISYGDY--SAGKYEEEMAR 303 +++L+ V +F E ++T+ +++ + +Y + S + Y M Sbjct: 239 LVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKY 298 Query: 304 NLDTVVRAI 312 NLD + + Sbjct: 299 NLDKIAEGL 307
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 42.7 bits (100), Expect = 3e-05 Identities = 26/104 (25%), Positives = 42/104 (40%), Gaps = 9/104 (8%) Query: 4007 KIDRKALPKPDAGAQTQAYAPPQTEA-EKDLARLWREVLGVERVGLHDNFFELGGDSILA 4065 ++ A T E K +A L +E E + ++ + G DS+ Sbjct: 209 QLQNAPADVQKTSANTGKKNVFTCENIRKQIAELLQE--TPEDITDQEDLLDRGLDSVRI 266 Query: 4066 VQLVGRIRLWRAPGLEISLRDLMHKPTIAA---LLESRSHAGSP 4106 + LV + WR G E++ +L +PTI LL +RS P Sbjct: 267 MTLVEQ---WRREGAEVTFVELAERPTIEEWQKLLTTRSQQVLP 307
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.025 Identities = 10/23 (43%), Positives = 14/23 (60%) Query: 37 VVSILGPSGVGKSSLLRVLAGLQ 59 V + G G+GKS+L+ L GL Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLD 620
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.0 bits (109), Expect = 2e-07 Identities = 36/170 (21%), Positives = 73/170 (42%), Gaps = 7/170 (4%) Query: 35 FVAILSETLPAGLLPQIGAGLAVSEALAGQLVSVYALGSLLAALPAASLTQGWRRRRVLL 94 F ++L+E + LP I A + + + L + L+ +R+LL Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 95 LALLIFFVCNSLTAVS-SDYRLTLLARFGSGVAAGLAWGLLAGYARRLVPPEQQGRALAV 153 ++I + + V S + L ++ARF G A L+ R +P E +G+A Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAF-- 141 Query: 154 AMLGAPLALSLGVPLGTWLGGLLG--WRWAFGLLSLTALLLVGWVLRSVP 201 ++G+ +++G +G +GG++ W++ LL ++ L + Sbjct: 142 GLIGS--IVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLL 189
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.8 bits (204), Expect = 2e-21 Identities = 59/202 (29%), Positives = 93/202 (46%), Gaps = 8/202 (3%) Query: 7 RFAVVTGASSGIGLKLTETLLGHGATVLAM---ARRERPPESLHAHSGKRLHWLAGDVTR 63 + A +TGA+ GIG + TL GA + A+ + S + DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 64 ERDLDALASR-AASIGPVDYLVPNAGIAQLA--DGLDSLAFEQQWRVNGAGALNTFSVLS 120 +D + +R +GP+D LV AG+ + L +E + VN G N +S Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 121 RQ--TSKPTSVVFIGTFLSQVTFPGLAAYIASKAALIAQARTLAVEWAEKGVRINLVSPG 178 + + S+V +G+ + V +AAY +SKAA + + L +E AE +R N+VSPG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 179 PTATPIWASLGLSDAQAESVTR 200 T T + SL + AE V + Sbjct: 189 STETDMQWSLWADENGAEQVIK 210
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 31.7 bits (72), Expect = 0.006 Identities = 21/113 (18%), Positives = 36/113 (31%), Gaps = 9/113 (7%) Query: 258 RAAIGSPGTGVNGFRRSHLEALTTQRLMGRLAGAPAVATIDQVRMVSLMTQDDRAARQFV 317 R P + R +E + + A A + + + ++ R Sbjct: 364 RLTALYPQDVI---TREIIE-NELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 318 LSTLGRLATEPSVL-----QRSLHAFLANGCNVTQTAEALGTHRNTLLRRLER 365 L VL L A A N + A+ LG +RNTL +++ Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 73.3 bits (180), Expect = 2e-15 Identities = 33/209 (15%), Positives = 80/209 (38%), Gaps = 9/209 (4%) Query: 558 TTINRVVDAAKAFRSEYPMSGISIRLASGNAGVLAAINEEVEKSETPMLLYVYAAIALLV 617 T + + +P G+ + + EV K+ L + L++ Sbjct: 301 DTAKAIKAKLAELQPFFP-QGMKVLYPYDTTPFVQLSIHEVVKT----LFEAIMLVFLVM 355 Query: 618 FVVYRDLRAVLVCCLPLTIGTFIGYWFMKELQIGLTIATLPVMVLAVGIGVDYAFYIYNR 677 ++ +++RA L+ + + + + + + T+ MVLA+G+ VD A + Sbjct: 356 YLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVEN 415 Query: 678 LQLHLAHGQTITK-AVEYALLEVGVATIFTAITLAVGVATWAF---SELKFQADMGKLLA 733 ++ + + K A E ++ ++ A + A+ L+ AF S + Sbjct: 416 VERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIV 475 Query: 734 FMFVVNMVMAMTVLPAFAVWLERAFPRKR 762 +++++A+ + PA L + + Sbjct: 476 SAMALSVLVALILTPALCATLLKPVSAEH 504 Score = 41.0 bits (96), Expect = 2e-05 Identities = 37/216 (17%), Positives = 75/216 (34%), Gaps = 11/216 (5%) Query: 205 IADGASAVLEFCLLALLLTAGAVYWYCHSLRFTLLALVCSLASLVWQFGSLRLLGYGLDP 264 + V++ A++L +Y + ++R TL+ + L+ F L GY ++ Sbjct: 333 VQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT 392 Query: 265 LAVLVPFLVFAIGVSHGVQQINFIVREIAIGKS----AEEAARSSFTGLLVPGTLALVTA 320 L + L + V + + + R + K A E + S G LV + L Sbjct: 393 LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 321 LVSFVTLLLIPIPMVRELAITASLGVAYKIVTNLVMLPLMASLLRVDDKYAAAQEVSRQR 380 + + R+ +IT +A ++ L++ P + + L K +A+ + Sbjct: 453 FIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLL---KPVSAEHHENKG 509 Query: 381 R-SRWL-RGLARLAE--PRKAQWVLGAALAVFLAAI 412 W +LG+ L Sbjct: 510 GFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYA 545 Score = 35.6 bits (82), Expect = 0.001 Identities = 30/175 (17%), Positives = 60/175 (34%), Gaps = 18/175 (10%) Query: 597 EVEKSETPMLLYVYAAIALLVFVV----YRDLRAVLVCCL--PLT-IGTFIGYWFMKELQ 649 E+ + A ++VF+ Y + L PL +G + Sbjct: 863 YQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLF---N 919 Query: 650 IGLTIATLPVMVLAVGIGVDYAFYIYNRL-QLHLAHGQTITKAVEYALLEVGVATIFTAI 708 + + ++ +G+ A I L G+ + +A A+ + T++ Sbjct: 920 QKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSL 979 Query: 709 TLAVGV-----ATWAFSELKFQADMGKLLAFMFVVNMVMAMTVLPAFAVWLERAF 758 +GV + A S Q +G + V ++A+ +P F V + R F Sbjct: 980 AFILGVLPLAISNGAGSGA--QNAVGIGVMGGMVSATLLAIFFVPVFFVVIRRCF 1032
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 50.4 bits (120), Expect = 5e-10 Identities = 30/190 (15%), Positives = 68/190 (35%), Gaps = 11/190 (5%) Query: 3 RVGAEVRRQDFIEAAVKVIAEYGVANATTRRIAAAANSPLASLHYVFHTKDELFDAVYES 62 + A+ RQ ++ A+++ ++ GV++ + IA AA ++++ F K +LF ++E Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 63 LIDKPQQSLLHVTA--GATAADSVAEILRQLVGWFTTHPE-----LATTQFELFFWNLRN 115 + L A + EIL ++ T F + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 116 NPAMASKIYTDSVEATKQAIEQV--AGSVLDQEALATVSRLLINLFDGLLLAWSAHGDQE 173 + +S + +Q ++ A + + ++ GL+ W + Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF--APQ 183 Query: 174 RLNAETEAAC 183 + + EA Sbjct: 184 SFDLKKEARD 193
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 26.5 bits (58), Expect = 0.027 Identities = 14/46 (30%), Positives = 22/46 (47%), Gaps = 1/46 (2%) Query: 50 VIARRLAQGSNMTFGVAAGVFLFVFFCALSALYVYRANGEFDRLTQ 95 +IA+R AQG + + AAG+ A+S L +F R + Sbjct: 291 IIAQRAAQGLSTS-AAAAGLIASAVTLAISPLSFLSIADKFKRANK 335
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 112 bits (282), Expect = 3e-32 Identities = 71/253 (28%), Positives = 123/253 (48%), Gaps = 14/253 (5%) Query: 10 ALDGRRALVTGASSGLGRHFAMTLAAAGAEVVVTARRQAPLQALVEAIEVAGGRAQAFAL 69 ++G+ A +TGA+ G+G A TLA+ GA + L+ +V +++ A+AF Sbjct: 5 GIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPA 64 Query: 70 DV----TCREDICRVLDAAGPLDVLVNNAGVSDSQPLLACDDQSWDRVLDTNLKGAWAVA 125 DV E R+ GP+D+LVN AGV + + D+ W+ N G + + Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNAS 124 Query: 126 QESARRMVAAGKGGSLINVTSILASRVAGAVGPYLAAKAGLAHLTRAMALELARHGIRVN 185 + ++ M+ + GS++ V S A ++ Y ++KA T+ + LELA + IR N Sbjct: 125 RSVSKYMMDR-RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCN 183 Query: 186 ALAPGYVMTDLNEAFLASEAGDKLRSR---------IPSRRFSVPADLDGALLLLASDAG 236 ++PG TD+ + A E G + + IP ++ + P+D+ A+L L S Sbjct: 184 IVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQA 243 Query: 237 RAMSGAEIVVDGG 249 ++ + VDGG Sbjct: 244 GHITMHNLCVDGG 256
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 27.9 bits (62), Expect = 0.024 Identities = 15/61 (24%), Positives = 24/61 (39%), Gaps = 6/61 (9%) Query: 34 QISAELSAVAGSGKVMEGGFVVYSPAAKLALLGLDPNWLERFNLTSVEVAEAMARAALQR 93 + LS + G G V G A + LD + L ++ LT V+V + Q Sbjct: 161 NVKDTLSRLNGVGDVQLFG------AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQI 214 Query: 94 S 94 + Sbjct: 215 A 215
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 34.4 bits (79), Expect = 2e-04 Identities = 15/80 (18%), Positives = 32/80 (40%), Gaps = 2/80 (2%) Query: 58 VLVLEEHAEQLWRIEEFLLDRGYAVLSAASRDEALDHLASDAVIDLFLLSEQLEGSLSGS 117 +LV ++ A + + L GY V ++ +A+ DL + + + Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDG-DLVVTDVVMPD-ENAF 63 Query: 118 MLIETSLPVRPRMRVILLSD 137 L+ RP + V+++S Sbjct: 64 DLLPRIKKARPDLPVLVMSA 83
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 772 bits (1996), Expect = 0.0 Identities = 272/881 (30%), Positives = 412/881 (46%), Gaps = 50/881 (5%) Query: 7 RRCRTGTALMAGGMALAASAFGHAQPGYEFDDRLLLGSSLGGGDLSRFNQDGRIDPGRYH 66 R + A AA A + F+ R L DLSRF + PG Y Sbjct: 21 HRLAGFFVRLFVACAFAAQA-PLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYR 79 Query: 67 VDVYLNERFASRSEVSFRANPASGAVEPCLDEDFLRQRLGAKPGDDPRKSGDGRHCAFLD 126 VD+YLN + + +V+F + + PCL L C L Sbjct: 80 VDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPLT 139 Query: 127 ARLPGSRFSLDVARLRLDLSVPQALLDLKPRGYVSPEEWDAGDSMGFVNYDTNLYRSEYR 186 + + + LDV + RL+L++PQA + + RGY+ PE WD G + G +NY+ + + R Sbjct: 140 SMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNR 199 Query: 187 GGESGRSDYAYVGLNSGINLGLWRLRHQSNYTYSRYNGQA--RRKWNSIRTYAQRALPAW 244 G G S YAY+ L SG+N+G WRLR + ++Y+ + + + KW I T+ +R + Sbjct: 200 IG--GNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPL 257 Query: 245 RSELTAGESYTAGNLLGSIGYRGLSLATDDRMLPESLRRYAPQVRGTAATAARVVISQNG 304 RS LT G+ YT G++ I +RG LA+DD MLP+S R +AP + G A A+V I QNG Sbjct: 258 RSRLTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNG 317 Query: 305 RKIREVNVAPGPFVIDDLYDSAYAGDLDVQVFEADGSVSSFSVPFASVPESMRPGLSRYS 364 I V PGPF I+D+Y + +GDL V + EADGS F+VP++SVP R G +RYS Sbjct: 318 YDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYS 377 Query: 365 FTLGQARQYGDGDD--LFADFTYQRGMSNALTANLGLRVADDYLA-MLGGGVLATRFGAF 421 T G+ R + F T G+ T G ++AD Y A G G GA Sbjct: 378 ITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 422 GLNSTYSSARVEDGARKQGWRIGLDYSRTFQPTGTTLTLAGYRYSTEGYRELGDVLGSRD 481 ++ T +++ + D ++ G + Y+++ +GT + L GYRYST GY D SR Sbjct: 438 SVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRM 497 Query: 482 ALRHGDTWD-------------SGSYKQRNQFNLLVSQALGGYGNLYLSGSSSDFYDGKS 528 + +T D + +Y +R + L V+Q LG LYLSGS ++ + Sbjct: 498 NGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSN 557 Query: 529 RDTQLQFGYSNTWGQLSYNLAWSRQTTTYYQEQGDQDPGVELLRRDRRSGQRNDTLTLSV 588 D Q Q G + + +++ L++S ++ R+ L L+V Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLT-------------------KNAWQKGRDQMLALNV 598 Query: 589 SMPLGSSSRAPTLSA-----MATRRSGDSRGG-SLQTGLNGTLGDERTWSYALSA---NR 639 ++P R+ + S + S D G + G+ GTL ++ SY++ Sbjct: 599 NIPFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGG 658 Query: 640 DSEVADTTWNGTLQKQAALATVNAGYAQGDRYRQYSGGIRGALVAHRDGLTLGPSVGDTF 699 + +T TL + N GY+ D +Q G+ G ++AH +G+TLG + DT Sbjct: 659 GDGNSGSTGYATLNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTV 718 Query: 700 ALVEAKGASGAAIRGGQGARIDGNGYALAPSLSPYRYNPISLDPVGIDPDAELLETERKV 759 LV+A GA A + G R D GYA+ P + YR N ++LD + + +L V Sbjct: 719 VLVKAPGAKDAKVENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANV 778 Query: 760 APYAGASVRVTFRTLTGHPLLIQARREDGSVLPLGAVVVDDGGAAIGMVGQGGQVYARAE 819 P GA VR F+ G LL+ + LP GA+V + + G+V GQVY Sbjct: 779 VPTRGAIVRAEFKARVGIKLLMTLTH-NNKPLPFGAMVTSESSQSSGIVADNGQVYLSGM 837 Query: 820 NQRGRLLVQWGTARKERCELPYDLAGVSRDQALIRLRGTCR 860 G++ V+WG C Y L S+ Q L +L CR Sbjct: 838 PLAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQLSAECR 878
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.3 bits (70), Expect = 0.006 Identities = 15/36 (41%), Positives = 20/36 (55%), Gaps = 4/36 (11%) Query: 128 PQADPDAEGQPPASAAVRTDAPAAPRQRTQRPRRTR 163 P A+PD +GQP R D+PA P + R R+ R Sbjct: 361 PDANPDTDGQP----GTRPDSPAVPDRPNGRHRKER 392
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 39.1 bits (91), Expect = 3e-05 Identities = 37/180 (20%), Positives = 82/180 (45%), Gaps = 6/180 (3%) Query: 29 FWSCKIGYGLDGMDTQMLSFVIPTLIALWGIGTGEAGFIHTMTLLASAAGGWIAGILSDR 88 W C + + ++ +L+ +P + + +++T +L + G + G LSD+ Sbjct: 17 IWLCILSF-FSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 89 IGRVLTLQLTVLWFAFFTFLCGLAQNYEQLLV-ARTLMGFGFGGEWTAGAVLIGEVIKAR 147 +G L ++ F + + + ++ LL+ AR + G G V++ I Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 148 DRGKAVGLVQSGWAIGWGLTAILYSLMFSLLPPEEAWRALFMLGLLPALFVLVVRRLVKE 207 +RGKA GL+ S A+G G+ + ++ + W L ++ ++ + V + +L+K+ Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHYI----HWSYLLLIPMITIITVPFLMKLLKK 191
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.5 bits (211), Expect = 5e-22 Identities = 55/188 (29%), Positives = 85/188 (45%), Gaps = 9/188 (4%) Query: 2 QNILISGAASGIGAASARLFHRRGWRVGLLDIDAEALRGLAAQLPGAWHRA----VDVSE 57 + I+GAA GIG A AR +G + +D + E L + + L A DV + Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 58 PDAVGEALAQFCAD-GRLRLLFNCAGVLRFGRFEEVALEDHARLLAINLQGVLNCCHAAF 116 A+ E A+ + G + +L N AGVLR G ++ E+ ++N GV N + Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 117 PFLRATPQAQVLNMGSASGLYGVPE--MAVYSASKFAVRGLTEALELEWRRHGIRVADLM 174 ++ ++ +GS GVP MA Y++SK A T+ L LE + IR + Sbjct: 129 KYMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 175 PPFVRTPM 182 P T M Sbjct: 187 PGSTETDM 194
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 54.4 bits (131), Expect = 3e-10 Identities = 84/365 (23%), Positives = 139/365 (38%), Gaps = 20/365 (5%) Query: 23 VGTVELVVAGVLDELAASFAVSQGRAGLLMSLYALVYALLGPLLVYLSAGIERRRLLAGA 82 +G + V+ G+L +L S V G+L++LYAL+ P+L LS RR +L + Sbjct: 21 IGLIMPVLPGLLRDLVHSNDV-TAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVS 79 Query: 83 LLAFIGANLASAAAPSFALLLASRLLVAASASVIVVVAITLAVAIVAPERRGRAIGLVFA 142 L A AP +L R++ + + V +A I + R R G + A Sbjct: 80 LAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIA-DITDGDERARHFGFMSA 138 Query: 143 GIVASLVLGVPLGTLIGEFWGWRSLFLLLAGVALLGLPLLLRLL---------PAIPGAP 193 +V G LG L+G F + F A + L LL P A Sbjct: 139 CFGFGMVAGPVLGGLMGGF-SPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREAL 197 Query: 194 GIAPAEQLRALARGRVPFAHLASLLQMTGQFTVYTYIVPFLVGSMALDKPTISLVLLVYG 253 + + + ++Q+ GQ +++ F D TI + L +G Sbjct: 198 NPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVI-FGEDRFHWDATTIGISLAAFG 256 Query: 254 GGGILG-ALLGGRAADRWPGPATFVAFLLLHALALVLLPFATGGLPLLLGAVVFWCVFNM 312 L A++ G A R + ++ +LL FAT G V+ Sbjct: 257 ILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLL--ASGG 314 Query: 313 APGPAIQKYLVELSPDTAAIQISLNTSAIQLGVALGAFIGAILVDQVAVRALPWW-GAAL 371 PA+Q L + Q+ + +A+ +L + +G +L + ++ W G A Sbjct: 315 IGMPALQAMLSRQVDEERQGQLQGSLAALT---SLTSIVGPLLFTAIYAASITTWNGWAW 371 Query: 372 ILGAA 376 I GAA Sbjct: 372 IAGAA 376
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 28.6 bits (64), Expect = 0.048 Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 3/137 (2%) Query: 70 VTLLGLAVALSSPLKGWLVDRWGARALVLPLTAALALCLASLALARSGWQLYLLFALLGL 129 + L L +P+ G L DR+G R ++L A A+ A +A A W LY+ + G+ Sbjct: 49 LALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGI 108 Query: 130 L-TPGNIPYARILGGWFERRRGAAYGILGLGFGVGGPLALYLGSACIDAFGWRATFLVYG 188 G + A I R +G + FG G LG F A F Sbjct: 109 TGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAA 167 Query: 189 LLEGLLALPLLYALFRE 205 L GL L L E Sbjct: 168 ALNGLNFL-TGCFLLPE 183
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 42.2 bits (99), Expect = 7e-07 Identities = 16/59 (27%), Positives = 27/59 (45%) Query: 68 LARLYSIAIDPRARGIGLGQKLLEAAEQAARDNDRAYMRLEVRPDNRGAIALYERNGYR 126 A + IA+ R G+G LL A + A++N + LE + N A Y ++ + Sbjct: 89 YALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.6 bits (71), Expect = 0.012 Identities = 40/248 (16%), Positives = 71/248 (28%), Gaps = 9/248 (3%) Query: 266 DQNNVQALRSANGEQSNLYTTIATLKRQYRDLELAINPDGGSPNSPISEELQQQTAIVTR 325 + ++ ++ TLK + DL N ++EEL + + Sbjct: 48 QTDTLEKVQERAD---KFEIENNTLKLKNSDLSFNNK-ALKDHNDELTEELSNAKEKLRK 103 Query: 326 LVGDYETSLSNLTIFNSTLSTHIQLKTQTQEELTRNKTTKKLREYGASKHLHAASDSCPT 385 S + + + + T + K E + +D Sbjct: 104 NDKSLSEKASKIQELEARKADLEKALEGAMNFSTADSAKIKTLEAEKAALAARKADL--- 160 Query: 386 CHQHIEDS-LISINLTGSAMDIETNIHYLESQAKMLAKQEAGLELKIRDAEIICQNFSAQ 444 + +E + S + +E LE++ L K G + A+ Sbjct: 161 -EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAE 219 Query: 445 LEKERSVLSSLRKDAAKGNIVSQAAVKKQVLLEWEIERLEEFSDKLEDALADMAKLATAF 504 + + L K S A K LE E LE +LE AL +TA Sbjct: 220 KAALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTAD 279 Query: 505 KANQDKRK 512 A + Sbjct: 280 SAKIKTLE 287
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 99.9 bits (249), Expect = 2e-25 Identities = 85/335 (25%), Positives = 125/335 (37%), Gaps = 37/335 (11%) Query: 49 GVAVTVGGIAWMLAARPWGIASDRHGRRRILLGGLAGFALSYGSLCLFIVLALHWTLPTL 108 G+ + + + A G SDR GRR +LL LAG A+ Y + Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDY----------------AI 89 Query: 109 FAFAG---IVLLRGLAGGFYAAVPACTAALVADHVEAQRRAAALAGLGAASAIGMVIGPG 165 A A ++ + + G A A A +AD + RA + A GMV GP Sbjct: 90 MATAPFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPV 149 Query: 166 LAGLLATHGLVLPLLVTGALPLVALLALWRWLP----------REERRQPNRGAALAIGD 215 L GL+ P AL + L LP R E P A G Sbjct: 150 LGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGM 209 Query: 216 RRLRRPLAVGFVAMFSVTVAQITVGFFALDRLRLDSADAARVAGIALTAVGVALILAQLL 275 + +AV F+ V F DR D+ GI+L A G+ LAQ + Sbjct: 210 TVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATT----IGISLAAFGILHSLAQAM 265 Query: 276 VRRL---DWPPPRLIRVGGLVAAIGFAAVCFADSPPLLWLAFFVAAAGMGWVFPAVSALN 332 + R + +G + G+ + FA + + + A+G G PA+ A+ Sbjct: 266 ITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG-GIGMPALQAML 324 Query: 333 ANAVRAEEQGAAAGTLVAVHGFGLISGPLLGALLH 367 + V E QG G+L A+ I GPLL ++ Sbjct: 325 SRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIY 359 Score = 37.1 bits (86), Expect = 1e-04 Identities = 36/140 (25%), Positives = 56/140 (40%), Gaps = 7/140 (5%) Query: 251 SADAARVAGIALTAVGVA-LILAQLLVRRLDWPPPRLIRVGGLV-AAIGFAAVCFADSPP 308 S D GI L + A +L D R + + L AA+ +A + A P Sbjct: 38 SNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATA---P 94 Query: 309 LLWLAFF--VAAAGMGWVFPAVSALNANAVRAEEQGAAAGTLVAVHGFGLISGPLLGALL 366 LW+ + + A G A A+ +E+ G + A GFG+++GP+LG L+ Sbjct: 95 FLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLM 154 Query: 367 HQLDNRAPYALVGLLLALAA 386 AP+ L L Sbjct: 155 GGFSPHAPFFAAAALNGLNF 174
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 348 bits (895), Expect = e-124 Identities = 101/207 (48%), Positives = 135/207 (65%), Gaps = 2/207 (0%) Query: 3 GIPEITAYPLPTAQQLPANLARWSLESRRAVLLVHDMQRYFLRPLPESLRA--GLVANAA 60 IP I Y +PTA +P N W + RAVLL+HDMQ YF+ L AN Sbjct: 2 AIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANIR 61 Query: 61 RLRRWCVEQGVQIAYTAQPGSMTEEQRGLLKDFWGPGMRASPADREVVEELAPGPDDWLL 120 +L+ CV+ G+ + YTAQPGS + R LL DFWGPG+ + P + +++ ELAP DD +L Sbjct: 62 KLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVL 121 Query: 121 TKWRYSAFFHSDLLQRMRAAGRDQLVLCGVYAHVGVLISTVDAYSNDIQPFLVADAIADF 180 TKWRYSAF ++LL+ MR GRDQL++ G+YAH+G L++ +A+ DI+ F V DA+ADF Sbjct: 122 TKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADF 181 Query: 181 SEAHHRMALEYAASRCAMVVTTDEVLE 207 S H+MALEYAA RCA V TD +L+ Sbjct: 182 SLEKHQMALEYAAGRCAFTVMTDSLLD 208
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 296 bits (759), Expect = 9e-99 Identities = 83/416 (19%), Positives = 179/416 (43%), Gaps = 53/416 (12%) Query: 24 PVYRPLLWTLLGCVLLFIGWAAWAQLDEVTRGDGRVVPFSRIQKIQSLEGGILDRLLVKE 83 R + + ++G +++ + Q++ V +G++ R ++I+ +E I+ ++VKE Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 84 GDLVEVGQPLVRLDETRFLTNFQESANQASVLRAAIARLDAEVLGKKSIEFPPDVDPEGP 143 G+ V G L++L + ++ + R R + + P P+ P Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 144 LARSERELFKSRRDKLVE-----------------------------GTQAIQRQIHLAQ 174 ++ E R L++ + + + Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Query: 175 SQLDLVRPLVAKRAVSQMEALK-------LSQDIATLSGKLTELKS-------------- 213 S+LD L+ K+A+++ L+ ++ +L +++S Sbjct: 235 SRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQ 294 Query: 214 TYFQDAYTERAQRKADLSALEPIVQQRQDQLRRTEILSPVRGRVNTVLINTRGGVIQPGE 273 + + + Q ++ L + + +++ + + I +PV +V + ++T GGV+ E Sbjct: 295 LFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354 Query: 274 PIMEVIPVEERLLVEAKIKPRDVAFLVPGMPAKVKITAYDYTIYGDLKGTLEQISADTIE 333 +M ++P ++ L V A ++ +D+ F+ G A +K+ A+ YT YG L G ++ I+ D IE Sbjct: 355 TLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIE 414 Query: 334 EDTPHGKESYYQVLIKTDGSQLKRGEEVLPIIPGMVAEVDILSGKRSVLNYLLRPL 389 + + V+I + + L G + +P+ GM +I +G RSV++YLL PL Sbjct: 415 DQRLG---LVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPL 467
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.0 bits (70), Expect = 0.009 Identities = 24/162 (14%), Positives = 49/162 (30%), Gaps = 18/162 (11%) Query: 250 DANVAEAEVREAKASLLPQLNLEASALRREIGGHPESDSVVSLRFRMDTFQGLSNFRRPT 309 A AEA+ + ++SLL R +I S+ L + Sbjct: 128 TALGAEADTLKTQSSLL---QARLEQTRYQI-------LSRSIELNKLPELKLPDEPYFQ 177 Query: 310 AAQQRLESAKWSADAMQRD-IRRQLQNLFDNGDTLRWREQSLTQQVTESEQVGELYREQ- 367 + S Q + Q N D R ++ ++ E + + + + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 368 ------FEVGRRDVIDLLNVQRERFEAERQLINLRIERKRIE 403 +L + + EA +L + + ++IE Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 48.4 bits (115), Expect = 3e-07 Identities = 35/163 (21%), Positives = 65/163 (39%), Gaps = 8/163 (4%) Query: 2519 TDSNGNDSAAYGITLTPNGLSLNIGQI-DVNGTSGDDVLSGANGSSEHINGGDGSDLIFN 2577 D+ G D+ + ++LN G DV G G+ ++ E+ GG G+D++ Sbjct: 296 WDAGGTDTFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTI-ENAIGGSGNDILVG 354 Query: 2578 VGTGDHVVAGNGNDTIQITATDFVSIDGGAGFDTLVLANGIDLDYNAVGVGT--LSNLER 2635 + + G GND + A ++ GGAG DT V +G D A +++ Sbjct: 355 NSADNILQGGAGNDVLYGGAGA-DTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDK 413 Query: 2636 IDLGKGDSGSVLTLTAAEVDAITDANNTLQITGENNDTLNVVG 2678 IDL + + D T + + + +++ + Sbjct: 414 IDL---SAFRNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLW 453
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 591 bits (1524), Expect = 0.0 Identities = 196/591 (33%), Positives = 324/591 (54%), Gaps = 26/591 (4%) Query: 44 EQWTINMKDAEIGDFIEQVSSISGQTFVVDPRVKGRVTVVSQARLSLAEVYQLFLSVLAT 103 E+++ + K +I +FI VS +T ++DP V+G +TV S L+ + YQ FLSVL Sbjct: 28 EEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLDV 87 Query: 104 HGYAVLPQGDQA-RIVPNMEARQDAAQKTVRDGPG---SLETRVVQAQQTSVAELIPMIR 159 +G+AV+ + ++V + +A+ A PG + TRVV + +L P++R Sbjct: 88 YGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLR 147 Query: 160 PLVPAHGHLAAV--PSANALIVSDRRSNIERIEAIVRSLDRAGEHDYSIYDMRHAWVAEI 217 L G + V +N L+++ R + I+R+ IV +D AG+ + A A++ Sbjct: 148 QLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVPLSWASAADV 207 Query: 218 AEV---LDRSVTPAAGKSAATVQVLADSRSNRLVLLGPPQARARLLRLAQSLDVPSSRSA 274 ++ L++ + +A + V+AD R+N +++ G P +R R++ + + LD + Sbjct: 208 VKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQQATQG 267 Query: 275 NSRVIRLRHGDAKTLAATLGEIGESLHGER-GQDGRGSGKRGLLVRADESLNALVILADP 333 N++VI L++ A L L I ++ E+ + + ++++A NAL++ A P Sbjct: 268 NTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTNALIVTAAP 327 Query: 334 EDVGLLEDIVRQLDVPRAQLLVEAAIVELSGEIGDALGVQWALRSGHVAGGAGFADSGLS 393 + + LE ++ QLD+ R Q+LVEA I E+ G LG+QWA AG F +SGL Sbjct: 328 DVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA---NKNAGMTQFTNSGLP 384 Query: 394 IGTLLGAL----QAGKPPAELP------DGAIVGLGSRDFGALVTALSRNSRSNLLSTPS 443 I T + + G + L +G G ++ L+TALS ++++++L+TPS Sbjct: 385 ISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTALSSSTKNDILATPS 444 Query: 444 LLTLDNQKAEILVGQNVPFQTGSYTTSASGSSNPFTTVERKDIGVTLKVTPHIGEDRMLR 503 ++TLDN +A VGQ VP TGS TTS N F TVERK +G+ LKV P I E + Sbjct: 445 IVTLDNMEATFNVGQEVPVLTGSQTTS---GDNIFNTVERKTVGIKLKVKPQINEGDSVL 501 Query: 504 LEIEQEISSIAPTATLAAKAVDLVTNKRSIKSTVLADDGQVIVLGGLIQDDLQRSDSRVP 563 LEIEQE+SS+A A+ + + N R++ + VL G+ +V+GGL+ + + +VP Sbjct: 502 LEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGLLDKSVSDTADKVP 561 Query: 564 LLGDIPGVGRLFRSSRETRVKRNLMVFLRPSIVRDAAGLERISHGRYRSIQ 614 LLGDIP +G LFRS+ + KRNLM+F+RP+++RD + S G+Y + Sbjct: 562 LLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQYTAFN 612
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.7 bits (165), Expect = 5e-16 Identities = 25/152 (16%), Positives = 56/152 (36%), Gaps = 8/152 (5%) Query: 5 RQRNLQLILDAACEVFADCGFSAARLSDVAERAGVAKANVLYYYRSKAQLYEAVLDSIVE 64 Q Q ILD A +F+ G S+ L ++A+ AGV + + ++++ K+ L+ + + Sbjct: 9 AQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSES 68 Query: 65 PLLEASRPFAGDQP--PAEALRAYVDNKMRIGAERPHAARVFSCEIMRGAPRMPAPLLER 122 + E + P P LR + + + + + ++++ Sbjct: 69 NIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 123 LDAQAERN-----AERIRQWIDEG-LLAPLDP 148 + ++ I+ L A L Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMT 160
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 62.8 bits (152), Expect = 9e-14 Identities = 61/262 (23%), Positives = 99/262 (37%), Gaps = 23/262 (8%) Query: 4 LTGKRALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCF 63 + GK A I G A I +A + +GA +A N + +V E F Sbjct: 6 IEGKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE-AF 62 Query: 64 PCDVADDSQIEAVFAALGKHWDGLDIIVHSVGF---APGDQL-DGDFTAVTTREGFRIAH 119 P DV D + I+ + A + + +DI+V+ G L D ++ A + + Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGV-- 120 Query: 120 DISAYSFIALAKAGREMMKGRNGSLLTLSYLGAERTMPNYNVMGMAKASLEAGVRYLAGS 179 F A + MM R+GS++T+ A + +KA+ + L Sbjct: 121 ------FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLE 174 Query: 180 LGAEGTRVNAVSAGPIRTLAASGI--------KSFRKMLAANERQTPLRRNVTIEEVGNA 231 L R N VS G T + + + L + PL++ ++ +A Sbjct: 175 LAEYNIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADA 234 Query: 232 GAFLCSDLASGISGEILYVDGG 253 FL S A I+ L VDGG Sbjct: 235 VLFLVSGQAGHITMHNLCVDGG 256
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 117 bits (296), Expect = 1e-38 Identities = 49/88 (55%), Positives = 64/88 (72%) Query: 2 NKSELIDAIAASADIPKAVAGRALDAVIESVTGALKAGDSVVLVGFGTFAVKERAARTGR 61 NK +LI +A + ++ K + A+DAV +V+ L G+ V L+GFG F V+ERAAR GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 62 NPQTGKPIKIAAAKIPGFKAGKALKDAV 89 NPQTG+ IKI A+K+P FKAGKALKDAV Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.2 bits (190), Expect = 2e-18 Identities = 31/132 (23%), Positives = 63/132 (47%), Gaps = 5/132 (3%) Query: 7 SKVLLVEDDQKLARLIASFLSQHGFEVRQVHRGDAAFAAFLDFKPQVVVLDLMLPGQNGL 66 + +L+ +DD + ++ LS+ G++VR + +VV D+++P +N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 67 QVCREIRRV-ANLPILILTAQEDDLDHILGLESGADDYVIKPIEPPVLLARLRALM---- 121 + I++ +LP+L+++AQ + I E GA DY+ KP + L+ + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 122 RRHAPLPASPES 133 RR + L + Sbjct: 124 RRPSKLEDDSQD 135
>PF06580#Sensor histidine kinase Length = 349 Score = 28.7 bits (64), Expect = 0.041 Identities = 20/123 (16%), Positives = 38/123 (30%), Gaps = 31/123 (25%) Query: 315 QIRIEPRFMARAVINLL-----RNAIRHAHS------RVEIALLDQGDSCQIRVNDDGPG 363 + +I P M V +L N I+H + ++ + + + V + G Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSL 302 Query: 364 IPADARQKIFEPFSRLDDSRDRSTGGFGLGLAIVR-RVAQWHGG-YAEALETPQGGASFR 421 + ++ G GL VR R+ +G L QG + Sbjct: 303 ALKNTKE------------------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAM 344 Query: 422 LTW 424 + Sbjct: 345 VLI 347
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 163 bits (415), Expect = 1e-49 Identities = 89/381 (23%), Positives = 140/381 (36%), Gaps = 79/381 (20%) Query: 1 MKLKNTLGVVIGSLVAASAMNAFAQGQNSVEIEAFGKRYFTD------SVRNMKNADLYG 54 MK K + + + A+ A + G + D + +N G Sbjct: 1 MK-KTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59 Query: 55 GSIGYFLTDDVELALSYGEY--HDVRGTYETGNKKVHGNLTSLDAIYHFGTPGVGLRPYV 112 GY + V + Y +G+ E G K G + Y T + + + Sbjct: 60 AFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPI-TDDLDIYTRL 118 Query: 113 SAGL----AHQNITNINSDSQ-------GRQQMTMANIGAGLKYYFTENFFAKASLDGQY 161 + N+ N D+ G + I L+Y +T N ++ Sbjct: 119 GGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTNNIGDAHTIG--- 175 Query: 162 GLEKRDNGHQGEWMAGLGVGFNFGGSKAAP----APEPVADVCSDSDNDGVCDNVDKCPD 217 + DNG M LGV + FG +AAP AP P +V + Sbjct: 176 --TRPDNG-----MLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKH-------------- 214 Query: 218 TPANVTVDANGCPAVAEVVRVQLDVKFDFDKSKVKENSYADIKNLADFMKQY--PSTSTT 275 ++ DV F+F+K+ +K A + L + S Sbjct: 215 ------------------FTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVV 256 Query: 276 VEGHTDSVGTDAYNQKLSERRANAVRDVLVNEYGVEGGRVNAVGYGESRPVADNATAEGR 335 V G+TD +G+DAYNQ LSERRA +V D L+++ G+ +++A G GES PV N + Sbjct: 257 VLGYTDRIGSDAYNQGLSERRAQSVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVK 315 Query: 336 ---------AINRRVEAEVEA 347 A +RRVE EV+ Sbjct: 316 QRAALIDCLAPDRRVEIEVKG 336
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 315 bits (808), Expect = e-100 Identities = 112/446 (25%), Positives = 190/446 (42%), Gaps = 68/446 (15%) Query: 360 RAIGQRI-GAGPVKVINDVSEMDKVQPGDVLVSDMTDPDWEPVMK-RASAIVTNRGGRTC 417 R + +R+ G ++ + + ++ D+T D + K T+ GGRT Sbjct: 132 RDVSKRVLGHLIGVETGSLATIA--EETVIIAEDLTPSDTAQLNKQFVKGFATDIGGRTS 189 Query: 418 HAAIIARELGIPAVFGCGNATQILQDGQGVTVSCAEG---------DTGFIFEGELGFDV 468 H+AI++R L IPAV G T+ +Q G V V EG + E F+ Sbjct: 190 HSAIMSRSLEIPAVVGTKEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEK 249 Query: 469 RKNSVDAMPDLP--------FKIMMNVGNPDRAFDFAQLPNEGVGLARLEFIINRMIGVH 520 +K + P ++ N+G P EG+GL R EF+ Sbjct: 250 QKQEWAKLVGEPSTTKDGAHVELAANIGTPKDVDGVLANGGEGIGLYRTEFLY------- 302 Query: 521 PKALLNFAGLPADIKESVEKRIAGYPDPVGFYVEKLVEGISTLAAAFWPKKVIVRLSDFK 580 ++ LP + E++ Y + + K V++R D Sbjct: 303 ----MDRDQLP-----TEEEQFEAYKE---------------VVQRMDGKPVVIRTLDIG 338 Query: 581 SNEYANLIGGKLYEPEEENPMLGFRGASRYISESFRDCFELECRALKKVRNEMGLTNVEI 640 ++ + L P+E NP LGFR + + +D F + RAL + N+++ Sbjct: 339 GDKELSY----LQLPKELNPFLGFRAIRLCLEK--QDIFRTQLRALLRAS---TYGNLKV 389 Query: 641 MVPFVRTLGEASQVVELLAGNGLKRGENG------LKVIMMCELPSNALLADEFLEFFDG 694 M P + TL E Q ++ K G ++V +M E+PS A+ A+ F + D Sbjct: 390 MFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIEVGIMVEIPSTAVAANLFAKEVDF 449 Query: 695 FSIGSNDLTQLTLGLDRDSGIVAHLFDERNPAVKKLLANAIAACNKAGKYIGICGQGPSD 754 FSIG+NDL Q T+ DR + V++L+ +PA+ +L+ I A + GK++G+CG+ D Sbjct: 450 FSIGTNDLIQYTMAADRMNERVSYLYQPYHPAILRLVDMVIKAAHSEGKWVGMCGEMAGD 509 Query: 755 HPDLARWLMEQGIESVSLNPDSVLDT 780 L+ G++ S++ S+L Sbjct: 510 -EVAIPLLLGLGLDEFSMSATSILPA 534
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 29.8 bits (66), Expect = 0.009 Identities = 27/102 (26%), Positives = 45/102 (44%), Gaps = 8/102 (7%) Query: 21 LRARDYQDYLSANRLVEAA--------RERAAEIEREAHEVYQEQKRLGWEAGLEEARLR 72 L RDYQ++L +L+ A +++A E E+EA E Q+ ++ E EE Sbjct: 117 LMTRDYQEFLKTKKLIVDAPDPKELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKN 176 Query: 73 QAGLIQETLLRCNRYYRQVDRQLGEVVLQAVRKVLRHYDAVE 114 +A L T N ++ L E++ Q L + +E Sbjct: 177 RANLENLTNAMSNPQNLSNNKNLSELIKQQRENELDQMERLE 218
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 75.0 bits (184), Expect = 1e-17 Identities = 33/165 (20%), Positives = 69/165 (41%), Gaps = 6/165 (3%) Query: 27 LYTGISQKEGNEMLALLRSEGVSADKQADKDGTVRLLVEESDIAEAVEVLKRKGYPRENF 86 L++ +S ++G ++A L + + V + E L ++G P+ Sbjct: 53 LFSNLSDQDGGAIVAQLTQMNIPYR--FANGSGA-IEVPADKVHELRLRLAQQGLPKGG- 108 Query: 87 STLKDVFPKDGLISSPIEERARLNYAKAQEISHTLSEIDGVLVARVHVVLPEERDGLGRK 146 + ++ ++ S E+ A E++ T+ + V ARVH+ +P + R+ Sbjct: 109 AVGFELLDQEKFGISQFSEQVNYQRALEGELARTIETLGPVKSARVHLAMP-KPSLFVRE 167 Query: 147 SSPASASVFIKHAADVQLD-AYVPQIKQLVNNGIEGLSYDRISVV 190 SASV + LD + + LV++ + GL +++V Sbjct: 168 QKSPSASVTVTLEPGRALDEGQISAVVHLVSSAVAGLPPGNVTLV 212
>PF09025#YopR Core Length = 143 Score = 204 bits (519), Expect = 5e-71 Identities = 142/143 (99%), Positives = 142/143 (99%) Query: 1 MSRIDTPPGFAVYPSASPKAANLPAVDQVLAFEQALGGEPPAAGRRLAGLENGALSERLL 60 MSRIDTPPGFAVYPSASPKAANLPAVDQVLAFEQALGGEPPAAGRRLAGLENGAL ERLL Sbjct: 1 MSRIDTPPGFAVYPSASPKAANLPAVDQVLAFEQALGGEPPAAGRRLAGLENGALGERLL 60 Query: 61 QRFAQPLQGLEADRLELKAMLRAELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQ 120 QRFAQPLQGLEADRLELKAMLRAELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQ Sbjct: 61 QRFAQPLQGLEADRLELKAMLRAELPLGRQQQTFLLQLLGAVEHAPGGEYLAQLARRELQ 120 Query: 121 VLIPLNGMLDNLVRNSHKLDLES 143 VLIPLNGMLDNLVRNSHKLDLES Sbjct: 121 VLIPLNGMLDNLVRNSHKLDLES 143
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 818 bits (2114), Expect = 0.0 Identities = 375/600 (62%), Positives = 473/600 (78%), Gaps = 7/600 (1%) Query: 1 MRRLLIGGLLALLPGAVLRAQPLDWPSLPYDYVAQGESLRDVLANFGANYDASVIVSDKV 60 +R+L G LL L + AQ LDW +PY YVA+GESLRD+L +FGANYDA+V+VSDK+ Sbjct: 9 FKRVLTGTLLLLSSYSW--AQELDWLPIPYVYVAKGESLRDLLTDFGANYDATVVVSDKI 66 Query: 61 NDQVSGRFDLESPQAFLQLMASLYNLGWYYDGTVLYVFKTTEMQSRLVRLEQVGEAELKR 120 ND+VSG+F+ ++PQ FLQ +ASLYNL WYYDG VLY+FK +E+ SRL+RL++ AELK+ Sbjct: 67 NDKVSGQFEHDNPQDFLQHIASLYNLVWYYDGNVLYIFKNSEVASRLIRLQESEAAELKQ 126 Query: 121 ALTAAGIWEPRFGWRADPSGRLVHVSGPGRYLELVEQTAQVLEQQYTLRSEKTGDLSVEI 180 AL +GIWEPRFGWR D S RLV+VSGP RYLELVEQTA LEQQ +RSEKTG L++EI Sbjct: 127 ALQRSGIWEPRFGWRPDASNRLVYVSGPPRYLELVEQTAAALEQQTQIRSEKTGALAIEI 186 Query: 181 FPLRYAVAEDRKIEYRDDEIEAPGIASILSRVLSDANVVAVGDEPGKLRPGP--QSSHAV 238 FPL+YA A DR I YRDDE+ APG+A+IL RVLSDA + V + ++ S+ A Sbjct: 187 FPLKYASASDRTIHYRDDEVAAPGVATILQRVLSDATIQQVTVDNQRIPQAATRASAQAR 246 Query: 239 VQAEPSLNAVVVRDHKDRLPMYRRLIEALDRPSARIEVGLSIIDINAENLAQLGVDWSAG 298 V+A+PSLNA++VRD +R+PMY+RLI ALD+PSARIEV LSI+DINA+ L +LGVDW G Sbjct: 247 VEADPSLNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVDINADQLTELGVDWRVG 306 Query: 299 IRLGNNKSIQIRTTGQDSEEGGGAGNGAVGSLVDSRGLDFLLAKVTLLQSQGQAQIGSRP 358 IR GNN + I+TTG S A NGA+GSLVD+RGLD+LLA+V LL+++G AQ+ SRP Sbjct: 307 IRTGNNHQVVIKTTGDQS---NIASNGALGSLVDARGLDYLLARVNLLENEGSAQVVSRP 363 Query: 359 TLLTQENTQAVLDQSETYYVRVTGERVAELKAITYGTMLKMTPRVVTLGDTPEISLSLHI 418 TLLTQEN QAV+D SETYYV+VTG+ VAELK ITYGTML+MTPRV+T GD EISL+LHI Sbjct: 364 TLLTQENAQAVIDHSETYYVKVTGKEVAELKGITYGTMLRMTPRVLTQGDKSEISLNLHI 423 Query: 419 EDGSQKPNSAGLDKIPTINRTVIDTIARVGHGQSLLIGGIYRDELSQSQRKVPWLGDIPY 478 EDG+QKPNS+G++ IPTI+RTV+DT+ARVGHGQSL+IGGIYRDELS + KVP LGDIPY Sbjct: 424 EDGNQKPNSSGIEGIPTISRTVVDTVARVGHGQSLIIGGIYRDELSVALSKVPLLGDIPY 483 Query: 479 LGALFRTTADTVRRSVRLFLIEPRLVDDGVGHYLALNNRRDLRGGLLEIDELSNQSLSLR 538 +GALFR ++ RR+VRLF+IEPR++D+G+ H+LAL N +DLR G+L +DE+SNQS +L Sbjct: 484 IGALFRRKSELTRRTVRLFIIEPRIIDEGIAHHLALGNGQDLRTGILTVDEISNQSTTLN 543 Query: 539 KLLGSARCQALAPARAEQERLRQAGQGSFLTPCRMGAQEGWRVTDGACPKDGAWCVGAER 598 KLLG ++CQ L A+ Q+ L Q + S+LT C+M GWRV +GAC +WCV A + Sbjct: 544 KLLGGSQCQPLNKAQEVQKWLSQNNKSSYLTQCKMDKSLGWRVVEGACTPAQSWCVSAPK 603
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 91.4 bits (227), Expect = 8e-27 Identities = 25/120 (20%), Positives = 41/120 (34%), Gaps = 5/120 (4%) Query: 2 DHLLSGLATRLGQGPFVADRTGSYHLRIDGQSVLLLRQGDDLLLESPLEHAPLDPQRDQQ 61 LL + L P V D G+ ++ ID L L D E L L+P + Sbjct: 7 KTLLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLS--CDYARERLLLIGLLEP--HKD 62 Query: 62 GLLRVLLSRVASWSRRYPQAIVLDADGRLLLQA-RLGLDGLDPERLERALAAQVGLLEAL 120 + LL+ + + LD L + + L L+R +A + + Sbjct: 63 IPQQCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMRGW 122
>PF05932#Tir chaperone protein (CesT) Length = 127 Score = 47.5 bits (113), Expect = 7e-10 Identities = 27/118 (22%), Positives = 49/118 (41%), Gaps = 4/118 (3%) Query: 10 LLAEFAGRIGLPSLSLDEEGMASLLFDEQVGVTLLLLAERERLLLEADVAGIDVLGEGIF 69 LL +F+ + + L D+ G +++ D +TL RERLLL + + Sbjct: 9 LLDDFSRSLEMQPLVFDDHGTCNMIIDNTFALTLSCDYARERLLLIGLLEP---HKDIPQ 65 Query: 70 RQLASFNRHWHRFDLH-FGFDELTGKVQLYAQILAAQLTLECFEATLANLLDHAEFWQ 126 + L + + G DE +G Y I +L++ + +A LL+ W+ Sbjct: 66 QCLLAGALNPLLNAGPGLGLDEKSGLYHAYQSIPREKLSVPTLKREMAGLLEWMRGWR 123
>PF05844#YopD protein Length = 295 Score = 385 bits (989), Expect = e-137 Identities = 291/295 (98%), Positives = 293/295 (99%) Query: 1 MIDTQYSLAATQAAIPSEPIAPGAAGRSVGTPQAAADLPQVPAARADRVELNAPRQVLDP 60 MIDTQYSLAATQAAIPSEPIAPGAAGRSVGTPQAAA+LPQVPAARADRVELNAPRQVLDP Sbjct: 1 MIDTQYSLAATQAAIPSEPIAPGAAGRSVGTPQAAAELPQVPAARADRVELNAPRQVLDP 60 Query: 61 VRMEAAGSELDSSVELLLILFRIAQKARELGVLQRDNENQSIIHAQKAQVDEMRSGATLM 120 VRMEAAGSELDSSVELLLILFRIAQKARELGVLQRDNENQ+IIHAQKAQVDEMRSGATLM Sbjct: 61 VRMEAAGSELDSSVELLLILFRIAQKARELGVLQRDNENQAIIHAQKAQVDEMRSGATLM 120 Query: 121 IAMAVIAGVGALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDAKMQALGKTSDED 180 IAMAVIAGVGALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDAKMQALGKTSDED Sbjct: 121 IAMAVIAGVGALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDAKMQALGKTSDED 180 Query: 181 RKIVGKVWAADQVQDSVALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQA 240 RKIVGKVWAADQ QDSVALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQA Sbjct: 181 RKIVGKVWAADQAQDSVALRAAGRAFESRNGALQVANTVIQSFVQMANASVQVRQGESQA 240 Query: 241 SAREGEVNATIGQSQKQKVEDQMSFDAGFMKDVLQLIQQYTQSHNQAWRAAAGVV 295 SARE EVNATIGQSQKQKVEDQMSFDAGFMKDVLQLIQQYTQSHNQAWRAAAGVV Sbjct: 241 SAREEEVNATIGQSQKQKVEDQMSFDAGFMKDVLQLIQQYTQSHNQAWRAAAGVV 295
>LCRVANTIGEN#Low calcium response V antigen signature. Length = 326 Score = 344 bits (884), Expect = e-121 Identities = 115/296 (38%), Positives = 171/296 (57%), Gaps = 32/296 (10%) Query: 25 ASAEQEELLALLRSERIVLAHAGQPLSEAQVL-------------KALAWLLAANPSAPP 71 S+ EEL+ L++ + I ++ P +++V K LA+ L + Sbjct: 28 GSSVLEELVQLVKDKNIDISIKYDPRKDSEVFANRVITDDIELLKKILAYFLPEDAILKG 87 Query: 72 GQ-------GLEVLREVLQARRQPGAQWDLREFLVSAYFSLHG-RLDEDVIGVYKDVLQT 123 G G++ ++E L++ P QW+LR F+ +FSL R+D+D++ V D + Sbjct: 88 GHYDNQLQNGIKRVKEFLES--SPNTQWELRAFMAVMHFSLTADRIDDDILKVIVDSMNH 145 Query: 124 QDGKRKALLDELKALTAELKVYSVIQSQINAALSAKQGIRIDAGGIDLVDPTLYGYAVGD 183 R L +EL LTAELK+YSVIQ++IN LS+ I I I+L+D LYGY + Sbjct: 146 HGDARSKLREELAELTAELKIYSVIQAEINKHLSSSGTINIHDKSINLMDKNLYGYT-DE 204 Query: 184 PRWKDSPEYALLSNLDTFSGKL--------SIKDFLSGSPKQSGELKGLSDEYPFEKDNN 235 +K S EY +L + + ++ SIKDFL K++G L L + Y + KDNN Sbjct: 205 EIFKASAEYKILEKMPQTTIQVDGSEKKIVSIKDFLGSENKRTGALGNLKNSYSYNKDNN 264 Query: 236 PVGNFATTVSDRSRPLNDKVNEKTTLLNDTSSRYNSAVEALNRFIQKYDSVLRDIL 291 + +FATT SD+SRPLND V++KTT L+D +SR+NSA+EALNRFIQKYDSV++ +L Sbjct: 265 ELSHFATTCSDKSRPLNDLVSQKTTQLSDITSRFNSAIEALNRFIQKYDSVMQRLL 320
