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    Research: UC Davis: Dark centers of chromosomes reveal ancient DNA
    Submitted by J.W. Bizzaro; posted on Thursday, June 20, 2019



    In chromosome 11, they found highly diverged haplotypes of Neanderthal DNA in non-African genomes. These haplotypes diverged between 700,000 to a million years ago, around the time the ancestors of Neanderthals split from other human ancestors. The centromere of chromosome 12 also contains an even more ancient, archaic haplotype that appears to be derived from an unknown relative.



    French pharmaceutical firm Sanofi said Tuesday it is partnering with Google to use artificial intelligence and deep analytics tools to sift through its data to find better treatments.

    The titan in online search "will apply technology and analytics on Sanofi's large real world database to better understand what treatments work for patients," the pharmaceutical firm said in a statement.

    July 19, 2019
    The Residency Towers, Chennai, India[...]y4-5y

    We invite you to attend the session and participate in the discussions. It's an interactive session with understanding and impact.

    Please register by clicking on the online registration link:

    We look forward to your participation.


    July 1 – August 9, 2019
    Louisiana State University, Baton Rouge[...]gram/

    Louisiana Biomedical Research Network is announcing its second summer bioinformatics training program hosted by the Louisiana State University Center for Computation and technology. The program will be conducted by faculty from the LBRN network and supported by Pine Biotech, a Louisiana-based bioinformatics technology company that specializes in interactive, user-friendly technology for researchers and clinicians. In this program, a novice or experienced user will be able to learn about and independently conduct basic RNA-seq analysis, including:
    • Mapping of reads on reference genomes
    • Quantification of expression and identification of alternative splicing
    • Exploration of expression data using differential gene expression or data mining techniques
    • Annotation of analysis results using reference databases



    The Association for Molecular Pathology (AMP), the premier global, molecular diagnostic professional society, expressed serious concerns with Congress' recent proposal to amend Section 101 of the Patent Act. If enacted, the draft legislation would overturn 150 years of patent case law and permit patenting of human genes and naturally-occurring associations between genes and diseases. In a recent letter to Senators Coons and Tillis, and Representatives Collins, Johnson and Stivers, AMP joined a diverse community of 169 medical, scientific, patient advocacy, women's health, and civil rights organizations, opposing the recent proposal.
    Source:[...]9.pdf (PDF)

    Letter:[...]r.pdf (PDF)
    Education: Training in genomics workflows for computational novices
    Submitted by Erin Becker; posted on Monday, June 03, 2019

    Wish your lab team could level-up their computational skills for working with sequencing data? Data Carpentry ( provides training to get your team away from messy spreadsheets to writing their own custom Bash scripts and computing in the cloud. Our volunteer Instructors are graduate students, postdocs, and other active genomics research professionals who are trained in real-time instruction to customise their teaching to your audience. Instructors build on their audience's existing knowledge to enable them to quickly apply skills learned to their own research.

    We deliver a consistent, high-quality learning experience. Our lessons have been taught over 1000 times and are continuously improved and updated by our community. We create a friendly environment for learning to empower researchers – 91% of our learners recommend our workshops, and 78% stably integrate the tools we teach into their own work.

    We provide comprehensive event handling, from registration through assessment. As a community of volunteers, our workshop fee is highly competitive, covering our administrative costs and core operations. With over 1600 Instructors in 50 countries, we work to find local instructors to minimise costs to you.

    Learn more ([...]oad=1) (PDF) or book a workshop ( today.

    Data Carpentry is a lesson program within The Carpentries ( – a fiscally sponsored project of Community Initiatives (, a registered 501(c)3 non-profit. The Carpentries builds global capacity in essential data and computational skills for conducting efficient, open, and reproducible research. We train and foster an active, inclusive, diverse community of learners and instructors that promotes and models the importance of software and data in research. We collaboratively develop openly-available lessons and deliver these lessons using evidence-based teaching practices. We focus on people conducting and supporting research.


    June 10 - August 30, 2019
    Online program

    Precision medicine is changing the way we understand, diagnose and treat cancer. The transformation is driven by high-throughput molecular data from patients, animal models, and large-scale experiments. In this program, we will explore how the various -omics data types can be analyzed to understand the basic biology associated with cancer onset, development, and outcomes and see how large-scale clinical trials and experiments provide an opportunity to improve precision oncology.

    openbiox is a community-driven global bioinformatics innovation collaboration group. It was founded in March 2019 and consist of undergraduate, master, doctoral, and postdoctoral students from well-known universities and research institutes around the world.

    As of April 2019, openbiox had a total of 69 members, completed the formation of at least 11 project teams, and launched more than 10 bioinformatics innovation practice projects.

    Welcome all the friends who are interested in bioinformatics to join us.

    Purpose: Inventing, Optimizing, Sharing

    1. Find like-minded friends.
    2. Startup bioinformatics projects.
    3. Collaborate on the bioinformatics projects.
    4. Sharing resources and ideas.
    5. Get sponsorship.




    The global search for a group A streptococcal (Strep A) vaccine has narrowed after researchers identified a common gene signature in almost all global Strep A strains by sequencing thousands of genomes in a project spanning 10 years and more than 20 countries.



    Using artificial intelligence, a Princeton University-led team has decoded the functional impact of such mutations in people with autism. The researchers believe this powerful method is generally applicable to discovering such genetic contributions to any disease.

    Publishing May 27 in the journal Nature Genetics, the researchers analyzed the genomes of 1,790 families in which one child has autism spectrum disorder but other members do not. The method sorted among 120,000 mutations to find those that affect the behavior of genes in people with autism. Although the results do not reveal exact causes of cases of autism, they reveal thousands of possible contributors for researchers to study.
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