>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 71.2 bits (174), Expect = 2e-17 Identities = 29/159 (18%), Positives = 63/159 (39%), Gaps = 7/159 (4%) Query: 3 QKKSTQKRNQLLNAALDVFSTYGFSGASLDEIAQLAQMHKSNIFYYYENKEALYVEVLTT 62 ++++ + R +L+ AL +FS G S SL EIA+ A + + I++++++K L+ E+ Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 63 VLQKWLAPLQTLEVELEPT------EALAHYLIQKIEVSRTQPKASKLFALEIIQGAPHI 116 + + E L H L + R + +F G + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 117 LEILKGPLKKLFKRKAK-VIQTWQEQGKISADIDPELLI 154 ++ + L + + ++ E + AD+ Sbjct: 126 VQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAA 164
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 66.6 bits (162), Expect = 4e-15 Identities = 43/164 (26%), Positives = 64/164 (39%), Gaps = 23/164 (14%) Query: 29 PEQTALIVVDMQNAYTSIGGYLDLAGFDVSKTKPVVENIQKAVTAAHAAGIQVIYFKNGW 88 P + L++ DMQN + +D S + NI+K GI V+Y Sbjct: 28 PNRAVLLIHDMQNYF------VDAFTAGASPVTELSANIRKLKNQCVQLGIPVVY----- 76 Query: 89 DNQYVEAGGAGSPNFHKSNALKTMRKQPELQGKLLAKGGWDFELIDELQPKSQDIVIEKP 148 GS N L G L G ++ ++I EL P+ D+V+ K Sbjct: 77 ------TAQPGSQNPDDRALLTDF------WGPGLNSGPYEEKIITELAPEDDDLVLTKW 124 Query: 149 RYSGFFNTALDSMLRARGIRNLVFVGIATNVCVESTLRDGFFLE 192 RYS F T L M+R G L+ GI ++ T + F + Sbjct: 125 RYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMED 168
>PF05272#Virulence-associated E family protein Length = 892 Score = 28.5 bits (63), Expect = 0.035 Identities = 12/39 (30%), Positives = 18/39 (46%) Query: 65 IVGRSGCGKSTLLRLIAGLEHTSYGEIKFKSARHFREGI 103 + G G GKSTL+ + GL+ S + + E I Sbjct: 601 LEGTGGIGKSTLINTLVGLDFFSDTHFDIGTGKDSYEQI 639
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 34.1 bits (78), Expect = 5e-04 Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 10/85 (11%) Query: 367 RSAEIACVAVDPAYRKSNRGSQILHFLEEKARQEGILQLFVLTTR----TAHWFLEHGFQ 422 A I +AV YRK G+ +LH E A++ L + T H++ +H F Sbjct: 88 GYALIEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFI 147 Query: 423 TASVD-----DLPSAR-QELYNYQR 441 +VD + P+A ++ Y + Sbjct: 148 IGAVDTMLYSNFPTANEIAIFWYYK 172
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 86.6 bits (214), Expect = 2e-22 Identities = 54/203 (26%), Positives = 89/203 (43%), Gaps = 6/203 (2%) Query: 13 LKGRIILITGAGDGIGRAAAMSYALHGATVVLHGRTLNKLEVIYDEIESLGAPQPAILPL 72 ++G+I ITGA GIG A A + A GA + KLE + A P Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKV-VSSLKAEARHAEAFPA 64 Query: 73 QLSSASDRDYELLFNTLEDQFGRLDGILHNAGILGERVPLAH-YPADVWDDVMAVNLRAP 131 + ++ D +E + G +D +++ AG+L R L H + W+ +VN Sbjct: 65 DVRDSAAIDEIT--ARIEREMGPIDILVNVAGVL--RPGLIHSLSDEEWEATFSVNSTGV 120 Query: 132 FVLTQALLPLLERSDNASVVFASSGVGREARALWGAYSVSKVAIEAVSKIFASEHVYPNI 191 F ++++ + + S+V S R AY+ SK A +K E NI Sbjct: 121 FNASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNI 180 Query: 192 RFNCINPGATRTAMRAKAYPEED 214 R N ++PG+T T M+ + +E+ Sbjct: 181 RCNIVSPGSTETDMQWSLWADEN 203
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 58.1 bits (140), Expect = 1e-12 Identities = 30/116 (25%), Positives = 51/116 (43%), Gaps = 9/116 (7%) Query: 13 MNPDRHQQFLIRKERILSVAERLLLENN-QEITLDELVAELDIAKGTLYKHFKSKNELLL 71 M Q+ ++ IL VA RL + +L E+ + +G +Y HFK K++L Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 72 ELVIQNERRLLEISQKHHHDFKEYAPIYMLHHLLAPARTILLHQLEENLTMTESKL 127 E+ +E + E+ ++ F L+ R IL+H LE +T +L Sbjct: 61 EIWELSESNIGELELEYQAKFPG--------DPLSVLREILIHVLESTVTEERRRL 108
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.9 bits (137), Expect = 3e-12 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 6/142 (4%) Query: 6 ERKQQSRQALLDAALQLSTGGRSFSSISLREVAREVGLVPTAFYRHFQDMDALGQELVDQ 65 + Q++RQ +LD AL+L + SS SL E+A+ G+ A Y HF+D L E+ + Sbjct: 7 QEAQETRQHILDVALRL-FSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 66 VALHIKSLIHQLGQSYLQQVSTHPDSSIELFFQAINHSP-----LEWQFMIAERWGGSAA 120 +I L + + + + ++ +E F E G A Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAV 125 Query: 121 VRQAIAREIEDLIEDLATDLRK 142 V+QA + + + L+ Sbjct: 126 VQQAQRNLCLESYDRIEQTLKH 147
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 183 bits (465), Expect = 4e-60 Identities = 94/227 (41%), Positives = 135/227 (59%) Query: 2 MKKIGLALIASSMTVTAFAASIGASSPQKDQLGYSYGYVMGRTNADTLKDLNVDAFVQGL 61 MK + A++ +M+ A + + KD+L YS G +G+ + D+N D +G+ Sbjct: 3 MKLVTAAIMGLAMSTAMAATDATSLTTDKDKLSYSIGADLGKNFKNQGIDINPDVLAKGM 62 Query: 62 KEGAQGKDSALSDEAMAKVLSQYKKQVEAKQLYAFQQLAQDNLKRGEAFLAENAKKSGVI 121 ++G G L++E M VLS+++K + AK+ F + A++N +G+AFL+ N K G++ Sbjct: 63 QDGMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPGIV 122 Query: 122 STKSGLQYQVLSAGKGKSPKASSRVKVNYEGRLLDGTVFDSSIARNHPVEFQLSQVIPGW 181 SGLQY+++ AG G P S V V Y G L+DGTVFDS+ P FQ+SQVIPGW Sbjct: 123 VLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIPGW 182 Query: 182 TEGLQLMKEGEKARLFIPAKLAYGEVGSGDAIGPNSTLIFDIELLEI 228 TE LQLM G +F+PA LAYG G IGPN TLIF I L+ + Sbjct: 183 TEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISV 229
>INFPOTNTIATR#Macrophage infectivity potentiator signature. Length = 233 Score = 151 bits (383), Expect = 9e-48 Identities = 87/230 (37%), Positives = 131/230 (56%), Gaps = 11/230 (4%) Query: 13 LGGAALIPVYYASQHPATDVGSKADKNATPVQKISYALGYEVA-NQTPAELDVN--TFVQ 69 L AA++ + ++ ATD S T K+SY++G ++ N +D+N + Sbjct: 5 LVTAAIMGLAMSTAMAATDATSLT----TDKDKLSYSIGADLGKNFKNQGIDINPDVLAK 60 Query: 70 GIRDGHAHAPAAYTEEQLQAAYKEYQQEMQKKQLDQTHQSA----SSSNNFLAENAKKEG 125 G++DG + A TEEQ++ ++Q+++ K+ + ++ A + + FL+ N K G Sbjct: 61 GMQDGMSGAQLILTEEQMKDVLSKFQKDLMAKRSAEFNKKAEENKAKGDAFLSANKSKPG 120 Query: 126 VKTTASGLQYKIITEGTGKRPSASSVVKVNYKGQLTDGKVFDSSYERGQPVEFPLNQVIP 185 + SGLQYKII GTG +P S V V Y G L DG VFDS+ + G+P F ++QVIP Sbjct: 121 IVVLPSGLQYKIIDAGTGAKPGKSDTVTVEYTGTLIDGTVFDSTEKAGKPATFQVSQVIP 180 Query: 186 GWTEGLQLLKEGGKATLYIPAKLGYGEQGVPGMIPPNSTLIFDVELLEVK 235 GWTE LQL+ G +++PA L YG + V G I PN TLIF + L+ VK Sbjct: 181 GWTEALQLMPAGSTWEVFVPADLAYGPRSVGGPIGPNETLIFKIHLISVK 230
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 186 bits (473), Expect = 2e-58 Identities = 87/360 (24%), Positives = 150/360 (41%), Gaps = 56/360 (15%) Query: 2 MKILITGGAGFIGSAVVRHIIQNTDNTVLNVDKLT--YAGNL-ESLAKVADNSRYQFSQT 58 MK L+TG AGFIG V + +++ V+ +D L Y +L ++ ++ +QF + Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGH-QVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKI 59 Query: 59 DICDRAALDQLFETFQPDAVMHLAAESHVDRSITGPAAFIETNILGTYQLLEAARHYWNG 118 D+ DR + LF + + V V S+ P A+ ++N+ G +LE RH Sbjct: 60 DLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRH---- 115 Query: 119 LAQDKKAEFRFHHI---STDEVYGDLEG---TEDLFVETTPYAPSSPYSASKASSDHLVR 172 + H+ S+ VYG + D V+ P S Y+A+K +++ + Sbjct: 116 --------NKIQHLLYASSSSVYGLNRKMPFSTDDSVDH----PVSLYAATKKANELMAH 163 Query: 173 AWHRTYGLPVVLTNCSNNYGPYHFPEKLIPLVILNALAGKPLPVYGNGAQIRDWLYVEDH 232 + YGLP YGP+ P+ + L GK + VY G RD+ Y++D Sbjct: 164 TYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDI 223 Query: 233 ARALYKVV------------------TEAKVGETYNIGGHNEQQNIDVVKAICNLLEELA 274 A A+ ++ YNIG + + +D ++A+ + L Sbjct: 224 AEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDAL---- 279 Query: 275 PNKPEGIANYQDLITYVKDRPGHDLRYAIDASKIKKDLGWVPQETFESGLRKTVEWYLAN 334 E N L +PG L + D + + +G+ P+ T + G++ V WY Sbjct: 280 --GIEAKKNMLPL------QPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 58.6 bits (142), Expect = 5e-12 Identities = 47/202 (23%), Positives = 78/202 (38%), Gaps = 32/202 (15%) Query: 1 MKILILGKNGQVGWELQRSLQPLG-EVIALD---RYEDV-----------EHGFS---GD 42 MK L+ G G +G+ + + L G +V+ +D Y DV + GF D Sbjct: 1 MKYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKID 60 Query: 43 ITNFEAIEKVIQTFQPDIVLNATAYTAVDKA-ESEVEQADLVNHIAVKHLAEQCKAID-A 100 + + E + + + + V + AV + E+ AD N ++ E C+ Sbjct: 61 LADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYAD-SNLTGFLNILEGCRHNKIQ 119 Query: 101 LLIHYSTDYVFNGQGTAAWQEDD-TTEPQNAYGKTKRNGE-IALEQSQ---VKFINLRTS 155 L++ S+ V+ + DD P + Y TK+ E +A S + LR Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179 Query: 156 WVYASRG------HNFIKTMLK 171 VY G F K ML+ Sbjct: 180 TVYGPWGRPDMALFKFTKAMLE 201
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 243 bits (623), Expect = 5e-81 Identities = 95/336 (28%), Positives = 153/336 (45%), Gaps = 29/336 (8%) Query: 19 LITGVAGFIGSNLLETLLKLDQRVIGLDNFATGHQHNLDEVQGLVSREQWNNFKFIRGDI 78 L+TG AGFIG ++ + LL+ +V+G+DN + +L + + F+F + D+ Sbjct: 4 LVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQ--ARLELLAQPGFQFHKIDL 61 Query: 79 CQLQDCQA--ACEGVDYVLHQAALGSVPRSLVDPITTNSVNIGGFLNMLVAARDAQVKSF 136 + A + V +V SL +P N+ GFLN+L R +++ Sbjct: 62 ADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL 121 Query: 137 TYAASSSTYGDHPALPKLEDHI-GKPLSPYAVTKYVNELYADVFARSYGFYCIGLRYFNV 195 YA+SSS YG + +P D P+S YA TK NEL A ++ YG GLR+F V Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181 Query: 196 FGQRQDPNGAYAAVIPKWTAAMIQGEDVFINGDGETSRDFCFIENTVQANL--------- 246 +G P+ A K+T AM++G+ + + G+ RDF +I++ +A + Sbjct: 182 YGPWGRPDMAL----FKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHA 237 Query: 247 ------LAATTQDAAAKNQVYNVAVGDRTTLNQLFATLQSALAENGIHYNKPAVYREFRA 300 T + A +VYN+ L L+ AL GI K + Sbjct: 238 DTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDAL---GIEAKK--NMLPLQP 292 Query: 301 GDVRHSQADIGKISQLLGYQPEYRFAQGVHKAMHWY 336 GDV + AD + +++G+ PE GV ++WY Sbjct: 293 GDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 371 bits (955), Expect = e-130 Identities = 188/362 (51%), Positives = 239/362 (66%), Gaps = 10/362 (2%) Query: 1 MPRPIQAVIHLEALAHNLKIVRASAPESQVFAVVKANAYGHGIERVYQAFKQADGFALLD 60 M RPIQA + L+AL NL IVR +A ++V++VVKANAYGHGIER++ A DGFALL+ Sbjct: 1 MTRPIQASLDLQALKQNLSIVRQAATHARVWSVVKANAYGHGIERIWSAIGATDGFALLN 60 Query: 61 IEEAKRLRALGWTGPILLLEGIFSPQDLFDCVQYQLSFTVHHDVQIDWIEGHPEDAQFDI 120 +EEA LR GW GPIL+LEG F QDL Q++L+ VH + Q+ ++ A DI Sbjct: 61 LEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKAPLDI 120 Query: 121 FLKMNSGMNRLGFKPVQYRHAWQRLNALSQVRHLTHMMHFSDADGERFGESGITYQHDLF 180 +LK+NSGMNRLGF+P + WQ+L A++ V +T M HF++A+ GI+ Sbjct: 121 YLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAE----HPDGISGAMARI 176 Query: 181 EDTIRDLPGPKSVSNSAAILRHP-LHSDVVRGGIMLYGSSPDYPTHGLHDWSLKPTMSLR 239 E L +S+SNSAA L HP H D VR GI+LYG+SP + + L+P M+L Sbjct: 177 EQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIANTGLRPVMTLS 236 Query: 240 SEIIAIQMLEPNESVGYGSSFVADQPLRIGIVACGYADGYQRISPTGTPVLVDGIETRTI 299 SEII +Q L+ E VGYG + A RIGIVA GYADGY R +PTGTPVLVDG+ T T+ Sbjct: 237 SEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTGTPVLVDGVRTMTV 296 Query: 300 GRVSMDMLAVDLSAVPKARIGSEVVLWGYSSTGVILPIDDVAAASGTVGYELMCAVTARV 359 G VSMDMLAVDL+ P+A IG+ V LWG + IDDVAAA+GTVGYELMCA+ RV Sbjct: 297 GTVSMDMLAVDLTPCPQAGIGTPVELWGKE-----IKIDDVAAAAGTVGYELMCALALRV 351 Query: 360 PF 361 P Sbjct: 352 PV 353
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 680 bits (1755), Expect = 0.0 Identities = 242/861 (28%), Positives = 401/861 (46%), Gaps = 52/861 (6%) Query: 35 TESTSASEAYTFDPHLFKGTGLNQELIERFNHSSQLQAGQYTLDVYVNKRFIDRQQIKLV 94 ++ +S F+P + RF + +L G Y +D+Y+N ++ + + Sbjct: 38 AQAPLSSAELYFNPRFLADDPQAVADLSRFENGQELPPGTYRVDIYLNNGYMATRDVTFN 97 Query: 95 DGSEQANTIDACWTTSLLERAGILGSPDFQKTRAEATHQILADECLKLDQIAPGSQSDFD 154 + I C T + L G+ + + + D C+ L + + + D Sbjct: 98 T-GDSEQGIVPCLTRAQLASMGLNTAS------VSGMNLLADDACVPLTSMIHDATAQLD 150 Query: 155 FSNLRLDLSIPQQFLKNLPRGYVSSEELDAGESIGFVNYSGNYYRTESKFEHKQRHESGF 214 RL+L+IPQ F+ N RGY+ E D G + G +NY+ + +++ + Sbjct: 151 VGQQRLNLTIPQAFMSNRARGYIPPELWDPGINAGLLNYNFSGNSVQNR--IGGNSHYAY 208 Query: 215 VSLNAGVNAGKWQYRQQSNFSI-----DNDSHRHWNHIRSYLQRPIDSWASVLTLGQQYG 269 ++L +G+N G W+ R + +S + S W HI ++L+R I S LTLG Y Sbjct: 209 LNLQSGLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLERDIIPLRSRLTLGDGYT 268 Query: 270 SGQFFSTLPYLGLSIQTDERMRPDSMRGYAPVIRGTAQTNAKVSIEQNGREIYQISVAPG 329 G F + + G + +D+ M PDS RG+APVI G A+ A+V+I+QNG +IY +V PG Sbjct: 269 QGDIFDGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQVTIKQNGYDIYNSTVPPG 328 Query: 330 PFEIKDLYPTNFEGNLKVVVTEADGTVHTHDVPYAAVPNSLRAGLYNYNFSLG--RTDLD 387 PF I D+Y G+L+V + EADG+ VPY++VP R G Y+ + G R+ Sbjct: 329 PFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQREGHTRYSITAGEYRSGNA 388 Query: 388 RAQDAYFSDFNYEYGLSNSITLNGGVRLSQNYQAALFGGVWGS-SLGALGTNVTYSRAEL 446 + + F +GL T+ GG +L+ Y+A FG +LGAL ++T + + L Sbjct: 389 QQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFGIGKNMGALGALSVDMTQANSTL 448 Query: 447 ANLSGKDTTDGWMANITYSKTIQSTNTTIAIAGYRYSTEGYRELNDVL------------ 494 + S DG Y+K++ + T I + GYRYST GY D Sbjct: 449 PDDS---QHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSGYFNFADTTYSRMNGYNIETQ 505 Query: 495 -GLAYAAKQGGDWSSNTYLQRSRFQINLSQQFGRFGSFYVAGSTQSYRDERKRDTAFQAG 553 G+ + D+ + Y +R + Q+ ++QQ GR + Y++GS Q+Y D FQAG Sbjct: 506 DGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYLSGSHQTYWGTSNVDEQFQAG 565 Query: 554 FSKSIGIMSFNLNYTRQKVYSMRDDSLKHEYSDNFGGISVHIPLGKARNPLRPTL----S 609 + + +++ L+Y+ K ++ + D ++V+IP + S Sbjct: 566 LNTAFEDINWTLSYSLTK------NAWQKG-RDQMLALNVNIPFSHWLRSDSKSQWRHAS 618 Query: 610 AYYNQS---KNNENYQLALNGALDPNYSLNYTLGV---NGSSDQTDTTYTAGLYKRFASL 663 A Y+ S + G L + +L+Y++ G + +T A L R Sbjct: 619 ASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGSTGYATLNYRGGYG 678 Query: 664 QLGANTSYGNQYWQNSMSANGAVALHSGGVTFGPYLTETFGLIEAKGAKGAKVISSPYSK 723 S+ + Q +G V H+ GVT G L +T L++A GAK AKV + + Sbjct: 679 NANIGYSHSDDIKQLYYGVSGGVLAHANGVTLGQPLNDTVVLVKAPGAKDAKVENQTGVR 738 Query: 724 IDRFGYALVPSLSPYRYNSVILDPQGIANNIELEGGEQRVAPYAGASVKIKFVTRTGYSV 783 D GYA++P + YR N V LD +A+N++L+ V P GA V+ +F R G + Sbjct: 739 TDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPTRGAIVRAEFKARVGIKL 798 Query: 784 LIQSRLNNQHMIPMGTDVLNANEEVIGMVGQGGQMYLRVAQPKGILHLRWTDQQGASSCS 843 L+ NN+ +P G V + + + G+V GQ+YL G + ++W +++ A C Sbjct: 799 LMTLTHNNKP-LPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQVKWGEEENA-HCV 856 Query: 844 LPYAISDIELNQPLIKLSAVC 864 Y + Q L +LSA C Sbjct: 857 ANYQLPPESQQQLLTQLSAEC 877
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 47.1 bits (112), Expect = 8e-08 Identities = 62/372 (16%), Positives = 125/372 (33%), Gaps = 44/372 (11%) Query: 33 TMGYIFSAFGWAYVIGQVPGGWLLDKFGARKVYFWSILLWSIFTVLLGFVDIFGSIPLII 92 G + + + G L D+FG R V S+ ++ ++ Sbjct: 44 HYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFL------- 96 Query: 93 ASLFILRFLVGLSESPAFPGNSQIVAAWFPTKERGTAAASFNSAQYFATVIFAPFMGWLV 152 L+I R + G++ + +A ER F SA + ++ P +G L+ Sbjct: 97 WVLYIGRIVAGITGAT-GAVAGAYIADITDGDER-ARHFGFMSACFGFGMVAGPVLGGLM 154 Query: 153 THIHWQSVFWIMGAIGIVIAFIWLKVIYSPEKHPRINKEELTYLQGNGAITSMGENKSKT 212 + F+ A+ + F+ PE H + + + Sbjct: 155 GGFSPHAPFFAAAALNG-LNFL-TGCFLLPESHKGERRPL----------------RREA 196 Query: 213 LDQKNKMSWSNVKKLLSSRMLLGIFIAQYCITCLTYFFLTWFPVYLVKERHMTILQAGFA 272 L+ W+ ++++ M + FI Q + + ++ H G + Sbjct: 197 LNPLASFRWARGMTVVAALMAVF-FIMQ----LVGQVPAALWVIFGEDRFHWDATTIGIS 251 Query: 273 AVLPALCGFIGGILGGIISDRLIRMNKSLSFSRKFPIVLGMLLSTS--IIVCNYVDSQTA 330 A G + + +I+ + + ++LGM+ + I++ A Sbjct: 252 L---AAFGILHSLAQAMITGPVAAR-----LGERRALMLGMIADGTGYILLAFATRGWMA 303 Query: 331 IVFFMSLAFFGKGFGALGWAVMSDVAPKEMIGLSGGLFNTFGNTAGIIIPIAIGYIVAST 390 + LA G G AL A++S +E G G + I+ P+ I A++ Sbjct: 304 FPIMVLLASGGIGMPALQ-AMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAAS 362 Query: 391 -GSFNGALVFVG 401 ++NG G Sbjct: 363 ITTWNGWAWIAG 374 Score = 29.8 bits (67), Expect = 0.024 Identities = 28/155 (18%), Positives = 54/155 (34%), Gaps = 9/155 (5%) Query: 25 QELGLTSVTMGYIFSAFGWAYVIGQ-VPGGWLLDKFGARKVYFWSILLWSIFTVLLGFVD 83 + T+G +AFG + + Q + G + + G R+ ++ +LL F Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALMLGMIADGTGYILLAFA- 297 Query: 84 IFGSIPLIIASLFILRFLVGLSESPAFPGN-SQIVAAWFPTKERGTAAASFNSAQYFATV 142 + + +L G PA S+ V + +G+ AA + + Sbjct: 298 --TRGWMAFPIMVLLAS--GGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPL 353 Query: 143 IFAPFMGWLVTHIHWQSVFWIMGAIGIVIAFIWLK 177 +F + W WI GA ++ L+ Sbjct: 354 LFTAIYA--ASITTWNGWAWIAGAALYLLCLPALR 386
>FLGBIOSNFLIP#Escherichia coli: Flagellar biosynthetic protein FliP signature. Length = 245 Score = 28.6 bits (64), Expect = 0.046 Identities = 10/54 (18%), Positives = 21/54 (38%), Gaps = 3/54 (5%) Query: 19 APTIESINATDYQPTGYLFSQATLDEVDQAAQAAYQAFLKYQHTTQQQRADFLD 72 +P I+ I YQP + + ++ E + + F+ + T + F Sbjct: 102 SPVIDKIYVDAYQP--FSEEKISMQEALEKGAQPLREFM-LRQTREADLGLFAR 152
>adhesinmafb#Neisseria meningitidis: adhesin MafB signature. Length = 467 Score = 32.3 bits (73), Expect = 0.013 Identities = 24/112 (21%), Positives = 45/112 (40%), Gaps = 7/112 (6%) Query: 301 SAWTTDLTGADQATASSSQQIEKLNQNLTAYQERQAKYFIAQTTVRDAQVGYWFELQGHP 360 +A + D + + + S +L QN + R+A + +R G + G Sbjct: 334 AAVSGDFADSYKKKLALSDSARQLYQNA---KYREALDIHYEDLIRRKTDGSSKFINGR- 389 Query: 361 EIDQHDLADRQFLIYEKRFFNQNNLPKDIQQQFEYLLMHSALKTSNQQERQG 412 EID LI KR + + PK+ Q + + ++ +NQQ ++ Sbjct: 390 EIDAVT---NDALIQAKRTISAIDKPKNFLNQKNRKQIKATIEAANQQGKRA 438
>PF05272#Virulence-associated E family protein Length = 892 Score = 30.8 bits (69), Expect = 0.005 Identities = 12/21 (57%), Positives = 13/21 (61%) Query: 38 IVTLIGPNGAGKSTLIKILLG 58 V L G G GKSTLI L+G Sbjct: 598 SVVLEGTGGIGKSTLINTLVG 618
>ADHESNFAMILY#Adhesin family signature. Length = 309 Score = 90.3 bits (224), Expect = 4e-23 Identities = 45/229 (19%), Positives = 81/229 (35%), Gaps = 17/229 (7%) Query: 26 PLVVSTHPLYLIAKEVTQGVEEPQLLLG-NQSGHDIQLTPAHRKAIQDASLVVWLGKTHE 84 +V + + I K + + ++ Q H+ + P K +A L+ + G E Sbjct: 34 KVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTSEADLIFYNGINLE 93 Query: 85 ----APLAKLLDNNPKAISIINSQIV---TGLPQRTTRGVPIPNTVDTHVWLDPNNAIRI 137 A KL++N A N G+ G D H WL+ N I Sbjct: 94 TGGNAWFTKLVEN---AKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIF 150 Query: 138 GFFIAALRSQQMPENQTKYWNNARKFAREMLQAAQPYNTTASPKP-----YWSYHDAYQY 192 IA S + P N+ Y N +++ ++ + + + P + A++Y Sbjct: 151 AKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKY 210 Query: 193 LERALNLKFAGAMTDDPHVAPTVAQIKYLNDN-RPSERMCLMAEAHASK 240 +A + A + T QIK L + R ++ L E+ Sbjct: 211 FSKAYGVPSAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDD 259
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 67.0 bits (163), Expect = 1e-15 Identities = 19/70 (27%), Positives = 40/70 (57%) Query: 9 TKDRILQISLQLFNERGERSVTTNHIAAELGISPGNLYYHFRNKQEIIKELMEHYQKETL 68 T+ IL ++L+LF+++G S + IA G++ G +Y+HF++K ++ E+ E + Sbjct: 12 TRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESNIG 71 Query: 69 EMLALPEDRL 78 E+ + + Sbjct: 72 ELELEYQAKF 81
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 48.0 bits (114), Expect = 9e-09 Identities = 36/196 (18%), Positives = 73/196 (37%), Gaps = 7/196 (3%) Query: 63 VKIQAPPPLPPKPKEEPKKEQPKPKKEVKEVKVVEKVAPPPKKVEKVQQVKKAETPKQVV 122 V + AP L P +P +P + E + + E P +EK + K + Sbjct: 52 VTMVAPADLEPPQAVQPPP-EPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKK 110 Query: 123 KVEPQVDVKPLTTNTTITEKVAEKPKPQPAAQPQVNREPSPKNVSIGGSGVQWSRTPRPS 182 +P+ DVKP+ + + +P + + K V+ SG + +P Sbjct: 111 VEQPKRDVKPVESRPASPFENTAPARPTSSTA----TAATSKPVTSVASGPRALSRNQPQ 166 Query: 183 YTNRDLQ-GETRSIVVMIEADETGKIINARITRSSGIPALDEKILRSVRGARFKPYK-EN 240 Y R + V + G++ N +I + + ++ ++R R++P K + Sbjct: 167 YPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGKPGS 226 Query: 241 GVAYPIRAEQPFDLTL 256 G+ I + + Sbjct: 227 GIVVNILFKINGTTEI 242
>BORPETOXINA#Bordetella pertussis toxin A subunit signature. Length = 269 Score = 33.2 bits (75), Expect = 2e-04 Identities = 21/69 (30%), Positives = 29/69 (42%), Gaps = 4/69 (5%) Query: 26 LVLMIIFLVTATVANPSVPLSLPKTTAEIQPPPPKEITISINSNGDVSWGQEAITLDELQ 85 L + I VTA V +P+ P T PP+++ NG +WG LD L Sbjct: 16 LTWLAILAVTAPVTSPAWADDPPATVYRYDSRPPEDVF----QNGFTAWGNNDNVLDHLT 71 Query: 86 KRFQEAGQS 94 R + G S Sbjct: 72 GRSCQVGSS 80
>ACETATEKNASE#Acetate kinase family signature. Length = 400 Score = 426 bits (1096), Expect = e-150 Identities = 176/402 (43%), Positives = 253/402 (62%), Gaps = 18/402 (4%) Query: 5 VLVINCGSSSIKYALV-SERREDRIYGLAENLGSADARIKGITVGGAPLELSIPYADHEK 63 +LVINCGSSS+KY L+ S+ GLAE +G D+ + G +++ DH+ Sbjct: 3 ILVINCGSSSLKYQLIESKDGNVLAKGLAERIGINDSLLT-HNANGEKIKIKKDMKDHKD 61 Query: 64 ALETLLGRLANYKPQ---------AIGHRVVHGGTS-TKAELLTPEIIEKIREATPLAPL 113 A++ +L L N A+GHRVVHGG T + L+T ++++ I + LAPL Sbjct: 62 AIKLVLDALVNSDYGVIKDMSEIDAVGHRVVHGGEYFTSSVLITDDVLKAITDCIELAPL 121 Query: 114 HNPAHLVGIDATMRLFPELPQVAVFDTAFHQTMPAHAYRYALPKFLYTEHNVRRYGFHGT 173 HNPA++ GI A ++ P++P VAVFDTAFHQTMP +AY Y +P YT++ +R+YGFHGT Sbjct: 122 HNPANIEGIKACTQIMPDVPMVAVFDTAFHQTMPDYAYLYPIPYEYYTKYKIRKYGFHGT 181 Query: 174 SHAYVSERGSELAG-SFKQGGWLTAHLGNGSSTCAIWNGESVDTSMGLTPLEGIVMGTRS 232 SH YVS+R +E+ + +T HLGNGSS A+ NG+S+DTSMG TPLEG+ MGTRS Sbjct: 182 SHKYVSQRAAEILNKPIESLKIITCHLGNGSSIAAVKNGKSIDTSMGFTPLEGLAMGTRS 241 Query: 233 GDVDPSIHSFLASNLGWDIFKIDKMLNKESGLLGLSDNLSNDMRTLIEAS-EQGNEDATL 291 G +DPSI S+L ++ +LNK+SG+ G+S +S+D R L +A+ + G++ A L Sbjct: 242 GSIDPSIISYLMEKENISAEEVVNILNKKSGVYGIS-GISSDFRDLEDAAFKNGDKRAQL 300 Query: 292 AIEVFCYRLAKSLAALSCALPRLDGLFFTGGIGENSAYIREKTMAYLPHFGFKLNIEQNN 351 A+ VF YR+ K++ + + A+ +D + FT GIGEN IRE + L GFKL+ E+N Sbjct: 301 ALNVFAYRVKKTIGSYAAAMGGVDVIVFTAGIGENGPEIREFILDGLEFLGFKLDKEKNK 360 Query: 352 TLKRGTEGRID-QGTGPQIWVIPTDEEGRIAKETEQVVEHAK 392 RG E I + + V+PT+EE IAK+TE++VE K Sbjct: 361 V--RGEEAIISTADSKVNVMVVPTNEEYMIAKDTEKIVESLK 400
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 31.1 bits (70), Expect = 0.004 Identities = 18/99 (18%), Positives = 32/99 (32%), Gaps = 4/99 (4%) Query: 132 HFGNIE-LLRAIKAEHPQKINVLVYQKHATQFNAFLKKLNDQVDV---NLISVDELGLET 187 HF + L I I L + A L L + + + ++ + L Sbjct: 51 HFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLM 110 Query: 188 AILLEEKMQQGEWVIVAADRAPVHSDRVQHIEFLGKEAI 226 I+ + GE +V + + + IE K I Sbjct: 111 EIIFHKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCI 149
