
Basic Information | |||
| Gene ID | 100005148 | ||
| Gene Name | ar | ||
| Full Name | Androgen receptor | ||
| Organism | Danio rerio [7955] | ||
Cross Reference | |||
| UniProt | A4GT83 | UniGene | Dr.75914 |
| PDB | NULL | OMIM | NULL |
| KEGG | dre:100005148 | UCSC | NULL |
Protein Interactions | |
| DIP | NULL |
| IntAct | NULL |
| MINT | NULL |
| STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
| Protein | Program | Term | IPRS | Start | End | Score | Description |
| ENSDARP00000088795 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 628 | 855 | 6.70e-70 | Nuclear hormone receptor, ligand-binding |
| ENSDARP00000088795 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 508 | 581 | 4.10e-26 | Zinc finger, NHR/GATA-type |
| ENSDARP00000088795 | Pfam | PF00104 | IPR000536 | 647 | 824 | 4.00e-29 | Nuclear hormone receptor, ligand-binding, core |
| ENSDARP00000088795 | Pfam | PF00105 | IPR001628 | 511 | 578 | 3.00e-27 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | Pfam | PF02166 | IPR001103 | 157 | 206 | 7.20e-06 | Androgen receptor |
| ENSDARP00000088795 | PRINTS | PR00047 | IPR001628 | 512 | 528 | 2.30e-13 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | PRINTS | PR00047 | IPR001628 | 528 | 543 | 2.30e-13 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | PRINTS | PR00047 | IPR001628 | 561 | 569 | 2.30e-13 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | PRINTS | PR00047 | IPR001628 | 569 | 577 | 2.30e-13 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | PRINTS | PR00398 | IPR001723 | 573 | 583 | 3.10e-13 | Steroid hormone receptor |
| ENSDARP00000088795 | PRINTS | PR00398 | IPR001723 | 657 | 678 | 3.10e-13 | Steroid hormone receptor |
| ENSDARP00000088795 | PRINTS | PR00398 | IPR001723 | 678 | 694 | 3.10e-13 | Steroid hormone receptor |
| ENSDARP00000088795 | PRINTS | PR00398 | IPR001723 | 747 | 762 | 3.10e-13 | Steroid hormone receptor |
| ENSDARP00000088795 | ProSitePatterns | PS00031 | IPR001628 | 512 | 538 | - | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | ProSiteProfiles | PS51030 | IPR001628 | 509 | 584 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | SMART | SM00399 | IPR001628 | 509 | 580 | 6.20e-35 | Zinc finger, nuclear hormone receptor-type |
| ENSDARP00000088795 | SMART | SM00430 | IPR000536 | 656 | 818 | 1.60e-39 | Nuclear hormone receptor, ligand-binding, core |
| ENSDARP00000088795 | SUPERFAMILY | SSF48508 | IPR008946 | 623 | 867 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
| Protein | Pfam ID | E.value | Name | Description |
| ENSDARP00000088795 | PF00104 | 2.1e-29 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
| ENSDARP00000088795 | PF00105 | 1e-27 | zf-C4 | Zinc finger, C4 type (two domains) |
| ENSDARP00000088795 | PF02166 | 7.2e-06 | Androgen_recep | Androgen receptor |
Gene Ontology Annotation | |||
| Protein | Entry | Name Space | Description |
| ENSDARP00000088795 | GO:0006351 | biological_process | transcription, DNA-templated |
| ENSDARP00000088795 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
| ENSDARP00000088795 | GO:0008284 | biological_process | positive regulation of cell proliferation |
| ENSDARP00000088795 | GO:0030521 | biological_process | androgen receptor signaling pathway |
| ENSDARP00000088795 | GO:0030522 | biological_process | intracellular receptor signaling pathway |
| ENSDARP00000088795 | GO:0042327 | biological_process | positive regulation of phosphorylation |
| ENSDARP00000088795 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
| ENSDARP00000088795 | GO:0045720 | biological_process | negative regulation of integrin biosynthetic process |
| ENSDARP00000088795 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
| ENSDARP00000088795 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
| ENSDARP00000088795 | GO:0051092 | biological_process | positive regulation of NF-kappaB transcription factor activity |
| ENSDARP00000088795 | GO:0090003 | biological_process | regulation of establishment of protein localization to plasma membrane |
