PredictBias

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 27.9 bits (62), Expect = 0.037

		 Identities = 13/80 (16%), Positives = 25/80 (31%), Gaps = 16/80 (20%)

		

		Query: 102 GAYALPQTFAEALKLAAQQAERLELQQAELKKQAPKVAYYEEVLQSESTYNTNQIAKELG 161

		            ++      +        + E   +  A L                    N  + A  LG

		Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAA-LTATR---------------GNQIKAADLLG 460

		

		Query: 162 MSAITLNKKLQDLKVQYRQG 181

		           ++  TL KK+++L V   + 

		Sbjct: 461 LNRNTLRKKIRELGVSVYRS 480

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 24.1 bits (52), Expect = 0.038

		 Identities = 8/26 (30%), Positives = 18/26 (69%)

		

		Query: 34  YDDDKKEKEIDLTEQTPEDLEKMLEK 59

		           +  D+K ++++LTE+    +E++L K

		Sbjct: 263 FSVDEKSRQVNLTERGLVLIEELLVK 288

		

		

		>PF07675#Cleaved Adhesin

		          Length = 1358

		

		 Score = 30.8 bits (69), Expect = 0.005

		 Identities = 12/16 (75%), Positives = 12/16 (75%)

		

		Query: 83  PNPTPNPNPEPKPNEG 98

		           PN TPNPNP P PN G

		Sbjct: 614 PNGTPNPNPNPNPNPG 629

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 30.7 bits (69), Expect = 0.002

		 Identities = 9/29 (31%), Positives = 16/29 (55%)

		

		Query: 36  LFEITEGTLNNWKNEHPEFLESIKKGKEE 64

		           LF+    T+ N++N  P+F+  +KK    

		Sbjct: 336 LFDQKGNTIRNFQNIFPKFVSDVKKELSH 364

		

		

		>FLGMOTORFLIG#Flagellar motor switch protein FliG signature.

		          Length = 344

		

		 Score = 34.0 bits (78), Expect = 0.001

		 Identities = 26/106 (24%), Positives = 43/106 (40%), Gaps = 9/106 (8%)

		

		Query: 9   ELIKNLIKEKNAKEVALMLSEMEAPDIASIFEDLEEEEQHFLYDLMSNEK--SAEVLLEI 66

		             I N I++++ + +AL+LS ++    + I   L  E Q  +   ++     S EV+ E+

		Sbjct: 126 ANILNFIQQEHPQTIALILSYLDPQKASFILSSLPTEVQTNVARRIALMDRTSPEVVREV 185

		

		Query: 67  DEDERKSFMKGLSSQ-------EIADEIINEIDSDDAADIISELPE 105

		           +    K      S         +   EIIN  D      II  L E

		Sbjct: 186 ERVLEKKLASLSSEDYTSAGGVDNVVEIINMADRKTEKFIIESLEE 231

		

		

		>ISCHRISMTASE#Isochorismatase signature.

		          Length = 312

		

		 Score = 35.8 bits (82), Expect = 5e-05

		 Identities = 39/161 (24%), Positives = 66/161 (40%), Gaps = 19/161 (11%)

		

		Query: 5   EKNPALVLI-DVQKAFLEEDYWGGNRNNKNAEEICGKI--LKKW-RELNLPIFHIRH-SS 59

		           + N A++LI D+Q  F+  D +          E+   I  LK    +L +P+ +     S

		Sbjct: 27  DPNRAVLLIHDMQNYFV--DAFTAG--ASPVTELSANIRKLKNQCVQLGIPVVYTAQPGS 82

		

		Query: 60  DNPKSKLHIT-------NAGFEFSEYV---IPNDSETIITKNVNSAFIGTTLKEQIDSLN 109

		            NP  +  +T       N+G    + +    P D + ++TK   SAF  T L E +    

		Sbjct: 83  QNPDDRALLTDFWGPGLNSGPYEEKIITELAPEDDDLVLTKWRYSAFKRTNLLEMMRKEG 142

		

		Query: 110 INTLVIVGITTNHCVSTTTRMSGNYGYETYLISDATATFDR 150

		            + L+I GI  +     T   +     + + + DA A F  

		Sbjct: 143 RDQLIITGIYAHIGCLVTACEAFMEDIKAFFVGDAVADFSL 183

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 29.4 bits (66), Expect = 0.006

		 Identities = 12/51 (23%), Positives = 21/51 (41%), Gaps = 3/51 (5%)

		

		Query: 6   PYNGNVTSINPEDIESTVILKDATATAIYGARGANGVVLINTKTGRGRSVI 56

		            Y  N  +++   +   V L +A A  +   RGA  +V    K   G  ++

		Sbjct: 752 EYRENRVALDTNTLADNVDLDNAVANVVPT-RGA--IVRAEFKARVGIKLL 799

		

		

		>LPSBIOSNTHSS#Lipopolysaccharide core biosynthesis protein

		          signature.

		          Length = 166

		

		 Score = 25.9 bits (57), Expect = 0.019

		 Identities = 11/37 (29%), Positives = 19/37 (51%), Gaps = 2/37 (5%)

		

		Query: 56 KDRQIPDEVIVGGYEALNPKKRPLFYRDKALEYIKQL 92

		          +  ++ D+V V      NP K+P+F   + LE I + 

		Sbjct: 22 RGCRLFDQVYVA--VLRNPNKQPMFSVQERLEQIAKA 56

		

		

		>STREPTOPAIN#Streptopain (C10) cysteine protease family signature.

		          Length = 398

		

		 Score = 29.3 bits (65), Expect = 0.017

		 Identities = 18/72 (25%), Positives = 37/72 (51%), Gaps = 7/72 (9%)

		

		Query: 186 IEGYIKNIREDGKIDVSLQPEGYTNIDEFKQKILDKLDENYGLLYLSDQSSPEEIKTELQ 245

		           +E Y++ I+E+ K+D +     Y    E KQ ++  L ++ G+ Y  +Q +P  + T + 

		Sbjct: 121 MESYVEQIKENKKLDTT-----YAGTAEIKQPVVKSLLDSKGIHY--NQGNPYNLLTPVI 173

		

		Query: 246 MSKKNFKKAIGG 257

		              K  +++  G

		Sbjct: 174 EKVKPGEQSFVG 185

		

		

		>TCRTETOQM#Tetracycline resistance protein TetO/TetQ/TetM family

		           signature.

		          Length = 639

		

		 Score =  178 bits (452), Expect = 2e-50

		 Identities = 100/448 (22%), Positives = 178/448 (39%), Gaps = 89/448 (19%)

		

		Query: 3   NIRNIAIIAHVDHGKTTLVDKIIHATNIFRE--NQESGELIMDNNDLERERGITILSKNI 60

		            I NI ++AHVD GKTTL + +++ +    E  + + G    DN  LER+RGITI +   

		Sbjct: 2   KIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGIT 61

		

		Query: 61  SVTYKDTKINVIDTPGHADFGGEVERVLKMADGVLLLVDAFEGPMPQTRFVLHKALELGL 120

		           S  +++TK+N+IDTPGH DF  EV R L + DG +LL+ A +G   QTR + H   ++G+

		Sbjct: 62  SFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGI 121

		

		Query: 121 KPIVVINKVDKPNCRPDEVHDQVFD-------------LFFNLDATEEQLD--------- 158

		             I  INK+D+       V+  + +             L+ N+  T              

		Sbjct: 122 PTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVELYPNMCVTNFTESEQWDTVIEG 181

		

		Query: 159 --------------------------------FPTFYGSSKESWFNSSLEKSENILPLLD 186

		                                           FP ++GS+K          +  I  L++

		Sbjct: 182 NDDLLEKYMSGKSLEALELEQEESIRFHNCSLFPVYHGSAK---------NNIGIDNLIE 232

		

		Query: 187 GILQYVPEPKVEEGN-LQMQVTSLDYSSFLGRIAVGKIIRGSVKESQWIGLAQEDGKIVK 245

		            I            + L  +V  ++YS    R+A  ++  G +     + +++++    K

		Sbjct: 233 VITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKE----K 288

		

		Query: 246 GKVKELYIFEGLGKKKVSEVFAGDICAIVGFDNFQIGDTFVDLENPEPLPRLSIDEPTLN 305

		            K+ E+Y        K+ + ++G+I  +   +  ++     D +      R+    P L 

		Sbjct: 289 IKITEMYTSINGELCKIDKAYSGEIVILQN-EFLKLNSVLGDTKLLPQRERIENPLPLLQ 347

		

		Query: 306 MTFSINNSPFFGKDGKYVTSNHLKERLEKEL----EKNLALRVQQTEDANTFLVFGRGIL 361

		            T   +                 +E L   L    + +  LR       +  ++   G +

		Sbjct: 348 TTVEPSKP-------------QQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKV 394

		

		Query: 362 HLSVLIETMRRE-GYEMTIGQPQVILKE 388

		            + V    ++ +   E+ I +P VI  E

		Sbjct: 395 QMEVTCALLQEKYHVEIEIKEPTVIYME 422

		

		

		

		 Score = 53.3 bits (128), Expect = 2e-09

		 Identities = 25/93 (26%), Positives = 39/93 (41%)

		

		Query: 386 LKEIDGEQCEPYESLVVDVPEEYASRVIDLATQRKGDLHIMETKGEMQHLEFEIPSRGLI 445

		           LK+   E  EPY S  +  P+EY SR    A +   ++   + K     L  EIP+R + 

		Sbjct: 528 LKKAGTELLEPYLSFKIYAPQEYLSRAYTDAPKYCANIVDTQLKNNEVILSGEIPARCIQ 587

		

		Query: 446 GLRSQMLTATAGEAIMAHRFVDYKPFKGQIPGR 478

		             RS +   T G ++       Y    G+   +

		Sbjct: 588 EYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQ 620

		

		

		>PF05844#YopD protein

		          Length = 295

		

		 Score = 27.7 bits (61), Expect = 0.047

		 Identities = 19/108 (17%), Positives = 32/108 (29%), Gaps = 9/108 (8%)

		

		Query: 150 ADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQEAFEMGMVNKVVPHEELEDTAYE 209

		           A  ++  G  G+    K + Q+K  +    GRN       +M  + K    E+ +     

		Sbjct: 131 ALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDA--KMQALGKTS-DEDRKIVGKV 187

		

		Query: 210 WAQEILAKSPTSIRM-LKFAMNLTDDGMVGQQVFAGEATRLAYMTDEA 256

		           WA +    S         F            QV          M + +

		Sbjct: 188 WAADQAQDSVALRAAGRAFESR-----NGALQVANTVIQSFVQMANAS 230

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score = 33.0 bits (75), Expect = 8e-04

		 Identities = 38/212 (17%), Positives = 69/212 (32%), Gaps = 34/212 (16%)

		

		Query: 29  QTLFVMVLALLSNTITAQTREIINPKGRWFFGAEVGLNS-------KMSVPPSKMSFMQG 81

		           +T   + +AL      AQ     N    W+ GA++G +          + P  +     G

		Sbjct: 3   KTAIAIAVALAGFATVAQAAPKDNT---WYTGAKLGWSQYHDTGFINNNGPTHENQLGAG 59

		

		Query: 82  GFLAEYFFAKNWSVSGRLKYFETGVINPMSDGSKGFFE--GAVISVPLNIVWRYRIVENF 139

		            F   Y           + Y   G +        G ++  G  ++  L     Y I ++ 

		Sbjct: 60  AFGG-YQVNPYVGF--EMGYDWLGRMPYKGSVENGAYKAQGVQLTAKL----GYPITDDL 112

		

		Query: 140 SGNLNLGLAINQEVKSNYHYQPNEATDYDKLYASFNAGIGCSYFISKYMALYMNYEAIVL 199

		                LG  +    +++     N          S     G  Y I+  +A  + Y     

		Sbjct: 113 DIYTRLGGMV---WRADTKS--NVYGKNHDTGVSPVFAGGVEYAITPEIATRLEY----- 162

		

		Query: 200 GNDRDESDF--LEILPNSPNNSLLSIGVKYSF 229

		              +  ++      +   P+N +LS+GV Y F

		Sbjct: 163 ---QWTNNIGDAHTIGTRPDNGMLSLGVSYRF 191

		

		

		>PF00577#Outer membrane usher protein FimD

		          Length = 878

		

		 Score = 31.0 bits (70), Expect = 0.007

		 Identities = 13/72 (18%), Positives = 23/72 (31%), Gaps = 10/72 (13%)

		

		Query: 163 VYLRF----GRPAVPVFMPEDMPFEIGKGILLQEGKDVTIVATGHLVW-ESLVAAEQL-- 215

		           V   F    G   +      + P   G  +  +  +   IVA    V+   +  A ++  

		Sbjct: 786 VRAEFKARVGIKLLMTLTHNNKPLPFGAMVTSESSQSSGIVADNGQVYLSGMPLAGKVQV 845

		