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 284 bits (727), Expect = 4e-98 Identities = 134/294 (45%), Positives = 181/294 (61%), Gaps = 7/294 (2%) Query: 1 MDILQSSSAAPLA-----PREAANAPAQQAGGSFQGERVHYVSVS-QSLADAAEELTFAF 54 M L + S P A++ Q G F+GE V VS + QS+AD AEE+TF F Sbjct: 1 MTTLHNLSYGNTPLHNERPEIASSQIVNQTLGQFRGESVQIVSGTLQSIADMAEEVTFVF 60 Query: 55 SERAEKSLAKRRLSDAHARLSEVQAMLQEYWKRIPDLESQQKLEALIAHLGSGQLSSLAQ 114 SER E SL KR+LSD+ AR+S+V+ + +Y ++P+LE +Q + L++ L + SL+Q Sbjct: 61 SERKELSLDKRKLSDSQARVSDVEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQ 120 Query: 115 LSAYLEGFSSEISQRFLALSRARDVLAGRPEARAMLALVDQALLRMADEQGLEIELGLRI 174 L AYLEG S E S++F L RD L GRPE + LV+QAL+ MA+EQG I LG RI Sbjct: 121 LKAYLEGKSEEPSEQFKMLCGLRDALKGRPELAHLSHLVEQALVSMAEEQGETIVLGARI 180 Query: 175 EPLAAEASAAGVGDIQALRDTYRDAVLDYRGLSAAWQDIQARFAATPLERVVAFLQKALS 234 P A S +GV +Q LRDTYRDAV+ Y+G+ A W D+Q RF ++ V+ FLQKALS Sbjct: 181 TPEAYRESQSGVNPLQPLRDTYRDAVMGYQGIYAIWSDLQKRFPNGDIDSVILFLQKALS 240 Query: 235 ADLDSQSSRLDPVKLERVMSDMHKLRVLGGLAEQVGALWQVLVTGERGHGIRAF 288 ADL SQ S KL V+SD+ KL+ G +++QV WQ G + +G+R F Sbjct: 241 ADLQSQQSGSGREKLGIVISDLQKLKEFGSVSDQVKGFWQFFSEG-KTNGVRPF 293
>TYPE3OMOPROT#Type III secretion system outer membrane O protein family signature. Length = 303 Score = 83.5 bits (206), Expect = 1e-20 Identities = 46/177 (25%), Positives = 73/177 (41%), Gaps = 14/177 (7%) Query: 130 RLALWLDGDPATLLARLPPRPSAQRLAIPLRLSLQWPGLPLDTGELRTLEPGDLLLLPAG 189 R LW + P L A RP R + + L L + GD+LL+ Sbjct: 126 RGGLWFEHLPE-LPAVGGGRPKMLRWPLRFVIGSSDTQRSL----LGRIGIGDVLLIRTS 180 Query: 190 HRPDAALLGVLEGRPWARCQLHSTQL-ELLDMH----DTPSLADGEDLHELDQLPIPVSF 244 A + + ++ + E LD+ + + E L L+QLP+ + F Sbjct: 181 R----AEVYCYAKKLGHFNRVEGGIIVETLDIQHIEEENNTTETAETLPGLNQLPVKLEF 236 Query: 245 EVGRRTLDLHTLSTLQPGSLLDLDSALDGEVRILANQRCLGIGELVRLQDRLGVRVT 301 + R+ + L L + LL L + + V I+AN LG GELV++ D LGV + Sbjct: 237 VLYRKNVTLAELEAMGQQQLLSLPTNAELNVEIMANGVLLGNGELVQMNDTLGVEIH 293
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 29.5 bits (66), Expect = 0.024 Identities = 15/51 (29%), Positives = 23/51 (45%), Gaps = 2/51 (3%) Query: 317 IGDVVRGAMLAHKASEEGVMVAERIAGHKAQMNYDLIPSVIYTHPEIAWVG 367 +GD+V G M A+ + + I A + Y S++Y P IA G Sbjct: 110 LGDIVLGEMAW--AATKAALAGAGIGVVAAALGYTQWLSLLYALPVIALTG 158
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 29.5 bits (66), Expect = 0.034 Identities = 17/42 (40%), Positives = 23/42 (54%) Query: 466 GTSRSTPSGKPTVRADSSDGKLSTRAGLVFKPLENGRVYFSY 507 G + + PT + D+SD S AGL F P+EN + FSY Sbjct: 109 GYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSY 150
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 108 bits (270), Expect = 2e-27 Identities = 82/400 (20%), Positives = 164/400 (41%), Gaps = 15/400 (3%) Query: 17 TFIASLDISIVNLALPTLQYALDTDLAGLQWVVDAYALCLSAFMLSSGPLSDRYGRKLTW 76 +F + L+ ++N++LP + + A WV A+ L S G LSD+ G K Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 77 LLGVGLFSFGSLLCALATS-LPLLLFGRAVQGIAGALLIPGALSILTQAFHDPGQRAQVI 135 L G+ + FGS++ + S LL+ R +QG GA P + ++ + R + Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGA-GAAAFPALVMVVVARYIPKENRGKAF 141 Query: 136 GGWTSFSALSLILGPLLGGLLVEHAGWQSIFLINLPLGLLALALGLWGIEETAHPEHAAF 195 G S A+ +GP +GG++ + W + LI + + L +E H F Sbjct: 142 GLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGH--F 199 Query: 196 DPLGQLLSVVWLGALTYALIAAGEGGWLSPTAWPALLLAGVGLLGFLFVERRTARPLLPL 255 D G +L V + + + L+++ + L F+ R+ P + Sbjct: 200 DIKGIILMSVGIVFFMLFTTSY---------SISFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 256 GLFRQAGFAVCNLASFVLGFSGYASLFFLSLFFQQVQGASAQQAGF-YLAPQFLAMGALS 314 GL + F + L ++ + + + + V S + G + P +++ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 315 MLFGRLQRHVPLRRLLVLGYLVIGLAMLALAACGTGTAYPWVGLLLVALGLGMGLAVPGT 374 + G L +L +G + ++ L + T++ ++ +++V + G+ Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSW-FMTIIIVFVLGGLSFTKTVI 369 Query: 375 GLAVMASVARERSGMASATMNTLRQAGMAVGIALLGALLS 414 V +S+ ++ +G + +N GIA++G LLS Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>OMADHESIN#Yersinia outer membrane adhesin signature. Length = 455 Score = 24.9 bits (53), Expect = 0.048 Identities = 20/72 (27%), Positives = 26/72 (36%), Gaps = 9/72 (12%) Query: 22 QTDLNGKPMAGVGHQVVCP---------LCKGTFPITEGSALLDVNGVPVALHGMKTACG 72 Q N P G+ + V P KG I G+ G VA+ A G Sbjct: 38 QISPNADPALGLEYPVRPPVPGAGGLNASAKGIHSIAIGATAEAAKGAAVAVGAGSIATG 97 Query: 73 ASLIASGPLGAA 84 + +A GPL A Sbjct: 98 VNSVAIGPLSKA 109
>cloacin#Cloacin signature. Length = 551 Score = 30.1 bits (67), Expect = 0.022 Identities = 15/48 (31%), Positives = 20/48 (41%) Query: 398 SAGGSGGGRRRGGDYASSSGSSSSSSSSSSSDSFSGGGGSSGGGGASG 445 + G GGG G ++S + S S G G+ GG G SG Sbjct: 25 TGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSG 72
>cloacin#Cloacin signature. Length = 551 Score = 36.2 bits (83), Expect = 2e-04 Identities = 15/37 (40%), Positives = 19/37 (51%) Query: 379 GGGGSSGSSGGGSSSSSSSSSGGFSGGGGSSGGGGAS 415 GGG SG GG S + G SGGG +GG ++ Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 34.7 bits (79), Expect = 6e-04 Identities = 16/39 (41%), Positives = 20/39 (51%) Query: 378 SGGGGSSGSSGGGSSSSSSSSSGGFSGGGGSSGGGGASG 416 +G G G+S G SS ++ GG SG G GGG G Sbjct: 25 TGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHG 63 Score = 33.9 bits (77), Expect = 0.001 Identities = 20/48 (41%), Positives = 22/48 (45%), Gaps = 9/48 (18%) Query: 379 GGGGSSGSS--------GGGSSSSSSSSSGGFSGGGGSSG-GGGASGS 417 GGG S GS GGGS S G G GG +G GG SG+ Sbjct: 30 GGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGT 77 Score = 33.1 bits (75), Expect = 0.002 Identities = 16/42 (38%), Positives = 18/42 (42%) Query: 377 LSGGGGSSGSSGGGSSSSSSSSSGGFSGGGGSSGGGGASGSW 418 ++GG G GG S S SS GGG SG GS Sbjct: 20 INGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Score = 32.8 bits (74), Expect = 0.003 Identities = 17/44 (38%), Positives = 21/44 (47%), Gaps = 5/44 (11%) Query: 379 GGGGSSGSSGGGSSSSSS-----SSSGGFSGGGGSSGGGGASGS 417 G G S G G SS ++ S SG GGG G GG +G+ Sbjct: 27 LGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGN 70 Score = 32.0 bits (72), Expect = 0.004 Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 373 GQVRLSGGGGSSGSSGGGSSSS----SSSSSGGFSGGGGSSGGGGASGS 417 G L GGG+S SG S ++ S S + GG G GGG S Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNS 71 Score = 32.0 bits (72), Expect = 0.005 Identities = 14/37 (37%), Positives = 16/37 (43%) Query: 381 GGSSGSSGGGSSSSSSSSSGGFSGGGGSSGGGGASGS 417 GG SGS S + GG GG SG GG + Sbjct: 47 GGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSA 83 Score = 30.5 bits (68), Expect = 0.013 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Query: 377 LSGGGGSSGSSGGGSSSSSSSSSGGFSGGGGSSGGGGASG 416 +SGG G G+ S+S + +GG +G G G SG Sbjct: 1 MSGGDGRG--HNTGAHSTSGNINGGPTGLGVGGGASDGSG 38 Score = 29.7 bits (66), Expect = 0.026 Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 3/38 (7%) Query: 384 SGSSGGGSSSSSSSSSG---GFSGGGGSSGGGGASGSW 418 SG G G ++ + S+SG G G G GG W Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGW 39
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 336 bits (864), Expect = e-116 Identities = 98/345 (28%), Positives = 183/345 (53%), Gaps = 2/345 (0%) Query: 9 DKTEEPTEKRRREAREKGQLPRSRELNTLAILMAGAGGLLIYGADLAGALLRLMRSNFEL 68 +KTE+PT K+ R+AR+KGQ+ +S+E+ + A+++A + L+ +LM E Sbjct: 4 EKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIPAEQ 63 Query: 69 SRETAMNTESMLQLLGASAYLAAQGLWPILLMLLVAAIVGPIALGGWLFSMDALQPKFSR 128 S ++++ ++ +P+L + + AI + G+L S +A++P + Sbjct: 64 SYLPF--SQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIKK 121 Query: 129 LNPLSGLKRMFSAKSLLELSKALIKFLVVLAVALLVLSADRDALLALAHQPLEQAILHSV 188 +NP+ G KR+FS KSL+E K+++K +++ + +++ + LL L +E Sbjct: 122 INPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLLG 181 Query: 189 RVVGWSAFWMACSLLLIAAVDVPYQIWDNRQKLLMTKQEVRDEYKDSEGKPEVKSKIRQM 248 +++ ++I+ D ++ + ++L M+K E++ EYK+ EG PE+KSK RQ Sbjct: 182 QILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQF 241 Query: 249 QREMAQRRMMAAVPEADVVITNPTHFAVALKYDPAGGGAPLLLAKGNDFLALKIREVAQE 308 +E+ R M V + VV+ NPTH A+ + Y PL+ K D +R++A+E Sbjct: 242 HQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAEE 301 Query: 309 HKVMVMESPALARAVYYSTELDQEIPAGLYLAVAQVLAYVYQLKQ 353 V +++ LARA+Y+ +D IPA A A+VL ++ + Sbjct: 302 EGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNI 346
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 135 bits (341), Expect = 7e-41 Identities = 96/232 (41%), Positives = 143/232 (61%), Gaps = 2/232 (0%) Query: 1 MLELTNAQIGGWIASFVLPLFRVAALLMTMPVIGTQLVPVRVRLYLALGVCVVLVPNLPP 60 ML++T+ Q W+ + PL RV AL+ T P++ + VP RV+L LA+ + + P+LP Sbjct: 1 MLQVTSEQWLSWLNLYFWPLLRVLALISTAPILSERSVPKRVKLGLAMMITFAIAPSLPA 60 Query: 61 MPQVDALSMKAMLLIGEQILVGALLGFSLQLLFHAFVIAGQIISMQMGLGFASMVDPANG 120 S A+ L +QIL+G LGF++Q F A AG+II +QMGL FA+ VDPA+ Sbjct: 61 NDVPV-FSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASH 119 Query: 121 VSVPVLGQFFTMLVTLLFLAMNGHLVVFEVIAESFVTLPVGEGLSGNHFWI-IAGKLGWV 179 +++PVL + ML LLFL NGHL + ++ ++F TLP+G ++ ++ + + Sbjct: 120 LNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPLNSNAFLALTKAGSLI 179 Query: 180 MGAALLLALPAITALLVVNLAFGAMTRAAPQLNIFSIGFPLTLVLGLVILWI 231 L+LALP IT LL +NLA G + R APQL+IF IGFPLTL +G+ ++ Sbjct: 180 FLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAA 231
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 54.8 bits (132), Expect = 9e-14 Identities = 24/75 (32%), Positives = 43/75 (57%) Query: 7 LDLFREALWLTAMIVGVLVVPSLLVGLVVAMFQAATQINEQTLSFLPRLMVILLTLIVLG 66 + +AL+L ++ G + + ++GL+V +FQ TQ+ EQTL F +L+ + L L +L Sbjct: 5 VFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFLLS 64 Query: 67 PWLLRQLMEYTQTLI 81 W L+ Y + +I Sbjct: 65 GWYGEVLLSYGRQVI 79
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 40.6 bits (95), Expect = 2e-05 Identities = 26/201 (12%), Positives = 64/201 (31%), Gaps = 13/201 (6%) Query: 3 RASLHMLLCQFAMALGLLLSLGSEAWAARPAPQAAVDLEAPPALAEDASLDQLNAQLDLI 62 A A + + + L P ++ S +++ LI Sbjct: 133 EADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYF-QNVSEEEVLRLTSLI 191 Query: 63 RQRVTADASDDLLAELRQSALQVQRQ-ADALLALRVADIERLDDQLKVIGPPQPDEAESL 121 +++ + + EL + +R A + +L + SL Sbjct: 192 KEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD--------DFSSL 243 Query: 122 AAQRQALTRQKNALLDDERQATQLGQSSRDLAAQIVNLRRSLFNSQISSRAATPFSPSFW 181 ++ K+A+L+ E + + R +Q+ + + +++ + T + Sbjct: 244 LHKQAI---AKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEI 300 Query: 182 STLIRPTDDDLRRLDKLKAEA 202 +R T D++ L A+ Sbjct: 301 LDKLRQTTDNIGLLTLELAKN 321
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.1 bits (140), Expect = 1e-12 Identities = 24/149 (16%), Positives = 55/149 (36%) Query: 14 QPQQARSSELVASILEAAVQVLASEGAQRFTTARVAERAGVSIGSLYQYFPNKAAILFRL 73 + + + E IL+ A+++ + +G + +A+ AGV+ G++Y +F +K+ + + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 74 QSDEWRRTTRLLGEILEDTARPPLARLRRLVLAFVRSECEEAAIRVALSDAAPLYRDADE 133 L E PL+ LR +++ + S E R+ + E Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 134 AREVKAEGARVFQAFLREALPEVAEAERS 162 V+ + + + Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEA 151
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 75.8 bits (186), Expect = 2e-19 Identities = 37/202 (18%), Positives = 72/202 (35%), Gaps = 10/202 (4%) Query: 5 SRQQENAEATREALLESALSAFIEHGYGGVSIDAIAREARVTKGAFYHHFGSKQELLAEC 64 + ++ A+ TR+ +L+ AL F + G S+ IA+ A VT+GA Y HF K +L +E Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 65 YERQVRTIAEDLDRVPAHVDKWAEAAALA--EAFIDSVMARGKRQL----SLQEVITVVG 118 +E I E A + ++S + +R+L + V Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 119 WE---RWKRIDSRHTLRYVGRLVDELAASGELK-DYRRETLVGQLYGFLTQAAMSLRDAR 174 + +R + + + + + L D + G+++ + A Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 175 NKRQAANEVKAIIRDFLYSLRR 196 E + + L Sbjct: 183 QSFDLKKEARDYVAILLEMYLL 204
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 44.9 bits (106), Expect = 4e-07 Identities = 33/133 (24%), Positives = 62/133 (46%), Gaps = 3/133 (2%) Query: 53 LVWGLAQPFTGALADRYGAARAVLVGGLLYALGLVLMGLSQSATGLSLSAGLLIGLGLSG 112 L + + G L+D+ G R +L G ++ G V+ + S L + A + G G + Sbjct: 60 LTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAG-AA 118 Query: 113 TSFSVILGAVGRAVPAEQRSMAMGISSAAGSFGQFAMLPGTLGLIG-WLGWSSALLALGL 171 ++++ V R +P E R A G+ + + G+ + P G+I ++ WS LL + Sbjct: 119 AFPALVMVVVARYIPKENRGKAFGLIGSIVAMGE-GVGPAIGGMIAHYIHWSYLLLIPMI 177 Query: 172 LVALIVPLAGLMK 184 + + L L+K Sbjct: 178 TIITVPFLMKLLK 190
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.9 bits (129), Expect = 3e-11 Identities = 22/107 (20%), Positives = 40/107 (37%), Gaps = 1/107 (0%) Query: 1 MGRRRTIDRDQLLDAAEAVIGREGAAGLTIDAVAKEMGITKGGVQYCFGTKDALIDAIFE 60 + R +LD A + ++G + ++ +AK G+T+G + + F K L I+E Sbjct: 5 TKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWE 64 Query: 61 RWGKAYDSLFEAVAGKQP-TPLTRVRAHAEATQRSDELSSSKAAALM 106 L K P PL+ +R S + + Sbjct: 65 LSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLME 111
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 195 bits (497), Expect = 5e-59 Identities = 91/398 (22%), Positives = 177/398 (44%), Gaps = 14/398 (3%) Query: 18 FLIIIDMTVLYTALPRLTHDLGATAAEKLWIVNAYPLVVAGLLPGAGLLSDRLGHKRLFL 77 F +++ VL +LP + +D A W+ A+ L + G LSD+LG KRL L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 78 AGLPLFGLASLCAAFAPSAAA-LIAARAGLAVGAALMMPATLSIVRHVFQDERERALAIG 136 G+ + S+ S + LI AR GAA PA + +V + + R A G Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA-AFPALVMVVVARYIPKENRGKAFG 142 Query: 137 IWASVASAGAALGPVVGGVLLEFFWWGSVFLINVPVVVVALLLALPAIPACGGQSRRPWD 196 + S+ + G +GP +GG++ + W +L+ +P++ + + L + + + +D Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFD 200 Query: 197 ALGSLQVMFGLVGVVYAIKELSTRAPDFGLAVLAALGGMLCLYLFVRRQRRAREPMIDFT 256 G + + G+V + L T + +++ +L +FV+ R+ +P +D Sbjct: 201 IKGIILMSVGIVFFM-----LFTTSYSISFLIVS----VLSFLIFVKHIRKVTDPFVDPG 251 Query: 257 LFRNRRFARGVAVALVATMALVGMELVFSQHLQLVQGLTPLKAG-LFVLPIPLASLVVGP 315 L +N F GV + + G + ++ V L+ + G + + P ++ ++ G Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGY 311 Query: 316 LAGWLVPRWGENRVMCASLLFGSAGLLGLALSYQSATGAQLASLVLLGVGFGGAMTAAST 375 + G LV R G V+ + F S L + ++ + +V + G T ST Sbjct: 312 IGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSFTKTVIST 371 Query: 376 AVMLNVDEQSSGMAAAIEDVSYELGGVIGVTLLGSLMS 413 V ++ +Q +G ++ + + L G+ ++G L+S Sbjct: 372 IVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 30.2 bits (68), Expect = 0.030 Identities = 29/154 (18%), Positives = 38/154 (24%), Gaps = 37/154 (24%) Query: 153 RRGDGQGAKPFFSAGYGTHQ-----TLEGSAGVSG-------GAGNGWYSLGVSSFDTAG 200 R G+ Q KP F H T+ G ++ G G +LG S D Sbjct: 384 RSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQ 443 Query: 201 INTKRAGT-------------------------AGYEPDRDGYRNLSGNLRGGYRFDNGL 235 N+ GY GY N + N Sbjct: 444 ANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIE 503 Query: 236 ELDGTLLRAKSHNDYDQVFGNSGFNANADGEQNL 269 DG + DY + N Q L Sbjct: 504 TQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQL 537
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 29.4 bits (66), Expect = 0.020 Identities = 9/30 (30%), Positives = 15/30 (50%), Gaps = 1/30 (3%) Query: 5 VIVVG-AGIVGSACAHELARRGLDVLVLDS 33 +V G AG +G + L G V+ +D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDN 32
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 109 bits (275), Expect = 3e-28 Identities = 80/418 (19%), Positives = 162/418 (38%), Gaps = 30/418 (7%) Query: 15 LCILLAGQLLPMIDFSIVNVALDALAHSLGASETELELIVAVYGVAFAVCLAMGGRLGDN 74 LCIL +++ ++NV+L +A+ + + + F++ A+ G+L D Sbjct: 19 LCIL---SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQ 75 Query: 75 YGRRRLFDLGVALFAVASLLCGLAGS-VWLLLVARALQGVGAALVVPQILATLHVSLSGH 133 G +RL G+ + S++ + S LL++AR +QG GAA ++ + + Sbjct: 76 LGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKE 135 Query: 134 AHSRALAAYGAIGGLAFVVGQVLGGFLVSADIGGLGWRSVFLINLPICLGILLCSRRWVP 193 +A G+I + VG +GG + + W +L+ +P+ I + + Sbjct: 136 NRGKAFGLIGSIVAMGEGVGPAIGGMIAHY----IHWS--YLLLIPMITIITVPFLMKLL 189 Query: 194 ETRAEHAARVDAPGTLLLAALILCLLLPLALGPSLHWS-WPCALLLAAAVPLLAWLWRTE 252 + D G +L++ I+ +L + L+ Sbjct: 190 KKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIF------------- 236 Query: 253 LRQERRQAWPLLPPSLLRLPSIRFGLLLAILFFACWSGFMFALALALQAGAGLSPVQAGN 312 ++ R+ P + P L + G+L + F +GF+ + ++ LS + G+ Sbjct: 237 VKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGS 296 Query: 313 AFIALGA-SYFVSALLTARVAARIGPVRLLLLGCVIQMCGLLGLMLTLQRVWPQPGILNL 371 I G S + + + R GP+ +L +G L + + Sbjct: 297 VIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFL-----LETTSWFM 351 Query: 372 APATLVIGFGQAFIVSSFFRIGLSEVPAAQAGAGSAMLATVQQASLGLGSALLGAVFA 429 + + G +F + I S + +AGAG ++L S G G A++G + + Sbjct: 352 TIIIVFVLGGLSFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLS 409
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 3e-18 Identities = 33/119 (27%), Positives = 52/119 (43%), Gaps = 5/119 (4%) Query: 741 THVLLVDDDRMVRYTTALLLGDLGYQVSEAASAEEALGEVERGLAPDLLVTDHLMADKTG 800 +L+ DDD +R L GY V ++A + G DL+VTD +M D+ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPDENA 62 Query: 801 VQLAEELRQRFPQLPVLVITGYANL----RPEQLNGFEVLTKPFRHNELAERLARLLEA 855 L +++ P LPVLV++ + + ++ L KPF EL + R L Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>SUBTILISIN#Subtilisin serine protease family (S8) signature. Length = 326 Score = 88.4 bits (219), Expect = 3e-21 Identities = 60/293 (20%), Positives = 104/293 (35%), Gaps = 51/293 (17%) Query: 256 VRIGVIERDVDFDAPDFADYLGPCKAPAPRTCLYARDAERPDNHGSTVAGILAARWDQGG 315 V++ V++ D D PD + + + + HG+ VAG +AA Sbjct: 43 VKVAVLDTGCDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAA----TE 98 Query: 316 NSGFLRGLDRASQGFEVIVERNSDAGITANVAASVN-LVEDGVRVLNWSWGIHRVGARDV 374 N + G+ + + V +G + + +E V +++ S G Sbjct: 99 NENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSLG------GPE 152 Query: 375 DGDEVDSLVRSGIAMSGYEELLEEFFLWLRKKHPDVLVVNSAGN-GSSYSGTDEYRLPSS 433 D E+ V+ +A +LV+ +AGN G TDE P Sbjct: 153 DVPELHEAVKKAVA-------------------SQILVMCAAGNEGDGDDRTDELGYPGC 193 Query: 434 FVTEQLLVVGGHQRSERQGLAVDDPAYAVKRSTSNVDMRVDVTAAACTHASTLERDARGE 493 + +++ VG A++ +A SN + VD+ A ST+ + Sbjct: 194 Y--NEVISVG----------AINFDRHAS--EFSNSNNEVDLVAPGEDILSTV-PGGKYA 238 Query: 494 VHCGTSYATPMVAGTVAAMLSLNPRLR-----PEEIRMLLRRSAMTIGGDYDF 541 GTS ATP VAG +A + L E+ L + + +G Sbjct: 239 TFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKRTIPLGNSPKM 291
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 121 bits (305), Expect = 1e-32 Identities = 61/368 (16%), Positives = 110/368 (29%), Gaps = 68/368 (18%) Query: 66 AVSAQVSGYVAEVLVADDADVQAGDLLLRLDPRDFR-------QRLRAAEAREAAAQAAL 118 + + V E++V + V+ GD+LL+L L A + Q Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILS 157 Query: 119 EAQ-------------------------------RAKLETLDRQLLEQAQTISRARADGE 147 + + + T Q ++ + + RA+ Sbjct: 158 RSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERL 217 Query: 148 AARAEWRRAETDWR-------RYRQLADEHATSRQRLENADAAHQRARAAARRANAEEGR 200 A R E R + L + A ++ + + + A R ++ + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQ 277 Query: 201 QRAARDVLKSR--------RREAEAALAQRQAELQEAAAARELARHALDDTEIRAPFAGR 252 + K + E L Q + + IRAP + + Sbjct: 278 IESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVK 337 Query: 253 VGQRKVRLR-QYVTPGLPLLAVVPLEQAYVV-ANYKETQLERIRPGQPVELEVDTFGRRW 310 V Q KV VT L+ +VP + V A + + I GQ ++V+ F Sbjct: 338 VQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTR 397 Query: 311 RGRVDSVAPASGAVFALLPPDNATGNFTKIVQRFPVRIRLDADAAERG----RLLPGMSV 366 G + + D +V F V I ++ + G L GM+V Sbjct: 398 YGYLV-------GKVKNINLDAIEDQRLGLV--FNVIISIEENCLSTGNKNIPLSSGMAV 448 Query: 367 IATVDTRE 374 A + T Sbjct: 449 TAEIKTGM 456
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 109 bits (273), Expect = 7e-28 Identities = 79/402 (19%), Positives = 168/402 (41%), Gaps = 17/402 (4%) Query: 23 FMAGMNVHVTSAALPEIEGALGATFEEGSWISTAYLVAEISMIPLTAWLVEVFSLRRVML 82 F + +N V + +LP+I +W++TA+++ + L + ++R++L Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 83 LGSLVFLLSSLSCALAPN-LSTLILIRVIQGASGAVLIPLSMQLILTELPSSRIPLGMAL 141 G ++ S+ + + S LI+ R IQGA A L M ++ +P L Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 142 FSLSNSVAQAAGPSIGGWLADAYSWRWIFLLQLLPGIALLAAVAWSIRPRDGDRERLRQA 201 ++ + GP+IGG +A W ++ L+ ++ I + + + R + Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKL---LKKEVRIK-GHF 199 Query: 202 DWLGIGAMVAGLGALQIVLEEGGRRDWFESGFIRTFAVLAVLALLLFVQRQLWGARPFIN 261 D GI M G+ + F + + +F +++VL+ L+FV+ PF++ Sbjct: 200 DIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVD 249 Query: 262 LRLLGSYNFGVSSLAMAVFGAATFGLVFLVPNYLSQLQGFNARQIGDSLILYGLVQLLL- 320 L + F + L + G V +VP + + + +IG +I G + +++ Sbjct: 250 PGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIF 309 Query: 321 APLLPRLMRWLNPKLLVAGGFAIMALGCWMGAHLNADAGRNVIIPSIVVRGIGQPLIMVA 380 + L+ P ++ G +++ ++ A + + IV G Sbjct: 310 GYIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGLSFTKTV 368 Query: 381 LSVLAVKGLDKAQAGSASALISMLRNLGGAIGTALLTQLVSL 422 +S + L + +AG+ +L++ L G A++ L+S+ Sbjct: 369 ISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 9e-04 Identities = 14/103 (13%), Positives = 31/103 (30%), Gaps = 6/103 (5%) Query: 87 RHDLPRDCRVVDVPPLLRQLIVAAMRIAPDYPPGGRDERVMELILDELRVLPILALHVPQ 146 R + + R + + + ++ + D L + + + Sbjct: 376 REIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAE 435 Query: 147 PVDPRLAALCRSLRAEPAADWSLGDAARRLGVSPRTLTRAFQR 189 P + L A A + AA LG++ TL + + Sbjct: 436 MEYPLI------LAALTATRGNQIKAADLLGLNRNTLRKKIRE 472
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 65.6 bits (160), Expect = 4e-14 Identities = 43/214 (20%), Positives = 75/214 (35%), Gaps = 39/214 (18%) Query: 79 RSYRLAVRQREAELEQARETLRQRDEQWRRRMQLAGAVSREEVANAGRALRIARARAEAA 138 R Y+ + Q E+E+ A+E + + ++ + LR Sbjct: 269 RVYKSQLEQIESEILSAKEEYQLVTQLFKNEIL--------------DKLRQTTDNIGLL 314 Query: 139 GAALDQARLDLRRSELRSPVDGYVTQLRVQ-PGDYAAAGRTNIFIV-DRRSFWVTGYFEE 196 L + + S +R+PV V QL+V G T + IV + + VT + Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQN 374 Query: 197 TKLRNVQVGAPATIKLMGFD----PLLDGHVASIGRGVADLNESRADSGLPQVSPNFSWI 252 + + VG A IK+ F L G V +I D+ Q Sbjct: 375 KDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN----------LDAIEDQRLGLV--- 421 Query: 253 RLAQRVPVRIELDRVPA---GVVLAAGMTGSVEV 283 V + IE + + + L++GM + E+ Sbjct: 422 ---FNVIISIEENCLSTGNKNIPLSSGMAVTAEI 452 Score = 47.5 bits (113), Expect = 3e-08 Identities = 18/114 (15%), Positives = 41/114 (35%), Gaps = 3/114 (2%) Query: 41 VSAQVIRIAPEVSGSVEAVFVADNQRVARGDPLYRIDPRSYRLAVRQREAELEQARETLR 100 S + I P + V+ + V + + V +GD L ++ + ++ L QAR + Sbjct: 92 HSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE-Q 150 Query: 101 QRDEQWRRRMQLAGAVSREEVANAGRALRIARARAEAAGAALDQARLDLRRSEL 154 R + R ++L E + +L + + +++ Sbjct: 151 TRYQILSRSIELNKL--PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQK 202
>cloacin#Cloacin signature. Length = 551 Score = 49.7 bits (118), Expect = 9e-09 Identities = 27/79 (34%), Positives = 30/79 (37%), Gaps = 5/79 (6%) Query: 197 GGDGGSDGGTKPGNGGGDDGSSGGGGGGGGGGNNPCQGHVGSDCGTTPGGDGSSGGDGDG 256 GGDG G +G G G GGG + G P G GS G G Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGS-----GWSSENNPWGGGSGSGIHWG 57 Query: 257 SGSSGGTGGDGGDGSGGGG 275 GS G GG G+ GG G Sbjct: 58 GGSGHGNGGGNGNSGGGSG 76 Score = 43.9 bits (103), Expect = 7e-07 Identities = 30/86 (34%), Positives = 33/86 (38%), Gaps = 7/86 (8%) Query: 182 GGDGGTGGDGGSNPPGGDGGSDGGTKPGNGGGDDGSSGGGGGGGGGGNNPCQGHVGSDCG 241 GGDG G + G G G G GG DGS G NNP G GS Sbjct: 3 GGDGRGHNTGAHSTSGNINGGPTGLGVG-GGASDGS------GWSSENNPWGGGSGSGIH 55 Query: 242 TTPGGDGSSGGDGDGSGSSGGTGGDG 267 G +GG SG GTGG+ Sbjct: 56 WGGGSGHGNGGGNGNSGGGSGTGGNL 81 Score = 41.2 bits (96), Expect = 5e-06 Identities = 29/77 (37%), Positives = 34/77 (44%), Gaps = 4/77 (5%) Query: 176 GDGPPPGGDGGTGGDGGSNPPGGDGGSD----GGTKPGNGGGDDGSSGGGGGGGGGGNNP 231 G G G G+G +NP GG GS GG+ GNGGG+ S GG G GG Sbjct: 26 GLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85 Query: 232 CQGHVGSDCGTTPGGDG 248 G +TPG G Sbjct: 86 APVAFGFPALSTPGAGG 102 Score = 39.3 bits (91), Expect = 2e-05 Identities = 18/55 (32%), Positives = 19/55 (34%) Query: 174 GPGDGPPPGGDGGTGGDGGSNPPGGDGGSDGGTKPGNGGGDDGSSGGGGGGGGGG 228 GP GG G N P G G G G G +G G GGG G Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGT 77 Score = 37.4 bits (86), Expect = 9e-05 Identities = 25/67 (37%), Positives = 29/67 (43%), Gaps = 9/67 (13%) Query: 218 SGGGGGGGGGGNNPCQGHV-GSDCGTTPGGDGSSGGD--------GDGSGSSGGTGGDGG 268 SGG G G G + G++ G G GG S G G GSGS GG G Sbjct: 2 SGGDGRGHNTGAHSTSGNINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSG 61 Query: 269 DGSGGGG 275 G+GGG Sbjct: 62 HGNGGGN 68 Score = 37.0 bits (85), Expect = 1e-04 Identities = 29/95 (30%), Positives = 34/95 (35%), Gaps = 13/95 (13%) Query: 182 GGDGGTGGDGGSNPPGGDGGSDGGTKPGNGGGDDGSSGGGGGGGGGGNNPCQGHVGSDCG 241 GG G G GG++ G G S G G G GGG G G GG N Sbjct: 22 GGPTGLGVGGGAS--DGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGN----------- 68 Query: 242 TTPGGDGSSGGDGDGSGSSGGTGGDGGDGSGGGGL 276 GG +GG+ + G G GGL Sbjct: 69 GNSGGGSGTGGNLSAVAAPVAFGFPALSTPGAGGL 103 Score = 35.1 bits (80), Expect = 5e-04 Identities = 18/59 (30%), Positives = 20/59 (33%) Query: 165 GSCAFGCDVGPGDGPPPGGDGGTGGDGGSNPPGGDGGSDGGTKPGNGGGDDGSSGGGGG 223 G G G DG + G G + GGS G GNG GS GG Sbjct: 23 GPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNL 81
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 24.9 bits (54), Expect = 0.031 Identities = 17/62 (27%), Positives = 25/62 (40%), Gaps = 4/62 (6%) Query: 7 LFRNASIATAGLAVANVSFAESLLDETTKGV----LAQASTDGGSVAKLVIAAVAVLVGL 62 + NA T A A V +L KG+ +AQ + G S + +A V L Sbjct: 257 ILSNADADTRTKAAAGVELTTKVLGNVGKGISQYIIAQRAAQGLSTSAAAAGLIASAVTL 316 Query: 63 AL 64 A+ Sbjct: 317 AI 318
>FLGPRINGFLGI#Flagellar P-ring protein signature. Length = 373 Score = 436 bits (1122), Expect = e-155 Identities = 168/366 (45%), Positives = 224/366 (61%), Gaps = 10/366 (2%) Query: 7 LLALAALLLAAGAAQAERLKDIASIQGVRTNQLIGYGLVVGLSGSGDQTTQTPFTLQTFN 66 AL L A R+KDIAS+Q R NQLIGYGLVVGL G+GD +PFT Q+ Sbjct: 13 FSALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGYGLVVGLQGTGDSLRSSPFTEQSMR 72 Query: 67 NMLAQFGIKVPANVGNVQLKNVAAVSVHADLPPFAKPGQPIDVTVSSIGNAKSLRGGSLL 126 ML GI G KN+AAV V A+LPPFA PG +DVTVSS+G+A SLRGG+L+ Sbjct: 73 AMLQNLGITTQG--GQSNAKNIAAVMVTANLPPFASPGSRVDVTVSSLGDATSLRGGNLI 130 Query: 127 MTPLKGIDGQVYAVAQGNLVVGGFDAEGRDGSKITVNVPSAGRIPAGATVERAVPSGFDQ 186 MT L G DGQ+YAVAQG L+V GF A+G D + +T V ++ R+P GA +ER +PS F Sbjct: 131 MTSLSGADGQIYAVAQGALIVNGFSAQG-DAATLTQGVTTSARVPNGAIIERELPSKFKD 189 Query: 187 GNSLTLNLNRPDFTTAKRIVDRINEL----LGPGVAHAVDGGSVRVSAPLDPNQRVDYLS 242 +L L L PDF+TA R+ D +N G +A D + V P ++ Sbjct: 190 SVNLVLQLRNPDFSTAVRVADVVNAFARARYGDPIAEPRDSQEIAVQKP-RVADLTRLMA 248 Query: 243 ILENLDVQPGEAVAKVIINSRTGTIVIGQNVKVSPAAVTHGSLTVSITEDPIVSQPGAFS 302 +ENL V+ + AKV+IN RTGTIVIG +V++S AV++G+LTV +TE P V QP FS Sbjct: 249 EIENLTVET-DTPAKVVINERTGTIVIGADVRISRVAVSYGTLTVQVTESPQVIQPAPFS 307 Query: 303 NGQTAVVPRSRVNAEEETKPMFKFGPGTTLDDIVRAVNQVGAAPSDLMAILEALKQAGAL 362 GQTAV P++ + A +E + G L +V +N +G ++AIL+ +K AGAL Sbjct: 308 RGQTAVQPQTDIMAMQEGSKVA-IVEGPDLRTLVAGLNSIGLKADGIIAILQGIKSAGAL 366 Query: 363 QADLIV 368 QA+L++ Sbjct: 367 QAELVL 372
>FLGLRINGFLGH#Flagellar L-ring protein signature. Length = 232 Score = 180 bits (459), Expect = 3e-59 Identities = 81/224 (36%), Positives = 112/224 (50%), Gaps = 13/224 (5%) Query: 12 IATALGGCVNPPPKPNDPYYAPVLPRTPLPAAQNNGAIYQAGF-----EQNLYDDRKAFR 66 + +L GC P P P P P NG+I+Q+ Q L++DR+ Sbjct: 15 LVLSLTGCAWIPSTPLVQGATSAQP-VPGPTPVANGSIFQSAQPINYGYQPLFEDRRPRN 73 Query: 67 VGDIITITLNEKTQASKKANSDIQKDSKTKMGLTSLFGSGMTTNNPIGGGDLSLSAEYGG 126 +GD +TI L E ASK ++++ +D KT G + G + E G Sbjct: 74 IGDTLTIVLQENVSASKSSSANASRDGKTNFGFDT---VPRYLQGLFGNARADV--EASG 128 Query: 127 SRDAKGDSQAGQSNSLTGSITVTVAEVLPNGILSVRGEKWMTLNTGNELVRIAGLVRADD 186 G A SN+ +G++TVTV +VL NG L V GEK + +N G E +R +G+V Sbjct: 129 GNTFNGKGGANASNTFSGTLTVTVDQVLVNGNLHVVGEKQIAINQGTEFIRFSGVVNPRT 188 Query: 187 IATDNTVSSTRVADARITYSGTGAFADASQPGWLDRFF--LSPL 228 I+ NTV ST+VADARI Y G G +A GWL RFF LSP+ Sbjct: 189 ISGSNTVPSTQVADARIEYVGNGYINEAQNMGWLQRFFLNLSPM 232
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.6 bits (105), Expect = 2e-07 Identities = 13/51 (25%), Positives = 25/51 (49%) Query: 209 NGLGTVAQNTLENSNVNVVEELVNMITTQRAYEMNSKVISTADQMLSFVTQ 259 N + ++ S VN+ EE N+ Q+ Y N++V+ TA+ + + Sbjct: 494 NVVTQLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544 Score = 39.6 bits (92), Expect = 9e-06 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 14/79 (17%) Query: 3 SALWVSKTGLSAQDMNLTTISNNLANVSTTGFKRDRAEFQDLLYQIRRQPGGQSTQDSEL 62 S + + +GL+A L T SNN+++ + G+ R + +S L Sbjct: 2 SLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTI--------------MAQANSTL 47 Query: 63 PSGLQLGTGVRVVGTQKIF 81 +G +G GV V G Q+ + Sbjct: 48 GAGGWVGNGVYVSGVQREY 66
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 44.9 bits (106), Expect = 5e-07 Identities = 17/49 (34%), Positives = 27/49 (55%) Query: 414 ALQSGALEASNVDISNELVNLIVHQRNYQANAKTIQTEDAVTQTIINLR 462 L + S V++ E NL Q+ Y ANA+ +QT +A+ +IN+R Sbjct: 498 QLSNQQQSISGVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR 546 Score = 41.1 bits (96), Expect = 8e-06 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 3/69 (4%) Query: 2 SFNIGLSGIQAASSGLNVTGNNIANAGTVGFKQSRAEFADVYAASVLGSGSNPQGSGVLL 61 N +SG+ AA + LN NNI++ G+ + A A S LG+G G+GV + Sbjct: 3 LINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQ--ANSTLGAGGW-VGNGVYV 59 Query: 62 SDVSQMFKQ 70 S V + + Sbjct: 60 SGVQREYDA 68
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 36.1 bits (83), Expect = 3e-05 Identities = 8/38 (21%), Positives = 20/38 (52%) Query: 107 NVNVVEEMADMISASRAFQTNAEMMNTAKQMMQKVLTL 144 VN+ EE ++ + + NA+++ TA + ++ + Sbjct: 508 GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINI 545 Score = 29.5 bits (66), Expect = 0.004 Identities = 15/54 (27%), Positives = 25/54 (46%), Gaps = 2/54 (3%) Query: 4 ASVFNIAGSGMSAQSTRLNTVASNIANAETVSSSVDKTYRARHPVFSTMFQQAQ 57 +S+ N A SG++A LNT ++NI++ + T A ST+ Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMA--QANSTLGAGGW 52
>PF04183#IucA / IucC family Length = 580 Score = 29.8 bits (67), Expect = 0.016 Identities = 13/67 (19%), Positives = 27/67 (40%), Gaps = 5/67 (7%) Query: 214 EGGGEFLMRGRPMFEHASQTLVRIAGEMLAAHELTLD-DIDHVICHQPNLRILDAVQEQL 272 +G + P + Q + + + +A L D H + LR + + +L Sbjct: 444 QGDMRLVKEEFPEMDSLPQEVRDVTSRL-SADYLIHDLQTGHFVTV---LRFISPLMVRL 499 Query: 273 GIPQHKF 279 G+P+ +F Sbjct: 500 GVPERRF 506
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 791 bits (2044), Expect = 0.0 Identities = 282/863 (32%), Positives = 443/863 (51%), Gaps = 47/863 (5%) Query: 12 LSVYSRSSCLMALGLALPAVTFAVEFNAEFLNNEGGAPVELKYFENGNSVSPGTYSVDIH 71 + R A P + + FN FL ++ A +L FENG + PGTY VDI+ Sbjct: 24 AGFFVRLFVACAFAAQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIY 83 Query: 72 LNQIMIRREDVVFSADPETGSVRPVVRIGLLKEIGVDIARLTRDKLIPDNLENNTPLNVA 131 LN + DV F+ + P + L +G++ A ++ L+ D+ + + Sbjct: 84 LNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADD----ACVPLT 139 Query: 132 ELIPGASIEFDVNSLSLLVSIPQLYVQRHSRGYVDPSLWDDGVTALFSNYQANFTRNTN- 190 +I A+ + DV L ++IPQ ++ +RGY+ P LWD G+ A NY + N Sbjct: 140 SMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNR 199 Query: 191 FGQNSDYRYLGLRNGFNLFGWRLRNDSSLS-----GGTGMRNKFSSNRTYVERDIRALKG 245 G NS Y YL L++G N+ WRLR++++ S +G +NK+ T++ERDI L+ Sbjct: 200 IGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRS 259 Query: 246 TLSLGELYTSAQGDAFESVRMRGVQLQSDIGMLPDNEISYTPVVRGIAETNATVEVSQNG 305 L+LG+ YT GD F+ + RG QL SD MLPD++ + PV+ GIA A V + QNG Sbjct: 260 RLTLGDGYTQ--GDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNG 317 Query: 306 FVIYSTNVPPGAFEITDIYPSGSNGDLEVKIIEADGRQRSFKQSYSYLPVMTRKGNLRYG 365 + IY++ VPPG F I DIY +G++GDL+V I EADG + F YS +P++ R+G+ RY Sbjct: 318 YDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYS 377 Query: 366 LAAGEYHNDG--QPSVNLLQGSAVYGLSDRVTGFGGLLAAEKYNATNLGLGFNT-PLGGF 422 + AGEY + Q Q + ++GL T +GG A++Y A N G+G N LG Sbjct: 378 ITAGEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGAL 437 Query: 423 SADVTHSQSRTRRGGRNQGQSLRLLYSKTINATETSFTVVGYRYSTEGYRTLSQH----- 477 S D+T + S ++ GQS+R LY+K++N + T+ +VGYRYST GY + Sbjct: 438 SVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRM 497 Query: 478 ----------IDDMSEESYLYGSSSSRQKSRIDLTVNQTLFRRSSLYLTAGETTYWNRPG 527 + + + Y + + ++ ++ LTV Q L R S+LYL+ TYW Sbjct: 498 NGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSN 557 Query: 528 SSRRVQFGFSSGIKRASYSLAVSRTQETGSFGRSDTQFTASVSIPLGG--------SARS 579 + Q G ++ + +++L+ S T+ GR D +V+IP R Sbjct: 558 VDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGR-DQMLALNVNIPFSHWLRSDSKSQWRH 616 Query: 580 SQVYANAVSSQHGDSSLNTGISGYLDEANAFNYSAQANYSKDG----GNSGSVGLGWDTS 635 + + +G + G+ G L E N +YS Q Y+ G G++G L + Sbjct: 617 ASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGG 676 Query: 636 KAKLSANYSQGRDNKQINLGASGSVVVHSGGVTFGQPVGETFGLVEVPEVGGVGLDGYSS 695 + YS D KQ+ G SG V+ H+ GVT GQP+ +T LV+ P ++ + Sbjct: 677 YGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTG 736 Query: 696 VRTDGRGYAVLPYMQPYRYNWVNLDTNTLGSDTEISDSTQMAVPTRGAVIAKRFSAESGR 755 VRTD RGYAVLPY YR N V LDTNTL + ++ ++ VPTRGA++ F A G Sbjct: 737 VRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGI 796 Query: 756 RVQFDLSMDSGGKIPFGAQAYDKEERVVGMVDNLSRLLVFGIEDQGRLSIRWSDG---SC 812 ++ L+ + +PFGA + + G+V + ++ + G+ G++ ++W + C Sbjct: 797 KLLMTLTHN-NKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENAHC 855 Query: 813 SVDYQLPPRNKDLTYERVALSCR 835 +YQLPP ++ +++ CR Sbjct: 856 VANYQLPPESQQQLLTQLSAECR 878
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 31.7 bits (72), Expect = 0.003 Identities = 10/53 (18%), Positives = 19/53 (35%) Query: 69 QLQQMQDELARLRGTLEEQQNQIQQLKQESLERYQDLDRRIAGGGAPAAQNSA 121 + + +EL + LE+ +++I K+E Q I N Sbjct: 260 KYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 116 bits (291), Expect = 6e-34 Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 12/112 (10%) Query: 68 YFEYDSSDLKPEAMRALDVHA---KDLKGSGQRVVLEGHTDERGTREYNMALGERRAKAV 124 F ++ + LKPE ALD +L VV+ G+TD G+ YN L ERRA++V Sbjct: 222 LFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSV 281 Query: 125 QRYLVLQGVSPAQLELVSYGKERPVATGHDEQS---------WAQNRRVELK 167 YL+ +G+ ++ G+ PV + A +RRVE++ Sbjct: 282 VDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIE 333
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 49.3 bits (117), Expect = 1e-08 Identities = 36/204 (17%), Positives = 71/204 (34%), Gaps = 21/204 (10%) Query: 54 QLKSKSQATTQTNQKIAGEAKKTASKQYE-----VEQLEQKKLEQQKLEQQKLEQQQVAA 108 Q + TT N + + + +++ + E +Q + Sbjct: 990 QTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESK 1049 Query: 109 AKAAEQKKADEARKAEAQKAAEAKKADEAKKAAEAKAAEQKKQADIAKKRAEDEAKKKAA 168 ++ A E + A EAK +A + ++A ++ E K+ Sbjct: 1050 TVEKNEQDATETTAQNREVAKEAKSNVKA----------NTQTNEVA--QSGSETKETQT 1097 Query: 169 EDAKKKAAEDAKKKAAEEAKKKAAAEAAKKKAAVEAAKKKAAAAAAAARKAAEDKKAQAL 228 + K+ A + ++KA E +K E K + V ++++ A A E+ + Sbjct: 1098 TETKETATVEKEEKAKVETEKT--QEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNI 1155 Query: 229 AELLS--DTTERQQALADEVGSEV 250 E S +TT + A E S V Sbjct: 1156 KEPQSQTNTTADTEQPAKETSSNV 1179
>60KDINNERMP#60kDa inner membrane protein signature. Length = 548 Score = 29.1 bits (65), Expect = 0.017 Identities = 17/72 (23%), Positives = 28/72 (38%), Gaps = 13/72 (18%) Query: 12 WSLISNASIVVQLVMLTLVAASVTSWIMIFQRGNAMRAAKKALDAFEERFWS-----GID 66 +S+I + +V+ +M L A TS MR + + A ER + Sbjct: 356 FSIII-ITFIVRGIMYPLTKAQYTSM-------AKMRMLQPKIQAMRERLGDDKQRISQE 407 Query: 67 LSKLYRQAGSNP 78 + LY+ NP Sbjct: 408 MMALYKAEKVNP 419
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 31.6 bits (71), Expect = 0.009 Identities = 31/117 (26%), Positives = 51/117 (43%), Gaps = 23/117 (19%) Query: 212 YYQIAKCFRDEDLRADRQPEFTQIDIETSFLDESDIIGITEKMVRQLFKEVL-------D 264 YY+I K + + D+ + +++ S D+SD ++ + Q FKE L D Sbjct: 170 YYEIGKGISLDIISKDKSLDPEFLNLIKSLSDDSD---SSDLLFSQKFKEKLELNNKSID 226 Query: 265 VEF-----DEFPHMPFEEAMRRYGSDKPDLRIPLEL-----VDVADQLKEVEFKVFS 311 + F EF H F A Y + PD R LEL + ++L++ F+ S Sbjct: 227 INFIKENLTEFQHA-FSLAFSYYFA--PDHRTVLELYAPDMFEYMNKLEKGGFEKIS 280
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 157 bits (398), Expect = 3e-52 Identities = 50/145 (34%), Positives = 72/145 (49%) Query: 11 DRAAIAEGLSRLLADTYTLYLKTHNFHWNVTGPMFNTLHLMFEGQYTELAVAVDDIAERI 70 ++ + L+ L++ + LY K H FHW V GP F TLH FE Y A VD IAER+ Sbjct: 9 NQTLVENSLNTQLSNWFLLYSKLHRFHWYVKGPHFFTLHEKFEELYDHAAETVDTIAERL 68 Query: 71 RALGFPAPGTYAAYARLSSIKEEEGVPEAEEMIRQLVQGQEAVVRTARSIFPLLDKVSDE 130 A+G T Y +SI + A EM++ LV + + ++ + L ++ D Sbjct: 69 LAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVNDYKQISSESKFVIGLAEENQDN 128 Query: 131 PTADLLTQRMQVHEKTAWMLRSLLA 155 TADL ++ EK WML S L Sbjct: 129 ATADLFVGLIEEVEKQVWMLSSYLG 153
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.1 bits (67), Expect = 0.031 Identities = 10/54 (18%), Positives = 22/54 (40%) Query: 208 HEFHVLANSGEDDIVFSDSSDYAANIEKAEAVPRESARGSATEDMRLVDTPNTK 261 V E + + DYA N E+++ V E +G + + + + + + Sbjct: 138 ASRFVFEKKRETPKLIINIKDYAINSEQSKEVYYEIGKGISLDIISKDKSLDPE 191
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 102 bits (256), Expect = 5e-28 Identities = 40/133 (30%), Positives = 67/133 (50%), Gaps = 15/133 (11%) Query: 115 MPGNITFATDSANIAPSFYAPLNNLANSFKQYN--QNTIEIVGYTDSTGSRQHNMDLSQR 172 + ++ F + A + P A L+ L + + ++ ++GYTD GS +N LS+R Sbjct: 217 LKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSER 276 Query: 173 RAQSVAGYLTALGVDGTRLSTRGMGPDQPIASNSTADGR---------AQNRRVEVNLRP 223 RAQSV YL + G+ ++S RGMG P+ N+ + + A +RRVE+ ++ Sbjct: 277 RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKG 336 Query: 224 VPGAQGPAQTQPQ 236 + TQPQ Sbjct: 337 IK----DVVTQPQ 345
