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    BACKGROUND

    About the role:
    Dr Claus Jorgensen, Group Leader of the Systems Oncology Group, is looking for a computational Postdoctoral Scientist to join his group. This is a great opportunity for a self-motivated, innovative, meticulous and organised candidate with excellent communication skills to work in a dynamic laboratory undertaking cutting edge research.

    The goal of the Systems Oncology Group is to understand how aberrations in cellular signalling affect tumour progression. In particular, we are interested in understanding how signalling between cancer cells and cells in the tumour microenvironment promote tumour progression and drug resistance. Using global approaches such as proteomics, mass cytometry, CRISPR and RNA sequencing we aim to identify and understand the mechanisms of cell-cell communication (Tape et al Cell 2016, Jorgensen et al Science 2009, Tape et al Mol Cell Proteomics 2014, Tape et al Anal Chem 2014, Worboys et al Nature Methods 2014). This role is an exciting opportunity to join a multidisciplinary team to study these problems.

    RESPONSIBILITIES

    This position is part of an ERC consolidator award to understand the evolutionary constraints of the tumour microenvironment on pancreatic cancer progression. Specifically, you will develop an independent research project to interrogate cellular interactions in the tumour microenvironment and help identify key regulatory events that drive clonal selection. Using computational analysis of available and newly generated data (proteomics, single cell analysis) you will develop a framework to associate changes in tumour and stromal departments and to develop experimental testable hypotheses. You will be experienced in computational biology/bioinformatics, analysis of quantitative signalling data and expression data.

    REQUIREMENTS

    About you:
    You should have a PhD in systems biology, engineering, computational biology or a relevant field. Experience in computational modelling, data integration and analysis is essential to the success of the project. Key qualities should include independent thinking, ability to work in a team and good communication skills, all of which are needed to efficiently work in a multidisciplinary team.

    Why choose Cancer Research UK Manchester Institute?
    The Cancer Research UK Manchester Institute (www.cruk.manchester.ac.uk), an Institute of The University of Manchester (www.manchester.ac.uk), is a world-leading centre for excellence in cancer research. The Institute is core funded by Cancer Research UK (www.cancerresearchuk.org), the largest independent cancer research organisation in the world. We are currently situated at the internationally renowned life sciences campus at Alderley Park in Cheshire England, 15 miles from Manchester, a vibrant and dynamic city surrounded by beautiful countryside.

    We are partnered with The Christie NHS Foundation Trust (adjacent to the CRUK Manchester Institute, Paterson Building) in South Manchester (www.christie.nhs.uk), one of the largest cancer treatment centres in Europe. These factors combine to provide an exceptional environment in which to pursue basic, translational and clinical research programmes.

    TERMS

    Duration: Fixed term for 3 years

    COMPENSATION

    Salary starting: £31,604 – £41,929 per annum (depending on qualifications and experience)

    HOW TO APPLY

    To apply for this position please visit our website: www.cruk.manchester.ac.uk/Oppo[...]-Home

    Informal enquiries can be directed to Dr Claus Jorgensen via email: claus.jorgensen[at]cruk.manchester.ac.uk

    Job Ref: MI/18/25

    DEADLINE

    Closing date: 20 May 2018.

    BACKGROUND

    The Interdisciplinary Health Science Institute (IHSI) of the University of Illinois at Urbana-Champaign seeks applicants to fill a vacancy for Research Biostatistician to provide consultation and guidance to the clients of the Illinois Biostatistical Core (IBC).