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 50.6 bits (121), Expect = 2e-08 Identities = 34/150 (22%), Positives = 57/150 (38%), Gaps = 19/150 (12%) Query: 621 QSLFMYALLALAVGLGLIYGWRSVFPLVLPVSLALLTTFAIQAWLGVEINLFSIMGTFLI 680 ++LF +L V + R+ + V + LL TFAI A G IN ++ G L Sbjct: 342 KTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLA 401 Query: 681 VGIGVDYAI-----FYRH---GHDHPQ--------VVGMALF---LCMMSTLLGFGLLSL 721 +G+ VD AI R P+ + AL + + + + Sbjct: 402 IGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGG 461 Query: 722 SHTYAIHCFGLTVLFGVIFSFIYATLFTRA 751 S F +T++ + S + A + T A Sbjct: 462 STGAIYRQFSITIVSAMALSVLVALILTPA 491 Score = 44.8 bits (106), Expect = 1e-06 Identities = 39/228 (17%), Positives = 84/228 (36%), Gaps = 31/228 (13%) Query: 235 SNYGTQSAQKEISTIGLGSTLGLILLVWFGFRSFRPLLTEFIAVSTGSLVAFAVTHWVFG 294 + + S + + T+ L + L+++ ++ R L IAV L FA+ Sbjct: 330 TPFVQLSIHEVVKTLFEAIML-VFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGY 388 Query: 295 EIHLMTLVFGASLIGVCVDFSF--------YFMAMQSQHRNITGFEVLKPLLPSLFMGLM 346 I+ +T+ IG+ VD + M + + T + + + +L M Sbjct: 389 SINTLTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEAT-EKSMSQIQGALVGIAM 447 Query: 347 TTVVAYV---FLSFTPFPGFKQIAVFSIVGLVSAWITSILLLPRLPALNAEPAIRR-LKW 402 ++ F + ++Q ++ + + + + +++L P L A +P + Sbjct: 448 VLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHEN 507 Query: 403 IGTFRVWFQS-----------------KRLLGYVSVICILVAGLSSLF 433 G F WF + Y+ + ++VAG+ LF Sbjct: 508 KGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLF 555 Score = 35.6 bits (82), Expect = 8e-04 Identities = 26/151 (17%), Positives = 61/151 (40%), Gaps = 20/151 (13%) Query: 619 QAQSLFMYALLALAVGLGLIY-GWRSVFPLVLPVSLALLTTFAIQAWLGVEINLFSIMGT 677 QA +L + + + + L +Y W ++L V L ++ + +++ ++G Sbjct: 871 QAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGL 930 Query: 678 FLIVGIGVDYAIFY---------RHGHDHPQVVGMA-------LFLCMMSTLLGFGLLSL 721 +G+ AI + G + MA + + ++ +LG L++ Sbjct: 931 LTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAI 990 Query: 722 SHTY---AIHCFGLTVLFGVIFSFIYATLFT 749 S+ A + G+ V+ G++ + + A F Sbjct: 991 SNGAGSGAQNAVGIGVMGGMVSATLLAIFFV 1021
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 105 bits (264), Expect = 8e-30 Identities = 68/250 (27%), Positives = 115/250 (46%), Gaps = 15/250 (6%) Query: 3 RRILVTGSSRGIGKAIALQLAQAGFDITVHARSRLDEAQAVAEQIKQLGRNSHVLMFDVN 62 + +TG+++GIG+A+A LA G I ++ + V +K R++ DV Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAA-VDYNPEKLEKVVSSLKAEARHAEAFPADVR 67 Query: 63 ARDTVREMLEQDIEVHGAFYGVVLNAGLTHDAAFPALSDHEWDDVISTSLDGFYNVLKPL 122 + E+ + G +V AG+ +LSD EW+ S + G +N + Sbjct: 68 DSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRS- 126 Query: 123 IMPMIHLKQGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALSLELAKRKITVNCVA 182 + + ++ G IVT+ S + Y+++KA + TK L LELA+ I N V+ Sbjct: 127 VSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVS 186 Query: 183 PGLIETEM-----VTEEVKQHALK--------MIPLQRMGHVDEVASVVKFLCSDEASYI 229 PG ET+M E + +K IPL+++ ++A V FL S +A +I Sbjct: 187 PGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHI 246 Query: 230 TRQVISVNGG 239 T + V+GG Sbjct: 247 TMHNLCVDGG 256
>PF06580#Sensor histidine kinase Length = 349 Score = 27.1 bits (60), Expect = 0.009 Identities = 17/78 (21%), Positives = 28/78 (35%), Gaps = 5/78 (6%) Query: 12 FLYYFFATMMIISLLAACYARLFQNGETLDLSA-FYTFFVMMLFARFYYAI----QYGLE 66 + +F A I LLA + L LS F V +++ Y+ Y Sbjct: 88 GMVWFVANTSIWRLLAFINTKPVAFTLPLALSIIFNVVVVTFMWSLLYFGWHFFKNYKQA 147 Query: 67 KIEQINRRERQRQLDLEA 84 +I+Q ++ L A Sbjct: 148 EIDQWKMASMAQEAQLMA 165
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 284 bits (728), Expect = 4e-97 Identities = 91/304 (29%), Positives = 168/304 (55%), Gaps = 14/304 (4%) Query: 18 NERVIPFMKIAKPAAIFSVLLTLASIFFIVTKGLNLGLDFTGGVSAELNYSQPVNQSAVS 77 + F + ++++ +AS+ + GLN G+DF GG + + ++ Sbjct: 10 EKTNFDFFRWQWATFGAAIVMMIASVILPLVIGLNFGIDFKGGTTIRTESTTAIDVGVYR 69 Query: 78 QALDKAGFKDAVVQTLGS------NKDLIVRMPVQDD--------LKVDDLSNALTKAVQ 123 AL+ D ++ + ++R+ +Q+D + +L N + A+ Sbjct: 70 AALEPLELGDVIISEVRDPSFREDQHVAMIRIQMQEDGQGAEGQGAQGQELVNKVETALT 129 Query: 124 LPNNTAVVHKVDAVGGQVGNELYIRSAGAVALALILMLVYVTIRFEFKLAMGAVMSLFHD 183 + + ++VG +V EL + ++ A ++++ Y+ +RFE++ A+GAV++L HD Sbjct: 130 AVDPALKITSFESVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHD 189 Query: 184 IIIIIGAFALFQWQFDLTVLAAVLAVIGFSLNDNIVVSDRIRENFRKIRGATPREIVDIA 243 +++ +G FA+ Q +FDLT +AA+L + G+S+ND +VV DR+REN K + R++++++ Sbjct: 190 VLLTVGLFAVLQLKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVMNLS 249 Query: 244 LTETLRRTIHTSMTLLLVVLAMMFLGGDGLKWFSVAMFVGVFVGTYSSIYIGTAFALWRG 303 + ETL RT+ T MT LL ++ M+ GGD ++ F AM GVF GTYSS+Y+ L+ G Sbjct: 250 VNETLSRTVMTGMTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIVLFIG 309 Query: 304 LNRQ 307 L+R Sbjct: 310 LDRN 313
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 87.2 bits (216), Expect = 6e-22 Identities = 33/137 (24%), Positives = 59/137 (43%), Gaps = 1/137 (0%) Query: 8 PKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDLVVLDVMLPGADGL 67 IL+ +DD + + + L R G +V + ++ R I + DLVV DV++P + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 68 TVCREVRPHY-HQPILMLTARTEDMDQVLGLEMGADDYVAKPVQPRVLLARIRALLRRTD 126 + ++ P+L+++A+ M + E GA DY+ KP L+ I L Sbjct: 64 DLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPK 123 Query: 127 KTVEDEVAQRIEFDDLV 143 + + LV Sbjct: 124 RRPSKLEDDSQDGMPLV 140
>PF06580#Sensor histidine kinase Length = 349 Score = 34.8 bits (80), Expect = 7e-04 Identities = 22/108 (20%), Positives = 41/108 (37%), Gaps = 22/108 (20%) Query: 431 VVQNLVGNAVRY----CNDKVRIS-GGIHPDGHAFICVEDDGAGIAEEDRARVFEAFARL 485 +VQ LV N +++ +I G +G + VE+ G+ + Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKN------------ 306 Query: 486 DDSRTRASGGYGLGLSIVSRIAYWFGGTIQVDESPELGGARFVMQWPA 533 T+ S G GL ++ R+ +G Q+ S + G ++ P Sbjct: 307 ----TKESTGTGL-QNVRERLQMLYGTEAQIKLSEKQGKVNAMVLIPG 349
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 30.1 bits (68), Expect = 0.035 Identities = 32/130 (24%), Positives = 54/130 (41%), Gaps = 39/130 (30%) Query: 619 RFYQVYDPSYYKPEYAIKESWRWLHAIETSLKGKSI----------DWTLLDDVIESVVK 668 RF+ VY P + +P+ A+ +++ A+ L+GKSI D+T +DD+ E++++ Sbjct: 177 RFFTVYGP-WGRPDMAL---FKFTKAM---LEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229 Query: 669 NVPVL---------EAIQDVAPDAGYRVHGL---------KIAREPRRYSGRTALRAPLS 710 V+ E A A YRV+ + + G A + Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKK---- 285 Query: 711 VHEPKQPVDV 720 P QP DV Sbjct: 286 NMLPLQPGDV 295
>ALARACEMASE#Alanine racemase signature. Length = 356 Score = 39.0 bits (91), Expect = 9e-06 Identities = 20/104 (19%), Positives = 37/104 (35%), Gaps = 6/104 (5%) Query: 127 LCIQVNIDHQDSKDGCQPEDVAQLVEEISQLPQVRLRGIMV-IPAPDQITAFTDAKQLFE 185 L I + ++ ++ G QP+ V + +++ + V +M + + A E Sbjct: 118 LDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAEHPDGISGAMARIE 177 Query: 186 QVKSHHQQPQDWDTLSMGMSGDLQQAIAAGASIVRIGTALFGAR 229 Q + S+ S A VR G L+GA Sbjct: 178 QAAEGLECR-----RSLSNSAATLWHPEAHFDWVRPGIILYGAS 216
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 35.2 bits (81), Expect = 0.002 Identities = 26/217 (11%), Positives = 71/217 (32%), Gaps = 20/217 (9%) Query: 500 QKLKQAQQ-IRLNQLDTTQQKIQ---RYFELKNEMFTLQSQFETVNQQYQEFEQSTQKTE 555 + +++ ++L L ++ + + E Q + + + + + E Sbjct: 116 ESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQI--LSRSIELNKLPELKLPDE 173 Query: 556 QDYQSAKNEREKLQQMLQQQRLLHAE--------NIEHLRAELKHGEACLVCGSIEHPYR 607 +Q+ E L +++ + N++ RAE A + Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 608 DDESQISKALYELQQQQEQQAIQQEQQCFKLWQNMQQQFTQSQTQHKQLQHDLQQLREKL 667 +L Q + ++QE + + ++ +Q + Q++ ++ +E+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLE----QIESEILSAKEEY 289 Query: 668 NGHDQQLQQHLLQSNIQLNFNLNEQDITAQLQALTLD 704 Q + +L Q N+ +T +L Sbjct: 290 QLVTQLFKNEILDKLRQTTDNIGL--LTLELAKNEER 324 Score = 32.9 bits (75), Expect = 0.008 Identities = 20/133 (15%), Positives = 52/133 (39%), Gaps = 9/133 (6%) Query: 620 LQQQQEQQAIQQEQQCFKLWQNMQQQFTQSQTQHKQLQHDLQQLREKLNGHDQQLQQHLL 679 + +++ + ++ F WQN Q Q + + + + + ++N ++ + + Sbjct: 179 VSEEEVLRLTSLIKEQFSTWQN---QKYQKELNLDKKRAERLTVLARINRYENLSR--VE 233 Query: 680 QSNIQLNFNLNEQDITAQLQALTLDS--FQAHQQLENELQLLNQANKDHYQLTQRIQNTR 737 +S + +L + A+ L ++ +A +L L Q + + Q Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 738 HQL--ETVDQLQQ 748 E +D+L+Q Sbjct: 294 QLFKNEILDKLRQ 306 Score = 32.5 bits (74), Expect = 0.010 Identities = 16/121 (13%), Positives = 45/121 (37%), Gaps = 7/121 (5%) Query: 631 QEQQCFKLWQNMQQQFTQSQTQHKQLQHDLQQLREKLNGHDQQLQQHLLQSNIQLNFNLN 690 E++ +L +++QF+ Q Q Q + +L + R + ++ ++ S + Sbjct: 180 SEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRV------- 232 Query: 691 EQDITAQLQALTLDSFQAHQQLENELQLLNQANKDHYQLTQRIQNTRHQLETVDQLQQQV 750 E+ +L A + + +A + +++ ++ + + Q V Sbjct: 233 EKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLV 292 Query: 751 Q 751 Sbjct: 293 T 293 Score = 31.3 bits (71), Expect = 0.024 Identities = 27/200 (13%), Positives = 62/200 (31%), Gaps = 30/200 (15%) Query: 231 EIAELHTQFQNIQQQVQQLENEKNQFKQQQQWFEQRDKIRNEIDLKQQQYDLQLKAQQAI 290 ++ L + ++ Q L+ Q + Q E+ L + Y + ++ + Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 291 AQDRVLLSQLEIFSEIRPIVFQQQQIQKTLQQLAPHIQQKHNEFHALTTQFQQEKTRYSQ 350 ++ Q +Q Q+ QK L + +K + E+ Sbjct: 186 RLTSLIKEQFS--------TWQNQKYQKELN-----LDKK-----------RAERLTVLA 221 Query: 351 AEQSLHQFQGFEQKHQKELADLRNHLQKREHIKEDYNKTKSRLTQIESQRHPLLAQQQQL 410 E+ L D + L K+ K + +++ + ++ +Q +Q+ Sbjct: 222 RINRYENLSRVEKS---RLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQI 278 Query: 411 EQTIHQLD---IQHTDDLER 427 E I T + Sbjct: 279 ESEILSAKEEYQLVTQLFKN 298
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 47.9 bits (114), Expect = 2e-08 Identities = 26/138 (18%), Positives = 50/138 (36%), Gaps = 24/138 (17%) Query: 7 TILITGASGFIGRHVLPHLLDANYQLFAY-----------TRHIAQRYKHPNLVWI---- 51 L+TGA+GFIG HV LL+A +Q+ + + P + Sbjct: 2 KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDL 61 Query: 52 ---DDLDQIMQ--PLDYVINLAGENIGQSRWTAERKQKLIDSRVDTTTHVYEWLIRQQQK 106 + + + + V R++ E DS + ++ E + K Sbjct: 62 ADREGMTDLFASGHFERVFISPHR--LAVRYSLENPHAYADSNLTGFLNILE--GCRHNK 117 Query: 107 PRRIISASAIGYYGIDET 124 + ++ AS+ YG++ Sbjct: 118 IQHLLYASSSSVYGLNRK 135
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 105 bits (263), Expect = 5e-27 Identities = 69/410 (16%), Positives = 143/410 (34%), Gaps = 66/410 (16%) Query: 19 AKRKKLLSIFALVIVIVAILYAIWFFFFNHTVSTDNAYVGAETAQITSMVTGQVAEIRVH 78 ++R +L++ F + +++A + ++ + + +I + V EI V Sbjct: 54 SRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVK 113 Query: 79 DTQQVHKGDILAQVDPR--DAQIALSQAQAMLAKAQRQYRQTEANSKSLN---------- 126 + + V KGD+L ++ +A +Q+ + A+ ++ Q + S LN Sbjct: 114 EGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDE 173 Query: 127 --------------------------SQVFVSDDGIASAQAQVGKAQADYNNAI------ 154 +Q + + + +A+ A N Sbjct: 174 PYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVE 233 Query: 155 -EELKRRQTLEQSGAISKEELSTAQTAAQTAKAALDVAKAAVSQAQSSRKAAQSNLAANQ 213 L +L AI+K + + A L V K+ + Q +S +A+ Sbjct: 234 KSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVT 293 Query: 214 ALIQ----GASENSAPDVLSAEANVQQAQLDLERTVIRSPVDGVITGRNIQ-VGQRVAPG 268 L + + ++ + + + + +VIR+PV + + G V Sbjct: 294 QLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTA 353 Query: 269 SVLMKIVPLSA-LYVDANFKESQLSKVRVGQAATLTSDLYGSDVEYHGKVIGFSGGTGSA 327 LM IVP L V A + + + VGQ A + + + +G ++G Sbjct: 354 ETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF--PYTRYGYLVG-------K 404 Query: 328 FALIPAQNATGNWIKVVQRLPVRIALDPKELAEH----PLRVGLSMDASI 373 I + +V V I+++ L+ PL G+++ A I Sbjct: 405 VKNINLDAIEDQRLGLVFN--VIISIEENCLSTGNKNIPLSSGMAVTAEI 452
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 104 bits (261), Expect = 3e-26 Identities = 86/395 (21%), Positives = 167/395 (42%), Gaps = 16/395 (4%) Query: 34 FMVVLDTTIANVSVPHITGNLAVSASQGTWVVTSYAVAEAICVPLTGWLASRFGTVRVFV 93 F VL+ + NVS+P I + + WV T++ + +I + G L+ + G R+ + Sbjct: 24 FFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL 83 Query: 94 MGLIGFTVFSFLCGLSTS-LEMLVLCRIGQGLSGGPLMPLSQTLLMRIFPQEKHSQAMGL 152 G+I S + + S +L++ R QG L ++ R P+E +A GL Sbjct: 84 FGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGL 143 Query: 153 WAMTTVLGPILGPILGGLISDNLSWHWIFFINIPVGIICVLGTIRLLSVAETETIRVRID 212 +G +GP +GG+I+ + HW + + IP+ I + + L E I+ D Sbjct: 144 IGSIVAMGEGVGPAIGGMIAHYI--HWSYLLLIPMITIITVPFLMKLLKKE-VRIKGHFD 200 Query: 213 AIGLFLLVLWIGALQLMLDLGHERDWFNSSIIVLFAVIAVLGFIVFLIWEMTDRLPVVNL 272 G+ L+ +G + ML F +S + F +++VL F++F+ P V+ Sbjct: 201 IKGIILMS--VGIVFFML--------FTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDP 250 Query: 273 WVFRHRGFTVSVLALSFGFGAFFGSIVLIPQWLQMNLNYTATWAGYLTATMG-FGSLMMS 331 + ++ F + VL FG G + ++P ++ + G + G ++ Sbjct: 251 GLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFG 310 Query: 332 PVVAKLAAKYDPRALASFGLLLLGGVTLMRAFWTSDADFMTLAWPQILQGFAVPFFFIPL 391 + L + P + + G+ L L +F + + + + F + Sbjct: 311 YIGGILVDRRGPLYVLNIGVTFLSVSFLTASF-LLETTSWFMTIIIVFVLGGLSFTKTVI 369 Query: 392 SNLALSSVQPQELASAAGLMNFLRTMAGAIGASIA 426 S + SS++ QE + L+NF ++ G +I Sbjct: 370 STIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIV 404
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 118 bits (297), Expect = 2e-34 Identities = 66/254 (25%), Positives = 114/254 (44%), Gaps = 13/254 (5%) Query: 9 LHGKKIIVTGAARGLGLGFAQAIAEAGAQVIMADILIELVEGEAKQLQQQGLQVQAVGLD 68 + GK +TGAA+G+G A+ +A GA + D E +E L+ + +A D Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 69 LSQPESIQTAVQFAVNTWGGLDGLVNCAALATGVGGKDLTQYDPDLWDRVMTVNVKGTWL 128 + +I G +D LVN A + L+ + W+ +VN G + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEE---WEATFSVNSTGVFN 122 Query: 129 MVQACVPYLKQSQSAKIINIASDTALWGAPKLMAYVASKGAILSMTRSMARELGEFNICV 188 ++ Y+ +S I+ + S+ A + AY +SK A + T+ + EL E+NI Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 189 NTLSPGLTLVE------ATEYVPQER----HDLYVTGRAIQRQQHPQDLNGTALYLLSDL 238 N +SPG T + A E ++ + + TG +++ P D+ L+L+S Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQ 242 Query: 239 ASFVTGQNIPVNGG 252 A +T N+ V+GG Sbjct: 243 AGHITMHNLCVDGG 256
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 37.1 bits (86), Expect = 9e-05 Identities = 75/366 (20%), Positives = 134/366 (36%), Gaps = 32/366 (8%) Query: 54 AKLGWLMTSFLLAYGFSSIFLSFLGDIFNPKKMLFWSVTSWGILMLIMGFTTHYGSMLFL 113 A G L+ + L + L L D F + +L S+ + IM + +L++ Sbjct: 43 AHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATA-PFLWVLYI 101 Query: 114 RVLLGIAEGPLFALAYAIVKQTYTDRQQARA----STMFLLGTPIGAFLGFPITAAVLAK 169 ++ G A+A A + ++AR S F G G P+ ++ Sbjct: 102 GRIVAGITGATGAVAGAYIADITDGDERARHFGFMSACFGFGMVAG-----PVLGGLMGG 156 Query: 170 HDWHTTFFVMAALTLVVMIIIVLGLRNLQL--RKIIEIEDSSKRVNFKGHIANTKLLLKN 227 H FF AAL + + L R+ + E + +F+ T + Sbjct: 157 FSPHAPFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALM 216 Query: 228 RAFWLVCLFNIALMTYLWGLNS-----WVPSYLIQDKGFNLKEFGFYSSLPFIAMLVGEV 282 F+++ L LW + W + G +L FG SL AM+ G Sbjct: 217 AVFFIMQLVGQVPAA-LWVIFGEDRFHWDAT----TIGISLAAFGILHSL-AQAMITG-- 268 Query: 283 VGAVFSDKLGKRAIQVFSGLLVAGISLYVMVLMTDPLLIIAAMSLSSMAWGFGVAAVFAL 342 + +LG+R + G++ G ++ T + M L + + G G+ A+ A+ Sbjct: 269 ---PVAARLGERRA-LMLGMIADGTGYILLAFATRGWMAFPIMVLLA-SGGIGMPALQAM 323 Query: 343 LARVTTADVGATAGGIFNGLANFASAAAPVLIGMIVMQTGSFNLGITFLAVVAIVGSFFL 402 L+R + G L + S P+L I + + G ++A A+ Sbjct: 324 LSRQVDEERQGQLQGSLAALTSLTSIVGPLLFTAIYAASITTWNGWAWIAGAALYL--LC 381 Query: 403 TPLLKR 408 P L+R Sbjct: 382 LPALRR 387
>PF05043#Transcriptional activator Length = 493 Score = 29.5 bits (66), Expect = 0.018 Identities = 15/61 (24%), Positives = 29/61 (47%), Gaps = 3/61 (4%) Query: 3 LERVDLNLLIYLDVLLREK---NVTRAAEQLGVTQPAMSNILRRLRNLFNDPLLIRSSEG 59 L + L L++L K + + AE L T+ A+ + L +++ F D + S+ G Sbjct: 5 LSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKDDLSHVKSAFPDLIFHSSTNG 64 Query: 60 M 60 + Sbjct: 65 I 65
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 715 bits (1848), Expect = 0.0 Identities = 282/1036 (27%), Positives = 497/1036 (47%), Gaps = 32/1036 (3%) Query: 6 LFVHRPVANILLGIAMTLLGILAFFRLPVAALPQVDIPTIVVRANLPGASPESMSATVAT 65 F+ RP+ +L I + + G LA +LPVA P + P + V AN PGA +++ TV Sbjct: 4 FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63 Query: 66 PLERAMMGVSGIKAINSSSSQN-STQVILHFDLDTDINEAAREVQAAINVAMSQLPSGMP 124 +E+ M G+ + ++S+S S + L F TD + A +VQ + +A LP + Sbjct: 64 VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123 Query: 125 SPPEYFKVNPSQSPIFYLALSSR--YLSAGKLYELASNQLKPNLAQTSGVGEVEIDGASM 182 S S + S + + + ++ +K L++ +GVG+V++ GA Sbjct: 124 -QQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFGAQY 182 Query: 183 PAVRIILNPNALISQGISLEQVRDAVKKSNVVQSLGVI------EHQNNRWQVALSTHIK 236 A+RI L+ + L ++ V + +K N + G + Q + T K Sbjct: 183 -AMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 237 DAADFSNLIVHQTAQG-IVRLKDVAEVEDSVENRYVAGFHNGEPAVMIKISRQPNANTIA 295 + +F + + + G +VRLKDVA VE EN V NG+PA + I AN + Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 296 TIEKIKAKLPELNSMIPADAKLTTVMDGSEVIHTGLQEARETLLFSIFLVVVVVVLMLGR 355 T + IKAKL EL P K+ D + + + E +TL +I LV +V+ L L Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 356 LRSAIVPSIAMLVTLVGAISLIYLAGFSFNNLSIMAVIVAIGLVVDDAIVVLENIERHI- 414 +R+ ++P+IA+ V L+G +++ G+S N L++ +++AIGL+VDDAIVV+EN+ER + Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 415 EQGEHPFSAAIQGVREVGFTLVAMNLALIIIFISVLFMGGVIERLFREFSLTLVFIVVVS 474 E P A + + ++ LV + + L +FI + F GG ++R+FS+T+V + +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 475 VFVSLILTPSLSARCLQSI---NVQNRQPLYDYSQRMMHGLTRHYIHSLQWIIRHTYLVI 531 V V+LILTP+L A L+ + + +N+ + + HY +S+ I+ T + Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 532 LLWLGAIIGSVYVYQSLPKRILPEQDTGRIESFIRGDDGFSFQIMQPKIATFSQSLLKDP 591 L++ + G V ++ LP LPE+D G + I+ G + + Q + + LK+ Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 592 A--IKDVIGTSG-GAGGTTNSFFM--VSLKPKAEREGK--TTREIAERIRQNAPWIAGA- 643 ++ V +G G + M VSLKP ER G + + R + I Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 644 IFSARVQQDLELDDPFSGNSGQDYLLLLQSDDVALLRKWAPKVAEAIQKLP-ELEEVETL 702 + + +EL + L+ L + ++ + P L V Sbjct: 662 VIPFNMPAIVELG---TATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPN 718 Query: 703 GDEGAQHVTLDINREAARRLGVDVESISSVLNNSFSQRQISTIYDQTNQFHVVMEIDKRF 762 G E L++++E A+ LGV + I+ ++ + ++ D+ + ++ D +F Sbjct: 719 GLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKF 778 Query: 763 TENPEALADIKVPNQNGEYVPLTNFATWSYGITNDRVHRRNQYAAMGIGYVLKQGYTAEQ 822 PE + + V + NGE VP + F T + + R+ R N +M I G ++ Sbjct: 779 RMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGD 838 Query: 823 AEYAIRSVLPQVMLPNQIFVATDKDVEAESLQAGLSTPMLLVTVIALIYIVLGITYESMV 882 A + ++ + LP I E +G P L+ ++++ L YES Sbjct: 839 AMALMENLASK--LPAGIGYDWTGMSYQER-LSGNQAPALVAISFVVVFLCLAALYESWS 895 Query: 883 HPLTILSTIPAIALGGLLTLWLFNFEFTLIALLGMFLLIGIVVKNAILLIDFTLQ-QRRL 941 P++++ +P +G LL LFN + + ++G+ IG+ KNAIL+++F + Sbjct: 896 IPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKE 955 Query: 942 GKTALESVVSAATLRFRPILMTNTAALLGAIPLALSTTEGSELRQPLGLVIVGGLALGQL 1001 GK +E+ + A +R RPILMT+ A +LG +PLA+S GS + +G+ ++GG+ L Sbjct: 956 GKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATL 1015 Query: 1002 LTLYTTPVMYLVLEKL 1017 L ++ PV ++V+ + Sbjct: 1016 LAIFFVPVFFVVIRRC 1031 Score = 85.7 bits (212), Expect = 6e-19 Identities = 71/511 (13%), Positives = 169/511 (33%), Gaps = 41/511 (8%) Query: 2 NIFALFVHRPVANILLGIAMTLLGILAFFRLPVAALPQVDIPTIVVRANLP-GASPESMS 60 N + +L+ + ++ F RLP + LP+ D + LP GA+ E Sbjct: 528 NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQ 587 Query: 61 ATVATPLERAM----------MGVSGIKAINSSSSQNSTQVILH-FDLDTDINEAAREVQ 109 + + + V+G + + V L ++ +A V Sbjct: 588 KVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVI 647 Query: 110 AAINVAMSQLPSGM---PSPPEYFKVNPSQSPIFYLALSSRYLSAGKLYELASNQLKPNL 166 + + ++ G + P ++ + F L + L L + + L Sbjct: 648 HRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFEL-IDQAGLGHDALTQARNQLLGMAA 706 Query: 167 AQTSGVGEVEIDG-ASMPAVRIILNPNALISQGISLEQVRDAVKKSNVVQSLGVIEHQNN 225 + + V +G ++ ++ + G+SL + + + + + Sbjct: 707 QHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGR 766 Query: 226 RWQVAL---STHIKDAADFSNLIVHQTAQGIVRLKDVAEVED----SVENRYVAGFHNGE 278 ++ + + D L V +V RY NG Sbjct: 767 VKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERY-----NGL 821 Query: 279 PAVMIKISRQPNANT---IATIEKIKAKLPELNSMIPADAKLTTVMDGSEVIHTGLQEAR 335 P++ I+ P ++ +A +E + +KLP S +A Sbjct: 822 PSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGY--------DWTGMSYQERLSGNQAP 873 Query: 336 ETLLFSIFLVVVVVVLMLGRLRSAIVPSIAMLVTLVGAISLIYLAGFSFNNLSIMAVIVA 395 + S +V + + + + + + + +VG + L + ++ ++ Sbjct: 874 ALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTT 933 Query: 396 IGLVVDDAIVVLENI-ERHIEQGEHPFSAAIQGVREVGFTLVAMNLALIIIFISVLFMGG 454 IGL +AI+++E + ++G+ A + VR ++ +LA I+ + + G Sbjct: 934 IGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNG 993 Query: 455 VIERLFREFSLTLVFIVVVSVFVSLILTPSL 485 + ++ +V + +++ P Sbjct: 994 AGSGAQNAVGIGVMGGMVSATLLAIFFVPVF 1024 Score = 78.0 bits (192), Expect = 1e-16 Identities = 95/517 (18%), Positives = 191/517 (36%), Gaps = 29/517 (5%) Query: 524 IRHTYLVILLWLGAIIGSVYVYQSLPKRILPEQDTGRIESFIRGDDGFSFQIMQPKIAT- 582 IR +L + ++ LP P + G Q +Q + Sbjct: 6 IRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYP-GADAQTVQDTVTQV 64 Query: 583 FSQSLLKDPAIKDVIGTSGGAGGTTNSFFMVSLKPKAEREGKTTREIAERIRQNAPWIAG 642 Q++ + + TS AG T ++ + + + ++ +++ P + Sbjct: 65 IEQNMNGIDNLMYMSSTSDSAGSVT---ITLTFQSGTDPD-IAQVQVQNKLQLATPLLPQ 120 Query: 643 AIFSARVQQDLELDDPFSGNSGQDYLLLLQSDDVAL----LRKWAPK-VAEAIQKLPELE 697 + + + + SD+ + + V + + +L + Sbjct: 121 EVQQQGISVEKSSSSYL-------MVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 698 EVETLGDEGAQHVTLDINREAARRLGV-DVESISSVLNNSFSQRQI-STIYDQTNQFHVV 755 +V+ G + A + LD + +L DV + V N+ + Q+ T Q + Sbjct: 174 DVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNAS 233 Query: 756 MEIDKRFTENPEALADIKVP-NQNGEYVPLTNFATWSYGITNDR-VHRRNQYAAMGIGYV 813 + RF NPE + + N +G V L + A G N + R N A G+G Sbjct: 234 IIAQTRFK-NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 814 LKQGYTAEQAEYAIRSVLPQV--MLPNQIFVATDKDVEAESLQAGLSTPML-LVTVIALI 870 L G A AI++ L ++ P + V D +Q + + L I L+ Sbjct: 293 LATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYD-TTPFVQLSIHEVVKTLFEAIMLV 351 Query: 871 YIVLGITYESMVHPLTILSTIPAIALGGLLTLWLFNFEFTLIALLGMFLLIGIVVKNAIL 930 ++V+ + ++M L +P + LG L F + + + GM L IG++V +AI+ Sbjct: 352 FLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIV 411 Query: 931 LIDFTLQQRRLGKTALESVVSAATLRFRPILMTNTAALLGA-IPLALSTTEGSELRQPLG 989 +++ + K + + + + L+ L IP+A + + Sbjct: 412 VVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFS 471 Query: 990 LVIVGGLALGQLLTLYTTPVM-YLVLEKLAQIFKKFK 1025 + IV +AL L+ L TP + +L+ ++ + K Sbjct: 472 ITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK 508