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 53.5 bits (128), Expect = 6e-11 Identities = 28/193 (14%), Positives = 71/193 (36%), Gaps = 13/193 (6%) Query: 39 RTNIQLAAIPVFTRKGIAETTVNDLLEAARVSRRTFYKYFAGKLEVLESIYHSAVQLLLA 98 R +I A+ +F+++G++ T++ ++ +AA V+R Y +F K ++ I+ + + Sbjct: 13 RQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGE 72 Query: 99 RFGGLRSEAGSD-EDWLRAMVSLFFDYHL---AVGPIIRMMQEEALHAGS--PLAAHRQR 152 +++ D LR ++ + + ++ ++ + G + ++ Sbjct: 73 LELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRN 132 Query: 153 AHLKIIELWAERLG---AQGAAHDALTYRVLIWAMEAASLELLN----ASDPLELPRVKR 205 L+ + + L L R M L+ A +L + R Sbjct: 133 LCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLKKEAR 192 Query: 206 VLGDLLVGTLCPR 218 +L+ Sbjct: 193 DYVAILLEMYLLC 205
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.002 Identities = 30/155 (19%), Positives = 58/155 (37%), Gaps = 7/155 (4%) Query: 5 LAANPTQRYRWVILLIATFAQACACFFVQGIGAI-----AVFIQNDLQLSSLQIGLLVSA 59 A NP +RW + A F +Q +G + +F ++ + IG+ ++A Sbjct: 195 EALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAA 254 Query: 60 AQLVPIVG-LLVAGELLDRYSERLVVGLGTLIVALALCASLWATDYLTILLFLVVVGAGY 118 ++ + ++ G + R ER + LG + +AT +V++ +G Sbjct: 255 FGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG- 313 Query: 119 STAQPGGSKSVSRWFAKTQLGFAMGIRQAGLPLGG 153 P +SR + + G G A L Sbjct: 314 GIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTS 348
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 378 bits (972), Expect = e-131 Identities = 187/406 (46%), Positives = 253/406 (62%), Gaps = 3/406 (0%) Query: 1 MQTFRYEAADAQGRIETGTLEADSQRGALGQLRARGLTPLEVREQAGGGTGQGAGALFAP 60 M + Y+A DAQG+ GT EADS R A LR RGL PL V E G G+ L Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 61 R---LSDGDLAWATRQLASLLAASLPLEAALSATLDQAERKHIAQTLSAVRSDVRGGMRL 117 R LS DLA TRQLA+L+AAS+PLE AL A Q+E+ H++Q ++AVRS V G L Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 118 ADALAARPRDFPEIYRALVAAGEESGDLAQVMERLADYIEERNALRGKILTAFIYPAVVG 177 ADA+ P F +Y A+VAAGE SG L V+ RLADY E+R +R +I A IYP V+ Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 178 VVSIGIVIFLLGYVVPQVVSAFSQARQDLPALTRAMLQASDFVRAWGWLCAGAIGSAYWG 237 VV+I +V LL VVP+VV F +Q LP TR ++ SD VR +G A+ + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 238 WRLYLRDPQARLGWHRRVLRLPLLGRFVLGVNTARFASTLAILGSAGVPLLRALDAARQT 297 +R+ LR + R+ +HRR+L LPL+GR G+NTAR+A TL+IL ++ VPLL+A+ + Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 298 LANDCLAQAVEEATAQVREGVSLASALRTRQVFPPILTHLIASGEKTGALPPMLDRAAQT 357 ++ND + AT VREGVSL AL +FPP++ H+IASGE++G L ML+RAA Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 358 LSRDIERRAMGMTALLEPLMIVVMGGVVLTIVMAVLMPIIEMNQLV 403 R+ + L EPL++V M VVL IV+A+L PI+++N L+ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 255 bits (654), Expect = 7e-77 Identities = 151/571 (26%), Positives = 257/571 (45%), Gaps = 50/571 (8%) Query: 230 PGNNTVVVTDYAENLDRVAGIIASIDIPSASD---TDVVPIQNGIAVDIASTVSELLDSQ 286 NN V+ +++ A +AS P D T VVP+ N A D+A + +L D+ Sbjct: 94 NMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPLLRQLNDNA 153 Query: 287 GSGGAEQGQKTVVLADPRSNSIVIRSPSPERTQLARDLIGKLDSVQSNPGNLHVVYLRNA 346 G G +VV +P SN +++ + +L ++ ++D+ ++ V L A Sbjct: 154 GVG-------SVVHYEP-SNVLLMTGRAAVIKRL-LTIVERVDNAGDR--SVVTVPLSWA 202 Query: 347 QATRLAQALRGLITGDSGGEGNE--------GDQQRARLSGGG---------MLGGGNSG 389 A + + + L S ++ A L G M+ + Sbjct: 203 SAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQLDRQ 262 Query: 390 TGSQGLGSSGNTTGSGSSGLGGSNRSGGAYGAMGSGQGGAGPGAMGEENSAFSAGGVTVQ 449 +QG + +S L Q A+ + + ++ Sbjct: 263 QATQGNTKVIYLKYAKASDLVEVLTGIS-STMQSEKQAAKPVAALDK--------NIIIK 313 Query: 450 ADATTNTLLISAPEPLYRNLREVIDLLDQRRAQVVIESLIVEVSEDDSSEFGIQWQAGNL 509 A TN L+++A + +L VI LD RR QV++E++I EV + D GIQW N Sbjct: 314 AHGQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNA 373 Query: 510 GGNGVFG-GVNFGQSALNTAGKNTIDVLPKGLNIGLVDGTVDIPGIGKILDLKVLARALK 568 G G+ + N + L L G + + +L AL Sbjct: 374 GMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQG-NWAMLLTALS 432 Query: 569 SRGGTNVLSTPNLLTLDNESASIMVGQTIPFVSGQYVTDGGGTSNNPFQTIQREDVGLKL 628 S ++L+TP+++TLDN A+ VGQ +P ++G T G N F T++R+ VG+KL Sbjct: 433 SSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGD----NIFNTVERKTVGIKL 488 Query: 629 NIRPQISEGGTVKLDVYQEVSSVDERASTAA---GVVTNKRAIDTSILLDDGQIMVLGGL 685 ++PQI+EG +V L++ QEVSSV + AS+ + G N R ++ ++L+ G+ +V+GGL Sbjct: 489 KVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGL 548 Query: 686 LQDNVQDNTDGVPGLSSLPGVGSLFRYQKRSRTKTNLMVFLRPYIVRDAAAGRSITLNRY 745 L +V D D VP L +P +G+LFR + +K NLM+F+RP ++RD R + +Y Sbjct: 549 LDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQY 608 Query: 746 DFIRRAQ-QRVQPRHDWSVGDMQAPVLPPAQ 775 AQ ++ ++ ++ + + P Q Sbjct: 609 TAFNDAQSKQRGKENNDAMLNQDLLEIYPRQ 639 Score = 159 bits (404), Expect = 6e-43 Identities = 72/276 (26%), Positives = 127/276 (46%), Gaps = 7/276 (2%) Query: 87 VAPVSATAAELGEQPVSLNFVDTEVEAVVRALSRATGRQFLVDPRVKGKLTLVSEGQVPA 146 A + A E +F T+++ + +S+ + ++DP V+G +T+ S + Sbjct: 17 FAALLFRPAAAEEFSA--SFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNE 74 Query: 147 RTAYRMLTSALRMQGFSVVDVD-GVSQVVPEADAKLLGGPVYGADRPA-ANGMVTRTFRL 204 Y+ S L + GF+V++++ GV +VV DAK PV P + +VTR L Sbjct: 75 EQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPL 134 Query: 205 RYENAVNLIPVLRPIVAQNNPINA--YPGNNTVVVTDYAENLDRVAGIIASIDIPSASDT 262 A +L P+LR + + Y +N +++T A + R+ I+ +D Sbjct: 135 TNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSV 194 Query: 263 DVVPIQNGIAVDIASTVSELLDSQGSGGAEQGQKTVVLADPRSNSIVIRSPSPERTQLAR 322 VP+ A D+ V+EL V+AD R+N++++ P Q Sbjct: 195 VTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGE-PNSRQRII 253 Query: 323 DLIGKLDSVQSNPGNLHVVYLRNAQATRLAQALRGL 358 +I +LD Q+ GN V+YL+ A+A+ L + L G+ Sbjct: 254 AMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGI 289 Score = 50.7 bits (121), Expect = 2e-08 Identities = 44/299 (14%), Positives = 103/299 (34%), Gaps = 56/299 (18%) Query: 194 ANGMVTRTFRLRYENAVNLIPVLRPI----------VAQNNPINAYPGNNTVVVTDYAEN 243 A T L + +A +++ ++ + + + A N V+V+ + Sbjct: 189 AGDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNS 248 Query: 244 LDRVAGIIASIDIPSAS--DTDVVPIQNGIAVDIASTVSELL-----DSQGSGGAEQGQK 296 R+ +I +D A+ +T V+ ++ A D+ ++ + + Q + K Sbjct: 249 RQRIIAMIKQLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDK 308 Query: 297 TV-VLADPRSNSIVIRSPSPERTQLARDLIGKLDSVQSNPGNLHVVYLRNAQATRLAQAL 355 + + A ++N++++ + P+ +I +LD +R Q + Sbjct: 309 NIIIKAHGQTNALIVTAA-PDVMNDLERVIAQLD-------------IRRPQV-----LV 349 Query: 356 RGLITGDSGGEGNEGDQQRARLSGGGMLG--GGNSGTGSQGLGSSGNTTGSGSSGLGGSN 413 +I +G LG N G +SG + +G N Sbjct: 350 EAIIAEVQDADGLN-------------LGIQWANKNAGMTQFTNSGLPISTAIAGANQYN 396 Query: 414 RSGGAYGAMGSGQGGAGPGAMGEENSAFSAGGVTVQA-DATTNTLLISAPEPLYRNLRE 471 + G ++ S A G + + + A ++T +++ P + + E Sbjct: 397 KDGTVSSSLASALSSFNGIAAGFYQGNW---AMLLTALSSSTKNDILATPSIVTLDNME 452 Score = 44.1 bits (104), Expect = 2e-06 Identities = 20/84 (23%), Positives = 35/84 (41%), Gaps = 16/84 (19%) Query: 190 DRPAANGMVTRTFRLRYENAVNLIPVLR----------------PIVAQNNPINAYPGNN 233 DR A T+ L+Y A +L+ VL + +N I A+ N Sbjct: 260 DRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDKNIIIKAHGQTN 319 Query: 234 TVVVTDYAENLDRVAGIIASIDIP 257 ++VT + ++ + +IA +DI Sbjct: 320 ALIVTAAPDVMNDLERVIAQLDIR 343
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 167 bits (425), Expect = 1e-56 Identities = 63/142 (44%), Positives = 87/142 (61%), Gaps = 6/142 (4%) Query: 11 KGHRGQRGFTLIEIMVVVVILGILAAMVVPKVLDRPDQARATAARQDISGLMQALKLYRL 70 + QRGFTL+EIMVV+VI+G+LA++VVP ++ ++A A DI L AL +Y+L Sbjct: 2 RATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 71 DQGRYPSQAQGLKVLAERP-ADASASNWRS--YLERLPNDPWGKPYQYLNPGVNGEIDVF 127 D YP+ QGL+ L E P A+N+ Y++RLP DPWG Y +NPG +G D+ Sbjct: 62 DNHHYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLL 121 Query: 128 SLGADGQPGGEGINADIGSWQL 149 S G DG+ G E DI +W L Sbjct: 122 SAGPDGEMGTED---DITNWGL 140
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 31.0 bits (70), Expect = 6e-04 Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 3/62 (4%) Query: 8 RGFTLIEVLVALAIVAIALAAAIRAVGLMTDGNGLLRDKSLA-LLAAESRLAELRLGVGA 66 RGFTL+E++V IV I + A++ LM + + K+++ ++A E+ L +L Sbjct: 8 RGFTLLEIMV--VIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHH 65 Query: 67 AP 68 P Sbjct: 66 YP 67
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 49.2 bits (117), Expect = 3e-10 Identities = 30/129 (23%), Positives = 46/129 (35%), Gaps = 7/129 (5%) Query: 5 RQGGFTLIELMVVLVIVGIATAAISLSARPDPTGLLRQDAARLARLLEIAQGEARVRGTP 64 RQ GFTL+E+M++L+++G++ + L+ Q AR L Q G Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQF 61 Query: 65 ILWQPSAKGYRFSPQAYRGKTDAFAADTELRARDWQAAPLRVSVRPPRPVLLDAEWIGAP 124 ++F R D AD W PLR V G Sbjct: 62 FGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWL--PLR-----AGRVATSGSIAGGK 114 Query: 125 LRITLSDGQ 133 L + + G+ Sbjct: 115 LNLAFAQGE 123
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.2 bits (73), Expect = 6e-04 Identities = 18/60 (30%), Positives = 32/60 (53%), Gaps = 3/60 (5%) Query: 12 RRQAGFTLIEVMVAIMLMAIV-SLMAWRGLDSIARASAHLEDSTEQGAALLRALNQLERD 70 +Q GFTL+E+MV I+++ ++ SL+ + + +A S AL AL+ + D Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVS--DIVALENALDMYKLD 62
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 3e-06 Identities = 39/231 (16%), Positives = 75/231 (32%), Gaps = 27/231 (11%) Query: 628 DQEQVRAEQSLERLRQTLAGLREGYSSQRERLNQSRQEQQELTGQLAALDR-QLDQWTLP 686 + E VR L +L G + L Q+R EQ +++ +L + LP Sbjct: 114 EGESVRKGDVLLKLTAL--GAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 687 EELRLLQPSAQLEWLAQRLDDLAGQRQQCQRDFDRLIARQRQTQQLQQELRAAETILQQR 746 +E S + L ++ Q Q Q + L + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIK------------EQFSTWQNQKYQKELNLDK----KRAE 215 Query: 747 QQALTEQRQRYEHLQQQVEEDSQQLRPLLSDEHWQRWQADPLRTFQALGESIEQRRQQQA 806 + + + RYE+L + + LL + + L E++ + R ++ Sbjct: 216 RLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAV--LEQENKYVEAVNELRVYKS 273 Query: 807 RLQQIEQRLQELKQRCDESSWQLKQSDEQRNEARQAEERAQAELAELNGRL 857 +L+QIE + K+ + +NE + + L L Sbjct: 274 QLEQIESEILSAKEE------YQLVTQLFKNEILDKLRQTTDNIGLLTLEL 318 Score = 37.1 bits (86), Expect = 4e-04 Identities = 24/178 (13%), Positives = 59/178 (33%), Gaps = 13/178 (7%) Query: 878 AQAAQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNL 937 Q ++E + P L +E + E + + +++F Q ++ Q L Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQN-----QKYQKEL 207 Query: 938 DDSRLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAER---QAQLLQHRRQRPETDRE 994 + + A + ++ + + + +L ++ + +L+ + E E Sbjct: 208 NLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNE 267 Query: 995 -----ALEDNLRQQRERLAASEQAYLDTYSQLQADNQRREQSQALLAELERARAEFRR 1047 + + + + Q + D R+ L LE A+ E R+ Sbjct: 268 LRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQ 325 Score = 36.3 bits (84), Expect = 7e-04 Identities = 24/164 (14%), Positives = 63/164 (38%), Gaps = 11/164 (6%) Query: 881 AQSAVETLQAPLDSLREEQLRLAEALEHLQQQRQRQQDEFQRLQADWQAWRERQDNLDDS 940 A++ Q+ L R EQ R R + ++ L+ + + + + Sbjct: 132 AEADTLKTQSSLLQARLEQTRYQILS------RSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 941 RLDALLGLSEEQATQWREQLQRLQEEITRQQTLEAERQAQLLQHRRQRPETDREALEDNL 1000 RL +L+ +EQ + W+ Q + + + +++ A++ ++ ++ L+D Sbjct: 186 RLTSLI---KEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS-RVEKSRLDD-F 240 Query: 1001 RQQRERLAASEQAYLDTYSQLQADNQRREQSQALLAELERARAE 1044 + A ++ A L+ ++ ++ L ++E Sbjct: 241 SSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILS 284 Score = 35.2 bits (81), Expect = 0.001 Identities = 19/166 (11%), Positives = 56/166 (33%), Gaps = 33/166 (19%) Query: 656 RERLNQSRQEQQELTGQLAALDRQLDQWTLPEELRLLQPSAQLEWLAQRLDDLAGQRQQC 715 +E+ + + ++ + L + T+ + + RLDD + + Sbjct: 192 KEQFSTWQNQKYQKELNLDKKRAERL--TVLARINRYE--NLSRVEKSRLDDFSSLLHKQ 247 Query: 716 QRDFDRLIARQRQTQQLQQELRAAETILQQRQQALTEQRQRYEHLQQQVEEDSQQLRPLL 775 ++ ++ + + ELR ++ L+Q + + ++ Y+ + Q + Sbjct: 248 AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKN--------- 298 Query: 776 SDEHWQRWQADPLRTFQALGESIEQRRQQQARLQQIEQRLQELKQR 821 E +++ RQ + + L + ++R Sbjct: 299 --------------------EILDKLRQTTDNIGLLTLELAKNEER 324 Score = 32.9 bits (75), Expect = 0.007 Identities = 27/214 (12%), Positives = 57/214 (26%), Gaps = 10/214 (4%) Query: 253 QALRRLEGQQQWFTEEQRLLQSCEHAQGQLAEARQAWDALATERETLQWLERLAPVRGLI 312 L +L E L Q +L + R + + E L L+ Sbjct: 122 DVLLKLTALG---AEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQN 178 Query: 313 ERLKQLEQELRHSEQQQRQRTEQQAAGAERLQGLQARLQEARERQAQADNHLRQAQAPLR 372 +++ + ++Q Q+ L +A R N + Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARI----NRYENLSRVEK 234 Query: 373 EAFQLESEARRLERTLAERQELHRQSNQRHAQQSDAARQL-DMEQQRHVAEQAQLQAALR 431 +L+ + L + + + Q N+ ++ +EQ A+ + L Sbjct: 235 S--RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV 292 Query: 432 DSQALAALGDAWATHQGQLAAFVQRRQRALESQA 465 + D + + E Q Sbjct: 293 TQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQ 326 Score = 30.6 bits (69), Expect = 0.049 Identities = 30/210 (14%), Positives = 59/210 (28%), Gaps = 14/210 (6%) Query: 120 ADGALQKSQQSLQDLETQQMLAANKKSEFREQLEQKL-------GLNFAQFTRAVLLAQS 172 AD +S LE + ++ E + E KL ++ + R L + Sbjct: 134 ADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKE 193 Query: 173 EFSAFLKASDNDRGALLEKLTDTGLYSQLSKAAYQRASQADEQRKQLEQ-RLEGSLPL-- 229 +FS + L +K + + + + ++ Sbjct: 194 QFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHA 253 Query: 230 ---AEQARAGLEAALESHAQARLQEQQALRRLEGQQQWFTEEQRLLQSCEHAQGQLAEAR 286 E L + Q + + + + Q T+ + + Q Sbjct: 254 VLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTD-NIG 312 Query: 287 QAWDALATERETLQWLERLAPVRGLIERLK 316 LA E Q APV +++LK Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLK 342
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 28.3 bits (63), Expect = 0.046 Identities = 17/90 (18%), Positives = 33/90 (36%), Gaps = 14/90 (15%) Query: 94 GVAQG-INPFTHGSAKHTDVMKTEGLKQALDKYGFDAAFGGARRDEEKSRAKERVYSFRD 152 + P HGSAK G+ ++ F + + +++ F Sbjct: 207 RFHNCSLFPVYHGSAK-----NNIGIDNLIE--VITNKFYSS---THRGQSELCGKVF-- 254 Query: 153 SKHRWDPKNQRPELWNIYNGKVKKGESIRV 182 K + K QR +Y+G + +S+R+ Sbjct: 255 -KIEYSEKRQRLAYIRLYSGVLHLRDSVRI 283
>V8PROTEASE#V8 serine protease family signature. Length = 336 Score = 60.4 bits (146), Expect = 3e-12 Identities = 33/163 (20%), Positives = 52/163 (31%), Gaps = 35/163 (21%) Query: 118 LLTNNHVTAGADQIIVALR------------DGRETIAQLVGSDPETDLAVLKIDL---- 161 LLTN HV AL+ +G T Q+ E DLA++K Sbjct: 114 LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEGDLAIVKFSPNEQN 173 Query: 162 ----KNLPAMTLGRSDGIRTGDVCLAIGNPFGVGQTVTMGIISATGRNQLGLNTYEDFIQ 217 + + T+ + + G P TM + G+ L +Q Sbjct: 174 KHIGEVVKPATMSNNAETQVNQNITVTGYPGD-KPVATMW--ESKGK-ITYLKGE--AMQ 227 Query: 218 TDAAINPGNSGGALVDAAGNLIGINTAIFSKSGGSQGIGFAIP 260 D + GNSG + + +IGI+ G+ Sbjct: 228 YDLSTTGGNSGSPVFNEKNEVIGIHWG---------GVPNEFN 261
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 29.8 bits (67), Expect = 0.012 Identities = 16/64 (25%), Positives = 27/64 (42%), Gaps = 11/64 (17%) Query: 40 CGFHAGDPLTMRRAVELAVR----HGVSIG------AHPAYPDLSGFGRRSLAC-SAEEV 88 CG AGD + + + L + SI + +L F +++L +AEEV Sbjct: 503 CGEMAGDEVAIPLLLGLGLDEFSMSATSILPARSQLLKLSKEELKPFAQKALMLDTAEEV 562 Query: 89 HAMV 92 +V Sbjct: 563 EQLV 566
>SECYTRNLCASE#Preprotein translocase SecY subunit signature. Length = 437 Score = 32.0 bits (73), Expect = 0.006 Identities = 15/63 (23%), Positives = 25/63 (39%) Query: 114 SEYFSQYFNPWMTLGLVLYSLVAILLWRRLRPVYLPRFSALPVAVLLIVATIGYPFYKQL 173 +EY S N G + L+A++ L + +LI+ +G KQ+ Sbjct: 364 AEYLSYVLNRITWPGSLYLGLIALVPTMALVGFGASQNFPFGGTSILIIVGVGLETVKQI 423 Query: 174 VSQ 176 SQ Sbjct: 424 ESQ 426
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.020 Identities = 23/141 (16%), Positives = 45/141 (31%), Gaps = 4/141 (2%) Query: 75 QVEDGQRVEPNQMLFQLKGP-ARALLTGERSALNFLQLLSGTATRSQHYADLVAGTAVKL 133 V++G+ V +L +L A A +S+L +L TR Q + + + Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL---EQTRYQILSRSIELNKLPE 167 Query: 134 LDTRKTLPGLRLAQKYAVTCGGCHNHRIGLYDAFLIKENHIAACGGIDRAIAEARRIAPG 193 L ++++ + + + ++ +R AR Sbjct: 168 LKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYE 227 Query: 194 KPVEVEVENLDELRQALEAGA 214 VE LD+ L A Sbjct: 228 NLSRVEKSRLDDFSSLLHKQA 248
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 53.0 bits (127), Expect = 1e-11 Identities = 20/54 (37%), Positives = 35/54 (64%) Query: 1 MKAQKGFTLIELMIVVAIIGILAAIAIPQYQDYTARTQVTRAVSEVSALKTAAE 54 Q+GFTL+E+M+V+ IIG+LA++ +P + +AVS++ AL+ A + Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALD 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 32.9 bits (75), Expect = 2e-04 Identities = 12/47 (25%), Positives = 26/47 (55%) Query: 4 RSQRALTLTELLFALVLLGILGSLALPGMAAWLDGNRQRSVLHELSA 50 QR TL E++ +V++G+L SL +P + + ++ + ++ A Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVA 51
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 40.6 bits (95), Expect = 5e-07 Identities = 14/45 (31%), Positives = 30/45 (66%) Query: 8 TGFTLIELLIIVVLLAIMASFAIPNFKQLTERNELQSAAEELNAM 52 GFTL+E+++++V++ ++AS +PN E+ + Q A ++ A+ Sbjct: 8 RGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVAL 52
>PilS_PF08805#PilS N terminal Length = 185 Score = 30.3 bits (68), Expect = 0.003 Identities = 11/58 (18%), Positives = 24/58 (41%) Query: 3 LKSRHRSLHQSGFSMIEVLVALLLISIGVLGMIAMQGKTIQYTADSVERNKAAMLGSN 60 L +R + G +++EVL+ + +I + + S E+N + +N Sbjct: 16 LSARRKKEQDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNEQNNVLTVIAN 73
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 404 bits (1039), Expect = e-130 Identities = 129/800 (16%), Positives = 249/800 (31%), Gaps = 85/800 (10%) Query: 49 YYLELVING--RDSGQVVPVNAADGHYL---LDAAALREAGVRLPGNPAGQVAVD----- 98 Y +++ +N + V + L A L G+ + D Sbjct: 78 YRVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVP 137 Query: 99 ---ALPEVRADYDSASQQLHLQVPPDWLPEQRFDDPGLVARA-PARSSLGALFNYDLYYS 154 + + A D Q+L+L +P ++ + G + L NY+ + Sbjct: 138 LTSMIHDATAQLDVGQQRLNLTIPQAFMSNR---ARGYIPPELWDPGINAGLLNYNFSGN 194 Query: 155 DPAD-GATPWLSALLEQRLFDGFGV--ISNTGVYTRYFGDADNLDSRYLRYDTYWLYNDE 211 + A L + G + + ++ D+ + ++ WL D Sbjct: 195 SVQNRIGGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDI 254 Query: 212 RNMHS-YQLGDYVNGALNWTTPVRMGGFRFARNFGVRPDLVTYPLLRFDGQAAVPSTVDL 270 + S LGD + + G + A + + PD G A + V + Sbjct: 255 IPLRSRLTLGDGYTQGDIFDG-INFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTI 313 Query: 271 FINGYKASSADLQPGPFAISNVPYINGAGEATVVTTDAQGRQVVTSLPFYVSNTLLARGL 330 NGY ++ + PGPF I+++ +G+ V +A G + ++P+ L G Sbjct: 314 KQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGH 373 Query: 331 SDFDLSVGRLRDDYGLRNFSYADNAASGIYRYGVSDRLTLSTHAEAASDLRLLGIGGDIA 390 + + ++ G R + +G+ T+ + A R G Sbjct: 374 TRYSITAGEYRSGNAQQ---EKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKN 430 Query: 391 VATFGTLSLAASGSDGQGDSGQQY---------------------LLGYSYYSRR-LGLS 428 + G LS+ + ++ Q+ L+GY Y + + Sbjct: 431 MGALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFA 490 Query: 429 LQHIERSAGYGDLGTLDGEYQLSRRTD------------QATASLTFDEQGTIGTGYFDI 476 R GY + TD Q T + T+ Sbjct: 491 DTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQ 550 Query: 477 RARDGS-RTRLANLSYSRPIGSRS-SFYLALNKDLDGDGYSALMQLVIPFDI-------- 526 S + + + +L K+ G ++ L + Sbjct: 551 TYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHWLRSDS 610 Query: 527 -----NGLLNIGVTRDSDRRYSERVIWSRSTPSQGGLGWNL------GHGGGASRYQQAD 575 + + ++ D + R + + L +++ G G + A Sbjct: 611 KSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYAT 670 Query: 576 LTWRMQNVQLQGGLYGETGNYTRWADLSGSLVWMDNAVFASNRINDAFVLVSTKGYPQVP 635 L +R G + +SG ++ N V +ND VLV G Sbjct: 671 LNYRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAK 730 Query: 636 IRYENQLMGSTDDNGHLLVPWVAAYYPAKFQIEPLDLPANVSAPEVEQRVAVRQGSGLLL 695 + ENQ TD G+ ++P+ Y + ++ L NV V +G+ + Sbjct: 731 V--ENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRA 788 Query: 696 DFPIRAVVAASINLVDERGEPLPLGSQAEETGSGQRASVGWDGQVYFEGLQSDNQLRVV- 754 +F R + + L +PLP G+ S V +GQVY G+ +++V Sbjct: 789 EFKARVGIKLLMTLTHN-NKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKW 847 Query: 755 -RPDGRACQARFRLDTRKPT 773 + C A ++L Sbjct: 848 GEEENAHCVANYQLPPESQQ 867
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 56.8 bits (137), Expect = 2e-10 Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 20/143 (13%) Query: 3 VGTAGHIDHGKTSLLRAL---TGI--------EGDRRP----AERQRGITIDLGYLYADL 47 +G H+D GKT+L +L +G +G R ERQRGITI G Sbjct: 6 IGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQW 65 Query: 48 GDGSPTGFIDVPGHERFVHNMLAGASGIDCVLLVVAADDGLMPQTREHLAIVELLGIRRA 107 + + ID PGH F+ + S +D +L+++A DG+ QTR + +GI Sbjct: 66 -ENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT- 123 Query: 108 LVALTKIDR--VEPQRV-QQVRT 127 + + KID+ ++ V Q ++ Sbjct: 124 IFFINKIDQNGIDLSTVYQDIKE 146
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.0 bits (187), Expect = 4e-18 Identities = 42/156 (26%), Positives = 74/156 (47%), Gaps = 6/156 (3%) Query: 2 RILVIEDDTKTGEYLKKGLGESGYAVDWSQHGADGLYLALENRYDLVVLDVMLPGLDGWQ 61 ILV +DD L + L +GY V + + A DLVV DV++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 IMEVLRK-KHDVPVLFLTARDQLQDRIRGLELGADDYLVKPFSFTELLLRIRTLLRRGVV 120 ++ ++K + D+PVL ++A++ I+ E GA DYL KPF TEL+ I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 REAEQVQLADLQLDVLR-----RKVSRQGQVIALTN 151 R ++ + + ++ +++ R + T+ Sbjct: 125 RPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTD 160
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 32.9 bits (75), Expect = 0.002 Identities = 70/330 (21%), Positives = 115/330 (34%), Gaps = 37/330 (11%) Query: 44 GGLMASYYFGLVCGGKFGHKLIASFGHIRSYVACAGI--ATVTVLLHALVDQLEVWLLLR 101 G L+A Y L FG R V + A V + A L V + R Sbjct: 46 GILLALYALMQFACAPVLGALSDRFG--RRPVLLVSLAGAAVDYAIMATAPFLWVLYIGR 103 Query: 102 F---ITGAVMMNQYMVIESWLNEQAESHQRGKVFAGYMVA-VDLGLVLGQ---GLLA-LS 153 ITGA V +++ + + +R + F G+M A G+V G GL+ S Sbjct: 104 IVAGITGATGA----VAGAYIADITDGDERARHF-GFMSACFGFGMVAGPVLGGLMGGFS 158 Query: 154 PTLDY---KPLLLVAICFASCLIPLAMTRRVHPAKLVAAPLEVRFFWQR----VPQALGT 206 P + L + L+P + P + A F W R V + Sbjct: 159 PHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAV 218 Query: 207 IFIAGLMVGAFYGLAPVY-ANRNGLDASQSSF-FVGMCIVAGFCAQWPLG----WLSDRL 260 FI L+ L ++ +R DA+ I+ G L +R Sbjct: 219 FFIMQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERR 278 Query: 261 DRSWLIRGNAVLLCLASIPMWGLVTLPYWLLLANGFVTGMLLFTLYPLAVALANDHVEQP 320 + + L + G + P +LLA+G G+ + P A+ + V++ Sbjct: 279 ALMLGMIADGTGYILLAFATRGWMAFPIMVLLASG---GIGM----PALQAMLSRQVDEE 331 Query: 321 RRVALSAMLLTTYGVGACIGPLVAGALMRH 350 R+ L L + + +GPL+ A+ Sbjct: 332 RQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 6e-15 Identities = 32/179 (17%), Positives = 57/179 (31%), Gaps = 10/179 (5%) Query: 1 MSSPRAEQKQQTRHALMSAARHLMESGRGFGSLSLREVTRAAGIVPAGFYRHFSDMDQLG 60 M+ ++ Q+TR ++ A L +G S SL E+ +AAG+ Y HF D L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQ-QGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLF 59 Query: 61 LALVAEVDETFRATLR--AVRRNEFELGGLIDASVRIF-LDAVGANRSQF---LFLAREQ 114 + + + L L + + + R +F E Sbjct: 60 SEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEF 119 Query: 115 YGGSLPIRQAIASLRQRITDDLAADLALLNKMPHLDGAALDVFADLVVKTVFATLPELI 173 G ++QA +L D + L D+ + + L+ Sbjct: 120 VGEMAVVQQAQRNLCLESYDRIE---QTLKHCIEAKMLPADLMTRRAAIIMRGYISGLM 175
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 46.4 bits (110), Expect = 1e-07 Identities = 33/187 (17%), Positives = 75/187 (40%), Gaps = 5/187 (2%) Query: 16 NRTHWLILGWGCFIMLFDGYDMVIYGSVVPRLMQEWQLSPVQAGTLGSCALFGMLFGGTL 75 N H IL W C + F + ++ +P + ++ P + + + G + Sbjct: 9 NLRHNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAV 68 Query: 76 LAPLADRFGRRRLV---IATTLLASLAAFLTGHARDPLELGAGRFFTGLALGALVPSAIN 132 L+D+ G +RL+ I S+ F+ GH+ L L RF G A + Sbjct: 69 YGKLSDQLGIKRLLLFGIIINCFGSVIGFV-GHSFFSL-LIMARFIQGAGAAAFPALVMV 126 Query: 133 LISEFAPAGRRSTLVTVMSAFYSVGAVLSALLAIAMIPAWGWQSVFYVAVLPVLAVPLML 192 +++ + P R ++ + ++G + + + W + + ++ ++ VP ++ Sbjct: 127 VVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLM 186 Query: 193 RWLPESA 199 + L + Sbjct: 187 KLLKKEV 193 Score = 32.2 bits (73), Expect = 0.005 Identities = 28/152 (18%), Positives = 54/152 (35%), Gaps = 13/152 (8%) Query: 258 VAFAMCMLMSYG------LNTWLPKLMAGGGYALGSSLAFLVTLNVGATLGALFGGWLAD 311 + +C+L + LN LP + S+ + ++G G L+D Sbjct: 15 ILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSD 74 Query: 312 RLGAGRTLVLFFAL--AAASLAALGLGPGPWLLNGLLVVA--GATTIGTLAVIHAYAAQF 367 +LG R L+ + + + +G L+ + A + V+ A++ Sbjct: 75 QLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVV---VARY 131 Query: 368 YPAWVRSTGVGWAAGVGRLGAIAGPMLGGSLL 399 P R G + +G GP +GG + Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIA 163
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 50.2 bits (120), Expect = 9e-09 Identities = 40/147 (27%), Positives = 57/147 (38%), Gaps = 8/147 (5%) Query: 55 AEIGLLLSAGLFGMAAGSLFIAPWADRWGRRPLILACLALSGLGMLASALSQAAWQLALL 114 A G+LL+ A + + +DR+GRRP++L LA + + A + W L + Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIG 102 Query: 115 R---GLTGLGIGGILASSNVIASEYASRRWRGLAVSLQSTGYALGATLGGLLAVWLIGAW 171 R G+TG A I R G + G G LGGL+ G + Sbjct: 103 RIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLM-----GGF 157 Query: 172 GWRSVFVFGAGLTLAVIPLVCLCLPES 198 + F A L C LPES Sbjct: 158 SPHAPFFAAAALNGLNFLTGCFLLPES 184 Score = 36.7 bits (85), Expect = 1e-04 Identities = 34/146 (23%), Positives = 59/146 (40%), Gaps = 7/146 (4%) Query: 51 NLGGAEIGLLLSA-GLFGMAAGSLFIAPWADRWGRRPLILACLALSGLGMLASALSQAAW 109 + IG+ L+A G+ A ++ P A R G R ++ + G G + A + W Sbjct: 242 HWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFATRGW 301 Query: 110 QLALLRGLTGLGIGGILASSNVIASEYASRRW---RGLAVSLQSTGYALGATLGGLLAVW 166 + L G G+ A +++ + R +G +L S +G L + Sbjct: 302 MAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361 Query: 167 LIGAW-GWRSVFVFGAGLTLAVIPLV 191 I W GW ++ GA L L +P + Sbjct: 362 SITTWNGW--AWIAGAALYLLCLPAL 385 Score = 34.4 bits (79), Expect = 8e-04 Identities = 41/189 (21%), Positives = 66/189 (34%), Gaps = 5/189 (2%) Query: 253 RTTLLLWALFFLVMFGFYFIMSWTPKLLVAAGLSTAQGITGGTLLSIGGI---FGAALLG 309 R +++ + L G IM P LL S G LL++ + A +LG Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 310 GLAARFRLERVLALFMLLTAALLALFSLSAGLPGAALPLGLLIGLCANACVAGLYALAPS 369 L+ RF VL + + A A+ + + L L +G ++ A A A Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL--WVLYIGRIVAGITGATGAVAGAYIAD 122 Query: 370 LYDASVRATGVGWGIGVGRGGAILSPLVAGLLLDDGWQPLSLYGAFAAVFVAAAAVLPLL 429 + D RA G+ G + P++ GL+ A L Sbjct: 123 ITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLP 182 Query: 430 GARRRERSP 438 + + ER P Sbjct: 183 ESHKGERRP 191
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.5 bits (126), Expect = 6e-09 Identities = 31/143 (21%), Positives = 52/143 (36%), Gaps = 8/143 (5%) Query: 748 SALEVLLVEDVALNREVAQGLLERDGHRVMLAEDAGPALALCRQRRFDLILLDMHLPGMA 807 + +L+ +D A R V L R G+ V + +A DL++ D+ +P Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 808 GLELCAGIRRQLDGLNRATPIFAFTASIQPDMVRRYFAAGMQGVLGKPLRMDEL----RR 863 +L I++ L P+ +A + G L KP + EL R Sbjct: 62 AFDLLPRIKKARPDL----PVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 864 ALGEVGTSVPALAVDAALDRQML 886 AL E L D+ ++ Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPLV 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 92.2 bits (229), Expect = 1e-23 Identities = 34/136 (25%), Positives = 60/136 (44%), Gaps = 6/136 (4%) Query: 5 PRVLVVDDDPVIRELLQAYLGEEGYDVLCAGNAEQAEACLAECAHLGQPVELVLLDIRLP 64 +LV DDD IR +L L GYDV NA +A +LV+ D+ +P Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAA-----GDGDLVVTDVVMP 58 Query: 65 GKDGLTLTRELR-VRSEVGIILITGRNDEIDRIVGLECGADDYVIKPLNPRELVSRAKNL 123 ++ L ++ R ++ +++++ +N + I E GA DY+ KP + EL+ Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 124 IRRVRHAQASAGPARQ 139 + + + Q Sbjct: 119 LAEPKRRPSKLEDDSQ 134
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 74.7 bits (183), Expect = 1e-18 Identities = 34/184 (18%), Positives = 65/184 (35%), Gaps = 4/184 (2%) Query: 6 RFSRLEPEQRKALLIEATLACLKRHGFQGASVRKICAEAGVSVGLINHHYDGKDALVAEA 65 R ++ E ++ + +++ L + G S+ +I AGV+ G I H+ K L +E Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 66 YLAVTGRVMRLLRGAIDTAPGGARPRLSAFFEASFSAELLDPQ---LLDAWLAFWGAVGS 122 + + L PG L + + + + L++ VG Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 123 IEAIGRVHDHSYGEYRALLVGVLRQLAEEGGW-ADFDAELAAISLSALLDGLWLESGLNP 181 + + + + E + L+ E AD AAI + + GL P Sbjct: 123 MAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAP 182 Query: 182 ATFT 185 +F Sbjct: 183 QSFD 186
>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein signature. Length = 166 Score = 28.2 bits (63), Expect = 0.044 Identities = 14/57 (24%), Positives = 26/57 (45%), Gaps = 7/57 (12%) Query: 346 GCFDILHAGHVTYLEQARAQGDRLIVGVNDDASVTRLKGVGRPINSVDRRMAVLAGL 402 G FD + GH+ +E+ D++ V V + + +P+ SV R+ +A Sbjct: 7 GSFDPITFGHLDIIERGCRLFDQVYVAVLRNPN-------KQPMFSVQERLEQIAKA 56
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 31.3 bits (71), Expect = 0.013 Identities = 12/50 (24%), Positives = 23/50 (46%) Query: 144 ITFNVTMVTGAATDAIKVVIREGLTVVFLFLYLLWMNWKLTLVMLAILPV 193 ++ T + + + E + +VFL +YL N + TL+ +PV Sbjct: 325 YPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPV 374
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 60.0 bits (145), Expect = 2e-13 Identities = 30/148 (20%), Positives = 57/148 (38%), Gaps = 8/148 (5%) Query: 1 MKTRDRILECSLLLFNEQGEPNVSTLEIANELGISPGNLYYHFHGKEPLVMALFERFQAE 60 +TR IL+ +L LF++QG + S EIA G++ G +Y+HF K L ++E ++ Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 LAPLL-----DPPEEVRLGAEDYWLFLHLIVERLAHYRFLFQDL---SNLTGRLPRLARG 112 + L P + + + + R L + + G + + + Sbjct: 70 IGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQA 129 Query: 113 IRTWLGALKRTLATLLARLKADRQLRSD 140 R + L + L +D Sbjct: 130 QRNLCLESYDRIEQTLKHCIEAKMLPAD 157
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 47.0 bits (111), Expect = 6e-08 Identities = 34/200 (17%), Positives = 64/200 (32%), Gaps = 6/200 (3%) Query: 110 VPSRNEVKELHSKVDTLTKQIEKLTGVSVKPAAKAAAKPAAKPAA---KPAAKTAAAKPA 166 + + N ++ V + ++I ++ V P A A + A K +KT Sbjct: 997 ITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQ 1056 Query: 167 AKPAAKAAAKPAAKPAAKKTAAKTAAAKPA--AKPAAKPTAKAAAKPATKPAA-KAAAKP 223 A + AK A A T + A + + AT KA + Sbjct: 1057 DATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEEKAKVET 1116 Query: 224 AAKPAAAKPAAKPAAKPAAATAAKPAAKPAAKPAAKKPAAKKPAAKPAAAKPAAPAASSS 283 K ++ + K + +P A+PA + + + A PA +S Sbjct: 1117 EKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETS 1176 Query: 284 APAAPAATPAASAPAANAPA 303 + T + + N+ Sbjct: 1177 SNVEQPVTESTTVNTGNSVV 1196 Score = 42.7 bits (100), Expect = 1e-06 Identities = 27/175 (15%), Positives = 42/175 (24%), Gaps = 6/175 (3%) Query: 140 PAAKAAAKPAAKPAAKPAAKTAAAKPAAKPAAKAAAK----PAAKPAAKKTAAKTAAAKP 195 P + + A P+ + A+ P PA + T Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 196 AAKPAAKPTAKAAAKPA-TKPAAKAAAKPAAKPAAAKPAAKPAAKPAAATA-AKPAAKPA 253 +K +K K T + AK A A A+ + T + Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKE 1102 Query: 254 AKPAAKKPAAKKPAAKPAAAKPAAPAASSSAPAAPAATPAASAPAANAPATPSSQ 308 K+ AK K S + P A N P + Sbjct: 1103 TATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKE 1157
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 36.3 bits (84), Expect = 2e-04 Identities = 17/33 (51%), Positives = 21/33 (63%) Query: 341 LAGVTLHAARALGLEASHGSLEVGKLADFVAWD 373 +A T++ A A GL GSLEVGK AD V W+ Sbjct: 406 IAKYTINPAIAHGLSHEIGSLEVGKRADLVLWN 438
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 31.2 bits (70), Expect = 0.012 Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 12/109 (11%) Query: 540 RTDKRAQRQAAAALRQQLAPHKREADKLERELGGLHEKLAA-------IEARLG----DS 588 R D A R+A L + + + E L L A +EA + Sbjct: 315 RRDLDASREAKKQLEAEHQKLEEQNKISEASRQSLRRDLDASREAKKQLEAEHQKLEEQN 374 Query: 589 ALYDVSRKDELRELLSEQSSLKVREGELEERWLEALETLEALQKELEAS 637 + + SR+ R+L + + + K E LEE + L LE L KELE S Sbjct: 375 KISEASRQSLRRDLDASREAKKQVEKALEEANSK-LAALEKLNKELEES 422
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 61.2 bits (148), Expect = 3e-12 Identities = 43/220 (19%), Positives = 66/220 (30%), Gaps = 7/220 (3%) Query: 134 KAKPATKPAAKAAAKPAVKTVAAKPAAKPAAKPAAKPA-AKPAAKTAAAKPAAKPTAKPA 192 T P A P+V + + A+ P PA A P+ T +K +K Sbjct: 993 DTTNITTPNNIQADVPSVPSNNEE-IARVDEAPVPPPAPATPSETTETVAENSKQESKTV 1051 Query: 193 AKPAAKPAAKTAAAKPAAKPAAKPVAKPAAKPAAKTAAAKPAAKPAAKPVAKPTAKPAAK 252 K TA + AK A V A + A + K K TA + Sbjct: 1052 EKNEQDATETTAQNREVAKEAKSNV--KANTQTNEVAQSGSETKETQTTETKETATVEKE 1109 Query: 253 TAAAKPAAKPAAKPAAKPAAKPVAKPAAAKPAAKPAAKPAAKPAAKPAAKPVAAKPAAAK 312 A K P P +P A+PA + K ++ Sbjct: 1110 EKAKVETEKTQEVPKVTSQVSP---KQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTA 1166 Query: 313 PATAPAAKPAATPSAPAAASSAASATPAAGSNGAAPTSAS 352 PA + ++ P S+ + + N T A+ Sbjct: 1167 DTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPAT 1206 Score = 45.1 bits (106), Expect = 4e-07 Identities = 40/246 (16%), Positives = 80/246 (32%), Gaps = 19/246 (7%) Query: 45 EKQRGKAQEKLHKARTKLQDAAKAGKTKAQAK--ARETISDLEEALDTLKARQADTRTYI 102 E A+ +++T ++ A +T AQ + A+E S+++ T + Q Sbjct: 1035 ETTETVAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQ------- 1087 Query: 103 VGLKRDVQESLKLAQGVGKVKEAAGKA-LESRKAKPATKPAAKAAAKPAVKTVAAKPAAK 161 + +E+ E KA +E+ K + K ++ + K ++ +P A+ Sbjct: 1088 --SGSETKETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQE-QSETVQPQAE 1144 Query: 162 PAAKPA----AKPAAKPAAKTAAAKPAAKPTAKPAAKPAAKPAAKTAAAKPAAKPAAKPV 217 PA + K TA + AK T+ +P + P + Sbjct: 1145 PARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP--ENT 1202 Query: 218 AKPAAKPAAKTAAAKPAAKPAAKPVAKPTAKPAAKTAAAKPAAKPAAKPAAKPAAKPVAK 277 +P + ++ + V T ++ + A V Sbjct: 1203 TPATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLS 1262 Query: 278 PAAAKP 283 A AK Sbjct: 1263 DARAKA 1268 Score = 36.2 bits (83), Expect = 2e-04 Identities = 17/119 (14%), Positives = 28/119 (23%), Gaps = 1/119 (0%) Query: 233 PAAKPAAKPVAKPTAKPAAKTAAAKPAAKPAAKPAAKPAAKPVAKPAAAKPAAKPAAKPA 292 P + + V A P+ + A+ PV PA A P+ Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAE 1042 Query: 293 AKPAAKPAAKPVAAKPAAAKPATAPAAKPAATPSAPAAASSAASATPAAGSNGAAPTSA 351 + AK A + A + A + + T Sbjct: 1043 NSKQESKTVEKNEQDATETTAQNREVAK-EAKSNVKANTQTNEVAQSGSETKETQTTET 1100
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 95.8 bits (238), Expect = 2e-26 Identities = 61/202 (30%), Positives = 97/202 (48%), Gaps = 16/202 (7%) Query: 22 KDELAYAVGARLGMRLQQEMPGLELSELLLGLRQAYRGEALEIPPERIEQLLLQHE---- 77 KD+L+Y++GA LG + + + L G++ G L + E+++ +L + + Sbjct: 31 KDKLSYSIGADLGKNFKNQGIDINPDVLAKGMQDGMSGAQLILTEEQMKDVLSKFQKDLM 90 Query: 78 -------NATTETPRTTPAEARFLANEKARFGVRELTGGVLVSELRRGQGNGIGAATQVH 130 N E + +A FL+ K++ G+ L G+ + G G G + V Sbjct: 91 AKRSAEFNKKAEENKAK-GDA-FLSANKSKPGIVVLPSGLQYKIIDAGTGAKPGKSDTVT 148 Query: 131 VRYRGLLADGQVFDQSESA---EWFALDSVIEGWRTALRAMPVGARWRVVIPSAQAYGHE 187 V Y G L DG VFD +E A F + VI GW AL+ MP G+ W V +P+ AYG Sbjct: 149 VEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGWTEALQLMPAGSTWEVFVPADLAYGPR 208 Query: 188 GAGDLIPPDAPLVFEIDLLGFR 209 G I P+ L+F+I L+ + Sbjct: 209 SVGGPIGPNETLIFKIHLISVK 230
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 4e-19 Identities = 31/136 (22%), Positives = 57/136 (41%), Gaps = 5/136 (3%) Query: 3 VLIVDDEPLARERLARLVGQLDGYRVLEPSASNGEEALTLIDSLKPDIVLLDIRMPGLDG 62 +L+ DD+ R L + + + GY V SN I + D+V+ D+ MP + Sbjct: 6 ILVADDDAAIRTVLNQALSRA-GYDVR--ITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 63 LQVAARLCEREAPPAVIFCTAHDEF--ALEAFQVSAVGYLVKPVRSEDLAEALKKASRPN 120 + R+ + V+ +A + F A++A + A YL KP +L + +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 121 RVQLAALTKPPASGGS 136 + + + L G Sbjct: 123 KRRPSKLEDDSQDGMP 138
>PF06580#Sensor histidine kinase Length = 349 Score = 182 bits (463), Expect = 1e-56 Identities = 76/308 (24%), Positives = 137/308 (44%), Gaps = 23/308 (7%) Query: 64 LFVQWIVLLSAALFCRLRPLLARLPVALAGSACCLLVVALT------LGCTAVAEHYQLG 117 +F I L+ L R + R +L V + A ++L Sbjct: 43 IFNIAISLMGLVLTHAYRSFIKRQGWLKLNMGQIILRVLPACVVIGMVWFVANTSIWRLL 102 Query: 118 GELTRAGE-------VNLYLRHALIALIMSALVLRYFYLQS-------QWRRQQQAELQA 163 + +++ ++ + S L + + ++ QW+ A+ +A Sbjct: 103 AFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQAEIDQWKMASMAQ-EA 161 Query: 164 RLESLQARIRPHFLFNSLNSIASLIELDPLKAEHAVLDLSDLFRASLAK-PGTLVSWEEE 222 +L +L+A+I PHF+FN+LN+I +LI DP KA + LS+L R SL VS +E Sbjct: 162 QLMALKAQINPHFMFNALNNIRALILEDPTKAREMLTSLSELMRYSLRYSNARQVSLADE 221 Query: 223 LALARRYLSIEQYRLGDRLQLDWQVHGVPANLPIPQLTLQPLLENALIYGIQPRVEGGLV 282 L + YL + + DRLQ + Q++ ++ +P + +Q L+EN + +GI +GG + Sbjct: 222 LTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIAQLPQGGKI 281 Query: 283 QVEAVYREGVFQLCVSNPYDEALESPPSKGTRQALHNIDARLGALFGPKASLSVERRDGR 342 ++ G L V N AL++ + T L N+ RL L+G +A + + + G+ Sbjct: 282 LLKGTKDNGTVTLEVENTGSLALKNTK-ESTGTGLQNVRERLQMLYGTEAQIKLSEKQGK 340 Query: 343 HYTCLRYP 350 + P Sbjct: 341 VNAMVLIP 348
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 111 bits (280), Expect = 4e-36 Identities = 41/87 (47%), Positives = 58/87 (66%) Query: 3 KPELAAAIAEKADLTKEQANRVLNALLDEITGALNRKDSVTLVGFGTFLQRHRGARTGKN 62 K +L A +AE +LTK+ + ++A+ ++ L + + V L+GFG F R R AR G+N Sbjct: 4 KQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGRN 63 Query: 63 PQTGQPVKIKASNTVAFKPGKALRDAV 89 PQTG+ +KIKAS AFK GKAL+DAV Sbjct: 64 PQTGEEIKIKASKVPAFKAGKALKDAV 90
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 33.6 bits (77), Expect = 0.002 Identities = 35/155 (22%), Positives = 52/155 (33%), Gaps = 16/155 (10%) Query: 5 LLPVLLFAALALAVLGAAKRFLMWRRGRPAKVDWIGGL----MQMPRRYLVDLHHVVERD 60 LL L AA+ A++ A + GR + G+ + Y+ D+ ER Sbjct: 76 LLVSLAGAAVDYAIMATAPFLWVLYIGR-----IVAGITGATGAVAGAYIADITDGDERA 130 Query: 61 RYMSRTHVATAGGFVLAALLAILVHGFGLHGRILGFALLAATALMFVGALF--VARRRLD 118 R+ G V +L L+ GF H A L + L + Sbjct: 131 RHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKGERR 190 Query: 119 PPSRLSKGP-----WMRLPKSLLAFAASFFLATLP 148 P R + P W R + A A FF+ L Sbjct: 191 PLRREALNPLASFRWARGMTVVAALMAVFFIMQLV 225