		Query: 216 ---EKEGISCEV 224

		              E+E   C  

		Sbjct: 846 KWGEEENAHCVA 857

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 83.7 bits (207), Expect = 2e-20

		 Identities = 68/336 (20%), Positives = 118/336 (35%), Gaps = 57/336 (16%)

		

		Query: 7   KILITGALGQIGTELTAKLVE----IYGKDNVIASGID-----KWREGITTAG-HYERID 56

		           K L+TGA G IG  ++ +L+E    + G DN +    D        E +   G  + +ID

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDN-LNDYYDVSLKQARLELLAQPGFQFHKID 60

		

		Query: 57  VTNFKLLEDFIKENKITTVYHLASLLSGT--SEKQPLFAWKLNLEPLLHLCELAKEGYLK 114

		           + + + + D         V+           S + P      NL   L++ E  +   ++

		Sbjct: 61  LADREGMTDLFASGHFERVFISPHR-LAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQ 119

		

		Query: 115 KIFWPSSIAVFGKGIPKHNVGQDVVLNPTTVYGISKMAGEKWCEYYHDKYGVDVRSIRY- 173

		            + + SS +V+G          D V +P ++Y  +K A E     Y   YG+    +R+ 

		Sbjct: 120 HLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFF 179

		

		Query: 174 ----PGLISWKAPAGGGTTDYAVEIFYEAVEKGE-YQCFISENTAMPMLYMDDAINATIK 228

		               P    W  P      D A+  F +A+ +G+    +          Y+DD   A I+

		Sbjct: 180 TVYGP----WGRP------DMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIR 229

		

		Query: 229 LMQEPAENISVWGS--------------YNLGGMSFTP-AELTNEI-----KKVMPNFKI 268

		           L        + W                YN+G  S     +    +      +   N   

		Sbjct: 230 LQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP 289

		

		Query: 269 SYQPDFRQSIADSWPASIDDSKAKEDWGLSYEFDIK 304

		               D  ++ AD+           E  G + E  +K

		Sbjct: 290 LQPGDVLETSADT-------KALYEVIGFTPETTVK 318

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 31.3 bits (71), Expect = 0.007

		 Identities = 7/40 (17%), Positives = 21/40 (52%)

		

		Query: 24  LVQDGDYVEKDQPIAEVDSDKATLELPAEESGIITLKAEE 63

		           +V++G+ V K   + ++ +  A  +    +S ++  + E+

		Sbjct: 111 IVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQ 150

		

		

		

		 Score = 31.0 bits (70), Expect = 0.010

		 Identities = 27/184 (14%), Positives = 64/184 (34%), Gaps = 19/184 (10%)

		

		Query: 53  ESGIIT-LKAEEGDVVEVGQVVCLIDMSAAKPEGGAAKQ--ETAKVEENK--------EE 101

		           E+ I+  +  +EG+ V  G V+  +    A+ +    +     A++E+ +        E 

		Sbjct: 103 ENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIEL 162

		

		Query: 102 VKAEAPKQEASPATYATGTPSPAAKKILDEKGVEASQVKGTGRDGRITKEDAEQASVPAM 161

		            K    K    P               L ++     Q +   ++  + K+ AE+ +V A 

		Sbjct: 163 NKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLA- 221

		

		Query: 162 GSVFATNGSRSSKTTKLSSLRRKLAQRLVS------VKNETAMLTTFNEVDMSEIFRIRK 215

		             +         + ++L      L ++ ++       +N+         V  S++ +I  

		Sbjct: 222 -RINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNELRVYKSQLEQIES 280

		

		Query: 216 QYKE 219

		           +   

		Sbjct: 281 EILS 284

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 29.1 bits (65), Expect = 0.046

		 Identities = 19/109 (17%), Positives = 36/109 (33%), Gaps = 13/109 (11%)

		

		Query: 201 IEEENYEIIKNAFDFTDHSAKQ---IMVPRQNILSID---------IETSIDEIIE-IIM 247

		           +E  N++I K   ++ D +  Q   I   R  +L +           E      I+  I 

		Sbjct: 634 VESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIREDVFKATIDAYIP 693

		

		Query: 248 ESGYSRIPVYEGSIDNVIGIFYTKEIIRNYIKTKGQLTHEDLRGFLREA 296

		                 +    G  + +   F     I  ++  + +L  E LR  +   

		Sbjct: 694 PQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERILAQ 742

		

		

		>TYPE4SSCAGA#Type IV secretion system CagA exotoxin signature.

		          Length = 1147

		

		 Score = 32.4 bits (73), Expect = 0.008

		 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 6/118 (5%)

		

		Query: 432 NDNYSRSKNDLDSIRRKIRA-----AEKDAED-EYIANLRNEKTRLDNRVYSIDKEVYDL 485

		           N N   +K   +S + +I A     A +DA    Y  NL+  K  L +++ +++K + D 

		Sbjct: 638 NKNKMEAKAQANSQKDEIFALINKEANRDARAIAYAQNLKGIKRELSDKLENVNKNLKDF 697

		

		Query: 486 SEKIGSFKNEIKTLKQRQEELRKKIDDSRRYSDKDKITQRQIENLRNFIKDFKDATKK 543

		            +    FKN       + EE  K +  S +    +     ++ENL   + +FK+   K

		Sbjct: 698 DKSFDEFKNGKNKDFSKAEETLKALKGSVKDLGINPEWISKVENLNAALNEFKNGKNK 755

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  193 bits (492), Expect = 4e-61

		 Identities = 83/360 (23%), Positives = 154/360 (42%), Gaps = 51/360 (14%)

		

		Query: 1   MKSIIITGGAGFIGSHVVREFVKNLPNTKIINLDALT--YAGNLENLK-DIENEPNYTFE 57

		           MK  ++TG AGFIG HV +  ++     +++ +D L   Y  +L+  + ++  +P + F 

		Sbjct: 1   MK-YLVTGAAGFIGFHVSKRLLEA--GHQVVGIDNLNDYYDVSLKQARLELLAQPGFQFH 57

		

		Query: 58  RADITKVEELRKVFEKHQPDAVVHLAAESHVDRSITDPNAFINTNVMGTANLLNLCREFW 117

		           + D+   E +  +F     + V        V  S+ +P+A+ ++N+ G  N+L  CR   

		Sbjct: 58  KIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHN- 116

		

		Query: 118 TLNPEHTHGNFPDEPRQNLFYHVSTDEVYGALGETGFFTEETPYD-PKSPYSASKAASDH 176

		               +H            L Y  S+  VYG L     F+ +   D P S Y+A+K A++ 

		Sbjct: 117 --KIQH------------LLY-ASSSSVYG-LNRKMPFSTDDSVDHPVSLYAATKKANEL 160

		

		Query: 177 LVRAYGNTYGMPFIVSNCSNNYGPNHFPEKLIPLCISNIINEKPLPIYGDGKYTRDWLFV 236

		           +   Y + YG+P         YGP   P+  +      ++  K + +Y  GK  RD+ ++

		Sbjct: 161 MAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYI 220

		

		Query: 237 IDHAKAIFQIFHEAKT------------------GETYNIGGWNEWQNIDLIKELIKQMD 278

		            D A+AI ++                           YNIG       ++L  + I+ ++

		Sbjct: 221 DDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGN---SSPVEL-MDYIQALE 276

		

		Query: 279 AKLGRPEGYSEKLITFVKDRPGHDKRYAIDATKLNKDLGWKPSVTFEEGLAKTIDWFLNN 338

		             LG      E     +  +PG     + D   L + +G+ P  T ++G+   ++W+ + 

		Sbjct: 277 DALGI-----EAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYRDF 331

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  116 bits (291), Expect = 1e-33

		 Identities = 81/249 (32%), Positives = 118/249 (47%), Gaps = 10/249 (4%)

		

		Query: 4   KKILIVGASSGIGKATAITLASQGFQLVLMSRNVEKLTEVSQQCSGDGH--QVFSVDVTD 61

		           K   I GA+ GIG+A A TLASQG  +  +  N EKL +V      +    + F  DV D

		Sbjct: 9   KIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPADVRD 68

		

		Query: 62  EEALYNAIAESLQDGIPYDGFVYSAGMEATIPSKLIKKEYLERVLSVNSIPAVLISKCLL 121

		             A+    A   ++  P D  V  AG+        +  E  E   SVNS      S+ + 

		Sbjct: 69  SAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASRSVS 128

		

		Query: 122 KKNYLSSQGASFVLVSSVMGHLGQTAKTAYCMSKHALSGISKALSLELAPKNIRVNCVLP 181

		           K   +  +  S V V S    + +T+  AY  SK A    +K L LELA  NIR N V P

		Sbjct: 129 KY-MMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIVSP 187

		

		Query: 182 GMVKTDMSIKIL------ESISQENIQKIESMHPLG-LGQPEDVANTIKFLLSEDSKWIT 234

		           G  +TDM   +       E + + +++  ++  PL  L +P D+A+ + FL+S  +  IT

		Sbjct: 188 GSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGHIT 247

		

		Query: 235 GVDIPVDGG 243

		             ++ VDGG

		Sbjct: 248 MHNLCVDGG 256

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 45.2 bits (107), Expect = 8e-07

		 Identities = 39/159 (24%), Positives = 66/159 (41%), Gaps = 35/159 (22%)

		

		Query: 169 LAAEGKLDPVIGRDEEIRRVLQILSR--RTKNNPILIGEPGVGKTAIAEGIAHR------ 220

		                   P++GR   ++ + ++L+R  +T    ++ GE G GK  +A  + H       

		Sbjct: 130 EDDSQDGMPLVGRSAAMQEIYRVLARLMQTDLTLMITGESGTGKELVARAL-HDYGKRRN 188

		

		Query: 221 -----IISGDVPENLMDKTLYSLDMGALV-AGAKYKGEFEERLKSVVNEVTKSDGQIILF 274

		                I    +P +L++  L+  + GA   A  +  G FE+           ++G   LF

		Sbjct: 189 GPFVAINMAAIPRDLIESELFGHEKGAFTGAQTRSTGRFEQ-----------AEGG-TLF 236

		

		Query: 275 IDEIHTLVGAGGGEGAMDAANILKPALARGELRAIGATT 313

		           +DEI        G+  MDA   L   L +GE   +G  T

		Sbjct: 237 LDEI--------GDMPMDAQTRLLRVLQQGEYTTVGGRT 267

		

		

		

		 Score = 40.6 bits (95), Expect = 2e-05

		 Identities = 37/182 (20%), Positives = 64/182 (35%), Gaps = 30/182 (16%)

		

		Query: 546 KLLQSEREKLLHLEDELHKR--VVGQEEAIEAVANAIRRNRAGLNDEKKPIGSFLFLGTT 603

		           + L   + +   LED+      +VG+  A++ +   + R    L      +   +  G +

		Sbjct: 117 RALAEPKRRPSKLEDDSQDGMPLVGRSAAMQEIYRVLAR----LMQTDLTL---MITGES 169

		

		Query: 604 GVGKTELAKALAEFLFDDENNMTRIDMSEYQERHSVSRLVGAPPGYVGYDEGGQLTEAVR 663

		           G GK  +A+AL ++          I+M+        S L G         E G  T A  

		Sbjct: 170 GTGKELVARALHDYGKRRNGPFVAINMAAIPRDLIESELFGH--------EKGAFTGAQT 221

		

		Query: 664 RRPYSV-------VLLDEIEKAHPDVFNTLLQVLDDG---RLTDNKGRVVNFKNTIVIMT 713

		           R            + LDEI     D    LL+VL  G    +        + +   ++  

		Sbjct: 222 RSTGRFEQAEGGTLFLDEIGDMPMDAQTRLLRVLQQGEYTTVGGRTPIRSDVR---IVAA 278

		

		Query: 714 SN 715

		           +N

		Sbjct: 279 TN 280

		

		

		>SUBTILISIN#Subtilisin serine protease family (S8) signature.