>PHPHTRNFRASE#Phosphoenolpyruvate-protein phosphotransferase signature. Length = 572 Score = 28.2 bits (63), Expect = 0.039 Identities = 19/95 (20%), Positives = 31/95 (32%), Gaps = 8/95 (8%) Query: 114 PNITETLKAARTLIDDGFEIMVYTSDDPIVAKELESMGCVAIMPLGSLIGSGLGILNPHT 173 +TE ++ +I DG E +V + K E Sbjct: 207 KEVTEKIQHGDMVIVDGIEGIVIVNPTEEEVKAYEEKRAAFEKQKQEWAKL------VGE 260 Query: 174 ISIIKENAKVPVLVDAGVGTASDAAIAMELGCDGV 208 S K+ A V + A +GT D + G +G+ Sbjct: 261 PSTTKDGAHVELA--ANIGTPKDVDGVLANGGEGI 293
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 116 bits (291), Expect = 2e-30 Identities = 80/373 (21%), Positives = 133/373 (35%), Gaps = 80/373 (21%) Query: 22 IGIDLGTTHSLVATVLSGQSKVLQD------EKGRVLFPSIVHYAEQSIEYGDDAKPFIT 75 + IDLGT ++L+ + GQ VL + + R P V G DAK + Sbjct: 13 LSIDLGTANTLIY--VKGQGIVLNEPSVVAIRQDRAGSPKSV------AAVGHDAKQMLG 64 Query: 76 TDPKNSIISVKRFMGRSKADIKFQHPYVLVGNDNEMPAFETAQGRKTPVEISAAILNQLK 135 P N I +++ AD F + ++ + Q+ Sbjct: 65 RTPGN-IAAIRPMKDGVIAD------------------FFVTE------KMLQHFIKQVH 99 Query: 136 IRAEESLKNPINGAVITVPAYFDEAQRQATRDAAQLAGLNVLRLLNEPTAAAIAYGLDQE 195 S P ++ VP + +R+A R++AQ AG + L+ EP AAAI GL Sbjct: 100 SN---SFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVS 156 Query: 196 NQLSSDRNYVIYDLGGGTFDVSILRFSQGVFEVLATGGHTALGGDDLDRLIVKWAKKQLH 255 S ++ D+GGGT +V+++ + V +GGD D I+ + ++ Sbjct: 157 EATGS----MVVDIGGGTTEVAVISLNGVV-----YSSSVRIGGDRFDEAIINYVRRNYG 207 Query: 256 IESLDDHEYAAFLVAARTAKEQLSEQQSVYFKA---------------LDHKLELNRDTF 300 L+ TA+ E S Y + LN + Sbjct: 208 S-----------LIGEATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEI 256 Query: 301 ESIIQIALDKTISVCKRVLRDAK--LSLDEIEK-VVLVGGSTRSYAVQNVVRQVFNQEPL 357 +Q L +S L L+ D E+ +VL GG + ++ + + Sbjct: 257 LEALQEPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVV 316 Query: 358 CTINPDEVVAIGA 370 +P VA G Sbjct: 317 VAEDPLTCVARGG 329
>FERRIBNDNGPP#Ferrichrome-binding periplasmic protein signature. Length = 296 Score = 27.2 bits (60), Expect = 0.043 Identities = 7/37 (18%), Positives = 18/37 (48%) Query: 133 ADWKQWLAKPETPEEAVASKRRIAPLLEKIDQQRSQI 169 +++ W+++P P+ + R P LE + + + Sbjct: 63 INYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSF 99
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 294 bits (755), Expect = 2e-95 Identities = 104/323 (32%), Positives = 168/323 (52%), Gaps = 37/323 (11%) Query: 314 IAKLSKILHSDVPILITGATGSGKDHLARQIHEFAT-KDQAFISINCAAIPEHLLESELF 372 L++++ +D+ ++ITG +G+GK+ +AR +H++ ++ F++IN AAIP L+ESELF Sbjct: 150 YRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELF 209 Query: 373 GYEAGAFTGASAKGKRGLIELAHQGILFLDEIGDLPKHLQAKLLRVLQDQVFYRVGGHKP 432 G+E GAFTGA + G E A G LFLDEIGD+P Q +LLRVLQ + VGG P Sbjct: 210 GHEKGAFTGAQTRST-GRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTP 268 Query: 433 IQSQFKLISATHQDLLAMIDNHDFRSDLYYRICGYQIELPQLKDRPDKI-DIFKTLLA-- 489 I+S ++++AT++DL I+ FR DLYYR+ + LP L+DR + I D+ + + Sbjct: 269 IRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPPLRDRAEDIPDLVRHFVQQA 328 Query: 490 ---NAKIYSWSVNVQEQFEHYDWPGNIRELTHVIQLSAALIAHDSLEHAHLEHLHVPQQR 546 + + E + + WPGN+REL ++++ AL D + +E+ + Sbjct: 329 EKEGLDVKRFDQEALELMKAHPWPGNVRELENLVRRLTALYPQDVITREIIENELRSEIP 388 Query: 547 KVTPQSYLANKPQTSLN-----------------------------QMTKQLVLDILQQE 577 + A S++ +M L+L L Sbjct: 389 DSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGLYDRVLAEMEYPLILAALTAT 448 Query: 578 KGNISQAAKRLNISRTTLYKYLQ 600 +GN +AA L ++R TL K ++ Sbjct: 449 RGNQIKAADLLGLNRNTLRKKIR 471
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 66.4 bits (162), Expect = 8e-14 Identities = 72/411 (17%), Positives = 161/411 (39%), Gaps = 28/411 (6%) Query: 20 HWRVIILSTLIIIFDGYDLVIYGVALPLLMKEWAIDPVTAGFIGSIALFGMMFGALIFGT 79 H +++I ++ F + ++ V+LP + ++ P + ++ + + G ++G Sbjct: 12 HNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 80 IADKLEHLGVSRKKVIAVCIILFSLCTVLCGFSETTTQFSIF-RFLAGVGIGGVMPNVIA 138 ++D+L K+++ II+ +V+ + I RF+ G G V+ Sbjct: 72 LSDQL-----GIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMV 126 Query: 139 LVSEYAPKKFKSFFVTLMFSGYAIGGMTAAFLGSILVPLYGWKIMFMIAGIPLVLLLPLM 198 +V+ Y PK+ + L+ S A+G +G ++ W + +I I ++ + LM Sbjct: 127 VVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLM 186 Query: 199 KVLPESI---DYLVRKKKDETVRFIMTKMVPSYQYQPDHV------FVLNSSNQNQAQAP 249 K+L + + + K I+ M+ + Y + F++ + + P Sbjct: 187 KLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDP 246 Query: 250 VKMIFQEQRAFSTMMFWCSIFMTLIMVYALGNW--LPKLMIEAGYNLSKSLI---FLFSL 304 F + + F + I+ + + + M++ + LS + I +F Sbjct: 247 ----FVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPG 302 Query: 305 NVGGMIGSILGGYLADRY---NVKFVTMGLLLLGAISLSLLSFQFSSVILYILIACAGAA 361 + +I +GG L DR V + + L + ++ S L S + I++ G Sbjct: 303 TMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGL 362 Query: 362 SIGAQIMLLAYMAKFYAPNVRSTGIGWGLGMGRVGAILGPILTGWLLSLQL 412 S + ++ ++ G+ + G + G LLS+ L Sbjct: 363 SF-TKTVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 96.3 bits (239), Expect = 5e-26 Identities = 68/264 (25%), Positives = 111/264 (42%), Gaps = 27/264 (10%) Query: 8 EHKVVIVTGAAQGIGRGVALRIAQEGGCLILAD-RSDLIQAVLAEIKALGALAIAVETDL 66 E K+ +TGAAQGIG VA +A +G + D + ++ V++ +KA A A D+ Sbjct: 7 EGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADV 66 Query: 67 ETYAGAELVVSHAIAEYGRIDVLINNVGGAIWMKPFQEFSEEEIIQEVHRSLFPALWCCR 126 A + + + E G ID+L+ NV G + S+EE + R Sbjct: 67 RDSAAIDEITARIEREMGPIDILV-NVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 127 AVLPEMLKHQQGTIVNVSSIATRGIHRI---PYSASKGGVNALTASLAFEHAQHGIRVNA 183 +V M+ + G+IV V S G+ R Y++SK T L E A++ IR N Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPA-GVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNI 184 Query: 184 VATGGTKAPPRKIPRNAQPLSKSEQVWMQQVVDQTIDRSF---------LGRYGSIDEQV 234 V+ G T+ +W + + + + L + + Sbjct: 185 VSPGSTET------------DMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIA 232 Query: 235 NAITFLASDESSYITGSVLPVGGG 258 +A+ FL S ++ +IT L V GG Sbjct: 233 DAVLFLVSGQAGHITMHNLCVDGG 256
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 253 bits (647), Expect = 5e-82 Identities = 106/430 (24%), Positives = 198/430 (46%), Gaps = 55/430 (12%) Query: 19 PPLPRASLIIWIVGIALVILVVWAWVFKLEEVSTGTGKVIPSSKEQMIQSLDGGILTKLD 78 P R L+ + + LVI + + + ++E V+T GK+ S + + I+ ++ I+ ++ Sbjct: 52 PVSRRPRLVAYFIMGFLVIAFILSVLGQVEIVATANGKLTHSGRSKEIKPIENSIVKEII 111 Query: 79 VKEGDIVQKGQILAQLDPTRFASNVGESQSLLMAAQATSARLRA-----EVNGTP-LAFP 132 VKEG+ V+KG +L +L ++ ++QS L+ A+ R + E+N P L P Sbjct: 112 VKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLP 171 Query: 133 D----------EVKQEPKLVQEETALYNSRRANLE--------------ETVAGLKQALH 168 D EV + L++E+ + + +++ E + + Sbjct: 172 DEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSR 231 Query: 169 LVQQELVMTEPLVAKGAASEVEVLRLKREANDLQNKINDARSS----------------- 211 + + L L+ K A ++ VL + + + N++ +S Sbjct: 232 VEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL 291 Query: 212 ----YYVKAREELSKSNTDVQTQQQVIKGRTDTLNRTVFKAPVRGVVKEITVTTLGGVVP 267 + + ++L ++ ++ + + +V +APV V+++ V T GGVV Sbjct: 292 VTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVT 351 Query: 268 QNGKLMTIVPLDEQLLIEARILPRDIAFIRPGQEALVKITAYDYSIYGGMKGKVTVISPD 327 LM IVP D+ L + A + +DI FI GQ A++K+ A+ Y+ YG + GKV I+ D Sbjct: 352 TAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLD 411 Query: 328 TIRDEVKQDQFYYRVYIRTDSDKLYNKAGKAFNITPGMVATVDIKTGQKTIMDYLLKPF- 386 I D+ + + V I + + L + K ++ GM T +IKTG ++++ YLL P Sbjct: 412 AIEDQ--RLGLVFNVIISIEENCL-STGNKNIPLSSGMAVTAEIKTGMRSVISYLLSPLE 468 Query: 387 NKAKEALRER 396 E+LRER Sbjct: 469 ESVTESLRER 478
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 362 bits (931), Expect = e-125 Identities = 120/347 (34%), Positives = 182/347 (52%), Gaps = 19/347 (5%) Query: 20 PVKPIRAKAIIFSDQNSRKLLNQVETIAPSSASVIIQGESGTGKELIAREIHLKSDRKNK 79 ++ +++ + + + +++I GESGTGKEL+AR +H R+N Sbjct: 130 EDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARALHDYGKRRNG 189 Query: 80 PFLAVNCGALVETLAESELFGYEAGAFTGANKTRAGIFETADGGTLFLDEVGELPLTLQV 139 PF+A+N A+ L ESELFG+E GAFTGA G FE A+GGTLFLDE+G++P+ Q Sbjct: 190 PFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQAEGGTLFLDEIGDMPMDAQT 249 Query: 140 KLLRVLQEKEVVRVGGRKPIPINVRILSGTHVDLRKAVAENKFRLDLYYRLNVVVLNILP 199 +LLRVLQ+ E VGGR PI +VRI++ T+ DL++++ + FR DLYYRLNVV L + P Sbjct: 250 RLLRVLQQGEYTTVGGRTPIRSDVRIVAATNKDLKQSINQGLFREDLYYRLNVVPLRLPP 309 Query: 200 LRERKGDILPLVDFFLSSYSQKLITTKPNISDRARNALLNYSWPGNIRELENNIHYALLV 259 LR+R DI LV F+ ++ + K A + + WPGN+RELEN + + Sbjct: 310 LRDRAEDIPDLVRHFVQQAEKEGLDVK-RFDQEALELMKAHPWPGNVRELENLVRRLTAL 368 Query: 260 SGGKTIDLEHLRFS---------EETGSAVLPDNDLIQEFESILKRLFQEYD-------- 302 I E + E +A + Q E +++ F + Sbjct: 369 YPQDVITREIIENELRSEIPDSPIEKAAARSGSLSISQAVEENMRQYFASFGDALPPSGL 428 Query: 303 -GEAWHIIEDKIVNTAFSSCWNNQVKTAKMLGLSRNVLRNLLSRYNL 348 +E ++ A ++ NQ+K A +LGL+RN LR + + Sbjct: 429 YDRVLAEMEYPLILAALTATRGNQIKAADLLGLNRNTLRKKIRELGV 475
>TATBPROTEIN#Bacterial sec-independent translocation TatB protein signature. Length = 171 Score = 69.3 bits (169), Expect = 8e-18 Identities = 32/104 (30%), Positives = 59/104 (56%), Gaps = 1/104 (0%) Query: 1 MFNISFGELLAFAIIALIILGPEKLPHTLRSVLLKYRAVKNQISKIQNDIENELDLIELK 60 MF+I F ELL II L++LGP++LP +++V RA+++ + +QN++ EL L E + Sbjct: 1 MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQ 60 Query: 61 RVMQE-ELQKIKQNEEQLKQQLALMQQEIENVQTSVSIERKTKA 103 +++ E + +LK + ++Q E+++ S KA Sbjct: 61 DSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKA 104
>PF03544#Gram-negative bacterial tonB protein Length = 243 Score = 83.1 bits (205), Expect = 4e-21 Identities = 46/226 (20%), Positives = 77/226 (34%), Gaps = 12/226 (5%) Query: 49 VLIAIIAVVSAHLGIWYVAKQLPTPALDIHKPEPVVIEIVKPVEPPKVIEPKIPPITEKP 108 V I V + +LP P +P+ + +V P + + PP Sbjct: 22 VCIHGAVVAGLLYTSVHQVIELPAP------AQPISVTMVAPADLEPPQAVQPPPEPVVE 75 Query: 109 KVPPVVEKPKPI-PKQVEQPKPVQKSVEQPKPVAKAVAEPTPQKVAEPVATKEVVAEPVK 167 P P+P V KP K +PKPV K K E Sbjct: 76 PEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVEQPKRDVKPVESRPASPFENTAPA 135 Query: 168 KVAEPVKASDDNLPVTEAKGYAGYLSNPAPEYPEQALERGWEGSVILRVKVLANGSPDTV 227 + + + PVT LS P+YP +A EG V ++ V +G D V Sbjct: 136 RPTSSTATAATSKPVTSVASGPRALSRNQPQYPARAQALRIEGQVKVKFDVTPDGRVDNV 195 Query: 228 SVKQSSGKKLLDSAAVRTVKQWKFSPALKGKTPVEGWVDVPIHYQL 273 + + + + +++W++ P G + V I +++ Sbjct: 196 QILSAKPANMFEREVKNAMRRWRYEPGKPG-----SGIVVNILFKI 236
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 48.9 bits (116), Expect = 4e-09 Identities = 27/158 (17%), Positives = 63/158 (39%) Query: 20 VGAEQGIGAAVCRRFAQEKFKVYVAGRTLNKVEKVAAAIHRQGGQAVAYVLDAENEQQLQ 79 GA QGIG AV R A + + K+EKV +++ + A A+ D + + Sbjct: 14 TGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDSAAID 73 Query: 80 TLFDHLNDQPEALAAVIHNVGGNIPSIFLQSSLKFFSQMWRSTFLSSVLVAQRSLSIFQK 139 + + + + +++ G P + S + + + ++ Sbjct: 74 EITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSKYMMD 133 Query: 140 QQQGTLIFTGASASLRGKPFFAAFSMGKSALRSYALNL 177 ++ G+++ G++ + + AA++ K+A + L Sbjct: 134 RRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCL 171
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 82.0 bits (202), Expect = 9e-21 Identities = 56/204 (27%), Positives = 87/204 (42%), Gaps = 16/204 (7%) Query: 3 LKGNVVLVTGGASGLGGAVVQRLAEQGARLVIIDLNQSLGEQLARQVSGLF-----VQAD 57 ++G + +TG A G+G AV + LA QGA + +D N E++ + AD Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 58 VTNEEQIDQAFQQAEEFYKKKVRVVVNCAGIGPPGKAIDREGNPLALSTFSKIININLNG 117 V + ID+ + E + ++VN AG+ PG I L+ + ++N G Sbjct: 66 VRDSAAIDEITARIER-EMGPIDILVNVAGVLRPG-LIHS----LSDEEWEATFSVNSTG 119 Query: 118 TFNVLSKFAARLHREAVEGEERGVIINTASVAAFDGQIGQPAYAASKAGVVGMTLPLARE 177 FN + + G I+ S A + AYA+SKA V T L E Sbjct: 120 VFNASRSVSKYMMDR-----RSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLE 174 Query: 178 FARYGIRVMTIAPGIFLTPLLATL 201 A Y IR ++PG T + +L Sbjct: 175 LAEYNIRCNIVSPGSTETDMQWSL 198
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 51.4 bits (123), Expect = 3e-09 Identities = 43/179 (24%), Positives = 65/179 (36%), Gaps = 5/179 (2%) Query: 39 IVCFLIVFVDGIDTAAMGFIAPALAQDWGVDRSQ---LGPVMSAALGGMIIGALVSGPTA 95 IV V +D + + + P L +D G +++ A V G + Sbjct: 8 IVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALS 67 Query: 96 DRFGRKIVLSMSMLVFGGFTLACAYSTNLDSLVIFRFLTGIGLGAAMPNATTLFSEYCPA 155 DRFGR+ VL +S+ A + L L I R + GI GA A ++ Sbjct: 68 DRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDG 126 Query: 156 RIRSLLVTCMFCGYNLGMAIGGFISSWLIPAFGWHSLFLLGGWAPLILMLLVIFFLPES 214 R+ M + GM G + + F H+ F + L F LPES Sbjct: 127 DERARHFGFMSACFGFGMVAGPVLGGLM-GGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Score = 31.3 bits (71), Expect = 0.008 Identities = 38/155 (24%), Positives = 62/155 (40%), Gaps = 11/155 (7%) Query: 272 KGTVLLWVTYFMGLVMIYLLTSWLPTLMRETGASLERAAFLG---GLFQFGGVLSALFIG 328 + +++ T + V I L+ LP L+R+ S + A G L+ A +G Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 329 WAMDRFNPNRIIAGFYLAAGIFAVIVGQSLSNPTLLALFI--LCAGIAVNGAQSSMPV-L 385 DRF ++ A + I+ + P L L+I + AGI GA ++ Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATA---PFLWVLYIGRIVAGIT--GATGAVAGAY 119 Query: 386 SARFYPTQCRATGVAWMSGIGRFGAVFGAWIGAVL 420 A RA +MS FG V G +G ++ Sbjct: 120 IADITDGDERARHFGFMSACFGFGMVAGPVLGGLM 154
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 34.4 bits (79), Expect = 7e-04 Identities = 63/346 (18%), Positives = 132/346 (38%), Gaps = 30/346 (8%) Query: 62 PLIPFAQQRLHLNH---ADFGLLLLCTGLGAILAMPTTGLLIYRLGCKTLIAFALILLLT 118 P++P + L ++ A +G+LL L P G L R G + ++ +L Sbjct: 26 PVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAV 85 Query: 119 LLPVLALGTTALTMAVILFFFGTAAGSLGVAVNFQAVIVEKNSEKPMMSGFHGMC----- 173 ++A + + G + VA + A I E+ GF C Sbjct: 86 DYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT-DGDERARHFGFMSACFGFGM 144 Query: 174 ----SLGGLIGVMSVTALLAFGVTPFVSIISISMILVLIGLLTVPYALSAHQQKNTSQDD 229 LGGL+G S A PF + +++ + L G +P + ++ + Sbjct: 145 VAGPVLGGLMGGFSPHA-------PFFAAAALNGLNFLTGCFLLPESHKGERRPLRREAL 197 Query: 230 SHQSIDTAKKRPTLLVILIGLICFISFLSEGAAMDWSGIYLTTQYSMNAAYAGLGYTFFA 289 + + + T++ L+ + + + + A W I+ ++ +A G+ F Sbjct: 198 NPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWV-IFGEDRFHWDATTIGISLAAFG 256 Query: 290 I--AMTSGRLFGQKALHLLGENKLINSSVI---CAFIGLATIVVAPHWIFVLIGYALLGL 344 I ++ + G LGE + + +I +I LA +++ A G+ Sbjct: 257 ILHSLAQAMITG-PVAARLGERRALMLGMIADGTGYILLAFATRGWMAFPIMVLLASGGI 315 Query: 345 GSANIVPIMFSRLGKQSTMQKAAALSCVSTMAYTGSLTGPALVGVI 390 G + ++ ++ ++ Q +L+ ++++ S+ GP L I Sbjct: 316 GMPALQAMLSRQVDEERQGQLQGSLAALTSL---TSIVGPLLFTAI 358
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 30.6 bits (69), Expect = 0.012 Identities = 36/263 (13%), Positives = 93/263 (35%), Gaps = 19/263 (7%) Query: 47 GGLVTLFLVGAMLASLIFAPIFNRFNPKWPVIIGFLSACFAFYLASKNTQFSVLAILHLI 106 G L+ L+ + + + + +RF + +++ A + + + VL I ++ Sbjct: 46 GILLALYALMQFACAPVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIV 105 Query: 107 GGFSAG---LALSFTHGTMGRSLNPHRLFGFAGLALGIFAILFLAGSL--NLIRNFGGAT 161 G + +A ++ R FGF F +AG + L+ F Sbjct: 106 AGITGATGAVAGAYIADITDGDERA-RHFGFMS---ACFGFGMVAGPVLGGLMGGFSPHA 161 Query: 162 LFLILASIMAIAACVAFLFYPQVNK------KQENIQFETYHRPKFSKYIWCCIFGISLL 215 F A++ + P+ +K ++E + R + + + + Sbjct: 162 PFFAAAALNGLNFLTGCFLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFI 221 Query: 216 A-MTNSMNVSFYERIGIAR-GFGESSVALTLIIYGIV-SIFPAPIAAFTQKYFNPLIVIC 272 + + + + G R + +++ ++L +GI+ S+ A I + Sbjct: 222 MQLVGQVPAALWVIFGEDRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRALM 281 Query: 273 IGPVFQAI-FSLVLTHSHNYVLY 294 +G + + L+ + ++ + Sbjct: 282 LGMIADGTGYILLAFATRGWMAF 304
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 55.7 bits (134), Expect = 2e-10 Identities = 74/414 (17%), Positives = 155/414 (37%), Gaps = 40/414 (9%) Query: 21 HLSVVFWCTLINICDGYDLVIYGVVLPRLMEQWSLTSVQAGMLASTAMCGMLVGALSCGI 80 H ++ W +++ + ++ V LP + ++ + + M +G G Sbjct: 12 HNQILIWLCILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGK 71 Query: 81 LADKFGRKRVLLLCVFFLSTFTLLGSFASTPTEFAIL-RFLAGLGIGGAMPNVVALTSEY 139 L+D+ G KR+LL + +++G + I+ RF+ G G V+ + + Y Sbjct: 72 LSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARY 131 Query: 140 SPKKSRVTMVSIMSCGYAVGAIISALVGSILVERFGWQIMFILAGIPLLFIPIIWKYLPE 199 PK++R ++ A+G + +G ++ W + ++ I ++ +P + K L + Sbjct: 132 IPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKK 191 Query: 200 ------------------SLVFNVKKNNTEKAHALIAKVDPTVLVSQHTKLVLNESLEKA 241 +VF + + LI V ++ +H + V + ++ Sbjct: 192 EVRIKGHFDIKGIILMSVGIVFFMLFTTSYSISFLIVSVLSFLIFVKHIRKVTDPFVDPG 251 Query: 242 YGSRRVLFQEGRAAGTLKFWIAFFMCLLV-----VYALSSWLPKLMYNAGYPLGKSILFL 296 G G + +A F+ ++ V+ LS+ +G I+F Sbjct: 252 LGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLST----------AEIGSVIIFP 301 Query: 297 LAMNVGGIIGGTTSGMLADKFKIKPVVISLFCIAALSLIALGF---NTSAIILYTLVAVA 353 M+V II G G+L D+ V+ ++S + F TS + +V V Sbjct: 302 GTMSV--IIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVL 359 Query: 354 GASIQGASILLYSYVAQFYPLVANSTGIGWASAIGRTGAIMGPILAGMLLVLNL 407 G +++ + A + G+ + G + G LL + L Sbjct: 360 GGLSFTKTVISTIVSSSLKQQEAGA-GMSLLNFTSFLSEGTGIAIVGGLLSIPL 412
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 114 bits (286), Expect = 7e-33 Identities = 69/253 (27%), Positives = 122/253 (48%), Gaps = 9/253 (3%) Query: 4 LKGKVALVTGGGRGIGRAICEAMAKEGARVGVLDLKHEVALESVNAIQAQGGEAIALVGN 63 ++GK+A +TG +GIG A+ +A +GA + +D E + V++++A+ A A + Sbjct: 6 IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65 Query: 64 VAQREDLINAVTTLKQQFGAPDILVNNAMWNRYGPLMDQNESMIDRMIDVGLKGVVWGYQ 123 V + ++++ G DILVN A R G + ++ + V GV + Sbjct: 66 VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125 Query: 124 AVLNDMIKQGGGSIINIGSPSSVLAMRHGVMYSAIKSAVSGLTRSGAAEFGEFNIRVNAI 183 +V M+ + GSI+ +GS + + Y++ K+A T+ E E+NIR N + Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185 Query: 184 APSSTPTEGAKLVVSEEAWERRRQR---------IPLGRLCAADDVAKAAVFLASDDSSF 234 +P ST T+ + ++E + + IPL +L D+A A +FL S + Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245 Query: 235 ISGDVLFVDGAST 247 I+ L VDG +T Sbjct: 246 ITMHNLCVDGGAT 258
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 142 bits (360), Expect = 3e-41 Identities = 86/251 (34%), Positives = 128/251 (50%), Gaps = 12/251 (4%) Query: 275 RVVVITGAAQGIGRAIAEKFAAQGDRLILLDLNQEPLEKLRETLAGEHL---SFCVDISD 331 ++ ITGAAQGIG A+A A+QG + +D N E LEK+ +L E +F D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 332 EQQVKQVFHSIQKLYSEIDVLVNNAGIAEQFLPLEQQSVEAIEKLFDINLNGAFCCIREC 391 + ++ I++ ID+LVN AG+ + + S E E F +N G F R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVL-RPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 392 LNAMQ-HKAGVVINMGSINSHLAFSPRHAYGASKAAIEMLSRCLTAELAPQGIRVLTLCP 450 M ++G ++ +GS + + + AY +SKAA M ++CL ELA IR + P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 451 GYIQTPGVVQL-------EQSGRINVENIRRRIPLGRLGQPEDIAEAAYFLASPQASYIN 503 G +T L EQ + ++E + IPL +L +P DIA+A FL S QA +I Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 504 GAAVYVDGGWT 514 + VDGG T Sbjct: 248 MHNLCVDGGAT 258 Score = 126 bits (318), Expect = 3e-35 Identities = 83/249 (33%), Positives = 117/249 (46%), Gaps = 12/249 (4%) Query: 6 KVAIVTGANGGIGRVICQSLASAHYLIAGLDREGIDLERNMSQLGTEHR---AYVCDLAD 62 K+A +TGA GIG + ++LAS IA +D LE+ +S L E R A+ D+ D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 63 DQQIQRVVKEIAAHYGHIDLIVNNAAIGPTMSATIDTSLDEFKQAMSVNWMGPLQLIRQA 122 I + I G ID++VN A + S +E++ SVN G R Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGV-LRPGLIHSLSDEEWEATFSVNSTGVFNASRSV 127 Query: 123 LPWMPIH-GAAIVNIASLAGVVSNPKRNAYSASKAAMISLTRSLACELAHKQIRVNAIAP 181 +M +IV + S V AY++SKAA + T+ L ELA IR N ++P Sbjct: 128 SKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187 Query: 182 GYVRTNMVAELETSG-------KVDLHLVRQRIPMGRLARPEEIAHVVTFLGSEQARYIT 234 G T+M L K L + IP+ +LA+P +IA V FL S QA +IT Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247 Query: 235 GSIVPVDGG 243 + VDGG Sbjct: 248 MHNLCVDGG 256
>cloacin#Cloacin signature. Length = 551 Score = 52.4 bits (125), Expect = 2e-09 Identities = 46/133 (34%), Positives = 61/133 (45%), Gaps = 16/133 (12%) Query: 184 SGTGGSSGGTGNCTVSGNTINCVGANGGSGGDG-GSGANGGAGAGG----GAGGSGGSGS 238 SG G TG + SGN NGG G G G GA+ G+G GGSG Sbjct: 2 SGGDGRGHNTGAHSTSGNI------NGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIH 55 Query: 239 GGGNGGAGGSGGAGGSGGAGGSGGAGGSASVTVNFDAAGIISAVNALGTSLKTSITDLKT 298 GG G G GG G SGG G+GG + + V F +S A G ++ S Sbjct: 56 WGGGSGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPA-LSTPGAGGLAVSIS----AG 110 Query: 299 SLTSAINDVKSSL 311 +L++AI D+ ++L Sbjct: 111 ALSAAIADIMAAL 123 Score = 52.4 bits (125), Expect = 2e-09 Identities = 43/127 (33%), Positives = 62/127 (48%), Gaps = 9/127 (7%) Query: 178 SGGDSGSGTGGSSGGTGNCTVSGNTINCVGANGGSGGDGGSGAN----GGAGAGGGAGGS 233 SGGD G+ +GN ++G G S G G S N GG+G+G GG Sbjct: 2 SGGDGRGHNTGAHSTSGN--INGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGG 59 Query: 234 GGSGSGGGNGGAGGSGGAGGSGGAGGSGGAGGSASVTVNFDAAGIISAVNALGTSLKTSI 293 G G+GGGNG +GG G GG+ A + A G +++ A G+ AV+ +L +I Sbjct: 60 SGHGNGGGNGNSGGGSGTGGNLSAVAAPVAFGFPALSTP-GAGGL--AVSISAGALSAAI 116 Query: 294 TDLKTSL 300 D+ +L Sbjct: 117 ADIMAAL 123 Score = 32.0 bits (72), Expect = 0.005 Identities = 27/85 (31%), Positives = 30/85 (35%), Gaps = 11/85 (12%) Query: 167 GGDGGSGGDSGSGGDS-------GSGTGGSSGGTGNCTVSGNTINCVGANGGSGGDGGSG 219 G G G GSG S GSG+G GG G N G +G G Sbjct: 26 GLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVA 85 Query: 220 ANGGAG----AGGGAGGSGGSGSGG 240 A G + GAGG S S G Sbjct: 86 APVAFGFPALSTPGAGGLAVSISAG 110 Score = 30.5 bits (68), Expect = 0.018 Identities = 28/101 (27%), Positives = 32/101 (31%), Gaps = 7/101 (6%) Query: 164 NFQGGDGGSGGDSGSGGDSGSGT------GGSSGGTGNCTVSGNTINCVGANGGSGGDGG 217 N GG G G G+ SG + GGS G SG+ N G G G Sbjct: 19 NINGGPTGLGVGGGASDGSGWSSENNPWGGGSGSGIHWGGGSGHGNGGGNGNSGG-GSGT 77 Query: 218 SGANGGAGAGGGAGGSGGSGSGGGNGGAGGSGGAGGSGGAG 258 G A G S G G S GA + A Sbjct: 78 GGNLSAVAAPVAFGFPALSTPGAGGLAVSISAGALSAAIAD 118 Score = 28.9 bits (64), Expect = 0.046 Identities = 13/42 (30%), Positives = 16/42 (38%) Query: 152 PNTDTKPSTPVPNFQGGDGGSGGDSGSGGDSGSGTGGSSGGT 193 P S G G GG+ SGG SG+G S+ Sbjct: 45 PWGGGSGSGIHWGGGSGHGNGGGNGNSGGGSGTGGNLSAVAA 86