    RESPONSIBILITIES

    • Provide expert statistical services and support, including statistical analysis, to Core clients using the appropriate computation and graphical software
    • Provide consultation to Core clients on study design, sample size calculations, and sample selection techniques
    • Provide consultation to Core clients on statistical sections of grant proposals, manuscripts, and other written work requiring biostatistical expertise
    • Have and maintain current knowledge of novel biostatistical methods
    • Have and maintain current knowledge of software that advances clinical/translational research
    • Prepare, conduct, and/or participate in training/classes/outreach for Core clients and other stakeholders
    • Perform other related tasks as needed to further the mission and goals of the IHSI

    REQUIREMENTS

    Required: Master's degree in applied statistics, biostatistics, or related field. At least 2 years of experience with analyzing data; related experience obtained while training will be considered/accepted. Strong background with standardized and specialized approaches for graphical and numerical data summary, data specifications, and data consistency checks. Proficiency using statistical software and packages (e.g., SAS, R, and SPSS). Experience conceptualizing research study designs and conducting analyses of complex data. Working knowledge or superior understanding of technical and applied principles including, but not limited to, generalized linear models, longitudinal data modeling techniques, missing data models, non-parametric modeling, and survival analysis. Sound judgment and excellent analytical and problem-solving skills. Effective communication, interpersonal, organizational, and team work skills. Demonstrated ability to perform effectively in a diverse and fast-paced work environment consisting of multiple and changing priorities, with minimal supervision, under stringent deadlines. Proficiency in commonly-employed software and databases.

    PREFERENCES

    PhD in applied statistics, biostatistics, or related field. Experience with consulting for health-related research in academic or industrial settings. Experience writing or reviewing statistical analysis plans, grant proposals. Experience with design and/or implementation of statistical training and/or education workshops. Experience with one or more of the following: imaging studies, statistical genetics, clinical trials, large data sets. Ability to contribute to the advancement of applied statistical techniques in biological research. Experience working within a Biostatistics Core and/or Medical College or Medical Center.

    TERMS

    Proposed start date: As soon as possible after closing date.

    LOCALE

    Illinois

    COMPENSATION

    Salary commensurate with education and experience.

    HOW TO APPLY

    To apply, all candidates must submit an online profile through jobs.illinois.edu by the close of the posting period. Qualified candidates must upload: 1) a letter which details qualifications noted above; 2) resume; and 3) the names and contact information for three professional references. All requested information must be submitted for your application to be considered completed. Incomplete applications will not be considered.

    For further information, please contact Kate Day, Human Resources, at OVCR-HR[at]illinois.edu.

    DEADLINE

    Applications must be received by May 15 , 2018.

    POLICY

    The University of Illinois conducts criminal background checks on all job candidates upon acceptance of a contingent offer.

    The University of Illinois is an Equal Opportunity, Affirmative Action employer. Minorities, women, veterans and individuals with disabilities are encouraged to apply. For more information, visit go.illinois.edu/EEO. To learn more about the University's commitment to diversity, please visit www.inclusiveillinois.illinois.edu

    BACKGROUND

    A new stealth-stage spinout of Specific Technologies (a Silicon Valley company) has partnered with the Sanger Institute's world leaders in pathogen genomics and is now looking for a senior bioinformatics software developer to help translate scientific research technology into a robust industrial level commercial product.

    The application to be developed will be put to highly demanding clinical use, and so will be built to industrial standards, and yet will constitute genuinely cutting-edge bioinformatics with the potential to have great impact on the field, as well as on patient lives.

    REQUIREMENTS

    Requirements include excellent software development skills, experience in development of large-scale bioinformatics data processing pipelines, quality control, automatization, TDD, knowledge of cloud platforms (e.g. AWS, Azure), sequence assembly, MGE identification, annotation and SNP-level dendrogram computation and interpretation. This role will eventually involve some managerial responsibilities as the team grows so being a team player and being confident with the prospect of becoming a team leader, with the ability and a desire to inspire and motivate others are additional qualities that we are looking for in a successful candidate.

    LOCALE

    You will be based in our newly opened office in the BioData Innovation Centre right on the legendary Wellcome Trust Genome Campus near Cambridge. Free Campus shuttles to and from Cambridge and number of other nearby locations are provided.

    COMPENSATION

    Salary package is fully competitive, with compensation to include significant stock options in the Silicon Valley tradition.

