Basic Information
Gene ID ENSRNOG00000014096 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Nr3c1
Full Name Glucocorticoid receptor
Organism Rattus norvegicus [10116]

Cross Reference
UniProt E9PT44 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000044335 Gene3D G3DSA:1.10.565.10 IPR008946 139 367 1.80e-66 Nuclear hormone receptor, ligand-binding
ENSRNOP00000044335 Gene3D G3DSA:3.30.50.10 IPR013088 23 102 1.00e-28 Zinc finger, NHR/GATA-type
ENSRNOP00000044335 Pfam PF00104 IPR000536 150 339 6.70e-31 Nuclear hormone receptor, ligand-binding, core
ENSRNOP00000044335 Pfam PF00105 IPR001628 25 92 1.60e-28 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 PRINTS PR00047 IPR001628 26 42 6.40e-15 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 PRINTS PR00047 IPR001628 42 57 6.40e-15 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 PRINTS PR00047 IPR001628 75 83 6.40e-15 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 PRINTS PR00047 IPR001628 83 91 6.40e-15 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 PRINTS PR00398 IPR001723 170 191 6.30e-14 Steroid hormone receptor
ENSRNOP00000044335 PRINTS PR00398 IPR001723 191 207 6.30e-14 Steroid hormone receptor
ENSRNOP00000044335 PRINTS PR00398 IPR001723 260 275 6.30e-14 Steroid hormone receptor
ENSRNOP00000044335 PRINTS PR00398 IPR001723 87 97 6.30e-14 Steroid hormone receptor
ENSRNOP00000044335 ProSitePatterns PS00031 IPR001628 26 52 - Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 ProSiteProfiles PS51030 IPR001628 23 98 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 SMART SM00399 IPR001628 23 94 2.50e-38 Zinc finger, nuclear hormone receptor-type
ENSRNOP00000044335 SMART SM00430 IPR000536 169 333 5.30e-35 Nuclear hormone receptor, ligand-binding, core
ENSRNOP00000044335 SUPERFAMILY SSF48508 IPR008946 76 361 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000044335 PF00104 5e-31 Hormone_recep Ligand-binding domain of nuclear hormone receptor
ENSRNOP00000044335 PF00105 9.2e-29 zf-C4 Zinc finger, C4 type (two domains)

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000044335 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000044335 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSRNOP00000044335 GO:0016568 biological_process chromatin modification
ENSRNOP00000044335 GO:0042921 biological_process glucocorticoid receptor signaling pathway
ENSRNOP00000044335 GO:0043401 biological_process steroid hormone mediated signaling pathway
ENSRNOP00000044335 GO:0043402 biological_process glucocorticoid mediated signaling pathway
ENSRNOP00000044335 GO:0005634 cellular_component nucleus
ENSRNOP00000044335 GO:0005737 cellular_component cytoplasm
ENSRNOP00000044335 GO:0005739 cellular_component mitochondrion
ENSRNOP00000044335 GO:0003677 molecular_function DNA binding
ENSRNOP00000044335 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSRNOP00000044335 GO:0003707 molecular_function steroid hormone receptor activity
ENSRNOP00000044335 GO:0004883 molecular_function glucocorticoid receptor activity
ENSRNOP00000044335 GO:0005496 molecular_function steroid binding
ENSRNOP00000044335 GO:0008270 molecular_function zinc ion binding
ENSRNOP00000044335 GO:0008289 molecular_function lipid binding
ENSRNOP00000044335 GO:0043565 molecular_function sequence-specific DNA binding
ENSRNOP00000044335 GO:0046872 molecular_function metal ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
59729 Taeniopygia guttata 100008583 9601 Pongo abelii 100189725
9483 Callithrix jacchus 100394916 8128 Oreochromis niloticus 100534398
9785 Loxodonta africana 100664515 9597 Pan paniscus 100970978
39432 Saimiri boliviensis 101043581 9669 Mustela putorius furo 101688907
43179 Ictidomys tridecemlineatus 101954529 59463 Myotis lucifugus 102429264
13735 Pelodiscus sinensis 102454070 28377 Anolis carolinensis ENSACAG00000013594
9646 Ailuropoda melanoleuca ENSAMEG00000010159 10141 Cavia porcellus ENSCPOG00000020113
9361 Dasypus novemcinctus ENSDNOG00000010685 10020 Dipodomys ordii ENSDORG00000010001
9685 Felis catus ENSFCAG00000011489 69293 Gasterosteus aculeatus ENSGACG00000018209
9031 Gallus gallus ENSGALG00000007394 9595 Gorilla gorilla ENSGGOG00000004334
8049 Gadus morhua ENSGMOG00000005668 9315 Macropus eugenii ENSMEUG00000009869
9544 Macaca mulatta ENSMMUG00000000421 9258 Ornithorhynchus anatinus ENSOANG00000005745
9986 Oryctolagus cuniculus ENSOCUG00000011676 30611 Otolemur garnettii ENSOGAG00000003356
8090 Oryzias latipes ENSORLG00000006022 9598 Pan troglodytes ENSPTRG00000017363
132908 Pteropus vampyrus ENSPVAG00000014255 9796 Equus caballus 100061217
61853 Nomascus leucogenys 100605325 10029 Cricetulus griseus 100763961
31033 Takifugu rubripes 101062852 7897 Latimeria chalumnae 102354325
10090 Mus musculus 14815 9606 Homo sapiens 2908
9823 Sus scrofa 396740 9615 Canis familiaris 478047
9358 Choloepus hoffmanni ENSCHOG00000013777 9365 Erinaceus europaeus ENSEEUG00000008977
9103 Meleagris gallopavo ENSMGAG00000009322 7757 Petromyzon marinus ENSPMAG00000005858
37347 Tupaia belangeri ENSTBEG00000016278 8364 Xenopus tropicalis ENSXETG00000001879
42254 Sorex araneus ENSSARG00000000617 9305 Sarcophilus harrisii ENSSHAG00000001727
99883 Tetraodon nigroviridis ENSTNIG00000008946 9478 Tarsius syrichta ENSTSYG00000013696
9739 Tursiops truncatus ENSTTRG00000003260 8083 Xiphophorus maculatus ENSXMAG00000009167