| ENSDARP00000088795 | GO:2001237 | biological_process | negative regulation of extrinsic apoptotic signaling pathway |
| ENSDARP00000088795 | GO:0000790 | cellular_component | nuclear chromatin |
| ENSDARP00000088795 | GO:0005634 | cellular_component | nucleus |
| ENSDARP00000088795 | GO:0005737 | cellular_component | cytoplasm |
| ENSDARP00000088795 | GO:0003677 | molecular_function | DNA binding |
| ENSDARP00000088795 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
| ENSDARP00000088795 | GO:0003707 | molecular_function | steroid hormone receptor activity |
| ENSDARP00000088795 | GO:0004879 | molecular_function | ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity |
| ENSDARP00000088795 | GO:0004882 | molecular_function | androgen receptor activity |
| ENSDARP00000088795 | GO:0005496 | molecular_function | steroid binding |
| ENSDARP00000088795 | GO:0008013 | molecular_function | beta-catenin binding |
| ENSDARP00000088795 | GO:0008270 | molecular_function | zinc ion binding |
| ENSDARP00000088795 | GO:0008289 | molecular_function | lipid binding |
| ENSDARP00000088795 | GO:0043565 | molecular_function | sequence-specific DNA binding |
| ENSDARP00000088795 | GO:0044212 | molecular_function | transcription regulatory region DNA binding |
| ENSDARP00000088795 | GO:0046872 | molecular_function | metal ion binding |
Orthologs | |||||
| TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
| 9601 | Pongo abelii | 100454831 | 9785 | Loxodonta africana | 100664515 |
| 10029 | Cricetulus griseus | 100765080 | 30611 | Otolemur garnettii | 100960541 |
| 9597 | Pan paniscus | 100976456 | 9555 | Papio anubis | 101020931 |
| 9669 | Mustela putorius furo | 101681169 | 43179 | Ictidomys tridecemlineatus | 101970574 |
| 8083 | Xiphophorus maculatus | 102229873 | 59463 | Myotis lucifugus | 102427580 |
| 10090 | Mus musculus | 11835 | 10116 | Rattus norvegicus | 24208 |
| 9913 | Bos taurus | 280675 | 9606 | Homo sapiens | 5241 |
| 28377 | Anolis carolinensis | ENSACAG00000013594 | 9615 | Canis familiaris | ENSCAFG00000016656 |
| 9358 | Choloepus hoffmanni | ENSCHOG00000007092 | 9483 | Callithrix jacchus | ENSCJAG00000003563 |
| 10141 | Cavia porcellus | ENSCPOG00000007636 | 9361 | Dasypus novemcinctus | ENSDNOG00000010685 |
| 10020 | Dipodomys ordii | ENSDORG00000010001 | 9796 | Equus caballus | ENSECAG00000010160 |
| 9365 | Erinaceus europaeus | ENSEEUG00000008977 | 9371 | Echinops telfairi | ENSETEG00000016614 |
| 69293 | Gasterosteus aculeatus | ENSGACG00000020332 | 9031 | Gallus gallus | ENSGALG00000004596 |
| 8049 | Gadus morhua | ENSGMOG00000010216 | 7897 | Latimeria chalumnae | ENSLACG00000015024 |
| 9315 | Macropus eugenii | ENSMEUG00000016129 | 9103 | Meleagris gallopavo | ENSMGAG00000010900 |
| 30608 | Microcebus murinus | ENSMICG00000014721 | 9544 | Macaca mulatta | ENSMMUG00000011437 |
| 13616 | Monodelphis domestica | ENSMODG00000012412 | 61853 | Nomascus leucogenys | ENSNLEG00000000573 |
| 9258 | Ornithorhynchus anatinus | ENSOANG00000010494 | 8128 | Oreochromis niloticus | ENSONIG00000012854 |
| 9978 | Ochotona princeps | ENSOPRG00000013315 | 8090 | Oryzias latipes | ENSORLG00000009520 |
| 7757 | Petromyzon marinus | ENSPMAG00000005858 | 13735 | Pelodiscus sinensis | ENSPSIG00000010176 |
| 9598 | Pan troglodytes | ENSPTRG00000004206 | 132908 | Pteropus vampyrus | ENSPVAG00000001117 |
| 42254 | Sorex araneus | ENSSARG00000005970 | 9305 | Sarcophilus harrisii | ENSSHAG00000016645 |
| 9823 | Sus scrofa | ENSSSCG00000012371 | 37347 | Tupaia belangeri | ENSTBEG00000015310 |
| 59729 | Taeniopygia guttata | ENSTGUG00000002760 | 99883 | Tetraodon nigroviridis | ENSTNIG00000011826 |
| 31033 | Takifugu rubripes | ENSTRUG00000012421 | 9478 | Tarsius syrichta | ENSTSYG00000009965 |
| 9739 | Tursiops truncatus | ENSTTRG00000004230 | 8364 | Xenopus tropicalis | ENSXETG00000005089 |
| 9986 | Oryctolagus cuniculus | 100009193 | 9646 | Ailuropoda melanoleuca | 100464952 |
| 39432 | Saimiri boliviensis | 101040429 | 9685 | Felis catus | 101081787 |
| 9595 | Gorilla gorilla | 101152212 | 9813 | Procavia capensis | ENSPCAG00000015018 |
| 30538 | Vicugna pacos | ENSVPAG00000008979 | |||