Basic Information
Gene ID ENSLACG00000018973
Gene Name OTX2
Full Name Uncharacterized protein
Organism Latimeria chalumnae [7897]

Cross Reference
UniProt H3BI73 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLACP00000021594 Gene3D G3DSA:1.10.10.60 IPR009057 53 121 7.80e-27 Homeodomain-like
ENSLACP00000021594 Pfam PF00046 IPR001356 58 114 9.20e-22 Homeobox domain
ENSLACP00000021594 Pfam PF03529 IPR013851 172 254 9.50e-37 Transcription factor Otx, C-terminal
ENSLACP00000021594 PRINTS PR01255 IPR003025 194 200 9.20e-13 Transcription factor Otx
ENSLACP00000021594 PRINTS PR01255 IPR003025 20 29 9.20e-13 Transcription factor Otx
ENSLACP00000021594 PRINTS PR01255 IPR003025 214 222 9.20e-13 Transcription factor Otx
ENSLACP00000021594 PRINTS PR01255 IPR003025 274 280 9.20e-13 Transcription factor Otx
ENSLACP00000021594 PRINTS PR01257 IPR003022 178 187 5.30e-13 Transcription factor Otx2
ENSLACP00000021594 PRINTS PR01257 IPR003022 197 203 5.30e-13 Transcription factor Otx2
ENSLACP00000021594 PRINTS PR01257 IPR003022 249 258 5.30e-13 Transcription factor Otx2
ENSLACP00000021594 PRINTS PR01257 IPR003022 34 40 5.30e-13 Transcription factor Otx2
ENSLACP00000021594 ProSitePatterns PS00027 IPR017970 90 113 - Homeobox, conserved site
ENSLACP00000021594 ProSiteProfiles PS50071 IPR001356 55 115 0.00e-00 Homeobox domain
ENSLACP00000021594 SMART SM00389 IPR001356 57 119 4.00e-27 Homeobox domain
ENSLACP00000021594 SUPERFAMILY SSF46689 IPR009057 35 117 0.00e-00 Homeodomain-like

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLACP00000021594 PF03529 9.5e-37 TF_Otx Otx1 transcription factor
ENSLACP00000021594 PF00046 5.7e-22 Homeobox Homeobox domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLACP00000021594 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSLACP00000021594 GO:0007275 biological_process multicellular organismal development
ENSLACP00000021594 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSLACP00000021594 GO:0005634 cellular_component nucleus
ENSLACP00000021594 GO:0003677 molecular_function DNA binding
ENSLACP00000021594 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLACP00000021594 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100009374 9796 Equus caballus 100050678
10224 Saccoglossus kowalevskii 100302712 9646 Ailuropoda melanoleuca 100467291
9785 Loxodonta africana 100666163 8128 Oreochromis niloticus 100707476
9597 Pan paniscus 100983632 9555 Papio anubis 101007811
39432 Saimiri boliviensis 101029683 9595 Gorilla gorilla 101135739
9669 Mustela putorius furo 101677421 43179 Ictidomys tridecemlineatus 101960358
8083 Xiphophorus maculatus 102228797 13735 Pelodiscus sinensis 102450003
6239 Caenorhabditis elegans 181530 10090 Mus musculus 18424
7955 Danio rerio 30501 7668 Strongylocentrotus purpuratus 373400
9606 Homo sapiens 5015 28377 Anolis carolinensis ENSACAG00000008544
9483 Callithrix jacchus ENSCJAG00000018583 10141 Cavia porcellus ENSCPOG00000003420
10020 Dipodomys ordii ENSDORG00000002219 9365 Erinaceus europaeus ENSEEUG00000015763
9371 Echinops telfairi ENSETEG00000014047 9685 Felis catus ENSFCAG00000024521
69293 Gasterosteus aculeatus ENSGACG00000012744 8049 Gadus morhua ENSGMOG00000016352
34638 Metaseiulus occidentalis 100905820 9031 Gallus gallus 395191
9358 Choloepus hoffmanni ENSCHOG00000013827 9315 Macropus eugenii ENSMEUG00000000827
30611 Otolemur garnettii ENSOGAG00000006981 9739 Tursiops truncatus ENSTTRG00000004650
9103 Meleagris gallopavo ENSMGAG00000013637 30608 Microcebus murinus ENSMICG00000017005
59463 Myotis lucifugus ENSMLUG00000022591 9544 Macaca mulatta ENSMMUG00000002425
61853 Nomascus leucogenys ENSNLEG00000012999 9978 Ochotona princeps ENSOPRG00000015946
8090 Oryzias latipes ENSORLG00000016191 9813 Procavia capensis ENSPCAG00000009289
9601 Pongo abelii ENSPPYG00000005846 132908 Pteropus vampyrus ENSPVAG00000001624
42254 Sorex araneus ENSSARG00000007709 37347 Tupaia belangeri ENSTBEG00000002550
59729 Taeniopygia guttata ENSTGUG00000013055 99883 Tetraodon nigroviridis ENSTNIG00000017380
31033 Takifugu rubripes ENSTRUG00000018137 9478 Tarsius syrichta ENSTSYG00000006803
30538 Vicugna pacos ENSVPAG00000002702

Paralogs
ENSLACG00000012436