Basic Information
Gene ID ENSSHAG00000017344
Gene Name TCF7L2
Full Name Uncharacterized protein
Organism Sarcophilus harrisii [9305]

Cross Reference
UniProt G3WYE8 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSHAP00000020453 Gene3D G3DSA:1.10.30.10 IPR009071 325 407 6.10e-29 High mobility group box domain
ENSSHAP00000020453 Gene3D G3DSA:4.10.900.10 IPR027397 1 60 5.50e-32 Catenin binding domain
ENSSHAP00000020453 PANTHER PTHR10373 IPR024940 1 460 0.00e-00 Transcription factor TCF/LEF
ENSSHAP00000020453 PANTHER PTHR10373:SF26 IPR028773 1 460 0.00e-00 Transcription factor 7-like 2
ENSSHAP00000020453 Pfam PF00505 IPR009071 327 394 7.80e-22 High mobility group box domain
ENSSHAP00000020453 Pfam PF08347 IPR013558 1 236 8.80e-93 CTNNB1 binding, N-teminal
ENSSHAP00000020453 ProSiteProfiles PS50118 IPR009071 327 395 0.00e-00 High mobility group box domain
ENSSHAP00000020453 SMART SM00398 IPR009071 326 396 3.90e-25 High mobility group box domain
ENSSHAP00000020453 SUPERFAMILY SSF47095 IPR009071 326 407 0.00e-00 High mobility group box domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSHAP00000020453 PF08347 0 CTNNB1_binding N-terminal CTNNB1 binding
ENSSHAP00000020453 PF00505 3.4e-22 HMG_box HMG (high mobility group) box
ENSSHAP00000020453 PF09011 5.7e-08 HMG_box_2 HMG-box domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSHAP00000020453 GO:0006351 biological_process transcription, DNA-templated
ENSSHAP00000020453 GO:0006355 biological_process regulation of transcription, DNA-templated
ENSSHAP00000020453 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSSHAP00000020453 GO:0007275 biological_process multicellular organismal development
ENSSHAP00000020453 GO:0016055 biological_process Wnt signaling pathway
ENSSHAP00000020453 GO:0060070 biological_process canonical Wnt signaling pathway
ENSSHAP00000020453 GO:0005634 cellular_component nucleus
ENSSHAP00000020453 GO:0003677 molecular_function DNA binding
ENSSHAP00000020453 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSSHAP00000020453 GO:0008013 molecular_function beta-catenin binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
7425 Nasonia vitripennis 100120687 400682 Amphimedon queenslandica 100641322
9597 Pan paniscus 100978424 9555 Papio anubis 101026705
6239 Caenorhabditis elegans 171849 10090 Mus musculus 21416
7668 Strongylocentrotus purpuratus 373203 7227 Drosophila melanogaster 43769
7070 Tribolium castaneum 641465 9606 Homo sapiens 6934
28377 Anolis carolinensis ENSACAG00000010433 9646 Ailuropoda melanoleuca ENSAMEG00000015382
9913 Bos taurus ENSBTAG00000021574 7719 Ciona intestinalis ENSCING00000002003
9483 Callithrix jacchus ENSCJAG00000018987 51511 Ciona savignyi ENSCSAVG00000007833
7955 Danio rerio ENSDARG00000004415 9361 Dasypus novemcinctus ENSDNOG00000012035
9796 Equus caballus ENSECAG00000024121 9365 Erinaceus europaeus ENSEEUG00000007595
9685 Felis catus ENSFCAG00000018774 9785 Loxodonta africana ENSLAFG00000018192
30608 Microcebus murinus ENSMICG00000007510 9544 Macaca mulatta ENSMMUG00000022799
13616 Monodelphis domestica ENSMODG00000010133 9258 Ornithorhynchus anatinus ENSOANG00000001579
8128 Oreochromis niloticus ENSONIG00000016240 9978 Ochotona princeps ENSOPRG00000005139
9601 Pongo abelii ENSPPYG00000002661 9598 Pan troglodytes ENSPTRG00000002949
132908 Pteropus vampyrus ENSPVAG00000016688 10116 Rattus norvegicus ENSRNOG00000049232
7029 Acyrthosiphon pisum 100161896 6087 Hydra magnipapillata 100199257
10224 Saccoglossus kowalevskii 100303556 34638 Metaseiulus occidentalis 100905988
39432 Saimiri boliviensis 101037011 13735 Pelodiscus sinensis 102459521
9615 Canis familiaris ENSCAFG00000011005 10141 Cavia porcellus ENSCPOG00000002152
10020 Dipodomys ordii ENSDORG00000011398 7897 Latimeria chalumnae ENSLACG00000015707
59463 Myotis lucifugus ENSMLUG00000008783 9669 Mustela putorius furo ENSMPUG00000002032
61853 Nomascus leucogenys ENSNLEG00000015863 9986 Oryctolagus cuniculus ENSOCUG00000008142
30611 Otolemur garnettii ENSOGAG00000014475 7757 Petromyzon marinus ENSPMAG00000004519
9823 Sus scrofa ENSSSCG00000010638 43179 Ictidomys tridecemlineatus ENSSTOG00000006847
37347 Tupaia belangeri ENSTBEG00000002995 59729 Taeniopygia guttata ENSTGUG00000010805
31033 Takifugu rubripes ENSTRUG00000012549 9478 Tarsius syrichta ENSTSYG00000012796
9739 Tursiops truncatus ENSTTRG00000002360 8364 Xenopus tropicalis ENSXETG00000018735
8083 Xiphophorus maculatus ENSXMAG00000014710

Paralogs
ENSSHAG00000006659