Basic Information
Gene ID ENSSSCG00000011890
Gene Name PXR; NR1I2
Full Name Pregnane X receptor
Organism Sus scrofa [9823]

Cross Reference
UniProt A5J0K7 UniGene Ssc.84334
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSSSCP00000012667 Gene3D G3DSA:1.10.565.10 IPR008946 178 418 1.40e-64 Nuclear hormone receptor, ligand-binding
ENSSSCP00000012667 Gene3D G3DSA:1.10.565.10 IPR008946 82 112 1.40e-64 Nuclear hormone receptor, ligand-binding
ENSSSCP00000012667 Gene3D G3DSA:3.30.50.10 IPR013088 27 81 1.50e-23 Zinc finger, NHR/GATA-type
ENSSSCP00000012667 Pfam PF00104 IPR000536 224 397 2.80e-22 Nuclear hormone receptor, ligand-binding, core
ENSSSCP00000012667 Pfam PF00105 IPR001628 26 95 2.90e-27 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 PRINTS PR00047 IPR001628 27 43 5.10e-18 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 PRINTS PR00047 IPR001628 43 58 5.10e-18 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 PRINTS PR00047 IPR001628 77 85 5.10e-18 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 PRINTS PR00047 IPR001628 85 93 5.10e-18 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 PRINTS PR00398 IPR001723 233 254 3.30e-21 Steroid hormone receptor
ENSSSCP00000012667 PRINTS PR00398 IPR001723 254 270 3.30e-21 Steroid hormone receptor
ENSSSCP00000012667 PRINTS PR00398 IPR001723 320 335 3.30e-21 Steroid hormone receptor
ENSSSCP00000012667 PRINTS PR00398 IPR001723 379 396 3.30e-21 Steroid hormone receptor
ENSSSCP00000012667 PRINTS PR00398 IPR001723 89 99 3.30e-21 Steroid hormone receptor
ENSSSCP00000012667 ProSitePatterns PS00031 IPR001628 27 53 - Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 ProSiteProfiles PS51030 IPR001628 24 100 0.00e-00 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 SMART SM00399 IPR001628 24 96 8.90e-38 Zinc finger, nuclear hormone receptor-type
ENSSSCP00000012667 SMART SM00430 IPR000536 232 391 4.90e-37 Nuclear hormone receptor, ligand-binding, core
ENSSSCP00000012667 SUPERFAMILY SSF48508 IPR008946 129 417 0.00e-00 Nuclear hormone receptor, ligand-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSSSCP00000012667 PF00105 1.5e-27 zf-C4 Zinc finger, C4 type (two domains)
ENSSSCP00000012667 PF00104 1.2e-22 Hormone_recep Ligand-binding domain of nuclear hormone receptor

Gene Ontology Annotation
Protein Entry Name Space Description
ENSSSCP00000012667 GO:0005634 cellular_component nucleus
ENSSSCP00000012667 GO:0003707 molecular_function steroid hormone receptor activity
ENSSSCP00000012667 GO:0008270 molecular_function zinc ion binding
ENSSSCP00000012667 GO:0043565 molecular_function sequence-specific DNA binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9986 Oryctolagus cuniculus 100008739 10029 Cricetulus griseus 100768934
9555 Papio anubis 101024860 9595 Gorilla gorilla 101124311
9598 Pan troglodytes 745458 10020 Dipodomys ordii ENSDORG00000003966
9796 Equus caballus ENSECAG00000008728 9371 Echinops telfairi ENSETEG00000018117
59463 Myotis lucifugus ENSMLUG00000002877 9669 Mustela putorius furo ENSMPUG00000008376
61853 Nomascus leucogenys ENSNLEG00000005060 9978 Ochotona princeps ENSOPRG00000010448
9601 Pongo abelii ENSPPYG00000013508 132908 Pteropus vampyrus ENSPVAG00000000884
42254 Sorex araneus ENSSARG00000002684 8128 Oreochromis niloticus 100534472
9597 Pan paniscus 100971952 39432 Saimiri boliviensis 101051844
10090 Mus musculus 18171 9913 Bos taurus 493713
9606 Homo sapiens 9970 9646 Ailuropoda melanoleuca ENSAMEG00000007006
9615 Canis familiaris ENSCAFG00000011094 9358 Choloepus hoffmanni ENSCHOG00000008181
9483 Callithrix jacchus ENSCJAG00000008854 10141 Cavia porcellus ENSCPOG00000020161
9365 Erinaceus europaeus ENSEEUG00000004541 9685 Felis catus ENSFCAG00000006092
7897 Latimeria chalumnae ENSLACG00000010334 9785 Loxodonta africana ENSLAFG00000007829
9315 Macropus eugenii ENSMEUG00000000113 30608 Microcebus murinus ENSMICG00000008054
9544 Macaca mulatta ENSMMUG00000001976 13616 Monodelphis domestica ENSMODG00000018212
30611 Otolemur garnettii ENSOGAG00000006017 8090 Oryzias latipes ENSORLG00000017953
13735 Pelodiscus sinensis ENSPSIG00000004437 9305 Sarcophilus harrisii ENSSHAG00000004437
99883 Tetraodon nigroviridis ENSTNIG00000013932 31033 Takifugu rubripes ENSTRUG00000003245
9478 Tarsius syrichta ENSTSYG00000010757 30538 Vicugna pacos ENSVPAG00000009309
8083 Xiphophorus maculatus ENSXMAG00000003990 43179 Ictidomys tridecemlineatus ENSSTOG00000014988
9739 Tursiops truncatus ENSTTRG00000016650 8364 Xenopus tropicalis ENSXETG00000018029