    HOW TO APPLY

    For further inquiries, please submit a letter explaining your interest, along with a CV, to: Eugene Bragin (ebragin[at]nextgen-dx.com)

    Submitter

    BACKGROUND

    Paramount are working in partnership with Genomics England to expand their team in order to deliver success with the 100,000 Genomes Project. This is a challenging and fast moving project with the aim to carry out whole genome sequencing on 100,000 participants. Genomics England works with key partners to collect, transport, store, quality check and sequence the samples from participants. The aim for this project is to create a new genomic medicine service for the NHS – transforming the way people are cared for. Patients may be offered a diagnosis where there wasn't one before. In time, there is the potential of new and more effective treatments.

    The post holder is an experienced Java / Front End developer responsible for creating server, web applications and REST APIs and utilising programming skills for the manipulation of data from large data sets. The post holder is responsible for developing and maintain applications within the Research Environment and supporting activities BAU activities including the data platform.

    RESPONSIBILITIES

    • Take an active role in story definition, building acceptance criteria for QA and liaison with product owners, project managers and other business stakeholders
    • Provide high quality , testable and performant software (greenfield development)
    • Work collaboratively with colleagues across the organisation using Agile development processes
    • Provide technical expertise on software development and be an active advocate for best development practices
    • Carry out development planning and estimating
    • Support pair programming and carrying out peer reviews
    • Develop services, databases and web applications for:
      • Analysing, modelling, searching and presenting clinical and genomic data
      • Integrate genomic API
    • Design and update software database. This includes, but is not limited to: Software Applications, Web Sites, Data Communication Processes and User Interfaces
    • Lead on trouble shooting to ensure effective deployment, maintenance and troubleshooting of software tools in the Research Environment

    REQUIREMENTS

    Skills/ Knowledge:
    • Must be a full-stack developer and understand concepts of software engineering
    • Degree in computer science or software engineering (or experience to this level)
    • Significant experience working on a variety of software development projects using different technologies including:
      • Proficiency in Java 8, Maven/Gradle, Spring, Persistence frameworks Hibernate/JPA, Junit, mocking frameworks
      • SQL and NoSQL databases
      • REST API development
      • Containerisation / Docker
      • Jenkins / CI
      • Front-end development (Javascript, HTML, CSS)
      • Experience utilising modern JS Frameworks such as React and Angular
      • Knowledge of OAuth / OpenID
    • Experience in designing and developing APIs and Microservices
    • Proficiency in collaborative development tools such as Github, Confluence and JIRA
    • Experience in data wrangling, management and ETL processes
    • Experienced in the development and execution of unit testing of code components or complete applications
    • Demonstrates strong problem solving and decision making skills while using sound judgment
    • Ability to work independently and to show initiative within a team
    • Ability to prioritise and balance competing demands
    • Works effectively within a multidisciplinary team
    • Communicates effectively and professionally in all forms of communication with internal and external customers
    • Flexible and co-operative approach to colleagues
    • Up-to-date knowledge of technological developments in the industry
    • Excellent attention to detail
    • 'Good to have's' include:
      • Experience of Cloud based applications delivery (e.g. AWS or similar)
      • Technical experience with Atlassian products e.g. Confluence plugins
      • Experience in the Health / Medical research sector advantageous
      • Experience in designing and developing software systems requiring scientific analysis, mathematical models and visualisation is advantageous.

    COMPENSATION

    There are some great benefits on offer with this role including a competitive salary, pension, generous holidays and more.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Senior, Software, Developer, Java, Front End, API, Spring, SQL, NoSQL, Restful, Junit, HTML, CSS, JavaScript, Jenkins, Docker, Bioinformatics, Genomics, AWS, London.

