Basic Information
Gene ID ENSLAFG00000015250
Gene Name LOC100677316
Full Name Uncharacterized protein
Organism Loxodonta africana [9785]

Cross Reference
UniProt G3TES0 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSLAFP00000012768 Gene3D G3DSA:1.10.565.10 IPR008946 2 185 5.80e-66 Nuclear hormone receptor, ligand-binding
ENSLAFP00000012768 Pfam PF00104 IPR000536 2 161 1.30e-22 Nuclear hormone receptor, ligand-binding, core
ENSLAFP00000012768 Pfam PF12743 IPR024736 189 232 5.60e-22 Oestrogen-type nuclear receptor final C-terminal domain
ENSLAFP00000012768 PRINTS PR00398 IPR001723 143 160 7.40e-15 Steroid hormone receptor
ENSLAFP00000012768 PRINTS PR00398 IPR001723 7 23 7.40e-15 Steroid hormone receptor
ENSLAFP00000012768 PRINTS PR00398 IPR001723 75 90 7.40e-15 Steroid hormone receptor
ENSLAFP00000012768 SMART SM00430 IPR000536 2 155 3.60e-22 Nuclear hormone receptor, ligand-binding, core
ENSLAFP00000012768 SUPERFAMILY SSF48508 IPR008946 2 184 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSLAFP00000012768 PF00104 9.3e-23 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSLAFP00000012768 PF12743 3.7e-22 ESR1_C Oestrogen-type nuclear receptor final C-terminal

Gene Ontology Annotation
Protein Entry Name Space Description
ENSLAFP00000012768 GO:0006351 biological_process transcription, DNA-templated
ENSLAFP00000012768 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSLAFP00000012768 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
ENSLAFP00000012768 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
ENSLAFP00000012768 GO:0010863 biological_process positive regulation of phospholipase C activity
ENSLAFP00000012768 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
ENSLAFP00000012768 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
ENSLAFP00000012768 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
ENSLAFP00000012768 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
ENSLAFP00000012768 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
ENSLAFP00000012768 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSLAFP00000012768 GO:0071392 biological_process cellular response to estradiol stimulus
ENSLAFP00000012768 GO:0005634 cellular_component nucleus
ENSLAFP00000012768 GO:0005794 cellular_component Golgi apparatus
ENSLAFP00000012768 GO:0005886 cellular_component plasma membrane
ENSLAFP00000012768 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSLAFP00000012768 GO:0003707 molecular_function steroid hormone receptor activity
ENSLAFP00000012768 GO:0005496 molecular_function steroid binding
ENSLAFP00000012768 GO:0008270 molecular_function zinc ion binding
ENSLAFP00000012768 GO:0030284 molecular_function estrogen receptor activity
ENSLAFP00000012768 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100385918 39432 Saimiri boliviensis 101034130
9365 Erinaceus europaeus ENSEEUG00000000828 9371 Echinops telfairi ENSETEG00000006131
30608 Microcebus murinus ENSMICG00000007592 9258 Ornithorhynchus anatinus ENSOANG00000015561
9823 Sus scrofa ENSSSCG00000025777 37347 Tupaia belangeri ENSTBEG00000005946