Basic Information
Gene ID 20681 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Sox8; Sox-8
Full Name Transcription factor SOX-8
Organism Mus musculus [10090]

Cross Reference
UniProt Q04886 UniGene Mm.258220
PDB NULL OMIM NULL
KEGG mmu:20681 UCSC uc008bay.1

Protein Interactions
DIP NULL
IntAct Q04886
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMUSP00000025003 Gene3D G3DSA:1.10.30.10 IPR009071 97 177 1.40e-34 High mobility group box domain
ENSMUSP00000025003 Pfam PF00505 IPR009071 99 167 3.00e-25 High mobility group box domain
ENSMUSP00000025003 Pfam PF12444 IPR022151 5 86 1.10e-21 Sox developmental protein N-terminal
ENSMUSP00000025003 ProSiteProfiles PS50118 IPR009071 99 167 0.00e-00 High mobility group box domain
ENSMUSP00000025003 SMART SM00398 IPR009071 98 168 1.30e-30 High mobility group box domain
ENSMUSP00000025003 SUPERFAMILY SSF47095 IPR009071 83 171 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMUSP00000025003 PF00505 1.9e-25 HMG_box HMG (high mobility group) box
ENSMUSP00000025003 PF12444 1.1e-21 Sox_N Sox developmental protein N terminal
ENSMUSP00000025003 PF09011 4.5e-11 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMUSP00000025003 GO:0006351 biological_process transcription, DNA-templated
ENSMUSP00000025003 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMUSP00000025003 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMUSP00000025003 GO:0051216 biological_process cartilage development
ENSMUSP00000025003 GO:0005634 cellular_component nucleus
ENSMUSP00000025003 GO:0003677 molecular_function DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100121326 6087 Hydra magnipapillata 100201982
10224 Saccoglossus kowalevskii 100367276 9483 Callithrix jacchus 100406753
9601 Pongo abelii 100452528 7029 Acyrthosiphon pisum 100572600
61853 Nomascus leucogenys 100594481 400682 Amphimedon queenslandica 100631786
30195 Bombus terrestris 100649595 132113 Bombus impatiens 100745991
143995 Megachile rotundata 100874890 34638 Metaseiulus occidentalis 100903070
9305 Sarcophilus harrisii 100927839 9597 Pan paniscus 100982478
9555 Papio anubis 101005143 39432 Saimiri boliviensis 101051303
9595 Gorilla gorilla 101138924 8083 Xiphophorus maculatus 102229521
13616 Monodelphis domestica 100021633 8128 Oreochromis niloticus 100698682
10029 Cricetulus griseus 100774670 7463 Apis florea 100865797
59463 Myotis lucifugus 102431224 28377 Anolis carolinensis ENSACAG00000006111
9646 Ailuropoda melanoleuca ENSAMEG00000007508 9615 Canis familiaris ENSCAFG00000019601
8049 Gadus morhua ENSGMOG00000009261 7897 Latimeria chalumnae ENSLACG00000016616
9986 Oryctolagus cuniculus ENSOCUG00000011639 8090 Oryzias latipes ENSORLG00000007994
9598 Pan troglodytes ENSPTRG00000007570 31033 Takifugu rubripes ENSTRUG00000009225
10116 Rattus norvegicus 302993 7227 Drosophila melanogaster 45039
7668 Strongylocentrotus purpuratus 581729 7460 Apis mellifera 727284
9913 Bos taurus ENSBTAG00000020737 7719 Ciona intestinalis ENSCING00000001019
10141 Cavia porcellus ENSCPOG00000002664 51511 Ciona savignyi ENSCSAVG00000008424
7955 Danio rerio ENSDARG00000068019 10020 Dipodomys ordii ENSDORG00000012440
9796 Equus caballus ENSECAG00000016320 9365 Erinaceus europaeus ENSEEUG00000011263
9371 Echinops telfairi ENSETEG00000015470 9685 Felis catus ENSFCAG00000004219
69293 Gasterosteus aculeatus ENSGACG00000011207 9031 Gallus gallus ENSGALG00000005263
9785 Loxodonta africana ENSLAFG00000010824 9315 Macropus eugenii ENSMEUG00000004922
9103 Meleagris gallopavo ENSMGAG00000005341 30608 Microcebus murinus ENSMICG00000011516
9544 Macaca mulatta ENSMMUG00000002412 9669 Mustela putorius furo ENSMPUG00000015893
9258 Ornithorhynchus anatinus ENSOANG00000003894 30611 Otolemur garnettii ENSOGAG00000007992
9978 Ochotona princeps ENSOPRG00000007860 9813 Procavia capensis ENSPCAG00000012287
7757 Petromyzon marinus ENSPMAG00000006957 13735 Pelodiscus sinensis ENSPSIG00000007448
132908 Pteropus vampyrus ENSPVAG00000014806 9823 Sus scrofa ENSSSCG00000017251
43179 Ictidomys tridecemlineatus ENSSTOG00000008722 37347 Tupaia belangeri ENSTBEG00000000175
59729 Taeniopygia guttata ENSTGUG00000006856 99883 Tetraodon nigroviridis ENSTNIG00000009756
9478 Tarsius syrichta ENSTSYG00000006321 9739 Tursiops truncatus ENSTTRG00000005687
30538 Vicugna pacos ENSVPAG00000000908 8364 Xenopus tropicalis ENSXETG00000005746