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 68.5 bits (167), Expect = 1e-16 Identities = 30/181 (16%), Positives = 66/181 (36%), Gaps = 10/181 (5%) Query: 1 MSKKDDIINTALRLFNSNSYNSVGIDRIILESGVAKMTFYKYFPSKAKLIEECLNQRNMN 60 + I++ ALRLF+ +S + I +GV + Y +F K+ L E N Sbjct: 10 QETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSESN 69 Query: 61 LQESLTASLEACDPNSPLDRIKAIYMWYSAWFHTDD----FNGCMFQK--AVEEIFKIYP 114 + E P PL ++ I + T++ +F K V E+ + Sbjct: 70 IGELELEYQAKF-PGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFVGEMAVVQQ 128 Query: 115 STIKPAIEYKEWLTERILELLDQMKIK---NPEHLATLLVSILDGMTMHAQIDKHSVNIN 171 + +E + + + + ++ + A ++ + G+ + S ++ Sbjct: 129 AQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLFAPQSFDLK 188 Query: 172 E 172 + Sbjct: 189 K 189
>ARGREPRESSOR#Bacterial arginine repressor signature. Length = 149 Score = 25.6 bits (56), Expect = 0.034 Identities = 11/49 (22%), Positives = 24/49 (48%), Gaps = 3/49 (6%) Query: 47 EEKTNITQPTLSQQLMMLRKSDVVHTRRDGKQIFYSIKDEKLIIVLSTL 95 ++ N+TQ T+S+ +++ +V + YS+ ++ LS L Sbjct: 31 KDGYNVTQATVSR---DIKELHLVKVPTNNGSYKYSLPADQRFNPLSKL 76
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 66.2 bits (161), Expect = 4e-15 Identities = 48/197 (24%), Positives = 87/197 (44%), Gaps = 16/197 (8%) Query: 5 KTILITGASSGLGAGMAKEFAKKGYNLA---ICARRLERLETLKTELERHYDVKIIAKSL 61 K ITGA+ G+G +A+ A +G ++A +LE++ + RH + A Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAE----AFPA 64 Query: 62 DVTNYDQVFEVFNAFEQEFGQLDRIIVNAGIGEGRRVGKGH---FDINRKTAETNFISAL 118 DV + + E+ E+E G +D ++ AG+ R G H + T N Sbjct: 65 DVRDSAAIDEITARIEREMGPIDILVNVAGV---LRPGLIHSLSDEEWEATFSVNSTGVF 121 Query: 119 AQCEAAVEIFRKQNSGHLVVISSMSAMRGLPK-HLSTYAASKAGVAHLAEGIRAELIDTP 177 + + + SG +V + S A G+P+ ++ YA+SKA + + EL + Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPA--GVPRTSMAAYASSKAAAVMFTKCLGLELAEYN 179 Query: 178 IKVSTIFPGYIRTELNQ 194 I+ + + PG T++ Sbjct: 180 IRCNIVSPGSTETDMQW 196
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 112 bits (282), Expect = 9e-31 Identities = 63/348 (18%), Positives = 135/348 (38%), Gaps = 43/348 (12%) Query: 2 ILVTGGLGFLGSHIALSLLAQGQEVILVDNLANASLQTLE--RLEYISGMYIPFVKVDVR 59 LVTG GF+G H++ LL G +V+ +DNL + +L+ RLE ++ F K+D+ Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFHKIDLA 62 Query: 60 NTPALNKVFEQYSIDAVIHTASFKALEESKLKPLEYYNDNVSCIMSLLRSMQRTGVRKLV 119 + + +F + V + A+ S P Y + N++ +++L + ++ L+ Sbjct: 63 DREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHLL 122 Query: 120 HLSSLMVYGKSSSKLTEDEPFDTVYP-----NPYIKSQQMIEEIIRDTFKTDHEWKIAIL 174 + SS VYG L PF T + Y +++ E + T+ + L Sbjct: 123 YASSSSVYG-----LNRKMPFSTDDSVDHPVSLYAATKKANELMAH-TYSHLYGLPATGL 176 Query: 175 RLSNIAGAFEHGVLGEMITQLPKNIIPLAMQVAAMQRDYLELQRQADTTDQTVERSFLHV 234 R + G + P M + + LE + ++R F ++ Sbjct: 177 RFFTVYGPW----------GRPD------MALFKFTKAMLEGKSIDVYNYGKMKRDFTYI 220 Query: 235 LDVCEAVFASLYWLNQQDHCC--------------ESFNIAHNEVTSIQQLLEVISQVTQ 280 D+ EA+ + D +NI ++ + ++ + Sbjct: 221 DDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALG 280 Query: 281 TQINTHDAMYPTEELAQVGANIDKAKQVLNWQPKRTLQQMIEHQWQFY 328 + + ++ + A+ +V+ + P+ T++ +++ +Y Sbjct: 281 IEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWY 328
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 85.1 bits (210), Expect = 8e-22 Identities = 47/188 (25%), Positives = 83/188 (44%), Gaps = 4/188 (2%) Query: 7 NVLLTGASGGIGLALCEALCREGAKVLAVARNIQSLEGLQQKYIGQIKIIRADLLDFQDL 66 +TGA+ GIG A+ L +GA + AV N + LE + + + A D +D Sbjct: 10 IAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRDS 69 Query: 67 NKVIQV----ASQVEGLNLLINAAGVNCFATLDHQSPEQIHQLVQLNVTAPMSLTAGLIA 122 + ++ ++ +++L+N AGV + S E+ +N T + + + Sbjct: 70 AAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVSK 129 Query: 123 KLNAVSEAKIVNVGSIYGSLGFAGYTTYCATKFALRGFSEALRRELADSNIQVLYVAPRA 182 + IV VGS + Y ++K A F++ L ELA+ NI+ V+P + Sbjct: 130 YMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPGS 189 Query: 183 TQTTMNSQ 190 T+T M Sbjct: 190 TETDMQWS 197
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 25.5 bits (56), Expect = 0.031 Identities = 8/25 (32%), Positives = 11/25 (44%) Query: 44 NSEFFPFDLWEKLDHAEINQIIQDE 68 + PF+ + D A I IQ E Sbjct: 111 ALQSRPFEFVRRADPANILNFIQQE 135
>PF04183#IucA / IucC family Length = 580 Score = 176 bits (449), Expect = 4e-50 Identities = 100/522 (19%), Positives = 182/522 (34%), Gaps = 55/522 (10%) Query: 137 KLQQFAQDLAQSIEQFKLSQNCSISYQLCPEQCPSDLFLQFEQYAALRDRPYHPLAKLKD 196 + + QDL ++ + +L Q L P K + Sbjct: 91 TVAEHMQDLYATLLGDLQLLKAR---RGLSASDLINLNADRLQ-CLLSGHPKFVFNKGRR 146 Query: 197 GFSDSEYQNFSPEFQQKIEVRWVAIKKDKLVYGKDILDRDTQQPAHIFLNGAQFDALQME 256 G+ + ++PE+ + W+A+K++ +++ D + D Q ++ +F Sbjct: 147 GWGKEALERYAPEYANTFRLHWLAVKREHMIWRCD-NEMDIHQLLTAAMDPQEFARFSQV 205 Query: 257 LEHKNLDSSYMALPIHAWQFEHVLHKYFKDEIRAHTIMPLQFLSDDFYASSSLRSLVYQK 316 + LD +++ LP+H WQ++ + F + ++ L D + A SLR+L Sbjct: 206 WQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTL-TNA 264 Query: 317 HSPD--HLKLPLAVKSLGSLRYLPIVKMINGQKNQQLLEQAKIHDAVLAQR-LWLCNE-- 371 +KLPL + + R +P + G + L+Q DA L Q + E Sbjct: 265 SRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPA 324 Query: 372 -----NQWWGYLPDQPDLLHPDNLTLFDERPMHLAAQRRQVPAELMDSPYQVIPMASLGQ 426 ++ + L P ++ E P + MA+L + Sbjct: 325 AGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDE-----------SPVLMATLME 373 Query: 427 LTHNNLSVFDLIMKWQYADTTPERIREVFFNLCHDFFEVNLR-----LFRMGLMGEIHGQ 481 NN + + + + F V + L R G+ HGQ Sbjct: 374 CDENNQPLAGAYID-RSGLDAETWLT--------QLFRVVVVPLYHLLCRYGVALIAHGQ 424 Query: 482 NICVVLKAGHFSGFLLRD-HDSVRIHLPWMQQAGLSDPKYLSPHDFRITLYYDTVDELMT 540 NI + +K G LL+D +R+ + S P+ + R++ Y L+ Sbjct: 425 NITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMD-SLPQEVRDVTSRLSADY-----LIH 478 Query: 541 YLQTLGIQVNLSSILESIASYYDLSESELWTVLAQALKQALDHVPFSDQARTQLHDLL-- 598 LQT G V + + + + E + +LA L + P R L L Sbjct: 479 DLQT-GHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHP-QMSERFALFSLFRP 536 Query: 599 -FEQEEWPYKKLIHPLLEQNNRIGSMPSSFGRTCNPLKRALQ 639 + KL P L+ +R +P+ NPL Q Sbjct: 537 QIIRVVLNPVKLTWPDLDGGSR--MLPNYLEDLQNPLWLVTQ 576
>PF04183#IucA / IucC family Length = 580 Score = 380 bits (977), Expect = e-127 Identities = 147/588 (25%), Positives = 253/588 (43%), Gaps = 41/588 (6%) Query: 31 RVEQRVIKQLLQALIFENIV-SSDHKDGVFTIYAYDHEQRPVEYHAFGQYYLSFGLVRLD 89 V +R++ ++L L +E + + D + I ++ F +G + +D Sbjct: 8 LVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPG-----AQW-RFIAERGIWGWLWID 61 Query: 90 QQDVIRQNDAGQQSRASLNLVLDELVHGIEHA-EKRDDFIYEMKRTFIHDLQSQICQRAY 148 +R D ++ +L +L + + + + ++ T + DLQ +R Sbjct: 62 A-QTLRCADEPVLAQT----LLMQLKQVLSMSDATVAEHMQDLYATLLGDLQLLKARRGL 116 Query: 149 S-LPASQYSYEELETYLMEGHPYHPCYKSRVGFSLQDNLRYGVEFAQPIHLVWLAVHRSI 207 S + + L+ L+ GHP K R G+ + RY E+A L WLAV R Sbjct: 117 SASDLINLNADRLQ-CLLSGHPKFVFNKGRRGWGKEALERYAPEYANTFRLHWLAVKREH 175 Query: 208 STVNSSIDIQADDYLNHQLSQQDHLRFSHVLNEHKVNQHDYVWIPVHPWQWENTLVRVFF 267 ++ L + Q+ RFS V E+ ++ H+++ +PVHPWQW+ + F Sbjct: 176 MIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLD-HNWLPLPVHPWQWQQKIATDFI 234 Query: 268 EEISSQQIIYLGRDDQSYVAQQSLRTLTNLKHPEKPYIKLSMSMINTSSSRILATHTAMN 327 + + +++ LG ++AQQSLRTLTN IKL +++ NTS R + Sbjct: 235 ADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAA 294 Query: 328 GPLITDWLQRLINTSEIAQVLDFAILREVHASAVD------FTKLPSSHAKQAYGTIGSL 381 GPL + WLQ++ T IL E A V + P + + +G + Sbjct: 295 GPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYAALARAPYRYQEM----LGVI 350 Query: 382 WRESVHQYLKPQEQAIPLNGIGHVQSDNSLLIQPWLNEYG--AEAWVEQLLKVVIQPILF 439 WRE+ ++LKP E + + + +N L +++ G AE W+ QL +VV+ P+ Sbjct: 351 WRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQLFRVVVVPLYH 410 Query: 440 LLYGEGIGSESHGQNIILVHRNGWPTRIILKDFHDGVRFSPEHLTHPEQLPQLHQLPAEH 499 LL G+ +HGQNI L + G P R++LKDF +R E P++ LP E Sbjct: 411 LLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEE------FPEMDSLPQEV 464 Query: 500 AKANRMSFILTNDLNAVRDMSCVCLFFVALSDIAIGLQQNIDFDEALFWKKTAGVIYDFQ 559 + + FV + L + E F++ A V+ D+ Sbjct: 465 RD------VTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYM 518 Query: 560 DTYPEYSQRFAKFNVFAAEYCVESLTKRRL-FGDSQAQFKQIANPLYP 606 +P+ S+RFA F++F + L +L + D + + N L Sbjct: 519 KKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLED 566
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 104 bits (262), Expect = 2e-26 Identities = 79/398 (19%), Positives = 163/398 (40%), Gaps = 19/398 (4%) Query: 37 LNNSSFNPALVQLMHDFNIGEAAVSWFMVSFLLAMSLSLLLTGFLSQRFGKREVYLGALA 96 LN N +L + +DFN A+ +W +F+L S+ + G LS + G + + L + Sbjct: 28 LNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLLFGII 87 Query: 97 LFVLASAIGGCAK-HYETVLAVRAVQGFASGLMIPLSLGIIFSVTSQQKRGAATGLWGAM 155 + S IG + ++ R +QG + L + ++ ++ RG A GL G++ Sbjct: 88 INCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKAFGLIGSI 147 Query: 156 IMLTLACGPMLGAVLLIWWDWPALFLVNIPFGVLALVLGWIHLPKQTKNRSERFDWFAYS 215 + + GP +G ++ + W +L+ IP + V + L K+ FD Sbjct: 148 VAMGEGVGPAIGGMIAHYIHWS--YLLLIPMITIITVPFLMKLLKKEVRIKGHFDIKGII 205 Query: 216 LLSASIISLLLALSQVKTLSDLESFKFFLLILISILSGLWFWIITRKQQSSLIKWQIFNS 275 L+S I+ +L + +++S+LS L F RK + + + Sbjct: 206 LMSVGIVFFMLFTTSYS----------ISFLIVSVLSFLIFVKHIRKVTDPFVDPGLGKN 255 Query: 276 QGFNYSLFISVMHTTGLFISLLVIPLFIQNTLKLSPIWTGILLMTSALTTSLCSKW-AGE 334 F + + + + ++P +++ +LS G +++ + + + G Sbjct: 256 IPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTMSVIIFGYIGGI 315 Query: 335 FLDQHGAKFLISFGIILTALAFIGLA--LGGHLPLTYLIVCMALHGLGFGLSYMPATTAG 392 +D+ G ++++ G+ +++F+ + L +I+ L GL F + +T Sbjct: 316 LVDRRGPLYVLNIGVTFLSVSFLTASFLLETTSWFMTIIIVFVLGGLSF--TKTVISTIV 373 Query: 393 LNSLSDQELVTQGAAINNLLRRTCSAVAVVIAALYLQI 430 +SL QE G ++ N + I L I Sbjct: 374 SSSLKQQE-AGAGMSLLNFTSFLSEGTGIAIVGGLLSI 410
>PF04183#IucA / IucC family Length = 580 Score = 220 bits (562), Expect = 3e-66 Identities = 111/565 (19%), Positives = 208/565 (36%), Gaps = 49/565 (8%) Query: 58 HIYAPLSYWSQVGRHRLADLPWVERDGKEISIS-ATSLAANLLENLVHQPSKPSLDASSL 116 I P + W + + W+ D + + + LA LL L S + Sbjct: 38 CINLPGAQWRFIAERGIWG--WLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEH 95 Query: 117 LECWIQSRRALFQFLDFRQSDLDRITALKQNFIDSEQALVLGHSMHPSPKSRQGFVQQDW 176 ++ + Q L R+ + L D Q L+ GH K R+G+ ++ Sbjct: 96 MQDLYATLLGDLQLLKARRGL--SASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEAL 153 Query: 177 KVFSPETQSTFKMHFLYVHPDYIAHDNAHNIPVPVQFHHDLQP-YFNDYHRAK--IKEFP 233 + ++PE +TF++H+L V +++ + + + + P F + + Sbjct: 154 ERYAPEYANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDH 213 Query: 234 EYALLPLHPWQARYLKDKTWYQQLLHQHKLIDFGALGWEVKATTSVRTLYSEKAPW--MF 291 + LP+HPWQ + + ++ G G + A S+RTL + Sbjct: 214 NWLPLPVHPWQWQQKIATDFIADFAEGR-MVSLGEFGDQWLAQQSLRTLTNASRRGGLDI 272 Query: 292 KTSMSVAVTNSVRVNLHKECHRGLLSYQLWNDDYLADFRKRHSRLQTLSDPAWIAISING 351 K +++ T+ R + G L+ + + D S L +PA +S G Sbjct: 273 KLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEG 332 Query: 352 ---------DVIDESICILRENPFRTQD---DVTCIASLCQDHPMQEKNRFNEIFASISA 399 + I RENP R +A+L + + + + Sbjct: 333 YAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQP-----LAGAYID 387 Query: 400 RTGQSETDIALNWFDQFLEITFLPLMELYHEFGMAFEAHQQNTLIELEEDWPKTVWFRDN 459 R+G A W Q + +PL L +G+A AH QN + ++E P+ V +D Sbjct: 388 RSGLD----AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDF 443 Query: 460 QGFYYIRERADSILQRFPKLESDGQAVCPQV-------LVDERFRYYFIGNTLFGLINAI 512 QG + + + FP+++S Q V L+ + +F+ T+ I+ + Sbjct: 444 QGDMRL------VKEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFV--TVLRFISPL 495 Query: 513 GASGAVSEHQLIEILQSYLLQAFQKYPDSPLLYTL--LYEETFPYKGNLMTRLYELDELQ 570 V E + ++L + L +K+P + L L+ +L D Sbjct: 496 MVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDG 555 Query: 571 AHISQQSIYVDLKNPLFVKQSELEA 595 + DL+NPL++ E E+ Sbjct: 556 GSRMLPNYLEDLQNPLWLVTQEYES 580
>GPOSANCHOR#Gram-positive coccus surface protein anchor signature. Length = 539 Score = 43.1 bits (101), Expect = 6e-06 Identities = 29/166 (17%), Positives = 55/166 (33%), Gaps = 12/166 (7%) Query: 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDA 776 K + +K +A + +A A + + K K AL + Sbjct: 175 SAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALAARKADLEKAL 234 Query: 777 EKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQE---------IANAIEQAQRIFDIEK 827 E A A+ ++A +A + E+ + + I+ + + Sbjct: 235 EGAMNFSTADSAKIKTLEAEKAALEARQAELEKALEGAMNFSTADSAKIKTLEAEKAALE 294 Query: 828 ASIQAQFDANKISNAQKVQMEKQLEDQLRAIKRNGLEERL-KLEEQ 872 A +++ NA + + + L+ A K LE KLEEQ Sbjct: 295 AEKADLEHQSQVLNANRQSLRRDLDASREAKK--QLEAEHQKLEEQ 338 Score = 36.2 bits (83), Expect = 8e-04 Identities = 35/156 (22%), Positives = 63/156 (40%), Gaps = 4/156 (2%) Query: 717 KKDEKEKKPKKGKSDAEREAEREAKAIADIRYKYATEEEKIQLDLKKALEDIEKAKISDA 776 ++ +K A + ++ I + + A E + +L+KALE + Sbjct: 222 ALAARKADLEKALEGAMNFSTADSAKIKTLEAEKAALEARQA-ELEKALEGAMN-FSTAD 279 Query: 777 EKAQLKVKAEKVASDKIKALRAEQFEKIKEIREQEIANAIEQAQRIFDIEKASIQAQFDA 836 ++AEK A + KA E ++ Q + ++ ++ +A Q + Sbjct: 280 SAKIKTLEAEKAALEAEKA-DLEHQSQVLNANRQSLRRDLDASREAKKQLEAEHQKLEEQ 338 Query: 837 NKISNAQKVQMEKQLEDQLRAIKRNGLEERLKLEEQ 872 NKIS A + + + L D R K+ E KLEEQ Sbjct: 339 NKISEASRQSLRRDL-DASREAKKQLEAEHQKLEEQ 373
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 32.8 bits (74), Expect = 0.003 Identities = 22/114 (19%), Positives = 45/114 (39%), Gaps = 8/114 (7%) Query: 246 DELPAVQAVVDTLQTENAQLKQKVGDLEKNQMTPEKMEQAAAERATVIADAKALVPTVKT 305 + + ++Q ++TL A ++ + + Q E +A + A A + Sbjct: 195 EAISSLQIRMNTLTAAKASIEAAAANKAREQAAAEAKRKAEEQARQQAAIRAANTYAMPA 254 Query: 306 DGCSCEQIKRDVIAAKAGDALVGAVLGSVSVGDAKPEQIDTVFRALSAVKGKIA 359 +G V+A AG L+ G+ S+ A + I + R L++ +A Sbjct: 255 NG--------SVVATAAGRGLIQVAQGAASLAQAISDAIAVLGRVLASAPSVMA 300
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 25.9 bits (57), Expect = 0.035 Identities = 9/29 (31%), Positives = 15/29 (51%) Query: 16 EDVLPAFNLTVTEAANQLGVSRVTLSRVL 44 L A +AA+ LG++R TL + + Sbjct: 442 LAALTATRGNQIKAADLLGLNRNTLRKKI 470
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 33.3 bits (76), Expect = 0.001 Identities = 13/46 (28%), Positives = 20/46 (43%) Query: 104 LLADEINRCSPKTQSALLEAMEEGAVTVDGVRYVLPQPFWVIATQN 149 L DEI Q+ LL +++G T G R + ++A N Sbjct: 235 LFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVRIVAATN 280
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 28.4 bits (63), Expect = 0.014 Identities = 9/30 (30%), Positives = 17/30 (56%) Query: 8 VAKGLHRERQKAGLSLAELARRAGIAKSTL 37 VA L ++ + SL E+A+ AG+ + + Sbjct: 19 VALRLFSQQGVSSTSLGEIAKAAGVTRGAI 48
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 109 bits (274), Expect = 5e-35 Identities = 34/89 (38%), Positives = 52/89 (58%), Gaps = 1/89 (1%) Query: 7 NKSDLIERIALKNPHLAEPLVEEAVKIMIDQMIDALSNDNRIEIRGFGSFALHHRDPRVG 66 NK DLI ++A L + AV + + L+ ++++ GFG+F + R R G Sbjct: 3 NKQDLIAKVAEAT-ELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKG 61 Query: 67 RNPKTGKSVEVAAKAVPHFKPGKALRDAV 95 RNP+TG+ +++ A VP FK GKAL+DAV Sbjct: 62 RNPQTGEEIKIKASKVPAFKAGKALKDAV 90
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 85.3 bits (211), Expect = 1e-20 Identities = 31/141 (21%), Positives = 65/141 (46%), Gaps = 2/141 (1%) Query: 15 DQAAILIVDDVPENLGLLHESLDQAGYRVLVTTDGLSAIEIAHRCLPDMILLDGNMPHMD 74 A IL+ DD +L+++L +AGY V +T++ + D+++ D MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 75 GFESCLQLKASPITQLIPVIFMTGLSETEHIVKGFQVGGVDYVTKPLNIEEVLARVKTHL 134 F+ ++K +PV+ M+ + +K + G DY+ KP ++ E++ + L Sbjct: 62 AFDLLPRIKK--ARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 135 AHAKLLQQQKQVIDATEVAII 155 A K + + + ++ Sbjct: 120 AEPKRRPSKLEDDSQDGMPLV 140
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 57.5 bits (139), Expect = 2e-10 Identities = 27/113 (23%), Positives = 51/113 (45%), Gaps = 15/113 (13%) Query: 928 RILVVDNEAVDRGLVANFLRPLGFLLKEAESGIECLRQVPAFQPDLILMDLNMPMMGGWE 987 ILV D++A R ++ L G+ ++ + R + A DL++ D+ MP ++ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 988 TAHLLRQNNI--TNVPILIISANVNEREGNPQDAVLS-----EDFMLKPIDLN 1033 LL + ++P+L++SA A+ + D++ KP DL Sbjct: 65 ---LLPRIKKARPDLPVLVMSAQ-----NTFMTAIKASEKGAYDYLPKPFDLT 109
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 124 bits (312), Expect = 1e-36 Identities = 81/262 (30%), Positives = 121/262 (46%), Gaps = 10/262 (3%) Query: 2 SKQLDTKVAFITGSASGIGLEIAKKFAAEGAKVVISDVNAEKCEDAVKQLKQQGFDALAA 61 +K ++ K+AFITG+A GIG +A+ A++GA + D N EK E V LK + A A Sbjct: 3 AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62 Query: 62 PCDVTDEQAYQAAIELTQKHFGTVDILINNAGFQHVAAIEDFPTEVFQKLIAVMLTGAFI 121 P DV D A ++ G +DIL+N AG I E ++ +V TG F Sbjct: 63 PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122 Query: 122 GIKHVFPIMKAQKSGRIINMASINGLIGFAGKAGYNSAKHGVIGLTKVAALESAKDGITV 181 + V M ++SG I+ + S + A Y S+K + TK LE A+ I Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRC 182 Query: 182 NALCPGYVDTPLVR----GQIADLAKTRNVSETTALEDVILAMVPQKRLLTVEEIADYAI 237 N + PG +T + + + ET +P K+L +IAD + Sbjct: 183 NIVSPGSTETDMQWSLWADENGAEQVIKGSLETFKTG------IPLKKLAKPSDIADAVL 236 Query: 238 FLCSDKAGGVTGQAVVMDGGYT 259 FL S +AG +T + +DGG T Sbjct: 237 FLVSGQAGHITMHNLCVDGGAT 258
>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature. Length = 1541 Score = 65.1 bits (158), Expect = 3e-13 Identities = 52/328 (15%), Positives = 100/328 (30%), Gaps = 28/328 (8%) Query: 49 LVNPADIITPTE-QADTTSTQAAKTIQSTQTPVPDAPVIPMTPPEETQATTNAALAAATA 107 V+ +I TP QAD S + + P P P TP E T+ + + Sbjct: 991 TVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKT 1050 Query: 108 AAAKTAQIADAKREANLKAKAEAE-----------AESKAKAEEAAR------AKREAES 150 + + AK A+S ++ +E A E E Sbjct: 1051 VEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTETKETATVEKEE 1110 Query: 151 KAKADEAAK---AKHEADAKAKAEAAAKAKREAEAKAK-------AEATAKAKNEAETKA 200 KAK + K + K E + + +AE + E ++ A+T+ Sbjct: 1111 KAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQ 1170 Query: 201 KAEATAKAKHEAEAKAKAEAAAKAKREADAKAKADAAAKAKNEAEAKAKAEAAAKAKREA 260 A+ T+ + ++ + E N + ++ R Sbjct: 1171 PAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPKNRHRRSVRSV 1230 Query: 261 DAKAKAEATAKAKNEAEAKAKAEAAAKAKREADAKAKAEATAKAKNEAEAKAKADAAKAK 320 + T+ A + +DA+AKA+ A +A ++ + Sbjct: 1231 PHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQFVALNVGKAVSQHISQLEMNN 1290 Query: 321 AEQEAEAKASAAQKAEQEAAQKKAESRK 348 Q ++ + ++Q + S K Sbjct: 1291 EGQYNVWVSNTSMNKNYSSSQYRRFSSK 1318 Score = 64.7 bits (157), Expect = 4e-13 Identities = 53/310 (17%), Positives = 105/310 (33%), Gaps = 12/310 (3%) Query: 81 PDAPVIPMTPPEETQATTNAALAAATAAAAKTAQIADAKREANLKAKAEAEAESKAKAEE 140 P+ T T N A + + +IA EA + A A S+ Sbjct: 983 PEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIA-RVDEAPVPPPAPAT-PSETTETV 1040 Query: 141 AARAKREAESKAKADEAAKAKHEADAKAKAEAAAKAKREAEAKAKAEATAKAKNEAETKA 200 A +K+E+++ K ++ A E A+ + E A +AK +A + A++ +E + Sbjct: 1041 AENSKQESKTVEKNEQDAT---ETTAQNR-EVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096 Query: 201 KAEATAKAKHEAEAKAKAEAAAKAKREADAKAKADAAAKAKNEAEAKAKAEAAAKAKREA 260 E A E E KAK E + K + + K + + +AE A + Sbjct: 1097 TTETKETATVEKEEKAKVETEKTQE---VPKVTSQVSPKQEQSETVQPQAEPARE---ND 1150 Query: 261 DAKAKAEATAKAKNEAEAKAKAEAAAKAKREADAKAKAEATAKAKNEAEAKAKADAAKAK 320 E ++ A+ + A+ + + ++ T + E + Sbjct: 1151 PTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPT 1210 Query: 321 AEQEAEAKASAAQKAEQEAAQKKAESRKIASSAKKDFEQKIYRAWNIPMGSTGKKATARV 380 E+ K + + E +S+ + + N + +A A+ Sbjct: 1211 VNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRSTVALCDLTSTNTNAVLSDARAKAQF 1270 Query: 381 TLSDSGSVLS 390 + G +S Sbjct: 1271 VALNVGKAVS 1280 Score = 50.4 bits (120), Expect = 1e-08 Identities = 36/226 (15%), Positives = 73/226 (32%), Gaps = 6/226 (2%) Query: 212 AEAKAKAEAAAKAKREADAKAKADAAAKAKNEAEAKAKAEAAAKAKREADAKAKAEATAK 271 + + E A+ ++ A +K+E+ K E A Sbjct: 1000 PNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQESKTVEKNEQDAT 1059 Query: 272 AKNEAEAKAKAEAAAKAKREADAKAKAEATAKAKNEAEAKAKADAAKAKAEQEAEAKASA 331 E A+ + E A +AK A + A++ +E + + + K A E E KA Sbjct: 1060 ---ETTAQNR-EVAKEAKSNVKANTQTNEVAQSGSETK-ETQTTETKETATVEKEEKAKV 1114 Query: 332 AQKAEQEAAQKKAESRKIASSAKKDFEQKIYRAWNIPMGSTGKKATARVTLSDSGSVLSV 391 + QE + ++ ++ Q N P + + + T +D+ Sbjct: 1115 ETEKTQEVPKVTSQVSPKQEQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKE 1174 Query: 392 VVNSSDPDV-KASVEAAVRSAAPYPMPSDADARREARTFTSSFTAK 436 ++ + V +++ S P + + SS K Sbjct: 1175 TSSNVEQPVTESTTVNTGNSVVENPENTTPATTQPTVNSESSNKPK 1220
>adhesinb#Adhesin B signature. Length = 310 Score = 29.0 bits (65), Expect = 0.014 Identities = 21/97 (21%), Positives = 37/97 (38%), Gaps = 9/97 (9%) Query: 59 FLSREYDLSPILLAGIAFNEYRGMPSIMDTIAWTVRSAN--KVFANLTGYESSIKTLAKD 116 + S+ Y++ + I E G P + T+ +R +F + + +KT++KD Sbjct: 211 YFSKAYNVPSAYIWEI-NTEEEGTPDQIKTLVEKLRKTKVPSLFVESSVDDRPMKTVSKD 269 Query: 117 PGKTSIGDTSVQLRHFTDSSIKSQAEALYQINRTGYN 153 I FTDS + E + YN Sbjct: 270 TNIP-IYAKI-----FTDSVAEKGEEGDSYYSMMKYN 300
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 29.0 bits (65), Expect = 0.001 Identities = 8/34 (23%), Positives = 18/34 (52%), Gaps = 1/34 (2%) Query: 21 ALISIVPSNE-LWVSVKFKESPLKYLCIGQPVEL 53 L+ IVP ++ L V+ + + ++ +GQ + Sbjct: 355 TLMVIVPEDDTLEVTALVQNKDIGFINVGQNAII 388