    Submitter

    BACKGROUND

    Pre-clinical – Statistics – RNAseq – DNAseq – Target Discovery – Quantitative Biology – Pharmaceutical

    Paramount have registered an exclusive position with a pharmaceutical company known worldwide. This organisation are keen to appoint an Associate Director or Director level expert in machine learning for their quantitative biology group. This position will work across a number of therapeutic areas, supporting projects in the drug discovery pipeline from target discovery all the way to clinical. You will lead a small team of data scientists with the purpose of providing quantitative insights to biology. You should be passionate about improving the biological understanding of targets and its engagement, and providing image and data analysis solutions to high dimensional datasets.

    This is a fantastic chance to continue your career in an organisation known for their innovative research and progression opportunities. You will be joining a talented and supportive team with expert skills in machine learning and data science.

    RESPONSIBILITIES

    Main Responsibilities:
    • Overseeing a team of data scientists and refining the departmental strategy for using machine learning to transform drug discovery
    • Using machine learning and statistical modelling you will collaborate with drug discovery projects, therapeutic areas and platform teams to identify and deliver solutions for addressing key questions across drug discovery
    • Developing appropriate algorithms, techniques and datasets to answer defined biological questions
    • Establishing academic collaborations to access and drive the forefronts machine learning science

    REQUIREMENTS

    Experience Required:
    • PhD, or equivalent, in mathematics, computer science, statistics, engineering or the life sciences
    • Experience in leading a small team and overseeing project delivery
    • Expertise in one or more of the core machine learning areas such as: ANNs, SVMs, Bayesian approaches, Markov models, Gaussian processes, reinforcement learning, game theory, decision theory, probabilistic rule-based learning.
    • Experience with relevant software tools such as R and Python as well as relevant machine learning frameworks
    • Basic understanding of molecular biology, cell biology, and human physiology
    • Excellent communication skills in English, spoken and in writing

    HOW TO APPLY

    For a confidential discussion about this role or to apply, please contact Jade at jpage[at]pararecruit.com

    Keywords: Machine Learning, Science, Preclinical, Quantitative Biology, RNAseq, DNAseq, Pharmaceutical, Sweden, United Kingdom, Europe

    DESCRIPTION

    The Quantitative RNA Biology group at Stockholm University and SciLifeLab is currently offering up to 2 PhD student positions. More information is available at:

    www.nature.com/natu[...]ology

    The Friedländer lab is specialised on miRNA function and biogenesis with a focus on single-cell biology. More information about the lab and its research can be found here:

    www.friedlanderlab.org

    The starting date is very much flexible.

    DEADLINE

    April 24, 2018

    Submitter

    BACKGROUND

    A very exciting position has just become available for a Senior Programmer, ideally with Bioinformatics skills to join a fast-growing start-up company in Hinxton, Cambridge. The successful candidate will be involved in the technical development of all aspects of the company's analysis platform: building and running pipelines, automation and scaling, and data management. This is an opportunity for an innovative individual to be involved at the early stages of this novel area of microbiome biomedicine and to help shape the informatics of the company to meet the needs of this new and evolving discipline. Innovation and problem-solving will be required and actively encouraged.

    RESPONSIBILITIES

    Key duties will include:
    • Design and develop the company analysis infrastructure
    • Implement production pipelines in a managed compute environment
    • Optimise and streamline production pipelines and processes
    • Evaluate and implement new tools and technologies as appropriate to improve and extend our technical capability
    • Extend pipelines to meet necessary industry standards
    • Collaborate in multi-disciplinary projects to ensure bioinformatics provision for therapeutic discovery and development

    REQUIREMENTS

    Candidate Specifications:
    Essential:
    • PhD or Masters in Informatics or Computer Science, or equivalent experience
    • Demonstrable experience of working in a production informatics environment
    • Experience with pipelining analyses on high-performance compute: farms, clusters, or cloud
    • Proficiency in a high-level programming language, eg; Python or Perl
    • Experience with software development best practices, including version control and testing
    • Fluency in Linux
    • Good communication and presentation skills
    • Flexibility to work in a new and dynamic company
    • Candidates must be legally entitled to work in the UK
    • An interest in biology
    Desirable:
    • DevOps / SysAdmin experience
    • Familiarity with Continuous Integration (eg; Jenkins/Travis)
    • Knowledge of Ansible or other automation tools such as Chef/Puppet
    • Experience with OpenStack or Amazon EC2
    • Experience analysing genomic/metagenomic sequence data

