Basic Information
Gene ID ENSXETG00000004662
Gene Name stat4
Full Name Signal transducer and activator of transcription
Organism Xenopus tropicalis [8364]

Cross Reference
UniProt F6UJ81 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXETP00000010124 Gene3D G3DSA:1.10.238.10 IPR011992 366 487 1.70e-48 EF-hand domain pair
ENSXETP00000010124 Gene3D G3DSA:1.20.1050.20 IPR013800 47 225 1.20e-57 STAT transcription factor, all-alpha
ENSXETP00000010124 Gene3D G3DSA:2.60.40.630 IPR012345 226 365 2.60e-53 STAT transcription factor, DNA-binding, subdomain
ENSXETP00000010124 Gene3D G3DSA:3.30.505.10 IPR000980 488 611 8.10e-46 SH2 domain
ENSXETP00000010124 PANTHER PTHR11801 IPR001217 1 656 0.00e-00 Transcription factor STAT
ENSXETP00000010124 Pfam PF00017 IPR000980 484 537 1.80e-09 SH2 domain
ENSXETP00000010124 Pfam PF01017 IPR013800 46 222 1.60e-57 STAT transcription factor, all-alpha
ENSXETP00000010124 Pfam PF02864 IPR013801 225 473 8.50e-104 STAT transcription factor, DNA-binding
ENSXETP00000010124 ProSiteProfiles PS50001 IPR000980 479 617 0.00e-00 SH2 domain
ENSXETP00000010124 SMART SM00252 IPR000980 481 561 7.40e-03 SH2 domain
ENSXETP00000010124 SUPERFAMILY SSF47655 IPR015988 45 225 0.00e-00 STAT transcription factor, coiled coil
ENSXETP00000010124 SUPERFAMILY SSF49417 IPR008967 226 474 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXETP00000010124 PF01017 0 STAT_alpha STAT protein, all-alpha domain
ENSXETP00000010124 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSXETP00000010124 PF00017 4.8e-10 SH2 SH2 domain
ENSXETP00000010124 PF02865 4.6e-05 STAT_int STAT protein, protein interaction domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXETP00000010124 GO:0006357 biological_process regulation of transcription from RNA polymerase II promoter
ENSXETP00000010124 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSXETP00000010124 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSXETP00000010124 GO:0005634 cellular_component nucleus
ENSXETP00000010124 GO:0005737 cellular_component cytoplasm
ENSXETP00000010124 GO:0004871 molecular_function signal transducer activity
ENSXETP00000010124 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
39432 Saimiri boliviensis 101030273 31033 Takifugu rubripes 101068057
10090 Mus musculus 20849 9606 Homo sapiens 6775
9358 Choloepus hoffmanni ENSCHOG00000006838 9365 Erinaceus europaeus ENSEEUG00000002778
9371 Echinops telfairi ENSETEG00000017045 69293 Gasterosteus aculeatus ENSGACG00000002684
9031 Gallus gallus ENSGALG00000025974 8049 Gadus morhua ENSGMOG00000008284
9785 Loxodonta africana ENSLAFG00000012299 30608 Microcebus murinus ENSMICG00000002951
9669 Mustela putorius furo ENSMPUG00000012539 9258 Ornithorhynchus anatinus ENSOANG00000022251
30611 Otolemur garnettii ENSOGAG00000003042 8128 Oreochromis niloticus ENSONIG00000016817
9978 Ochotona princeps ENSOPRG00000008636 8090 Oryzias latipes ENSORLG00000015180
9601 Pongo abelii ENSPPYG00000013028 132908 Pteropus vampyrus ENSPVAG00000004736
37347 Tupaia belangeri ENSTBEG00000017692 99883 Tetraodon nigroviridis ENSTNIG00000017860
9478 Tarsius syrichta ENSTSYG00000001302 9739 Tursiops truncatus ENSTTRG00000001136
9796 Equus caballus 100054693 9483 Callithrix jacchus 100402355
9597 Pan paniscus 100972895 9555 Papio anubis 101007479
10020 Dipodomys ordii ENSDORG00000011535 9685 Felis catus ENSFCAG00000018634
9544 Macaca mulatta ENSMMUG00000005617 9813 Procavia capensis ENSPCAG00000006029
42254 Sorex araneus ENSSARG00000007166 9823 Sus scrofa ENSSSCG00000016059
30538 Vicugna pacos ENSVPAG00000011545