>INTIMIN#Intimin signature. Length = 939 Score = 41.2 bits (96), Expect = 4e-05 Identities = 68/342 (19%), Positives = 112/342 (32%), Gaps = 28/342 (8%) Query: 760 HSITTTATDPAGNTSAASDALNFTVDSSNVVVSINKAIDDAGSKTGDLANNAATDDTTPT 819 + +T A D GN+S + L TV S+ VV D KT A+ T T Sbjct: 525 YKVTARAYDRNGNSSN-NVLLTITVLSNGQVVDQVGVTDFTADKTSAKADGTEAITYTAT 583 Query: 820 LVGTGTVGA---VVSISVDGGAVVGSAVVDSNGNWSYTLPSQSEGTHSYTATASNAAGTQ 876 + G A V V G AV+ + ++NG+ T+ +S+ +A A T Sbjct: 584 VKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQVVVSAKTAEMTS 643 Query: 877 G-TASFTLTIDTTAPDVPSIGQVNDDVGLIQGPLTQGASTDDTTPTLTGTGATPGDVIKV 935 A+ + +D T + I + G T + + Sbjct: 644 ALNANAVIFVDQTKASITEIKADKTTA------VANGQDAITYTVKVMKGDKPVSNQEVT 697 Query: 936 YDGN-DLVGSVTVGADGNWNYTIPAPGLTEGSHDLSVTATDPVGNESGKSDPFTLTVDLT 994 + + + T D N + T G +S +D T Sbjct: 698 FTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSD-----VAVDVKAPEVEFFT 752 Query: 995 APTAPSGTFNGGGSEITGSAEAGSVVKVKDANGNVLGSATADSSGKYTVTLADP---LND 1051 T + G EI G+ G + V G V A+ +GKYT A+P D Sbjct: 753 TL-----TIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASG-GNGKYTWRSANPAIASVD 806 Query: 1052 AETVKITATDKAGNESQAT--DLTAPNVIIDAEDNIVEAKVD 1091 A + ++T +K D I ++++ + Sbjct: 807 ASSGQVTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMS 848 Score = 33.9 bits (77), Expect = 0.007 Identities = 56/357 (15%), Positives = 99/357 (27%), Gaps = 27/357 (7%) Query: 440 ADGSYSIETRVVDAAGNTGTASTQVIVVDTQSPSATAVTADDLYDDVGAIQGTISNSPDS 499 Y + R D GN+ I V + V + D ++ ++ Sbjct: 521 GSNVYKVTARAYDRNGNSSNNVLLTITV---LSNGQVVDQVGVTDFTADKTSAKADGTEA 577 Query: 500 LTDDTRPTYSGTADASV-ATVKVYDNGAYLGSATVGTDGKWSFTPATPIGAGSHSFTASG 558 +T +G A A+V + + A L + + T+G T Sbjct: 578 ITYTATVKKNGVAQANVPVSFNIVSGTAVLSANSANTNGSGKATVTLKSDKPGQV----- 632 Query: 559 VDAAGNEGPQTTAWAFKVVGAAPSAPSIQSVLDDQGSVTGELQKNQTTDDRTPTISGTGQ 618 V +A + A V+ + SI + D+ + Q T + Sbjct: 633 VVSAKTAEMTSALNANAVIFVDQTKASITEIKADKTTAVANGQDAITYTVKV-MKGDKPV 691 Query: 619 VGAVVTVYVDGTAVGSSTVAADGTWSVKTTDLGADGVKNLVAKQTDGAGQS--------- 669 VT + +ST D K T K+LV+ + Sbjct: 692 SNQEVTFTTTLGKLSNSTEKTDTNGYAKVTLTSTTPGKSLVSARVSDVAVDVKAPEVEFF 751 Query: 670 ---SPDSGAYPIVLDTTAPATPGVVTAIDDQGVVQGPIANNGTTDDKNPEFKGTGSAGDV 726 + D G IV P V + T NP ++ Sbjct: 752 TTLTIDDGNIEIVGTGVKGKLPTVWLQYGQVNLKASGGNGKYTWRSANPAIASVDASSGQ 811 Query: 727 ITIKDGESVLGSTTVGADGTWSFTPSTG-----LDEGKHSITTTATDPAGNTSAASD 778 +T+K+ + S + T ++T +T + K A + N Sbjct: 812 VTLKEKGTTTISVISSDNQTATYTIATPNSLIVPNMSKRVTYNDAVNTCKNFGGKLP 868
>SECA#SecA protein signature. Length = 901 Score = 29.1 bits (65), Expect = 0.007 Identities = 13/52 (25%), Positives = 22/52 (42%) Query: 5 TMSELARQTGLKSSAIRYYEKEKLIHPIGRKGLQRVFSIQIIDQLALIHLAK 56 E R+ L S Y KE+++ + ++ +Q +D L HLA Sbjct: 730 LHEETLRERILAQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAA 781
>FLGMRINGFLIF#Flagellar M-ring protein signature. Length = 559 Score = 28.8 bits (64), Expect = 0.009 Identities = 8/53 (15%), Positives = 20/53 (37%), Gaps = 2/53 (3%) Query: 47 PMMGITTQVIMWIILSVLCTLLWFKFIKPLSIDKTKA--GLSREATIGQIGMV 97 + W+++ V+ +LW K ++P + + +A + Q Sbjct: 453 SFIDQLLAAGRWLLVLVVAWILWRKAVRPQLTRRVEEAKAAQEQAQVRQETEE 505
>cloacin#Cloacin signature. Length = 551 Score = 28.1 bits (62), Expect = 0.005 Identities = 11/31 (35%), Positives = 17/31 (54%), Gaps = 2/31 (6%) Query: 17 QTREYQDDEISRIIEMAWEDRTPFEAIEREF 47 Q ++ QD+E R + W+ P EA ER + Sbjct: 295 QVKQRQDEENRR--QQEWDATHPVEAAERNY 323
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 101 bits (252), Expect = 7e-27 Identities = 38/115 (33%), Positives = 62/115 (53%), Gaps = 1/115 (0%) Query: 7 TQASILIIDDEPQIRKFLDIALRAQGYAVHVAETGMKGLEILASQGADLLILDLGLPDMD 66 T A+IL+ DD+ IR L+ AL GY V + +A+ DL++ D+ +PD + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 67 GAEVLKEMRQ-WSQIPVIVLSARPDEQQKIKLLDAGANDYVTKPFSIQELCARIR 120 ++L +++ +PV+V+SA+ IK + GA DY+ KPF + EL I Sbjct: 62 AFDLLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIG 116
>PF05211#Neuraminyllactose-binding hemagglutinin Length = 260 Score = 30.8 bits (69), Expect = 0.014 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 13/96 (13%) Query: 112 PELISANLLKKEDLVLIKAGEII-----PADGEIVRGFATINESAVTGESAPVLREANTD 166 P L+ + L K + VLI AG + P GE + F + + L+ ++ Sbjct: 143 PGLLFSTGLDKMEGVLIPAGFVKVTILEPMSGESLDSFTM--DLSELDIQEKFLKTTHSS 200 Query: 167 RSGVIAGTKV-LTDQIVVRVSNEAGHSFLDKMIALV 201 SG + T V TD SN+A S L+K+ A + Sbjct: 201 HSGGLVSTMVKGTDN-----SNDAIKSALNKIFANI 231
>DNABINDINGHU#Prokaryotic integration host factor signature. Length = 91 Score = 111 bits (280), Expect = 5e-36 Identities = 37/88 (42%), Positives = 55/88 (62%) Query: 5 TKADMADHLSELTSLNRREAKQMVELFFDEISQALIAGEHVKLSGFGNFELRDKRERPGR 64 K D+ ++E T L ++++ V+ F +S L GE V+L GFGNFE+R++ R GR Sbjct: 3 NKQDLIAKVAEATELTKKDSAAAVDAVFSAVSSYLAKGEKVQLIGFGNFEVRERAARKGR 62 Query: 65 NPKTGEEIPISARRVVTFRAGQKFRQRV 92 NP+TGEEI I A +V F+AG+ + V Sbjct: 63 NPQTGEEIKIKASKVPAFKAGKALKDAV 90
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 55.3 bits (133), Expect = 1e-12 Identities = 21/65 (32%), Positives = 38/65 (58%) Query: 1 MRVRHGFTLIELMIVVAIIGILAAIAYPSYQNYKIRVNRSDVQSELIRVSQQLQSYKMVN 60 + GFTL+E+M+V+ IIG+LA++ P+ K + ++ S+++ + L YK+ N Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDN 63 Query: 61 HGYAN 65 H Y Sbjct: 64 HHYPT 68
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 52.6 bits (126), Expect = 2e-11 Identities = 19/60 (31%), Positives = 36/60 (60%) Query: 5 RQGFTLIELMVVVVIIAIFAAIAIPSYQEYIRRSNLAMAQQEMQKLAEQLERYRSRNFSY 64 ++GFTL+E+MVV+VII + A++ +P+ +++ A ++ L L+ Y+ N Y Sbjct: 7 QRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYKLDNHHY 66
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 28.0 bits (62), Expect = 0.019 Identities = 13/56 (23%), Positives = 26/56 (46%), Gaps = 3/56 (5%) Query: 4 QQQGATLIIVLMILLLIMVVGTLAIRQSISSLKMVSNNQI---QALLLQNSDAALM 56 +Q+G TL+ +++ILLL+ V + + +S + + +A L L Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQ 57
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 34.5 bits (79), Expect = 2e-04 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 2/64 (3%) Query: 2 KISRHSGFTLVELMVAIT-LGLLVTAAAIQLYITGITSYNVQKAMSSIQDSASFGVNYIL 60 + GFTL+E+MV I +G+L + L + + QKA+S I + Y L Sbjct: 3 ATDKQRGFTLLEIMVVIVIIGVLASLVVPNL-MGNKEKADKQKAVSDIVALENALDMYKL 61 Query: 61 DDVR 64 D+ Sbjct: 62 DNHH 65
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 27.9 bits (62), Expect = 0.014 Identities = 6/24 (25%), Positives = 15/24 (62%) Query: 3 MSKMRAQRGVGMVEVLVALLLLAI 26 M QRG ++E++V ++++ + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGV 24
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 39.1 bits (91), Expect = 1e-06 Identities = 17/66 (25%), Positives = 33/66 (50%), Gaps = 14/66 (21%) Query: 1 MTKMN---GFTLIELLVTIAVIAILATIAVPSFNSILNNQKLNASTRELMSKIAEARTQA 57 M + GFTL+E++V I +I +LA++ VP +++ N++ + +A + Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVP---NLMGNKE--------KADKQKAVSDI 49 Query: 58 VTLRQT 63 V L Sbjct: 50 VALENA 55
>PF00577#Outer membrane usher protein FimD Length = 878 Score = 284 bits (728), Expect = 1e-85 Identities = 132/815 (16%), Positives = 269/815 (33%), Gaps = 94/815 (11%) Query: 38 YLEVTLNNAPVP--DI-FQFTQEGNSLFT--SLEILQKLGINTSGLFTPQT--DIQHIDL 90 +++ LNN + D+ F + + L +G+NT+ + D + L Sbjct: 79 RVDIYLNNGYMATRDVTFNTGDSEQGIVPCLTRAQLASMGLNTASVSGMNLLADDACVPL 138 Query: 91 KT-VAGLTYEYDEAAQKLNLHVSLNLLNRKNEYAYDNKKEIAKLNPDQQKFGMLMNYDVY 149 + + T + D Q+LNL + ++ + + D L+NY+ Sbjct: 139 TSMIHDATAQLDVGQQRLNLTIPQAFMSNRARGYIPPE------LWDPGINAGLLNYNFS 192 Query: 150 AQSIENQH---ELNLWNEMRLFGVQGGLLSISSSSTFSKSSENNQFRSYI----LDTYWQ 202 S++N+ + ++ G+ G + ++T+S +S ++ S ++T+ + Sbjct: 193 GNSVQNRIGGNSHYAYLNLQS-GLNIGAWRLRDNTTWSYNSSDSSSGSKNKWQHINTWLE 251 Query: 203 KDYPDQLMSLVIGDAQSAAFSWARSTRISGISLSKNYNLQPYRVVTPLLKFKGESILPST 262 +D L +GD + + G L+ + N+ P G + + Sbjct: 252 RDIIPLRSRLTLGDGYTQGDIF-DGINFRGAQLASDDNMLPDSQRGFAPVIHGIARGTAQ 310 Query: 263 VDLFIDGLKQNTQSISPGQFEIQSKPTLNGAGNAQLVITDINGEQKTLSFKLYGTKSLLQ 322 V + +G ++ PG F I +G+ Q+ I + +G + + L + Sbjct: 311 VTIKQNGYDIYNSTVPPGPFTINDIYAAGNSGDLQVTIKEADGSTQIFTVPYSSVPLLQR 370 Query: 323 KGLDEWSFNLGVTKLDYATASFHYDDQPLFNGNYRYGLNAHTTVELHSELSPQLGLLGAG 382 +G +S G + A + F +GL A T+ ++L+ + G Sbjct: 371 EGHTRYSITAGEYRSGNA----QQEKPRFFQSTLLHGLPAGWTIYGGTQLADRYRAFNFG 426 Query: 383 VVQQLGTRGGVVNAAYAYSQHQEDQGGLYQ---------------------LGYSWSSRN 421 + + +G G ++ + + +GY +S+ Sbjct: 427 IGKNMG-ALGALSVDMTQANSTLPDDSQHDGQSVRFLYNKSLNESGTNIQLVGYRYSTSG 485 Query: 422 F-NFSYNTFKQQGTYTDIAGLMGYAFPEKMDQVYLGFYT--------------RFGQFGG 466 + NF+ T+ + Y K Y Y R Sbjct: 486 YFNFADTTYSRMNGYNIETQDGVIQVKPKFTDYYNLAYNKRGKLQLTVTQQLGRTSTLYL 545 Query: 467 SYIAQRYALDHTSSRYASFTWSQTFQSHA-NLSLSYNYNIEQRQNE--IYLGFSFPW--- 520 S Q Y + F+ LS S N Q+ + + L + P+ Sbjct: 546 SGSHQTYWGTSNVDEQFQAGLNTAFEDINWTLSYSLTKNAWQKGRDQMLALNVNIPFSHW 605 Query: 521 ------AQRKSVTVSTQNT---AGRQQSSATFMQSINQDRG-GWGGQLRVNQYDDGQSYL 570 +Q + + S + GR + A ++ +D + Q DG S Sbjct: 606 LRSDSKSQWRHASASYSMSHDLNGRMTNLAGVYGTLLEDNNLSYSVQTGYAGGGDGNSGS 665 Query: 571 GRLGYLGNSSEMA-IELQQSQFSGQQQTAISASLDGSLLWMGGQFAPMRRSLGAFALVST 629 L + S +Q + + G +L + LV Sbjct: 666 TGYATLNYRGGYGNANIGYSHSDDIKQ--LYYGVSGGVLAHANGVTLGQPLNDTVVLVKA 723 Query: 630 SGIPHVPVMLENRNVGYTNDQGFLLVNSLNAYQHNKLSIDTLKLPLDLQIKETQLDGVPR 689 G V EN+ T+ +G+ ++ Y+ N++++DT L ++ + + VP Sbjct: 724 PGAKDAKV--ENQTGVRTDWRGYAVLPYATEYRENRVALDTNTLADNVDLDNAVANVVPT 781 Query: 690 QSSGILVNFPIYKMISIQMQVIDINGNIVEMGSPVFRSSDQQEIETVVGREGIVYFEN-P 748 + + + F I + M + N + G+ V S+ + +V G VY P Sbjct: 782 RGAIVRAEFKARVGIKLLMTLTH-NNKPLPFGAMVT--SESSQSSGIVADNGQVYLSGMP 838 Query: 749 AQRHFFIQ---NNHQHCQIT--LPELKDKSGFVDL 778 ++ + HC LP + L Sbjct: 839 LAGKVQVKWGEEENAHCVANYQLPPESQQQLLTQL 873
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 735 bits (1898), Expect = 0.0 Identities = 221/1050 (21%), Positives = 431/1050 (41%), Gaps = 54/1050 (5%) Query: 28 LIQFAIQNAIWVLLFMVAWIGIGIYSYKNLAIDAVPDITNVQVQINSQANGFTATEVEQR 87 + F I+ I+ + + + G + L + P I V +++ G A V+ Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 88 ITYPIENAMAGLPSMEQTRSIS-RYGLSQVTIIFKDGTDIYWARQLINQRLQEAKSALPA 146 +T IE M G+ ++ S S G +T+ F+ GTD A+ + +LQ A LP Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120 Query: 147 SVDPQMSPISTGLGE-IYQWVIKAEPQAKKPDGSSYTAMDLREIQDWIVRPQLQRVPGVA 205 V Q + + + D T D+ + V+ L R+ GV Sbjct: 121 EVQQQGISVEKSSSSYLMVAGFVS-------DNPGTTQDDISDYVASNVKDTLSRLNGVG 173 Query: 206 EINSIGGYNKTYIVSPDLNRLQQLNLSLTTLQQALTDNNENRGAGFI------EDNGQQL 259 ++ G + D + L + L+ + L N+ AG + Sbjct: 174 DVQLFGA-QYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNA 232 Query: 260 TVRVPGMLSSIQDIENVTL-ETKSGLPIRVSDVAKVSIGHDLRTGGATYNGEETVLGIAM 318 ++ + ++ VTL G +R+ DVA+V +G + A NG+ Sbjct: 233 SIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIK 292 Query: 319 MMMGENSKTVAQALDAKVAQIQTSLPAGVVLETVYNRSTLVDRAIQTVAKNLIEGAILVI 378 + G N+ A+A+ AK+A++Q P G+ + Y+ + V +I V K L E +LV Sbjct: 293 LATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVF 352 Query: 379 VVLFIFLGNFRAALITACVIPLSMLFTLTGMAQQHISANLMSLG--ALDFGIIVDGAVVI 436 +V+++FL N RA LI +P+ +L T +A S N +++ L G++VD A+V+ Sbjct: 353 LVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVV 412 Query: 437 VENCIRRLAEAQQLQGRLLTRQERFKEVFLAAKQARRPLLFGQFIIMVVYLPIFALSGVE 496 VEN R + E + L +E ++ + Q + L+ ++ V++P+ G Sbjct: 413 VENVERVMMEDK------LPPKEATEK---SMSQIQGALVGIAMVLSAVFIPMAFFGGST 463 Query: 497 AKMFHPMAIAVVLALLGAMILSITFVPAAVALWV---TGEVKETESRWMLALKRA----- 548 ++ +I +V A+ ++++++ PA A + + E E + + Sbjct: 464 GAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSV 523 Query: 549 --YAALLDWAYAWRRVVLTSVVGILLITATISTRVGSEFAPQLSEGDFALQLMRAPSTGI 606 Y + L I+ + R+ S F P+ +G F + Sbjct: 524 NHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQ 583 Query: 607 EESLKIQAQVEQQLLK-QFPEIKAIFARTGTAEVATDVMPPNISDAVILLKPRKEWPDST 665 E + K+ QV LK + ++++F G + N A + LKP +E Sbjct: 584 ERTQKVLDQVTDYYLKNEKANVESVFTVNG---FSFSGQAQNAGMAFVSLKPWEERNGDE 640 Query: 666 ETIDELRARMLDAVAQLP-GNNSEFSQPIELRFNELISGVRSDIG-VKVFGDDLEVLNRE 723 + + + R + ++ G F+ P EL + D + G + L + Sbjct: 641 NSAEAVIHRAKMELGKIRDGFVIPFNMP---AIVELGTATGFDFELIDQAGLGHDALTQA 697 Query: 724 AEKIAQQL-KTISGASEVKVEQTDGLPLLNVKIDHALAAQYGLSIKAIQDLVATSIGGAS 782 ++ + + V+ + +++D A G+S+ I ++T++GG Sbjct: 698 RNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTY 757 Query: 783 VGQILQGDRRFDFVIRLDDQLR-TPQQLAMLPLQLPNGGLIQLQDVAIVETILGFSQVSR 841 V + R ++ D + R P+ + L ++ NG ++ + G ++ R Sbjct: 758 VNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLER 817 Query: 842 ENGKRRVIVTANVR-DRDLGSFVAEMQQSLAQQKLPSGYWLGYGGQFENLASAAARMQIV 900 NG + + G +A M+ KLP+G + G + + + Sbjct: 818 YNGLPSMEIQGEAAPGTSSGDAMALMEN--LASKLPAGIGYDWTGMSYQERLSGNQAPAL 875 Query: 901 IPLALLMIFILLVAVFHDLRESLLVFSGVPFALSGGIVALWFRDIPLSMSAGVGFIALSG 960 + ++ +++F+ L A++ + V VP + G ++A + + VG + G Sbjct: 876 VAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIG 935 Query: 961 VAVLNGLVMLTFIKELRLQ--YDIYTATWRGAVMRLRPVLMTACVASFGFIPMALATGTG 1018 ++ N ++++ F K+L + + AT MRLRP+LMT+ G +P+A++ G G Sbjct: 936 LSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAG 995 Query: 1019 AEVQRPLATVVIGGIISSTLLTLILLPVIY 1048 + Q + V+GG++S+TLL + +PV + Sbjct: 996 SGAQNAVGIGVMGGMVSATLLAIFFVPVFF 1025 Score = 84.1 bits (208), Expect = 2e-18 Identities = 48/317 (15%), Positives = 115/317 (36%), Gaps = 20/317 (6%) Query: 217 YIVSPDLNRLQQLNLSLTTLQQALTDNNENRGAGFIEDNGQQLTVRVPG---MLSSIQDI 273 + + D + Q L +SL+ + Q ++ D G+ + V +D+ Sbjct: 726 FKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDV 785 Query: 274 ENVTLETKSGLPIRVSDVAKVSIGHDLRTGGATYNGEETVLGIAMMMMGENSKTVAQALD 333 + + + + +G + S G + + + + A+ Sbjct: 786 DKLYVRSANGEMVPFSAFTTSHWV----YGSPRLERYNGLPSMEIQGEAAPGTSSGDAM- 840 Query: 334 AKVAQIQTSLPAGVVLETVYNRSTLVDRAIQTVAKNLIEGAILVIVVLFIFLGNFRAALI 393 A + + + LPAG+ + S + + ++V + L ++ + Sbjct: 841 ALMENLASKLPAGIGYD-WTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVS 899 Query: 394 TACVIPLSMLFTLTGMAQQHISANLMSLGAL--DFGIIVDGAVVIVENCIRRLAEAQQLQ 451 V+PL ++ L + ++ + L G+ A++IVE + + + Sbjct: 900 VMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVE----FAKDLMEKE 955 Query: 452 GRLLTRQERFKEVFLAAKQARRPLLFGQFIIMVVYLPIFALSGVEAKMFHPMAIAVVLAL 511 G+ + +A + RP+L ++ LP+ +G + + + I V+ + Sbjct: 956 GK-----GVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGM 1010 Query: 512 LGAMILSITFVPAAVAL 528 + A +L+I FVP + Sbjct: 1011 VSATLLAIFFVPVFFVV 1027 Score = 75.3 bits (185), Expect = 1e-15 Identities = 64/344 (18%), Positives = 143/344 (41%), Gaps = 22/344 (6%) Query: 724 AEKIAQQLKTISGASEVKVEQTDGLPLLNVKIDHALAAQYGLS----IKAIQDLVATSIG 779 A + L ++G +V++ + + +D L +Y L+ I ++ Sbjct: 159 ASNVKDTLSRLNGVGDVQL--FGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAA 216 Query: 780 GASVGQILQGDRRFDFVIRLDDQLRTPQQLAMLPLQL-PNGGLIQLQDVAIVETILG--- 835 G G ++ + I + + P++ + L++ +G +++L+DVA VE LG Sbjct: 217 GQLGGTPALPGQQLNASIIAQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVE--LGGEN 274 Query: 836 FSQVSRENGKRRVIVTANVRD----RDLGSFVAEMQQSLAQQKLPSGYWLGYG-GQFENL 890 ++ ++R NGK + + D + L Q P G + Y + Sbjct: 275 YNVIARINGKPAAGLGIKLATGANALDTAKAIKAKLAEL-QPFFPQGMKVLYPYDTTPFV 333 Query: 891 ASAAARMQIVIPLALLMIFILLVAVFHDLRESLLVFSGVPFALSGGIVALWFRDIPLS-M 949 + + + A++++F+++ ++R +L+ VP L G L ++ + Sbjct: 334 QLSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTL 393 Query: 950 SAGVGFIALSGVAVLNGLVMLTFIKELRL--QYDIYTATWRGAVMRLRPVLMTACVASFG 1007 + +A+ G+ V + +V++ ++ + + + AT + ++ A V S Sbjct: 394 TMFGMVLAI-GLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAV 452 Query: 1008 FIPMALATGTGAEVQRPLATVVIGGIISSTLLTLILLPVIYRWM 1051 FIPMA G+ + R + ++ + S L+ LIL P + + Sbjct: 453 FIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATL 496
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 34.0 bits (78), Expect = 0.001 Identities = 30/162 (18%), Positives = 59/162 (36%), Gaps = 27/162 (16%) Query: 149 ELIDQQANLSLAREALNLAAQDYQREKQLMNQGVSARQDYQRAYNAYRQAQIQVQAATQR 208 +L ++ + A+E L Q ++ E + RQ + T Sbjct: 274 QLEQIESEILSAKEEYQLVTQLFKNE----------------ILDKLRQTTDNIGLLTLE 317 Query: 209 LLAYGASAGSQGRYA-VRAPLSGTISSKDI-VVGEQVATGKPLFVI-DQLDQLWLEFILP 265 L A + + + +RAP+S + + G V T + L VI + D L + ++ Sbjct: 318 L----AKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQ 373 Query: 266 NSSTVAMQPGQ--KIKFVSL--QTQHEFEAQIQSLTAQADQD 303 N + GQ IK + +++++ A +D Sbjct: 374 NKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINLDAIED 415 Score = 33.3 bits (76), Expect = 0.002 Identities = 30/232 (12%), Positives = 64/232 (27%), Gaps = 27/232 (11%) Query: 94 LGEIQQQTRHPAKLVVNTDAQAHVGASFMAQVEQVNVSLGQSVKKGQVLATLFVP----E 149 LG+++ KL + ++ + + V+++ V G+SV+KG VL L + Sbjct: 77 LGQVEIVATANGKLTHSGRSKE-IKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEAD 135 Query: 150 LIDQQANLSLAR--EALNLAAQDYQREKQLMNQGVSARQDYQRAYNAYRQAQIQVQAATQ 207 + Q++L AR + +L + +Q + Sbjct: 136 TLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQF 195 Query: 208 RLLAYGASAGSQGRYAVRAPLSGTISSKDIVVGEQVATGKPLFVIDQLDQLWLEFILPNS 267 RA ++ +LD Sbjct: 196 STWQNQKYQKELNLDKKRAERLT------VLARINRYENLSRVEKSRLD----------- 238 Query: 268 STVAMQPGQKIKFVSLQTQHEFEAQIQSLTAQADQDTGRLQVRGKVLTAAKE 319 + ++ E E + + +L+ + +AKE Sbjct: 239 ---DFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKE 287
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 101 bits (252), Expect = 2e-27 Identities = 59/193 (30%), Positives = 103/193 (53%), Gaps = 2/193 (1%) Query: 19 ENVKGKVALITGASSGIGLTIAKRIAAAGAHVLLVARTQETLEEVKAAIEQQGGQASIFP 78 + ++GK+A ITGA+ GIG +A+ +A+ GAH+ V E LE+V ++++ + A FP Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 79 CDLTDMNAIDQLSQQIMASVDHVDFLINNAGRSIRRAVHESFDRFHDFERTMQLNYFGAV 138 D+ D AID+++ +I + +D L+N AG +H D ++E T +N G Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSD--EEWEATFSVNSTGVF 121 Query: 139 RLVLNLLPHMIKRKNGQIINISSIGVLANATRFSAYVASKAALDAFSRCLSAEVLKHKIS 198 ++ +M+ R++G I+ + S T +AY +SKAA F++CL E+ ++ I Sbjct: 122 NASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIR 181 Query: 199 ITSIYMPLVRTPM 211 + T M Sbjct: 182 CNIVSPGSTETDM 194
>TYPE3OMGPROT#Type III secretion system outer membrane G protein family signature. Length = 607 Score = 30.2 bits (68), Expect = 0.038 Identities = 26/129 (20%), Positives = 46/129 (35%), Gaps = 33/129 (25%) Query: 3 LNLILVESN-TMTDLVQQLASELAVRPNQVEAAIRLIDEGASVPFIARYRKEVTQGLDDT 61 LN I+V + + Q+L L ++E A+ ++D ++ Sbjct: 253 LNAIIVRDSPERMPMYQRLIHALDKPSARIEVALSIVD------------------INAD 294 Query: 62 QLRQLDTRLSYLRDLYERREKVIESLKEQ--------------NKLSDDLLARVNAAETK 107 QL +L + VI++ +Q + D LLARVN E + Sbjct: 295 QLTELGVDWRVGIRTGNNHQVVIKTTGDQSNIASNGALGSLVDARGLDYLLARVNLLENE 354 Query: 108 NSLEEIYAP 116 S + + P Sbjct: 355 GSAQVVSRP 363
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 100 bits (251), Expect = 2e-26 Identities = 40/136 (29%), Positives = 72/136 (52%), Gaps = 3/136 (2%) Query: 22 RILVVDDDVRLRTLLQRFLEDKGFVVKTAHDATQMDRLLQRELFSLIVLDFMLPVEDGLS 81 ILV DDD +RT+L + L G+ V+ +A + R + L+V D ++P E+ Sbjct: 5 TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64 Query: 82 ICRRLRQSNIDTPIIMLTARGSDSDRIAGLEAGADDYLPKPFNPNELLARIRAVL---RR 138 + R++++ D P+++++A+ + I E GA DYLPKPF+ EL+ I L +R Sbjct: 65 LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 139 QVREVPGAPSQQVEVV 154 + ++ + +V Sbjct: 125 RPSKLEDDSQDGMPLV 140
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.009 Identities = 14/87 (16%), Positives = 36/87 (41%), Gaps = 3/87 (3%) Query: 40 EQQDGLFLIATRDDKLVA--TLMGGYDGHRGWISYLAVHPQYQRQGIATALVQQLEKRLI 97 E++ + ++ + + ++G I +AV Y+++G+ TAL+ + + Sbjct: 61 EEEGKAAFLYYLENNCIGRIKIRSNWNG-YALIEDIAVAKDYRKKGVGTALLHKAIEWAK 119 Query: 98 ARGCPKVQLLIRKDNLDIQSFYDELGY 124 + L + N+ FY + + Sbjct: 120 ENHFCGLMLETQDINISACHFYAKHHF 146
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 49.4 bits (118), Expect = 1e-08 Identities = 25/84 (29%), Positives = 38/84 (45%), Gaps = 8/84 (9%) Query: 81 VQQTIQALGTVT-SSNTVVVHPLINGTLMQIYFKEGGLVHKGQLLALIDDRAPKAALLQA 139 V+ A G +T S + + P+ N + +I KEG V KG +L + +A L+ Sbjct: 80 VEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKT 139 Query: 140 QGQLLKDQALLTNAQLDLQRYAQL 163 Q LL A+L+ RY L Sbjct: 140 QSSLL-------QARLEQTRYQIL 156 Score = 32.1 bits (73), Expect = 0.005 Identities = 13/101 (12%), Positives = 39/101 (38%), Gaps = 10/101 (9%) Query: 116 GLVHKGQLLALIDDRAP-KAALLQAQGQLLKDQALLTNAQLDLQRYAQLWQQDSIAKQQY 174 + K +L + L + QL + ++ + +A+ + Q QL++ + + K Sbjct: 247 QAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDK--- 303 Query: 175 DTQASLVKQYQGVLKTDQAAVDNAKLQLSYTRVVSPVDGRI 215 ++Q + + + + + + +PV ++ Sbjct: 304 ------LRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKV 338
>PF06580#Sensor histidine kinase Length = 349 Score = 29.4 bits (66), Expect = 0.010 Identities = 19/88 (21%), Positives = 34/88 (38%), Gaps = 10/88 (11%) Query: 122 RARRQEFWSFQFF----YAVLGVSMLAFGHFLYLGHTLFIVSSIFMLLPALAVSVRRLHD 177 R + +W Q Y + G + L +F ++ I ++ L + R Sbjct: 6 RQANKYYWYCQGIGWGVYTLTGFGFASLYGSPKLHSMIFNIA-ISLMGLVLTHAYRSF-- 62 Query: 178 INRSGWLLLINLVPIVGVLI--VIFFFM 203 I R GWL L N+ I+ ++ + M Sbjct: 63 IKRQGWLKL-NMGQIILRVLPACVVIGM 89
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 77.2 bits (190), Expect = 2e-17 Identities = 77/387 (19%), Positives = 151/387 (39%), Gaps = 24/387 (6%) Query: 8 RSTFALSSIFALRMLGLFMIIPVFSIAGQSYQYAT--PALIGLAVGVYGLSQALLQIPFS 65 R + S AL +G+ +I+PV + ++ A G+ + +Y L Q Sbjct: 5 RPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLG 64 Query: 66 LVADRFSRKPLVVIGLLLFALGGAVAAMSHTIYGVIIGRAIAG-AGAVSAVVMALLADVT 124 ++DRF R+P++++ L A+ A+ A + ++ + IGR +AG GA AV A +AD+T Sbjct: 65 ALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYIADIT 124 Query: 125 REEQRTKAMAAMGMSIGLSFVVAFSVGPWLTSLVGISGLFWVTTVMGLVAILMLLLVPKV 184 ++R + M G V +G + + F + GL + L+P+ Sbjct: 125 DGDERARHFGFMSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPES 184 Query: 185 TRHHKNFQQGYLAQLKQVIQMGDLNR---LHLSVFSLHLLLTAMFIYVPSQLIE------ 235 + + + + ++VF + L+ + + E Sbjct: 185 HKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGEDRFHWD 244 Query: 236 --FAGIPLSKHGLVYLPLLLVSLFFAFPSIIVAEKYRKMRGIFLTAITGIIVGLLILIFG 293 GI L+ G+++ SL A + VA + + R + L + G ++L F Sbjct: 245 ATTIGISLAAFGILH------SLAQAMITGPVAARLGERRALML-GMIADGTGYILLAFA 297 Query: 294 YESKYILLTGLGIFFIAFNVMEALLPSWLSKSAPIQSKATAMGINASSQFLGAFFGGTLG 353 + + + + L + LS+ + + G A+ L + G L Sbjct: 298 TRGWMAFP--IMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLF 355 Query: 354 GQLLMLHNTSL-GWSILAAIAILWLLI 379 + T+ GW+ +A A+ L + Sbjct: 356 TAIYAASITTWNGWAWIAGAALYLLCL 382
