Basic Information | |||
Gene ID | 5241 ; Check Expression Profles ; Check TFs & Targets Binding | ||
Gene Name | PGR; NR3C3 | ||
Full Name | Progesterone receptor | ||
Organism | Homo sapiens [9606] |
Cross Reference | |||
UniProt | P06401 | UniGene | Hs.742403 |
PDB | 4APU | OMIM | 607311 |
KEGG | hsa:5241 | UCSC | uc001pgh.2 |
Protein Interactions | |
DIP | DIP-5967N |
IntAct | P06401 |
MINT | MINT-1505587 |
STRING | 9606.ENSP00000325120 |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
ENSEMBL | |||
ENSEMBL | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSP00000325120 | Gene3D | G3DSA:1.10.565.10 | IPR008946 | 665 | 916 | 2.10e-73 | Nuclear hormone receptor, ligand-binding |
ENSP00000325120 | Gene3D | G3DSA:3.30.50.10 | IPR013088 | 563 | 634 | 1.50e-24 | Zinc finger, NHR/GATA-type |
ENSP00000325120 | Pfam | PF00104 | IPR000536 | 702 | 883 | 2.50e-27 | Nuclear hormone receptor, ligand-binding, core |
ENSP00000325120 | Pfam | PF00105 | IPR001628 | 566 | 633 | 3.10e-26 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | Pfam | PF02161 | IPR000128 | 1 | 564 | 1.80e-272 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00047 | IPR001628 | 567 | 583 | 2.10e-13 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | PRINTS | PR00047 | IPR001628 | 583 | 598 | 2.10e-13 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | PRINTS | PR00047 | IPR001628 | 616 | 624 | 2.10e-13 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | PRINTS | PR00047 | IPR001628 | 624 | 632 | 2.10e-13 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | PRINTS | PR00398 | IPR001723 | 721 | 742 | 2.10e-12 | Steroid hormone receptor |
ENSP00000325120 | PRINTS | PR00398 | IPR001723 | 742 | 758 | 2.10e-12 | Steroid hormone receptor |
ENSP00000325120 | PRINTS | PR00398 | IPR001723 | 811 | 826 | 2.10e-12 | Steroid hormone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 104 | 121 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 137 | 151 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 302 | 324 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 349 | 365 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 48 | 64 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 506 | 522 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 523 | 542 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | PRINTS | PR00544 | IPR000128 | 544 | 563 | 2.70e-93 | Progesterone receptor |
ENSP00000325120 | ProSitePatterns | PS00031 | IPR001628 | 567 | 593 | - | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | ProSiteProfiles | PS51030 | IPR001628 | 564 | 639 | 0.00e-00 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | SMART | SM00399 | IPR001628 | 564 | 635 | 4.30e-32 | Zinc finger, nuclear hormone receptor-type |
ENSP00000325120 | SMART | SM00430 | IPR000536 | 720 | 884 | 8.00e-36 | Nuclear hormone receptor, ligand-binding, core |
ENSP00000325120 | SUPERFAMILY | SSF48508 | IPR008946 | 617 | 643 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
ENSP00000325120 | SUPERFAMILY | SSF48508 | IPR008946 | 674 | 913 | 0.00e-00 | Nuclear hormone receptor, ligand-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSP00000325120 | PF02161 | 0 | Prog_receptor | Progesterone receptor |
ENSP00000325120 | PF00104 | 1.8e-27 | Hormone_recep | Ligand-binding domain of nuclear hormone receptor |
ENSP00000325120 | PF00105 | 2e-26 | zf-C4 | Zinc finger, C4 type (two domains) |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSP00000325120 | GO:0006351 | biological_process | transcription, DNA-templated |
