Basic Information
Gene ID ENSMEUG00000006124
Gene Name ENSMEUG00000006124
Full Name ENSMEUG00000006124
Organism Macropus eugenii [9315]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMEUP00000005588 Gene3D G3DSA:4.10.280.10 IPR011598 369 447 1.70e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000005588 Pfam PF00010 IPR011598 369 421 3.00e-14 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000005588 Pfam PF01056 IPR012682 15 51 1.50e-12 Transcription regulator Myc, N-terminal
ENSMEUP00000005588 Pfam PF01056 IPR012682 267 359 5.70e-39 Transcription regulator Myc, N-terminal
ENSMEUP00000005588 Pfam PF02344 IPR003327 422 453 2.20e-06 Leucine zipper, Myc
ENSMEUP00000005588 PIRSF PIRSF001705 IPR002418 11 451 8.30e-42 Transcription regulator Myc
ENSMEUP00000005588 PRINTS PR00044 IPR002418 318 327 1.00e-28 Transcription regulator Myc
ENSMEUP00000005588 PRINTS PR00044 IPR002418 361 377 1.00e-28 Transcription regulator Myc
ENSMEUP00000005588 PRINTS PR00044 IPR002418 378 393 1.00e-28 Transcription regulator Myc
ENSMEUP00000005588 PRINTS PR00044 IPR002418 403 416 1.00e-28 Transcription regulator Myc
ENSMEUP00000005588 ProSiteProfiles PS50888 IPR011598 368 420 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000005588 SMART SM00353 IPR011598 374 426 1.80e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000005588 SUPERFAMILY SSF47459 IPR011598 366 448 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMEUP00000005588 PF01056 0 Myc_N Myc amino-terminal region
ENSMEUP00000005588 PF00010 1.7e-14 HLH Helix-loop-helix DNA-binding domain
ENSMEUP00000005588 PF02344 2.2e-06 Myc-LZ Myc leucine zipper domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMEUP00000005588 GO:0000165 biological_process MAPK cascade
ENSMEUP00000005588 GO:0006338 biological_process chromatin remodeling
ENSMEUP00000005588 GO:0006351 biological_process transcription, DNA-templated
ENSMEUP00000005588 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMEUP00000005588 GO:0006879 biological_process cellular iron ion homeostasis
ENSMEUP00000005588 GO:0006974 biological_process cellular response to DNA damage stimulus
ENSMEUP00000005588 GO:0010332 biological_process response to gamma radiation
ENSMEUP00000005588 GO:0032204 biological_process regulation of telomere maintenance
ENSMEUP00000005588 GO:0032873 biological_process negative regulation of stress-activated MAPK cascade
ENSMEUP00000005588 GO:0042493 biological_process response to drug
ENSMEUP00000005588 GO:0043066 biological_process negative regulation of apoptotic process
ENSMEUP00000005588 GO:0043280 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
ENSMEUP00000005588 GO:0045656 biological_process negative regulation of monocyte differentiation
ENSMEUP00000005588 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMEUP00000005588 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMEUP00000005588 GO:0048146 biological_process positive regulation of fibroblast proliferation
ENSMEUP00000005588 GO:0050679 biological_process positive regulation of epithelial cell proliferation
ENSMEUP00000005588 GO:0051276 biological_process chromosome organization
ENSMEUP00000005588 GO:0051782 biological_process negative regulation of cell division
ENSMEUP00000005588 GO:0060070 biological_process canonical Wnt signaling pathway
ENSMEUP00000005588 GO:2000573 biological_process positive regulation of DNA biosynthetic process
ENSMEUP00000005588 GO:2001022 biological_process positive regulation of response to DNA damage stimulus
ENSMEUP00000005588 GO:0005634 cellular_component nucleus
ENSMEUP00000005588 GO:0005654 cellular_component nucleoplasm
ENSMEUP00000005588 GO:0005730 cellular_component nucleolus
ENSMEUP00000005588 GO:0003677 molecular_function DNA binding
ENSMEUP00000005588 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMEUP00000005588 GO:0032403 molecular_function protein complex binding
ENSMEUP00000005588 GO:0046983 molecular_function protein dimerization activity
ENSMEUP00000005588 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100758352 9555 Papio anubis 101000645
43179 Ictidomys tridecemlineatus 101957086 8083 Xiphophorus maculatus 102224917
7897 Latimeria chalumnae 102357079 7955 Danio rerio 393141
9031 Gallus gallus 420332 28377 Anolis carolinensis ENSACAG00000010372
9483 Callithrix jacchus ENSCJAG00000012620 10141 Cavia porcellus ENSCPOG00000003326
10020 Dipodomys ordii ENSDORG00000010277 9365 Erinaceus europaeus ENSEEUG00000001458
9685 Felis catus ENSFCAG00000025438 69293 Gasterosteus aculeatus ENSGACG00000004456
9595 Gorilla gorilla ENSGGOG00000012135 8049 Gadus morhua ENSGMOG00000006081
9785 Loxodonta africana ENSLAFG00000001410 9597 Pan paniscus 100972175
39432 Saimiri boliviensis 101047066 9606 Homo sapiens 4609
9544 Macaca mulatta 694626 9646 Ailuropoda melanoleuca ENSAMEG00000014717
9615 Canis familiaris ENSCAFG00000001086 59463 Myotis lucifugus ENSMLUG00000026933
13616 Monodelphis domestica ENSMODG00000001735 9258 Ornithorhynchus anatinus ENSOANG00000008107
8128 Oreochromis niloticus ENSONIG00000013987 9601 Pongo abelii ENSPPYG00000018878
13735 Pelodiscus sinensis ENSPSIG00000008301 10116 Rattus norvegicus ENSRNOG00000004500
9823 Sus scrofa ENSSSCG00000005965 31033 Takifugu rubripes ENSTRUG00000008797
9739 Tursiops truncatus ENSTTRG00000016278 30538 Vicugna pacos ENSVPAG00000005895
9103 Meleagris gallopavo ENSMGAG00000015875 30608 Microcebus murinus ENSMICG00000014990
9669 Mustela putorius furo ENSMPUG00000001327 9986 Oryctolagus cuniculus ENSOCUG00000014289
30611 Otolemur garnettii ENSOGAG00000005372 9978 Ochotona princeps ENSOPRG00000011259
8090 Oryzias latipes ENSORLG00000007021 9598 Pan troglodytes ENSPTRG00000020581
42254 Sorex araneus ENSSARG00000010372 37347 Tupaia belangeri ENSTBEG00000005715
59729 Taeniopygia guttata ENSTGUG00000012513 99883 Tetraodon nigroviridis ENSTNIG00000017136