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 38.7 bits (90), Expect = 7e-05 Identities = 36/169 (21%), Positives = 56/169 (33%), Gaps = 23/169 (13%) Query: 266 VVVESDKATVEVPSTVSGIVKAIHVKAGQDVKEGILLVTVEAEGAVASAPKAPV----AK 321 + ++ + IVK I VK G+ V++G +L+ + A GA A K A+ Sbjct: 90 LTHSGRSKEIKPIE--NSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQAR 147 Query: 322 AEAAPAPAAQK-------------AEAPAAKVETAPQAGADKLTKEQEA--ENSKVYAGP 366 E + E V L KEQ + +N K Sbjct: 148 LEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKEL 207 Query: 367 AVRKLARELGVVLAQVKASGEHGRLMKEDIYAYVKQRLTAPVAAPKAAA 415 + K E VLA++ R+ K + + L A K A Sbjct: 208 NLDKKRAERLTVLARINRYENLSRVEKSRLDDF--SSLLHKQAIAKHAV 254 Score = 32.5 bits (74), Expect = 0.006 Identities = 14/56 (25%), Positives = 29/56 (51%), Gaps = 1/56 (1%) Query: 41 SVEVPSTASGVVKSILVSLGDEVSEGTTLIELESGD-NTDKTESESAPAQTEVKAE 95 S E+ + +VK I+V G+ V +G L++L + D +++S+ Q ++ Sbjct: 96 SKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQT 151
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 47.8 bits (114), Expect = 4e-08 Identities = 49/218 (22%), Positives = 85/218 (38%), Gaps = 29/218 (13%) Query: 165 PISIMQNLDRAMKGASIGVEKMVVSC----LATAEASLLKDEKEYGVCLLDIGAGTTNIA 220 P+ Q RA++ ++ G V +A A + L + G ++DIG GTT +A Sbjct: 115 PVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGSMVVDIGGGTTEVA 174 Query: 221 VYLDGRLALARTLQRGGENVTRDIAAVLQTT------TEEAERIKILHGCVDLSAIKPDQ 274 V + + +++ GG+ I ++ AERIK G SA D+ Sbjct: 175 VISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHEIG----SAYPGDE 230 Query: 275 MIQV------QAIDGPQT--ISRIELAEIIIARYEEILGQVRDELER-----SGAIHGLY 321 + ++ A P+ ++ E+ E + I+ V LE+ + I Sbjct: 231 VREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALEQCPPELASDI--SE 288 Query: 322 HGVVLTGDACQIEGMISLARRILGVSAHLGNPPLQVYA 359 G+VLTG + + L G+ + PL A Sbjct: 289 RGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVA 326
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 46.9 bits (111), Expect = 5e-10 Identities = 16/69 (23%), Positives = 30/69 (43%) Query: 1 MDIKQKDDGKHGVFEGYDDEKLAGEMVYTWAGDQLFIIDHTDVADSYRGQGIGRQLLDAV 60 MD+ ++ F Y + G + + +I+ VA YR +G+G LL Sbjct: 55 MDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYALIEDIAVAKDYRKKGVGTALLHKA 114 Query: 61 IDFARKKQL 69 I++A++ Sbjct: 115 IEWAKENHF 123
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 59.1 bits (143), Expect = 1e-11 Identities = 79/390 (20%), Positives = 136/390 (34%), Gaps = 18/390 (4%) Query: 1 MKTNFPLLALAIGAFAIGTTEFSPMGLLPNIAHDLNISIPTA---GMLITGYALGVMLGA 57 MK N PL+ + M +LP + DL S G+L+ YAL A Sbjct: 1 MKPNRPLIVILSTVALDAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACA 60 Query: 58 PIMTLWFGHFSRRKALILLMTLFTVGNLLAAVAPNYWSLMAARLITSLNHGAFFGIGSVV 117 P++ F RR L++ + V + A AP W L R++ + G+ + Sbjct: 61 PVLGALSDRFGRRPVLLVSLAGAAVDYAIMATAPFLWVLYIGRIVAGITGATGAVAGAYI 120 Query: 118 AASVVPVHKQASAVASMFMGLTIANIGGVPLATWLGQVIGWRMTFFAISGLGLLTMWSLY 177 A + ++A M + G L +G FFA + L L + Sbjct: 121 -ADITDGDERARHFGFMSACFGFGMVAGPVLGGLMGG-FSPHAPFFAAAALNGLNFLTGC 178 Query: 178 QALPQGSAGQRTDVKAELKVLSRIPVLMALMTTVLGASAMFTLYTYIAPSLTA----FT- 232 LP+ G+R ++ E MT V A+F + + A F Sbjct: 179 FLLPESHKGERRPLRREALNPLASFRWARGMTVVAALMAVFFIMQLVGQVPAALWVIFGE 238 Query: 233 ---HASPMFITFMLVLIGIGFSIGN-HLGGKFADLSLNKTLIGFLSLLILIMLAFPWLAQ 288 H I L GI S+ + G A + + + +I + LA Sbjct: 239 DRFHWDATTIGISLAAFGILHSLAQAMITGPVAARLGERRAL--MLGMIADGTGYILLAF 296 Query: 289 SHLGAAIALVIWGIATFGLVPPVQMRVM--KIAHEAPGLASSINVGAFNLGNAVGAAVGG 346 + G ++ +A+ G+ P ++ ++ E G +L + VG + Sbjct: 297 ATRGWMAFPIMVLLASGGIGMPALQAMLSRQVDEERQGQLQGSLAALTSLTSIVGPLLFT 356 Query: 347 LVLSLNLGYAAVSFAGAGLAGFGLLLVLLQ 376 + + ++ AG A + L L L+ Sbjct: 357 AIYAASITTWNGWAWIAGAALYLLCLPALR 386
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 469 bits (1209), Expect = e-151 Identities = 224/1065 (21%), Positives = 445/1065 (41%), Gaps = 78/1065 (7%) Query: 5 LSEWALKNKGLILYLMLLLAIVGIFSYSKLSQSEDPPFTFKVMVIKTYWPGATAKEVSTL 64 ++ + ++ L ++L + G + +L ++ P + + +PGA A+ V Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 65 VTDRIEKELMTTGQYDHIMAYS-RPGESMVTFFAKDSLKSEQIPDVWYN-VRKKVNDIKQ 122 VT IE+ + ++ + S G +T + PD+ V+ K+ Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTD----PDIAQVQVQNKLQLATP 116 Query: 123 ELPVGVQGP-FFNDEFGDTFGNIYVLTGEGFDY--AVLKEYADR-LQLELQRVPDVAKVE 178 LP VQ ++ ++ + + + +Y ++ L R+ V V+ Sbjct: 117 LLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQ 176 Query: 179 LVGLQDQKIWIELSNTKMAQLGVPVTAIQQALQQQNNMVSAGFFE-TPSDRIQ-----VR 232 L G Q + I L + + + + L+ QN+ ++AG TP+ Q + Sbjct: 177 LFGAQYA-MRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASII 235 Query: 233 LTGHLNRVEDLKHLPLLVGD--KTIQLGEVAEIYRGFSDPAQPRMRFMGQNGIGIAVSMR 290 E+ + L V ++L +VA + G + R G+ G+ + + Sbjct: 236 AQTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNV-IARINGKPAAGLGIKLA 294 Query: 291 KGGDIIALGKHLETTFSDLQHTLPLGMKLEKVSDQPVAVQRSIHEFIKVLAEAVIIVLLV 350 G + + K ++ ++LQ P GMK+ D VQ SIHE +K L EA+++V LV Sbjct: 295 TGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLV 354 Query: 351 SFFSLG-FRTGLVVAFSIPLVLAMTFAGMHIFDVGLHKISLGALILALGLLVDDAIIAVE 409 + L R L+ ++P+VL TFA + F ++ +++ ++LA+GLLVDDAI+ VE Sbjct: 355 MYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVE 414 Query: 410 MMA-IKMEQGYSRLKAAGFAWKSTAFPMLTGTLITAAGFLPIATANSSTGEYTRSIFQVV 468 + + ME +A + ++ ++ +A F+P+A STG R + Sbjct: 415 NVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITI 474 Query: 469 TIALIVSWVAAVLFVPYLGEKLLPDFNQMQQRVP-----WYQRIWAKLRKQPVPQLASYQ 523 A+ +S + A++ P L LL + W+ + Sbjct: 475 VSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHS------------ 522 Query: 524 EHHDPYQTRFYQTFRNMVEACVRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEIL 583 Y N V + ++ L+ AG ++LF +P F P ++ L Sbjct: 523 -------VNHYT---NSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFL 572 Query: 584 VDIKLEEGASLTATEQAVKKVEHFLSQQKGIDNYVAYVGTGSPRFYLPLDQQLPQASFAQ 643 I+L GA+ T++ + +V + + + + + G + Q Q + Sbjct: 573 TMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNG----FSFSGQ--AQNAGMA 626 Query: 644 FVVL------ASSLEDRNEIRHSLDQQIK-----LLLPQARTRVSLLENGPPVGYPLQYR 692 FV L + H ++ ++P + L + L + Sbjct: 627 FVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQ 686 Query: 693 VSGEDQNLVREWAQKVAKVIAENPNA-TNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDL 751 +G + + + ++ + A++P + +V + E + L +DQ++A+ LGVS +D+ Sbjct: 687 -AGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDI 745 Query: 752 ANFLNSSITGTVIDQYREKRELIEIRLRGDQAERVDVASLASLAIPTSHGGTVPLAQIAR 811 +++++ GT ++ + ++ + ++ ++ D R+ + L + +++G VP + Sbjct: 746 NQTISTALGGTYVNDFIDRGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTT 805 Query: 812 IEYRFEDGIIWHRDRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNGYLIDVGGT 871 + + + + LP++ ++ + P T M+ L +LP G D G Sbjct: 806 SHWVYGSPRLERYNGLPSMEIQG----EAAPGTSSGDAMALMENLASKLPAGIGYDWTGM 861 Query: 872 VEESAKGQESVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKP 931 + A + + VV L S S V L PLG++GV L LF++ Sbjct: 862 SYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQK 921 Query: 932 FGFVAMLGTIALSGMIMRNALILIDQIEQDVAA-GHEVWTAIIDATVRRFRPILLTALAA 990 M+G + G+ +NA+++++ + + G V A + A R RPIL+T+LA Sbjct: 922 NDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAF 981 Query: 991 VLAMIPLSRSIFFG-----PMAVAIMGGLIVATFLTLFFLPALYA 1030 +L ++PL+ S G + + +MGG++ AT L +FF+P + Sbjct: 982 ILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFV 1026 Score = 89.1 bits (221), Expect = 5e-20 Identities = 74/525 (14%), Positives = 171/525 (32%), Gaps = 47/525 (8%) Query: 540 MVEACVRYRKTVIVTTVLLFAGSLLLFKFVPQQFFPPSNRAEILVDIKLEEGASLTATEQ 599 M +R V ++L L +P +P + V + T + Sbjct: 1 MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60 Query: 600 AVKKVEHFLSQQKGIDN---YVAYVGTGSPRFYLPLDQQLPQASFAQFVVLASSLEDRNE 656 + +E ++ + G+ + A + + Sbjct: 61 VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIA--------------QVQ 106 Query: 657 IRHSLDQQIKLLLPQARTRVSLLENGPPVGYPLQYRVSGEDQNL----VREWAQKVAK-V 711 +++ L Q LLPQ + + Y + ++ + ++ K Sbjct: 107 VQNKL-QLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDT 165 Query: 712 IAENPNATNVHLDWGEPSKLIMLNIDQDRARQLGVSNTDLANFLNS----SITGTVIDQY 767 ++ +V L + + + +D D + ++ D+ N L G + Sbjct: 166 LSRLNGVGDVQLFGAQ--YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTP 223 Query: 768 REKRELIEIRLRGDQAERVDVASLASLAIPTS-HGGTVPLAQIARIEYRFED--GIIWHR 824 + + + Q + + + + G V L +AR+E E+ I Sbjct: 224 ALPGQQLNASIIA-QTRFKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARIN 282 Query: 825 DRLPTITVRADMRSQLQPATVVDQMKLQMQELRRQLPNG----YLIDVGGTVEESAKGQE 880 + P + + + +K ++ EL+ P G Y D V+ S E Sbjct: 283 GK-PAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSI--HE 339 Query: 881 SVNAGMPLFLAVVMTLLMVKLRSLSRAFIVFLTAPLGLIGVTLFLLLFDKPFGFVAMLGT 940 V + V + + + L+++ I + P+ L+G L F + M G Sbjct: 340 VVKTLFEAIMLVFLVMYLF-LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGM 398 Query: 941 IALSGMIMRNALILIDQIEQDVAAGHE-VWTAIIDATVRRFRPILLTALAAVLAMIPL-- 997 + G+++ +A+++++ +E+ + A + + ++ A+ IP+ Sbjct: 399 VLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAF 458 Query: 998 ---SRSIFFGPMAVAIMGGLIVATFLTLFFLPALYAAWFKVKKTP 1039 S + ++ I+ + ++ + L PAL A K Sbjct: 459 FGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAE 503
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 42.1 bits (99), Expect = 2e-06 Identities = 22/204 (10%), Positives = 64/204 (31%), Gaps = 11/204 (5%) Query: 23 HKQTADLEQAPLVMVAQPQSSQSQAQSYAGKVQARQQTALSFRVGGQIIERLVEVGDRVH 82 +Q + + +++ + ++ + + + L+ Sbjct: 192 KEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQ---- 247 Query: 83 VGQVLAKLDVQDAQLQLNAAKAQLDNAQSAAKIAADELQRYQQLLPINAVSRSQYDAIKN 142 +AK V + + + A +L +S + E+ ++ + + + Sbjct: 248 ---AIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEY-QLVTQLFKNEILD- 302 Query: 143 QYDAAQSSLKQARSNYDVASNQTNYNRLLANKNGVITERLI-EVGQVVAAGQTAYQLAID 201 + ++ + + + A + + + + G VV +T + + Sbjct: 303 KLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPE 362 Query: 202 GDR-EVVIGLPEQSISSVKVGQPA 224 D EV + + I + VGQ A Sbjct: 363 DDTLEVTALVQNKDIGFINVGQNA 386 Score = 41.0 bits (96), Expect = 6e-06 Identities = 21/108 (19%), Positives = 37/108 (34%), Gaps = 14/108 (12%) Query: 66 VGGQIIERLVEVGDRVHVGQVLAKLDVQDAQLQLNAAKAQLDNAQ------SAAKIAADE 119 + E +V+ G+ V G VL KL A+ ++ L A+ + + Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162 Query: 120 LQRYQQLLPINAVSRS--------QYDAIKNQYDAAQSSLKQARSNYD 159 + + LP ++ IK Q+ Q+ Q N D Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLD 210
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 72.0 bits (176), Expect = 8e-18 Identities = 40/202 (19%), Positives = 79/202 (39%), Gaps = 10/202 (4%) Query: 1 MQASGRPKDLEKRKRILEAAKIAFLKHGYHNASMNQIAKDAGVTKLTVYNHFQDKANLFI 60 M + + E R+ IL+ A F + G + S+ +IAK AGVT+ +Y HF+DK++LF Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 CAIEESCQECI-ATRNFQLSAENDFLQSLHHVCECAIYTIYLPEALKLEHVL---FELAA 116 E S +Q D L L + + + E +L + Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHKCEFV 120 Query: 117 EQSPLTEKFFNASHQRLCGSMTDFFQQASNLGFIRADIPIKQT-ELIMSLLLGLRHHHVL 175 + + ++ + + + AD+ ++ ++ + GL + + Sbjct: 121 GEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180 Query: 176 LGMEAAPNTDELQQSITDAIEI 197 AP + +L++ D + I Sbjct: 181 -----APQSFDLKKEARDYVAI 197
>PF07201#Hypersensitivity response secretion protein HrpJ Length = 293 Score = 31.0 bits (70), Expect = 0.009 Identities = 7/45 (15%), Positives = 17/45 (37%) Query: 331 IHSILEAVWTKGRDLSFKSHFQAMQQQLGIAQLVSLDDAQQLLKQ 375 + + +K +L K + + L + +SL + L+ Sbjct: 83 VEEQVNQYLSKVPELEQKQNVSELLSLLSNSPNISLSQLKAYLEG 127
>CHANLCOLICIN#Channel forming colicin signature. Length = 522 Score = 28.5 bits (63), Expect = 0.016 Identities = 30/119 (25%), Positives = 54/119 (45%), Gaps = 7/119 (5%) Query: 38 EDLKAQIGKLEESLKLEKARTANAVYEAEKVKERAERE-ADTAKKFALEKFAKSLLDSVD 96 ED + ++ K EE + E A EAE+ ++ ERE A+T ++ L + + L ++ Sbjct: 126 EDERLRLAKAEEKARKEAEAAEKAFQEAEQRRKEIEREKAETERQLKLAEAEEKRLAALS 185 Query: 97 NLERAIQAAGKEKTPL------LEGVELTLKSLTTTLEKFDVVSVDTTNGFNAELHQAV 149 +A++ A K+ + ++G TL S ++ + T G EL QA Sbjct: 186 EEAKAVEIAQKKLSAAQSEVVKMDGEIKTLNSRLSSSIHARDAEMKTLAGKRNELAQAS 244
>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein signature. Length = 347 Score = 141 bits (358), Expect = 2e-39 Identities = 81/380 (21%), Positives = 142/380 (37%), Gaps = 69/380 (18%) Query: 5 IGIDLGTTNSCVAVLEGDKVKVIENAEGTRTTPSIVAYKDSEILVGQSAKRQAVTNPKNT 64 + IDLGT N+ + V V + R S VG AK+ P N Sbjct: 13 LSIDLGTANTLIYVKGQGIVLNEPSVVAIRQDR--AGSPKSVAAVGHDAKQMLGRTPGN- 69 Query: 65 LFAIKRLIGRRYEDQAVQKDIGLVPYKIIKADNGDAWVEVNDKKLAPQQVSAEILKK-MK 123 + AI+ P K D +A V+ ++L+ +K Sbjct: 70 IAAIR-------------------PMK--------------DGVIADFFVTEKMLQHFIK 96 Query: 124 KTAEDYLGETVTEAVITVPAYFNDAQRQATKDAGRIAGLDVKRIINEPTAAALAFGMDKK 183 + + ++ VP +R+A +++ + AG +I EP AAA+ G+ Sbjct: 97 QVHSNSFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVS 156 Query: 184 EGDRKVAVYDLGGGTFDVSIIEIADLDGDQQIEVLSTNGDTFLGGEDFDTALIDYLVEEF 243 E V D+GGGT +V++I + + + +GG+ FD A+I+Y+ + Sbjct: 157 E-ATGSMVVDIGGGTTEVAVISLNG---------VVYSSSVRIGGDRFDEAIINYVRRNY 206 Query: 244 KKEQSVNLKNDPLALQRLKEAAEKAKIELSSS----SSTEINLPYITADATGPKHLVINV 299 + AE+ K E+ S+ EI + P+ +N Sbjct: 207 GSLIG-------------EATAERIKHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLN- 252 Query: 300 TRAKLEGLVADLVARTIEPCRIALKD-AGLSTSDISD--VILVGGQSRMPMVQQKVQEFF 356 + LE L + + + +AL+ SDIS+ ++L GG + + + + + E Sbjct: 253 SNEILEALQ-EPLTGIVSAVMVALEQCPPELASDISERGMVLTGGGALLRNLDRLLMEET 311 Query: 357 GKEPRKDVNPDEAVAIGAAI 376 G +P VA G Sbjct: 312 GIPVVVAEDPLTCVARGGGK 331
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 133 bits (337), Expect = 1e-36 Identities = 99/424 (23%), Positives = 181/424 (42%), Gaps = 16/424 (3%) Query: 3 MNATPSHQRLQPEFRLLVLLVSIGFFMQALDTTIVNTALPAMARHLNEDPLHMHGVVVAY 62 MN + S L+ ++L+ L + FF L+ ++N +LP +A N+ P + V A+ Sbjct: 1 MNTSYSQSNLRHN-QILIWLCILSFF-SVLNEMVLNVSLPDIANDFNKPPASTNWVNTAF 58 Query: 63 VLSVAAFIPLSGWLADRFGVRNTYFAAIVIFTLASLGCGLSQSLNQ-LIFFRVIQGLGGA 121 +L+ + + G L+D+ G++ I+I S+ + S LI R IQG G A Sbjct: 59 MLTFSIGTAVYGKLSDQLGIKRLLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAA 118 Query: 122 LLLPVGRLAMLKLIPRTQFLSAMSLMSLAGLIGPLIGPTLGGWLVEVATWHWVFLINIPM 181 + + + + IP+ A L+ +G +GP +GG + HW +L+ IPM Sbjct: 119 AFPALVMVVVARYIPKENRGKAFGLIGSIVAMGEGVGPAIGGMIAH--YIHWSYLLLIPM 176 Query: 182 GLLGILVTFKAMPNVKQKEVKSFDLSGFVLLMVAMIGLSLGIEQLSSREYPQWVSISLLI 241 + + + + + FD+ G +L+ V ++ L SIS LI Sbjct: 177 ITIITVPFLMKLLKKEVRIKGHFDIKGIILMSVGIVFFMLFTTS---------YSISFLI 227 Query: 242 AGILATIIYAYHSHMHENALFRSTLFKNKIYAIGVLGNFFARFGGNAVPFILPLMLQVAF 301 +L+ +I+ H + L KN + IGVL ++P M++ Sbjct: 228 VSVLSFLIFVKHIRKVTDPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVH 287 Query: 302 GFEPFYTG-LMMIPLVLGSLFSKPIVRPIIQRLGYRNVLLTNTILVGCCIASFSLTTAET 360 G +++ P + + I ++ R G VL + + S T Sbjct: 288 QLSTAEIGSVIIFPGTMSVIIFGYIGGILVDRRGPLYVLNIGVTFLSVSFLTASFLLETT 347 Query: 361 PEWLRAIHFFIFGTLNSIQFVSMNTLTLKDLSQQQASSGNSFLSMIMMLSMSIGVALAGT 420 ++ I F+ G L+ + ++T+ L QQ+A +G S L+ LS G+A+ G Sbjct: 348 SWFMTIIIVFVLGGLSFTK-TVISTIVSSSLKQQEAGAGMSLLNFTSFLSEGTGIAIVGG 406 Query: 421 LVNM 424 L+++ Sbjct: 407 LLSI 410
>SECA#SecA protein signature. Length = 901 Score = 31.8 bits (72), Expect = 0.001 Identities = 9/13 (69%), Positives = 10/13 (76%) Query: 142 CICGSAKKFKQCC 154 C CGS KK+KQC Sbjct: 885 CPCGSGKKYKQCH 897
>TCRTETA#Tetracycline resistance protein signature. Length = 399 Score = 52.1 bits (125), Expect = 2e-09 Identities = 38/168 (22%), Positives = 72/168 (42%), Gaps = 7/168 (4%) Query: 30 DALDTGIIAFIMTTLVKDWALT---PAESGWIVSIGFIGMALGAVFSGGLADRFGRKTVF 86 DA+ G+I ++ L++D + A G ++++ + A G L+DRFGR+ V Sbjct: 17 DAVGIGLIMPVLPGLLRDLVHSNDVTAHYGILLALYALMQFACAPVLGALSDRFGRRPVL 76 Query: 87 ATTLLIYSLATAACAFAPNLTWLLAFRFIVGLGLGGQLPVAVTLVSEYIPAHVRGRFIVL 146 +L ++ A A AP L L R + G+ G VA +++ R R Sbjct: 77 LVSLAGAAVDYAIMATAPFLWVLYIGRIVAGIT-GATGAVAGAYIADITDGDERARHFGF 135 Query: 147 LESFWGLGWLVAALVSYF---VIPHFGWHIAFLIGGLPAIYVYVIIKK 191 + + +G G + ++ PH + A + GL + ++ + Sbjct: 136 MSACFGFGMVAGPVLGGLMGGFSPHAPFFAAAALNGLNFLTGCFLLPE 183
>PYOCINKILLER#Pyocin S killer protein signature. Length = 617 Score = 29.4 bits (65), Expect = 0.045 Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Query: 335 AMGGGMAVL---PSTAEAWKRITGVTIIEGYGL--SETSPVATVNPPASSEFSGTIGIPL 389 M G A L TAE W+ T ++ G+ ++ +VN A ++ SGT+ +P+ Sbjct: 298 VMAVGFASLTYSSRTAEQWQDQTPDSVRYALGMDAAKLGLPPSVNLNAVAKASGTVDLPM 357 Query: 390 PLTDVA 395 LT+ A Sbjct: 358 RLTNEA 363
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 28.3 bits (63), Expect = 0.036 Identities = 7/24 (29%), Positives = 11/24 (45%) Query: 113 VSPETLKSLVNWQWPSNSIQLNNI 136 E L+ + WP N +L N+ Sbjct: 338 FDQEALELMKAHPWPGNVRELENL 361
>BCTERIALGSPC#Bacterial general secretion pathway protein C signature. Length = 272 Score = 56.5 bits (136), Expect = 2e-11 Identities = 51/270 (18%), Positives = 96/270 (35%), Gaps = 38/270 (14%) Query: 27 VLILWLCWKLAALFWLLLAPPQV----MQFERVQLGSQQAQIPNISSFALFNEPNVTNNA 82 +L+L C +LA +FW + P +Q Q Q + + + F + E N Sbjct: 21 LLMLLFCQQLAMIFWRIGLPDNAPVSSVQITPAQARQQPVTLNDFTLFGVSPEKNKAGAL 80 Query: 83 NDQQ---------NFELQGVMLAYPARFSSAVIKGKENADRYRIGDAVDNSSYQLAEVYW 133 + Q N L GVM S A+I + + V + ++ + Sbjct: 81 DASQMSNLPPSTLNLSLTGVMAGDDDSRSIAIISKDNEQFSRGVNEEVPGYNAKIVSIRP 140 Query: 134 DHVVLRQSNGATREIRFKGMEKGLYQPIVPPASATTSTTNDEHPSSPPSASSAIGQAIQQ 193 D VVL+ + R++ + GLY + E S + + + +QQ Sbjct: 141 DRVVLQ------YQGRYEVL--GLY--------------SQEDSGSDGVPGAQVNEQLQQ 178 Query: 194 M-QQNRDQYLQNMGVSNSGE--GYEVTDRTPSALKNTLGLRAGDRILSVNGQRVGQGQND 250 Y+ + N + GY + S +GL+ D +++NG + + Sbjct: 179 RASTTMSDYVSFSPIMNDNKLQGYRLNPGPKSDSFYRVGLQDNDMAVALNGLDLRDAEQA 238 Query: 251 VQLLEQARRDGQVKIEIKRGDQVMTIQQSF 280 + +E+ + ++R Q I F Sbjct: 239 KKAMERMADVHNFTLTVERDGQRQDIYMEF 268
>BCTERIALGSPD#Bacterial general secretion pathway protein D signature. Length = 660 Score = 433 bits (1116), Expect = e-144 Identities = 236/688 (34%), Positives = 335/688 (48%), Gaps = 81/688 (11%) Query: 11 ALVAAAPMMAVISTSAYAQTWKINLRDADLTAFINEVADITGKNFAIDPRVRGNVTVISN 70 L+ A ++ A A+ + + + D+ FIN V+ K IDP VRG +TV S Sbjct: 13 TLLIFAALLFR---PAAAEEFSASFKGTDIQEFINTVSKNLNKTVIIDPSVRGTITVRSY 69 Query: 71 KPLNRDEVYDLFLGVLNVNGVVAIPSGN-TIKLVPDSNVKNAGVPYDMR-NRARGDQVVT 128 LN ++ Y FL VL+V G I N +K+V + K A VP GD+VVT Sbjct: 70 DMLNEEQYYQFFLSVLDVYGFAVINMNNGVLKVVRSKDAKTAAVPVASDAAPGIGDEVVT 129 Query: 129 RVIWVENTNPNDLIPALRPLMPQFANLAAV--AGTNALIVSDRASNIAQLETIIRNLDGT 186 RV+ + N DL P LR L + V +N L+++ RA+ I +L TI+ +D Sbjct: 130 RVVPLTNVAARDLAPLLRQLNDNAGVGSVVHYEPSNVLLMTGRAAVIKRLLTIVERVDNA 189 Query: 187 GQNDVEAIALQNSQAEEIIGLLESMSSTGASKDLNGSRV-RIIADTRTNRILIKGDPGTR 245 G V + L + A +++ L+ ++ + L GS V ++AD RTN +L+ G+P +R Sbjct: 190 GDRSVVTVPLSWASAADVVKLVTELNKDTSKSALPGSMVANVVADERTNAVLVSGEPNSR 249 Query: 246 KRIRHMIETLDVPSADRLGGLKVFRLKYASAKSLAEILQGLVTGQSSSSSNNASGNQNSR 305 +RI MI+ LD A G KV LKYA A L E+L G+ SS+ + + Sbjct: 250 QRIIAMIKQLDRQQA-TQGNTKVIYLKYAKASDLVEVLTGI----SSTMQSEKQAAKPVA 304 Query: 306 TGSNNSISSLIGNTASNNSTTGTNSGSVAGSSINLNSTNNNNQNSITSFNNNGVSIIADS 365 + + I A Sbjct: 305 AL------------------------------------------------DKNIIIKAHG 316 Query: 366 AQNALVVKADPQLMREIEAAIQQLDVRREQVLIEAAIIEVSGDDSDQLGIQWALGDLNSG 425 NAL+V A P +M ++E I QLD+RR QVL+EA I EV D LGIQWA N Sbjct: 317 QTNALIVTAAPDVMNDLERVIAQLDIRRPQVLVEAIIAEVQDADGLNLGIQWA----NKN 372 Query: 426 VGLLSFSNVGASLASIAAG---YASTGTAGAAAAIASGTNSGNGATFAVGDFSNSRKAYG 482 G+ F+N G +++ AG Y GT ++ A A + +G A F G++ Sbjct: 373 AGMTQFTNSGLPISTAIAGANQYNKDGTVSSSLASALSSFNGIAAGFYQGNW-------A 425 Query: 483 ALIQALKSNTKSNVLSTPSIVTMDNEEAYIVVGQNVPFVTGSVSTGSTGTINPYTTVERK 542 L+ AL S+TK+++L+TPSIVT+DN EA VGQ VP +TGS +T N + TVERK Sbjct: 426 MLLTALSSSTKNDILATPSIVTLDNMEATFNVGQEVPVLTGSQTTSGD---NIFNTVERK 482 Query: 543 DVGVTLKVIPHIGENGTVRLEVEQEVSDV---QSSKGQATDLVTNKRAIKTAVLAEHGQT 599 VG+ LKV P I E +V LE+EQEVS V SS N R + AVL G+T Sbjct: 483 TVGIKLKVKPQINEGDSVLLEIEQEVSSVADAASSTSSDLGATFNTRTVNNAVLVGSGET 542 Query: 600 VVLGGLISDNTSLTRQGIPGLSNIPYLGRLFRADSKSNEKRNLLVFIHPTIIGDAEDVRR 659 VV+GGL+ + S T +P L +IP +G LFR+ SK KRNL++FI PT+I D ++ R+ Sbjct: 543 VVVGGLLDKSVSDTADKVPLLGDIPVIGALFRSTSKKVSKRNLMLFIRPTVIRDRDEYRQ 602 Query: 660 ISQQRYNQLYSLQLSMDRNGNFAKLPEN 687 S +Y Q N + Sbjct: 603 ASSGQYTAFNDAQSKQRGKENNDAMLNQ 630
>TONBPROTEIN#Gram-negative bacterial tonB protein signature. Length = 239 Score = 28.8 bits (64), Expect = 0.015 Identities = 13/54 (24%), Positives = 20/54 (37%) Query: 145 VNREGMPQNIVTPKPAPIPEGVDIKAVPEPEPVAIKQPPSSVEQEKEQQKNASV 198 V P P+P PIPE V +P +P ++ ++Q V Sbjct: 61 VQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKPVKKVQEQPKRDV 114
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 76.0 bits (187), Expect = 4e-17 Identities = 50/149 (33%), Positives = 77/149 (51%), Gaps = 5/149 (3%) Query: 13 VNVGTIGHVDHGKTTLTAAI--ATICAKTYGGEAKDYSQIDSAPEEKARGITINTSHVEY 70 +N+G + HVD GKTTLT ++ + G K ++ D+ E+ RGITI T + Sbjct: 4 INIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSF 63 Query: 71 DSPIRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAATDGPMPQTREHILLSRQVGVPY 130 +D PGH D++ + + +DGAIL+ +A DG QTR R++G+P Sbjct: 64 QWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPT 123 Query: 131 IVVFLNKCDLVDDEELLELVEMEVRELLS 159 I F+NK D + L V +++E LS Sbjct: 124 I-FFINKIDQNGID--LSTVYQDIKEKLS 149