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.1 bits (117), Expect = 1e-08 Identities = 23/129 (17%), Positives = 41/129 (31%), Gaps = 9/129 (6%) Query: 75 VGGKIVERLVDVGDHVAAGQVLARLDP-------QDQRSNVENAQAAVAAQQAQSKLADL 127 + E +V G+ V G VL +L +S++ A+ Q S+ +L Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 128 NYQRQKALLPKGYTSQSEYDQALASVRSAQSSLKAAQAQLANARDLLSYTELRASDAGVI 187 N + L + Y ++ L + Q Q L+ + RA V+ Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKE--LNLDKKRAERLTVL 220 Query: 188 TARQAEVGQ 196 Sbjct: 221 ARINRYENL 229 Score = 42.9 bits (101), Expect = 2e-06 Identities = 33/216 (15%), Positives = 71/216 (32%), Gaps = 26/216 (12%) Query: 58 SITGDIQARVQADQSFRVGGKIVERLVDVGDHVAAGQVLARLDPQDQRSNVENAQAAVAA 117 ++ I + + L+ A A L+ +++ N + Sbjct: 218 TVLARINRYENLSRVEKSRLDDFSSLLHKQ----AIAKHAVLEQENKYVEAVNELRVYKS 273 Query: 118 QQAQSKLADLNYQRQKALLPKGYTSQSEYDQALASVRSAQSSLKAAQAQLANARDLLSYT 177 Q Q + L+ + + L+ + + ++ L +R ++ +LA + + Sbjct: 274 QLEQIESEILSAKEEYQLVTQLFKNE-----ILDKLRQTTDNIGLLTLELAKNEERQQAS 328 Query: 178 ELRASDAGVITARQA-EVGQVVQATVPIFTLARDGERDAVFNVYESLFSHDVDGQRITVS 236 +RA + + + G VV + + + D V + + D+ I V Sbjct: 329 VIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE---DDTLEVTALVQNKDIG--FINVG 383 Query: 237 LLGKPEVTA---------SGKVREITP--TVDERSG 261 +V A GKV+ I D+R G Sbjct: 384 QNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLG 419
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 39.8 bits (93), Expect = 1e-05 Identities = 16/103 (15%), Positives = 32/103 (31%), Gaps = 3/103 (2%) Query: 63 TNGRIASRLFDVGDFVGKGALLATLDPTDQQNQLRASQGDLASAEAQLIDAQANARRQEE 122 N + + G+ V KG +L L + +Q L A + Q +R E Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 123 --LFARSVTAQARLDDARTR-LKTSQASFDQAKAAVQQARDQL 162 L + + + + + + + Q + Q Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQK 205 Score = 39.0 bits (91), Expect = 2e-05 Identities = 23/182 (12%), Positives = 59/182 (32%), Gaps = 31/182 (17%) Query: 51 IQARYESVLGFRTNGRIASRLFDVGDFVGKGALLATLDPTDQQNQLRASQGDLASAEAQL 110 I ++ S L + K A+L +Q+N+ + +L ++QL Sbjct: 223 INRYENLSRVEKSRLDDFSSLLHKQ-AIAKHAVL------EQENKYVEAVNELRVYKSQL 275 Query: 111 IDAQANARRQEELFARSVTAQARLDDARTRLKTSQASFDQAKAAVQQARDQLSYTRLVTD 170 ++ +E + Q ++ +L+ + + + + ++ + + Sbjct: 276 EQIESEILSAKE--EYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAP 333 Query: 171 FDGVITTW--HAEAGQVVSAGQAVVTLARPEVREAVFDLPTEVAESLPADARFLVSAQLD 228 + H E G VV+ + ++ + P D V+A + Sbjct: 334 VSVKVQQLKVHTE-GGVVTTAETLMVIV-------------------PEDDTLEVTALVQ 373 Query: 229 PQ 230 + Sbjct: 374 NK 375
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 490 bits (1263), Expect = e-159 Identities = 240/1052 (22%), Positives = 444/1052 (42%), Gaps = 69/1052 (6%) Query: 7 LSDWALRHQSLVWYLMAVSLVMGVFSYLNLGREEDPSFAIKTMVIQTRWPGATVDDTLEQ 66 ++++ +R W L + ++ G + L L + P+ A + + +PGA + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 67 VTDRIEKKLEELDSLDYVKSYT-RPGESTVFVYLKDTTKAGDIPDIWYQVRKKISDIQGE 125 VT IE+ + +D+L Y+ S + G T+ + + T D QV+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGT---DPDIAQVQVQNKLQLATPL 117 Query: 126 FPQGIQGPG-FNDEFGDVFGSVYAFTADGLDFRQ--LRDYVEKVRLD-IRSVKDLGKVQM 181 PQ +Q G ++ + V F +D Q + DYV D + + +G VQ+ Sbjct: 118 LPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQL 177 Query: 182 IGAQNEV-IYLNFSTRKLAALGLDQRQVVQSLQAQNAVTPSGVVEAGPE------RISVR 234 GAQ + I+L+ L L V+ L+ QN +G + P S+ Sbjct: 178 FGAQYAMRIWLDAD--LLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 235 TSGNFRSEKDLQAVNLRVNDRFY--RLSDLASISRDFVDPPTSLFRYKGEPAIGLAVAMK 292 F++ ++ V LRVN RL D+A + + + R G+PA GL + + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARV-ELGGENYNVIARINGKPAAGLGIKLA 294 Query: 293 EGGNILEFGEALNARMQEITGELPVGVGVHQVSNQAQVVKKAVGGFTRALFEAVVIVLIV 352 G N L+ +A+ A++ E+ P G+ V + V+ ++ + LFEA+++V +V Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 353 SFVSLG-LRAGLVVACSIPLVLAMVFVFMEYTDITMQRVSLGALIIALGLLVDDAMITVE 411 ++ L +RA L+ ++P+VL F + ++ +++ +++A+GLLVDDA++ VE Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 412 MMITRLELGDSLHDSATY-AYTSTAFPMLTGTLVTVAGFVPIGLNASSAGEYTFTLFAVI 470 + + AT + + ++ +V A F+P+ S G I Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 471 AVALLLSWIVAVLFAPVIAVHILPKTLKHKSEQKKG---RIAERFDSLLHLA-------M 520 A+ LS +VA++ P + +L E K G FD ++ + Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKIL 534 Query: 521 RRRWTTIFLTALLFGVSLFLMKFVQHQFFPSSDRPELLVDLNLPQNSSIHETRAVMDR-L 579 + + AL+ + L + F P D+ L + LP ++ T+ V+D+ Sbjct: 535 GSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVT 594 Query: 580 EATLKDDEDID-HWSAYVGEGAIRFYLPLDQQLQNNFYGQLVIVTKDLEAR---ERVAAR 635 + LK+++ G Q QN + K E R E A Sbjct: 595 DYYLKNEKANVESVFTVNGFS-------FSGQAQNAGMAF--VSLKPWEERNGDENSAEA 645 Query: 636 LRDRLRKDYVGI-STYVQPLEMGPPV--------GRPIQYRVSGPQIDKVREYAMGLAGV 686 + R + + I +V P M P + +G D + + L G+ Sbjct: 646 VIHRAKMELGKIRDGFVIPFNM-PAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGM 704 Query: 687 LDGNP-NIGDIVYDWNEPGKMLKIDIAQDKARQLGLSSEDVAQIMNSVVTGSAVTQVRDD 745 +P ++ + + E K+++ Q+KA+ LG+S D+ Q +++ + G+ V D Sbjct: 705 AAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR 764 Query: 746 IYLVNVIGRAEDSERGSLETLESLQIVTPSGTSIPLKAFAKVSYELEQPLVWRRDRKPTI 805 + + +A+ R E ++ L + + +G +P AF + P + R + P++ Sbjct: 765 GRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSM 824 Query: 806 TVKASLRGEIQPTDLVARLAPEVKRFADGLPANYRIEVGGTVEESGKAEGPIAKVVPLML 865 + +GE P ++ A LPA + G + + +V + Sbjct: 825 EI----QGEAAPGTSSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISF 880 Query: 866 FLMATFLMIQLQSVQKLFLVASVAPLGLIGVVAALLPTGTPMGFVAILGILALIGIIIRN 925 ++ L +S V V PLG++GV+ A ++G+L IG+ +N Sbjct: 881 VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940 Query: 926 SVILVTQI-DAFEKDGKTPWEAVLEATHHRTRPILLTAAAASLGMIPIA------REVFW 978 ++++V D EK+GK EA L A R RPIL+T+ A LG++P+A Sbjct: 941 AILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQN 1000 Query: 979 GPMAYAMIGGIVAATLLTLIFLPALYVAWYRI 1010 + ++GG+V+ATLL + F+P +V R Sbjct: 1001 -AVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031 Score = 79.1 bits (195), Expect = 5e-17 Identities = 79/517 (15%), Positives = 172/517 (33%), Gaps = 35/517 (6%) Query: 518 LAMRRRWTTIFLTALLFGVSLFLMKFVQHQFFPSSDRPELLVDLNLPQNSSIHETRAVMD 577 +RR L +L + + +P+ P + V N P + V Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 578 RLEATLKDDEDIDHWSAYVGEGAIRFYLPLDQQLQNNFYGQLVIVTKDLEARERVAARLR 637 +E + +++ + S+ + A + L Q + V V + L Sbjct: 64 VIEQNMNGIDNLMYMSS-TSDSAGSVTITLTFQSGTDPDIAQVQVQ---NKLQLATPLLP 119 Query: 638 DRLRKDYVGISTYVQPLEMG----PPVGRPIQYRVSGPQIDKVREYAMGLAGVLDGNPNI 693 +++ + + M Q +S V++ L GV D Sbjct: 120 QEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 694 GDIVYDWNEPGKMLKIDIAQDKARQLGLSSEDVAQIMNS----VVTGSAVTQVRDDIYLV 749 ++I + D + L+ DV + + G + Sbjct: 180 AQ---------YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQL 230 Query: 750 NVIGRAEDSERGSLETLESLQI-VTPSGTSIPLKAFAKVSYELE-QPLVWRRDRKPTITV 807 N A+ + E + + V G+ + LK A+V E ++ R + KP + Sbjct: 231 NASIIAQT-RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGL 289 Query: 808 KASLRGEIQPTDLVARLAPEVKRFADGLPANYRIEVGGTVEESGKAEGPIAKVVPLML-- 865 L D + ++ P ++ + + + I +VV + Sbjct: 290 GIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLY--PYDTTPFVQLSIHEVVKTLFEA 347 Query: 866 -FLMATFLMIQLQSVQKLFLVASVAPLGLIGVVAALLPTGTPMGFVAILGILALIGIIIR 924 L+ + + LQ+++ + P+ L+G A L G + + + G++ IG+++ Sbjct: 348 IMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVD 407 Query: 925 NSVILVTQI-DAFEKDGKTPWEAVLEATHHRTRPILLTAAAASLGMIPIA-----REVFW 978 +++++V + +D P EA ++ ++ A S IP+A + Sbjct: 408 DAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIY 467 Query: 979 GPMAYAMIGGIVAATLLTLIFLPALYVAWYRIPEPGR 1015 + ++ + + L+ LI PAL + Sbjct: 468 RQFSITIVSAMALSVLVALILTPALCATLLKPVSAEH 504
>PHAGEIV#Gene IV protein signature. Length = 426 Score = 30.3 bits (68), Expect = 0.009 Identities = 15/76 (19%), Positives = 29/76 (38%), Gaps = 3/76 (3%) Query: 105 TRCRVLEVTPLARELIKSFCELPVDYPEGDSAESRLVQVLLDQLRLLPEVAFSLPMPREP 164 R ++ + +KS + D + +V D L LP+ ++ +P + Sbjct: 138 NNVRAKDLIRVVELFVKSNTSKSSNVLSVDGSNLLVVSAPKDILDNLPQFLSTVDLPTDQ 197 Query: 165 RLLRLCQALIDEPTQS 180 L+ + LI E Q Sbjct: 198 ILI---EGLIFEVQQG 210
>PF09025#YopR Core Length = 143 Score = 29.6 bits (66), Expect = 0.016 Identities = 26/90 (28%), Positives = 33/90 (36%), Gaps = 10/90 (11%) Query: 134 LPFEQLL---RPAIELARDGFPVSPVIARLWQSGLDKFRAALPQRPELRAWFDEFLIDGR 190 L FEQ L PA G + RL Q + R EL+A L GR Sbjct: 30 LAFEQALGGEPPAAGRRLAGLENGALGERLLQRFAQPLQGLEADRLELKAMLRAELPLGR 89 Query: 191 APRA------GEVFRQPGQADTLDELARSQ 214 + G V PG + L +LAR + Sbjct: 90 QQQTFLLQLLGAVEHAPG-GEYLAQLARRE 118
>CHANNELTSX#Nucleoside-specific channel-forming protein Tsx signature. Length = 294 Score = 45.8 bits (108), Expect = 6e-08 Identities = 38/135 (28%), Positives = 58/135 (42%), Gaps = 9/135 (6%) Query: 14 LLAAGQAVAEDHDMTPTHETDSGPLL---WHNESLTYLYGKNFKINPSIQQTFTLEHAS- 69 LLAAG VA + P W ++S+ + + + P I+ LE+ + Sbjct: 5 LLAAGAVVALSTTFAAGAAENDKPQYLSDWWHQSVNVVGSYHTRFGPQIRNDTYLEYEAF 64 Query: 70 -GWTWGDLFIFFDQ-INYNGKEDAS---NGKNTYYGEITPRLSFGKLTGADLSFGPVKDV 124 W D + + D + + G A N + + EI PR S KLT DLSFGP K+ Sbjct: 65 AKKDWFDFYGYIDAPVFFGGNSTAKGIWNKGSPLFMEIEPRFSIDKLTNTDLSFGPFKEW 124 Query: 125 LLAGTYEFGEGDTEA 139 A Y + G ++ Sbjct: 125 YFANNYIYDMGRNDS 139
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 66.2 bits (161), Expect = 2e-15 Identities = 32/219 (14%), Positives = 68/219 (31%), Gaps = 30/219 (13%) Query: 15 KPAGRIRQKNEEAILAAAEEEFARHGFKGTSMNTIAQNVGLPKANLHYYFGNKLGLYTAV 74 + + Q+ + IL A F++ G TS+ IA+ G+ + ++++F +K L++ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 75 LSNILELWDSTFNTLGVD--DDPAEALARYIRAKMEFSRRYPLASRIFA----------- 121 DP L + +E + + Sbjct: 63 WELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGE 122 Query: 122 MEIISGGECLTAHFNQDYRSWFRGRAAVFEAWIAAGRMDP-VDPVHLIFLLWGSTQHYAD 180 M ++ + + + + I A + + ++ G Y Sbjct: 123 MAVVQQAQ---RNLCLESYDRI---EQTLKHCIEAKMLPADLMTRRAAIIMRG----YIS 172 Query: 181 FASQIGLVTGR-KRMSRQDFAAAADNLVRIILKGCGLTP 218 GL+ D A + V I+L+ L P Sbjct: 173 -----GLMENWLFAPQSFDLKKEARDYVAILLEMYLLCP 206
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 59.3 bits (143), Expect = 5e-13 Identities = 30/170 (17%), Positives = 63/170 (37%), Gaps = 11/170 (6%) Query: 7 TRDRIAQASLELFNAQGERSVTTNHIATHLGISPGNLYYHYPNKQAIIAELFAEYESHVE 66 TR I +L LF+ QG S + IA G++ G +Y+H+ +K + +E++ ES++ Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 67 SFLRLPEGRGLTVDDKTF--YLEALLAAMWRYRFLHRDLEHLLESD------PELAARYR 118 + + L +L + +E + + R Sbjct: 72 ELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQR 131 Query: 119 AFAQRCLVNAKAIYRGFTEAGILR-MNETQLEALTLNAWI--ILTSWVRF 165 + + EA +L T+ A+ + +I ++ +W+ Sbjct: 132 NLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFA 181
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.0 bits (65), Expect = 0.024 Identities = 14/73 (19%), Positives = 28/73 (38%), Gaps = 15/73 (20%) Query: 79 GLQRALLERGWASVALN-----WRGCSGEPNRLPRGYHSGVSDDLAEVVAHLRARRPQAP 133 + L ++GW V + W+ + P+ V+ D ++ +A Sbjct: 69 AVGGILQQQGWPVVGWSSLKYYWK------QKDPKD----VTQDTLAIIDKYQAEFGTQK 118 Query: 134 LYAVGYSLGGNVL 146 + +GYS G V+ Sbjct: 119 VILIGYSFGAEVI 131
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 32.4 bits (74), Expect = 0.004 Identities = 27/109 (24%), Positives = 45/109 (41%), Gaps = 16/109 (14%) Query: 228 PTISREQLQAFHKKAYAAGN--VVIALVGDLS--RQEAEAIAAEVSKALPQGPALVKTVQ 283 I R QL+A +A GN V+ ++ L RQ + E K L +G + +++ Sbjct: 368 QDIFRTQLRAL-LRASTYGNLKVMFPMIATLEELRQAKAIMQEEKDKLLSEGVDVSDSIE 426 Query: 284 P----ETPKPGLT------HIDFPSEQTH-LMLAQLGIDRQDPDYAALY 321 E P + +DF S T+ L+ + DR + + LY Sbjct: 427 VGIMVEIPSTAVAANLFAKEVDFFSIGTNDLIQYTMAADRMNERVSYLY 475
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 45.4 bits (107), Expect = 2e-07 Identities = 24/105 (22%), Positives = 33/105 (31%) Query: 42 VEPVSETAAAEQRAPADDVAQSLTEQPGRQQPSAAEPAEPAPVAEAPLASDEPASAEEHS 101 V V E A Q VA + E P QP EP P E + A Sbjct: 37 VHQVIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEK 96 Query: 102 PRPEAPVAQPEPILAAEPEPEPEPEPEPEPVAPLAAAPAVSEPAT 146 P+P+ +P+ + +P APA +T Sbjct: 97 PKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSST 141 Score = 32.6 bits (74), Expect = 0.003 Identities = 23/115 (20%), Positives = 33/115 (28%), Gaps = 12/115 (10%) Query: 27 PQAGEQPADQPADQPVEPVSETAAAEQRAPADDVAQSLTEQPGRQQPSAAEPAEPAPVAE 86 P E P P EPV E + P P ++ P E +P P + Sbjct: 57 PADLEPPQAV--QPPPEPVVEPEPEPEPIPE----------PPKEAPVVIEKPKPKPKPK 104 Query: 87 APLASDEPASAEEHSPRPEAPVAQPEPILAAEPEPEPEPEPEPEPVAPLAAAPAV 141 + P P + E A P +PV +A+ P Sbjct: 105 PKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRA 159
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 28.6 bits (64), Expect = 0.032 Identities = 10/41 (24%), Positives = 17/41 (41%) Query: 293 ADGAQSVILNQVTYGIAIRMAVLSMAMSGQNTQRQLEQEDA 333 A G Q + N G+A+ +++ M + E ED Sbjct: 40 ALGLQQIPSNMTLNGVALLLSMFVMWPIMHDAYVYFEDEDV 80
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 60.4 bits (146), Expect = 9e-13 Identities = 31/183 (16%), Positives = 58/183 (31%), Gaps = 14/183 (7%) Query: 117 APFQDNQVKKVAPPAT--------PKQARSEEAPKAAVTTTRQRQQKAPSKTQAQKAEQV 168 AP Q V VAP P + E P+ ++ + K + Sbjct: 45 APAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPK 104 Query: 169 AKPAPHFDSTQLSAEIASLEADLAKEQQAYAKRPRIHRLSAASTMRDKGAWYKEDWRKKI 228 KP Q ++ + P S A+ K + + Sbjct: 105 PKPVK--KVEQPKRDVKP--VESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRAL 160 Query: 229 ERIGNLNYPDEARRQKLYGSLRLLVSINRDGTIYEVQVLESSGEPILDQAAQRIVRLAAP 288 R YP A+ ++ G +++ + DG + VQ+L + + ++ + +R Sbjct: 161 SRN-QPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMR-RWR 218 Query: 289 YAP 291 Y P Sbjct: 219 YEP 221
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.9 bits (179), Expect = 3e-18 Identities = 32/117 (27%), Positives = 51/117 (43%), Gaps = 2/117 (1%) Query: 6 DGLKVMVIDDSKTIRRTAETLLKKVGCDVITAIDGFDALAKIADTHPNIIFVDIMMPRLD 65 G ++V DD IR L + G DV + IA +++ D++MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 66 GYQTCALIKNNSAFKSTPVIMLSSKDGLFDKAKGRIVGSDQYLTKPFSKEELLGAIK 122 + IK A PV+++S+++ K G+ YL KPF EL+G I Sbjct: 62 AFDLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 8e-21 Identities = 33/119 (27%), Positives = 51/119 (42%), Gaps = 2/119 (1%) Query: 2 ARILIVDDSPTEMYKLTAMLEKHGHQVLKAENGGDGVALARQEKPDVVLMDIVMPGLNGF 61 A IL+ DD L L + G+ V N D+V+ D+VMP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRQLTKDAETSAIPVIIVTTKDQETDKVWGKRQGARDYLTKPVDEETLLKTINAVLA 120 ++ K +PV++++ ++ + +GA DYL KP D L+ I LA Sbjct: 64 DLLPRIKKARPD--LPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 68.3 bits (167), Expect = 2e-13 Identities = 26/113 (23%), Positives = 54/113 (47%), Gaps = 2/113 (1%) Query: 2353 VMVVDDSVTVRKVTTRLLERNGMNVLTAKDGVDAIAQLQEHRPDILLLDIEMPRMDGFEV 2412 ++V DD +R V + L R G +V + + D+++ D+ MP + F++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 2413 ATLVRHDERLGNLPIIMITSRTGEKHRERALGIGVNQYLGKPYQETELLEAIQ 2465 ++ + +LP+++++++ +A G YL KP+ TEL+ I Sbjct: 66 LPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 30.2 bits (68), Expect = 0.014 Identities = 21/82 (25%), Positives = 34/82 (41%), Gaps = 3/82 (3%) Query: 7 PRVAVIADTSLQRHVLQQALLGHGYEVVLNADPARVDDAALECAPDLWLVDLTQQDDS-- 64 + V D + R VL QAL GY+V + ++ A + DL + D+ D++ Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 65 PLLDSLLEQD-RAPVLFGEGHA 85 LL + + PVL Sbjct: 64 DLLPRIKKARPDLPVLVMSAQN 85
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 30.5 bits (68), Expect = 0.016 Identities = 24/128 (18%), Positives = 43/128 (33%), Gaps = 6/128 (4%) Query: 171 NLSPTAR----LLVNQRIRSRYDEPSRLSLLYLAQQGRAYRGVDDRDLRAARLPGGSQVL 226 N+ P AR + V ++S D + L+ ++ R Y + D+ + G L Sbjct: 32 NIRPVARQVEGMFVQMMLKSMRDALPK-DGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGL 90 Query: 227 AEAFVKQIKTIKTKSKVSSIVQAKDGVAVKAGSETYKADYVVLAVPLKALGQIQMTPSLS 286 AE VKQ+ + + S+ A ++ L P S Sbjct: 91 AEMMVKQMTPEQPLPEEST-PAAPMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDS 149 Query: 287 GTQMSALK 294 ++ L Sbjct: 150 KAFLAQLS 157
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 47.1 bits (112), Expect = 8e-08 Identities = 24/93 (25%), Positives = 43/93 (46%), Gaps = 1/93 (1%) Query: 62 RIAEVRPQVNGIILKRLFKEGSDVKAGQQLYQIDPATYEADYQSAQANLASTQEQAQRYK 121 R E++P N I+ + + KEG V+ G L ++ EAD Q++L + + RY+ Sbjct: 95 RSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQ 154 Query: 122 LLVADQAVSKQQYADANA-AYLQSKAAVEQARI 153 +L ++K Y Q+ + E R+ Sbjct: 155 ILSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187 Score = 42.9 bits (101), Expect = 1e-06 Identities = 42/268 (15%), Positives = 93/268 (34%), Gaps = 37/268 (13%) Query: 37 EVGIVTLEAQTVTLNTELPGRTNAFRIAEVRPQVNGIILKRLFKEGSDVKAGQQLYQIDP 96 E+ + A+ +T+ + N R+ + R L + + K + Sbjct: 206 ELNLDKKRAERLTVLARINRYENLSRVEKSRLD----DFSSLLHKQAIAKHAVLEQENKY 261 Query: 97 ATYEADYQSAQANLASTQEQAQRYK--LLVADQAVSKQ---QYADANAAYLQSKAAVEQA 151 + + ++ L + + K + Q + + + + Sbjct: 262 VEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKN 321 Query: 152 RINLRYTKVLSPISGRIGRSAV-TEGALVTNGQANAMATVQQLDPIYVDVTQPSTALLRL 210 + + + +P+S ++ + V TEG +VT + M V + D + V + + + Sbjct: 322 EERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLMVIVPEDDTLEVTALVQNKDIGFI 380 Query: 211 RRELASGQLERAGDNAAKVSLKLE--DGSQYP-LEGRLE--FSEVSVDEGTGSVT--IRA 263 GQ +K+E ++Y L G+++ + D+ G V I + Sbjct: 381 N----VGQ---------NAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIIS 427 Query: 264 V------FPNPNNELLPGMFVHAQLQEG 285 + N N L GM V A+++ G Sbjct: 428 IEENCLSTGNKNIPLSSGMAVTAEIKTG 455
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1353 bits (3503), Expect = 0.0 Identities = 692/1034 (66%), Positives = 837/1034 (80%), Gaps = 3/1034 (0%) Query: 1 MSKFFIDRPIFAWVIALVIMLAGGLSILSLPVNQYPAIAPPAIAVQVSYPGASAETVQDT 60 M+ FFI RPIFAWV+A+++M+AG L+IL LPV QYP IAPPA++V +YPGA A+TVQDT Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VVQVIEQQMNGIDNLRYISSESNSDGSMTITVTFEQGTDPDIAQVQVQNKLQLATPLLPQ 120 V QVIEQ MNGIDNL Y+SS S+S GS+TIT+TF+ GTDPDIAQVQVQNKLQLATPLLPQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 EVQRQGIRVTKAVKNFLMVVGVVSTDGSMTKEDLSNYIVSNIQDPLSRTKGVGDFQVFGS 180 EVQ+QGI V K+ ++LMV G VS + T++D+S+Y+ SN++D LSR GVGD Q+FG+ Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180 Query: 181 QYSMRIWLDPAKLNSYQLTPGDVSSAIQAQNVQISSGQLGGLPAVKGQQLNATIIGKTRL 240 QY+MRIWLD LN Y+LTP DV + ++ QN QI++GQLGG PA+ GQQLNA+II +TR Sbjct: 181 QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRF 240 Query: 241 QTAEQFENILLKVNPDGSQVRLKDVADVGLGGQDYSINAQFNGSPASGIAIKLATGANAL 300 + E+F + L+VN DGS VRLKDVA V LGG++Y++ A+ NG PA+G+ IKLATGANAL Sbjct: 241 KNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANAL 300 Query: 301 DTAKAIRQTIANLEPFMPQGMKVVYPYDTTPVVSASIHEVVKTLGEAILLVFLVMYLFLQ 360 DTAKAI+ +A L+PF PQGMKV+YPYDTTP V SIHEVVKTL EAI+LVFLVMYLFLQ Sbjct: 301 DTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQ 360 Query: 361 NFRATLIPTIAVPVVLLGTFGVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 N RATLIPTIAVPVVLLGTF +LAAFG+SINTLTMFGMVLAIGLLVDDAIVVVENVERVM Sbjct: 361 NMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVM 420 Query: 421 AEEGLSPREAARKSMGQIQGALVGIAMVLSAVFLPMAFFGGSTGVIYRQFSITIVSAMAL 480 E+ L P+EA KSM QIQGALVGIAMVLSAVF+PMAFFGGSTG IYRQFSITIVSAMAL Sbjct: 421 MEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMAL 480 Query: 481 SVIVALILTPALCATMLKPIEKGDHGEHKGGFFGWFNRMFLSTTHGYERGVASILKHRAP 540 SV+VALILTPALCAT+LKP+ H E+KGGFFGWFN F + + Y V IL Sbjct: 481 SVLVALILTPALCATLLKPVSAE-HHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGR 539 Query: 541 YLLIYVVIVAGMIWMFTRIPTAFLPDEDQGVLFAQVQTPPGSSAERTQVVVDSMREYLLE 600 YLLIY +IVAGM+ +F R+P++FLP+EDQGV +Q P G++ ERTQ V+D + +Y L+ Sbjct: 540 YLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLK 599 Query: 601 KESSSVSSVFTVTGFNFAGRGQSSGMAFIMLKPWEERPGGENSVFELAKRAQMHFFSFKD 660 E ++V SVFTV GF+F+G+ Q++GMAF+ LKPWEER G ENS + RA+M +D Sbjct: 600 NEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRD 659 Query: 661 AMVFAFAPPSVRELGNATGFDLFLQDQAGVGHEVLLQARNKFLMLAAQNPA-LQRVRPNG 719 V F P++ ELG ATGFD L DQAG+GH+ L QARN+ L +AAQ+PA L VRPNG Sbjct: 660 GFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNG 719 Query: 720 MSDEPQYKLEIDDEKASALGVSLADINSTVSIAWGSSYVNDFIDRGRVKRVYLQGRPDAR 779 + D Q+KLE+D EKA ALGVSL+DIN T+S A G +YVNDFIDRGRVK++Y+Q R Sbjct: 720 LEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFR 779 Query: 780 MNPDDLSKWYVRNDKGEMVPFNAFATGKWEYGSPKLERYNGVPAMEILGEPAPGLSSGDA 839 M P+D+ K YVR+ GEMVPF+AF T W YGSP+LERYNG+P+MEI GE APG SSGDA Sbjct: 780 MLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDA 839 Query: 840 MAAVEEIVKQLPKGVGYSWTGLSYEERLSGSQAPALYALSLLVVFLCLAALYESWSIPFS 899 MA +E + +LP G+GY WTG+SY+ERLSG+QAPAL A+S +VVFLCLAALYESWSIP S Sbjct: 840 MALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 900 VMLVVPLGVIGALLATSMRGLSNDVFFQVGLLTTIGLSAKNAILIVEFAKELHE-QGKGI 958 VMLVVPLG++G LLA ++ NDV+F VGLLTTIGLSAKNAILIVEFAK+L E +GKG+ Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGV 959 Query: 959 VEAAIEACRMRLRPIVMTSLAFILGVVPLAISTGAGSGSQHAIGTGVIGGMVTATVLAIF 1018 VEA + A RMRLRPI+MTSLAFILGV+PLAIS GAGSG+Q+A+G GV+GGMV+AT+LAIF Sbjct: 960 VEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIF 1019 Query: 1019 WVPLFYVAVSTLFK 1032 +VP+F+V + FK Sbjct: 1020 FVPVFFVVIRRCFK 1033
>SECA#SecA protein signature. Length = 901 Score = 37.9 bits (88), Expect = 1e-04 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 7/108 (6%) Query: 212 IEVTPPNTTVERIEQ--RVFRLPAPQKRALLAHLVTVGAWEQ-VLVFTRTKHGANRLAEY 268 V P N + R + V+ A + +A++ + A Q VLV T + + ++ Sbjct: 409 TVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNE 468 Query: 269 LTKHGLPAAAIHG-NKSQNARTKALADFKANDVRILVATDIAARGLDI 315 LTK G+ ++ + A A A + A + +AT++A RG DI Sbjct: 469 LTKAGIKHNVLNAKFHANEAAIVAQAGYPAA---VTIATNMAGRGTDI 513
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 29.3 bits (65), Expect = 0.023 Identities = 31/124 (25%), Positives = 47/124 (37%), Gaps = 17/124 (13%) Query: 120 AGWQTLSLALPDPQSTAPVTRPAESAASASADKDA---------------SAADSASKPD 164 A W T L + A AE+ A A A++DA +A+ + S + Sbjct: 55 AKWSTAQLKKTQAEQAARAKAAAEAQAKAKANRDALTQRLKDIVNEALRHNASRTPSATE 114 Query: 165 VKGESGNA--PAPESTAQAGSGEPAQSEDQAPPPAIDPVEQRKAHAERVMARLQASIDLA 222 + + A E A + E A+ E +A A EQR+ ER A + + LA Sbjct: 115 LAHANNAAMQAEDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLA 174 Query: 223 LQHE 226 E Sbjct: 175 EAEE 178
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 63.7 bits (155), Expect = 4e-14 Identities = 31/116 (26%), Positives = 51/116 (43%), Gaps = 2/116 (1%) Query: 3 IRVLVAEDHTIVREGIKQLIGMAKDLQVVGEATNGEQLLETLRGTPCEVVLLDISMPGVN 62 +LVA+D +R + Q + A V +N L + ++V+ D+ MP N Sbjct: 4 ATILVADDDAAIRTVLNQALSRA-GYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 63 GLEAIPRIRALNEPPAILVLSMHDEAQMAARALKIGAAGYATKDSDPALLLTAIRR 118 + +PRI+ +LV+S + A +A + GA Y K D L+ I R Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>BICOMPNTOXIN#Staphylococcal bi-component toxin signature. Length = 315 Score = 28.7 bits (64), Expect = 0.028 Identities = 14/61 (22%), Positives = 24/61 (39%), Gaps = 11/61 (18%) Query: 135 KVAGSPQGWADFWDVKKFPGKRGLRWGAKYSLEFALMADGV-----APK------DVYQT 183 K+ G +++ KK + +RW +Y++ V PK +V QT Sbjct: 80 KMQGFISSRTTYYNYKKTNHVKAMRWPFQYNIGLKTNDKYVSLINYLPKNKIESTNVSQT 139 Query: 184 L 184 L Sbjct: 140 L 140
>PF05272#Virulence-associated E family protein Length = 892 Score = 33.9 bits (77), Expect = 0.001 Identities = 15/88 (17%), Positives = 26/88 (29%), Gaps = 20/88 (22%) Query: 40 LTLLGPSGSGKTTSLMMLAGFETPTAGEILLAGRSINNVPPHKRDIGMVFQNYALFPHMT 99 + L G G GK+T + L G + + + +D Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDFFSDTHFDI---------GTGKDSYEQIAGIVA---YE 646 Query: 100 VAENLAFPLSVRGMSKTDVKERVKRALS 127 ++E + + D E VK S Sbjct: 647 LSE-------MTAFRRADA-EAVKAFFS 666
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.4 bits (66), Expect = 0.032 Identities = 18/120 (15%), Positives = 35/120 (29%), Gaps = 4/120 (3%) Query: 334 LGSASRAFEL--APSVSWPAF-RLGNVRARLRAVEAQ-SDAALARYQRSLLLAQEDVGNA 389 SR+ EL P + P NV + +Q + ++ Sbjct: 153 YQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKK 212 Query: 390 LNQLAEHQRRLVALFQSATHGANALEIANERYRAGAGSYLAVLENQRALYQIREELAQAE 449 + R+ + + L+ + A + AVLE + + EL + Sbjct: 213 RAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYK 272
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 802 bits (2072), Expect = 0.0 Identities = 316/1029 (30%), Positives = 530/1029 (51%), Gaps = 29/1029 (2%) Query: 5 DLFVRRPVLALVVSTLILLLGLFSLGKLPIRQYPLLESSTITVTTEYPGASADLMQGFVT 64 + F+RRP+ A V++ ++++ G ++ +LP+ QYP + ++V+ YPGA A +Q VT Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 QPIAQAVSSVEGIDYLSSTSVQ-GRSVVTIRMLLNRDSTQAMTETMAKVNSVRYKLPERA 123 Q I Q ++ ++ + Y+SSTS G +T+ D A + K+ LP+ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 YDSVIERSSGETTAVAYVGFSS--KTLPIPALTDYLSRVVEPMFSSIDGVAKVQTFGGQR 181 I ++ + GF S ++DY++ V+ S ++GV VQ FG Q Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 182 LAMRLWLDADRLAGRGLTASDVAEAIRRNNYQAAPG------MVKGQYVLSNVRVNTDLT 235 AMR+WLDAD L LT DV ++ N Q A G + GQ + +++ T Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 NVDDFREMVIRNDGNG-LVRLRDVGTVELGAAATETSALMDGDPAVHLGLFPTPTGNPLV 294 N ++F ++ +R + +G +VRL+DV VELG A ++G PA LG+ N L Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 IVDGIRKLLPEIQKTLPPDVRVDLAYETSRFIQASIDEVVRTLVEALLIVVLVIYLCLGS 354 I+ L E+Q P ++V Y+T+ F+Q SI EVV+TL EA+++V LV+YL L + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 LRSVLIPVATIPLSMLGAAALMLAFGFSVNLLTLLAMVLAIGLVVDDAIVVVENVHRHIE 414 +R+ LIP +P+ +LG A++ AFG+S+N LT+ MVLAIGL+VDDAIVVVENV R + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EGKS-PVAAALIGAREVAGPVIAMTITLAAVYTPIGLMGGLTGALFREFALTLAGAVIVS 473 E K P A ++ G ++ + + L+AV+ P+ GG TGA++R+F++T+ A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 GVVALTLSPVMSSLLLQA-----HQNEGRMGRAAEWFFGGLTRRYGQVLEFSLGHRWLTG 528 +VAL L+P + + LL+ H+N+G F Y + LG Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 529 GLALLVCISLPLLYSMPKRELAPTEDQAAVLTAIKAPQHANLDYVELFARKLDQVYTSIP 588 + L+ + +L+ P EDQ LT I+ P A + + ++ Y Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 589 E------TVSTWIINGTDGPAASFGGINLAAWEKRERD---ASAIQSELQGKVGDVEGSS 639 + A ++L WE+R D A A+ + ++G + Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 640 IFAFQLAA--LPGSTGGLPVQMVLRSPQDYPVLYRTMEEIKQKARQSGLFVV-VDSDLDY 696 + F + A G+ G +++ ++ + L + ++ A Q +V V + Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 697 NNPVVQVRIDRAKANSLGIRMQDIGESLAVLVGENYVNRFGMEGRSYDVIPQSLRDQRFT 756 + ++ +D+ KA +LG+ + DI ++++ +G YVN F GR + Q+ R Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRML 781 Query: 757 PQALARQFVRTQDGNLVPLSTVVRVALQVEPNKLIQFDQQNAATLQAIPAPGVSMGQAVA 816 P+ + + +VR+ +G +VP S +L +++ + +Q APG S G A+A Sbjct: 782 PEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMA 841 Query: 817 FLDDVARGLPAGFSHDWQSDSRQYTQEGNTLVFAFLAALVVIYLVLAAQYESLADPLIIL 876 ++++A LPAG +DW S Q GN + VV++L LAA YES + P+ ++ Sbjct: 842 LMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVM 901 Query: 877 ITVPLSICGALLPLALGYATMNIYTQIGLVTLIGLISKHGILMVEFANELQLHERLDRRA 936 + VPL I G LL L ++Y +GL+T IGL +K+ IL+VEFA +L E Sbjct: 902 LVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVE 961 Query: 937 AILRAAQIRLRPVLMTTAAMVFGLVPLLFASGAGAASRFGLGVVIVSGMLVGTLFTLFVL 996 A L A ++RLRP+LMT+ A + G++PL ++GAG+ ++ +G+ ++ GM+ TL +F + Sbjct: 962 ATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021 Query: 997 PTVYTLLAR 1005 P + ++ R Sbjct: 1022 PVFFVVIRR 1030 Score = 92.6 bits (230), Expect = 4e-21 Identities = 69/327 (21%), Positives = 135/327 (41%), Gaps = 13/327 (3%) Query: 701 VQVRIDRAKANSLGIRMQDIGESLAV----LVGENYVNRFGMEGRSYDVIPQSLRDQRFT 756 +++ +D N + D+ L V + + G+ + + + + Sbjct: 184 MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIA-QTRFKN 242 Query: 757 PQALARQFVRT-QDGNLVPLSTVVRVALQVEP-NKLIQFDQQNAATLQAIPAPGVSMGQA 814 P+ + +R DG++V L V RV L E N + + + + AA L A G + Sbjct: 243 PEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALDT 302 Query: 815 V----AFLDDVARGLPAGFSHDWQSDSRQYTQEG-NTLVFAFLAALVVIYLVLAAQYESL 869 A L ++ P G + D+ + Q + +V A+++++LV+ +++ Sbjct: 303 AKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQNM 362 Query: 870 ADPLIILITVPLSICGALLPLALGYATMNIYTQIGLVTLIGLISKHGILMVEFANELQLH 929 LI I VP+ + G LA ++N T G+V IGL+ I++VE + + Sbjct: 363 RATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMME 422 Query: 930 ERLDRRAAILRAAQIRLRPVLMTTAAMVFGLVPLLFASGAGAASRFGLGVVIVSGMLVGT 989 ++L + A ++ ++ + +P+ F G+ A + IVS M + Sbjct: 423 DKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSV 482 Query: 990 LFTLFVLPTV-YTLLARNHAEVDKSPR 1015 L L + P + TLL AE ++ Sbjct: 483 LVALILTPALCATLLKPVSAEHHENKG 509
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 46.4 bits (110), Expect = 1e-07 Identities = 18/106 (16%), Positives = 43/106 (40%), Gaps = 2/106 (1%) Query: 65 AGRQVQVAAEAAGRITRIAFESGQQVQQGQLLVQLNDAVEQAELIRLKAQLRNAEILHAR 124 +GR ++ + I + G+ V++G +L++L +A+ ++ ++ L A + + Sbjct: 93 SGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARL--EQ 150 Query: 125 ARKLVERNVASQEQLDNAVAARDMALGAVRQTQALIDQKAIRAPFS 170 R + +L + V + + L I+ FS Sbjct: 151 TRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196 Score = 40.2 bits (94), Expect = 9e-06 Identities = 25/134 (18%), Positives = 60/134 (44%), Gaps = 6/134 (4%) Query: 102 AVEQAELIRLKAQLRNAEILHARARKLVERNVASQ-EQLDNAVAARDMALGAVRQTQALI 160 V +++L ++++++ +A+ + +L + + + Q + + + L + Q Sbjct: 269 RVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQAS 328 Query: 161 DQKAIRAPFSGQLGIRRVH-LGQYLGVAEPVASLV-DARTLKSNFSLDESTSPELKLGQP 218 IRAP S ++ +VH G + AE + +V + TL+ + + +GQ Sbjct: 329 V---IRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQN 385 Query: 219 LEVLVDAYPGRSFP 232 + V+A+P + Sbjct: 386 AIIKVEAFPYTRYG 399
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 738 bits (1906), Expect = 0.0 Identities = 267/868 (30%), Positives = 411/868 (47%), Gaps = 55/868 (6%) Query: 1 MAVASPAGGLDAPSRRIVFDAQMLALGPGGRSIDTSRFERGDVIEPGRYRLDLLLNSRWR 60 + A S + F+ + LA D SRFE G + PG YR+D+ LN+ + Sbjct: 31 FVACAFAAQAPLSSAELYFNPRFLA-DDPQAVADLSRFENGQELPPGTYRVDIYLNNGYM 89 Query: 61 GVEEVELRRQPGRESAVFCYDRGLLERAGIDLEKSARGQDRSSARDPLPEGLHCDPLERY 120 +V + V C R L G++ S + L C PL Sbjct: 90 ATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTA--------SVSGMNLLADDACVPLTSM 141 Query: 121 VPGARVKLDIAEQSVYVSVPSYYLSLDSSKTYVDPASWDSGISAALLNYNSNL-HVRENH 179 + A +LD+ +Q + +++P ++S + ++ Y+ P WD GI+A LLNYN + V+ Sbjct: 142 IHDATAQLDVGQQRLNLTIPQAFMS-NRARGYIPPELWDPGINAGLLNYNFSGNSVQNRI 200 Query: 180 GRSATSGYAGMNAGFNFGRARLRHNGTATWSRRMGS-----HYQRSATYVQTDLPAWRAQ 234 G ++ Y + +G N G RLR N T +++ S +Q T+++ D+ R++ Sbjct: 201 GGNSHYAYLNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSR 260 Query: 235 LLLGENSTSSEFFDAVSFRGVQLSSDDRMLPDSLRYYAPVVRGTASTNARVSVYQRGYLI 294 L LG+ T + FD ++FRG QL+SDD MLPDS R +APV+ G A A+V++ Q GY I Sbjct: 261 LTLGDGYTQGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDI 320 Query: 295 YETTVAPGAFALDELQTASYGGDLEVRVTEASGEVRSFIVPFATTVQLLRPGTTRYSLTA 354 Y +TV PG F ++++ A GDL+V + EA G + F VP+++ L R G TRYS+TA Sbjct: 321 YNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITA 380 Query: 355 GRL-NDPSLERRPNMLQGVYQRGLGNDVTAYAGGAFTGSYMSGLMGAALNT-PVGGFSGD 412 G + + + +P Q GL T Y G Y + G N +G S D Sbjct: 381 GEYRSGNAQQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVD 440 Query: 413 VTLARTEVPGGDRLSGSSYRLAYSKNLPNTGTNFSLLAYRYSTGGYLGLRDAAFMQDRVE 472 +T A + +P + G S R Y+K+L +GTN L+ YRYST GY D + + Sbjct: 441 MTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGY 500 Query: 473 RGEPLE--------------SFSRLRNRLDANISQQLGNGGNLYLNGSSQRYWSGGGRAV 518 E + R +L ++QQLG LYL+GS Q YW Sbjct: 501 NIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDE 560 Query: 519 NFSVGYSNQWRDVSYSISAQRLRSQYEGFSSGDRRGETSTLFSLNLSIPLGG-------A 571 F G + + D+++++S ++ + + + +LN++IP + Sbjct: 561 QFQAGLNTAFEDINWTLSYSLTKNAW--------QKGRDQMLALNVNIPFSHWLRSDSKS 612 Query: 572 GRGSPTLSSYLTRDSNSGTQLTSGVSGMLGKRGEASYSLSASHDRDSRQTSKS---ASLD 628 + S ++ D N +GV G L + SYS+ + S S A+L+ Sbjct: 613 QWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLN 672 Query: 629 YRLPQVELGSSLSQGPGYRQLSVKAAGGLVAHSGGITAAQTLGETIGLVHAPNARGAA-A 687 YR S +QL +GG++AH+ G+T Q L +T+ LV AP A+ A Sbjct: 673 YRGGYGNANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVE 732 Query: 688 GYSGSRIDRHGYAVIPNLLPYQLNSVDLDPNGMADEIELRSSSRNVAPTAGAVVRLDYPT 747 +G R D GYAV+P Y+ N V LD N +AD ++L ++ NV PT GA+VR ++ Sbjct: 733 NQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKA 792 Query: 748 RVAKPLLVDSRMPSGEPLPFAAEVLDAHSGQSVGAVGQGSRLVLRVEQDRGSVRVRWGNE 807 RV LL+ + +PLPF A V S QS G V ++ L G V+V+WG E Sbjct: 793 RVGIKLLMTLT-HNNKPLPFGAMVTSE-SSQSSGIVADNGQVYLSGMPLAGKVQVKWGEE 850 Query: 808 PQQQCLVDYALGPRETTPPVLQLA--CR 833 C+ +Y L P + QL+ CR Sbjct: 851 ENAHCVANYQLPPESQQQLLTQLSAECR 878
>PF05860#haemagglutination activity domain. Length = 117 Score = 79.5 bits (196), Expect = 7e-20 Identities = 31/108 (28%), Positives = 49/108 (45%), Gaps = 9/108 (8%) Query: 54 LPSGGTVVGGSANGEIHLSGGNSLSVNQKVDKLIANWDSFSVAAGERVIFNQPSSSSIAL 113 LP + I Q L ++ FSV FN P++ + Sbjct: 9 LPINSNITTEGNTRII-------ERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNII 61 Query: 114 NRVIGTKASDIQGRIDANG--QVFLVNPNGVLFGRGAQVNVGGLVAST 159 +RV G S+I G I AN +FL+NPNG++FG+ A++++GG + Sbjct: 62 SRVTGGSVSNIDGLIRANATANLFLINPNGIIFGQNARLDIGGSFVGS 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 56.4 bits (136), Expect = 1e-11 Identities = 30/126 (23%), Positives = 54/126 (42%), Gaps = 5/126 (3%) Query: 5 RIRVMVADDHPAISLGISYELSQCGSLEMLGQVSNSTELIGRLNEGDCDVVIVDYTMPGG 64 ++VADD AI ++ LS+ G + SN+ L + GD D+V+ D MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAG--YDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 65 KYGDGLALLSLLRRRYPHLQLVVFTMLNNPGLIRAILKQGINCILSKSDSTSHLLAAVSA 124 + LL +++ P L ++V + N ++G L K + L+ + Sbjct: 61 ---NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117 Query: 125 AYSRNQ 130 A + + Sbjct: 118 ALAEPK 123
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 64.3 bits (156), Expect = 2e-14 Identities = 42/190 (22%), Positives = 72/190 (37%), Gaps = 9/190 (4%) Query: 3 NVLIVGASRGIGLGLADAFLQRGAQVFAVARRPQGSPGLQALAERAGERLQAVTGDLNQH 62 I GA++GIG +A +GA + AV P+ + + + +A D+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 63 DCAERIGEMLGER--RIDRLIVNAGIYGPQQQDVAEIDAEQTAQLFLTNAIAPLRLARAL 120 + I + ID L+ AG+ P + E+ F N+ +R++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIH--SLSDEEWEATFSVNSTGVFNASRSV 127 Query: 121 SG--RVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLL 178 S R G + + S A + +M Y +SKAA + E E + Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVP---RTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 179 LHPGWVRTEM 188 + PG T+M Sbjct: 185 VSPGSTETDM 194
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 44.8 bits (106), Expect = 9e-07 Identities = 49/199 (24%), Positives = 80/199 (40%), Gaps = 29/199 (14%) Query: 621 ILLTGASGLMGAHLLAELLASREADLHCPVRAQNDAHALERLRQAARQHRIELAETDWRR 680 L+TGA+G +G H+ LL + ND + + +Q R+EL Sbjct: 3 YLVTGAAGFIGFHVSKRLL--EAGHQVVGIDNLNDYYDVSL-----KQARLELLAQP--G 53 Query: 681 VRAYAADLAEPGFGLPAETYRELAGSVDQVFHSA--SAVNF-IQ-PYSYMKRDNVEGLGQ 736 + + DLA+ + + G ++VF S AV + ++ P++Y N+ G Sbjct: 54 FQFHKIDLAD--REGMTDLFAS--GHFERVFISPHRLAVRYSLENPHAYADS-NLTGFLN 108 Query: 737 VLRFCASGRCKPLMLLSSISVYSWGHLHTGKRLMREDDDIDQNLPAVVTDMGYVRSKWVM 796 +L C + + L+ SS SVY K DD +D P + Y +K Sbjct: 109 ILEGCRHNKIQHLLYASSSSVYGLNR----KMPFSTDDSVDH--PVSL----YAATKKAN 158 Query: 797 EKIADLAAE-RGLPLMTFR 814 E +A + GLP R Sbjct: 159 ELMAHTYSHLYGLPATGLR 177
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 45.8 bits (108), Expect = 2e-08 Identities = 47/198 (23%), Positives = 68/198 (34%), Gaps = 33/198 (16%) Query: 11 SQVALLIVDLQRGMQRHDLPPRNNPGAE--ARIVELLAAWRAAGWPVVHVRHVSRQPGSP 68 ++ LLI D+Q +P E A I +L G PVV+ + QPGS Sbjct: 29 NRAVLLIHDMQNYFVDA-FTAGASPVTELSANIRKLKNQCVQLGIPVVY----TAQPGSQ 83 Query: 69 -----------FAPGQPG----VEFQPALAPRDDEAVFEKNVPDAFINSGLQRWLHVRDI 113 + PG + LAP DD+ V K AF + L + Sbjct: 84 NPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEGR 143 Query: 114 RQVALVGVATENSVEASARSAGNLGFQTWVVADACFTFAKPDFHGTPRSADEVHAMALAN 173 Q+ + G+ +A A + + V DA F+ H MAL Sbjct: 144 DQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSLEK-----------HQMALEY 192 Query: 174 LHGEYAVVLRAAELLQRL 191 G A + LL +L Sbjct: 193 AAGRCAFTVMTDSLLDQL 210
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 32.3 bits (73), Expect = 0.003 Identities = 24/104 (23%), Positives = 35/104 (33%), Gaps = 16/104 (15%) Query: 352 EVELLAAIETLIGQTLQRREEPDFEPEHRVPQTA----PGGVVLKKPKKPKKPKAAESVG 407 V ++ + Q +Q EP EPE VV++KPK KPK Sbjct: 46 SVTMVTPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKK 105 Query: 408 ---------KPGKIHLGSWFDSSAP---TVKAVRKAPGFGAGAA 439 KP + S F+++AP T A + Sbjct: 106 VQEQPKRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSV 149
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 72.6 bits (178), Expect = 4e-17 Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 1/111 (0%) Query: 3 TVLIVDDHPVIRLAVRVLLEKHGLQVVAETDNGVDAIQLVREHEPDVVILDIGIPKLDGL 62 T+L+ DD IR + L + G V T N + + + D+V+ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 TVISRIKSLGLRSQVLVLTSQSAEAFCKRCIQVGARGFVNKEEDLNNLINA 113 ++ RIK VLV+++Q+ + + GA ++ K DL LI Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGI 114
