Basic Information
Gene ID ENSRNOG00000049232 ; Check Expression Profles ; Check TFs & Targets Binding
Gene Name Tcf7l2
Full Name Protein Tcf7l2
Organism Rattus norvegicus [10116]

Cross Reference
UniProt D4A8X6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSRNOP00000019681 Gene3D G3DSA:1.10.30.10 IPR009071 158 240 5.00e-29 High mobility group box domain
ENSRNOP00000019681 PANTHER PTHR10373 IPR024940 1 414 0.00e-00 Transcription factor TCF/LEF
ENSRNOP00000019681 PANTHER PTHR10373:SF26 IPR028773 1 414 0.00e-00 Transcription factor 7-like 2
ENSRNOP00000019681 Pfam PF00505 IPR009071 160 227 6.40e-22 High mobility group box domain
ENSRNOP00000019681 Pfam PF08347 IPR013558 1 75 2.90e-34 CTNNB1 binding, N-teminal
ENSRNOP00000019681 ProSiteProfiles PS50118 IPR009071 160 228 0.00e-00 High mobility group box domain
ENSRNOP00000019681 SMART SM00398 IPR009071 159 229 3.90e-25 High mobility group box domain
ENSRNOP00000019681 SUPERFAMILY SSF47095 IPR009071 159 240 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSRNOP00000019681 PF08347 2.9e-34 CTNNB1_binding N-terminal CTNNB1 binding
ENSRNOP00000019681 PF00505 3.7e-22 HMG_box HMG (high mobility group) box
ENSRNOP00000019681 PF09011 6.6e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSRNOP00000019681 GO:0006351 biological_process transcription, DNA-templated
ENSRNOP00000019681 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSRNOP00000019681 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSRNOP00000019681 GO:0007275 biological_process multicellular organismal development
ENSRNOP00000019681 GO:0016055 biological_process Wnt signaling pathway
ENSRNOP00000019681 GO:0060070 biological_process canonical Wnt signaling pathway
ENSRNOP00000019681 GO:0005634 cellular_component nucleus
ENSRNOP00000019681 GO:0003677 molecular_function DNA binding
ENSRNOP00000019681 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSRNOP00000019681 GO:0008013 molecular_function beta-catenin binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100120687 400682 Amphimedon queenslandica 100641322
9597 Pan paniscus 100978424 9555 Papio anubis 101026705
6239 Caenorhabditis elegans 171849 10090 Mus musculus 21416
7668 Strongylocentrotus purpuratus 373203 7227 Drosophila melanogaster 43769
7070 Tribolium castaneum 641465 9606 Homo sapiens 6934
28377 Anolis carolinensis ENSACAG00000010433 9646 Ailuropoda melanoleuca ENSAMEG00000015382
9913 Bos taurus ENSBTAG00000021574 7719 Ciona intestinalis ENSCING00000002003
9483 Callithrix jacchus ENSCJAG00000018987 7955 Danio rerio ENSDARG00000004415
9361 Dasypus novemcinctus ENSDNOG00000012035 9796 Equus caballus ENSECAG00000024121
9371 Echinops telfairi ENSETEG00000018612 9685 Felis catus ENSFCAG00000018774
69293 Gasterosteus aculeatus ENSGACG00000011184 9031 Gallus gallus ENSGALG00000026476
9785 Loxodonta africana ENSLAFG00000018192 9315 Macropus eugenii ENSMEUG00000011191
30608 Microcebus murinus ENSMICG00000007510 9544 Macaca mulatta ENSMMUG00000022799
13616 Monodelphis domestica ENSMODG00000010133 9258 Ornithorhynchus anatinus ENSOANG00000001579
8128 Oreochromis niloticus ENSONIG00000016240 9978 Ochotona princeps ENSOPRG00000005139
8090 Oryzias latipes ENSORLG00000008387 9601 Pongo abelii ENSPPYG00000002661
9598 Pan troglodytes ENSPTRG00000002949 132908 Pteropus vampyrus ENSPVAG00000016688
7029 Acyrthosiphon pisum 100161896 6087 Hydra magnipapillata 100199257
10224 Saccoglossus kowalevskii 100303556 34638 Metaseiulus occidentalis 100905988
39432 Saimiri boliviensis 101037011 13735 Pelodiscus sinensis 102459521
9615 Canis familiaris ENSCAFG00000011005 10141 Cavia porcellus ENSCPOG00000002152
51511 Ciona savignyi ENSCSAVG00000007833 10020 Dipodomys ordii ENSDORG00000011398
9365 Erinaceus europaeus ENSEEUG00000007595 9595 Gorilla gorilla ENSGGOG00000008549
8049 Gadus morhua ENSGMOG00000007406 7897 Latimeria chalumnae ENSLACG00000015707
59463 Myotis lucifugus ENSMLUG00000008783 9669 Mustela putorius furo ENSMPUG00000002032
61853 Nomascus leucogenys ENSNLEG00000015863 9986 Oryctolagus cuniculus ENSOCUG00000008142
30611 Otolemur garnettii ENSOGAG00000014475 7757 Petromyzon marinus ENSPMAG00000004519
9305 Sarcophilus harrisii ENSSHAG00000017344 43179 Ictidomys tridecemlineatus ENSSTOG00000006847
9823 Sus scrofa ENSSSCG00000010638 37347 Tupaia belangeri ENSTBEG00000002995
59729 Taeniopygia guttata ENSTGUG00000010805 99883 Tetraodon nigroviridis ENSTNIG00000010305
31033 Takifugu rubripes ENSTRUG00000012549 9478 Tarsius syrichta ENSTSYG00000012796
9739 Tursiops truncatus ENSTTRG00000002360 30538 Vicugna pacos ENSVPAG00000008158
8364 Xenopus tropicalis ENSXETG00000018735 8083 Xiphophorus maculatus ENSXMAG00000014710

Paralogs
161452