Basic Information | |||
Gene ID | 34956 | ||
Gene Name | crp; AP-4, crp-RA; CG7664, Dmel_CG7664 | ||
Full Name | Activator protein 4 | ||
Organism | Drosophila melanogaster [7227] |
Cross Reference | |||
UniProt | Q9V406 | UniGene | Dm.6530 |
PDB | NULL | OMIM | NULL |
KEGG | dme:Dmel_CG7664 | UCSC | CG7664-RA |
Protein Interactions | |
DIP | NULL |
IntAct | NULL |
MINT | MINT-860868 |
STRING | NULL |
Ensembl/RefSeq | Transcript ID | Protein ID | Gene ID |
ENSEMBL | |||
REFSEQ |
InterPro Annotation | |||||||
Protein | Program | Term | IPRS | Start | End | Score | Description |
FBpp0080411 | Gene3D | G3DSA:4.10.280.10 | IPR011598 | 97 | 166 | 4.10e-17 | Myc-type, basic helix-loop-helix (bHLH) domain |
FBpp0080411 | Pfam | PF00010 | IPR011598 | 97 | 147 | 7.60e-15 | Myc-type, basic helix-loop-helix (bHLH) domain |
FBpp0080411 | ProSiteProfiles | PS50888 | IPR011598 | 96 | 147 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
FBpp0080411 | SMART | SM00353 | IPR011598 | 102 | 153 | 3.80e-17 | Myc-type, basic helix-loop-helix (bHLH) domain |
FBpp0080411 | SUPERFAMILY | SSF47459 | IPR011598 | 97 | 168 | 0.00e-00 | Myc-type, basic helix-loop-helix (bHLH) domain |
Pfam Annotation | ||||
Protein | Pfam ID | E.value | Name | Description |
FBpp0080411 | PF00010 | 7.6e-15 | HLH | Helix-loop-helix DNA-binding domain |
Gene Ontology Annotation | |||
Protein | Entry | Name Space | Description |
FBpp0080411 | GO:0006366 | biological_process | transcription from RNA polymerase II promoter |
FBpp0080411 | GO:0006461 | biological_process | protein complex assembly |
FBpp0080411 | GO:0006978 | biological_process | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator |
FBpp0080411 | GO:0008285 | biological_process | negative regulation of cell proliferation |
FBpp0080411 | GO:0043065 | biological_process | positive regulation of apoptotic process |
FBpp0080411 | GO:0043066 | biological_process | negative regulation of apoptotic process |
FBpp0080411 | GO:0043392 | biological_process | negative regulation of DNA binding |
FBpp0080411 | GO:0043922 | biological_process | negative regulation by host of viral transcription |
FBpp0080411 | GO:0043923 | biological_process | positive regulation by host of viral transcription |
FBpp0080411 | GO:0045736 | biological_process | negative regulation of cyclin-dependent protein serine/threonine kinase activity |
FBpp0080411 | GO:0045892 | biological_process | negative regulation of transcription, DNA-templated |
FBpp0080411 | GO:0045893 | biological_process | positive regulation of transcription, DNA-templated |
FBpp0080411 | GO:0071157 | biological_process | negative regulation of cell cycle arrest |
FBpp0080411 | GO:0071549 | biological_process | cellular response to dexamethasone stimulus |
FBpp0080411 | GO:2001269 | biological_process | positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway |
FBpp0080411 | GO:0005634 | cellular_component | nucleus |
FBpp0080411 | GO:0017053 | cellular_component | transcriptional repressor complex |
FBpp0080411 | GO:0000978 | molecular_function | RNA polymerase II core promoter proximal region sequence-specific DNA binding |
FBpp0080411 | GO:0001077 | molecular_function | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription |
