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An article by Denise Grady:
"The scientists who altered a deadly flu virus to make it more contagious have agreed to suspend their research for 60 days to give other researchers around the world time to discuss the work and determine the best way to proceed.
"A letter explaining the decision ([link]) is being published in two scientific journals, Science and Nature, which also plan to publish reports on the research, but in a redacted form omitting details that would let other researchers copy the experiments. The letter is signed by the scientists who produced the new, more contagious form of the flu virus, as well as by other leading flu researchers."
FULL STORY:
[link]
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DATES: Next start date: March 2012
LOCALE: Online at The University of Manchester, UK
URL: [link]
This online course from The University of Manchester, UK, covers microarray data analysis in depth, and also introduces the areas where new work is needed for next generation sequence (RNA-seq) analysis.
Course details:
Week 1: Introduction and software setup
Weeks 2 and 3: Microarrays and experimental design
Weeks 4 and 5: Data capture and preliminary checks
Weeks 6 and 7: Data analysis
Weeks 8 and 9: Other methods for transcriptome analysis
Weeks 10 and 11: Independent research and work on the first assessment
Weeks 12 and 13: Gene Class Tests
Weeks 14 to 16: Independent research and work on the second assessment
This is just one of our Masters-level courses in Digital Biology. You will find information on all our courses, including fees and a link to the enquiry form, here: [link]
FOR MORE INFORMATION:
If you need further information, or would like to book a place on a course, please contact our office for Advanced Professional Education (ape[at]cs.man.ac.uk).
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"Proteins and their variants: structure and function prediction"
DATES: February 13-17, 2012
LOCALE: Bologna, Italy
URL: http://www.biocomp.unibo.it/~school2012/
As a result of large sequencing projects, data banks of protein sequences and structures are growing rapidly. The number of sequences is however orders of magnitude larger than the number of structures known at the atomic level, and this is so in spite of efforts in accelerating processes to determine the resolution of protein structure.
Tools have been developed in order to bridge the gap between sequence and protein 3D structure, based on the notion that information is to be retrieved from the data bases and that knowledge-based methods can help in approaching a solution of the protein folding problem. By this, several features can be predicted starting from a protein sequence, such as structural and functional motifs and domains, including the topological organization of a protein inside the membrane phase, and the formation of disulfide bonds in a folded protein structure.
Different computational methods, mainly based on machine learning, e.g. neural networks (NNs), hidden markov models (HMMs), support vector machines (SVMs), which are capable of computing the likelihood of a given feature starting from the protein sequence, can be used to endow protein sequences with structural features. The process of large scale proteome annotation (endowing sequences with functional and structural features) will be debated by focusing also on how to describe protein function with Gene Ontologies and predicting them from the protein sequence.
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"As I discussed in a recent post, quite a bit of scientific research these days is federally funded. If your funding comes from the National Institutes of Health (NIH), you are required to make your work publicly available by depositing it in PubMed Central, a database of full-text scientific articles. The reasoning is that the public should have access to the research that they are funding through the tax dollars, which I think seems reasonable enough.
"Not surprisingly, the publishers who print the articles in the journals don't agree, and they have lobbied for the introduction of a piece of legislation that would put an end to the NIH Public Access Policy and similar measures to ensure public access to federally funded works. The bill, called the Research Works Act, would prevent the government from requiring free dissemination of research articles that have been funded by federal dollars and also prohibit the government from developing open access repositories, like PubMed Central. According to its proponents, this legislation is necessary to protect publishers from having to give away their articles for free, which would discourage them from investing in the publication process. The Association of American Publishers' response is available here."
FULL ARTICLE:
[link]
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DATES: 15-17 February 2012
LOCALE: VITS Hotel, Balewadi, Pune, India
URL: [link]
Accelerating Biology 2012 (Computing to Decipher) is a 3-Day symposium on current trends in Bioinformatics. The sessions will comprise of invited talks from eminent academicians from esteemed national institutes. The talks will address the challenges in the areas of Next Generation Sequencing technologies, genome analysis, advanced molecular dynamics simulations and algorithm development, High Performance Computing (HPC) and cloud computing. The symposium is targeted at students and researchers from academic institutes, universities and Bioinformatics industries.
