Basic Information
Gene ID ENSMEUG00000003867
Gene Name ENSMEUG00000003867
Full Name ENSMEUG00000003867
Organism Macropus eugenii [9315]

Cross Reference
UniProt NULL UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSMEUP00000003534 Pfam PF00989 IPR013767 95 157 1.90e-05 PAS fold
ENSMEUP00000003534 Pfam PF11413 IPR021537 551 576 1.40e-12 Hypoxia-inducible factor, alpha subunit
ENSMEUP00000003534 PRINTS PR01080 IPR001321 202 225 5.20e-18 Hypoxia-inducible factor-1 alpha
ENSMEUP00000003534 PRINTS PR01080 IPR001321 361 379 5.20e-18 Hypoxia-inducible factor-1 alpha
ENSMEUP00000003534 ProSiteProfiles PS50112 IPR000014 248 299 0.00e-00 PAS domain
ENSMEUP00000003534 ProSiteProfiles PS50112 IPR000014 81 149 0.00e-00 PAS domain
ENSMEUP00000003534 ProSiteProfiles PS50888 IPR011598 18 71 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000003534 SMART SM00091 IPR000014 231 297 3.70e-10 PAS domain
ENSMEUP00000003534 SMART SM00091 IPR000014 88 154 1.40e-10 PAS domain
ENSMEUP00000003534 SMART SM00353 IPR011598 24 79 1.10e-11 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000003534 SUPERFAMILY SSF47459 IPR011598 16 72 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSMEUP00000003534 SUPERFAMILY SSF55785 IPR000014 243 294 0.00e-00 PAS domain
ENSMEUP00000003534 SUPERFAMILY SSF55785 IPR000014 97 200 0.00e-00 PAS domain
ENSMEUP00000003534 TIGRFAM TIGR00229 IPR000014 96 154 1.30e-06 PAS domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSMEUP00000003534 PF11413 7.8e-13 HIF-1 Hypoxia-inducible factor-1
ENSMEUP00000003534 PF00989 4.9e-12 PAS PAS fold
ENSMEUP00000003534 PF14598 1.4e-10 PAS_11 PAS domain
ENSMEUP00000003534 PF08447 3.7e-10 PAS_3 PAS fold
ENSMEUP00000003534 PF08448 3.7e-07 PAS_4 PAS fold
ENSMEUP00000003534 PF13426 6.9e-06 PAS_9 PAS domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSMEUP00000003534 GO:0001666 biological_process response to hypoxia
ENSMEUP00000003534 GO:0006351 biological_process transcription, DNA-templated
ENSMEUP00000003534 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSMEUP00000003534 GO:0007165 biological_process signal transduction
ENSMEUP00000003534 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSMEUP00000003534 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSMEUP00000003534 GO:0071456 biological_process cellular response to hypoxia
ENSMEUP00000003534 GO:0005634 cellular_component nucleus
ENSMEUP00000003534 GO:0005737 cellular_component cytoplasm
ENSMEUP00000003534 GO:0003677 molecular_function DNA binding
ENSMEUP00000003534 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSMEUP00000003534 GO:0004871 molecular_function signal transducer activity
ENSMEUP00000003534 GO:0035035 molecular_function histone acetyltransferase binding
ENSMEUP00000003534 GO:0046983 molecular_function protein dimerization activity

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9483 Callithrix jacchus 100411678 9597 Pan paniscus 100993223
9555 Papio anubis 100999094 39432 Saimiri boliviensis 101044689
9685 Felis catus 101083686 28377 Anolis carolinensis ENSACAG00000016205
9796 Equus caballus ENSECAG00000015597 9031 Gallus gallus ENSGALG00000011870
9785 Loxodonta africana ENSLAFG00000013410 9669 Mustela putorius furo 101692645
13735 Pelodiscus sinensis 102457736 9615 Canis familiaris 480348
9598 Pan troglodytes 746195 9646 Ailuropoda melanoleuca ENSAMEG00000003105
9358 Choloepus hoffmanni ENSCHOG00000008208 10141 Cavia porcellus ENSCPOG00000005317
10020 Dipodomys ordii ENSDORG00000004304 9595 Gorilla gorilla ENSGGOG00000003957
59463 Myotis lucifugus ENSMLUG00000015244 9601 Pongo abelii ENSPPYG00000005881
10116 Rattus norvegicus ENSRNOG00000008292 9823 Sus scrofa ENSSSCG00000005096
9103 Meleagris gallopavo ENSMGAG00000013552 13616 Monodelphis domestica ENSMODG00000008760
9258 Ornithorhynchus anatinus ENSOANG00000009092 9986 Oryctolagus cuniculus ENSOCUG00000017741
30611 Otolemur garnettii ENSOGAG00000016112 9978 Ochotona princeps ENSOPRG00000007753
42254 Sorex araneus ENSSARG00000011198 43179 Ictidomys tridecemlineatus ENSSTOG00000004833
59729 Taeniopygia guttata ENSTGUG00000012978 9739 Tursiops truncatus ENSTTRG00000012558
30538 Vicugna pacos ENSVPAG00000002395