Basic Information
Gene ID ENSGACG00000008607
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Gasterosteus aculeatus [69293]

Cross Reference
UniProt G3P1B5 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSGACP00000011388 Gene3D G3DSA:1.10.238.10 IPR011992 468 589 3.80e-59 EF-hand domain pair
ENSGACP00000011388 Gene3D G3DSA:1.10.532.10 IPR013799 1 120 4.20e-45 STAT transcription factor, protein interaction
ENSGACP00000011388 Gene3D G3DSA:1.20.1050.20 IPR013800 138 322 1.10e-67 STAT transcription factor, all-alpha
ENSGACP00000011388 Gene3D G3DSA:2.60.40.630 IPR012345 323 467 4.50e-65 STAT transcription factor, DNA-binding, subdomain
ENSGACP00000011388 Gene3D G3DSA:3.30.505.10 IPR000980 590 719 2.60e-50 SH2 domain
ENSGACP00000011388 PANTHER PTHR11801 IPR001217 2 800 0.00e-00 Transcription factor STAT
ENSGACP00000011388 Pfam PF00017 IPR000980 585 675 1.00e-12 SH2 domain
ENSGACP00000011388 Pfam PF01017 IPR013800 138 320 8.10e-62 STAT transcription factor, all-alpha
ENSGACP00000011388 Pfam PF02864 IPR013801 322 575 1.30e-127 STAT transcription factor, DNA-binding
ENSGACP00000011388 Pfam PF02865 IPR013799 2 121 1.20e-40 STAT transcription factor, protein interaction
ENSGACP00000011388 ProSiteProfiles PS50001 IPR000980 581 671 0.00e-00 SH2 domain
ENSGACP00000011388 SMART SM00252 IPR000980 583 664 3.70e-03 SH2 domain
ENSGACP00000011388 SMART SM00964 IPR013799 2 122 1.60e-62 STAT transcription factor, protein interaction
ENSGACP00000011388 SUPERFAMILY SSF47655 IPR015988 135 322 0.00e-00 STAT transcription factor, coiled coil
ENSGACP00000011388 SUPERFAMILY SSF48092 IPR013799 1 120 0.00e-00 STAT transcription factor, protein interaction
ENSGACP00000011388 SUPERFAMILY SSF49417 IPR008967 323 576 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSGACP00000011388 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSGACP00000011388 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSGACP00000011388 PF02865 1.2e-40 STAT_int STAT protein, protein interaction domain
ENSGACP00000011388 PF00017 4.5e-13 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSGACP00000011388 GO:0001659 biological_process temperature homeostasis
ENSGACP00000011388 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSGACP00000011388 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSGACP00000011388 GO:0019953 biological_process sexual reproduction
ENSGACP00000011388 GO:0042593 biological_process glucose homeostasis
ENSGACP00000011388 GO:0042755 biological_process eating behavior
ENSGACP00000011388 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSGACP00000011388 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSGACP00000011388 GO:0005634 cellular_component nucleus
ENSGACP00000011388 GO:0005737 cellular_component cytoplasm
ENSGACP00000011388 GO:0005886 cellular_component plasma membrane
ENSGACP00000011388 GO:0003677 molecular_function DNA binding
ENSGACP00000011388 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSGACP00000011388 GO:0004871 molecular_function signal transducer activity
ENSGACP00000011388 GO:0005509 molecular_function calcium ion binding
ENSGACP00000011388 GO:0019901 molecular_function protein kinase binding
ENSGACP00000011388 GO:0043565 molecular_function sequence-specific DNA binding
ENSGACP00000011388 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9615 Canis familiaris 490967 28377 Anolis carolinensis ENSACAG00000017940
9483 Callithrix jacchus ENSCJAG00000000409 9986 Oryctolagus cuniculus 100348778
10029 Cricetulus griseus 100755865 9597 Pan paniscus 100987766
9555 Papio anubis 100998929 39432 Saimiri boliviensis 101049662
31033 Takifugu rubripes 101070968 9685 Felis catus 101095698
8083 Xiphophorus maculatus 102226045 9646 Ailuropoda melanoleuca ENSAMEG00000006266
9358 Choloepus hoffmanni ENSCHOG00000009349 10141 Cavia porcellus ENSCPOG00000007939
9361 Dasypus novemcinctus ENSDNOG00000001471 10020 Dipodomys ordii ENSDORG00000000308
9796 Equus caballus ENSECAG00000016439 9595 Gorilla gorilla ENSGGOG00000017110
8049 Gadus morhua ENSGMOG00000014955 7897 Latimeria chalumnae ENSLACG00000012019
9315 Macropus eugenii ENSMEUG00000006663 9103 Meleagris gallopavo ENSMGAG00000003545
30608 Microcebus murinus ENSMICG00000012015 59463 Myotis lucifugus ENSMLUG00000017449
13616 Monodelphis domestica ENSMODG00000028212 9669 Mustela putorius furo ENSMPUG00000010509
30611 Otolemur garnettii ENSOGAG00000001517 8128 Oreochromis niloticus ENSONIG00000001148
8090 Oryzias latipes ENSORLG00000004061 9813 Procavia capensis ENSPCAG00000006029
9601 Pongo abelii ENSPPYG00000008392 13735 Pelodiscus sinensis ENSPSIG00000015868
132908 Pteropus vampyrus ENSPVAG00000003885 42254 Sorex araneus ENSSARG00000014231
9305 Sarcophilus harrisii ENSSHAG00000014833 43179 Ictidomys tridecemlineatus ENSSTOG00000006741
9478 Tarsius syrichta ENSTSYG00000012448 9739 Tursiops truncatus ENSTTRG00000007163
9785 Loxodonta africana ENSLAFG00000014062 9544 Macaca mulatta ENSMMUG00000010707
9978 Ochotona princeps ENSOPRG00000008362 7757 Petromyzon marinus ENSPMAG00000002770
59729 Taeniopygia guttata ENSTGUG00000002600 8364 Xenopus tropicalis ENSXETG00000007642