		          Length = 326

		

		 Score = 80.7 bits (199), Expect = 2e-18

		 Identities = 62/325 (19%), Positives = 98/325 (30%), Gaps = 77/325 (23%)

		

		Query: 119 GQGMTAYVWDAGSVRPSHREFGNRVTVGDGASHNGDN----------HATHVGGTIAATG 168

		           G+G+   V D G     H +   R+  G   + + +           H THV GTIAAT 

		Sbjct: 40  GRGVKVAVLDTG-CDADHPDLKARIIGGRNFTDDDEGDPEIFKDYNGHGTHVAGTIAATE 98

		

		Query: 169 VTAAAKGMASKALIRSYD--WSSDYSEASTAARAGMLLSNHSYGYNSLSLPDWYFGAYIG 226

		                 G+A +A +            +     +             S+SL         G

		Sbjct: 99  NENGVVGVAPEADLLIIKVLNKQGSGQYDWIIQGIYYAIEQKVDIISMSL---------G 149

		

		Query: 227 ESADWDRLMYSAPY-----YLMCVAAGNDGSNYGYNQDTGKYELLNASPLGGTTNDYDKL 281

		              D   L  +         L+  AAGN+G                   LG         

		Sbjct: 150 GPEDVPELHEAVKKAVASQILVMCAAGNEGDGDD-----------RTDELGYP------- 191

		

		Query: 282 TGHSTSKNALVVANANDANVDAQGNLLSVTIASSSSQGPTDDLRVKPDIAGNGVQVYSPV 341

		                    + V   N               +  S+         + D+   G  + S  

		Sbjct: 192 ---GCYNEVISVGAINFDR----------HASEFSNSNN------EVDLVAPGEDILS-- 230

		

		Query: 342 AYTSTSTGKTYGNAYYDSYTGTSMASPNVTGSLLLVQQHYNNKEGQFMLGAQLKGLALHT 401

		                    T     Y +++GTSMA+P+V G+L L++Q  N    + +   +L    +  

		Sbjct: 231 ---------TVPGGKYATFSGTSMATPHVAGALALIKQLANASFERDLTEPELYAQLIKR 281

		

		Query: 402 ADDAGMEGPDANFGWGLLNVKKMVE 426

		               G        G GLL +  + E

		Sbjct: 282 TIPLG--NSPKMEGNGLLYLTAVEE 304

		

		

		>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD

		           chaperone signature.

		          Length = 168

		

		 Score = 29.1 bits (65), Expect = 0.031

		 Identities = 8/91 (8%), Positives = 26/91 (28%)

		

		Query: 414 IEALKKTMAADPKNTDNIYKLAMAYQEAKNWNGAAYTWQNMIDLIPDWAPAYYSQGYAYQ 473

		            +  +     D  ++     L    Q    ++ A +++     +        +       

		Sbjct: 56  HKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPRFPFHAAECLL 115

		

		Query: 474 QAGNNELAKVSYQTYIDNMNKKPAEEQMQGK 504

		           Q G    A+       + +  K   +++  +

		Sbjct: 116 QKGELAEAESGLFLAQELIADKTEFKELSTR 146

		

		

		>PF03544#Gram-negative bacterial tonB protein

		          Length = 243

		

		 Score = 41.9 bits (98), Expect = 1e-06

		 Identities = 38/190 (20%), Positives = 62/190 (32%), Gaps = 11/190 (5%)

		

		Query: 86  ILEQPKEETPPPPPPPKVEEEKIEIIQNVVPEPVKAPTVETPPPPISKQLETTTGLVNQE 145

		           ++     E P    PP     + E     +PEP K   V    P    +       V + 

		Sbjct: 54  MVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPK--PKPKPVKKV 111

		

		Query: 146 GVKKPSYAPPPPPPSTGKGTTVEVKPQVSTTEVYTTVDQEAEFSGGGINGFRSAFQESFD 205

		              K    P    P++    T   +P  ST        +       G         +   

		Sbjct: 112 EQPKRDVKPVESRPASPFENTAPARPTSSTAT--AATSKPVTSVASGPRALSRNQPQYPA 169

		

		Query: 206 TSVMEGDEGTLKAEVTFVVERDGSLSQVKVTGS--NSTFNREAERAVKSIKKKWTPGKVN 263

		            +     EG +K  V F V  DG +  V++  +   + F RE + A++    ++ PGK  

		Sbjct: 170 RAQALRIEGQVK--VKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRR--WRYEPGKPG 225

		

		Query: 264 GE-PVRSRFR 272

		               V   F+

		Sbjct: 226 SGIVVNILFK 235

		

		

		>V8PROTEASE#V8 serine protease family signature.

		          Length = 336

		

		 Score = 67.3 bits (164), Expect = 2e-14

		 Identities = 32/167 (19%), Positives = 57/167 (34%), Gaps = 32/167 (19%)

		

		Query: 120 PTGLGSGVIISPDGYIISNNHVVAGASKLEVTLS------------NKKTYVAKLIGSDP 167

		            T + SGV++  D  +++N HVV         L             N      ++     

		Sbjct: 100 GTFIASGVVVGKD-TLLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSG 158

		

		Query: 168 STDIALLKIED--------SGLPYLNFANSDLLEVGQWVVAVGNPLGLNSTVTAGIVSAK 219

		             D+A++K             +     +N+   +V Q +   G P        A +  +K

		Sbjct: 159 EGDLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYPGDKPV---ATMWESK 215

		

		Query: 220 GRSIDLLRQQSKTPIESFIQTDAVINRGNSGGALVNLSGDLVGINSA 266

		           G+   L            +Q D     GNSG  + N   +++GI+  

		Sbjct: 216 GKITYL--------KGEAMQYDLSTTGGNSGSPVFNEKNEVIGIHWG 254

		

		

		>TYPE3IMSPROT#Type III secretion system inner membrane S protein

		           family signature.

		          Length = 354

		

		 Score = 30.1 bits (68), Expect = 0.007

		 Identities = 23/121 (19%), Positives = 52/121 (42%), Gaps = 5/121 (4%)

		

		Query: 94  ILLIGVFSWVLVYCISILIYYGK-ANFDFEYIKKYFIYFVLFQFFLSLFAYYLMSIKPSV 152

		            +L+G+  +   +   +++   + +   F     Y +  VL +FF   F    ++   ++

		Sbjct: 40  AMLMGLSDYYFEHFSKLMLIPAEQSYLPFSQALSYVVDNVLLEFFYLCFPLLTVAALMAI 99

		

		Query: 153 WTVFISIGYLFFEDTIVMMNKDTIGNYLPKESFVRLFTENSILTISVSLAYISILLLLIY 212

		            +  +  G+L   + I    K  I    P E   R+F+  S++    S+  + +L +LI+

		Sbjct: 100 ASHVVQYGFLISGEAI----KPDIKKINPIEGAKRIFSIKSLVEFLKSILKVVLLSILIW 155

		

		Query: 213 K 213

		            

		Sbjct: 156 I 156

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 27.6 bits (61), Expect = 0.006

		 Identities = 9/33 (27%), Positives = 20/33 (60%)

		

		Query: 37  LIISFVNIFPKFEGRGLGKALIREAISFAREHQ 69

		            +I  + +   +  +G+G AL+ +AI +A+E+ 

		Sbjct: 90  ALIEDIAVAKDYRKKGVGTALLHKAIEWAKENH 122

		

		

		>OMPADOMAIN#OMPA domain signature.

		          Length = 346

		

		 Score = 35.7 bits (82), Expect = 2e-04

		 Identities = 24/90 (26%), Positives = 40/90 (44%), Gaps = 8/90 (8%)

		

		Query: 6   NTIKIGTR--NSPLALWQAKEVAAALEQKNYATEIVPIVSSGDKNLTQPLYSLGITGVFT 63

		            T +IG+   N  L+  +A+ V   L  K    + +     G+ N   P+       V  

		Sbjct: 260 YTDRIGSDAYNQGLSERRAQSVVDYLISKGIPADKISARGMGESN---PVTGNTCDNVKQ 316

		

		Query: 64  KDLDIALL--NKQIDIAVHSLKDVPTQLPQ 91

		           +   I  L  +++++I V  +KDV TQ PQ

		Sbjct: 317 RAALIDCLAPDRRVEIEVKGIKDVVTQ-PQ 345

		

		

		>PF05704#Capsular polysaccharide synthesis protein

		          Length = 307

		

		 Score = 48.0 bits (114), Expect = 1e-08

		 Identities = 31/151 (20%), Positives = 59/151 (39%), Gaps = 16/151 (10%)

		

		Query: 1   MIPKKIHYCWF-GRGEKSDFIKFCIDSWKKIQPDFEIIEWNEDNFDVY-GIPFTKEAYMQ 58

		           M  K I  CW  G  +    ++ C+ S KK   DF++I  + +N+  +  IP       Q

		Sbjct: 66  MRQKYIFICWLQGIEKAPYIVQQCVASVKKNSGDFKVIIIDGNNYKEWVDIPDFLIKRWQ 125

		

		Query: 59  KK---WAFVSDYARAKALYEHGGFYLDTDMELRLPLNDFLQHRAVCGFEMKGIPYSA--- 112

		           +     A+ SD  R   L ++GG ++D  + +   + +++       F+   +       

		Sbjct: 126 EGKMLDAWFSDILRLFLLCKYGGLWIDATVYMFDKVPNYIVESNRFMFQSSFLESETTHI 185

		

		Query: 113 ----FWAVEKGH----ELAKDIKEYYENKDK 135

		                +   K       L   +  Y + K+K

		Sbjct: 186 SNWLIFVKSKNDPFLVGLKNSMVTYLKKKEK 216

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score = 35.5 bits (82), Expect = 1e-04

		 Identities = 41/228 (17%), Positives = 78/228 (34%), Gaps = 49/228 (21%)

		

		Query: 7   LIASLFKEADLDNVIFFA--SGVSNSLE-------TSLAQFQREEELVRRTMEENLDKIF 57

		            +  LF     + V        V  SLE       ++L  F    E  R    ++L    

		Sbjct: 66  GMTDLFASGHFERVFISPHRLAVRYSLENPHAYADSNLTGFLNILEGCRHNKIQHL---- 121

		

		Query: 58  LYFSTCSIYDSSKA------------ESPYVLHKLKMEQVVVETCSQYLI----LRLSNV 101

		           LY S+ S+Y  ++              S Y   K   E +       Y +    LR   V

		Sbjct: 122 LYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKANELMAHTYSHLYGLPATGLRFFTV 181

		

		Query: 102 VGKGGNPNLLMNYLVNSVKRGEVINV--HTKATRNLIDAED-VKAVVFNLLKQKQLN--- 155

		            G  G P++ +     ++  G+ I+V  + K  R+    +D  +A++         +   

		Sbjct: 182 YGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFTYIDDIAEAIIRLQDVIPHADTQW 241

		

		Query: 156 --------------RVVNLAYIDNYTIIEILEILESVIKLKPNLNLIK 189

		                         RV N+       +++ ++ LE  + ++   N++ 

		Sbjct: 242 TVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDALGIEAKKNMLP 289

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 51.2 bits (122), Expect = 8e-09

		 Identities = 31/232 (13%), Positives = 61/232 (26%), Gaps = 22/232 (9%)

		

		Query: 202  LLEDFKKNEAVLTAELKQKQAQAKKIEGEIRKIINEEIAAAKAKEEAERKARLERERLAR 261

		                      + T    Q    +     E    ++E      A            E   +

		Sbjct: 987  KRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAENSKQ 1046

		

		Query: 262  EAAAREKARIDAENKARAEALERERKKAEAEAARLAEIERKKQDDARKQAELAKAEENAR 321

		            E+   EK   DA      E   + R+ A+   + +            +  E+A++    +

		Sbjct: 1047 ESKTVEKNEQDAT-----ETTAQNREVAKEAKSNV--------KANTQTNEVAQSGSETK 1093

		

		Query: 322  NEARRIAAEKDAREAAARAKA-AEEKAKAARDAEAELAKRK--EEEKKKAEEKTKTAFGV 378

		                    E    E   +AK   E+  +  +       K++  E  + +AE   +     

		Sbjct: 1094 ETQTTETKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQSETVQPQAEPAREN---- 1149

		

		Query: 379  GAATGSNFAENRGRIGFPVERGQVTHRFGRQPHPVFKNIVEENNGIRIAVSP 430

		                  N  E + +     +  Q                   N G  +  +P

		Sbjct: 1150 --DPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENP 1199

		

		

		

		 Score = 40.0 bits (93), Expect = 3e-05

		 Identities = 23/144 (15%), Positives = 40/144 (27%), Gaps = 12/144 (8%)

		

		Query: 226  KIEGEIRKIINEEIAAAKAKEEAERKARLERERLAREAAAREKARIDAENKARAEALERE 285

		            ++E   + +    I      +          E +AR   A       A      E +   

		Sbjct: 984  EVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTETVAEN 1043

		

		Query: 286  RKKAEAEAARLAEIERKKQDDARKQAELAKAEENARNEARRIAAEKDAREAAARAKAAEE 345

		             K+         E   +   +   Q      E  +  +A     E         A++  E

		Sbjct: 1044 SKQESKTV----EKNEQDATETTAQNREVAKEAKSNVKANTQTNEV--------AQSGSE 1091

		

		Query: 346  KAKAARDAEAELAKRKEEEKKKAE 369

		              +       E A  ++EEK K E

		Sbjct: 1092 TKETQTTETKETATVEKEEKAKVE 1115

		

		

		