FBpp0080411 | GO:0003677 | molecular_function | DNA binding |
FBpp0080411 | GO:0003705 | molecular_function | RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity |
FBpp0080411 | GO:0003713 | molecular_function | transcription coactivator activity |
FBpp0080411 | GO:0005515 | molecular_function | protein binding |
FBpp0080411 | GO:0042803 | molecular_function | protein homodimerization activity |
FBpp0080411 | GO:0042826 | molecular_function | histone deacetylase binding |
FBpp0080411 | GO:0043565 | molecular_function | sequence-specific DNA binding |
FBpp0080411 | GO:0044212 | molecular_function | transcription regulatory region DNA binding |
FBpp0080411 | GO:0046982 | molecular_function | protein heterodimerization activity |
FBpp0080411 | GO:0070888 | molecular_function | E-box binding |
Orthologs | |||||
TAXID | Organism | Gene ID | TAXID | Organism | Gene ID |
9796 | Equus caballus | 100069711 | 10224 | Saccoglossus kowalevskii | 100375636 |
28377 | Anolis carolinensis | 100556024 | 10141 | Cavia porcellus | 100718065 |
34638 | Metaseiulus occidentalis | 100902969 | 30611 | Otolemur garnettii | 100944090 |
9685 | Felis catus | 101095461 | 9595 | Gorilla gorilla | 101146500 |
8083 | Xiphophorus maculatus | 102231357 | 59463 | Myotis lucifugus | 102420659 |
7029 | Acyrthosiphon pisum | 100161809 | 9483 | Callithrix jacchus | 100391868 |
9646 | Ailuropoda melanoleuca | 100474477 | 30195 | Bombus terrestris | 100644452 |
9785 | Loxodonta africana | 100663165 | 132113 | Bombus impatiens | 100748243 |
10029 | Cricetulus griseus | 100751080 | 143995 | Megachile rotundata | 100883438 |
9305 | Sarcophilus harrisii | 100925765 | 9597 | Pan paniscus | 100983876 |
9555 | Papio anubis | 101005019 | 39432 | Saimiri boliviensis | 101043319 |
8090 | Oryzias latipes | 101175405 | 43179 | Ictidomys tridecemlineatus | 101973956 |
10116 | Rattus norvegicus | 360482 | 7070 | Tribolium castaneum | 656093 |
7460 | Apis mellifera | 726729 | 7719 | Ciona intestinalis | ENSCING00000014406 |
51511 | Ciona savignyi | ENSCSAVG00000000333 | 10020 | Dipodomys ordii | ENSDORG00000004656 |
8049 | Gadus morhua | ENSGMOG00000014930 | 7897 | Latimeria chalumnae | ENSLACG00000000328 |
9986 | Oryctolagus cuniculus | ENSOCUG00000024550 | 9598 | Pan troglodytes | ENSPTRG00000007713 |
132908 | Pteropus vampyrus | ENSPVAG00000005418 | 9739 | Tursiops truncatus | ENSTTRG00000002710 |
30538 | Vicugna pacos | ENSVPAG00000008001 | 7668 | Strongylocentrotus purpuratus | 578637 |
9365 | Erinaceus europaeus | ENSEEUG00000006004 | 9371 | Echinops telfairi | ENSETEG00000008634 |
69293 | Gasterosteus aculeatus | ENSGACG00000011329 | 9315 | Macropus eugenii | ENSMEUG00000000888 |
9103 | Meleagris gallopavo | ENSMGAG00000009411 | 9669 | Mustela putorius furo | ENSMPUG00000015023 |
9258 | Ornithorhynchus anatinus | ENSOANG00000019858 | 9978 | Ochotona princeps | ENSOPRG00000001061 |
9813 | Procavia capensis | ENSPCAG00000011134 | 9601 | Pongo abelii | ENSPPYG00000007054 |
13735 | Pelodiscus sinensis | ENSPSIG00000009002 | 37347 | Tupaia belangeri | ENSTBEG00000014089 |
99883 | Tetraodon nigroviridis | ENSTNIG00000009740 | 31033 | Takifugu rubripes | ENSTRUG00000006111 |