Basic Information
Gene ID 100988818
Gene Name PAX8
Full Name PREDICTED: paired box protein Pax-8 isoform 1 [Pan paniscus].
Organism Pan paniscus [9597]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
XP_003804538 Gene3D G3DSA:1.10.10.10 IPR011991 12 77 6.10e-40 Winged helix-turn-helix DNA-binding domain
XP_003804538 Gene3D G3DSA:1.10.10.10 IPR011991 78 138 2.60e-36 Winged helix-turn-helix DNA-binding domain
XP_003804538 Pfam PF00292 IPR001523 9 133 4.20e-71 Paired domain
XP_003804538 Pfam PF12403 IPR022130 343 455 1.50e-50 Paired-box protein 2 C-terminal
XP_003804538 PRINTS PR00027 IPR001523 13 28 3.90e-43 Paired domain
XP_003804538 PRINTS PR00027 IPR001523 31 49 3.90e-43 Paired domain
XP_003804538 PRINTS PR00027 IPR001523 51 68 3.90e-43 Paired domain
XP_003804538 PRINTS PR00027 IPR001523 69 86 3.90e-43 Paired domain
XP_003804538 ProSitePatterns PS00034 IPR001523 43 59 - Paired domain
XP_003804538 ProSiteProfiles PS51057 IPR001523 9 135 0.00e-00 Paired domain
XP_003804538 SMART SM00351 IPR001523 9 133 1.00e-95 Paired domain
XP_003804538 SUPERFAMILY SSF46689 IPR009057 11 133 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
XP_003804538 PF00292 0 PAX 'Paired box' domain
XP_003804538 PF12403 0 Pax2_C Paired-box protein 2 C terminal
XP_003804538 PF13384 0.00013 HTH_23 Homeodomain-like domain

Gene Ontology Annotation
Protein Entry Name Space Description
XP_003804538 GO:0006351 biological_process transcription, DNA-templated
XP_003804538 GO:0006355 biological_process regulation of transcription, DNA-templated
XP_003804538 GO:0007275 biological_process multicellular organismal development
XP_003804538 GO:0045893 biological_process positive regulation of transcription, DNA-templated
XP_003804538 GO:0048793 biological_process pronephros development
XP_003804538 GO:2000611 biological_process positive regulation of thyroid hormone generation
XP_003804538 GO:0005634 cellular_component nucleus
XP_003804538 GO:0003677 molecular_function DNA binding
XP_003804538 GO:0044212 molecular_function transcription regulatory region DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100701954 9544 Macaca mulatta 701906
9913 Bos taurus ENSBTAG00000019354 10141 Cavia porcellus ENSCPOG00000012011
69293 Gasterosteus aculeatus ENSGACG00000016747 9669 Mustela putorius furo ENSMPUG00000009512
8090 Oryzias latipes ENSORLG00000007225 9813 Procavia capensis ENSPCAG00000005498
9305 Sarcophilus harrisii ENSSHAG00000011845 9823 Sus scrofa ENSSSCG00000021332
43179 Ictidomys tridecemlineatus ENSSTOG00000024664 31033 Takifugu rubripes ENSTRUG00000018667
9739 Tursiops truncatus ENSTTRG00000011948 30538 Vicugna pacos ENSVPAG00000003973
8083 Xiphophorus maculatus ENSXMAG00000005467 9555 Papio anubis 101026378
39432 Saimiri boliviensis 101036832 9595 Gorilla gorilla 101137174
9615 Canis familiaris 403927 9606 Homo sapiens 7849
9646 Ailuropoda melanoleuca ENSAMEG00000010662 9483 Callithrix jacchus ENSCJAG00000013889
7955 Danio rerio ENSDARG00000015879 10020 Dipodomys ordii ENSDORG00000002606
9796 Equus caballus ENSECAG00000009244 9685 Felis catus ENSFCAG00000009580
8049 Gadus morhua ENSGMOG00000011083 7897 Latimeria chalumnae ENSLACG00000003762
9785 Loxodonta africana ENSLAFG00000021590 9315 Macropus eugenii ENSMEUG00000013983
30608 Microcebus murinus ENSMICG00000003265 59463 Myotis lucifugus ENSMLUG00000011936
13616 Monodelphis domestica ENSMODG00000013770 61853 Nomascus leucogenys ENSNLEG00000002157
9258 Ornithorhynchus anatinus ENSOANG00000010554 9986 Oryctolagus cuniculus ENSOCUG00000004187
30611 Otolemur garnettii ENSOGAG00000009418 9598 Pan troglodytes ENSPTRG00000012380
132908 Pteropus vampyrus ENSPVAG00000005666 10116 Rattus norvegicus ENSRNOG00000026203
42254 Sorex araneus ENSSARG00000014324 37347 Tupaia belangeri ENSTBEG00000008679
99883 Tetraodon nigroviridis ENSTNIG00000009029 9478 Tarsius syrichta ENSTSYG00000012543
8364 Xenopus tropicalis ENSXETG00000001272

Paralogs
100982936