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Submitter
May 22, 2025 at 11:00 AM EDT (USA)

Register for Creative Biolabs' Webinar: https://www.creativebiolabs.net/generation-of-a-dual-function-multi-engager-antibody-for-simultaneous-targeting-nk-cells-and-tumor-cells.htm

The relentless pursuit of innovative cancer immunotherapies has unveiled natural killer (NK) cells as formidable agents in the fight against malignancies. While these innate immune cells possess inherent tumor-killing capabilities, their full potential remains constrained by regulatory mechanisms and tumor evasion strategies. At the forefront of this research stands ADAM17, a membrane-associated protease that functions as both a negative regulatory checkpoint in NK cells and a tumor-associated antigen overexpressed in various malignancies. Creative Biolabs is honored to invite Dr. Bruce Walcheck to introduce the Targeted ADAM17 Blocker and Killer (TABK), an ingenious multi-engager antibody complex that simultaneously enhances NK cell proliferation while directing these empowered immune cells to engage and eliminate ADAM17-expressing tumor cells. Join us to explore how this innovative approach leverages ADAM17's unique dual role to create a potent immunotherapeutic strategy with promising implications for cancer treatment.

During this webinar, we will discuss the following key points:
  • NK cell-mediated natural cytotoxicity and antibody-dependent cellular cytotoxicity (ADCC)
  • Utilizing NK cells to kill cancer cells
  • ADAM17, a membrane-associated protease expressed by NK cells
  • ADAM17 functions as a negative regulatory checkpoint in NK cells and is a tumor-associated antigen
  • ADAM17 inhibition by the mAb Medi-1 enhances NK cells activation and proliferation
  • Development of the multi-engager antibody complex Targeted ADAM17 Blocker and Killer (TABK)
  • TABK selectively blocks ADAM17 in NK cells and synergizes with IL-15 stimulation to enhance NK cell activation and proliferation
  • TABK engages ADAM17 overexpressed by various malignancies, linking NK cells to tumor cells to mediate their killing
Education: Creative BioMart Scholarship Program 2025
Submitted by Caroline Green; posted on Tuesday, April 29, 2025

To further support the research and higher education of young and ambitious talent in the biomedical and scientific fields, Creative BioMart is proud to announce the 2025 Scholarship Program, which will award $1,000 to an outstanding college student.

Thanks for your interest in the 2025 Creative BioMart Scholarship Program!

REQUIREMENTS

The Creative BioMart scholarship is open on a global basis. To be eligible to receive a scholarship, you must meet the following requirements:
  • Enrolled as an undergraduate, graduate or Ph.D. student at an accredited college, university or research Institute.
  • Major in Biology, Biochemistry, Molecular Biology, Biotechnology or a related major.
  • Can provide proof of a good average grade with at least a B (GPA 3.0/4.0).

EVALUATION CRITERIA

The Creative BioMart selection committee will review each application fairly and carefully according to the following criteria:
  • Academic Ability: In addition to grade point average, your project, Bachelor's/Master's thesis, internship experience, or detailed learning plan will be considered.
  • Leadership Skills: The ability to organize and positively influence others inside and outside of school.
  • Social Concerns: Purposeful and meaningful participation in volunteer activities, community service or other public service activities.

FOR MORE INFORMATION

More at https://www.creativebiomart.net/creative-biomart-scholarship-program.htm
Submitter
August 10-12, 2025
Columbus, OH, USA
https://icibm2025.iaibm.org

We are pleased to announce the 13th International Conference on Intelligent Biology and Medicine (ICIBM 2025).

ICIBM is a high-caliber conference that brings together eminent scholars and experts from various fields of computational biology, bioinformatics, genomics, data science, AI, biomedical informatics, and related experimental research. The purpose of the ICIBM is to provide a congenial atmosphere highly conducive to extensive discussion, collaboration, and networking. For full conference details, please visit the official website: https://icibm2025.iaibm.org.

CALL FOR PAPERS

We invite you to submit papers and abstracts with unpublished, original work describing recent advances in all aspects of these topics, including but not limited to, the following specific topics:

Bioinformatics:
  • Genomics and genetics/epigenetics, including integrative & functional genomics, genome evolution, GWAS.
  • Next-generation sequencing data analysis, 3D genome.
  • Single-cell omics, spatial transcriptomics, and the related technologies
  • Big data science including storage, analysis, modeling, visualization, and cloud.
  • Precision medicine, translational bioinformatics, and medical informatics.
  • Drug discovery, design, and re-purposing.
  • Proteomics, and protein structure prediction, function, and interactions.
  • Microbiome and Metagenomics.
Data Science and AI:
  • Artificial intelligence, machine learning, deep learning, data mining, knowledge discovery.
  • Large language model, foundation model, and computer vision in biomedical fields.
  • GPT prompt tools and related applications in biological and biomedical informatics
  • Natural language processing, literature mining, semantic ontology, and health informatics.
  • Neural computing, kernel methods, feature selection/extraction.
  • Evolutionary computing, swarm intelligence / optimization, ensemble methods.
  • Artificial life and artificial immune system.
  • Biomedical image analysis and processing.
Systems Biology:
  • Modeling and simulation of biological processes, pathways, networks, and interactomes.
  • Modeling of cellular and multi-cellular interaction systems.
  • Multi-dimensional omics data integration.
  • Synthetic biological systems.
  • Metabolomics, microbiome, and lipidomics.
  • Self-organization in living systems (cells, organisms, swarms, ecosystems, etc.).
Medical Informatics:
  • Cohort discovery, EHR-based phenotyping, predictive modeling.
  • Data quality assessment or validation.
  • Clinical decision support solutions.
  • Informatics to address disparities in health and health care.
  • Interoperability (e.g., ontology, terminology, standards, and others).
  • Machine learning for clinical applications, genome, and phenome analysis/associations.
  • Mobile health and wearable devices.
  • Human-computer interaction and human factors
Paper Submission and Publication:

