Basic Information
Gene ID 100704348
Gene Name LOC100704348
Full Name Signal transducer and activator of transcription
Organism Oreochromis niloticus [8128]

Cross Reference
UniProt I3K1M6 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL
REFSEQ

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSONIP00000015021 Gene3D G3DSA:1.10.238.10 IPR011992 437 561 1.60e-40 EF-hand domain pair
ENSONIP00000015021 Gene3D G3DSA:1.10.532.10 IPR013799 1 119 4.90e-23 STAT transcription factor, protein interaction
ENSONIP00000015021 Gene3D G3DSA:1.20.1050.20 IPR013800 136 286 2.00e-17 STAT transcription factor, all-alpha
ENSONIP00000015021 Gene3D G3DSA:2.60.40.630 IPR012345 302 436 1.20e-40 STAT transcription factor, DNA-binding, subdomain
ENSONIP00000015021 Gene3D G3DSA:3.30.505.10 IPR000980 562 667 1.30e-33 SH2 domain
ENSONIP00000015021 PANTHER PTHR11801 IPR001217 2 735 0.00e-00 Transcription factor STAT
ENSONIP00000015021 Pfam PF00017 IPR000980 558 611 1.60e-06 SH2 domain
ENSONIP00000015021 Pfam PF01017 IPR013800 136 284 2.20e-09 STAT transcription factor, all-alpha
ENSONIP00000015021 Pfam PF02864 IPR013801 301 547 8.70e-68 STAT transcription factor, DNA-binding
ENSONIP00000015021 Pfam PF02865 IPR013799 2 120 6.40e-27 STAT transcription factor, protein interaction
ENSONIP00000015021 ProSiteProfiles PS50001 IPR000980 553 653 0.00e-00 SH2 domain
ENSONIP00000015021 SMART SM00252 IPR000980 555 642 1.60e-04 SH2 domain
ENSONIP00000015021 SMART SM00964 IPR013799 2 124 9.60e-36 STAT transcription factor, protein interaction
ENSONIP00000015021 SUPERFAMILY SSF47655 IPR015988 136 301 0.00e-00 STAT transcription factor, coiled coil
ENSONIP00000015021 SUPERFAMILY SSF48092 IPR013799 1 119 0.00e-00 STAT transcription factor, protein interaction
ENSONIP00000015021 SUPERFAMILY SSF49417 IPR008967 294 548 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSONIP00000015021 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSONIP00000015021 PF02865 6.4e-27 STAT_int STAT protein, protein interaction domain
ENSONIP00000015021 PF01017 2.2e-09 STAT_alpha STAT protein, all-alpha domain
ENSONIP00000015021 PF00017 5.8e-07 SH2 SH2 domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSONIP00000015021 GO:0001553 biological_process luteinization
ENSONIP00000015021 GO:0001779 biological_process natural killer cell differentiation
ENSONIP00000015021 GO:0006351 biological_process transcription, DNA-templated
ENSONIP00000015021 GO:0007259 biological_process JAK-STAT cascade
ENSONIP00000015021 GO:0007565 biological_process female pregnancy
ENSONIP00000015021 GO:0007595 biological_process lactation
ENSONIP00000015021 GO:0019218 biological_process regulation of steroid metabolic process
ENSONIP00000015021 GO:0019915 biological_process lipid storage
ENSONIP00000015021 GO:0030155 biological_process regulation of cell adhesion
ENSONIP00000015021 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSONIP00000015021 GO:0038161 biological_process prolactin signaling pathway
ENSONIP00000015021 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSONIP00000015021 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSONIP00000015021 GO:0043029 biological_process T cell homeostasis
ENSONIP00000015021 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSONIP00000015021 GO:0045579 biological_process positive regulation of B cell differentiation
ENSONIP00000015021 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSONIP00000015021 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSONIP00000015021 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSONIP00000015021 GO:0046543 biological_process development of secondary female sexual characteristics
ENSONIP00000015021 GO:0050729 biological_process positive regulation of inflammatory response
ENSONIP00000015021 GO:0005634 cellular_component nucleus
ENSONIP00000015021 GO:0005737 cellular_component cytoplasm
ENSONIP00000015021 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSONIP00000015021 GO:0004871 molecular_function signal transducer activity
ENSONIP00000015021 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
9823 Sus scrofa 100627682 31033 Takifugu rubripes 101065277
9669 Mustela putorius furo 101676980 9544 Macaca mulatta 714159
28377 Anolis carolinensis ENSACAG00000009680 69293 Gasterosteus aculeatus ENSGACG00000008477
8049 Gadus morhua ENSGMOG00000008275 61853 Nomascus leucogenys ENSNLEG00000017396
9978 Ochotona princeps ENSOPRG00000013409 37347 Tupaia belangeri ENSTBEG00000013664
99883 Tetraodon nigroviridis ENSTNIG00000015103 9478 Tarsius syrichta ENSTSYG00000000267
8364 Xenopus tropicalis ENSXETG00000004431 8083 Xiphophorus maculatus ENSXMAG00000010611
9483 Callithrix jacchus ENSCJAG00000010327 30608 Microcebus murinus ENSMICG00000009087