ENSP00000325120 | GO:0006355 | biological_process | regulation of transcription, DNA-templated |
ENSP00000325120 | GO:0043401 | biological_process | steroid hormone mediated signaling pathway |
ENSP00000325120 | GO:0005634 | cellular_component | nucleus |
ENSP00000325120 | GO:0005737 | cellular_component | cytoplasm |
ENSP00000325120 | GO:0003677 | molecular_function | DNA binding |
ENSP00000325120 | GO:0003700 | molecular_function | sequence-specific DNA binding transcription factor activity |
ENSP00000325120 | GO:0003707 | molecular_function | steroid hormone receptor activity |
ENSP00000325120 | GO:0005496 | molecular_function | steroid binding |
ENSP00000325120 | GO:0008270 | molecular_function | zinc ion binding |
ENSP00000325120 | GO:0008289 | molecular_function | lipid binding |
ENSP00000325120 | GO:0043565 | molecular_function | sequence-specific DNA binding |
ENSP00000325120 | GO:0046872 | molecular_function | metal ion binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
7955 | Danio rerio | 100005148 | 9986 | Oryctolagus cuniculus | 100009094 |
9555 | Papio anubis | 100303420 | 9483 | Callithrix jacchus | 100395871 |
9601 | Pongo abelii | 100454831 | 30611 | Otolemur garnettii | 100945812 |
9597 | Pan paniscus | 100989324 | 39432 | Saimiri boliviensis | 101046070 |
9595 | Gorilla gorilla | 101152212 | 9669 | Mustela putorius furo | 101680284 |
8083 | Xiphophorus maculatus | 102233217 | 10029 | Cricetulus griseus | 100757656 |
9796 | Equus caballus | ENSECAG00000011511 | 9031 | Gallus gallus | ENSGALG00000017195 |
30608 | Microcebus murinus | ENSMICG00000006331 | 13735 | Pelodiscus sinensis | ENSPSIG00000013654 |
9823 | Sus scrofa | ENSSSCG00000014977 | 31033 | Takifugu rubripes | ENSTRUG00000013128 |
9544 | Macaca mulatta | 613024 | 28377 | Anolis carolinensis | ENSACAG00000013594 |
9646 | Ailuropoda melanoleuca | ENSAMEG00000017449 | 9913 | Bos taurus | ENSBTAG00000024648 |
9615 | Canis familiaris | ENSCAFG00000003978 | 9358 | Choloepus hoffmanni | ENSCHOG00000007092 |
10141 | Cavia porcellus | ENSCPOG00000020113 | 9371 | Echinops telfairi | ENSETEG00000009960 |
9685 | Felis catus | ENSFCAG00000011489 | 69293 | Gasterosteus aculeatus | ENSGACG00000012162 |
8049 | Gadus morhua | ENSGMOG00000002886 | 7897 | Latimeria chalumnae | ENSLACG00000013150 |
9785 | Loxodonta africana | ENSLAFG00000006479 | 9315 | Macropus eugenii | ENSMEUG00000015727 |
9103 | Meleagris gallopavo | ENSMGAG00000015180 | 59463 | Myotis lucifugus | ENSMLUG00000022851 |
13616 | Monodelphis domestica | ENSMODG00000000509 | 61853 | Nomascus leucogenys | ENSNLEG00000007154 |
9258 | Ornithorhynchus anatinus | ENSOANG00000010494 | 9978 | Ochotona princeps | ENSOPRG00000008534 |
9813 | Procavia capensis | ENSPCAG00000013031 | 7757 | Petromyzon marinus | ENSPMAG00000005858 |
9598 | Pan troglodytes | ENSPTRG00000004206 | 132908 | Pteropus vampyrus | ENSPVAG00000006626 |
10116 | Rattus norvegicus | ENSRNOG00000006831 | 9305 | Sarcophilus harrisii | ENSSHAG00000016670 |
43179 | Ictidomys tridecemlineatus | ENSSTOG00000020694 | 37347 | Tupaia belangeri | ENSTBEG00000009619 |
59729 | Taeniopygia guttata | ENSTGUG00000012778 | 99883 | Tetraodon nigroviridis | ENSTNIG00000019045 |
9739 | Tursiops truncatus | ENSTTRG00000000030 | 30538 | Vicugna pacos | ENSVPAG00000008979 |
8364 | Xenopus tropicalis | ENSXETG00000005089 |