Basic Information
Gene ID 17131 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Smad7; Madh7, Madh8
Full Name Mothers against decapentaplegic homolog 7
Organism Mus musculus [10090]

Cross Reference
UniProt O35253 UniGene Mm.34407
PDB NULL OMIM NULL
KEGG mmu:17131 UCSC uc008fqe.2

Protein Interactions
DIP NULL
IntAct O35253
MINT MINT-261918
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000026999 Gene3D G3DSA:2.60.200.10 IPR017855 257 424 6.00e-59 SMAD domain-like
ENSMUSP00000026999 Gene3D G3DSA:3.90.520.10 IPR013019 1 27 1.80e-51 MAD homology, MH1
ENSMUSP00000026999 Gene3D G3DSA:3.90.520.10 IPR013019 91 214 1.80e-51 MAD homology, MH1
ENSMUSP00000026999 PANTHER PTHR13703 IPR013790 1 424 0.00e-00 Dwarfin
ENSMUSP00000026999 Pfam PF03165 IPR003619 93 202 2.60e-30 MAD homology 1, Dwarfin-type
ENSMUSP00000026999 Pfam PF03166 IPR001132 257 425 2.60e-62 SMAD domain, Dwarfin-type
ENSMUSP00000026999 ProSiteProfiles PS51075 IPR013019 64 207 0.00e-00 MAD homology, MH1
ENSMUSP00000026999 ProSiteProfiles PS51076 IPR001132 261 426 0.00e-00 SMAD domain, Dwarfin-type
ENSMUSP00000026999 SMART SM00523 IPR003619 87 205 1.10e-53 MAD homology 1, Dwarfin-type
ENSMUSP00000026999 SMART SM00524 IPR001132 259 424 5.00e-85 SMAD domain, Dwarfin-type
ENSMUSP00000026999 SUPERFAMILY SSF49879 IPR008984 205 424 0.00e-00 SMAD/FHA domain
ENSMUSP00000026999 SUPERFAMILY SSF56366 IPR013019 10 27 0.00e-00 MAD homology, MH1
ENSMUSP00000026999 SUPERFAMILY SSF56366 IPR013019 91 202 0.00e-00 MAD homology, MH1

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000026999 PF03166 0 MH2 MH2 domain
ENSMUSP00000026999 PF03165 1.2e-30 MH1 MH1 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000026999 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000026999 GO:0007179 biological_process transforming growth factor beta receptor signaling pathway
ENSMUSP00000026999 GO:0005634 cellular_component nucleus
ENSMUSP00000026999 GO:0005667 cellular_component transcription factor complex
ENSMUSP00000026999 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
10029 Cricetulus griseus 100758934 30611 Otolemur garnettii 100961390
39432 Saimiri boliviensis 101039142 59463 Myotis lucifugus 102427200
7029 Acyrthosiphon pisum 100169367 10224 Saccoglossus kowalevskii 100303485
9601 Pongo abelii 100460706 9823 Sus scrofa 100521305
30195 Bombus terrestris 100642241 132113 Bombus impatiens 100742914
7463 Apis florea 100865353 143995 Megachile rotundata 100880401
9597 Pan paniscus 100982938 9555 Papio anubis 101009976
8090 Oryzias latipes 101165328 9669 Mustela putorius furo 101689895
7897 Latimeria chalumnae 102346848 13735 Pelodiscus sinensis 102456346
9606 Homo sapiens 4092 7227 Drosophila melanogaster 42059
9598 Pan troglodytes 455411 9913 Bos taurus 511279
7070 Tribolium castaneum 658331 10116 Rattus norvegicus 81516
28377 Anolis carolinensis ENSACAG00000018004 9646 Ailuropoda melanoleuca ENSAMEG00000006739
9615 Canis familiaris ENSCAFG00000019069 7719 Ciona intestinalis ENSCING00000009022
9483 Callithrix jacchus ENSCJAG00000007573 10141 Cavia porcellus ENSCPOG00000021302
51511 Ciona savignyi ENSCSAVG00000011118 7955 Danio rerio ENSDARG00000016858
9361 Dasypus novemcinctus ENSDNOG00000008227 10020 Dipodomys ordii ENSDORG00000001837
9796 Equus caballus ENSECAG00000020583 9371 Echinops telfairi ENSETEG00000001041
69293 Gasterosteus aculeatus ENSGACG00000016510 9031 Gallus gallus ENSGALG00000027843
9595 Gorilla gorilla ENSGGOG00000010554 8049 Gadus morhua ENSGMOG00000003441
9785 Loxodonta africana ENSLAFG00000008013 9103 Meleagris gallopavo ENSMGAG00000009875
30608 Microcebus murinus ENSMICG00000001332 9544 Macaca mulatta ENSMMUG00000019018
13616 Monodelphis domestica ENSMODG00000003475 61853 Nomascus leucogenys ENSNLEG00000011529
9258 Ornithorhynchus anatinus ENSOANG00000007018 8128 Oreochromis niloticus ENSONIG00000007747
9978 Ochotona princeps ENSOPRG00000003587 9813 Procavia capensis ENSPCAG00000015115
7757 Petromyzon marinus ENSPMAG00000008281 132908 Pteropus vampyrus ENSPVAG00000001966
42254 Sorex araneus ENSSARG00000004025 9305 Sarcophilus harrisii ENSSHAG00000007962
43179 Ictidomys tridecemlineatus ENSSTOG00000020985 59729 Taeniopygia guttata ENSTGUG00000000033
31033 Takifugu rubripes ENSTRUG00000010212 9478 Tarsius syrichta ENSTSYG00000003256
9739 Tursiops truncatus ENSTTRG00000004362 8083 Xiphophorus maculatus ENSXMAG00000004239
7460 Apis mellifera 413371 7668 Strongylocentrotus purpuratus 593676
9685 Felis catus ENSFCAG00000025462 9315 Macropus eugenii ENSMEUG00000011322
9986 Oryctolagus cuniculus ENSOCUG00000006134 99883 Tetraodon nigroviridis ENSTNIG00000018764
8364 Xenopus tropicalis ENSXETG00000020317