    COMPENSATION

    There are some great benefits available with this role as well as the opportunity to work with some of the best minds in genomics and software development.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Programming, Python, Perl, Software, Version Control, Linux, Jenkins, Git, Chef, Puppet, Bioinformatics, Genomics, Metagenomics, Microbiome, Cambridge

    BACKGROUND

    We are recruiting a technical assistant to join our work on dissecting the genetic and epigenetic basis of cancer and immune diseases using next generation sequencing. Our lab is based at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna, on the campus of one of the world's largest hospitals and medical schools, pursuing an ambitious research program in molecular medicine.

    At CeMM, we take career development of our staff seriously. For example, we will train the successful candidate in state-of-the-art technologies that are in high demand in academia and industry, and we encourage contribution to and co-authorship of scientific publications. Importantly, genomic medicine is a hot topic in Austria and internationally, creating a highly promising area for a career in biomedical research and applications.

    RESPONSIBILITIES

    Typical Tasks:
    • Library preparation for next generation sequencing (manually and with automated systems)
    • Next generation sequencing on Illumina machines (NovaSeq, HiSeq 3000/4000, NextSeq, Miseq, etc.)
    • Optimization and testing of new protocols, e.g. for CRISPR screens, single-cell sequencing, and epigenome editing
    • Troubleshooting of technical problems in the sample preparation and sequencing workflows
    • Contribution to lab management, training of new lab members, and scientific publications

    REQUIREMENTS

    • Bachelor or Master degree (or equivalent) with strong wet-lab experience
    • High accuracy, reliability, precision under time pressure, and organizational skills
    • High motivation and commitment, proactive mindset, getting-things-done attitude
    • Prior experience working with DNA and/or RNA assays is mandatory. Experience with next generation sequencing is a plus
    • Friendly, collaborative mindset and ability to work well in an international environment
    • Written and oral communication skills in English (German skills are not required)
    • Motivation to work in one of the fastest-moving and most future-oriented areas of biomedicine

    HOW TO APPLY

    Please apply online (cemm.jobbase.io/job/rpqarnnb) with cover letter, CV, academic transcripts, and contact details of three referees. Applications will be reviewed on a rolling basis. Any application received by 31 May 2018 will be considered. Start dates are flexible.

    DEADLINE

    31 May 2018

    Submitter

    BACKGROUND

    This is a great opportunity for an experienced bioinformatician with expertise in analysing microbial genomes, ideally in a metagenomics context. The ideal candidate will be an enthusiastic individual looking to play a key role in building a new biotech company and to contribute to the development of a new class of medicines.

    RESPONSIBILITIES

    The successful candidate will be responsible for the development of methods and workflows to enable the annotation and interpretation of genomes and metagenomes associated with healthy and diseased states. Studies will be undertaken with large clinical datasets using metagenomics and AI to define microbiome bacterial signatures associated with disease and drug response and constituting potential therapies or diagnostics. This is an opportunity to be involved at the early stages of this novel area of microbiome biomedicine and to help shape the informatics and analytics of the company to meet the needs of this new discipline. Innovation and problem-solving will be required and actively encouraged.