		 Score = 36.2 bits (83), Expect = 4e-04

		 Identities = 21/197 (10%), Positives = 63/197 (31%), Gaps = 12/197 (6%)

		

		Query: 162  AEIQQALKLKQKSVKEKENILTQQQKDLLVIQNDRKQRELLLEDFKKNEAVLTAELKQKQ 221

		            A  Q     +  S  E +   T + K+   ++ + K +    +   +    +T+++  KQ

		Sbjct: 1078 ANTQTNEVAQSGS--ETKETQTTETKETATVEKEEKAKVETEK--TQEVPKVTSQVSPKQ 1133

		

		Query: 222  AQAKKIEGEIRKIINEEIAAAKAKEEAERKARLERERLAREAAAREKARIDAENKARAEA 281

		             Q++ ++ +       +      + +++     + E+ A+E ++  +  +          

		Sbjct: 1134 EQSETVQPQAEPARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGN 1193

		

		Query: 282  LERERKKAEAEAARLAEIERKKQDDARKQAELAKAEENARNEARRIAAEKDAREAAARAK 341

		               E  +    A          Q     ++       + R+        + A  ++    

		Sbjct: 1194 SVVENPENTTPAT--------TQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDRS 1245

		

		Query: 342  AAEEKAKAARDAEAELA 358

		                    + +  A L+

		Sbjct: 1246 TVALCDLTSTNTNAVLS 1262

		

		

		

		 Score = 34.7 bits (79), Expect = 0.001

		 Identities = 24/127 (18%), Positives = 46/127 (36%), Gaps = 6/127 (4%)

		

		Query: 253  RLERERLAREAAAREKARIDAENKARAEALERERKKAEAEAARLAEIERKKQDDARKQAE 312

		             L    + +     +   I   N  +A+         E      A +         +  E

		Sbjct: 979  DLYNPEVEKRNQTVDTTNITTPNNIQADVPSVPSNNEEIARVDEAPVPPPAPATPSETTE 1038

		

		Query: 313  LAKAEENARNEARRIA-AEKDAREAAARAKAAEEKAKAARDAE---AELAKRKEEEKKKA 368

		                 EN++ E++ +   E+DA E  A+ +   ++AK+   A     E+A+   E K+  

		Sbjct: 1039 T--VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQ 1096

		

		Query: 369  EEKTKTA 375

		              +TK  

		Sbjct: 1097 TTETKET 1103

		

		

		>MYCMG045#Hypothetical mycoplasma lipoprotein (MG045) signature.

		          Length = 483

		

		 Score = 29.3 bits (65), Expect = 0.019

		 Identities = 19/61 (31%), Positives = 30/61 (49%), Gaps = 5/61 (8%)

		

		Query: 30  FDSFTEETNGILAYIPKNDLNEDAIKSLYIFEQEGVEIDYTYTEMPNINWNEEWEKNFSP 89

		           FD +TE    +L      +LNE+  K +     E ++  YT  +  +I WN+  EK  SP

		Sbjct: 411 FDYYTETLKALLEKEDSAELNENEKKLV-----ETIKKAYTIEKDSSIRWNQLVEKPISP 465

		

		Query: 90  I 90

		           +

		Sbjct: 466 L 466

		

		

		>SACTRNSFRASE#Streptothricin acetyltransferase signature.

		          Length = 173

		

		 Score = 29.9 bits (67), Expect = 0.003

		 Identities = 13/101 (12%), Positives = 30/101 (29%), Gaps = 14/101 (13%)

		

		Query: 48  DGVGYVWVQGDEVLGYAVLMLNNEPAYDNIEGEWLSNGDYLVVHRVVVHDRCLGKGIAKQ 107

		               +++   +  +G   +  N           W     Y ++  + V      KG+   

		Sbjct: 64  GKAAFLYYLENNCIGRIKIRSN-----------W---NGYALIEDIAVAKDYRKKGVGTA 109

		

		Query: 108 MFLWIEGWAKQQNIYSVKVDTNYDNQPMLHILQHLGYQYCG 148

		           +      WAK+ +   + ++T   N    H      +    

		Sbjct: 110 LLHKAIEWAKENHFCGLMLETQDINISACHFYAKHHFIIGA 150

		

		

		>BINARYTOXINB#Binary toxin B family signature.

		          Length = 764

		

		 Score = 28.5 bits (63), Expect = 0.026

		 Identities = 12/38 (31%), Positives = 19/38 (50%), Gaps = 1/38 (2%)

		

		Query: 163 ESGKTILIETDAVYGANDAFYEAKGSYSFMHTCNTWAN 200

		           E  K + ++TD VYG N A Y  +     + T + W+ 

		Sbjct: 472 EKTKQLRLDTDQVYG-NIATYNFENGRVRVDTGSNWSE 508

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 29.4 bits (66), Expect = 0.014

		 Identities = 9/57 (15%), Positives = 22/57 (38%), Gaps = 11/57 (19%)

		

		Query: 189 DIKSAAAGTILFAGEKSGYGKCVIISHGNGLATLYGHLSQVLVKANDKIKAGETIAK 245

		           +I + A G +  +G          I            + +++VK  + ++ G+ + K

		Sbjct: 81  EIVATANGKLTHSGRS------KEIKPIEN-----SIVKEIIVKEGESVRKGDVLLK 126

		

		

		>IGASERPTASE#IgA-specific serine endopeptidase (S6) signature.

		          Length = 1541

		

		 Score = 39.7 bits (92), Expect = 4e-05

		 Identities = 35/249 (14%), Positives = 71/249 (28%), Gaps = 23/249 (9%)

		

		Query: 201  TELTASQNIKANLVRREEEKTIKKQDVE-AREAILELEKQLAEKEETQ-KREVENIKARE 258

		                + Q  K      ++      Q+ E A+EA   ++      E  Q   E +  +  E

		Sbjct: 1040 VAENSKQESKTVEKNEQDATETTAQNREVAKEAKSNVKANTQTNEVAQSGSETKETQTTE 1099

		

		Query: 259  NAEILKVAEEERLKYESVRIATEEALQIAEENKQRQVVIAAKNKERADLVETERVQKDKM 318

		              E   V +EE+ K E+ +      +      KQ Q              ET + Q +  

		Sbjct: 1100 TKETATVEKEEKAKVETEKTQEVPKVTSQVSPKQEQ-------------SETVQPQAEP- 1145

		

		Query: 319  LEATERERIVALADIEKDKAVELEKKNIQDVIRE--RLAKEKTVVEEQQNIYDVEALKSA 376

		              A E +  V + + +       + +               ++      N        + 

		Sbjct: 1146 --ARENDPTVNIKEPQSQTNTTADTEQPAKETSSNVEQPVTESTTVNTGNSVVENPENTT 1203

		

		Query: 377  ERDKQVQLIIAAREAEERLIAETKAAEARKLAAEKDAQKYVIEAQAKRDAAEKEAEARKI 436

		                Q  +   +    +     +  +    +     +        A  D       A  +

		Sbjct: 1204 PATTQPTVNSESSNKPKNRHRRSVRSVPHNVEPATTSSNDR-STVALCDLTSTNTNA--V 1260

		

		Query: 437  IADALAKEE 445

		            ++DA AK +

		Sbjct: 1261 LSDARAKAQ 1269

		

		

		>TCRTETB#Tetracycline resistance protein TetB signature.

		          Length = 458

		

		 Score = 33.7 bits (77), Expect = 0.002

		 Identities = 26/126 (20%), Positives = 49/126 (38%), Gaps = 4/126 (3%)

		

		Query: 48  LSIDPAQASLIYGYFTGFVYFTPLIGGWLADKFLGQRLSITIGGVLMMLGQFTLFAINTH 107

		            +  PA  + +   F         + G L+D+   +RL +  G ++   G    F  ++ 

		Sbjct: 44  FNKPPASTNWVNTAFMLTFSIGTAVYGKLSDQLGIKRLLL-FGIIINCFGSVIGFVGHSF 102

		

		Query: 108 FGLYI-GLLLLIIGNGFFKPNISVLVGNLYEEGDERRDSAFSIFYMGINLGALIAPLVIG 166

		           F L I    +   G   F   + V+V     +  E R  AF +    + +G  + P + G

		Sbjct: 103 FSLLIMARFIQGAGAAAFPALVMVVVARYIPK--ENRGKAFGLIGSIVAMGEGVGPAIGG 160

		

		Query: 167 VLTDDI 172

		           ++   I

		Sbjct: 161 MIAHYI 166

		

		

		>cdtoxina#Cytolethal distending toxin A signature.

		          Length = 258

		

		 Score = 30.1 bits (67), Expect = 0.004

		 Identities = 11/27 (40%), Positives = 15/27 (55%)

		

		Query: 5  IILTGLLSLGLLTGCNSQKQNDMNEPK 31

		          I + G+L   LL GC+S K     +PK

		Sbjct: 8  IFIAGILIPILLNGCSSGKNKAYLDPK 34

		

		

		>PF05043#Transcriptional activator

		          Length = 493

		

		 Score = 26.1 bits (57), Expect = 0.048

		 Identities = 16/88 (18%), Positives = 35/88 (39%), Gaps = 3/88 (3%)

		

		Query: 5   TKKDYQRYLQEVDELMKKGEELLTSTELNRISVLSSALEEYEDAFYPIAQPKTLPEMVEL 64

		           T++  +  L  V        +L+  +  N I ++++   + E  ++   +  T   ++E 

		Sbjct: 38  TERAVKDDLSHVKSAFP---DLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEF 94

		

		Query: 65  RLFEKKMSQTDFAKVSGISLSKVNQIIK 92

		             F +        K   IS S + +II 

		Sbjct: 95  IFFNEGCQAESICKEFYISSSSLYRIIS 122

		

		

		>TYPE4SSCAGX#Type IV secretion system CagX conjugation protein

		           signature.

		          Length = 522

		

		 Score = 31.7 bits (71), Expect = 0.026

		 Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 9/131 (6%)

		

		Query: 545 KETEKQTQVFADMAEEQERISAKYNADRQKREEEEAKKQQTSLSNTANETKKKAKAHQKA 604

		           KE E+Q +      E +E+        R+KR+EE AK +    + T   +  +  ++ K 

		Sbjct: 139 KELEEQKKALEKEKEAKEQAQKAQKDKREKRKEERAKNRANLENLTNAMSNPQNLSNNKN 198

		

		Query: 605 LAEVYSKNSIKDLEERISLWN-------NALERATK--DKDGNYQVKVRGKDKYGKEYET 655

		           L+E+  +    +L++   L +       NAL++  +   K     V+ R KDK   + + 

		Sbjct: 199 LSELIKQQRENELDQMERLEDMQEQAQANALKQIEELNKKQAEEAVRQRAKDKISIKTDK 258

		

		Query: 656 GQVVSKDKALE 666

		            Q   +D ++E

		Sbjct: 259 SQKSPEDNSIE 269

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 27.9 bits (62), Expect = 0.037

		 Identities = 13/80 (16%), Positives = 25/80 (31%), Gaps = 16/80 (20%)

		

		Query: 102 GAYALPQTFAEALKLAAQQAERLELQQAELKKQAPKVAYYEEVLQSESTYNTNQIAKELG 161

		            ++      +        + E   +  A L                    N  + A  LG

		Sbjct: 417 ASFGDALPPSGLYDRVLAEMEYPLILAA-LTATR---------------GNQIKAADLLG 460

		

		Query: 162 MSAITLNKKLQDLKVQYRQG 181

		           ++  TL KK+++L V   + 

		Sbjct: 461 LNRNTLRKKIRELGVSVYRS 480

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score = 24.1 bits (52), Expect = 0.038

		 Identities = 8/26 (30%), Positives = 18/26 (69%)

		

		Query: 34  YDDDKKEKEIDLTEQTPEDLEKMLEK 59

		           +  D+K ++++LTE+    +E++L K

		Sbjct: 263 FSVDEKSRQVNLTERGLVLIEELLVK 288

		

		

		>BONTOXILYSIN#Bontoxilysin signature.

		          Length = 1196

		

		 Score = 27.9 bits (62), Expect = 0.039

		 Identities = 10/37 (27%), Positives = 20/37 (54%), Gaps = 3/37 (8%)

		

		Query: 4   KYNKQLKFRDLGLMDYPDAFEYQENLMKEIIELKLKN 40

		           +Y  Q  + +L  M    +   QE+L+K+I++ K  +

		Sbjct: 675 EYYSQ--YFELICMAK-QSILAQESLVKQIVQNKFTD 708

		

		

		>ECOLIPORIN#E.coli/Salmonella-type porin signature.

