Basic Information
Gene ID ENSSSCG00000025777
Gene Name ESR1
Full Name Estrogen receptor
Organism Sus scrofa [9823]

Cross Reference
UniProt D9UC10 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSSCP00000030835 Gene3D G3DSA:1.10.565.10 IPR008946 4 137 8.30e-44 Nuclear hormone receptor, ligand-binding
ENSSSCP00000030835 Pfam PF00104 IPR000536 8 117 8.30e-08 Nuclear hormone receptor, ligand-binding, core
ENSSSCP00000030835 Pfam PF12743 IPR024736 141 184 5.70e-22 Oestrogen-type nuclear receptor final C-terminal domain
ENSSSCP00000030835 PRINTS PR00398 IPR001723 27 42 1.20e-06 Steroid hormone receptor
ENSSSCP00000030835 PRINTS PR00398 IPR001723 95 112 1.20e-06 Steroid hormone receptor
ENSSSCP00000030835 SUPERFAMILY SSF48508 IPR008946 2 136 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSSCP00000030835 PF12743 3.9e-22 ESR1_C Oestrogen-type nuclear receptor final C-terminal
ENSSSCP00000030835 PF00104 5.8e-08 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSSCP00000030835 GO:0006351 biological_process transcription, DNA-templated
ENSSSCP00000030835 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSSCP00000030835 GO:0007200 biological_process phospholipase C-activating G-protein coupled receptor signaling pathway
ENSSSCP00000030835 GO:0007204 biological_process positive regulation of cytosolic calcium ion concentration
ENSSSCP00000030835 GO:0010863 biological_process positive regulation of phospholipase C activity
ENSSSCP00000030835 GO:0030518 biological_process intracellular steroid hormone receptor signaling pathway
ENSSSCP00000030835 GO:0043124 biological_process negative regulation of I-kappaB kinase/NF-kappaB signaling
ENSSSCP00000030835 GO:0043433 biological_process negative regulation of sequence-specific DNA binding transcription factor activity
ENSSSCP00000030835 GO:0045429 biological_process positive regulation of nitric oxide biosynthetic process
ENSSSCP00000030835 GO:0051000 biological_process positive regulation of nitric-oxide synthase activity
ENSSSCP00000030835 GO:0051091 biological_process positive regulation of sequence-specific DNA binding transcription factor activity
ENSSSCP00000030835 GO:0071392 biological_process cellular response to estradiol stimulus
ENSSSCP00000030835 GO:0005634 cellular_component nucleus
ENSSSCP00000030835 GO:0005794 cellular_component Golgi apparatus
ENSSSCP00000030835 GO:0005886 cellular_component plasma membrane
ENSSSCP00000030835 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSSCP00000030835 GO:0003707 molecular_function steroid hormone receptor activity
ENSSSCP00000030835 GO:0005496 molecular_function steroid binding
ENSSSCP00000030835 GO:0008270 molecular_function zinc ion binding
ENSSSCP00000030835 GO:0030284 molecular_function estrogen receptor activity
ENSSSCP00000030835 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
39432 Saimiri boliviensis 101034130 9365 Erinaceus europaeus ENSEEUG00000000828
9785 Loxodonta africana ENSLAFG00000015250 30608 Microcebus murinus ENSMICG00000007592
9258 Ornithorhynchus anatinus ENSOANG00000015561