Basic Information | |||
Gene ID | 100054693 | ||
Gene Name | STAT4 | ||
Full Name | Signal transducer and activator of transcription | ||
Organism | Equus caballus [9796] |
Cross Reference | |||
UniProt | F7CJM0 | UniGene | NULL |
PDB | NULL | OMIM | NULL |
KEGG | NULL | UCSC | NULL |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | NULL |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
ENSECAP00000021075 | Gene3D | G3DSA:1.10.238.10 | IPR011992 | 457 | 577 | 1.40e-49 | EF-hand domain pair |
ENSECAP00000021075 | Gene3D | G3DSA:1.10.532.10 | IPR013799 | 1 | 121 | 3.50e-45 | STAT transcription factor, protein interaction |
ENSECAP00000021075 | Gene3D | G3DSA:1.20.1050.20 | IPR013800 | 138 | 316 | 1.00e-63 | STAT transcription factor, all-alpha |
ENSECAP00000021075 | Gene3D | G3DSA:2.60.40.630 | IPR012345 | 317 | 456 | 2.80e-57 | STAT transcription factor, DNA-binding, subdomain |
ENSECAP00000021075 | Gene3D | G3DSA:3.30.505.10 | IPR000980 | 578 | 703 | 6.60e-50 | SH2 domain |
ENSECAP00000021075 | PANTHER | PTHR11801 | IPR001217 | 2 | 741 | 0.00e-00 | Transcription factor STAT |
ENSECAP00000021075 | Pfam | PF00017 | IPR000980 | 573 | 627 | 2.60e-11 | SH2 domain |
ENSECAP00000021075 | Pfam | PF01017 | IPR013800 | 137 | 314 | 1.80e-64 | STAT transcription factor, all-alpha |
ENSECAP00000021075 | Pfam | PF02864 | IPR013801 | 316 | 563 | 4.00e-113 | STAT transcription factor, DNA-binding |
ENSECAP00000021075 | Pfam | PF02865 | IPR013799 | 2 | 121 | 1.80e-42 | STAT transcription factor, protein interaction |
ENSECAP00000021075 | ProSiteProfiles | PS50001 | IPR000980 | 569 | 647 | 0.00e-00 | SH2 domain |
ENSECAP00000021075 | SMART | SM00252 | IPR000980 | 571 | 681 | 5.70e-03 | SH2 domain |
ENSECAP00000021075 | SMART | SM00964 | IPR013799 | 2 | 122 | 7.70e-66 | STAT transcription factor, protein interaction |
ENSECAP00000021075 | SUPERFAMILY | SSF47655 | IPR015988 | 136 | 316 | 0.00e-00 | STAT transcription factor, coiled coil |
ENSECAP00000021075 | SUPERFAMILY | SSF48092 | IPR013799 | 1 | 121 | 0.00e-00 | STAT transcription factor, protein interaction |
ENSECAP00000021075 | SUPERFAMILY | SSF49417 | IPR008967 | 316 | 564 | 0.00e-00 | p53-like transcription factor, DNA-binding |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
ENSECAP00000021075 | PF01017 | 0 | STAT_alpha | STAT protein, all-alpha domain |
ENSECAP00000021075 | PF02864 | 0 | STAT_bind | STAT protein, DNA binding domain |
ENSECAP00000021075 | PF02865 | 1.80067e-42 | STAT_int | STAT protein, protein interaction domain |
ENSECAP00000021075 | PF00017 | 4e-12 | SH2 | SH2 domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
ENSECAP00000021075 | GO:0006357 | biological_process | regulation of transcription from RNA polymerase II promoter |
ENSECAP00000021075 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
ENSECAP00000021075 | GO:0045944 | biological_process | positive regulation of transcription from RNA polymerase II promoter |
ENSECAP00000021075 | GO:0005634 | cellular_component | nucleus |
ENSECAP00000021075 | GO:0005737 | cellular_component | cytoplasm |
ENSECAP00000021075 | GO:0003677 | molecular_function | DNA binding |
ENSECAP00000021075 | GO:0004871 | molecular_function | signal transducer activity |
ENSECAP00000021075 | GO:0005509 | molecular_function | calcium ion binding |
ENSECAP00000021075 | GO:0043565 | molecular_function | sequence-specific DNA binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9483 | Callithrix jacchus | 100402355 | 10029 | Cricetulus griseus | 100769249 |
9597 | Pan paniscus | 100972895 | 9555 | Papio anubis | 101007479 |
39432 | Saimiri boliviensis | 101030273 | 31033 | Takifugu rubripes | 101068057 |
10090 | Mus musculus | 20849 | 9606 | Homo sapiens | 6775 |
9358 | Choloepus hoffmanni | ENSCHOG00000006838 | 10020 | Dipodomys ordii | ENSDORG00000011535 |
9365 | Erinaceus europaeus | ENSEEUG00000002778 | 9371 | Echinops telfairi | ENSETEG00000017045 |
9685 | Felis catus | ENSFCAG00000018634 | 69293 | Gasterosteus aculeatus | ENSGACG00000002684 |
9031 | Gallus gallus | ENSGALG00000025974 | 8049 | Gadus morhua | ENSGMOG00000008284 |
9785 | Loxodonta africana | ENSLAFG00000012299 | 9315 | Macropus eugenii | ENSMEUG00000016504 |
30608 | Microcebus murinus | ENSMICG00000002951 | 9544 | Macaca mulatta | ENSMMUG00000005617 |
9669 | Mustela putorius furo | ENSMPUG00000012539 | 9258 | Ornithorhynchus anatinus | ENSOANG00000022251 |
30611 | Otolemur garnettii | ENSOGAG00000003042 | 8128 | Oreochromis niloticus | ENSONIG00000016817 |
9978 | Ochotona princeps | ENSOPRG00000008636 | 8090 | Oryzias latipes | ENSORLG00000015180 |
9813 | Procavia capensis | ENSPCAG00000006029 | 9601 | Pongo abelii | ENSPPYG00000013028 |
132908 | Pteropus vampyrus | ENSPVAG00000004736 | 42254 | Sorex araneus | ENSSARG00000007166 |
9823 | Sus scrofa | ENSSSCG00000016059 | 37347 | Tupaia belangeri | ENSTBEG00000017692 |
99883 | Tetraodon nigroviridis | ENSTNIG00000017860 | 9478 | Tarsius syrichta | ENSTSYG00000001302 |
9739 | Tursiops truncatus | ENSTTRG00000001136 | 30538 | Vicugna pacos | ENSVPAG00000011545 |
8364 | Xenopus tropicalis | ENSXETG00000004662 |