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 52.9 bits (127), Expect = 1e-09 Identities = 27/140 (19%), Positives = 51/140 (36%), Gaps = 9/140 (6%) Query: 1 MNDLNVLVLEDEPFQRLVAVTALKKVVPGSILEAADGKEAVAILESCGHVDIAICDLQMS 60 M +LV +D+ R V AL + + ++ + + G D+ + D+ M Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRA-GYDVRITSNAATLWRWIAA-GDGDLVVTDVVMP 58 Query: 61 GMDGLAFLRHASLSGKVHSVILSSEVDPILRQATI-SMIECLGLNFLGDLGKPFSLERIT 119 + L + V++ S Q T + I+ L KPF L + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSA------QNTFMTAIKASEKGAYDYLPKPFDLTELI 112 Query: 120 ALLTRYNARRQDLPRQIEVA 139 ++ R A + P ++E Sbjct: 113 GIIGRALAEPKRRPSKLEDD 132
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 64.1 bits (156), Expect = 2e-12 Identities = 31/112 (27%), Positives = 49/112 (43%), Gaps = 5/112 (4%) Query: 957 RLQVLVVDDHAVNRQILHQQLSFLGHDVEEAENGLSALNLWHGQPFDMVITDCHMPLMSG 1016 +LV DD A R +L+Q LS G+DV N + D+V+TD MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 1017 SDLARSIRQEERENGEEPVVIIGLTADAQPEEIERCIQAGMNECLIKPIGLD 1068 DL I+ + + PV+++ +A + + G + L KP L Sbjct: 63 FDLLPRIK---KARPDLPVLVM--SAQNTFMTAIKASEKGAYDYLPKPFDLT 109
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 88.6 bits (219), Expect = 6e-23 Identities = 55/180 (30%), Positives = 82/180 (45%), Gaps = 7/180 (3%) Query: 5 VAFVTGCSSGIGRALADAFQRAGYRVWA----SARKEDDVRALAEAGFQAVQ--LDVNDA 58 +AF+TG + GIG A+A G + A + E V +L A DV D+ Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 59 AALARLAEELEVEAAGLDVLVNNAGYGAMGPLLDGGVEAMRRQFETNVFAVVGVTRALFP 118 AA+ + +E E +D+LVN AG G + E F N V +R++ Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 119 -LLRRKSGLVVNVGSVSGVLVTPFAGAYCASKAAVHALSDALRLELAPFGVEVLEVQPGA 177 ++ R+SG +V VGS + AY +SKAA + L LELA + + V PG+ Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.9 bits (197), Expect = 1e-19 Identities = 44/197 (22%), Positives = 76/197 (38%), Gaps = 18/197 (9%) Query: 13 RLLLVDDHPMMRKGVAQLLELEDDLSVVGEAGSGEEALRLAAELDPDMILLDLNMKGMNG 72 +L+ DD +R + Q L V + R A D D+++ D+ M N Sbjct: 5 TILVADDDAAIRTVLNQALSRAG-YDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 73 LDTLRALREAGVDARIVVFTVSDDKGDVVNVLRAGADGYLLKDMEPERLLEHIRQAATGQ 132 D L +++A D ++V + + + GA YL K + L+ I +A Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA-- 120 Query: 133 MTLSPQLTQILAQALRGDD---RSKSLDELTERERQILRQIAHGYSNKMIARKLDITE-G 188 + +++ + G RS ++ E+ ++L ++ MI E G Sbjct: 121 -EPKRRPSKLEDDSQDGMPLVGRSAAMQEI----YRVLARLMQTDLTLMI-----TGESG 170 Query: 189 TVKVHVKRVLHKLGMRS 205 T K V R LH G R Sbjct: 171 TGKELVARALHDYGKRR 187
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 2e-06 Identities = 26/111 (23%), Positives = 48/111 (43%), Gaps = 12/111 (10%) Query: 495 FGERGEVTIELDNRLQHVPLSPNEEIHVLQIVREALSNVVRHSQAQR---AWVRLSSQAD 551 F +R + +++ + V + P ++Q + E N ++H AQ + L D Sbjct: 236 FEDRLQFENQINPAIMDVQVPP----MLVQTLVE---NGIKHGIAQLPQGGKILLKGTKD 288 Query: 552 -GQVSIAVEDDGVGFDPQQNRSGHYGLTIMQERGQTL-GSQLRFEARAPHG 600 G V++ VE+ G S GL ++ER Q L G++ + + G Sbjct: 289 NGTVTLEVENTGSLALKNTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQG 339
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 39.0 bits (91), Expect = 3e-05 Identities = 60/350 (17%), Positives = 113/350 (32%), Gaps = 30/350 (8%) Query: 39 ELGLSESQ---FGLMVALPILTGSLVRLPLGLITDRFGGRIVFFIHMLLVAIPIYGLAFA 95 +L S +G+++AL L LG ++DRFG R V + + A+ +A A Sbjct: 34 DLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATA 93 Query: 96 SQYWHYLVLGLFVGLAGGSFAVGIAYTSAWFEKERQGTAMGIFGAGNAGAAITNLVAPMI 155 W + + G+ G + AV AY + + + + G A + V + Sbjct: 94 PFLWVLYIGRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAGPVLGGL 153 Query: 156 VVAFGWRMVPQVYSVAMLVTAVLFWLFTWTDPAHLKGAAEASQRPTLAKQLAPLAELRVW 215 + F P + A+ L F + + + + V Sbjct: 154 MGGFSPHA-PFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVV 212 Query: 216 RFGLYYFFVFG--GFVALALWLPKYYIAEYGLDLKTASFITMLFTLPSGLIRA-LGGWFS 272 + FF+ G V ALW+ + + D T F + L +A + G + Sbjct: 213 AALMAVFFIMQLVGQVPAALWV-IFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVA 271 Query: 273 DHYGARS-VNWGVFWVCLVCLFFLSYPQTTMTIHGIQGDLSLGIGLNVWLFTFLVFVVGI 331 G R + G+ + + W+ F + V+ Sbjct: 272 ARLGERRALMLGMIADGTGYILLAFATR-------------------GWMA-FPIMVLLA 311 Query: 332 AQGFGKASVYRIIHDYYPSN-MGTVGGMVGVIGGLGGFCLPILFGYAADH 380 + G G ++ ++ G + G + + L P+LF Sbjct: 312 SGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAA 361
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.2 bits (68), Expect = 0.019 Identities = 28/128 (21%), Positives = 47/128 (36%), Gaps = 11/128 (8%) Query: 52 AVWMIWSTVTVRLNSAGFAFSNDQLFLLAALPSISGATLRVFYSFMVPIFGGRRWTALST 111 A+W+I+ ++ S L L S++ A + + G RR L Sbjct: 231 ALWVIFGEDRFHWDATTIGIS---LAAFGILHSLAQA---MITGPVAARLGERRALMLGM 284 Query: 112 ASMLIPCIWLGFAVQDPSTPYWVFALIALLCGFGGGNFASSMSNISFFYPKSQQGTALGL 171 + I L FA + W+ I +L GG + + +S + +QG G Sbjct: 285 IADGTGYILLAFATR-----GWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGS 339 Query: 172 NAGLGNLG 179 A L +L Sbjct: 340 LAALTSLT 347
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 399 bits (1027), Expect = e-136 Identities = 138/488 (28%), Positives = 206/488 (42%), Gaps = 59/488 (12%) Query: 51 GAGGADELKAIRSTTLPNGKQVTRYEQFHNGVRVVGEAITEVKGPGKSVAAQRSGHFVAN 110 G + L I + G V R+EQ +G + G+ + SG + N Sbjct: 69 GGQARERLSLIGNKLDELGHTVMRFEQAIAASLCMGAVLVAHVNDGE--LSSLSGTLIPN 126 Query: 111 IAADLPGSTTAAVSAEQVLAQAKS------LKAQGRKTENDKVELVIRLGENNIAQLVYN 164 + T AA+S +Q AK K + E LVI E +L Y Sbjct: 127 LDKRTL-KTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEET-PRLAYE 184 Query: 165 VSYLIPGEGLSRPHFVIDAKTGEVLDQWEGLAHAEAGGPG---------------GNQKI 209 V+ ++IDA G+VL++W + A+ GG G+QK Sbjct: 185 VNVRFLTPVPGNWIYMIDAADGKVLNKWNQMDEAKPGGAQPVAGTSTVGVGRGVLGDQKY 244 Query: 210 GKYTYGSDYGPLIVNDRCEMDDGNVITVDMNSSTDDSKTTPFRFACPTNTYKQVNGAYSP 269 TY S YG + D + T D + T + + Q +Y Sbjct: 245 INTTYSSYYGYYYLQDNTR--GSGIFTYDGRNRTVLPGSLW------ADGDNQFFASYDA 296 Query: 270 -LNDAHFFGGVVFKLYRDWFG---TSPLTHKLYMKVHYGRSVENAYWDGTAMLFGDG-AT 324 DAH++ GVV+ Y++ G + VHYGR NA+W+G+ M++GDG Sbjct: 297 AAVDAHYYAGVVYDYYKNVHGRLSYDGSNAAIRSTVHYGRGYNNAFWNGSQMVYGDGDGQ 356 Query: 325 MFYPLV-SLDVAAHEVSHGFTEQNSGLIYRGQSGGMNEAFSDMAGEAAEFYMRGKNDFLI 383 F P +DV HE++H T+ +GL+Y+ +SG +NEA SD+ G EFY D+ I Sbjct: 357 TFLPFSGGIDVVGHELTHAVTDYTAGLVYQNESGAINEAMSDIFGTLVEFYANRNPDWEI 416 Query: 384 GYDIKK---GSGALRYMDQPSRDGRSIDNASQYYNGID----VHHSSGVYNRAFYLLANS 436 G DI ALR M P++ G D+ S+ Y G VH +SG+ N+A YLL+ Sbjct: 417 GEDIYTPGVAGDALRSMSDPAKYGDP-DHYSKRYTGTQDNGGVHTNSGIINKAAYLLSQG 475 Query: 437 --------PGWDTRKAFEVFVDANRYYWTATSNYNSGACGVIRSAQNRNYS----AADVT 484 G K ++F A YY T TSN++ +++A + S V Sbjct: 476 GVHYGVSVTGIGRDKMGKIFYRALVYYLTPTSNFSQLRAACVQAAADLYGSTSQEVNSVK 535 Query: 485 RAFSTVGV 492 +AF+ VGV Sbjct: 536 QAFNAVGV 543
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 63.5 bits (154), Expect = 1e-14 Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 5/96 (5%) Query: 10 ERGRQRRRAMLDAATQAFLEHGFEGTTLDMVIERAGGSRGTLYSSFGGKEGLFAAVIA-- 67 + ++ R+ +LD A + F + G T+L + + AG +RG +Y F K LF+ + Sbjct: 7 QEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELS 66 Query: 68 --HMIEEIFDDSADQPR-PAATLSATLEHFGRRFLT 100 ++ E + A P P + L L H +T Sbjct: 67 ESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT 102
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 60.7 bits (147), Expect = 3e-12 Identities = 63/379 (16%), Positives = 130/379 (34%), Gaps = 55/379 (14%) Query: 40 IALPSLQRSFGGDLAALSWIMSAFPFVGVFGGIAAGLLVRRWGDRRLLTVGLAILGGASL 99 ++LP + F A+ +W+ +AF G G L + G +RLL G+ I S+ Sbjct: 35 VSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSV 94 Query: 100 LGASMQDFA-WLLATRFVEGLGFLIVVVAAPAVLHRITSETRRSVVFGLWSTFMAGGIAL 158 +G F L+ RF++G G V+ R + R FGL + +A G + Sbjct: 95 IGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGV 154 Query: 159 SMLFGPLLADW-RADWQLSALLVLVAALLLPLSVPADDGCRAAGVRPAGLGTLLKVPAIT 217 G ++A + + L ++ + + + + + G+ +L I Sbjct: 155 GPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGI--ILMSVGIV 212 Query: 218 LLALGFTTYNLQFFALMTF----------------------------------------- 236 L T+Y++ F + Sbjct: 213 FFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTV 272 Query: 237 -----LPVFLMQR---LGVALETAGLIGAAIVAANALGNVAAGFILSRGIRPGALLASTA 288 + ++M+ L A + +I ++ G + + RG + T Sbjct: 273 AGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTF 332 Query: 289 ILMGLTGAAFFHAAMPGLLAIALGFVFSAVAGMLPTTVLATAPLASPAPSLTPLAIGWVM 348 + + A+F + I + FV ++ TV++T +S + + Sbjct: 333 LSVSFLTASFLLETTSWFMTIIIVFVLGGLSFT--KTVISTIVSSSLKQQEAGAGMSLLN 390 Query: 349 QGNYLGQVIGPLLIGLIVS 367 ++L + G ++G ++S Sbjct: 391 FTSFLSEGTGIAIVGGLLS 409
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 80.4 bits (198), Expect = 5e-22 Identities = 42/104 (40%), Positives = 59/104 (56%), Gaps = 2/104 (1%) Query: 5 LQIEDLLLGDGKEVVKGALITTQYKGTLEDGTLFDSSYERGRPFQCVIGTGRVIKGWDQG 64 LQ + + G G + K +T +Y GTL DGT+FDS+ + G+P +VI GW + Sbjct: 128 LQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKP--ATFQVSQVIPGWTEA 185 Query: 65 LMGMKVGGKRRLFVPSHLAYGERQVGAHIKPHSNLLFEIELLEV 108 L M G +FVP+ LAYG R VG I P+ L+F+I L+ V Sbjct: 186 LQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 61.4 bits (149), Expect = 3e-13 Identities = 28/130 (21%), Positives = 57/130 (43%), Gaps = 11/130 (8%) Query: 2 KTRVILVDDHALTLIGMRYLLSAYD-DLRIVAQAQDADGLLAQLEAHPCDLLITDLMMPG 60 +++ DD A + LS D+RI + A + A DL++TD++MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATL---WRWIAAGDGDLVVTDVVMPD 59 Query: 61 SQQADGLRLVQKVRRRYPDLPIIVVTMLGNPALVSSLLKLGIHGLVSK----RGMLDDLP 116 + L+ ++++ PDLP++V++ + G + + K ++ + Sbjct: 60 ---ENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 117 KAIRHAGRRP 126 +A+ RRP Sbjct: 117 RALAEPKRRP 126
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 57.1 bits (138), Expect = 8e-11 Identities = 46/292 (15%), Positives = 103/292 (35%), Gaps = 56/292 (19%) Query: 301 VMVTGAGGSIGSELCRQIMSCSPSVLILFEHSEYNLYSIHQELERRIKRESLSVNLLPIL 360 +VTGA G IG + ++++ V+ + ++Y S+ Q + + Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQP----GFQFHK 58 Query: 361 GSVRNPERLVDVMRTWKVNTVYHAAAYKHVPIVEHNIAEGVLNNVIGTLHAVQAAVQVGV 420 + + E + D+ + V+ + V N +N+ G L+ ++ + Sbjct: 59 IDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKI 118 Query: 421 QNFVLIST---------------DKAVRPTNVMGSTKRLAEMVLQALSNESAPVLFGDRK 465 Q+ + S+ D P ++ +TK+ E++ S Sbjct: 119 QHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYS------------ 166 Query: 466 DVHHVNKTRFTMVRFGNVLGSSGS---VIPLFREQIKRGGPVTV-THPSITRYFMTIPEA 521 H+ T +RF V G G + F + + G + V + + R F I + Sbjct: 167 ---HLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDI 223 Query: 522 AQLVIQA----------GSMGQGGD--------VFVLDMGPPVKILELAEKM 555 A+ +I+ ++ G V+ + PV++++ + + Sbjct: 224 AEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQAL 275
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 104 bits (261), Expect = 3e-26 Identities = 88/403 (21%), Positives = 164/403 (40%), Gaps = 21/403 (5%) Query: 8 AFMAVLDIQITNSSLKDIQGALAATLEEGSWISTSYLVAEIIMIPMTAWLVQLLSARRLA 67 +F +VL+ + N SL DI +W++T++++ I + L L +RL Sbjct: 23 SFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLL 82 Query: 68 VMISVGFLVSSLLCSFAWNLESMIVF-RAMQGFTGGALIPLAFTLALVKLPEHHRPKGMA 126 + + S++ + S+++ R +QG A L + +P+ +R K Sbjct: 83 LFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFG 142 Query: 127 LFAITATFAPSIGPTLGGWLTENFGWEYIFYINVPPGLLMIAGLLYGLEKKAPHWELLKS 186 L +GP +GG + W Y+ I + ++ + L+ L+K+ Sbjct: 143 LIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMIT-IITVPFLMKLLKKEVRIKGHF-- 199 Query: 187 TDYAGIVTLGIGLGCLQVFLEEGHRKDWLESQLIVSLGSVALFSLVLFVILQLSRPNPLI 246 D GI+ + +G+ +F + S LIVS + S ++FV +P + Sbjct: 200 -DIKGIILMSVGIVFFMLFT-----TSYSISFLIVS-----VLSFLIFVKHIRKVTDPFV 248 Query: 247 DLGILRNRNFGLASISSIGLGMGLYGSIYVLPLYLAQIQGYNAMQIGEVIMWMGIPQLFL 306 D G+ +N F + + + + G + ++P + + + +IG VI++ G + + Sbjct: 249 DPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG--TMSV 306 Query: 307 IPLVPKLMKLVSPR--LLCAAGFGLFGLAGFFSGVLNPDFAGPQFNQIQLLRALG-QPMI 363 I LV R L F F + + F I ++ LG Sbjct: 307 IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETT-SWFMTIIIVFVLGGLSFT 365 Query: 364 MVTISLIATAYLQPQDAGSASSLFNILRNLGGAIGIALLATLL 406 IS I ++ L+ Q+AG+ SL N L GIA++ LL Sbjct: 366 KTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLL 408
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 186 bits (473), Expect = 7e-57 Identities = 74/417 (17%), Positives = 144/417 (34%), Gaps = 96/417 (23%) Query: 18 RRLTVFLVAVGLIALAFFLHWWFIGRHVESTNNAYVQGEIT------RVASQLGARVEEV 71 R + F++ +IA + VE A G++T + + V+E+ Sbjct: 58 RLVAYFIMGFLVIAFI-----LSVLGQVEIV--ATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 72 LVRDNQHVDKGQLLVRLEDADF--------------KLAVERAQAT-------------- 103 +V++ + V KG +L++L +L R Q Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 104 ------------------------LATREAELAQARSKLVQQGSLIAASAADVNASQATL 139 +T + + Q L ++ + A +N + Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 140 GRAQIDLNRAEALRKPGYVS-------EERVTTLTADNHVARSQL---------AKARAD 183 + L+ +L ++ E + + V +SQL AK Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 184 LEAQRVQRDTLGAEIKRLEAQIASARTELAQAEINLSRTLIHSPISGLVGQRSAR-NGQY 242 L Q + + L ++++ I ELA+ E ++I +P+S V Q G Sbjct: 291 LVTQLFKNEILD-KLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGV 349 Query: 243 VQVGTHLLSLVPDED-IWVQANFKETQVGRMRDGQKARLTFDAFPDT---PIDGRIDSLF 298 V L+ +VP++D + V A + +G + GQ A + +AFP T + G++ ++ Sbjct: 350 VTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNIN 409 Query: 299 AASGAQFSLLPPDNATGNFTKVVQRIPVKIVFEADNPLHGRIRPGMSVEAEVELRDR 355 + D G V+ I + + + + GM+V AE++ R Sbjct: 410 LDA-------IEDQRLGLVFNVIISIEENCLSTGNKNI--PLSSGMAVTAEIKTGMR 457
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 37.7 bits (87), Expect = 3e-05 Identities = 26/152 (17%), Positives = 49/152 (32%), Gaps = 21/152 (13%) Query: 32 REDESRQVVVEAPPRPQSPAMPSVEVQPTEVPELQPGEEGNAPEI-VEEGSPAAAGQPSQ 90 + E +V + P+ + VQP P + N E + + A QP++ Sbjct: 1118 KTQEVPKVTSQVSPKQEQSE----TVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAK 1173 Query: 91 PIGGLPATPPAAQPPAQAQAPAASLPPSQPQPPAAPPSPPPAEKRLDANNLPQSW----- 145 T + P + P P+ +++N P++ Sbjct: 1174 ------ETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSV 1227 Query: 146 -----SVQLASLSNRARAEELQKTLRSQGYNA 172 +V+ A+ S+ R+ L S NA Sbjct: 1228 RSVPHNVEPATTSSNDRSTVALCDLTSTNTNA 1259
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 115 bits (288), Expect = 4e-33 Identities = 74/254 (29%), Positives = 111/254 (43%), Gaps = 18/254 (7%) Query: 10 GKVALVTGAARGIGLGISAWLIAEGWQVVLADNDRERGARVAE---ALGEHAWFVAMDVA 66 GK+A +TGAA+GIG ++ L ++G + D + E+ +V A HA DV Sbjct: 8 GKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 67 QEGQVAMSVAEVLGQFGRLDGLVCNAAIANPRNTPLEALSLGEWTRTLAVNLTGPMLLAK 126 + A + + G +D LV A + P + +LS EW T +VN TG ++ Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRP--GLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 YCTPYLRA-HNGAIVNIASTRAHQSEPDSEAYAASKGGLLALTHALAASLGP-DIRVNAL 184 + Y+ +G+IV + S A AYA+SK + T L L +IR N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 185 SPG----------WIDTREAAEREAAPLTELDHDQHLVGRVGTVEDVASLVAWLLSEDAG 234 SPG W D A + L L ++ D+A V +L+S AG Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPL-KKLAKPSDIADAVLFLVSGQAG 244 Query: 235 FVTGQEFLVDGGMT 248 +T VDGG T Sbjct: 245 HITMHNLCVDGGAT 258
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 595 bits (1535), Expect = 0.0 Identities = 217/631 (34%), Positives = 345/631 (54%), Gaps = 35/631 (5%) Query: 41 AFVPAGNQQEAHWTINLKDADIREFIDQISEITGETFVVDPRVKGQVSVVSKAQLSLSEV 100 F PA ++ ++ + K DI+EFI+ +S+ +T ++DP V+G ++V S L+ + Sbjct: 21 LFRPAAAEE---FSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQY 77 Query: 101 YQLFLSVMSTHGFTVVAQGDQA-RIVPNAEAKTEAG--GGQSAP---DRLETRVIQVQQS 154 YQ FLSV+ +GF V+ + ++V + +AKT A +AP D + TRV+ + Sbjct: 78 YQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVTRVVPLTNV 137 Query: 155 PVSELIPLIRPLVPQYGHLAAV--PSANALIISDRSANIARIEDVIRQLDQKGSHDYSVI 212 +L PL+R L G + V +N L+++ R+A I R+ ++ ++D G + Sbjct: 138 AARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTV 197 Query: 213 NLRYGWVMDAAEV---LNNAMSRGQAKGAAGAQVIADARTNRLIILGPPQARAKLVQLAQ 269 L + D ++ LN S+ G+ A V+AD RTN +++ G P +R +++ + + Sbjct: 198 PLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIK 257 Query: 270 SLDTPTARSANTRVIRLRHNDAKTLAETLGQISEGMKNNGGQGGEQTGGGRPSNILIRAD 329 LD A NT+VI L++ A L E L IS M++ + NI+I+A Sbjct: 258 QLDRQQATQGNTKVIYLKYAKASDLVEVLTGISSTMQSEKQAAKPVAALDK--NIIIKAH 315 Query: 330 ESTNALVLLADPDTVNALEDIVRQLDVPRAQVLVEAAIVEISGDIQDAVGVQWAINKGGM 389 TNAL++ A PD +N LE ++ QLD+ R QVLVEA I E+ +G+QWA GM Sbjct: 316 GQTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKNAGM 375 Query: 390 GGTKTNFANTGLSIGTLLQSLESNKAPESIP----------DGAIVGIGSSSFGALVTAL 439 T F N+GL I T + ++ +G G ++ L+TAL Sbjct: 376 ----TQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNWAMLLTAL 431 Query: 440 SANTKSNLLSTPSLLTLDNQKAEILVGQNVPFQTGSYTTNSEGSSNPFTTVERKDIGVSL 499 S++TK+++L+TPS++TLDN +A VGQ VP TGS TT+ + N F TVERK +G+ L Sbjct: 432 SSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGD---NIFNTVERKTVGIKL 488 Query: 500 KVTPHINDGAALRLEIEQEISALLPNAQQRNNT-DLITSKRSIKSTILAENGQVIVIGGL 558 KV P IN+G ++ LEIEQE+S++ A ++ + R++ + +L +G+ +V+GGL Sbjct: 489 KVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGETVVVGGL 548 Query: 559 IQDDVSQAESKVPLLGDIPLLGRLFRSTKDTHTKRNLMVFLRPTVVRDSAGLAALSGKKY 618 + VS KVPLLGDIP++G LFRST +KRNLM+F+RPTV+RD S +Y Sbjct: 549 LDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQASSGQY 608 Query: 619 SDIR-VIDGTRGPEGRPSILPTNANQLFDGQ 648 + RG E ++L + +++ Q Sbjct: 609 TAFNDAQSKQRGKENNDAMLNQDLLEIYPRQ 639
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 49.2 bits (117), Expect = 3e-09 Identities = 37/148 (25%), Positives = 57/148 (38%), Gaps = 19/148 (12%) Query: 32 APALLAVALIIAMSISLAWQAAG--WLRLQRSPVAVAASPVSHESIRSDPTRLAR--LFG 87 +P+++ L + + Q A W V++ ++ R P L LFG Sbjct: 10 SPSVIRRILFYLLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFG 69 Query: 88 TSAQDPNAPP----------PATNLDLVLKGSFVQSDPKLSSAIIQRQGDKPHRYAVGGE 137 S + N P + L+L L G D S AII + ++ V E Sbjct: 70 VS-PEKNKAGALDASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQ-FSRGVNEE 127 Query: 138 ISDG--VKLHAVYRDRVELQRGGRLESL 163 + G K+ ++ DRV LQ GR E L Sbjct: 128 V-PGYNAKIVSIRPDRVVLQYQGRYEVL 154
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 501 bits (1292), Expect = e-180 Identities = 213/406 (52%), Positives = 278/406 (68%), Gaps = 2/406 (0%) Query: 1 MAAFEYLALDPSGRQQKGVLEADSARQVRQLLRERQLAPLDVKPTRTREQSGQGGRLTFA 60 MA + Y ALD G++ +G EADSARQ RQLLRER L PL V R +Q L+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 61 RG--LSARDLALVTRQLATLVQAALPIEEALRAAAAQSTSQRIQSMLLAVRAKVLEGHSL 118 R LS DLAL+TRQLATLV A++P+EEAL A A QS + ++ AVR+KV+EGHSL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 119 AGSLREFPTAFPELYRATVAAGEHAGHLGPVLEQLADYTEQRQQSRQKIQLALLYPVILM 178 A +++ FP +F LY A VAAGE +GHL VL +LADYTEQRQQ R +IQ A++YP +L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 179 VASLAIVGFLLGYVVPDVVRVFIDSGQTLPLLTRVLIGVSDWVKAWGALAFVAAIGGVIG 238 V ++A+V LL VVP VV FI Q LPL TRVL+G+SD V+ +G +A + G + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 239 FRYALRKDAFRERWHGFLLRVPLVGRLVRSTDTARFASTLAILTRSGVPLVEALAIAAEV 298 FR LR++ R +H LL +PL+GR+ R +TAR+A TL+IL S VPL++A+ I+ +V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 299 IANRIIRNEVVKAAQKVREGASLTRSLEATGQFPPMMLHMIASGERSGELDQMLARTARN 358 ++N R+ + A VREG SL ++LE T FPPMM HMIASGERSGELD ML R A N Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 359 QENDLAAQIGLMVGLFEPFMLIFMGAVVLVIVLAILLPILSLNQLV 404 Q+ + ++Q+ L +GLFEP +++ M AVVL IVLAIL PIL LN L+ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 212 bits (541), Expect = 3e-74 Identities = 75/138 (54%), Positives = 95/138 (68%), Gaps = 3/138 (2%) Query: 10 RQQSGFTLIEIMVVVVILGILAALVVPQVMSRPDQAKVTVAKGDIKAIAAALDMYKLDNF 69 +Q GFTL+EIMVV+VI+G+LA+LVVP +M ++A A DI A+ ALDMYKLDN Sbjct: 5 DKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNH 64 Query: 70 AYPSTQQGLEALVKKPTGNPQPKNWNKDGYLKKLPVDPWGNPYQYLAPGTKGPFDLYSLG 129 YP+T QGLE+LV+ PT P N+NK+GY+K+LP DPWGN Y + PG G +DL S G Sbjct: 65 HYPTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVNPGEHGAYDLLSAG 124 Query: 130 ADGKEGGSDNDADIGNWD 147 DG+ G D DI NW Sbjct: 125 PDGEMGTED---DITNWG 139
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 143 bits (361), Expect = 3e-46 Identities = 50/183 (27%), Positives = 85/183 (46%), Gaps = 32/183 (17%) Query: 5 RGFTLIELMVVMVIISVLIGLAVLSTGFASTSRELDSEAERLAGL---IGVLTDEAVLDN 61 RGFTL+E+M++++++ V G+ +L+ SR+ DS A+ LA + + + Sbjct: 4 RGFTLLEMMLILLLMGVSAGMVLLAFP---ASRD-DSAAQTLARFEAQLRFVQQRGLQTG 59 Query: 62 REYGLRLERDAYQVLRY------DEAKA-------RWLPVARDSHRLPEWAELTFELDGQ 108 + +G+ + D +Q L D A A RWLP+ + + G Sbjct: 60 QFFGVSVHPDRWQFLVLEARDGADPAPADDGWSGYRWLPLRAGR------VATSGSIAGG 113 Query: 109 PLVLAGSKGEKEQKKGTDQPQLLILSSGELSPFRLRLAERGPEGRALSLSSDGFRLPRVE 168 L LA ++GE D P +LI GE++PFRL L E ++ ++ G LP + Sbjct: 114 KLNLAFAQGEAWTPG--DNPDVLIFPGGEMTPFRLTLG----EAPGIAFNARGESLPEPQ 167 Query: 169 VAR 171 A+ Sbjct: 168 EAQ 170
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 35.2 bits (81), Expect = 2e-05 Identities = 13/68 (19%), Positives = 30/68 (44%), Gaps = 4/68 (5%) Query: 1 MKRARGFTLLEVLVALAIF----AMVAASVLSASARSLQNASRLEDKTLAMWIADNRLNE 56 + RGFTLLE++V + I ++V +++ ++ + + + L + +L+ Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 57 LQLEQTPP 64 T Sbjct: 64 HHYPTTNQ 71
>PilS_PF08805#PilS N terminal Length = 185 Score = 35.7 bits (82), Expect = 7e-05 Identities = 11/45 (24%), Positives = 24/45 (53%) Query: 1 MRLQRGFTLLELLIAIAIFALLALATYRMFDSVMQTDQATRVQEQ 45 +G TL+E+L+ + + +LA + Y+++ V Q++ Q Sbjct: 22 KEQDKGATLMEVLLVVGVIVVLAASAYKLYSMVQSNIQSSNEQNN 66
>VACCYTOTOXIN#Helicobacter pylori vacuolating cytotoxin signature. Length = 1291 Score = 30.0 bits (67), Expect = 0.017 Identities = 18/44 (40%), Positives = 23/44 (52%), Gaps = 3/44 (6%) Query: 236 GQAENIVAARGREGFQEKTEFSKHLNELGSKASNVNFAVGTRYF 279 G+ E IV G G+ + FS N L S A+N NF V +R F Sbjct: 1056 GEVEAIVGGFGSYGY---SSFSNQANSLNSGANNTNFGVYSRIF 1096
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 30.2 bits (68), Expect = 0.012 Identities = 10/46 (21%), Positives = 16/46 (34%), Gaps = 7/46 (15%) Query: 169 PVLRDSCPPPQRAFAAQEVAAPEGVEVQPLAG-------NPHVWLS 207 ++ A +GV+V L G +PH WL+ Sbjct: 98 AWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLN 143
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 27.8 bits (61), Expect = 0.026 Identities = 23/113 (20%), Positives = 33/113 (29%), Gaps = 5/113 (4%) Query: 55 AERHLQSARQYFTEQRALHAYIQQQAPNVRQADAAAPQAQIDPAALQGMVTASAAQAGLS 114 A+R + + RA + Y +V A Q+ A S A A L Sbjct: 230 AKRKAEEQARQQAAIRAANTYAMPANGSVVATAAGRGLIQVAQGAASLAQAISDAIAVLG 289 Query: 115 VERLDNEGEGAVQVALQPAPFAKLLPWLEQLNGQ-----GVQVAEAGLDRQVD 162 AV A W +Q G+ A+ GL V+ Sbjct: 290 RVLASAPSVMAVGFASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVN 342
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 51.4 bits (123), Expect = 4e-09 Identities = 34/206 (16%), Positives = 67/206 (32%), Gaps = 18/206 (8%) Query: 165 AAVEPQRLQMAAEEQWYAAGPAAPKAPPAEPPRKQEDEQTARLAQLVKQQRQQLAALARQ 224 A +E R Q+ + P K P + +E+ RL L+K+Q Q Sbjct: 146 ARLEQTRYQILSRSIELNKLPEL-KLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQ 204 Query: 225 QEQRLAGLARQHEEELARREQDARGQLDILRSEVLSLQQALERQARENAELQQRLLEQGE 284 +E L + + R + +S + + A + +LEQ Sbjct: 205 KELNLDKKRAE-RLTVLARINRYENLSRVEKSRL----DDFSSLLHKQAIAKHAVLEQ-- 257 Query: 285 QFQRNREELTRQLRFIENQGRNETDLLRSEFADELEARVAAAVAGYKEQVSIRDVELAYR 344 + E +LR +++ + + SE + +K ++ +L Sbjct: 258 --ENKYVEAVNELR----VYKSQLEQIESEIL-SAKEEYQLVTQLFKNEILD---KLRQT 307 Query: 345 NELDQQLEQELAELRAERDRLAAQGP 370 + L ELA+ + + P Sbjct: 308 TDNIGLLTLELAKNEERQQASVIRAP 333
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 28.6 bits (63), Expect = 0.020 Identities = 16/37 (43%), Positives = 23/37 (62%), Gaps = 2/37 (5%) Query: 36 QRHPLAASRWRQEPERLAAWLREQERQPQHLAAWLAQ 72 Q+ +A + WR++ +RL AW QERQ AA LA+ Sbjct: 92 QKVDIALNSWREKKQRLQAWQTLQERQST--AALLAE 126
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 28.7 bits (64), Expect = 0.028 Identities = 13/58 (22%), Positives = 23/58 (39%), Gaps = 7/58 (12%) Query: 65 LVVVVGGDGSML----GAARALARHKVPVLGINRGSLG-FLTDIRPDELEAKVGEVLD 117 LV+ + GDG L + PV+G + SL + P ++ ++D Sbjct: 53 LVIFLSGDGGWATLDKAVGGILQQQGWPVVGWS--SLKYYWKQKDPKDVTQDTLAIID 108
>ANTHRAXTOXNA#Anthrax toxin LF subunit signature. Length = 800 Score = 30.9 bits (69), Expect = 0.008 Identities = 13/36 (36%), Positives = 19/36 (52%) Query: 231 GDIVFQPDALPEAIAREPLSEEQKSSLLTYGADEPL 266 G+I F L E + LSEE+K+S+ + G P Sbjct: 102 GEIYFTDIDLVEHKELQDLSEEEKNSMNSRGEKVPF 137
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 71.0 bits (174), Expect = 1e-14 Identities = 36/175 (20%), Positives = 77/175 (44%), Gaps = 11/175 (6%) Query: 613 IEAATNEVIKQSELII-LVLVYICVAAMCMITFRSFAATLCIVLPLILTSVLGNALMAAL 671 ++ + +EV+K L ++LV++ + + ++ ATL + + + + A++AA Sbjct: 333 VQLSIHEVVK--TLFEAIMLVFLVMY----LFLQNMRATLIPTIAVPVVLLGTFAILAAF 386 Query: 672 GIGVKVATLPVIALGVGIGVDYGIYIYTRLESFLRM-GLPLQEAYYETLRSTGKAVLFTG 730 G + T+ + L +G+ VD I + +E + LP +EA +++ A++ Sbjct: 387 GYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIA 446 Query: 731 LCLAIGVATWIF---SAIKFQADMGLMLTFMLLWNMFGALWLLPALARFLINPAK 782 + L+ F S + + + ++ AL L PAL L+ P Sbjct: 447 MVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVS 501 Score = 42.9 bits (101), Expect = 6e-06 Identities = 35/221 (15%), Positives = 80/221 (36%), Gaps = 15/221 (6%) Query: 251 LITLVLLYWFTKCIRSTIAVLITTLVAVLWQLGLLNLVGFGLDPYSMLVPFLIFAIGISH 310 ++ +++Y F + +R+T+ I V +L +L G+ ++ +M L + + Sbjct: 349 MLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDD 408 Query: 311 GVQKINGIA-LQSSGADNALMAARLTFRQLFLPGMIAILADAVGFITLLVID--IGVI-R 366 + + + + A + Q+ + + + FI + G I R Sbjct: 409 AIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYR 468 Query: 367 ELAIGASIGVAVIVFTNLILLPVAISYI--GISKKAVQRSKDDAVREHPFWRLLSNFASP 424 + +I +A+ V LIL P + + +S + + + + N + Sbjct: 469 QFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTN 528 Query: 425 KVAPV------SIAIALLMLGGGLWYGKHLKIG---DLDQG 456 V + + I L++ G + L + DQG Sbjct: 529 SVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQG 569 Score = 33.3 bits (76), Expect = 0.005 Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 5/113 (4%) Query: 626 LIILVLVYICVAAMCMITFRSFAATLCIVLPLILTSVLGNALMAALGIGVKVATLPVIAL 685 I V+V++C+AA+ + S++ + ++L + L V V + + Sbjct: 877 AISFVVVFLCLAAL----YESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLT 932 Query: 686 GVGIGVDYGIYIYTRLESFLRM-GLPLQEAYYETLRSTGKAVLFTGLCLAIGV 737 +G+ I I + + G + EA +R + +L T L +GV Sbjct: 933 TIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGV 985
>PF07675#Cleaved Adhesin Length = 1358 Score = 32.4 bits (73), Expect = 0.005 Identities = 23/88 (26%), Positives = 36/88 (40%), Gaps = 6/88 (6%) Query: 64 PAPDSYYFKGSVGTAGLPPKLREMLDTPPYKSIGAMQLLGNWDDDDEEEDDDAPSDDAYV 123 PA + G G P + + K M+ G D D E +DD+P+ Y Sbjct: 480 PASGKMWIAGDGGNQ--PARYDDFAFEAGKKYTFTMRRAGMGDGTDMEVEDDSPASYTYT 537 Query: 124 VVR--QPLADGKTLYLYDND--AAGSID 147 V R + +G T ++ D AAG+ + Sbjct: 538 VYRDGTKIKEGLTATTFEEDGVAAGNHE 565
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 84.1 bits (208), Expect = 5e-21 Identities = 30/129 (23%), Positives = 59/129 (45%) Query: 3 IHVLVVEDNFDLAGTVIDYLEAAGVVCDHARDGQAGLNLARANRYDVILLDIMLPRINGR 62 +LV +D+ + + L AG + A D+++ D+++P N Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 63 QVCRQLREAGLQTPVLMLTALDTLQDKLDGFDAGADDYLLKPFELPELLVRLQALSRRRS 122 + ++++A PVL+++A +T + + GA DYL KPF+L EL+ + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 123 GQAQRLQVD 131 + +L+ D Sbjct: 124 RRPSKLEDD 132
>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein signature. Length = 522 Score = 36.3 bits (83), Expect = 3e-04 Identities = 39/158 (24%), Positives = 72/158 (45%), Gaps = 13/158 (8%) Query: 340 LMLSLPQPAMAFQFEDLWLRPDQQGQRLLQRGQADEAAKRFEDFRWKGLSLYQARDYAAA 399 L++ P P + + L +++ + Q+ Q D+ KR E+ R K + + Sbjct: 131 LIVDAPDPK-ELEEQKKALEKEKEAKEQAQKAQKDKREKRKEE-RAKNRA-----NLENL 183 Query: 400 AQAFAQGDQADDHYNRGNALARQGELEAAVDAYEQALERQPQLVAAQRNK-ALVEELLRQ 458 A + ++ N + +Q E E +D E+ + Q Q AQ N +EEL ++ Sbjct: 184 TNAMSNPQNLSNNKNLSELIKQQRENE--LDQMERLEDMQEQ---AQANALKQIEELNKK 238 Query: 459 RQEQAAQQQAGENKEQHQEASQQSPPSGSSQRPPRDAA 496 + E+A +Q+A + + SQ+SP S + P D+A Sbjct: 239 QAEEAVRQRAKDKISIKTDKSQKSPEDNSIELSPSDSA 276
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 70.9 bits (173), Expect = 1e-16 Identities = 59/191 (30%), Positives = 92/191 (48%), Gaps = 6/191 (3%) Query: 6 IKGKTVLITGGAKNLGGLIARDLAAHGAKAIAIHYNSAASKADADATVAALQAAGAKAVA 65 I+GK ITG A+ +G +AR LA+ GA A+ YN + V++L+A A A Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKL----EKVVSSLKAEARHAEA 61 Query: 66 LQGDLTSAAAMEKLFADAIAAVGKPDIAINTVGKVLKKPITEISETEYDEMSAVNSKSAF 125 D+ +AA++++ A +G DI +N G + I +S+ E++ +VNS F Sbjct: 62 FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 126 FFLREAGKHVND--NGKICTLVTSLLGAYTPYYAAYAGTKAPVEHFTRAASKEFGARGIS 183 R K++ D +G I T+ ++ G AAYA +KA FT+ E I Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 184 VTAVGPGPMDT 194 V PG +T Sbjct: 182 CNIVSPGSTET 192
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 33.1 bits (75), Expect = 3e-04 Identities = 19/100 (19%), Positives = 29/100 (29%), Gaps = 9/100 (9%) Query: 4 APKTASKKVAPAAEQVAEPKPPAKPKPAAAPPKPASRPVAKDKPAPAKRASTARLDPEVR 63 PK S+ V+P EQ +P A+P P P ++ V Sbjct: 1122 VPKVTSQ-VSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVE 1180 Query: 64 KPLPSAKLDLRLPK-------ELVQKMAPPGTEETH-KPK 95 +P+ + P E+ KPK Sbjct: 1181 QPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK 1220
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 81.3 bits (200), Expect = 3e-20 Identities = 54/191 (28%), Positives = 85/191 (44%), Gaps = 9/191 (4%) Query: 3 LHGKTLFITGASRGIGREIALRAARDGANLVIAAKSAEPHPKLEGTIFSVAAEVEAAGGQ 62 + GK FITGA++GIG +A A GA++ + E K+ ++ + A EA Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEA---- 61 Query: 63 ALPLQLDVRDEQAVAAAMARAAERFGGIDALVNNAGAIRLVGVEKLEPKRFDLMYQINTR 122 DVRD A+ AR G ID LVN AG +R + L + ++ + +N+ Sbjct: 62 ---FPADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNST 118 Query: 123 AVLVCSQAALPYLRRSANGHILSLSPPINLAGRWFAQHGPYTVTKYGMSMLTLGMHEEFG 182 V S++ Y+ +G I+++ N AG Y +K M T + E Sbjct: 119 GVFNASRSVSKYMMDRRSGSIVTVGS--NPAGVPRTSMAAYASSKAAAVMFTKCLGLELA 176 Query: 183 KYAISVNALWP 193 +Y I N + P Sbjct: 177 EYNIRCNIVSP 187
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 37.5 bits (87), Expect = 2e-04 Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Query: 579 AGASAQVGASSGTLK-APMDGAIV-EVLVGEGERVGKGQLLLVLEAMKMEHPLKAGVDGV 636 A A+ ++ S + + P++ +IV E++V EGE V KG +LL L A+ E A Sbjct: 84 ATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAE----ADTLKT 139 Query: 637 VRRVQVGRGEQVRNRQVLVEVEADA 661 + R EQ R + + +E + Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNK 164
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 119 bits (299), Expect = 3e-34 Identities = 74/255 (29%), Positives = 121/255 (47%), Gaps = 10/255 (3%) Query: 13 DGQTIIVTGGGSGIGRCTAHELAALGAHVVLVGRKAEKLEKTAGEIVEDGGSVSWHACDI 72 +G+ +TG GIG A LA+ GAH+ V EKLEK + + D+ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 73 REEEAVKTLVANILAERGTIHHLVNNAGGQYPSPLASISQKGFETVLRTNLVGGFLVARE 132 R+ A+ + A I E G I LVN AG P + S+S + +E N G F +R Sbjct: 67 RDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS 126 Query: 133 VFNQSMSKTGGSIVNMLADMWGGMP--GMGHSGAARSGMENFTRTAAVEWGHAGVRVNAV 190 V M + GSIV + ++ G+P M ++++ FT+ +E +R N V Sbjct: 127 VSKYMMDRRSGSIVTVGSNP-AGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 191 APG-------WIASSGMDTYEGAFKAVIPTLREHVPLKRIGSESEVAAAIVFLLSPGAAF 243 +PG W + + E K + T + +PLK++ S++A A++FL+S A Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 244 VSGNTIRIDGAASQG 258 ++ + + +DG A+ G Sbjct: 246 ITMHNLCVDGGATLG 260
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 33.8 bits (77), Expect = 5e-04 Identities = 22/121 (18%), Positives = 42/121 (34%) Query: 116 LTPLLAAFFNAMLGYLVLCIFLLFSGVEPGWQLVLLPLALLPFLLCVTGLAWFLAGLGVY 175 L + A A L + + G L+ + L L + L Sbjct: 115 LGEMAWAATKAALAGAGIGVVAAALGYTQWLSLLYALPVIALTGLAFASLGMVVTALAPS 174 Query: 176 VRDIGQFVQFLLVLLLFISPVFYPLSSLPPVMQPYLYLNPLTIPVEMVRAILFDAPYPTL 235 + ++ +LF+S +P+ LP V Q PL+ ++++R I+ P + Sbjct: 175 YDYFIFYQTLVITPILFLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPVVDV 234 Query: 236 G 236 Sbjct: 235 C 235
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 185 bits (471), Expect = 9e-57 Identities = 104/404 (25%), Positives = 187/404 (46%), Gaps = 11/404 (2%) Query: 2 NFIYQAVDRKGRRVRGELCLPTRQDALRQLQRQGLTPLSLEVKR----------RNLGSR 51 + YQA+D +G++ RG + + A + L+ +GL PLS++ R +L + Sbjct: 3 QYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRK 62 Query: 52 RRLKAEELNMAIHELATMLAAGVSMADAVEAQERGARHPKLITALQAMANGLRQGQSFPV 111 RL +L + +LAT++AA + + +A++A + + P L + A+ + + +G S Sbjct: 63 IRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLAD 122 Query: 112 VLESAGLDLPRYVYQLVAAGEMTGNLAGALRDCATQMEYERRTRAELQGALIYPAILVLS 171 ++ R +VAAGE +G+L L A E ++ R+ +Q A+IYP +L + Sbjct: 123 AMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVV 182 Query: 172 GVLAVATLFVFVVPKFANLLNET-AQLPWLAWAVLSIGVWSNESSGLLAFAVLLLAGGIA 230 + V+ L VVPK LP ++ + + A+L Sbjct: 183 AIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFR 242 Query: 231 VALRNPALRAHALDQLVRLPVVGEWLMQAEIAQWSKVLGTLLGNRVPLVEALLLSAAGVR 290 V LR R +L+ LP++G A++++ L L + VPL++A+ +S + Sbjct: 243 VMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDVMS 302 Query: 291 IARQRRTLERVTQDVRAGIALSAALEERQAVTSIGSSLVRVGEASGQLAEMLQSLATLYG 350 R L T VR G++L ALE+ + ++ GE SG+L ML+ A Sbjct: 303 NDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADNQD 362 Query: 351 EAGQARMKKALVLIEPLAILLIGSVFGLIITGVVLAITSANDMV 394 ++M AL L EPL ++ + +V I+ ++ I N ++ Sbjct: 363 REFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 118 bits (297), Expect = 3e-37 Identities = 47/128 (36%), Positives = 67/128 (52%), Gaps = 1/128 (0%) Query: 6 QQGFTLLEMIVVLVIIGMLMGLVGPRLFNQADKAKAQTADTQVKMLKGALLTMRLDIGRL 65 Q+GFTLLE++VV+VIIG+L LV P L +KA Q A + + L+ AL +LD Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66 Query: 66 PTEEEGLALLNTPPSDERLGAFWHGPYLEGGVPLDPWNRPYLYSDRPSAEQPFTLYSQGA 125 PT +GL L P+ L A ++ +P DPW Y+ + P + L S G Sbjct: 67 PTTNQGLESLVEAPTLPPLAANYNKEGYIKRLPADPWGNDYVLVN-PGEHGAYDLLSAGP 125 Query: 126 DGQPGGKG 133 DG+ G + Sbjct: 126 DGEMGTED 133
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 38.7 bits (90), Expect = 1e-06 Identities = 17/43 (39%), Positives = 31/43 (72%) Query: 12 QAAFTLLELLVVLVIVGAIAAVALPGLVRMQETWARRTALDDL 54 Q FTLLE++VV+VI+G +A++ +P L+ +E ++ A+ D+ Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDI 49
>PilS_PF08805#PilS N terminal Length = 185 Score = 29.5 bits (66), Expect = 0.003 Identities = 5/31 (16%), Positives = 16/31 (51%) Query: 7 GFTLLEAVVALTLLAVVGGALFAWLNSAFRS 37 G TL+E ++ + ++ V+ + + + + Sbjct: 27 GATLMEVLLVVGVIVVLAASAYKLYSMVQSN 57
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 29.9 bits (67), Expect = 0.004 Identities = 14/48 (29%), Positives = 30/48 (62%), Gaps = 2/48 (4%) Query: 7 KQGAFTLLEMIVVLLVVSFIGTLLMQGLSYASKANQSLHQSLGRGQVR 54 +Q FTLLEM+++LL++ +++ L++ + + S Q+L R + + Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVL--LAFPASRDDSAAQTLARFEAQ 47
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 28.6 bits (63), Expect = 0.005 Identities = 24/84 (28%), Positives = 33/84 (39%), Gaps = 10/84 (11%) Query: 21 LEKLKSDSSLKQELEFKDKLQALMDKYGMTLHNIIAILDPKAPVTVSAAPQRRA------ 74 +E L + ++K E LQ M+ +I A KA +A +R+A Sbjct: 181 MEGLTAAYNVKLFTEAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQ 240 Query: 75 ----RALKVYKNPNNGEVVETKGG 94 RA Y P NG VV T G Sbjct: 241 QAAIRAANTYAMPANGSVVATAAG 264
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 387 bits (995), Expect = e-132 Identities = 134/369 (36%), Positives = 197/369 (53%), Gaps = 16/369 (4%) Query: 164 ERMRDLTRRAEDEHQRAEAYLEAAGERPREMIGQSAAHKALLEEIRLVANSDLSVLITGE 223 + + RA E +R + LE + ++G+SAA + + + + +DL+++ITGE Sbjct: 109 TELIGIIGRALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGE 168 Query: 224 TGVGKELVAQSIHRHSMRSGKPMISLNCAALPETLVESELFGHVRGAFSGAVNERRGKFE 283 +G GKELVA+++H + R P +++N AA+P L+ESELFGH +GAF+GA G+FE Sbjct: 169 SGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFE 228 Query: 284 LADGGSLFLDEVGELPLAVQAKLLRVLQSGQLQRVGSDREHRVDVRLIAATNRDLAEEVR 343 A+GG+LFLDE+G++P+ Q +LLRVLQ G+ VG R DVR++AATN+DL + + Sbjct: 229 QAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSIN 288 Query: 344 AGRFRADLYHRLSVYPLRVPPLRERGRDILLLAGYFLEENRPRLGLRSLRLDHEAQAALL 403 G FR DLY+RL+V PLR+PPLR+R DI L +F+++ + GL R D EA + Sbjct: 289 QGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELMK 347 Query: 404 DYRWPGNVRELEHLVGRASLKALGHNPERSRIVTLHRQDLDLPAETPTPPRSVVEPAPAA 463 + WPGNVRELE+LV R + R I R ++ RS A Sbjct: 348 AHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQA 407 Query: 464 PTTGHS---------------LRAATDAYQRRLIQDCLARHQGSWASAARELGLDRANLA 508 + LI L +G+ AA LGL+R L Sbjct: 408 VEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLR 467 Query: 509 RLARRLQLR 517 + R L + Sbjct: 468 KKIRELGVS 476
>THERMOLYSIN#Thermolysin metalloprotease (M4) family signature. Length = 544 Score = 27.3 bits (60), Expect = 0.010 Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 6/83 (7%) Query: 21 QARDLGPDEALKLRDAGTIKSFEELNKNAIAKHPGSSVHDTELE----EEYGRYIYQVEL 76 R L + A+ ++ A I + ++ + T L EE R Y+V + Sbjct: 128 DKRTLKTEAAISIQQAEMIAKQDVADRVTKERPAAEEGKPTRLVIYPDEETPRLAYEVNV 187 Query: 77 R--DPQGVKWDLELDAATGAVLK 97 R P W +DAA G VL Sbjct: 188 RFLTPVPGNWIYMIDAADGKVLN 210