    Key duties will include:
    • Develop and run methods, metrics, and pipelines for the automatic functional annotation of genomic and microbiome data
    • Develop tools and databases capable of integrating and comparing large-scale (meta)genomics datasets and their associated metadata
    • Collaborate in multi-disciplinary projects to perform end-to-end data analysis toward therapeutic discovery and development
    • Identify, develop and implement new analytical, statistical and machine-learning methods to improve and extend our informatics platform

    REQUIREMENTS

    Candidate Specifications:
    Essential:
    • PhD or Masters in Bioinformatics or related discipline, or equivalent experience
    • 5 years of experience in bioinformatics and/or sequence data analysis
    • Demonstrable experience of microbial genomics and/or metagenomics
    • Proficiency in a high-level programming language, eg; Python or Perl
    • Familiarity with Linux command-line environment
    • Good communication and presentation skills
    • Flexibility to work in a new and dynamic company
    • Role holder will be an independent self-starter, looking to learn and acquire new skills
    • Candidates must be legally entitled to work in the UK
    Desirable:
    • Familiarity with phylogenetic/taxonomic classification of genomes and metagenomes
    • Experience with gene, protein and pathway annotation tools and databases
    • Knowledge of machine learning
    • Background in statistics
    • Familiarity with other `omics' data: transcriptomics, metabolomics, etc
    • Experience with running analyses on high-performance compute: farms, clusters, or cloud

    COMPENSATION

    There are some great benefits available with this role as well as the opportunity to work with some of the best minds in genomics and software development.

    HOW TO APPLY

    Please do not hesitate to contact Harvey Uppal at huppal[at]pararecruit.com or call (+44) 121 616 3407 to discuss this opportunity further.

    Keywords: Programming, Python, Perl, Software, Version Control, Linux, Jenkins, Git, Chef, Puppet, Bioinformatics, Genomics, Metagenomics, Microbiome, Machine Learning, Statistics, Cambridge.

    BACKGROUND

    A new stealth-stage spinout of Specific Technologies (a Silicon Valley company) has partnered with the Sanger Institute's world leaders in pathogen genomics and is now looking for a bioinformatician to help translate scientific research technology into a robust industrial level commercial product.

    The application to be developed will be put to highly demanding clinical use, and so will be built to industrial standards, and yet will constitute genuinely cutting-edge bioinformatics with the potential to have great impact on the field, as well as on patient lives.

    REQUIREMENTS

    Requirements include understanding of most modern sequencing technologies such as Illumina, PacBio and Oxford Nanopore, experience in processing their data and dealing with artIfacts that come with it. Ideal candidate would have deep knowledge of pathogens genome, sequence assembly, MGE identification, annotation and SNP-level dendrogram computation and interpretation, antimicrobial resistance mechanisms and genetic determinants that cause them.

    TERMS

    Job Type: Full-time

    LOCALE

    You will be based in our newly opened office in the BioData Innovation Centre right on the legendary Wellcome Trust Genome Campus near Cambridge, UK. Free Campus shuttles to and from Cambridge and number of other nearby locations are provided.

    COMPENSATION

    Salary package is fully competitive, with compensation to include stock options in the Silicon Valley tradition.

    Salary: £35,000.00 to £55,000.00/year

    HOW TO APPLY

    For further inquiries, please submit a letter explaining your interest, along with a CV, to: Eugene Bragin (ebragin[at]nextgen-dx.com)

    RESPONSIBILITIES

    The Department of Plant-Microbe Interactions at Max Plank Institute for Plant Breeding Research (MPIPZ) in Cologne, Germany, invites applications for a

    Postdoctoral position in Bioinformatics

    The successful applicant will be expected to develop and apply computational tools for the analysis of high-throughput sequencing amplicon, (meta)genome and (meta)transcriptome data. Candidates are expected to interact closely with computer scientists and experimental biologists and employ computational approaches to deepen our understanding of the evolution and functions of the plant microbiota as well as its interface with the plant innate immune system.

    REQUIREMENTS

    We seek a creative and motivated candidate with a PhD in computer science, bioinformatics, statistics or related field. The applicant should be proficient in the use of Linux/Unix and have proven experience in scripting and software development (e.g. Python, C/C++, Java, R). Experience in analysis of next generation sequencing data is desired. The ability to work in an environment at the interface of biology and computer sciences in addition to good communication skills are essential.