>SECETRNLCASE#Bacterial translocase SecE signature. Length = 127 Score = 76.1 bits (187), Expect = 8e-21 Identities = 41/126 (32%), Positives = 65/126 (51%), Gaps = 5/126 (3%) Query: 21 SAEVVTSGSPLDVVLWVIALALLIGAAMVNQYLPAYWPPANNIWVRVGVILACIVVALGL 80 + E SG L+ + WV+ +ALL+ A + N P +R ++ I A G+ Sbjct: 4 NTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLP-----LRALAVVILIAAAGGV 58 Query: 81 LYATHQGKGFIRLLKDARIELRRVTWPTKQETVTTSWQVLLVVVITSIVLWCFDYGLGWL 140 T +GK + ++AR E+R+V WPT+QET+ T+ V V + S++LW D L L Sbjct: 59 ALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTAVMSLILWGLDGILVRL 118 Query: 141 IKLIIG 146 + I G Sbjct: 119 VSFITG 124
>INVEPROTEIN#Salmonella/Shigella invasion protein E (InvE) signature. Length = 372 Score = 32.4 bits (73), Expect = 0.001 Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 30 LKGRDDQRLQKILELAEPFGISVQK-ASRDSLEKLAGL-PFHQGVVAAVRPHPVLNEKDL 87 L+ + ++IL+L ISV A D L + L P +V +R +L KDL Sbjct: 86 LEDEALPKAKQILKL-----ISVHGGALEDFLRQARSLFPDPSDLVLVLRE--LLRRKDL 138 Query: 88 DQLLQNNDQALLLALDQVTDPHNLGACIRTA 118 +++++ ++LL +++ TDP L A I A Sbjct: 139 EEIVRKKLESLLKHVEEQTDPKTLKAGINCA 169
>PREPILNPTASE#Type IV prepilin cysteine protease (C20) family signature. Length = 290 Score = 316 bits (811), Expect = e-111 Identities = 147/286 (51%), Positives = 189/286 (66%), Gaps = 2/286 (0%) Query: 1 MSDFIRYFSENLTALYCLVGILSLCIGSFLNVVIFRTPKMMEQEWKQECQMILHPDQPLI 60 M+ + + LV + SL IGSFLNVVI R P M+E+EW+ E + +PD + Sbjct: 1 MALLLELAHGLPWLYFSLVFLFSLMIGSFLNVVIHRLPIMLEREWQAEYRSYFNPDDEGV 60 Query: 61 ESEKLTLSYPASTCPHCHTPIRWYQNIPLISWLFLRGKCQSCKASISSRYPLVELLTMLC 120 + L P S CPHC+ PI +NIPL+SWL+LRG+C+ C+A IS+RYPLVELLT L Sbjct: 61 DEPPYNLMVPRSCCPHCNHPITALENIPLLSWLWLRGRCRGCQAPISARYPLVELLTALL 120 Query: 121 SLLVVVVFGATLHMLFGLVLTWILIALTFIDFDTQLLPDRFTLTLAGLGLAVNSFTIYVS 180 S+ V + L L+LTW+L+ALTFID D LLPD+ TL L GL N +VS Sbjct: 121 SVAVAMTLAPGWGTLAALLLTWVLVALTFIDLDKMLLPDQLTLPLLWGGLLFNLLGGFVS 180 Query: 181 PTQAIWGYIVGFLCLWIVYYIFKLITKKEGMGYGDFKLLAALGAWMGPMMLPLIVLLSSC 240 A+ G + G+L LW +Y+ FKL+T KEGMGYGDFKLLAALGAW+G LP+++LLSS Sbjct: 181 LGDAVIGAMAGYLVLWSLYWAFKLLTGKEGMGYGDFKLLAALGAWLGWQALPIVLLLSSL 240 Query: 241 VGAIIGII--LLRKRQENQPFAFGPYIAIAGWIAFLWGDQIMKVYL 284 VGA +GI LLR +++P FGPY+AIAGWIA LWGD I + YL Sbjct: 241 VGAFMGIGLILLRNHHQSKPIPFGPYLAIAGWIALLWGDSITRWYL 286
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 403 bits (1037), Expect = e-141 Identities = 120/409 (29%), Positives = 223/409 (54%), Gaps = 12/409 (2%) Query: 9 MPVFAYEGVDRKGIKLKGELPARNMALAKVTLRKQGITIRTIREKRKNIFEG-------L 61 M + Y+ +D +G K +G A + A+ LR++G+ ++ E R + + Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 62 LKKKVKPLDIAIFTRQLATMMKAGVPLVQAFEIVAEGLENPAMRDVVLGLKNEVEGGNTF 121 K ++ D+A+ TRQLAT++ A +PL +A + VA+ E P + ++ ++++V G++ Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 122 AGALRKYPQYFDNLFCSLIESGEQSGSLEIMLDRVAVYKEKSEVLKQKIKKAMKYPATVI 181 A A++ +P F+ L+C+++ +GE SG L+ +L+R+A Y E+ + ++ +I++AM YP + Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 182 VVAIVVTIILMVKVVPVFKDLFTSFGADLPAFTQLVVNMSNWMQDY--WFILILVIGAAI 239 VVAI V IL+ VVP + F LP T++++ MS+ ++ + W +L L+ G Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 240 AGFLEARKRSKRFRDQLDRLVLRLPIVGDLVYKAIIARYSRTLATTFAAGVPLIDALAST 299 + R ++ R R +L LP++G + ARY+RTL+ A+ VPL+ A+ + Sbjct: 241 FRVM---LRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRIS 297 Query: 300 AGATNNTVYEQAVLKIREDVSTGQQLNFAMRVSNRFPTMAIQMVAIGEESGALDEMLDKV 359 +N + + V G L+ A+ + FP M M+A GE SG LD ML++ Sbjct: 298 GDVMSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERA 357 Query: 360 ANYYESEVDHAVDGLTSMMEPLIMAILGILVGGLVIAMYLPIFQMGSVV 408 A+ + E + + EPL++ + +V +V+A+ PI Q+ +++ Sbjct: 358 ADNQDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>SECGEXPORT#Protein-export SecG membrane protein signature. Length = 110 Score = 95.0 bits (236), Expect = 6e-29 Identities = 51/105 (48%), Positives = 73/105 (69%), Gaps = 4/105 (3%) Query: 1 MHTFVLVVHIILAVLIIGLVLIQHGKGADAGASFGGGGAATVFGASGSGNFLTRVTAVLT 60 M+ +LVV +I+A+ ++GL+++Q GKGAD GASFG G +AT+FG+SGSGNF+TR+TA+L Sbjct: 1 MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFGSSGSGNFMTRMTALLA 60 Query: 61 ALFFVTSLSLAVFAKKQTTDAYSLKSVQTTNSAPASTPETSPNAP 105 LFF+ SL L +T +++ SAPA T +T P AP Sbjct: 61 TLFFIISLVLGNINSNKTNKGSEWENL----SAPAKTEQTQPAAP 101
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 86.8 bits (215), Expect = 1e-19 Identities = 82/393 (20%), Positives = 131/393 (33%), Gaps = 107/393 (27%) Query: 406 IMGHVDHGKTSLLDRIRRSKVAAGEAG------------------GITQHIGAYHVETDK 447 ++ HVD GKT+L + + + A E G GIT G + + Sbjct: 8 VLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWEN 67 Query: 448 GIITFLDTPGHAAFTAMRSRGAKATDIVVLVVAADDGVMPQTAEAIDHARAAGTPIIVAI 507 + +DTPGH F A R D +L+++A DGV QT R G P I I Sbjct: 68 TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFI 127 Query: 508 NKMDKESADPDRVLNEL---------------------TTKQIVPEQW------------ 534 NK+D+ D V ++ T EQW Sbjct: 128 NKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEGNDDLLE 187 Query: 535 -----------------------GGDVPVAMVSAHSGQGIDELLDLILIQSELMELKASG 571 PV SA + GID L+++I ++ G Sbjct: 188 KYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVIT--NKFYSSTHRG 245 Query: 572 EGAAQGVVIEARVDKGRGAVTSILVQNGTLNIGDLVL-AGSSYGRVRAM-SDENGQPIKS 629 + G V + + R + I + +G L++ D V + ++ M + NG+ K Sbjct: 246 QSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKI 305 Query: 630 AGPSIPVEILGLPDAPMAGDEVLVVNDEKKAREVADARADRERQKRIERQSAMRLENIMA 689 D +G+ V++ N+ K V +++RIE Sbjct: 306 -------------DKAYSGEIVILQNEFLKLNSVLGDTKLLPQRERIENPL--------- 343 Query: 690 SMGKKDVPTVNVVLKADVRGTLEALTAALNELS 722 P + ++ E L AL E+S Sbjct: 344 -------PLLQTTVEPSKPQQREMLLDALLEIS 369
>BCTERIALGSPF#Bacterial general secretion pathway protein F signature. Length = 408 Score = 418 bits (1077), Expect = e-147 Identities = 193/406 (47%), Positives = 267/406 (65%), Gaps = 5/406 (1%) Query: 1 MPAYQFTALDASGKQQKGVLEGDSARQIRQQLRDREWTPIAVDPVEQKDKRQGN----TW 56 M Y + ALDA GK+ +G E DSARQ RQ LR+R P++VD ++ G+ Sbjct: 1 MAQYHYQALDAQGKKCRGTQEADSARQARQLLRERGLVPLSVDENRGDQQKSGSTGLSLR 60 Query: 57 FQKKVTAYDLALMTRQLSVLVAAAIPLEEALRAVAKQSEKAHVQNLLLSVRSKVLEGHSL 116 + +++ DLAL+TRQL+ LVAA++PLEEAL AVAKQSEK H+ L+ +VRSKV+EGHSL Sbjct: 61 RKIRLSTSDLALLTRQLATLVAASMPLEEALDAVAKQSEKPHLSQLMAAVRSKVMEGHSL 120 Query: 117 AQGMQ-QSGRFPDLYIATIAAGERSGHLDLILDQLADYTENRFAMQKKVQGAMIYPIILM 175 A M+ G F LY A +AAGE SGHLD +L++LADYTE R M+ ++Q AMIYP +L Sbjct: 121 ADAMKCFPGSFERLYCAMVAAGETSGHLDAVLNRLADYTEQRQQMRSRIQQAMIYPCVLT 180 Query: 176 LMSFAIVMGLMTYVVPDIVKTFDQSKEALPWITVALMKASDFIRLAWPFLMSFGVIAIIL 235 +++ A+V L++ VVP +V+ F K+ALP T LM SD +R P+++ + + Sbjct: 181 VVAIAVVSILLSVVVPKVVEQFIHMKQALPLSTRVLMGMSDAVRTFGPWMLLALLAGFMA 240 Query: 236 FIRFLRTHAGHYAFDRLTLRLPLFGKLSRGINSARFASTLSILTQSGVPLVDALRIGAAV 295 F LR +F R L LPL G+++RG+N+AR+A TLSIL S VPL+ A+RI V Sbjct: 241 FRVMLRQEKRRVSFHRRLLHLPLIGRIARGLNTARYARTLSILNASAVPLLQAMRISGDV 300 Query: 296 SSNWVIRDAINHAAEKVTEGGNLGTQLERCGYFPPMMVQMIRSGETSGELDRMLERASTM 355 SN R ++ A + V EG +L LE+ FPPMM MI SGE SGELD MLERA+ Sbjct: 301 MSNDYARHRLSLATDAVREGVSLHKALEQTALFPPMMRHMIASGERSGELDSMLERAADN 360 Query: 356 QDREVTTFISTLLALLEPLMLVLMAAIVLVIVIAVMLPIVNMNNMI 401 QDRE ++ ++ L L EPL++V MAA+VL IV+A++ PI+ +N ++ Sbjct: 361 QDREFSSQMTLALGLFEPLLVVSMAAVVLFIVLAILQPILQLNTLM 406
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 148 bits (376), Expect = 7e-49 Identities = 63/137 (45%), Positives = 81/137 (59%), Gaps = 6/137 (4%) Query: 26 MIRPKRVSGFTLIEVMVVIVILGVLAALIVPNVMGRGEKAKVDTTQITLKGVAGALDQYK 85 M + GFTL+E+MVVIVI+GVLA+L+VPN+MG EKA + + ALD YK Sbjct: 1 MRATDKQRGFTLLEIMVVIVIIGVLASLVVPNLMGNKEKADKQKAVSDIVALENALDMYK 60 Query: 86 LDNGHFPTMQEGGLDALVNQPATA---KNWLPGGYVKGGYPKDSWENDIQYVIPGTEGRA 142 LDN H+PT + GL++LV P N+ GY+K P D W ND V PG G A Sbjct: 61 LDNHHYPTTNQ-GLESLVEAPTLPPLAANYNKEGYIK-RLPADPWGNDYVLVNPGEHG-A 117 Query: 143 FDLYSFGADGKAGGEGN 159 +DL S G DG+ G E + Sbjct: 118 YDLLSAGPDGEMGTEDD 134
>PF07520#Virulence protein SrfB Length = 1041 Score = 27.2 bits (60), Expect = 0.018 Identities = 24/106 (22%), Positives = 41/106 (38%), Gaps = 13/106 (12%) Query: 1 MRALFLSDDVNQFHWSVLKSVLLILSLL-PISQGILSLWQMSDASSQIIVGFIALSIFSA 59 MR LF D Q +V + + +L P+++ ILS + ++ + +I + + Sbjct: 668 MRELFGGDIGGQEQQTVQRRRQFSIRVLVPLAEAILSACEDAEEADRIDIP------VAD 721 Query: 60 VLILSFYSALKATVMKLNAQQEISTLEQVIFSIYGYL--PMLSLAA 103 VL L + + + QV I YL P L A Sbjct: 722 VLGLVPTPV----GEEGDEEGHEDASPQVTDEILDYLEKPATQLGA 763
>PF06580#Sensor histidine kinase Length = 349 Score = 30.6 bits (69), Expect = 0.015 Identities = 27/139 (19%), Positives = 45/139 (32%), Gaps = 22/139 (15%) Query: 61 RSAKQAF----MLGWAYGLGLWFVGAFWLYTSIHVYGDTNAILSVLMIAIMALVMGLFTA 116 R A + + +GW F A YG + IAI + + L A Sbjct: 6 RQANKYYWYCQGIGWGVYTLTGFGFASL-------YGSPKLHSMIFNIAISLMGLVLTHA 58 Query: 117 IQTWFYRRFFPETPLTFAPIWIVFEWAKTWVFTGFPWLFAGYAFTE--RFLDH-----YA 169 +++ R+ + L I+ V G W A + F++ Sbjct: 59 YRSFIKRQGW----LKLNMGQIILRVLPACVVIGMVWFVANTSIWRLLAFINTKPVAFTL 114 Query: 170 PLFGVFGVSFVVITLACAL 188 PL + VV+T +L Sbjct: 115 PLALSIIFNVVVVTFMWSL 133
>PF01206#SirA family protein Length = 76 Score = 84.4 bits (209), Expect = 2e-25 Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 5/75 (6%) Query: 13 QLNTRGLRCPEPVMMLHQAIRKSKSGDIVEVFATDPSTSWDIPKFCTHLGHELLLQEEHL 72 L+ GL CP P++ + + +G+++ V ATDP + D F GHELL Q+E Sbjct: 7 SLDATGLNCPLPILKAKKTLATMNAGEVLYVMATDPGSVKDFESFSKQTGHELLEQKEED 66 Query: 73 DANELKEYHYLIQKG 87 YH+ +++ Sbjct: 67 G-----TYHFRLKRA 76
>MALTOSEBP#Maltose binding protein signature. Length = 396 Score = 28.9 bits (64), Expect = 0.013 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 4/68 (5%) Query: 76 LYPVHADALPWIVHTL-YPVQVEQFFILYPNPEPHNPAQRWLNMPFFEFLLSRLKPEGTI 134 LYP DA+ + + YP+ VE ++Y NP + W +P + LK +G Sbjct: 115 LYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPALD---KELKAKGKS 171 Query: 135 TLASNIPE 142 L N+ E Sbjct: 172 ALMFNLQE 179
>SECFTRNLCASE#Bacterial translocase SecF protein signature. Length = 333 Score = 88.0 bits (218), Expect = 5e-21 Identities = 40/180 (22%), Positives = 85/180 (47%), Gaps = 12/180 (6%) Query: 458 VVGPSLGQENIDKGILSTEVGFILVAIWMIVFFRL-FGLIANFALVFNLAMILTVMSWIG 516 VGP + E + + S +++ ++ V F F L A ALV ++ + + + + + Sbjct: 142 SVGPKVSGELVWTAVWSLLAATVVIMFYIWVRFEWQFALGAVVALVHDVLLTVGLFAVLQ 201 Query: 517 ASLTLPGIAGIVITIGMAVDANVLICERIREEI-KWGASPKQAIVAGYDRAYN-----TI 570 L +A ++ G +++ V++ +R+RE + K+ P + ++ + + N T+ Sbjct: 202 LKFDLTTVAALLTITGYSINDTVVVFDRLRENLIKYKTMPLRDVM---NLSVNETLSRTV 258 Query: 571 FDSNLTTFLVAFILFAIGTGPIKGFAVTLMIGIVCSMFTAITVTRAIVQLIYGKRRNLKK 630 +TT L + G I+GF ++ G+ ++++ V + IV L G RN +K Sbjct: 259 MTG-MTTLLALVPMLIWGGDVIRGFVFAMVWGVFTGTYSSVYVAKNIV-LFIGLDRNKEK 316
>PF06580#Sensor histidine kinase Length = 349 Score = 43.3 bits (102), Expect = 1e-06 Identities = 22/109 (20%), Positives = 42/109 (38%), Gaps = 24/109 (22%) Query: 298 LIQNLVSNALK--FTQTDGTGKVIIDAIKVADHVEITIRDTGMGMSESKIRDIFQPRITV 355 L+Q LV N +K Q GK+++ K V + + +TG ++ Sbjct: 259 LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTGSLALKNT----------- 307 Query: 356 SFRGTSGEKGAGLGLVLCKRFVDLNLG---AISVTSKEGEGTVFTVTLP 401 ++ G GL + + + G I ++ K+G+ V +P Sbjct: 308 -------KESTGTGLQNVRERLQMLYGTEAQIKLSEKQGKVNA-MVLIP 348
>FLGMOTORFLIG#Flagellar motor switch protein FliG signature. Length = 344 Score = 34.0 bits (78), Expect = 0.003 Identities = 32/166 (19%), Positives = 59/166 (35%), Gaps = 33/166 (19%) Query: 407 RHKVSEQFKKLIQE----EVTSPDETDTELE---------QQLNAILDETAQNLVHEFWQ 453 ++ E+ + L E E + + D L + + + A+ L+ + Sbjct: 38 KYLSQEEIESLTFEIAKLETITSELKDNVLLEFKELMMAQEFIQKGGIDYARELLEKSLG 97 Query: 454 S----NALKRLPSKAVQRLKDFW----PHFIEAILQSEHPQMAFMRLMPLIESVMRR--- 502 + + + L S R +F P I +Q EHPQ + LI S + Sbjct: 98 TQKAVDIINNLGSALQSRPFEFVRRADPANILNFIQQEHPQT-----IALILSYLDPQKA 152 Query: 503 TVYLVMLMES--RGAMQRLVKMATVSPWICEELTQYPVLLDEFLSM 546 + L L +R+ M SP + E+ + VL + S+ Sbjct: 153 SFILSSLPTEVQTNVARRIALMDRTSPEVVREVER--VLEKKLASL 196
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 29.5 bits (66), Expect = 0.004 Identities = 12/25 (48%), Positives = 16/25 (64%) Query: 7 GFTLIEFITVSAIIAILVSLGLPAY 31 GFTL+E + V II +L SL +P Sbjct: 9 GFTLLEIMVVIVIIGVLASLVVPNL 33
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 134 bits (338), Expect = 2e-38 Identities = 89/367 (24%), Positives = 144/367 (39%), Gaps = 43/367 (11%) Query: 1 MKLSRIALATMLVAAPLAAANAGVTVTPLLLGYTFQDSQHNNGGDKGNLTNGPELQDDLF 60 MK + IA+A L A A T G SQ+++ G N NGP ++ L Sbjct: 1 MKKTAIAIAVALAGFATVAQAAPKDNT-WYTGAKLGWSQYHDTGFINN--NGPTHENQLG 57 Query: 61 VGAALGVELTPWLGFEAEYN-----QVKGDVDGAAAGAEYKQQQINGNFYVTSDLITKNY 115 GA G ++ P++GFE Y+ KG V+ A A+ Q + +T DL Sbjct: 58 AGAFGGYQVNPYVGFEMGYDWLGRMPYKGSVENGAYKAQGVQLTAKLGYPITDDL----- 112 Query: 116 DSKIKPYVLLGAGHYKYDFDGVDRGYRGNKEEGTLGNAGIGAFWRLNDALSLRTEARATY 175 Y LG ++ D Y N + G G + + ++ R E + T Sbjct: 113 ----DIYTRLGGMVWRADTK--SNVYGKNHDTGVSPVFAGGVEYAITPEIATRLEYQWTN 166 Query: 176 N-ADEEFWNYTA---LAGLNVVLGGHLKPAAPVVEVAPVEPAPVVQPQQPQELTEDLNME 231 N D + L V AAPVV AP V T+ ++ Sbjct: 167 NIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQ--------TKHFTLK 218 Query: 232 LRVFFDTNKSNIKDQYKPEIAKVAEKLVEY--PNATARIDGHTDNTGPRKLNERLSLARA 289 V F+ NK+ +K + + + ++ +L + + + G+TD G N+ LS RA Sbjct: 219 SDVLFNFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRA 278 Query: 290 NSVKSALVNEYNIDPARLATQGFAWDQPIADNST---------KEGRAMNRRVFATITGS 340 SV L+++ I +++ +G P+ N+ + A +RRV + G Sbjct: 279 QSVVDYLISK-GIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGI 337 Query: 341 RTVTVQP 347 + V QP Sbjct: 338 KDVVTQP 344
>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family signature. Length = 639 Score = 161 bits (410), Expect = 1e-44 Identities = 99/442 (22%), Positives = 178/442 (40%), Gaps = 69/442 (15%) Query: 6 NLRNIAIIAHVDHGKTTLVDKLLQQSGALGDRAGEIER---VMDSNALESERGITILAKN 62 + NI ++AHVD GKTTL + LL SGA+ G +++ D+ LE +RGITI Sbjct: 2 KIINIGVLAHVDAGKTTLTESLLYNSGAI-TELGSVDKGTTRTDNTLLERQRGITIQTGI 60 Query: 63 TSIKWLDKRTDTEYRINIVDTPGHADFGGEVERVMSMVDCVLLLVDSQEGPMPQTRFVTQ 122 TS +W + ++NI+DTPGH DF EV R +S++D +LL+ +++G QTR + Sbjct: 61 TSFQWEN------TKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFH 114 Query: 123 KAFARGLKPIVIINKVDKPSARPDWVIDQVFD-------------LFDNLGATD----EQ 165 G+ I INK+D+ V + + L+ N+ T+ EQ Sbjct: 115 ALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQ 174 Query: 166 LDFPIVYASGL--RGVAGPSP--EELAEDMT-----------------------PLFETI 198 D I L + ++G S EL ++ + L E I Sbjct: 175 WDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAKNNIGIDNLIEVI 234 Query: 199 VDIVEPPAVDADGPFQMQISSLDYNSFVGVIGVGRIQRGSVKLNTPVTVIDKEGNTRNGR 258 + ++ ++Y+ + R+ G + L V + +KE + Sbjct: 235 TNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKI----K 290 Query: 259 ILKIMGYHGLERIDVESASAGDIVCITGIDALNISDTICDPKNVEALPPLSVDEPTVSMT 318 I ++ E ++ A +G+IV + + L ++ + D K + + P + T Sbjct: 291 ITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQTT 349 Query: 319 FQVNNSPFAGKEGKFVTSRNIRERLDRELIHNVALRVEDTDSPDRFKVSGRGELHLSVLI 378 + + + + + L LR + +S G++ + V Sbjct: 350 VEPSKPQQREMLLDALLEISDSDPL---------LRYYVDSATHEIILSFLGKVQMEVTC 400 Query: 379 ENMRRE-GFELGVSRPQVIIKE 399 ++ + E+ + P VI E Sbjct: 401 ALLQEKYHVEIEIKEPTVIYME 422 Score = 39.5 bits (92), Expect = 4e-05 Identities = 10/79 (12%), Positives = 28/79 (35%), Gaps = 1/79 (1%) Query: 406 EPYENVTFDVEEQHQGAVMEQMGHRKGEMTNMEVDGKGRIRIEATVPSRGLIGFRSEFLT 465 EPY + +++ + + ++ + + +P+R + +RS+ Sbjct: 537 EPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKN-NEVILSGEIPARCIQEYRSDLTF 595 Query: 466 MTSGTGIMTSSFSHYGPVK 484 T+G + + Y Sbjct: 596 FTNGRSVCLTELKGYHVTT 614
>MECHCHANNEL#Bacterial mechano-sensitive ion channel signature. Length = 136 Score = 129 bits (326), Expect = 1e-41 Identities = 75/143 (52%), Positives = 100/143 (69%), Gaps = 11/143 (7%) Query: 1 MSIIQEFREFAVKGNMIDLAVGVIIGGAFGKIVDSLVKDIIMPLITVITGGGVDFTQKFV 60 MSII+EFREFA++GN++DLAVGVIIG AFGKIV SLV DIIMP + ++ GG+DF Q V Sbjct: 1 MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPPLGLLI-GGIDFKQFAV 59 Query: 61 VLGNNPDNLQSLDALQKAGVNVLTYGNFLTILINFIILAWVVFLMVKLINRMRRKQEEAP 120 L DA V+ YG F+ + +F+I+A+ +F+ +KLIN++ RK+EE Sbjct: 60 TLR---------DAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKLNRKKEEPA 110 Query: 121 AAPAPTPEDIALLREIRDELKNR 143 AAPAPT E++ LL EIRD LK + Sbjct: 111 AAPAPTKEEV-LLTEIRDLLKEQ 132
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 26.2 bits (57), Expect = 0.013 Identities = 10/25 (40%), Positives = 15/25 (60%) Query: 52 ADAPADHPNPSAQPATPNNSTPDSN 76 A+ PA++P P+ P T N PD + Sbjct: 334 AENPANNPAPNENPGTRPNPEPDPD 358 Score = 24.7 bits (53), Expect = 0.049 Identities = 13/33 (39%), Positives = 16/33 (48%), Gaps = 2/33 (6%) Query: 46 DHKPDAADAPADHPNPSAQPAT--PNNSTPDSN 76 D P +A+AP P P PA NN P+ N Sbjct: 314 DLTPGSAEAPNAQPLPEVSPAENPANNPAPNEN 346
>PF05616#Neisseria meningitidis TspB protein Length = 501 Score = 31.6 bits (71), Expect = 0.009 Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 14/67 (20%) Query: 503 VDTSLVPKPVSSSSDHDVPTSF---DVDPQNKPLNNPYGSKGEGD--------DISP--- 548 VD ++P+P + + P + +V P P NNP ++ G D++P Sbjct: 305 VDVQVIPRPDLTPGSAEAPNAQPLPEVSPAENPANNPAPNENPGTRPNPEPDPDLNPDAN 364 Query: 549 PQSDDQP 555 P +D QP Sbjct: 365 PDTDGQP 371
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 129 bits (326), Expect = 2e-35 Identities = 61/416 (14%), Positives = 137/416 (32%), Gaps = 83/416 (19%) Query: 47 PTKKSTLFIMFFVLLVGIGLIMWAWRIGPFHTMIEQTDNSYVKGKTTVLSSQINGYIKEV 106 P + + +F++ + + + +G + G++ + N +KE+ Sbjct: 52 PVSRRPRLVAYFIMGFLVIAFILSV-LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEI 110 Query: 107 LVKDFDDVKQGQPLLYIDATTYDQKVTQA------------------------------- 135 +VK+ + V++G LL + A + + Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKL 170 Query: 136 ---------------------ESAVAQAQNTLANQTQTIAQREADIIAAQAQVDQAQAEY 174 + + QN + + ++ A+ + A++++ + Sbjct: 171 PDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLS 230 Query: 175 QLSLDQLRRYQQLGDSGAASKS---EQDQIAATAKNNLAALKK--AKANVKVANEALKTA 229 ++ +L + L A +K EQ+ A N L K + ++ + + Sbjct: 231 RVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQ 290 Query: 230 QVAE----------VGLNAQVTSAQAQLDQAKTTKNYSVITAPMDGQLGEV-TPRIGQYV 278 V + + +L + + + SVI AP+ ++ ++ G V Sbjct: 291 LVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVV 350 Query: 279 AAGSQLLYLIPNQT--WVIANFKETQIAHMKIGQPATFTVDALDHQKF---KGHIEQISP 333 L+ ++P V A + I + +GQ A V+A + ++ G ++ I+ Sbjct: 351 TTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGYLVGKVKNINL 410 Query: 334 AAGSEFSVLKADNATGNFTKVVQRISVRIAIDPNQDELKRLRPGMSVITSVDTSSR 389 A D G V+ I N++ L GM+V + T R Sbjct: 411 DAIE-------DQRLGLVFNVIISIEENCLSTGNKNI--PLSSGMAVTAEIKTGMR 457
>TCRTETB#Tetracycline resistance protein TetB signature. Length = 458 Score = 40.2 bits (94), Expect = 2e-05 Identities = 53/314 (16%), Positives = 108/314 (34%), Gaps = 26/314 (8%) Query: 45 FIALTAGLSNGFITANLPQLQGEYGLTPVEAAWLPAAYVMANVSSNLILFKARQQYGLRL 104 ++ + L+ + +LP + ++ P W+ A+++ + K Q G++ Sbjct: 21 ILSFFSVLNEMVLNVSLPDIANDFNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKR 80 Query: 105 FTEIGLLAFIVVMVLHIFVQNY-HMAVLVRFISGMVAAPLSSLGMYYIMQSFSNAHRLKG 163 G++ V+ ++ + ++ RFI G AA +L M + + +R K Sbjct: 81 LLLFGIIINCFGSVIGFVGHSFFSLLIMARFIQGAGAAAFPALVMVVVARYIPKENRGKA 140 Query: 164 LYIGFGFGQLGVPLAWIISPALVTVNDWTVLYTFELGLAVCCYAMVVSLKLPRSLRIAVF 223 + +G + I + W+ L + + ++ LK ++ Sbjct: 141 FGLIGSIVAMGEGVGPAIGGMIAHYIHWSYLLLIPMITIITVPFLMKLLKKEVRIK---- 196 Query: 224 ERQDIFTFLLLAPGFACLCAVLTQGPLLWWFDSPWLAYVLMSGFVLLVLGFFYEHHRR-- 281 DI +L++ G +L F +L F +H R+ Sbjct: 197 GHFDIKGIILMSVGIVFF--MLFTTSYSISFLIVS----------VLSFLIFVKHIRKVT 244 Query: 282 NPLIMTRWLGTAAVLR------FIFGAFCLRFLLSEQSYAAVNFLKTVGMGPD-QFVGLY 334 +P + + IFG + V+ L T +G F G Sbjct: 245 DPFVDPGLGKNIPFMIGVLCGGIIFGTVAGFVSMVPYMMKDVHQLSTAEIGSVIIFPGTM 304 Query: 335 SIIFFGMLAGVLFS 348 S+I FG + G+L Sbjct: 305 SVIIFGYIGGILVD 318
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 43.5 bits (102), Expect = 1e-07 Identities = 17/66 (25%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 16 RAAKNREDLLEAAVEMFKTHGM-MVPLQVIIDHANVGRATFYRNFADRKMLVYALLEQSL 74 A + R+ +L+ A+ +F G+ L I A V R Y +F D+ L + E S Sbjct: 8 EAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWELSE 67 Query: 75 VKLKQR 80 + + Sbjct: 68 SNIGEL 73
>adhesinb#Adhesin B signature. Length = 310 Score = 28.7 bits (64), Expect = 0.002 Identities = 9/20 (45%), Positives = 13/20 (65%) Query: 12 MKKISIMIILLSSFTALTAC 31 MKK +++LL +F L AC Sbjct: 1 MKKCRFLVLLLLAFVGLAAC 20
