Basic Information
Gene ID ENSPMAG00000002770
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Petromyzon marinus [7757]

Cross Reference
UniProt S4RD74 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSPMAP00000003156 Gene3D G3DSA:1.10.238.10 IPR011992 462 583 2.40e-54 EF-hand domain pair
ENSPMAP00000003156 Gene3D G3DSA:1.10.532.10 IPR013799 1 121 2.10e-45 STAT transcription factor, protein interaction
ENSPMAP00000003156 Gene3D G3DSA:1.20.1050.20 IPR013800 140 318 6.20e-59 STAT transcription factor, all-alpha
ENSPMAP00000003156 Gene3D G3DSA:2.60.40.630 IPR012345 319 461 1.90e-61 STAT transcription factor, DNA-binding, subdomain
ENSPMAP00000003156 Gene3D G3DSA:3.30.505.10 IPR000980 584 715 1.30e-48 SH2 domain
ENSPMAP00000003156 PANTHER PTHR11801 IPR001217 2 723 0.00e-00 Transcription factor STAT
ENSPMAP00000003156 Pfam PF00017 IPR000980 580 646 4.30e-10 SH2 domain
ENSPMAP00000003156 Pfam PF01017 IPR013800 139 316 7.70e-57 STAT transcription factor, all-alpha
ENSPMAP00000003156 Pfam PF02864 IPR013801 318 569 2.10e-118 STAT transcription factor, DNA-binding
ENSPMAP00000003156 Pfam PF02865 IPR013799 2 121 1.20e-42 STAT transcription factor, protein interaction
ENSPMAP00000003156 ProSiteProfiles PS50001 IPR000980 575 676 0.00e-00 SH2 domain
ENSPMAP00000003156 SMART SM00252 IPR000980 577 663 1.10e-03 SH2 domain
ENSPMAP00000003156 SMART SM00964 IPR013799 2 122 8.10e-63 STAT transcription factor, protein interaction
ENSPMAP00000003156 SUPERFAMILY SSF47655 IPR015988 140 318 0.00e-00 STAT transcription factor, coiled coil
ENSPMAP00000003156 SUPERFAMILY SSF48092 IPR013799 1 121 0.00e-00 STAT transcription factor, protein interaction
ENSPMAP00000003156 SUPERFAMILY SSF49417 IPR008967 319 570 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSPMAP00000003156 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSPMAP00000003156 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSPMAP00000003156 PF02865 1.19951e-42 STAT_int STAT protein, protein interaction domain
ENSPMAP00000003156 PF00017 7.9e-11 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSPMAP00000003156 GO:0001659 biological_process temperature homeostasis
ENSPMAP00000003156 GO:0001754 biological_process eye photoreceptor cell differentiation
ENSPMAP00000003156 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSPMAP00000003156 GO:0019953 biological_process sexual reproduction
ENSPMAP00000003156 GO:0042593 biological_process glucose homeostasis
ENSPMAP00000003156 GO:0042755 biological_process eating behavior
ENSPMAP00000003156 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSPMAP00000003156 GO:0060397 biological_process JAK-STAT cascade involved in growth hormone signaling pathway
ENSPMAP00000003156 GO:0005634 cellular_component nucleus
ENSPMAP00000003156 GO:0005737 cellular_component cytoplasm
ENSPMAP00000003156 GO:0005886 cellular_component plasma membrane
ENSPMAP00000003156 GO:0003677 molecular_function DNA binding
ENSPMAP00000003156 GO:0004871 molecular_function signal transducer activity
ENSPMAP00000003156 GO:0005509 molecular_function calcium ion binding
ENSPMAP00000003156 GO:0019901 molecular_function protein kinase binding
ENSPMAP00000003156 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7955 Danio rerio ENSDARG00000006266 10029 Cricetulus griseus 100755609
9597 Pan paniscus 100971620 9555 Papio anubis 101005886
39432 Saimiri boliviensis 101030811 31033 Takifugu rubripes 101070968
8083 Xiphophorus maculatus 102226045 7897 Latimeria chalumnae 102353760
13735 Pelodiscus sinensis 102462741 10090 Mus musculus 20849
10116 Rattus norvegicus 25124 9615 Canis familiaris 490967
9913 Bos taurus 510814 9544 Macaca mulatta 693650
28377 Anolis carolinensis ENSACAG00000017940 9646 Ailuropoda melanoleuca ENSAMEG00000006266
10141 Cavia porcellus ENSCPOG00000007939 9361 Dasypus novemcinctus ENSDNOG00000001471
9796 Equus caballus ENSECAG00000009039 9371 Echinops telfairi ENSETEG00000017040
9685 Felis catus ENSFCAG00000013725 69293 Gasterosteus aculeatus ENSGACG00000008607
9031 Gallus gallus ENSGALG00000007651 9595 Gorilla gorilla ENSGGOG00000000611
8049 Gadus morhua ENSGMOG00000014955 9785 Loxodonta africana ENSLAFG00000001475
9315 Macropus eugenii ENSMEUG00000012165 9103 Meleagris gallopavo ENSMGAG00000006382
30608 Microcebus murinus ENSMICG00000002941 59463 Myotis lucifugus ENSMLUG00000017449
13616 Monodelphis domestica ENSMODG00000011747 9669 Mustela putorius furo ENSMPUG00000012530
61853 Nomascus leucogenys ENSNLEG00000006694 9986 Oryctolagus cuniculus ENSOCUG00000002455
30611 Otolemur garnettii ENSOGAG00000003038 8128 Oreochromis niloticus ENSONIG00000001148
9978 Ochotona princeps ENSOPRG00000008589 8090 Oryzias latipes ENSORLG00000004061
9813 Procavia capensis ENSPCAG00000007855 9601 Pongo abelii ENSPPYG00000013027
9598 Pan troglodytes ENSPTRG00000012749 132908 Pteropus vampyrus ENSPVAG00000003885
42254 Sorex araneus ENSSARG00000014231 9823 Sus scrofa ENSSSCG00000016057
43179 Ictidomys tridecemlineatus ENSSTOG00000008620 37347 Tupaia belangeri ENSTBEG00000017412
59729 Taeniopygia guttata ENSTGUG00000002600 99883 Tetraodon nigroviridis ENSTNIG00000017161
9478 Tarsius syrichta ENSTSYG00000012448 9739 Tursiops truncatus ENSTTRG00000007163
8364 Xenopus tropicalis ENSXETG00000004649 9305 Sarcophilus harrisii ENSSHAG00000016913