Registration ends: 15 January 2012
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DATES: 27-29 February 2012
LOCALE: Genome Campus, Hinxton, UK
URL: [link]
DAS is currently being used to share annotations on genomes, protein alignments, structural and interaction information. If you are interested in sharing biological information the DAS workshop below may be of interest to you.
Learn of and contribute to current developments in DAS such as: DAS in the cloud, DAS for Genotype Data, DAS searching, DAS for collaborative annotation projects, DAS alternative formats.
REGISTRATION:
Registration is open. If you are interested in attending, please find out more by going to [link] and register via the web link at the bottom of the page. This workshop will cater for novice to expert DAS users as each day is optional.
Please register early as places will be limited. Registration closes 10 February 2012 - 12:00.
If you are interested in giving a 15 minute talk on the second day please email Jonathan Warren using jonathan.warren[at]sanger.ac.uk
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DATES: 1-2 March 2012
LOCALE: Centro di Biotecnologie Molecolari, Via Nizza 52, Torino, Italy
URL (PDF): [link]
Next Generation Sequencing platforms changes the conventional view of transcript analysis. Massive Parallel Sequencing methods(MPS) can extend and improve the knowledge obtained by conventional microarray technology, both for mRNAs and short non-coding RNAs, e.g. miRNAs.
This hands-on course is organized by B&Gu (http://www.bioinformatica.unito.it/) with guest speakers from Illumina (http://www.illumina.com/), Singapore Immunology Network and Polytechnic of Torino. The course is suitable for biologists who are new to RNA-seq technology. Additionally, if you have analyzed gene expression data from microarrays and would now like to do projects using RNA-seq technology, then this workshop will enable you to gather information on the critical issue on RNA-seq from sample prep to data analysis.
The course is based on the use of Bioconductor (http://www.bioconductor.org) open-source software. However, R (http://www.r-project.org) coding skill is not required since all the analyses are done using oneChannelGUI ([link]), a graphical interface to Bioconductor tools, designed for life scientists who are not familiar with R language.
Knowledge of statistics is not necessary prior to attending the course.
FOR MORE INFORMATION:
Further course information, agenda and logistics can be found in the course booklet [link].
Organizer:
Prof. Raffaele A. Calogero
raffaele[dot]calogero[at]gmail[dot]com
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DATES: Feb. 23-25, 2012
LOCALE: Las Vegas, Nevada, USA
URL: http://www.iccabs.org/
IMPORTANT DATES:
Paper submission: Jan. 17, 2012 (Final Deadline)
Notification of acceptance: Jan. 31, 2012
Camera-ready version and author registration: Feb. 6, 2012
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DATES: May 11 & 13, 2012
LOCALE: Comwell Spa Resort, north of Copenhagen, Denmark
URL: http://www.networkbio.org/
REGISTRATION NOW OPEN!
The theme of this conference will be the use of novel experimental and computational approaches to study signalling networks, and how network models can be applied to the study and targeting of complex diseases such as cancer, diabetes and neurological disorders.
The conference venue will be the Comwell Spa Resort North of Copenhagen and a reception will take place at the world-renowned Louisiana Museum of Modern Art.
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DATES: Feb. 23-25, 2012
LOCALE: Las Vegas, Nevada, USA
URL: http://www.iccabs.org/
Advances in high-throughput technologies such as DNA sequencing and mass spectrometry are profoundly transforming life sciences, resulting in the collection of unprecedented amounts of biological and medical data. Using this data to advance our knowledge about fundamental biological processes and improve human health requires novel computational models and advanced analysis algorithms. IEEE ICCABS aims to bring together leading academic and industry researchers to discuss the latest advances in computational methods for bio and medical sciences.
Topics of interest include but are not limited to: biological modeling and simulation; biomedical image processing; biomedical data and literature mining; computational genetic epidemiology; computational metabolomics; computational proteomics; databases and ontologies; gene regulation; genome analysis; health informatics; high-performance bio-computing; immunoinformatics; molecular evolution; population genomics; sequence analysis; structural bioinformatics; systems biology; transcriptomics.
IMPORTANT DATES:
Abstract submission: Jan. 3, 2012 (extended)
Notification of acceptance: Jan. 25, 2012
Camera-ready version and author registration: Feb. 2, 2012
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![[?]](/images/ic/info.png)