Basic Information
Gene ID 30501
Gene Name otx2
Full Name Homeobox protein OTX2
Organism Danio rerio [7955]

Cross Reference
UniProt Q91981 UniGene Dr.334
PDB NULL OMIM NULL
KEGG dre:30501 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
REFSEQ
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSDARP00000020202 Gene3D G3DSA:1.10.10.60 IPR009057 34 102 7.00e-27 Homeodomain-like
ENSDARP00000020202 Pfam PF00046 IPR001356 39 95 8.30e-22 Homeobox domain
ENSDARP00000020202 Pfam PF03529 IPR013851 153 235 7.60e-37 Transcription factor Otx, C-terminal
ENSDARP00000020202 PRINTS PR01255 IPR003025 1 10 6.30e-13 Transcription factor Otx
ENSDARP00000020202 PRINTS PR01255 IPR003025 175 181 6.30e-13 Transcription factor Otx
ENSDARP00000020202 PRINTS PR01255 IPR003025 195 203 6.30e-13 Transcription factor Otx
ENSDARP00000020202 PRINTS PR01255 IPR003025 255 261 6.30e-13 Transcription factor Otx
ENSDARP00000020202 PRINTS PR01257 IPR003022 15 21 5.80e-14 Transcription factor Otx2
ENSDARP00000020202 PRINTS PR01257 IPR003022 159 168 5.80e-14 Transcription factor Otx2
ENSDARP00000020202 PRINTS PR01257 IPR003022 178 184 5.80e-14 Transcription factor Otx2
ENSDARP00000020202 PRINTS PR01257 IPR003022 230 239 5.80e-14 Transcription factor Otx2
ENSDARP00000020202 ProSitePatterns PS00027 IPR017970 71 94 - Homeobox, conserved site
ENSDARP00000020202 ProSiteProfiles PS50071 IPR001356 36 96 0.00e-00 Homeobox domain
ENSDARP00000020202 SMART SM00389 IPR001356 38 100 4.00e-27 Homeobox domain
ENSDARP00000020202 SUPERFAMILY SSF46689 IPR009057 16 98 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSDARP00000020202 PF03529 7.6e-37 TF_Otx Otx1 transcription factor
ENSDARP00000020202 PF00046 5.3e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSDARP00000020202 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSDARP00000020202 GO:0007275 biological_process multicellular organismal development
ENSDARP00000020202 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSDARP00000020202 GO:0005634 cellular_component nucleus
ENSDARP00000020202 GO:0003677 molecular_function DNA binding
ENSDARP00000020202 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSDARP00000020202 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
6087 Hydra magnipapillata 100209084 10224 Saccoglossus kowalevskii 100302712
9785 Loxodonta africana 100666163 8128 Oreochromis niloticus 100707476
10029 Cricetulus griseus 100764947 143995 Megachile rotundata 100877036
39432 Saimiri boliviensis 101029683 9595 Gorilla gorilla 101135739
9669 Mustela putorius furo 101677421 10090 Mus musculus 18424
9986 Oryctolagus cuniculus 100009374 9796 Equus caballus 100050678
7029 Acyrthosiphon pisum 100169486 9646 Ailuropoda melanoleuca 100467291
34638 Metaseiulus occidentalis 100905820 9305 Sarcophilus harrisii 100925398
9597 Pan paniscus 100983632 9555 Papio anubis 101007811
43179 Ictidomys tridecemlineatus 101960358 8083 Xiphophorus maculatus 102228797
13735 Pelodiscus sinensis 102450003 6239 Caenorhabditis elegans 181530
9031 Gallus gallus 395191 9606 Homo sapiens 5015
7070 Tribolium castaneum 641604 9358 Choloepus hoffmanni ENSCHOG00000013827
10141 Cavia porcellus ENSCPOG00000003420 51511 Ciona savignyi ENSCSAVG00000009682
9371 Echinops telfairi ENSETEG00000014047 69293 Gasterosteus aculeatus ENSGACG00000012744
8049 Gadus morhua ENSGMOG00000016352 7897 Latimeria chalumnae ENSLACG00000018973
9315 Macropus eugenii ENSMEUG00000000827 30608 Microcebus murinus ENSMICG00000017005
61853 Nomascus leucogenys ENSNLEG00000012999 30611 Otolemur garnettii ENSOGAG00000006981
8090 Oryzias latipes ENSORLG00000016191 9813 Procavia capensis ENSPCAG00000009289
42254 Sorex araneus ENSSARG00000007709 37347 Tupaia belangeri ENSTBEG00000002550
99883 Tetraodon nigroviridis ENSTNIG00000017380 31033 Takifugu rubripes ENSTRUG00000018137
9739 Tursiops truncatus ENSTTRG00000004650 7668 Strongylocentrotus purpuratus 373400
9615 Canis familiaris 610347 9598 Pan troglodytes 744025
28377 Anolis carolinensis ENSACAG00000008544 9483 Callithrix jacchus ENSCJAG00000018583
10020 Dipodomys ordii ENSDORG00000002219 9365 Erinaceus europaeus ENSEEUG00000015763
9685 Felis catus ENSFCAG00000024521 9103 Meleagris gallopavo ENSMGAG00000013637
59463 Myotis lucifugus ENSMLUG00000022591 9544 Macaca mulatta ENSMMUG00000002425
13616 Monodelphis domestica ENSMODG00000003035 9978 Ochotona princeps ENSOPRG00000015946
7757 Petromyzon marinus ENSPMAG00000001190 9601 Pongo abelii ENSPPYG00000005846
132908 Pteropus vampyrus ENSPVAG00000001624 10116 Rattus norvegicus ENSRNOG00000008756
59729 Taeniopygia guttata ENSTGUG00000013055 9478 Tarsius syrichta ENSTSYG00000006803
30538 Vicugna pacos ENSVPAG00000002702

Paralogs
ENSDARG00000043483