    TERMS

    The position will be offered for 2 years with the possibility of extension and are available immediately.

    COMPENSATION

    Salary and benefits are commensurate with public service regulation (TvöD).

    HOW TO APPLY

    For questions concerning the position, please contact Dr. Ruben Garrido-Oter (garridoo[at]mpipz.mpg.de). Applications consisting of a cover letter, curriculum vitae, list of publications and the name of at least one academic referee should be combined as a single PDF and uploaded to our online application platform:

    s-lotus.gwdg.de/mpg/[...]ungen

    DEADLINE

    By May 15th 2018. Interviews with shortlisted candidates will be held on May 30th 2018.

    POLICY

    The Max-Planck Society is committed to increasing the number of individuals with disabilities in its workforce and therefore encourages applications from such qualified individuals. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encourages women to apply.

    Submitter

    BACKGROUND

    Paramount are now working with a thriving consumer genetics company based near Bristol who have released an opportunity for a talented Data Scientist to join them at their brand new offices based near Bristol.

    As a Data Scientist with this innovative business, you will be working with complex, high-dimensional data sets, applying expert analysis and machine learning techniques. The company delivers a fast, personalised service that provides fascinating insights into a person's ancestry, heritage and even a tailored nutrition guide based entirely on what is required by a person's individual genetic make-up!

    RESPONSIBILITIES

    Key responsibilities of the Data Scientist will be:
    • Working in a HPC environment, performing analysis of complex data and implementing advanced algorithms to extract key insights
    • Working closely across multi-disciplinary teams from Product, Research and Technology to help formulate the machine learning product vision and design
    • Inform research strategy and business-critical decisions
    • Communicate effectively in multi-cultural, dynamic teams

    REQUIREMENTS

    Essential skills required by the Data Scientist:
    • Advanced knowledge of Python, including SciPy, Numpy, Pandas etc.
    • Familiarity with a range of visualisation tools such as seaborn, ggplot and matplotlib
    • Demonstrable knowledge of data mining algorithms including machine learning techniques such as decision trees, deep learning, neural networks, probability networks, clustering and regression
    • An MSc or PhD in Computer Science, Machine Learning, Data Science, Bioinformatics or a related discipline
    • Prior experience working with biomedical data eg, genomics, proteomics, epigenomics

    COMPENSATION

    On offer is a competitive package, flexible working, brand new offices, a fantastic team environment and the opportunity to work with cutting edge technology.

    HOW TO APPLY

    For more information, send your CV to efrancis[at]pararecruit.com. For an informal chat about the position, call Emilie on 0121 616 3477.

    Key words: Machine Learning, Data Science, Genomics, Ancestry, Artificial Intelligence, Data Scientist, Bristol, Computer Science, Computational Biology, DNA Testing

    Submitter

    BACKGROUND

    Brand new opportunity for a Head of Bioinformatics at one of the country's most exciting biotechs, heading up pioneering research into the next generation of personalised medicines for cancer. This is an opportunity for a talented and experienced Bioinformatician with a strong strategic mind and excellent leadership ability.

    RESPONSIBILITIES

    Key responsibilities for Head of Bioinformatics include:
    • Lead bioinformatics strategy
    • Build, develop and mentor a multi-disciplinary, high performance team
    • Partner with Senior Heads across a variety of departments (Clinical, Manufacturing, Regulatory)

    REQUIREMENTS

    The ideal candidate for Head of Bioinformatics will have:
    • A PhD in Bioinformatics, Computational Biology or a related field
    • Significant experience of leading teams/working in a strategic capacity
    • A background specialised in oncology is highly desirable
    • Experience of translational bioinformatics and drug discovery
    • Experience of working in a regulated environment
    • A high-energy, hands-on approach
    • A passion for working in a fast-paced, biotech environment

    HOW TO APPLY

    This is a unique opportunity to be a driving force in an organisation that could revolutionise the industry and change the way cancer patients are treated. For more information on this or similar roles, please send your CV to efrancis[at]pararecruit.com, or call Emilie on 0121 616 3477.

