Basic Information
Gene ID ENSXMAG00000010611
Gene Name NULL
Full Name Signal transducer and activator of transcription
Organism Xiphophorus maculatus [8083]

Cross Reference
UniProt M4A840 UniGene NULL
PDB NULL OMIM NULL
KEGG NULL UCSC NULL

Protein Interactions
DIP NULL
IntAct NULL
MINT NULL
STRING NULL

Ensembl/RefSeq
Transcript ID
Protein ID
Gene ID
ENSEMBL

InterPro Annotation
Protein Program Term IPRS Start End Score Description
ENSXMAP00000010634 Gene3D G3DSA:1.10.238.10 IPR011992 432 556 1.90e-40 EF-hand domain pair
ENSXMAP00000010634 Gene3D G3DSA:1.10.532.10 IPR013799 1 118 2.30e-20 STAT transcription factor, protein interaction
ENSXMAP00000010634 Gene3D G3DSA:1.20.1050.20 IPR013800 138 296 1.40e-09 STAT transcription factor, all-alpha
ENSXMAP00000010634 Gene3D G3DSA:2.60.40.630 IPR012345 297 431 7.30e-39 STAT transcription factor, DNA-binding, subdomain
ENSXMAP00000010634 Gene3D G3DSA:3.30.505.10 IPR000980 557 664 1.00e-33 SH2 domain
ENSXMAP00000010634 PANTHER PTHR11801 IPR001217 2 666 0.00e-00 Transcription factor STAT
ENSXMAP00000010634 Pfam PF00017 IPR000980 553 630 2.10e-07 SH2 domain
ENSXMAP00000010634 Pfam PF02864 IPR013801 296 542 9.30e-67 STAT transcription factor, DNA-binding
ENSXMAP00000010634 Pfam PF02865 IPR013799 2 117 3.20e-21 STAT transcription factor, protein interaction
ENSXMAP00000010634 ProSiteProfiles PS50001 IPR000980 548 664 0.00e-00 SH2 domain
ENSXMAP00000010634 SMART SM00252 IPR000980 554 636 1.90e-04 SH2 domain
ENSXMAP00000010634 SUPERFAMILY SSF47655 IPR015988 132 296 0.00e-00 STAT transcription factor, coiled coil
ENSXMAP00000010634 SUPERFAMILY SSF48092 IPR013799 1 116 0.00e-00 STAT transcription factor, protein interaction
ENSXMAP00000010634 SUPERFAMILY SSF49417 IPR008967 291 543 0.00e-00 p53-like transcription factor, DNA-binding

Pfam Annotation
Protein Pfam ID E.value Name Description
ENSXMAP00000010634 PF02864 0 STAT_bind STAT protein, DNA binding domain
ENSXMAP00000010634 PF02865 3.2e-21 STAT_int STAT protein, protein interaction domain
ENSXMAP00000010634 PF00017 5.6e-08 SH2 SH2 domain
ENSXMAP00000010634 PF01017 8.6e-06 STAT_alpha STAT protein, all-alpha domain

Gene Ontology Annotation
Protein Entry Name Space Description
ENSXMAP00000010634 GO:0001553 biological_process luteinization
ENSXMAP00000010634 GO:0001779 biological_process natural killer cell differentiation
ENSXMAP00000010634 GO:0006351 biological_process transcription, DNA-templated
ENSXMAP00000010634 GO:0007259 biological_process JAK-STAT cascade
ENSXMAP00000010634 GO:0007565 biological_process female pregnancy
ENSXMAP00000010634 GO:0007595 biological_process lactation
ENSXMAP00000010634 GO:0019218 biological_process regulation of steroid metabolic process
ENSXMAP00000010634 GO:0019915 biological_process lipid storage
ENSXMAP00000010634 GO:0030155 biological_process regulation of cell adhesion
ENSXMAP00000010634 GO:0030856 biological_process regulation of epithelial cell differentiation
ENSXMAP00000010634 GO:0038161 biological_process prolactin signaling pathway
ENSXMAP00000010634 GO:0040018 biological_process positive regulation of multicellular organism growth
ENSXMAP00000010634 GO:0042104 biological_process positive regulation of activated T cell proliferation
ENSXMAP00000010634 GO:0043029 biological_process T cell homeostasis
ENSXMAP00000010634 GO:0043066 biological_process negative regulation of apoptotic process
ENSXMAP00000010634 GO:0045086 biological_process positive regulation of interleukin-2 biosynthetic process
ENSXMAP00000010634 GO:0045579 biological_process positive regulation of B cell differentiation
ENSXMAP00000010634 GO:0045647 biological_process negative regulation of erythrocyte differentiation
ENSXMAP00000010634 GO:0045931 biological_process positive regulation of mitotic cell cycle
ENSXMAP00000010634 GO:0045944 biological_process positive regulation of transcription from RNA polymerase II promoter
ENSXMAP00000010634 GO:0046543 biological_process development of secondary female sexual characteristics
ENSXMAP00000010634 GO:0050729 biological_process positive regulation of inflammatory response
ENSXMAP00000010634 GO:0005634 cellular_component nucleus
ENSXMAP00000010634 GO:0005737 cellular_component cytoplasm
ENSXMAP00000010634 GO:0003700 molecular_function sequence-specific DNA binding transcription factor activity
ENSXMAP00000010634 GO:0004871 molecular_function signal transducer activity
ENSXMAP00000010634 GO:0005509 molecular_function calcium ion binding

Orthologs
TAXID Organism Gene ID TAXID Organism Gene ID
8128 Oreochromis niloticus 100704348 9597 Pan paniscus 100989067
9555 Papio anubis 101023204 39432 Saimiri boliviensis 101029869
31033 Takifugu rubripes 101065277 9595 Gorilla gorilla 101130575
9544 Macaca mulatta 714159 9483 Callithrix jacchus ENSCJAG00000010327
69293 Gasterosteus aculeatus ENSGACG00000008477 8049 Gadus morhua ENSGMOG00000008275
61853 Nomascus leucogenys ENSNLEG00000017396 9978 Ochotona princeps ENSOPRG00000013409
9601 Pongo abelii ENSPPYG00000004680 99883 Tetraodon nigroviridis ENSTNIG00000015103