>ACRIFLAVINRP#Acriflavin resistance protein family signature. Length = 1034 Score = 779 bits (2012), Expect = 0.0 Identities = 280/1037 (27%), Positives = 496/1037 (47%), Gaps = 33/1037 (3%) Query: 5 RISVKYPVFTIMMMFCLMVLGLASWQRMSVEEFPDVDFPFVVIYTNYPGASPEAVESEIT 64 ++ P+F ++ LM+ G + ++ V ++P + P V + NYPGA + V+ +T Sbjct: 3 NFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVT 62 Query: 65 KKLEDQINTISGLKQITSQS-SEGLSMIVAEFNLDVASSVAAQDVRDKIAVAKANFRDEI 123 + +E +N I L ++S S S G I F +A V++K+ +A E+ Sbjct: 63 QVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEV 122 Query: 124 EDPVVERYDPASSAILSVVFETN--QMSLRDFSSYIDQRILPQLRTTPGVGTVNLLGEAK 181 + + +SS ++ F ++ + D S Y+ + L GVG V L G A+ Sbjct: 123 QQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG-AQ 181 Query: 182 RQIRIIIHPQKLQSYGIGIDQVINTLKNENVEIPGGTLKQPDS------ELVIEIQSKVI 235 +RI + L Y + VIN LK +N +I G L + I Q++ Sbjct: 182 YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTRFK 241 Query: 236 HPYGFGDLVI-ANKNGVPIYLKQVADVQDTQAELETGAFLNGKTAVAVDILRSSDANVIE 294 +P FG + + N +G + LK VA V+ A +NGK A + I ++ AN ++ Sbjct: 242 NPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANALD 301 Query: 295 VVDNTYKVLDKIKQQLPQGASLHVVVDTSKGIRASIKDVARTIIEGAALAVLIVLLFLGS 354 L +++ PQG + DT+ ++ SI +V +T+ E L L++ LFL + Sbjct: 302 TAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLFLQN 361 Query: 355 FRSTVITGLTLPIALLGTLTFIWAFGFSINMMTLLALSLCIGLLIDDAIVVRENIVRH-A 413 R+T+I + +P+ LLGT + AFG+SIN +T+ + L IGLL+DDAIVV EN+ R Sbjct: 362 MRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVERVMM 421 Query: 414 DMGKDHVTAALDGTKEIGLAVLATTLTIVAVFLPVAFMGGIIGRFFFQFGVTVSTAVLIS 473 + A +I A++ + + AVF+P+AF GG G + QF +T+ +A+ +S Sbjct: 422 EDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAMALS 481 Query: 474 MFVSFTLDPMLSAHWQERKTNKPPSRIKRFFNWISQKLDHLSHVYERLLKLALCFRFITL 533 + V+ L P L A + + + FF W + DH + Y + L L Sbjct: 482 VLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYL 541 Query: 534 LIAVVSLIGALGLSKLIGTEFVPTPDKGEVRIKFETPVDASLDYTQAKLDQVTQII--TQ 591 LI + + G + L + + F+P D+G + P A+ + TQ LDQVT + Sbjct: 542 LIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNE 601 Query: 592 FAYVKSTYGVIN-GVTDRGKNHATLRVTVTPRTERS---QTLIEINNQFRQRLQRVAGIT 647 A V+S + V + + +N V++ P ER+ + + ++ + L ++ Sbjct: 602 KANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGKIRDGF 661 Query: 648 VTSV---ASADETVSGGQKPIMISIKGPDLNELQAISDRFMTEMEK-IKGIVDLESSLKE 703 V A + + G +I G + L ++ + + +V + + E Sbjct: 662 VIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLE 721 Query: 704 PKPTLSVQVNRVLASDLGLSVNQIANTVRPLIAGDNVTTWEDDRGETYNVNLRLAEHSRM 763 ++V++ A LG+S++ I T+ + G V + D G + ++ RM Sbjct: 722 DTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDR-GRVKKLYVQADAKFRM 780 Query: 764 LPRDVENLYLTSSKIDSNNQAILVPLASVAKFEQTLGASQINRRDLAREVLVEAN-TSGR 822 LP DV+ LY+ S+ +VP ++ G+ ++ R + + ++ G Sbjct: 781 LPEDVDKLYVRSAN------GEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGT 834 Query: 823 PAGDIGKDIEQLQKNFKLPAGYSFDTQGANADMAESAGYALTAITLSIVFIYIVLGSQFN 882 +GD +E L KLPAG +D G + S A + +S V +++ L + + Sbjct: 835 SSGDAMALMENLAS--KLPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYE 892 Query: 883 SFIHPAAIMASLPLSLIGVFLALFLFNSTMNLFSIIGIIMLMGLVTKNAILLIDFIKKAM 942 S+ P ++M +PL ++GV LA LFN +++ ++G++ +GL KNAIL+++F K M Sbjct: 893 SWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLM 952 Query: 943 DR-GENRYDAIIQAGKTRLRPILMTTSAMVMGMVPLALGLGEGGEQSAPMAHAVIGGVIT 1001 ++ G+ +A + A + RLRPILMT+ A ++G++PLA+ G G + V+GG+++ Sbjct: 953 EKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVS 1012 Query: 1002 STLLTLVVVPVIFTYLD 1018 +TLL + VPV F + Sbjct: 1013 ATLLAIFFVPVFFVVIR 1029
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 44.0 bits (104), Expect = 5e-07 Identities = 24/135 (17%), Positives = 52/135 (38%), Gaps = 12/135 (8%) Query: 96 KNQVLVRLNNQDNVARLAQARANLASAQAQAELAHNLMLRKKRLLDQGFISRVEYEQSQV 155 Q + + + + +A L ++Q E + +L K + + Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQL------VTQLFKN 298 Query: 156 DYKGQLETANAQKANLDIAL-KADQDG---IIRSPLTGVITKRQV-EPGQTVSAGQTLFE 210 + +L L + L K ++ +IR+P++ + + +V G V+ +TL Sbjct: 299 EILDKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMV 358 Query: 211 IV-DPKQLEIQAKLP 224 IV + LE+ A + Sbjct: 359 IVPEDDTLEVTALVQ 373 Score = 33.3 bits (76), Expect = 0.002 Identities = 23/141 (16%), Positives = 51/141 (36%), Gaps = 11/141 (7%) Query: 54 TGELQTKIPFTGTIRAVNQS-SIQAQVTATATQVNADVGEAVTKNQVLVRLNNQDNVARL 112 G+++ G + +S I+ + ++ GE+V K VL++L A Sbjct: 77 LGQVEIVATANGKLTHSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADT 136 Query: 113 AQARANLASAQAQAE--LAHNLMLRKKRLLDQGF--------ISRVEYEQSQVDYKGQLE 162 + +++L A+ + + + +L + +S E + K Q Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196 Query: 163 TANAQKANLDIALKADQDGII 183 T QK ++ L + + Sbjct: 197 TWQNQKYQKELNLDKKRAERL 217 Score = 30.6 bits (69), Expect = 0.010 Identities = 6/33 (18%), Positives = 15/33 (45%) Query: 182 IIRSPLTGVITKRQVEPGQTVSAGQTLFEIVDP 214 I+ ++ + V+ G++V G L ++ Sbjct: 98 EIKPIENSIVKEIIVKEGESVRKGDVLLKLTAL 130
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 79.5 bits (196), Expect = 1e-20 Identities = 31/119 (26%), Positives = 55/119 (46%), Gaps = 2/119 (1%) Query: 8 IKIMVIDDSKTIRRTAETLLQKEGYTVVTATDGFEALSKIAQTNPDIIFVDIMMPRLDGY 67 I+V DD IR L + GY V ++ IA + D++ D++MP + + Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 68 QTCALIKNSQNYQHIPVIMLSSKDGLFDQAKGRIVGSDEYLIKPFSKDELLTAIRNHVS 126 IK + +PV+++S+++ K G+ +YL KPF EL+ I ++ Sbjct: 64 DLLPRIKKA--RPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALA 120
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.4 bits (201), Expect = 2e-21 Identities = 38/116 (32%), Positives = 55/116 (47%), Gaps = 2/116 (1%) Query: 2 ARILIVDDSPTETYRFRDILTRHGYQVLEATNGADGVTLAQAEQPDLVLMDVVMPGVNGF 61 A IL+ DD L+R GY V +N A A DLV+ DVVMP N F Sbjct: 4 ATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAF 63 Query: 62 QATRQICRGEQTKHIPVVIVSTKDQATDRIWGKRQGAREYLTKPIDENQLIEVIQQ 117 +I + +PV+++S ++ I +GA +YL KP D +LI +I + Sbjct: 64 DLLPRI--KKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGR 117
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 93.4 bits (232), Expect = 1e-21 Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 2/125 (1%) Query: 1306 DRSLIMVVDDSVTVRKVTSRLLERQGYDVVTAKDGQDALEQLEHIRPSLILLDIEMPQMD 1365 + I+V DD +R V ++ L R GYDV + + L++ D+ MP + Sbjct: 2 TGATILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDEN 61 Query: 1366 GFELTRYIRQHSILNSLPIIMITSRTGEKYREIAQQLGVDDYMGKPFQEDDLLTKIQNLL 1425 F+L I++ LP+++++++ A + G DY+ KPF +L+ I L Sbjct: 62 AFDLLPRIKKARP--DLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRAL 119 Query: 1426 AQNKA 1430 A+ K Sbjct: 120 AEPKR 124
>RTXTOXIND#Gram-negative bacterial RTX secretion protein D signature. Length = 478 Score = 53.3 bits (128), Expect = 4e-09 Identities = 33/220 (15%), Positives = 84/220 (38%), Gaps = 17/220 (7%) Query: 272 LESTSALFQRLIQQSTPLQTEWQVAEKKLAELKMTLEQKQSLYQQNSTTLTQLEQQKVQT 331 L + A L QS+ LQ + ++ + L + L + + +++V Sbjct: 127 LTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLR 186 Query: 332 KERLQLSEIQLESLQEQQEQQVEHLHHAEQQTQMAEQRHIDLQAQHKQTQQQFDQLKT-- 389 L + Q + Q Q+ Q+ +L + R + + + + D + Sbjct: 187 --LTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLL 244 Query: 390 --------QIEKQQQQKSQMSAQIEQLRKSVERLEQQKQTLQQQIGQVTAQVQHEDLERL 441 + +Q+ + + ++ + +E++E + + +++ VT ++E L++L Sbjct: 245 HKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKL 304 Query: 442 KQQLHNDEEL-----SAQQQQQLEQFKQAIDVTLQKQITF 476 +Q N L +++QQ + + V +Q+ Sbjct: 305 RQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKVH 344 Score = 37.5 bits (87), Expect = 3e-04 Identities = 19/205 (9%), Positives = 80/205 (39%), Gaps = 13/205 (6%) Query: 236 QSSQSLILQQTYTIE-MNTLGEQFKLVRSELNTIEHDLESTSALFQRLIQQSTPLQTEWQ 294 +QS +LQ L +L + + + + + +++ ++ ++ ++ Sbjct: 137 LKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFS 196 Query: 295 VAEKKLAELKMTLEQKQSLYQQNSTTLTQLEQQKVQTKERLQLSEIQLESLQEQQEQQVE 354 + + + ++ L++K++ + + E ++ + +L+ +Q Sbjct: 197 TWQNQKYQKELNLDKKRAERLTVLARINRYENL-------SRVEKSRLDDFSSLLHKQAI 249 Query: 355 HLHHAEQQTQMAEQRHIDLQAQHKQTQQQFDQLKTQIEKQQQQKSQMSAQI-EQLRKSVE 413 H +Q E ++++ + + + Q +Q++++I +++ ++ ++ + Sbjct: 250 AKHAVLEQ----ENKYVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLR 305 Query: 414 RLEQQKQTLQQQIGQVTAQVQHEDL 438 + L ++ + + Q + Sbjct: 306 QTTDNIGLLTLELAKNEERQQASVI 330 Score = 32.5 bits (74), Expect = 0.011 Identities = 20/168 (11%), Positives = 46/168 (27%), Gaps = 22/168 (13%) Query: 647 LDEIAQEHSQLETQRDMVAKKLETLALELAEQQKQFQDLQQDAKQRRHAIQKNELEVAKK 706 ++ +L + E + + ++QF Q Q+ + K E Sbjct: 160 IELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTV 219 Query: 707 QASAQAFVLQNQQLQQQLN----------------------QVDLQLEEDAMQRDDSEID 744 A + ++ + +L+ V+ E + +I+ Sbjct: 220 LARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIE 279 Query: 745 LHALQLKLETHLPNFKLQQLEWETLTDQLDDALQHWQQRQQERELLRR 792 L K E L + + L D+ + + E + Sbjct: 280 SEILSAKEEYQLVTQLFKNEILDKLRQTTDNIGLLTLELAKNEERQQA 327 Score = 31.0 bits (70), Expect = 0.036 Identities = 28/210 (13%), Positives = 71/210 (33%), Gaps = 21/210 (10%) Query: 800 QMELLEKDISFLKTQLQQIMVQMDQAKKFVDPIQLELPALESAFSEQYQQTETLQKKWKE 859 ++ L + LKTQ + +++Q + + +EL L + + ++ Sbjct: 126 KLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNVSEEEVL 185 Query: 860 WQLELNHVQEKQQHLTEQRHQTEQRDEKVRADLEEKRLAWQAAKSDLEHYQEQLAALNAQ 919 L ++E+ Q++Q E +K RA+ ++ + +L ++ Sbjct: 186 RLTSL--IKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSRLDDFSSL 243 Query: 920 IQPNLTLDLALHQQQLEKAQKQFEKLGAVNLAASQEYEEVSGRYEELTHQMQDLENTVTQ 979 + A+ +Q+ +Y E Q++ +E+ + Sbjct: 244 LHKQAIAKHAVLEQE-------------------NKYVEAVNELRVYKSQLEQIESEILS 284 Query: 980 LKDAMKSIDQETRKLFMTTFDQVNHELQEL 1009 K+ + + Q + + Q + L Sbjct: 285 AKEEYQLVTQLFKNEILDKLRQTTDNIGLL 314
>FLGHOOKFLIK#Flagellar hook-length control protein signature. Length = 375 Score = 28.6 bits (63), Expect = 0.035 Identities = 20/83 (24%), Positives = 36/83 (43%) Query: 56 QLPIQTPEAQERKEPVLQDAAKMQEEKSIQIEVPEKAEVTSDAETTHPDVVPLDQLDSAE 115 QL + T + + EP++ D ++ ++ I V E V +D ++T + + A Sbjct: 49 QLLVATDKPTTKGEPLISDIVSDAQQANLLIPVDETPPVINDEQSTSTPLTTAQTMALAA 108 Query: 116 KLEKTAETDEKTKLSAPDATAKV 138 +K DEK D TA + Sbjct: 109 VADKNTTKDEKADDLNEDVTASL 131
>NUCEPIMERASE#Nucleotide sugar epimerase signature. Length = 334 Score = 54.4 bits (131), Expect = 2e-10 Identities = 41/187 (21%), Positives = 65/187 (34%), Gaps = 45/187 (24%) Query: 7 ILVTGATGYVAGWIIERLLNQGHTV-----HATVRDPSNTEKIKHLTDIAKKSEGSIHFF 61 LVTGA G++ + +RLL GH V D S +K + ++ F Sbjct: 3 YLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVS----LKQAR-LELLAQPGFQFH 57 Query: 62 KADL----LSEGVFDEAMQGCEIVIHTAS----PFVITN---YKDAVKDIIEPAVNGTAN 110 K DL +F E V + + + N Y D+ + G N Sbjct: 58 KIDLADREGMTDLFAS--GHFERVFISPHRLAVRYSLENPHAYADS-------NLTGFLN 108 Query: 111 VLESVNRTESVKRVVVTSSIAATYGDAIEIKATSNNEFDESCWNNTSNATH--QPYSYSK 168 +LE R ++ ++ SS ++ YG F + H Y+ +K Sbjct: 109 ILE-GCRHNKIQHLLYASS-SSVYG------LNRKMPFSTD-----DSVDHPVSLYAATK 155 Query: 169 VAAERKA 175 A E A Sbjct: 156 KANELMA 162
>HELNAPAPROT#Helicobacter neutrophil-activating protein A family signature. Length = 153 Score = 31.8 bits (72), Expect = 5e-04 Identities = 17/97 (17%), Positives = 34/97 (35%), Gaps = 14/97 (14%) Query: 46 HEMQEE-----ASHADALIRRVLFLEGKPNMNRDDIVTGEDV---------VSCLKADLA 91 HE EE A D + R+L + G+P + + ++A + Sbjct: 47 HEKFEELYDHAAETVDTIAERLLAIGGQPVATVKEYTEHASITDGGNETSASEMVQALVN 106 Query: 92 LEYHVRQKLADGVKLCEEKADYVSRDMLRAQMSDTEE 128 + + + L EE D + D+ + + E+ Sbjct: 107 DYKQISSESKFVIGLAEENQDNATADLFVGLIEEVEK 143
>PF06057#Type IV secretory pathway VirJ component Length = 243 Score = 29.8 bits (67), Expect = 0.015 Identities = 14/40 (35%), Positives = 20/40 (50%), Gaps = 12/40 (30%) Query: 180 VNVLELQNGH-FDRVVSVEMFEHVRNYQRLFEKIQNWLKP 218 V V+EL GH FD +Y ++ + I+ WLKP Sbjct: 214 VTVMELSGGHSFDD-----------DYDKVVKLIKGWLKP 242
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 86.4 bits (214), Expect = 8e-22 Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 1/126 (0%) Query: 6 ILIVEDHFELAATVCEFLETHGYVVDHARNLDAARTRLKSQPYHLLLLDINLPDGSGYSL 65 IL+ +D + + + L GY V N + + L++ D+ +PD + + L Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFDL 65 Query: 66 CDWLRVEQGLDLPVLMLTARDTVGDKLKGFSAGADDYLVKPFDFNELVARIRALIKRASG 125 ++ + DLPVL+++A++T +K GA DYL KPFD EL+ I + Sbjct: 66 LPRIK-KARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124 Query: 126 EVSNTQ 131 S + Sbjct: 125 RPSKLE 130
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 31.1 bits (70), Expect = 0.001 Identities = 14/61 (22%), Positives = 29/61 (47%), Gaps = 1/61 (1%) Query: 91 TVEHSVYIHKDYRGLGLSKHLMNELIKRAVESEVHVMVGCIDATNVASIQLHQKLGFIHS 150 +E + + KDYR G+ L+++ I+ A E+ ++ N+++ + K FI Sbjct: 91 LIED-IAVAKDYRKKGVGTALLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIG 149 Query: 151 G 151 Sbjct: 150 A 150
>PF03895#Serum resistance protein DsrA. Length = 79 Score = 38.3 bits (89), Expect = 6e-06 Identities = 15/76 (19%), Positives = 30/76 (39%), Gaps = 2/76 (2%) Query: 643 VEDKLSAGVASALALES--APYVAGKYTYAAGSGFYNGQSAIGVSLRKTADNGRWSLTGG 700 + +L G+A+ AL P GK + +A G Y ++A+ + + + + G Sbjct: 1 LSKELQTGLANQSALSMLVQPNGVGKTSVSAAVGGYRDKTALAIGVGSRITDRFTAKAGV 60 Query: 701 VAAASQGEASFRIGIN 716 G S+ + Sbjct: 61 AFNTYNGGMSYGASVG 76
>OMPADOMAIN#OMPA domain signature. Length = 346 Score = 118 bits (298), Expect = 2e-33 Identities = 53/154 (34%), Positives = 81/154 (52%), Gaps = 5/154 (3%) Query: 128 FNYPQPKPIVKTVTQPVIVKQKEQVDIINLSADALFKFNGSGLNDLLPRGHEELERLSND 187 + + Q + V + Q L +D LF FN + L P G L++L + Sbjct: 189 YRFGQGEA-APVVAPAPAPAPEVQTKHFTLKSDVLFNFNKA---TLKPEGQAALDQLYSQ 244 Query: 188 IRNHYIAVSRIHLVGHTDRIGSDSYNYNLGLKRAQTVKNYLVKDGIPAKTISFSSAGKSQ 247 + N + ++G+TDRIGSD+YN L +RAQ+V +YL+ GIPA IS G+S Sbjct: 245 LSNLDPKDGSVVVLGYTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESN 304 Query: 248 PI-SNGCFDISNMTSLKECLQVDRRVSVEITGVK 280 P+ N C ++ +L +CL DRRV +E+ G+K Sbjct: 305 PVTGNTCDNVKQRAALIDCLAPDRRVEIEVKGIK 338
>PF06340#Vibrio cholerae toxin co-regulated pilus biosynthesis protein F (TcpF) Length = 338 Score = 25.0 bits (54), Expect = 0.033 Identities = 13/47 (27%), Positives = 17/47 (36%), Gaps = 5/47 (10%) Query: 27 EDTHSSFVKI---ESTKVRSQANQYADDYVEKYYVDLYLKQQLQNQH 70 T S K E R A Y ++K Y+D YL Q + Sbjct: 84 SSTESDGAKTRTKEDFSARLLAGDYDS--LQKLYIDFYLAQTTFDWE 128
>BCTERIALGSPG#Bacterial general secretion pathway protein G signature. Length = 145 Score = 30.6 bits (69), Expect = 0.002 Identities = 10/25 (40%), Positives = 17/25 (68%) Query: 1 MKRHLGFTLIELLVSIAIFAILSAL 25 + GFTL+E++V I I +L++L Sbjct: 4 TDKQRGFTLLEIMVVIVIIGVLASL 28
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 33.4 bits (76), Expect = 1e-04 Identities = 23/80 (28%), Positives = 39/80 (48%), Gaps = 7/80 (8%) Query: 1 MKAKGFTLLEVMVALAIFATAAVALTKLGMQYTQSTANAILRTKAQFVAMNEASLMQINH 60 M+ +GFTLLE+M+ L + +A + + + S ++ +T A+F EA L + Sbjct: 1 MRQRGFTLLEMMLILLLMGVSAGMVL---LAFPASRDDSAAQTLARF----EAQLRFVQQ 53 Query: 61 EWLQGTQSKQVTSQGETWQI 80 LQ Q V+ + WQ Sbjct: 54 RGLQTGQFFGVSVHPDRWQF 73
>BCTERIALGSPH#Bacterial general secretion pathway protein H signature. Length = 170 Score = 50.7 bits (121), Expect = 2e-10 Identities = 20/99 (20%), Positives = 43/99 (43%), Gaps = 6/99 (6%) Query: 8 SQSGFTLVELMVVIVIVGILASLIFLNISGVDKRKAMQSRDFFLLDLQKINKESIDQGRV 67 Q GFTL+E+M++++++G+ A ++ L A Q+ F L+ + + + G+ Sbjct: 2 RQRGFTLLEMMLILLLMGVSAGMVLLAFPASRDDSAAQTLARFEAQLRFVQQRGLQTGQF 61 Query: 68 FALITHPETNVNPFGYELVEYFDQSQNAILDEKKKWQKY 106 F + HP+ ++ + + W Y Sbjct: 62 FGVSVHPD------RWQFLVLEARDGADPAPADDGWSGY 94
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 56.2 bits (135), Expect = 4e-12 Identities = 19/86 (22%), Positives = 39/86 (45%) Query: 1 MKMDRQAQFRAREALIFEVAEQLLLENGEAGMTLDALAAELDLAKGTLYKHFQSKDELYM 60 M + + + I +VA +L + G + +L +A + +G +Y HF+ K +L+ Sbjct: 1 MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFS 60 Query: 61 LLIVRNERMLLEMIQDKQKSFPEHLA 86 + +E + E+ + Q FP Sbjct: 61 EIWELSESNIGELELEYQAKFPGDPL 86
>PF06917#Periplasmic pectate lyase Length = 555 Score = 32.6 bits (74), Expect = 0.003 Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 13/94 (13%) Query: 204 YYDLLSEIDQHEY----QLNWLTKAPHFFSMDL---GKLTLEYTSPDYTSHFHSLEQNKR 256 YYDLL ID+ Q W + ++DL G + + +T + + Sbjct: 147 YYDLLVTIDRERTLNFLQGFWHAHVEDWKTLDLGRHGNYSKQRDPQVFTHPRYDVVNPAE 206 Query: 257 DQVIGSQSALYKGIELSFVNRIYDLLYQKSLYAP 290 + KG L+FVN DL+Y YA Sbjct: 207 LPKL----PETKG--LTFVNAGTDLIYAAYKYAE 234
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 43.1 bits (101), Expect = 3e-06 Identities = 19/73 (26%), Positives = 40/73 (54%), Gaps = 5/73 (6%) Query: 2 QLQQEITAKIHQVLQVEDVHIQPQDNLIEHGLHSLAIMQLVDHFEKRYSKALSYADFAMS 61 ++++I +LQ I Q++L++ GL S+ IM LV+ + +R +++ + A Sbjct: 234 NIRKQIAE----LLQETPEDITDQEDLLDRGLDSVRIMTLVEQW-RREGAEVTFVELAER 288 Query: 62 PTVQDWHDLIQAN 74 PT+++W L+ Sbjct: 289 PTIEEWQKLLTTR 301
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 251 bits (642), Expect = 4e-86 Identities = 110/252 (43%), Positives = 149/252 (59%), Gaps = 9/252 (3%) Query: 18 KIAWVTGVNQGIGAQIMQQLIAQNIYVVGFDLSIRNFMTSD--------HYEVHQCNVGD 69 KIA++TG QGIG + + L +Q ++ D + H E +V D Sbjct: 9 KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68 Query: 70 SSQVFDLCQKLL-NTSPPDYFINTAGVLHLDGHDALPIEAWRQTFEVNTFAPFYFLKNLS 128 S+ + ++ ++ P D +N AGVL +L E W TF VN+ F +++S Sbjct: 69 SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128 Query: 129 PHFRNKREGSIVMVSSNSARVPRIEMAAYGASKAALTSFSKTVALELAEYGVRVNIVSPG 188 + ++R GSIV V SN A VPR MAAY +SKAA F+K + LELAEY +R NIVSPG Sbjct: 129 KYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSPG 188 Query: 189 STVTPMLRQLWNDASGEQKTIHGNLAQYKVGIPLQKIALTQDIANAVMFLISDQASHITM 248 ST T M LW D +G ++ I G+L +K GIPL+K+A DIA+AV+FL+S QA HITM Sbjct: 189 STETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHITM 248 Query: 249 HDLVVDGGATLG 260 H+L VDGGATLG Sbjct: 249 HNLCVDGGATLG 260
>ISCHRISMTASE#Isochorismatase signature. Length = 312 Score = 278 bits (712), Expect = 7e-97 Identities = 98/200 (49%), Positives = 127/200 (63%) Query: 1 MTIPKIPSYPLPFKQDYPAAKVNWKIEKNRAALLIHDMQDYFVNFYGEDSELIQQVVDNI 60 M IP I Y +P D P KV+W + NRA LLIHDMQ+YFV+ + + + ++ NI Sbjct: 1 MAIPAIQPYQMPTASDMPQNKVSWVPDPNRAVLLIHDMQNYFVDAFTAGASPVTELSANI 60 Query: 61 AQIKAWCVANDVPVFYTAQPAEQKDQDRALLNDMWGPGLTAYPEQAAIVKKLMPNEQDQV 120 ++K CV +PV YTAQP Q DRALL D WGPGL + P + I+ +L P + D V Sbjct: 61 RKLKNQCVQLGIPVVYTAQPGSQNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLV 120 Query: 121 LTKWRYSAFYNSDLEKMLKDTQKDQLIICGVYAHIGVLQTAAEAFMNGIQPFVVGDSVAD 180 LTKWRYSAF ++L +M++ +DQLII G+YAHIG L TA EAFM I+ F VGD+VAD Sbjct: 121 LTKWRYSAFKRTNLLEMMRKEGRDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVAD 180 Query: 181 FSLKDHLFALQYVQNNLGVV 200 FSL+ H AL+Y Sbjct: 181 FSLEKHQMALEYAAGRCAFT 200
>PF05860#haemagglutination activity domain. Length = 117 Score = 65.2 bits (159), Expect = 1e-14 Identities = 21/144 (14%), Positives = 45/144 (31%), Gaps = 29/144 (20%) Query: 71 AQIQADNSANAGNRPVIGVGQNSQGQNVPVVNIQTPT-NGVSHNIYKQMDVLPEGVVLNN 129 AQI D + + N ++ T + + H+ +++ V G N Sbjct: 1 AQITPDTTLPIN-------SNITTEGNTRIIERGTQAGSNLFHS-FQEFSVPTSGTAFFN 52 Query: 130 SRTGANSSLVGTVGANPFLAKGEARIILNEVNSSVASRFEGNLEVAGQRADVIIANPAGI 189 + T I++ V S +G + A++ + NP GI Sbjct: 53 NPTNIQ-------------------NIISRVTGGSVSNIDGLIRANAT-ANLFLINPNGI 92 Query: 190 NIKGGGFINANKAILTTGKPQLNA 213 ++ + + + +L Sbjct: 93 IFGQNARLDIGGSFVGSTANRLKF 116
>ENTEROVIROMP#Enterobacterial virulence outer membrane protein signature. Length = 171 Score = 29.1 bits (65), Expect = 0.019 Identities = 27/123 (21%), Positives = 41/123 (33%), Gaps = 17/123 (13%) Query: 268 LRWVNWK-KFETRPNQFGAISEILTSE----ATGGEYTKGFKLDTYQKDQYSATIGLGQQ 322 + N K ++E + G I +E A+ G+Y K Y T G + Sbjct: 44 MGGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKN--------QYYGITAGPAYR 95 Query: 323 FTDKWSASTDISWDSG----TGHPASTLGPMKGSWSLGLGAQFNPAPNYFIAGGVKYFWL 378 D S + G T +P +S G G QFNP N + + + Sbjct: 96 INDWASIYGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRI 155 Query: 379 GDV 381 V Sbjct: 156 RSV 158
>SACTRNSFRASE#Streptothricin acetyltransferase signature. Length = 173 Score = 28.0 bits (62), Expect = 0.008 Identities = 21/121 (17%), Positives = 37/121 (30%), Gaps = 12/121 (9%) Query: 15 EIRTQLERLYDTSPEFGDGQDAIEQLEQNLAQYTTVYTAEFNTKIIGAIWC-TGQGESKI 73 + T E + P F +D + + + IG I + + Sbjct: 33 GVWTYTEERFS-KPYFKQYEDDDMDVSYVEEEGKAAFLYYLENNCIGRIKIRSNWNGYAL 91 Query: 74 LEYIVVHPANRGRGIAERLVS---EVCRMEEAKGVTMFE------PGCGAIHRCLAHIGK 124 +E I V R +G+ L+ E + G+ M E C + IG Sbjct: 92 IEDIAVAKDYRKKGVGTALLHKAIEWAKENHFCGL-MLETQDINISACHFYAKHHFIIGA 150 Query: 125 L 125 + Sbjct: 151 V 151
>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase signature. Length = 261 Score = 71.6 bits (175), Expect = 1e-16 Identities = 55/193 (28%), Positives = 86/193 (44%), Gaps = 2/193 (1%) Query: 2 KNFKNKVAAITGAGSGIGQQLAVLLAKEGCHLSLSDVNEQGLVATVELLKPYQIRVTTKK 61 K + K+A ITGA GIG+ +A LA +G H++ D N + L V LK Sbjct: 4 KGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFP 63 Query: 62 VDVSDRQAIKVWAAETVQNHGSVNMIFNNAGVALGSTVEGESYEDLEWVMGINFWGVVYG 121 DV D AI A + G ++++ N AGV + S E+ E +N GV Sbjct: 64 ADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNA 123 Query: 122 TKEFLPLIKQSKEGHIINISSLFGLTAQPTQSAYNASKFAVRGFTESLRQELDMEKSGVS 181 ++ + + G I+ + S + + +AY +SK A FT+ L EL + + Sbjct: 124 SRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLEL--AEYNIR 181 Query: 182 ALCVHPGGIRTNI 194 V PG T++ Sbjct: 182 CNIVSPGSTETDM 194
>HTHTETR#TetR bacterial regulatory protein HTH signature. Length = 215 Score = 61.2 bits (148), Expect = 1e-13 Identities = 25/176 (14%), Positives = 58/176 (32%), Gaps = 7/176 (3%) Query: 29 SERKYARREKLIEAGIETYGTQGFFSVTVKDVCNEAKLTERYFYESFKKSEDLFQTIFLK 88 + R+ +++ + + QG S ++ ++ A +T Y FK DLF I+ Sbjct: 6 KQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVTRGAIYWHFKDKSDLFSEIWEL 65 Query: 89 QIEILQNNVMQAVMQHTPSPEKMIKAGLTALLHTLKDDPRLARIIYIDAMLVQELHNQAT 148 + ++ + P +++ L +L + + R ++ I E + Sbjct: 66 SESNIGELELEYQAKFPGDPLSVLREILIHVLESTVTEERRRLLMEIIFHK-CEFVGEMA 124 Query: 149 IHETMMR--FDRMIQAFVMLASPHIRYSE----QELSLVASGLNGYVTQIAIRWVM 198 + + R I A + GY++ + W+ Sbjct: 125 VVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMTRRAAIIMRGYISGLMENWLF 180
>HTHFIS#FIS bacterial regulatory protein HTH signature. Length = 484 Score = 81.8 bits (202), Expect = 4e-20 Identities = 32/123 (26%), Positives = 60/123 (48%), Gaps = 3/123 (2%) Query: 6 ILIVDDELPIREMIHTSLDMAGFQCLQAEDAKQAHQMIVDQRPALILLDWMLPGGVSGVD 65 IL+ DD+ IR +++ +L AG+ +A + I L++ D ++P + D Sbjct: 6 ILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDE-NAFD 64 Query: 66 LCRRLKRDENLSEIPVIMLTARGEEDHKVQGLDAGADDYMTKPFSTRELVSRIKAVLRRA 125 L R+K+ ++PV++++A+ ++ + GA DY+ KPF EL+ I L Sbjct: 65 LLPRIKKAR--PDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEP 122 Query: 126 NAL 128 Sbjct: 123 KRR 125
>PF06580#Sensor histidine kinase Length = 349 Score = 29.1 bits (65), Expect = 0.040 Identities = 11/38 (28%), Positives = 17/38 (44%), Gaps = 4/38 (10%) Query: 349 LITNAIKY----TPKGGIITIGWHDDGVHGYFTVQDNG 382 L+ N IK+ P+GG I + D V++ G Sbjct: 263 LVENGIKHGIAQLPQGGKILLKGTKDNGTVTLEVENTG 300