Basic Information
Gene ID 100972175
Gene Name MYC
Full Name Myc proto-oncogene protein
Organism Pan paniscus [9597]

Cross Reference
UniProt A1YG22 UniGene NULL
PDB NULL OMIM NULL
KEGG pps:100972175 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003820503 Gene3D G3DSA:4.10.280.10 IPR011598 355 428 6.00e-18 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003820503 Pfam PF00010 IPR011598 355 407 3.90e-15 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003820503 Pfam PF01056 IPR012682 1 345 2.10e-140 Transcription regulator Myc, N-terminal
XP_003820503 Pfam PF02344 IPR003327 408 439 7.90e-19 Leucine zipper, Myc
XP_003820503 PIRSF PIRSF001705 IPR002418 1 437 0.00e-00 Transcription regulator Myc
XP_003820503 PRINTS PR00044 IPR002418 128 143 5.30e-51 Transcription regulator Myc
XP_003820503 PRINTS PR00044 IPR002418 304 313 5.30e-51 Transcription regulator Myc
XP_003820503 PRINTS PR00044 IPR002418 347 363 5.30e-51 Transcription regulator Myc
XP_003820503 PRINTS PR00044 IPR002418 364 379 5.30e-51 Transcription regulator Myc
XP_003820503 PRINTS PR00044 IPR002418 389 402 5.30e-51 Transcription regulator Myc
XP_003820503 PRINTS PR00044 IPR002418 45 63 5.30e-51 Transcription regulator Myc
XP_003820503 ProSiteProfiles PS50888 IPR011598 354 406 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003820503 SMART SM00353 IPR011598 360 412 3.60e-17 Myc-type, basic helix-loop-helix (bHLH) domain
XP_003820503 SUPERFAMILY SSF47459 IPR011598 352 435 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003820503 PF01056 0 Myc_N Myc amino-terminal region
XP_003820503 PF02344 7.9e-19 Myc-LZ Myc leucine zipper domain
XP_003820503 PF00010 2e-16 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003820503 GO:0000165 biological_process MAPK cascade
XP_003820503 GO:0006338 biological_process chromatin remodeling
XP_003820503 GO:0006351 biological_process transcription, DNA-templated
XP_003820503 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003820503 GO:0006879 biological_process cellular iron ion homeostasis
XP_003820503 GO:0006974 biological_process cellular response to DNA damage stimulus
XP_003820503 GO:0010332 biological_process response to gamma radiation
XP_003820503 GO:0032204 biological_process regulation of telomere maintenance
XP_003820503 GO:0032873 biological_process negative regulation of stress-activated MAPK cascade
XP_003820503 GO:0042493 biological_process response to drug
XP_003820503 GO:0043066 biological_process negative regulation of apoptotic process
XP_003820503 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
XP_003820503 GO:0045656 biological_process negative regulation of monocyte differentiation
XP_003820503 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_003820503 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
XP_003820503 GO:0048146 biological_process positive regulation of fibroblast proliferation
XP_003820503 GO:0050679 biological_process positive regulation of epithelial cell proliferation
XP_003820503 GO:0051276 biological_process chromosome organization
XP_003820503 GO:0051782 biological_process negative regulation of cell division
XP_003820503 GO:0060070 biological_process canonical Wnt signaling pathway
XP_003820503 GO:2000573 biological_process positive regulation of DNA biosynthetic process
XP_003820503 GO:2001022 biological_process positive regulation of response to DNA damage stimulus
XP_003820503 GO:0005634 cellular_component nucleus
XP_003820503 GO:0005654 cellular_component nucleoplasm
XP_003820503 GO:0005730 cellular_component nucleolus
XP_003820503 GO:0003677 molecular_function DNA binding
XP_003820503 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
XP_003820503 GO:0032403 molecular_function protein complex binding
XP_003820503 GO:0046983 molecular_function protein dimerization activity
XP_003820503 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100758352 10224 Saccoglossus kowalevskii 100303478
39432 Saimiri boliviensis 101047066 9606 Homo sapiens 4609
9544 Macaca mulatta 694626 9646 Ailuropoda melanoleuca ENSAMEG00000014717
9615 Canis familiaris ENSCAFG00000001086 59463 Myotis lucifugus ENSMLUG00000026933
13616 Monodelphis domestica ENSMODG00000001735 9258 Ornithorhynchus anatinus ENSOANG00000008107
8128 Oreochromis niloticus ENSONIG00000013987 9601 Pongo abelii ENSPPYG00000018878
13735 Pelodiscus sinensis ENSPSIG00000008301 10116 Rattus norvegicus ENSRNOG00000004500
9823 Sus scrofa ENSSSCG00000005965 31033 Takifugu rubripes ENSTRUG00000008797
9739 Tursiops truncatus ENSTTRG00000016278 30538 Vicugna pacos ENSVPAG00000005895
9555 Papio anubis 101000645 43179 Ictidomys tridecemlineatus 101957086
8083 Xiphophorus maculatus 102224917 7897 Latimeria chalumnae 102357079
7955 Danio rerio 393141 9031 Gallus gallus 420332
28377 Anolis carolinensis ENSACAG00000010372 9483 Callithrix jacchus ENSCJAG00000012620
10141 Cavia porcellus ENSCPOG00000003326 10020 Dipodomys ordii ENSDORG00000010277
9365 Erinaceus europaeus ENSEEUG00000001458 9685 Felis catus ENSFCAG00000025438
69293 Gasterosteus aculeatus ENSGACG00000004456 9595 Gorilla gorilla ENSGGOG00000012135
8049 Gadus morhua ENSGMOG00000006081 9785 Loxodonta africana ENSLAFG00000001410
9315 Macropus eugenii ENSMEUG00000006124 9103 Meleagris gallopavo ENSMGAG00000015875
30608 Microcebus murinus ENSMICG00000014990 9669 Mustela putorius furo ENSMPUG00000001327
9986 Oryctolagus cuniculus ENSOCUG00000014289 30611 Otolemur garnettii ENSOGAG00000005372
9978 Ochotona princeps ENSOPRG00000011259 8090 Oryzias latipes ENSORLG00000007021
9813 Procavia capensis ENSPCAG00000008554 9598 Pan troglodytes ENSPTRG00000020581
42254 Sorex araneus ENSSARG00000010372 37347 Tupaia belangeri ENSTBEG00000005715
59729 Taeniopygia guttata ENSTGUG00000012513 99883 Tetraodon nigroviridis ENSTNIG00000017136