Prospective authors are invited to submit unpublished work to ICIBM 2025. Selected papers of registered authors will be recommended for publication in special issues of journals in bioinformatics, data science, quantitative science, and biomedical informatics, by following the previous ICIBM conferences.

Abstract Submission:

Conference participants are invited to submit abstracts formatted using the abstract template available on the conference website. Abstracts should be no more than 400 words. We also welcome highlight papers that have been recently published or accepted for publication. These abstracts should include a complete reference to the published work.
All submissions will be evaluated by a group of experts for selection as oral presentations or posters.

IMPORTANT DATES

Deadline for Paper Submission: March 17, 2025
Notification to Authors: May 16, 2025
Early Registration Opens: June 1, 2025
Abstract Submission Deadline: June 20, 2025
Early Registration Deadline: July 18, 2025
Regular Registration Opens: July 19, 2025
Conference Dates: August 10-12, 2025

Sincerely,
On behalf of ICIBM Organizing Committee
Lang Li, Qin Ma, Lianbo Yu and Maciej Pietrzak
Submitter
I've written a new guide:

How to find the structure of a protein: https://proteopedia.org/w/How_to_find_the_structure_of_a_protein. Its suitable for students. It starts by finding the amino acid sequence in UniProt, and suggests what to consider when selecting the best model when multiple empirical models are available. And when no empirical model is available, it directs you to ...

How to predict structures with AlphaFold using the newest AlphaFold3 Server (with a few tips to avoid frustration): https://proteopedia.org/w/How_to_predict_structures_with_AlphaFold

There is also a new guide about how to be aware of Missing Residues and Incomplete Sidechains: https://proteopedia.org/w/Missing_residues_and_incomplete_sidechains. It illustrates how you can't be unaware of them in FirstGlance in Jmol, but you may well be unaware in MolStar, PyMOL, ChimeraX, or iCn3D. Then it suggests how to use AlphaFold models to fill in missing sidechain atoms or loops, so that your analysis of charge distribution is not erroneous.

Filling in missing charged atoms on the protein surface is especially important before you make an Electrostatic Potential Map, which you can do quite easily in several popular free applications: https://proteopedia.org/w/Electrostatic_potential_maps. That new page illustrates maps made in each application.

~ Eric Martz http://martz.molviz.org
Submitter
November 26, 2024
19:30 hrs IST (0900 hrs ET)

At The Forefront of Genomics: Making Genomic Medicine a Reality
Eric Green, MD, PhD
Director, NHGRI, USA

Moderated by: Prashanth N Suravajhala, PhD and Gyaneshwer Chaubey, PhD

One-click registration at https://bioclues.org/events
Submitter
"Body roundness index (BRI) might be a more accurate measurement than body mass index (BMI) for predicting weight-related health risks."

Source: https://www.health.harvard.edu/staying-healthy/body-roundness-may-beat-body-mass-for-identifying-risky-fat

Journal article: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2819558
Submitter
March 19, 2025 (online event)
March 20-21, 2025 (in Florence, Italy)
http://conference.pixel-online.net/NPSE/callforpapers.php

The event brings together teachers, researchers, practitioners and project managers from all over the world to share findings, expertise and experience about innovative science teaching and learning methodologies.

Onsite participants are welcome in Florence for two full days of thought-provoking sessions, integrated by endless networking opportunities and social events.

Online participants can contribute with asynchronous or synchronous online presentations. The latter will be delivered on 19 March via the Conference Virtual Platform.

During the Conference:
  • All accepted papers will be presented onsite and online.
  • Questions and Answers sessions will follow each paper presentation.
  • Poster presentation sessions will be held onsite and online.
  • Networking opportunities will be organized.

IMPORTANT DATES

Abstracts submission deadline: October 9, 2024
Papers submission (possibility to extend): January 22, 2025
Conference day of the ONLINE EVENT: March 19, 2025
Conference days of the ONSITE EVENT IN FLORENCE: March 20-21, 2025

All accepted papers will be included in the Conference Proceedings e-book published with ISBN, ISSN and DOI codes. The publication will be sent to be reviewed for inclusion Web of Science and SCOPUS. The publication will also be included in Academia.edu and indexed in Google Scholar.

