Basic Information
Gene ID ENSPTRG00000012380
Gene Name PAX8
Full Name Uncharacterized protein
Organism Pan troglodytes [9598]

Cross Reference
UniProt H2R8M9 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPTRP00000051762 Gene3D G3DSA:1.10.10.10 IPR011991 12 77 4.50e-40 Winged helix-turn-helix DNA-binding domain
ENSPTRP00000051762 Gene3D G3DSA:1.10.10.10 IPR011991 78 129 1.60e-31 Winged helix-turn-helix DNA-binding domain
ENSPTRP00000051762 Pfam PF00292 IPR001523 9 129 6.60e-69 Paired domain
ENSPTRP00000051762 Pfam PF12403 IPR022130 265 375 1.10e-50 Paired-box protein 2 C-terminal
ENSPTRP00000051762 PRINTS PR00027 IPR001523 13 28 2.00e-43 Paired domain
ENSPTRP00000051762 PRINTS PR00027 IPR001523 31 49 2.00e-43 Paired domain
ENSPTRP00000051762 PRINTS PR00027 IPR001523 51 68 2.00e-43 Paired domain
ENSPTRP00000051762 PRINTS PR00027 IPR001523 69 86 2.00e-43 Paired domain
ENSPTRP00000051762 ProSitePatterns PS00034 IPR001523 43 59 - Paired domain
ENSPTRP00000051762 ProSiteProfiles PS51057 IPR001523 9 135 0.00e-00 Paired domain
ENSPTRP00000051762 SMART SM00351 IPR001523 9 133 1.20e-90 Paired domain
ENSPTRP00000051762 SUPERFAMILY SSF46689 IPR009057 11 129 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPTRP00000051762 PF00292 0 PAX 'Paired box' domain
ENSPTRP00000051762 PF12403 0 Pax2_C Paired-box protein 2 C terminal
ENSPTRP00000051762 PF13384 0.00011 HTH_23 Homeodomain-like domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPTRP00000051762 GO:0006351 biological_process transcription, DNA-templated
ENSPTRP00000051762 GO:0007275 biological_process multicellular organismal development
ENSPTRP00000051762 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPTRP00000051762 GO:2000611 biological_process positive regulation of thyroid hormone generation
ENSPTRP00000051762 GO:0005634 cellular_component nucleus
ENSPTRP00000051762 GO:0003677 molecular_function DNA binding
ENSPTRP00000051762 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSPTRP00000051762 GO:0044212 molecular_function transcription regulatory region DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9555 Papio anubis 101026378 39432 Saimiri boliviensis 101036832
9595 Gorilla gorilla 101137174 9615 Canis familiaris 403927
9606 Homo sapiens 7849 9646 Ailuropoda melanoleuca ENSAMEG00000010662
9796 Equus caballus ENSECAG00000009244 9685 Felis catus ENSFCAG00000009580
9785 Loxodonta africana ENSLAFG00000021590 30608 Microcebus murinus ENSMICG00000003265
59463 Myotis lucifugus ENSMLUG00000011936 13616 Monodelphis domestica ENSMODG00000013770
61853 Nomascus leucogenys ENSNLEG00000002157 9986 Oryctolagus cuniculus ENSOCUG00000004187
30611 Otolemur garnettii ENSOGAG00000009418 9978 Ochotona princeps ENSOPRG00000012910
9597 Pan paniscus 100988818 9544 Macaca mulatta 701906
9913 Bos taurus ENSBTAG00000019354 10141 Cavia porcellus ENSCPOG00000012011
10020 Dipodomys ordii ENSDORG00000002606 9669 Mustela putorius furo ENSMPUG00000009512
42254 Sorex araneus ENSSARG00000014324 9305 Sarcophilus harrisii ENSSHAG00000011845
43179 Ictidomys tridecemlineatus ENSSTOG00000024664 132908 Pteropus vampyrus ENSPVAG00000005666
10116 Rattus norvegicus ENSRNOG00000026203 9478 Tarsius syrichta ENSTSYG00000012543

Paralogs
744540