Basic Information
Gene ID ENSACAG00000016766
Gene Name HIF3A
Full Name Uncharacterized protein
Organism Anolis carolinensis [28377]

Cross Reference
UniProt H9GNK2 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSACAP00000016495 Pfam PF11413 IPR021537 489 517 4.20e-14 Hypoxia-inducible factor, alpha subunit
ENSACAP00000016495 ProSiteProfiles PS50112 IPR000014 116 144 0.00e-00 PAS domain
ENSACAP00000016495 ProSiteProfiles PS50112 IPR000014 248 297 0.00e-00 PAS domain
ENSACAP00000016495 ProSiteProfiles PS50888 IPR011598 12 65 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016495 SMART SM00086 IPR001610 301 344 2.50e-07 PAC motif
ENSACAP00000016495 SMART SM00091 IPR000014 229 295 1.90e-07 PAS domain
ENSACAP00000016495 SMART SM00091 IPR000014 81 149 2.20e-02 PAS domain
ENSACAP00000016495 SMART SM00353 IPR011598 18 73 4.50e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016495 SUPERFAMILY SSF47459 IPR011598 10 74 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016495 SUPERFAMILY SSF55785 IPR000014 111 146 0.00e-00 PAS domain
ENSACAP00000016495 SUPERFAMILY SSF55785 IPR000014 241 341 0.00e-00 PAS domain
ENSACAP00000016495 TIGRFAM TIGR00229 IPR000014 250 328 4.90e-07 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSACAP00000016495 PF14598 5.6e-23 PAS_11 PAS domain
ENSACAP00000016495 PF08447 7.5e-21 PAS_3 PAS fold
ENSACAP00000016495 PF11413 2.1e-14 HIF-1 Hypoxia-inducible factor-1
ENSACAP00000016495 PF00989 6e-11 PAS PAS fold
ENSACAP00000016495 PF13426 2.2e-07 PAS_9 PAS domain
ENSACAP00000016495 PF08448 3.9e-05 PAS_4 PAS fold

Gene Ontology Annotation
Protein Entry Name Space Description
ENSACAP00000016495 GO:0001666 biological_process response to hypoxia
ENSACAP00000016495 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSACAP00000016495 GO:0071456 biological_process cellular response to hypoxia
ENSACAP00000016495 GO:0005634 cellular_component nucleus
ENSACAP00000016495 GO:0005737 cellular_component cytoplasm
ENSACAP00000016495 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSACAP00000016495 GO:0004871 molecular_function signal transducer activity
ENSACAP00000016495 GO:0035035 molecular_function histone acetyltransferase binding
ENSACAP00000016495 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
61853 Nomascus leucogenys 100582446 9597 Pan paniscus 100979253
9598 Pan troglodytes 456149 9555 Papio anubis 101007659
39432 Saimiri boliviensis 101027930 9595 Gorilla gorilla 101146641
43179 Ictidomys tridecemlineatus 101976940 10090 Mus musculus 53417
9606 Homo sapiens 64344 9646 Ailuropoda melanoleuca ENSAMEG00000008615
10141 Cavia porcellus ENSCPOG00000024199 9685 Felis catus ENSFCAG00000014181
59463 Myotis lucifugus ENSMLUG00000014423 9669 Mustela putorius furo ENSMPUG00000005285
9813 Procavia capensis ENSPCAG00000006067 9601 Pongo abelii ENSPPYG00000010147
10116 Rattus norvegicus ENSRNOG00000017198 9823 Sus scrofa ENSSSCG00000003101
37347 Tupaia belangeri ENSTBEG00000002129 9796 Equus caballus ENSECAG00000020693
9785 Loxodonta africana ENSLAFG00000017230 9315 Macropus eugenii ENSMEUG00000002474
30611 Otolemur garnettii ENSOGAG00000008187 132908 Pteropus vampyrus ENSPVAG00000003553
9305 Sarcophilus harrisii ENSSHAG00000004128 9739 Tursiops truncatus ENSTTRG00000001609