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 77.6 bits (191), Expect = 9e-19 Identities = 31/117 (26%), Positives = 54/117 (46%) Query: 2 RLLLVEDHVPLADELMASLTRQGYAVDWLADGRDAAVQGASEPYDLIILDLGLPGRPGLE 61 +L+ +D + L +L+R GY V ++ A+ DL++ D+ +P + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILQEWRGLGLATPVLILTARGSWAERIDGLKAGADDYLTKPFHPEELALRIQALLRR 118 +L + PVL+++A+ ++ I + GA DYL KPF EL I L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF06580#Sensor histidine kinase Length = 349 Score = 38.7 bits (90), Expect = 3e-05 Identities = 43/263 (16%), Positives = 87/263 (33%), Gaps = 71/263 (26%) Query: 187 RLQIAQLQQGQRSQLDNQAPEELEPLVEQIN-HLLAHTEETLKRSRNALGNLGHALKTPL 245 + A++ Q + + + +A +L L QIN H + + + L + A + Sbjct: 143 NYKQAEIDQWKMASMAQEA--QLMALKAQINPHFMFNALNNI--RALILEDPTKARE--- 195 Query: 246 AVLVSLAE--REEMARQPELQQVLREQLEQIQQRLGRELGKARLVGEALPGAHFDCAEEL 303 +L SL+E R + Q L ++L + L +L + Sbjct: 196 -MLTSLSELMRYSLRYSNARQVSLADELTVVDSYL--QLASIQ----------------- 235 Query: 304 PSLCDTLRLIHGPHLQVSWSAPPGL---RLPWDREDLLEMLGNLLDNACKWA------DS 354 LQ P + ++P +L + L++N K Sbjct: 236 ----------FEDRLQFENQINPAIMDVQVP----PML--VQTLVENGIKHGIAQLPQGG 279 Query: 355 EVRLTVAQGEGMVRLKVDDDGPGILPDQRQAVLERGTRLDEQVSGHGLGLGIARD-IAEA 413 ++ L + G V L+V++ G L + ++ G GL R+ + Sbjct: 280 KILLKGTKDNGTVTLEVENTGSLALKNTKE--------------STGTGLQNVRERLQML 325 Query: 414 CGGRLSLE-DSPLGGLRVSIELP 435 G ++ G + + +P Sbjct: 326 YGTEAQIKLSEKQGKVNAMVLIP 348
>FLAGELLIN#Flagellin signature. Length = 507 Score = 30.0 bits (67), Expect = 0.041 Identities = 17/98 (17%), Positives = 39/98 (39%), Gaps = 3/98 (3%) Query: 438 DVKVSVRDARSTADQSAAISSQTSAGMQQQFREIDQVATASHEMTATAQDVARSAAQAAD 497 K+S +A + + I+ + + +A + + TA V+ + A Sbjct: 352 SAKLSDLEANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAA 411 Query: 498 AARGADQATRDGLALIDRTTQSIDSLAANLTSAMGQVE 535 AA+ + LA ID +D++ ++L + + + Sbjct: 412 AAKKSTANP---LASIDSALSKVDAVRSSLGAIQNRFD 446
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 64.3 bits (156), Expect = 8e-15 Identities = 33/140 (23%), Positives = 55/140 (39%), Gaps = 9/140 (6%) Query: 6 RTPRSDGESTRARILEVAGRLFAQHGYANTASKAICEEAGADLAAINYHFGSRDALYKAV 65 R + + + TR IL+VA RLF+Q G ++T+ I + AG AI +HF + L+ + Sbjct: 3 RKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEI 62 Query: 66 LVEGHKQFVSLHDLRELADSALPPETKLERFINAIVSRLLDDRSWQSKVCAREILAPTAH 125 L EL A P L ++ L + + + EI+ Sbjct: 63 WELSESNIGEL----ELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEII----- 113 Query: 126 FASLIREEVMPKFEALERII 145 F M + +R + Sbjct: 114 FHKCEFVGEMAVVQQAQRNL 133
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 63.3 bits (154), Expect = 3e-13 Identities = 47/296 (15%), Positives = 100/296 (33%), Gaps = 38/296 (12%) Query: 45 SLAFENSERIVALHAEEGDKVRAGQVLAELDTRTLRLRIETARARIGVQEQVLLRLR--- 101 +++ E R+ +L E+ + + EL+ R T ARI E + + Sbjct: 178 NVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRL 237 Query: 102 NGTRPQEVDQSRARLQAAQAEAELARLELVRLQRIAGGTDGKGVSRQSLDAAAARLKVAR 161 + Q+ A+ + E + + + +A ++ Sbjct: 238 DDFSSLLHKQAIAKHAVLEQENKYVEAV----NELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 162 AEVENQRKAWQLADIGPRDEDIAQAQAELEVARADLRLLEHYLSQAQLKAPRDATVRT-R 220 +N+ L + ++I EL + ++AP V+ + Sbjct: 294 QLFKNE----ILDKLRQTTDNIGLLTLELAKNEERQQASV-------IRAPVSVKVQQLK 342 Query: 221 LLEPGDMASPSRPVFALALTD-PKWVRAYVNERQLGRVHPGQKARVVTDSVPER---PVD 276 + G + + + + + D V A V + +G ++ GQ A + ++ P + Sbjct: 343 VHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLV 402 Query: 277 GRVGYISSVAEFTPKTVETEDLRTSLVYEIRVLLDDPE-------DRLRLGMPATV 325 G+V I+ A ED R LV+ + + +++ L GM T Sbjct: 403 GKVKNINLDA--------IEDQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTA 450
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 39.9 bits (93), Expect = 9e-06 Identities = 39/175 (22%), Positives = 77/175 (44%), Gaps = 13/175 (7%) Query: 205 AREWERGTLESLFVTPVRSAEILLAKIIPYFLVGLL-GLSMCLVSARLLFRVPIQGSLVL 263 R + T E++ T +R +I+L ++ L G + +V+A L + Q +L Sbjct: 92 GRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGY---TQWLSLL 148 Query: 264 LLFSSMLY---LFVTLGIGLLISARTRNQFLASQVAILSSFLPALMLSGFLFDLRNVPTF 320 + F +LG+ + A + + F+ Q +++ P L LSG +F + +P Sbjct: 149 YALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVIT---PILFLSGAVFPVDQLPIV 205 Query: 321 IRLVGSILPATYFMELVKTLFLAGDNWHLALKNLLILAGYAV--FLLNAARLCTR 373 + LP ++ ++L++ + L + ++ L Y V F L+ A L R Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPVVDVCQ-HVGALCIYIVIPFFLSTALLRRR 259
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 59.9 bits (145), Expect = 2e-12 Identities = 43/192 (22%), Positives = 81/192 (42%), Gaps = 3/192 (1%) Query: 182 GLIAALSMI-QTLMLAALSVAREREQGTFDQLLVTPLTPLEILIGKAVPSVLIGLLQSTL 240 G++A +M T + R Q T++ +L T L +I++G+ + L Sbjct: 72 GMVATSAMTAATFETIYAAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAG 131 Query: 241 ILAIGLFWFRIPMAGSLLDLYLGLLVFTTACVGIGLSVSALSANMQQAMVYTFVIMMPLI 300 I + SLL + + A +G+ V+AL+ + + Y +++ P++ Sbjct: 132 IGVVAAALGYTQWL-SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPIL 190 Query: 301 LLSGLITPIHSMPETLQILTYADPLRFAIDLVRRVYLEGASLADISGNFIPMLSVAAVTL 360 LSG + P+ +P Q PL +IDL+R + L D+ + + + Sbjct: 191 FLSGAVFPVDQLPIVFQTAARFLPLSHSIDLIRPIMLGHPV-VDVCQHVGALCIYIVIPF 249 Query: 361 PLAAWLFRNRLV 372 L+ L R RL+ Sbjct: 250 FLSTALLRRRLL 261
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 32.8 bits (74), Expect = 0.002 Identities = 31/103 (30%), Positives = 50/103 (48%), Gaps = 9/103 (8%) Query: 7 LALSILTTIGATAADSAWAAQTSVHLYNW------YDFIAPETPKAFQKETGTRVVLDTF 60 LALS LTT+ +A SA A L W Y+ +A E K F+K+TG +V ++ Sbjct: 10 LALSALTTMMFSA--SALAKIEEGKLVIWINGDKGYNGLA-EVGKKFEKDTGIKVTVEHP 66 Query: 61 DSAETAQGKLMVGRSGYDVVVITSNILPGLIKAGVLQELDRDR 103 D E ++ G D++ + G ++G+L E+ D+ Sbjct: 67 DKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLLAEITPDK 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 43.3 bits (102), Expect = 3e-07 Identities = 31/158 (19%), Positives = 60/158 (37%), Gaps = 7/158 (4%) Query: 9 ARVIVADDYPLFRDGLRRVVRRYLPQAAVSEAGSFDEVLRLASSVSPEPPVLFVLDLLLP 68 A ++VADD R L + + R V + + R ++ L V D+++P Sbjct: 4 ATILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRW---IAAGDGDLVVTDVVMP 58 Query: 69 GFAASQSIERLRRAYRHSAIVIVSMLDDPRLVDEVLAAGADGYLGKSLEAGEIGTALQTL 128 A + R+++A ++++S + + GA YL K + E+ + Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 129 GSGEPVVRLRGGSSAGSRQRALLDALTPRQQAVLRLIA 166 EP R L+ + Q + R++A Sbjct: 119 -LAEPKRRPSKLEDDSQDGMPLV-GRSAAMQEIYRVLA 154
>ICENUCLEATIN#Ice nucleation protein signature. Length = 1258 Score = 38.2 bits (88), Expect = 1e-04 Identities = 35/172 (20%), Positives = 66/172 (38%), Gaps = 7/172 (4%) Query: 495 STASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTV----TIQTGSDSLDVKDTRTVTV 550 ST + G++ LT T+T +E + T T ++ G S ++ Sbjct: 838 STQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTAGYNSILT 897 Query: 551 GADQTHSTGGNYSHKVSGNFELTVDGNLTIKVSGTLALQSGG---SLTLKSDADLAAQAG 607 + T S +G + G + ++G + Q+ +L + A+ Sbjct: 898 AGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQ 957 Query: 608 TSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTVDGGGMLT 659 +SLT+ G++ +SL G++ T +LT G+ QT + LT Sbjct: 958 SSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLT 1009 Score = 37.8 bits (87), Expect = 1e-04 Identities = 50/187 (26%), Positives = 73/187 (39%), Gaps = 13/187 (6%) Query: 483 AQKDLNVNVLNDSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDV 542 AQK ++ ST + G D +L T+T + T T G T T Q GSD L Sbjct: 378 AQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAG-EESTQTAGYGS-TQTAQKGSD-LTA 434 Query: 543 KDTRTVTVGADQTHSTGGNYSHKVSGNFELTVD--GNLTIKVSGTLALQSGGSLTLKSDA 600 T T G D + G + + LT T + L G + T ++ Sbjct: 435 GYGSTGTAGDDSSLIAGYGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTSTAGYES 494 Query: 601 DLAAQAGT--------SLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTV 652 L A G+ +LT+ G++ T Q + L G++ T A SL G+ QT Sbjct: 495 SLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANSSLIAGYGSTQTA 554 Query: 653 DGGGMLT 659 +LT Sbjct: 555 SYNSVLT 561 Score = 37.0 bits (85), Expect = 3e-04 Identities = 53/181 (29%), Positives = 77/181 (42%), Gaps = 19/181 (10%) Query: 483 AQKDLNVNVLNDSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDV 542 AQK ++ ST + G D +L T+T E + T T G T T Q GSD L Sbjct: 282 AQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGE-ESTQTAGYGS-TQTAQKGSD-LTA 338 Query: 543 KDTRTVTVGADQTHSTGGNYSHKVSGNFELTVDGNLTIKVSGTLALQSGGSLTL------ 596 T T G D + G S + +G D +LT T Q G LT Sbjct: 339 GYGSTGTAGDDSS-LIAGYGSTQTAGE-----DSSLTAGYGSTQTAQKGSDLTAGYGSTG 392 Query: 597 --KSDADLAAQAGTSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTVDG 654 +D+ L A G++ T+ ++ T G++ T + G+ LT AG T AG + ++ Sbjct: 393 TAGADSSLIAGYGSTQTAGEESTQTAGYGSTQTAQKGSDLT--AGYGSTGTAGDDSSLIA 450 Query: 655 G 655 G Sbjct: 451 G 451 Score = 35.9 bits (82), Expect = 7e-04 Identities = 45/184 (24%), Positives = 79/184 (42%), Gaps = 7/184 (3%) Query: 483 AQKDLNVNVLNDSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDV 542 AQ++ ++ ST++ G+D +L T+T G ++ T T Q SD L Sbjct: 858 AQENSDLTTGYGSTSTAGYDSSLIAGYGSTQTA--GYNSILTAGYGSTQTAQENSD-LTT 914 Query: 543 KDTRTVTVGADQTHSTGGNYSHKVSGNFELTV--DGNLTIKVSGTLALQSGGSLTLKSDA 600 T T G + + G + S L + T + +L G + D+ Sbjct: 915 GYGSTSTAGYESSLIAGYGSTQTASFKSTLMAGYGSSQTAREQSSLTAGYGSTSMAGYDS 974 Query: 601 DLAAQAGTSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTVDGGGMLTL 660 L A G++ T+ ++LT G++ T + ++LT AG T AGA+ ++ G +L Sbjct: 975 SLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLT--AGYGSTATAGADSSLIAGYGSSL 1032 Query: 661 KGGL 664 G+ Sbjct: 1033 TSGI 1036 Score = 35.5 bits (81), Expect = 8e-04 Identities = 48/187 (25%), Positives = 74/187 (39%), Gaps = 13/187 (6%) Query: 483 AQKDLNVNVLNDSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDV 542 A++ ++ ST + G D ++ T+T ++T G T T + S L Sbjct: 570 AREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTAS-YHSSLTAGYGS-TQTAREQSV-LTT 626 Query: 543 KDTRTVTVGADQTHSTGGNYSHKVSGNFELTVD--GNLTIKVSGTLALQSGGSLTLKSDA 600 T T GAD + G + N LT T + L G + T +D+ Sbjct: 627 GYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTAGYGSTSTAGADS 686 Query: 601 DLAAQAGT--------SLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTV 652 L A G+ LT+ G++ T Q G+ LT+ G++ T A SL G+ QT Sbjct: 687 SLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLTSGYGSTSTAGADSSLIAGYGSTQTA 746 Query: 653 DGGGMLT 659 LT Sbjct: 747 SYHSSLT 753 Score = 35.1 bits (80), Expect = 0.001 Identities = 49/187 (26%), Positives = 75/187 (40%), Gaps = 13/187 (6%) Query: 483 AQKDLNVNVLNDSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDV 542 AQK ++ ST + G D +L T+T E D ++T G T T Q GSD L Sbjct: 426 AQKGSDLTAGYGSTGTAGDDSSLIAGYGSTQTAGE-DSSLTAGYGS-TQTAQKGSD-LTA 482 Query: 543 KDTRTVTVGADQTHSTGGNYSHKVSGNFELTVD--GNLTIKVSGTLALQSGGSLTLKSDA 600 T T G + + G + LT T + L G + T +++ Sbjct: 483 GYGSTSTAGYESSLIAGYGSTQTAGYGSTLTAGYGSTQTAQNESDLITGYGSTSTAGANS 542 Query: 601 DLAAQAGT--------SLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTV 652 L A G+ LT+ G++ T + G+ LT G++ T + S+ G+ QT Sbjct: 543 SLIAGYGSTQTASYNSVLTAGYGSTQTAREGSDLTAGYGSTGTAGSDSSIIAGYGSTQTA 602 Query: 653 DGGGMLT 659 LT Sbjct: 603 SYHSSLT 609 Score = 34.7 bits (79), Expect = 0.001 Identities = 41/175 (23%), Positives = 62/175 (35%), Gaps = 13/175 (7%) Query: 495 STASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDVKDTRTVTVGADQ 554 ST + ++ LT T+T +EG + L G + S+ T T Sbjct: 550 STQTASYNSVLTAGYGSTQTAREGSD---LTAGYGSTGTAGSDSSIIAGYGSTQTASYHS 606 Query: 555 THSTGGNYSHKVSGNFELTV----------DGNLTIKVSGTLALQSGGSLTLKSDADLAA 604 + + G + LT D +L T LT + A Sbjct: 607 SLTAGYGSTQTAREQSVLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTA 666 Query: 605 QAGTSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTVDGGGMLT 659 Q G+ LT+ G++ T A +SL G++ T LT G+ QT G LT Sbjct: 667 QEGSDLTAGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTAQEGSDLT 721 Score = 34.7 bits (79), Expect = 0.001 Identities = 42/164 (25%), Positives = 68/164 (41%), Gaps = 5/164 (3%) Query: 483 AQKDLNVNVLNDSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDV 542 AQ++ ++ ST++ G++ +L T+T ++ TL G + SL Sbjct: 906 AQENSDLTTGYGSTSTAGYESSLIAGYGSTQTA--SFKS-TLMAGYGSSQTAREQSSLTA 962 Query: 543 KDTRTVTVGADQTHSTGGNYSHKVSGNFELTVD--GNLTIKVSGTLALQSGGSLTLKSDA 600 T G D + G + LT T + S TL G + T +D+ Sbjct: 963 GYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEHSSTLTAGYGSTATAGADS 1022 Query: 601 DLAAQAGTSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTN 644 L A G+SLTS + LT G++L + + LT G SL + Sbjct: 1023 SLIAGYGSSLTSGIRSFLTAGYGSTLISGLRSVLTAGYGSSLIS 1066 Score = 32.4 bits (73), Expect = 0.007 Identities = 43/182 (23%), Positives = 58/182 (31%), Gaps = 13/182 (7%) Query: 491 VLNDSTASIGHDETLTVQNARTRT---VKEGDETVTLEKGKRTVTIQTGSDSLDVKDTRT 547 V +D A+I T Q T G L G + S +L T Sbjct: 140 VTDDIDATIESGSTQPTQTIEIATYGSTLSGTHQSQLIAGYGSTETAGDSSTLIAGYGST 199 Query: 548 VTVGADQTHSTGGNYSHKVSGNFELT----------VDGNLTIKVSGTLALQSGGSLTLK 597 T GAD T G + +LT T SL Sbjct: 200 GTAGADSTLVAGYGSTQTAGEESSQMAGYGSTQTGMKGSDLTAGYGSTGTAGDDSSLIAG 259 Query: 598 SDADLAAQAGTSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTVDGGGM 657 + A +SLT+ G++ T Q G+ LT G++ T A SL G+ QT Sbjct: 260 YGSTQTAGEDSSLTAGYGSTQTAQKGSDLTAGYGSTGTAGADSSLIAGYGSTQTAGEEST 319 Query: 658 LT 659 T Sbjct: 320 QT 321 Score = 31.6 bits (71), Expect = 0.012 Identities = 36/162 (22%), Positives = 68/162 (41%), Gaps = 7/162 (4%) Query: 494 DSTASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTV----TIQTGSDSLDVKDTRTVT 549 ST + G++ LT T+T +E + T T ++ G S ++ Sbjct: 885 GSTQTAGYNSILTAGYGSTQTAQENSDLTTGYGSTSTAGYESSLIAGYGSTQTASFKSTL 944 Query: 550 VGADQTHSTGGNYSHKVSGNFELTVDGNLTIKVSGTLALQSGG---SLTLKSDADLAAQA 606 + + T S +G ++ G + ++G + Q+ G +LT + A+ Sbjct: 945 MAGYGSSQTAREQSSLTAGYGSTSMAGYDSSLIAGYGSTQTAGYQSTLTAGYGSTQTAEH 1004 Query: 607 GTSLTSKAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGA 648 ++LT+ G++ T A +SL G+SLT+ LT G+ Sbjct: 1005 SSTLTAGYGSTATAGADSSLIAGYGSSLTSGIRSFLTAGYGS 1046 Score = 30.5 bits (68), Expect = 0.027 Identities = 37/163 (22%), Positives = 59/163 (36%), Gaps = 7/163 (4%) Query: 495 STASIGHDETLTVQNARTRTVKEGDETVTLEKGKRTVTIQTGSDSLDVKDTRTVTVGADQ 554 ST + + +LT T+T +E T G + + SL T T G Sbjct: 742 STQTASYHSSLTAGYGSTQTAREQSVLTT---GYGSTSTAGADSSLIAGYGSTQTAGYHS 798 Query: 555 THSTGGNYSHKVSGNFELTV--DGNLTIKVSGTLALQSGGSLTLKSDADLAAQAGTSLTS 612 + G + +LT T +L G + T ++ L A G++ T+ Sbjct: 799 ILTAGYGSTQTAQERSDLTTGYGSTSTAGADSSLIAGYGSTQTAGYNSILTAGYGSTQTA 858 Query: 613 KAGTSLTNQAGTSLTNKAGTSLTNDAGVSLTNKAGAEQTVDGG 655 + + LT G T+ AG + AG T AG + G Sbjct: 859 QENSDLT--TGYGSTSTAGYDSSLIAGYGSTQTAGYNSILTAG 899
>BONTOXILYSIN#Bontoxilysin signature. Length = 1196 Score = 29.1 bits (65), Expect = 0.034 Identities = 7/21 (33%), Positives = 11/21 (52%) Query: 250 PAIGLAHELLHAYYSCRGAQP 270 PA+ L L+ + Y G +P Sbjct: 218 PAMELTKCLIKSLYFLYGIKP 238
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.8 bits (67), Expect = 0.050 Identities = 37/168 (22%), Positives = 62/168 (36%), Gaps = 22/168 (13%) Query: 575 RSLAQRMGQRVMGQEAALGAIAQRIQAYRAGLSDPAKPVGVFLLSGPTGVGKTETAYALA 634 + G ++G+ AA+ I + + R +D + +++G +G GK A AL Sbjct: 129 LEDDSQDGMPLVGRSAAMQEIYRVLA--RLMQTD--LTL---MITGESGTGKELVARALH 181 Query: 635 DALYGGERNLISINLSEYQEAHTVSQL----KGAPPGYVGYGSGGVLTEAVRRKPYSVVL 690 D ++IN++ S+L KGA G +G + + Sbjct: 182 DYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTG-----RFEQAEGGTLF 236 Query: 691 LDEIEKAHPDVLEAFYNVFDKGVME---DGTGLVVDFRNTVILATSNV 735 LDEI D V +G T + D R I+A +N Sbjct: 237 LDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATNK 281
>SECBCHAPRONE#Bacterial protein-transport SecB chaperone protein signature. Length = 170 Score = 26.4 bits (58), Expect = 0.025 Identities = 8/30 (26%), Positives = 15/30 (50%) Query: 19 EGGFDFARIHPIDFFAIFPSEREARQAAGQ 48 G F + P++F A+F + ++ A Q Sbjct: 131 RGTFPALNLSPVNFDALFMDYLQRQEQAEQ 160
>TYPE3IMPPROT#Type III secretion system inner membrane P protein family signature. Length = 224 Score = 244 bits (624), Expect = 2e-84 Identities = 91/217 (41%), Positives = 141/217 (64%), Gaps = 7/217 (3%) Query: 6 DELGLILGLALLALVPLIAVMATSFIKMTVVFSLLRNALGVQQIPPNMAMYGLAIILSLY 65 +++ LI LA L+P I T F+K ++VF ++RNALG+QQIP NM + G+A++LS++ Sbjct: 3 NDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNGVALLLSMF 62 Query: 66 VMAPVGFATRDYLRNHDVSLSDSASVERFLDEGMAPYRNFLKRQIQEREHTFFMESTRQV 125 VM P+ Y + DV+ +D +S+ + +DEG+ YR++L + FF + + Sbjct: 63 VMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKR 122 Query: 126 WPSEYAERLDPD-------SLLILLPAFTVSELTRAFEIGFLIYLPFIAIDLIISNILLA 178 E E + D S+ LLPA+ +SE+ AF+IGF +YLPF+ +DL++S++LLA Sbjct: 123 QYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVLLA 182 Query: 179 MGMMMVSPMTISLPFKLLLFVLLDGWARLTHGLVISY 215 +GMMM+SP+TIS P KL+LFV LDGW L+ GL++ Y Sbjct: 183 LGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQY 219
>TYPE3IMQPROT#Type III secretion system inner membrane Q protein family signature. Length = 86 Score = 68.3 bits (167), Expect = 4e-19 Identities = 35/78 (44%), Positives = 48/78 (61%) Query: 5 DILHFTNQTLWLVLVLSLPPVLVAALIGTLVSLVQALTQIQEQTLGFVAKLVAVVVVLFA 64 D++ N+ L+LVL+LS P +VA +IG LV L Q +TQ+QEQTL F KL+ V + LF Sbjct: 3 DLVFAGNKALYLVLILSGWPTIVATIIGLLVGLFQTVTQLQEQTLPFGIKLLGVCLCLFL 62 Query: 65 TSGWLGGELYRFAEMTLL 82 SGW G L + + Sbjct: 63 LSGWYGEVLLSYGRQVIF 80
>TYPE3IMRPROT#Type III secretion system inner membrane R protein family signature. Length = 261 Score = 142 bits (360), Expect = 1e-43 Identities = 47/245 (19%), Positives = 100/245 (40%), Gaps = 4/245 (1%) Query: 9 LLLTYSLLLPRIISCFVVLPVLAKQTLGGGLVRNGVACSLALFAYPIVAGSLPPALDALD 68 L Y L R+++ P+L+++++ V+ G+A + P + + P Sbjct: 12 WLNLYFWPLLRVLALISTAPILSERSVPK-RVKLGLAMMITFAIAPSLPANDVPVFSFFA 70 Query: 69 IALLIGKEVLLGLLIGFVATIPFWAMEATGFIIDNQRGAALASTFNPSLGSQTSPTGLLL 128 + L + +++L+G+ +GF F A+ G II Q G + A+ +P+ ++ Sbjct: 71 LWLAV-QQILIGIALGFTMQFAFAAVRTAGEIIGLQMGLSFATFVDPASHLNMPVLARIM 129 Query: 129 TQTLITLFFSGGAFLALVGSLFRSYASWPVSSFFPQLGSQWVAFFYAQFSQMLMLCALFA 188 + LF + L L+ L ++ + P+ S S + + + A Sbjct: 130 DMLALLLFLTFNGHLWLISLLVDTFHTLPIGGEPL--NSNAFLALTKAGSLIFLNGLMLA 187 Query: 189 APLLIAMFLAEFGLALVSRFAPSLNVFILAMPIKSLVASLLLVLYLGILMEHAYDALLLA 248 PL+ + L L++R AP L++F++ P+ V L+ + ++ Sbjct: 188 LPLITLLLTLNLALGLLNRMAPQLSIFVIGFPLTLTVGISLMAALMPLIAPFCEHLFSEI 247 Query: 249 VDPLR 253 + L Sbjct: 248 FNLLA 252
>TYPE3IMSPROT#Type III secretion system inner membrane S protein family signature. Length = 354 Score = 422 bits (1087), Expect = e-150 Identities = 232/349 (66%), Positives = 294/349 (84%) Query: 1 MSAEKTEQPTAKKLRDARRQGQVVKSKEIVSSALILSLVALLMGFSDYYLEHLGKLLLLP 60 MS EKTEQPT KK+RDAR++GQV KSKE+VS+ALI++L A+LMG SDYY EH KL+L+P Sbjct: 1 MSGEKTEQPTPKKIRDARKKGQVAKSKEVVSTALIVALSAMLMGLSDYYFEHFSKLMLIP 60 Query: 61 AEYIDLPFRQALETILENLLQELLYLLAPVLLVAALVVVLSHVGQYGFLLSLDSVKPDLK 120 AE LPF QAL +++N+L E YL P+L VAAL+ + SHV QYGFL+S +++KPD+K Sbjct: 61 AEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAIASHVVQYGFLISGEAIKPDIK 120 Query: 121 KINPVEGAKKIFSIRSLVEFLKSTLKVALLSLLVWLTLQGNLASLLRIPACGLDCVAPVS 180 KINP+EGAK+IFSI+SLVEFLKS LKV LLS+L+W+ ++GNL +LL++P CG++C+ P+ Sbjct: 121 KINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIWIIIKGNLVTLLQLPTCGIECITPLL 180 Query: 181 GLMLRQLMLVCAVGFLAIAVADYAFERHQHYKQLRMSKDEVKREYKEMEGSPEIKSKRRQ 240 G +LRQLM++C VGF+ I++ADYAFE +Q+ K+L+MSKDE+KREYKEMEGSPEIKSKRRQ Sbjct: 181 GQILRQLMVICTVGFVVISIADYAFEYYQYIKELKMSKDEIKREYKEMEGSPEIKSKRRQ 240 Query: 241 FHQELQSSNLRADVRRSSVIVANPTHVAIGIRYRRGETPLPLVTLKHTDALALRVRRIAE 300 FHQE+QS N+R +V+RSSV+VANPTH+AIGI Y+RGETPLPLVT K+TDA VR+IAE Sbjct: 241 FHQEIQSRNMRENVKRSSVVVANPTHIAIGILYKRGETPLPLVTFKYTDAQVQTVRKIAE 300 Query: 301 EEGIPVLQRIPLARALLRDGNVDQYIPADLIQATAEVLRWLESQQTDTP 349 EEG+P+LQRIPLARAL D VD YIPA+ I+ATAEVLRWLE Q + Sbjct: 301 EEGVPILQRIPLARALYWDALVDHYIPAEQIEATAEVLRWLERQNIEKQ 349
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 69.6 bits (170), Expect = 1e-15 Identities = 34/125 (27%), Positives = 52/125 (41%), Gaps = 16/125 (12%) Query: 128 EITLNSSLLFPSGDALPNDAAFDIVEKVAKILAPYKNP---IHVEGFTDDVPIHSPRYPT 184 TL S +LF A ++++ L+ + V G+TD I S Y Sbjct: 214 HFTLKSDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDR--IGSDAY-- 269 Query: 185 NWELSAARAASIVRLLGNDGVEPSRMAAVGYGEFQPVADNASAEGR---------AKNRR 235 N LS RA S+V L + G+ +++A G GE PV N + A +RR Sbjct: 270 NQGLSERRAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRR 329 Query: 236 VVLVI 240 V + + Sbjct: 330 VEIEV 334
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.5 bits (144), Expect = 8e-12 Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 6/142 (4%) Query: 2 AVKVLVVDDSGFFRRRVSEILSADGQIQVVGTATNGREAIEQALALRPDVITMDYEMPLM 61 +LV DD R +++ LS G +N A D++ D MP Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVR--ITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 62 DGITAVRNIMQRCP-TPVLMFSSLTHEGARVTLDALDAGAVDYLPKNFEDISRNPDKVRQ 120 + + I + P PVL+ S+ + A + GA DYLPK F D++ + + Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAI--KASEKGAYDYLPKPF-DLTELIGIIGR 117 Query: 121 LLCEKVLTIARSNRRSISLPPL 142 L E ++ S PL Sbjct: 118 ALAEPKRRPSKLEDDSQDGMPL 139
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 7e-06 Identities = 13/69 (18%), Positives = 30/69 (43%), Gaps = 10/69 (14%) Query: 462 ETDLDKNLVEALADPLV--HLVRNAVDHGIESPEEREAAGKPRVGQVVLSAEQEGDHILL 519 E ++ +++ P++ LV N + HGI P+ G+++L ++ + L Sbjct: 243 ENQINPAIMDVQVPPMLVQTLVENGIKHGIA--------QLPQGGKILLKGTKDNGTVTL 294 Query: 520 MITDDGKGM 528 + + G Sbjct: 295 EVENTGSLA 303
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 89.9 bits (223), Expect = 2e-24 Identities = 32/120 (26%), Positives = 55/120 (45%), Gaps = 3/120 (2%) Query: 2 KILIVDDFSTMRRIIKNLLRDLGFTNTAEADDGTTALPMLHSGNFDFLVTDWNMPGMTGI 61 IL+ DD + +R ++ L G+ + T + +G+ D +VTD MP Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRI-TSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 DLLRAVRADERLKHLPVLMVTAEAKRDQIIEAAQAGVNGYVVKPFTAQVLKEKIEKIFER 121 DLL ++ + LPVL+++A+ I+A++ G Y+ KPF L I + Sbjct: 64 DLLPRIK--KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 264 bits (676), Expect = 2e-91 Identities = 140/242 (57%), Positives = 176/242 (72%), Gaps = 3/242 (1%) Query: 11 LAALCLLLLAPWPALAADPTSISAITVTTNGQGQQEYSVSLQILLIMTALSFIPAFVMLM 70 L+ +LL P A + IT G Q +S+ +Q L+ +T+L+FIPA +++M Sbjct: 5 LSVAPVLLWLITPLAFA---QLPGITSQPLPGGGQSWSLPVQTLVFITSLTFIPAILLMM 61 Query: 71 TSFTRIIIVFSILRQALGLQSTPSNQVLVGLALFLTMFVMAPVFDKINSQALQPYLNEQI 130 TSFTRIIIVF +LR ALG S P NQVL+GLALFLT F+M+PV DKI A QP+ E+I Sbjct: 62 TSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMSPVIDKIYVDAYQPFSEEKI 121 Query: 131 PAQEALQKAEVPLKAFMLAQTRTSDLELFVRLSKRTDIGSPEATPLTILVPAFVTSELKT 190 QEAL+K PL+ FML QTR +DL LF RL+ + PEA P+ IL+PA+VTSELKT Sbjct: 122 SMQEALEKGAQPLREFMLRQTREADLGLFARLANTGPLQGPEAVPMRILLPAYVTSELKT 181 Query: 191 AFQIGFMIFIPFLIIDLVVSSVLMAMGMMMLSPLIISLPFKIMLFVLVDGWALIIGTLAG 250 AFQIGF IFIPFLIIDLV++SVLMA+GMMM+ P I+LPFK+MLFVLVDGW L++G+LA Sbjct: 182 AFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIALPFKLMLFVLVDGWQLLVGSLAQ 241 Query: 251 SF 252 SF Sbjct: 242 SF 243
>FLGMOTORFLIN#Flagellar motor switch protein FliN signature. Length = 137 Score = 120 bits (301), Expect = 8e-38 Identities = 62/145 (42%), Positives = 90/145 (62%), Gaps = 24/145 (16%) Query: 13 ALADEWAAALAE-AGDASQDDIDALMAQGGATPVAEPSTPRAPMEEFGASPKAPTISGLE 71 AL D WA AL E ++ DA+ Q G V+ Sbjct: 14 ALDDLWADALNEQKATTTKSAADAVFQQLGGGDVSGAMQ--------------------- 52 Query: 72 GPNLDVILDIPVTISMEVGHTDISIRNLLQLNQGSVIELDRLAGEPLDVLVNGTLIAHGE 131 ++D+I+DIPV +++E+G T ++I+ LL+L QGSV+ LD LAGEPLD+L+NG LIA GE Sbjct: 53 --DIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILINGYLIAQGE 110 Query: 132 VVVVNEKFGIRLTDVISPSERIKKL 156 VVVV +K+G+R+TD+I+PSER+++L Sbjct: 111 VVVVADKYGVRITDIITPSERMRRL 135
>FLGMOTORFLIM#Flagellar motor switch protein FliM signature. Length = 344 Score = 259 bits (664), Expect = 2e-87 Identities = 98/326 (30%), Positives = 167/326 (51%), Gaps = 13/326 (3%) Query: 5 DLLSQDEIDALLHGVDDGLVETEVEATPG-----SVKSYDLTSQDRIVRGRMPTLEMINE 59 ++LSQDEID LL + G + +E + YD D+ + +M TL +++E Sbjct: 3 EVLSQDEIDQLLTAISSG--DASIEDARPISDTRKITLYDFRRPDKFSKEQMRTLSLMHE 60 Query: 60 RFARYTRISMFNLLRRSADVAVGGVQVMKFGEYVHSLYVPTSLNLVKMKPLRGTALFILD 119 FAR T S+ LR V V V + + E++ S+ P++L ++ M PL+G A+ +D Sbjct: 61 TFARLTTTSLSAQLRSMVHVHVASVDQLTYEEFIRSIPTPSTLAVITMDPLKGNAVLEVD 120 Query: 120 AKLVFKLVDNFFGGDGRHAKIEGREFTPTELRVVRMVLEQAFVDLKEAWQAVLEMNFEYV 179 + F ++D FGG G+ AK++ R+ T E V+ V+ + +++E+W V+++ Sbjct: 121 PSITFSIIDRLFGGTGQAAKVQ-RDLTDIENSVMEGVIVRILANVRESWTQVIDLRPRLG 179 Query: 180 NSEVNPAMANIVSPSEVVVVSTFHIELDGGGGDLHITMPYSMIEPIREMLDAGF--QSDH 237 E NP A IV PSE+VV+ T ++ G ++ +PY IEPI L + F S Sbjct: 180 QIETNPQFAQIVPPSEMVVLVTLETKVGEEEGMMNFCIPYITIEPIISKLSSQFWFSSVR 239 Query: 238 DDQDERWIKALREDVLDVQVPLGATVVRRQLKLRDILHMQPGDVIPVE---MPEHMVMRA 294 +++ LR+ + V + + A V +L +RDIL ++ GD+I + + + V+ Sbjct: 240 RSSTTQYMGVLRDKLSTVDMDVVAEVGSLRLSVRDILGLRVGDIIRLHDTHVGDPFVLSI 299 Query: 295 NGVPAFKVKLGAHKGNLALQILEAVE 320 F + G +A QILE +E Sbjct: 300 GNRKKFLCQPGVVGKKIAAQILERIE 325
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 52.1 bits (124), Expect = 2e-09 Identities = 73/302 (24%), Positives = 115/302 (38%), Gaps = 14/302 (4%) Query: 126 LLDENTQATLLPPAVPTASSAPASLTEASSDPTLVKLNGVPAVNMALEQGAQDAAQTAKG 185 + DE + +T L A A +A A + V A AL T K Sbjct: 88 INDEQSTSTPLTTAQTMALAAVADKNTTKDEKADDLNEDVTASLSALFAMLPGFDNTPKV 147 Query: 186 GPAKSADPRQANLGDALAGLTSDSLTKAVDGKALEAQLQQTAEPAVASAASESLLESKAE 245 A S LTS+ LT A A Q P VA A S++ + S Sbjct: 148 TDAPST-VLPTEKPTLFTKLTSEQLTTAQPDDAPGTPAQPLT-PLVAEAQSKAEVISTPS 205 Query: 246 PRGEPFAAKLNGLTQAMAQQALTNRPVNGTVPGQPVAMQQNGWSEAVVDRVMWMSSQNLK 305 P AA +T Q T P + + W +++ + + Q + Sbjct: 206 PVT---AAASPLITPHQTQPLPT-----VAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQ 257 Query: 306 SAEIQLDPAELGRLDVRIHMTADQTQVTFASPNAGVRDALESQMHRLRDMFSQQGMNQLD 365 SAE++L P +LG + + + + +Q Q+ SP+ VR ALE+ + LR ++ G+ Sbjct: 258 SAELRLHPQDLGEVQISLKVDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQ 317 Query: 366 VNVSDQSLARGWQGQQQGEGGSARGRGLAGEASGDEETLAGVSEIRSRPGASAARGLVDY 425 N+S +S + G Q + S R A D++TL ++ G VD Sbjct: 318 SNISGESFS-GQQQAASQQQQSQRTANHEPLAGEDDDTLPVPVSLQ---GRVTGNSGVDI 373 Query: 426 YA 427 +A Sbjct: 374 FA 375
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.035 Identities = 17/93 (18%), Positives = 30/93 (32%), Gaps = 5/93 (5%) Query: 316 EETSLAGEIATTVDFLEVI----FDEAGVGIEVRGEAR-ALVERALFQRAVTNLLYNAAQ 370 + SLA E+ +L++ D ++ V L Q V N + + Sbjct: 214 RQVSLADELTVVDSYLQLASIQFEDRLQFENQINPAIMDVQVPPMLVQTLVENGIKHGIA 273 Query: 371 HTAAGGTLRVGVERRGDEVRVAVSNPGVPIADE 403 GG + + + V + V N G Sbjct: 274 QLPQGGKILLKGTKDNGTVTLEVENTGSLALKN 306
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.0 bits (213), Expect = 1e-21 Identities = 33/129 (25%), Positives = 62/129 (48%), Gaps = 2/129 (1%) Query: 2 RVLIVEDEAKTADYLNRGLSEQGFTVDLADNGIDGRHLALHGEYDVIVLDVMLPGVDGYG 61 +L+ +D+A LN+ LS G+ V + N G+ D++V DV++P + + Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLRALRERR-QTPVIMLTARERVEDRVRGLREGADDYLIKPFSFLELVARL-QALTRRGG 119 +L +++ R PV++++A+ ++ +GA DYL KPF EL+ + +AL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 120 NHESHSQMR 128 Sbjct: 125 RPSKLEDDS 133
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 760 bits (1965), Expect = 0.0 Identities = 290/1040 (27%), Positives = 489/1040 (47%), Gaps = 36/1040 (3%) Query: 7 ISGWCVRHPIATALLTLASLLLGLLAFLRLGVAPLPEADFPTIQINALLPGGSPETMASS 66 ++ + +R PI +L + ++ G LA L+L VA P P + ++A PG +T+ + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 67 VATPLEVQFSAIPGITEMTSSSA-LGTTTLTLQFSLDKSIDVAAQEVQAAINAAAGRLPV 125 V +E + I + M+S+S G+ T+TL F D+A +VQ + A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 126 DMPNLPTWRKVNPADSPIMILRVNSE--MMPLIELSDYAEIILARQLSQVNGVGQIFVVG 183 ++ + S +M+ S+ ++SDY + LS++NGVG + + G Sbjct: 121 EVQQ-QGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG 179 Query: 184 QQRPAIRIQAQPEKLAAYQLTLADLRQSLQSASVNLAKGALYGEGRVS------TLAAND 237 Q A+RI + L Y+LT D+ L+ + +A G L G + ++ A Sbjct: 180 AQY-AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 238 QLFNASDYDDLVV-AYRQGAPVFLKDVARIVSAPEDDYVQAWPNGVPGVALVILRQPGAN 296 + N ++ + + G+ V LKDVAR+ E+ V A NG P L I GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 297 IVDTADAIQAALPRLREMLPATIEVDVLNDRTRTIRSSLHEVELTLLLTIGLVVLVMGLF 356 +DTA AI+A L L+ P ++V D T ++ S+HEV TL I LV LVM LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 357 LRQLSATLIVATVLAVSLSASFAAMYVLGFTLNNLTLVALIIAVGFIVDDAIVVVENIHR 416 L+ + ATLI + V L +FA + G+++N LT+ +++A+G +VDDAIVVVEN+ R Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 417 HL-EAGASKVEAALKGAAEIGFTVISISFSLIAAFIPLLFMGGIVGRLFREFAVSVTVAI 475 + E EA K ++I ++ I+ L A FIP+ F GG G ++R+F++++ A+ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 476 LISVLASLTLAPMLASRFM-PALRHADAPRKGFAEW-------LTGGYERGLRWALGHQR 527 +SVL +L L P L + + P + GF W Y + LG Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 528 LMLVGFAFTVLVAVAGYVGIPKGFFPLQDTAFVFGTSQAAEDISYDDMVAKHRQLAEIIA 587 L+ +A V V ++ +P F P +D Q + + Q+ + Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 588 SDPA--VQSYNHAVGVTGGSQSLANGRFWIVLKDRGERDV---SVGEFIDRLRPQLAKVP 642 + V+S G + Q+ G ++ LK ER+ S I R + +L K+ Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 643 GIMLYLRAAQDINLSSGPSRTQYQYAL---RSSDSTQLALWAQRLTERLKQVPG-LMDVS 698 + I + T + + L L +L Q P L+ V Sbjct: 659 DGFVIPFNMPAI--VELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVR 716 Query: 699 NDLQVGASVTALDIDRVAAARFGLSAEDVSQTLYDAFGQRQVGEYQTEVNQYKVVLELDA 758 + + L++D+ A G+S D++QT+ A G V ++ K+ ++ DA Sbjct: 717 PNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADA 776 Query: 759 RQRGRAESLDWFYLRSPLSGEMVPLSAIAKVAAPRSGPLQINHNGMFPAVNLSFNLAAGV 818 + R E +D Y+RS +GEMVP SA G ++ P++ + A G Sbjct: 777 KFRMLPEDVDKLYVRSA-NGEMVPFSAFTTSH-WVYGSPRLERYNGLPSMEIQGEAAPGT 834 Query: 819 SLGEAVQAVQRAQEEIGMPSTIIGVFQGAAQAFQSSLASQPLLILAALIAVYIILGVLYE 878 S G+A+ ++ + +P+ I + G + + S P L+ + + V++ L LYE Sbjct: 835 SSGDAMALMENLASK--LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYE 892 Query: 879 SFVHPLTILSTLPSAGIGAVFLLWAWGQDFSIMALIGIVLLIGIVKKNGILMVDFAIVAQ 938 S+ P++++ +P +G + + Q + ++G++ IG+ KN IL+V+FA Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLM 952 Query: 939 REQGMSAEQAIYQACLTRFRPIMMTTLAALLGAIPLMIGFGTGSELRQPLGIAVVGGLLV 998 ++G +A A R RPI+MT+LA +LG +PL I G GS + +GI V+GG++ Sbjct: 953 EKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012 Query: 999 SQVLTLFSTPVVYLALERLF 1018 + +L +F PV ++ + R F Sbjct: 1013 ATLLAIFFVPVFFVVIRRCF 1032
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.8 bits (119), Expect = 1e-08 Identities = 28/159 (17%), Positives = 56/159 (35%), Gaps = 36/159 (22%) Query: 56 VEQQVSGIGTVTSLHNV-VIRTQIDGQLTRLLVSEGQMVEAGELLATIDD-------RAV 107 VE + G +T I+ + + ++V EG+ V G++L + Sbjct: 80 VEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKT 139 Query: 108 VAALEQAQASRASNQAQLKS--------------------AEQDLQRYRSLYAER----- 142 ++L QA+ + Q +S +E+++ R SL E+ Sbjct: 140 QSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQ 199 Query: 143 ---AVSRQLLDQQQATVDQLRATLKANDATINAERVRLS 178 LD+++A + A + + E+ RL Sbjct: 200 NQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLD 238 Score = 39.4 bits (92), Expect = 2e-05 Identities = 42/207 (20%), Positives = 78/207 (37%), Gaps = 16/207 (7%) Query: 110 ALEQAQASRASNQAQLKSAEQDLQRYRSLYAERAVSRQLLDQ--QQATVDQLR-ATLKAN 166 A+ + + +L+ + L++ S QL+ Q + +D+LR T Sbjct: 253 AVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIG 312 Query: 167 DAT--INAERVRLSYTRITSPVSGKVGIRNV-DVGNLVRVGDSLGLFSVTQIAPISVVFS 223 T + R + I +PVS KV V G +V ++L + V + + V Sbjct: 313 LLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETL-MVIVPEDDTLEVTAL 371 Query: 224 LQQEQLPQLQALLGGEAAVRAY-SRDGGSALGEGRLLTIDNQIDSSTGTI-RVRASFD-- 279 +Q + + + V A+ G +G+ + + +D D G + V S + Sbjct: 372 VQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIEDQRLGLVFNVIISIEEN 431 Query: 280 -----NRQARLWPGQFVAVSLHTGVRR 301 N+ L G V + TG+R Sbjct: 432 CLSTGNKNIPLSSGMAVTAEIKTGMRS 458
>AUTOINDCRSYN#Autoinducer synthesis protein signature. Length = 216 Score = 153 bits (387), Expect = 5e-49 Identities = 41/177 (23%), Positives = 74/177 (41%), Gaps = 6/177 (3%) Query: 14 KLLGEMHKLRAQVFKERKGWDVSVIDEMEIDGYDALSPYYMLIQEDTPEAQVFGCWRILD 73 GE+ LR + FK+R W V D ME D YD + Y+ +D V R ++ Sbjct: 15 TKSGELFTLRKETFKDRLNWAVQCTDGMEFDQYDNNNTTYLFGIKDN---TVICSLRFIE 71 Query: 74 TTGPYMLKNTFPELLHGKEAPCSPHIWELSRFAINSGQKGSLGFSDCTLEAMRALARYSL 133 T P M+ TF P + E SRF ++ + + ++ + +M L+ + Sbjct: 72 TKYPNMITGTFFPYFKEINIPEGNY-LESSRFFVDKSRAKDILGNEYPISSMLFLSMINY 130 Query: 134 QND--IQTLVTVTTVGVEKMMIRAGLDVSRFGPHLKIGIERAVALRIELNAKTQIAL 188 D + T+ + + ++ R+G + L ER + + ++ + Q AL Sbjct: 131 SKDKGYDGIYTIVSHPMLTILKRSGWGIRVVEQGLSEKEERVYLVFLPVDDENQEAL 187
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 36.7 bits (85), Expect = 5e-04 Identities = 32/195 (16%), Positives = 59/195 (30%), Gaps = 23/195 (11%) Query: 433 RNLLLHPAVQANRVDTRFVESHLETLLAPIPASHPRLRAECPLA--------------ED 478 R L P + + F+ +HLE + P+ PRL A + E Sbjct: 26 RKQLDTPVREK--DENEFLPAHLELIETPVSR-RPRLVAYFIMGFLVIAFILSVLGQVEI 82 Query: 479 AAPA--RVEAPLGSLPLSAPSSGVLVALEVADGERVRAGQRVAILEAMKMEFEVKAPGGG 536 A A ++ S + + ++ + V +GE VR G + L A+ E + Sbjct: 83 VATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLK---- 138 Query: 537 IVRRLAASLGEPLEEGATLLFLEPTEDDDEQAPTEQALDLAHIRADLAEVLERQAALGDE 596 L + E +E + + + P E L + Sbjct: 139 TQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTW 198 Query: 597 RRPQALARRRKTGQR 611 + + +R Sbjct: 199 QNQKYQKELNLDKKR 213
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 59.1 bits (143), Expect = 1e-12 Identities = 34/157 (21%), Positives = 58/157 (36%), Gaps = 5/157 (3%) Query: 3 GRIIVADDHPLFREGMLSILQRLLPEARIEEAGDLAGVLRLAGEGEQPDSLILDLRFPGL 62 I+VADD R + L R + + A + R G D ++ D+ P Sbjct: 4 ATILVADDDAAIRTVLNQALSRA--GYDVRITSNAATLWRWIAAG-DGDLVVTDVVMPDE 60 Query: 63 TRIEMLADLRRRFPRTTLIVVSMVDDPQLIGEVMNAGADGFLGKSIAPEELGQAILAIRA 122 ++L +++ P ++V+S + + GA +L K EL I RA Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG--RA 118 Query: 123 GEVLVRYEPSGLLPLQPSPGLEGLTERQLDVLRLLAQ 159 R Q L G + ++ R+LA+ Sbjct: 119 LAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR 155
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 49.8 bits (119), Expect = 2e-08 Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 9/124 (7%) Query: 416 LTGLRVCLVEDDRNVLRATSALLERWGCTVQ-AETEADGWRTDC----DILVVDYDLGPH 470 +TG + + +DD + + L R G V+ A WR D++V D + P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVM-PD 59 Query: 471 ASGVECIERVRRQRGEAIPALVISGH-DIERIQASVEDTDIALLSKPVRPTELRATL-RA 528 + + + R+++ +P LV+S + E L KP TEL + RA Sbjct: 60 ENAFDLLPRIKK-ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 529 LRER 532 L E Sbjct: 119 LAEP 122
>MPTASEINHBTR#Metalloprotease inhibitor signature. Length = 122 Score = 129 bits (325), Expect = 5e-42 Identities = 40/118 (33%), Positives = 58/118 (49%), Gaps = 9/118 (7%) Query: 12 CLLCGFFSTGI-SMASSLILLSASDLAGQWTLQQDEAPAICHLELRDSEVAEASGYDLGG 70 F S G +MASS ++ S + +AGQ ++ +C +E A A L G Sbjct: 11 VWQVLFVSAGAQAMASSFVVPSTAQMAGQLGIEATG-SGVC---AGPAEQANA----LAG 62 Query: 71 DTACLTRWLPSEPRAWRPTPAGIALLERGGLTLMLLGRQGEGDYRVQKGDGGQLVLRR 128 D AC +WL +P +W PTP GI L+ G + L RQ EG+Y + G + L+R Sbjct: 63 DVACAEQWLGDKPVSWSPTPDGIWLMNAEGTGITHLNRQKEGEYTGRTPSGADVTLQR 120
>CABNDNGRPT#NodO calcium binding signature. Length = 479 Score = 418 bits (1077), Expect = e-145 Identities = 254/480 (52%), Positives = 319/480 (66%), Gaps = 29/480 (6%) Query: 10 GRSDAYTQVDNFLHAYARGGDELVNGHPSYTVDQAAEQILREQASWQKAPGDSVLTLSYS 69 S AY V +FL + RG VNG SY++DQAA QI RE SW G +V S Sbjct: 19 NTSSAYNSVYDFLRYHDRGDGLTVNGKTSYSIDQAAAQITRENVSWN---GTNVFGKSA- 74 Query: 70 FLTKPNDFFNTPWKYVSDIYSLGK----FSAFSAQQQAQAKLSLQSWADVTNIHFVDAGQ 125 N +K++ + S+ F F+A+Q QAKLSLQSW+DV N+ F + Sbjct: 75 ---------NLTFKFLQSVSSIPSGDTGFVKFNAEQIEQAKLSLQSWSDVANLTFTEVTG 125 Query: 126 GDQGDLTFGNFSSSVGG------AAFAFLPDVPDALKGQSWYLINSSYSANVNPANGNYG 179 ++TFGN++ G A+A+ P G SWY N S NP + YG Sbjct: 126 NKSANITFGNYTRDASGNLDYGTQAYAYYPGNYQG-AGSSWYNYNQSN--IRNPGSEEYG 182 Query: 180 RQTLTHEIGHTLGLSHPGDYNAGEGDPTYADATYAEDTRAYSVMSYWEEQNTGQDFKGAY 239 RQT THEIGH LGL+HPG+YNAGEGDP+Y DA YAED+ +S+MSYW E TG D+ G Y Sbjct: 183 RQTFTHEIGHALGLAHPGEYNAGEGDPSYNDAVYAEDSYQFSIMSYWGENETGADYNGHY 242 Query: 240 SSAPLLDDIAAIQKLYGANLTTRTGDTVYGFNSNTERDFYSATSSSSKLVFSVWDAGGND 299 AP++DDIAAIQ+LYGAN+TTRTGD+VYGFNSNT+RDFY+AT SS L+FSVWDAGG D Sbjct: 243 GGAPMIDDIAAIQRLYGANMTTRTGDSVYGFNSNTDRDFYTATDSSKALIFSVWDAGGTD 302 Query: 300 TLDFSGFSQNQKINLNEKALSDVGGLKGNVSIAAGVTVENAIGGSGSDLLIGNDVANVLK 359 T DFSG+S NQ+INLNE + SDVGGLKGNVSIA GVT+ENAIGGSG+D+L+GN N+L+ Sbjct: 303 TFDFSGYSNNQRINLNEGSFSDVGGLKGNVSIAHGVTIENAIGGSGNDILVGNSADNILQ 362 Query: 360 GGAGNDILYGGLGADQLWGGAGADTFVYGDIAESSAAAPDTLRDFVSGQDKIDLSGLDAF 419 GGAGND+LYGG GAD L+GGAG DTFVYG +S+ AA D + DF G DKIDLS AF Sbjct: 363 GGAGNDVLYGGAGADTLYGGAGRDTFVYGSGQDSTVAAYDWIADFQKGIDKIDLS---AF 419 Query: 420 VNGGLVLQYVDAFAGKAGQAILSYDAASKAGSLAIDFSGDAHADFAINLIGQATQADIVV 479 N G + D F GK + +L +DAA+ +L + +G + DF + ++GQA Q+DI+V Sbjct: 420 RNEGQLSFVQDQFTGKGQEVMLQWDAANSITNLWLHEAGHSSVDFLVRIVGQAAQSDIIV 479
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 438 bits (1128), Expect = e-154 Identities = 99/423 (23%), Positives = 181/423 (42%), Gaps = 2/423 (0%) Query: 11 AYARLGWLLVLFGFGGALLWAAFAPLDQGVAVPATVIISGQRKSVQHPLGGVVKHILVRD 70 RL ++ A + + ++ + SG+ K ++ +VK I+V++ Sbjct: 55 RRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKE 114 Query: 71 GQHVEAGEPLIRMEPTQARANVDSLLNRYANARLNQARLQAEYDGRRTLEMPA-GLAEQA 129 G+ V G+ L+++ A A+ + ARL Q R Q ++P L ++ Sbjct: 115 GESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEP 174 Query: 130 PLPTLGERLEL-QRQLLHSRQTALANELSALRANIEGLRAQLEGLRQTEGNQRLQQRLLN 188 + E L L+ + + N+ N++ RA+ + R+ Sbjct: 175 YFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEK 234 Query: 189 SQLSGARDLAEEGYMPRNQLLEQERQLAEVNARLSESSGRFGQIRQSIAEAQMRIAQREE 248 S+L L + + ++ +LEQE + E L + QI I A+ + Sbjct: 235 SRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQ 294 Query: 249 EYRKEVNGQLAETQVNARTLWEELSSARYELRHAEIRAPVSGYVAGLKVFTDGGVIGPGE 308 ++ E+ +L +T N L EL+ + + IRAPVS V LKV T+GGV+ E Sbjct: 295 LFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE 354 Query: 309 LLMYIVPNSDSLEVEGQLAVNLVDRIHSGLPVEMLFTAFNQSKTPRVTGEVTMVSADRLL 368 LM IVP D+LEV + + I+ G + AF ++ + G+V ++ D + Sbjct: 355 TLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIE 414 Query: 369 DEQNKQPYYALRAQVDAAAMGKLKGLQIRPGMAVQVFVRTGERSLLNYLFKPLFDRAHVA 428 D++ + + + + K + + GMAV ++TG RS+++YL PL + + Sbjct: 415 DQRLGLVFNVIISIEENCLSTGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTES 474 Query: 429 LAE 431 L E Sbjct: 475 LRE 477
