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    At Work: Forbes: Illumina adds IBM Watson to DNA test for cancer patients
    Submitted by J.W. Bizzaro; posted on Wednesday, January 11, 2017

    Submitter

    EXCERPT

    Illumina and IBM announced that they would be bundling IBM's Watson Genomics product with Illumina's TruSight Tumor 170, a tool used to help match very sick cancer patients with drugs that might help them.

    The move is the latest effort by DNA sequencing companies to try to get doctors outside major cancer centers like Memorial Sloan-Kettering Cancer Center in New York or M.D. Anderson Cancer Center in Houston to try to scan patients' DNA. The idea is that the DNA test results can be used to help patients who don't have any options find medicines – either approved or experimental – that might help them. So far, this is considered standard practice for late-stage non-small cell lung cancer, but not for cancers in general.
    Source: www.forbes.com/site[...]2163e
    Open Access: Bio-IT World: Interference: A CRISPR patent dispute roadmap
    Submitted by J.W. Bizzaro; posted on Tuesday, January 10, 2017

    Submitter

    EXCERPT

    Emmanuelle Charpentier and Jennifer Doudna have become world renowned for their discoveries and development involving CRISPR/Cas9, a gene-editing technology that has been called "one of the most important genetic inventions of our time".

    In 2014, the duo received the 2015 Breakthrough Prize in Life Sciences. The following year, Charpentier and Doudna were also co-awarded the €50,000 Princess of Asturias Award of Technical and Scientific Research – commonly referred to as the "Spanish Nobel Prize". The pair also garnered a nomination for the actual Nobel Prize in Chemistry.

    Meanwhile, on April 15, 2014, another genetic researcher, Feng Zhang, was awarded something potentially much more valuable than the Nobel Prize: a patent by the United States Patent and Trademark Office (USPTO) for the very same thing for which Charpentier and Doudna have received so many accolades: using CRISPR/Cas9 to edit genes.
    Source: www.bio-itworld.com/2017[...].aspx

    Submitter

    EXCERPT

    HS patients will be assessed by robots under a controversial 111 scheme to use "artificial intelligence" to ease pressures on Accident & Emergency units.

    More than one million people will be given access to a free app which means they can consult with a "chatbot" instead of a human being.

    Hospitals across the country are struggling to cope with unprecedented demand, which has left thousands of casualty patients waiting on trolleys.
    Source: www.telegraph.co.uk/tech[...]line/
    Education: Workshop on Computer Aided Drug Designing
    Submitted by Bioinformatics centre - MVC; posted on Thursday, January 05, 2017

    February 13-17, 2017
    Madras Veterinary College, Chennai, India
    www.btismvc.ac.in

    The Bioinformatics Centre of Madras Veterinary College is conducting a five-day Workshop on Computer Aided Drug Designing. Twenty five participants will be selected on a first come, first served basis.

    FOR MORE INFORMATION

    Contact:
    Dr. P. Kumarasamy, Professor and Head, BTIS, MVC, Chennai
    Phone-Direct: 044-25360106/25360114
    Phone-Board: 044-25304000 ext. 2064
    Tele Fax: 044-25360114
    Mobile: 09444233349
    Mail: hodbitmvc[at]tanuvas.org.in, kumarasamy.p[at]tanuvas.ac.in, tnvasuniv.btisnet[at]nic.in

    Submitter

    EXCERPT

    Based on the study of cell signaling networks, the cell signals that drugs alter when they reach their target molecule, an exhaustive in silico analysis of the pairing of 64 therapeutic agents used to treat breast cancer (half already in use and the other half in clinical testing phase) has allowed researchers at the Institute for Research in Biomedicine (IRB Barcelona) to identify 10 new and previously untested combinations that hold potential for the treatment of breast cancer.
    Source: www.sciencedaily.com/rele[...]8.htm

    Submitter

    EXCERPT

    The new study is very small, but it aligns with other recent work comparing tissue and liquid-biopsy sequencing results. A paper from Northwestern researchers in August looking at these same two tests, for example, found that more than half of the mutations identified by one test did not show up in the other. Another study looking at a few especially important mutations (for many kinds of cancers) found the tests agreed 70.3 percent or 88.1 percent or 93.1 percent of the time, depending on the mutation.
    Source: www.theatlantic.com/heal[...]0656/

    We are happy to announce Pathview Web server. Pathview maps, integrates and renders a wide variety of biological data on relevant pathway graphs.