		          Length = 383

		

		 Score = 26.4 bits (58), Expect = 0.034

		 Identities = 13/43 (30%), Positives = 23/43 (53%)

		

		Query: 24 VEHRNDNSEMSFGQFITLHYFSGDVHDDDYEEDMKLPFKSQNQ 66

		          + +++ N    +G+   LHYFS D   D  +  M++ FK + Q

		Sbjct: 24 IYNKDGNKLDLYGKVDGLHYFSDDSSKDGDQTYMRVGFKGETQ 66

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score =  691 bits (1785), Expect = 0.0

		 Identities = 224/1052 (21%), Positives = 423/1052 (40%), Gaps = 47/1052 (4%)

		

		Query: 23   FSIKNKLIIGLFTLALIIYGIFEVRKLPIDAVPDITDNQVQIITVSPSLGAPDVERFITF 82

		            F I+  +   +  + L++ G   + +LP+   P I    V +    P   A  V+  +T 

		Sbjct: 4    FFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDTVTQ 63

		

		Query: 83   PLEQANNNIQGIKQIRSFS-RFGLSVITIVFKDDVDIHLARQQVSERLQQVSKDIPAELG 141

		             +EQ  N I  +  + S S   G   IT+ F+   D  +A+ QV  +LQ  +  +P E+ 

		Sbjct: 64   VIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQEVQ 123

		

		Query: 142  VPTMAPITTGLGEIYQYVVRPKKGYEHRYDAMKLRTIQDWVVRRQLLGIEGVADVASFGG 201

		               ++   +    +                   +       V+  L  + GV DV  FG 

		Sbjct: 124  QQGISVEKSSSSYLMVAGFVSDNPG---TTQDDISDYVASNVKDTLSRLNGVGDVQLFGA 180

		

		Query: 202  YLKQYEIAINPTQLKAMGVTMQEVFNALQSNNQNTGGAYIEKGPTV------LFIRTEGL 255

		                  I ++   L    +T  +V N L+  N       +   P +        I  +  

		Sbjct: 181  Q-YAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239

		

		Query: 256  VGKIEDIENTVVKTLPDGTPILVKNIGNVGYGSATRYGAMTYNGKGEVAGAVVMMMKGAN 315

		                E+     ++   DG+ + +K++  V  G          NGK   AG  + +  GAN

		Sbjct: 240  FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGK-PAAGLGIKLATGAN 298

		

		Query: 316  SNQVIKNVKERIDEIQKTLPEGVKIEPFLDRTKMVNNAIGTVQKNLMEGALIVIFVLVLF 375

		            +    K +K ++ E+Q   P+G+K+    D T  V  +I  V K L E  ++V  V+ LF

		Sbjct: 299  ALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358

		

		Query: 376  LGNFRAGFLVASVIPLSMLFAIIMMNIFGVSGNLMSLG--ALDFGLIVDGAVIIVEAVLH 433

		            L N RA  +    +P+ +L    ++  FG S N +++    L  GL+VD A+++VE V  

		Sbjct: 359  LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENV-E 417

		

		Query: 434  KLHELKKSDKSELSQQEMNDEVESSAGKMMNSAVFGQIIILIVYLPILTLQGIEGKMFKP 493

		            ++    K    E +++ M         ++  + V   +++  V++P+    G  G +++ 

		Sbjct: 418  RVMMEDKLPPKEATEKSM--------SQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQ 469

		

		Query: 494  MAQTVAFALLGAFILSLTYVPMMSSLVLSKKINFKK-------NFSDKMMEKVEAFYEKT 546

		             + T+  A+  + +++L   P + + +L                + +   +     Y  +

		Sbjct: 470  FSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENKGGFFGWFNTTFDHSVNHYTNS 529

		

		Query: 547  LAKILNRSKVVVIAILALFVFSVFILTRLGGEFIPSLPEGDFAVDTRVLTGSNLKTSTDA 606

		            + KIL  +   ++    +    V +  RL   F+P   +G F    ++  G+  + +   

		Sbjct: 530  VGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKV 589

		

		Query: 607  VQKSSQILLKK-FPEIEKIVGKTGSSEIPTDPMPIDASDMMVILKPREEWTSAKTYEELS 665

		            + + +   LK     +E +    G S         +A    V LKP EE       E  +

		Sbjct: 590  LDQVTDYYLKNEKANVESVFTVNGFS---FSGQAQNAGMAFVSLKPWEERN---GDENSA 643

		

		Query: 666  EKMSAELKKNMLGVTYSFQYPVNM-RFNELMTGARQDV-VCKIFGENLDTLKVYSEKL-G 722

		            E +    K  +  +   F  P NM    EL T    D  +    G   D L     +L G

		Sbjct: 644  EAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFELIDQAGLGHDALTQARNQLLG 703

		

		Query: 723  EISKGIKGAQNIYVEPISGIPQIVISYNRAKIAQYGVNISEINRIVNTAFAGQSTGSVYE 782

		              ++      ++    +    Q  +  ++ K    GV++S+IN+ ++TA  G       +

		Sbjct: 704  MAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFID 763

		

		Query: 783  GEKRFDLVVRLSGEQRKNIDDVRNLLISTPSGTEIPLSSIADVELKESVNQIQRENAQRR 842

		              +   L V+   + R   +DV  L + + +G  +P S+           +++R N    

		Sbjct: 764  RGRVKKLYVQADAKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPS 823

		

		Query: 843  IIVGFNVRNRDIQTTVADLQTQVEQ-KLKLPPGYFIKYGGTFENLQQAKARLSIAVPASL 901

		            + +           +  D    +E    KLP G    + G     + +  +    V  S 

		Sbjct: 824  MEIQGEAAPGT---SSGDAMALMENLASKLPAGIGYDWTGMSYQERLSGNQAPALVAISF 880

		

		Query: 902  LMIFLMLYFAFRSIKYGMLIFTAIPLSAIGGILALWLRGMNFSISAGVGFIALFGVAVLN 961

		            +++FL L   + S    + +   +PL  +G +LA  L      +   VG +   G++  N

		Sbjct: 881  VVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKN 940

		

		Query: 962  GIVLIAEFNRQKALQ--TSLKDAVRAGGKNRLRPVLMTAFVASLGFLPMATSTGEGAEVQ 1019

		             I+++ EF +    +    + +A     + RLRP+LMT+    LG LP+A S G G+  Q

		Sbjct: 941  AILIV-EFAKDLMEKEGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQ 999

		

		Query: 1020 RPLATVVIGGLLLATFLTLYLLPILYIWFESK 1051

		              +   V+GG++ AT L ++ +P+ ++     

		Sbjct: 1000 NAVGIGVMGGMVSATLLAIFFVPVFFVVIRRC 1031

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 43.3 bits (102), Expect = 1e-06

		 Identities = 40/208 (19%), Positives = 67/208 (32%), Gaps = 37/208 (17%)

		

		Query: 113 LVQLQQDYLLAKSNFGYAEKDYQRQK---DLNQSQASSDKAMQMAHTEAKNQNISINALA 169

		            V+   +  + KS     E +    K    L      ++   ++  T        I  L 

		Sbjct: 261 YVEAVNELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDN-----IGLLT 315

		

		Query: 170 ERLRILGVNPDKITPQSIQRSVALRAPISGYITRVNVN-IGQYVSPVDKLFEIVNTQDTH 228

		             L               Q++  +RAP+S  + ++ V+  G  V+  + L  IV   DT 

		Sbjct: 316 LELAKNEER---------QQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVIVPEDDTL 366

		

		Query: 229 LV-LKAFEKDLSHLKIGQ----KVYAYANQNPDKKYTASIILIGKNFDSD---------- 273

		            V      KD+  + +GQ    KV A+            +  I  +   D          

		Sbjct: 367 EVTALVQNKDIGFINVGQNAIIKVEAF-PYTRYGYLVGKVKNINLDAIEDQRLGLVFNVI 425

		

		Query: 274 RSVPVHCHFVGGQP-DLVPGSFMNADVE 300

		            S+  +C   G +   L  G  M    E

		Sbjct: 426 ISIEENCLSTGNKNIPLSSG--MAVTAE 451

		

		

		

		 Score = 39.0 bits (91), Expect = 2e-05

		 Identities = 17/102 (16%), Positives = 29/102 (28%), Gaps = 7/102 (6%)

		

		Query: 59  EISSKITLNGNIDVPPQGMASVSSPSGGYIKSAKFMPGNFVNKGDVLAILEDP----NLV 114

		           ++    T NG +         +       +K      G  V KGDVL  L       + +

		Sbjct: 79  QVEIVATANGKL-THSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTL 137

		

		Query: 115 QLQQDYLLAKSNFG--YAEKDYQRQKDLNQSQASSDKAMQMA 154

		           + Q   L A+                 L + +   +   Q  

		Sbjct: 138 KTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYFQNV 179

		

		

		>PF05844#YopD protein

		          Length = 295

		

		 Score = 27.7 bits (61), Expect = 0.047

		 Identities = 19/108 (17%), Positives = 32/108 (29%), Gaps = 9/108 (8%)

		

		Query: 150 ADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQEAFEMGMVNKVVPHEELEDTAYE 209

		           A  ++  G  G+    K + Q+K  +    GRN       +M  + K    E+ +     

		Sbjct: 131 ALASAVVGSLGALKNGKAISQEKTLQKNIDGRNELIDA--KMQALGKTS-DEDRKIVGKV 187

		

		Query: 210 WAQEILAKSPTSIRM-LKFAMNLTDDGMVGQQVFAGEATRLAYMTDEA 256

		           WA +    S         F            QV          M + +

		Sbjct: 188 WAADQAQDSVALRAAGRAFESR-----NGALQVANTVIQSFVQMANAS 230

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score = 78.9 bits (194), Expect = 2e-19

		 Identities = 49/194 (25%), Positives = 90/194 (46%), Gaps = 3/194 (1%)

		

		Query: 2   SKKFQHKNILITGGASGIGKIMARLSLEKGAKVIIWDIDQSKIDETILQFSSLG-SIFGY 60

		           +K  + K   ITG A GIG+ +AR    +GA +   D +  K+++ +    +       +

		Sbjct: 3   AKGIEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAF 62

		

		Query: 61  KVDVSNYDEVQHFAIKTKQKIGNVDILINNAGIVVGKYFHEHSQKDILKTIEINTNAPMV 120

		             DV +   +     + ++++G +DIL+N AG++     H  S ++   T  +N+     

		Sbjct: 63  PADVRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFN 122

		

		Query: 121 ITNLFLQDMLTQNSGHICNIASSAGLVSNPKMSVYAGSKWAVVGWSDSLRLEMEQLKKNI 180

		            +    + M+ + SG I  + S+   V    M+ YA SK A V ++  L LE+ +   NI

		Sbjct: 123 ASRSVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAE--YNI 180

		

		Query: 181 KVTTIMPYYINTGM 194

		           +   + P    T M

		Sbjct: 181 RCNIVSPGSTETDM 194

		

		

		>SHAPEPROTEIN#Bacterial cell shape determinant MreB/Mbl protein

		           signature.

		          Length = 347

		

		 Score = 62.5 bits (152), Expect = 9e-13

		 Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 23/216 (10%)

		

		Query: 151 KRLEANFHVVVGQMSSIKNIS-RCVKE----AGLEMESLTLEPLASSEAVLTKEEKEAGV 205

		             +  +  V+V        +  R ++E    AG     L  EP+A++        +  G 

		Sbjct: 102 SFMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATGS 161

		

		Query: 206 AIVDIGGGTTDIAIFKDNIIRHTCVIPYGGGIITEDI------KDGCSIIEKHAEQLKVR 259

		            +VDIGGGTT++A+   N + ++  +  GG    E I        G  I E  AE++K  

		Sbjct: 162 MVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERIKHE 221

		

		Query: 260 FGSAVPELEKESTFVTIPGLHGRTEKEISLKTLAKIIHARVEEILEMVNTELKAYGAHEK 319

		            GSA P  E     V      GR   E   +      +  +E + E +   + A     +

		Sbjct: 222 IGSAYPGDEVREIEV-----RGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE 276

		

		Query: 320 KRK--LIA-----GIVLTGGGSNLKHLRQLANYITG 348

		           +    L +     G+VLTGGG+ L++L +L    TG

		Sbjct: 277 QCPPELASDISERGMVLTGGGALLRNLDRLLMEETG 312

		

		

		>TOXICSSTOXIN#Staphylococcal toxic shock syndrome toxin signature.