>ENTSNTHTASED#Enterobactin synthetase component D signature. Length = 234 Score = 88.5 bits (219), Expect = 2e-23 Identities = 62/200 (31%), Positives = 93/200 (46%), Gaps = 12/200 (6%) Query: 15 LDDRWPLPVALPGVQLRSTRFDPALLQPGDFALAGIQPPANILRAVAKRQAEFLAGRLCA 74 L +PLP A G +L FD + + D L + + A KR+AE LAGR+ A Sbjct: 2 LTSHFPLPFA--GHRLHIVDFDASSFREHD--LLWLPHHDRLRSAGRKRKAEHLAGRIAA 57 Query: 75 RAALFALDGRAQTPAVGEDRAPVWPAAISGSITHGDRWAAALVAARGDWRGLGLDVETLL 134 AL + G P +G+ R P+WP + GSI+H A A+++ + +G+D+E ++ Sbjct: 58 VHALREV-GVRTVPGMGDKRQPLWPDGLFGSISHCATTALAVISR----QRIGIDIEKIM 112 Query: 135 EAERARYLHGEILTEGERLRFADDLERRTGLLVTLAFSLKESLFKALYPLVGKRFYFEHA 194 A L I+ ER L L +TLAFS KES++KA + F A Sbjct: 113 SQHTATELAPSIIDSDERQILQASL-LPFPLALTLAFSAKESVYKA-FSDRVTLPGFNSA 170 Query: 195 ELLEWRADGQARLRLLTDLS 214 ++ A L LL + Sbjct: 171 KVTSLTA-THISLHLLPAFA 189
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 30.0 bits (67), Expect = 0.009 Identities = 14/51 (27%), Positives = 18/51 (35%), Gaps = 3/51 (5%) Query: 109 MAEYIVDF--DYLIDCIDSVAAKAALIAWCKRRKIPVITTGGAGGQVDPTQ 157 M Y VD + A L C + IPV+ T G Q +P Sbjct: 38 MQNYFVDAFTAGASPVTELSANIRKLKNQCVQLGIPVVYTAQPGSQ-NPDD 87
>PF05704#Capsular polysaccharide synthesis protein Length = 307 Score = 30.6 bits (69), Expect = 0.024 Identities = 7/32 (21%), Positives = 20/32 (62%), Gaps = 1/32 (3%) Query: 430 YNEPPELLKQTLDALARLDYPDYEVLVIDNNT 461 + P +++Q + ++ + + D++V++ID N Sbjct: 79 IEKAPYIVQQCVASV-KKNSGDFKVIIIDGNN 109
>PF06580#Sensor histidine kinase Length = 349 Score = 41.8 bits (98), Expect = 3e-06 Identities = 21/107 (19%), Positives = 35/107 (32%), Gaps = 25/107 (23%) Query: 345 LQNLLTNALRHA------DRRVRISYRVSLERCRVDVEDDGPGVPEAQWERLFTPFLRLD 398 +Q L+ N ++H ++ + ++VE+ G + E Sbjct: 260 VQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNTKE---------- 309 Query: 399 DSRTRASGGHGLGLSIVR-RIVYWHGGRASIGRSETLGGACFTLAWP 444 G GL VR R+ +G A I SE G + P Sbjct: 310 --------STGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 3e-19 Identities = 37/148 (25%), Positives = 66/148 (44%), Gaps = 3/148 (2%) Query: 7 RILIVEDDRRLAELTREYLEGNGLKVDIEANGALAAARILAERPDLVVLDLMLPGEDGLS 66 IL+ +DD + + + L G V I +N A I A DLVV D+++P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 67 ICRQVR-PQFDGPILMLTARTDDMDEVLGLEMGADDYVCKPVRPRVLLARIRALLRRSEA 125 + +++ + D P+L+++A+ M + E GA DY+ KP L+ I L + Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 126 PEAGAPAADSKRLAFGRLVIDNAMREAW 153 + + + AM+E + Sbjct: 125 RPSKLEDD--SQDGMPLVGRSAAMQEIY 150
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 57.1 bits (138), Expect = 4e-11 Identities = 82/337 (24%), Positives = 125/337 (37%), Gaps = 34/337 (10%) Query: 4 RPRPPLLLVLALLALPQVAETILSPALPALASHWRLDDATSQWT------MALFFVGFAP 57 +P PL+++L+ +AL V ++ P LP L + + AL AP Sbjct: 2 KPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAP 61 Query: 58 GIWLWGWLADRLGRRPALLGGLGLAALATFGAWASTDYSYLLACRLVQGLGLATCSVTVQ 117 + G L+DR GRRP LL L AA+ + L R+V G+ AT +V Sbjct: 62 ---VLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAV-AG 117 Query: 118 ASLRDVLQGPALMSYFVTLGAVLAWSPAVGPLGGQWLADLGGH-PAVFATLAVLLASLAA 176 A + D+ G +F + A + GP+ G + H P A L L Sbjct: 118 AYIADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTG 177 Query: 177 LVV---PAWPETRPLLAGTPEPATLAIFRRVLADRPLQTRALLVAVLNVLVFSFYAAGPF 233 + E RPL P FR + + V + LV AA Sbjct: 178 CFLLPESHKGERRPLRREALNPLAS--FRWARGMTVVAA-LMAVFFIMQLVGQVPAALWV 234 Query: 234 MVGDLPGLGFGW----IGLAIAIAGSLGAL----LNRRLPRTWNSARRVRLGLALAAAGA 285 + G+ F W IG+++A G L +L + + R + LG+ A Sbjct: 235 IFGEDR---FHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGM---IADG 288 Query: 286 TAQTLLAAVGYAEGLYWALPALPIFIGFGVAIPNLLG 322 T LLA + A P + + G+ +P L Sbjct: 289 TGYILLAFATRG---WMAFPIMVLLASGGIGMPALQA 322
>FLGFLIJ#Flagellar FliJ protein signature. Length = 147 Score = 54.4 bits (130), Expect = 2e-12 Identities = 46/134 (34%), Positives = 74/134 (55%) Query: 8 LAPVVDMASKAERDAATQLGRCQQQLLAAQQKLAELERYRNDYQQQWISQGQKGVSGQWL 67 LA + D+A K DAA LG ++ A+++L L Y+N+Y+ S G++ Sbjct: 7 LATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLIDYQNEYRNNLNSDMSAGITSNRW 66 Query: 68 MNYQRFLSQLETAVAQQANSVTWHREAVDKARLNWQERYARLEGLRKLVERYLEEARQAE 127 +NYQ+F+ LE A+ Q + + VD A +W+E+ RL+ + L ER A AE Sbjct: 67 INYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWREKKQRLQAWQTLQERQSTAALLAE 126 Query: 128 DKREQKQLDELAQR 141 ++ +QK++DE AQR Sbjct: 127 NRLDQKKMDEFAQR 140
>FLGFLIH#Flagellar assembly protein FliH signature. Length = 228 Score = 56.7 bits (136), Expect = 1e-11 Identities = 47/202 (23%), Positives = 93/202 (46%), Gaps = 11/202 (5%) Query: 40 VAAPQVPAVAEPAPAPPAVEEVELETVKPPTLEEIEAIRQDAYNEGFATGERDGFHAGQL 99 +A PQ V P +EE E + +++A Q Y G A G + G G Sbjct: 15 LAPPQAEFVPIVEPEETIIEEAEPSLEQQLAQLQMQAHEQ-GYQAGIAEGRQQGHKQGYQ 73 Query: 100 KARQEAEEALKERLQS--------LERLMTQLLEPIAEQDALIEQGMVNLVNHVARQVIQ 151 + + E +S +++L+++ + D++I ++ + ARQVI Sbjct: 74 EGLAQGLEQGLAEAKSQQAPIHARMQQLVSEFQTTLDALDSVIASRLMQMALEAARQVIG 133 Query: 152 RELHMDSSHVRQVLREALKLLPMGAANIRIHVNPQDFERVKAL--RERHEESWRILEDDS 209 + +D+S + + +++ L+ P+ + ++ V+P D +RV + WR+ D + Sbjct: 134 QTPTVDNSALIKQIQQLLQQEPLFSGKPQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPT 193 Query: 210 LLPGGCRIETEHSRIDATIETR 231 L PGGC++ + +DA++ TR Sbjct: 194 LHPGGCKVSADEGDLDASVATR 215
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 305 bits (784), Expect = e-105 Identities = 109/330 (33%), Positives = 204/330 (61%) Query: 9 KLTKVDKAAILLLSLGETDAAQVLRHMGPKEVQRVGVAMASMRNVHREQVEQVMGEFVEV 68 LT KAAILL+S+G +++V +++ +E++ + +A + + E + V+ EF E+ Sbjct: 14 ALTGKQKAAILLVSIGSEISSKVFKYLSQEEIESLTFEIAKLETITSELKDNVLLEFKEL 73 Query: 69 VGDQTSLGVGADGYIRKMLTQALGEDKANNLIDRILLGGSTSGLDSLKWMEPRAVADVIR 128 + Q + G Y R++L ++LG KA ++I+ + + + ++ +P + + I+ Sbjct: 74 MMAQEFIQKGGIDYARELLEKSLGTQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQ 133 Query: 129 YEHPQIQAIVVAYLDPDQAAEVLSHFDHKVRLDIVLRVSSLNTVQPSALKELNLILEKQF 188 EHPQ A++++YLDP +A+ +LS +V+ ++ R++ ++ P ++E+ +LEK+ Sbjct: 134 QEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREVERVLEKKL 193 Query: 189 AGNSNATRTTMGGVKRAADIMNYLDSSIEGQLMDSIREVDEDLSGQIEDLMFVFDNLADV 248 A S+ T+ GGV +I+N D E +++S+ E D +L+ +I+ MFVF+++ + Sbjct: 194 ASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEEEDPELAEEIKKKMFVFEDIVLL 253 Query: 249 DDRGIQALLREVSSDVLVLALKGSDEAIREKVFKNMSKRAAELLRDDLEAKGPVRVSEVE 308 DDR IQ +LRE+ L ALK D ++EK+FKNMSKRAA +L++D+E GP R +VE Sbjct: 254 DDRSIQRVLREIDGQELAKALKSVDIPVQEKIFKNMSKRAASMLKEDMEFLGPTRRKDVE 313 Query: 309 GAQKEILTIARRMAESGDIVLGGKGGEEMI 338 +Q++I+++ R++ E G+IV+ G E+++ Sbjct: 314 ESQQKIVSLIRKLEEQGEIVISRGGEEDVL 343
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 608 bits (1569), Expect = 0.0 Identities = 205/576 (35%), Positives = 310/576 (53%), Gaps = 39/576 (6%) Query: 30 LDNLSEMTMLRQIGLLVGLAASVAIGFAVVLWSQQPDYKPLYGSLNGVDANRVVEALTAA 89 L+ L+ + +I L+V +A+VAI A+VLW++ PDY+ L+ +L+ D +V LT Sbjct: 13 LEWLNRLRANPRIPLIVAGSAAVAIVVAMVLWAKTPDYRTLFSNLSDQDGGAIVAQLTQM 72 Query: 90 DIPYKVEPNSGALLVKADDLGRARMKVASAGVAPTDNNVGFEILDKEQALGTSQFMEATN 149 +IPY+ SGA+ V AD + R+++A G+ P VGFE+LD+E G SQF E N Sbjct: 73 NIPYRFANGSGAIEVPADKVHELRLRLAQQGL-PKGGAVGFELLDQE-KFGISQFSEQVN 130 Query: 150 YRRGLEGELARTVSSLNNVKAARVHLAIPKSSVFVRDDRKPSASVLVELYPGRSLEPSQV 209 Y+R LEGELART+ +L VK+ARVHLA+PK S+FVR+ + PSASV V L PGR+L+ Q+ Sbjct: 131 YQRALEGELARTIETLGPVKSARVHLAMPKPSLFVREQKSPSASVTVTLEPGRALDEGQI 190 Query: 210 MAIVNLVATSVPELDKSQVTVVDQKGNLLSDQQELSELTMAGKQFDFTRRMEGLLTQRVH 269 A+V+LV+++V L VT+VDQ G+LL+ Q S + Q F +E + +R+ Sbjct: 191 SAVVHLVSSAVAGLPPGNVTLVDQSGHLLT-QSNTSGRDLNDAQLKFANDVESRIQRRIE 249 Query: 270 NILQPVLGNGRYKAEVSADVDFSAVESTSEMYNPDQPA----LRSEQRNNEERQNSSGPQ 325 IL P++GNG A+V+A +DF+ E T E Y+P+ A LRS Q N E+ + P Sbjct: 250 AILSPIVGNGNVHAQVTAQLDFANKEQTEEHYSPNGDASKATLRSRQLNISEQVGAGYPG 309 Query: 326 GVPGALSNQPPGPASAPQQATASAPADYVAPGQPLKDANGQTIIDPKTGKPELAPYPTDK 385 GVPGALSNQP P AP + P P N Q T + P Sbjct: 310 GVPGALSNQPAPPNEAP----IATP--------PTNQQNAQNTPQTSTSTNSNSAGPRST 357 Query: 386 RDQTTRNYELDRSISYTKQQQGRLRRLSVAVVLDDQMKVDAKTGEVSHQPWSADELARFT 445 + T NYE+DR+I +TK G + RLSVAVV++ + D K P +AD++ + Sbjct: 358 QRNETSNYEVDRTIRHTKMNVGDIERLSVAVVVNYKTLADGKP-----LPLTADQMKQIE 412 Query: 446 RLVQDSVGYDASRGDSVSVINAPFAPVQAEEIDSIPFYSQPWFWDIVKQVLGVLFILVLV 505 L ++++G+ RGD+++V+N+PF +PF+ Q F D + L +LV+ Sbjct: 413 DLTREAMGFSDKRGDTLNVVNSPF-SAVDNTGGELPFWQQQSFIDQLLAAGRWLLVLVVA 471 Query: 506 F----GVLRPVLSNITGGGKGKSLAGGGGRDGDLALGESGLEGSLADDRVSIGGPSSILL 561 + +RP L+ K ++ E +E L+ D ++ L Sbjct: 472 WILWRKAVRPQLTRRVEEAKAAQEQAQVRQE-----TEEAVEVRLSKDEQLQQRRANQRL 526 Query: 562 PSPTEGYDAQLNAIKNLVAQDPGRVAQVVKEWINAD 597 G + I+ + DP VA V+++W++ D Sbjct: 527 -----GAEVMSQRIREMSDNDPRVVALVIRQWMSND 557
>FLGHOOKFLIE#Flagellar hook-basal body complex protein FliE signature. Length = 103 Score = 92.8 bits (230), Expect = 3e-28 Identities = 41/92 (44%), Positives = 55/92 (59%) Query: 18 QMEAMAKAKPVQAPAEVGAPSFSEMLSQAVDKVNETQQASTAMANAFEVGQSGVDLTDVM 77 Q++A A + Q SF+ L A+D++++TQ A+ A F +G+ GV L DVM Sbjct: 12 QLQATAMSARAQESLPQPTISFAGQLHAALDRISDTQTAARTQAEKFTLGEPGVALNDVM 71 Query: 78 IASQKASVSFQAMTQVRNKLVQAYQDIMQMPV 109 QKASVS Q QVRNKLV AYQ++M M V Sbjct: 72 TDMQKASVSMQMGIQVRNKLVAAYQEVMSMQV 103
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 504 bits (1300), Expect = e-179 Identities = 173/482 (35%), Positives = 255/482 (52%), Gaps = 18/482 (3%) Query: 2 AAKVLLVEDDRALREALSDTLLLGGHEFVAVDSAEAALPVLAREAFSLVISDVNMPGMDG 61 A +L+ +DD A+R L+ L G++ +A +A LV++DV MP + Sbjct: 3 GATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENA 62 Query: 62 HQLLGLIRTRYPHLPVLLMTAYGAVDRAVEAMRQGAADYLVKPF--------EARALLDL 113 LL I+ P LPVL+M+A A++A +GA DYL KPF RAL + Sbjct: 63 FDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 114 VARHALGQLPGSEEDGPVALEPASRQLLELAARVARSDSTVLISGESGTGKEVLANYIHQ 173 R + + + V A +++ + AR+ ++D T++I+GESGTGKE++A +H Sbjct: 123 KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHD 182 Query: 174 QSPRAGKPFIAINCAAIPDNMLEATLFGHEKGSFTGAIAAQPGKFELADGGTILLDEISE 233 R PF+AIN AAIP +++E+ LFGHEKG+FTGA G+FE A+GGT+ LDEI + Sbjct: 183 YGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGD 242 Query: 234 MPLGLQAKLLRVLQEREVERVGARKPINLDIRVLATTNRDLAAEVAAGRFREDLYYRLSV 293 MP+ Q +LLRVLQ+ E VG R PI D+R++A TN+DL + G FREDLYYRL+V Sbjct: 243 MPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNV 302 Query: 294 FPLAWRPLRERPADILPLAERLLRKHSRKMNLGAVALGPEAAQCLVRHAWPGNVRELDNA 353 PL PLR+R DI L +++ + K L EA + + H WPGNVREL+N Sbjct: 303 VPLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVRELENL 361 Query: 354 IQRALILQQGGLIQPADLCLTAPIGMPLAAPVPVPMPAMPPATPPSVE------IPSPAA 407 ++R L +I + +P + + + +VE S Sbjct: 362 VRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGD 421 Query: 408 GQDASGALGDDLRRREFQVIIDTLRTERGRRKEAAERLGISPRTLRYKLAQMRDAGMDVE 467 SG L E+ +I+ L RG + +AA+ LG++ TLR K +R+ G+ V Sbjct: 422 ALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKK---IRELGVSVY 478 Query: 468 AY 469 Sbjct: 479 RS 480
>PF06580#Sensor histidine kinase Length = 349 Score = 36.8 bits (85), Expect = 1e-04 Identities = 20/97 (20%), Positives = 32/97 (32%), Gaps = 19/97 (19%) Query: 299 LVENA----IQACGPELRLKVHLYARADSLRLSVSDNGPGMDPATLARLGEPFFTTKTTG 354 LVEN I ++ + ++ L V + G T Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT------------KES 310 Query: 355 TGLGLAVVKAVARAHQG---QLQLRSRPGRGTCATLI 388 TG GL V+ + G Q++L + G+ LI Sbjct: 311 TGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNAMVLI 347
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 510 bits (1314), Expect = 0.0 Identities = 181/489 (37%), Positives = 256/489 (52%), Gaps = 14/489 (2%) Query: 5 TKLLLIDDNLDRSRDLAVILNFLGEDQLTCNS--EDWREVAAGLSNSREALCVLLGSVES 62 +L+ DD+ L L+ G D ++ WR +AAG + V+ V Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGD-----LVVTDVVMP 58 Query: 63 KGGAVELLKQLASWDEYLPILLI-GEPAPADWPEELRRRVLASLEMPPSYNKLLDSLHRA 121 A +LL ++ LP+L++ + + + L P +L+ + RA Sbjct: 59 DENAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 122 QVYREMYDQARERGRSREPNLFRSLVGTSRAIQQVRQMMQQVADTDASVLILGESGTGKE 181 + R + LVG S A+Q++ +++ ++ TD +++I GESGTGKE Sbjct: 119 LAEP----KRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKE 174 Query: 182 VVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGHEKGAFTGAITSRAGRFELANGGT 241 +VAR LH + KRR GPFV +N AIP +L+ESELFGHEKGAFTGA T GRFE A GGT Sbjct: 175 LVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGT 234 Query: 242 LFLDEIGDMPLPMQVKLLRVLQERTFERVGSNKTQNVDVRIIAATHKNLEKMIEDGTFRE 301 LFLDEIGDMP+ Q +LLRVLQ+ + VG DVRI+AAT+K+L++ I G FRE Sbjct: 235 LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFRE 294 Query: 302 DLYYRLNVFPIEMAPLRERVEDIALLLNELISRMEHEKRGSIRFNSAAIMSLCRHDWPGN 361 DLYYRLNV P+ + PLR+R EDI L+ + + E E RF+ A+ + H WPGN Sbjct: 295 DLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAEKEGLDVKRFDQEALELMKAHPWPGN 354 Query: 362 VRELANLVERLAIMHPYGVIGVGELPKKFR-HVDDEDEQLASSLREELEERAAINAGLPG 420 VREL NLV RL ++P VI + + R + D + A++ L A+ + Sbjct: 355 VRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQ 414 Query: 421 MDAPAM-LPAEGLDLKDYLANLEQGLIQQALDDAGGVVARAAERLRIRRTTLVEKMRKYG 479 A LA +E LI AL G +AA+ L + R TL +K+R+ G Sbjct: 415 YFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELG 474 Query: 480 MSRRDDDLS 488 +S S Sbjct: 475 VSVYRSSRS 483
>FLAGELLIN#Flagellin signature. Length = 507 Score = 204 bits (519), Expect = 7e-62 Identities = 171/508 (33%), Positives = 243/508 (47%), Gaps = 22/508 (4%) Query: 2 ALTVNTNIASLNTQRNLNASSNDLNTSLQRLTTGYRINSAKDDAAGLQISNRLSNQISGL 61 A +NTN SL TQ NLN S + L+++++RL++G RINSAKDDAAG I+NR ++ I GL Sbjct: 1 AQVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGL 60 Query: 62 NVATRNANDGISLAQTAEGALQQSTNILQRIRDLALQSANGSNSDADRAALQKEVAAQQA 121 A+RNANDGIS+AQT EGAL + N LQR+R+L++Q+ NG+NSD+D ++Q E+ + Sbjct: 61 TQASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLE 120 Query: 122 ELTRISDTTTFGGRKLLDGSFGTTSFQVGSNAYETIDISLQNASASAIGSYQVGSNGAGT 181 E+ R+S+ T F G K+L QVG+N ETI I LQ ++G NG Sbjct: 121 EIDRVSNQTQFNGVKVLSQDN-QMKIQVGANDGETITIDLQKIDVKSLGLDGFNVNGPKE 179 Query: 182 VAS---------VAGTATASGIASGTVNLVGGGQVKNIAIAAGDSAKAIAEKMDGAIPNL 232 V G T + A+ V G V A K +G + Sbjct: 180 ATVGDLKSSFKNVTGYDTYAVGANKYRVDVNSGAVVTDTTAPTVPDKVYVNAANGQLTTD 239 Query: 233 SARART-VFTADVSGVTGGSLNFDVTVGSNTVSLAGVTSTQDLADQLNSNSSKLGITASI 291 A T V + T G+ G+ G T + + Sbjct: 240 DAENNTAVDLFKTTKSTAGTAEAKAIAGAIKGGKEGDTFDYKGVTFTIDTKTGNDGNGKV 299 Query: 292 NDKGVLTITSATGENVKFGAQTGTATAGQVAVKVQGS---------DGKFEAAAKNVVAA 342 + + T ++ GA A Q + V S D +AK Sbjct: 300 STTINGEKVTLTVADITAGAANVDAATLQSSKNVYTSVVNGQFTFDDKTKNESAKLSDLE 359 Query: 343 GTAATTTIVTGYVQLNSPTAYSVSGTGTQA--SQVFGNASAAQKSSVASVDISTADGAQN 400 A V TA + T A + ++ + + + N Sbjct: 360 ANNAVKGESKITVNGAEYTANAAGDKVTLAGKTMFIDKTASGVSTLINEDAAAAKKSTAN 419 Query: 401 AIAVVDNALAAIDAQRADLGAVQNRFKNTIDNLTNISENATNARSRIKDTDFAAETAALS 460 +A +D+AL+ +DA R+ LGA+QNRF + I NL N N +ARSRI+D D+A E + +S Sbjct: 420 PLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATEVSNMS 479 Query: 461 KNQVLQQAGTAILAQANQLPQAVLSLLR 488 K Q+LQQAGT++LAQANQ+PQ VLSLLR Sbjct: 480 KAQILQQAGTSVLAQANQVPQNVLSLLR 507
>FLAGELLIN#Flagellin signature. Length = 507 Score = 52.4 bits (125), Expect = 2e-09 Identities = 31/141 (21%), Positives = 60/141 (42%) Query: 1 MRISTIQAFNNSVSGISRNYADLTRTQAEISAGKRLLTPADDPVGAVRLLQLNQEQALNS 60 I+T + + ++++ + L+ +S+G R+ + DD G + + Sbjct: 2 QVINTNSLSLLTQNNLNKSQSSLSSAIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLT 61 Query: 61 QYKSGITAAKNSLQQEETILNSVGTVIHRIREIAVQAGNGGLDASDKNALATELAQREDE 120 Q + Q E LN + + R+RE++VQA NG SD ++ E+ QR +E Sbjct: 62 QASRNANDGISIAQTTEGALNEINNNLQRVRELSVQATNGTNSDSDLKSIQDEIQQRLEE 121 Query: 121 LLNLLNSRDASGKYLFSGSQG 141 + + N +G + S Sbjct: 122 IDRVSNQTQFNGVKVLSQDNQ 142 Score = 31.9 bits (72), Expect = 0.005 Identities = 15/77 (19%), Positives = 35/77 (45%) Query: 349 DAVGVAISNLDSSNSQILTGQGRIGARMNVAESTETFIDDVTLVNTAVISQIQDLDYPEA 408 + ++++DS+ S++ + +GA N +S T + + + S+I+D DY Sbjct: 415 KSTANPLASIDSALSKVDAVRSSLGAIQNRFDSAITNLGNTVTNLNSARSRIEDADYATE 474 Query: 409 LSRLTLQSTIMDAAQQS 425 +S ++ + A Sbjct: 475 VSNMSKAQILQQAGTSV 491
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 246 bits (629), Expect = 2e-75 Identities = 141/450 (31%), Positives = 232/450 (51%), Gaps = 19/450 (4%) Query: 2 SDLLSIGLSGLGTSQTWLTVTGHNITNVKTPGYSRQDAIQQTRIPQFSGAGYMGSGSQIV 61 S L++ +SGL +Q L +NI++ GY+RQ I G++G+G + Sbjct: 1 SSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQANSTLGAGGWVGNGVYVS 60 Query: 62 DVRRLASDFLTGQLRNATSQNSELNAFLGQIDQLNSLLADNTTGVSPAMQRFFSALQTAA 121 V+R F+T QLR A +Q+S L A Q+ +++++L+ +T+ ++ MQ FF++LQT Sbjct: 61 GVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTSTSSLATQMQDFFTSLQTLV 120 Query: 122 QNPSSTEAREAVLAQAQGLSKTFNTLYDQLDKQNSLINQQLGALTSQVNNLSQSVAEYND 181 N AR+A++ +++GL F T L Q+ +N +GA Q+NN ++ +A ND Sbjct: 121 SNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNIAIGASVDQINNYAKQIASLND 180 Query: 182 AIAK--AKSAGAVPNDLLDARDEAVRKLSEMVGVTAVTQDDNSVSLFIGSGQPLVVGNTV 239 I++ AGA PN+LLD RD+ V +L+++VGV QD + ++ + +G LV G+T Sbjct: 181 QISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVSVQDGGTYNITMANGYSLVQGSTA 240 Query: 240 STLSVVPGLDDPTRYQVQLTLGDS--TQNVTRLVSGGQMGGLLAYRDTVLDSSYNKLGQL 297 L+ VP DP+R V G + + +L++ G +GG+L +R LD + N LGQL Sbjct: 241 RQLAAVPSSADPSRTTVAYVDGTAGNIEIPEKLLNTGSLGGILTFRSQDLDQTRNTLGQL 300 Query: 298 ALTFADTVNKQLGQGLDLAGKAGANLFGDINDPDITALRVLAKNGNTGNVHANLNITDTS 357 AL FA+ N Q G D G AG + F I VL N G+V +TD S Sbjct: 301 ALAFAEAFNTQHKAGFDANGDAGEDFF------AIGKPAVLQNTKNKGDVAIGATVTDAS 354 Query: 358 KLNSSDFRLDFDGTNFTARRLGDDASMQVTVSGTGPYTLSFKDANGVDQGFSVTLDQLPA 417 + ++D+++ FD + RL + + VT + G +T PA Sbjct: 355 AVLATDYKISFDNNQWQVTRLASNTTFTVT---------PDANGKVAFDGLELTFTGTPA 405 Query: 418 AGDRFTLQPTRRGASDIETTLKNASQLAFA 447 D FTL+P +++ + + +++A A Sbjct: 406 VNDSFTLKPVSDAIVNMDVLITDEAKIAMA 435 Score = 83.1 bits (205), Expect = 8e-19 Identities = 51/156 (32%), Positives = 71/156 (45%), Gaps = 20/156 (12%) Query: 545 GSGQTYTYEFNLSNVPQTGDSFTLSFNKDGIAD--------------------NRNALNL 584 G E + P DSFTL D I + + + N Sbjct: 389 GKVAFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASEEDAGDSDNRNG 448 Query: 585 NALQTKPTVGGTDSTGSTYNDAYGGLVERVGTLTAQARASADASQTVLKQAQDSRDSLSG 644 AL + T ++NDAY LV +G TA + S+ V+ Q + + S+SG Sbjct: 449 QALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSISG 508 Query: 645 VSLDEEAANLIQFQQYYSASAQVIQVARSLFDTLIG 680 V+LDEE NL +FQQYY A+AQV+Q A ++FD LI Sbjct: 509 VNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALIN 544
>FLGFLGJ#Flagellar protein FlgJ signature. Length = 313 Score = 148 bits (374), Expect = 1e-43 Identities = 79/195 (40%), Positives = 114/195 (58%), Gaps = 7/195 (3%) Query: 198 LPAQSYPAASRRGFSTDGVDSQGSRRIAQP-----PLARGKSMFASADEFIATMLPMAQK 252 LP +S PAA F + V ++ ++Q P S+ + F+A + AQ Sbjct: 104 LPEESTPAA-PMKFPLETVVRYQNQALSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPAQL 162 Query: 253 AAERIGVDARYLVAQAALETGWGKSIIRQQDGGSSHNLFGIKTGSRWDGASARALTTEYE 312 A+++ GV ++AQAALE+GWG+ IR+++G S+NLFG+K W G TTEYE Sbjct: 163 ASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITTTEYE 222 Query: 313 GGKAVKEVAAFRSYSSFEQSFHDYVSFLQGNDRYQNALDSAANPERFMQELQRAGYATDP 372 G+A K A FR YSS+ ++ DYV L N RY A+ +AA+ E+ Q LQ AGYATDP Sbjct: 223 NGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYA-AVTTAASAEQGAQALQDAGYATDP 281 Query: 373 QYARKVAQIARQMQT 387 YARK+ + +QM++ Sbjct: 282 HYARKLTNMIQQMKS 296 Score = 68.2 bits (166), Expect = 7e-15 Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 10/160 (6%) Query: 20 DLNRLNQLKVGKDRDGEANIRKVAQEFESLFLNEMLKSMRSANEALGDGNFMNSQTTKQY 79 D LN+LK D ANIR VA++ E +F+ MLKSMR +AL +S+ T+ Y Sbjct: 14 DAQSLNELKAKAGEDPAANIRPVARQVEGMFVQMMLKSMR---DALPKDGLFSSEHTRLY 70 Query: 80 QDMYDQQLSVSLSKNAGGIGLADVLVRQLSKMKQGSRGNGENPFARVAENGAGRWPSNPS 139 MYDQQ++ ++ G+GLA+++V+Q++ + + + R+ + Sbjct: 71 TSMYDQQIAQQMT-AGKGLGLAEMMVKQMTPEQPLPEESTPAAPMKFPLETVVRYQNQAL 129 Query: 140 AQAGKALPMPEAGRDDSKLLNQR----RLALPGKLAERML 175 +Q DDS + + +L+LP +LA + Sbjct: 130 SQL--VQKAVPRNYDDSLPGDSKAFLAQLSLPAQLASQQS 167
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 83.3 bits (206), Expect = 8e-21 Identities = 35/127 (27%), Positives = 62/127 (48%) Query: 2 RILLVEDHPQLAESVVQALKGAGWTVDLLQDGVAADLALASEEYALAILDVGLPRMDGFE 61 IL+ +D + + QAL AG+ V + + +A+ + L + DV +P + F+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 VLARLRGRGKTLPVLMLTARGEVKDRVHGLNLGADDYLAKPFELSELEARVKALLRRSVL 121 +L R++ LPVL+++A+ + GA DYL KPF+L+EL + L Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 122 GGEQLQR 128 +L+ Sbjct: 125 RPSKLED 131
>AEROLYSIN#Aerolysin signature. Length = 493 Score = 28.8 bits (64), Expect = 0.028 Identities = 16/40 (40%), Positives = 23/40 (57%) Query: 2 MMKLSFRPLALVAAGLLLAGAAVAEPKRPECIAPASPGGG 41 M K+ L+L+ +GLL+A A AEP P+ + S G G Sbjct: 1 MQKIKLTGLSLIISGLLMAQAQAAEPVYPDQLRLFSLGQG 40
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 26.7 bits (59), Expect = 0.044 Identities = 15/58 (25%), Positives = 25/58 (43%), Gaps = 5/58 (8%) Query: 99 LGFILSAALVGSCMAILYGARPIPAVVTASLL-----GIGLYWLFDRALDVPLPLGVL 151 +S +V C+A LY + IP V + + LF++ DV +G+L Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLL 931
>PF05043#Transcriptional activator Length = 493 Score = 29.9 bits (67), Expect = 0.010 Identities = 7/27 (25%), Positives = 16/27 (59%) Query: 47 YRYIKHTSKLIRRLGDSDLALQRNKVV 73 YR I +K+I+R +++L +++ Sbjct: 118 YRIISQINKVIKRQFQFEVSLTPVQII 144
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 49.9 bits (119), Expect = 8e-09 Identities = 32/155 (20%), Positives = 66/155 (42%), Gaps = 2/155 (1%) Query: 26 LPQVAGDLRVSIPSAGWLISGYAFAVAFGAPLMAMATARLERKKALLALMGIFIVGNLLC 85 LP +A D S W+ + + + G + + +L K+ LL + I G+++ Sbjct: 37 LPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIG 96 Query: 86 AVAANY-GLLMLARIVTALCHGAFFGIGSVVAASLVAPNRRASAVALMFTGLTLANVLGV 144 V ++ LL++AR + AF + VV A + R A L+ + + + +G Sbjct: 97 FVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGP 156 Query: 145 PLGTALGQEAGWRATFWVVTLIGVVAFVGLARVLP 179 +G + W ++ +I ++ L ++L Sbjct: 157 AIGGMIAHYIHWSYLL-LIPMITIITVPFLMKLLK 190
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 35.2 bits (81), Expect = 0.001 Identities = 40/179 (22%), Positives = 69/179 (38%), Gaps = 55/179 (30%) Query: 1 MTALTLGLIGNPNSGKTTLFNQL---TGSRQRVGNW-AGVTV------ERKEG------- 43 M + +G++ + ++GKTTL L +G+ +G+ G T ER+ G Sbjct: 1 MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGI 60 Query: 44 -AFHTVRHAVRLVDLPGTYSLTSVSAQASLDEQIACRYIASGEVDVLVNVVDAANL---- 98 +F V ++D PG + EV ++V+D A L Sbjct: 61 TSFQWENTKVNIIDTPGHMDFLA-------------------EVYRSLSVLDGAILLISA 101 Query: 99 -----ERNLYLTVQLREMGIPCIVALNMLDIARSQRIRIDIDGLAR----RLGCPVVPL 148 + L LR+MGIP I +N +D + ID+ + + +L +V Sbjct: 102 KDGVQAQTRILFHALRKMGIPTIFFINKID-----QNGIDLSTVYQDIKEKLSAEIVIK 155
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 30.4 bits (68), Expect = 0.009 Identities = 22/111 (19%), Positives = 40/111 (36%) Query: 95 EEAAGRLDDIRGKVVASESSVTSEREALRLQVKQLQEKLGSQERQQADVSNQFGGQGKRL 154 E+A + A ++ +E+ AL + +L++ L S + Sbjct: 231 EKALEGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEK 290 Query: 155 DQLASDLKAQQESAAQLVAQLDGKLQTLAAEQEKLKALQVELGKTNEQLKA 205 L ++ + + L A + L A +E K L+ E K EQ K Sbjct: 291 AALEAEKADLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQNKI 341
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 109 bits (274), Expect = 1e-29 Identities = 81/362 (22%), Positives = 130/362 (35%), Gaps = 68/362 (18%) Query: 1 MRILVTGATGFIGGRFARFALEQGLSVRV---------SGRRADAVEHLVARGAEFVPGD 51 M+ LVTGA GFIG ++ LE G V + +E L G +F D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 52 LADPALVLRLCED--VEAVVHCAGAVGV---WGPRERFLAANVGLAESVVEACMRQKVRR 106 LAD + L E V + V + +N+ +++E C K++ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQH 120 Query: 107 LVHLSSPSIYFDGRDHLDLNEEYVPRRFSDHYGATKYQAEQLVLSARDL-GLEVLALRPR 165 L++ SS S+Y R + + + Y ATK E + + L GL LR Sbjct: 121 LLYASSSSVYGLNR-KMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLR-F 178 Query: 166 FVV----GAGDTSIFPRMIQAHRKGR-LRILGNGLNRVDFTSVHNLNDALFSCL------ 214 F V G D ++F + +A +G+ + + G + DFT + ++ +A+ Sbjct: 179 FTVYGPWGRPDMALF-KFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 215 ------LAGEPALG----KVYNISNGQPVPFWDAVNYVMRQLDLPPVGGHLPYAVGYGLA 264 G PA +VYNI N PV D + + L + LP Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLPL------- 290 Query: 265 ALNEGVCRILPGRPEPVLFRLGMAVMAKNFTLDINRAREYLDYDPRVSLWTALDEFCAWW 324 +P VL D E + + P ++ + F W+ Sbjct: 291 ------------QPGDVLETSA----------DTKALYEVIGFTPETTVKDGVKNFVNWY 328 Query: 325 RA 326 R Sbjct: 329 RD 330
>FLAGELLIN#Flagellin signature. Length = 507 Score = 30.8 bits (69), Expect = 0.004 Identities = 13/42 (30%), Positives = 20/42 (47%), Gaps = 5/42 (11%) Query: 55 SARD--AGLA---TLRFNFRGVGQSAGSYGEGIGEIDDAEAA 91 SA+D AG A N +G+ Q++ + +GI E A Sbjct: 39 SAKDDAAGQAIANRFTSNIKGLTQASRNANDGISIAQTTEGA 80
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 71.4 bits (175), Expect = 5e-15 Identities = 54/150 (36%), Positives = 68/150 (45%), Gaps = 17/150 (11%) Query: 33 VDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKVGTTGDDVDLALLVDGLQAEREQGITI 92 VD GK+TL LL++S I E K T D+ L ER++GITI Sbjct: 12 VDAGKTTLTESLLYNSGAITE------LGSVDKGTTRTDNTLL---------ERQRGITI 56 Query: 93 DVAYRYFSTAKRKFIIADTPGHEQYTRNMATGASTCDLAIILIDARYGVQTQTRRHSFIA 152 F K I DTPGH + + S D AI+LI A+ GVQ QTR Sbjct: 57 QTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHAL 116 Query: 153 SLLGIRHIVVAINKMDLKGFD-QGVFEQIK 181 +GI I INK+D G D V++ IK Sbjct: 117 RKMGIPTIFF-INKIDQNGIDLSTVYQDIK 145
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 453 bits (1166), Expect = e-161 Identities = 127/406 (31%), Positives = 225/406 (55%), Gaps = 14/406 (3%) Query: 11 FVWEGTDKKGTKVKGELSSQNPTLVKAQLRKQGITPVKVR-------KKGISLLGA--GK 61 + ++ D +G K +G + + + LR++G+ P+ V K G + L Sbjct: 4 YHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLRRKI 63 Query: 62 KIKPMDIALFTRQMSTMMAAGVPLLQSFDIISEGFDNPNMRKLVEEIKQEVAGGNSLANS 121 ++ D+AL TRQ++T++AA +PL ++ D +++ + P++ +L+ ++ +V G+SLA++ Sbjct: 64 RLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSLADA 123 Query: 122 LRKKPQYFDSLYCNLVDAGEQSGALETLLDRVATYKEKTEALKAKIKKAMTYPIAVIVVA 181 ++ P F+ LYC +V AGE SG L+ +L+R+A Y E+ + ++++I++AM YP + VVA Sbjct: 124 MKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLTVVA 183 Query: 182 IIVSAILLIKVVPQFQSVFEGFGAELPAFTMMVINISNVLQEW--WLLVLLMMGGAGFLL 239 I V +ILL VVP+ F LP T +++ +S+ ++ + W+L+ L+ G F + Sbjct: 184 IAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMAFRV 243 Query: 240 NHAYKRSEKFRDATDRTVLKLPIVGAILYKSAVARYARTLSTTFAAGVPLVEALDSVSGA 299 R EK R + R +L LP++G I ARYARTLS A+ VPL++A+ Sbjct: 244 ---MLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 300 TGNVVFRDAVGKIKQDVSTGMQLNFSMRTTNIFPSMAIQMTAIGEESGALDDMLAKVAGF 359 N R + V G+ L+ ++ T +FP M M A GE SG LD ML + A Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 360 YEQEVDNAVDNLTALMEPMIMAVLGVLVGGLIIAMYLPIFQLGNVV 405 ++E + + L EP+++ + +V +++A+ PI QL ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 354 bits (909), Expect = e-125 Identities = 165/283 (58%), Positives = 195/283 (68%), Gaps = 1/283 (0%) Query: 3 LLDYLASHPLAFVLCTILLGLLVGSFLNVVVHRLPKMMERNWKAEAREALGLEPE-PKQA 61 LL+ P + L L++GSFLNVV+HRLP M+ER W+AE R + E + Sbjct: 4 LLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGVDEP 63 Query: 62 TYNLVLPNSACPRCGHEIRPWENIPLVSYLALGGKCSSCKAAIGKRYPLVELATALLSGY 121 YNL++P S CP C H I ENIPL+S+L L G+C C+A I RYPLVEL TALLS Sbjct: 64 PYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALLSVA 123 Query: 122 VAWHFGFTWQAGAMLLLTWGLLAMSLIDADHQLLPDVLVLPLLWLGLIANHFGLFASLDD 181 VA W A LLLTW L+A++ ID D LLPD L LPLLW GL+ N G F SL D Sbjct: 124 VAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVSLGD 183 Query: 182 ALFGAVFGYLSLWSVFWLFKLVTGKEGMGYGDFKLLAMLGAWGGWQILPLTILLSSLVGA 241 A+ GA+ GYL LWS++W FKL+TGKEGMGYGDFKLLA LGAW GWQ LP+ +LLSSLVGA Sbjct: 184 AVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSLVGA 243 Query: 242 ILGVIMLRLRNAESGTPIPFGPYLAIAGWIALLWGDQITRTYL 284 +G+ ++ LRN PIPFGPYLAIAGWIALLWGD ITR YL Sbjct: 244 FMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 30.0 bits (67), Expect = 0.005 Identities = 23/88 (26%), Positives = 32/88 (36%), Gaps = 11/88 (12%) Query: 5 WILGLTGGIGSGKSAAAEHFISLGVHLVDADHAARW--VVEPGRPALAKIVERFGDGILL 62 +I G GIG A A S G H+ D+ V A A+ E F Sbjct: 12 FITGAAQGIGE---AVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF------ 62 Query: 63 PDGQLDRAALRERIFQAPEERRWLEQLL 90 P D AA+ E + E ++ L+ Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILV 90
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 27.6 bits (61), Expect = 0.013 Identities = 5/25 (20%), Positives = 10/25 (40%) Query: 66 RRGYLQHLVVDPGYRGLGLARRMLD 90 ++ + V YR G+ +L Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLH 112
>2FE2SRDCTASE#Ferric iron reductase signature. Length = 262 Score = 26.5 bits (58), Expect = 0.041 Identities = 10/24 (41%), Positives = 12/24 (50%) Query: 36 DHPHPPRQVTLVQWEHIEALGTLL 59 D P P +TL QW L +LL Sbjct: 47 DEPAPLNAMTLAQWSSPNVLSSLL 70
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 36.8 bits (85), Expect = 3e-04 Identities = 32/226 (14%), Positives = 69/226 (30%), Gaps = 19/226 (8%) Query: 256 QRYYRAAYQLPLGSRGTRIGLAHAETTYRLVRDFSRLDAHGRAITDSLFVSQPLLRSRSL 315 Y+ A G I + A+ + L V+Q L R+ +L Sbjct: 484 SGYFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTL 543 Query: 316 SLS-TQLQYENKRLRDDQERTG-RHSRKEIRLWTASISGNAQDRLFGGGQS-----GFSL 368 LS + Y D+Q + G + ++I ++S + + G+ ++ Sbjct: 544 YLSGSHQTYWGTSNVDEQFQAGLNTAFEDINW---TLSYSLTKNAWQKGRDQMLALNVNI 600 Query: 369 AYAHGQLAIDSGEERLLDRYTIGTAGSFDKIMLNAVRLQHLGDRLQLFAQLNAQWSGGNL 428 ++H + + R + ++ A L + L + ++GG Sbjct: 601 PFSHWLRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGD 660 Query: 429 DSAEQFDMG-----GPYGVRAFPLGSYKGYGDEGWQASAELRYSLA 469 ++ G YG + D+ Q + + Sbjct: 661 GNSGSTGYATLNYRGGYGN----ANIGYSHSDDIKQLYYGVSGGVL 702
>PF05860#haemagglutination activity domain. Length = 117 Score = 65.6 bits (160), Expect = 8e-15 Identities = 31/93 (33%), Positives = 52/93 (55%), Gaps = 5/93 (5%) Query: 71 TDGRHMVID---QQSHKLITNWNEFSVRADERVSFHQPGQDAVALNRVIGRNGSDIQGRI 127 T+G +I+ Q L ++ EFSV F+ P ++RV G + S+I G I Sbjct: 17 TEGNTRIIERGTQAGSNLFHSFQEFSVPTSGTAFFNNPTNIQNIISRVTGGSVSNIDGLI 76 Query: 128 DANGK--VFLVNPNGVVFGKSAQVNVGGLVAST 158 AN +FL+NPNG++FG++A++++GG + Sbjct: 77 RANATANLFLINPNGIIFGQNARLDIGGSFVGS 109
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 42.9 bits (101), Expect = 4e-06 Identities = 50/266 (18%), Positives = 94/266 (35%), Gaps = 45/266 (16%) Query: 551 MLEGEREKLLRMEQELHRRVIGQDEAVVAVSNAVRRSRAGLADPNRPSGSFLFLGPTGVG 610 + KL Q+ ++G+ A+ + + R L + + G +G G Sbjct: 121 EPKRRPSKLEDDSQDGMP-LVGRSAAMQEIYRVLAR----LMQTDLT---LMITGESGTG 172 Query: 611 KTELCKALAEFLFDTEEALVRIDMSEFMEKHSVARLIGAPPGYVGFEEGGYLTEAIRRKP 670 K + +AL ++ V I+M+ + L G E G T A R Sbjct: 173 KELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQTRST 224 Query: 671 YSV-------VLLDEVEKAHPDVFNILLQVLEDG---RLTDSHGRTVDFRNTVVVMTSNL 720 + LDE+ D LL+VL+ G + D R +V +N Sbjct: 225 GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAATN- 280 Query: 721 GSAQIQELAGDREAQRAAVMDAVNAHFRPEFINRIDEVVVFEPLAREQIAGIAEIQLGRL 780 ++L + ++ FR + R++ V + P R++ I ++ + Sbjct: 281 -----KDL-------KQSINQ---GLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFV 325 Query: 781 RKRLAERELSLELSQEALDKLIAVGF 806 ++ E QEAL+ + A + Sbjct: 326 QQAEKEGLDVKRFDQEALELMKAHPW 351 Score = 34.4 bits (79), Expect = 0.002 Identities = 25/177 (14%), Positives = 59/177 (33%), Gaps = 32/177 (18%) Query: 49 LLMQVGFDIAALRSGLNKELDALPKIQSPTGDVNLSQDLARLLNQADRLAQQKGDQFISS 108 L + G+D+ + I + GD+ ++ D+ + + + Sbjct: 22 ALSRAGYDVRITSNAA----TLWRWIAAGDGDLVVT-DV--------VMPDENAFDLLPR 68 Query: 109 ELVLLAAMDENTRLGKLLLGQGVSRKALENAVANLRGGEA-------VNDPNVEESRQAL 161 + + + ++ Q A+ G + +AL Sbjct: 69 ----IKKARPDLPV-LVMSAQN----TFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 162 DKYTVDMTKRAEEG-KLDPVIGRDDEIRRTIQVLQRRTKNN-PVLI-GEPGVGKTAI 215 + +K ++ P++GR ++ +VL R + + ++I GE G GK + Sbjct: 120 AEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELV 176
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 525 bits (1353), Expect = 0.0 Identities = 176/477 (36%), Positives = 261/477 (54%), Gaps = 33/477 (6%) Query: 1 MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDG 60 M+ L+ DD+ IR +L L R D R N +A DL +TD+ +PD Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGLDLVQYIQQRHPQTPVAMITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALR 120 + DL+ I++ P PV +++A + TAI+A + GA+D+L KP DL L ++ AL Sbjct: 61 NAFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120 Query: 121 LRNPEAEEAPVDNR----LLGESPPMRALRNQIGKLARSQAPVYISGESGSGKELVARLI 176 + D++ L+G S M+ + + +L ++ + I+GESG+GKELVAR + Sbjct: 121 EPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL 180 Query: 177 HEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEV 236 H+ G R PFV +N AIP +L+ESE FGH+KG+FTGA G F+ A GGTLFLDE+ Sbjct: 181 HDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEI 240 Query: 237 ADLPMAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRL 296 D+PM Q +LLR +Q+ VGG+ + DVRI+ AT+KDL + G FR+DLYYRL Sbjct: 241 GDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRL 300 Query: 297 NVIELRVPPLRERREDIPLLADRILKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELE 356 NV+ LR+PPLR+R EDIP L +++ + GL R +A E +K + +PGNVRELE Sbjct: 301 NVVPLRLPPLRDRAEDIPDLVRHFVQQAEKE-GLDVKRFDQEALELMKAHPWPGNVRELE 359 Query: 357 NMLERAYTLCEDDQIQPHDLRL---------ADAPGASQEGAASLSEI------------ 395 N++ R L D I + A++ G+ S+S+ Sbjct: 360 NLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASF 419 Query: 396 -------DNLEDYLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID 445 + L ++E LI+ AL TR N+ AA LGL ++R ++++LG+ Sbjct: 420 GDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 41.8 bits (98), Expect = 1e-07 Identities = 18/49 (36%), Positives = 31/49 (63%), Gaps = 3/49 (6%) Query: 4 RQKGFTLLEMVVVVAVIGILLGIAIPSYQNYVIRSNRTEGQALLSDAAA 52 +Q+GFTLLE++VV+ +IG+L + +P N + + + Q +SD A Sbjct: 6 KQRGFTLLEIMVVIVIIGVLASLVVP---NLMGNKEKADKQKAVSDIVA 51
>PF06704#DspF/AvrF protein Length = 129 Score = 27.5 bits (61), Expect = 0.033 Identities = 10/28 (35%), Positives = 18/28 (64%), Gaps = 2/28 (7%) Query: 194 KNDIC--YATQNRQDAVKELADQCDMVL 219 +N +C Y +Q+ + AV E+ D +MV+ Sbjct: 26 QNGVCALYDSQDNEAAVIEMPDHSEMVI 53
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 33.8 bits (77), Expect = 1e-04 Identities = 21/54 (38%), Positives = 33/54 (61%), Gaps = 5/54 (9%) Query: 8 GQESRVTLHFALKLEDGNVVDSTFDK--QPASFKVGDGNLLPGFEQALFGLKAG 59 G+ VT+ + L DG V DST +K +PA+F+V ++PG+ +AL + AG Sbjct: 142 GKSDTVTVEYTGTLIDGTVFDST-EKAGKPATFQV--SQVIPGWTEALQLMPAG 192
>PF05844#YopD protein Length = 295 Score = 28.8 bits (64), Expect = 0.038 Identities = 34/123 (27%), Positives = 51/123 (41%), Gaps = 21/123 (17%) Query: 226 VSPGADVYSVGAALGAALTARLPGHEAQV---QVSQQVLDGLKRQTRTFTYLLAGLGIIS 282 ++PGA SVG AA ++P A +QVLD R + L + + ++ Sbjct: 20 IAPGAAGRSVGTPQAAAELPQVPAARADRVELNAPRQVLDP-VRMEAAGSELDSSVELLL 78 Query: 283 LLGGGVGVMNVMLMSVAERRREIGVRMALGARQRDIRNLFLIEAVTLTAAGALSGAVLGV 342 +L +A++ RE+GV QRD N +I A SGA L + Sbjct: 79 IL-----------FRIAQKARELGVL------QRDNENQAIIHAQKAQVDEMRSGATLMI 121 Query: 343 AAA 345 A A Sbjct: 122 AMA 124
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 34.6 bits (79), Expect = 8e-05 Identities = 21/141 (14%), Positives = 50/141 (35%), Gaps = 8/141 (5%) Query: 7 ATMGELAELAGVSRATLNRHCGTREGL-KRRLESHARSTLERLTHSAALQRLEPREALRE 65 ++GE+A+ AGV+R + H + L E + E A +P LRE Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 66 LIREHL-------AQRDLLALLMFEQNPGRQAGHGDASWQSYVEALDAFFLRGQQKRVFR 118 ++ L +R L+ ++ + + + ++ + + + Sbjct: 92 ILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEA 151 Query: 119 IDISAATFSELFIVLIYGMVD 139 + A + +++ G + Sbjct: 152 KMLPADLMTRRAAIIMRGYIS 172