FOR MORE INFORMATION

Contact: science[at]pixel-online.net
Video: https://youtu.be/EtINTHNZyjE
Submitter
Creative Biolabs, a leading CRO, is proud to announce the opening of applications for its 2024 scholarship program. This initiative aims to provide financial assistance to students within the biotechnology industry, supporting their academic pursuits and research endeavors.

The Creative Biolabs Scholarship Program reflects the company's commitment to nurturing the next generation of biotech talent. As a renowned provider of biopharmaceutical development solutions, Creative Biolabs recognizes the importance of investing in the education and advancement of young scientists and researchers.

"We are excited to launch our 2024 scholarship program, which underscores our dedication to fostering innovation and excellence in the field of biotechnology," according to a scientist at Creative Biolabs. "Through this initiative, we aim to empower students to pursue their academic and professional aspirations, ultimately contributing to the advancement of the biotech industry."

The scholarship program opens to undergraduate, graduate, and doctoral students pursuing studies in science-related fields, with a focus on areas such as immunology, biochemistry, and molecular biology, which play a crucial role in the development of novel biopharmaceuticals and are key areas of focus for Creative Biolabs. Applicants will be evaluated based on academic merit, research achievements, leadership potential, and a personal statement outlining their career goals and aspirations in biotechnology.

"In addition to financial support, the recipients of the Creative Biolabs Scholarship have the chance to learn more about the exclusive resources and networking opportunities within the biotech community. This includes access to Creative Biolabs' cutting-edge technologies and platforms, such as high-throughput hybridoma generation, B cell sorting, and de novo antibody sequencing." The scientist elaborated.

High-Throughput Hybridoma Generation:

One of the key technologies offered by Creative Biolabs is the powerful Hyperdoma™, by far the most comprehensive and advanced hybridoma generation and screening platform, incorporating high-throughput screening systems like ClonePix 2, FMAT, and Celigo Image Cytometer. It fully takes advantage of the hybridoma machinery to sift out the best antibodies for any possible research, and meanwhile, its electrofusion and advanced screening approaches generate an expanded positive clone pool to largely maximize the possibility of producing the most viable clone, essential for the production of monoclonal antibodies. Utilizing this technology, researchers can significantly accelerate the process of antibody development and maximize their research efficiency.

De Novo Antibody Sequencing:

Another important solution is de novo antibody sequencing, which achieves 100% accuracy in interpreting antibody sequences and covers V, J, and C gene segments, the CDR3 region, fluorochrome mAbs and non-standard antibodies, and isobaric amino acids.

"Our scholarship recipients will have the opportunity to engage with industry-leading experts and learn more about state-of-the-art technologies like those above to further their research endeavors," said the scientist. "We believe that by investing in the education and development of talented students, we can drive innovation and advance the frontiers of biotechnology."

Interested students can find more information and apply for the scholarship program at https://www.creative-biolabs.com/scholarship-program.html.

ABOUT US

Creative Biolabs, specializing in biopharmaceutical development, offers a range of antibody discovery services. With a focus on nurturing talent, Creative Biolabs annually provides scholarships to biotech students, reflecting its dedication to education and innovation.
Resources: Prediction of Toxicity of Peptides
Submitted by Gajendra P.S. Raghava; posted on Thursday, July 25, 2024
Submitter
We are happy to announce updated version of our popular web server ToxinPred, which is developed for predicting for predicting toxicity of peptides. This will be useful for researchers who's working on peptide-based drug discovery.

URL: http://webs.iiitd.edu.in/raghava/toxinpred3/
Paper Link: https://www.sciencedirect.com/science/article/pii/S0010482524010114?dgcid=author
Education: Creative BioMart Scholarship Program 2024
Submitted by Caroline Green; posted on Thursday, July 25, 2024

As a leading supplier of a wide range of biological products including recombinant proteins, native proteins, cell/tissue lysates, etc. and a high-quality custom service provider specializing in academic research, diagnostic and therapeutic applications as well as industry requirements, Creative BioMart always strives to support young and ambitious talents in our field.

To further support their research and higher education in the biomedical and science fields, Creative BioMart is proud to announce the 2024 Scholarship Program, which will award $1,000 to an outstanding college student.

Thanks for your interest in the 2024 Creative BioMart Scholarship Program!

REQUIREMENTS

The Creative BioMart scholarship is open on a global basis. To be eligible to receive a scholarship, you must meet the following requirements:
  • Enrolled as an undergraduate, graduate or Ph.D. student at an accredited college, university or research Institute.
  • Major in Biology, Biochemistry, Molecular Biology, Biotechnology or a related major.
  • Can provide proof of a good average grade with at least a B (GPA 3.0/4.0).

EVALUATION CRITERIA

The Creative BioMart selection committee will review each application fairly and carefully according to the following criteria:

Academic ability: In addition to grade point average, your project, Bachelor's/Master's thesis, internship experience, or detailed learning plan will be considered.
Leadership skills: The ability to organize and positively influence others inside and outside of school.
Social concerns: Purposeful and meaningful participation in volunteer activities, community service or other public service activities.

FOR MORE INFORMATION

More at https://www.creativebiomart.net/creative-biomart-scholarship-program-2024.htm
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