		          Length = 234

		

		 Score = 28.8 bits (64), Expect = 0.013

		 Identities = 29/149 (19%), Positives = 53/149 (35%), Gaps = 25/149 (16%)

		

		Query: 81  QRVPVFRLSKGKKEFYVDEKGVEFPINRNYSASCMLISGNVQPEEYPQLIE--LVKKINQ 138

		              P F   +         K  +      Y      ISG    E+ P  IE  L  K++ 

		Sbjct: 91  YYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQ--ISGVTNTEKLPTPIELPLKVKVHG 148

		

		Query: 139 DDFSKKFFIGVVKERENYYLIANEENYRVELGSLENIDFKVKGFKAFVEKYLVYQPSDK- 197

		            D   K+                ++       ++  +DF+++      + + +Y+ SDK 

		Sbjct: 149 KDSPLKY----------GPKFDKKQL------AISTLDFEIR--HQLTQIHGLYRSSDKT 190

		

		Query: 198 --YTKISLKYDNQIVTTLSKGYKEETYKE 224

		             Y KI++   +   + LSK ++  T K 

		Sbjct: 191 GGYWKITMNDGSTYQSDLSKKFEYNTEKP 219

		

		

		>SALSPVBPROT#Salmonella virulence plasmid 65kDa B protein signature.

		          Length = 591

		

		 Score = 29.7 bits (66), Expect = 0.024

		 Identities = 19/60 (31%), Positives = 30/60 (50%), Gaps = 3/60 (5%)

		

		Query: 160 KDYSVVEADEYDRSFLNLAPDWAIITSTDADHLDIYGDKSTIEKGFRDFAHLVSEERQLF 219

		           K+Y+ +     D++F++ +PD A I  T    L+IY +K    +   D AH   E   LF

		Sbjct: 485 KEYTTIGNIIIDKAFMSTSPDKAWINDTI---LNIYLEKGHKGRILGDVAHFKGEAEMLF 541

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 50.2 bits (120), Expect = 6e-09

		 Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 6/95 (6%)

		

		Query: 59  EVRAQGKGFLDKIYVDEGQYVKAGQVLFRIMPQVYEAELMKTRAEVEQARIEYQNASILA 118

		           E++      + +I V EG+ V+ G VL ++     EA+ +KT++ + QAR+E        

		Sbjct: 98  EIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQARLE--QTRYQI 155

		

		Query: 119 GNNIVSKNE----KALAKAKLDAASAEMRMAQLHL 149

		            +  +  N+    K   +      S E  +    L

		Sbjct: 156 LSRSIELNKLPELKLPDEPYFQNVSEEEVLRLTSL 190

		

		

		

		 Score = 39.0 bits (91), Expect = 2e-05

		 Identities = 25/109 (22%), Positives = 51/109 (46%), Gaps = 8/109 (7%)

		

		Query: 75  EGQYVKAGQVLFRIMPQVYEAELMKTRAEVEQARIEYQNASILAGNNIVSKNEKALAKAK 134

		           E +YV+A   L     +VY+++L +  +E+  A+ EYQ  + L  N I+ K  +      

		Sbjct: 258 ENKYVEAVNEL-----RVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQT--TDN 310

		

		Query: 135 LDAASAEMRMAQLHLSFTTIRAPFSGIINRIPLK-LGSLIEEGDLLTSL 182

		           +   + E+   +     + IRAP S  + ++ +   G ++   + L  +

		Sbjct: 311 IGLLTLELAKNEERQQASVIRAPVSVKVQQLKVHTEGGVVTTAETLMVI 359

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score =  913 bits (2360), Expect = 0.0

		 Identities = 376/1037 (36%), Positives = 582/1037 (56%), Gaps = 11/1037 (1%)

		

		Query: 1    MFKTFIKRPVLSIVISLIIVFLGVLSLLSLPITQFPSISPPKVNITAEYPGANNELLVKS 60

		            M   FI+RP+ + V+++I++  G L++L LP+ Q+P+I+PP V+++A YPGA+ + +  +

		Sbjct: 1    MANFFIRRPIFAWVLAIILMMAGALAILQLPVAQYPTIAPPAVSVSANYPGADAQTVQDT 60

		

		Query: 61   VVIPLEQALNGVQGMKYITSDAGNDGVASIQVVFNLGTDPNLAAVNVQNRVSSAINKLPP 120

		            V   +EQ +NG+  + Y++S + + G  +I + F  GTDP++A V VQN++  A   LP 

		Sbjct: 61   VTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDIAQVQVQNKLQLATPLLPQ 120

		

		Query: 121  LVVREGVKITREEPNMLMYVNLYSDDPKADQKFLFNYADINILPELRRVNGVGFADILGT 180

		             V ++G+ + +   + LM     SD+P   Q  + +Y   N+   L R+NGVG   + G 

		Sbjct: 121  EVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVASNVKDTLSRLNGVGDVQLFG- 179

		

		Query: 181  REYAMRIWLKPDRLTAYNISTDEVMEALSSQSLEASPGRTGESSGKRSQAFEYVLKYPGR 240

		             +YAMRIWL  D L  Y ++  +V+  L  Q+ + + G+ G +     Q     +    R

		Sbjct: 180  AQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQLGGTPALPGQQLNASIIAQTR 239

		

		Query: 241  FDNEKDYGNIIVKANSNGEFVRLKDVADVEFGSSMYDIYSTLNGKPSAAITIKQSYGSNA 300

		            F N +++G + ++ NS+G  VRLKDVA VE G   Y++ + +NGKP+A + IK + G+NA

		Sbjct: 240  FKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYNVIARINGKPAAGLGIKLATGANA 299

		

		Query: 301  SEVIKNVKTLLEELNKTSFPKGMHYEISYDVSRFLDASMEKVVHTLFEAFVLVGIVVFIF 360

		             +  K +K  L EL +  FP+GM     YD + F+  S+ +VV TLFEA +LV +V+++F

		Sbjct: 300  LDTAKAIKAKLAEL-QPFFPQGMKVLYPYDTTPFVQLSIHEVVKTLFEAIMLVFLVMYLF 358

		

		Query: 361  LGDWRSTLIPALAVPVSLIGAFAVMSSFGITVNMITLFALVMAIGVVVDDAIVVIEAVHA 420

		            L + R+TLIP +AVPV L+G FA++++FG ++N +T+F +V+AIG++VDDAIVV+E V  

		Sbjct: 359  LQNMRATLIPTIAVPVVLLGTFAILAAFGYSINTLTMFGMVLAIGLLVDDAIVVVENVER 418

		

		Query: 421  KMEEKHLSPLEATQEAMGEISGAIIAITLVMAAVFIPVAFMSGPVGVFYRQFSITMASSI 480

		             M E  L P EAT+++M +I GA++ I +V++AVFIP+AF  G  G  YRQFSIT+ S++

		Sbjct: 419  VMMEDKLPPKEATEKSMSQIQGALVGIAMVLSAVFIPMAFFGGSTGAIYRQFSITIVSAM 478

		

		Query: 481  ILSGIVALTLTPALCALILKNNHGKERKKTPINRFIDGFNRVFAKGTKRYETLLYKTVSK 540

		             LS +VAL LTPALCA +LK              F   FN  F      Y   + K +  

		Sbjct: 479  ALSVLVALILTPALCATLLKPV--SAEHHENKGGFFGWFNTTFDHSVNHYTNSVGKILGS 536

		

		Query: 541  KWITLGGLSVFCFLVYFLNNGLPSGFIPNEDQGMIYAIVQTPPGSTIERTNQQALKIQKI 600

		                L   ++    +  L   LPS F+P EDQG+   ++Q P G+T ERT +   ++   

		Sbjct: 537  TGRYLLIYALIVAGMVVLFLRLPSSFLPEEDQGVFLTMIQLPAGATQERTQKVLDQVTDY 596

		

		Query: 601  AEGIEGVKSVSSLAGYEILSEGTGANSGTCLINLKNWDERDK---SATEIIEELEEKCKD 657

		                E     S          G   N+G   ++LK W+ER+    SA  +I   + +   

		Sbjct: 597  YLKNEKANVESVFTVNGFSFSGQAQNAGMAFVSLKPWEERNGDENSAEAVIHRAKMELGK 656

		

		Query: 658  IGGSNIEFFQPPSIPGYGAAGGFELRLLDKTGSNDYAKMEEVSRNFVKELSKRP-ELASV 716

		            I    +  F  P+I   G A GF+  L+D+ G   +  + +     +   ++ P  L SV

		Sbjct: 657  IRDGFVIPFNMPAIVELGTATGFDFELIDQAG-LGHDALTQARNQLLGMAAQHPASLVSV 715

		

		Query: 717  FTFYSASFPQYMLKVDNDIAEQKGVSIGSAMNNLSTLIGSNYETGFIRFGKPYKVIVQAA 776

		                     Q+ L+VD + A+  GVS+      +ST +G  Y   FI  G+  K+ VQA 

		Sbjct: 716  RPNGLEDTAQFKLEVDQEKAQALGVSLSDINQTISTALGGTYVNDFIDRGRVKKLYVQAD 775

		

		Query: 777  PQYRALPQDIMNLYVKNDKEEMVPYSDFMHMEKVYGMSEITRHNMYNSAQISGYPSEGYS 836

		             ++R LP+D+  LYV++   EMVP+S F     VYG   + R+N   S +I G  + G S

		Sbjct: 776  AKFRMLPEDVDKLYVRSANGEMVPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTS 835

		

		Query: 837  SGQAIEAIKETADKTLPRGYGIDWAGISKDEVGRGNEAVYIFLICLGFVYLILSAQYESF 896

		            SG A+  ++  A K LP G G DW G+S  E   GN+A  +  I    V+L L+A YES+

		Sbjct: 836  SGDAMALMENLASK-LPAGIGYDWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESW 894

		

		Query: 897  ILPLPVILCLPAGIFGAFLFLKLFGLENNIYAQVALVMLIGLLGKNAVLIVEYAVQRK-N 955

		             +P+ V+L +P GI G  L   LF  +N++Y  V L+  IGL  KNA+LIVE+A      

		Sbjct: 895  SIPVSVMLVVPLGIVGVLLAATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEK 954

		

		Query: 956  EGATILKAAIEGAVTRFRPILMTSFAFIAGLIPLALATGPGAIGNRTIGTAAAGGMFIGT 1015

		            EG  +++A +     R RPILMTS AFI G++PLA++ G G+     +G    GGM   T

		Sbjct: 955  EGKGVVEATLMAVRMRLRPILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSAT 1014

		

		Query: 1016 IFGVVLIPGLYLIFGKI 1032

		            +  +  +P  +++  + 

		Sbjct: 1015 LLAIFFVPVFFVVIRRC 1031

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score = 30.6 bits (69), Expect = 0.015

		 Identities = 23/139 (16%), Positives = 41/139 (29%), Gaps = 19/139 (13%)

		

		Query: 180 LSSLIAEVAQSYYELLALDSQYSYLKKYIELQRKALEVSKIQKQAAATTELSVKKFEAEL 239

		           L    AE       +   ++     K  ++     L    I K A    E    +   EL

		Sbjct: 209 LDKKRAERLTVLARINRYENLSRVEKSRLDDFSSLLHKQAIAKHAVLEQENKYVEAVNEL 268

		

		Query: 240 AKSSANLYTVQQSILEKENDINLLLGRFYQPIPRSSAEFLDIVPQSIKTGIPSELLANRP 299

		               + L  ++  IL  + +  L+                    Q  K  I  +L     

		Sbjct: 269 RVYKSQLEQIESEILSAKEEYQLV-------------------TQLFKNEILDKLRQTTD 309

		

		Query: 300 DVKQAELELEAAKLDVEAA 318

		           ++    LEL   +   +A+

		Sbjct: 310 NIGLLTLELAKNEERQQAS 328

		

		

		>SYCDCHAPRONE#Gram-negative bacterial type III secretion SycD

		           chaperone signature.

