Basic Information
Gene ID 100556024
Gene Name TFAP4
Full Name Uncharacterized protein
Organism Anolis carolinensis [28377]

Cross Reference
UniProt H9GN57 UniGene NULL
PDB NULL OMIM NULL
KEGG acs:100556024 UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSACAP00000016086 Gene3D G3DSA:4.10.280.10 IPR011598 54 125 4.30e-20 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016086 Pfam PF00010 IPR011598 54 105 4.70e-17 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016086 ProSiteProfiles PS50888 IPR011598 53 104 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016086 SMART SM00353 IPR011598 59 110 7.10e-19 Myc-type, basic helix-loop-helix (bHLH) domain
ENSACAP00000016086 SUPERFAMILY SSF47459 IPR011598 45 119 0.00e-00 Myc-type, basic helix-loop-helix (bHLH) domain

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSACAP00000016086 PF00010 4.7e-17 HLH Helix-loop-helix DNA-binding domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSACAP00000016086 GO:0006366 biological_process transcription from RNA polymerase II promoter
ENSACAP00000016086 GO:0006461 biological_process protein complex assembly
ENSACAP00000016086 GO:0006978 biological_process DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ENSACAP00000016086 GO:0008285 biological_process negative regulation of cell proliferation
ENSACAP00000016086 GO:0043065 biological_process positive regulation of apoptotic process
ENSACAP00000016086 GO:0043066 biological_process negative regulation of apoptotic process
ENSACAP00000016086 GO:0043392 biological_process negative regulation of DNA binding
ENSACAP00000016086 GO:0043922 biological_process negative regulation by host of viral transcription
ENSACAP00000016086 GO:0043923 biological_process positive regulation by host of viral transcription
ENSACAP00000016086 GO:0045736 biological_process negative regulation of cyclin-dependent protein serine/threonine kinase activity
ENSACAP00000016086 GO:0045892 biological_process negative regulation of transcription, DNA-templated
ENSACAP00000016086 GO:0045893 biological_process positive regulation of transcription, DNA-templated
ENSACAP00000016086 GO:0071157 biological_process negative regulation of cell cycle arrest
ENSACAP00000016086 GO:0071549 biological_process cellular response to dexamethasone stimulus
ENSACAP00000016086 GO:2001269 biological_process positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
ENSACAP00000016086 GO:0005634 cellular_component nucleus
ENSACAP00000016086 GO:0017053 cellular_component transcriptional repressor complex
ENSACAP00000016086 GO:0000978 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding
ENSACAP00000016086 GO:0001077 molecular_function RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
ENSACAP00000016086 GO:0003677 molecular_function DNA binding
ENSACAP00000016086 GO:0003705 molecular_function RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
ENSACAP00000016086 GO:0003713 molecular_function transcription coactivator activity
ENSACAP00000016086 GO:0005515 molecular_function protein binding
ENSACAP00000016086 GO:0042803 molecular_function protein homodimerization activity
ENSACAP00000016086 GO:0042826 molecular_function histone deacetylase binding
ENSACAP00000016086 GO:0043565 molecular_function sequence-specific DNA binding
ENSACAP00000016086 GO:0044212 molecular_function transcription regulatory region DNA binding
ENSACAP00000016086 GO:0046982 molecular_function protein heterodimerization activity
ENSACAP00000016086 GO:0070888 molecular_function E-box binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9796 Equus caballus 100069711 7029 Acyrthosiphon pisum 100161809
10224 Saccoglossus kowalevskii 100375636 9483 Callithrix jacchus 100391868
9646 Ailuropoda melanoleuca 100474477 30195 Bombus terrestris 100644452
9785 Loxodonta africana 100663165 7425 Nasonia vitripennis 100679356
10141 Cavia porcellus 100718065 132113 Bombus impatiens 100748243
10029 Cricetulus griseus 100751080 143995 Megachile rotundata 100883438
9305 Sarcophilus harrisii 100925765 9597 Pan paniscus 100983876
9555 Papio anubis 101005019 39432 Saimiri boliviensis 101043319
9685 Felis catus 101095461 9595 Gorilla gorilla 101146500
8090 Oryzias latipes 101175405 43179 Ictidomys tridecemlineatus 101973956
7227 Drosophila melanogaster 34956 10116 Rattus norvegicus 360482
7070 Tribolium castaneum 656093 7460 Apis mellifera 726729
7719 Ciona intestinalis ENSCING00000014406 51511 Ciona savignyi ENSCSAVG00000000333
10020 Dipodomys ordii ENSDORG00000004656 9371 Echinops telfairi ENSETEG00000008634
8049 Gadus morhua ENSGMOG00000014930 7897 Latimeria chalumnae ENSLACG00000000328
9315 Macropus eugenii ENSMEUG00000000888 9986 Oryctolagus cuniculus ENSOCUG00000024550
9978 Ochotona princeps ENSOPRG00000001061 9598 Pan troglodytes ENSPTRG00000007713
132908 Pteropus vampyrus ENSPVAG00000005418 59729 Taeniopygia guttata ENSTGUG00000003940
99883 Tetraodon nigroviridis ENSTNIG00000009740 31033 Takifugu rubripes ENSTRUG00000006111
9739 Tursiops truncatus ENSTTRG00000002710 30538 Vicugna pacos ENSVPAG00000008001
400682 Amphimedon queenslandica 100635737 34638 Metaseiulus occidentalis 100902969
30611 Otolemur garnettii 100944090 8083 Xiphophorus maculatus 102231357
59463 Myotis lucifugus 102420659 7668 Strongylocentrotus purpuratus 578637
9365 Erinaceus europaeus ENSEEUG00000006004 69293 Gasterosteus aculeatus ENSGACG00000011329
9031 Gallus gallus ENSGALG00000027823 9103 Meleagris gallopavo ENSMGAG00000009411
9669 Mustela putorius furo ENSMPUG00000015023 9258 Ornithorhynchus anatinus ENSOANG00000019858
9813 Procavia capensis ENSPCAG00000011134 9601 Pongo abelii ENSPPYG00000007054
13735 Pelodiscus sinensis ENSPSIG00000009002 37347 Tupaia belangeri ENSTBEG00000014089
9478 Tarsius syrichta ENSTSYG00000009292