    Key words: Cancer, Oncology, Biotech, Start-up, Bioinformatics, Director, Head, Genomics, Hertfordshire, Cambridge, Oxford

    Submitter

    BACKGROUND

    Paramount are working closely with a successful young Biotech based in the heart of Cambridge who are looking for enthusiastic Data Scientists with expertise in metabolic modelling.

    Using expert machine learning and advanced analytics, this progressive start-up is dedicated to identifying new therapeutics for the millions of children that are suffering with rare diseases, for whom there are currently extremely limited treatment options available.

    This Data Scientist position will join an already established and talented team of Computer Scientists, and contribute to the development of in silico drug discovery solutions, using pioneering metabolic modelling approaches.

    This is vital role that will contribute to critical scientific research that could the vastly improve the quality of life for millions of people. This role has the chance to interact personally with the patient groups who will be directly benefiting from this cutting edge technology, making this opportunity hugely rewarding for those who are passionate about the work.

    REQUIREMENTS

    The ideal candidate will have:
    • A PhD in Computer Science, Mathematics or a related discipline
    • Expertise in the field of metabolic modelling, with experience of COBRA toolbox and Flux Balance Analysis based techniques and results interpretation
    • Proven experience of developing and implementing novel algorithms from scratch
    • Experience of Linear programming/algebra
    • Advanced user of mathematical/statistical programming languages, eg. Matlab, Python, R
    • Graph theory and network analysis
    • Biochemical pathway analysis

    COMPENSATION

    On offer is a competitive salary, flexible working, fantastic location and a wonderfully talented team of people.

    HOW TO APPLY

    To apply, send your CV to efrancis[at]pararecruit.com, or for more information, call Emilie on 0121 616 3477.

    Key words: Rare Disease, Orphan Disease, Metabolomics, Metabolic Modelling, Mathematical Modelling, Data Science, Machine Learning, Artificial Intelligence, Cambridge, Personalised Medicine, Drug Discovery, Data Scientist

    Submitter

    BACKGROUND

    Paramount are working closely with a successful young Biotech based in the heart of Cambridge who are looking for enthusiastic junior Data Scientists/PostDocs with expertise in metabolic modelling.

    Using expert machine learning and advanced analytics, this progressive start-up is dedicated to identifying new therapeutics for the millions of children that are suffering with rare diseases, for whom there are currently extremely limited treatment options available.

    This PostDoc / Junior Data Scientist position will join an already established and talented team of Computer Scientists, and contribute to the development of in silico drug discovery solutions, using pioneering metabolic modelling approaches.

    This is vital role that will contribute to critical scientific research that could the vastly improve the quality of life for millions of people. This role has the chance to interact personally with the patient groups who will be directly benefiting from this cutting edge technology, making this opportunity hugely rewarding for those who are passionate about the work.

    REQUIREMENTS

    The ideal candidate will have:
    • A PhD in Computer Science, Mathematics or a related discipline
    • Expertise in the field of metabolic modelling, with experience of COBRA toolbox and Flux Balance Analysis based techniques and results interpretation
    • Proven experience of developing and implementing novel algorithms from scratch
    • Experience of Linear programming/algebra
    • Advanced user of mathematical/statistical programming languages, eg. Matlab, Python, R
    • Graph theory and network analysis
    • Biochemical pathway analysis

    COMPENSATION

    On offer is a competitive salary, flexible working, fantastic location and a wonderfully talented team of people.

    HOW TO APPLY

    To apply, send your CV to efrancis[at]pararecruit.com, or for more information, call Emilie on 0121 616 3477.

    Key words: Rare Disease, Orphan Disease, Metabolomics, Metabolic Modelling, Mathematical Modelling, Data Science, Machine Learning, Artificial Intelligence, Cambridge, Personalised Medicine, Drug Discovery, Data Scientist
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