		          Length = 168

		

		 Score = 38.4 bits (89), Expect = 2e-05

		 Identities = 21/124 (16%), Positives = 42/124 (33%), Gaps = 4/124 (3%)

		

		Query: 201 FEYGQFYFNRKNYEEAIRGFDYFLAINSNSVGVYANKAACYEAMQEWDKAVEVYEEMLEL 260

		           +      +    YE+A + F     ++      +    AC +AM ++D A+  Y     +

		Sbjct: 40  YSLAFNQYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIM 99

		

		Query: 261 EYTKAYTYYKIGLCHKENKKPLLALKSFQKSLVEDPQFYLSMMEQSFLYEEMGQMKEALH 320

		           +  +    +    C  +  +   A    +  L    +      E   L   +  M EA+ 

		Sbjct: 100 DIKEPRFPFHAAECLLQKGELAEA----ESGLFLAQELIADKTEFKELSTRVSSMLEAIK 155

		

		Query: 321 FAKE 324

		             KE

		Sbjct: 156 LKKE 159

		

		

		

		 Score = 32.2 bits (73), Expect = 0.002

		 Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 7/69 (10%)

		

		Query: 252 EVYEEMLELEYTKAYTYYKIGLCHKENKKPLLALKSFQKSLVEDPQFYLSMMEQSFLYEE 311

		           E+  + LE  Y+ A+  Y+ G       K   A K FQ   V D       +      + 

		Sbjct: 30  EISSDTLEQLYSLAFNQYQSG-------KYEDAHKVFQALCVLDHYDSRFFLGLGACRQA 82

		

		Query: 312 MGQMKEALH 320

		           MGQ   A+H

		Sbjct: 83  MGQYDLAIH 91

		

		

		

		 Score = 28.7 bits (64), Expect = 0.031

		 Identities = 16/88 (18%), Positives = 26/88 (29%)

		

		Query: 173 FYKLNKNDDAIKFLNHYIEEFPFSETAWFEYGQFYFNRKNYEEAIRGFDYFLAINSNSVG 232

		            Y+  K +DA K          +    +   G        Y+ AI  + Y   ++     

		Sbjct: 46  QYQSGKYEDAHKVFQALCVLDHYDSRFFLGLGACRQAMGQYDLAIHSYSYGAIMDIKEPR 105

		

		Query: 233 VYANKAACYEAMQEWDKAVEVYEEMLEL 260

		              + A C     E  +A        EL

		Sbjct: 106 FPFHAAECLLQKGELAEAESGLFLAQEL 133

		

		

		>PF03309#Bvg accessory factor

		          Length = 271

		

		 Score =  198 bits (504), Expect = 4e-65

		 Identities = 75/257 (29%), Positives = 125/257 (48%), Gaps = 16/257 (6%)

		

		Query: 4   IVVNIGNTNIRFGLFNNEGCSL----SWVINTKPYRTKDELFVQFLMHYQSYDIKPKEID 59

		           + +++ NT+   GL +  G        W I T+P  T DEL +             + + 

		Sbjct: 3   LAIDVRNTHTVVGLISGSGDHAKVVQQWRIRTEPEVTADELALTID---GLIGDDAERLT 59

		

		Query: 60  QLIIGSVVPQMTNDIVRALEKIHHLKPILV---DRNTPSEVKPKS-KQMGTDIYANLVAA 115

		                S VP + +++   LE+     P ++      T   +   + K++G D   N +AA

		Sbjct: 60  GASGLSTVPSVLHEVRVMLEQYWPNVPHVLIEPGVRTGIPLLVDNPKEVGADRIVNCLAA 119

		

		Query: 116 HHLYPNKSKIIFDFGTALTASCISHSGETLGAIIAPGIITSLKSLIQDTAQLLEIELQAP 175

		           +H Y   + I+ DFG+++    +S  GE LG  IAPG+  S  +    +A L  +EL  P

		Sbjct: 120 YHKYG-TAAIVVDFGSSICVDVVSAKGEFLGGAIAPGVQVSSDAAAARSAALRRVELTRP 178

		

		Query: 176 KSVLGLDTVSCMQSGMVYGYLGMVEGFIERINREI----GEEAFVIATGGVSHVYKPLSD 231

		           +SV+G +TV CMQ+G V+G+ G+V+G + RI  ++    G +  V+ATG  + +  P   

		Sbjct: 179 RSVIGKNTVECMQAGAVFGFAGLVDGLVNRIRDDVDGFSGADVAVVATGHTAPLVLPDLR 238

		

		Query: 232 KIHIADRLHTLKGLYFL 248

		            +   DR  TL GL  +

		Sbjct: 239 TVEHYDRHLTLDGLRLV 255

		

		

		>PF06580#Sensor histidine kinase

		          Length = 349

		

		 Score = 39.8 bits (93), Expect = 2e-05

		 Identities = 30/189 (15%), Positives = 72/189 (38%), Gaps = 35/189 (18%)

		

		Query: 319 SGLIKQENLRMKKQVENVLNMSKLERNEMKLF-LRETNLRELIRNIANSVRLIVNERGGR 377

		             LI ++     K  E + ++S+L R  ++    R+ +L + +  + + ++L   +   R

		Sbjct: 183 RALILEDP---TKAREMLTSLSELMRYSLRYSNARQVSLADELTVVDSYLQLASIQFEDR 239

		

		Query: 378 LT--EDFKAERYNLKVDEFHLSNTLINLLDNANKY----SPDKPEIKIATRNEGNYYVIE 431

		           L           +++V        +  L++N  K+     P   +I +    +     +E

		Sbjct: 240 LQFENQINPAIMDVQVPPM----LVQTLVENGIKHGIAQLPQGGKILLKGTKDNGTVTLE 295

		

		Query: 432 ISDKGMGMEPQNKTKIFEKFFREETGNVHNVKGQGLGLSYVKKIIELHKG---QISVETQ 488

		           + + G       K                  +  G GL  V++ +++  G   QI +  +

		Sbjct: 296 VENTGSLALKNTK------------------ESTGTGLQNVRERLQMLYGTEAQIKLSEK 337

		

		Query: 489 KGKGSTFIV 497

		           +GK +  ++

		Sbjct: 338 QGKVNAMVL 346

		

		

		>HTHFIS#FIS bacterial regulatory protein HTH signature.

		          Length = 484

		

		 Score = 91.4 bits (227), Expect = 1e-23

		 Identities = 34/128 (26%), Positives = 64/128 (50%)

		

		Query: 4   RILLVEDDQSFGAVLKDYLSINNFEVTLATDGEEGLKEYTNNDFDICIFDVMMPKKDGFT 63

		            IL+ +DD +   VL   LS   ++V + ++     +     D D+ + DV+MP ++ F 

		Sbjct: 5   TILVADDDAAIRTVLNQALSRAGYDVRITSNAATLWRWIAAGDGDLVVTDVVMPDENAFD 64

		

		Query: 64  LAEDVKKLGKNIPIIFLTARNLREDILKGYQLGADDYITKPFDTELLLYKIKAILSRSTS 123

		           L   +KK   ++P++ ++A+N     +K  + GA DY+ KPFD   L+  I   L+    

		Sbjct: 65  LLPRIKKARPDLPVLVMSAQNTFMTAIKASEKGAYDYLPKPFDLTELIGIIGRALAEPKR 124

		

		Query: 124 LEEEEQEQ 131

		              + ++ 

		Sbjct: 125 RPSKLEDD 132

		

		

		>FLGPRINGFLGI#Flagellar P-ring protein signature.

		          Length = 373

		

		 Score = 28.7 bits (64), Expect = 0.040

		 Identities = 17/49 (34%), Positives = 21/49 (42%), Gaps = 6/49 (12%)

		

		Query: 26 ALQILCAVLLTDQEVRIKNIPDIQDV--NKLIGILGDLGVKVTKNGKGD 72

		          AL  L          RIK+I  +Q    N+LIG     G+ V   G GD

		Sbjct: 15 ALPFLSTPPAQADTSRIKDIASLQAGRDNQLIGY----GLVVGLQGTGD 59

		

		

		>RTXTOXIND#Gram-negative bacterial RTX secretion protein D

		           signature.

		          Length = 478

		

		 Score =  103 bits (259), Expect = 3e-26

		 Identities = 61/370 (16%), Positives = 128/370 (34%), Gaps = 56/370 (15%)

		

		Query: 21  WFFIGLGILLLLL--LLPWTQNIHTNGYV--SGLYQEQRPQSIQSPIPGKIIHWYVKNGD 76

		           +F +G  ++  +L  L         NG +  SG     R + I+      +    VK G+

		Sbjct: 62  YFIMGFLVIAFILSVLGQVEIVATANGKLTHSG-----RSKEIKPIENSIVKEIIVKEGE 116

		

		Query: 77  QVKKGDTLLRISEIKEDY------------------MDPLLVQRAEDQINAKDNVRDYYS 118

		            V+KGD LL+++ +  +                      L      +++       + Y 

		Sbjct: 117 SVRKGDVLLKLTALGAEADTLKTQSSLLQARLEQTRYQILSRSIELNKLPELKLPDEPYF 176

		

		Query: 119 AKI-----KTIGGQLDALNAARELKLNQIRIKLQQLNFKINATNAELQAANNEFRMAEDQ 173

		             +       +   +    +  + +  Q  + L +   +     A +    N  R+ + +

		Sbjct: 177 QNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTVLARINRYENLSRVEKSR 236

		

		Query: 174 YRRQEEMYKQGLVS---LTDFQRRNVSYQNALAKKNSIENKLAEAQQEILSLQVEQNATI 230

		                 +  +  ++   + + + + V   N L      +++L + + EILS + E     

		Sbjct: 237 LDDFSSLLHKQAIAKHAVLEQENKYVEAVNELR---VYKSQLEQIESEILSAKEEYQLVT 293

		

		Query: 231 QDYNEKISKLEGERFQSMGQVAGSDGEIAKLQTQVTNYKVRQGQYYIIATQDGQITQLSK 290

		           Q +  +I            ++  +   I  L  ++   + RQ    I A    ++ QL  

		Sbjct: 294 QLFKNEIL----------DKLRQTTDNIGLLTLELAKNEERQQASVIRAPVSVKVQQLKV 343

		

		Query: 291 TGIGEIIKEGENIGIIVPKSVKYAVEFYVSPVDLPLLQEGQKIRCTFDGFPAIVFSGWPN 350

		              G ++   E + +IVP+     V   V   D+  +  GQ      + F        P 

		Sbjct: 344 HTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAF--------PY 395

		

		Query: 351 SSYGTFPGKI 360

		           + YG   GK+

		Sbjct: 396 TRYGYLVGKV 405

		

		

		>ACRIFLAVINRP#Acriflavin resistance protein family signature.

		          Length = 1034

		

		 Score = 38.3 bits (89), Expect = 1e-04

		 Identities = 16/137 (11%), Positives = 45/137 (32%), Gaps = 25/137 (18%)

		

		Query: 37  IPLGIQAIISYAFGATMVTSIYLLIAFVVLGTWLTGYFQIKVMMIIEKIQQKIFVDYTFK 96

		           +P        + +G+  +     L +  + G    G      M ++E +  K+     + 

		Sbjct: 798 VPFSAFTTSHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASKLPAGIGYD 857

		

		Query: 97  IAKRLPDIDLYSVNNYHLPELINRFFDTQNLQKSFSKMLLSIPTSIIQIIFGVILLSLYH 156

		                                      +   + S ++    +  S + ++F + L +LY 

		Sbjct: 858 WT-----------------------GMSYQERLSGNQAPALVAISFV-VVF-LCLAALYE 892

		

		Query: 157 VWFLVFGIFLIIGIVVL 173

		            W +   + L++ + ++

		Sbjct: 893 SWSIPVSVMLVVPLGIV 909

		

		

		>ALARACEMASE#Alanine racemase signature.

		          Length = 356

		

		 Score =  301 bits (772), Expect = 2e-97

		 Identities = 90/372 (24%), Positives = 165/372 (44%), Gaps = 25/372 (6%)

		

		Query: 449 KHDTVLEVNLNNLLHNINVHKSLLKPETKIMAMVKAYSYGLGGYEIAEFLQHHHIDYLGV 508

		                  ++L  L  N+++ +       ++ ++VKA +YG G   I   +     D   +

		Sbjct: 2   TRPIQASLDLQALKQNLSIVRQAA-THARVWSVVKANAYGHGIERIWSAIGA--TDGFAL 58

		

		Query: 509 AVADEGVELRKNGITVPIVVMNPEQHS--YNTIIEYNLEPNIYSFRVLELFHKQLKQNGY 566

		              +E + LR+ G   PI+++    H+       ++ L   ++S   L+       +   

		Sbjct: 59  LNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQHRLTTCVHSNWQLKALQNARLKA-- 116

		

		Query: 567 EGRYPIHIKLETGMHRLGFKEDEIDQLKDYLNQMS-VKVESIFSHLSSSDIPQEKDYTLA 625

		                I++K+ +GM+RLGF+ D +  +   L  M+ V   ++ SH + ++     D    

		Sbjct: 117 --PLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHFAEAE---HPDGISG 171

		

		Query: 626 QCQKFDKLSQNIIKDLNYKPLRHILNSAGITNYTYYQMDMVRIGIGMMGISASPEIQPL- 684

		              +     +   + L  +  R + NSA    +     D VR GI + G S S + + + 

		Sbjct: 172 AMARI----EQAAEGLECR--RSLSNSAATLWHPEAHFDWVRPGIILYGASPSGQWRDIA 225

		

		Query: 685 ---LNPVVAFKSVISQISEIQPNDSVSYGRRYKASKSTRIATIPVGYADGVPRLLSNGVG 741

		              L PV+   S I  +  ++  + V YG RY A    RI  +  GYADG PR    G  

		Sbjct: 226 NTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGYPRHAPTG-T 284

		

		Query: 742 YVGIKNTLCPIVGSVCMDMMMVDISDLP-TKEGDEVTIFHEKPSLEDFAMYSQTIPYEVL 800

		            V +       VG+V MDM+ VD++  P    G  V ++ ++  ++D A  + T+ YE++

		Sbjct: 285 PVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAAAAGTVGYELM 344

		

		Query: 801 TSISRRVKRVYI 812

		            +++ RV  V +

		Sbjct: 345 CALALRVPVVTV 356

		

		

		>DHBDHDRGNASE#2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase

		           signature.

