Basic Information
Gene ID 12355 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nr1i3; Car
Full Name Nuclear receptor subfamily 1 group I member 3
Organism Mus musculus [10090]

Cross Reference
UniProt O35627 UniGene Mm.486506
PDB 1XNX OMIM NULL
KEGG mmu:12355 UCSC uc007dng.2

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000005820 Gene3D G3DSA:1.10.565.10 IPR008946 138 357 2.10e-59 Nuclear hormone receptor, ligand-binding
ENSMUSP00000005820 Gene3D G3DSA:1.10.565.10 IPR008946 75 105 2.10e-59 Nuclear hormone receptor, ligand-binding
ENSMUSP00000005820 Gene3D G3DSA:3.30.50.10 IPR013088 21 74 1.60e-24 Zinc finger, NHR/GATA-type
ENSMUSP00000005820 Pfam PF00104 IPR000536 170 338 3.40e-21 Nuclear hormone receptor, ligand-binding, core
ENSMUSP00000005820 Pfam PF00105 IPR001628 20 88 1.40e-27 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 PRINTS PR00047 IPR001628 21 37 3.60e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 PRINTS PR00047 IPR001628 37 52 3.60e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 PRINTS PR00047 IPR001628 70 78 3.60e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 PRINTS PR00047 IPR001628 78 86 3.60e-17 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 PRINTS PR00398 IPR001723 174 195 1.00e-18 Steroid hormone receptor
ENSMUSP00000005820 PRINTS PR00398 IPR001723 195 211 1.00e-18 Steroid hormone receptor
ENSMUSP00000005820 PRINTS PR00398 IPR001723 262 277 1.00e-18 Steroid hormone receptor
ENSMUSP00000005820 PRINTS PR00398 IPR001723 321 338 1.00e-18 Steroid hormone receptor
ENSMUSP00000005820 PRINTS PR00398 IPR001723 82 92 1.00e-18 Steroid hormone receptor
ENSMUSP00000005820 PRINTS PR00546 IPR001728 197 216 1.50e-06 Thyroid hormone receptor
ENSMUSP00000005820 PRINTS PR00546 IPR001728 262 284 1.50e-06 Thyroid hormone receptor
ENSMUSP00000005820 PRINTS PR00546 IPR001728 47 58 1.50e-06 Thyroid hormone receptor
ENSMUSP00000005820 ProSitePatterns PS00031 IPR001628 21 47 - Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 ProSiteProfiles PS51030 IPR001628 18 93 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 SMART SM00399 IPR001628 18 89 2.30e-37 Zinc finger, nuclear hormone receptor-type
ENSMUSP00000005820 SMART SM00430 IPR000536 173 333 1.80e-31 Nuclear hormone receptor, ligand-binding, core
ENSMUSP00000005820 SUPERFAMILY SSF48508 IPR008946 116 357 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000005820 PF00105 8.5e-28 zf-C4 Zinc finger, C4 type (two domains)
ENSMUSP00000005820 PF00104 2.1e-21 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000005820 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000005820 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000005820 GO:0030522 biological_process intracellular receptor signaling pathway
ENSMUSP00000005820 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSMUSP00000005820 GO:0005634 cellular_component nucleus
ENSMUSP00000005820 GO:0005737 cellular_component cytoplasm
ENSMUSP00000005820 GO:0005856 cellular_component cytoskeleton
ENSMUSP00000005820 GO:0003677 molecular_function DNA binding
ENSMUSP00000005820 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMUSP00000005820 GO:0003707 molecular_function steroid hormone receptor activity
ENSMUSP00000005820 GO:0008270 molecular_function zinc ion binding
ENSMUSP00000005820 GO:0043565 molecular_function sequence-specific DNA binding
ENSMUSP00000005820 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100768934 9555 Papio anubis 101002879
9597 Pan paniscus 100976414 39432 Saimiri boliviensis 101049831
10116 Rattus norvegicus 65035 9606 Homo sapiens 9970
9483 Callithrix jacchus ENSCJAG00000004783 10141 Cavia porcellus ENSCPOG00000015331
9796 Equus caballus ENSECAG00000020930 9365 Erinaceus europaeus ENSEEUG00000004981
30608 Microcebus murinus ENSMICG00000007296 13616 Monodelphis domestica ENSMODG00000005089
9598 Pan troglodytes ENSPTRG00000001582 9305 Sarcophilus harrisii ENSSHAG00000016687
43179 Ictidomys tridecemlineatus ENSSTOG00000003818 37347 Tupaia belangeri ENSTBEG00000000991
9615 Canis familiaris 488653 9646 Ailuropoda melanoleuca ENSAMEG00000015383
9358 Choloepus hoffmanni ENSCHOG00000008181 10020 Dipodomys ordii ENSDORG00000001701
9371 Echinops telfairi ENSETEG00000015760 9685 Felis catus ENSFCAG00000000497
9595 Gorilla gorilla ENSGGOG00000005724 9785 Loxodonta africana ENSLAFG00000001180
9315 Macropus eugenii ENSMEUG00000001987 9544 Macaca mulatta ENSMMUG00000018128
9669 Mustela putorius furo ENSMPUG00000014388 61853 Nomascus leucogenys ENSNLEG00000014287
9986 Oryctolagus cuniculus ENSOCUG00000013537 30611 Otolemur garnettii ENSOGAG00000013738
9978 Ochotona princeps ENSOPRG00000003455 9813 Procavia capensis ENSPCAG00000013933
9601 Pongo abelii ENSPPYG00000000602 132908 Pteropus vampyrus ENSPVAG00000005540
42254 Sorex araneus ENSSARG00000002684 9478 Tarsius syrichta ENSTSYG00000003712
9739 Tursiops truncatus ENSTTRG00000009227 30538 Vicugna pacos ENSVPAG00000008427
8364 Xenopus tropicalis ENSXETG00000031759