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 1169 bits (3026), Expect = 0.0 Identities = 517/1028 (50%), Positives = 715/1028 (69%), Gaps = 8/1028 (0%) Query: 1 MSEFFIKRPNFAWVVALFISLAGLLVISKLPVAQYPNVAPPQITITATYPGASAKVLVDS 60 M+ FFI+RP FAWV+A+ + +AG L I +LPVAQYP +APP ++++A YPGA A+ + D+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 61 VTSVLEESLNGAKGLLYFESTNNSNGTAEIVVTFEPGTDPDLAQVDVQNRLKKAEARMPQ 120 VT V+E+++NG L+Y ST++S G+ I +TF+ GTDPD+AQV VQN+L+ A +PQ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 121 AVLTQGLQVEQTSAGFLLIYALSYKEGAQRSDTTALGDYAARNINNELRRLPGVGKLQFF 180 V QG+ VE++S+ +L++ D + DY A N+ + L RL GVG +Q F Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDD--ISDYVASNVKDTLSRLNGVGDVQLF 178 Query: 181 SSEAAMRVWIDPQKLVGFGLSIDDVSNAIRGQNVQVPAGAFGSAPGSSAQELTATLAVKG 240 ++ AMR+W+D L + L+ DV N ++ QN Q+ AG G P Q+L A++ + Sbjct: 179 GAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQT 238 Query: 241 TLDDPQEFGQVVLRANQDGSLVRLADVARLELGKESYNISSRLNGTPTVGGAIQLSPGAN 300 +P+EFG+V LR N DGS+VRL DVAR+ELG E+YN+ +R+NG P G I+L+ GAN Sbjct: 239 RFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGAN 298 Query: 301 AIQTATLVKQRLAELSAFFPEDMQYSVPYDTSRFVDVAIEKVIHTLIEAMVLVFLVMFLF 360 A+ TA +K +LAEL FFP+ M+ PYDT+ FV ++I +V+ TL EA++LVFLVM+LF Sbjct: 299 ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358 Query: 361 LQNVRYTLIPSIVVPVCLLGTLMVMYLLGFSVNMMTMFGMVLAIGILVDDAIVVVENVER 420 LQN+R TLIP+I VPV LLGT ++ G+S+N +TMFGMVLAIG+LVDDAIVVVENVER Sbjct: 359 LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418 Query: 421 IMAEEGISPAEATVKAMKQVSGAIVGITLVLSAVFLPLAFMAGSVGVIYQQFSVSLAVSI 480 +M E+ + P EAT K+M Q+ GA+VGI +VLSAVF+P+AF GS G IY+QFS+++ ++ Sbjct: 419 VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478 Query: 481 LFSGFLALTFTPALCATLLKPIPEGHHE-KRGFFGAFNRGFARVTERYSLLNSKLVARAG 539 S +AL TPALCATLLKP+ HHE K GFFG FN F Y+ K++ G Sbjct: 479 ALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTG 538 Query: 540 RFMLVYAGLVAMLGYFYLRLPEAFVPAEDLGYMVVDVQLPPGASRVRTDATGEE-LERFL 598 R++L+YA +VA + +LRLP +F+P ED G + +QLP GA++ RT ++ + +L Sbjct: 539 RYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYL 598 Query: 599 KSREA-VASVFLISGFSFSGQGDNAALAFPTFKDWSER-GAEQSAAAEIAALNEHFALPD 656 K+ +A V SVF ++GFSFSGQ NA +AF + K W ER G E SA A I Sbjct: 599 KNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIR 658 Query: 657 DGTVMAVSPPPINGLGNSGGFALRLMDRSGVGREALLQARDTLLGEIQTNPKFLYAMM-E 715 DG V+ + P I LG + GF L+D++G+G +AL QAR+ LLG +P L ++ Sbjct: 659 DGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 716 GLAEAPQLRLLIDREKARALGVSFETISGTLSAAFGSEVINDFTNAGRQQRVVIQAEQGN 775 GL + Q +L +D+EKA+ALGVS I+ T+S A G +NDF + GR +++ +QA+ Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 776 RMTPESVLELYVPNAAGNLVPLSAFVSVKWEEGPVQLVRYNGYPSIRIVGDAAPGFSTGE 835 RM PE V +LYV +A G +VP SAF + W G +L RYNG PS+ I G+AAPG S+G+ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 836 AMAEMERLAAQLPAGIGYEWTGLSYQEKVSAGQATSLFALAILVVFLLLVALYESWSIPL 895 AMA ME LA++LPAGIGY+WTG+SYQE++S QA +L A++ +VVFL L ALYESWSIP+ Sbjct: 839 AMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPV 898 Query: 896 SVMLIVPIGAIGAVLAVMVSGMSNDVYFKVGLITIIGLSAKNAILIVEFAKELWE-QGHS 954 SVML+VP+G +G +LA + NDVYF VGL+T IGLSAKNAILIVEFAK+L E +G Sbjct: 899 SVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKG 958 Query: 955 LRDAAIEAARLRFRPIIMTSMAFILGVIPLALASGAGAASQRAIGTGVIGGMLSATFLGV 1014 + +A + A R+R RPI+MTS+AFILGV+PLA+++GAG+ +Q A+G GV+GGM+SAT L + Sbjct: 959 VVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAI 1018 Query: 1015 LFVPICFV 1022 FVP+ FV Sbjct: 1019 FFVPVFFV 1026 Score = 96.1 bits (239), Expect = 4e-22 Identities = 92/506 (18%), Positives = 179/506 (35%), Gaps = 40/506 (7%) Query: 541 FMLVYAGLVAMLGYF-YLRLPEAFVPAEDLGYMVVDVQLP-PGAS-RVRTDATGEELERF 597 F V A ++ M G L+LP A P + V V PGA + D + +E+ Sbjct: 11 FAWVLAIILMMAGALAILQLPVAQYP--TIAPPAVSVSANYPGADAQTVQDTVTQVIEQN 68 Query: 598 LKSREAVASVFLISGFSFSGQGDNAALAFPTFKDWSERGAEQSAAAEIAALNEHFALPDD 657 + + ++ +S S S L F + D A+ ++ LP + Sbjct: 69 MNG---IDNLMYMSSTSDSAGSVTITLTFQSGTD--PDIAQVQVQNKLQLATP--LLPQE 121 Query: 658 GTVMAVSPPPINGLGNSGGFALRLMDRSGVGREALLQARDTLLGEIQTNPKFLYAMMEGL 717 V I+ +S + + S D + +N K + + G+ Sbjct: 122 -----VQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDY----VASNVKDTLSRLNGV 172 Query: 718 AEAP------QLRLLIDREKARALGVSFETISGTLSAA---FGSEVINDFTNAGRQQRVV 768 + +R+ +D + ++ + L + + QQ Sbjct: 173 GDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 769 IQAEQGNRMTPESVLELYVP-NAAGNLVPLSAFVSVKW-EEGPVQLVRYNGYPSIRIVGD 826 Q PE ++ + N+ G++V L V+ E + R NG P+ + Sbjct: 233 SIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 827 AAPGFSTGEA----MAEMERLAAQLPAGIGYEWTGLSYQEKVSAGQATSLFAL--AILVV 880 A G + + A++ L P G+ + V + L AI++V Sbjct: 293 LATGANALDTAKAIKAKLAELQPFFPQGMKVLYP-YDTTPFVQLSIHEVVKTLFEAIMLV 351 Query: 881 FLLLVALYESWSIPLSVMLIVPIGAIGAVLAVMVSGMSNDVYFKVGLITIIGLSAKNAIL 940 FL++ ++ L + VP+ +G + G S + G++ IGL +AI+ Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 941 IVE-FAKELWEQGHSLRDAAIEAARLRFRPIIMTSMAFILGVIPLALASGAGAASQRAIG 999 +VE + + E ++A ++ ++ +M IP+A G+ A R Sbjct: 412 VVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFS 471 Query: 1000 TGVIGGMLSATFLGVLFVPICFVWLL 1025 ++ M + + ++ P LL Sbjct: 472 ITIVSAMALSVLVALILTPALCATLL 497
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.5 bits (100), Expect = 2e-06 Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 4/104 (3%) Query: 99 LKAAVSRAEGELARNRAVLFEAQARVRRYEPLVKIQAVSQQDFDTATADLRSAEAATRSA 158 + A EL ++ L + ++ + + + Q V+Q + LR Sbjct: 257 QENKYVEAVNELRVYKSQLEQIESEILSAK--EEYQLVTQLFKNEILDKLRQTTDNIGLL 314 Query: 159 QADLETARLNLGYASVTAPISGRIGRALV-TEGALVGQGEATLM 201 +L + + AP+S ++ + V TEG +V E TLM Sbjct: 315 TLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAE-TLM 357 Score = 36.3 bits (84), Expect = 2e-04 Identities = 22/199 (11%), Positives = 68/199 (34%), Gaps = 28/199 (14%) Query: 55 PGRIEPV-RVAEVRARVAGIVVQKRFEEGADVKAGDLLFQIDP-------APLKAAVSRA 106 G++ R E++ IV + +EG V+ GD+L ++ ++++ +A Sbjct: 87 NGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQA 146 Query: 107 EGELARNRAVLFEAQARVRRY--------------EPLVKIQAVSQQDFDTATADLRSAE 152 E R + + + E ++++ ++ ++ F T E Sbjct: 147 RLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKE 206 Query: 153 AATRSAQADLETARLNLGYASVTAPISGR---IGRALVTEGALVGQGEATLMARIQQLDP 209 +A+ T + + + +L+ + A+ + ++ + + Sbjct: 207 LNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAI---AKHAVLEQENKYVE 263 Query: 210 IYADFTQTAAEALRLRDAL 228 + ++ ++ + Sbjct: 264 AVNELRVYKSQLEQIESEI 282
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 38.1 bits (88), Expect = 8e-06 Identities = 19/141 (13%), Positives = 52/141 (36%), Gaps = 7/141 (4%) Query: 24 ATLKELAEAAGVSKATLHRFCGTRDNLVQMLEDHGETVLNQIIQACDLEHAEPLEALQRL 83 +L E+A+AAGV++ ++ + +L + + E+ + ++ + ++ R Sbjct: 32 TSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLRE 91 Query: 84 IKEHL-------THRELLVFLVFQYRPDFLDPHGEGARWQSYLEALDAFFLRGQQKGVFR 136 I H+ R LL+ ++F + ++ + + + Sbjct: 92 ILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEA 151 Query: 137 IDITAAVFTELFITLVYGMVD 157 + A + T ++ G + Sbjct: 152 KMLPADLMTRRAAIIMRGYIS 172
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 28.8 bits (64), Expect = 0.048 Identities = 23/85 (27%), Positives = 38/85 (44%), Gaps = 12/85 (14%) Query: 246 AFL-FVDLFDNSGTLIGVAKRAGLMGKDGHMPKMGRALIAD---STAAMGGSLLGTSTTT 301 +FL D F + + ++R +G DG +L+A T A+ SL ST Sbjct: 322 SFLSIADKFKRANKIEEYSQRFKKLGYDGD------SLLAAFHKETGAIDASLTTISTVL 375 Query: 302 SYIESAAGVSAGGRTGLTAIVVAIL 326 + + ++G+SA T L V+ L Sbjct: 376 ASV--SSGISAAATTSLVGAPVSAL 398
>56KDTSANTIGN#Rickettsia 56kDa type-specific antigen protein signature. Length = 533 Score = 30.7 bits (69), Expect = 0.009 Identities = 10/42 (23%), Positives = 26/42 (61%) Query: 246 LANLADNAVDNVSLVRLSAEELTQALNEVRPFRRLADIDLKS 287 LA L++ + S V++ ++++ Q ++++PF +A I++ Sbjct: 247 LAALSNANKPSASPVKVLSDKIIQIYSDIKPFADIAGINVPD 288
>PF06580#Sensor histidine kinase Length = 349 Score = 34.5 bits (79), Expect = 0.002 Identities = 24/93 (25%), Positives = 35/93 (37%), Gaps = 22/93 (23%) Query: 885 SPPGGAIRVRSEASEHTVDLVVEDEGSGIPKAIMDQLFEPFFTTKDPGKGTGLGLALVYS 944 P GG I ++ TV L VE+ GS K+ + TG GL V Sbjct: 275 LPQGGKILLKGTKDNGTVTLEVENTGSLA--------------LKNTKESTGTGLQNVRE 320 Query: 945 IVEEHYG---QITIESPTDHQREGGTRFRVTLP 974 ++ YG QI + ++G V +P Sbjct: 321 RLQMLYGTEAQIKLSE-----KQGKVNAMVLIP 348
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 471 bits (1214), Expect = e-166 Identities = 172/498 (34%), Positives = 261/498 (52%), Gaps = 40/498 (8%) Query: 2 AHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERYTIPSFDMVVSDLRLPGAPGT 61 A IL+ +D+ IR+ L + L R Y V + D+VV+D+ +P Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 ELIK----LAEGIPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVARILKDRQ 117 +L+ +PVL+M++ + +A+ + + GA DY+ KPFD E++ + R L + + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 118 ENRSAAPVSANGGKAGGERGASPAAADGEIGIIGSCAPMQELYSKIRKVAPTDSTVLIQG 177 S + G ++G A MQE+Y + ++ TD T++I G Sbjct: 124 RRPSKLEDDSQDGM----------------PLVGRSAAMQEIYRVLARLMQTDLTLMITG 167 Query: 178 ESGTGKELVARALHNLSKRAKAPLISVNCAAIPETLIESELFGHEKGAFTGASAGRAGLV 237 ESGTGKELVARALH+ KR P +++N AAIP LIESELFGHEKGAFTGA G Sbjct: 168 ESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRF 227 Query: 238 EAADGGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKTLA 297 E A+GGTLFLDEIG++P++AQ RLLRVLQ+GE VG + DVR++AAT++DLK Sbjct: 228 EQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSI 287 Query: 298 KTGQFREDLYYRLHVISLKLPALRERGNDVMEIARAFLARQCTRMGRAPLSFAHDAEQAI 357 G FREDLYYRL+V+ L+LP LR+R D+ ++ R F+ + + G F +A + + Sbjct: 288 NQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQAE-KEGLDVKRFDQEALELM 346 Query: 358 RHYPWPGNVRELENAIERAVILSESQEIHADLLGIDIELDDLEDDFAADLGLGPAGAAAS 417 + +PWPGNVRELEN + R L I +++ ++ + + + + + Sbjct: 347 KAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQ 406 Query: 418 NHE---------PTEDLSLEDYFQHFVLEHQDHMTETEL----------ARKLGISRKCL 458 E + L + + E + + L A LG++R L Sbjct: 407 AVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTL 466 Query: 459 WERRQRLGIPRRKSGASA 476 ++ + LG+ +S SA Sbjct: 467 RKKIRELGVSVYRSSRSA 484
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 76.8 bits (189), Expect = 2e-18 Identities = 33/123 (26%), Positives = 57/123 (46%), Gaps = 1/123 (0%) Query: 2 RILLAEDDLLLGDGIRAGLRLEGDTVEWVTDGVAAENALVTDEFDLLVLDIGLPRRSGLD 61 IL+A+DD + + L G V ++ + + DL+V D+ +P + D Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 62 ILRNLRHQGRLTPVLLLTARDKVADRVAGLDSGADDYLTKPFYLDELQARV-RALTRRTT 120 +L ++ PVL+++A++ + + GA DYL KPF L EL + RAL Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 121 GRA 123 + Sbjct: 125 RPS 127
>PF06580#Sensor histidine kinase Length = 349 Score = 33.7 bits (77), Expect = 0.002 Identities = 15/81 (18%), Positives = 31/81 (38%), Gaps = 20/81 (24%) Query: 360 LVGNALRY----TPAGGQVEIRVENRAQHAVLRVRDNGPGVALEEQQAIFTRFYRSPATS 415 LV N +++ P GG++ ++ L V + G + Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLA----------------LKN 306 Query: 416 SGEGSGLGLPIVKRIVELHFG 436 + E +G GL V+ +++ +G Sbjct: 307 TKESTGTGLQNVRERLQMLYG 327
>PF07675#Cleaved Adhesin Length = 1358 Score = 30.4 bits (68), Expect = 0.002 Identities = 17/82 (20%), Positives = 35/82 (42%), Gaps = 2/82 (2%) Query: 3 IGEAAKKSGLTPKMIRYYESIELLRPAGRSASGYRHYNENDLHTLAFIRRSRDLGFSLDE 62 G + + +G P+ + +++L PAG +RHYN +DL+ + +G S Sbjct: 933 FGLSTEANGAKPQSVWIERTVDL--PAGTKYVAFRHYNCSDLNYILLDDIQFTMGGSPTP 990 Query: 63 VGKLLTLWQDRQRASADVKALA 84 T+++D + + Sbjct: 991 TDYTYTVYRDGTKIKEGLTETT 1012
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 30.8 bits (69), Expect = 0.008 Identities = 15/75 (20%), Positives = 28/75 (37%), Gaps = 4/75 (5%) Query: 218 PELRQTRYAKEMWALYEAGELTAETPLSGTFVEAEEAADVRAVLREIEAAQREEARRQAL 277 + AKE + +A T E SG+ E +E +E ++EE + Sbjct: 1061 TTAQNREVAKEAKSNVKANTQTNEVAQSGS--ETKETQ--TTETKETATVEKEEKAKVET 1116 Query: 278 RQADDAPRGEREEPP 292 + + P+ + P Sbjct: 1117 EKTQEVPKVTSQVSP 1131
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 73.3 bits (180), Expect = 2e-16 Identities = 29/120 (24%), Positives = 52/120 (43%), Gaps = 6/120 (5%) Query: 13 LLVVDDTPDNLLLMRELLE-EQYRVRTAGSGPAGLRAAVEEPRPDLILLDVNMPGMDGYE 71 +LV DD ++ + L Y VR + R + DL++ DV MP + ++ Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRW-IAAGDGDLVVTDVVMPDENAFD 64 Query: 72 VCRRLKA-DPLTRDIPLMFLTARADRDDEQQGLALGAVDYLGKPVSPPIVLARVRTHLQL 130 + R+K P D+P++ ++A+ + GA DYL KP ++ + L Sbjct: 65 LLPRIKKARP---DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAE 121
>PF05272#Virulence-associated E family protein Length = 892 Score = 27.7 bits (61), Expect = 0.044 Identities = 13/37 (35%), Positives = 19/37 (51%) Query: 14 SHILRGLSFEAKVGEVTCLLGRNGVGKTTLLRCLMGL 50 H+ R + K L G G+GK+TL+ L+GL Sbjct: 583 GHVARVMEPGCKFDYSVVLEGTGGIGKSTLINTLVGL 619
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 36.5 bits (84), Expect = 1e-05 Identities = 16/74 (21%), Positives = 34/74 (45%), Gaps = 1/74 (1%) Query: 57 DGQPVGLLVTRETADGFL-VDNLAVLPECKGQGIGRQLLERAERDATSLGYRSLYLYTNE 115 + +G + R +G+ ++++AV + + +G+G LL +A A + L L T + Sbjct: 73 ENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQD 132 Query: 116 RMTENIALYARVGY 129 YA+ + Sbjct: 133 INISACHFYAKHHF 146
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 41.9 bits (98), Expect = 2e-07 Identities = 15/63 (23%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 81 RGTVEHSVYVRDDQRGKGLGVQLLQALIERARAQGLHVMVAAIESGNAASIGLHRRLGFE 140 +E + V D R KG+G LL IE A+ ++ + N ++ + + F Sbjct: 89 YALIED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 141 ISG 143 I Sbjct: 148 IGA 150
>UREASE#Urea amidohydrolase (urease) protein signature. Length = 570 Score = 1096 bits (2837), Expect = 0.0 Identities = 423/567 (74%), Positives = 479/567 (84%), Gaps = 2/567 (0%) Query: 2 KISRQAYADMFGPTVGDRVRLADTDLWIEVERDFTVYGEEVKFGGGKVIRDGMGQSQL-G 60 ++SR AYA+MFGPTVGD+VRLADT+L+IEVE+DFT +GEEVKFGGGKVIRDGMGQSQ+ Sbjct: 4 RMSRAAYANMFGPTVGDKVRLADTELFIEVEKDFTTHGEEVKFGGGKVIRDGMGQSQVTR 63 Query: 61 AAQVVDTVITNALILDHWGVVKADVGLKDGRIQAIGKAGNPDIQPGVNIAIGAGTEVIAG 120 VDTVITNALILDHWG+VKAD+GLKDGRI AIGKAGNPD+QPGV I +G GTEVIAG Sbjct: 64 EGGAVDTVITNALILDHWGIVKADIGLKDGRIAAIGKAGNPDMQPGVTIIVGPGTEVIAG 123 Query: 121 EGMILTAGGIDTHIHFICPQQIEEALMSGVTTMIGGGTGPAAGTNATTCTSGPWHMARML 180 EG I+TAGG+D+HIHFICPQQIEEALMSG+T M+GGGTGPA GT ATTCT GPWH+ARM+ Sbjct: 124 EGKIVTAGGMDSHIHFICPQQIEEALMSGLTCMLGGGTGPAHGTLATTCTPGPWHIARMI 183 Query: 181 QAADAFPMNIGFTGKGNASLPLPLEEQVLAGAIGLKLHEDWGSTPAAIDNCLEVAERHDI 240 +AADAFPMN+ F GKGNASLP L E VL GA LKLHEDWG+TPAAID CL VA+ +D+ Sbjct: 184 EAADAFPMNLAFAGKGNASLPGALVEMVLGGATSLKLHEDWGTTPAAIDCCLSVADEYDV 243 Query: 241 QVAIHTDTLNESGFVETTLGAFKGRTIHTYHTEGAGGGHAPDIIKACGFANVLPSSTNPT 300 QV IHTDTLNESGFVE T+ A KGRTIH YHTEGAGGGHAPDII+ CG NV+PSSTNPT Sbjct: 244 QVMIHTDTLNESGFVEDTIAAIKGRTIHAYHTEGAGGGHAPDIIRICGQPNVIPSSTNPT 303 Query: 301 RPFTRNTIDEHLDMLMVCHHLDPAIAEDVAFAESRIRRETIAAEDILHDLGAFSMISSDS 360 RP+T NT+ EHLDMLMVCHHL P I ED+AFAESRIR+ETIAAEDILHD+GAFS+ISSDS Sbjct: 304 RPYTVNTLAEHLDMLMVCHHLSPTIPEDIAFAESRIRKETIAAEDILHDIGAFSIISSDS 363 Query: 361 QAMGRVGEVITRTWQTADKMKRQRGRLDGDGARNDNFRARRYIAKYTINPAITHGISHEV 420 QAMGRVGEV RTWQTADKMKRQRGRL + NDNFR +RYIAKYTINPAI HG+SHE+ Sbjct: 364 QAMGRVGEVAIRTWQTADKMKRQRGRLKEETGDNDNFRVKRYIAKYTINPAIAHGLSHEI 423 Query: 421 GSVEAGKWADLVLWRPAFFGVKPSLILKGGAIAASLMGDINGSIPTPQPVHYRPMFASYA 480 GS+E GK ADLVLW PAFFGVKP ++L GG IAA+ MGD N SIPTPQPVHYRPMF +Y Sbjct: 424 GSLEVGKRADLVLWNPAFFGVKPDMVLLGGTIAAAPMGDPNASIPTPQPVHYRPMFGAYG 483 Query: 481 GSRHATSLTFVSQAAFAAGVPQQLGLRKAIGVVSGCR-GVQKTDLIHNGYLPTIEVDAQN 539 SR +S+TFVSQA+ AG+ +LG+ K + V R G+ K +IHN P IEVD + Sbjct: 484 RSRTNSSVTFVSQASLDAGLAGRLGVAKELVAVQNTRGGIGKASMIHNSLTPHIEVDPET 543 Query: 540 YQVRADGQLLWCEPADVLPMAQRYFLF 566 Y+VRADG+LL CEPA VLPMAQRYFLF Sbjct: 544 YEVRADGELLTCEPATVLPMAQRYFLF 570
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 44.6 bits (105), Expect = 4e-07 Identities = 22/104 (21%), Positives = 30/104 (28%), Gaps = 3/104 (2%) Query: 355 LPSAAVPPTVSSSAPPVTPLANNGVTPMHPVPPAPTEPTAPAATP---TPAQTPAPAAPV 411 LP+ A P +V+ AP P PV EP P P Sbjct: 43 LPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK 102 Query: 412 ASAPASKPAPAPAKPAASKPATTAAAKPAPAPAAKPASGGGAGS 455 K P + + A+ APA +S A + Sbjct: 103 PKPKPVKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAAT 146 Score = 42.7 bits (100), Expect = 2e-06 Identities = 16/99 (16%), Positives = 23/99 (23%) Query: 355 LPSAAVPPTVSSSAPPVTPLANNGVTPMHPVPPAPTEPTAPAATPTPAQTPAPAAPVASA 414 + A + P + PP + P PP P P P P V Sbjct: 55 VAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQP 114 Query: 415 PASKPAPAPAKPAASKPATTAAAKPAPAPAAKPASGGGA 453 + + A + A AA Sbjct: 115 KRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSV 153 Score = 33.4 bits (76), Expect = 0.002 Identities = 23/70 (32%), Positives = 24/70 (34%), Gaps = 9/70 (12%) Query: 383 HPVPPAPTEP-----TAPAATPTPAQTPAPAAPVASAPASKPAPAPAKPAASKPATTAAA 437 PAP +P APA P P PV P P P P K A Sbjct: 40 VIELPAPAQPISVTMVAPADLEPPQAVQPPPEPVVEPE---PEPEPI-PEPPKEAPVVIE 95 Query: 438 KPAPAPAAKP 447 KP P P KP Sbjct: 96 KPKPKPKPKP 105
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.9 bits (64), Expect = 0.011 Identities = 11/33 (33%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 4 LILVGPMGAGKSTIGRLLAKELHLAFKDSDKEI 36 ++L G G GKST+ L F D+ +I Sbjct: 599 VVLEGTGGIGKSTLINTLVGLDF--FSDTHFDI 629
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 312 bits (800), Expect = 1e-98 Identities = 110/419 (26%), Positives = 183/419 (43%), Gaps = 53/419 (12%) Query: 325 VPWDQALDLVLKTKGLDKRKLGNVLLVAPADEIAARERQEL--------EAQKQIAELAP 376 + W A D+V L+K + L + + A ER Q+ IA + Sbjct: 199 LSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSRQRIIAMIKQ 258 Query: 377 LRRE--------LIQVNYAKAADIAKLFQSVTSDGGQEGKEGGRGS--------ITVDDR 420 L R+ +I + YAKA+D+ ++ + S Q K+ + I + Sbjct: 259 LDRQQATQGNTKVIYLKYAKASDLVEVLTGI-SSTMQSEKQAAKPVAALDKNIIIKAHGQ 317 Query: 421 TNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEARIVEANVGYDKSLGVRWGGAYHKGNW 480 TN++I + +++L R+++QLDI QV++EA I E +LG++W Sbjct: 318 TNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWANKN----- 372 Query: 481 RGYGKDGNIGIKDEDGMNCGPIAGNCTFPTTGTSKSPSPFVDIGAKDATSGIGIGFITDN 540 G + N G+ + AG + GT S A + +GI GF N Sbjct: 373 AGMTQFTNSGLPISTAI-----AGANQYNKDGTVSSSLA----SALSSFNGIAAGFYQGN 423 Query: 541 IILDLQLSAMEKTGNGEIVSQPKVVTSDKETAKILKGQEVPYQEASSSGATSTSF----- 595 + L+A+ + +I++ P +VT D A GQEVP S + + F Sbjct: 424 --WAMLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGDNIFNTVER 481 Query: 596 KEAALSLEVTPQITPDNRIIVEVK-----VTKDAPDFDRALNGVPPINKNEVNAKILVND 650 K + L+V PQI + +++E++ V A L N VN +LV Sbjct: 482 KTVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGAT--FNTRTVNNAVLVGS 539 Query: 651 GETIVIGGVFSNTQSKSVDKVPFLGDLPYLGRLFRRDTVSDVKNELLVFLTPRIMNNQA 709 GET+V+GG+ + S + DKVP LGD+P +G LFR + K L++F+ P ++ ++ Sbjct: 540 GETVVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRD 598 Score = 52.6 bits (126), Expect = 4e-09 Identities = 31/188 (16%), Positives = 74/188 (39%), Gaps = 13/188 (6%) Query: 281 GEKLSLNFQDIDVRSVLQLIADFTDLNLVASDTVQGNITLRLQN-VPWDQALDL---VLK 336 E+ S +F+ D++ + ++ + ++ +V+G IT+R + + +Q VL Sbjct: 27 AEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSYDMLNEEQYYQFFLSVLD 86 Query: 337 TKGLDKRKLGN-VLLVAPADEIAARERQELEAQKQIAELAPLRRELIQVNYAKAADIAKL 395 G + N VL V + + A + + + ++ + A D+A L Sbjct: 87 VYGFAVINMNNGVLKVVRSKD-AKTAAVPVASDAAPGIGDEVVTRVVPLTNVAARDLAPL 145 Query: 396 FQSVTSDGGQEGKEGGRGSITVDDRTNSIIAYQPQERLDELRRIVSQLDIPVRQVMIEAR 455 + + + G GS+ + +N ++ + L IV ++D + ++ Sbjct: 146 LRQLNDN-------AGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNAGDRSVVTVP 198 Query: 456 IVEANVGY 463 + A+ Sbjct: 199 LSWASAAD 206
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 32.4 bits (74), Expect = 0.002 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 38/158 (24%) Query: 197 VVDIGATMTTLSVLHNGRTIYTREQLFGGRQLTEEI----QRRYGLSVEE--AGLAKKQG 250 VVDIG T ++V+ +Y+ GG + E I +R YG + E A K + Sbjct: 163 VVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEI 222 Query: 251 G--LPDDYDSEV-------------------------LRPFKDAVVQQVSRSLQFF---F 280 G P D E+ L+ +V V +L+ Sbjct: 223 GSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPEL 282 Query: 281 AAGQFNDVDYIVLAGGTASIQDLDRLIQQKIGTPTLVA 318 A+ +VL GG A +++LDRL+ ++ G P +VA Sbjct: 283 ASDISER--GMVLTGGGALLRNLDRLLMEETGIPVVVA 318
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.001 Identities = 27/213 (12%), Positives = 50/213 (23%), Gaps = 26/213 (12%) Query: 79 EALQGTPDLQIAEARARQAAATAQAQDAARQPTLDAKASYSGIRAPTSVAPAPLGGRYSA 138 AL D ++ QA + K + Sbjct: 128 TALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRL 187 Query: 139 IKYLSLGFNYDFDLWGGERAAWEAALGQANAARIDSQAARIGLSASIARAYSDLAHAFTV 198 F W ++ E L + A R+ A S L ++ Sbjct: 188 TSL----IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSL 243 Query: 199 RD--------LAEEELKRSQRMTELSQKR------MSAGLDSKVQLQQ--------TQTQ 236 + E+E K + + EL + S L +K + Q + Sbjct: 244 LHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK 303 Query: 237 LATARQQLSAAEQDIASARIALAVLLGKGPDRG 269 L + ++A + + P Sbjct: 304 LRQTTDNIGLLTLELAKNEERQQASVIRAPVSV 336
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 76.8 bits (189), Expect = 2e-17 Identities = 47/368 (12%), Positives = 105/368 (28%), Gaps = 90/368 (24%) Query: 54 GNVVQITPQIVGTVVSIGADDGDLVRKGQELVRFDPSDADIALQRAEANLA--------- 104 G +I P V I +G+ VRKG L++ A+ + +++L Sbjct: 94 GRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRY 153 Query: 105 -----------------------------HTVRQVRGLFSNVDGYRAEVATRKVALAKAE 135 +R + ++ + +++ L K Sbjct: 154 QILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKR 213 Query: 136 ADYK----RRKNLADDGAISQEELAH----------ARDALDSAKASLTSSEQQLNTNRA 181 A+ R + + + L A+ A+ + + +L ++ Sbjct: 214 AERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKS 273 Query: 182 LVDDTQ---------------------ITSHPDVKAAAAQLRQ----AYLDDARSTIVAP 216 ++ + + L S I AP Sbjct: 274 QLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAP 333 Query: 217 VTGYVAKRSVQ-VGQRVQPGTALMAVVPLDQ-IWIDANFKETQLKHMRIGQPVEIRSDLY 274 V+ V + V G V LM +VP D + + A + + + +GQ I+ + + Sbjct: 334 VSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF 393 Query: 275 GSDV--RYSGTVDSLGVGTGSAFSLLPAQNATGNWIKIVQRVPVRIHIDPQELQKHPLRI 332 G V ++ + G ++ + + + PL Sbjct: 394 PYTRYGYLVGKVKNINLDA-------IEDQRLGLVFNVIISIEE--NCLSTGNKNIPLSS 444 Query: 333 GLSMDVKV 340 G+++ ++ Sbjct: 445 GMAVTAEI 452
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 109 bits (275), Expect = 5e-28 Identities = 74/397 (18%), Positives = 155/397 (39%), Gaps = 16/397 (4%) Query: 17 IGLSLATFMQVLDTTIANVALPTISGNLGVSSEQGTWVITSFAVSNAIALPLTGWLARRV 76 I L + +F VL+ + NV+LP I+ + WV T+F ++ +I + G L+ ++ Sbjct: 17 IWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQL 76 Query: 77 GEVRLFIAAALLFVLASFLCGIAQSMPSLVGFRALQGFVAGPLYPITQTLLISIY-PPAK 135 G RL + ++ S + + S SL+ +P ++++ Y P Sbjct: 77 GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKEN 136 Query: 136 RGMALALLAMVTVVAPIAGPILGGWITDDYSWPWIFFINVPVGLFAAFVVYQQLKARPVV 195 RG A L+ + + GP +GG I W ++ I + + F++ + V Sbjct: 137 RGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLL---KKEV 193 Query: 196 IKKAPMDYVGLIALVIGVGALQIVLDKGNDLDWFESNFIVGGALIAAIALAFFIIWEFTD 255 K D G+I + +G+ + F +++ + +++ ++ F+ Sbjct: 194 RIKGHFDIKGIILMSVGIVFFML----------FTTSYSISFLIVSVLSFLIFVKHIRKV 243 Query: 256 RHPIVNLRLFAHRNFAAGTLALVLGYAAFFGINLLLPQWLQTQMGYTATWAGLAAAPIGI 315 P V+ L + F G L + + G ++P ++ + G G Sbjct: 244 TDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGT 303 Query: 316 LPV-FLSPLVGRYANHFDLRMLAGLSFLAMAITCFMRANFTTEVDYQHIAIVQLIMGLGV 374 + V + G + + + ++++ F+ A+F E + I+ + + G+ Sbjct: 304 MSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVS-FLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 375 AFFFMPILSILLSDLPPDQIADGSGLATFLRTLGGSF 411 +F I +I+ S L + G L F L Sbjct: 363 SFTKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGT 399
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 177 bits (450), Expect = 6e-55 Identities = 86/352 (24%), Positives = 136/352 (38%), Gaps = 42/352 (11%) Query: 1 MTILVTGSAGFIGANFVLDWLALHDEPVVSLDKLT--YAGNRQNL-ASLDGNARHTFVAG 57 M LVTG+AGFIG + L + VV +D L Y + + L F Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQ-VVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 58 DIGDSQLVARLLAEHQPRAILNFAAESHVDRSIHGPEDFIQTNIVGTFRLLEEVRAYWGA 117 D+ D + + L A + V S+ P + +N+ G +LE R Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN--- 116 Query: 118 LEPEAKAAFRFLHVSTDEVYGSLAPSDPAFTENNRYEPNSPYSASKAASDHLVRAYHHTY 177 + + L+ S+ VYG L P T+++ P S Y+A+K A++ + Y H Y Sbjct: 117 -KIQ-----HLLYASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLY 169 Query: 178 GLPVLTTNCSNNYGPYHFPEKLIPLVIHNALAGKPLPIYGDGQQIRDWLYVKDHCSAIRR 237 GLP YGP+ P+ + L GK + +Y G+ RD+ Y+ D AI R Sbjct: 170 GLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 238 VLEAGQL------------------GETYNVGGWNEKANLDVVETLCAILDQEQPRADGR 279 + + YN+G + +D ++ L L E A Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIE---AK-- 284 Query: 280 SYREQITFVKDRPGHDRRYAIDATRLERELGWKPAETFETGIRKTVRWYLDN 331 + +PG + D L +G+ P T + G++ V WY D Sbjct: 285 -----KNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 46.3 bits (110), Expect = 5e-08 Identities = 32/158 (20%), Positives = 55/158 (34%), Gaps = 27/158 (17%) Query: 3 RILLLGANGQVGWELQRALAPLGE--------------LLVCDRR-----------RADL 37 + L+ GA G +G+ + + L G L R + DL Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 38 ADPEGLARLVRAERPQFIVNAGAYTAVDKAESDADNARLINARAVAVLAEEAAGCG-AWL 96 AD EG+ L + + + + AV + + N + E L Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 97 VHYSTDYVFDGAGSVPFAEDAPTG-PLSVYGQTKLEGE 133 ++ S+ V+ +PF+ D P+S+Y TK E Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANE 159
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 446 bits (1150), Expect = e-156 Identities = 176/480 (36%), Positives = 240/480 (50%), Gaps = 48/480 (10%) Query: 11 TQVLLIDDDPHLRQALRQTLDLAGLKVATLDDARQLDTAQCKDWPGVVVSDIRMPGIDGM 70 +L+ DDD +R L Q L AG V +A L +VV+D+ MP + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 71 ELLRQLHEQDADLPVILITGHGDVPLAVQAMRGGAYDFLEKPFPSDALLDSVRRALEVRR 130 +LL ++ + DLPV++++ A++A GAYD+L KPF L+ + RAL + Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 131 LVLENRTLRLALAERHELHGRLIGRSAGMQRLREQVGSLAAIQADVLVLGETGAGKEVVA 190 R + + L+GRSA MQ + + L +++ GE+G GKE+VA Sbjct: 124 -----RRPSKLEDDSQDGMP-LVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVA 177 Query: 191 RALHDLSSRRDGPFVAINAGALAESVVESELFGHEAGAFTGAQKRRIGKFEYANGGTLFL 250 RALHD RR+GPFVAIN A+ ++ESELFGHE GAFTGAQ R G+FE A GGTLFL Sbjct: 178 RALHDYGKRRNGPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFL 237 Query: 251 DEIESMSLDVQVKLLRLLQERVVERLGSNQLIPLDIRIIAATKEDLRQAADQGRFRADLY 310 DEI M +D Q +LLR+LQ+ +G I D+RI+AAT +DL+Q+ +QG FR DLY Sbjct: 238 DEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLY 297 Query: 311 YRLNVASLRIPPLRERGEDIPLLFRHFAEAGAMRHGLTPRELDAGQSARLLAYDWPGNVR 370 YRLNV LR+PPLR+R EDIP L RHF + A + GL + D + A+ WPGNVR Sbjct: 298 YRLNVVPLRLPPLRDRAEDIPDLVRHFVQQ-AEKEGLDVKRFDQEALELMKAHPWPGNVR 356 Query: 371 ELQNAAERFAL-----------------------------------------GLGLSLDD 389 EL+N R + Sbjct: 357 ELENLVRRLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYF 416 Query: 390 GVLPDAADEPHNLSAKVEAFERSLIAAELERPHNSLRSVAEALGIPRKTLHDKLRKHGLP 449 DA + E LI A L + A+ LG+ R TL K+R+ G+ Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGVS 476
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 25.5 bits (56), Expect = 0.048 Identities = 10/34 (29%), Positives = 15/34 (44%), Gaps = 2/34 (5%) Query: 8 PARPGHWPRPGTILYSCPITPIPKREPMEDADLQ 41 P W RPG ILY +P + + + L+ Sbjct: 199 PEAHFDWVRPGIILYG--ASPSGQWRDIANTGLR 230
>ABC2TRNSPORT#ABC-2 type transport system membrane protein signature. Length = 262 Score = 44.2 bits (104), Expect = 4e-07 Identities = 41/174 (23%), Positives = 67/174 (38%), Gaps = 4/174 (2%) Query: 196 AALIREREHGTVEHLLVMPLSAFEIMMAKV-WSMGLVVLVAAGLSLQWVVRGWLDVPISG 254 AA R T E +L L +I++ ++ W+ L AG+ + G+ Sbjct: 89 AAFGRMEGQRTWEAMLYTQLRLGDIVLGEMAWAATKAALAGAGIGVVAAALGYTQWL--- 145 Query: 255 SVGLFLLGAGLHLFATTSMGIFLGTVARSMPQLGLLTILVLLPLNILSGGTTPRESMPEL 314 S+ L L A S+G+ + +A S LV+ P+ LSG P + +P + Sbjct: 146 SLLYALPVIALTGLAFASLGMVVTALAPSYDYFIFYQTLVITPILFLSGAVFPVDQLPIV 205 Query: 315 VQNIMLAAPTTHFVSLAQAILFRGAGFDIVWPQFAGIVVIGSAFFFGALWRFRR 368 Q P +H + L + I+ D+ A + I FF RR Sbjct: 206 FQTAARFLPLSHSIDLIRPIMLGHPVVDVCQHVGALCIYIVIPFFLSTALLRRR 259
>PF05272#Virulence-associated E family protein Length = 892 Score = 32.0 bits (72), Expect = 0.013 Identities = 13/39 (33%), Positives = 17/39 (43%), Gaps = 2/39 (5%) Query: 36 MVGLIGPDGVGKSSLLALLAGARKMQDGEIRVLDGDMRD 74 V L G G+GKS+L+ L G D G +D Sbjct: 598 SVVLEGTGGIGKSTLINTLVGLDFFSDTHF--DIGTGKD 634
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 80.6 bits (199), Expect = 7e-19 Identities = 59/392 (15%), Positives = 126/392 (32%), Gaps = 85/392 (21%) Query: 1 MKQESKRWLSRALVVAALLGVGVLVWQVSRPTGLGEGFASGNGRI--EATEVDVAAKLPG 58 ++ R V + V E A+ NG++ ++ Sbjct: 49 IETPVSRRPRLVAYFIMGFLVIAFILSVLGQV---EIVATANGKLTHSGRSKEIKPIENS 105 Query: 59 RVAEIKVDEGDFVKAGEIVARMDTQVLEAQLAQAQAQVRQAENAKLTATSLVAQRESEKS 118 V EI V EG+ V+ G+++ ++ EA + Q+ + QA + L E K Sbjct: 106 IVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKL 165 Query: 119 TAQAVVAQRQAELTAAQKRFTRTEALVKRNALPQQQLDDDRATLQSAQAALSAARSQV-- 176 + + + + ++ T + ++ + Q Q L +A +++ Sbjct: 166 PELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINR 225 Query: 177 ------------------------------------ISAQAAIEAGRSQVIEAQSAIEAA 200 + A + +SQ+ + +S I +A Sbjct: 226 YENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSA 285 Query: 201 KASVARLQADIDD-----------------------------SLLKAPRNGRV-QYRVAQ 230 K + + S+++AP + +V Q +V Sbjct: 286 KEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHT 345 Query: 231 PGEVLPAGGKLLNMVDLADVY-MTFFLPSMQAGRVGLGQEVRLVIDAVPDY---VIPAKV 286 G V+ L+ +V D +T + + G + +GQ + ++A P + KV Sbjct: 346 EGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKV 405 Query: 287 SYVASVAQFTPKTVETANEREKLMFRVKARLD 318 + +E ++R L+F V ++ Sbjct: 406 KNIN------LDAIE--DQRLGLVFNVIISIE 429
>CARBMTKINASE#Bacterial carbamate kinase signature. Length = 314 Score = 54.8 bits (132), Expect = 8e-11 Identities = 66/301 (21%), Positives = 116/301 (38%), Gaps = 61/301 (20%) Query: 26 VGKTLVIKYGGNAMESEELKAGF----------ARDVVLMKAVGINPVVVHGGGPQIGDL 75 +GK +VI GGNA++ K + AR + + A G V+ HG GPQ+G L Sbjct: 1 MGKRVVIALGGNALQQRGQKGSYEEMMDNVRKTARQIAEIIARGYEVVITHGNGPQVGSL 60 Query: 76 LKRLSIESHFIDGMRVTDAATMDVV-----------------EMVLGGQVNKDIVNLINR 118 L L +++ A MDV + + K +V +I + Sbjct: 61 L--LHMDAG--QATYGIPAQPMDVAGAMSQGWIGYMIQQALKNELRKRGMEKKVVTIITQ 116 Query: 119 -----------HGGSAIG--LTGKDAELIRAKKLTVTRQ---------TPEMTKPEIIDI 156 + +G + A+ + +K + ++ P ++ Sbjct: 117 TIVDKNDPAFQNPTKPVGPFYDEETAKRLAREKGWIVKEDSGRGWRRVVPSPDPKGHVEA 176 Query: 157 GHVGEVTGVNVGLLNMLVKGDFIPVIAPIGVGSNGESYNINADLVAGKVAEALKAEKLML 216 + V G++ + G +PVI G E+ I+ DL K+AE + A+ M+ Sbjct: 177 ETIK--KLVERGVIVIASGGGGVPVILEDGEIKGVEAV-IDKDLAGEKLAEEVNADIFMI 233 Query: 217 LTNIAGLMDKQG----QVLTGLSTEQVNELIADGT-IYGGMLPKIRCALEAVQGGVTSAH 271 LT++ G G Q L + E++ + +G G M PK+ A+ ++ G A Sbjct: 234 LTDVNGAALYYGTEKEQWLREVKVEELRKYYEEGHFKAGSMGPKVLAAIRFIEWGGERAI 293 Query: 272 I 272 I Sbjct: 294 I 294
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 29.0 bits (65), Expect = 0.029 Identities = 19/136 (13%), Positives = 41/136 (30%), Gaps = 18/136 (13%) Query: 161 RALVSPAFEPLGIELIHAAPPYAGEYLRLLGPQVRFGCLHNRMAIASHWLDMRLPNHNLP 220 R + + E+I + R G L A+ + R + Sbjct: 364 RLTALYPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENM---RQYFASFG 420 Query: 221 ALRQALALLEQESTQVHRKLDLVQAVERAIARDLSLGSQIERISAELNMSSRTLRRRLAE 280 L ++ ++ L ++ A+ + + L ++ TLR+++ E Sbjct: 421 DALPPSGLYDRVLAEMEYPL-ILAALTAT-------RGNQIKAADLLGLNRNTLRKKIRE 472 Query: 281 HGLTFEALLEQVRRGR 296 G+ V R Sbjct: 473 LGV-------SVYRSS 481
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 28.6 bits (64), Expect = 0.040 Identities = 26/147 (17%), Positives = 49/147 (33%), Gaps = 21/147 (14%) Query: 33 IDLDRLDHNIDVVMRSVRRGGKHLRL--VEKSLPSPGLLAYIARRAGTRRLMSFHQPFLN 90 +DL L N+ VR+ H R+ V K+ + I G Sbjct: 9 LDLQALKQNL----SIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGF-------- 56 Query: 91 HDAVAFADADILL---GKPLPVRSAELFYREHKGAFDPARQLQWLIDTPQRLRQYLALAQ 147 A+ + I L G P+ E F+ +L + + +L+ Sbjct: 57 --ALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNAR- 113 Query: 148 GLGTRMRVNIELDVGLHRGGVADQAAL 174 L + + ++++ G++R G L Sbjct: 114 -LKAPLDIYLKVNSGMNRLGFQPDRVL 139
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.8 bits (67), Expect = 0.008 Identities = 17/109 (15%), Positives = 36/109 (33%), Gaps = 1/109 (0%) Query: 82 LRQRKAAQAQASSDAQLLRLYSSLEDVDRARERRLAELDGLSSVARGNLQSLKLQQANLQ 141 L + + + + L +SSL + + E + A L+ K Q ++ Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279 Query: 142 GQAAN-QERAGRPVAQALVDQLDDLKQEEKRLQGEIGRFQKAREDAERT 189 + + +E + LD L+Q + K E + + Sbjct: 280 SEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQAS 328
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 27.9 bits (62), Expect = 0.040 Identities = 12/46 (26%), Positives = 23/46 (50%) Query: 105 HGEGGTLVGAPLSGRVLIIDDVITAGTAIREVMQIIDAQGARAAGV 150 H + + +SG VL + +T G + + + ++ A GA+ A V Sbjct: 686 HSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKV 731
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 28.3 bits (63), Expect = 0.009 Identities = 7/41 (17%), Positives = 18/41 (43%) Query: 65 FQITVALAMFVSFLLMLVVIGFFLLGLVCLAALVLTIIAGI 105 VA++ V FL + + + + + + + L I+ + Sbjct: 872 APALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVL 912
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 99.5 bits (248), Expect = 2e-26 Identities = 39/124 (31%), Positives = 63/124 (50%), Gaps = 2/124 (1%) Query: 1 MVGKTILIVDDEAPIREMIAVALEMAGYECLEAENTQQAHAVIVDRKPDLILLDWMLPGT 60 M G TIL+ DD+A IR ++ AL AGY+ N I DL++ D ++P Sbjct: 1 MTGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE 60 Query: 61 SGIELARRLKRDELTVDIPIIMLTAKGEEDNKIQGLEVGADDYITKPFSPRELVARLKAV 120 + +L R+K+ D+P+++++A+ I+ E GA DY+ KPF EL+ + Sbjct: 61 NAFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRA 118 Query: 121 LRRT 124 L Sbjct: 119 LAEP 122
>PF06580#Sensor histidine kinase Length = 349 Score = 37.9 bits (88), Expect = 6e-05 Identities = 22/99 (22%), Positives = 36/99 (36%), Gaps = 25/99 (25%) Query: 333 LVFNAVKY----TPDEGEIRIRWWADEQGAHLSVQDTGIGVDPKHLPRLTERFYRVDSSR 388 LV N +K+ P G+I ++ D L V++TG Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALK----------------- 305 Query: 389 ASNTGGTGLGLAIVKHVLIR---HRARLEISSVPGKGST 424 + TG GL V+ L A++++S GK + Sbjct: 306 -NTKESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA 343
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 91.4 bits (227), Expect = 8e-23 Identities = 29/139 (20%), Positives = 63/139 (45%), Gaps = 4/139 (2%) Query: 1 MSKVSALVVDDAPFIRDLMKKGLRDNFPGLHIEEAVNGRKAQQLLSRQNVDLILCDWEMP 60 M+ + LV DD IR ++ + L + G + N + ++ + DL++ D MP Sbjct: 1 MTGATILVADDDAAIRTVLNQAL--SRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMP 58 Query: 61 EMSGLELLTWCRAQENLKTTPFIMVTSRGDKENVVQAIQAGVSDYIGKPFSNDQLVAKIK 120 + + +LL + P ++++++ ++A + G DY+ KPF +L+ I Sbjct: 59 DENAFDLLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116 Query: 121 KALSRSGKLEALAAHAPRR 139 +AL+ + + + Sbjct: 117 RALAEPKRRPSKLEDDSQD 135
>FLGHOOKAP1#Flagellar hook-associated protein signature. Length = 546 Score = 28.4 bits (63), Expect = 0.033 Identities = 22/88 (25%), Positives = 41/88 (46%), Gaps = 9/88 (10%) Query: 11 ISQQFNAELEDVRSHLLAMGGLVEKQVNDAVNALIDADSGLAQQVREIDDQINQMERNID 70 + QF + +R +KQVN A+ A +D + A+Q+ ++DQI+++ Sbjct: 139 LVNQFKTTDQYLR--------DQDKQVNIAIGASVDQINNYAKQIASLNDQISRLTGVGA 190 Query: 71 EECVR-ILARRQPAASDLRLIISISKSV 97 +L +R S+L I+ + SV Sbjct: 191 GASPNNLLDQRDQLVSELNQIVGVEVSV 218
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 104 bits (260), Expect = 5e-29 Identities = 78/261 (29%), Positives = 119/261 (45%), Gaps = 24/261 (9%) Query: 9 GQVALISGAGSELGIGFAIARRLAREGVRLL-ITASSERIRQRAEELSACGHDVRAASAD 67 G++A I+GA GIG A+AR LA +G + + + E++ + L A A AD Sbjct: 8 GKIAFITGAAQ--GIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 68 LTDEAQVQGLLDWAEAQWGRVDILVNNAGMAQLDSAEPFSAVEATSLRDWQLSLSRNLTS 127 + D A + + E + G +DILVN AG+ + + + S +W+ + S N T Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRP------GLIHSLSDEEWEATFSVNSTG 119 Query: 128 AFLLTRGLLPGMRERGYGRIVNVASTTGTRGSNPGEAAYSAAKAGLVGWSMGLALEVAKS 187 F +R + M +R G IV V S AAY+++KA V ++ L LE+A+ Sbjct: 120 VFNASRSVSKYMMDRRSGSIVTVGSNPAGV-PRTSMAAYASSKAAAVMFTKCLGLELAEY 178 Query: 188 GITVNSVAPG-------WIATASSTAEER-------QAALASPSGRAGRPEEVAAAVAFL 233 I N V+PG W A E+ P + +P ++A AV FL Sbjct: 179 NIRCNIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFL 238 Query: 234 ASPEASFVNGELLVVDGGNCL 254 S +A + L VDGG L Sbjct: 239 VSGQAGHITMHNLCVDGGATL 259
>RTXTOXINA#Gram-negative bacterial RTX toxin determinant A family signature. Length = 1024 Score = 31.9 bits (72), Expect = 0.008 Identities = 11/44 (25%), Positives = 23/44 (52%) Query: 360 PVAVAVSAITTLLTPYLIRAADPLSQHLANAMPQRMARIFGHYG 403 PV+ V A+T +++ L + + +H+A+ M +A +G Sbjct: 394 PVSALVGAVTGIISGILEASKQAMFEHVASKMADVIAEWEKKHG 437
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.8 bits (80), Expect = 6e-04 Identities = 16/48 (33%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 286 AATLFLFMLLQPIVGALSDKIGRRPILIAFGVLGTVFTYPILSTLHSV 333 A + P++GALSD+ GRRP+L+ + G Y I++T + Sbjct: 50 ALYALMQFACAPVLGALSDRFGRRPVLLV-SLAGAAVDYAIMATAPFL 96 Score = 34.4 bits (79), Expect = 9e-04 Identities = 37/192 (19%), Positives = 74/192 (38%), Gaps = 33/192 (17%) Query: 49 KAFFPQGDMTAQLLNTAAIFAVGFLMRPIGGWLMGIYADRKGRKAALLASVLLMCFGSLI 108 + D+TA A++A LM+ ++G +DR GR+ LL S+ I Sbjct: 33 RDLVHSNDVTAHYGILLALYA---LMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAI 89 Query: 109 IALTPSYETIGVAAPILLVVARLLQGLSVGGEYGTSATYLSEMANKEQR----GFFSSFQ 164 +A P +L + R++ G++ G + Y++++ + ++R GF S+ Sbjct: 90 MATAPFLW--------VLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGFMSACF 140 Query: 165 YVTLISGQLIALAVLIVLQQTLTVEQLESWGWRVPFFIGA----LCAVVAMFLRRGMEET 220 +++G ++ + + PFF A L + FL + Sbjct: 141 GFGMVAGPVLG-------------GLMGGFSPHAPFFAAAALNGLNFLTGCFLLPESHKG 187 Query: 221 ESFSKKKEEPKE 232 E ++E Sbjct: 188 ERRPLRREALNP 199
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 115 bits (288), Expect = 2e-32 Identities = 66/193 (34%), Positives = 93/193 (48%), Gaps = 17/193 (8%) Query: 137 AEPTPQPPAAAPEPTPPKIEEPKPEPPKPKPVEKPKPKPKPKPKPVENAIPKAKPKPEPK 196 P A P P P EP+PEP P E P KPKPKP KPKP+P Sbjct: 52 PADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKP--------KPKPKPV 103 Query: 197 PKPEPEPSTEASSQPSPSSAAPPPPAPTVGQSTPGAQTAPSGSQGPAGLPSGSLNDSDIK 256 K + +P + P +P + ++ + + + S + S + Sbjct: 104 KKVQEQP------KRDVKPVESRPASPFENTAPARLTSSTATAATSKPVTSVA---SGPR 154 Query: 257 PLRMDPPVYPRMAQARGIEGRVKVLFTITSDGRIDDIQVLESVPSRMFDREVRQAMAKWR 316 L + P YP AQA IEG+VKV F +T DGR+D++Q+L + P+ MF+REV+ AM +WR Sbjct: 155 ALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWR 214 Query: 317 FEPRVSGGKIVAR 329 +EP G IV Sbjct: 215 YEPGKPGSGIVVN 227