		          Length = 261

		

		 Score =  161 bits (408), Expect = 5e-51

		 Identities = 93/251 (37%), Positives = 139/251 (55%), Gaps = 10/251 (3%)

		

		Query: 4   LEGKVALITGATRGIGKGIAEIFAAQGAQVAFTYAGSVDKAQALEAELNKTTKAKAYQSD 63

		           +EGK+A ITGA +GIG+ +A   A+QGA +A          + + +   +   A+A+ +D

		Sbjct: 6   IEGKIAFITGAAQGIGEAVARTLASQGAHIAAVDYNPEKLEKVVSSLKAEARHAEAFPAD 65

		

		Query: 64  ASDYEGSQKLVEEVLAEFGKIDILVNNAGITKDNLMLRMSKEDWDTIIKVNLDSVFNLTK 123

		             D     ++   +  E G IDILVN AG+ +  L+  +S E+W+    VN   VFN ++

		Sbjct: 66  VRDSAAIDEITARIEREMGPIDILVNVAGVLRPGLIHSLSDEEWEATFSVNSTGVFNASR 125

		

		Query: 124 AVIKPMMKARGGSIINMTSVVGIKGNAGQANYAASKAGVIGFTKSIALELGSRNIRCNAI 183

		           +V K MM  R GSI+ + S          A YA+SKA  + FTK + LEL   NIRCN +

		Sbjct: 126 SVSKYMMDRRSGSIVTVGSNPAGVPRTSMAAYASSKAAAVMFTKCLGLELAEYNIRCNIV 185

		

		Query: 184 APGFIETEMTAAL------DEKTVQGWRET----IPLKRGGQPEDVANACVFLGSELSSY 233

		           +PG  ET+M  +L       E+ ++G  ET    IPLK+  +P D+A+A +FL S  + +

		Sbjct: 186 SPGSTETDMQWSLWADENGAEQVIKGSLETFKTGIPLKKLAKPSDIADAVLFLVSGQAGH 245

		

		Query: 234 VTGQVLNVDGG 244

		           +T   L VDGG

		Sbjct: 246 ITMHNLCVDGG 256

		

		

		>NUCEPIMERASE#Nucleotide sugar epimerase signature.

		          Length = 334

		

		 Score =  373 bits (959), Expect = e-131

		 Identities = 128/351 (36%), Positives = 192/351 (54%), Gaps = 37/351 (10%)

		

		Query: 5   TYLVTGGSGFIGSHLVEALLKNGHFVINVDNFDDFYNYKTKINNTLESLGITTNFDFENK 64

		            YLVTG +GFIG H+ + LL+ GH V+ +DN +D+Y+   K    LE L           

		Sbjct: 2   KYLVTGAAGFIGFHVSKRLLEAGHQVVGIDNLNDYYDVSLK-QARLELLA---------- 50

		

		Query: 65  NLDIKKLASLVNKGNYKFYYQDIRDKEGLEKIFKNHRPDVVIHLAALAGVRPSIERPLEY 124

		                       +  ++F+  D+ D+EG+  +F +   + V        VR S+E P  Y

		Sbjct: 51  ------------QPGFQFHKIDLADREGMTDLFASGHFERVFISPHRLAVRYSLENPHAY 98

		

		Query: 125 QEVNIKGTMNIWEVAKDLGICKFVIASSSSVYGNNEKIPFSEEDNVDRPISPYAATKKCV 184

		            + N+ G +NI E  +   I   + ASSSSVYG N K+PFS +D+VD P+S YAATKK  

		Sbjct: 99  ADSNLTGFLNILEGCRHNKIQHLLYASSSSVYGLNRKMPFSTDDSVDHPVSLYAATKKAN 158

		

		Query: 185 EVLGHTYHHLYGMDMVQLRFFTVYGPRQRPDLAIHKFAKIIKDNKQVPFYGDGNTARDYT 244

		           E++ HTY HLYG+    LRFFTVYGP  RPD+A+ KF K + + K +  Y  G   RD+T

		Sbjct: 159 ELMAHTYSHLYGLPATGLRFFTVYGPWGRPDMALFKFTKAMLEGKSIDVYNYGKMKRDFT 218

		

		Query: 245 FVDDIIDGIMKSIKYVEE--------------NAGVYEIFNLGESEVIPLHKMLSTIEEE 290

		           ++DDI + I++    +                +   Y ++N+G S  + L   +  +E+ 

		Sbjct: 219 YIDDIAEAIIRLQDVIPHADTQWTVETGTPAASIAPYRVYNIGNSSPVELMDYIQALEDA 278

		

		Query: 291 LGVKATLNKLPMQAGDVQKTNADIRKAQQKIGYAPTTNFQNGIKKFVEWFL 341

		           LG++A  N LP+Q GDV +T+AD +   + IG+ P T  ++G+K FV W+ 

		Sbjct: 279 LGIEAKKNMLPLQPGDVLETSADTKALYEVIGFTPETTVKDGVKNFVNWYR 329

		

		

		>SECA#SecA protein signature.

		          Length = 901

		

		 Score =  860 bits (2223), Expect = 0.0

		 Identities = 392/1051 (37%), Positives = 537/1051 (51%), Gaps = 254/1051 (24%)

		

		Query: 4    LNTILKSFLGNKNEKDLKEVKKVVAKIKAVEPEVGKLSDDGLRQKTEEFQNKIKEATSKI 63

		            L  +L    G++N++ L+ ++KVV  I A+EPE+ KLSD+ L+ KT EF+ ++++     

		Sbjct: 2    LIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELKGKTAEFRARLEKGEV-- 59

		

		Query: 64   TSQVEELKEKIKTSKDVDEKEALFNKIEELKKEAYQIEEKVLTDILPEAFAVLKETARRW 123

		                                                     L +++PEAFAV++E ++R 

		Sbjct: 60   -----------------------------------------LENLIPEAFAVVREASKR- 77

		

		Query: 124  AQNGEIRVKANDRDRALAATKDFVVIEGDEAVWLNHWDAAGTKVQWDMVHYDVQFIGGVV 183

		                                                         + M H+DVQ +GG+V

		Sbjct: 78   --------------------------------------------VFGMRHFDVQLLGGMV 93

		

		Query: 184  LHGGKIAEMATGEGKTLVGTLPIYLNALPGRGVHVVTVNDYLARRDSAWMGPLYEFHGLS 243

		            L+   IAEM TGEGKTL  TLP YLNAL G+GVHVVTVNDYLA+RD+    PL+EF GL+

		Sbjct: 94   LNERCIAEMRTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLT 153

		

		Query: 244  IDCIDNHQPNSDARRKAYQCNITYGTNNEFGFDYLRDNMVNSPNEMVQGELNYAIVDEVD 303

		            +       P + A+R+AY  +ITYGTNNE+GFDYLRDNM  SP E VQ +L+YA+VDEVD

		Sbjct: 154  VGINLPGMP-APAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVD 212

		

		Query: 304  SVLIDDARTPLIISGPVPQGDRQEFDVLKPSVDRIVDVQKKTVSAIFHEAKKLIAQGNTK 363

		            S+LID+ARTPLIISGP                        +  S ++    K+I      

		Sbjct: 213  SILIDEARTPLIISGPA-----------------------EDSSEMYKRVNKIIP----- 244

		

		Query: 364  EGGFKLLQAYRGLPKNRQLIKFLSETGNKALLQKVEAQYMQDNNREMPKVDKDLYFVIDE 423

		                                                    +  + E  + +    F +DE

		Sbjct: 245  -----------------------------------HLIRQEKEDSETFQGEGH--FSVDE 267

		

		Query: 424  KNNQIDLTDKGVEYMSQGNSDPNFFVLQDIGTELAELEAQNLPKEEEFAKKEELFRDFAV 483

		            K+ Q++LT++G+  + +         + D G  L       L                  

		Sbjct: 268  KSRQVNLTERGLVLIEELLVKEG---IMDEGESLYSPANIML------------------ 306

		

		Query: 484  KSERIHTLNQLLKAYTLFEKDDQYVVMDGEVKIVDEQTGRIMEGRRYSDGLHQAIEAKEN 543

		                +H +   L+A+ LF +D  Y+V DGEV IVDE TGR M+GRR+SDGLHQA+EAKE 

		Sbjct: 307  ----MHHVTAALRAHALFTRDVDYIVKDGEVIIVDEHTGRTMQGRRWSDGLHQAVEAKEG 362

		

		Query: 544  VKIEAATQTFATITLQNYFRMYNKLAGMTGTAETESGEFWEIYRLDVVVIPTNRPIQRND 603

		            V+I+   QT A+IT QNYFR+Y KLAGMTGTA+TE+ EF  IY+LD VV+PTNRP+ R D

		Sbjct: 363  VQIQNENQTLASITFQNYFRLYEKLAGMTGTADTEAFEFSSIYKLDTVVVPTNRPMIRKD 422

		

		Query: 604  KHDLVYKTNREKYNAVIEEVEKLTSAGRPVLVGTTSVEISQLLSKALQLRKIPHQVLNAK 663

		              DLVY T  EK  A+IE++++ T+ G+PVLVGT S+E S+L+S  L    I H VLNAK

		Sbjct: 423  LPDLVYMTEAEKIQAIIEDIKERTAKGQPVLVGTISIEKSELVSNELTKAGIKHNVLNAK 482

		

		Query: 664  LHKKEAEIVAEAGRAGVVTIATNMAGRGTDIKL--------------------------- 696

		             H  EA IVA+AG    VTIATNMAGRGTDI L                           

		Sbjct: 483  FHANEAAIVAQAGYPAAVTIATNMAGRGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQ 542

		

		Query: 697  --SKEVKDAGGLAIIGTERHDSRRVDRQLRGRAGRQGDPGSSQFYVSLEDNLMRLFGSER 754

		                 V +AGGL IIGTERH+SRR+D QLRGR+GRQGD GSS+FY+S+ED LMR+F S+R

		Sbjct: 543  VRHDAVLEAGGLHIIGTERHESRRIDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDR 602

		

		Query: 755  IAKMMDRLGHKEGEVIQHSMITKSIERAQKKVEENNFGIRKRLLEYDDVMNKQRDVIYKR 814

		            ++ MM +LG K GE I+H  +TK+I  AQ+KVE  NF IRK+LLEYDDV N QR  IY +

		Sbjct: 603  VSGMMRKLGMKPGEAIEHPWVTKAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQ 662

		

		Query: 815  RKNALFGDHLKYDIANMIFDVSHSIVNQTKMHGDYKDFEFEVIKYFTMEAPVSEADFKNK 874

		            R   L    +   I ++  DV  + ++        +    E+     ++  +      + 

		Sbjct: 663  RNELLDVSDVSETINSIREDVFKATIDAYIPPQSLE----EMWDIPGLQERLKNDFDLDL 718

		

		Query: 875  TVKELTDVVFKKAQEDYEMKLNLLKEKSFPIIENVYQNQGNMFKMIQVPFSDGTKTMTIL 934

		             + E  D       ++ E+    L+E+                               IL

		Sbjct: 719  PIAEWLD-------KEPELHEETLRER-------------------------------IL 740

		

		Query: 935  ADLKEAYETQCDSL----INDFEKNICLSIIDENWKLHLREMDDLRRSSQGAVYEQKDPL 990

		            A   E Y+ + + +    +  FEK + L  +D  WK HL  MD LR+      Y QKDP 

		Sbjct: 741  AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKDPK 800

		

		Query: 991  VIYKQESFHLFSEMVDKINKEIISFLYKGEI 1021

		              YK+ESF +F+ M++ +  E+IS L K ++

		Sbjct: 801  QEYKRESFSMFAAMLESLKYEVISTLSKVQV 831

		

		

		>INTIMIN#Intimin signature.

		          Length = 939

		

		 Score = 27.0 bits (59), Expect = 0.022

		 Identities = 15/69 (21%), Positives = 23/69 (33%), Gaps = 7/69 (10%)

		

		Query: 56  HHSHFSTQKHYKSFFSASYFVLPKLVNIPSLLKHKR-------EKKIADYRKWQIVKYTF 108

		           +   +S Q  Y+     S  + P+ VN    L   R          I +Y+K  I+    

		Sbjct: 399 NDLLYSMQFRYQFDKPWSQQIEPQYVNELRTLSGSRYDLVQRNNNIILEYKKQDILSLNI 458

		

		Query: 109 THSNRGPPH 117

		            H   G   

		Sbjct: 459 PHDINGTER 467