Basic Information
Gene ID 9970 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name NR1I3; CAR
Full Name Nuclear receptor subfamily 1 group I member 3
Organism Homo sapiens [9606]

Cross Reference
UniProt Q14994 UniGene Hs.349642
PDB 1XVP OMIM 603881
KEGG hsa:9970 UCSC uc001gab.3

Protein Interactions
DIP NULL
IntAct Q14994
MINT NULL
STRING 9606.ENSP00000356959

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSP00000356958 Gene3D G3DSA:1.10.565.10 IPR008946 65 356 1.10e-56 Nuclear hormone receptor, ligand-binding
ENSP00000356958 Gene3D G3DSA:3.30.50.10 IPR013088 11 64 5.40e-25 Zinc finger, NHR/GATA-type
ENSP00000356958 Pfam PF00104 IPR000536 159 334 3.20e-18 Nuclear hormone receptor, ligand-binding, core
ENSP00000356958 Pfam PF00105 IPR001628 10 78 3.90e-28 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 PRINTS PR00047 IPR001628 11 27 3.20e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 PRINTS PR00047 IPR001628 27 42 3.20e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 PRINTS PR00047 IPR001628 60 68 3.20e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 PRINTS PR00047 IPR001628 68 76 3.20e-17 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 PRINTS PR00398 IPR001723 164 185 8.20e-19 Steroid hormone receptor
ENSP00000356958 PRINTS PR00398 IPR001723 185 201 8.20e-19 Steroid hormone receptor
ENSP00000356958 PRINTS PR00398 IPR001723 256 271 8.20e-19 Steroid hormone receptor
ENSP00000356958 PRINTS PR00398 IPR001723 320 337 8.20e-19 Steroid hormone receptor
ENSP00000356958 PRINTS PR00398 IPR001723 72 82 8.20e-19 Steroid hormone receptor
ENSP00000356958 ProSitePatterns PS00031 IPR001628 11 37 - Zinc finger, nuclear hormone receptor-type
ENSP00000356958 ProSiteProfiles PS51030 IPR001628 8 83 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 SMART SM00399 IPR001628 8 79 5.60e-40 Zinc finger, nuclear hormone receptor-type
ENSP00000356958 SMART SM00430 IPR000536 163 332 1.60e-33 Nuclear hormone receptor, ligand-binding, core
ENSP00000356958 SUPERFAMILY SSF48508 IPR008946 106 356 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSP00000356958 PF00105 2.4e-28 zf-C4 Zinc finger, C4 type (two domains)
ENSP00000356958 PF00104 1.9e-18 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSP00000356958 GO:0030522 biological_process intracellular receptor signaling pathway
ENSP00000356958 GO:0005634 cellular_component nucleus
ENSP00000356958 GO:0005737 cellular_component cytoplasm
ENSP00000356958 GO:0005856 cellular_component cytoskeleton
ENSP00000356958 GO:0003677 molecular_function DNA binding
ENSP00000356958 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSP00000356958 GO:0003707 molecular_function steroid hormone receptor activity
ENSP00000356958 GO:0008270 molecular_function zinc ion binding
ENSP00000356958 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100696631 10029 Cricetulus griseus 100768934
9597 Pan paniscus 100976414 9555 Papio anubis 101002879
39432 Saimiri boliviensis 101049831 59463 Myotis lucifugus 102425669
10090 Mus musculus 12355 9615 Canis familiaris 488653
9913 Bos taurus 493713 10116 Rattus norvegicus 65035
51511 Ciona savignyi ENSCSAVG00000001918 9796 Equus caballus ENSECAG00000020930
8083 Xiphophorus maculatus ENSXMAG00000003990 28377 Anolis carolinensis ENSACAG00000013485
9646 Ailuropoda melanoleuca ENSAMEG00000015383 9358 Choloepus hoffmanni ENSCHOG00000008181
7719 Ciona intestinalis ENSCING00000020740 9483 Callithrix jacchus ENSCJAG00000004783
10141 Cavia porcellus ENSCPOG00000015331 10020 Dipodomys ordii ENSDORG00000001701
9365 Erinaceus europaeus ENSEEUG00000004981 9371 Echinops telfairi ENSETEG00000015760
9685 Felis catus ENSFCAG00000000497 69293 Gasterosteus aculeatus ENSGACG00000004763
9031 Gallus gallus ENSGALG00000026166 9595 Gorilla gorilla ENSGGOG00000005724
8049 Gadus morhua ENSGMOG00000019451 7897 Latimeria chalumnae ENSLACG00000009851
9785 Loxodonta africana ENSLAFG00000001180 9315 Macropus eugenii ENSMEUG00000001987
9103 Meleagris gallopavo ENSMGAG00000004846 30608 Microcebus murinus ENSMICG00000007296
9544 Macaca mulatta ENSMMUG00000018128 13616 Monodelphis domestica ENSMODG00000005089
9669 Mustela putorius furo ENSMPUG00000014388 61853 Nomascus leucogenys ENSNLEG00000014287
9986 Oryctolagus cuniculus ENSOCUG00000013537 30611 Otolemur garnettii ENSOGAG00000013738
9978 Ochotona princeps ENSOPRG00000003455 8090 Oryzias latipes ENSORLG00000017953
9813 Procavia capensis ENSPCAG00000013933 7757 Petromyzon marinus ENSPMAG00000000180
9601 Pongo abelii ENSPPYG00000000602 13735 Pelodiscus sinensis ENSPSIG00000004437
9598 Pan troglodytes ENSPTRG00000001582 132908 Pteropus vampyrus ENSPVAG00000005540
42254 Sorex araneus ENSSARG00000002684 9305 Sarcophilus harrisii ENSSHAG00000016687
9823 Sus scrofa ENSSSCG00000011890 43179 Ictidomys tridecemlineatus ENSSTOG00000003818
37347 Tupaia belangeri ENSTBEG00000000991 99883 Tetraodon nigroviridis ENSTNIG00000013932
31033 Takifugu rubripes ENSTRUG00000003245 9478 Tarsius syrichta ENSTSYG00000003712
9739 Tursiops truncatus ENSTTRG00000009227 30538 Vicugna pacos ENSVPAG00000008427
8364 Xenopus tropicalis ENSXETG00000018029