    Pathview web server extends the core functions of Pathview with:
    • A simple intuitive graphical user interface
    • Fast and programmatic access through RESTful API
    • Complete pathway analysis workflow supporting multiple omics data and integrated analysis
    • Interactive and hyperlinked results graphs for better data interpretation
    • Most complete and up-to-date pathway data via regular database synchronization
    • Open access to all analyses and resources
    • Analysis history and data sharing via free registered user accounts
    • Complete online help and documentation
    • Multiple quick-start example analyses
    It was updated substantially in the last few months.

    AVAILABILITY

    It is freely/openly accessible online at pathview.uncc.edu.
    Books: The Biostar Handbook, a bioinformatics e-book for beginners
    Submitted by Istvan Albert; posted on Thursday, December 08, 2016

    After almost two years of work, the Biostar Handbook has been published. It is a passionately and lovingly crafted e-book that makes a challenging subject accessible and, dare we say, fun.

    The Biostar Handbook introduces readers to bioinformatics, the scientific discipline at the intersection of biology, computer science, and statistical data analytics dedicated to the digital processing of genomic information.

    The e-book delivers simple, concise, and relevant information for those looking to understand the field of bioinformatics as a data science. It is a comprehensive, practical handbook that covers major application areas of bioinformatics from short read alignment to RNA-Seq data analysis.

    Get the Biostar Handbook at: biostar.myshopify.com

    See the current table of contents and read free excerpts from the book at: read.biostarhandbook.com
    Education: Canadian Bioinformatics Workshops 2017 Series
    Submitted by Ann Meyer; posted on Tuesday, December 06, 2016

    The CBW is pleased to be offering the following advanced training opportunities in 2017:
    • High-Throughput Biology – From Sequence to Networks: Cold Spring Harbor, NY, March 20-26, 2017
    • Infectious Disease Genomic Epidemiolgy: Vancouver, May 1-3, 2017 (NEW)
    • Bioinformatics of Genomic Medicine: Toronto, May 10-11, 2017 (NEW)
    • Informatics on High-throughput Sequencing Data: Toronto, May 25-26, 2017
    • Bioinformatics for Cancer Genomics: Toronto, May 29 – June 2, 2017
    • Informatics and Statistics for Metabolomics: Toronto, June 6-7, 2017
    • Introduction to R: Toronto, June 12, 2017
    • Exploratory Analysis of Biological Data using R: Toronto, June 13-14, 2017
    • Epigenomic Data Analysis: Montreal, June 15-16, 2017
    • Microbiome Summer School: Quebec City, June 19-22, 2017 (NEW)
    • Pathway and Network Analysis of -omics Data: Toronto, June 26-28, 2017
    • Cloud Computing in Bioinformatics with Big Data: Toronto, July 5-6, 2017
    • Informatics for RNA-seq Analysis: Toronto, July 10-12, 2017 (1 day longer)
    New for 2017:
    • Workshops will be held in Vancouver, Montreal, Quebec City, Cold Spring Harbor, and Toronto
    • Travel and registration awards to eligible trainees
    • New workshops in epidemiology, genomic medicine, and the microbiome
    A link to our new full program poster can be found here: goo.gl/a3zi4d (PDF). For more information, visit bioinformatics.ca.

    Applications for our 2017 workshops will be opening soon!

    Submitter

    EXCERPT

    The Breakthrough Prize gave away $25 million dollars to more than a thousand scientists on Sunday.

    The Prize is the brainchild of Russian tech billionaire Yuri Milner. Milner, who also funds research investigating Tabby's Star (of "alien megastructure" fame), brought tech all-stars including Sergey Brin, Mark Zuckerberg, and Anne Wojcicki on board for the prize, which seeks to add a bit of glamour and excitement to the world of scientific prizes. Morgan Freeman hosted this year's awards, televised live on National Geographic and soon to be rebroadcast on Fox.
    Source: www.popularmechanics.com/scie[...]2016/
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